GLP-1 Market
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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Zoledronic Acid /Bag Infusion

Company
Chrissy Kistler
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
28 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

28 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Sep 24, 2026

Find a Clinical Trial Near Me

See recruiting studies for Zoledronic Acid /Bag Infusion and check eligibility with the study team.

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Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

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Trial details
  • Recruiting NCT NCT02508038

    Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

    Not yet reported University of Wisconsin, Madison 22 participants Est. completion 2027-12 1 site
    Obstructive sleep apnea Other conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Myelodysplastic Syndrome, Myeloproliferative Syndrome, Ewing Sarcoma, Primitive Neuroectodermal Tumor, Neuroblastoma
    View official trial listing →
  • Recruiting NCT NCT03295981

    Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of Bone

    Not yet reported St. Louis University 120 participants Est. completion 2028-01 16 sites
    Other conditions: Giant Cell Tumor of Bone
    View official trial listing →
  • Recruiting NCT NCT03958565

    Response of Bony Metastasis to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancers With Actionable Driver Mutations.

    University of Colorado, Denver 100 participants Est. completion 2028-04-28 2 sites
    Other conditions: Carcinoma, Non-Small-Cell Lung
    View official trial listing →
  • Recruiting NCT NCT04608630

    Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults

    Not yet reported Australian and New Zealand Intensive Care Research Centre 450 participants Est. completion 2027-02-28 22 sites
    Other conditions: Critical Illness, Osteoporosis
    View official trial listing →
  • Recruiting NCT NCT04725422

    CHronic Nonbacterial Osteomyelitis International Registry

    Seattle Children's Hospital 2000 participants Est. completion 2050-08 1 site
    Other conditions: Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal Osteomyelitis
    View official trial listing →
  • Recruiting NCT NCT05400603

    Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma

    Not yet reported Emory University 24 participants Est. completion 2026-12 1 site
    Obstructive sleep apnea Other conditions: Neuroblastoma, Refractory Neuroblastoma, Relapsed Neuroblastoma
    View official trial listing →
  • Recruiting NCT NCT05493267

    A Exploratory Study of Vγ2Vδ2 T Lymphocyte-based Immunotherapy for MDR-TB

    Not yet reported Shanghai Pulmonary Hospital, Shanghai, China 30 participants Est. completion 2027-08-03 2 sites
    Other conditions: MDR-TB, Immunotherapy
    View official trial listing →
  • Recruiting NCT NCT05595603

    Zoledronic Acid-loaded Bone Cement as a Local Adjuvant Therapy for Giant Cell Bone Tumor After Intralesional Curettage

    Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 153 participants Est. completion 2026-12-01 1 site
    Other conditions: Giant Cell Tumor of Bone
    View official trial listing →
  • Recruiting NCT NCT05677152

    Influence of an Anti-osteoporotic Drug on Healing After Surgical Repair of Chronic Rotator Cuff Lesions of the Shoulder

    Not yet reported AUVA Traumazentrum Vienna Site UKH Meidling 80 participants Est. completion 2030-12 1 site
    Other conditions: Orthopedics, Traumatology
    View official trial listing →
  • Recruiting NCT NCT05904353

    A Study to Improve the Collaboration Between Primary and Secondary Health Care on the Treatment of Osteoporosis After a Hip Fracture.

    Not yet reported University Hospital, Akershus 200 participants Est. completion 2026-12 1 site
    Other conditions: Hip Fractures, Osteoporosis, Zoledronic Acid, Ambulant Nurse, Case Manager
    View official trial listing →
  • Recruiting NCT NCT05906056

    Continuous Passive Motion Versus Heterotopic Ossification

    Not yet reported University of Ioannina 20 participants Est. completion 2027-03-25 1 site
    Cardiovascular disease Other conditions: Traumatic Brain Injury, Spinal Cord Injuries
    View official trial listing →
  • Recruiting NCT NCT06059222

    The Optimised Use of Romozosumab Study

    Not yet reported University of Aarhus 270 participants Est. completion 2032-08-31 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Recruiting NCT NCT06118905

    Preserving Geriatric Muscle With an Osteoporosis Medication

    Not yet reported Chrissy Kistler 155 participants Est. completion 2029-03-31 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Recruiting NCT NCT06164795

    Sequential Therapies After Osteoanabolic Treatment

    424 General Military Hospital 150 participants Est. completion 2027-12 8 sites
    Other conditions: Osteoporosis, Postmenopausal
    View official trial listing →
  • Recruiting NCT NCT06374459

    Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone Metastasis

    Not yet reported, Not yet reported Washington University School of Medicine 152 participants Est. completion 2032-05-31 3 sites
    Other conditions: Hormone Receptor Positive HER-2 Negative Metastatic Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT06513624

    ETC-159 In Combination With Pembrolizumab In Advanced MSS/pMMR Ovarian Cancers

    Not yet reported National University Hospital, Singapore 16 participants Est. completion 2027-06-30 2 sites
    Other conditions: With MSS/pMMR Advanced, Platinum-resistant Ovarian Cancer
    View official trial listing →
  • Recruiting NCT NCT06533865

    Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea

    Not yet reported Massachusetts General Hospital 114 participants Est. completion 2029-04 2 sites
    Other conditions: FHA (Functional Hypothalamic Amenorrhea)
    View official trial listing →
  • Recruiting NCT NCT06625190

    Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

    Not yet reported, Not yet reported University of Florida 27 participants Est. completion 2030-02 1 site
    Obstructive sleep apnea Other conditions: Neuroblastoma, Synovial Sarcoma, Peripheral Nerve Sheath Tumors, Clear Cell Sarcoma, Alveolar Soft Part Sarcoma, Desmoplastic Small Round Cell Tumor, Chordoma, Rhabdoid Tumor, Epithelioid Sarcoma, Myoepithelial Tumor, Ewing Sarcoma, Wilms Tumor
    View official trial listing →
  • Recruiting NCT NCT06643780

    RANK-ligand Inhibition to Combat Sarcopenia With Underlying Osteoporosis

    Not yet reported Prince of Wales Hospital, Shatin, Hong Kong 120 participants Est. completion 2027-10 1 site
    Other conditions: Sarcopenia in Elderly
    View official trial listing →
  • Recruiting NCT NCT06759064

    Intraperitoneal Immune Checkpoint Inhibitors and Zoledronic Acids for Gastric Cancer Malignant Ascites

    Not yet reported, Not yet reported Qilu Hospital of Shandong University 24 participants Est. completion 2026-09-01 1 site
    Other conditions: Cancer of Stomach, Adenocarcinoma, Ascites, Malignant
    View official trial listing →
  • Recruiting NCT NCT06762730

    Zoledronic Acid for the Prevention of TDF-sparing ART-induced Bone Mass Density Loss in Treatment-naive HIV Positive Individuals

    Not yet reported Hadassah Medical Organization 110 participants Est. completion 2032-12-01 3 sites
    Other conditions: HIV Infected Individuals, Osteopenia
    View official trial listing →
  • Recruiting NCT NCT06767150

    StrAtegies For Zoledronic Acid Post-dEnosumab Discontinuation in Postmenopausal oSTeoporosis

    Not yet reported University Hospital, Toulouse 200 participants Est. completion 2030-10 17 sites
    Other conditions: Postmenopausal Osteoporosis
    View official trial listing →
  • Recruiting NCT NCT06859580

    Bisphosphonate Prior to Parathyroidectomy in Primary Hyperparathyroidism

    Not yet reported University of Aarhus 140 participants Est. completion 2028-02-01 1 site
    Other conditions: Primary Hyperparathyroidism
    View official trial listing →
  • Recruiting NCT NCT07043608

    Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases

    Not yet reported Kelly Fitzgerald, MD 20 participants Est. completion 2030-04-30 1 site
    Other conditions: Clear Cell Renal Cell Cancer (ccRCC), Clear Cell Renal Carcinoma, Clear Cell Renal Cell Carcinoma Metastatic, Clear Cell Renal Cancer, Bone Metastases of a Malignant Tumor, Clear Cell Renal Cell Carcinoma, Bone, Metastatic Cancer, Metastatic Cancer, Metastatic Renal Cell Carcinoma, Metastases to Bone
    View official trial listing →
  • Recruiting NCT NCT07281586

    Step-down Therapy After Long-term Osteoporosis Treatment

    Not yet reported National Taiwan University Hospital 44 participants Est. completion 2028-12-31 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Recruiting NCT NCT07375290

    Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant Survivors

    Not yet reported Children's Hospital Medical Center, Cincinnati 20 participants Est. completion 2028-11 1 site
    Other conditions: Hematopoietic Stem Cell Transplantation
    View official trial listing →
  • Recruiting NCT NCT07406685

    The Comparison of Ibandronate and Zoledronic Acid After Denosumab Discontinuation

    Not yet reported National Taiwan University Hospital 52 participants Est. completion 2030-10-31 1 site
    Other conditions: Postmenopausal Osteoporosis, Postmenopausal Osteopenia, Primary Osteoporosis, Osteoporosis
    View official trial listing →
  • Recruiting NCT NCT07471516

    Zoledronic Acid Treatment in Patients With Congenital Dyserythropoietic Anemia

    Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 2 participants Est. completion 2027-08-12 1 site
    Other conditions: Congenital Dyserythropoietic Anemia (CDA)
    View official trial listing →
  • Completed NCT NCT00003884

    Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone

    Not yet reported Novartis 600 participants Est. completion 2001-01 55 sites
    Other conditions: Hypercalcemia of Malignancy, Lung Cancer, Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00004928

    Calcitriol and Zoledronate in Treating Patients With Progressive Prostate Cancer

    Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2004-10 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00005073

    Zoledronate Plus Standard Therapy Compared With Placebo Plus Standard Therapy to Prevent Bone Metastases in Patients With Recurrent Prostate Cancer That Has No Symptoms

    Not yet reported Novartis Pharmaceuticals 544 participants Est. completion 2003-03 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00022087

    Zoledronate, Calcium, and Vitamin D in Preventing Bone Loss in Women Receiving Adjuvant Chemotherapy for Breast Cancer

    Not yet reported Alliance for Clinical Trials in Oncology 439 participants Est. completion 2009-02 107 sites
    Other conditions: Breast Cancer, Osteoporosis
    View official trial listing →
  • Completed NCT NCT00029224

    Treatment With Zoledronic Acid in Patients With Breast Cancer, Multiple Myeloma, and Prostate Cancer With Cancer Related Bone Lesions

    Not yet reported Novartis 500 participants Est. completion 2002-11 7 sites
    Other conditions: Breast Cancer, Multiple Myeloma, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00033332

    Dexamethasone With or Without Thalidomide in Treating Patients With Newly Diagnosed Multiple Myeloma

    Not yet reported National Cancer Institute (NCI) Est. completion 2006-06 78 sites
    Other conditions: Multiple Myeloma and Plasma Cell Neoplasm
    View official trial listing →
  • Completed NCT NCT00035997

    Open-label Trial on the Effect of I.V. Zoledronic Acid 4 mg on Bone Density in Hormone Sensitive Prostate Cancer Patients With Bone Metastasis

    Not yet reported Novartis Pharmaceuticals 261 participants Est. completion 2004-01 56 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00039104

    Zoledronate and BMS-275291 in Treating Patients With Prostate Cancer

    Not yet reported National Cancer Institute (NCI) 50 participants 1 site
    Other conditions: Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage IV Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00046254

    Evaluating the Ability of Zoledronic Acid to Reduce the Rate of Subsequent Osteoporotic Fractures After a Hip Fracture

    Not yet reported Novartis Pharmaceuticals 2127 participants Est. completion 2007-02 28 sites
    Other conditions: Osteoporosis, Hip Fracture
    View official trial listing →
  • Completed NCT NCT00049452

    Zoledronate in Preventing Bone Loss in Premenopausal Women Receiving Chemotherapy After Surgery For Early Stage Breast Cancer

    Not yet reported Herbert Irving Comprehensive Cancer Center 120 participants Est. completion 2008-08 3 sites
    Other conditions: Breast Cancer, Osteoporosis
    View official trial listing →
  • Completed NCT NCT00049829

    HORIZON-PFT: Pivotal Fracture Trial

    Not yet reported Novartis Pharmaceuticals 7700 participants 60 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00050011

    Zoledronic Acid - Letrozole Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women With Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy

    Not yet reported Novartis Pharmaceuticals 602 participants Est. completion 2009-01 44 sites
    Other conditions: Breast Neoplasms, Osteoporosis
    View official trial listing →
  • Completed NCT NCT00051636

    Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period

    Not yet reported Novartis Pharmaceuticals 172 participants Est. completion 2011-04 34 sites
    Other conditions: Paget's Disease of Bone
    View official trial listing →
  • Completed NCT NCT00051779

    An Investigational Drug (CAL) Versus Zoledronic Acid (Zometa®) in Patients With Breast Cancer

    Not yet reported Chugai Pharma USA 38 sites
    Other conditions: Breast Neoplasms, Breast Cancer, Metastasis
    View official trial listing →
  • Terminated NCT NCT00058188

    Zolendronate for the Prevention of Bone Loss in Men w/ Prostate CA on Long-Term Androgen Deprivation

    Not yet reported Northwestern University 53 participants Est. completion 2008-11 3 sites
    Other conditions: Osteoporosis, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00060138

    Monoclonal Antibody Compared With Zoledronate in Treating Women With Breast Cancer and Bone Metastases

    Not yet reported, Not yet reported Chugai Pharmaceutical 1 site
    Other conditions: Breast Cancer, Hypercalcemia of Malignancy, Metastatic Cancer, Pain
    View official trial listing →
  • Completed NCT NCT00063479

    Bisphosphonate Treatment of Osteogenesis Imperfecta

    Not yet reported Novartis Pharmaceuticals 158 participants Est. completion 2007-05 10 sites
    Other conditions: Osteogenesis Imperfecta
    View official trial listing →
  • Completed NCT NCT00063609

    The Effect of Zoledronic Acid on Bone Loss in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy

    Not yet reported Novartis Pharmaceuticals 200 participants Est. completion 2005-04 44 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT00072020

    Chemotherapy and/or Hormone Therapy With or Without Zoledronate in Treating Women With Stage II or Stage III Breast Cancer

    Not yet reported University of Sheffield
    Other conditions: Breast Cancer, Metastatic Cancer
    View official trial listing →
  • Completed NCT NCT00072930

    MEDI-522 in the Treatment of Patients With Metastatic Androgen-Independent Prostate Cancer

    Not yet reported MedImmune LLC 150 participants Est. completion 2007-06 57 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00079001

    Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases

    Not yet reported Alliance for Clinical Trials in Oncology 645 participants Est. completion 2014-10 241 sites
    Other conditions: Metastatic Cancer, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00081159

    Hormone Ablation Therapy, Doxorubicin, and Zoledronate With or Without Strontium 89 in Treating Patients With Androgen-Dependent Prostate Cancer and Bone Metastases

    Not yet reported M.D. Anderson Cancer Center 80 participants Est. completion 2014-09 4 sites
    Other conditions: Metastatic Cancer, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00083382

    Combination Bisphosphonate and Anti-Angiogenesis Therapy With Pamidronate and Thalidomide

    Not yet reported University of Arkansas 83 participants Est. completion 2014-05 1 site
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00086268

    Non-small Cell Lung Cancer Study US75 (Z-PACT)

    Not yet reported Novartis Pharmaceuticals 250 participants Est. completion 2007-10 80 sites
    Other conditions: Non Small Cell Lung Carcinoma
    View official trial listing →
  • Completed NCT NCT00087659

    A Prostate Cancer Study in Men Undergoing Androgen Deprivation Therapy

    Not yet reported Novartis Pharmaceuticals Est. completion 2007-05 16 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00091832

    Denosumab (AMG 162) in Bisphosphonate Naive Metastatic Breast Cancer

    Not yet reported Amgen 255 participants Est. completion 2006-10
    Other conditions: Breast Cancer, Metastases, Bone Metastases in Subjects With Advanced Breast Cancer
    View official trial listing →
  • Completed NCT NCT00097812

    Switching Osteoporosis Patients Currently on Oral Bisphosphonate to Zoledronic Acid

    Not yet reported Novartis Pharmaceuticals 220 participants Est. completion 2005-12 13 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00097825

    Efficacy and Safety of Zoledronic Acid for the Treatment of Osteoporosis in Men

    Not yet reported Novartis Pharmaceuticals 288 participants Est. completion 2007-08 26 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Terminated NCT NCT00099177

    A Study to Assess the Efficacy of Intravenous/Oral Bondronat (Ibandronate) in Patients With Metastatic Bone Disease Experiencing Moderate to Severe Pain

    Not yet reported Hoffmann-La Roche 96 participants Est. completion 2007-12 41 sites
    Other conditions: Pain, Bone Neoplasm, Neoplasm Metastasis
    View official trial listing →
  • Terminated NCT NCT00099203

    A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease

    Not yet reported Hoffmann-La Roche 163 participants Est. completion 2007-12 72 sites
    Other conditions: Pain, Bone Neoplasm, Neoplasm Metastasis
    View official trial listing →
  • Completed NCT NCT00099541

    Non-small Cell Lung Cancer Registry

    Not yet reported Novartis Pharmaceuticals 300 participants Est. completion 2007-11 101 sites
    Other conditions: Non-Small-Cell Lung Cancer, Pleural Effusion, Malignant
    View official trial listing →
  • Completed NCT NCT00100555

    A Study of the Clinical Safety, Tolerability, and Efficacy of Zoledronic Acid Compared to an Oral Bisphosphonate

    Not yet reported Novartis Pharmaceuticals 120 participants Est. completion 2005-06 18 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00100620

    Efficacy and Safety of Zoledronic Acid in the Prevention and Treatment of Corticosteroid Induced Osteoporosis

    Not yet reported Novartis Pharmaceuticals 802 participants Est. completion 2007-04 6 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT00102908

    Bisphosphonate Therapy for HIV-Infected Adults With Decreased Bone Mineral Density

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 30 participants Est. completion 2009-12 1 site
    Other conditions: HIV Infections, Osteopenia, Osteoporosis
    View official trial listing →
  • Completed NCT NCT00103740

    Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period

    Not yet reported Novartis Pharmaceuticals 185 participants Est. completion 2011-04 41 sites
    Other conditions: Paget's Disease of Bone
    View official trial listing →
  • Completed NCT NCT00104104

    A Multiple Myeloma Trial in Patients With Bone Metastases

    Not yet reported Novartis Pharmaceuticals 179 participants Est. completion 2007-10 68 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00104650

    Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates

    Not yet reported Amgen 111 participants Est. completion 2010-03
    Other conditions: Bone Metastases in Men With Hormone-Refractory Prostate Cancer, Bone Metastases in Subjects With Advanced Breast Cancer, Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00107263

    Zoledronate in Preventing Bone Loss in Postmenopausal Women Who Are Receiving Letrozole for Stage I, Stage II, or Stage IIIA Breast Cancer

    Not yet reported Alliance for Clinical Trials in Oncology 558 participants Est. completion 2012-08
    Other conditions: Breast Cancer, Osteoporosis
    View official trial listing →
  • Completed NCT NCT00114270

    Letrozole With or Without Zoledronate in Treating Healthy Postmenopausal Women With High Breast Density

    Not yet reported University of Virginia Est. completion 2007-06 1 site
    Other conditions: Breast Cancer, Osteoporosis
    View official trial listing →
  • Completed NCT NCT00114556

    The Effect of Zoledronic Acid on Bone Density in Liver Transplant Patients

    Not yet reported Royal Prince Alfred Hospital, Sydney, Australia 100 participants Est. completion 2004-08 1 site
    Other conditions: Osteoporosis, Liver Transplantation, Fractures
    View official trial listing →
  • Completed NCT NCT00120133

    Atorvastatin (Lipitor) to Prevent Bone Pain

    Not yet reported Children's Mercy Hospital Kansas City 12 participants Est. completion 2007-12 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00126386

    Zometa for the Management of Tumor-induced Hypercalcemia and Malignant Bone Pain in the Community

    Not yet reported Alberta Health services 11 participants Est. completion 2006-09 1 site
    Other conditions: Cancer, Hypercalcemia, Pain
    View official trial listing →
  • Completed NCT NCT00127205

    S0307 Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer.

    Not yet reported SWOG Cancer Research Network 6097 participants Est. completion 2021-03-29
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT00130494

    Zoledronic Acid Administration to Metastatic Breast Cancer Patients With Non-symptomatic Bone Lesions

    Not yet reported Spanish Breast Cancer Research Group 97 participants Est. completion 2007-10-22 1 site
    Other conditions: Breast Cancer, Neoplasm Metastasis
    View official trial listing →
  • Completed NCT NCT00131118

    Zoledronic Acid in Children (1 -17 Years) With Severe Osteogenesis Imperfecta

    Not yet reported Novartis Pharmaceuticals 127 participants Est. completion 2007-05 10 sites
    Other conditions: Osteogenesis Imperfecta
    View official trial listing →
  • Completed NCT NCT00132808

    Zoledronic Acid in the Prevention of Bone Loss in Postmenopausal Women With Osteopenia, 45 Years of Age and Older

    Not yet reported Novartis Pharmaceuticals 581 participants Est. completion 2008-02 1 site
    Other conditions: Osteopenia
    View official trial listing →
  • Completed NCT NCT00145275

    To Assess the Efficacy of Over-the-counter Analgesics in the Prevention/Treatment of Transient Post-dose Symptoms Following Zoledronate Infusion in Post-menopausal Women

    Not yet reported Novartis 455 participants Est. completion 2005-10 10 sites
    Other conditions: Osteopenia
    View official trial listing →
  • Completed NCT NCT00145327

    Double-blind Extension of HORIZON Pivotal Fracture Trial (Zoledronic Acid in the Treatment of Postmenopausal Osteoporosis)

    Not yet reported Novartis 2456 participants Est. completion 2009-11 31 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00151073

    Estramustine, Docetaxel and Zoledronate Treatment in Hormone-Refractory Adenocarcinoma of the Prostate

    Not yet reported University of Michigan Rogel Cancer Center 28 participants Est. completion 2007-09 1 site
    Other conditions: Hormone-Refractory Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00164008

    Comparison of Pamidronate With Zoledronic Acid for Transplant Related Bone Loss Prevention

    Not yet reported Bayside Health 56 participants Est. completion 2005-12
    Other conditions: Osteopenia, Complications of Heart-lung Transplant, Other Complications of Lung Transplant
    View official trial listing →
  • Completed NCT NCT00171314

    The Use of Zoledronic Acid to Prevent Cancer-treatment Bone Loss in Post-menopausal Women Receiving Adjuvant Letrozole for Breast Cancer

    Not yet reported Novartis Pharmaceuticals 527 participants 49 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00171340

    Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer.

    Not yet reported Novartis Pharmaceuticals 1065 participants Est. completion 2010-02 106 sites
    Other conditions: Bone Loss, Breast Cancer
    View official trial listing →
  • Completed NCT NCT00171639

    The Use of Zoledronic Acid in Men on Androgen Deprivation Therapy for Prostate Cancer With Preexisting Osteoporosis

    Not yet reported Novartis Pharmaceuticals 28 participants Est. completion 2007-03 7 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00171925

    Therapy With Zoledronic Acid in Patients With Multiple Myeloma Stage I

    Not yet reported Novartis Pharmaceuticals 143 participants Est. completion 2008-11 1 site
    Other conditions: Multiple Myeloma Stage I
    View official trial listing →
  • Completed NCT NCT00171964

    Efficacy and Tolerability of Zoledronic Acid With Radiotherapy in Pts With Advanced Osteolytic Bone Lesions

    Not yet reported Novartis Pharmaceuticals 75 participants Est. completion 2008-12 1 site
    Other conditions: Pain, Neoplasm Metastasis, Cancer
    View official trial listing →
  • Completed NCT NCT00172003

    Effect of Zoledronic Acid in Patients With Renal Cell Cancer and Bone Metastasis

    Not yet reported Novartis Pharmaceuticals 50 participants Est. completion 2009-07 1 site
    Other conditions: Renal Cell Cancer, Neoplasm Metastasis
    View official trial listing →
  • Completed NCT NCT00172016

    A Study to Evaluate the Efficacy and Tolerability of Zoledronic Acid in Patients With Metastatic Prostate Cancer Who Can be Treated With a Group of Medications Known as Bisphosphonates

    Not yet reported Novartis Pharmaceuticals 43 participants
    Other conditions: Prostate Cancer With at Least One Bone Lesion in Patients Receiving Hormonal Therapy and Treatment With Bisphosphonates is Indicated
    View official trial listing →
  • Completed NCT NCT00172029

    Study Comparing Full-dose Radiotherapy Versus Reduced Dose in the Management of Bone Metastasis in Patients With Breast Cancer Receiving Zoledronic Acid

    Not yet reported Novartis 116 participants 7 sites
    Other conditions: Breast Cancer With Metastatic Bone Disease
    View official trial listing →
  • Completed NCT NCT00172042

    A Study to Evaluate the Safety and Efficacy of Zoledronic Acid in the Prevention or Delaying of Bone Metastasis in Patients With Stage IIIA and IIIB Non-small Cell Lung Cancer (NSCLC)

    Not yet reported Novartis Pharmaceuticals 437 participants Est. completion 2010-06 69 sites
    Other conditions: Non-Small-Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT00172055

    Study to Assess Efficacy and Safety of Zoledronic Acid and the Value of Markers of Bone Resorption in the Prediction of Bone Metastases and Cancer Treatment-induced Bone Loss (CTIBL) in Patients With Prostate Cancer on Hormone Therapy

    Not yet reported Novartis Pharmaceuticals 218 participants Est. completion 2009-07 19 sites
    Other conditions: Cancer Prostate
    View official trial listing →
  • Terminated NCT NCT00172068

    Zoledronic Acid in the Treatment of Breast Cancer With Minimal Residual Disease in the Bone Marrow

    Not yet reported Novartis Pharmaceuticals 96 participants 4 sites
    Other conditions: Primary Breast Cancer
    View official trial listing →
  • Completed NCT NCT00181558

    Atrasentan and Zometa for Men With Prostate Cancer Metastatic to Bone

    Not yet reported Massachusetts General Hospital 44 participants Est. completion 2006-12 2 sites
    Other conditions: Prostate Cancer, Adenocarcinoma of the Prostate
    View official trial listing →
  • Completed NCT NCT00181584

    Zoledronic Acid to Prevent Bone Loss During Androgen Deprivation Therapy for Prostate Cancer

    Not yet reported Massachusetts General Hospital 60 participants 2 sites
    Other conditions: Bone Loss, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00193856

    RADAR Trial - Randomised Androgen Deprivation and Radiotherapy

    Not yet reported Trans Tasman Radiation Oncology Group 1071 participants Est. completion 2017-08 24 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00202059

    Effects of Zometa and Physical Activity on Bone Density in Women Receiving Chemotherapy for Breast Cancer

    Not yet reported HealthPartners Institute 72 participants Est. completion 2007-09 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00206388

    Zoledronic Acid (ZOMETA) With Cyclophosphamide With Neuroblastoma and Cortical Bone Involvement

    Not yet reported Baylor College of Medicine 21 participants Est. completion 2013-05 8 sites
    Other conditions: NEUROBLASTOMA
    View official trial listing →
  • Terminated NCT NCT00210119

    Imatinib Mesylate and Zoledronic Acid in Patients With Chronic Myeloid Leukaemia in Cytogenetic Response Without Molecular Response

    Not yet reported Institut Bergonié 19 participants Est. completion 2009-03 7 sites
    Other conditions: Myeloid Leukemia, Chronic
    View official trial listing →
  • Completed NCT NCT00213980

    Bone Mineral Density Effects of Zoledronate in Postmenopausal Women With Breast Cancer

    Not yet reported University of Wisconsin, Madison 68 participants Est. completion 2008-04 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT00215943

    Phase III Randomized Trial of Thalidomide/Dexamethasone Versus Vincristine+Adriamycin+Dexamethasone (VAD)

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 90 participants Est. completion 2012-08 5 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Terminated NCT NCT00216151

    Zoledronic Acid in the Management of Patients With Asymptomatic/Early Stage Multiple Myeloma

    Not yet reported Hoosier Cancer Research Network 3 participants Est. completion 2007-03 8 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00219219

    Zoledronic Acid in the Prevention of Skeletal-related Events in Hormone Refractory and Hormone-sensitive Prostate Cancer Patients With Bone Metastases

    Not yet reported Novartis Est. completion 2006-10 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00219258

    Efficacy and Safety of Zoledronic Acid in Patients With Bone Metastases of Any Solid Tumors or Multiple Myeloma

    Not yet reported Novartis 240 participants 1 site
    Other conditions: Treatment of Bone Metastases
    View official trial listing →
  • Completed NCT NCT00219271

    Effect Of Zoledronic Acid On Circulating And Bone Marrow-Residing Prostate Cancer Cells In Patients With Clinically Localized Prostate Cancer

    Not yet reported Novartis Pharmaceuticals 60 participants Est. completion 2009-09 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00226954

    Zoledronic Acid With Intermittent Hormonal Therapy in Patients With Prostate Cancer

    Not yet reported Stanford University 23 participants Est. completion 2009-02 1 site
    Other conditions: Urologic Neoplasms
    View official trial listing →
  • Completed NCT NCT00237146

    Study to Evaluate Zoledronic Acid on Quality of Life and Skeletal-related Events as Adjuvant Treatment in Patients With Hormone-naïve Prostate Cancer and Bone Metastasis Who Have Undergone Orchiectomy

    Not yet reported Novartis Pharmaceuticals 38 participants Est. completion 2008-03 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00237159

    Effect of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastasis

    Not yet reported Novartis Pharmaceuticals 284 participants
    Other conditions: Prostate Cancer Patients With Bone Metastasis
    View official trial listing →
  • Completed NCT NCT00241111

    Assessment of the Efficacy, Tolerability and Pharmaco-economic Impact of Zoledronic Acid Treatment in Prostate Cancer With Bone Metastasis

    Not yet reported Novartis Pharmaceuticals 148 participants
    Other conditions: Prostate Cancer With Bone Metastasis
    View official trial listing →
  • Completed NCT NCT00242203

    Evaluation of Chemotherapy Prior to Surgery With or Without Zometa for Women With Locally Advanced Breast Cancer

    Not yet reported Washington University School of Medicine 120 participants Est. completion 2011-05 1 site
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Withdrawn NCT NCT00242528

    Open-label Study, to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Bone Lesions Secondary to Multiple Myeloma.

    Not yet reported Novartis
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00242554

    Open-label Phase IV Clinical Trial to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastases

    Not yet reported Novartis Pharmaceuticals 150 participants
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00242567

    Study of Zoledronic Acid for Patients With Hormone-sensitive Bone Metastases From Prostate Cancer

    Not yet reported Novartis Pharmaceuticals 522 participants Est. completion 2012-01 27 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00247650

    Comparison Study of Letrozole Alone or Letrozole With Zoledronic Acid in Early Breast Cancer, Neoadjuvant Therapy

    Not yet reported Novartis 190 participants 10 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT00258258

    Paricalcitol and Zoledronate in Treating Patients With Relapsed or Refractory Multiple Myeloma or Other Plasma Cell Disorders

    Not yet reported Roswell Park Cancer Institute 7 participants 1 site
    Other conditions: Multiple Myeloma and Plasma Cell Neoplasm
    View official trial listing →
  • Terminated NCT NCT00258765

    Adjuvant Docetaxel-Zoledronic Acid in High-risk Early Prostate Cancer Following Prostatectomy.

    Not yet reported Novartis Pharmaceuticals 1 participants 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00263484

    Higher Frequency Zoledronic Acid in the Treatment of Multiple Myeloma

    Not yet reported Gleneagles Hospital 56 participants Est. completion 2010-10 10 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00264082

    Assessment of Tartrate-Resistant Acid Phosphatase (TRAP) as a Bone Resorption Marker in Stage IV Breast Cancer Patients With Bone Metastasis

    University of Louisville 30 participants 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00264420

    Safety and Efficacy Study of Concomitant Radiotherapy and Zoledronic Acid for Bone Metastases Palliation

    Not yet reported The Cleveland Clinic 4 participants Est. completion 2007-03
    Other conditions: Bone Metastases, Breast Cancer, Lung Cancer, Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00265200

    Using TRAP to Evaluate the Effect of Zometa on Bone Metastasis Due to Lung Cancer

    Not yet reported University of Louisville 28 participants Est. completion 2010-12 1 site
    Other conditions: Carcinoma, Non-Small Cell Lung, Carcinoma, Small Cell Lung, Metastases
    View official trial listing →
  • Active, not recruiting NCT NCT00268476

    Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy

    Not yet reported, Not yet reported Medical Research Council 11992 participants Est. completion 2030-12 120 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00278434

    Zoledronate in Treating Patients With Cervical Intraepithelial Neoplasia 2/3 or 3

    Not yet reported University of California, San Francisco 12 participants Est. completion 2008-07 1 site
    Other conditions: Cervical Cancer, Precancerous Condition
    View official trial listing →
  • Completed NCT NCT00287261

    A Trial of Zoledronic Acid in Patients With Myelofibrosis With Myeloid Metaplasia (MMM)

    Not yet reported Universitaire Ziekenhuizen KU Leuven 17 participants Est. completion 2008-03 6 sites
    Other conditions: Myelofibrosis, Myeloid Metaplasia
    View official trial listing →
  • Terminated NCT NCT00294437

    ZOMETA® (Zoledronic Acid) for Prevention of Bone Metastases

    Not yet reported Central European Cooperative Oncology Group 376 participants Est. completion 2007-11 57 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00295646

    Tamoxifen Versus Anastrozole, Alone or in Combination With Zoledronic Acid

    Not yet reported Austrian Breast & Colorectal Cancer Study Group 1803 participants Est. completion 2018-06-26 72 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00295867

    Zoledronate in Treating Bone Marrow Micrometastases in Women With Stage I, Stage II, or Stage III Breast Cancer

    Not yet reported University of California, San Francisco 45 participants Est. completion 2013-12 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00297830

    Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Organ Transplantation

    Not yet reported, Not yet reported Columbia University 111 participants Est. completion 2014-01 1 site
    Other conditions: Heart Transplantation, Liver Transplantation, Bone Resorption
    View official trial listing →
  • Completed NCT NCT00301873

    Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma

    Not yet reported Duke University 60 participants Est. completion 2012-09 1 site
    Other conditions: Brain Tumors, Osteoporosis, Central Nervous System(CNS)Malignancies
    View official trial listing →
  • Withdrawn NCT NCT00301886

    S0308 Zoledronate or Ibandronate in Preventing Bone Problems in Women With Stage IV Breast Cancer That Has Spread to the Bone

    Not yet reported SWOG Cancer Research Network Est. completion 2006-05
    Other conditions: Breast Cancer, Hypercalcemia of Malignancy, Metastatic Cancer, Pain
    View official trial listing →
  • Status unknown NCT NCT00302484

    Use of Bisphosphonates in the Treatment of Osteopathy After Liver Transplantation

    Not yet reported Medical University of Vienna 96 participants 1 site
    Other conditions: Osteoporosis, Liver Transplantation
    View official trial listing →
  • Completed NCT NCT00305695

    Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries

    Not yet reported Gynecologic Oncology Group 160 participants 95 sites
    Other conditions: Hereditary Breast and Ovarian Cancer Syndrome, Osteoporosis, Ovarian Carcinoma
    View official trial listing →
  • Completed NCT NCT00320710

    Continued Efficacy and Safety of Zoledronic Acid (q 4 Wks vs. q 12 Wks) in the 2nd Year of Treatment in Patients With Bone Metastases From Breast Cancer

    Not yet reported Novartis Pharmaceuticals 416 participants Est. completion 2013-07 92 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00321464

    A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.

    Not yet reported Amgen 2049 participants Est. completion 2012-04-04
    Other conditions: Bone Metastases
    View official trial listing →
  • Completed NCT NCT00321620

    Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate Cancer

    Not yet reported Amgen 1904 participants Est. completion 2012-02-24
    Other conditions: Bone Metastases
    View official trial listing →
  • Completed NCT NCT00321932

    Zoledronic Acid in Preventing Osteoporosis in Patients Undergoing Donor Stem Cell Transplant

    Not yet reported University of Minnesota 61 participants Est. completion 2012-03 2 sites
    Other conditions: Leukemia, Lymphoma, Myelodysplastic Syndromes, Osteoporosis, Ovarian Cancer
    View official trial listing →
  • Status unknown NCT NCT00326820

    Ibandronate or Zoledronate in Treating Patients With Newly Diagnosed Bone Metastases From Breast Cancer

    Not yet reported Wales Cancer Trials Unit 1404 participants Est. completion 2015-10 79 sites
    Other conditions: Breast Cancer, Hypercalcemia of Malignancy, Metastatic Cancer
    View official trial listing →
  • Completed NCT NCT00329797

    Zoledronate in Preventing Osteoporosis and Bone Fractures in Patients With Locally Advanced Nonmetastatic Prostate Cancer Undergoing Radiation Therapy and Hormone Therapy

    Not yet reported Radiation Therapy Oncology Group 109 participants Est. completion 2014-11 88 sites
    Other conditions: Osteoporosis, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00330759

    Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma.

    Not yet reported Amgen 1779 participants Est. completion 2011-10-01
    Other conditions: Bone Metastases
    View official trial listing →
  • Completed NCT NCT00332709

    Safety/Efficacy of Letrozole Monotherapy or in Combination With Zoledronic Acid as Extended Adjuvant Treatment of Postmenopausal Patients With Primary Breast Cancer

    Not yet reported Novartis 83 participants Est. completion 2010-08 23 sites
    Other conditions: Osteoporosis, Postmenopausal
    View official trial listing →
  • Terminated NCT NCT00333229

    A Study of Zoledronic Acid in the Prevention of Cancer Therapy-induced Bone Loss

    Not yet reported Novartis Pharmaceuticals 11 participants Est. completion 2013-12 1 site
    Other conditions: Primary Hormone Receptor Negative Breast Cancer in Premenopausal Women
    View official trial listing →
  • Completed NCT NCT00334139

    Effect of Zoledronic Acid on Bone Metabolism in Patients With Bone Metastasis and Prostate or Breast Cancer

    Not yet reported Novartis Pharmaceuticals 411 participants Est. completion 2009-07 1 site
    Other conditions: Prostate Cancer, Breast Cancer, Bone Metastasis
    View official trial listing →
  • Completed NCT NCT00346242

    Evaluation of Efficacy of Zoledronic Acid in Patients With Haemoglobin Syndromes (Thalassemia and Sicle Cell Anaemia) and Risk of Skeletal Events

    Not yet reported Novartis Pharmaceuticals 60 participants 1 site
    Other conditions: Thalassemia
    View official trial listing →
  • Completed NCT NCT00352846

    Effect of Zoledronic Acid on Chemotherapy Induced Bone Loss

    Not yet reported M.D. Anderson Cancer Center 135 participants Est. completion 2011-09 1 site
    Other conditions: Non-Hodgkin's Lymphoma, Lymphoma
    View official trial listing →
  • Completed NCT NCT00361595

    Intervenous (IV) Zoledronic Acid After Forteo in Postmenopausal Women

    Not yet reported The Cleveland Clinic 35 participants Est. completion 2008-04 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00365105

    Zoledronate, Vitamin D, and Calcium With or Without Strontium 89 or Samarium 153 in Preventing or Delaying Bone Problems in Patients With Bone Metastases From Prostate Cancer, Lung Cancer, or Breast Cancer

    Not yet reported Radiation Therapy Oncology Group 261 participants Est. completion 2017-02-27 147 sites
    Other conditions: Breast Cancer, Lung Cancer, Metastatic Cancer, Pain, Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00372710

    Safety/Efficacy of Intravenous Zoledronic Acid When Added to Standard Therapies in Patients With Breast Cancer and Metastatic Bone Lesions

    Not yet reported Novartis 30 participants 1 site
    Other conditions: Breast Cancer With Bone Metastasis
    View official trial listing →
  • Completed NCT NCT00375427

    Safety and Efficacy of Zoledronic Acid in Patients With Breast Cancer With Metastatic Bone Lesions

    Not yet reported Novartis Pharmaceuticals 430 participants 1 site
    Other conditions: Breast Cancer With Bone Metastasis
    View official trial listing →
  • Completed NCT NCT00375505

    The Safety and Efficacy of Zoledronic Acid in the Prevention of Cancer Therapy Induced Bone Loss

    Not yet reported Novartis Pharmaceuticals 70 participants Est. completion 2014-05 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00375648

    Efficacy and Safety of Zoledronic Acid in the Treatment of Bone Metastases-related Pain in Patients With Prostate Cancer

    Not yet reported Novartis Pharmaceuticals 61 participants 1 site
    Other conditions: Pain
    View official trial listing →
  • Terminated NCT NCT00375752

    Efficacy and Safety of Letrozole vs. Letrozole Plus Zoledronic Acid as Endocrine Therapy Before Surgery in Postmenopausal Patients With Breast Cancer

    Not yet reported Novartis Pharmaceuticals 168 participants Est. completion 2010-12-16 27 sites
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Completed NCT NCT00376740

    Effectiveness of Zoledronic Acid in the Prevention of Osteoporosis in Early Breast Cancer Patients Receiving Letrozole

    Not yet reported Soroka University Medical Center 90 participants 2 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00391690

    Evaluation of Bone Markers as Diagnostic Tools for Early Detection of Bone Metastases in Patients With High Risk Prostate Cancer

    Not yet reported Novartis 99 participants 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00391950

    Maintaining Bone Strength in Men With Prostate Cancer

    Not yet reported Novartis 300 participants 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00399802

    A Study to Examine the Effects of an Experimental Drug on Women With Breast Cancer and Metastatic Bone Disease (MBD)(0822-016)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 43 participants Est. completion 2007-12-05
    Other conditions: Breast Cancer, Metastatic Bone Disease
    View official trial listing →
  • Completed NCT NCT00404820

    Safety/Efficacy of Zoledronic Acid and Alendronate on Bone Metabolism in Postmenopausal Women With Osteoporosis

    Not yet reported Novartis 604 participants Est. completion 2008-12 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT00412022

    HOBOE: A Phase 3 Study of Adjuvant Triptorelin and Tamoxifen, Letrozole, or Letrozole and Zoledronic Acid in Premenopausal Patients With Breast Cancer.

    Not yet reported National Cancer Institute, Naples 1294 participants Est. completion 2024-11 20 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00415779

    ZANTE: Zometa and Taxotere in Hormone Refractory Prostate Cancer

    Not yet reported National Cancer Institute, Naples 36 participants Est. completion 2009-07 2 sites
    Other conditions: Metastatic Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00424983

    Study of Zoledronic Acid Administered Monthly Versus Every 3 Months in Multiple Myeloma and Breast Cancer Patients Who Were Treated With Zoledronic Acid the Prior Year

    Not yet reported Novartis Pharmaceuticals 18 participants Est. completion 2009-11 7 sites
    Other conditions: Multiple Myeloma, Breast Cancer
    View official trial listing →
  • Completed NCT NCT00431444

    Effects of Zoledronic Acid and Raloxifene on Bone Turnover Markers in Postmenopausal Women With Low Bone Mineral Density

    Not yet reported Novartis 110 participants Est. completion 2008-07 17 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00432458

    Zoledronate With or Without Thalidomide in Treating Patients With Early Stage Multiple Myeloma

    Not yet reported Mayo Clinic 68 participants Est. completion 2012-04 4 sites
    Other conditions: Multiple Myeloma and Plasma Cell Neoplasm
    View official trial listing →
  • Completed NCT NCT00434317

    Assessment of Pain and Quality of Life in Breast and Prostate Cancer Patients With Bone Metastases

    Not yet reported Novartis 80 participants 4 sites
    Other conditions: Neoplasm Metastasis
    View official trial listing →
  • Completed NCT NCT00434447

    Long Term Efficacy and Safety of Zoledronic Acid Treatment in Patients With Bone Metastases

    Not yet reported Novartis Pharmaceuticals 73 participants 10 sites
    Other conditions: Bone Neoplasms
    View official trial listing →
  • Completed NCT NCT00436917

    Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer

    Not yet reported Mayo Clinic 60 participants Est. completion 2016-05-09 2 sites
    Other conditions: Breast Cancer, Osteoporosis
    View official trial listing →
  • Completed NCT NCT00439244

    Efficacy Study of Zoledronic Acid and Teriparatide Combination Therapy in Women With Osteoporosis

    Not yet reported Novartis 412 participants Est. completion 2009-02 33 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00439647

    Efficacy in Reducing Fractures and Safety of Zoledronic Acid in Men With Osteoporosis

    Not yet reported Novartis Pharmaceuticals 1199 participants Est. completion 2010-10 128 sites
    Other conditions: Male Osteoporosis
    View official trial listing →
  • Terminated NCT NCT00458796

    Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone

    Not yet reported University of Leeds 1500 participants 30 sites
    Other conditions: Breast Cancer, Hypercalcemia of Malignancy, Metastatic Cancer, Musculoskeletal Complications, Pain
    View official trial listing →
  • Active, not recruiting NCT NCT00470223

    Combined Chemotherapy With or Without Zoledronic Acid for Patients With Osteosarcoma

    Not yet reported UNICANCER 318 participants Est. completion 2026-12 37 sites
    Other conditions: Sarcoma
    View official trial listing →
  • Withdrawn NCT NCT00477217

    Zoledronic Acid Treatment of Spontaneous Osteonecrosis of the Knee

    Not yet reported Novartis Est. completion 2009-05 1 site
    Other conditions: Osteonecrosis
    View official trial listing →
  • Completed NCT NCT00482378

    Samarium Sm 153 Lexidronam Pentasodium Combined With Zoledronic Acid or Pamidronate in Treating Patients With Relapsed or Refractory Multiple Myeloma and Bone Pain

    Not yet reported, Not yet reported Mayo Clinic 39 participants Est. completion 2008-12-02 1 site
    Other conditions: Multiple Myeloma and Plasma Cell Neoplasm, Pain
    View official trial listing →
  • Completed NCT NCT00489424

    Acetaminophen or Fluvastatin Compared to Placebo on the Transient Post-Dose Symptoms (PDS) Following an Intravenous (i.v.) Infusion of a Single Dose of Zoledronic Acid 5mg, in Post-menopausal Women With Low Bone Mass

    Not yet reported Novartis Pharmaceuticals 793 participants Est. completion 2007-12 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00489905

    Study on Evaluation of Zoledronic Acid to Prevent Bone Loss in Men Receiving Androgen Deprivation Therapy for Prostate Cancer

    Not yet reported Hospital Authority, Hong Kong 24 participants Est. completion 2008-05 1 site
    Other conditions: Prostatic Neoplasms, Bone Density
    View official trial listing →
  • Completed NCT NCT00490698

    Zoledronate With Atorvastatin in Renal Cell Carcinoma

    Not yet reported M.D. Anderson Cancer Center 11 participants Est. completion 2012-01 1 site
    Other conditions: Kidney Cancer, Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00512993

    Postoperative Use of Zoledronic Acid in Breast Cancer Patients After Neoadjuvant Chemotherapy

    Not yet reported GBG Forschungs GmbH 654 participants Est. completion 2013-11 93 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00520052

    Frequency of Zoledronic Acid to Prevent Further Bone Loss in Osteoporotic Patients Requiring Androgen Deprivation Therapy for Prostate Cancer

    Not yet reported Wirral University Teaching Hospital NHS Trust 58 participants Est. completion 2005-08 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00524849

    Zometa and Circulating Vascular Endothelial Growth Factor (VEGF) in Breast Cancer Patients With Bone Metastasis

    Not yet reported, Not yet reported Fudan University 60 participants Est. completion 2010-01 1 site
    Other conditions: Metastatic Breast Cancer, Bone Metastases
    View official trial listing →
  • Completed NCT NCT00525759

    Investigating the Biological Effects of the Addition of Zoledronic Acid to Pre-operative Chemotherapy in Breast Cancer

    Not yet reported Sheffield Teaching Hospitals NHS Foundation Trust 40 participants Est. completion 2010-01 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00554918

    Docetaxel and Prednisolone With or Without Zoledronic Acid and/or Strontium Chloride Sr 89 in Treating Patients With Prostate Cancer Metastatic to Bone That Has Not Responded to Hormone Therapy

    Not yet reported University Hospital Birmingham 300 participants Est. completion 2013-06 16 sites
    Other conditions: Metastatic Cancer, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00556374

    Study to Determine Treatment Effects of Denosumab in Patients With Breast Cancer Receiving Aromatase Inhibitor Therapy

    Not yet reported Amgen 3420 participants Est. completion 2022-07-26 46 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00558012

    Zoledronic Acid for Osteoporosis in the Elderly

    Not yet reported University of Pittsburgh 181 participants Est. completion 2014-02 1 site
    Other conditions: Osteoporosis, Bone Loss, Fragility Fractures
    View official trial listing →
  • Completed NCT NCT00558272

    Study to Evaluate the Safety and Effects AZD0530 on Prostate and Breast Cancer Subjects With Metastatic Bone Disease

    Not yet reported AstraZeneca 139 participants Est. completion 2012-08 28 sites
    Other conditions: Breast Cancer, Prostate Cancer, Bone Neoplasms
    View official trial listing →
  • Terminated NCT NCT00559897

    Zoledronic Acid and Positron Emission Tomography in Treating Patients With Advanced Non-Small Cell Lung Cancer

    Not yet reported Barbara Ann Karmanos Cancer Institute 6 participants Est. completion 2011-04 1 site
    Other conditions: Lung Cancer, Metastatic Cancer
    View official trial listing →
  • Completed NCT NCT00566618

    Dasatinib in Combination With Zoledronic Acid for the Treatment of Breast Cancer With Bone Metastasis

    Not yet reported, Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2020-11-17 3 sites
    Other conditions: Breast Cancer, Bone Metastases
    View official trial listing →
  • Completed NCT NCT00577642

    Bone Marker Assessment of Multiple Myeloma Patients Treated With Aminobisphosphonates

    Not yet reported Massachusetts General Hospital 29 participants Est. completion 2012-12 1 site
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00580047

    Effects of Zoledronic Acid Versus Alendronate on Bone Loss After Kidney and Kidney/Pancreas Transplants

    Not yet reported University of Nebraska 59 participants Est. completion 2014-07-29 1 site
    Other conditions: Renal Insufficiency
    View official trial listing →
  • Completed NCT NCT00582556

    Zometa on Bone Mineral Density in Prostate Cancer Patients Undergoing Androgen Ablation Therapy

    Not yet reported University of Wisconsin, Madison 44 participants Est. completion 2013-03 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00582790

    Study of IL2 in Combination With Zoledronic Acid in Patients With Kidney Cancer

    Not yet reported University of Wisconsin, Madison 12 participants Est. completion 2008-09 1 site
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT00582920

    Investigation of Changes in Bone Scan Imaging Before and After Intravenous Bisphosphonate Therapy for Osseous Metastases From Breast Cancer

    Not yet reported Memorial Sloan Kettering Cancer Center 10 participants Est. completion 2008-10 1 site
    Other conditions: Osseous Lesions From Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT00588913

    Adoptive Immunotherapy, Aldesleukin, and Zoledronate in Treating Patients With Stage IV Kidney Cancer and Lung Metastases

    Not yet reported, Not yet reported Tokyo Women's Medical University 20 participants Est. completion 2009-08 2 sites
    Other conditions: Kidney Cancer, Metastatic Cancer
    View official trial listing →
  • Completed NCT NCT00622505

    Zoledronic Acid Treatment (Every 4 or 12 Weeks) to Prevent Skeletal Complications in Advanced Multiple Myeloma Participants

    Not yet reported Novartis Pharmaceuticals 121 participants Est. completion 2012-04-03 42 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00636740

    Multi-Center Phase II Study to Compare MER-101 20mg Tablets to Intravenous Zometa 4mg in Male Bisphosphonate-Naive, Hormone Refractory Prostate Cancer Patients

    Not yet reported Merrion Pharmaceuticals, LLC 30 participants Est. completion 2009-02 13 sites
    Other conditions: Hormone-Refractory Prostate Cancer
    View official trial listing →
  • Withdrawn NCT NCT00639392

    Phase 1 Study of Zoledronic Acid in Sickle Cell Disease

    Not yet reported, Not yet reported Virginia Commonwealth University Est. completion 2008-05 1 site
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Completed NCT NCT00668200

    Impact on Reducing the Incidence of Low Serum Calcium by Providing Educational Materials on the Need to Take Daily Supplemental Calcium and Vitamin D to Patients With Paget's Disease Treated With Reclast®

    Not yet reported Novartis Pharmaceuticals 81 participants Est. completion 2012-11 9 sites
    Other conditions: Paget's Disease of the Bone, Hypocalcemia
    View official trial listing →
  • Completed NCT NCT00685646

    Androgen Blockade Therapy With or Without Zoledronic Acid in Treating Patients With Prostate Cancer and Bone Metastases

    Not yet reported Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan 227 participants Est. completion 2014-01 1 site
    Other conditions: Metastatic Cancer, Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT00691236

    Evaluation of Zoledronic Acid as a Single Agent or as an Adjuvant to Chemotherapy in High Grade Osteosarcoma

    Not yet reported, Not yet reported Tata Memorial Hospital 60 participants Est. completion 2013-08 1 site
    Obstructive sleep apnea
    View official trial listing →
  • Completed NCT NCT00697619

    To Evaluate the Efficacy of ZOMETA® in Treatment of Bone Metastases in Patients With Stage IV Nasopharyngeal Cancer

    Not yet reported Sun Yat-sen University 60 participants Est. completion 2009-09 1 site
    Other conditions: Nasopharyngeal Cancer
    View official trial listing →
  • Completed NCT NCT00712985

    Single Dosing of Zoledronic Acid in Cancer Therapy Induced Bone Loss (CTIBL)

    Not yet reported Milton S. Hershey Medical Center 18 participants Est. completion 2011-03 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00718861

    3 yr Efficacy & Safety Study of Zoledronic Acid in Post-menopausal Women With Osteoporosis Treated With Zol Acid for 6 Yrs

    Not yet reported Novartis Pharmaceuticals 190 participants Est. completion 2013-04 57 sites
    Other conditions: Post-menopausal Osteoporosis
    View official trial listing →
  • Completed NCT NCT00731016

    Treatment of the Hutchinson-Gilford Progeria Syndrome With a Combination of Pravastatin and Zoledronic Acid

    Not yet reported Assistance Publique Hopitaux De Marseille 15 participants Est. completion 2013-07 1 site
    Other conditions: Hutchinson-Gilford Progeria Syndrome
    View official trial listing →
  • Completed NCT NCT00733538

    Stage I Multiple Myeloma Treatment

    Not yet reported Centre Hospitalier Universitaire de Nice 89 participants Est. completion 2012-11 1 site
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00740129

    Re-treatment of Participants With Paget's Disease Using Zoledronic Acid

    Not yet reported Novartis Pharmaceuticals 6 participants Est. completion 2011-03-14 11 sites
    Other conditions: Paget's Disease of the Bone
    View official trial listing →
  • Completed NCT NCT00741377

    A Study to Assess BHQ880 in Combination With Zoledronic Acid in Relapsed or Refractory Myeloma Patients

    Not yet reported Novartis Pharmaceuticals 28 participants Est. completion 2011-12 9 sites
    Other conditions: Multiple Myeloma Bone Disease
    View official trial listing →
  • Completed NCT NCT00742924

    Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

    Not yet reported Children's Oncology Group 24 participants 88 sites
    Other conditions: Sarcoma
    View official trial listing →
  • Completed NCT NCT00745485

    Feasibility of Doctors' Rooms-based Infusion of Zoledronic Acid

    Not yet reported Novartis Pharmaceuticals 186 participants 14 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00760370

    Comparison of Zometa Retention and Effect in Multiple Myeloma and Breast Cancer

    Not yet reported Vejle Hospital 60 participants Est. completion 2011-12 2 sites
    Other conditions: Multiple Myeloma, Breast Cancer
    View official trial listing →
  • Completed NCT NCT00762346

    Efficacy and Safety Study of ZOMETA® in Treatment of High-level NTX Non Small Cell Lung Cancer With Bone Metastasis

    Not yet reported Sun Yat-sen University 156 participants Est. completion 2013-03 1 site
    Other conditions: Non Small Cell Lung Cancer, Bone Metastases, High NTX Level
    View official trial listing →
  • Completed NCT NCT00765687

    Screening Non Small Cell Lung Cancer With Bone Metastasis and Efficacy and Safety Research of Receiving Bisphosphonates

    Not yet reported Sun Yat-sen University 432 participants Est. completion 2012-05 1 site
    Other conditions: Non-small Cell Lung Cancer, Bone Metastases
    View official trial listing →
  • Completed NCT NCT00774020

    Efficacy and Safety of Single Dose of 5 mg Zoledronic Acid in Chinese Patients With Paget's Disease of Bone (PDB)

    Not yet reported Novartis Pharmaceuticals 9 participants Est. completion 2011-01-14 4 sites
    Other conditions: Paget's Disease of Bone
    View official trial listing →
  • Status unknown NCT NCT00781261

    Osteonecrosis of the Hip and Bisphosphonate Treatment

    Not yet reported University of Sydney 120 participants Est. completion 2013-12 5 sites
    Other conditions: Osteonecrosis
    View official trial listing →
  • Completed NCT NCT00795483

    Efficacy And Security Of Annual And Biennial Zoledronic Acid For Osteoporosis Treatment In An HIV-Infected Patients' Cohort

    Not yet reported Germans Trias i Pujol Hospital 33 participants Est. completion 2011-11 1 site
    Other conditions: HIV Infections
    View official trial listing →
  • Completed NCT NCT00798473

    Zoledronate for Osteopenia in Pediatric Crohn's

    Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 13 participants Est. completion 2008-11 1 site
    Other conditions: Crohn's Disease, Osteopenia, Osteoporosis
    View official trial listing →
  • Completed NCT NCT00799266

    An Efficacy and Safety Trial of Intravenous Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids

    Not yet reported Novartis Pharmaceuticals 34 participants Est. completion 2018-03-05 12 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT00807963

    Pharmacokinetic, Safety and Tolerability Study of SC Administered Bisphosphonate With rHuPH20 vs Bisphosphonate Alone

    Not yet reported Halozyme Therapeutics 31 participants Est. completion 2009-09-21 1 site
    Other conditions: Risk Factors for or a Diagnosis of Osteoporosis
    View official trial listing →
  • Terminated NCT NCT00844480

    Efficacy and Safety of Zoledronic Acid in Acute Spinal Cord Injury: Prevention of Bone Loss

    Not yet reported Thomas J. Schnitzer 17 participants Est. completion 2016-01 1 site
    Other conditions: Bone Loss
    View official trial listing →
  • Completed NCT NCT00869206

    Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement

    Not yet reported Alliance for Clinical Trials in Oncology 1822 participants Est. completion 2017-01 504 sites
    Other conditions: Breast Adenocarcinoma, DS Stage I Plasma Cell Myeloma, DS Stage II Plasma Cell Myeloma, Metastatic Malignant Neoplasm to the Bone, Pain, Musculoskeletal Complication, Urinary Complications
    View official trial listing →
  • Withdrawn NCT NCT00873808

    S0307A, Long-Term Bone Quality in Women With Breast Cancer Enrolled on Clinical Trial SWOG-S0307

    SWOG Cancer Research Network Est. completion 2010-02 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00874211

    S0702: Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone Metastases

    SWOG Cancer Research Network 3571 participants Est. completion 2019-06 453 sites
    Other conditions: Breast Cancer, Lung Cancer, Metastatic Cancer, Multiple Myeloma, Plasma Cell Neoplasm, Prostate Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00879034

    A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria

    Not yet reported Boston Children's Hospital 5 participants Est. completion 2009-04 1 site
    Other conditions: Progeria, Hutchinson-Gilford Syndrome
    View official trial listing →
  • Completed NCT NCT00885326

    N2007-02:Bevacizumab,Cyclophosphamide,& Zoledronic Acid in Patients W/ Recurrent or Refractory High-Risk Neuroblastoma

    Not yet reported New Approaches to Neuroblastoma Therapy Consortium 29 participants Est. completion 2019-12 15 sites
    Other conditions: Neuroblastoma
    View official trial listing →
  • Terminated NCT NCT00889590

    Adjuvant Zoledronic Acid in High Risk Giant Cell Tumour of Bone (GCT)

    Not yet reported Leiden University Medical Center 15 participants Est. completion 2015-07 4 sites
    Other conditions: Giant Cell Tumor of Bone, Osteoclastoma
    View official trial listing →
  • Terminated NCT NCT00892242

    Perioperative Treatment With Zoledronic Acid in Patients With Resectable Pancreas Cancer

    Not yet reported Washington University School of Medicine 24 participants Est. completion 2013-04 1 site
    Other conditions: Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT00896532

    Romosozumab (AMG 785) in Postmenopausal Women With Low Bone Mineral Density

    Not yet reported Amgen 419 participants Est. completion 2016-02-18
    Other conditions: Low Bone Mineral Density, Postmenopausal Osteoporosis
    View official trial listing →
  • Completed NCT NCT00903162

    Extended Endocrine Therapy for Premenopausal Women With Breast Cancer

    Not yet reported Dana-Farber Cancer Institute 17 participants Est. completion 2014-09 4 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00909961

    A Trial Evaluating the Effects of Zoledronic Acid 5 mg Infusion on Bone Mineral Density (BMD) in Postmenopausal Osteoporosis (PMO) Patients Between the Ages of 50 and 65 Years

    Not yet reported Novartis Pharmaceuticals 118 participants Est. completion 2011-12-16 6 sites
    Other conditions: Postmenopausal Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT00912938

    Evaluate the Relationship of Bone Remodeling Markers for Skeletal Complications in Metastatic Breast Cancer Patients

    Not yet reported Korean Breast Cancer Study Group 237 participants Est. completion 2010-12 1 site
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT00916747

    Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria

    Not yet reported Boston Children's Hospital 85 participants Est. completion 2023-12 1 site
    Other conditions: Progeria
    View official trial listing →
  • Completed NCT NCT00927186

    Effects of Teriparatide or Zoledronic Acid Treatment on Bone in Postmenopausal Osteoporotic Women

    Not yet reported Eli Lilly and Company 69 participants Est. completion 2012-04 12 sites
    Other conditions: Osteoporosis, Post-menopausal
    View official trial listing →
  • Completed NCT NCT00939900

    Efficacy of Zoledronic Acid in Preventing Collapse of the Osteonecrotic Femoral Head

    Not yet reported Seoul National University Bundang Hospital 110 participants Est. completion 2012-06 1 site
    Other conditions: Avascular Necrosis of Femoral Head
    View official trial listing →
  • Completed NCT NCT00950911

    Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only

    Not yet reported Amgen 35 participants Est. completion 2012-04 17 sites
    Other conditions: Bone Metastases in Men With Hormone-Refractory Prostate Cancer, Bone Metastases in Subjects With Advanced Breast Cancer, Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma
    View official trial listing →
  • Terminated NCT NCT00966992

    Study of Zoledronic Acid Versus Observation on Bone Mineral Density and Incidence of Micrometastasis in Women Undergoing Pelvic Radiation for Cervical Cancer

    Not yet reported Washington University School of Medicine 3 participants Est. completion 2010-03 1 site
    Other conditions: Uterine Cervical Neoplasms
    View official trial listing →
  • Completed NCT NCT00972959

    Effect of Combination of Bortezomib/Dexamethasone/Zoledronic Acid on Bone Disease in Patients With Multiple Myeloma Relapsed After 1-3 Prior Lines of Therapy

    Not yet reported University of Athens 17 participants Est. completion 2013-05 3 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00982124

    An Efficacy and Safety Trial of Intravenous Zoledronic Acid in Infants Less Than One Year of Age, With Severe Osteogenesis Imperfecta

    Not yet reported Shriners Hospitals for Children 14 participants Est. completion 2016-04 1 site
    Other conditions: Osteogenesis Imperfecta
    View official trial listing →
  • Completed NCT NCT00984893

    Intra-venous Zoledronic Acid Once Yearly

    Novartis Pharmaceuticals 1551 participants Est. completion 2014-04 3 sites
    Other conditions: Post-Menopausal Osteoporosis
    View official trial listing →
  • Completed NCT NCT00987636

    Study in Localized and Disseminated Ewing Sarcoma

    Not yet reported University Hospital Muenster 907 participants Est. completion 2019-03-31 2 sites
    Other conditions: Ewing's Sarcoma
    View official trial listing →
  • Terminated NCT NCT01004510

    Zometa Adjuvant Treatment of Malignant Pleural Effusion Due To Non-Small Cell Lung Cancer

    Not yet reported Peter Bushunow MD 3 participants Est. completion 2011-04 1 site
    Other conditions: Malignant Pleural Effusion, Non Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT01006395

    Prevention of Micro-architectural Bone Decay in Males With Non-metastatic Prostate Cancer Receiving Androgen Deprivation Therapy (ADT)

    Not yet reported, Not yet reported Austin Health 64 participants Est. completion 2019-04 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT01016093

    Zoledronic Acid for the Prevention of Bone Loss Post-bone Marrow Transplantation for Thalassemia Major Patients

    Not yet reported, Not yet reported Tehran University of Medical Sciences 50 participants Est. completion 2011-12 1 site
    Other conditions: Beta-Thalassemia, Bone Marrow Transplantation
    View official trial listing →
  • Completed NCT NCT01062503

    Duration of Suppression of Bone Turnover Following Treatment With Zoledronic Acid in Men With Metastatic CRPC

    University Health Network, Toronto 48 participants Est. completion 2014-06 1 site
    Other conditions: Metastatic Prostate Cancer, Bone Metastasis
    View official trial listing →
  • Terminated NCT NCT01067989

    Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast Cancer

    Not yet reported HaEmek Medical Center, Israel 22 participants Est. completion 2014-04 1 site
    Other conditions: Chemotherapy, Breast Cancer, Metastatic
    View official trial listing →
  • Completed NCT NCT01087008

    Zoledronic Acid in Patients With Multiple Myeloma and Asymptomatic Biochemical Relapse

    Not yet reported PETHEMA Foundation 103 participants Est. completion 2013-06-05 16 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT01099436

    Neo-Adjuvant Chemotherapy (TAC) With or Without Zoledronic Acid in Treating HER2-negative Breast Cancer Patients

    Not yet reported Borstkanker Onderzoek Groep 250 participants Est. completion 2013-09 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01129336

    Effect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer Patients

    Not yet reported Novartis Pharmaceuticals 44 participants Est. completion 2012-08 33 sites
    Other conditions: First or Second Line HER2-negative Breast Cancer, Metastatic Disease Without Bone Metastasis
    View official trial listing →
  • Completed NCT NCT01153425

    µMRI of Therapeutic Intervention in Postmenopausal Osteoporosis

    Not yet reported University of Pennsylvania 33 participants Est. completion 2012-12 1 site
    Other conditions: Osteoporosis, Osteopenia
    View official trial listing →
  • Terminated NCT NCT01166178

    Zoledronic Acid in MS-patients With Osteoporosis

    Not yet reported Novartis 29 participants Est. completion 2012-06 15 sites
    Other conditions: Osteoporosis, Multiple Sclerosis
    View official trial listing →
  • Completed NCT NCT01194440

    Zoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal Symptoms

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 63 participants Est. completion 2014-01 1 site
    Other conditions: Ductal Carcinoma in Situ, Estrogen Receptor-positive Breast Cancer, Progesterone Receptor-positive Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer
    View official trial listing →
  • Completed NCT NCT01197300

    1 Year Open-label Extension to CZOL446H2337 Safety and Efficacy Trial of Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids

    Not yet reported Novartis Pharmaceuticals 25 participants Est. completion 2019-02-27 10 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT01204203

    Pilot Study of Bisphosphonate Therapy (Zoledronic Acid) in Patients With Malignant Mesothelioma (UAB 0901)

    Not yet reported University of Alabama at Birmingham 8 participants Est. completion 2016-04 1 site
    Other conditions: Mesothelioma
    View official trial listing →
  • Completed NCT NCT01205646

    PET Scanning to Evaluate Zoledronate Efficacy in Metastatic Prostate Cancer

    Not yet reported Barbara Ann Karmanos Cancer Institute 11 participants Est. completion 2015-08 2 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01215344

    First Autologous Transplant on Minimal Residual Disease Markers in Previously Untreated Myeloma Undergoing Initial Treatment With Velcade

    Not yet reported Vanderbilt-Ingram Cancer Center 36 participants Est. completion 2018-03 2 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT01218035

    Efficacy of Zoledronic Acid in Enhancement of Early Stability of Cementless Primary Hip Prosthesis

    Not yet reported Turku University Hospital 49 participants Est. completion 2011-06 1 site
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT01219790

    ZOLEDRONIC ASSOCIATED With Hight Hypofractionated Radiotherapy Dose in Bone Metastases Vertebral Prostate Adenocarcinoma

    Not yet reported Institut Cancerologie de l'Ouest 30 participants Est. completion 2015-11 3 sites
    Other conditions: Prostate Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT01228318

    Bone Loss and Immune Reconstitution in HIV/AIDS (BLIR-HIV)

    Not yet reported Emory University 63 participants Est. completion 2017-04-13 1 site Stand-alone
    Other conditions: HIV Infection, Bone Loss, Osteopenia, Osteoporosis
    View official trial listing →
  • Completed NCT NCT01234129

    Stem Cell Transplant and Zoledronic Acid Improve Outcome in Previously Untreated Patients With Multiple Myeloma

    Instituto Mexicano del Seguro Social 320 participants Est. completion 2009-12 1 site
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Status unknown NCT NCT01259193

    Clinical Study of Sorafenib and Zoledronic Acid to Treat Advanced HCC

    Not yet reported Fudan University 50 participants Est. completion 2012-07 1 site
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT01267279

    Effect of Zoledronic Acid on Femoral Bone Loss Following Total Hip Arthroplasty

    Not yet reported Spokane Joint Replacement Center 51 participants Est. completion 2014-12
    Other conditions: Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT01310465

    The Effect of Zoledronic Acid to Bone Fusion and Bone Metabolism of Patients With Lumbar Degenerative Disease After Lumbar Interbody Fusion

    Not yet reported Fudan University 50 participants Est. completion 2012-04 1 site
    Other conditions: Image Changes of Lumbar Fusion, Bone Turnover Markers, Bone Mineral Density
    View official trial listing →
  • Completed NCT NCT01330238

    The Efficacy of Zoledronic Acid in Modic Changes-related Low Back Pain (LBP)

    Not yet reported University of Oulu 40 participants Est. completion 2012-03 1 site
    Other conditions: Low Back Pain
    View official trial listing →
  • Withdrawn NCT NCT01332617

    Phase II Study of Simvastatin for Relapsed/Refractory Myeloma

    Not yet reported University of Louisville Est. completion 2019-02
    Other conditions: Myeloma
    View official trial listing →
  • Completed NCT NCT01341262

    THAL-DEX Incorporated Into Double PBSC Autotransplantation for Untreated Multiple Myeloma (MM)

    Not yet reported IRCCS Azienda Ospedaliero-Universitaria di Bologna 378 participants Est. completion 2009-01
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT01344967

    Suppression of Bone Turnover Following Treatment With Zoledronic Acid in Patients With Metastatic Breast Cancer: Duration of Effect

    Not yet reported, Not yet reported University Health Network, Toronto 21 participants Est. completion 2011-12 1 site
    Other conditions: Metastatic Breast Cancer With Bone Involvement
    View official trial listing →
  • Completed NCT NCT01345019

    Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

    Not yet reported Amgen 1718 participants Est. completion 2019-03-29 309 sites
    Other conditions: Cancer, Hematologic Malignancies, Multiple Myeloma, Oncology, Bone Metastases, Multiple Myeloma Bone Lesions
    View official trial listing →
  • Completed NCT NCT01348269

    Assessment of Efficacy of Zoledronic Acid in the Treatment of Bone Marrow Edema Syndrome

    Not yet reported Wuerzburg University Hospital 48 participants Est. completion 2015-08-26 2 sites
    Other conditions: Bone Marrow Edema
    View official trial listing →
  • Completed NCT NCT01367288

    Comparative Study of Neoadjuvant Chemotherapy With and Without Zometa for Management of Locally Advanced Breast Cancers

    Not yet reported Hospices Civils de Lyon 53 participants Est. completion 2014-04 1 site
    Other conditions: Locally Advanced Breast Cancer, Ductal Histologic Type, Without Her 2 Overexpression
    View official trial listing →
  • Terminated NCT NCT01404702

    Pilot Study of Zoledronic Acid and Interleukin-2 for Refractory Pediatric Neuroblastoma

    Not yet reported University of Alabama at Birmingham 4 participants Est. completion 2014-08 1 site
    Other conditions: Neuroblastoma
    View official trial listing →
  • Terminated NCT NCT01409811

    Biomarkers in Tissue Samples From Patients With Newly Diagnosed Breast Cancer Treated With Zoledronic Acid

    Not yet reported City of Hope Medical Center 9 participants Est. completion 2015-02 1 site
    Other conditions: Estrogen Receptor-positive Breast Cancer, Invasive Ductal Breast Carcinoma, Progesterone Receptor-positive Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage IIA Breast Cancer, Stage IIB Breast Cancer
    View official trial listing →
  • Terminated NCT NCT01426555

    FES-Rowing Versus Zoledronic Acid to Improve Bone Health in Spinal Cord Injury (SCI)

    Not yet reported, Not yet reported Antonio Lazzari 70 participants Est. completion 2015-02 2 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT01472146

    ZoNantax - Zolendronic Acid as Neoadjuvant Therapy Plus Anthracycline and Taxane in Locally Advanced Breast Cancer

    Not yet reported Susanne Crocamo 58 participants Est. completion 2017-05 1 site
    Other conditions: Breast Cancer, Breast Disease, Neoplasms, Neoplasms by Site
    View official trial listing →
  • Completed NCT NCT01488851

    Study to Assess Incidence of ONJ in Pts With Bone Mets Starting Zoledronic Acid Treatment

    King Faisal Specialist Hospital & Research Center 100 participants Est. completion 2015-01 1 site
    Other conditions: Cancer
    View official trial listing →
  • Completed NCT NCT01522521

    Study of AK156 in Primary Osteoporosis Patients

    Not yet reported Asahi Kasei Therapeutics Corporation 600 participants Est. completion 2015-01 20 sites
    Other conditions: Osteoporosis
    View official trial listing →
  • Terminated NCT NCT01564121

    Study of the Effect of Zoledronate on Local Recurrence After Surgical Treatment of Giant Cell Tumors of Bone Zométa

    Not yet reported, Not yet reported Nantes University Hospital 24 participants Est. completion 2011-01 1 site
    Other conditions: Giant Cell Tumors of Bone
    View official trial listing →
  • Completed NCT NCT01572545

    Comparative Effect of Zoledronic Acid Versus Denosumab on Serum Sclerostin of Postmenopausal Women With Low Bone Mass

    Not yet reported Aristotle University Of Thessaloniki 91 participants Est. completion 2013-01 3 sites
    Other conditions: Postmenopausal Osteoporosis
    View official trial listing →
  • Terminated NCT NCT01623908

    Bone Loss Treatment From Adjuvant Zoledronate Efficacy

    Not yet reported First Affiliated Hospital, Sun Yat-Sen University 200 participants Est. completion 2013-06 10 sites
    Other conditions: Breast Neoplasms, Bone Loss
    View official trial listing →
  • Completed NCT NCT01642901

    Zoledronic Acid in Acute Spinal Cord Injury

    Not yet reported Thomas Jefferson University 16 participants Est. completion 2018-03 1 site
    Other conditions: Spinal Cord Injury
    View official trial listing →
  • Status unknown NCT NCT01654367

    Research of Zoledronic Acid and Aromatase Inhibitors as Adjuvant Therapy to Breast Cancer

    Not yet reported, Not yet reported Tianjin Medical University 300 participants Est. completion 2013-12 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01656512

    Zometa Study in Pediatric Acute Lymphoblastic Leukemia

    Not yet reported Children's Cancer Hospital Egypt 57357 95 participants Est. completion 2015-08 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT01671774

    Safety and Activity of IMAB362 in Combination With Zoledronic Acid and Interleukin-2 in CLDN18.2-positive Gastric Cancer

    Not yet reported Astellas Pharma Global Development, Inc. 29 participants Est. completion 2014-10-13 9 sites
    Other conditions: CLDN18.2-positive Gastric Adenocarcinoma, CLDN18.2-positive Adenocarcinoma of the Gastroesophageal Junction, CLDN18.2-positive Adenocarcinoma of Esophagus
    View official trial listing →
  • Completed NCT NCT01675089

    Zoledronic Acid to Prevent Bone Loss After Kidney Transplantation

    Not yet reported University of Sao Paulo General Hospital 34 participants Est. completion 2014-05 1 site
    Other conditions: Renal Osteodystrophy
    View official trial listing →
  • Terminated NCT NCT01679080

    The Effect of Treatment With Teriparatide and Zoledronic Acid in Patients With Osteogenesis Imperfecta

    Not yet reported University of Aarhus 9 participants Est. completion 2021-06-01 3 sites
    Other conditions: Osteogenesis Imperfecta
    View official trial listing →
  • Withdrawn NCT NCT01702415

    Zoledronic Acid in Cystic Fibrosis

    Not yet reported Papworth Hospital NHS Foundation Trust Est. completion 2015-12 1 site
    Other conditions: Cystic Fibrosis
    View official trial listing →
  • Completed NCT NCT01721993

    Open Label Dose Escalation Phase I Study to Investigate the Safety and Pharmacokinetics of T121E01F and T121E02F in Healthy Postmenopausal Women

    Not yet reported Thar Pharmaceuticals, Inc 71 participants Est. completion 2014-08 1 site
    Other conditions: Healthy Postmenopausal Women
    View official trial listing →
  • Completed NCT NCT01732770

    Safety and Efficacy Study to Evaluate Denosumab Compared With Zoledronic Acid in Postmenopausal Women With Osteoporosis

    Not yet reported Amgen 643 participants Est. completion 2015-01-07 45 sites
    Other conditions: Post Menopausal Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT01737216

    Pilot Study of Zoledronic Acid in Combination With First-line Chemotherapy in Aged Patients With Lung Cancer

    Not yet reported Hebei Tumor Hospital 100 participants Est. completion 2016-12 1 site
    Other conditions: Lung Cancer
    View official trial listing →
  • Terminated NCT NCT01772719

    Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic Acid

    Not yet reported University of Louisville 7 participants Est. completion 2016-11 1 site
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Status unknown NCT NCT01788176

    The Use of Zoledronic Acid to Complex Regional Pain Syndrome

    Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2016-12 1 site
    Other conditions: Complex Regional Pain Syndromes
    View official trial listing →
  • Terminated NCT NCT01802658

    Bone Demineralization Lesions in the Injured Marrow: Efficacy and Tolerability of Administration Early and Repeated the Zoledronic Acid. Comparative Study, Prospective, Double-blind Controlled (DBMZol)

    Not yet reported Nantes University Hospital 12 participants Est. completion 2016-12 9 sites
    Other conditions: Bone Demineralization Lesions in the Injured Marrow
    View official trial listing →
  • Completed NCT NCT01875458

    Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use

    University of Pennsylvania 314 participants Est. completion 2022-10-30 1 site
    Other conditions: Osteoporosis, With or Without Treatment, Bisphosphonate Treatment, Atypical Femur Fracture, Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT01907880

    The ODYSSEY TRIAL Phase IV Trial Evaluating the Palliative Benefit of Pamidronate or Zoledronic Acid in Breast Cancer

    Not yet reported Ottawa Hospital Research Institute 74 participants Est. completion 2016-01 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01920568

    A Study to Compare Denosumab With Zoledronic Acid in Subjects With Bone Metastases From Solid Tumors

    Not yet reported GlaxoSmithKline 487 participants Est. completion 2016-04 25 sites
    Other conditions: Fractures, Bone
    View official trial listing →
  • Completed NCT NCT01951586

    Denosumab in Combination With Chemotherapy as First-line Treatment of Metastatic Non-small Cell Lung Cancer

    Not yet reported Amgen 226 participants Est. completion 2017-11-28 74 sites
    Other conditions: Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT01967160

    Osteonecrosis of the Jaw (ONJ) and Infection Among Nordic Cancer Patients Treated With XGEVA™ or Zoledronic Acid

    Amgen 2560 participants Est. completion 2019-08-05
    Other conditions: Osteonecrosis of the Jaw, Infection Leading to Hospitalization
    View official trial listing →
  • Completed NCT NCT02042872

    Zoledronic Acid Administration in Acute Spinal Cord Injury

    Not yet reported James J. Peters Veterans Affairs Medical Center 21 participants Est. completion 2012-07 1 site Stand-alone
    Other conditions: Disuse Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT02044978

    Initial Fixation of Bisphosphonate-coated Dental Implants

    Not yet reported Per Aspenberg 16 participants Est. completion 2017-01 2 sites
    Other conditions: Pre-integration Failure of Dental Implant
    View official trial listing →
  • Withdrawn NCT NCT02069340

    Genetics in Predicting Risk of Bisphosphonate-Related Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid

    Not yet reported University of Southern California Est. completion 2021-06 2 sites
    Other conditions: Malignant Neoplasm, Musculoskeletal Complications
    View official trial listing →
  • Terminated NCT NCT02123264

    Zoledronic Acid in Rheumatoid Arthritis

    Not yet reported Carmen Gómez-Vaquero 28 participants Est. completion 2018-06 11 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Completed NCT NCT02176382

    Denosumab and Teriparatide Study (DATA-HD and DATA-EX)

    Not yet reported Massachusetts General Hospital 76 participants Est. completion 2020-02 1 site
    Other conditions: Postmenopausal Osteoporosis
    View official trial listing →
  • Completed NCT NCT02181101

    Simultaneous Study of Gemcitabine-Docetaxel Combination Adjuvant Treatment, as Well as Extended Bisphosphonate and Surveillance-Trial

    Not yet reported Ludwig-Maximilians - University of Munich 3754 participants Est. completion 2013-09 1 site
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Completed NCT NCT02274623

    Effect of CTAP101 Capsules on Ca/iPTH in Advanced Breast/Prostate Cancer Patients Treated With Denosumab/Zoledronic Acid

    Not yet reported OPKO Health, Inc. 33 participants Est. completion 2017-03-17 6 sites
    Other conditions: Breast Cancer, Prostate Cancer, Bone Neoplasms, Hypocalcemia, Hyperparathyroidism, Secondary
    View official trial listing →
  • Completed NCT NCT02286830

    Prolonged Protection From Bone Disease in Multiple Myeloma

    Not yet reported Thomas Lund 158 participants Est. completion 2023-02-16 1 site
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT02325414

    Prevention of Bone Loss After Acute SCI by Zoledronic Acid

    Not yet reported Northwestern University 60 participants Est. completion 2020-08-25 2 sites
    Other conditions: Spinal Cord Injury, Acute Spinal Cord Injury, Bone Loss, Osteoporosis
    View official trial listing →
  • Withdrawn NCT NCT02333344

    The Efficacy Study of Aclasta on Prosthetic Fixation in Postmenopausal Women After THA

    Not yet reported Novartis Pharmaceuticals Est. completion 2020-01-28 1 site
    Other conditions: Prosthetic Fixation After Cementless Total Hip Arthroplasty
    View official trial listing →
  • Terminated NCT NCT02347163

    Pre-operative Zoledronate in Triple Negative Breast Cancer

    Not yet reported Mario Negri Institute for Pharmacological Research 22 participants Est. completion 2018-06-08 4 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Withdrawn NCT NCT02451462

    Pilot Trial of Zoledronic Acid to Prevent Bone Loss in Hematopoietic Cell Transplant Recipients

    Not yet reported Stanford University Est. completion 2018-09
    Other conditions: Hematopoietic Stem Cell Transplant, Bone Marrow Transplant
    View official trial listing →
  • Status unknown NCT NCT02480634

    Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer

    Not yet reported Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 280 participants Est. completion 2022-12
    Other conditions: Non-small Cell Lung Cancer, Bone Metastasis
    View official trial listing →
  • Completed NCT NCT02499237

    Zoledronic Acid to Maintain Bone Mass After Denosumab Discontinuation

    Not yet reported 424 General Military Hospital 57 participants Est. completion 2018-11-26 2 sites
    Other conditions: Postmenopausal Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT02504008

    CREATE-1: A Study to Assess the Efficacy and Safety of AXS-02 in Patients With CRPS-1

    Not yet reported Axsome Therapeutics, Inc. 190 participants Est. completion 2019-01 44 sites
    Other conditions: Complex Regional Pain Syndrome, Reflex Sympathetic Dystrophy
    View official trial listing →
  • Terminated NCT NCT02516423

    Ixazomib Citrate, Lenalidomide, Dexamethasone, and Zoledronic Acid or Zoledronic Acid Alone After Radiation Therapy in Treating Patients With Solitary Plasmacytoma of Bone

    Not yet reported Alliance for Clinical Trials in Oncology 11 participants Est. completion 2025-09-30 388 sites
    Other conditions: Solitary Osseous Plasmacytoma
    View official trial listing →
  • Completed NCT NCT02517918

    Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma

    Not yet reported Institut Bergonié 23 participants Est. completion 2021-11-16 3 sites
    Obstructive sleep apnea Other conditions: Solid Tumor
    View official trial listing →
  • Completed NCT NCT02520362

    Denosumab Safety Assessment in Multiple Observational Databases

    Amgen 517991 participants Est. completion 2023-07-21
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT02589600

    Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)

    Not yet reported Susan L. Greenspan 310 participants Est. completion 2022-06-22 1 site Stand-alone
    Other conditions: Osteoporotic Fractures, Osteoporosis, Postmenopausal
    View official trial listing →
  • Status unknown NCT NCT02595138

    Zoledronic Acid as Adjuvant Treatment of Triple-negative Breast Cancer

    Not yet reported Chinese Academy of Medical Sciences 430 participants Est. completion 2023-12
    Other conditions: Triple Negative Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT02622607

    Preventive Effects of Zoledronic Acid on Bone Metastasis in Patients With Stage IIIB and IV Lung Cancer

    Not yet reported Tang-Du Hospital 200 participants Est. completion 2018-03 1 site
    Other conditions: Lung Cancer
    View official trial listing →
  • Withdrawn NCT NCT02632903

    Intravenous Zoledronic Acid for the Treatment of Osteoporosis and Osteonecrosis in Children With Leukemia: A Pilot Study

    Not yet reported Children's Hospital of Eastern Ontario Est. completion 2018-08-20 1 site
    Other conditions: Osteoporosis, Osteonecrosis, Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT02632916

    Denosumab for the Treatment of Osteoporosis in Children: A Pilot Study

    Not yet reported Children's Hospital of Eastern Ontario 10 participants Est. completion 2020-02-03 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT02721433

    4-weekly Versus 12-weekly Administration of Bone-targeted Agents in Patients With Bone Metastases

    Not yet reported Ottawa Hospital Research Institute 263 participants Est. completion 2020-04 1 site
    Other conditions: Breast Cancer, Prostate Cancer, Metastasis
    View official trial listing →
  • Status unknown NCT NCT02721940

    Mononuclear Cells, Platelets and Zoledronic Acid for Preventing Collapse of the Femoral Head in Osteonecrosis

    Not yet reported Chinese PLA General Hospital 100 participants Est. completion 2016-05
    Other conditions: Osteonecrosis
    View official trial listing →
  • Completed NCT NCT02731040

    Exome Sequencing for Atypical Femoral Fractures

    Washington University School of Medicine 38 participants Est. completion 2018-03-29
    Other conditions: Atypical Femoral Fractures, Osteoporosis, Bisphosphonate Therapy
    View official trial listing →
  • Terminated NCT NCT02739555

    Zoledronic Acid Compared to Percutaneous Treatment in Osteoid Osteoma

    Not yet reported Assistance Publique - Hôpitaux de Paris 15 participants Est. completion 2019-06-28 16 sites
    Other conditions: Osteoid Osteoma
    View official trial listing →
  • Terminated NCT NCT02739594

    Comparison of Ibandronate - Zoledronate Regarding Nephrotoxicity in Multiple Myeloma

    Not yet reported Hoffmann-La Roche 89 participants Est. completion 2009-04 56 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Status unknown NCT NCT02746068

    A Study to Assess the Efficacy and Safety of AXS-02 in Subjects With Knee OA Associated With Bone Marrow Lesions

    Not yet reported Axsome Therapeutics, Inc. 346 participants Est. completion 2020-12 61 sites
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT02784652

    Efficacy of Radiotherapy in Combination With Zoledronic Acid in Bone Metastasis Patients With Gastrointestinal Tumors

    Not yet reported Severance Hospital 60 participants Est. completion 2017-02-28 1 site
    Other conditions: Bone Metastasis, Gastrointestinal Cancer
    View official trial listing →
  • Completed NCT NCT02808988

    Changes of GCF Levels of RANKL and Osteoprotegerin in Postmenopausal Osteoporosis

    Not yet reported Ondokuz Mayıs University 47 participants Est. completion 2015-11
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Completed NCT NCT02823925

    Bisphosphonate Therapy in MONA Spectrum Disorder

    Medical University Innsbruck 3 participants
    Other conditions: Bone Density, Pain, Fracture
    View official trial listing →
  • Completed NCT NCT02838121

    Prevention of Periprosthetic Bone Loss After Total Hip Replacement by Annual Bisphosphonate Therapy

    Not yet reported Mel Shiuann-Sheng Lee 62 participants Est. completion 2016-06 1 site
    Other conditions: Prevention of BMD Loss After THR, Serum Markers of Bone Turnover, Functional Outcomes
    View official trial listing →
  • Terminated NCT NCT03040765

    Denosumab Versus Zoledronic Acid in Thalassemia-Induced Osteoporosis

    Not yet reported Hamad Medical Corporation 17 participants Est. completion 2019-04-08 1 site
    Other conditions: Thalassemia Majors (Beta-Thalassemia Major), Osteoporosis
    View official trial listing →
  • Active, not recruiting NCT NCT03073785

    Hypofractionated Stereotactic Body Radiation & Fluorouracil or Capecitabine for Locally Advanced Pancreatic Cancer

    Not yet reported University of Nebraska 46 participants Est. completion 2027-12 1 site
    Other conditions: Pancreatic Adenocarcinoma, Recurrent Pancreatic Carcinoma, Stage I Pancreatic Cancer AJCC v6 and v7, Stage IA Pancreatic Cancer AJCC v6 and v7, Stage IB Pancreatic Cancer AJCC v6 and v7, Stage II Pancreatic Cancer AJCC v6 and v7, Stage IIA Pancreatic Cancer AJCC v6 and v7, Stage IIB Pancreatic Cancer AJCC v6 and v7, Stage III Pancreatic Cancer AJCC v6 and v7, Stage IV Pancreatic Cancer AJCC v6 and v7
    View official trial listing →
  • Completed NCT NCT03087851

    Treatment With Zoledronic Acid Subsequent to Denosumab in Osteoporosis

    Not yet reported Aarhus University Hospital 61 participants Est. completion 2020-08-01 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT03118570

    A Study in Adult Patients With Type I, III or IV Osteogenesis Imperfecta Treated With BPS804

    Not yet reported Ultragenyx Pharmaceutical Inc 112 participants Est. completion 2020-11-12 25 sites
    Other conditions: Osteogenesis Imperfecta, Type I, Osteogenesis Imperfecta Type III, Osteogenesis Imperfecta Type IV
    View official trial listing →
  • Status unknown NCT NCT03158246

    Generic Zoledronic Acid Versus Original Zoledronic Acid in Postmenopausal Osteoporotic Women

    Not yet reported Cttq 466 participants Est. completion 2020-03-02
    Other conditions: Osteoporosis, Postmenopausal
    View official trial listing →
  • Status unknown NCT NCT03169192

    Diagnosis of Osteogenesis Imperfecta in Children

    Assiut University 40 participants Est. completion 2019-03-01 1 site
    Other conditions: Bone Disease, Metabolic
    View official trial listing →
  • Active, not recruiting NCT NCT03173976

    Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial

    Not yet reported Mohammed Milhem 17 participants Est. completion 2028-05-01 1 site
    Obstructive sleep apnea
    View official trial listing →
  • Status unknown NCT NCT03183557

    Efficacy of Zoledronic Acid in Osteoporosis

    Not yet reported Shinshu University 100 participants Est. completion 2025-06-08 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT03289338

    Zoledronic Acid or Methylprednisolone for Active Charcot's Neuroarthropathy of Foot in Patients With Diabetes Mellitus

    Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 36 participants Est. completion 2018-12-31 1 site
    Other conditions: Charcot Arthropathy, Diabetes Complications
    View official trial listing →
  • Completed NCT NCT03301285

    Efficacy of Zoledronic Acid in Osteoporosis of Children With Multiple Disabilities

    Central Hospital, Nancy, France 60 participants Est. completion 2017-03-31 1 site
    Other conditions: Multiple Disability, Osteoporosis
    View official trial listing →
  • Completed NCT NCT03336983

    Luteinizing Hormone-releasing Hormone Analogue and Enzalutamide +/- Zoledronic Acid in Prostate Cancer Patients

    Not yet reported Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 126 participants Est. completion 2023-04-01 1 site
    Other conditions: Prostate Cancer, Bone Metastases
    View official trial listing →
  • Completed NCT NCT03358017

    Neoadjuvant Zoledronate and Atorvastatin in Triple Negative Breast Cancer

    Not yet reported Mario Negri Institute for Pharmacological Research 54 participants Est. completion 2023-07-25 9 sites
    Other conditions: Triple Negative Breast Cancer
    View official trial listing →
  • Completed NCT NCT03396315

    Bisphosphonates for Prevention of Post-Denosumab Bone Loss

    Not yet reported Columbia University 24 participants Est. completion 2023-06-09 2 sites
    Other conditions: IOP, Osteoporosis
    View official trial listing →
  • Terminated NCT NCT03408652

    Efficacy and Safety of Systemic Treatments of Bone Metastases From Kidney Cancer in Patients Treated With Targeted Therapies

    Not yet reported Centre Leon Berard 1 participants Est. completion 2020-06-22 1 site
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT03424239

    Pilot Study for Zoledronic Acid to Prevent Bone Loss After Bariatric Surgery

    Not yet reported Massachusetts General Hospital 6 participants Est. completion 2020-01-01 1 site
    Other conditions: Bariatric Surgery Candidate
    View official trial listing →
  • Terminated NCT NCT03576599

    Intravenous Bisphosphonate in Stress Fracture Treatment -A Randomised Controlled Double Blinded Multicenter Trial

    Not yet reported Oslo University Hospital 5 participants Est. completion 2019-06-26 1 site
    Other conditions: Stress Fracture Foot, Stress Fracture Ankle
    View official trial listing →
  • Completed NCT NCT03664687

    Comparing a Single-Dose vs. Twice Yearly Zoledronate in Patients With Early Stage Breast Cancer (REaCT-ZOL)

    Not yet reported Ottawa Hospital Research Institute 211 participants Est. completion 2025-03-28 6 sites
    Other conditions: Early-stage Breast Cancer
    View official trial listing →
  • Completed NCT NCT03735537

    Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic Acid

    Not yet reported University of Edinburgh 350 participants Est. completion 2025-03-21 23 sites
    Other conditions: Osteogenesis Imperfecta
    View official trial listing →
  • Withdrawn NCT NCT03812367

    Activity of Pre-Osteoclasts and Osteoclasts Over Time in Postmenopausal Women Treated With Denosumab or Zoledronic Acid

    University of California, Davis Est. completion 2021-12-31 1 site
    Other conditions: Osteoporosis, Postmenopausal
    View official trial listing →
  • Enrolling by invitation NCT NCT03859895

    Zoledronate In the Prevention of Paget's Disease: Long Term Extension

    University of Edinburgh 287 participants Est. completion 2027-05 21 sites
    Other conditions: Paget Disease
    View official trial listing →
  • Completed NCT NCT03862833

    Zoledronic Acid in Combination With Interleukin-2 to Expand Vγ9Vδ2 T Cells After T-replete Haplo-identical Allotransplant

    Not yet reported Nantes University Hospital 30 participants Est. completion 2023-08-29 1 site
    Other conditions: Hematopoietic Stem Cell Transplantation
    View official trial listing →
  • Completed NCT NCT03868033

    Denosumab Sequential Therapy

    Not yet reported National Taiwan University Hospital 101 participants Est. completion 2023-12-31 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT03924414

    Trial of Parkinson's And Zoledronic Acid

    Not yet reported California Pacific Medical Center Research Institute 2721 participants Est. completion 2026-02-28 77 sites
    Other conditions: Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia With Lewy Bodies
    View official trial listing →
  • Completed NCT NCT03930992

    Efficacy of Zoledronic Acid + Colaren vs Zoledronic Acid + Conventional Treatment for Osteoporosis in HIV+ and HIV- Men

    Not yet reported University of Guadalajara 30 participants Est. completion 2022-10-31 1 site
    Other conditions: Secondary Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT03932071

    Zoledronic Acid in Decrease the Lung Metastatic Rate of Osteosarcoma

    Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 150 participants Est. completion 2023-01-01 1 site
    Other conditions: Lung Metastases, Tumor Necrosis
    View official trial listing →
  • Status unknown NCT NCT03951493

    Multicentre Medical-economic Study Evaluating the Efficacy of Adding ZOlédronique Acid to STERéotaxique Radiotherapy in the Treatment of Vertebral Metastases

    Not yet reported Institut Cancerologie de l'Ouest 225 participants Est. completion 2023-11-01 7 sites
    Other conditions: Vertebral Metastasis
    View official trial listing →
  • Completed NCT NCT04012320

    Efficacy and Safety on the Use of Bisphosphonates in Paediatrics

    Centre Hospitalier Universitaire de Nīmes 99 participants Est. completion 2018-12-31 1 site
    Other conditions: Bone Fragile, Bisphosphonate-Associated Osteonecrosis, Children, Adverse Events
    View official trial listing →
  • Status unknown NCT NCT04034199

    Treating Idiopathic Inflammatory Myopathies Related Reduced Bone Mineral Density With Denosumab or Zoledronic Acid

    Not yet reported Kwong Wah Hospital 40 participants Est. completion 2021-03-31 1 site
    Other conditions: Idiopathic Inflammatory Myopathies, Osteoporosis, Osteopenia
    View official trial listing →
  • Status unknown NCT NCT04045522

    Study on Bisphosphonates Targeting Triple-negative Breast Cancer

    Shengjing Hospital 120 participants Est. completion 2022-08-31 3 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT04085419

    Osteoporosis in Primary Hyperparathyroidism

    Not yet reported University Medical Centre Ljubljana 40 participants Est. completion 2023-05 1 site
    Other conditions: Primary Hyperparathyroidism, Osteoporosis
    View official trial listing →
  • Completed NCT NCT04087096

    Denosumab to Prevent High-Turnover Bone Loss After Bariatric Surgery

    Not yet reported Massachusetts General Hospital 36 participants Est. completion 2024-08-06 2 sites
    Other conditions: Bariatric Surgery Candidate, Bone Loss
    View official trial listing →
  • Status unknown NCT NCT04115397

    Bisphosphonates for the Treatment of Seropositive Musculoskeletal Complaints

    Not yet reported Karolinska Institutet 80 participants Est. completion 2022-12
    Other conditions: Seropositive Muskuloskeletal Complaints
    View official trial listing →
  • Completed NCT NCT04149405

    Alterations of GCF Levels of Sclerostin and DKK-1 in Postmenopausal Osteoporosis

    Not yet reported Ondokuz Mayıs University 43 participants Est. completion 2018-12-28
    Other conditions: Osteoporosis, Postmenopausal, Periodontitis
    View official trial listing →
  • Completed NCT NCT04177940

    Denosumab (DMAB) Discontinuation And Switching In Glucocorticoid-Induced Osteoporosis (GIOP): A Pilot Study

    Not yet reported University of Alabama at Birmingham 45 participants Est. completion 2025-01-14 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Withdrawn NCT NCT04253340

    Study of a Bone Assessment Technique, Bone Mineral Analyser, Concerning the Prediction of Improvement in Bone Status After an Infusion of Zoledronic Acid in Osteoporotic Women

    Not yet reported University Hospital, Rouen Est. completion 2023-03-01
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT04279392

    Healthy Body, Healthy Bones After Bariatric Surgery Trial

    Not yet reported, Not yet reported University of Nebraska 10 participants Est. completion 2022-12-30 1 site
    Other conditions: Bariatric Surgery Candidate, Bone Loss, Bone Resorption
    View official trial listing →
  • Status unknown NCT NCT04303026

    The Effect of Zoledronic Acid on Patients With Osteoarthritis of the Hip

    Not yet reported Vestre Viken Hospital Trust 70 participants Est. completion 2024-06-30 1 site
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT04304755

    Zoledronic Acid as Adjuvant Therapy in Neovascular Age-related Macular Degeneration (Z-AMD)

    Not yet reported Oslo University Hospital 40 participants Est. completion 2024-01-24 2 sites
    Other conditions: Neovascular Age-related Macular Degeneration
    View official trial listing →
  • Status unknown NCT NCT04325776

    A Study of AL2846 Versus Zoledronic Acid in Subjects With Advanced Non-Small Cell Lung Cancer With Bone Metastasis

    Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 60 participants Est. completion 2021-11 8 sites
    Other conditions: Bone Metastatic Non-small Cell Lung Cancer
    View official trial listing →
  • Enrolling by invitation NCT NCT04488614

    Prospective Breast Cancer Biobanking

    Helse Stavanger HF 1200 participants Est. completion 2030-07-15 2 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT04498715

    Trochanteric Femur Fracture Operated With Dynamic Hip Screw System (DHS) Augmented With a Biphasic Apatite Sulphate Combined With Systemic or Local Bisphosphonate

    Not yet reported Lithuanian University of Health Sciences 20 participants Est. completion 2024-12 1 site
    Other conditions: Trochanteric Fracture of Femur
    View official trial listing →
  • Active, not recruiting NCT NCT04549207

    Comparing Continuation or De-escalation of Bone Modifying Agents (BMA) in Patients Treated for Over 2 Years for Bone Metastases From Either Breast or Castration-resistant Prostate Cancer

    Not yet reported Ottawa Hospital Research Institute 240 participants Est. completion 2026-09 5 sites
    Other conditions: Breast Cancer, Castration-resistant Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT04597931

    Evaluation of Romosozumab vs. Zoledronic Acid Effect in Patients With Spinal Cord Injury and Low Bone Mineral Density

    Not yet reported Sheba Medical Center 30 participants Est. completion 2023-11-15
    Other conditions: Osteoporosis Fracture, Spinal Cord Injuries
    View official trial listing →
  • Status unknown NCT NCT04652128

    Effect of Zoledronic Acid on Prevention of Bone Loss in Acute Phase First-ever Stroke Patients

    Not yet reported Yonsei University 56 participants Est. completion 2023-02 1 site
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT04719481

    Pravastatin Reduces Acute Phase Response of Zoledronic Acid

    Not yet reported Peking University Third Hospital 110 participants Est. completion 2022-04
    Other conditions: Postmenopausal Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT04719572

    Intervention Study of Drugs in Patients Osteopenia and Osteoporosis

    Not yet reported Chinese PLA General Hospital 180 participants Est. completion 2023-01 1 site
    Other conditions: Osteoporosis, Osteopenia, Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT04719650

    Clinical Pharmacokinetics and Pharmacodynamics Study of Different Doses of Zoledronic Acid

    Not yet reported Peking University Third Hospital 64 participants Est. completion 2024-11
    Other conditions: Postmenopausal Osteoporosis
    View official trial listing →
  • Completed NCT NCT04736693

    Replication of the HORIZON Pivotal Fracture Trial in Healthcare Claims Data

    Brigham and Women's Hospital 18028 participants Est. completion 2021-02-18 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT04742010

    Zoledronic Acid for Prevention of Bone Loss After BAriatric Surgery (ZABAS)

    Not yet reported Stinus Gadegaard Hansen 59 participants Est. completion 2024-08-12 1 site
    Other conditions: Bone Loss, Muscle Atrophy, Bariatric Surgery
    View official trial listing →
  • Completed NCT NCT04779216

    Effects of Romosozumab on Bone Density in Women With Anorexia Nervosa

    Not yet reported Karen Klahr Miller, MD 30 participants Est. completion 2025-11-17 1 site
    Obstructive sleep apnea Other conditions: Bone Density, Low, Bone Loss, Eating Disorders
    View official trial listing →
  • Status unknown NCT NCT04899713

    NEOZOL_Follow-up Study

    Hospices Civils de Lyon 50 participants Est. completion 2021-12-31 11 sites
    Other conditions: Locally Advanced Breast Cancer
    View official trial listing →
  • Completed NCT NCT05025293

    Zoledronate Early to Hip Fracture Patients - Safe and Effective?

    Not yet reported Lene Bergendal Solberg 228 participants Est. completion 2026-06-11 1 site
    Other conditions: Hip Fractures, Osteoporosis
    View official trial listing →
  • Active, not recruiting NCT NCT05053750

    TAME: A Pilot Study of Weekly Paclitaxel, Bevacizumab, and Tumor Associated Macrophage Targeted Therapy (Zoledronic Acid) in Women With Recurrent, Platinum-resistant, Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

    Not yet reported M.D. Anderson Cancer Center 14 participants Est. completion 2027-02-02 1 site
    Other conditions: Epithelial Ovarian, Fallopian Tube, Primary Peritoneal Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT05058976

    Romosozumab Use to Build Skeletal Integrity

    Not yet reported Susan L. Greenspan 184 participants Est. completion 2027-03-31 1 site
    Other conditions: Osteoporosis, Osteoporosis, Postmenopausal, Osteoporosis Fracture
    View official trial listing →
  • Completed NCT NCT05080790

    Treatment With Dinutuximab Beta, Zoledronic Acid and Low-dose Interleukin (IL-2) in Patients With Leiomyosarcoma

    Not yet reported Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 7 participants Est. completion 2025-01-20 2 sites
    Obstructive sleep apnea
    View official trial listing →
  • Active, not recruiting NCT NCT05091086

    The Optimal Long Term Treatment Strategy of Anti-resorptive Medications

    Not yet reported National Taiwan University Hospital 60 participants Est. completion 2030-12-31 1 site
    Other conditions: Osteoporosis, Bone Mineral Density
    View official trial listing →
  • Completed NCT NCT05091099

    The Optimal Sequential Therapy After Long Term Denosumab Treatment

    Not yet reported National Taiwan University Hospital 44 participants Est. completion 2025-11-14 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT05106517

    Denosumab vs Zoledronic Acid and Osteoporotic Compression Fracture

    Not yet reported, Not yet reported Shenzhen People's Hospital 122 participants Est. completion 2023-03-11 1 site
    Other conditions: Denosumab vs Zoledronate
    View official trial listing →
  • Status unknown NCT NCT05164952

    Delayed Versus Immediate Use Of Zoledronic Acid For Postmenopausal Patients With Early Breast Cancer Who Are Using Adjuvant Letrozole

    Not yet reported Assiut University 50 participants Est. completion 2023-09-30 1 site
    Other conditions: Use of Zoledronic Acid in Breast Cancer
    View official trial listing →
  • Terminated NCT NCT05204836

    Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention Following an Acute Knee Injury

    Not yet reported University of Calgary 4 participants Est. completion 2025-07-03 1 site
    Other conditions: Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries, Osteo Arthritis Knee
    View official trial listing →
  • Completed NCT NCT05328154

    MAGnesium Effect With ANtiosteoporotic Drugs

    Not yet reported University Hospital, Clermont-Ferrand 45 participants Est. completion 2024-12-19 1 site
    Other conditions: Osteoporosis, Postmenopausal
    View official trial listing →
  • Completed NCT NCT05361408

    A Clinical Trial to Evaluate Efficacy of Once or Twice ZOledronic Acid After Different Duration of denOsumMab Administration in Postmenopausal Women With Osteoporosis (ZOOM Study)

    Not yet reported Yonsei University 114 participants Est. completion 2024-02-13 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Completed NCT NCT05366621

    Post-fracture Medication and Mortality

    National Cheng-Kung University Hospital 216155 participants Est. completion 2021-10-31 1 site
    Other conditions: Osteoporosis, Osteoporosis Fracture, Drug Therapy, Mortality, Adherence, Medication
    View official trial listing →
  • Status unknown NCT NCT05405894

    Efficacy of Zoledronic Acid to Prevent Bone Loss Following Denosumab Discontinuation

    University of Calgary 20 participants Est. completion 2025-07-01 1 site
    Other conditions: Osteoporosis, Osteoporosis, Postmenopausal, Osteopenia, Bone Loss
    View official trial listing →
  • Not yet recruiting NCT NCT05480189

    Effect of Zoledronic Acid Treatment on Bone-related Events in Breast Cancer Patients With Bone Metastases: a Prospective, Multicenter, Real-world Study

    Zhejiang Cancer Hospital 1000 participants Est. completion 2027-03-31
    Other conditions: Histologically Confirmed Breast Cancer ,Diagnosis of Bone Metastasis
    View official trial listing →
  • Active, not recruiting NCT NCT05575167

    Single or Repeat Zoledronate Versus Alendronate Following Denosumab (EUROpean Denosumab Effects Consolidation Study)

    424 General Military Hospital 122 participants Est. completion 2027-11 9 sites
    Other conditions: Osteoporosis, Postmenopausal
    View official trial listing →
  • Completed NCT NCT05598606

    Denosumab vs Zoledronate After Vertebroplasty

    Not yet reported Shenzhen People's Hospital 75 participants Est. completion 2023-01-14 1 site
    Other conditions: Denosumab Allergy, Zoledronic Acid Allergy
    View official trial listing →
  • Completed NCT NCT05614778

    Study to Investigate the Efficacy and Safety After Administration of Daewoong Zoledronic Acid for the Purpose of Treatment or Prevention of Osteoporosis

    Daewoong Pharmaceutical Co. LTD. 2881 participants Est. completion 2024-05-31 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT05638399

    Denosumab vs Zoledronate After Lumbar Fusion

    Not yet reported Shenzhen People's Hospital 100 participants Est. completion 2023-02-28 1 site
    Other conditions: Osteopenia, Lumbar Spondylolisthesis
    View official trial listing →
  • Active, not recruiting NCT NCT05655013

    Treatment With Zoledronate Subsequent to Denosumab in Osteoporosis 2 (ZOLARMAB2)

    Not yet reported Aarhus University Hospital 200 participants Est. completion 2027-02-01 1 site
    Other conditions: Osteoporosis, Postmenopausal
    View official trial listing →
  • Active, not recruiting NCT NCT05666310

    Muscle Impact of Treating Osteoporosis

    Not yet reported Nami Safai Haeri 20 participants Est. completion 2026-09-05 1 site
    Other conditions: Sarcopenia, Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT05743179

    The Effect of Zoledronate on the Prevention of Pneumonia in Hip Fracture Patients

    Not yet reported The University of Hong Kong 2692 participants Est. completion 2025-06 5 sites
    Other conditions: Hip Fractures, Pneumonia
    View official trial listing →
  • Status unknown NCT NCT05866172

    HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCC

    Not yet reported Sun Yat-sen University 264 participants Est. completion 2025-06-01 1 site
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Status unknown NCT NCT06023420

    Efficacy of a Herbal Formula for Bone Metastases

    Not yet reported, Not yet reported Chinese University of Hong Kong 36 participants Est. completion 2025-01-01
    Other conditions: Bone Metastases
    View official trial listing →
  • Status unknown NCT NCT06051344

    Effect of Zoledronic Acid in Primary Knee Osteoarthritis

    Not yet reported Toufiqe-E-Ealahi 92 participants Est. completion 2023-12-31 1 site
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT06135298

    FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZA

    Not yet reported Aksaray University 20 participants Est. completion 2026-01-15 1 site
    Other conditions: Trochanteric Fracture of Femur, Osteoporotic Fracture of Femur, Hip Fractures, Bone Density, Low
    View official trial listing →
  • Not yet recruiting NCT NCT06221072

    A Study to Assess the Prevention of Bone-related Events in Patients With Bone Metastases From Malignant Solid Tumors Treated With JMT103 Compared to Zoledronic Acid

    Not yet reported Shanghai JMT-Bio Inc. 1360 participants Est. completion 2028-05-31
    Other conditions: Imaging Examination Shows at Least One Site With Bone Metastases From Soild Tumors
    View official trial listing →
  • Completed NCT NCT06621069

    The Effect of Long-term Use of Bisphosphonates on Femur Morphology

    Second Affiliated Hospital, Zhejiang University, School of Medicine 140 participants Est. completion 2024-08-01 1 site
    Other conditions: Osteoporosis, Knee Osteoarthristis
    View official trial listing →
  • Enrolling by invitation NCT NCT06811363

    Contribution of Bone to Urine Citrate

    University of Texas Southwestern Medical Center 25 participants Est. completion 2027-03 1 site
    Other conditions: Osteoporosis
    View official trial listing →
  • Active, not recruiting NCT NCT06876636

    Zoledronic Acid Combined With EC-T for Triple-Negative Breast Cancer

    Not yet reported Xijing Hospital 99 participants Est. completion 2025-12 1 site
    Other conditions: Breast Cancer Metastatic
    View official trial listing →
  • Not yet recruiting NCT NCT07056478

    RANKL Inhibition to Combat Sarcopenia in Hip Fracture Patients

    Not yet reported Prince of Wales Hospital, Shatin, Hong Kong 130 participants Est. completion 2030-01-01 1 site
    Other conditions: Sarcopenia in Elderly
    View official trial listing →
  • Not yet recruiting NCT NCT07204496

    A Clinical Study on the Safety, Tolerance, and Preliminary Efficacy of γδ-T Cell Injection in the Treatment of Advanced Bladder Cancer

    Shanghai 10th People's Hospital 20 participants Est. completion 2026-12-31
    Other conditions: Advanced Bladder Cancer
    View official trial listing →
  • Completed NCT NCT07546058

    Effect of Local Subperiosteal Zoledronic Acid Injection on the Survival of Orthodontic Miniscrews

    Not yet reported Latakia University 68 participants Est. completion 2026-02-03 1 site
    Other conditions: Orthodontic Appliance Complication
    View official trial listing →
  • Not yet recruiting NCT NCT07668583

    EFFICACY AND SAFETY OF ZOLEDRONATE VERSUS PLACEBO ON PAIN AT WEEK 12 IN PEDIATRIC PATIENTS WITH CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS

    Not yet reported Assistance Publique - Hôpitaux de Paris 30 participants Est. completion 2029-12-31 1 site
    Other conditions: Osteomyelitis Chronic
    View official trial listing →
  • Not yet recruiting NCT NCT07687225

    Surgery vs. No Surgery for Primary Tumor in De Novo Stage IV Breast Cancer With Solitary Bone Metastases

    Not yet reported West China Hospital 216 participants Est. completion 2036-12-31
    Other conditions: Breast Cancer, Stage IV Breast Cancer, Bone Metastases
    View official trial listing →
  • Not yet recruiting NCT NCT07741136

    Pharmacokinetics of Zoledronic Acid in Patients on Dialysis

    Not yet reported University of Campinas, Brazil 24 participants Est. completion 2028-08-15 1 site
    Chronic kidney disease Other conditions: Osteoporosis, Dialysis
    View official trial listing →
  • Not yet recruiting NCT NCT07753317

    Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DM

    Not yet reported Cairo University 30 participants Est. completion 2027-03-01
    Other conditions: Controlled Type 2 Diabetic Patients With Periodontitis
    View official trial listing →
  • Not yet recruiting NCT NCT07772609

    Sequential Treatment With Romosozumab Followed by Denosumab vs. Zoledronic Acid for Gains in HIP BMD

    Not yet reported Sahlgrenska University Hospital 216 participants Est. completion 2031-12-31 9 sites
    Other conditions: Osteoporosis in Post-menopausal Women
    View official trial listing →
  • Completed NCT NCT07823751

    The Role of Bisphosphonate and Simvastatin Combination on Therapeutic Response in Breast Cancer With Bone Metastasis Via Dicckopf-1 Pathway

    Not yet reported Universitas Indonesia 35 participants Est. completion 2026-06-20 1 site
    Other conditions: Breast Cancer With Bone Metastasis
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: Zoledronic Acid /Bag Infusion, Zoledronic Acid 5Mg/Bag 100Ml Infusion, Reclast

Related On The Pen coverage

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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.