About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Zoledronic Acid /Bag Infusion
- Company
- Chrissy Kistler
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 28 recruiting
Efficacy results: Not yet reported
28 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 24, 2026
Find a Clinical Trial Near Me
See recruiting studies for Zoledronic Acid /Bag Infusion and check eligibility with the study team.
Trial details
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Recruiting NCT NCT02508038
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
Not yet reported University of Wisconsin, Madison 22 participants Est. completion 2027-12 1 siteObstructive sleep apnea Other conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Myelodysplastic Syndrome, Myeloproliferative Syndrome, Ewing Sarcoma, Primitive Neuroectodermal Tumor, NeuroblastomaView official trial listing → -
Recruiting NCT NCT03295981
Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone
Not yet reported St. Louis University 120 participants Est. completion 2028-01 16 sitesOther conditions: Giant Cell Tumor of BoneView official trial listing → -
Recruiting NCT NCT03958565
Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations.
University of Colorado, Denver 100 participants Est. completion 2028-04-28 2 sitesOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Recruiting NCT NCT04608630
Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults
Not yet reported Australian and New Zealand Intensive Care Research Centre 450 participants Est. completion 2027-02-28 22 sitesOther conditions: Critical Illness, OsteoporosisView official trial listing → -
Recruiting NCT NCT04725422
CHronic Nonbacterial Osteomyelitis International Registry
Seattle Children's Hospital 2000 participants Est. completion 2050-08 1 siteOther conditions: Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal OsteomyelitisView official trial listing → -
Recruiting NCT NCT05400603
Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma
Not yet reported Emory University 24 participants Est. completion 2026-12 1 siteObstructive sleep apnea Other conditions: Neuroblastoma, Refractory Neuroblastoma, Relapsed NeuroblastomaView official trial listing → -
Recruiting NCT NCT05493267
A Exploratory Study of Vγ2Vδ2 T Lymphocyte-based Immunotherapy for MDR-TB
Not yet reported Shanghai Pulmonary Hospital, Shanghai, China 30 participants Est. completion 2027-08-03 2 sitesOther conditions: MDR-TB, ImmunotherapyView official trial listing → -
Recruiting NCT NCT05595603
Zoledronic Acid-loaded Bone Cement as a Local Adjuvant Therapy for Giant Cell Bone Tumor After Intralesional Curettage
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 153 participants Est. completion 2026-12-01 1 siteOther conditions: Giant Cell Tumor of BoneView official trial listing → -
Recruiting NCT NCT05677152
Influence of an Anti-osteoporotic Drug on Healing After Surgical Repair of Chronic Rotator Cuff Lesions of the Shoulder
Not yet reported AUVA Traumazentrum Vienna Site UKH Meidling 80 participants Est. completion 2030-12 1 siteOther conditions: Orthopedics, TraumatologyView official trial listing → -
Recruiting NCT NCT05904353
A Study to Improve the Collaboration Between Primary and Secondary Health Care on the Treatment of Osteoporosis After a Hip Fracture.
Not yet reported University Hospital, Akershus 200 participants Est. completion 2026-12 1 siteOther conditions: Hip Fractures, Osteoporosis, Zoledronic Acid, Ambulant Nurse, Case ManagerView official trial listing → -
Recruiting NCT NCT05906056
Continuous Passive Motion Versus Heterotopic Ossification
Not yet reported University of Ioannina 20 participants Est. completion 2027-03-25 1 siteCardiovascular disease Other conditions: Traumatic Brain Injury, Spinal Cord InjuriesView official trial listing → -
Recruiting NCT NCT06059222
The Optimised Use of Romozosumab Study
Not yet reported University of Aarhus 270 participants Est. completion 2032-08-31 1 siteOther conditions: OsteoporosisView official trial listing → -
Recruiting NCT NCT06118905
Preserving Geriatric Muscle With an Osteoporosis Medication
Not yet reported Chrissy Kistler 155 participants Est. completion 2029-03-31 1 siteOther conditions: OsteoporosisView official trial listing → -
Recruiting NCT NCT06164795
Sequential Therapies After Osteoanabolic Treatment
424 General Military Hospital 150 participants Est. completion 2027-12 8 sitesOther conditions: Osteoporosis, PostmenopausalView official trial listing → -
Recruiting NCT NCT06374459
Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis
Not yet reported, Not yet reported Washington University School of Medicine 152 participants Est. completion 2032-05-31 3 sitesOther conditions: Hormone Receptor Positive HER-2 Negative Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT06513624
ETC-159 In Combination With Pembrolizumab In Advanced MSS/pMMR Ovarian Cancers
Not yet reported National University Hospital, Singapore 16 participants Est. completion 2027-06-30 2 sitesOther conditions: With MSS/pMMR Advanced, Platinum-resistant Ovarian CancerView official trial listing → -
Recruiting NCT NCT06533865
Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea
Not yet reported Massachusetts General Hospital 114 participants Est. completion 2029-04 2 sitesOther conditions: FHA (Functional Hypothalamic Amenorrhea)View official trial listing → -
Recruiting NCT NCT06625190
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors
Not yet reported, Not yet reported University of Florida 27 participants Est. completion 2030-02 1 siteObstructive sleep apnea Other conditions: Neuroblastoma, Synovial Sarcoma, Peripheral Nerve Sheath Tumors, Clear Cell Sarcoma, Alveolar Soft Part Sarcoma, Desmoplastic Small Round Cell Tumor, Chordoma, Rhabdoid Tumor, Epithelioid Sarcoma, Myoepithelial Tumor, Ewing Sarcoma, Wilms TumorView official trial listing → -
Recruiting NCT NCT06643780
RANK-ligand Inhibition to Combat Sarcopenia With Underlying Osteoporosis
Not yet reported Prince of Wales Hospital, Shatin, Hong Kong 120 participants Est. completion 2027-10 1 siteOther conditions: Sarcopenia in ElderlyView official trial listing → -
Recruiting NCT NCT06759064
Intraperitoneal Immune Checkpoint Inhibitors and Zoledronic Acids for Gastric Cancer Malignant Ascites
Not yet reported, Not yet reported Qilu Hospital of Shandong University 24 participants Est. completion 2026-09-01 1 siteOther conditions: Cancer of Stomach, Adenocarcinoma, Ascites, MalignantView official trial listing → -
Recruiting NCT NCT06762730
Zoledronic Acid for the Prevention of TDF-sparing ART-induced Bone Mass Density Loss in Treatment-naive HIV Positive Individuals
Not yet reported Hadassah Medical Organization 110 participants Est. completion 2032-12-01 3 sitesOther conditions: HIV Infected Individuals, OsteopeniaView official trial listing → -
Recruiting NCT NCT06767150
StrAtegies For Zoledronic Acid Post-dEnosumab Discontinuation in Postmenopausal oSTeoporosis
Not yet reported University Hospital, Toulouse 200 participants Est. completion 2030-10 17 sitesOther conditions: Postmenopausal OsteoporosisView official trial listing → -
Recruiting NCT NCT06859580
Bisphosphonate Prior to Parathyroidectomy in Primary Hyperparathyroidism
Not yet reported University of Aarhus 140 participants Est. completion 2028-02-01 1 siteOther conditions: Primary HyperparathyroidismView official trial listing → -
Recruiting NCT NCT07043608
Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases
Not yet reported Kelly Fitzgerald, MD 20 participants Est. completion 2030-04-30 1 siteOther conditions: Clear Cell Renal Cell Cancer (ccRCC), Clear Cell Renal Carcinoma, Clear Cell Renal Cell Carcinoma Metastatic, Clear Cell Renal Cancer, Bone Metastases of a Malignant Tumor, Clear Cell Renal Cell Carcinoma, Bone, Metastatic Cancer, Metastatic Cancer, Metastatic Renal Cell Carcinoma, Metastases to BoneView official trial listing → -
Recruiting NCT NCT07281586
Step-down Therapy After Long-term Osteoporosis Treatment
Not yet reported National Taiwan University Hospital 44 participants Est. completion 2028-12-31 1 siteOther conditions: OsteoporosisView official trial listing → -
Recruiting NCT NCT07375290
Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors
Not yet reported Children's Hospital Medical Center, Cincinnati 20 participants Est. completion 2028-11 1 siteOther conditions: Hematopoietic Stem Cell TransplantationView official trial listing → -
Recruiting NCT NCT07406685
The Comparison of Ibandronate and Zoledronic Acid After Denosumab Discontinuation
Not yet reported National Taiwan University Hospital 52 participants Est. completion 2030-10-31 1 siteOther conditions: Postmenopausal Osteoporosis, Postmenopausal Osteopenia, Primary Osteoporosis, OsteoporosisView official trial listing → -
Recruiting NCT NCT07471516
Zoledronic Acid Treatment in Patients With Congenital Dyserythropoietic Anemia
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 2 participants Est. completion 2027-08-12 1 siteOther conditions: Congenital Dyserythropoietic Anemia (CDA)View official trial listing → -
Completed NCT NCT00003884
Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone
Not yet reported Novartis 600 participants Est. completion 2001-01 55 sitesOther conditions: Hypercalcemia of Malignancy, Lung Cancer, Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00004928
Calcitriol and Zoledronate in Treating Patients With Progressive Prostate Cancer
Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2004-10 1 siteOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00005073
Zoledronate Plus Standard Therapy Compared With Placebo Plus Standard Therapy to Prevent Bone Metastases in Patients With Recurrent Prostate Cancer That Has No Symptoms
Not yet reported Novartis Pharmaceuticals 544 participants Est. completion 2003-03 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00022087
Zoledronate, Calcium, and Vitamin D in Preventing Bone Loss in Women Receiving Adjuvant Chemotherapy for Breast Cancer
Not yet reported Alliance for Clinical Trials in Oncology 439 participants Est. completion 2009-02 107 sitesOther conditions: Breast Cancer, OsteoporosisView official trial listing → -
Completed NCT NCT00029224
Treatment With Zoledronic Acid in Patients With Breast Cancer, Multiple Myeloma, and Prostate Cancer With Cancer Related Bone Lesions
Not yet reported Novartis 500 participants Est. completion 2002-11 7 sitesOther conditions: Breast Cancer, Multiple Myeloma, Prostate CancerView official trial listing → -
Completed NCT NCT00033332
Dexamethasone With or Without Thalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma
Not yet reported National Cancer Institute (NCI) Est. completion 2006-06 78 sitesOther conditions: Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00035997
Open-label Trial on the Effect of I.V. Zoledronic Acid 4 mg on Bone Density in Hormone Sensitive Prostate Cancer Patients With Bone Metastasis
Not yet reported Novartis Pharmaceuticals 261 participants Est. completion 2004-01 56 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00039104
Zoledronate and BMS-275291 in Treating Patients With Prostate Cancer
Not yet reported National Cancer Institute (NCI) 50 participants 1 siteOther conditions: Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage IV Prostate CancerView official trial listing → -
Completed NCT NCT00046254
Evaluating the Ability of Zoledronic Acid to Reduce the Rate of Subsequent Osteoporotic Fractures After a Hip Fracture
Not yet reported Novartis Pharmaceuticals 2127 participants Est. completion 2007-02 28 sitesOther conditions: Osteoporosis, Hip FractureView official trial listing → -
Completed NCT NCT00049452
Zoledronate in Preventing Bone Loss in Premenopausal Women Receiving Chemotherapy After Surgery For Early Stage Breast Cancer
Not yet reported Herbert Irving Comprehensive Cancer Center 120 participants Est. completion 2008-08 3 sitesOther conditions: Breast Cancer, OsteoporosisView official trial listing → -
Completed NCT NCT00049829
HORIZON-PFT: Pivotal Fracture Trial
Not yet reported Novartis Pharmaceuticals 7700 participants 60 sitesOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00050011
Zoledronic Acid - Letrozole Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women With Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy
Not yet reported Novartis Pharmaceuticals 602 participants Est. completion 2009-01 44 sitesOther conditions: Breast Neoplasms, OsteoporosisView official trial listing → -
Completed NCT NCT00051636
Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period
Not yet reported Novartis Pharmaceuticals 172 participants Est. completion 2011-04 34 sitesOther conditions: Paget's Disease of BoneView official trial listing → -
Completed NCT NCT00051779
An Investigational Drug (CAL) Versus Zoledronic Acid (Zometa®) in Patients With Breast Cancer
Not yet reported Chugai Pharma USA 38 sitesOther conditions: Breast Neoplasms, Breast Cancer, MetastasisView official trial listing → -
Terminated NCT NCT00058188
Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen Deprivation
Not yet reported Northwestern University 53 participants Est. completion 2008-11 3 sitesOther conditions: Osteoporosis, Prostate CancerView official trial listing → -
Completed NCT NCT00060138
Monoclonal Antibody Compared With Zoledronate in Treating Women With Breast Cancer and Bone Metastases
Not yet reported, Not yet reported Chugai Pharmaceutical 1 siteOther conditions: Breast Cancer, Hypercalcemia of Malignancy, Metastatic Cancer, PainView official trial listing → -
Completed NCT NCT00063479
Bisphosphonate Treatment of Osteogenesis Imperfecta
Not yet reported Novartis Pharmaceuticals 158 participants Est. completion 2007-05 10 sitesOther conditions: Osteogenesis ImperfectaView official trial listing → -
Completed NCT NCT00063609
The Effect of Zoledronic Acid on Bone Loss in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy
Not yet reported Novartis Pharmaceuticals 200 participants Est. completion 2005-04 44 sitesOther conditions: Prostate CancerView official trial listing → -
Status unknown NCT NCT00072020
Chemotherapy and/or Hormone Therapy With or Without Zoledronate in Treating Women With Stage II or Stage III Breast Cancer
Not yet reported University of SheffieldOther conditions: Breast Cancer, Metastatic CancerView official trial listing → -
Completed NCT NCT00072930
MEDI-522 in the Treatment of Patients With Metastatic Androgen-Independent Prostate Cancer
Not yet reported MedImmune LLC 150 participants Est. completion 2007-06 57 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00079001
Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases
Not yet reported Alliance for Clinical Trials in Oncology 645 participants Est. completion 2014-10 241 sitesOther conditions: Metastatic Cancer, Prostate CancerView official trial listing → -
Completed NCT NCT00081159
Hormone Ablation Therapy, Doxorubicin, and Zoledronate With or Without Strontium 89 in Treating Patients With Androgen-Dependent Prostate Cancer and Bone Metastases
Not yet reported M.D. Anderson Cancer Center 80 participants Est. completion 2014-09 4 sitesOther conditions: Metastatic Cancer, Prostate CancerView official trial listing → -
Completed NCT NCT00083382
Combination Bisphosphonate and Anti-Angiogenesis Therapy With Pamidronate and Thalidomide
Not yet reported University of Arkansas 83 participants Est. completion 2014-05 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00086268
Non-small Cell Lung Cancer Study US75 (Z-PACT)
Not yet reported Novartis Pharmaceuticals 250 participants Est. completion 2007-10 80 sitesOther conditions: Non Small Cell Lung CarcinomaView official trial listing → -
Completed NCT NCT00087659
A Prostate Cancer Study in Men Undergoing Androgen Deprivation Therapy
Not yet reported Novartis Pharmaceuticals Est. completion 2007-05 16 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00091832
Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer
Not yet reported Amgen 255 participants Est. completion 2006-10Other conditions: Breast Cancer, Metastases, Bone Metastases in Subjects With Advanced Breast CancerView official trial listing → -
Completed NCT NCT00097812
Switching Osteoporosis Patients Currently on Oral Bisphosphonate to Zoledronic Acid
Not yet reported Novartis Pharmaceuticals 220 participants Est. completion 2005-12 13 sitesOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00097825
Efficacy and Safety of Zoledronic Acid for the Treatment of Osteoporosis in Men
Not yet reported Novartis Pharmaceuticals 288 participants Est. completion 2007-08 26 sitesOther conditions: OsteoporosisView official trial listing → -
Terminated NCT NCT00099177
A Study to Assess the Efficacy of Intravenous/Oral Bondronat (Ibandronate) in Patients With Metastatic Bone Disease Experiencing Moderate to Severe Pain
Not yet reported Hoffmann-La Roche 96 participants Est. completion 2007-12 41 sitesOther conditions: Pain, Bone Neoplasm, Neoplasm MetastasisView official trial listing → -
Terminated NCT NCT00099203
A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease
Not yet reported Hoffmann-La Roche 163 participants Est. completion 2007-12 72 sitesOther conditions: Pain, Bone Neoplasm, Neoplasm MetastasisView official trial listing → -
Completed NCT NCT00099541
Non-small Cell Lung Cancer Registry
Not yet reported Novartis Pharmaceuticals 300 participants Est. completion 2007-11 101 sitesOther conditions: Non-Small-Cell Lung Cancer, Pleural Effusion, MalignantView official trial listing → -
Completed NCT NCT00100555
A Study of the Clinical Safety, Tolerability, and Efficacy of Zoledronic Acid Compared to an Oral Bisphosphonate
Not yet reported Novartis Pharmaceuticals 120 participants Est. completion 2005-06 18 sitesOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00100620
Efficacy and Safety of Zoledronic Acid in the Prevention and Treatment of Corticosteroid Induced Osteoporosis
Not yet reported Novartis Pharmaceuticals 802 participants Est. completion 2007-04 6 sitesOther conditions: OsteoporosisView official trial listing → -
Status unknown NCT NCT00102908
Bisphosphonate Therapy for HIV-Infected Adults With Decreased Bone Mineral Density
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 30 participants Est. completion 2009-12 1 siteOther conditions: HIV Infections, Osteopenia, OsteoporosisView official trial listing → -
Completed NCT NCT00103740
Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period
Not yet reported Novartis Pharmaceuticals 185 participants Est. completion 2011-04 41 sitesOther conditions: Paget's Disease of BoneView official trial listing → -
Completed NCT NCT00104104
A Multiple Myeloma Trial in Patients With Bone Metastases
Not yet reported Novartis Pharmaceuticals 179 participants Est. completion 2007-10 68 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00104650
Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates
Not yet reported Amgen 111 participants Est. completion 2010-03Other conditions: Bone Metastases in Men With Hormone-Refractory Prostate Cancer, Bone Metastases in Subjects With Advanced Breast Cancer, Bone Metastases in Subjects With Advanced Cancer or Multiple MyelomaView official trial listing → -
Completed NCT NCT00107263
Zoledronate in Preventing Bone Loss in Postmenopausal Women Who Are Receiving Letrozole for Stage I, Stage II, or Stage IIIA Breast Cancer
Not yet reported Alliance for Clinical Trials in Oncology 558 participants Est. completion 2012-08Other conditions: Breast Cancer, OsteoporosisView official trial listing → -
Completed NCT NCT00114270
Letrozole With or Without Zoledronate in Treating Healthy Postmenopausal Women With High Breast Density
Not yet reported University of Virginia Est. completion 2007-06 1 siteOther conditions: Breast Cancer, OsteoporosisView official trial listing → -
Completed NCT NCT00114556
The Effect of Zoledronic Acid on Bone Density in Liver Transplant Patients
Not yet reported Royal Prince Alfred Hospital, Sydney, Australia 100 participants Est. completion 2004-08 1 siteOther conditions: Osteoporosis, Liver Transplantation, FracturesView official trial listing → -
Completed NCT NCT00120133
Atorvastatin (Lipitor) to Prevent Bone Pain
Not yet reported Children's Mercy Hospital Kansas City 12 participants Est. completion 2007-12 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00126386
Zometa for the Management of Tumor-induced Hypercalcemia and Malignant Bone Pain in the Community
Not yet reported Alberta Health services 11 participants Est. completion 2006-09 1 siteOther conditions: Cancer, Hypercalcemia, PainView official trial listing → -
Completed NCT NCT00127205
S0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer.
Not yet reported SWOG Cancer Research Network 6097 participants Est. completion 2021-03-29Other conditions: Breast CancerView official trial listing → -
Terminated NCT NCT00130494
Zoledronic Acid Administration to Metastatic Breast Cancer Patients With Non-symptomatic Bone Lesions
Not yet reported Spanish Breast Cancer Research Group 97 participants Est. completion 2007-10-22 1 siteOther conditions: Breast Cancer, Neoplasm MetastasisView official trial listing → -
Completed NCT NCT00131118
Zoledronic Acid in Children (1 -17 Years) With Severe Osteogenesis Imperfecta
Not yet reported Novartis Pharmaceuticals 127 participants Est. completion 2007-05 10 sitesOther conditions: Osteogenesis ImperfectaView official trial listing → -
Completed NCT NCT00132808
Zoledronic Acid in the Prevention of Bone Loss in Postmenopausal Women With Osteopenia, 45 Years of Age and Older
Not yet reported Novartis Pharmaceuticals 581 participants Est. completion 2008-02 1 siteOther conditions: OsteopeniaView official trial listing → -
Completed NCT NCT00145275
To Assess the Efficacy of Over-the-counter Analgesics in the Prevention/Treatment of Transient Post-dose Symptoms Following Zoledronate Infusion in Post-menopausal Women
Not yet reported Novartis 455 participants Est. completion 2005-10 10 sitesOther conditions: OsteopeniaView official trial listing → -
Completed NCT NCT00145327
Double-blind Extension of HORIZON Pivotal Fracture Trial (Zoledronic Acid in the Treatment of Postmenopausal Osteoporosis)
Not yet reported Novartis 2456 participants Est. completion 2009-11 31 sitesOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00151073
Estramustine, Docetaxel and Zoledronate Treatment in Hormone-Refractory Adenocarcinoma of the Prostate
Not yet reported University of Michigan Rogel Cancer Center 28 participants Est. completion 2007-09 1 siteOther conditions: Hormone-Refractory Prostate CancerView official trial listing → -
Completed NCT NCT00164008
Comparison of Pamidronate With Zoledronic Acid for Transplant Related Bone Loss Prevention
Not yet reported Bayside Health 56 participants Est. completion 2005-12Other conditions: Osteopenia, Complications of Heart-lung Transplant, Other Complications of Lung TransplantView official trial listing → -
Completed NCT NCT00171314
The Use of Zoledronic Acid to Prevent Cancer-treatment Bone Loss in Post-menopausal Women Receiving Adjuvant Letrozole for Breast Cancer
Not yet reported Novartis Pharmaceuticals 527 participants 49 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00171340
Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer.
Not yet reported Novartis Pharmaceuticals 1065 participants Est. completion 2010-02 106 sitesOther conditions: Bone Loss, Breast CancerView official trial listing → -
Completed NCT NCT00171639
The Use of Zoledronic Acid in Men on Androgen Deprivation Therapy for Prostate Cancer With Preexisting Osteoporosis
Not yet reported Novartis Pharmaceuticals 28 participants Est. completion 2007-03 7 sitesOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00171925
Therapy With Zoledronic Acid in Patients With Multiple Myeloma Stage I
Not yet reported Novartis Pharmaceuticals 143 participants Est. completion 2008-11 1 siteOther conditions: Multiple Myeloma Stage IView official trial listing → -
Completed NCT NCT00171964
Efficacy and Tolerability of Zoledronic Acid With Radiotherapy in Pts With Advanced Osteolytic Bone Lesions
Not yet reported Novartis Pharmaceuticals 75 participants Est. completion 2008-12 1 siteOther conditions: Pain, Neoplasm Metastasis, CancerView official trial listing → -
Completed NCT NCT00172003
Effect of Zoledronic Acid in Patients With Renal Cell Cancer and Bone Metastasis
Not yet reported Novartis Pharmaceuticals 50 participants Est. completion 2009-07 1 siteOther conditions: Renal Cell Cancer, Neoplasm MetastasisView official trial listing → -
Completed NCT NCT00172016
A Study to Evaluate the Efficacy and Tolerability of Zoledronic Acid in Patients With Metastatic Prostate Cancer Who Can be Treated With a Group of Medications Known as Bisphosphonates
Not yet reported Novartis Pharmaceuticals 43 participantsOther conditions: Prostate Cancer With at Least One Bone Lesion in Patients Receiving Hormonal Therapy and Treatment With Bisphosphonates is IndicatedView official trial listing → -
Completed NCT NCT00172029
Study Comparing Full-dose Radiotherapy Versus Reduced Dose in the Management of Bone Metastasis in Patients With Breast Cancer Receiving Zoledronic Acid
Not yet reported Novartis 116 participants 7 sitesOther conditions: Breast Cancer With Metastatic Bone DiseaseView official trial listing → -
Completed NCT NCT00172042
A Study to Evaluate the Safety and Efficacy of Zoledronic Acid in the Prevention or Delaying of Bone Metastasis in Patients With Stage IIIA and IIIB Non-small Cell Lung Cancer (NSCLC)
Not yet reported Novartis Pharmaceuticals 437 participants Est. completion 2010-06 69 sitesOther conditions: Non-Small-Cell Lung CancerView official trial listing → -
Completed NCT NCT00172055
Study to Assess Efficacy and Safety of Zoledronic Acid and the Value of Markers of Bone Resorption in the Prediction of Bone Metastases and Cancer Treatment-induced Bone Loss (CTIBL) in Patients With Prostate Cancer on Hormone Therapy
Not yet reported Novartis Pharmaceuticals 218 participants Est. completion 2009-07 19 sitesOther conditions: Cancer ProstateView official trial listing → -
Terminated NCT NCT00172068
Zoledronic Acid in the Treatment of Breast Cancer With Minimal Residual Disease in the Bone Marrow
Not yet reported Novartis Pharmaceuticals 96 participants 4 sitesOther conditions: Primary Breast CancerView official trial listing → -
Completed NCT NCT00181558
Atrasentan and Zometa for Men With Prostate Cancer Metastatic to Bone
Not yet reported Massachusetts General Hospital 44 participants Est. completion 2006-12 2 sitesOther conditions: Prostate Cancer, Adenocarcinoma of the ProstateView official trial listing → -
Completed NCT NCT00181584
Zoledronic Acid to Prevent Bone Loss During Androgen Deprivation Therapy for Prostate Cancer
Not yet reported Massachusetts General Hospital 60 participants 2 sitesOther conditions: Bone Loss, Prostate CancerView official trial listing → -
Completed NCT NCT00193856
RADAR Trial - Randomised Androgen Deprivation and Radiotherapy
Not yet reported Trans Tasman Radiation Oncology Group 1071 participants Est. completion 2017-08 24 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00202059
Effects of Zometa and Physical Activity on Bone Density in Women Receiving Chemotherapy for Breast Cancer
Not yet reported HealthPartners Institute 72 participants Est. completion 2007-09 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00206388
Zoledronic Acid (ZOMETA) With Cyclophosphamide With Neuroblastoma and Cortical Bone Involvement
Not yet reported Baylor College of Medicine 21 participants Est. completion 2013-05 8 sitesOther conditions: NEUROBLASTOMAView official trial listing → -
Terminated NCT NCT00210119
Imatinib Mesylate and Zoledronic Acid in Patients With Chronic Myeloid Leukaemia in Cytogenetic Response Without Molecular Response
Not yet reported Institut Bergonié 19 participants Est. completion 2009-03 7 sitesOther conditions: Myeloid Leukemia, ChronicView official trial listing → -
Completed NCT NCT00213980
Bone Mineral Density Effects of Zoledronate in Postmenopausal Women With Breast Cancer
Not yet reported University of Wisconsin, Madison 68 participants Est. completion 2008-04 1 siteOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT00215943
Phase III Randomized Trial of Thalidomide/Dexamethasone Versus Vincristine+Adriamycin+Dexamethasone (VAD)
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 90 participants Est. completion 2012-08 5 sitesOther conditions: Multiple MyelomaView official trial listing → -
Terminated NCT NCT00216151
Zoledronic Acid in the Management of Patients With Asymptomatic/Early Stage Multiple Myeloma
Not yet reported Hoosier Cancer Research Network 3 participants Est. completion 2007-03 8 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00219219
Zoledronic Acid in the Prevention of Skeletal-related Events in Hormone Refractory and Hormone-sensitive Prostate Cancer Patients With Bone Metastases
Not yet reported Novartis Est. completion 2006-10 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00219258
Efficacy and Safety of Zoledronic Acid in Patients With Bone Metastases of Any Solid Tumors or Multiple Myeloma
Not yet reported Novartis 240 participants 1 siteOther conditions: Treatment of Bone MetastasesView official trial listing → -
Completed NCT NCT00219271
Effect Of Zoledronic Acid On Circulating And Bone Marrow-Residing Prostate Cancer Cells In Patients With Clinically Localized Prostate Cancer
Not yet reported Novartis Pharmaceuticals 60 participants Est. completion 2009-09 1 siteOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00226954
Zoledronic Acid With Intermittent Hormonal Therapy in Patients With Prostate Cancer
Not yet reported Stanford University 23 participants Est. completion 2009-02 1 siteOther conditions: Urologic NeoplasmsView official trial listing → -
Completed NCT NCT00237146
Study to Evaluate Zoledronic Acid on Quality of Life and Skeletal-related Events as Adjuvant Treatment in Patients With Hormone-naïve Prostate Cancer and Bone Metastasis Who Have Undergone Orchiectomy
Not yet reported Novartis Pharmaceuticals 38 participants Est. completion 2008-03 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00237159
Effect of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastasis
Not yet reported Novartis Pharmaceuticals 284 participantsOther conditions: Prostate Cancer Patients With Bone MetastasisView official trial listing → -
Completed NCT NCT00241111
Assessment of the Efficacy, Tolerability and Pharmaco-economic Impact of Zoledronic Acid Treatment in Prostate Cancer With Bone Metastasis
Not yet reported Novartis Pharmaceuticals 148 participantsOther conditions: Prostate Cancer With Bone MetastasisView official trial listing → -
Completed NCT NCT00242203
Evaluation of Chemotherapy Prior to Surgery With or Without Zometa for Women With Locally Advanced Breast Cancer
Not yet reported Washington University School of Medicine 120 participants Est. completion 2011-05 1 siteOther conditions: Breast NeoplasmsView official trial listing → -
Withdrawn NCT NCT00242528
Open-label Study, to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Bone Lesions Secondary to Multiple Myeloma.
Not yet reported NovartisOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00242554
Open-label Phase IV Clinical Trial to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastases
Not yet reported Novartis Pharmaceuticals 150 participantsOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00242567
Study of Zoledronic Acid for Patients With Hormone-sensitive Bone Metastases From Prostate Cancer
Not yet reported Novartis Pharmaceuticals 522 participants Est. completion 2012-01 27 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00247650
Comparison Study of Letrozole Alone or Letrozole With Zoledronic Acid in Early Breast Cancer, Neoadjuvant Therapy
Not yet reported Novartis 190 participants 10 sitesOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT00258258
Paricalcitol and Zoledronate in Treating Patients With Relapsed or Refractory Multiple Myeloma or Other Plasma Cell Disorders
Not yet reported Roswell Park Cancer Institute 7 participants 1 siteOther conditions: Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Terminated NCT NCT00258765
Adjuvant Docetaxel-Zoledronic Acid in High-risk Early Prostate Cancer Following Prostatectomy.
Not yet reported Novartis Pharmaceuticals 1 participants 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00263484
Higher Frequency Zoledronic Acid in the Treatment of Multiple Myeloma
Not yet reported Gleneagles Hospital 56 participants Est. completion 2010-10 10 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00264082
Assessment of Tartrate-Resistant Acid Phosphatase (TRAP) as a Bone Resorption Marker in Stage IV Breast Cancer Patients With Bone Metastasis
University of Louisville 30 participants 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00264420
Safety and Efficacy Study of Concomitant Radiotherapy and Zoledronic Acid for Bone Metastases Palliation
Not yet reported The Cleveland Clinic 4 participants Est. completion 2007-03Other conditions: Bone Metastases, Breast Cancer, Lung Cancer, Prostate CancerView official trial listing → -
Terminated NCT NCT00265200
Using TRAP to Evaluate the Effect of Zometa on Bone Metastasis Due to Lung Cancer
Not yet reported University of Louisville 28 participants Est. completion 2010-12 1 siteOther conditions: Carcinoma, Non-Small Cell Lung, Carcinoma, Small Cell Lung, MetastasesView official trial listing → -
Active, not recruiting NCT NCT00268476
Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy
Not yet reported, Not yet reported Medical Research Council 11992 participants Est. completion 2030-12 120 sitesOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00278434
Zoledronate in Treating Patients With Cervical Intraepithelial Neoplasia 2/3 or 3
Not yet reported University of California, San Francisco 12 participants Est. completion 2008-07 1 siteOther conditions: Cervical Cancer, Precancerous ConditionView official trial listing → -
Completed NCT NCT00287261
A Trial of Zoledronic Acid in Patients With Myelofibrosis With Myeloid Metaplasia (MMM)
Not yet reported Universitaire Ziekenhuizen KU Leuven 17 participants Est. completion 2008-03 6 sitesOther conditions: Myelofibrosis, Myeloid MetaplasiaView official trial listing → -
Terminated NCT NCT00294437
ZOMETA® (Zoledronic Acid) for Prevention of Bone Metastases
Not yet reported Central European Cooperative Oncology Group 376 participants Est. completion 2007-11 57 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00295646
Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic Acid
Not yet reported Austrian Breast & Colorectal Cancer Study Group 1803 participants Est. completion 2018-06-26 72 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00295867
Zoledronate in Treating Bone Marrow Micrometastases in Women With Stage I, Stage II, or Stage III Breast Cancer
Not yet reported University of California, San Francisco 45 participants Est. completion 2013-12 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00297830
Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Organ Transplantation
Not yet reported, Not yet reported Columbia University 111 participants Est. completion 2014-01 1 siteOther conditions: Heart Transplantation, Liver Transplantation, Bone ResorptionView official trial listing → -
Completed NCT NCT00301873
Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma
Not yet reported Duke University 60 participants Est. completion 2012-09 1 siteOther conditions: Brain Tumors, Osteoporosis, Central Nervous System(CNS)MalignanciesView official trial listing → -
Withdrawn NCT NCT00301886
S0308 Zoledronate or Ibandronate in Preventing Bone Problems in Women With Stage IV Breast Cancer That Has Spread to the Bone
Not yet reported SWOG Cancer Research Network Est. completion 2006-05Other conditions: Breast Cancer, Hypercalcemia of Malignancy, Metastatic Cancer, PainView official trial listing → -
Status unknown NCT NCT00302484
Use of Bisphosphonates in the Treatment of Osteopathy After Liver Transplantation
Not yet reported Medical University of Vienna 96 participants 1 siteOther conditions: Osteoporosis, Liver TransplantationView official trial listing → -
Completed NCT NCT00305695
Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries
Not yet reported Gynecologic Oncology Group 160 participants 95 sitesOther conditions: Hereditary Breast and Ovarian Cancer Syndrome, Osteoporosis, Ovarian CarcinomaView official trial listing → -
Completed NCT NCT00320710
Continued Efficacy and Safety of Zoledronic Acid (q 4 Wks vs. q 12 Wks) in the 2nd Year of Treatment in Patients With Bone Metastases From Breast Cancer
Not yet reported Novartis Pharmaceuticals 416 participants Est. completion 2013-07 92 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00321464
A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.
Not yet reported Amgen 2049 participants Est. completion 2012-04-04Other conditions: Bone MetastasesView official trial listing → -
Completed NCT NCT00321620
Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer
Not yet reported Amgen 1904 participants Est. completion 2012-02-24Other conditions: Bone MetastasesView official trial listing → -
Completed NCT NCT00321932
Zoledronic Acid in Preventing Osteoporosis in Patients Undergoing Donor Stem Cell Transplant
Not yet reported University of Minnesota 61 participants Est. completion 2012-03 2 sitesOther conditions: Leukemia, Lymphoma, Myelodysplastic Syndromes, Osteoporosis, Ovarian CancerView official trial listing → -
Status unknown NCT NCT00326820
Ibandronate or Zoledronate in Treating Patients With Newly Diagnosed Bone Metastases From Breast Cancer
Not yet reported Wales Cancer Trials Unit 1404 participants Est. completion 2015-10 79 sitesOther conditions: Breast Cancer, Hypercalcemia of Malignancy, Metastatic CancerView official trial listing → -
Completed NCT NCT00329797
Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy
Not yet reported Radiation Therapy Oncology Group 109 participants Est. completion 2014-11 88 sitesOther conditions: Osteoporosis, Prostate CancerView official trial listing → -
Completed NCT NCT00330759
Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma.
Not yet reported Amgen 1779 participants Est. completion 2011-10-01Other conditions: Bone MetastasesView official trial listing → -
Completed NCT NCT00332709
Safety/Efficacy of Letrozole Monotherapy or in Combination With Zoledronic Acid as Extended Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer
Not yet reported Novartis 83 participants Est. completion 2010-08 23 sitesOther conditions: Osteoporosis, PostmenopausalView official trial listing → -
Terminated NCT NCT00333229
A Study of Zoledronic Acid in the Prevention of Cancer Therapy-induced Bone Loss
Not yet reported Novartis Pharmaceuticals 11 participants Est. completion 2013-12 1 siteOther conditions: Primary Hormone Receptor Negative Breast Cancer in Premenopausal WomenView official trial listing → -
Completed NCT NCT00334139
Effect of Zoledronic Acid on Bone Metabolism in Patients With Bone Metastasis and Prostate or Breast Cancer
Not yet reported Novartis Pharmaceuticals 411 participants Est. completion 2009-07 1 siteOther conditions: Prostate Cancer, Breast Cancer, Bone MetastasisView official trial listing → -
Completed NCT NCT00346242
Evaluation of Efficacy of Zoledronic Acid in Patients With Haemoglobin Syndromes (Thalassemia and Sicle Cell Anaemia) and Risk of Skeletal Events
Not yet reported Novartis Pharmaceuticals 60 participants 1 siteOther conditions: ThalassemiaView official trial listing → -
Completed NCT NCT00352846
Effect of Zoledronic Acid on Chemotherapy Induced Bone Loss
Not yet reported M.D. Anderson Cancer Center 135 participants Est. completion 2011-09 1 siteOther conditions: Non-Hodgkin's Lymphoma, LymphomaView official trial listing → -
Completed NCT NCT00361595
Intervenous (IV) Zoledronic Acid After Forteo in Postmenopausal Women
Not yet reported The Cleveland Clinic 35 participants Est. completion 2008-04 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00365105
Zoledronate, Vitamin D, and Calcium With or Without Strontium 89 or Samarium 153 in Preventing or Delaying Bone Problems in Patients With Bone Metastases From Prostate Cancer, Lung Cancer, or Breast Cancer
Not yet reported Radiation Therapy Oncology Group 261 participants Est. completion 2017-02-27 147 sitesOther conditions: Breast Cancer, Lung Cancer, Metastatic Cancer, Pain, Prostate CancerView official trial listing → -
Terminated NCT NCT00372710
Safety/Efficacy of Intravenous Zoledronic Acid When Added to Standard Therapies in Patients With Breast Cancer and Metastatic Bone Lesions
Not yet reported Novartis 30 participants 1 siteOther conditions: Breast Cancer With Bone MetastasisView official trial listing → -
Completed NCT NCT00375427
Safety and Efficacy of Zoledronic Acid in Patients With Breast Cancer With Metastatic Bone Lesions
Not yet reported Novartis Pharmaceuticals 430 participants 1 siteOther conditions: Breast Cancer With Bone MetastasisView official trial listing → -
Completed NCT NCT00375505
The Safety and Efficacy of Zoledronic Acid in the Prevention of Cancer Therapy Induced Bone Loss
Not yet reported Novartis Pharmaceuticals 70 participants Est. completion 2014-05 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00375648
Efficacy and Safety of Zoledronic Acid in the Treatment of Bone Metastases-related Pain in Patients With Prostate Cancer
Not yet reported Novartis Pharmaceuticals 61 participants 1 siteOther conditions: PainView official trial listing → -
Terminated NCT NCT00375752
Efficacy and Safety of Letrozole vs. Letrozole Plus Zoledronic Acid as Endocrine Therapy Before Surgery in Postmenopausal Patients With Breast Cancer
Not yet reported Novartis Pharmaceuticals 168 participants Est. completion 2010-12-16 27 sitesOther conditions: Breast NeoplasmsView official trial listing → -
Completed NCT NCT00376740
Effectiveness of Zoledronic Acid in the Prevention of Osteoporosis in Early Breast Cancer Patients Receiving Letrozole
Not yet reported Soroka University Medical Center 90 participants 2 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00391690
Evaluation of Bone Markers as Diagnostic Tools for Early Detection of Bone Metastases in Patients With High Risk Prostate Cancer
Not yet reported Novartis 99 participants 1 siteOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00391950
Maintaining Bone Strength in Men With Prostate Cancer
Not yet reported Novartis 300 participants 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00399802
A Study to Examine the Effects of an Experimental Drug on Women With Breast Cancer and Metastatic Bone Disease (MBD)(0822-016)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 43 participants Est. completion 2007-12-05Other conditions: Breast Cancer, Metastatic Bone DiseaseView official trial listing → -
Completed NCT NCT00404820
Safety/Efficacy of Zoledronic Acid and Alendronate on Bone Metabolism in Postmenopausal Women With Osteoporosis
Not yet reported Novartis 604 participants Est. completion 2008-12 1 siteOther conditions: OsteoporosisView official trial listing → -
Status unknown NCT NCT00412022
HOBOE: A Phase 3 Study of Adjuvant Triptorelin and Tamoxifen, Letrozole, or Letrozole and Zoledronic Acid in Premenopausal Patients With Breast Cancer.
Not yet reported National Cancer Institute, Naples 1294 participants Est. completion 2024-11 20 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00415779
ZANTE: Zometa and Taxotere in Hormone Refractory Prostate Cancer
Not yet reported National Cancer Institute, Naples 36 participants Est. completion 2009-07 2 sitesOther conditions: Metastatic Prostate CancerView official trial listing → -
Completed NCT NCT00424983
Study of Zoledronic Acid Administered Monthly Versus Every 3 Months in Multiple Myeloma and Breast Cancer Patients Who Were Treated With Zoledronic Acid the Prior Year
Not yet reported Novartis Pharmaceuticals 18 participants Est. completion 2009-11 7 sitesOther conditions: Multiple Myeloma, Breast CancerView official trial listing → -
Completed NCT NCT00431444
Effects of Zoledronic Acid and Raloxifene on Bone Turnover Markers in Postmenopausal Women With Low Bone Mineral Density
Not yet reported Novartis 110 participants Est. completion 2008-07 17 sitesOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00432458
Zoledronate With or Without Thalidomide in Treating Patients With Early Stage Multiple Myeloma
Not yet reported Mayo Clinic 68 participants Est. completion 2012-04 4 sitesOther conditions: Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00434317
Assessment of Pain and Quality of Life in Breast and Prostate Cancer Patients With Bone Metastases
Not yet reported Novartis 80 participants 4 sitesOther conditions: Neoplasm MetastasisView official trial listing → -
Completed NCT NCT00434447
Long Term Efficacy and Safety of Zoledronic Acid Treatment in Patients With Bone Metastases
Not yet reported Novartis Pharmaceuticals 73 participants 10 sitesOther conditions: Bone NeoplasmsView official trial listing → -
Completed NCT NCT00436917
Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer
Not yet reported Mayo Clinic 60 participants Est. completion 2016-05-09 2 sitesOther conditions: Breast Cancer, OsteoporosisView official trial listing → -
Completed NCT NCT00439244
Efficacy Study of Zoledronic Acid and Teriparatide Combination Therapy in Women With Osteoporosis
Not yet reported Novartis 412 participants Est. completion 2009-02 33 sitesOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00439647
Efficacy in Reducing Fractures and Safety of Zoledronic Acid in Men With Osteoporosis
Not yet reported Novartis Pharmaceuticals 1199 participants Est. completion 2010-10 128 sitesOther conditions: Male OsteoporosisView official trial listing → -
Terminated NCT NCT00458796
Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone
Not yet reported University of Leeds 1500 participants 30 sitesOther conditions: Breast Cancer, Hypercalcemia of Malignancy, Metastatic Cancer, Musculoskeletal Complications, PainView official trial listing → -
Active, not recruiting NCT NCT00470223
Combined Chemotherapy With or Without Zoledronic Acid for Patients With Osteosarcoma
Not yet reported UNICANCER 318 participants Est. completion 2026-12 37 sitesOther conditions: SarcomaView official trial listing → -
Withdrawn NCT NCT00477217
Zoledronic Acid Treatment of Spontaneous Osteonecrosis of the Knee
Not yet reported Novartis Est. completion 2009-05 1 siteOther conditions: OsteonecrosisView official trial listing → -
Completed NCT NCT00482378
Samarium Sm 153 Lexidronam Pentasodium Combined With Zoledronic Acid or Pamidronate in Treating Patients With Relapsed or Refractory Multiple Myeloma and Bone Pain
Not yet reported, Not yet reported Mayo Clinic 39 participants Est. completion 2008-12-02 1 siteOther conditions: Multiple Myeloma and Plasma Cell Neoplasm, PainView official trial listing → -
Completed NCT NCT00489424
Acetaminophen or Fluvastatin Compared to Placebo on the Transient Post-Dose Symptoms (PDS) Following an Intravenous (i.v.) Infusion of a Single Dose of Zoledronic Acid 5mg, in Post-menopausal Women With Low Bone Mass
Not yet reported Novartis Pharmaceuticals 793 participants Est. completion 2007-12 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00489905
Study on Evaluation of Zoledronic Acid to Prevent Bone Loss in Men Receiving Androgen Deprivation Therapy for Prostate Cancer
Not yet reported Hospital Authority, Hong Kong 24 participants Est. completion 2008-05 1 siteOther conditions: Prostatic Neoplasms, Bone DensityView official trial listing → -
Completed NCT NCT00490698
Zoledronate With Atorvastatin in Renal Cell Carcinoma
Not yet reported M.D. Anderson Cancer Center 11 participants Est. completion 2012-01 1 siteOther conditions: Kidney Cancer, Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00512993
Postoperative Use of Zoledronic Acid in Breast Cancer Patients After Neoadjuvant Chemotherapy
Not yet reported GBG Forschungs GmbH 654 participants Est. completion 2013-11 93 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00520052
Frequency of Zoledronic Acid to Prevent Further Bone Loss in Osteoporotic Patients Requiring Androgen Deprivation Therapy for Prostate Cancer
Not yet reported Wirral University Teaching Hospital NHS Trust 58 participants Est. completion 2005-08 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00524849
Zometa and Circulating Vascular Endothelial Growth Factor (VEGF) in Breast Cancer Patients With Bone Metastasis
Not yet reported, Not yet reported Fudan University 60 participants Est. completion 2010-01 1 siteOther conditions: Metastatic Breast Cancer, Bone MetastasesView official trial listing → -
Completed NCT NCT00525759
Investigating the Biological Effects of the Addition of Zoledronic Acid to Pre-operative Chemotherapy in Breast Cancer
Not yet reported Sheffield Teaching Hospitals NHS Foundation Trust 40 participants Est. completion 2010-01 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00554918
Docetaxel and Prednisolone With or Without Zoledronic Acid and/or Strontium Chloride Sr 89 in Treating Patients With Prostate Cancer Metastatic to Bone That Has Not Responded to Hormone Therapy
Not yet reported University Hospital Birmingham 300 participants Est. completion 2013-06 16 sitesOther conditions: Metastatic Cancer, Prostate CancerView official trial listing → -
Completed NCT NCT00556374
Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy
Not yet reported Amgen 3420 participants Est. completion 2022-07-26 46 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00558012
Zoledronic Acid for Osteoporosis in the Elderly
Not yet reported University of Pittsburgh 181 participants Est. completion 2014-02 1 siteOther conditions: Osteoporosis, Bone Loss, Fragility FracturesView official trial listing → -
Completed NCT NCT00558272
Study to Evaluate the Safety and Effects AZD0530 on Prostate and Breast Cancer Subjects With Metastatic Bone Disease
Not yet reported AstraZeneca 139 participants Est. completion 2012-08 28 sitesOther conditions: Breast Cancer, Prostate Cancer, Bone NeoplasmsView official trial listing → -
Terminated NCT NCT00559897
Zoledronic Acid and Positron Emission Tomography in Treating Patients With Advanced Non-Small Cell Lung Cancer
Not yet reported Barbara Ann Karmanos Cancer Institute 6 participants Est. completion 2011-04 1 siteOther conditions: Lung Cancer, Metastatic CancerView official trial listing → -
Completed NCT NCT00566618
Dasatinib in Combination With Zoledronic Acid for the Treatment of Breast Cancer With Bone Metastasis
Not yet reported, Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2020-11-17 3 sitesOther conditions: Breast Cancer, Bone MetastasesView official trial listing → -
Completed NCT NCT00577642
Bone Marker Assessment of Multiple Myeloma Patients Treated With Aminobisphosphonates
Not yet reported Massachusetts General Hospital 29 participants Est. completion 2012-12 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00580047
Effects of Zoledronic Acid Versus Alendronate on Bone Loss After Kidney and Kidney/Pancreas Transplants
Not yet reported University of Nebraska 59 participants Est. completion 2014-07-29 1 siteOther conditions: Renal InsufficiencyView official trial listing → -
Completed NCT NCT00582556
Zometa on Bone Mineral Density in Prostate Cancer Patients Undergoing Androgen Ablation Therapy
Not yet reported University of Wisconsin, Madison 44 participants Est. completion 2013-03 1 siteOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00582790
Study of IL2 in Combination With Zoledronic Acid in Patients With Kidney Cancer
Not yet reported University of Wisconsin, Madison 12 participants Est. completion 2008-09 1 siteOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00582920
Investigation of Changes in Bone Scan Imaging Before and After Intravenous Bisphosphonate Therapy for Osseous Metastases From Breast Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 10 participants Est. completion 2008-10 1 siteOther conditions: Osseous Lesions From Metastatic Breast CancerView official trial listing → -
Completed NCT NCT00588913
Adoptive Immunotherapy, Aldesleukin, and Zoledronate in Treating Patients With Stage IV Kidney Cancer and Lung Metastases
Not yet reported, Not yet reported Tokyo Women's Medical University 20 participants Est. completion 2009-08 2 sitesOther conditions: Kidney Cancer, Metastatic CancerView official trial listing → -
Completed NCT NCT00622505
Zoledronic Acid Treatment (Every 4 or 12 Weeks) to Prevent Skeletal Complications in Advanced Multiple Myeloma Participants
Not yet reported Novartis Pharmaceuticals 121 participants Est. completion 2012-04-03 42 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00636740
Multi-Center Phase II Study to Compare MER-101 20mg Tablets to Intravenous Zometa 4mg in Male Bisphosphonate-Naive, Hormone Refractory Prostate Cancer Patients
Not yet reported Merrion Pharmaceuticals, LLC 30 participants Est. completion 2009-02 13 sitesOther conditions: Hormone-Refractory Prostate CancerView official trial listing → -
Withdrawn NCT NCT00639392
Phase 1 Study of Zoledronic Acid in Sickle Cell Disease
Not yet reported, Not yet reported Virginia Commonwealth University Est. completion 2008-05 1 siteOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT00668200
Impact on Reducing the Incidence of Low Serum Calcium by Providing Educational Materials on the Need to Take Daily Supplemental Calcium and Vitamin D to Patients With Paget's Disease Treated With Reclast®
Not yet reported Novartis Pharmaceuticals 81 participants Est. completion 2012-11 9 sitesOther conditions: Paget's Disease of the Bone, HypocalcemiaView official trial listing → -
Completed NCT NCT00685646
Androgen Blockade Therapy With or Without Zoledronic Acid in Treating Patients With Prostate Cancer and Bone Metastases
Not yet reported Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan 227 participants Est. completion 2014-01 1 siteOther conditions: Metastatic Cancer, Prostate CancerView official trial listing → -
Status unknown NCT NCT00691236
Evaluation of Zoledronic Acid as a Single Agent or as an Adjuvant to Chemotherapy in High Grade Osteosarcoma
Not yet reported, Not yet reported Tata Memorial Hospital 60 participants Est. completion 2013-08 1 siteObstructive sleep apneaView official trial listing → -
Completed NCT NCT00697619
To Evaluate the Efficacy of ZOMETA® in Treatment of Bone Metastases in Patients With Stage IV Nasopharyngeal Cancer
Not yet reported Sun Yat-sen University 60 participants Est. completion 2009-09 1 siteOther conditions: Nasopharyngeal CancerView official trial listing → -
Completed NCT NCT00712985
Single Dosing of Zoledronic Acid in Cancer Therapy Induced Bone Loss (CTIBL)
Not yet reported Milton S. Hershey Medical Center 18 participants Est. completion 2011-03 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00718861
3 yr Efficacy & Safety Study of Zoledronic Acid in Post-menopausal Women With Osteoporosis Treated With Zol Acid for 6 Yrs
Not yet reported Novartis Pharmaceuticals 190 participants Est. completion 2013-04 57 sitesOther conditions: Post-menopausal OsteoporosisView official trial listing → -
Completed NCT NCT00731016
Treatment of the Hutchinson-Gilford Progeria Syndrome With a Combination of Pravastatin and Zoledronic Acid
Not yet reported Assistance Publique Hopitaux De Marseille 15 participants Est. completion 2013-07 1 siteOther conditions: Hutchinson-Gilford Progeria SyndromeView official trial listing → -
Completed NCT NCT00733538
Stage I Multiple Myeloma Treatment
Not yet reported Centre Hospitalier Universitaire de Nice 89 participants Est. completion 2012-11 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00740129
Re-treatment of Participants With Paget's Disease Using Zoledronic Acid
Not yet reported Novartis Pharmaceuticals 6 participants Est. completion 2011-03-14 11 sitesOther conditions: Paget's Disease of the BoneView official trial listing → -
Completed NCT NCT00741377
A Study to Assess BHQ880 in Combination With Zoledronic Acid in Relapsed or Refractory Myeloma Patients
Not yet reported Novartis Pharmaceuticals 28 participants Est. completion 2011-12 9 sitesOther conditions: Multiple Myeloma Bone DiseaseView official trial listing → -
Completed NCT NCT00742924
Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma
Not yet reported Children's Oncology Group 24 participants 88 sitesOther conditions: SarcomaView official trial listing → -
Completed NCT NCT00745485
Feasibility of Doctors' Rooms-based Infusion of Zoledronic Acid
Not yet reported Novartis Pharmaceuticals 186 participants 14 sitesOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00760370
Comparison of Zometa Retention and Effect in Multiple Myeloma and Breast Cancer
Not yet reported Vejle Hospital 60 participants Est. completion 2011-12 2 sitesOther conditions: Multiple Myeloma, Breast CancerView official trial listing → -
Completed NCT NCT00762346
Efficacy and Safety Study of ZOMETA® in Treatment of High-level NTX Non Small Cell Lung Cancer With Bone Metastasis
Not yet reported Sun Yat-sen University 156 participants Est. completion 2013-03 1 siteOther conditions: Non Small Cell Lung Cancer, Bone Metastases, High NTX LevelView official trial listing → -
Completed NCT NCT00765687
Screening Non Small Cell Lung Cancer With Bone Metastasis and Efficacy and Safety Research of Receiving Bisphosphonates
Not yet reported Sun Yat-sen University 432 participants Est. completion 2012-05 1 siteOther conditions: Non-small Cell Lung Cancer, Bone MetastasesView official trial listing → -
Completed NCT NCT00774020
Efficacy and Safety of Single Dose of 5 mg Zoledronic Acid in Chinese Patients With Paget's Disease of Bone (PDB)
Not yet reported Novartis Pharmaceuticals 9 participants Est. completion 2011-01-14 4 sitesOther conditions: Paget's Disease of BoneView official trial listing → -
Status unknown NCT NCT00781261
Osteonecrosis of the Hip and Bisphosphonate Treatment
Not yet reported University of Sydney 120 participants Est. completion 2013-12 5 sitesOther conditions: OsteonecrosisView official trial listing → -
Completed NCT NCT00795483
Efficacy And Security Of Annual And Biennial Zoledronic Acid For Osteoporosis Treatment In An HIV-Infected Patients' Cohort
Not yet reported Germans Trias i Pujol Hospital 33 participants Est. completion 2011-11 1 siteOther conditions: HIV InfectionsView official trial listing → -
Completed NCT NCT00798473
Zoledronate for Osteopenia in Pediatric Crohn's
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 13 participants Est. completion 2008-11 1 siteOther conditions: Crohn's Disease, Osteopenia, OsteoporosisView official trial listing → -
Completed NCT NCT00799266
An Efficacy and Safety Trial of Intravenous Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids
Not yet reported Novartis Pharmaceuticals 34 participants Est. completion 2018-03-05 12 sitesOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT00807963
Pharmacokinetic, Safety and Tolerability Study of SC Administered Bisphosphonate With rHuPH20 vs Bisphosphonate Alone
Not yet reported Halozyme Therapeutics 31 participants Est. completion 2009-09-21 1 siteOther conditions: Risk Factors for or a Diagnosis of OsteoporosisView official trial listing → -
Terminated NCT NCT00844480
Efficacy and Safety of Zoledronic Acid in Acute Spinal Cord Injury: Prevention of Bone Loss
Not yet reported Thomas J. Schnitzer 17 participants Est. completion 2016-01 1 siteOther conditions: Bone LossView official trial listing → -
Completed NCT NCT00869206
Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement
Not yet reported Alliance for Clinical Trials in Oncology 1822 participants Est. completion 2017-01 504 sitesOther conditions: Breast Adenocarcinoma, DS Stage I Plasma Cell Myeloma, DS Stage II Plasma Cell Myeloma, Metastatic Malignant Neoplasm to the Bone, Pain, Musculoskeletal Complication, Urinary ComplicationsView official trial listing → -
Withdrawn NCT NCT00873808
S0307A, Long-Term Bone Quality in Women With Breast Cancer Enrolled on Clinical Trial SWOG-S0307
SWOG Cancer Research Network Est. completion 2010-02 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00874211
S0702: Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone Metastases
SWOG Cancer Research Network 3571 participants Est. completion 2019-06 453 sitesOther conditions: Breast Cancer, Lung Cancer, Metastatic Cancer, Multiple Myeloma, Plasma Cell Neoplasm, Prostate Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00879034
A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria
Not yet reported Boston Children's Hospital 5 participants Est. completion 2009-04 1 siteOther conditions: Progeria, Hutchinson-Gilford SyndromeView official trial listing → -
Completed NCT NCT00885326
N2007-02:Bevacizumab,Cyclophosphamide,& Zoledronic Acid in Patients W/ Recurrent or Refractory High-Risk Neuroblastoma
Not yet reported New Approaches to Neuroblastoma Therapy Consortium 29 participants Est. completion 2019-12 15 sitesOther conditions: NeuroblastomaView official trial listing → -
Terminated NCT NCT00889590
Adjuvant Zoledronic Acid in High Risk Giant Cell Tumour of Bone (GCT)
Not yet reported Leiden University Medical Center 15 participants Est. completion 2015-07 4 sitesOther conditions: Giant Cell Tumor of Bone, OsteoclastomaView official trial listing → -
Terminated NCT NCT00892242
Perioperative Treatment With Zoledronic Acid in Patients With Resectable Pancreas Cancer
Not yet reported Washington University School of Medicine 24 participants Est. completion 2013-04 1 siteOther conditions: AdenocarcinomaView official trial listing → -
Completed NCT NCT00896532
Romosozumab (AMG 785) in Postmenopausal Women With Low Bone Mineral Density
Not yet reported Amgen 419 participants Est. completion 2016-02-18Other conditions: Low Bone Mineral Density, Postmenopausal OsteoporosisView official trial listing → -
Completed NCT NCT00903162
Extended Endocrine Therapy for Premenopausal Women With Breast Cancer
Not yet reported Dana-Farber Cancer Institute 17 participants Est. completion 2014-09 4 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00909961
A Trial Evaluating the Effects of Zoledronic Acid 5 mg Infusion on Bone Mineral Density (BMD) in Postmenopausal Osteoporosis (PMO) Patients Between the Ages of 50 and 65 Years
Not yet reported Novartis Pharmaceuticals 118 participants Est. completion 2011-12-16 6 sitesOther conditions: Postmenopausal OsteoporosisView official trial listing → -
Status unknown NCT NCT00912938
Evaluate the Relationship of Bone Remodeling Markers for Skeletal Complications in Metastatic Breast Cancer Patients
Not yet reported Korean Breast Cancer Study Group 237 participants Est. completion 2010-12 1 siteOther conditions: Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT00916747
Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria
Not yet reported Boston Children's Hospital 85 participants Est. completion 2023-12 1 siteOther conditions: ProgeriaView official trial listing → -
Completed NCT NCT00927186
Effects of Teriparatide or Zoledronic Acid Treatment on Bone in Postmenopausal Osteoporotic Women
Not yet reported Eli Lilly and Company 69 participants Est. completion 2012-04 12 sitesOther conditions: Osteoporosis, Post-menopausalView official trial listing → -
Completed NCT NCT00939900
Efficacy of Zoledronic Acid in Preventing Collapse of the Osteonecrotic Femoral Head
Not yet reported Seoul National University Bundang Hospital 110 participants Est. completion 2012-06 1 siteOther conditions: Avascular Necrosis of Femoral HeadView official trial listing → -
Completed NCT NCT00950911
Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only
Not yet reported Amgen 35 participants Est. completion 2012-04 17 sitesOther conditions: Bone Metastases in Men With Hormone-Refractory Prostate Cancer, Bone Metastases in Subjects With Advanced Breast Cancer, Bone Metastases in Subjects With Advanced Cancer or Multiple MyelomaView official trial listing → -
Terminated NCT NCT00966992
Study of Zoledronic Acid Versus Observation on Bone Mineral Density and Incidence of Micrometastasis in Women Undergoing Pelvic Radiation for Cervical Cancer
Not yet reported Washington University School of Medicine 3 participants Est. completion 2010-03 1 siteOther conditions: Uterine Cervical NeoplasmsView official trial listing → -
Completed NCT NCT00972959
Effect of Combination of Bortezomib/Dexamethasone/Zoledronic Acid on Bone Disease in Patients With Multiple Myeloma Relapsed After 1-3 Prior Lines of Therapy
Not yet reported University of Athens 17 participants Est. completion 2013-05 3 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00982124
An Efficacy and Safety Trial of Intravenous Zoledronic Acid in Infants Less Than One Year of Age, With Severe Osteogenesis Imperfecta
Not yet reported Shriners Hospitals for Children 14 participants Est. completion 2016-04 1 siteOther conditions: Osteogenesis ImperfectaView official trial listing → -
Completed NCT NCT00984893
Intra-venous Zoledronic Acid Once Yearly
Novartis Pharmaceuticals 1551 participants Est. completion 2014-04 3 sitesOther conditions: Post-Menopausal OsteoporosisView official trial listing → -
Completed NCT NCT00987636
Study in Localized and Disseminated Ewing Sarcoma
Not yet reported University Hospital Muenster 907 participants Est. completion 2019-03-31 2 sitesOther conditions: Ewing's SarcomaView official trial listing → -
Terminated NCT NCT01004510
Zometa Adjuvant Treatment of Malignant Pleural Effusion Due To Non-Small Cell Lung Cancer
Not yet reported Peter Bushunow MD 3 participants Est. completion 2011-04 1 siteOther conditions: Malignant Pleural Effusion, Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT01006395
Prevention of Micro-architectural Bone Decay in Males With Non-metastatic Prostate Cancer Receiving Androgen Deprivation Therapy (ADT)
Not yet reported, Not yet reported Austin Health 64 participants Est. completion 2019-04 1 siteOther conditions: Prostate CancerView official trial listing → -
Status unknown NCT NCT01016093
Zoledronic Acid for the Prevention of Bone Loss Post-bone Marrow Transplantation for Thalassemia Major Patients
Not yet reported, Not yet reported Tehran University of Medical Sciences 50 participants Est. completion 2011-12 1 siteOther conditions: Beta-Thalassemia, Bone Marrow TransplantationView official trial listing → -
Completed NCT NCT01062503
Duration of Suppression of Bone Turnover Following Treatment With Zoledronic Acid in Men With Metastatic CRPC
University Health Network, Toronto 48 participants Est. completion 2014-06 1 siteOther conditions: Metastatic Prostate Cancer, Bone MetastasisView official trial listing → -
Terminated NCT NCT01067989
Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast Cancer
Not yet reported HaEmek Medical Center, Israel 22 participants Est. completion 2014-04 1 siteOther conditions: Chemotherapy, Breast Cancer, MetastaticView official trial listing → -
Completed NCT NCT01087008
Zoledronic Acid in Patients With Multiple Myeloma and Asymptomatic Biochemical Relapse
Not yet reported PETHEMA Foundation 103 participants Est. completion 2013-06-05 16 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT01099436
Neo-Adjuvant Chemotherapy (TAC) With or Without Zoledronic Acid in Treating HER2-negative Breast Cancer Patients
Not yet reported Borstkanker Onderzoek Groep 250 participants Est. completion 2013-09 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01129336
Effect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer Patients
Not yet reported Novartis Pharmaceuticals 44 participants Est. completion 2012-08 33 sitesOther conditions: First or Second Line HER2-negative Breast Cancer, Metastatic Disease Without Bone MetastasisView official trial listing → -
Completed NCT NCT01153425
µMRI of Therapeutic Intervention in Postmenopausal Osteoporosis
Not yet reported University of Pennsylvania 33 participants Est. completion 2012-12 1 siteOther conditions: Osteoporosis, OsteopeniaView official trial listing → -
Terminated NCT NCT01166178
Zoledronic Acid in MS-patients With Osteoporosis
Not yet reported Novartis 29 participants Est. completion 2012-06 15 sitesOther conditions: Osteoporosis, Multiple SclerosisView official trial listing → -
Completed NCT NCT01194440
Zoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal Symptoms
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 63 participants Est. completion 2014-01 1 siteOther conditions: Ductal Carcinoma in Situ, Estrogen Receptor-positive Breast Cancer, Progesterone Receptor-positive Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast CancerView official trial listing → -
Completed NCT NCT01197300
1 Year Open-label Extension to CZOL446H2337 Safety and Efficacy Trial of Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids
Not yet reported Novartis Pharmaceuticals 25 participants Est. completion 2019-02-27 10 sitesOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT01204203
Pilot Study of Bisphosphonate Therapy (Zoledronic Acid) in Patients With Malignant Mesothelioma (UAB 0901)
Not yet reported University of Alabama at Birmingham 8 participants Est. completion 2016-04 1 siteOther conditions: MesotheliomaView official trial listing → -
Completed NCT NCT01205646
PET Scanning to Evaluate Zoledronate Efficacy in Metastatic Prostate Cancer
Not yet reported Barbara Ann Karmanos Cancer Institute 11 participants Est. completion 2015-08 2 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT01215344
First Autologous Transplant on Minimal Residual Disease Markers in Previously Untreated Myeloma Undergoing Initial Treatment With Velcade
Not yet reported Vanderbilt-Ingram Cancer Center 36 participants Est. completion 2018-03 2 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT01218035
Efficacy of Zoledronic Acid in Enhancement of Early Stability of Cementless Primary Hip Prosthesis
Not yet reported Turku University Hospital 49 participants Est. completion 2011-06 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT01219790
ZOLEDRONIC ASSOCIATED With Hight Hypofractionated Radiotherapy Dose in Bone Metastases Vertebral Prostate Adenocarcinoma
Not yet reported Institut Cancerologie de l'Ouest 30 participants Est. completion 2015-11 3 sitesOther conditions: Prostate AdenocarcinomaView official trial listing → -
Completed NCT NCT01228318
Bone Loss and Immune Reconstitution in HIV/AIDS (BLIR-HIV)
Not yet reported Emory University 63 participants Est. completion 2017-04-13 1 site Stand-aloneOther conditions: HIV Infection, Bone Loss, Osteopenia, OsteoporosisView official trial listing → -
Completed NCT NCT01234129
Stem Cell Transplant and Zoledronic Acid Improve Outcome in Previously Untreated Patients With Multiple Myeloma
Instituto Mexicano del Seguro Social 320 participants Est. completion 2009-12 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT01259193
Clinical Study of Sorafenib and Zoledronic Acid to Treat Advanced HCC
Not yet reported Fudan University 50 participants Est. completion 2012-07 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT01267279
Effect of Zoledronic Acid on Femoral Bone Loss Following Total Hip Arthroplasty
Not yet reported Spokane Joint Replacement Center 51 participants Est. completion 2014-12Other conditions: OsteoporosisView official trial listing → -
Status unknown NCT NCT01310465
The Effect of Zoledronic Acid to Bone Fusion and Bone Metabolism of Patients With Lumbar Degenerative Disease After Lumbar Interbody Fusion
Not yet reported Fudan University 50 participants Est. completion 2012-04 1 siteOther conditions: Image Changes of Lumbar Fusion, Bone Turnover Markers, Bone Mineral DensityView official trial listing → -
Completed NCT NCT01330238
The Efficacy of Zoledronic Acid in Modic Changes-related Low Back Pain (LBP)
Not yet reported University of Oulu 40 participants Est. completion 2012-03 1 siteOther conditions: Low Back PainView official trial listing → -
Withdrawn NCT NCT01332617
Phase II Study of Simvastatin for Relapsed/Refractory Myeloma
Not yet reported University of Louisville Est. completion 2019-02Other conditions: MyelomaView official trial listing → -
Completed NCT NCT01341262
THAL-DEX Incorporated Into Double PBSC Autotransplantation for Untreated Multiple Myeloma (MM)
Not yet reported IRCCS Azienda Ospedaliero-Universitaria di Bologna 378 participants Est. completion 2009-01Other conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT01344967
Suppression of Bone Turnover Following Treatment With Zoledronic Acid in Patients With Metastatic Breast Cancer: Duration of Effect
Not yet reported, Not yet reported University Health Network, Toronto 21 participants Est. completion 2011-12 1 siteOther conditions: Metastatic Breast Cancer With Bone InvolvementView official trial listing → -
Completed NCT NCT01345019
Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma
Not yet reported Amgen 1718 participants Est. completion 2019-03-29 309 sitesOther conditions: Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology, Bone Metastases, Multiple Myeloma Bone LesionsView official trial listing → -
Completed NCT NCT01348269
Assessment of Efficacy of Zoledronic Acid in the Treatment of Bone Marrow Edema Syndrome
Not yet reported Wuerzburg University Hospital 48 participants Est. completion 2015-08-26 2 sitesOther conditions: Bone Marrow EdemaView official trial listing → -
Completed NCT NCT01367288
Comparative Study of Neoadjuvant Chemotherapy With and Without Zometa for Management of Locally Advanced Breast Cancers
Not yet reported Hospices Civils de Lyon 53 participants Est. completion 2014-04 1 siteOther conditions: Locally Advanced Breast Cancer, Ductal Histologic Type, Without Her 2 OverexpressionView official trial listing → -
Terminated NCT NCT01404702
Pilot Study of Zoledronic Acid and Interleukin-2 for Refractory Pediatric Neuroblastoma
Not yet reported University of Alabama at Birmingham 4 participants Est. completion 2014-08 1 siteOther conditions: NeuroblastomaView official trial listing → -
Terminated NCT NCT01409811
Biomarkers in Tissue Samples From Patients With Newly Diagnosed Breast Cancer Treated With Zoledronic Acid
Not yet reported City of Hope Medical Center 9 participants Est. completion 2015-02 1 siteOther conditions: Estrogen Receptor-positive Breast Cancer, Invasive Ductal Breast Carcinoma, Progesterone Receptor-positive Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast CancerView official trial listing → -
Terminated NCT NCT01426555
FES-Rowing Versus Zoledronic Acid to Improve Bone Health in Spinal Cord Injury (SCI)
Not yet reported, Not yet reported Antonio Lazzari 70 participants Est. completion 2015-02 2 sitesOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT01472146
ZoNantax - Zolendronic Acid as Neoadjuvant Therapy Plus Anthracycline and Taxane in Locally Advanced Breast Cancer
Not yet reported Susanne Crocamo 58 participants Est. completion 2017-05 1 siteOther conditions: Breast Cancer, Breast Disease, Neoplasms, Neoplasms by SiteView official trial listing → -
Completed NCT NCT01488851
Study to Assess Incidence of ONJ in Pts With Bone Mets Starting Zoledronic Acid Treatment
King Faisal Specialist Hospital & Research Center 100 participants Est. completion 2015-01 1 siteOther conditions: CancerView official trial listing → -
Completed NCT NCT01522521
Study of AK156 in Primary Osteoporosis Patients
Not yet reported Asahi Kasei Therapeutics Corporation 600 participants Est. completion 2015-01 20 sitesOther conditions: OsteoporosisView official trial listing → -
Terminated NCT NCT01564121
Study of the Effect of Zoledronate on Local Recurrence After Surgical Treatment of Giant Cell Tumors of Bone Zométa
Not yet reported, Not yet reported Nantes University Hospital 24 participants Est. completion 2011-01 1 siteOther conditions: Giant Cell Tumors of BoneView official trial listing → -
Completed NCT NCT01572545
Comparative Effect of Zoledronic Acid Versus Denosumab on Serum Sclerostin of Postmenopausal Women With Low Bone Mass
Not yet reported Aristotle University Of Thessaloniki 91 participants Est. completion 2013-01 3 sitesOther conditions: Postmenopausal OsteoporosisView official trial listing → -
Terminated NCT NCT01623908
Bone Loss Treatment From Adjuvant Zoledronate Efficacy
Not yet reported First Affiliated Hospital, Sun Yat-Sen University 200 participants Est. completion 2013-06 10 sitesOther conditions: Breast Neoplasms, Bone LossView official trial listing → -
Completed NCT NCT01642901
Zoledronic Acid in Acute Spinal Cord Injury
Not yet reported Thomas Jefferson University 16 participants Est. completion 2018-03 1 siteOther conditions: Spinal Cord InjuryView official trial listing → -
Status unknown NCT NCT01654367
Research of Zoledronic Acid and Aromatase Inhibitors as Adjuvant Therapy to Breast Cancer
Not yet reported, Not yet reported Tianjin Medical University 300 participants Est. completion 2013-12 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01656512
Zometa Study in Pediatric Acute Lymphoblastic Leukemia
Not yet reported Children's Cancer Hospital Egypt 57357 95 participants Est. completion 2015-08 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT01671774
Safety and Activity of IMAB362 in Combination With Zoledronic Acid and Interleukin-2 in CLDN18.2-positive Gastric Cancer
Not yet reported Astellas Pharma Global Development, Inc. 29 participants Est. completion 2014-10-13 9 sitesOther conditions: CLDN18.2-positive Gastric Adenocarcinoma, CLDN18.2-positive Adenocarcinoma of the Gastroesophageal Junction, CLDN18.2-positive Adenocarcinoma of EsophagusView official trial listing → -
Completed NCT NCT01675089
Zoledronic Acid to Prevent Bone Loss After Kidney Transplantation
Not yet reported University of Sao Paulo General Hospital 34 participants Est. completion 2014-05 1 siteOther conditions: Renal OsteodystrophyView official trial listing → -
Terminated NCT NCT01679080
The Effect of Treatment With Teriparatide and Zoledronic Acid in Patients With Osteogenesis Imperfecta
Not yet reported University of Aarhus 9 participants Est. completion 2021-06-01 3 sitesOther conditions: Osteogenesis ImperfectaView official trial listing → -
Withdrawn NCT NCT01702415
Zoledronic Acid in Cystic Fibrosis
Not yet reported Papworth Hospital NHS Foundation Trust Est. completion 2015-12 1 siteOther conditions: Cystic FibrosisView official trial listing → -
Completed NCT NCT01721993
Open Label Dose Escalation Phase I Study to Investigate the Safety and Pharmacokinetics of T121E01F and T121E02F in Healthy Postmenopausal Women
Not yet reported Thar Pharmaceuticals, Inc 71 participants Est. completion 2014-08 1 siteOther conditions: Healthy Postmenopausal WomenView official trial listing → -
Completed NCT NCT01732770
Safety and Efficacy Study to Evaluate Denosumab Compared With Zoledronic Acid in Postmenopausal Women With Osteoporosis
Not yet reported Amgen 643 participants Est. completion 2015-01-07 45 sitesOther conditions: Post Menopausal OsteoporosisView official trial listing → -
Status unknown NCT NCT01737216
Pilot Study of Zoledronic Acid in Combination With First-line Chemotherapy in Aged Patients With Lung Cancer
Not yet reported Hebei Tumor Hospital 100 participants Est. completion 2016-12 1 siteOther conditions: Lung CancerView official trial listing → -
Terminated NCT NCT01772719
Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic Acid
Not yet reported University of Louisville 7 participants Est. completion 2016-11 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT01788176
The Use of Zoledronic Acid to Complex Regional Pain Syndrome
Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2016-12 1 siteOther conditions: Complex Regional Pain SyndromesView official trial listing → -
Terminated NCT NCT01802658
Bone Demineralization Lesions in the Injured Marrow: Efficacy and Tolerability of Administration Early and Repeated the Zoledronic Acid. Comparative Study, Prospective, Double-blind Controlled (DBMZol)
Not yet reported Nantes University Hospital 12 participants Est. completion 2016-12 9 sitesOther conditions: Bone Demineralization Lesions in the Injured MarrowView official trial listing → -
Completed NCT NCT01875458
Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use
University of Pennsylvania 314 participants Est. completion 2022-10-30 1 siteOther conditions: Osteoporosis, With or Without Treatment, Bisphosphonate Treatment, Atypical Femur Fracture, Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Healthy VolunteersView official trial listing → -
Completed NCT NCT01907880
The ODYSSEY TRIAL Phase IV Trial Evaluating the Palliative Benefit of Pamidronate or Zoledronic Acid in Breast Cancer
Not yet reported Ottawa Hospital Research Institute 74 participants Est. completion 2016-01 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01920568
A Study to Compare Denosumab With Zoledronic Acid in Subjects With Bone Metastases From Solid Tumors
Not yet reported GlaxoSmithKline 487 participants Est. completion 2016-04 25 sitesOther conditions: Fractures, BoneView official trial listing → -
Completed NCT NCT01951586
Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer
Not yet reported Amgen 226 participants Est. completion 2017-11-28 74 sitesOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT01967160
Osteonecrosis of the Jaw (ONJ) and Infection Among Nordic Cancer Patients Treated With XGEVA™ or Zoledronic Acid
Amgen 2560 participants Est. completion 2019-08-05Other conditions: Osteonecrosis of the Jaw, Infection Leading to HospitalizationView official trial listing → -
Completed NCT NCT02042872
Zoledronic Acid Administration in Acute Spinal Cord Injury
Not yet reported James J. Peters Veterans Affairs Medical Center 21 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Disuse OsteoporosisView official trial listing → -
Status unknown NCT NCT02044978
Initial Fixation of Bisphosphonate-coated Dental Implants
Not yet reported Per Aspenberg 16 participants Est. completion 2017-01 2 sitesOther conditions: Pre-integration Failure of Dental ImplantView official trial listing → -
Withdrawn NCT NCT02069340
Genetics in Predicting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid
Not yet reported University of Southern California Est. completion 2021-06 2 sitesOther conditions: Malignant Neoplasm, Musculoskeletal ComplicationsView official trial listing → -
Terminated NCT NCT02123264
Zoledronic Acid in Rheumatoid Arthritis
Not yet reported Carmen Gómez-Vaquero 28 participants Est. completion 2018-06 11 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT02176382
Denosumab and Teriparatide Study (DATA-HD and DATA-EX)
Not yet reported Massachusetts General Hospital 76 participants Est. completion 2020-02 1 siteOther conditions: Postmenopausal OsteoporosisView official trial listing → -
Completed NCT NCT02181101
Simultaneous Study of Gemcitabine-Docetaxel Combination Adjuvant Treatment, as Well as Extended Bisphosphonate and Surveillance-Trial
Not yet reported Ludwig-Maximilians - University of Munich 3754 participants Est. completion 2013-09 1 siteOther conditions: Breast NeoplasmsView official trial listing → -
Completed NCT NCT02274623
Effect of CTAP101 Capsules on Ca/iPTH in Advanced Breast/Prostate Cancer Patients Treated With Denosumab/Zoledronic Acid
Not yet reported OPKO Health, Inc. 33 participants Est. completion 2017-03-17 6 sitesOther conditions: Breast Cancer, Prostate Cancer, Bone Neoplasms, Hypocalcemia, Hyperparathyroidism, SecondaryView official trial listing → -
Completed NCT NCT02286830
Prolonged Protection From Bone Disease in Multiple Myeloma
Not yet reported Thomas Lund 158 participants Est. completion 2023-02-16 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT02325414
Prevention of Bone Loss After Acute SCI by Zoledronic Acid
Not yet reported Northwestern University 60 participants Est. completion 2020-08-25 2 sitesOther conditions: Spinal Cord Injury, Acute Spinal Cord Injury, Bone Loss, OsteoporosisView official trial listing → -
Withdrawn NCT NCT02333344
The Efficacy Study of Aclasta on Prosthetic Fixation in Postmenopausal Women After THA
Not yet reported Novartis Pharmaceuticals Est. completion 2020-01-28 1 siteOther conditions: Prosthetic Fixation After Cementless Total Hip ArthroplastyView official trial listing → -
Terminated NCT NCT02347163
Pre-operative Zoledronate in Triple Negative Breast Cancer
Not yet reported Mario Negri Institute for Pharmacological Research 22 participants Est. completion 2018-06-08 4 sitesOther conditions: Breast CancerView official trial listing → -
Withdrawn NCT NCT02451462
Pilot Trial of Zoledronic Acid to Prevent Bone Loss in Hematopoietic Cell Transplant Recipients
Not yet reported Stanford University Est. completion 2018-09Other conditions: Hematopoietic Stem Cell Transplant, Bone Marrow TransplantView official trial listing → -
Status unknown NCT NCT02480634
Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer
Not yet reported Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 280 participants Est. completion 2022-12Other conditions: Non-small Cell Lung Cancer, Bone MetastasisView official trial listing → -
Completed NCT NCT02499237
Zoledronic Acid to Maintain Bone Mass After Denosumab Discontinuation
Not yet reported 424 General Military Hospital 57 participants Est. completion 2018-11-26 2 sitesOther conditions: Postmenopausal OsteoporosisView official trial listing → -
Status unknown NCT NCT02504008
CREATE-1: A Study to Assess the Efficacy and Safety of AXS-02 in Patients With CRPS-1
Not yet reported Axsome Therapeutics, Inc. 190 participants Est. completion 2019-01 44 sitesOther conditions: Complex Regional Pain Syndrome, Reflex Sympathetic DystrophyView official trial listing → -
Terminated NCT NCT02516423
Ixazomib Citrate, Lenalidomide, Dexamethasone, and Zoledronic Acid or Zoledronic Acid Alone After Radiation Therapy in Treating Patients With Solitary Plasmacytoma of Bone
Not yet reported Alliance for Clinical Trials in Oncology 11 participants Est. completion 2025-09-30 388 sitesOther conditions: Solitary Osseous PlasmacytomaView official trial listing → -
Completed NCT NCT02517918
Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma
Not yet reported Institut Bergonié 23 participants Est. completion 2021-11-16 3 sitesObstructive sleep apnea Other conditions: Solid TumorView official trial listing → -
Completed NCT NCT02520362
Denosumab Safety Assessment in Multiple Observational Databases
Amgen 517991 participants Est. completion 2023-07-21Other conditions: OsteoporosisView official trial listing → -
Completed NCT NCT02589600
Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)
Not yet reported Susan L. Greenspan 310 participants Est. completion 2022-06-22 1 site Stand-aloneOther conditions: Osteoporotic Fractures, Osteoporosis, PostmenopausalView official trial listing → -
Status unknown NCT NCT02595138
Zoledronic Acid as Adjuvant Treatment of Triple-negative Breast Cancer
Not yet reported Chinese Academy of Medical Sciences 430 participants Est. completion 2023-12Other conditions: Triple Negative Breast CancerView official trial listing → -
Status unknown NCT NCT02622607
Preventive Effects of Zoledronic Acid on Bone Metastasis in Patients With Stage IIIB and IV Lung Cancer
Not yet reported Tang-Du Hospital 200 participants Est. completion 2018-03 1 siteOther conditions: Lung CancerView official trial listing → -
Withdrawn NCT NCT02632903
Intravenous Zoledronic Acid for the Treatment of Osteoporosis and Osteonecrosis in Children With Leukemia: A Pilot Study
Not yet reported Children's Hospital of Eastern Ontario Est. completion 2018-08-20 1 siteOther conditions: Osteoporosis, Osteonecrosis, Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02632916
Denosumab for the Treatment of Osteoporosis in Children: A Pilot Study
Not yet reported Children's Hospital of Eastern Ontario 10 participants Est. completion 2020-02-03 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT02721433
4-weekly Versus 12-weekly Administration of Bone-targeted Agents in Patients With Bone Metastases
Not yet reported Ottawa Hospital Research Institute 263 participants Est. completion 2020-04 1 siteOther conditions: Breast Cancer, Prostate Cancer, MetastasisView official trial listing → -
Status unknown NCT NCT02721940
Mononuclear Cells, Platelets and Zoledronic Acid for Preventing Collapse of the Femoral Head in Osteonecrosis
Not yet reported Chinese PLA General Hospital 100 participants Est. completion 2016-05Other conditions: OsteonecrosisView official trial listing → -
Completed NCT NCT02731040
Exome Sequencing for Atypical Femoral Fractures
Washington University School of Medicine 38 participants Est. completion 2018-03-29Other conditions: Atypical Femoral Fractures, Osteoporosis, Bisphosphonate TherapyView official trial listing → -
Terminated NCT NCT02739555
Zoledronic Acid Compared to Percutaneous Treatment in Osteoid Osteoma
Not yet reported Assistance Publique - Hôpitaux de Paris 15 participants Est. completion 2019-06-28 16 sitesOther conditions: Osteoid OsteomaView official trial listing → -
Terminated NCT NCT02739594
Comparison of Ibandronate - Zoledronate Regarding Nephrotoxicity in Multiple Myeloma
Not yet reported Hoffmann-La Roche 89 participants Est. completion 2009-04 56 sitesOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT02746068
A Study to Assess the Efficacy and Safety of AXS-02 in Subjects With Knee OA Associated With Bone Marrow Lesions
Not yet reported Axsome Therapeutics, Inc. 346 participants Est. completion 2020-12 61 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT02784652
Efficacy of Radiotherapy in Combination With Zoledronic Acid in Bone Metastasis Patients With Gastrointestinal Tumors
Not yet reported Severance Hospital 60 participants Est. completion 2017-02-28 1 siteOther conditions: Bone Metastasis, Gastrointestinal CancerView official trial listing → -
Completed NCT NCT02808988
Changes of GCF Levels of RANKL and Osteoprotegerin in Postmenopausal Osteoporosis
Not yet reported Ondokuz Mayıs University 47 participants Est. completion 2015-11Other conditions: Chronic PeriodontitisView official trial listing → -
Completed NCT NCT02823925
Bisphosphonate Therapy in MONA Spectrum Disorder
Medical University Innsbruck 3 participantsOther conditions: Bone Density, Pain, FractureView official trial listing → -
Completed NCT NCT02838121
Prevention of Periprosthetic Bone Loss After Total Hip Replacement by Annual Bisphosphonate Therapy
Not yet reported Mel Shiuann-Sheng Lee 62 participants Est. completion 2016-06 1 siteOther conditions: Prevention of BMD Loss After THR, Serum Markers of Bone Turnover, Functional OutcomesView official trial listing → -
Terminated NCT NCT03040765
Denosumab Versus Zoledronic Acid in Thalassemia-Induced Osteoporosis
Not yet reported Hamad Medical Corporation 17 participants Est. completion 2019-04-08 1 siteOther conditions: Thalassemia Majors (Beta-Thalassemia Major), OsteoporosisView official trial listing → -
Active, not recruiting NCT NCT03073785
Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic Cancer
Not yet reported University of Nebraska 46 participants Est. completion 2027-12 1 siteOther conditions: Pancreatic Adenocarcinoma, Recurrent Pancreatic Carcinoma, Stage I Pancreatic Cancer AJCC v6 and v7, Stage IA Pancreatic Cancer AJCC v6 and v7, Stage IB Pancreatic Cancer AJCC v6 and v7, Stage II Pancreatic Cancer AJCC v6 and v7, Stage IIA Pancreatic Cancer AJCC v6 and v7, Stage IIB Pancreatic Cancer AJCC v6 and v7, Stage III Pancreatic Cancer AJCC v6 and v7, Stage IV Pancreatic Cancer AJCC v6 and v7View official trial listing → -
Completed NCT NCT03087851
Treatment With Zoledronic Acid Subsequent to Denosumab in Osteoporosis
Not yet reported Aarhus University Hospital 61 participants Est. completion 2020-08-01 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT03118570
A Study in Adult Patients With Type I, III or IV Osteogenesis Imperfecta Treated With BPS804
Not yet reported Ultragenyx Pharmaceutical Inc 112 participants Est. completion 2020-11-12 25 sitesOther conditions: Osteogenesis Imperfecta, Type I, Osteogenesis Imperfecta Type III, Osteogenesis Imperfecta Type IVView official trial listing → -
Status unknown NCT NCT03158246
Generic Zoledronic Acid Versus Original Zoledronic Acid in Postmenopausal Osteoporotic Women
Not yet reported Cttq 466 participants Est. completion 2020-03-02Other conditions: Osteoporosis, PostmenopausalView official trial listing → -
Status unknown NCT NCT03169192
Diagnosis of Osteogenesis Imperfecta in Children
Assiut University 40 participants Est. completion 2019-03-01 1 siteOther conditions: Bone Disease, MetabolicView official trial listing → -
Active, not recruiting NCT NCT03173976
Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial
Not yet reported Mohammed Milhem 17 participants Est. completion 2028-05-01 1 siteObstructive sleep apneaView official trial listing → -
Status unknown NCT NCT03183557
Efficacy of Zoledronic Acid in Osteoporosis
Not yet reported Shinshu University 100 participants Est. completion 2025-06-08 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT03289338
Zoledronic Acid or Methylprednisolone for Active Charcot's Neuroarthropathy of Foot in Patients With Diabetes Mellitus
Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 36 participants Est. completion 2018-12-31 1 siteOther conditions: Charcot Arthropathy, Diabetes ComplicationsView official trial listing → -
Completed NCT NCT03301285
Efficacy of Zoledronic Acid in Osteoporosis of Children With Multiple Disabilities
Central Hospital, Nancy, France 60 participants Est. completion 2017-03-31 1 siteOther conditions: Multiple Disability, OsteoporosisView official trial listing → -
Completed NCT NCT03336983
Luteinizing Hormone-releasing Hormone Analogue and Enzalutamide +/- Zoledronic Acid in Prostate Cancer Patients
Not yet reported Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 126 participants Est. completion 2023-04-01 1 siteOther conditions: Prostate Cancer, Bone MetastasesView official trial listing → -
Completed NCT NCT03358017
Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer
Not yet reported Mario Negri Institute for Pharmacological Research 54 participants Est. completion 2023-07-25 9 sitesOther conditions: Triple Negative Breast CancerView official trial listing → -
Completed NCT NCT03396315
Bisphosphonates for Prevention of Post-Denosumab Bone Loss
Not yet reported Columbia University 24 participants Est. completion 2023-06-09 2 sitesOther conditions: IOP, OsteoporosisView official trial listing → -
Terminated NCT NCT03408652
Efficacy and Safety of Systemic Treatments of Bone Metastases From Kidney Cancer in Patients Treated With Targeted Therapies
Not yet reported Centre Leon Berard 1 participants Est. completion 2020-06-22 1 siteOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT03424239
Pilot Study for Zoledronic Acid to Prevent Bone Loss After Bariatric Surgery
Not yet reported Massachusetts General Hospital 6 participants Est. completion 2020-01-01 1 siteOther conditions: Bariatric Surgery CandidateView official trial listing → -
Terminated NCT NCT03576599
Intravenous Bisphosphonate in Stress Fracture Treatment -A Randomised Controlled Double Blinded Multicenter Trial
Not yet reported Oslo University Hospital 5 participants Est. completion 2019-06-26 1 siteOther conditions: Stress Fracture Foot, Stress Fracture AnkleView official trial listing → -
Completed NCT NCT03664687
Comparing a Single-Dose vs. Twice Yearly Zoledronate in Patients With Early Stage Breast Cancer (REaCT-ZOL)
Not yet reported Ottawa Hospital Research Institute 211 participants Est. completion 2025-03-28 6 sitesOther conditions: Early-stage Breast CancerView official trial listing → -
Completed NCT NCT03735537
Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic Acid
Not yet reported University of Edinburgh 350 participants Est. completion 2025-03-21 23 sitesOther conditions: Osteogenesis ImperfectaView official trial listing → -
Withdrawn NCT NCT03812367
Activity of Pre-Osteoclasts and Osteoclasts Over Time in Postmenopausal Women Treated With Denosumab or Zoledronic Acid
University of California, Davis Est. completion 2021-12-31 1 siteOther conditions: Osteoporosis, PostmenopausalView official trial listing → -
Enrolling by invitation NCT NCT03859895
Zoledronate In the Prevention of Paget's Disease: Long Term Extension
University of Edinburgh 287 participants Est. completion 2027-05 21 sitesOther conditions: Paget DiseaseView official trial listing → -
Completed NCT NCT03862833
Zoledronic Acid in Combination With Interleukin-2 to Expand Vγ9Vδ2 T Cells After T-replete Haplo-identical Allotransplant
Not yet reported Nantes University Hospital 30 participants Est. completion 2023-08-29 1 siteOther conditions: Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT03868033
Denosumab Sequential Therapy
Not yet reported National Taiwan University Hospital 101 participants Est. completion 2023-12-31 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT03924414
Trial of Parkinson's And Zoledronic Acid
Not yet reported California Pacific Medical Center Research Institute 2721 participants Est. completion 2026-02-28 77 sitesOther conditions: Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia With Lewy BodiesView official trial listing → -
Completed NCT NCT03930992
Efficacy of Zoledronic Acid + Colaren vs Zoledronic Acid + Conventional Treatment for Osteoporosis in HIV+ and HIV- Men
Not yet reported University of Guadalajara 30 participants Est. completion 2022-10-31 1 siteOther conditions: Secondary OsteoporosisView official trial listing → -
Status unknown NCT NCT03932071
Zoledronic Acid in Decrease the Lung Metastatic Rate of Osteosarcoma
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 150 participants Est. completion 2023-01-01 1 siteOther conditions: Lung Metastases, Tumor NecrosisView official trial listing → -
Status unknown NCT NCT03951493
Multicentre Medical-economic Study Evaluating the Efficacy of Adding ZOlédronique Acid to STERéotaxique Radiotherapy in the Treatment of Vertebral Metastases
Not yet reported Institut Cancerologie de l'Ouest 225 participants Est. completion 2023-11-01 7 sitesOther conditions: Vertebral MetastasisView official trial listing → -
Completed NCT NCT04012320
Efficacy and Safety on the Use of Bisphosphonates in Paediatrics
Centre Hospitalier Universitaire de Nīmes 99 participants Est. completion 2018-12-31 1 siteOther conditions: Bone Fragile, Bisphosphonate-Associated Osteonecrosis, Children, Adverse EventsView official trial listing → -
Status unknown NCT NCT04034199
Treating Idiopathic Inflammatory Myopathies Related Reduced Bone Mineral Density With Denosumab or Zoledronic Acid
Not yet reported Kwong Wah Hospital 40 participants Est. completion 2021-03-31 1 siteOther conditions: Idiopathic Inflammatory Myopathies, Osteoporosis, OsteopeniaView official trial listing → -
Status unknown NCT NCT04045522
Study on Bisphosphonates Targeting Triple-negative Breast Cancer
Shengjing Hospital 120 participants Est. completion 2022-08-31 3 sitesOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT04085419
Osteoporosis in Primary Hyperparathyroidism
Not yet reported University Medical Centre Ljubljana 40 participants Est. completion 2023-05 1 siteOther conditions: Primary Hyperparathyroidism, OsteoporosisView official trial listing → -
Completed NCT NCT04087096
Denosumab to Prevent High-Turnover Bone Loss After Bariatric Surgery
Not yet reported Massachusetts General Hospital 36 participants Est. completion 2024-08-06 2 sitesOther conditions: Bariatric Surgery Candidate, Bone LossView official trial listing → -
Status unknown NCT NCT04115397
Bisphosphonates for the Treatment of Seropositive Musculoskeletal Complaints
Not yet reported Karolinska Institutet 80 participants Est. completion 2022-12Other conditions: Seropositive Muskuloskeletal ComplaintsView official trial listing → -
Completed NCT NCT04149405
Alterations of GCF Levels of Sclerostin and DKK-1 in Postmenopausal Osteoporosis
Not yet reported Ondokuz Mayıs University 43 participants Est. completion 2018-12-28Other conditions: Osteoporosis, Postmenopausal, PeriodontitisView official trial listing → -
Completed NCT NCT04177940
Denosumab (DMAB) Discontinuation And Switching In Glucocorticoid-Induced Osteoporosis (GIOP): A Pilot Study
Not yet reported University of Alabama at Birmingham 45 participants Est. completion 2025-01-14 1 siteOther conditions: OsteoporosisView official trial listing → -
Withdrawn NCT NCT04253340
Study of a Bone Assessment Technique, Bone Mineral Analyser, Concerning the Prediction of Improvement in Bone Status After an Infusion of Zoledronic Acid in Osteoporotic Women
Not yet reported University Hospital, Rouen Est. completion 2023-03-01Other conditions: OsteoporosisView official trial listing → -
Completed NCT NCT04279392
Healthy Body, Healthy Bones After Bariatric Surgery Trial
Not yet reported, Not yet reported University of Nebraska 10 participants Est. completion 2022-12-30 1 siteOther conditions: Bariatric Surgery Candidate, Bone Loss, Bone ResorptionView official trial listing → -
Status unknown NCT NCT04303026
The Effect of Zoledronic Acid on Patients With Osteoarthritis of the Hip
Not yet reported Vestre Viken Hospital Trust 70 participants Est. completion 2024-06-30 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT04304755
Zoledronic Acid as Adjuvant Therapy in Neovascular Age-related Macular Degeneration (Z-AMD)
Not yet reported Oslo University Hospital 40 participants Est. completion 2024-01-24 2 sitesOther conditions: Neovascular Age-related Macular DegenerationView official trial listing → -
Status unknown NCT NCT04325776
A Study of AL2846 Versus Zoledronic Acid in Subjects With Advanced Non-Small Cell Lung Cancer With Bone Metastasis
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 60 participants Est. completion 2021-11 8 sitesOther conditions: Bone Metastatic Non-small Cell Lung CancerView official trial listing → -
Enrolling by invitation NCT NCT04488614
Prospective Breast Cancer Biobanking
Helse Stavanger HF 1200 participants Est. completion 2030-07-15 2 sitesOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT04498715
Trochanteric Femur Fracture Operated With Dynamic Hip Screw System (DHS) Augmented With a Biphasic Apatite Sulphate Combined With Systemic or Local Bisphosphonate
Not yet reported Lithuanian University of Health Sciences 20 participants Est. completion 2024-12 1 siteOther conditions: Trochanteric Fracture of FemurView official trial listing → -
Active, not recruiting NCT NCT04549207
Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients Treated for Over 2 Years for Bone Metastases From Either Breast or Castration-resistant Prostate Cancer
Not yet reported Ottawa Hospital Research Institute 240 participants Est. completion 2026-09 5 sitesOther conditions: Breast Cancer, Castration-resistant Prostate CancerView official trial listing → -
Status unknown NCT NCT04597931
Evaluation of Romosozumab vs. Zoledronic Acid Effect in Patients With Spinal Cord Injury and Low Bone Mineral Density
Not yet reported Sheba Medical Center 30 participants Est. completion 2023-11-15Other conditions: Osteoporosis Fracture, Spinal Cord InjuriesView official trial listing → -
Status unknown NCT NCT04652128
Effect of Zoledronic Acid on Prevention of Bone Loss in Acute Phase First-ever Stroke Patients
Not yet reported Yonsei University 56 participants Est. completion 2023-02 1 siteCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT04719481
Pravastatin Reduces Acute Phase Response of Zoledronic Acid
Not yet reported Peking University Third Hospital 110 participants Est. completion 2022-04Other conditions: Postmenopausal OsteoporosisView official trial listing → -
Status unknown NCT NCT04719572
Intervention Study of Drugs in Patients Osteopenia and Osteoporosis
Not yet reported Chinese PLA General Hospital 180 participants Est. completion 2023-01 1 siteOther conditions: Osteoporosis, Osteopenia, OsteoporosisView official trial listing → -
Status unknown NCT NCT04719650
Clinical Pharmacokinetics and Pharmacodynamics Study of Different Doses of Zoledronic Acid
Not yet reported Peking University Third Hospital 64 participants Est. completion 2024-11Other conditions: Postmenopausal OsteoporosisView official trial listing → -
Completed NCT NCT04736693
Replication of the HORIZON Pivotal Fracture Trial in Healthcare Claims Data
Brigham and Women's Hospital 18028 participants Est. completion 2021-02-18 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT04742010
Zoledronic Acid for Prevention of Bone Loss After BAriatric Surgery (ZABAS)
Not yet reported Stinus Gadegaard Hansen 59 participants Est. completion 2024-08-12 1 siteOther conditions: Bone Loss, Muscle Atrophy, Bariatric SurgeryView official trial listing → -
Completed NCT NCT04779216
Effects of Romosozumab on Bone Density in Women With Anorexia Nervosa
Not yet reported Karen Klahr Miller, MD 30 participants Est. completion 2025-11-17 1 siteObstructive sleep apnea Other conditions: Bone Density, Low, Bone Loss, Eating DisordersView official trial listing → -
Status unknown NCT NCT04899713
NEOZOL_Follow-up Study
Hospices Civils de Lyon 50 participants Est. completion 2021-12-31 11 sitesOther conditions: Locally Advanced Breast CancerView official trial listing → -
Completed NCT NCT05025293
Zoledronate Early to Hip Fracture Patients - Safe and Effective?
Not yet reported Lene Bergendal Solberg 228 participants Est. completion 2026-06-11 1 siteOther conditions: Hip Fractures, OsteoporosisView official trial listing → -
Active, not recruiting NCT NCT05053750
TAME: A Pilot Study of Weekly Paclitaxel, Bevacizumab, and Tumor Associated Macrophage Targeted Therapy (Zoledronic Acid) in Women With Recurrent, Platinum-resistant, Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Not yet reported M.D. Anderson Cancer Center 14 participants Est. completion 2027-02-02 1 siteOther conditions: Epithelial Ovarian, Fallopian Tube, Primary Peritoneal CancerView official trial listing → -
Active, not recruiting NCT NCT05058976
Romosozumab Use to Build Skeletal Integrity
Not yet reported Susan L. Greenspan 184 participants Est. completion 2027-03-31 1 siteOther conditions: Osteoporosis, Osteoporosis, Postmenopausal, Osteoporosis FractureView official trial listing → -
Completed NCT NCT05080790
Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With Leiomyosarcoma
Not yet reported Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 7 participants Est. completion 2025-01-20 2 sitesObstructive sleep apneaView official trial listing → -
Active, not recruiting NCT NCT05091086
The Optimal Long Term Treatment Strategy of Anti-resorptive Medications
Not yet reported National Taiwan University Hospital 60 participants Est. completion 2030-12-31 1 siteOther conditions: Osteoporosis, Bone Mineral DensityView official trial listing → -
Completed NCT NCT05091099
The Optimal Sequential Therapy After Long Term Denosumab Treatment
Not yet reported National Taiwan University Hospital 44 participants Est. completion 2025-11-14 1 siteOther conditions: OsteoporosisView official trial listing → -
Status unknown NCT NCT05106517
Denosumab vs Zoledronic Acid and Osteoporotic Compression Fracture
Not yet reported, Not yet reported Shenzhen People's Hospital 122 participants Est. completion 2023-03-11 1 siteOther conditions: Denosumab vs ZoledronateView official trial listing → -
Status unknown NCT NCT05164952
Delayed Versus Immediate Use Of Zoledronic Acid For Postmenopausal Patients With Early Breast Cancer Who Are Using Adjuvant Letrozole
Not yet reported Assiut University 50 participants Est. completion 2023-09-30 1 siteOther conditions: Use of Zoledronic Acid in Breast CancerView official trial listing → -
Terminated NCT NCT05204836
Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention Following an Acute Knee Injury
Not yet reported University of Calgary 4 participants Est. completion 2025-07-03 1 siteOther conditions: Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries, Osteo Arthritis KneeView official trial listing → -
Completed NCT NCT05328154
MAGnesium Effect With ANtiosteoporotic Drugs
Not yet reported University Hospital, Clermont-Ferrand 45 participants Est. completion 2024-12-19 1 siteOther conditions: Osteoporosis, PostmenopausalView official trial listing → -
Completed NCT NCT05361408
A Clinical Trial to Evaluate Efficacy of Once or Twice ZOledronic Acid After Different Duration of denOsumMab Administration in Postmenopausal Women With Osteoporosis (ZOOM Study)
Not yet reported Yonsei University 114 participants Est. completion 2024-02-13 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT05366621
Post-fracture Medication and Mortality
National Cheng-Kung University Hospital 216155 participants Est. completion 2021-10-31 1 siteOther conditions: Osteoporosis, Osteoporosis Fracture, Drug Therapy, Mortality, Adherence, MedicationView official trial listing → -
Status unknown NCT NCT05405894
Efficacy of Zoledronic Acid to Prevent Bone Loss Following Denosumab Discontinuation
University of Calgary 20 participants Est. completion 2025-07-01 1 siteOther conditions: Osteoporosis, Osteoporosis, Postmenopausal, Osteopenia, Bone LossView official trial listing → -
Not yet recruiting NCT NCT05480189
Effect of Zoledronic Acid Treatment on Bone-related Events in Breast Cancer Patients With Bone Metastases: a Prospective, Multicenter, Real-world Study
Zhejiang Cancer Hospital 1000 participants Est. completion 2027-03-31Other conditions: Histologically Confirmed Breast Cancer ,Diagnosis of Bone MetastasisView official trial listing → -
Active, not recruiting NCT NCT05575167
Single or Repeat Zoledronate Versus Alendronate Following Denosumab (EUROpean Denosumab Effects Consolidation Study)
424 General Military Hospital 122 participants Est. completion 2027-11 9 sitesOther conditions: Osteoporosis, PostmenopausalView official trial listing → -
Completed NCT NCT05598606
Denosumab vs Zoledronate After Vertebroplasty
Not yet reported Shenzhen People's Hospital 75 participants Est. completion 2023-01-14 1 siteOther conditions: Denosumab Allergy, Zoledronic Acid AllergyView official trial listing → -
Completed NCT NCT05614778
Study to Investigate the Efficacy and Safety After Administration of Daewoong Zoledronic Acid for the Purpose of Treatment or Prevention of Osteoporosis
Daewoong Pharmaceutical Co. LTD. 2881 participants Est. completion 2024-05-31 1 siteOther conditions: OsteoporosisView official trial listing → -
Status unknown NCT NCT05638399
Denosumab vs Zoledronate After Lumbar Fusion
Not yet reported Shenzhen People's Hospital 100 participants Est. completion 2023-02-28 1 siteOther conditions: Osteopenia, Lumbar SpondylolisthesisView official trial listing → -
Active, not recruiting NCT NCT05655013
Treatment With Zoledronate Subsequent to Denosumab in Osteoporosis 2 (ZOLARMAB2)
Not yet reported Aarhus University Hospital 200 participants Est. completion 2027-02-01 1 siteOther conditions: Osteoporosis, PostmenopausalView official trial listing → -
Active, not recruiting NCT NCT05666310
Muscle Impact of Treating Osteoporosis
Not yet reported Nami Safai Haeri 20 participants Est. completion 2026-09-05 1 siteOther conditions: Sarcopenia, OsteoporosisView official trial listing → -
Status unknown NCT NCT05743179
The Effect of Zoledronate on the Prevention of Pneumonia in Hip Fracture Patients
Not yet reported The University of Hong Kong 2692 participants Est. completion 2025-06 5 sitesOther conditions: Hip Fractures, PneumoniaView official trial listing → -
Status unknown NCT NCT05866172
HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC
Not yet reported Sun Yat-sen University 264 participants Est. completion 2025-06-01 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT06023420
Efficacy of a Herbal Formula for Bone Metastases
Not yet reported, Not yet reported Chinese University of Hong Kong 36 participants Est. completion 2025-01-01Other conditions: Bone MetastasesView official trial listing → -
Status unknown NCT NCT06051344
Effect of Zoledronic Acid in Primary Knee Osteoarthritis
Not yet reported Toufiqe-E-Ealahi 92 participants Est. completion 2023-12-31 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT06135298
FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZA
Not yet reported Aksaray University 20 participants Est. completion 2026-01-15 1 siteOther conditions: Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur, Hip Fractures, Bone Density, LowView official trial listing → -
Not yet recruiting NCT NCT06221072
A Study to Assess the Prevention of Bone-related Events in Patients With Bone Metastases From Malignant Solid Tumors Treated With JMT103 Compared to Zoledronic Acid
Not yet reported Shanghai JMT-Bio Inc. 1360 participants Est. completion 2028-05-31Other conditions: Imaging Examination Shows at Least One Site With Bone Metastases From Soild TumorsView official trial listing → -
Completed NCT NCT06621069
The Effect of Long-term Use of Bisphosphonates on Femur Morphology
Second Affiliated Hospital, Zhejiang University, School of Medicine 140 participants Est. completion 2024-08-01 1 siteOther conditions: Osteoporosis, Knee OsteoarthristisView official trial listing → -
Enrolling by invitation NCT NCT06811363
Contribution of Bone to Urine Citrate
University of Texas Southwestern Medical Center 25 participants Est. completion 2027-03 1 siteOther conditions: OsteoporosisView official trial listing → -
Active, not recruiting NCT NCT06876636
Zoledronic Acid Combined With EC-T for Triple-Negative Breast Cancer
Not yet reported Xijing Hospital 99 participants Est. completion 2025-12 1 siteOther conditions: Breast Cancer MetastaticView official trial listing → -
Not yet recruiting NCT NCT07056478
RANKL Inhibition to Combat Sarcopenia in Hip Fracture Patients
Not yet reported Prince of Wales Hospital, Shatin, Hong Kong 130 participants Est. completion 2030-01-01 1 siteOther conditions: Sarcopenia in ElderlyView official trial listing → -
Not yet recruiting NCT NCT07204496
A Clinical Study on the Safety, Tolerance, and Preliminary Efficacy of γδ-T Cell Injection in the Treatment of Advanced Bladder Cancer
Shanghai 10th People's Hospital 20 participants Est. completion 2026-12-31Other conditions: Advanced Bladder CancerView official trial listing → -
Completed NCT NCT07546058
Effect of Local Subperiosteal Zoledronic Acid Injection on the Survival of Orthodontic Miniscrews
Not yet reported Latakia University 68 participants Est. completion 2026-02-03 1 siteOther conditions: Orthodontic Appliance ComplicationView official trial listing → -
Not yet recruiting NCT NCT07668583
EFFICACY AND SAFETY OF ZOLEDRONATE VERSUS PLACEBO ON PAIN AT WEEK 12 IN PEDIATRIC PATIENTS WITH CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS
Not yet reported Assistance Publique - Hôpitaux de Paris 30 participants Est. completion 2029-12-31 1 siteOther conditions: Osteomyelitis ChronicView official trial listing → -
Not yet recruiting NCT NCT07687225
Surgery vs. No Surgery for Primary Tumor in De Novo Stage IV Breast Cancer With Solitary Bone Metastases
Not yet reported West China Hospital 216 participants Est. completion 2036-12-31Other conditions: Breast Cancer, Stage IV Breast Cancer, Bone MetastasesView official trial listing → -
Not yet recruiting NCT NCT07741136
Pharmacokinetics of Zoledronic Acid in Patients on Dialysis
Not yet reported University of Campinas, Brazil 24 participants Est. completion 2028-08-15 1 siteChronic kidney disease Other conditions: Osteoporosis, DialysisView official trial listing → -
Not yet recruiting NCT NCT07753317
Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DM
Not yet reported Cairo University 30 participants Est. completion 2027-03-01Other conditions: Controlled Type 2 Diabetic Patients With PeriodontitisView official trial listing → -
Not yet recruiting NCT NCT07772609
Sequential Treatment With Romosozumab Followed by Denosumab vs. Zoledronic Acid for Gains in HIP BMD
Not yet reported Sahlgrenska University Hospital 216 participants Est. completion 2031-12-31 9 sitesOther conditions: Osteoporosis in Post-menopausal WomenView official trial listing → -
Completed NCT NCT07823751
The Role of Bisphosphonate and Simvastatin Combination on Therapeutic Response in Breast Cancer With Bone Metastasis Via Dicckopf-1 Pathway
Not yet reported Universitas Indonesia 35 participants Est. completion 2026-06-20 1 siteOther conditions: Breast Cancer With Bone MetastasisView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Zoledronic Acid /Bag Infusion, Zoledronic Acid 5Mg/Bag 100Ml Infusion, Reclast
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
