About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Semaglutide
- Company
- Novo Nordisk
- Mechanism
- mono GLP-1
- Route
- Oral & injectable
- Recruiting trials
- 156 recruiting
156 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Find a Clinical Trial Near Me
See recruiting studies for Semaglutide and check eligibility with the study team.
Trial details
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Recruiting NCT NCT03884075
Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 104 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Non-Alcoholic Steatohepatitis, Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Recruiting NCT NCT04174755
Semaglutide's Efficacy in Achieving Weight Loss for Those With HIV
Not yet reported University College Dublin 80 participants Est. completion 2027-07 1 siteOther conditions: Obesity, HIV-1-infectionView official trial listing → -
Recruiting NCT NCT04873050
Treatment to Regress to Normoglycemia in Women with a Recent History of GDM
Not yet reported Woman's 102 participants Est. completion 2026-03-01 1 siteOther conditions: Pre Diabetes, Postpartum DisorderView official trial listing → -
Recruiting NCT NCT05071898
Pharmacogenetics of Response to GLP1R Agonists
Not yet reported University of Maryland, Baltimore 600 participants Est. completion 2028-04 1 site Stand-aloneOther conditions: Obesity, Diabetes Type 2View official trial listing → -
Recruiting NCT NCT05119179
Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes
Not yet reported The University of Texas Health Science Center, Houston 300 participants Est. completion 2026-10-31 1 sitePrediabetesView official trial listing → -
Recruiting NCT NCT05173714
Sit Less, Interact and Move More (SLIMM) 2 Study
Not yet reported Srinvasan Beddhu 156 participants Est. completion 2027-03-31 2 sites Stand-aloneChronic kidney disease Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT05305794
Effect of Weekly GLP1 Agonist Treatment in "Double Diabetes"
Not yet reported Centre Hospitalier Universitaire Dijon 76 participants Est. completion 2028-08 1 site Stand-aloneOther conditions: Double DiabetesView official trial listing → -
Recruiting NCT NCT05340868
Genetics of the Acute Response to Oral Semaglutide
Not yet reported Medical University of Bialystok 1000 participants Est. completion 2025-12-31 1 site Stand-alonePrediabetes Other conditions: Prediabetic State, ObesityView official trial listing → -
Recruiting NCT NCT05356104
GLP-1 Analogue in Preventing Progression of Small Vessel Disease (GAPP-SVD)
Not yet reported Chinese University of Hong Kong 110 participants Est. completion 2027-12 2 sitesOther conditions: Cerebral Small Vessel DiseaseView official trial listing → -
Recruiting NCT NCT05419726
Brown Adipose Tissue Activity in Response to Semaglutide Administered to Obese Subjects.
University of California, Los Angeles 20 participants Est. completion 2026-02-01 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT05424003
Randomized Double Blinded Placebo-Controlled w/Semaglutide to Prevent Weight Gain After Liver Transplant
Not yet reported University of Virginia 50 participants Est. completion 2026-08-01 1 site Stand-aloneMASLDView official trial listing → -
Recruiting NCT NCT05501483
Adipose Tissue Heterogeneity and Its Link to Type 2 Diabetes
Not yet reported Karolinska Institutet 60 participants Est. completion 2032-12-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT05569772
Semaglutide for the Treatment of Glucose Intolerance in Women With Prior Gestational Diabetes
Not yet reported Universitaire Ziekenhuizen KU Leuven 252 participants Est. completion 2029-12 13 sitesOther conditions: Glucose Intolerance After a Recent History of Gestational DiabetesView official trial listing → -
Recruiting NCT NCT05586802
Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter Syndrome
Not yet reported Georgios Papadakis 150 participants Est. completion 2027-04-30 1 site Stand-aloneOther conditions: Klinefelter SyndromeView official trial listing → -
Recruiting NCT NCT05630586
Acute Subcutaneous SemaglutidE in Acute Ischemic sTroke
Not yet reported Aarhus University Hospital 380 participants Est. completion 2027-12 1 siteCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT05700877
Screening and Intervention for Subclinical Coronary Artery Disease in Patients With Type 2 Diabetes
Not yet reported Per Løgstrup Poulsen 7300 participants Est. completion 2029-03-01 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT05702931
Semaglutide Treatment for Hyperglycaemia After Renal Transplantation
Not yet reported Rigshospitalet, Denmark 104 participants Est. completion 2027-12 1 siteOther conditions: Hyperglycemia, Renal Transplant Complication Primary Non-Function, DiabetesView official trial listing → -
Recruiting NCT NCT05746039
Feasibility of Semaglutide in Advanced Lung Disease
Not yet reported, Not yet reported University of Pennsylvania 8 participants Est. completion 2027-12-28 1 site Stand-aloneOther conditions: Obesity, Interstitial Lung Disease, Chronic Obstructive Pulmonary Disease, Sarcoidosis, Pulmonary, Pulmonary HypertensionView official trial listing → -
Recruiting NCT NCT05780905
Effects of Semaglutide on Intracranial Blood Flow and Brain-Barrier Permeability in Type-2 Diabetes
Not yet reported University of Washington 50 participants Est. completion 2026-12-31 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT05819138
Type 1 Diabetes Impacts of Semaglutide on Cardiovascular Outcomes
Not yet reported University of Colorado, Denver 60 participants Est. completion 2027-12-01 2 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Recruiting NCT NCT05819853
Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome
Not yet reported University of Colorado, Denver 80 participants Est. completion 2028-06-30 1 siteOther conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, ObeseView official trial listing → -
Recruiting NCT NCT05822609
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
Not yet reported University of Washington 60 participants Est. completion 2027-12 4 sites Stand-aloneChronic kidney disease Other conditions: Type 1 DiabetesView official trial listing → -
Recruiting NCT NCT05925959
Preoperative Weight Loss for Open Abdominal Wall Reconstruction
Not yet reported Benjamin T. Miller 258 participants Est. completion 2027-06-01 2 sitesOther conditions: Abdominal Wall HerniaView official trial listing → -
Recruiting NCT NCT05938712
The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Kidney Transplant Recipients
Not yet reported University Health Network, Toronto 20 participants Est. completion 2028-03-01 1 siteOther conditions: Kidney Transplant RecipientsView official trial listing → -
Recruiting NCT NCT06003153
GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH
Not yet reported Massachusetts General Hospital 125 participants Est. completion 2027-05-31 1 siteType 2 diabetes Other conditions: Genetic Predisposition, Metabolic DiseasesView official trial listing → -
Recruiting NCT NCT06060392
Effect of Oral Semaglutide on Liver Fat and Body Composition in Liver Transplant Recipients With Diabetes Mellitus
Not yet reported Medanta, The Medicity, India 50 participants Est. completion 2025-11-01 1 site Stand-aloneOther conditions: Liver Transplant; Complications, Diabete MellitusView official trial listing → -
Recruiting NCT NCT06069622
Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment
Brigham and Women's Hospital 30 participants Est. completion 2026-11-30 1 siteOther conditions: Overweight and ObesityView official trial listing → -
Recruiting NCT NCT06072963
COMMETS- Combination MCI Metabolic Syndrome
Not yet reported Rutgers, The State University of New Jersey 80 participants Est. completion 2028-12-01 1 site Stand-aloneMetabolic syndrome Other conditions: Alzheimer Disease, Mild Cognitive ImpairmentView official trial listing → -
Recruiting NCT NCT06082063
Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 2000 participants Est. completion 2029-07-01 2 sitesCardiovascular diseaseHeart failure Other conditions: Type 1 Diabetes, Kidney FailureView official trial listing → -
Recruiting NCT NCT06173778
Semaglutide for Post-Smoking Cessation Weight Management
Not yet reported The University of Texas Health Science Center, Houston 197 participants Est. completion 2026-08-01 2 sites Stand-aloneOther conditions: Obesity, Overweight, Cigarette SmokingView official trial listing → -
Recruiting NCT NCT06184633
DUTCH Weight Control in Atrial Fibrillation Study
Not yet reported Rijnstate Hospital 280 participants Est. completion 2027-05-01 1 siteOther conditions: Atrial Fibrillation, Obesity, Weight LossView official trial listing → -
Recruiting NCT NCT06271200
Strategic Lifestyle Intervention for Metabolic Syndrome (SLIM-MET)
Not yet reported National Health Research Institutes, Taiwan 200 participants Est. completion 2027-12-31 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Recruiting NCT NCT06318442
The GAPSID Study - How GLP-1 Analogues Prevent Steroid-Induced Diabetes
Not yet reported Imperial College London 60 participants Est. completion 2027-06-01 1 site Stand-aloneOther conditions: Steroid-Induced Diabetes, Steroid Induced HyperglycemiaView official trial listing → -
Recruiting NCT NCT06338553
GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab
Not yet reported Vanderbilt University Medical Center 24 participants Est. completion 2027-03 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Recruiting NCT NCT06374875
Fibrosis Lessens After Metabolic Surgery
Not yet reported The Cleveland Clinic 120 participants Est. completion 2029-12-31 22 sitesMASLDMASH Other conditions: Non-Alcoholic Fatty Liver Disease, Liver Fibrosis, ObesityView official trial listing → -
Recruiting NCT NCT06380426
A Multicenter Pharmacoepidemiological Cohort on Real Life Use of Semaglutide in Adolescents or Adults With Monogenic Obesity
Assistance Publique - Hôpitaux de Paris 175 participants Est. completion 2027-11-30 2 sitesOther conditions: Monogenic ObesityView official trial listing → -
Recruiting NCT NCT06387199
Alleviating Carbohydrate Counting for Patients with Type-1 Diabetes Using a Closed Loop System with Weekly Subcutaneous Semaglutide
Not yet reported, Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 26 participants Est. completion 2027-01 1 site Stand-aloneOther conditions: Type 1 Diabetes, Diabetes MellitusView official trial listing → -
Recruiting NCT NCT06396416
Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2
Not yet reported Western University, Canada 60 participants Est. completion 2026-12 1 site Stand-aloneChronic kidney disease Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT06411210
Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment
Not yet reported Yale University 54 participants Est. completion 2028-06-30 1 siteOther conditions: Diabetes type1, ObesityView official trial listing → -
Recruiting NCT NCT06423599
Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure
Not yet reported, Not yet reported Jens D Hove, MD,PHD 100 participants Est. completion 2027-12-30 1 site Stand-aloneHeart failure Other conditions: Obesity, Weight LossView official trial listing → -
Recruiting NCT NCT06431308
Nutritional Therapy to Incretin-based Anti-obesity Medications in the Management of Gastrointestinal Adverse Events
Not yet reported Ariel University 120 participants Est. completion 2026-03-30 3 sitesOther conditions: Obesity; DrugView official trial listing → -
Recruiting NCT NCT06446531
Prevention of Progression of Prediabetes, Obesity and CV Risk
Not yet reported The University of Texas Health Science Center at San Antonio 64 participants Est. completion 2027-07 1 sitePrediabetesCardiovascular disease Other conditions: Weight, BodyView official trial listing → -
Recruiting NCT NCT06461377
The Ameliorative Effects of GLP-1RA on Diabetic Cardiac Autonomatic Neuropathy
Not yet reported The First Affiliated Hospital with Nanjing Medical University 50 participants Est. completion 2027-12-31 1 siteType 2 diabetes Other conditions: Diabetes With Diabetic Autonomic Neuropathy (Diagnosis)View official trial listing → -
Recruiting NCT NCT06487832
Effect of GLP1 Receptor Agonist on Brain Insulin Responsiveness
Not yet reported University Hospital Tuebingen 60 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Normal Weight, Overweight and Obesity, Insulin Sensitivity, Insulin ResistanceView official trial listing → -
Recruiting NCT NCT06497595
Lifestyle Intervention to Reduce the Risk of Sarcopenia in Adults With Diabetes & Obesity Treated With Semaglutide
Not yet reported Sheba Medical Center 60 participants Est. completion 2027-11-30 2 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT06499857
Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation
Not yet reported University of Chicago 200 participants Est. completion 2028-06 2 sitesOther conditions: Overweight or Obesity, Atrial FibrillationView official trial listing → -
Recruiting NCT NCT06548490
GLP-1R Agonist Treatment for Opioid Use Disorder
Not yet reported Milton S. Hershey Medical Center 200 participants Est. completion 2027-04-30 4 sitesSubstance use disorder Other conditions: Opioid Abuse and Addiction, Narcotic-Related Disorders, Chemically-Induced Disorders, Mental Disorder, OpioidView official trial listing → -
Recruiting NCT NCT06575738
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
Not yet reported University of Colorado, Denver 40 participants Est. completion 2027-10-01 1 siteOther conditions: Obesity, Adolescent Obesity, Body-Weight Trajectory, Weight Loss Trajectory, Bariatric Surgery, Anti-obesity AgentsView official trial listing → -
Recruiting NCT NCT06613854
Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in Individuals With Type 2 Diabetes
Not yet reported University Medical Centre Ljubljana 90 participants Est. completion 2027-12 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06639464
Semaglutide for Helping Opioid Recovery
Not yet reported Brigham and Women's Hospital 46 participants Est. completion 2026-08-31 1 site Stand-aloneSubstance use disorderView official trial listing → -
Recruiting NCT NCT06686134
Comprehensive Clinical Evaluation Study of GLP-1RA
LI YAN 492 participants Est. completion 2026-07-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06706284
Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes
Not yet reported Marzieh Salehi 50 participants Est. completion 2029-03-01 2 sites Stand-aloneType 2 diabetes Other conditions: Spinal Cord InjuriesView official trial listing → -
Recruiting NCT NCT06717698
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
Not yet reported Novo Nordisk A/S 465 participants Est. completion 2026-09-17 147 sitesChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT06734312
MAINTAIN (Mucosal AblatIoN Therapy After INcretins)
Not yet reported Dr. Christopher McGowan 20 participants Est. completion 2026-06 2 sitesOther conditions: Obesity and Obesity-related Medical Conditions, Obesity and Overweight, Obesity Prevention, Obesity Recidivism, GLP-1, Ablation TechniquesView official trial listing → -
Recruiting NCT NCT06751589
A Study of a Weight Loss Intervention in People With Endometrial Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 36 participants Est. completion 2027-12 7 sites Added to GLP-1Other conditions: Endometrial CancerView official trial listing → -
Recruiting NCT NCT06790160
Study of Patients Being Treated With Anti-obesity Medication
Texas Tech University 100 participants Est. completion 2027-12 1 siteOther conditions: Obesity and OverweightView official trial listing → -
Recruiting NCT NCT06792422
A Study Investigating Oral Semaglutide in People with Open-Angle Glaucoma
Not yet reported Glostrup University Hospital, Copenhagen 126 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Primary Open Angle Glaucoma (POAG), Open-Angle Glaucoma, GlaucomaView official trial listing → -
Recruiting NCT NCT06821919
Impact of Antiglycemic & Immunosuppressive Therapies on NETosis in Diabetes & Kidney Disease (NETs - Neutrophil Traps)
Western Galilee Hospital-Nahariya 70 participants Est. completion 2031-12-30 1 siteOther conditions: Diabetes Mellitus, Kidney DiseaseView official trial listing → -
Recruiting NCT NCT06830343
The Safety, Tolerability, and Pharmacokinetics of of SYH9017 in Chinese Participants With Overweight and Obesity
Not yet reported CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. 66 participants Est. completion 2026-10-01 1 siteOther conditions: Overweight or ObesityView official trial listing → -
Recruiting NCT NCT06852391
JOULE - Metabolic Adaptation to Weight Loss in Response to a Behavioural Lifestyle Program With or Without Semaglutide in Adolescents With Obesity
Not yet reported McMaster University 74 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Obesity (Disorder)View official trial listing → -
Recruiting NCT NCT06856291
Response to Semaglutide in Non-diabetic Obese Patients With Varying Degrees of Insulin Resistance
ETH Zurich 40 participants Est. completion 2026-08-31 1 siteOther conditions: Obesity and Obesity-related Medical Conditions, Obesity and Overweight, Insulin Sensitivity/Resistance, SemaglutideView official trial listing → -
Recruiting NCT NCT06885736
LEAN Mass Preservation With Resistance Exercise and Protein During Semaglutide/Tirzepatide Therapy
Not yet reported Dasman Diabetes Institute 232 participants Est. completion 2029-12-31 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT06894784
A Clinical Trial to Evaluate The Effects of Semaglutide and Empagliflozin Combined to Automated Insulin Delivery on Diabetes Control in Adults Living With Type 1 Diabetes
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 36 participants Est. completion 2027-01 1 site Stand-aloneOther conditions: Diabetes Type 1View official trial listing → -
Recruiting NCT NCT06896981
Semaglutide in Women With Polycystic Ovary Syndrome and Obesity
Not yet reported, Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 30 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome (PCOS) Women, ObesityView official trial listing → -
Recruiting NCT NCT06897475
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Not yet reported Eli Lilly and Company 240 participants Est. completion 2027-01 60 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT06903923
Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy
Not yet reported University of Virginia 120 participants Est. completion 2030-04-30 1 siteOther conditions: Obesity in Children, Bone Strength, GLP - 1, Lifestyle Modification, Bone Density, ObesityView official trial listing → -
Recruiting NCT NCT06908694
Investigation of GLP1-Receptor Agonists in Men With Prostate Cancer Taking Androgen Deprivation Therapy
Not yet reported Hamilton Health Sciences Corporation 20 participants Est. completion 2026-07-31 1 siteOther conditions: Prostate CancerView official trial listing → -
Recruiting NCT NCT06934655
Early Reinitiation of Semaglutide Post-Sleeve Gastrectomy in Youth
Not yet reported Children's Hospital Los Angeles 150 participants Est. completion 2033-11-01 1 siteOther conditions: Pediatric Obesity, Metabolic and Bariatric Surgery, SemaglutideView official trial listing → -
Recruiting NCT NCT06937060
Effect of Semaglutide in Patients With Psoriasis and Obesity
Not yet reported The University of Hong Kong 14 participants Est. completion 2027-01-31 1 siteOther conditions: Psoriasis (PsO), Obesity and OverweightView official trial listing → -
Recruiting NCT NCT06967389
Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity
John Bauer 50 participants Est. completion 2028-07 1 siteCardiovascular disease Other conditions: Obesity and Overweight, Obese Adolescents, Weight Management, Weight LossView official trial listing → -
Recruiting NCT NCT06975111
Focusing on the Menopausal Transition to Improve Mid-Life Women's Health
Not yet reported, Not yet reported University of Colorado, Denver 200 participants Est. completion 2030-10-01 3 sitesOther conditions: Menopause, Menopause Hot Flashes, Menopause Related Conditions, CardiovascularView official trial listing → -
Recruiting NCT NCT06986993
Impact of Semaglutide on Tobacco Use and Related Health Behaviors
Not yet reported University of Oklahoma 40 participants Est. completion 2028-06-30 1 siteOther conditions: Tobacco UseView official trial listing → -
Recruiting NCT NCT06989177
Probiotic Intervention on Body Weight
Not yet reported Chinese Academy of Sciences 140 participants Est. completion 2026-12-31 1 siteOther conditions: Obesity, Homeostasis, Weight Loss, Probiotic InterventionView official trial listing → -
Recruiting NCT NCT06989203
Protein Supplementation Intervention on Body Weight
Not yet reported Chinese Academy of Sciences 140 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Obesity, Weight Loss, Protein SupplementationView official trial listing → -
Recruiting NCT NCT07010432
The Role of the Amylin Analogue Cagrilintide in Bone Metabolism
Not yet reported Novo Nordisk A/S 144 participants Est. completion 2028-05-03 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07036172
Efficacy and Safety of Semaglutide Injection Vs WEGOVY® in Chinese Obese Patients
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 460 participants Est. completion 2026-05 1 siteOther conditions: Obesity ControlView official trial listing → -
Recruiting NCT NCT07040592
Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 3 Semaglutide
Not yet reported Yale University 30 participants Est. completion 2027-06-30 1 site Stand-aloneAlcohol use disorder Other conditions: HIVView official trial listing → -
Recruiting NCT NCT07042672
Behavioral Therapy and GLP-1 Analogue Effects on Binge Eating, Weight, and Coping in Obesity
Haukeland University Hospital 80 participants Est. completion 2028-12-31 1 siteOther conditions: Binge Eating Disorder Associated With Obesity, Binge Eating Disorder, Eating Disorder Binge, Eating Disorders, GLP-1, CBT, Obesity &Amp; OverweightView official trial listing → -
Recruiting NCT NCT07058155
Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease
Not yet reported The Cleveland Clinic 70 participants Est. completion 2034-02-01 1 siteOther conditions: Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPSView official trial listing → -
Recruiting NCT NCT07059377
Semaglutide for Smoking Cessation in Patients With Diabetes
Not yet reported Ottawa Heart Institute Research Corporation 100 participants Est. completion 2027-07 1 siteType 2 diabetes Other conditions: Nicotine Addiction, Tobacco DependenceView official trial listing → -
Recruiting NCT NCT07064486
A Study of BGM0504 in Participants With Type 2 Diabetes in Indonesia
Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 477 participants Est. completion 2026-07-31 4 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT07065383
Rebalancing the Fat Content of the Heart and Muscles
Not yet reported University of Aberdeen 60 participants Est. completion 2028-07-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07091500
Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With Obesity
Not yet reported Washington University School of Medicine 40 participants Est. completion 2029-08-01 1 site Added to GLP-1Other conditions: Obesity, Skeletal Muscle, Brain ConnectivityView official trial listing → -
Recruiting NCT NCT07092618
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation
Not yet reported, Not yet reported AgelessRx 150 participants Est. completion 2025-08 1 site Stand-aloneOther conditions: Longevity, GLP-1, Geroscience, AgingView official trial listing → -
Recruiting NCT NCT07101939
A Study of the Effect of (S)-Pindolol Benzoate (ACM-001.1) on Lean Body Mass (LBM) in Obese Patents During (PROACT 1), and Post-semaglutide Therapy (PROACT 2)
Not yet reported Actimed Therapeutics Ltd 120 participants Est. completion 2027-03 7 sitesOther conditions: Obesity, Muscle LossView official trial listing → -
Recruiting NCT NCT07107334
A Study to Estimate Early Clinical Efficacy Signals of GLP-1 Agonist Administration in Conjunction With Levonorgestrel Intrauterine Device in Obese Patients With Endometrioid Intraepithelial Neoplasia
Not yet reported University of Florida 20 participants Est. completion 2029-11 1 site Stand-aloneOther conditions: Endometrioid Endometrial AdenocarcinomaView official trial listing → -
Recruiting NCT NCT07136714
Does Semaglutide Improve Depressive Symptoms in Patients With Major Depressive Disorder and Overweight or Obesity
Not yet reported Nordsjaellands Hospital 116 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: Major Depressive DisorderView official trial listing → -
Recruiting NCT NCT07150975
Phase III Clinical Study Comparing the Efficacy and Safety of GZR18 Injection and Semaglutide (Wegovy®) in Adult Obese or Overweight Subjects
Not yet reported Gan & Lee Pharmaceuticals. 420 participants Est. completion 2027-06-30 1 siteOther conditions: Obesity/Overweight in AdultView official trial listing → -
Recruiting NCT NCT07169136
Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)
Nemours Children's Clinic 20 participants Est. completion 2026-12 1 siteOther conditions: Polycystic Ovarian Syndrome in Adolescent Females, Obesity (Disorder)View official trial listing → -
Recruiting NCT NCT07171723
Studying the Influence of LEAP2 on Integrated Endocrine Control of Eating During Semaglutide Treatment
Not yet reported, Not yet reported University Hospital, Gentofte, Copenhagen 24 participants Est. completion 2026-02-01 1 site Stand-aloneOther conditions: Obesity &Amp; OverweightView official trial listing → -
Recruiting NCT NCT07178145
Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction
Not yet reported University of Virginia 192 participants Est. completion 2029-12 1 siteHeart failure Other conditions: Epicardial Adipose TissueView official trial listing → -
Recruiting NCT NCT07195994
A Clinical Trial to Examine the Efficacy and Safety of an Investigational Product With and Without Use of Semaglutide on Glycemic Response in Adults With Prediabetes or Type 2 Diabetes
Not yet reported QuickSilver Scientific 90 participants Est. completion 2026-09 1 siteType 2 diabetesPrediabetesView official trial listing → -
Recruiting NCT NCT07204249
Glutide for Ending Methamphetamine
Not yet reported San Francisco Department of Public Health 162 participants Est. completion 2030-02-15 1 site Stand-aloneOther conditions: Methamphetamine-dependenceView official trial listing → -
Recruiting NCT NCT07207148
People With Multiple Sclerosis Treated With Ocrelizumab and GLP-1 Agonists
Northwestern University 100 participants Est. completion 2028-08-31 1 siteOther conditions: Multiple SclerosisView official trial listing → -
Recruiting NCT NCT07213323
Probiotic Intervention for Digestive Health in Obese Patients Initiating GLP-RA Treatment
Not yet reported Hospices Civils de Lyon 50 participants Est. completion 2028-08-05 1 site Stand-aloneOther conditions: Obesity &Amp; Overweight, Digestive DisordersView official trial listing → -
Recruiting NCT NCT07213466
Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder
Not yet reported Mayo Clinic 100 participants Est. completion 2029-02-01 1 site Stand-aloneOther conditions: Bipolar I Disorder, Bipolar II Disorder, Schizo Affective Disorder, Obesity, Weight Loss, GLP - 1View official trial listing → -
Recruiting NCT NCT07218354
Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)
Not yet reported VA Office of Research and Development 622 participants Est. completion 2030-03-30 19 sites Stand-aloneAlcohol use disorderView official trial listing → -
Recruiting NCT NCT07221214
GLP-1 Receptor Agonists to Decrease Ethanol and CVD Risk in HIV
Not yet reported Vanderbilt University Medical Center 200 participants Est. completion 2030-01-31 1 siteCardiovascular disease Other conditions: HIV, Alcohol, Smoking CigaretteView official trial listing → -
Recruiting NCT NCT07223242
Tailored Exercise Training Study Among Adults With HFpEF
Not yet reported, Not yet reported University of Texas Southwestern Medical Center 120 participants Est. completion 2026-12-30 1 site Stand-aloneHeart failure Other conditions: Diabetic CardiomyopathiesView official trial listing → -
Recruiting NCT NCT07223983
Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)
Not yet reported Yale University 10 participants Est. completion 2026-10-31 1 siteAlcohol use disorder Other conditions: Weight Loss, Bariatric Surgery PatientsView official trial listing → -
Recruiting NCT NCT07225816
Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)
Not yet reported Novo Nordisk A/S 71 participants Est. completion 2027-01-06 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07229170
Changes in Taste and Eating Habits Associated With GLP-1 Agonists in Weight Loss Patients
San Raffaele Telematic University 150 participants Est. completion 2028-01-01 4 sites Stand-aloneOther conditions: Obesity & Overweight, Taste Alterations, Weight Loss, Eating Behavior ChangesView official trial listing → -
Recruiting NCT NCT07239570
A Biomarker-targeted Clinical Trial to Optimize Treatment for Patients With Chronic Kidney Disease
Not yet reported Peter Rossing 125 participants Est. completion 2028-06 4 sites Stand-aloneChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT07242534
Effect of Semaglutide on Embryo Quality in Overweight and Obese Patients Undergoing In Vitro Fertilization.
Not yet reported Fundacion Dexeus 62 participants Est. completion 2027-05 5 sites Stand-aloneOther conditions: Infertility, ObesityView official trial listing → -
Recruiting NCT NCT07253285
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
Not yet reported Novo Nordisk A/S 460 participants Est. completion 2033-09-20 121 sitesOther conditions: Overweight, ObesityView official trial listing → -
Recruiting NCT NCT07254572
Anti-atherosclerotic Efficacy of Selected Antidiabetic Drugs in Patients With Coronary Artery Disease and Pre-diabetes
Not yet reported National Institute of Cardiology, Warsaw, Poland 300 participants Est. completion 2029-08-01 1 site Stand-aloneCardiovascular diseasePrediabetesView official trial listing → -
Recruiting NCT NCT07254715
Effect of Itopride on Semaglutide Gastroparesis
Not yet reported Ain Shams University 60 participants Est. completion 2026-04 1 siteOther conditions: Semaglutide-Induced Gastric Motility, AnesthesiaView official trial listing → -
Recruiting NCT NCT07272343
The Impact of Semaglutide Compared to Energy Restriction on Type 2 Diabetes
Not yet reported Second Affiliated Hospital of Nanchang University 100 participants Est. completion 2026-07-01 1 siteType 2 diabetes Other conditions: Semaglutide, Caloric RestrictionView official trial listing → -
Recruiting NCT NCT07272837
Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass
University of Alberta 50 participants Est. completion 2028-04-30 1 siteType 2 diabetes Other conditions: Obesity, Semaglutide, GLP-1, DiabetesView official trial listing → -
Recruiting NCT NCT07275697
Waiting on Atrial Fibrillation Intervention Therapy (WAIT) Study
Not yet reported Emma Svennberg 200 participants Est. completion 2028-12-30 1 siteOther conditions: Atrial Fibrillation (AF), Obesity & OverweightView official trial listing → -
Recruiting NCT NCT07282613
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 80 participants Est. completion 2030-03-30 58 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07284979
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
Not yet reported Kailera 1200 participants Est. completion 2028-04 59 sitesOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07293325
Semaglutide and Tirzepatide for Genetic Aging Delay in Adults With Obesity
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 66 participants Est. completion 2027-06-02 1 site Stand-aloneOther conditions: Adults With Simple ObesityView official trial listing → -
Recruiting NCT NCT07294950
Impact of Semaglutide Withdrawal on Cardiometabolic Profile and Physiology of Energy Balance: Recovery Effects After Semaglutide Termination
Not yet reported Mount Sinai Hospital, Canada 98 participants Est. completion 2029-05 1 siteOther conditions: Obesity (Disorder), Weight Change, Blood Pressure Monitoring, Appetite RegulationView official trial listing → -
Recruiting NCT NCT07295223
Effect of Glp-1 and Antidiabetic sgLT2 Agents for myoCardial infarcTion and Ultrasensitive Inflammatory Surveillance (GALACTUS Trial)
Not yet reported Instituto Mexicano del Seguro Social 44 participants Est. completion 2026-09 1 siteCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT07297589
Epicardial Cardiac Fat-CT (EPIC-CT)
Not yet reported Instituto Mexicano del Seguro Social 136 participants Est. completion 2027-03 1 siteCardiovascular disease Other conditions: Epicardial FatView official trial listing → -
Recruiting NCT NCT07302802
Efficacy of Semaglutide s.c. Once-weekly on Weight Loss and Management in Adolescents With Monogenic Obesity in Clinical Practice
Prof. Dr. Martin Wabitsch 70 participants Est. completion 2028-12 7 sitesOther conditions: Monogenic ObesityView official trial listing → -
Recruiting NCT NCT07309094
Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD
Cardenal Herrera University 250 participants Est. completion 2028-12-31 1 siteChronic kidney diseaseType 2 diabetes Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT07314684
GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM
Not yet reported Federico II University 80 participants Est. completion 2027-03-08 2 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT07317115
Side-to-Side Duodeno-ileostomy Versus Semaglutide in Adults With Obesity and Type 2 Diabetes
Not yet reported GT Metabolic Solutions, Inc. 20 participants Est. completion 2028-06 1 siteType 2 diabetes Other conditions: Obesity (Disorder), Obesity & OverweightView official trial listing → -
Recruiting NCT NCT07325500
Incretin Microdosing for Cardiometabolic Health in People With HIV
Not yet reported The University of Texas Health Science Center, Houston 30 participants Est. completion 2029-06-30 1 site Stand-aloneOther conditions: Weight GainView official trial listing → -
Recruiting NCT NCT07336862
Bariatric Surgery Combined With GLP-1 Receptor Agonists Study
Not yet reported, Not yet reported China-Japan Friendship Hospital 200 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07361874
IMPACT-MACS: Adrenalectomy vs Semaglutide for Metabolic Outcomes in Mild Autonomous Cortisol Secretion
Not yet reported University of Texas Southwestern Medical Center 75 participants Est. completion 2030-05-31 1 siteOther conditions: Mild Autonomous Cortisol Secretion (MACS), Autonomous Cortisol Secretion (ACS), Subclinical Cushing's, Mild Autonomous Cortisol ExcessView official trial listing → -
Recruiting NCT NCT07374328
Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Second Affiliated Hospital of Guangzhou Medical University 240 participants Est. completion 2026-08-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07401992
Effects of Semaglutide on Clinical Outcomes and Metabolic Inflammation in Psoriasis
Not yet reported Hospital Universitario Dr. Jose E. Gonzalez 62 participants Est. completion 2027-02-28 1 siteOther conditions: Psoriasis (PsO), Obesity & Overweight, Diabetes Mellitus - Type 2View official trial listing → -
Recruiting NCT NCT07415954
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 270 participants Est. completion 2027-10-01 63 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT07428746
Investigating the Impact of GLP-1 RA Therapy on Osteosarcopenia in Older Female Adults With Diabetes
Not yet reported Emory University 20 participants Est. completion 2028-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07446439
A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use
Not yet reported Vanda Pharmaceuticals 280 participants Est. completion 2026-12-01 10 sitesOther conditions: Nausea and Vomiting, ObesityView official trial listing → -
Recruiting NCT NCT07465965
A Clinical Study of Semaglutide Nasal Spray in Overweight or Obese Adults
Not yet reported Shanghai World Leader Pharmaceutical Co., Ltd. 60 participants Est. completion 2026-08-30 1 site Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Recruiting NCT NCT07502508
Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy
Not yet reported Biomea Fusion Inc. 60 participants Est. completion 2027-07 17 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07513168
Low-Dose Semaglutide for Weight Loss in Obese Non-Diabetic Pakistani Adults
Not yet reported Asian Institute Of Medical Sciences 60 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: Obesity, Weight Reduction, Cardiometabolic Risk FactorsView official trial listing → -
Recruiting NCT NCT07527195
Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscle Health)
Not yet reported Novo Nordisk A/S 100 participants Est. completion 2028-06-09 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07539415
A Phase 1 Clinical Trial to Assess the Safety of DWRX5003 and Relative Bioavailability to DWC202502 and DWC202503 in Healthy Adult Volunteers
Not yet reported Daewoong Pharmaceutical Co. LTD. 72 participants Est. completion 2026-11-17 1 siteType 2 diabetes Other conditions: Obesity & OverweightView official trial listing → -
Recruiting NCT NCT07558863
Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes
Not yet reported The First Affiliated Hospital with Nanjing Medical University 60 participants Est. completion 2028-08-30 1 siteType 2 diabetes Other conditions: Diabetes With Diabetic Autonomic Neuropathy (Diagnosis)View official trial listing → -
Recruiting NCT NCT07563699
Safety, Tolerability and Efficacy of Semaglutide Depot in Subjects With Type-2 Diabetes Mellitus
Not yet reported, Not yet reported Mapi Pharma Ltd. 24 participants Est. completion 2028-06 1 siteOther conditions: Diabete Type 2View official trial listing → -
Recruiting NCT NCT07564414
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Not yet reported Novo Nordisk A/S 2500 participants Est. completion 2028-04-19 303 sites Stand-aloneType 2 diabetes Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT07581145
Effect of Semaglutide on Healing of Foot Ulcers in Type 2 Diabetes Patients
Not yet reported Ole Lander Svendsen 52 participants Est. completion 2029-12 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07589322
Comparative Observation of Metabolic and Pharmacologic Adipose Remodeling With Enhanced Incretin AgonisTs
Not yet reported Tri-Service General Hospital (TSGH) 120 participants Est. completion 2029-09-30 1 siteMetabolic syndromeView official trial listing → -
Recruiting NCT NCT07597018
A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or Obesity
Not yet reported Novo Nordisk A/S 234 participants Est. completion 2027-06-01 1 site Stand-aloneOther conditions: Obesity, OverweightView official trial listing → -
Recruiting NCT NCT07605572
Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellitus and Obesity
Attikon Hospital 100 participants Est. completion 2027-02-28 1 siteOther conditions: Dry Eye Disease (DED), Diabete Mellitus, GLP-1, Ocular Surface, Diabetes Type 2, CorneaView official trial listing → -
Recruiting NCT NCT07621419
Study of Adult Patients Residing in Argentina Diagnosed With Type 2 Diabetes Treated With a New Formulation of Semaglutide, Both Oral and Subcutaneous, in a Real-world Setting at 3 Months, 6 Months, and 1 Year of Follow-up, Quantifying the Reduction in Glycated Hemoglobin
Hospital Italiano de Buenos Aires 145 participants Est. completion 2028-12-31 2 sitesOther conditions: Diabetes MellitusView official trial listing → -
Recruiting NCT NCT07633639
GLP-1 Therapy After Bariatric Surgery in Chinese Patients With Obesity
Not yet reported China-Japan Friendship Hospital 200 participants Est. completion 2028-05-01 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07639021
A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity
Not yet reported Novo Nordisk A/S 230 participants Est. completion 2027-07-12 25 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07651319
Interleukine-2 (IL-2) Plus Semaglutide in Alzheimer's Disease
Not yet reported, Not yet reported The Methodist Hospital Research Institute 30 participants Est. completion 2029-12 1 siteOther conditions: Alzheimer Dementia (AD)View official trial listing → -
Recruiting NCT NCT07653412
Precision Obesity Medicine: Genetic Prediction of Response to GLP-1/GIP Agonists.
National and Kapodistrian University of Athens 220 participants Est. completion 2027-06-30 1 siteOther conditions: Obesity (Disorder), Anti-obesity Agents, Precision MedicineView official trial listing → -
Recruiting NCT NCT07662213
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 1200 participants Est. completion 2028-05-23 209 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT07702461
Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor Agonists
Ohio State University 300 participants Est. completion 2027-01 1 siteOther conditions: Obesity & Overweight, Diabetes (DM)View official trial listing → -
Recruiting NCT NCT07720414
Effects of GLP-1 RAs on Human Lactation Outcomes
University of Colorado, Denver 18 participants Est. completion 2028-06 1 siteOther conditions: Lactation, Weight LossView official trial listing → -
Recruiting NCT NCT07728669
Digital Dietary Intervention for Patients Receiving GLP-1 Receptor Agonist Therapy
Not yet reported Kazakh Academy of Nutrition 120 participants Est. completion 2027-01 1 siteType 2 diabetesMetabolic syndrome Other conditions: Obesity (Disorder), OverweightView official trial listing → -
Recruiting NCT NCT07732426
Effects of Semaglutide on Brain Dopamine Responses to Food Cues in Adults With Obesity and Food Addiction Tendencies
Not yet reported Seoul National University Hospital 30 participants Est. completion 2028-06-30 1 site Stand-aloneOther conditions: Food Addiction Tendency, Obesity, OverweightView official trial listing → -
Recruiting NCT NCT07740291
Tirzepatide Impact Assessment Study
Not yet reported Texas Tech University 27 participants Est. completion 2026-12-07 1 siteOther conditions: Obesity & Overweight, Cardiometabolic Health Indicators, Addiction, Eating Disorders, Mental HealthView official trial listing → -
Recruiting NCT NCT07743983
A Study of BGM0504 in Early T2DM With Obesity
Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 372 participants Est. completion 2028-11-30 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07767175
A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity
Not yet reported Novo Nordisk A/S 142 participants Est. completion 2027-09-23 2 sitesOther conditions: Overweight, ObesityView official trial listing → -
Recruiting NCT NCT07770841
Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight
Not yet reported Novo Nordisk A/S 450 participants Est. completion 2028-04-11 62 sites Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Recruiting NCT NCT07779343
OBESIAL: A Prospective Interventional Real-world Study of a Multidisciplinary Obesity Management Programme
Not yet reported University of Health Sciences, Algeria 300 participants Est. completion 2028-01-23 1 site Stand-aloneType 2 diabetes Other conditions: Obesity Difficult Airway Airway Management, Obesity Adult Onset, Obesity and Cardiovascular RiskView official trial listing → -
Recruiting NCT NCT07801820
Phase 2 Clinical Study of MWN109 Tablets in Participants With Type 2 Diabetes Mellitus
Not yet reported Shanghai Minwei Biotechnology Co., Ltd 240 participants Est. completion 2027-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00696657
A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and Liraglutide
Not yet reported Novo Nordisk A/S 415 participants Est. completion 2009-02-05 77 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00813020
A Clinical Trial Investigating the Comparison of Three Different Concentrations of NN9535 in Healthy Male Subjects
Not yet reported Novo Nordisk A/S 44 participants Est. completion 2009-04 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00833716
Effect of Renal Impairment on the Pharmacokinetics of NN9535
Not yet reported Novo Nordisk A/S 62 participants Est. completion 2010-07-26 3 sites Stand-aloneType 2 diabetes Other conditions: Diabetes, Renal ImpairmentView official trial listing → -
Completed NCT NCT00851773
Safety, Tolerability, and Profile of Action of Drug in the Body of NN9535 in Healthy Male Japanese and Caucasian Subjects
Not yet reported Novo Nordisk A/S 84 participants Est. completion 2009-10 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01272973
Investigation on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NN9924 in Healthy Male Subjects
Not yet reported Novo Nordisk A/S 96 participants Est. completion 2011-07 1 site Stand-aloneType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01324505
Effect of Oral Contraceptives After Administration of Semaglutide in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 43 participants Est. completion 2012-01 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Enrolling by invitation NCT NCT01511393
An Active Surveillance Program for Cases of Medullary Thyroid Carcinoma (MTC)
Novo Nordisk A/S 6750 participants Est. completion 2039-12 1 siteType 2 diabetes Other conditions: Diabetes, Medullary Thyroid Carcinoma, Weight ManagementView official trial listing → -
Completed NCT NCT01572753
Investigation of Optimal Dosing Conditions for a Long Acting GLP-1 Analogue in Healthy Male Subjects
Not yet reported Novo Nordisk A/S 161 participants Est. completion 2012-09-08 1 siteType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01619345
Pharmacoscintigraphic Investigation of NN9924 in Healthy Male Subjects
Not yet reported Novo Nordisk A/S 27 participants Est. completion 2012-08 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01686945
Investigation on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses of a Long-acting GLP-1 Analogue in Healthy Male Subjects and Male Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 107 participants Est. completion 2013-04-08 1 siteType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01720446
Trial to Evaluate Cardiovascular and Other Long-term Outcomes With Semaglutide in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 3297 participants Est. completion 2016-03-15 253 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01766245
A Randomised, Single Centre, Double-blind, Two-period, Cross-over Trial in Healthy Subjects Investigating the Bioequivalence Between Subcutaneous Injections of Semaglutide Produced by Two Manufacturing Processes
Not yet reported Novo Nordisk A/S 28 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01866748
Investigation on Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses of a Long-acting GLP-1 Analogue (Semaglutide) in an Oral Formulation in Healthy Male Subjects
Not yet reported Novo Nordisk A/S 170 participants Est. completion 2014-04 1 site Added to GLP-1Type 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01885208
Efficacy and Safety of Semaglutide Once-weekly Versus Exenatide ER 2.0 mg Once-weekly as add-on to 1-2 Oral Antidiabetic Drugs (OADs) in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 813 participants Est. completion 2015-07-13 146 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01923181
Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 632 participants Est. completion 2014-12-11 103 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01930188
Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1231 participants Est. completion 2015-10-12 141 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02014259
Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Various Degrees of Impaired Renal Function
Not yet reported Novo Nordisk A/S 71 participants Est. completion 2014-10-24 4 sitesType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02016911
Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Hepatic Impairment
Not yet reported Novo Nordisk A/S 56 participants Est. completion 2015-01-12 6 sitesType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02022254
Influence of Semaglutide on Pharmacokinetics and Pharmacodynamics of Warfarin and Pharmacokinetics of Metformin in Healthy Subjects
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2014-08-28 1 site Stand-aloneType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02054897
Efficacy and Safety of Semaglutide Once-weekly Versus Placebo in Drug-naïve Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 388 participants Est. completion 2015-05-08 86 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02060266
Trial Investigating the Absorption, Metabolism and Excretion After a Single Subcutaneous Dose of [3H]-Semaglutide in Healthy Male Subjects
Not yet reported Novo Nordisk A/S 7 participants Est. completion 2014-04-28 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02064348
A Thorough QTc Evaluation of the Effect of Semaglutide on Cardiac Repolarisation in Healthy Subjects
Not yet reported Novo Nordisk A/S 168 participants Est. completion 2015-04-23 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02070510
A Trial Investigating the Influence of Oral Semaglutide on the Pharmacokinetics of Lisinopril and Warfarin in Healthy Subjects
Not yet reported Novo Nordisk A/S 52 participants Est. completion 2014-08-20 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02128932
Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1089 participants Est. completion 2015-09-03 231 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02146079
A Trial to Assess the Pharmacokinetics, Pharmacodynamics, and the Safety and Tolerability of Semaglutide in Healthy Male Japanese and Caucasian Subjects
Not yet reported Novo Nordisk A/S 44 participants Est. completion 2014-10-20 1 site Stand-aloneType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02147431
A Trial Investigating the Effect of Semaglutide on Hypoglycaemic Counterregulation Compared to Placebo in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 38 participants Est. completion 2015-05-20 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02161588
A Trial to Assess the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Oral Semaglutide in Healthy Male Japanese and Caucasian Subjects
Not yet reported Novo Nordisk A/S 48 participants Est. completion 2014-11 1 siteType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02172313
Effect of Food on the Pharmacokinetics of Oral Semaglutide in Healthy Subjects
Not yet reported Novo Nordisk A/S 78 participants Est. completion 2014-10 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02207374
A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly in Monotherapy or in Combination With One OAD in Japanese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 601 participants Est. completion 2016-02-27 43 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02210871
Investigating the Pharmacokinetics, Safety and Tolerability After a Single Subcutaneous Injection of Semaglutide in Subjects With Mild, Moderate or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function
Not yet reported Novo Nordisk A/S 44 participants Est. completion 2015-06-03 4 sitesType 2 diabetes Other conditions: Diabetes, Hepatic ImpairedView official trial listing → -
Completed NCT NCT02212067
A Trial Investigating the Effects of Semaglutide on ß-cell Function in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 87 participants Est. completion 2015-05-11 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02231684
Investigating the Pharmacokinetics of Subcutaneous Injections With 1 mg/mL, 3 mg/mL, and 10 mg/mL Semaglutide Strengths and the Absolute Bioavailability of Semaglutide
Not yet reported Novo Nordisk A/S 42 participants Est. completion 2015-01 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02243098
Investigating the Influence of Semaglutide on the Pharmacokinetics of Single Doses of Atorvastatin and Digoxin in Healthy Subjects
Not yet reported Novo Nordisk A/S 31 participants Est. completion 2015-04-07 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02249871
Investigating the Influence of Omeprazole on the Pharmacokinetics of Oral Semaglutide in Healthy Subjects
Not yet reported Novo Nordisk A/S 54 participants Est. completion 2015-04-01 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02249910
Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Metformin and Digoxin in Healthy Subjects
Not yet reported Novo Nordisk A/S 32 participants Est. completion 2015-03-06 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02254291
A Trial Comparing the Safety and Efficacy of Semaglutide Once Weekly Versus Sitagliptin Once Daily in Japanese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 308 participants Est. completion 2015-11-11 25 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02305381
Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to Basal Insulin Alone or Basal Insulin in Combination With Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 397 participants Est. completion 2015-11-21 99 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02453711
Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus
Not yet reported Novo Nordisk A/S 957 participants Est. completion 2017-04-12 74 sites Stand-aloneOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT02461589
Dose-finding of Semaglutide Administered Subcutaneously Once Daily Versus Placebo and Liraglutide in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 706 participants Est. completion 2016-10-13 150 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02557620
Comparing Semaglutide Administered Subcutaneously Once Daily to Semaglutide Administered Subcutaneously Once Weekly
Not yet reported Novo Nordisk A/S 113 participants Est. completion 2016-04 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02607865
Efficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1864 participants Est. completion 2018-03-28 242 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02648204
Efficacy and Safety of Semaglutide Versus Dulaglutide as add-on to Metformin in Subjects With Type 2 Diabetes.
Not yet reported Novo Nordisk A/S 1201 participants Est. completion 2017-05-19 209 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02692716
A Trial Investigating the Cardiovascular Safety of Oral Semaglutide in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 3183 participants Est. completion 2018-09-25 228 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02773381
A Trial Investigating the Effect of Oral Semaglutide Compared With Placebo on Postprandial Glucose and Triglyceride Metabolism, Energy Intake, Appetite Sensations and Gastric Emptying in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 15 participants Est. completion 2018-10-19 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02827708
Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes and Moderate Renal Impairment
Not yet reported Novo Nordisk A/S 324 participants Est. completion 2018-05-15 117 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02845219
A Trial Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Ethinylestradiol and Levonorgestrel in an Oral Contraceptive Combination Drug in Healthy Postmenopausal Females
Not yet reported Novo Nordisk A/S 25 participants Est. completion 2016-12 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02849080
Efficacy and Safety of Oral Semaglutide Using a Flexible Dose Adjustment Based on Clinical Evaluation Versus Sitagliptin in Subjects With Type 2 Diabetes Mellitus.
Not yet reported Novo Nordisk A/S 504 participants Est. completion 2019-03-27 83 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02863328
Efficacy and Safety of Oral Semaglutide Versus Empagliflozin in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 822 participants Est. completion 2018-03-08 106 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02863419
Efficacy and Safety of Oral Semaglutide Versus Liraglutide and Versus Placebo in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 711 participants Est. completion 2018-03-30 108 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02877355
Investigation of the Effect of Upper Gastrointestinal Disease on the Pharmacokinetics of Oral Semaglutide in Subjects With Type 2 Diabetes.
Not yet reported Novo Nordisk A/S 55 participants Est. completion 2017-11-24 2 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02906930
Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Diet and Exercise Only
Not yet reported Novo Nordisk A/S 703 participants Est. completion 2017-12-08 105 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02920385
A Trial Investigating the Influence of Oral Semaglutide on the Pharmacokinetics of Levothyroxine and the Influence of Co-administered Tablets on the Pharmacokinetics of Semaglutide Administered Orally in Healthy Subjects.
Not yet reported Novo Nordisk A/S 45 participants Est. completion 2017-06-16 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02970942
Investigation of Efficacy and Safety of Three Dose Levels of Subcutaneous Semaglutide Once Daily Versus Placebo in Subjects With Non-alcoholic Steatohepatitis.
Not yet reported Novo Nordisk A/S 320 participants Est. completion 2020-03-19 158 sites Stand-aloneOther conditions: Hepatobiliary Disorders, Non-alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT03010475
A Trial Investigating the Effect of Oral Semaglutide on the Pharmacokinetics of Furosemide and Rosuvastatin in Healthy Subjects
Not yet reported Novo Nordisk A/S 41 participants Est. completion 2017-08-09 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT03015220
Safety and Efficacy of Oral Semaglutide Versus Dulaglutide Both in Combination With One OAD (Oral Antidiabetic Drug) in Japanese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 458 participants Est. completion 2018-07-12 34 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03018028
Dose-response, Safety and Efficacy of Oral Semaglutide Versus Placebo and Versus Liraglutide, All as Monotherapy in Japanese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 243 participants Est. completion 2018-08-15 16 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03021187
Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Insulin
Not yet reported Novo Nordisk A/S 731 participants Est. completion 2018-08-22 118 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03061214
Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT)
Not yet reported Novo Nordisk A/S 868 participants Est. completion 2019-04-15 67 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03086330
Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to SGLT-2i in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 302 participants Est. completion 2018-08-06 72 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03144271
Dose Escalation Trial of Single Subcutaneous Doses of NNC 0113-0217 to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Male Subjects
Not yet reported Novo Nordisk A/S 58 participants Est. completion 2007-10-08 1 siteType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT03191396
Research Study Comparing a New Medicine Semaglutide to Liraglutide in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 577 participants Est. completion 2018-08-13 92 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03288740
A Trial to Assess the Pharmacokinetics, Safety and Tolerability of Semaglutide in Healthy Chinese Subjects
Not yet reported Novo Nordisk A/S 36 participants Est. completion 2018-08-07 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03292315
Once Weekly GLP-1 in Persons With Spinal Cord Injury
Not yet reported James J. Peters Veterans Affairs Medical Center 5 participants Est. completion 2023-03-01 1 siteOther conditions: Spinal Cord Injuries, Insulin Resistance, Pre Diabetes, ObesityView official trial listing → -
Completed NCT NCT03357380
A Study on How Semaglutide Works on Early Stages of Scar Tissue in the Liver Assessed by Pictures of the Liver
Not yet reported Novo Nordisk A/S 67 participants Est. completion 2020-03-20 2 sites Stand-aloneOther conditions: Hepatobiliary Disorders, Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT03457012
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Canada, as Part of Local Clinical Practice
Novo Nordisk A/S 462 participants Est. completion 2019-12-19 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03466567
A Trial Investigating the Effect of Probenecid and Ciclosporin on the Concentrations of SNAC in Healthy Subjects
Not yet reported Novo Nordisk A/S 21 participants Est. completion 2018-07-10 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03498001
Effects of GLP-1 Agonists on CArdiac Steatosis Evaluated by Magnetic Resonance Imaging
Not yet reported Centre Hospitalier Universitaire Dijon 42 participants Est. completion 2023-12-20 1 site Stand-aloneOther conditions: Type II DiabetesView official trial listing → -
Completed NCT NCT03548935
STEP 1: Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
Not yet reported Novo Nordisk A/S 1961 participants Est. completion 2021-03-05 128 sitesOther conditions: Metabolism and Nutrition Disorder, Overweight or ObesityView official trial listing → -
Completed NCT NCT03548987
Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
Not yet reported Novo Nordisk A/S 902 participants Est. completion 2020-03-20 72 sites Stand-aloneOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT03552757
Research Study Investigating How Well Semaglutide Works in People With Type 2 Diabetes Suffering From Overweight or Obesity
Not yet reported Novo Nordisk A/S 1210 participants Est. completion 2020-05-01 147 sites Stand-aloneOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT03574584
A Research Study of NNC0165-1562 and Semaglutide in People Who Are Overweight or Obese
Not yet reported Novo Nordisk A/S 37 participants Est. completion 2019-07-27 2 sites Stand-aloneOther conditions: Metabolism and Nutrition Disorders, Overweight or ObesityView official trial listing → -
Completed NCT NCT03574597
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity
Not yet reported Novo Nordisk A/S 17604 participants Est. completion 2023-06-29 833 sites Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT03596450
Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial
Not yet reported Novo Nordisk A/S 1278 participants Est. completion 2023-06-09 122 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03598621
A Research Study to Look at Similarity Between Semaglutide Versions in Different Injection Tools
Not yet reported Novo Nordisk A/S 68 participants Est. completion 2019-01-17 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03600480
A Research Study of How NNC0174-0833 Taken With Semaglutide Works in People Who Are Overweight or Obese
Not yet reported Novo Nordisk A/S 96 participants Est. completion 2020-06-12 1 site Stand-aloneOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT03611322
A Trial to Compare Blood Concentration Levels of Semaglutide Following Subcutaneous Injections of Semaglutide 1 mg by 2 Different Devices (the DV3372 Device and by the PDS290 Semaglutide Pen-injector)
Not yet reported Novo Nordisk A/S 54 participants Est. completion 2019-01-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03611582
Research Study to Look at How Well Semaglutide is at Lowering Weight When Taken Together With an Intensive Lifestyle Program
Not yet reported Novo Nordisk A/S 611 participants Est. completion 2020-04-28 41 sitesOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT03631186
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Switzerland, as Part of Local Clinical Practice (SURE SWITZERLAND)
Novo Nordisk A/S 215 participants Est. completion 2019-12-18 28 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03638778
Research Study Comparing Different Tablets With the Study Medicine Semaglutide in Healthy Men
Not yet reported Novo Nordisk A/S 105 participants Est. completion 2018-12-05 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT03648281
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Denmark and Sweden, as Part of Local Clinical Practice (SURE DENMARK/SWEDEN)
Novo Nordisk A/S 333 participants Est. completion 2020-01-10 30 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03689374
A Research Study to Compare Semaglutide to Insulin Aspart, When Taken Together With Metformin and Insulin Glargine, in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 2274 participants Est. completion 2021-02-22 210 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03693430
Two-year Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
Not yet reported Novo Nordisk A/S 304 participants Est. completion 2021-03-23 41 sitesOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT03707990
A Research Study of NNC0165-1875 Alone or Together With Semaglutide in People Who Are Overweight or Obese
Not yet reported Novo Nordisk A/S 88 participants Est. completion 2019-08-13 1 site Stand-aloneOther conditions: Obesity and OverweightView official trial listing → -
Completed NCT NCT03789578
A Research Study to Look at How Insulin 287 and Semaglutide Work in the Body of People With Type 2 Diabetes When Taken Alone or Together
Not yet reported Novo Nordisk A/S 30 participants Est. completion 2019-10-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT03811561
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1500 participants Est. completion 2027-11-07 230 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03811574
STEP 6: Research Study Investigating How Well Semaglutide Works in People Living With Overweight or Obesity
Not yet reported Novo Nordisk A/S 401 participants Est. completion 2020-11-20 28 sites Added to GLP-1Other conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT03842202
A Research Study to Look at How Semaglutide Affects Gastric Emptying in People With Obesity
Not yet reported Novo Nordisk A/S 72 participants Est. completion 2019-11-04 1 site Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT03876015
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in United Kingdom, as Part of Local Clinical Practice (SURE UK)
Novo Nordisk A/S 215 participants Est. completion 2020-08-12 31 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT03899402
Triple Therapy in T1DM
Not yet reported, Not yet reported State University of New York at Buffalo 78 participants Est. completion 2026-06-30 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03914326
A Heart Disease Study of Semaglutide in Patients With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 9651 participants Est. completion 2024-08-23 492 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03919929
Treating PCOS With Semaglutide vs Active Lifestyle Intervention
Not yet reported, Not yet reported University of Colorado, Denver 60 participants Est. completion 2023-10-03 1 siteMASLD Other conditions: PCOS, Adolescent ObesityView official trial listing → -
Completed NCT NCT03929679
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in The Netherlands, as Part of Local Clinical Practice (SURE NETHERLANDS)
Novo Nordisk A/S 218 participants Est. completion 2020-11-24 27 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03951753
A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Eli Lilly and Company 117 participants Est. completion 2021-04-08 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03985384
Semaglutide Treatment On Coronary Progression
Not yet reported Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 140 participants Est. completion 2022-12-27 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT03987451
A Research Study on How Semaglutide Works in People With Fatty Liver Disease and Liver Damage
Not yet reported Novo Nordisk A/S 71 participants Est. completion 2021-06-10 38 sites Stand-aloneOther conditions: Non-alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT03987919
A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 1879 participants Est. completion 2021-02-15 127 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03989232
A Research Study to Compare Two Doses of Semaglutide Taken Once Weekly in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 961 participants Est. completion 2020-11-09 129 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04007107
A Study Comparing the Injection Site Pain Experience After the Injection of 2 Different Solutions of Semaglutide With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and Obesity
Not yet reported Novo Nordisk A/S 103 participants Est. completion 2019-09-04 1 siteType 2 diabetes Other conditions: Healthy Volunteers Overweight, Healthy Volunteers ObesityView official trial listing → -
Terminated NCT NCT04012255
A Research Study to Compare Two Forms of Semaglutide in Two Different Pen-injectors in People With Overweight or Obesity
Not yet reported Novo Nordisk A/S 29 participants Est. completion 2019-10-22 2 sitesOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT04016974
A Research Study of How Oral Semaglutide Tablets Work in Healthy People Who Are Chinese
Not yet reported Novo Nordisk A/S 32 participants Est. completion 2021-02-26 1 site Added to GLP-1Type 2 diabetes Other conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT04017832
A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1441 participants Est. completion 2021-10-27 93 sites Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04019197
Effects of Semaglutide in HIV-Associated Lipohypertrophy
Not yet reported Case Western Reserve University 108 participants Est. completion 2026-09-01 2 sites Stand-aloneOther conditions: HIV/AIDS, Lipohypertrophy, ObesityView official trial listing → -
Completed NCT NCT04032197
A Research Study of How Semaglutide Works in People With Disease Affecting the Heart and/or Blood Vessels and Type 2 Diabetes
Not yet reported Novo Nordisk A/S 101 participants Est. completion 2023-06-06 4 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT04061200
Renal Effects of Treatment With Empagliflozin Alone or in Combination With Semaglutide in Patients With Type 2 Diabetes and Albuminuria
Not yet reported Steno Diabetes Center Copenhagen 80 participants Est. completion 2021-08-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04067999
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Spain, as Part of Local Clinical Practice
Novo Nordisk A/S 230 participants Est. completion 2021-07-19 16 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04074161
Research Study to Investigate How Well Semaglutide Works Compared to Liraglutide in People Living With Overweight or Obesity
Not yet reported Novo Nordisk A/S 338 participants Est. completion 2021-05-11 19 sites Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT04083820
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in France, as Part of Local Clinical Practice (SURE FRANCE)
Novo Nordisk A/S 521 participants Est. completion 2021-09-27 53 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04094415
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Italy, as Part of Local Clinical Practice
Novo Nordisk A/S 581 participants Est. completion 2021-07-28 39 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04097600
A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (D) Semaglutide Tablets
Not yet reported Novo Nordisk A/S 274 participants Est. completion 2021-01-20 1 site Stand-aloneType 2 diabetes Other conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT04102189
A Research Study on How Well Semaglutide Works in Adolescents With Overweight or Obesity
Not yet reported Novo Nordisk A/S 201 participants Est. completion 2022-03-28 51 sites Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT04109508
A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (C) Semaglutide Tablets
Not yet reported Novo Nordisk A/S 278 participants Est. completion 2021-01-27 1 siteType 2 diabetes Other conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT04109547
A Research Study Comparing a New Medicine Oral Semaglutide to Placebo in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 521 participants Est. completion 2021-10-27 66 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04126603
Impact of Semaglutide on CD34+ EPC and Fat Derived MSC
Not yet reported Sabyasachi Sen 10 participants Est. completion 2025-05-14 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04143945
A Study Comparing the Injection Site Pain Experience After the Injection of Semaglutide B and Semaglutide D With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and Obesity
Not yet reported Novo Nordisk A/S 104 participants Est. completion 2020-01-04 1 siteType 2 diabetes Other conditions: Healthy Volunteers Overweight, Healthy Volunteers ObesityView official trial listing → -
Completed NCT NCT04152915
A Research Study Looking at Similarity Between Once-weekly Semaglutide Versions for Different Injection Pens
Not yet reported Novo Nordisk A/S 68 participants Est. completion 2020-05-25 1 siteType 2 diabetes Other conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT04153929
A Study to Test Whether Different Doses of BI 456906 Are Effective in Treating Adults With Type 2 Diabetes.
Not yet reported Boehringer Ingelheim 413 participants Est. completion 2021-11-04 80 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04175665
Real-world Health Outcomes in Canadian Patients Using Semaglutide
LMC Diabetes & Endocrinology Ltd. 1133 participants Est. completion 2020-02-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04189848
Comparison of Injection Site Pain Experience for Semaglutide and Dulaglutide sc
Not yet reported Novo Nordisk A/S 104 participants Est. completion 2020-02-27 1 site Added to GLP-1Type 2 diabetes Other conditions: Healthy Volunteers, Overweight, ObesityView official trial listing → -
Completed NCT NCT04200625
Semaglutide vs Dulaglutide on Epicardial Adipose Tissue
University of Miami 80 participants Est. completion 2019-12-09 1 siteOther conditions: Epicardial FatView official trial listing → -
Completed NCT NCT04216589
Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study)
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 51 participants Est. completion 2023-09-15 9 sites Stand-aloneOther conditions: HIV Infections, Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT04228354
A Research Study Looking at the Comparability (Bioequivalence) of Two Versions of Semaglutide
Not yet reported Novo Nordisk A/S 28 participants Est. completion 2020-06-01 1 siteOther conditions: Healthy Volunteers, Overweight, ObesityView official trial listing → -
Completed NCT NCT04251156
Research Study of How Well Semaglutide Works in People Living With Overweight or Obesity.
Not yet reported Novo Nordisk A/S 375 participants Est. completion 2022-08-23 33 sitesType 2 diabetes Other conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT04259801
First Research Study to Look at How Two Medicines, NNC0480-0389 and Semaglutide, Work Together in Healthy People, in People With High Body Weight and in People With Diabetes
Not yet reported Novo Nordisk A/S 152 participants Est. completion 2022-03-16 1 site Stand-aloneType 2 diabetes Other conditions: Healthy Volunteers, Overweight, ObesityView official trial listing → -
Completed NCT NCT04261933
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Germany, as Part of Local Clinical Practice (SURE GERMANY)
Novo Nordisk A/S 789 participants Est. completion 2021-05-25 95 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT04287179
SUSTAIN SWITCH: A Research Study to Compare Two Dose Schedules of Semaglutide Taken Once Weekly in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S Est. completion 2021-01-25 25 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04383197
Exercise and GLP-1 RA on Insulin Secretion
Not yet reported University of Copenhagen 30 participants Est. completion 2022-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04447859
16-week Flexible vs. 8-week Semaglutide Titration
Not yet reported Tel-Aviv Sourasky Medical Center 100 participants Est. completion 2022-09-10 1 siteOther conditions: Diabetes type2View official trial listing → -
Active, not recruiting NCT NCT04451837
Semaglutide and Dapagliflozin in Diabetic Patients With Different Pathophysiology
Not yet reported Region Skane 200 participants Est. completion 2026-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04466345
Semaglutide for the Treatment of Cognitive Dysfunction in Major Depressive Disorder
Not yet reported University Health Network, Toronto 72 participants Est. completion 2024-12-27 1 siteOther conditions: Major Depressive DisorderView official trial listing → -
Completed NCT NCT04469855
Post-Marketing Surveillance (Special Use-results Surveillance) on Long-term Use With Ozempic®
Novo Nordisk A/S 3217 participants Est. completion 2025-05-12 414 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04513704
A Clinical Trial Comparing Semaglutide in Healthy People Who Eat and Take the Medicine at Different Times
Not yet reported Novo Nordisk A/S 156 participants Est. completion 2021-05-26 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04515849
A Study of Cotadutide in Participants Who Have Chronic Kidney Disease With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 248 participants Est. completion 2022-03-08 83 sitesType 2 diabetesChronic kidney diseaseView official trial listing → -
Completed NCT NCT04524832
Research Study Comparing New Tablets of Semaglutide in New Doses, in Healthy People
Not yet reported Novo Nordisk A/S 290 participants Est. completion 2022-02-25 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04537624
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Switzerland, as Part of Local Clinical Practice
Novo Nordisk A/S 194 participants Est. completion 2023-05-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04537637
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Denmark, as Part of Local Clinical Practice
Novo Nordisk A/S 99 participants Est. completion 2023-05-08 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04538352
Transition From Basal/Bolus to Once-weekly Subcutaneous Semaglutide and Basal Insulin in Patients With T2D
Not yet reported The Cleveland Clinic 60 participants Est. completion 2023-11-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04559815
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Canada, as Part of Local Clinical Practice
Novo Nordisk A/S 194 participants Est. completion 2022-09-14 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04560998
A Research Study to Compare a Medicine Called Semaglutide Against Placebo in People With Peripheral Arterial Disease and Type 2 Diabetes
Not yet reported Novo Nordisk A/S 792 participants Est. completion 2024-07-12 283 sitesType 2 diabetes Other conditions: Peripheral Arterial DiseaseView official trial listing → -
Completed NCT NCT04572165
Epidemiological Assessment of the Risk for Pancreatic Cancer Associated With the Use of Semaglutide in Patients With Type 2 Diabetes - A Cohort Study Based on Nordic Registry Data
Novo Nordisk A/S 194928 participants Est. completion 2025-11-25 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04596631
A Research Study to Compare a New Medicine Oral Semaglutide to a Dummy Medicine in Children and Teenagers With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 132 participants Est. completion 2026-02-03 97 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04601740
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in The Netherlands, as Part of Local Clinical Practice
Novo Nordisk A/S 145 participants Est. completion 2022-12-19 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04601753
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Sweden, as Part of Local Clinical Practice
Novo Nordisk A/S 194 participants Est. completion 2023-03-03 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04615871
Semaglutide to Reduce Myocardial Injury in PATIents With COVID-19
Not yet reported Vladimír Džavík 400 participants Est. completion 2022-03-31 10 sites Stand-aloneOther conditions: Covid19, Myocardial InjuryView official trial listing → -
Terminated NCT NCT04624672
Treatment of GLP-1 for Diabetic Bariatric Patients
Not yet reported Geisinger Clinic 3 participants Est. completion 2022-08-17 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04639414
Combined Active Treatment in Type 2 Diabetes With NASH
Not yet reported German Diabetes Center 192 participants Est. completion 2025-11-17 26 sites Stand-aloneType 2 diabetesMASHMASLDView official trial listing → -
Completed NCT NCT04707469
Research Study to Compare Three Doses of Semaglutide Tablets Taken Once Daily in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1606 participants Est. completion 2023-03-08 228 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT04741074
Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy
Not yet reported Geisinger Clinic 15 participants Est. completion 2023-01-31 2 sitesChronic kidney diseaseType 2 diabetes Other conditions: Obesity, Severe ObesityView official trial listing → -
Completed NCT NCT04777396
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE)
Not yet reported Novo Nordisk A/S 1840 participants Est. completion 2026-01-30 447 sites Stand-aloneOther conditions: Early Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT04777409
A Research Study Investigating Semaglutide in People With Early Alzheimer's Disease (EVOKE Plus)
Not yet reported Novo Nordisk A/S 1840 participants Est. completion 2026-01-30 498 sites Stand-aloneOther conditions: Early Alzheimer´s DiseaseView official trial listing → -
Completed NCT NCT04779697
GLP-1 Analogue Effects on Food Cues, Stress, Motivation for Highly Palatable Foods, and Weight
Not yet reported Yale University 96 participants Est. completion 2024-11-19 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT04788511
Research Study to Investigate How Well Semaglutide Works in People Living With Heart Failure and Obesity
Not yet reported Novo Nordisk A/S 529 participants Est. completion 2023-04-18 146 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT04817644
A Research Study to See How Much Semaglutide and SNAC is in the Milk of Healthy, Breastfeeding Women Taking Semaglutide Tablets
Not yet reported Novo Nordisk A/S 14 participants Est. completion 2023-07-03 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04822181
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
Not yet reported Novo Nordisk A/S 1205 participants Est. completion 2029-04-25 558 sites Stand-aloneOther conditions: Non-alcoholic SteatohepatitisView official trial listing → -
Status unknown NCT NCT04854083
Semaglutide as an Adjunct to Dieting in the Treatment of Type 2 Diabetes
Not yet reported Kirsi Pietiläinen 50 participants Est. completion 2025-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04862923
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in the United Kingdom, as Part of Local Clinical Practice
Novo Nordisk A/S 336 participants Est. completion 2023-08-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04865744
The Effect of Semaglutide on Pituitary Function
Not yet reported University of Tartu 10 participants Est. completion 2021-09-30 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT04865770
A Research Study to Find Out How Semaglutide Works in the Kidneys Compared to Placebo, in People With Type 2 Diabetes and Chronic Kidney Disease (the REMODEL Trial)
Not yet reported Novo Nordisk A/S 106 participants Est. completion 2024-11-21 49 sites Stand-aloneType 2 diabetesChronic kidney diseaseView official trial listing → -
Completed NCT NCT04873245
Lifestyle Counseling and Medication for Adolescent Weight Management
Not yet reported University of Minnesota 120 participants Est. completion 2026-06-30 1 siteOther conditions: Obesity, ChildhoodView official trial listing → -
Completed NCT NCT04878393
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Japan, as Part of Local Clinical Practice
Novo Nordisk A/S 650 participants Est. completion 2023-02-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04878406
A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Japanese Men
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2021-07-20 1 site Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT04885634
Semaglutide for the Reduction of Arrhythmia Burden in Overweight AF Patients
Not yet reported Axel Brandes Est. completion 2024-11Other conditions: Atrial Fibrillation, Overweight and ObesityView official trial listing → -
Completed NCT NCT04889183
SeMaglutide and Albuminuria Reduction Trial in Obese Individuals Without Diabetes
Not yet reported University Medical Center Groningen 125 participants Est. completion 2024-05-28 13 sitesOther conditions: Obesity, AlbuminuriaView official trial listing → -
Active, not recruiting NCT NCT04892199
Does GLP-1RA Prevent Deterioration of Metabolic State in Prediabetic and Diabetic Patients Treated With Antipsychotic Medication?
Not yet reported Anders Fink-Jensen, MD, DMSci 104 participants Est. completion 2026-08-01 3 sitesType 2 diabetes Other conditions: Metabolic Disturbance, Schizophrenia, Clozapine, GLP-1, OlanzapineView official trial listing → -
Completed NCT NCT04916470
Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes
Not yet reported Novo Nordisk A/S 617 participants Est. completion 2023-10-11 180 sites Added to GLP-1Type 2 diabetesHeart failureView official trial listing → -
Terminated NCT NCT04938388
Comparison of Oral Semaglutide w/ Placebo- Treatment for Latino Adults w/T2 Diabetes Receiving Enhanced Lifestyle Care
Not yet reported Sansum Diabetes Research Institute 12 participants Est. completion 2023-02-16 1 siteType 2 diabetes Other conditions: Glucose Metabolism Disorders (Including Diabetes Mellitus)View official trial listing → -
Completed NCT NCT04940078
A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Combined Versus Separate Injections in People With Overweight or Obesity
Not yet reported Novo Nordisk A/S 40 participants Est. completion 2022-02-16 2 sites Stand-aloneOther conditions: Obesity & OverweightView official trial listing → -
Completed NCT NCT04944992
A Study of Efinopegdutide (MK-6024) in Participants With Nonalcoholic Fatty Liver Disease (NAFLD) (MK-6024-001)
Not yet reported Merck Sharp & Dohme LLC 145 participants Est. completion 2022-10-19 69 sitesMASLDMASHView official trial listing → -
Completed NCT NCT04969939
A Research Study to Investigate How Well NNC0165-1875 in Combination With Semaglutide Works in People With Obesity
Not yet reported Novo Nordisk A/S 120 participants Est. completion 2023-01-30 25 sites Added to GLP-1Other conditions: ObesityView official trial listing → -
Completed NCT NCT04972721
SELECT-LIFE: A Research Study Looking at Long-term Effects of Semaglutide in People Who Took Part in the SELECT Cardiovascular Outcomes Trial
Novo Nordisk A/S 3439 participants Est. completion 2025-08-25 38 sitesOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT04979130
Comparing Semaglutide Versus Placebo on Intestinal Barrier Function in Type 2 Diabetes Mellitus (SIB)
Not yet reported University of Colorado, Denver 69 participants Est. completion 2024-10-16 1 site Stand-aloneType 2 diabetes Other conditions: Chronic Inflammation, Intestinal PermeabilityView official trial listing → -
Completed NCT NCT04982575
Research Study to Look at How Well Cagrilintide Together With Semaglutide Works in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 92 participants Est. completion 2022-07-07 23 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04990024
The Effect of Different Diets on Arterial Stiffness in Obese Patients on Semaglutide
Not yet reported American University of Beirut Medical Center 60 participants Est. completion 2025-09-15 1 siteOther conditions: Obesity, Weight LossView official trial listing → -
Completed NCT NCT04998136
Research Study Investigating How Well Semaglutide Works in People From Thailand and South Korea Living With Obesity
Not yet reported Novo Nordisk A/S 150 participants Est. completion 2023-11-20 16 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT05013229
A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Insulin Glargine Taken Daily With Insulin Aspart (COMBINE 3)
Not yet reported Novo Nordisk A/S 679 participants Est. completion 2023-11-14 182 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05016882
Research Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non-alcoholic Steatohepatitis (NASH)
Not yet reported Novo Nordisk A/S 698 participants Est. completion 2025-03-14 255 sites Stand-aloneOther conditions: Non-alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT05035082
A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE)
Not yet reported Novo Nordisk A/S 1018 participants Est. completion 2025-06-18 25 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05035095
Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in People Who Are Overweight or Living With Obesity (OASIS 1)
Not yet reported Novo Nordisk A/S 667 participants Est. completion 2023-05-12 56 sites Stand-aloneOther conditions: Obesity, OverweightView official trial listing → -
Active, not recruiting NCT NCT05040087
Changing the Natural History of Type 2 Diabetes ("CHANGE" Study)
Not yet reported Foundation for Atlanta Veterans Education and Research, Inc. 127 participants Est. completion 2028-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05040971
Research Study Looking at How Well Semaglutide Works in People Living With Obesity and Prediabetes
Not yet reported Novo Nordisk A/S 207 participants Est. completion 2023-07-14 43 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT05046873
A Research Study Looking Into Blood Levels of Semaglutide and NNC0480-0389 When Given in the Same Injection or in Two Separate Injections in Healthy People
Not yet reported Novo Nordisk A/S 16 participants Est. completion 2022-01-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05064735
Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee Osteoarthritis
Not yet reported Novo Nordisk A/S 407 participants Est. completion 2023-09-08 122 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT05067621
Semaglutide Effects in Obese Youth With Prediabetes/New Onset Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease
Not yet reported Yale University 60 participants Est. completion 2027-01 1 siteType 2 diabetesPrediabetes Other conditions: Non-Alcoholic Fatty Liver Disease, Obesity, ChildhoodView official trial listing → -
Status unknown NCT NCT05071417
Effect Of Semaglutide In Coronary Atheroma Plaque
Not yet reported Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León 120 participants Est. completion 2025-12 Stand-aloneOther conditions: Atheroscleroses, CoronaryView official trial listing → -
Active, not recruiting NCT NCT05073835
Semaglutide 2.4 mg in Patients With Poor Weight-loss
Not yet reported University College, London 70 participants Est. completion 2025-09 1 site Stand-aloneMetabolic syndrome Other conditions: Obesity, DiabetesView official trial listing → -
Completed NCT NCT05078255
The Separate and Combined Effects of Long-term GIP and GLP-1 Receptor Activation in Patients with Type 2 Diabetes
Not yet reported Asger Lund, MD 61 participants Est. completion 2025-01-24 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT05087342
Latino Semaglutide Study
Not yet reported Loma Linda University 119 participants Est. completion 2024-05-29 1 siteOther conditions: Obesity, Obesity; Drug, Overweight or Obesity, Weight Loss, Weight Loss Trajectory, Weight, BodyView official trial listing → -
Completed NCT NCT05129891
A Research Study Looking at New Protein-based Tablets in Healthy Male Participants
Not yet reported Novo Nordisk A/S 384 participants Est. completion 2023-05-04 2 sites Added to GLP-1Type 2 diabetes Other conditions: Healthy Volunteers, High Blood Cholesterol LevelsView official trial listing → -
Completed NCT NCT05132088
Research Study to Investigate How Well Semaglutide Tablets Taken Once Daily Work in East Asian People Who Are Overweight or Living With Obesity
Not yet reported Novo Nordisk A/S 201 participants Est. completion 2023-09-01 15 sites Stand-aloneOther conditions: Overweight and ObesityView official trial listing → -
Completed NCT NCT05136287
SEMAGLUTIDE VERSUS GLP-1 RECEPTOR AGONISTS. EFFECTIVENESS , SAFETY AND QUALITY OF LIFE IN PATIENTS WITH DIABETES MELLITUS 2. OBSERVATIONAL, PROSPECTIVE AND MULTICENTER STUDY. SEVERAL STUDY.
Jose Seijas Amigo 140 participants Est. completion 2024-01-01 11 sitesType 2 diabetes Other conditions: Weight Loss, Quality of Life, Safety IssuesView official trial listing → -
Completed NCT NCT05144984
A Research Study Looking at How Well a Combination of the Medicines Semaglutide and NNC0480-0389 Works in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 500 participants Est. completion 2023-03-23 129 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05147896
Semaglutide Anti-Atherosclerotic Mechanisms of Action Study in Type 2 Diabetes Patients
Not yet reported University Medical Centre Ljubljana 100 participants Est. completion 2023-12-01 1 siteType 2 diabetes Other conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT05153564
A Research Study Looking Into the Effect of Semaglutide and NNC0480 0389 on Blood Levels of a Birth Control Pill in Woman After Menopause
Not yet reported Novo Nordisk A/S 27 participants Est. completion 2022-09-01 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05161429
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
Brigham and Women's Hospital 550000 participants Est. completion 2024-06-30 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05193578
Home-based Intervention With Semaglutide Treatment Of Neuroleptica-Related Prediabetes
Not yet reported Jan Frystyk 154 participants Est. completion 2024-05-01 1 siteOther conditions: Schizophrenia, Prediabetic StateView official trial listing → -
Enrolling by invitation NCT NCT05195944
Semaglutide vs Sitagliptin
Not yet reported University Health Network, Toronto 58 participants Est. completion 2026-12 1 siteMASHMASLD Other conditions: Liver Transplant; Complications, Diabetes MellitusView official trial listing → -
Active, not recruiting NCT NCT05202353
A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver
Not yet reported Boehringer Ingelheim 29 participants Est. completion 2027-02-03 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT05205928
Weekly Subcutaneous Semaglutide as Adjunct to Closed-loop Therapy in Type 1 Diabetes Care
Not yet reported, Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 28 participants Est. completion 2024-06-30 1 siteOther conditions: Type 1 Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Suspended NCT NCT05209165
Semaglutide to Reduce Atrial Fibrillation Burden
Not yet reported San Francisco Veterans Affairs Medical Center 132 participants Est. completion 2028-05 1 site Stand-aloneOther conditions: Atrial Fibrillation, Obesity, OverweightView official trial listing → -
Active, not recruiting NCT NCT05220917
Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study
Brigham and Women's Hospital 781430 participants Est. completion 2027-09-30 1 siteType 2 diabetes Other conditions: Cardiovascular Events, Renal DiseaseView official trial listing → -
Completed NCT NCT05227196
A Research Study Looking at the Comparability of 2 Different Forms of Oral Semaglutide in Healthy People
Not yet reported Novo Nordisk A/S 546 participants Est. completion 2023-08-08 3 sitesType 2 diabetes Other conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT05230589
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Saudi Arabia, as Part of Local Clinical Practice
Novo Nordisk A/S 194 participants Est. completion 2023-03-13 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05230615
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Italy, as Part of Local Clinical Practice
Novo Nordisk A/S 458 participants Est. completion 2023-10-31 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05232708
A Clinical Trial Looking at the Comparability of 2 Different Forms of Semaglutide
Not yet reported Novo Nordisk A/S 18 participants Est. completion 2022-08-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05236517
A Research Study Looking at How 50 mg Semaglutide Daily Affects Food Intake and Emptying of the Stomach in People With Obesity
Not yet reported Novo Nordisk A/S 60 participants Est. completion 2022-11-07 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT05249881
"Efficacy of Once Weekly GLP 1 Analogue: Semaglutide. A Multicenter Experience From Pakistan."
Not yet reported Aga Khan University 300 participants Est. completion 2022-12 2 sitesType 2 diabetes Other conditions: Weight Change, BodyView official trial listing → -
Active, not recruiting NCT NCT05254314
Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3)
Not yet reported Vanderbilt University Medical Center 100 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: AsthmaView official trial listing → -
Completed NCT NCT05259033
A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Semaglutide (COMBINE 2)
Not yet reported Novo Nordisk A/S 683 participants Est. completion 2024-01-16 193 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05302596
Semaglutide Use in Elderly Obese Patients
Not yet reported State University of New York at Buffalo 16 participants Est. completion 2024-10-30 1 site Stand-aloneOther conditions: Obesity, AgingView official trial listing → -
Completed NCT NCT05303857
Analyse the Effect of Semaglutide on Vascular Structure and Function in Patients With Early Type 2 Diabetes
Not yet reported University of Erlangen-Nürnberg Medical School 107 participants Est. completion 2025-04-17 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05316662
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Mexico, as Part of Local Clinical Practice
Novo Nordisk A/S 187 participants Est. completion 2024-04-06 2 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT05322200
The POST-ACS Study
Not yet reported Swansea Bay University Health Board 140 participants Est. completion 2024-08-01 1 siteCardiovascular disease Other conditions: Diabetes Mellitus, Acute Coronary SyndromeView official trial listing → -
Active, not recruiting NCT NCT05333003
Semaglutide in Comorbid Schizophrenia Spectrum Disorder and Obesity
Not yet reported Centre for Addiction and Mental Health 92 participants Est. completion 2026-08 1 site Stand-aloneOther conditions: Schizophrenia Spectrum DisordersView official trial listing → -
Completed NCT NCT05371496
Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction
Not yet reported Mayo Clinic 81 participants Est. completion 2026-07-17 1 siteHeart failure Other conditions: Cardiomyopathy, ObesityView official trial listing → -
Completed NCT NCT05390307
Obesity Treatment to Improve Diabetes
Not yet reported Dasman Diabetes Institute 60 participants Est. completion 2024-01-01 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05394519
A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose Weight
Not yet reported Novo Nordisk A/S 1200 participants Est. completion 2025-02-03 179 sites Stand-aloneType 2 diabetes Other conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT05429593
A Research Study Investigating How Semaglutide and Dapagliflozin Act in Your Body When Dosed in One Tablet
Not yet reported Novo Nordisk A/S 152 participants Est. completion 2023-04-13 2 sites Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT05435677
A Research Study to Look at How Insulin Icodec and Semaglutide Work in the Body of People From China With Type 2 Diabetes When Given Alone or Together
Not yet reported Novo Nordisk A/S 20 participants Est. completion 2023-04-25 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05441267
A Study of Cardiovascular Events iN Diabetes Plus
Not yet reported University of Oxford 21296 participants Est. completion 2048-08-17 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05442450
Efficacy of Oral Semaglutide in Overweight or Obesity
Not yet reported Asian Institute of Gastroenterology, India 116 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: Obesity, Weight LossView official trial listing → -
Completed NCT NCT05443191
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Finland, as Part of Local Clinical Practice
Novo Nordisk A/S 50 participants Est. completion 2023-04-27 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05443334
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Spain, as Part of Local Clinical Practice
Novo Nordisk A/S 465 participants Est. completion 2024-07-04 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05443568
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Israel, as Part of Local Clinical Practice
Novo Nordisk A/S 155 participants Est. completion 2024-11-16 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT05444153
Research Study to Compare Semaglutide Tablets With Empagliflozin Tablets Taken Once Daily in People With Type 2 Diabetes and Obesity
Not yet reported Novo Nordisk A/S Est. completion 2025-08-29 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05468632
A Study in North Macedonia Investigating Retrospective Data of Glucagon-like Peptide-1 (GLP-1) Participants With Type 2 Diabetes (T2D) in Real World Environment (RWE) Setting (MIRAGE)
Novo Nordisk A/S 314 participants Est. completion 2022-07-31 17 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT05473286
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Germany, as Part of Local Clinical Practice
Novo Nordisk A/S Est. completion 2024-05-16Type 2 diabetesView official trial listing → -
Completed NCT NCT05478252
A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 388 participants Est. completion 2023-09-18 104 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05486065
A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and Overweight
Not yet reported Novo Nordisk A/S 245 participants Est. completion 2023-12-13 130 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05492305
Glucagon-like Peptide 1 (GLP1) Receptor Agonists and Mental Health
King's College London 20 participants Est. completion 2023-08 1 siteOther conditions: Diabetes Mellitus, Obesity, Mental Health IssueView official trial listing → -
Completed NCT NCT05498610
A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Chinese Men
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2022-10-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05502562
A Research Study to Understand How Oral Semaglutide Works in People With Type 2 Diabetes in India
Novo Nordisk A/S 388 participants Est. completion 2024-06-03Type 2 diabetesView official trial listing → -
Enrolling by invitation NCT NCT05503927
A Study to Evaluate the Safety of Exposure to Wegovy During Pregnancy
Novo Nordisk A/S 2701 participants Est. completion 2027-08-15 2 sitesOther conditions: Pregnancy, Obesity, OverweightView official trial listing → -
Completed NCT NCT05514535
A Research Study to Look Into How Semaglutide, Together With a Lower Dose of Insulin Glargine, Compares to a Higher Dose of Insulin Glargine Alone in People With Type 2 Diabetes (SUSTAIN OPTIMIZE)
Not yet reported Novo Nordisk A/S 573 participants Est. completion 2025-04-09 239 sites Stand-aloneType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT05520775
Semaglutide for Alcohol Use Disorder
Not yet reported University of North Carolina, Chapel Hill 48 participants Est. completion 2024-04-19 1 site Stand-aloneAlcohol use disorder Other conditions: Cigarette SmokingView official trial listing → -
Completed NCT NCT05530577
Effects of Semaglutide on Nicotine Intake
Not yet reported University of North Carolina, Chapel Hill 24 participants Est. completion 2024-05-13 1 site Stand-aloneOther conditions: Tobacco Use Disorder, Nicotine AddictionView official trial listing → -
Completed NCT NCT05537233
ADJUnct Semaglutide Treatment in Type 1 Diabetes
Not yet reported Viral N. Shah 115 participants Est. completion 2024-08-06 4 sites Stand-aloneOther conditions: Type 1 Diabetes, ObesityView official trial listing → -
Completed NCT NCT05548647
Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects
Not yet reported University of Pennsylvania 120 participants Est. completion 2025-05-12 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT05564117
Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in People Who Have a Body Weight Above the Healthy Range
Not yet reported Novo Nordisk A/S 307 participants Est. completion 2024-05-07 23 sites Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Active, not recruiting NCT NCT05567796
A Research Study to See How Well CagriSema Helps People With Excess Body Weight Lose Weight
Not yet reported Novo Nordisk A/S 3400 participants Est. completion 2026-10-19 256 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT05574439
Young Adults With Early-onset Obesity Treated With Semaglutide
Not yet reported Signe Torekov 246 participants Est. completion 2026-04-01 2 sitesOther conditions: Obesity, AdolescentView official trial listing → -
Completed NCT NCT05579249
A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in America
Not yet reported Novo Nordisk A/S 500 participants Est. completion 2024-11-27 1 siteOther conditions: ObesityView official trial listing → -
Terminated NCT NCT05579977
Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People With Obesity
Not yet reported Pfizer 902 participants Est. completion 2023-09-22 90 sitesOther conditions: Diabetes Mellitus, ObesityView official trial listing → -
Status unknown NCT NCT05597202
Does the Hematopoietic Stem Cell Govern Residual Inflammatory Cardiovascular Risk in Type 2 Diabetes
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 22 participants Est. completion 2024-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05616013
Safety and Efficacy of Bimagrumab and Semaglutide in Adults Who Are Overweight or Obese
Not yet reported Eli Lilly and Company 507 participants Est. completion 2025-06-14 26 sites Stand-aloneOther conditions: Obesity, Obese, Overweight or ObesityView official trial listing → -
Status unknown NCT NCT05616052
Comparison of Body Weight Change Through Different Smeglutide Administration Methods
Not yet reported Huashan Hospital 80 participants Est. completion 2023-12-01 1 siteOther conditions: Weight Change, BodyView official trial listing → -
Active, not recruiting NCT NCT05622045
Does Personality Predict Patient Adherence, Health Behaviors, and Weight Loss Outcomes During the Latino Crossover Semaglutide Study (LCSS)? (Story-LCSS Project)
Loma Linda University 59 participants Est. completion 2027-05 1 siteOther conditions: Obesity, Body Weight ChangesView official trial listing → -
Status unknown NCT NCT05646199
Semaglutide vs Metformin in Polycystic Ovary Syndrome (PCOS)
Not yet reported, Not yet reported University of Hull 60 participants Est. completion 2025-12-30 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT05646706
A Research Study to See How Semaglutide Helps People With Excess Weight, Lose Weight (STEP UP)
Not yet reported Novo Nordisk A/S 1407 participants Est. completion 2024-11-26 107 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT05649137
A Research Study to See How Semaglutide Helps People With Excess Weight and Type 2 Diabetes Lose Weight
Not yet reported Novo Nordisk A/S 512 participants Est. completion 2024-12-13 76 sites Stand-aloneType 2 diabetes Other conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT05669755
REDEFINE 3: A Research Study to See the Effects of CagriSema in People Living With Diseases in the Heart and Blood Vessels
Not yet reported Novo Nordisk A/S 7101 participants Est. completion 2027-10-14 633 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT05670379
Assessment of Safety, Tolerability and Drug Levels of Exenatide Implant
Not yet reported Vivani Medical, Inc 24 participants Est. completion 2025-08-21 1 siteOther conditions: Overweight and Obesity, Type2diabetesView official trial listing → -
Terminated NCT NCT05671653
A Study to Evaluate the Effect of the Experimental GLP-1 Drug PF-07081532 on Blood Levels of Common Birth Control Pills, and Drugs Omeprazole and Midazolam, and Effect of GLP-1 Drug Semaglutide on Midazolam Blood Levels in Healthy Adults With Weight in the Obesity Range
Not yet reported Pfizer 32 participants Est. completion 2023-11-03 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT05689099
A Research Trial Looking at the Comparability of 2 Different Concentrations of Semaglutide for the 0.5 Milligram (mg) Dose
Not yet reported Novo Nordisk A/S 20 participants Est. completion 2023-05-30 1 site Stand-aloneType 2 diabetes Other conditions: Healthy ParticipantsView official trial listing → -
Enrolling by invitation NCT NCT05689372
Regulatory Post Marketing Surveillance (rPMS) Study of Ozempic (Semaglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea
Novo Nordisk A/S 600 participants Est. completion 2027-05-31 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05702905
Semaglutide Improves Metabolic Abnormalities and Fertility in Obese Infertile Women With Polycystic Ovary Syndrome
Not yet reported Peking University First Hospital 75 participants Est. completion 2025-06-30 1 siteOther conditions: PCOS (Polycystic Ovary Syndrome), SemaglutideView official trial listing → -
Not yet recruiting NCT NCT05714683
Regulatory Post Marketing Surveillance (rPMS) Study of Rybelsus (Oral Semaglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea
Novo Nordisk A/S 600 participants Est. completion 2026-10-30Type 2 diabetesView official trial listing → -
Completed NCT NCT05716724
O-SEMA-Fast: A Research Study to Understand How Oral Semaglutide Works in People With Type 2 Diabetes Who Plan to Fast During Ramadan in the United Arab Emirates, Saudi Arabia, and Kuwait
Novo Nordisk A/S 288 participants Est. completion 2023-07-09 20 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05726227
A Research Study on How Well Semaglutide Helps Children and Teenagers With Excess Body Weight Lose Weight
Not yet reported Novo Nordisk A/S 210 participants Est. completion 2026-12-07 56 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT05751226
A Study in People With Overweight or Obesity to Test How Well Different Doses of BI 1820237 Are Tolerated When Given Alone or in Combination With Either Semaglutide or BI 456906
Not yet reported Boehringer Ingelheim 88 participants Est. completion 2024-08-01 1 site Stand-aloneOther conditions: Healthy, ObesityView official trial listing → -
Status unknown NCT NCT05751720
Effect on Non-Alcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus With Gastric Inhibitory Polypeptide/Glucagon Like Peptide-1 Analogue
Not yet reported, Not yet reported Dr Adnan Agha 30 participants Est. completion 2025-02 1 siteType 2 diabetes Other conditions: Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis, Liver FatView official trial listing → -
Completed NCT NCT05755360
DOORS: A Research Study to Understand How Oral Semaglutide Works in People With Type 2 Diabetes Who Change From Dipeptidyl Peptidase-4 Inhibitor (DPP4i) Treatment to Oral Semaglutide in Italy
Novo Nordisk A/S 291 participants Est. completion 2024-10-21 25 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05756764
Anti-obesity Pharmacotherapy and Inflammation
Louisiana State University Health Sciences Center in New Orleans 30 participants Est. completion 2026-02-20 2 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT05766709
A Research Study Comparing Blood Levels of Medicines NNC0194-0499 and Semaglutide Administered as a Combination Formulation Versus Two Separate Formulations
Not yet reported Novo Nordisk A/S 53 participants Est. completion 2024-02-09 1 site Stand-aloneOther conditions: Non-alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT05768945
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM)- Semaglutide v DPP4 Inhibitors
Brigham and Women's Hospital 742670 participants Est. completion 2023-12-31 1 siteOther conditions: DiabetesView official trial listing → -
Status unknown NCT NCT05779644
Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes Mellitus
Not yet reported RenJi Hospital 300 participants Est. completion 2025-02-23 1 site Stand-aloneType 2 diabetes Other conditions: Metformin, Obesity, Abdominal, Abdominal Fat, Non-Alcoholic Fatty Liver Disease, Metabolism Disorder, Glucose, Metabolism Disorder, LipidView official trial listing → -
Completed NCT NCT05784402
A Research Study to Compare How Much Semaglutide is Found in the Blood With Different Tablets of Oral Semaglutide in Healthy Participants
Not yet reported Novo Nordisk A/S 264 participants Est. completion 2024-03-29 3 sites Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT05786521
Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older Adults
Not yet reported The University of Texas Health Science Center at San Antonio 20 participants Est. completion 2024-05-20 1 site Stand-aloneType 2 diabetesPrediabetes Other conditions: Aging, Overweight and ObesityView official trial listing → -
Completed NCT NCT05788965
Semaglutide in CFRD
Not yet reported, Not yet reported University of Minnesota 8 participants Est. completion 2024-12-31 1 siteOther conditions: Cystic Fibrosis, Cystic Fibrosis-related DiabetesView official trial listing → -
Withdrawn NCT NCT05812183
Gastric Sleeve-Induced Weight Loss on Shortness of Breath in Obesity
Not yet reported University of California, Los Angeles Est. completion 2025-02-12 Stand-aloneOther conditions: Dyspnea, Quality of LifeView official trial listing → -
Completed NCT NCT05813249
Semaglutide in Nonalcoholic Fatty Liver Disease
Not yet reported Zagazig University 180 participants Est. completion 2024-04-01 1 siteOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT05813912
A Research Study to See How a New Weekly Insulin, Insulin Icodec When Given Along With Semaglutide Helps in Reducing the Blood Sugar Level in Patients With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 148 participants Est. completion 2025-05-16 39 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05813925
A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose Weight
Not yet reported Novo Nordisk A/S 331 participants Est. completion 2025-03-07 28 sites Stand-aloneOther conditions: Obesity or OverweightView official trial listing → -
Completed NCT NCT05816057
A Study of the Efficacy and Safety of Semaglutide Injection in the Treatment of Type 2 Diabetes Mellitus
Not yet reported Hangzhou Jiuyuan Gene Engineering Co. Ltd., 476 participants Est. completion 2023-10-31 35 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05822830
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities
Not yet reported Eli Lilly and Company 751 participants Est. completion 2024-11-13 32 sitesOther conditions: Obesity, OverweightView official trial listing → -
Withdrawn NCT NCT05829460
Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia
Not yet reported Washington University School of Medicine Est. completion 2032-04-30 Stand-aloneOther conditions: Endometrial HyperplasiaView official trial listing → -
Completed NCT NCT05857085
Novel Therapeutics and Endothelial Dysfunction in T1DM Patients
Not yet reported General and Teaching Hospital Celje 90 participants Est. completion 2023-04-20 1 siteOther conditions: Endothelial Dysfunction, Diabetes Mellitus, Type 1, Biomarkers, Endothelial Progenitor Cells, SGLT 2 Inhibitors, Incretins, Glucose Excursions, FMD, FPF, Arterial StiffnessView official trial listing → -
Enrolling by invitation NCT NCT05872022
A Study to Evaluate Safety of Exposure to Wegovy During Pregnancy
Novo Nordisk A/S 728 participants Est. completion 2032-12-30 3 sitesOther conditions: Pregnancy, Obesity, OverweightView official trial listing → -
Completed NCT NCT05877547
A Clinical Study of Efinopegdutide in Participants With Precirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-6024-013)
Not yet reported Merck Sharp & Dohme LLC 381 participants Est. completion 2025-12-29 175 sitesMASLDMASH Other conditions: Non-alcoholic Fatty Liver Disease, Fatty Liver, NonalcoholicView official trial listing → -
Completed NCT NCT05890976
Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in Chinese Adults Who Are Above a Healthy Weight Range (OASIS 3)
Not yet reported Novo Nordisk A/S 200 participants Est. completion 2025-01-16 16 sitesOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT05891496
A Research Study Looking at the Effect of Semaglutide on the Immune System and Other Biological Processes in People With Alzheimer's Disease
Not yet reported Novo Nordisk A/S 23 participants Est. completion 2025-09-08 12 sites Stand-aloneOther conditions: Alzheimers DiseaseView official trial listing → -
Completed NCT NCT05891587
Semaglutide Therapy for Alcohol Reduction - Tulsa
Not yet reported Oklahoma State University Center for Health Sciences 80 participants Est. completion 2025-10-01 1 site Stand-aloneAlcohol use disorderView official trial listing → -
Completed NCT NCT05895643
Does Semaglutide Reduce Alcohol Intake in Patients With Alcohol Use Disorder and Comorbid Obesity?
Not yet reported Psychiatric Centre Rigshospitalet 108 participants Est. completion 2025-07-31 1 site Stand-aloneAlcohol use disorder Other conditions: Alcohol Abuse, Alcohol AddictionView official trial listing → -
Terminated NCT NCT05897372
Feasibility of Aggressive Albuminuria Reduction in Biopsy-Proven Diabetic Nephropathy - a Pilot Study
Not yet reported Iain Bressendorff 1 participants Est. completion 2024-09-23 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT05897398
SEMASEARCH, Retrospective/Prospective Cohort Nested at ATUc/AP2 WEGOVY®
Hospices Civils de Lyon 1100 participants Est. completion 2025-06-10 14 sitesOther conditions: Obesity, Bariatric Surgery, Binge Eating Disorder, Syndromic Obesity, Sarcopenic Obesity, Iatrogenic Obesity, Psychotropic DrugsView official trial listing → -
Completed NCT NCT05920889
Glucagon-like Peptide 1 Receptor Agonist in Acute Large Vessel Occlusion Stroke Treated by Reperfusion Therapies
Not yet reported Chinese University of Hong Kong 140 participants Est. completion 2024-10-25 2 sitesCardiovascular disease Other conditions: Brain DiseasesView official trial listing → -
Status unknown NCT NCT05950516
Efficacy and Safety of Semaglutide Ingection in Subjects With Type 2 Diabetes
Not yet reported Qilu Pharmaceutical Co., Ltd. 478 participants Est. completion 2025-01-22 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05984238
A Trial to Evaluate Safety, Feasibility and Efficacy of Endoscopic Duodenal PEF Therapy
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 33 participants Est. completion 2026-05-28 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05996848
A Research Study to See How Well CagriSema Helps People in China With Excess Body Weight Lose Weight
Not yet reported Novo Nordisk A/S 300 participants Est. completion 2025-02-22 37 sites Stand-aloneOther conditions: Obesity or OverweightView official trial listing → -
Completed NCT NCT05996874
A Research Study Comparing the Effect of Different Dosing Conditions on Blood Levels of Semaglutide in a New Tablet Composition in Healthy Participants
Not yet reported Novo Nordisk A/S 121 participants Est. completion 2024-04-18 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Active, not recruiting NCT NCT06005012
Semaglutide Treatment in the Real-world for Fibrosis Due to NAFLD in Obesity and T2DM
Not yet reported University of California, San Diego 120 participants Est. completion 2026-12-31 1 site Stand-aloneType 2 diabetes Other conditions: Fibrosis, Liver, Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT06027567
The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial Pressure
Not yet reported Rigmor Højland Jensen 38 participants Est. completion 2025-10-28 2 sites Stand-aloneOther conditions: Idiopathic Intracranial Hypertension, Intracranial Pressure, Obesity, Pseudotumor Cerebri Syndrome, Papilledema, Weight LossView official trial listing → -
Completed NCT NCT06041217
A Research Study to See How Well Semaglutide Helps People Who Have a Body Weight Above the Healthy Weight Range
Not yet reported Novo Nordisk A/S 242 participants Est. completion 2025-05-07 21 sites Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Active, not recruiting NCT NCT06042153
DIALYSIS-TIR Study
Not yet reported University of Texas Southwestern Medical Center 43 participants Est. completion 2028-09 5 sites Stand-aloneType 2 diabetes Other conditions: End Stage Renal Disease on DialysisView official trial listing → -
Completed NCT NCT06045221
A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin
Not yet reported Eli Lilly and Company 1698 participants Est. completion 2025-08-22 131 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06050577
The Effect of Oral Semaglutide on Bone Turnover in Patients With T2D: a Randomized Placebo-controlled Clinical Trial
Not yet reported Odense University Hospital 64 participants Est. completion 2027-01-15 1 site Stand-aloneType 2 diabetes Other conditions: OsteopeniaView official trial listing → -
Status unknown NCT NCT06057077
Semaglutide GLP1 Agonists With Degludec Basal-bolus Insulin in Early Type 1 Diabetes to Basal-bolus
Not yet reported, Not yet reported Ministry of Health, Saudi Arabia 120 participants Est. completion 2024-12-31Other conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT06065540
A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Not yet reported Novo Nordisk A/S 2734 participants Est. completion 2026-01-06 405 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT06083675
Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S Est. completion 2027-05-28 100 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06097390
A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation III
Not yet reported Novo Nordisk A/S 121 participants Est. completion 2024-03-27 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT06118008
A Study of HS-20094 in T2DM Participants
Not yet reported Jiangsu Hansoh Pharmaceutical Co., Ltd. 54 participants Est. completion 2024-01-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06118203
Semaglutide Use in Acute Pulmonary Embolism
Imperial College London 18 participants Est. completion 2023-03-05 1 siteOther conditions: Pulmonary EmbolismView official trial listing → -
Completed NCT NCT06120556
Efficacy of Glucagon-like Peptide-1 Receptor Agonists According to Type 2 Diabetes Subtypes
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari 130 participants Est. completion 2023-10-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06131372
A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo
Not yet reported Novo Nordisk A/S 626 participants Est. completion 2025-11-06 128 sitesChronic kidney diseaseType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT06131437
A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight
Not yet reported Novo Nordisk A/S 809 participants Est. completion 2026-01-09 46 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT06154486
Evaluation of Gastric Content of Volunteers Fasting and Using Semaglutide: an Observational and Cross-sectional Study
Hospital Israelita Albert Einstein 30 participants Est. completion 2023-08-22 1 siteOther conditions: Pneumonia, Aspiration, AnesthesiaView official trial listing → -
Completed NCT NCT06161844
Efficacy and Safety of Semaglutide Injection (HD1916) in Patients With Type 2 Diabetes Mellitus
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 506 participants Est. completion 2025-05-14 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT06182618
Retrospective Analysis for Patients With Metabolic Syndrome
Second Affiliated Hospital, Zhejiang University, School of Medicine 400 participants Est. completion 2024-01-01 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT06215196
Effectiveness and Safety of Semaglutide Combined With Dietary Fiber (Soloways) in Adults With Overweight or Obesity
Not yet reported S.LAB (SOLOWAYS) 81 participants Est. completion 2023-08-20 1 site Stand-aloneOther conditions: Overweight and ObesityView official trial listing → -
Completed NCT NCT06221696
Preventing Weight Regain Post-Semaglutide Treatment With Active Fiber Supplement (Soloways)
Not yet reported S.LAB (SOLOWAYS) 160 participants Est. completion 2023-12-01 1 siteOther conditions: Overweight and ObesityView official trial listing → -
Completed NCT NCT06221969
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Not yet reported Novo Nordisk A/S 1024 participants Est. completion 2026-04-06 197 sites Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT06222437
Semaglutide and Polycystic Ovarian Syndrome: an Emerging Treatment Strategy
Not yet reported Methodist Health System Est. completion 2027-02 Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Active, not recruiting NCT NCT06234111
Semaglutide and Physical Activity for Obesity and Multimorbidity
Hvidovre University Hospital 35 participants Est. completion 2026-11 1 siteOther conditions: Obesity Morbid, Multimorbidity, ObesityView official trial listing → -
Status unknown NCT NCT06243536
The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients
Not yet reported University Hospital Sestre Milosrdnice 60 participants Est. completion 2024-12-31 1 siteType 2 diabetes Other conditions: Overweight, Disordered Eating BehaviorsView official trial listing → -
Status unknown NCT NCT06256549
A Study of GZR18 Injection in Chinese Patients With Type 2 Diabetes Mellitus
Not yet reported Gan and Lee Pharmaceuticals, USA 272 participants Est. completion 2024-07-20 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06260722
Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)
Not yet reported Eli Lilly and Company 1250 participants Est. completion 2027-01 77 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06263595
Semaglutide and Preoperative Residual Gastric Volumes
University of Calgary 94 participants Est. completion 2025-05-16 1 siteOther conditions: Pulmonary AspirationView official trial listing → -
Completed NCT NCT06267092
A Study of How CagriSema Works on Appetite in People With Excess Body Weight
Not yet reported Novo Nordisk A/S 164 participants Est. completion 2025-12-08 1 site Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT06269107
A Research Study to See How Well New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Levels in People With Type 2 Diabetes (T2D), Compared to Daily Insulin Glargine (COMBINE 4)
Not yet reported Novo Nordisk A/S 485 participants Est. completion 2025-07-08 118 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06269120
SEMA-CardioDiab HUNGARY: A Research Study to Understand the Effects of Oral Semaglutide on Blood Sugar Levels, Weight, and Cardiovascular Risk in People With Type 2 Diabetes Patients in Hungary
Novo Nordisk A/S 243 participants Est. completion 2026-05-05 19 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06282458
Dose-Finding Study Evaluating Effect on Body Composition of Enobosarm in Patients Taking a GLP-1 for Chronic Weight Mgmt
Not yet reported Veru Inc. 168 participants Est. completion 2025-08-22 14 sitesOther conditions: Muscle Loss, ObesityView official trial listing → -
Active, not recruiting NCT NCT06283667
Special Use - Results Surveillance on Long-term Use With Wegovy®
Novo Nordisk A/S 1071 participants Est. completion 2028-01-31 112 sitesOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT06287307
Semaglutide 2.4mg for Low Responders After Bariatric Surgery
Not yet reported Zuyderland Medisch Centrum 152 participants Est. completion 2026-09Other conditions: Obesity, Obesity, Morbid, Weight GainView official trial listing → -
Completed NCT NCT06289504
A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body Weight
Not yet reported Novo Nordisk A/S 34 participants Est. completion 2024-11-15 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT06292065
Gastric Ultrasound To Assess Gastric Contents In Patients On Semaglutide Therapy
Not yet reported Nils Vlaeminck 88 participants Est. completion 2025-05-31 1 siteOther conditions: GastroparesisView official trial listing → -
Active, not recruiting NCT NCT06299098
A Study to Test if Trevogrumab or Trevogrumab With Garetosmab When Taken With Semaglutide is Safe and How Well They Work in Adult Patients With Obesity for Weight Loss, Fat Loss, and Lean Mass Preservation
Not yet reported Regeneron Pharmaceuticals 1005 participants Est. completion 2026-10-21 60 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT06301191
The Effect of Semaglutide on Cardiovascular Markers and Liver Function
Attikon Hospital 50 participants Est. completion 2024-05-01 1 siteOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT06323161
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without Metformin
Not yet reported Novo Nordisk A/S 274 participants Est. completion 2025-10-23 61 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06323174
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and Exercise
Not yet reported Novo Nordisk A/S 189 participants Est. completion 2025-12-22 50 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT06333080
The Effect of Adherence to Oral Semaglutide on Glycaemic Control in People With Type 2 Diabetes Treated With Metformin
Aalborg University Hospital 1 participants Est. completion 2025-07-29 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT06339086
Efficacy and Safety of Semaglutide Injection in Subjects With Type 2 Diabetes
Not yet reported Chengdu Brilliant Pharmaceutical Co., Ltd. 478 participants Est. completion 2025-12-30 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT06344247
Comparison of the Efficacy and Safety of SGLT2i and GLP-1 Receptor Agonists in Obese Patients With Kidney Disease
Not yet reported RenJi Hospital 48 participants Est. completion 2025-12-01 1 site Stand-aloneChronic kidney disease Other conditions: ObesityView official trial listing → -
Completed NCT NCT06351748
Real-world Study of CHina Ozempic cLinicAl pRactice in Patients With Type 2 Diabetes (SCHOLAR)
Novo Nordisk A/S 34238 participants Est. completion 2024-03-29 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT06354101
The Purpose of This Registry Study is to Learn More About Metabolic Health: Approximately 15,000 Participants Who Are Overweight or Have Obesity With or Without Metabolic Diseases Are Expected to Participate in This Registry Study.
CorEvitas Est. completion 2023-07-01Other conditions: Metabolic HealthView official trial listing → -
Status unknown NCT NCT06361823
Exploratory Study on the Efficacy and Safety of Semaglutide for Idiopathic Intracranial Hypertension Treatment
Not yet reported Capital Medical University 74 participants Est. completion 2025-01-01 Stand-aloneOther conditions: Idiopathic Intracranial HypertensionView official trial listing → -
Completed NCT NCT06363487
Semaglutide and Cognition in Healthy Volunteers
Not yet reported University of Oxford 70 participants Est. completion 2024-12-11 1 siteOther conditions: Cognitive ChangeView official trial listing → -
Completed NCT NCT06388187
A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight
Not yet reported Novo Nordisk A/S 300 participants Est. completion 2026-04-22 25 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT06390501
The Effect of Weekly Semaglutide Treatment on Energy Expenditure
Not yet reported Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences 60 participants Est. completion 2025-09-15 1 site Stand-aloneOther conditions: Obesity; DrugView official trial listing → -
Completed NCT NCT06400615
Study That Tests AD109 in Patients Taking GLP-1 Drugs
Not yet reported Apnimed 40 participants Est. completion 2024-12-26 4 sitesObstructive sleep apneaView official trial listing → -
Completed NCT NCT06401746
Body Surface Gastric Mapping in Patients on Semaglutide
University of Western Sydney 9 participants Est. completion 2025-06-01 1 siteOther conditions: Semaglutide-Induced Gastric Motility, GastroparesisView official trial listing → -
Completed NCT NCT06409130
Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease
Not yet reported Novo Nordisk A/S 270 participants Est. completion 2026-01-12 102 sites Stand-aloneOther conditions: Alcohol-related Liver DiseaseView official trial listing → -
Active, not recruiting NCT NCT06420739
The Semaglutide Study
University Health Network, Toronto 100 participants Est. completion 2026-03-31 1 siteOther conditions: FastingView official trial listing → -
Status unknown NCT NCT06422624
A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects
Not yet reported Bostal Drug Delivery Co., Ltd 14 participants Est. completion 2024-11 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT06426446
Monitoring Patients With Severe Obesity Treated With Wegovy® Using Connected Device: Real-world Data
Not yet reported Assistance Publique - Hôpitaux de Paris 80 participants Est. completion 2025-06-01 1 siteOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT06449235
Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh
Not yet reported Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders 938 participants Est. completion 2025-06 1 siteOther conditions: Type2diabetesView official trial listing → -
Not yet recruiting NCT NCT06449625
Semaglutide in Auto-HSCT
Not yet reported Klaus Gottlob Müller 40 participants Est. completion 2027-02-01Other conditions: Intestinal Mucositis, Inflammation, Chemotherapeutic ToxicityView official trial listing → -
Active, not recruiting NCT NCT06467604
CRAVE Study: Comparing Craving Responses and Diet Quality of GLP1 Receptor Agonist Users
University of California, Davis 7 participants Est. completion 2027-04-01 1 siteOther conditions: ObesityView official trial listing → -
Withdrawn NCT NCT06468748
The Effects of Semaglutide on Body Composition and Performance in Military Personnel
Not yet reported United States Army Research Institute of Environmental Medicine Est. completion 2025-03-27 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT06475586
Effect of Semaglutide on the Psoriatic Lesions in Patients With Type 2 Diabetes Mellitus
Not yet reported University of Banja Luka 30 participants Est. completion 2024-06-10 1 site Stand-aloneOther conditions: Psoriasis Vulgaris, Diabetes Type 2View official trial listing → -
Completed NCT NCT06478550
A Research Study to Understand How People With Type 2 Diabetes Take Ozempic® and if the Ozempic®App Helps Them Stay on This Treatment
Novo Nordisk A/S 304 participants Est. completion 2025-04-23 6 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06489457
The Effects of Semaglutide vs Testosterone Replacement Therapy on Functional Hypogonadism and Sperm Quality in Men With Type 2 Diabetes Mellitus and Obesity
Not yet reported University Medical Centre Ljubljana 25 participants Est. completion 2023-06-30 1 site Stand-aloneType 2 diabetes Other conditions: Obesity, Functional HypogonadismView official trial listing → -
Completed NCT NCT06492330
Efficacy and Safety of CS0159 Combined With Semaglutide in MASH Patients With Obesity and T2DM
Not yet reported Shanghai Jiao Tong University School of Medicine 62 participants Est. completion 2025-04-22 1 siteMASHType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT06497049
Open Randomized Study of Comparative Pharmacokinetics and Biosimilarity of GP40221 (GEROPHARM LLC, Russia) and Ozempic®.
Not yet reported Geropharm 120 participants Est. completion 2024-05-05 1 siteOther conditions: Pharmacokinetics, Safety Issues, BioequivalenceView official trial listing → -
Completed NCT NCT06500143
Residual Gastric Content After Holding of Glucagon-like Peptide-1 Receptor Agonists Before Elective Surgery
Ciusss de L'Est de l'Île de Montréal 94 participants Est. completion 2025-02-28 1 siteOther conditions: Gastric RetentionView official trial listing → -
Completed NCT NCT06500429
A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants Receiving a Glucagon-like Peptide-1 (GLP-1) Agonist
Not yet reported Neurogastrx, Inc. 120 participants Est. completion 2024-09-13 1 site Stand-aloneOther conditions: Overweight and Obesity, HealthyView official trial listing → -
Completed NCT NCT06507475
Real World Effectiveness of Oral Semaglutide in Thailand Participants With Type 2 Diabetes
Novo Nordisk A/S 209 participants Est. completion 2024-12-20 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06533527
Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy
Not yet reported The Cleveland Clinic 69 participants Est. completion 2025-05-20 2 sitesType 2 diabetes Other conditions: Obesity, GastroparesisView official trial listing → -
Completed NCT NCT06534411
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both
Not yet reported Novo Nordisk A/S 1023 participants Est. completion 2026-07-09 163 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT06541509
Mechanisms of Semaglutide Therapy in Heart Failure Patients
Not yet reported, Not yet reported University Medical Centre Ljubljana 10 participants Est. completion 2025-09-01 3 sites Stand-aloneHeart failure Other conditions: ObesityView official trial listing → -
Status unknown NCT NCT06557811
Effect of Oral Semaglutide on Epicardial and Pericoronary Adipose Tissues in Type 2 Diabetes After Myocardial Infarction
Not yet reported University of Sao Paulo General Hospital 88 participants Est. completion 2026-09-01 1 siteCardiovascular disease Other conditions: Diabetic PatientsView official trial listing → -
Active, not recruiting NCT NCT06571383
STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight Loss
Not yet reported Novo Nordisk A/S 500 participants Est. completion 2031-11-15 93 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT06579105
Efficacy, Safety, and Tolerability of Once Daily Oral Administration of AZD5004 Versus Placebo for 26 Weeks in Adults With Type 2 Diabetes Mellitus.
Not yet reported AstraZeneca 406 participants Est. completion 2025-12-19 97 sitesType 2 diabetesView official trial listing → -
Enrolling by invitation NCT NCT06581120
GLP_1 RA Ultrasound Study
Children's Hospital Medical Center, Cincinnati 100 participants Est. completion 2026-07 1 siteOther conditions: Glucagon Like Peptide-1 (GLP-1, Delayed Gastric Emptying, Risk of Aspiration, Diabetes, Morbid ObesityView official trial listing → -
Completed NCT NCT06584916
A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)
Not yet reported Eli Lilly and Company 376 participants Est. completion 2025-11-21 29 sitesOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT06604624
Semaglutide in Treatment of Obesity
Not yet reported CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. 462 participants Est. completion 2025-09-24 1 siteOther conditions: Weight ManagementView official trial listing → -
Completed NCT NCT06608433
Glucagon-like Peptide-1 Receptor Agnoists for the Assessment of Adrenal Function
Not yet reported University Hospital, Basel, Switzerland 22 participants Est. completion 2025-11-30 1 site Stand-aloneOther conditions: Healthy Volunteer Study, HPA, Cortisol Deficiency, Adrenal InsufficiencyView official trial listing → -
Not yet recruiting NCT NCT06616961
Efficacy and Safety of Semaglutide for Weight Loss in Overweight or Obese Adults in Bangladesh With or Without Type 2 Diabetes Mellitus
Not yet reported Popular Medical College Hospital 480 participants Est. completion 2026-10 1 site Stand-aloneType 2 diabetes Other conditions: ObesityView official trial listing → -
Withdrawn NCT NCT06619015
Tailoring Obesity Treatment Trial
Not yet reported, Not yet reported Esbjerg Hospital - University Hospital of Southern Denmark Est. completion 2025-04-01 1 site Stand-alonePrediabetes Other conditions: Obesity, Appetite RegulationView official trial listing → -
Completed NCT NCT06629688
Semaglutide and Intestinal Iron Absorption
Not yet reported University Hospital Dubrava 51 participants Est. completion 2024-04-01 1 site Stand-aloneType 2 diabetes Other conditions: Iron AbsorptionView official trial listing → -
Completed NCT NCT06634927
Pharmacokinetic Similarity, Safety, and Immunogenicity of Semaglutide Injection and Ozempic ® Injection in Healthy Subjects.
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 68 participants Est. completion 2025-02-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06640972
Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists
Not yet reported Response Pharmaceuticals 68 participants Est. completion 2025-05-13 1 siteOther conditions: Triglycerides, Weight Gain Trajectory, Cholesterol, ElevatedView official trial listing → -
Completed NCT NCT06642584
A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation IV
Not yet reported Novo Nordisk A/S 90 participants Est. completion 2025-08-13 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06649344
A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 Diabetes
Not yet reported Fujian Shengdi Pharmaceutical Co., Ltd. 884 participants Est. completion 2026-07-18 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06659679
Emulating the PIONEER6 Diabetes Trial Using Healthcare Claims
Brigham and Women's Hospital 26126 participants Est. completion 2025-03-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06659718
Emulation of the SOUL Diabetes Trial in Healthcare Claims
Brigham and Women's Hospital 43650 participants Est. completion 2025-02-13 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06691243
Evaluation Of Semaglutide in Adults With Cocaine Use Disorder With and Without HIV
Not yet reported University of Maryland, Baltimore 40 participants Est. completion 2027-07 2 sites Stand-aloneOther conditions: Cocaine Use Disorder, HIVView official trial listing → -
Completed NCT NCT06699329
A Study of Enlicitide Decanoate (MK-0616) and Semaglutide in Healthy Adult Participants (MK-0616-023)
Not yet reported Merck Sharp & Dohme LLC 38 participants Est. completion 2024-05-24 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Active, not recruiting NCT NCT06715514
Menopausal Hormone Therapy, GLP-1 Agonists, and Glucose and Energy Homeostasis in Postmenopausal Women With Diabetes
Not yet reported Lia Bally 96 participants Est. completion 2026-12-31 1 siteType 2 diabetes Other conditions: MenopauseView official trial listing → -
Completed NCT NCT06716307
A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or Obesity
Not yet reported Novo Nordisk A/S 18 participants Est. completion 2025-03-28 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT06738979
A Clinical Study Comparing Semaglutide Injection and Wegovy® for Weight Management in Obese Subjects
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 408 participants Est. completion 2026-08 66 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT06754163
Evaluating the Effect of the STEP@STAH Semaglutide Protocol on the Physical Health Measures of Atypical Antipsychotic-Treated Patients
Not yet reported St Andrew's Healthcare 20 participants Est. completion 2027-12-30 1 siteOther conditions: Obesity and Obesity-related Medical Conditions, Psychiatric DisordersView official trial listing → -
Completed NCT NCT06761703
A Study to Determine the Feasibility of Online Recruitment of People Using an Anti-Obesity Medication for Weight Loss
Amgen 200 participants Est. completion 2025-01-06 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT06762314
Efficacy and Safety of Empagliflozin or Semaglutide in Overweight/Obese Patients With Type 1 Diabetes
Not yet reported Mostafa Bahaa 114 participants Est. completion 2026-01-20 1 siteOther conditions: DiabetesView official trial listing → -
Not yet recruiting NCT NCT06764056
Characterization and Management of Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)
Not yet reported Institut universitaire de cardiologie et de pneumologie de Québec, University Laval 120 participants Est. completion 2026-05 1 siteMASH Other conditions: Metabolic Associated Fatty Liver Disease, ObesityView official trial listing → -
Active, not recruiting NCT NCT06778967
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus
Not yet reported Gan & Lee Pharmaceuticals. 1100 participants Est. completion 2026-12-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06779929
Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes
Brigham and Women's Hospital 70000 participants Est. completion 2026-03-01 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06780449
A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity
Not yet reported Novo Nordisk A/S 400 participants Est. completion 2028-10-31 36 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT06788626
Glucagon-like Peptide 1 Receptor Agonist in Acute Large Vessel Occlusion Stroke After Endovascular Treatment
Not yet reported Wei Hu 390 participants Est. completion 2028-02 1 site Stand-aloneCardiovascular disease Other conditions: Large Vessel Occlusion, Neuroprotective Drugs, Endovascular TreatmentView official trial listing → -
Completed NCT NCT06797869
A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral Neuropathy
Not yet reported Novo Nordisk A/S 142 participants Est. completion 2026-08-05 55 sites Stand-aloneType 2 diabetes Other conditions: Diabetic Peripheral NeuropathyView official trial listing → -
Active, not recruiting NCT NCT06801015
Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor Functions
Not yet reported Mayo Clinic 30 participants Est. completion 2028-03-31 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT06803888
Bariatric Surgery vs. Semaglutide vs. Tirzepatide
Not yet reported Ali Aminian 140 participants Est. completion 2027-12-01 1 siteOther conditions: Obesity and Obesity-related Medical ConditionsView official trial listing → -
Completed NCT NCT06804603
A Study to Measure the Effects of Using Tradipitant on Nausea and Vomiting After GLP-1R Agonist Use
Not yet reported Vanda Pharmaceuticals 124 participants Est. completion 2025-10-06 3 sitesOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT06807970
Optimization of Obesity for Total Knee Replacement With Glucagon-like Peptide-1 Receptor Agonist
Not yet reported The University of Hong Kong 54 participants Est. completion 2028-07-01 1 siteOsteoarthritisView official trial listing → -
Active, not recruiting NCT NCT06814938
A Study of a Novel Precision Medicine Approach For Obesity
Not yet reported Mayo Clinic 135 participants Est. completion 2028-11 2 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT06820047
Sleeve Gastrectomy vs. Lifestyle & Medications: Impact on BMI Trajectory and Target Attainment in a Matched Cohort Study
University of Roma La Sapienza 190 participants Est. completion 2024-07-01 2 sitesOther conditions: Obesity and Obesity-related Medical ConditionsView official trial listing → -
Not yet recruiting NCT NCT06825793
Semaglutide's Weight Loss Effects in Obesity
Not yet reported Beijing Chao Yang Hospital 56 participants Est. completion 2027-12-31Other conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT06827002
Effect of Aqueous Extracts of Cissus Quadrangularis and Dichrostachys Glomerata on GLP-1 Concentration and DPP-4 Activity in Overweight and Obese Adults
Not yet reported, Not yet reported University of Yaounde 1 248 participants Est. completion 2026-08 1 siteOther conditions: Obesity and Overweight, Appetite RegulationView official trial listing → -
Completed NCT NCT06851962
Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.
Not yet reported Fundación para la Investigación del Hospital Clínico de Valencia 92 participants Est. completion 2026-06-30 3 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06856928
Impact of Antiobesity Medications on Appetite and Appetite-related Hormones and Metabolites.
University of Colorado, Denver 16 participants Est. completion 2027-12Other conditions: Obesity; DrugView official trial listing → -
Completed NCT NCT06874751
Semaglutide Effects on Cardiovascular Outcomes in People With Overweight or Obesity in the Real World
Novo Nordisk A/S 45456 participants Est. completion 2025-03-28 1 site Stand-aloneCardiovascular disease Other conditions: Overweight, ObesityView official trial listing → -
Active, not recruiting NCT NCT06884293
A Study Comparing IBI362 vs Semaglutide in Chinese Overweight or Obese Adults With Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD)
Not yet reported Innovent Biologics (Suzhou) Co. Ltd. 479 participants Est. completion 2027-06-30 1 siteOther conditions: Overweight, Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD)View official trial listing → -
Not yet recruiting NCT NCT06909006
Semaglutide Treatment in Type 1 Diabetes
Not yet reported Nordsjaellands Hospital 122 participants Est. completion 2028-06 1 siteOther conditions: Obesity in Diabetes, Obesity/Therapy, Type 1 Diabetes Mellitus (T1DM), Insulin Sensitivity/Resistance, Semaglutide, Lipidomics, Metabolomics, Weight Loss, Glycemic Control for Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT06913023
Semaglutide for the Prevention Of Post-Transplant Diabetes Mellitus
Not yet reported, Not yet reported University Health Network, Toronto 74 participants Est. completion 2027-11-30 2 sites Stand-aloneOther conditions: Kidney Transplant RecipientView official trial listing → -
Completed NCT NCT06914102
Emulation of the STEP-HFpEF DM Heart Failure Trial in Healthcare Claims Data
Brigham and Women's Hospital 58387 participants Est. completion 2025-06-01 1 siteType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT06914141
Comparative Effectiveness of Tirzepatide Versus Semaglutide in Individuals With Heart Failure With Preserved Ejection Fraction
Brigham and Women's Hospital 28118 participants Est. completion 2025-06-01 1 siteType 2 diabetesHeart failureView official trial listing → -
Not yet recruiting NCT NCT06946628
New Triple Therapy in Newly Diagnosed Type 2 Diabetes
Not yet reported Sun Yat-sen University 296 participants Est. completion 2030-12-31 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT06950684
Impact of Protein Supplementation and Resistance Training on Body Composition, Functional Parameters, Metabolic Adaptation, and Nitrogen Balance in Adults Aged 45 Years and Older With Overweight or Obesity Receiving Incretin-based Medications
Not yet reported Assuta Medical Center 180 participants Est. completion 2028-07-01Other conditions: Obesity, Overweight (BMI > 25), Weight LossView official trial listing → -
Enrolling by invitation NCT NCT06954090
Urinary Proteomics to Guide Early Intervention to Prevent Complications in Type 2 Diabetes - a Feasibility Study
Not yet reported Steno Diabetes Center Copenhagen 50 participants Est. completion 2027-05-31 1 siteChronic kidney disease Other conditions: Type 2 DM, AlbuminuriaView official trial listing → -
Completed NCT NCT06972992
A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC47 in Combination With Semaglutide
Not yet reported Ascletis Pharma (China) Co., Limited 28 participants Est. completion 2025-09-22 1 site Stand-aloneOther conditions: Chronic Weight ManagementView official trial listing → -
Completed NCT NCT06974825
A Study of BGM0504 in Chinese Patients With Type 2 Diabetes
Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 67 participants Est. completion 2024-08-13 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06977438
GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way Forward
Not yet reported University of Minnesota 1020 participants Est. completion 2032-01-31 1 site Stand-aloneOther conditions: Obesity, ChildhoodView official trial listing → -
Active, not recruiting NCT NCT06980623
Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction
Brigham and Women's Hospital 26000 participants Est. completion 2026-10-01 1 siteType 2 diabetesHeart failureView official trial listing → -
Active, not recruiting NCT NCT06982859
A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 95 participants Est. completion 2026-12 1 siteOther conditions: Diabetes Mellitus, Insulin SensitivityView official trial listing → -
Active, not recruiting NCT NCT06983171
Semaglutide Effectiveness in Patients With Metabolic Dysfunction-Associated Fatty Liver Disease in the Real World Practice
Center of target therapy 70 participants Est. completion 2028-09-12 1 siteOther conditions: MAFLDView official trial listing → -
Not yet recruiting NCT NCT06987669
Gastric Emptying in Healthy Volunteers and GLP-1 Agonist Users
Clinica Alemana de Santiago 155 participants Est. completion 2027-12-31Other conditions: Diabetes Type 2, Obesity and OverweightView official trial listing → -
Active, not recruiting NCT NCT07011667
A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term
Not yet reported Novo Nordisk A/S 609 participants Est. completion 2028-10-17 46 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Enrolling by invitation NCT NCT07018544
A Multicentre, Prospective, Single-arm, Non-interventional Regulatory Post-marketing Surveillance (rPMS) Study to Investigate the Safety and Effectiveness of Wegovy® (Semaglutide) in Patients With Obesity and Patients With Overweight in Routine Clinical Practice in Korea
Novo Nordisk A/S 840 participants Est. completion 2027-02-28 8 sitesOther conditions: Obesity and OverweightView official trial listing → -
Not yet recruiting NCT NCT07021937
Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity
Not yet reported University of Colorado, Denver 120 participants Est. completion 2031-04-30 1 siteOther conditions: Obesity/TherapyView official trial listing → -
Not yet recruiting NCT NCT07027969
Metabolic Surgery for Atrial Fibrillation Elimination
Not yet reported Ali Aminian 100 participants Est. completion 2030-03-31 1 siteOther conditions: Atrial Fibrillation, Obesity and Obesity-related Medical ConditionsView official trial listing → -
Not yet recruiting NCT NCT07035704
Prevent and Reverse Obesity in Children, Adolescents and Young Adults
Not yet reported piero portincasa 200 participants Est. completion 2027-03-30 1 siteOther conditions: Overweight (BMI > 25)View official trial listing → -
Enrolling by invitation NCT NCT07041983
24-h Energy Expenditure and Anti-obesity Medication
University of Pisa 30 participants Est. completion 2026-12-01 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT07043361
Efficacy of Semaglutide in Glycemic Control, Weight Loss, and Improving Lipidogram- Role of Baseline Vitamin D Levels
Hillel Yaffe Medical Center 5300 participants Est. completion 2025-04-30 1 siteOther conditions: Metabolic DiseaseView official trial listing → -
Not yet recruiting NCT NCT07046273
Phase III Clinical Study on the Efficacy and Safety of Semaglutide and Ozempic® in Patients With Type 2 Diabetes
Not yet reported Shandong New Time Pharmaceutical Co., LTD 496 participants Est. completion 2029-02-01Type 2 diabetesView official trial listing → -
Enrolling by invitation NCT NCT07055607
A Two-year Prospective, Observational Study of Wegovy in Real-world Clinical Practice
Novo Nordisk A/S 1250 participants Est. completion 2028-08-15 30 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT07056803
Oral vs. Subcutaneous Semaglutide in Type 2 Diabetes Mellitus
University of Palermo 212 participants Est. completion 2025-06-25 1 siteType 2 diabetesView official trial listing → -
Enrolling by invitation NCT NCT07057310
Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women
Not yet reported Mayo Clinic 30 participants Est. completion 2027-03-31 1 siteOther conditions: Obesity, MenopauseView official trial listing → -
Not yet recruiting NCT NCT07073053
The Role of Glucagon-Like Peptide-1 Receptor Agonists in Coronary Artery Diseases and Their Potential Mechanisms
Not yet reported Taipei Veterans General Hospital, Taiwan 60 participants Est. completion 2028-07-31 1 site Stand-aloneType 2 diabetes Other conditions: Glucagon-Like Peptide-1 Receptor Agonists, Coronary Arterial Disease (CAD)View official trial listing → -
Active, not recruiting NCT NCT07073417
A Study to Compare XW003 Injection and Semaglutide Injection in Chinese Adults With Obesity (SLIMMER-UP-SWITCH)
Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 163 participants Est. completion 2027-08-23 1 siteOther conditions: Obesity, Weight ManagementView official trial listing → -
Terminated NCT NCT07081178
A Non-interventional Study Investigating Semaglutide in Combination With Lifestyle-based Modifications for the Management of Obesity in Real-World Clinical Practice in Germany (WeGo Real Germany).
Novo Nordisk A/S 100 participants Est. completion 2025-12-18 1 siteOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT07087795
A Study to See the Effect of NNC0194-0499 Alone or in Combination With Semaglutide on Blood Sugar Control in People Living With Type 1 Diabetes
Not yet reported Novo Nordisk A/S 96 participants Est. completion 2026-09-25 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Not yet recruiting NCT NCT07090343
Semaglutide in Patients Undergoing Transcatether Aortic Valve Replacement
Not yet reported Leiden University Medical Center 826 participants Est. completion 2031-04-01Heart failure Other conditions: Aortic StenosisView official trial listing → -
Enrolling by invitation NCT NCT07092605
Effectiveness of Microdosed GLP-1 in Improving Health, Quality of Life, and Longevity Measures
Not yet reported AgelessRx 150 participants Est. completion 2025-12-01 1 siteOther conditions: Longevity, Quality of Life, Mood, Inflammation, Immune Health, Pain Management, Weight Management, AlertnessView official trial listing → -
Completed NCT NCT07096063
Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular Risk
Brigham and Women's Hospital 887132 participants Est. completion 2025-07-15 1 siteType 2 diabetes Other conditions: Overweight, Cardiovascular (CV) RiskView official trial listing → -
Completed NCT NCT07096739
Tolerance of a High Protein Nutrition Shake in Individuals on GLP-1
Not yet reported Kate Farms Inc 20 participants Est. completion 2025-09-19 1 siteOther conditions: GLP-1 ConcentrationView official trial listing → -
Active, not recruiting NCT NCT07112872
A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes
Not yet reported Hoffmann-La Roche 240 participants Est. completion 2026-11-27 50 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07115069
Comparison of Body Composition Changes With Weight Loss Interventions
Vanderbilt University Medical Center 60 participants Est. completion 2027-12 1 siteOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07135245
Improved Treatment and Monitoring of Alzheimer's Disease
Not yet reported Rune Skovgaard Rasmussen 180 participants Est. completion 2031-09-30 Stand-aloneOther conditions: Alzheimer Disease (AD)View official trial listing → -
Not yet recruiting NCT NCT07139548
A Study of RAY1225 Versus Semaglutide as Add-on Therapy to Oral Antidiabetic Drugs in Participants With Type 2 Diabetes
Not yet reported Guangdong Raynovent Biotech Co., Ltd 600 participants Est. completion 2026-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07141914
A Master Protocol for Semaglutide Effects on Cardiovascular and Obesity-related Outcomes in People With Overweight or Obesity in the Real World
Novo Nordisk A/S 285327 participants Est. completion 2025-12-19 1 siteHeart failureCardiovascular disease Other conditions: Overweight, Obesity, Primary PreventionView official trial listing → -
Not yet recruiting NCT NCT07152756
Impact of a One-Week Discontinuation of Semaglutide on Gastric Retention and Endoscopic Mucosal Visibility Scores
Fudan University 418 participants Est. completion 2028-09-15 1 siteOther conditions: Gastric RetentionView official trial listing → -
Enrolling by invitation NCT NCT07154238
Characteristics and Treatment Experiences of Individuals Using Injectable Semaglutide for Weight Management, a Cross-sectional Time-series Analysis, Multi-country Study.
Novo Nordisk A/S 2546 participants Est. completion 2026-09-30 1 siteOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07156331
Research on Effects of Drugs on Body Composition and Function With Imaging in Diabetes
Kristin Clemens 20 participants Est. completion 2027-12-31Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07156591
Impact of Neuropathy on the Risk of Semaglutide-Induced Gastric Retention
Fudan University 460 participants Est. completion 2028-09-15 1 siteOther conditions: Gastric RetentionView official trial listing → -
Completed NCT NCT07163624
UBT251 Injection Phase II (Type 2 Diabetes Mellitus) Study
Not yet reported The United Bio-Technology (Hengqin) Co., Ltd. 211 participants Est. completion 2025-12-30 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07165158
The Effect of Semaglutide on Bone Health
Not yet reported The First Affiliated Hospital of Xiamen University 150 participants Est. completion 2026-12-31 1 site Stand-aloneType 2 diabetes Other conditions: Osteoporosis, Osteoporosis FractureView official trial listing → -
Withdrawn NCT NCT07172867
A Ph2 Study to Evaluate the Safety, Efficacy and Tolerability of HT-6184 and Semaglutide in Obese Participants With T2DM
Not yet reported Halia Therapeutics, Inc. Est. completion 2026-01-23 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07179120
Can Fat-Burning Shots Boost Fertility? Comparing Weight-Loss Injections vs. Healthy Habits for Obese Men With Low Sperm Health
Not yet reported First Affiliated Hospital of Wenzhou Medical University 180 participants Est. completion 2027-01-02 Stand-aloneOther conditions: Obesity-related Male InfertilityView official trial listing → -
Active, not recruiting NCT NCT07184086
A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet
Not yet reported Novo Nordisk A/S 80 participants Est. completion 2028-02-09 2 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07187856
Phase 2 Randomized Study of PG-102 vs Placebo and Semaglutide in Type 2 Diabetes Mellitus
Not yet reported ProGen. Co., Ltd. 80 participants Est. completion 2026-12 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07188545
Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)
Ohio State University 23280000 participants Est. completion 2029-06-30 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT07190144
Coronary Flow Reserve Changes After Semaglutide Treatment
Ekrem Bilal Karaayvaz 122 participants Est. completion 2025-08-01 1 siteOther conditions: The Study Focused on the Vascular Effects of Semaglutide in Both Diabetic and Non-diabetic Patients, Obesity &Amp; OverweightView official trial listing → -
Not yet recruiting NCT NCT07200622
Oral Semaglutide in Patients With Alzheimer's Disease
Not yet reported Imperial College London 60 participants Est. completion 2028-12-31Other conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT07216651
WeDosify Real World Evidence (RWE) Study: Personalized Semaglutide Dosing in U.S. Adults
Closed Loop Medicine 20 participants Est. completion 2026-03-18 1 siteOther conditions: Obesity & OverweightView official trial listing → -
Active, not recruiting NCT NCT07220629
Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide in Participants With Obesity (RESOLVE-2)
Not yet reported NodThera Limited 82 participants Est. completion 2026-08-21 9 sitesOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07249554
Combination Therapy for Alcohol Use Disorder
Not yet reported Johns Hopkins University 45 participants Est. completion 2028-09 1 siteAlcohol use disorderView official trial listing → -
Not yet recruiting NCT NCT07251556
GLP-1 Receptor Agonists in Non-diabetic Patients With Psoriatic Arthritis
Not yet reported Chinese University of Hong Kong 40 participants Est. completion 2027-01-01Other conditions: Psoriasis ArthritisView official trial listing → -
Completed NCT NCT07271251
A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 267 participants Est. completion 2026-08-04 15 sitesType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07276763
Impact of Discontinuing GLP-1 Receptor Agonists for Two Weeks Prior to Upper Endoscopy on the Risk of Gastric Retention
Fudan University 16509 participants Est. completion 2025-12-15 1 siteOther conditions: Gastric RetentionView official trial listing → -
Enrolling by invitation NCT NCT07280221
WEgovy Real World Assessment of Weight Loss in Korea
Novo Nordisk A/S 500 participants Est. completion 2027-10-31 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT07280403
Effect of a Low-carbohydrate Diet on Weight Loss in People Using the Injectable GLP-1 Agonist Semaglutide for Weight Loss
Not yet reported INQUIS Clinical Research 60 participants Est. completion 2025-11-30 1 siteOther conditions: Weight LossView official trial listing → -
Completed NCT NCT07281196
Semaglutide Effects on Sleep Apnea in Patients With Type 2 Diabetes/Obesity and Comorbid Obstructive Sleep Apnea
Shanghai Fengxian District Central Hospital 15 participants Est. completion 2026-01-31 1 siteObstructive sleep apneaView official trial listing → -
Not yet recruiting NCT NCT07282769
Semaglutide (Wegovy) Treatment for Trichotillomania
Not yet reported University of Chicago 10 participants Est. completion 2027-02Other conditions: Trichotillomania (Hair-Pulling Disorder), Trichotillomania, Hair Pulling Disorder, Hair Pulling, Hair-Pulling DisorderView official trial listing → -
Active, not recruiting NCT NCT07285902
A Study Comparing the Efficacy and Safety of HRS9531 Injection With Semaglutide Injection in Subjects With Obesity
Not yet reported Fujian Shengdi Pharmaceutical Co., Ltd. 572 participants Est. completion 2027-03 2 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT07297238
Effect of GLP-1 on Intestinal Barrier Function in SBS-IF Patients: A Preliminary Exploration.
Not yet reported Jinling Hospital, China 20 participants Est. completion 2026-06-30 2 sites Stand-aloneOther conditions: Short Bowel Syndrome (SBS), Intestinal FailureView official trial listing → -
Not yet recruiting NCT NCT07319975
Effect of Semaglutide and Tirzepatide Combined With Exercise in Obesity
Not yet reported Istanbul Galata University 48 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07323134
The Effect of Semaglutide on the Intestinal Flora in Obesity
Beijing Chao Yang Hospital 40 participants Est. completion 2026-08-01Other conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT07325435
Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor Agonists
Not yet reported MaryAnn Banerji 60 participants Est. completion 2028-06-30 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT07357740
A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S Est. completion 2027-10-13 61 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT07357766
A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body Weight
Not yet reported Novo Nordisk A/S Est. completion 2028-01-17 116 sites Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT07368855
GLP-1 Medicines and Mental Health Changes
Not yet reported University of California, San Diego 90 participants Est. completion 2025-07-01 1 siteOther conditions: Obesity, Depression, GLP-1View official trial listing → -
Not yet recruiting NCT NCT07382388
A Real-World Study on the Impact of Weight Loss on Treatment Efficacy in Overweight/Obese Patients With Plaque Psoriasis
Peking University Third Hospital 70 participants Est. completion 2027-12-31Other conditions: PsoriasisView official trial listing → -
Not yet recruiting NCT NCT07389941
Semaglutide PrIor to CathEeter Ablation in Patients With Atrial Fibrillation
Not yet reported University of Luebeck 240 participants Est. completion 2029-04 Stand-aloneOther conditions: Atrial Fibrillation (AF)View official trial listing → -
Active, not recruiting NCT NCT07390110
Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)
Brigham and Women's Hospital 25664 participants Est. completion 2026-06-30 1 siteType 2 diabetesHeart failureView official trial listing → -
Not yet recruiting NCT NCT07391267
Pathogenesis of Chronic Kidney Disease Associated With Metabolic Dysfunction- Associated Fatty Liver Disease (MAFLD) and Treatment Response of Oral Semaglutide.
Not yet reported Institute of Liver and Biliary Sciences, India 90 participants Est. completion 2028-12-31 1 siteChronic kidney disease Other conditions: MAFLDView official trial listing → -
Not yet recruiting NCT NCT07392151
Reversal to Normoglycemia by Treating Prediabetes
Not yet reported Michael Mæng 158 participants Est. completion 2029-10 1 sitePrediabetes Other conditions: Chronic Coronary SyndromeView official trial listing → -
Not yet recruiting NCT NCT07400107
AMAZE 8: A Research Study Investigating How Well the Medicine NNC0487-0111 Compared to Semaglutide Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
Not yet reported Novo Nordisk A/S 1000 participants Est. completion 2029-01-26 120 sites Stand-aloneType 2 diabetes Other conditions: Obesity, OverweightView official trial listing → -
Not yet recruiting NCT NCT07411378
Testing the Efficacy, Safety, and PK of 20E in Patients With Obesity Who Are Starting Treatment With the GLP-1 Agonist Semaglutide for Weight Loss.
Not yet reported Biophytis 164 participants Est. completion 2027-08 Stand-aloneOther conditions: Muscle Wasting, Obesity & Overweight, ObesityView official trial listing → -
Completed NCT NCT07417618
INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)
Brigham and Women's Hospital 60000 participants Est. completion 2026-06-19 1 siteType 2 diabetesCardiovascular disease Other conditions: OverweightView official trial listing → -
Not yet recruiting NCT NCT07423481
Weight Trajectories and Predictive Factors After Semaglutide in Patients With Grade 3 and Complicated Obesity
Nantes University Hospital 3000 participants Est. completion 2027-03-01 1 siteOther conditions: Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07424430
Real-world Canadian Retrospective Study Evaluating Longitudinal Semaglutide Use on Cardio-Kidney-Metabolic Outcomes
LMC Diabetes & Endocrinology Ltd. 400 participants Est. completion 2026-05Type 2 diabetes Other conditions: Diabetes (DM), Obesity (Disorder)View official trial listing → -
Not yet recruiting NCT NCT07430059
Safety, Tolerability and Pharmacokinetics of a Subcutaneous Semaglutide Implant
Not yet reported Vivani Medical, Inc 20 participants Est. completion 2027-01 Stand-aloneOther conditions: Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07430332
GLP-1 RA for Stage 1 Type 1 Diabetes
Not yet reported Children's Hospital Medical Center, Cincinnati 15 participants Est. completion 2030-01-01 1 site Stand-aloneOther conditions: Stage 1 Diabetes Mellitus, Type 1View official trial listing → -
Not yet recruiting NCT NCT07444073
Assessing Biological Aging in a Real-World Medical Weight Loss Program Using the LinAge2 Clinical Clock
National University of Singapore 440 participants Est. completion 2027-12-31 2 sitesOther conditions: Aging, Obesity & OverweightView official trial listing → -
Enrolling by invitation NCT NCT07456774
A Two-armed Real-world Study of Ozempic (OW Semaglutide) to Evaluate Its Adherence and Persistence Compared With Other Anti-diabetic Drugs Among Adult T2DM Patients in China
Novo Nordisk A/S 100000 participants Est. completion 2026-08-31 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07457424
Direct Measurement of Microstructure of Ingestive Behaviour After Initiation of GLP-1 Receptor Agonist Treatment at Maximum Dose (DIGRAT)
University College Dublin 140 participants Est. completion 2027-01-31 1 siteOther conditions: Metabolic Disease, Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07462663
SHAPE-ENDO: Pilot Randomized Trial of Multimodal Pre-Surgical Optimization Versus Standard Surgery in Patients With Obesity and Early-Stage Endometrial Cancer
Not yet reported Hospital Universitari de Bellvitge 80 participants Est. completion 2035-01Other conditions: Endometrial Cancer, Endometrial Cancer Stage I, Atypical Endometrial Hyperplasia and Endometrial Carcinoma Stage I, Atypical Endometrial Hyperplasia, Endometrial Intraepithelial Neoplasia, Obesity & Overweight, BMI>40, Obesity, Obesity Grade IIIView official trial listing → -
Not yet recruiting NCT NCT07478653
MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease
Not yet reported Oelisoa Andriankaja 50 participants Est. completion 2028-07-31 1 siteOther conditions: Obesity, Dental Care for ChildrenView official trial listing → -
Not yet recruiting NCT NCT07483801
DECODE - Haemodynamic Effects Of Semaglutide and Tirzepatide - a Series of Pilot Studies
Not yet reported Cambridge University Hospitals NHS Foundation Trust 112 participants Est. completion 2028-04 1 site MixedCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT07505303
MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) Trial
Not yet reported Eccogene 151 participants Est. completion 2026-10-15 15 sites Stand-aloneOther conditions: Adult Obesity, Weight ManagementView official trial listing → -
Not yet recruiting NCT NCT07509112
Semaglutide for Treatment of People With Methamphetamine Use Disorder: the SHIFT Study
Not yet reported Kirby Institute 40 participants Est. completion 2027-03 5 sites Stand-aloneOther conditions: Methamphetamine Use DisorderView official trial listing → -
Not yet recruiting NCT NCT07511543
Glucagon-like Peptide-1 Receptor Agonists for Endovascular Stroke Thrombectomy
Not yet reported Population Health Research Institute 826 participants Est. completion 2031-12-30 Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT07539584
Adiponectin in Patients With Metabolic Disorders
Not yet reported Moscow Regional Research and Clinical Institute (MONIKI) 130 participants Est. completion 2024-04-08 1 site Stand-aloneType 2 diabetes Other conditions: Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD)View official trial listing → -
Not yet recruiting NCT NCT07547878
Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)
Not yet reported Baylor Research Institute 64 participants Est. completion 2029-03-31 1 siteChronic kidney diseaseType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07554417
Combatting Muscle Loss in Obese Adult Patients on GLP-1 Medications Through Dietary Counseling and Exercise During Treatment Evaluates Whether a 12-week Exercise and Individualized Nutrition Program Can Reduce Muscle and Bone Loss and Improve Strength, Fitness, and Function in Obese Adults on GLP-1
Not yet reported William Marsh Rice University 20 participants Est. completion 2026-08-06 1 site Stand-aloneOther conditions: GLP - 1, Obesity & Overweight, Muscle Loss, Exercise Intervention, Dietary AssessmentView official trial listing → -
Not yet recruiting NCT NCT07588984
GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study
Noom Inc. 2310 participants Est. completion 2029-05 1 siteCardiovascular disease Other conditions: Obesity & Overweight, Weight Loss, Preventative Health, Body WeightView official trial listing → -
Not yet recruiting NCT NCT07592546
Translational Health Research Into Vascular and Neurocognitive Effects of Weight Loss
Not yet reported Alain Dagher 240 participants Est. completion 2030-06-01 1 site Stand-aloneOther conditions: Class I/II ObesityView official trial listing → -
Not yet recruiting NCT NCT07599046
Fecal Microbiota Transplantation (FMT) Combined With Calorie-Restricted Diet and Semaglutide in Patients With Obesity and Type 2 Diabetes
Not yet reported Eighth Affiliated Hospital, Sun Yat-sen University 20 participants Est. completion 2029-12-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07610174
Effects of Dapagliflozin, Semaglutide, and Their Combination in Heart Failure Patients With Prosthetic Heart Valves
Not yet reported Kafrelsheikh University 160 participants Est. completion 2026-04-29 1 site Stand-aloneHeart failure Other conditions: Heart Valve ProsthesisView official trial listing → -
Not yet recruiting NCT NCT07613437
GLP-1 Receptor Agonist in Primary Intracerebral Hemorrhage: A Phase 2 Randomized Trial
Not yet reported Chinese University of Hong Kong 200 participants Est. completion 2028-12-31 3 sitesOther conditions: Intracerebral HemorrhageView official trial listing → -
Not yet recruiting NCT NCT07614412
SHIELD-T1D: Shingrix and GLP-1 Agonist for Beta-Cell Preservation in Recent-Onset Type 1 Diabetes.
Not yet reported Ministry of Health, Saudi Arabia 240 participants Est. completion 2028-12-31 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT07617155
GLP-1 Agonists for Prevention of Recurrent Hypertriglyceridemic Acute Pancreatitis
Not yet reported Peking Union Medical College Hospital 396 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Hypertriglyceridemia Induced Acute Pancreatitis, Recurrent Acute Pancreatitis, Pancreatitis Relapsing, HypertriglyceridemiaView official trial listing → -
Completed NCT NCT07619495
Injectable Semaglutide vs Dulaglutide in Individuals at Cardiovascular Risk
Brigham and Women's Hospital 120000 participants Est. completion 2026-06-01 1 siteType 2 diabetes Other conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT07619508
Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.
Brigham and Women's Hospital 100000 participants Est. completion 2026-06-01 1 siteOther conditions: Obesity, OverweightView official trial listing → -
Not yet recruiting NCT NCT07621640
Brown Adipose Tissue as a Mechanistic Determinant of Semaglutide Treatment Response in Obesity (BAT-Sema Study)
Not yet reported Hallym University 80 participants Est. completion 2031-02 2 sites Stand-aloneMetabolic syndrome Other conditions: Obesity, Brown Adipose TissueView official trial listing → -
Not yet recruiting NCT NCT07622810
BALANCE-OBS: Bofanglutide (GZR18) Versus Semaglutide in Latin American Adults With Overweight or Obesity
Not yet reported Carnot Laboratories 352 participants Est. completion 2027-12 6 sitesOther conditions: Obesity & OverweightView official trial listing → -
Completed NCT NCT07627074
Weight Loss in Adults Using Semaglutide (Real-world Study)
Novo Nordisk A/S 237211 participants Est. completion 2026-06-15 2 sitesOther conditions: Overweight, ObesityView official trial listing → -
Not yet recruiting NCT NCT07627191
GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular Cancer
Not yet reported University of Arizona 30 participants Est. completion 2028-06-30 1 site Stand-aloneOther conditions: Pancreatic Cancer, Colorectal Cancer, Hepatocellular CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07628985
BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes
Not yet reported Carnot Laboratories 374 participants Est. completion 2027-10 7 sitesType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07642635
Glucagon-Like Peptide-1 Receptor Agonists to Attenuate Metabolic Risk in Individuals With Duchenne Muscular Dystrophy
Not yet reported, Not yet reported Vanderbilt University Medical Center 30 participants Est. completion 2030-12 1 site Stand-aloneOther conditions: Duchenne Muscular Dystrophy (DMD)View official trial listing → -
Active, not recruiting NCT NCT07649759
Mindfulness-Based Nutrition Group Therapy as an Adjunct to GLP-1 Treatment of Obesity
Not yet reported Bern University of Applied Sciences 40 participants Est. completion 2027-08 1 siteOther conditions: Obesity & Overweight, Emotional Eating Behaviour, Mindful Eating InterventionView official trial listing → -
Not yet recruiting NCT NCT07653477
Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Metformin ± Sulfonylurea/SGLT2 Inhibitor Therapy (UNIGUIDE-2)
Not yet reported The United Bio-Technology (Hengqin) Co., Ltd. 956 participants Est. completion 2028-02-29Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07668414
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
Not yet reported Novo Nordisk A/S 650 participants Est. completion 2028-10-10 43 sites Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Not yet recruiting NCT NCT07668765
GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid Obesity
Gazi University 100 participants Est. completion 2027-05 1 siteOther conditions: Morbid Obesity, Anorectal Diseases, Drug-Related Side Effects and Adverse Reactions, Constipation, DiarrheaView official trial listing → -
Completed NCT NCT07677865
GLP-1 Receptor Agonists and Alzheimer's Disease: A Multi-National Target Trial Emulation
West China Hospital 213891 participants Est. completion 2026-06-24 1 siteType 2 diabetes Other conditions: Alzheimer Disease, Obesity & OverweightView official trial listing → -
Enrolling by invitation NCT NCT07677995
Free Fatty Acid Effects In Type 2 Diabetes
Not yet reported University of Ulster 60 participants Est. completion 2027-02 1 site Stand-aloneType 2 diabetesCardiovascular disease Other conditions: Omega-3 Fatty AcidsView official trial listing → -
Not yet recruiting NCT NCT07695454
Imaging in Semaglutide Study
The Cleveland Clinic 10 participants Est. completion 2027-06-01 1 siteType 2 diabetes Other conditions: BMI Greater Than 30View official trial listing → -
Not yet recruiting NCT NCT07711548
Can Two Dietary Interventions Maintain Weight Loss for 12 Months After GLP-1 Therapy in Adults With Overweight/Obesity?
Not yet reported Knut Mai 292 participants Est. completion 2030-04Other conditions: Obesity & Overweight, Weight Loss MaintenanceView official trial listing → -
Not yet recruiting NCT NCT07713992
Efficacy and Safety of Mazdutide in Patients With Type 2 Diabetes Mellitus and Moderate to Severe Nonalcoholic Fatty Liver Disease Previously Treated With Semaglutide
Not yet reported Tianjin Medical University 72 participants Est. completion 2028-02-01Type 2 diabetesMASLDView official trial listing → -
Not yet recruiting NCT NCT07720466
Salivary Function and Dental Changes During GLP-1 Therapy
Bilecik Seyh Edebali Universitesi 40 participants Est. completion 2027-03-17 1 siteOther conditions: Obesity, Dental Erosion, Saliva Collection, Saliva AlteredView official trial listing → -
Not yet recruiting NCT NCT07727473
Preoperative Semaglutide Prior to Radical Prostatectomy
Not yet reported Banner Health 20 participants Est. completion 2029-05 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Not yet recruiting NCT NCT07728812
Pragmatic Trial to Study the Cost-Effectiveness of MyPhenome-RX Test to Guide Anti-Obesity Pharmacotherapy
Not yet reported Phenomix Sciences 424 participants Est. completion 2029-01-01 Stand-aloneOther conditions: Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07731256
Semaglutide for Low Back Pain
Not yet reported Washington University School of Medicine 250 participants Est. completion 2031-09-01 2 sitesOther conditions: Lower Back Pain, Obesity (BMI>30), Chronic Lower Back Pain, glp1 AgonistView official trial listing → -
Not yet recruiting NCT NCT07737522
Myocardial Metabolic Flux in Pulmonary Arterial Hypertension
Not yet reported Imperial College London 32 participants Est. completion 2029-04-01Other conditions: Pulmonary Arterial HypertensionView official trial listing → -
Not yet recruiting NCT NCT07754045
Evaluating the Efficacy and Safety of LUM-201 Plus Semaglutide Versus Semaglutide Plus Placebo in Older Obese Adults
Not yet reported Lumos Pharma 202 participants Est. completion 2028-02-15 Stand-aloneOther conditions: Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07755085
GLP-1s in Hip and Knee Arthroplasty
Not yet reported Nova Scotia Health Authority 100 participants Est. completion 2028-12 1 siteOther conditions: Arthritis, Obesity & Overweight, GLP - 1View official trial listing → -
Not yet recruiting NCT NCT07760532
Comparing Facial Aging Between Identical Twins With 3D Imaging
Ponsky Facial Aesthetics And Plastic Surgery, Llc 200 participants Est. completion 2026-09 1 siteOther conditions: Facial Skin Aging, Facial Volume Loss, Wrinkle AppearanceView official trial listing → -
Not yet recruiting NCT NCT07760948
HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide
Not yet reported Vanderbilt University Medical Center 90 participants Est. completion 2030-11 1 site Stand-aloneType 2 diabetes Other conditions: Sarcopenia, Obesity, Muscle Loss, Older AdultsView official trial listing → -
Not yet recruiting NCT NCT07769047
Semaglutide and Structured Lifestyle Support to Improve Heart and Blood Vessel Health in Postmenopausal Obese Breast Cancer Survivors Taking Aromatase Inhibitors
Not yet reported Mayo Clinic 50 participants Est. completion 2035-07-30 1 siteOther conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8View official trial listing → -
Not yet recruiting NCT NCT07770152
Semaglutide in Youth With Autism Spectrum Disorder
Not yet reported Children's Hospital Medical Center, Cincinnati 42 participants Est. completion 2029-09-01 1 site Stand-aloneOther conditions: Autism Spectrum Disorder, ObesityView official trial listing → -
Not yet recruiting NCT NCT07770282
Efficacy and Safety of Semaglutide Versus Placebo on Cardiometabolic Profile in Patients With Schizophrenia With Metabolic Syndrome
Not yet reported All India Institute of Medical Sciences, Bhubaneswar 600 participants Est. completion 2030-12-30 Stand-aloneMetabolic syndrome Other conditions: Schizophrenia Disorder, Antipsychotic-induced Weight Gain, Cardiovascular Risk, Insulin ResistanceView official trial listing → -
Not yet recruiting NCT NCT07772960
Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes
Not yet reported Yale University 90 participants Est. completion 2031-10-31 1 siteAlcohol use disorder Other conditions: Obesity (BMI Equal to or >30)View official trial listing → -
Not yet recruiting NCT NCT07781371
A Retrospective Real-World Cohort Study
Novo Nordisk A/S 100000 participants Est. completion 2026-11-02 1 siteType 2 diabetesPrediabetesCardiovascular diseaseMASLDChronic kidney disease Other conditions: Obesity, DyslipidemiaView official trial listing → -
Not yet recruiting NCT NCT07783854
A Randomized Controlled Study of Dose-tapering Regimen of Semaglutide for Weight-Loss Maintenance in Adults With Overweight or Obesity
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 72 participants Est. completion 2029-06-30 Stand-aloneOther conditions: Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07787936
GLP-1/GIP Receptor Agonists in Obesity-Related HFpEF: The GLIDE-HF Registry
Miedziowe Centrum Zdrowia SA 150 participants Est. completion 2033-01-01 1 siteHeart failure Other conditions: Obesity, Pulmonary Hypertension, Iron DeficiencyView official trial listing → -
Not yet recruiting NCT NCT07797036
Postpartum Semaglutide to Reduce Cardiometabolic Risk After Gestational Diabetes
Not yet reported, Not yet reported University of Massachusetts, Worcester 226 participants Est. completion 2030-12-31 1 site Stand-aloneMetabolic syndrome Other conditions: Gestational Diabetes Mellitus (GDM)View official trial listing → -
Not yet recruiting NCT NCT07812597
A Study Evaluating Safety and Tolerability of Switching From Semaglutide to Zovaglutide in Adults With Obesity (HORIZON-SWITCH-SZ)
Not yet reported Beijing QL Biopharmaceutical Co.,Ltd 210 participants Est. completion 2028-03-24 16 sitesOther conditions: ObesityView official trial listing →
Efficacy history
Placebo-adjusted weight loss · 68 weeks
Adults with obesity or overweight, without type 2 diabetes
Trial: STEP 1 (Phase 3)
Source →Results from different trials are not directly comparable — populations, timepoints, and measurement methods differ between studies.
Safety
Gastrointestinal events were the most common adverse events and the main reason for treatment discontinuation.
Source →Sources
- FDA approval — Wegovy
- STEP 1 (NEJM)
- ClinicalTrials.gov — NCT07361874
- ClinicalTrials.gov — NCT07588984
- ClinicalTrials.gov — NCT04862923
- ClinicalTrials.gov — NCT07275697
- ClinicalTrials.gov — NCT07391267
- ClinicalTrials.gov — NCT05670379
- ClinicalTrials.gov — NCT04892199
Also known as: Semaglutide, Wegovy, Ozempic, Rybelsus, Semaglutide (administered by PDS290 pen-injector), Semaglutide (Rybelsus®), Semaglutide (1 Mg Dose), Intervention 2: Semaglutide, Microdose semaglutide, Oral semaglutide, Semaglutide 2.4 mg, Semaglutide Oral Tablet, Semaglutide, 1.0 mg/mL, Semaglutide, 1.34 mg/mL
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