About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Vicadrostat
- Company
- Boehringer Ingelheim
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 4 recruiting
Efficacy results: Not yet reported
4 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 7, 2026
Find a Clinical Trial Near Me
See recruiting studies for Vicadrostat and check eligibility with the study team.
Trial details
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Recruiting NCT NCT06424288
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Not yet reported Boehringer Ingelheim 6712 participants Est. completion 2028-05-22 664 sites Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT06935370
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Not yet reported Boehringer Ingelheim 4200 participants Est. completion 2029-02-22 585 sites Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT07064473
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Not yet reported Boehringer Ingelheim 11800 participants Est. completion 2029-12-21 1142 sites Stand-aloneType 2 diabetesCardiovascular disease Other conditions: HypertensionView official trial listing → -
Recruiting NCT NCT07304817
Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)
Not yet reported University Medical Center Groningen 100 participants Est. completion 2028-02 2 sites Stand-aloneChronic kidney diseaseCardiovascular diseaseHeart failureView official trial listing → -
Completed NCT NCT02891148
Single Rising Dose Study of BI 690517 in Healthy Volunteers
Not yet reported Boehringer Ingelheim 50 participants Est. completion 2016-12-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03100916
This Study Tests How Different Doses of BI 690517 Are Taken up in the Body of Healthy Men. The Study Also Looks at How Food Influences the Amount of BI 690517 in the Blood
Not yet reported Boehringer Ingelheim 72 participants Est. completion 2017-11-24 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03165240
This International Study Tests BI 690517 in Patients With Diabetic Kidney Disease. The Study Tests How 3 Different Doses of BI 690517 Are Taken up in the Body and How Well They Are Tolerated
Not yet reported Boehringer Ingelheim 62 participants Est. completion 2020-05-07 40 sites Stand-aloneOther conditions: Diabetic NephropathiesView official trial listing → -
Completed NCT NCT03206632
This Study is Done in Healthy Chinese and Japanese Volunteers; it Looks at How BI 690517 is Taken up in the Body and How Well it is Tolerated
Not yet reported Boehringer Ingelheim 56 participants Est. completion 2017-10-13 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03608072
A Study in Healthy Japanese Men to Test How Different Doses of BI 690517 Are Taken Up in the Body and How Well They Are Tolerated
Not yet reported Boehringer Ingelheim 36 participants Est. completion 2019-01-31 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05182840
A Study to Test Whether Different Doses of BI 690517 Alone or in Combination With Empagliflozin Improve Kidney Function in People With Chronic Kidney Disease
Not yet reported Boehringer Ingelheim 714 participants Est. completion 2023-07-10 203 sites Stand-aloneOther conditions: Kidney Disease, ChronicView official trial listing → -
Completed NCT NCT05515588
A Study in Healthy Men to Test How BI 690517 is Taken up and Handled by the Body
Not yet reported Boehringer Ingelheim 14 participants Est. completion 2022-11-17 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05731908
A Study to Test How BI 690517 is Taken up in the Body of People With and Without Liver Problems
Not yet reported Boehringer Ingelheim 28 participants Est. completion 2023-04-13 2 sites Stand-aloneOther conditions: Liver Diseases, HealthyView official trial listing → -
Active, not recruiting NCT NCT06531824
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
Not yet reported Boehringer Ingelheim 11000 participants Est. completion 2026-12-31 558 sites Stand-aloneOther conditions: Kidney Disease, ChronicView official trial listing → -
Completed NCT NCT06647810
A Study in Healthy People to Test How 2 Different Formulations of BI 690517 Are Taken up in the Body and How Probenecid Influences the Amount of BI 690517 in the Blood
Not yet reported Boehringer Ingelheim 15 participants Est. completion 2025-01-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT06926660
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease
Not yet reported Boehringer Ingelheim 492 participants Est. completion 2026-08-14 157 sites Stand-aloneChronic kidney diseaseView official trial listing → -
Completed NCT NCT07035457
A Study in Healthy Men to Compare the Amount of Vicadrostat and Empagliflozin in the Blood When Taken Separately and Together
Not yet reported Boehringer Ingelheim 15 participants Est. completion 2025-08-15 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT07133399
A Study in Healthy People to Test How 2 Different Formulations of a Combination Treatment (Vicadrostat and Empagliflozin) Are Taken up in the Body and How Food Influences the Amount of the Medicines in the Blood
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2025-10-22 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT07513207
A Study in Healthy People to Test How Vicadrostat Affects the Heart
Not yet reported Boehringer Ingelheim 45 participants Est. completion 2026-08-21 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Not yet recruiting NCT NCT07845630
A Study in Healthy People to Compare How 2 Different Formulations of Vicadrostat / Empagliflozin Tablets Are Taken up in the Body
Not yet reported Boehringer Ingelheim 36 participants Est. completion 2026-12-21 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Not yet recruiting NCT NCT07857772
This Will be a Randomized Comparison of the Proteomic Effects of Vicadrostat/Empagliflozin Versus Empagliflozin and Versus Empagliflozin/Spironolactone in Heart Failure Patients With Preserved Ejection Fraction
Not yet reported Baim Institute for Clinical Research 200 participants Est. completion 2028-09Heart failureView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Vicadrostat, BI 690517
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
