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Recruiting
NCT NCT06424288
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Not yet reported
Boehringer Ingelheim
6000 participants
Est. completion 2028-05-22
652 sites
Stand-alone
Heart failure
View official trial listing →
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Recruiting
NCT NCT06531824
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
Not yet reported
Boehringer Ingelheim
11000 participants
Est. completion 2028-08-30
520 sites
Stand-alone
Other conditions: Kidney Disease, Chronic
View official trial listing →
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Recruiting
NCT NCT06935370
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Not yet reported
Boehringer Ingelheim
4200 participants
Est. completion 2029-02-22
588 sites
Stand-alone
Heart failure
View official trial listing →
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Recruiting
NCT NCT07064473
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Not yet reported
Boehringer Ingelheim
11800 participants
Est. completion 2029-12-21
1143 sites
Stand-alone
Type 2 diabetesCardiovascular disease
Other conditions: Hypertension
View official trial listing →
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Recruiting
NCT NCT07304817
Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)
Not yet reported
University Medical Center Groningen
100 participants
Est. completion 2028-02
2 sites
Stand-alone
Chronic kidney diseaseCardiovascular diseaseHeart failure
View official trial listing →
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Completed
NCT NCT02891148
Single Rising Dose Study of BI 690517 in Healthy Volunteers
Not yet reported
Boehringer Ingelheim
50 participants
Est. completion 2016-12-12
1 site
Stand-alone
Other conditions: Healthy
View official trial listing →
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Completed
NCT NCT03100916
This Study Tests How Different Doses of BI 690517 Are Taken up in the Body of Healthy Men. The Study Also Looks at How Food Influences the Amount of BI 690517 in the Blood
Not yet reported
Boehringer Ingelheim
72 participants
Est. completion 2017-11-24
1 site
Stand-alone
Other conditions: Healthy
View official trial listing →
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Completed
NCT NCT03165240
This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Different Doses of BI 690517 Are Taken up in the Body and How Well They Are Tolerated
Not yet reported
Boehringer Ingelheim
62 participants
Est. completion 2020-05-07
40 sites
Stand-alone
Other conditions: Diabetic Nephropathies
View official trial listing →
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Completed
NCT NCT03206632
This Study is Done in Healthy Chinese and Japanese Volunteers; it Looks at How BI 690517 is Taken up in the Body and How Well it is Tolerated
Not yet reported
Boehringer Ingelheim
56 participants
Est. completion 2017-10-13
1 site
Stand-alone
Other conditions: Healthy
View official trial listing →
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Completed
NCT NCT03608072
A Study in Healthy Japanese Men to Test How Different Doses of BI 690517 Are Taken Up in the Body and How Well They Are Tolerated
Not yet reported
Boehringer Ingelheim
36 participants
Est. completion 2019-01-31
1 site
Stand-alone
Other conditions: Healthy
View official trial listing →
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Completed
NCT NCT05182840
A Study to Test Whether Different Doses of BI 690517 Alone or in Combination With Empagliflozin Improve Kidney Function in People With Chronic Kidney Disease
Not yet reported
Boehringer Ingelheim
714 participants
Est. completion 2023-07-10
203 sites
Stand-alone
Other conditions: Kidney Disease, Chronic
View official trial listing →
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Completed
NCT NCT05515588
A Study in Healthy Men to Test How BI 690517 is Taken up and Handled by the Body
Not yet reported
Boehringer Ingelheim
14 participants
Est. completion 2022-11-17
1 site
Stand-alone
Other conditions: Healthy
View official trial listing →
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Completed
NCT NCT05731908
A Study to Test How BI 690517 is Taken up in the Body of People With and Without Liver Problems
Not yet reported
Boehringer Ingelheim
28 participants
Est. completion 2023-04-13
2 sites
Stand-alone
Other conditions: Liver Diseases, Healthy
View official trial listing →
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Completed
NCT NCT06647810
A Study in Healthy People to Test How 2 Different Formulations of BI 690517 Are Taken up in the Body and How Probenecid Influences the Amount of BI 690517 in the Blood
Not yet reported
Boehringer Ingelheim
15 participants
Est. completion 2025-01-07
1 site
Stand-alone
Other conditions: Healthy
View official trial listing →
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Completed
NCT NCT06926660
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease
Not yet reported
Boehringer Ingelheim
492 participants
Est. completion 2026-08-14
157 sites
Stand-alone
Chronic kidney disease
View official trial listing →
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Completed
NCT NCT07035457
A Study in Healthy Men to Compare the Amount of Vicadrostat and Empagliflozin in the Blood When Taken Separately and Together
Not yet reported
Boehringer Ingelheim
15 participants
Est. completion 2025-08-15
1 site
Stand-alone
Other conditions: Healthy
View official trial listing →
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Completed
NCT NCT07133399
A Study in Healthy People to Test How 2 Different Formulations of a Combination Treatment (Vicadrostat and Empagliflozin) Are Taken up in the Body and How Food Influences the Amount of the Medicines in the Blood
Not yet reported
Boehringer Ingelheim
32 participants
Est. completion 2025-10-22
1 site
Stand-alone
Other conditions: Healthy
View official trial listing →
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Completed
NCT NCT07513207
A Study in Healthy People to Test How Vicadrostat Affects the Heart
Not yet reported
Boehringer Ingelheim
45 participants
Est. completion 2026-08-21
1 site
Stand-alone
Other conditions: Healthy
View official trial listing →