About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
YM087
- Company
- Cumberland Pharmaceuticals
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- None currently listed
Efficacy results: Not yet reported
No recruiting studies currently listed
See all studies for this drugData source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Trial details
-
Completed NCT NCT00057356
Safety and Efficacy Study of YM087 (Conivaptan) in Patients With Acute Decompensated Heart Failure
Not yet reported Cumberland Pharmaceuticals 170 participants Est. completion 2004-03 26 sitesHeart failureView official trial listing → -
Completed NCT NCT00379847
An Open-Label Study of YM087 (Conivaptan) in Patients With Euvolemic or Hypervolemic Hyponatremia
Not yet reported Cumberland Pharmaceuticals 251 participants Est. completion 2005-06 28 sitesOther conditions: HyponatremiaView official trial listing → -
Completed NCT NCT00380575
Study of IV YM087 to Assess Efficacy and Safety in Patients With Euvolemic or Hypervolemic Hyponatremia
Not yet reported Cumberland Pharmaceuticals 84 participants Est. completion 2003-02 47 sitesOther conditions: HyponatremiaView official trial listing → -
Completed NCT NCT00435591
A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia
Not yet reported Cumberland Pharmaceuticals 121 participants Est. completion 2008-09 18 sitesOther conditions: Hyponatremia, Euvolemia, HypervolemiaView official trial listing → -
Completed NCT NCT00478192
Study of Efficacy & Safety for 3 Infusion Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia
Not yet reported Cumberland Pharmaceuticals 50 participants Est. completion 2008-08 26 sitesOther conditions: HyponatremiaView official trial listing → -
Completed NCT NCT00492037
Study of Efficacy & Safety of Oral YM087 in Subjects With Euvolemic or Hypervolemic Hyponatremia
Not yet reported Cumberland Pharmaceuticals 83 participants Est. completion 2002-02 29 sitesOther conditions: HyponatremiaView official trial listing → -
Completed NCT NCT00592475
A Study to Assess the Safety and Effects of Intravenous (IV) Conivaptan on the Hepatic Hemodynamic Response in Cirrhotic Patients
Not yet reported Cumberland Pharmaceuticals 20 participants Est. completion 2008-11 1 siteOther conditions: Liver CirrhosisView official trial listing → -
Withdrawn NCT NCT00684164
Safety and Efficacy of Conivaptan for the Correction of Hyponatremia in Neurological Patients
Not yet reported Columbia University Est. completion 2010-06 1 siteOther conditions: HyponatremiaView official trial listing → -
Terminated NCT NCT00727090
Use of Conivaptan (Vaprisol) for Hyponatremic Neuro-ICU Patients
Not yet reported Northwestern University 6 participants Est. completion 2010-02Other conditions: HyponatremiaView official trial listing → -
Withdrawn NCT NCT00806910
Diuretic and Renal Effects of Vaprisol When Administered Along With Furosemide and Nesiritide Continuous Infusion
Not yet reported Albert Einstein Healthcare Network Est. completion 2010-02Heart failureView official trial listing → -
Withdrawn NCT NCT00811486
Body Volume Regulation in Pulmonary Arterial Hypertension With Right Ventricular Failure
Not yet reported University of Colorado, Denver Est. completion 2010-12 1 siteHeart failure Other conditions: Pulmonary HypertensionView official trial listing → -
Terminated NCT NCT00843986
Safety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF)
Not yet reported Cumberland Pharmaceuticals 9 participants Est. completion 2009-08 4 sitesHeart failure Other conditions: HyponatremiaView official trial listing → -
Completed NCT NCT00851227
Study to Compare Conivaptan in Subjects With Mild & Moderate Liver Impairment Versus Subjects With Normal Liver Function
Not yet reported Cumberland Pharmaceuticals 26 participants Est. completion 2010-01 1 siteOther conditions: Liver Disease, HyponatremiaView official trial listing → -
Completed NCT NCT00887627
Study to Compare Conivaptan Pharmacokinetics in Subjects With Mild & Moderate Kidney Function Impairment to Subjects With Normal Kidney Function
Not yet reported Cumberland Pharmaceuticals 25 participants Est. completion 2010-07 1 siteOther conditions: Kidney Diseases, HyponatremiaView official trial listing → -
Status unknown NCT NCT00924014
Comparing the Effects of Conivaptan and Diuretics on Plasma Neurohormones and Renal Blood Flow in Patients With Chronic Congestive Heart Failure
Not yet reported Hennepin County Medical Center, Minneapolis 8 participants Est. completion 2010-03 1 siteHeart failureView official trial listing → -
Completed NCT NCT00930202
Study of the Safety and Efficacy of Conivaptan (Vaprisol®) to Raise Serum Sodium Levels in Patients With Severe Traumatic Brain Injury
Not yet reported University of Washington 10 participants Est. completion 2010-06 1 siteOther conditions: Severe Traumatic Brain InjuryView official trial listing → -
Completed NCT NCT01370148
A Study to Assess the Effect of Severe Hepatic Impairment on the Pharmacokinetics of Intravenous Conivaptan
Not yet reported Cumberland Pharmaceuticals 17 participants Est. completion 2014-02 3 sitesOther conditions: Liver DiseaseView official trial listing → -
Terminated NCT NCT01451411
A Study to Assess the Efficacy, Safety and Pharmacokinetics of Intravenous Conivaptan (Vaprisol®) in Pediatric Subjects With Euvolemic or Hypervolemic Hyponatremia
Not yet reported Cumberland Pharmaceuticals 4 participants Est. completion 2014-01 3 sitesOther conditions: HyponatremiaView official trial listing → -
Completed NCT NCT01752543
Effects on Exercise Hemodynamics of Vasopressin Blockade by Conivaptan Infusion in Heart Failure Patients
Not yet reported Finn Gustafsson 20 participants Est. completion 2015-06 1 siteHeart failureView official trial listing → -
Withdrawn NCT NCT01954290
Study of Stroke Related Edema Treatments
Not yet reported University of Florida Est. completion 2015-09Other conditions: Acute Cerebrovascular Accident, Cerebral EdemaView official trial listing → -
Completed NCT NCT03000283
Conivaptan for the Reduction of Cerebral Edema in Intracerebral Hemorrhage- A Safety and Tolerability Study
Not yet reported Jesse Corry 7 participants Est. completion 2019-04-15 1 siteCardiovascular disease Other conditions: Cerebral Hemorrhage, Cerebral Edema, Intracerebral HemorrhageView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
