About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Venetoclax
- Company
- Columbia University
- Mechanism
- Mechanism not yet reported
- Route
- Oral
- Recruiting trials
- 310 recruiting
Efficacy results: Not yet reported
310 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 30, 2026
Find a Clinical Trial Near Me
See recruiting studies for Venetoclax and check eligibility with the study team.
Trial details
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Recruiting NCT NCT00501826
Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Not yet reported M.D. Anderson Cancer Center 160 participants Est. completion 2028-10-31 1 site Stand-aloneOther conditions: T Acute Lymphoblastic Leukemia, T Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT02115295
Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 508 participants Est. completion 2030-05-31 1 site Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Myeloid Leukemia, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Blasts 10 Percent or More of Bone Marrow Nucleated Cells, Blasts 10 Percent or More of Peripheral Blood White Cells, de Novo Myelodysplastic Syndrome, Myelodysplastic Syndrome, Previously Treated Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Acute Myeloid Leukemia, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Secondary Acute Myeloid Leukemia, Untreated Adult Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT02416388
Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR
Not yet reported, Not yet reported University Hospital, Angers 3100 participants Est. completion 2032-01 56 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT02781883
Clinical Trial of BP1001 in Combination With With Venetoclax Plus Decitabine in AML
Not yet reported Bio-Path Holdings, Inc. 108 participants Est. completion 2028-12 9 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT03013998
Study of Biomarker-Based Treatment of Acute Myeloid Leukemia
Not yet reported, Not yet reported Beat AML, LLC 3000 participants Est. completion 2032-12 31 sites Stand-aloneOther conditions: Previously Untreated Relapsed Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT03113643
SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Not yet reported Dana-Farber Cancer Institute 72 participants Est. completion 2027-05-31 3 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome, Blastic Plasmacytoid Dendritic Cell NeoplasmView official trial listing → -
Recruiting NCT NCT03214562
Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 116 participants Est. completion 2027-09-30 1 site Stand-aloneOther conditions: High Risk Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT03223610
Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 155 participants Est. completion 2027-12-01 1 site Stand-aloneOther conditions: Lymphoma, Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma, Burkitt LymphomaView official trial listing → -
Recruiting NCT NCT03342144
Study of the Use of Venetoclax in Participants With Chronic Lymphocytic Leukemia (CLL) Under Real-Life Setting
AbbVie 500 participants Est. completion 2030-12 74 sitesOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Recruiting NCT NCT03471260
Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies
Not yet reported, Not yet reported M.D. Anderson Cancer Center 96 participants Est. completion 2027-09-30 4 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Hematopoietic and Lymphoid System Neoplasm, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT03523975
Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma
Not yet reported, Not yet reported City of Hope Medical Center 28 participants Est. completion 2027-06-24 4 sites Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Recruiting NCT NCT03586609
Venetoclax, Cladribine, Low Dose Cytarabine, and Azacitidine in Treating Patients With Previously Untreated Acute Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 145 participants Est. completion 2027-04-30 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT03629171
Liposome-encapsulated Daunorubicin-Cytarabine and Venetoclax in Treating Participants With Relapsed, Refractory or Untreated Acute Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 72 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT03661307
Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome
Not yet reported, Not yet reported M.D. Anderson Cancer Center 73 participants Est. completion 2028-01-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT03680677
Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies
Abramson Cancer Center at Penn Medicine 20 participants Est. completion 2027-11 1 siteOther conditions: Leukemia, Acute, MDSView official trial listing → -
Recruiting NCT NCT03826992
Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia
Not yet reported Children's Hospital Medical Center, Cincinnati 21 participants Est. completion 2028-01 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Recruiting NCT NCT03850574
Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported Aptose Biosciences Inc. 240 participants Est. completion 2027-04 34 sites Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Refractory AML, Relapsed Adult AML, Myelodysplastic Syndrome With Excess Blasts-2, Chronic Myelomonocytic LeukemiaView official trial listing → -
Recruiting NCT NCT03868722
Acalabrutinib and Venetoclax Treatment of Newly Diagnosed Patients With CLL at High Risk of Infection or Early Treatment
Not yet reported, Not yet reported Copenhagen University Hospital, Rigshospitalet 212 participants Est. completion 2030-07-31 7 sites Stand-aloneOther conditions: CLLView official trial listing → -
Recruiting NCT NCT03874052
Ruxolitinib in Combination With Venetoclax With and Without Azacitidine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported Jennifer Saultz 51 participants Est. completion 2027-12-31 3 sites Stand-aloneOther conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Secondary Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Refractory Secondary Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT03986034
Early Clonal Dynamics During Venetoclax Treatment for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 75 participants Est. completion 2026-11-17 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT04068597
Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies
Not yet reported, Not yet reported CellCentric Ltd. 250 participants Est. completion 2027-03-31 39 sites Stand-aloneOther conditions: Haematological Malignancy, Acute Myeloid Leukemia, Non Hodgkin Lymphoma, Multiple Myeloma, Higher-risk Myelodysplastic Syndrome, Peripheral T Cell LymphomaView official trial listing → -
Recruiting NCT NCT04140487
Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm
Not yet reported, Not yet reported M.D. Anderson Cancer Center 97 participants Est. completion 2028-09-01 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelomonocytic Leukemia, Recurrent Myelodysplastic/Myeloproliferative Neoplasm, Refractory Acute Myeloid Leukemia, Refractory Chronic Myelomonocytic Leukemia, Refractory Myelodysplastic/Myeloproliferative NeoplasmView official trial listing → -
Recruiting NCT NCT04169737
Acalabrutinib and Venetoclax With or Without Early Obinutuzumab for the Treatment of High Risk, Recurrent, or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported M.D. Anderson Cancer Center 168 participants Est. completion 2028-07-09 1 site Stand-aloneOther conditions: Recurrent Chronic Lymphocytic Leukemia, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT04216524
Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm
Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Blastic Plasmacytoid Dendritic Cell NeoplasmView official trial listing → -
Recruiting NCT NCT04256317
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
Not yet reported, Not yet reported Taiho Oncology, Inc. 316 participants Est. completion 2028-11-01 73 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, Acute Myeloid Leukemia, Myelodysplastic Syndrome/Neoplasm, Chronic Myelomonocytic LeukemiaView official trial listing → -
Recruiting NCT NCT04269902
Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study
Not yet reported National Cancer Institute (NCI) 247 participants Est. completion 2028-10-01 633 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT04523428
REtreatment With VEnetoclax and Acalabrutinib After Venetoclax Limited Duration (REVEAL)
Not yet reported Stichting Hemato-Oncologie voor Volwassenen Nederland 60 participants Est. completion 2032-12 18 sites Stand-aloneOther conditions: CLL/SLLView official trial listing → -
Recruiting NCT NCT04581512
Study to Evaluate the Safety and Tolerability of EP0042
Not yet reported, Not yet reported Ellipses Pharma 70 participants Est. completion 2027-12 6 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT04588922
Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML
Not yet reported, Not yet reported Sellas Life Sciences Group 160 participants Est. completion 2027-12-31 32 sites Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Recruiting NCT NCT04628026
Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2
Not yet reported University of Ulm 650 participants Est. completion 2032-02 91 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT04708054
Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS
Not yet reported, Not yet reported M.D. Anderson Cancer Center 324 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT04758975
Venetoclax, Rituximab and Ibrutinib in TN Patients With CLL Undetectable Minimal Residual Disease (uMRD) in Treatment-naïve Patients With Chronic Lymphocytic Leukemia (CLL)
Not yet reported Paolo Ghia 55 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Recruiting NCT NCT04774393
Decitabine/Cedazuridine and Venetoclax in Combination With Ivosidenib or Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 84 participants Est. completion 2027-11-29 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT04777916
Prospective Non-interventional Study of Adult Patients With Acute Myeloid Leukemia (AML)
Acute Leukemia French Association 5000 participants Est. completion 2046-04-01 30 sitesOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT04797767
Venetoclax and CLAG-M for the Treatment of Acute Myeloid Leukemia and High-Grade Myeloid Neoplasms
Not yet reported, Not yet reported University of Washington 62 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, Myeloid Neoplasm, Relapsed Acute Biphenotypic Leukemia, Relapsed Acute Myeloid Leukemia, Relapsed Mixed Phenotype Acute Leukemia, Relapsed Myeloid Neoplasm, Refractory Acute Biphenotypic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Mixed Phenotype Acute Leukemia, Refractory Myeloid Neoplasm, Recurrent Myeloid SarcomaView official trial listing → -
Recruiting NCT NCT04840602
Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma
Not yet reported National Cancer Institute (NCI) 92 participants Est. completion 2028-03-31 150 sites Stand-aloneOther conditions: Lymphoplasmacytic Lymphoma, Waldenstrom MacroglobulinemiaView official trial listing → -
Recruiting NCT NCT04855695
Avo In R/R And Previously Untreated MCL
Not yet reported, Not yet reported Austin I Kim 72 participants Est. completion 2027-12-31 3 sites Stand-aloneOther conditions: Mantle Cell Lymphoma, Refractory LymphomaView official trial listing → -
Recruiting NCT NCT04895436
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)
Not yet reported AbbVie 75 participants Est. completion 2029-01 58 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Recruiting NCT NCT04905810
Azacitidine or Decitabine With Venetoclax for Acute Myeloid Leukemia With Prior Hypomethylating Agent Failure
Not yet reported Brian Jonas 20 participants Est. completion 2025-12-01 4 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Recurrent Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT04941716
Acalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, The AVENUE-2 Trial
Not yet reported Fred Hutchinson Cancer Center 20 participants Est. completion 2031-08-10 1 site Stand-aloneOther conditions: Recurrent Chronic Lymphocytic Leukemia, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT04988555
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
Not yet reported, Not yet reported Sumitomo Pharma America, Inc. 606 participants Est. completion 2027-12-31 104 sites Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute, Multiple Myeloma, Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT05010122
ASTX727, Venetoclax, and Gilteritinib for the Treatment of Newly Diagnosed, Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Not yet reported, Not yet reported M.D. Anderson Cancer Center 42 participants Est. completion 2028-01-30 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05010772
Decitabine Alone or in Combination With Venetoclax, Gilteritinib, Enasidenib, or Ivosidenib as Maintenance Therapy for the Treatment of Acute Myeloid Leukemia in Remission
Not yet reported M.D. Anderson Cancer Center 125 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05025098
Precision Therapy Versus Standard Therapy in AML and MDS in Elderly
Not yet reported University Hospital, Akershus 36 participants Est. completion 2027-06-10 1 site Stand-aloneOther conditions: AML, Adult, MDSView official trial listing → -
Recruiting NCT NCT05074355
Study of Venetoclax and Azacitidine in Advanced BCR-ABL Negative Myeloproliferative Neoplasms
Not yet reported University Health Network, Toronto 40 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Myeloproliferative NeoplasmView official trial listing → -
Recruiting NCT NCT05091424
A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia
Not yet reported Hoffmann-La Roche 332 participants Est. completion 2032-02-10 31 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT05099471
Efficacy of Venetoclax in Combination With Rituximab in Waldenström's Macroglobulinemia
Not yet reported Christian Buske 80 participants Est. completion 2033-03 14 sites Stand-aloneOther conditions: Waldenstrom Macroglobulinemia, Treatment NaiveView official trial listing → -
Recruiting NCT NCT05168930
Zanubrutinib and Venetoclax in CLL (ZANU-VEN)
Not yet reported Dana-Farber Cancer Institute 45 participants Est. completion 2028-10-28 4 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)View official trial listing → -
Recruiting NCT NCT05183035
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)
Not yet reported PedAL BCU, LLC 130 participants Est. completion 2031-04 90 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05183854
Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial
Not yet reported University of Utah 61 participants Est. completion 2028-06 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT05184842
Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML
Not yet reported Montefiore Medical Center 91 participants Est. completion 2027-03 3 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, Acute Myeloid Leukemia, Chronic Myelomonocytic LeukemiaView official trial listing → -
Recruiting NCT NCT05197192
A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL
Not yet reported German CLL Study Group 202 participants Est. completion 2028-05 30 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT05211570
AB8939 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported AB Science 78 participants Est. completion 2026-12 10 sites Stand-aloneOther conditions: Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, in Relapse, Myelodysplastic Syndrome Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05246345
Venetoclax Resistance Landscape in Chronic Lymphocytic Leukemia
University Hospital, Clermont-Ferrand 50 participants Est. completion 2027-03 14 sitesOther conditions: Chronic Lymphocytic Leukemia, CLL, Progressive Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, Relapsed Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT05287568
CC-486 and Venetoclax for Acute Myeloid Leukemia
Not yet reported University of Colorado, Denver 35 participants Est. completion 2029-03 2 sites Stand-aloneOther conditions: AMLView official trial listing → -
Recruiting NCT NCT05292664
Venetoclax Basket Trial for High Risk Hematologic Malignancies
Not yet reported Andrew E. Place, MD 30 participants Est. completion 2030-07-02 5 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, de Novo, Myelodysplastic Syndromes, Secondary, Myelodysplastic Syndromes, Previously Treated, Treatment-Related Acute Myeloid Leukemia, Therapy-Related Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia With Failed Remission, Lymphoblastic Lymphoma, in Relapse, Lymphoblastic Lymphoma, Refractory, Acute Leukemia of Ambiguous Lineage in Relapse, Acute Leukemia of Ambiguous LineageView official trial listing → -
Recruiting NCT NCT05305859
Venetoclax Combining Chidamide and Azacitidine (VCA) in the Treatment of R/R AML
Not yet reported The First Affiliated Hospital of Xiamen University 30 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Relapsed Adult AML, Refractory LeukemiaView official trial listing → -
Recruiting NCT NCT05317403
Venetoclax to Augment Epigenetic Modification and Chemotherapy
Not yet reported Medical College of Wisconsin 40 participants Est. completion 2027-01 1 siteOther conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia RefractoryView official trial listing → -
Recruiting NCT NCT05336812
Acalabrutinib in Combination With Venetoclax or Obinutuzumab for the Treatment of Treatment-naive Chronic Lymphocytic Leukemia
Not yet reported Ohio State University Comprehensive Cancer Center 52 participants Est. completion 2026-10-31 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT05342584
Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS
Not yet reported Montefiore Medical Center 99 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT05360160
A Phase I-II Study Investigating the All-Oral Combination of the Menin Inhibitor SNDX-5613 With Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE)
Not yet reported, Not yet reported M.D. Anderson Cancer Center 43 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05365035
A Phase II Study of Cladribine and Low Dose Cytarabine in Combination With Venetoclax, Alternating With Azacitidine and Venetoclax, in Patients With Higher-risk Myeloproliferative Chronic Myelomonocytic Leukemia or Higher-risk Myelodysplastic Syndromes With Excess Blasts
Not yet reported M.D. Anderson Cancer Center 60 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Myelodysplastic Syndromes, Myeloproliferative Chronic Myelomonocytic LeukemiaView official trial listing → -
Recruiting NCT NCT05376111
Study of Venetoclax Combined With Azacitidine Regimen in Newly Diagnosed T-ALL Patients
Not yet reported The First Affiliated Hospital of Soochow University 28 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: T-cell Acute Lymphoblastic Leukemia, RecruitingView official trial listing → -
Recruiting NCT NCT05401097
IDH Targeted/Non- Targeted vs Non-targeted/IDH-targeted Approaches in the Treatment of Newly Diagnosed IDH Mutated AML Patients Not Candidates for Intensive Induction Therapy (I- DATA Study)
Not yet reported Alice Mims 125 participants Est. completion 2029-06-30 4 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05404906
AZA + Venetoclax as Maintenance Therapy in Younger Adults With AML in First Remission
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 124 participants Est. completion 2030-06 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML) in RemissionView official trial listing → -
Recruiting NCT NCT05431257
Azacitidine in Combination With Low Dose Intensity Venetoclax in Patients With AML Incl. Explorative AML Profiling
Not yet reported Copenhagen University Hospital, Rigshospitalet 117 participants Est. completion 2031-09-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05442216
Tagraxofusp and Azacitidine With Venetoclax in Newly Diagnosed Secondary AML After Hypomethylating Agents
Not yet reported Joshua Zeidner 53 participants Est. completion 2031-07-21 7 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05506332
Treatment With ABT-199 (Venetoclax) and Purine Analogues in Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported University Hospital, Antwerp 10 participants Est. completion 2026-12 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia RefractoryView official trial listing → -
Recruiting NCT NCT05529069
Phase II Study of Pirtobrutinib With Venetoclax In Relapsed-Refractory MCL (Mantle Cell Lymphoma) Patients
Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2027-04-28 1 site Stand-aloneOther conditions: Mantle Cell Lymphoma, Non Hodgkin Lymphoma, Hematologic MalignancyView official trial listing → -
Recruiting NCT NCT05530421
Selinexor, Venetoclax, and Dexamethasone (XVenD) in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma
Not yet reported University of Miami 33 participants Est. completion 2030-03-26 3 sites Stand-aloneOther conditions: Relapsed and Refractory Multiple MyelomaView official trial listing → -
Recruiting NCT NCT05536349
Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)
Not yet reported M.D. Anderson Cancer Center 60 participants Est. completion 2028-04-25 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Recruiting NCT NCT05553782
Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers
Not yet reported Brigham and Women's Hospital 30 participants Est. completion 2029-08-01 2 sites Stand-aloneOther conditions: Salivary Gland Cancer, Adenoid Cystic Carcinoma of the Salivary Gland, Squamous Cell Carcinoma of Head and Neck, Head and Neck CancerView official trial listing → -
Recruiting NCT NCT05554393
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)
Not yet reported National Cancer Institute (NCI) 153 participants Est. completion 2027-12-31 187 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05554406
Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)
Not yet reported National Cancer Institute (NCI) 335 participants Est. completion 2027-03-31 227 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy, Acute Myeloid Leukemia, Myelodysplasia-RelatedView official trial listing → -
Recruiting NCT NCT05564390
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Not yet reported National Cancer Institute (NCI) 2000 participants Est. completion 2029-05-15 360 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy, Acute Myeloid Leukemia, Myelodysplasia-Related, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT05566054
Venetoclax and Azacitidine Combined With Chidamide (VAC) for the Treatment of Newly Diagnosed Acute Monocytic Leukemia
Not yet reported The First Affiliated Hospital of Soochow University 92 participants Est. completion 2026-09-30 1 site Stand-aloneOther conditions: Acute Monocytic Leukemia, Newly DiagnosedView official trial listing → -
Recruiting NCT NCT05584761
Unrelated Umbilical Cord Blood Stem Cell Combined With Azacitidine Based Treatment for Advanced MDS,CMML-2 and sAML
Not yet reported, Not yet reported The First Affiliated Hospital with Nanjing Medical University 50 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia-2, Secondary Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05587049
A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Receiving Oral Venetoclax Tablets in Combination With Subcutaneously (SC) or Intravenously (IV) Injected Azacitidine in Colombia
AbbVie 70 participants Est. completion 2026-11 8 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05597306
Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Terrence J Bradley, MD 18 participants Est. completion 2026-11-19 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Acute Myeloid Leukemia, in RelapseView official trial listing → -
Recruiting NCT NCT05603884
VCA Regimen Followed by D-MAG Regimen on the Treatment of Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)
Not yet reported The First Affiliated Hospital of Xiamen University 66 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, AML Stage, AdultView official trial listing → -
Recruiting NCT NCT05657639
CAV Regimen for R/R AML
Not yet reported The First Affiliated Hospital of Soochow University 68 participants Est. completion 2026-10-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05657652
CAV Regimen for R/R Ph- B-ALL
Not yet reported The First Affiliated Hospital of Soochow University 36 participants Est. completion 2026-10 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT05660473
Pediatric-inspired Regimen Combined With Venetoclax for Adolescent and Adult Patients With de Novo Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 100 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Precursor Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Recruiting NCT NCT05668026
Administration of Venetoclax to Promote Apoptosis of HIV-infected Cells and Reduce the Size of the HIV Reservoir Among People Living With HIV on ART
Not yet reported, Not yet reported University of Aarhus 18 participants Est. completion 2027-12-01 2 sites Stand-aloneOther conditions: HIV-1-infectionView official trial listing → -
Recruiting NCT NCT05724121
Observational Study of Cardiac Arrhythmias During Treatment With BTK Inhibitors or Venetoclax
National Heart, Lung, and Blood Institute (NHLBI) 135 participants Est. completion 2027-04-08 1 siteSubstance use disorder Other conditions: Chronic Lymphocytic Leukemia (CLL), Waldenstr(SqrRoot)(Delta)m s Macroglobulinemia, Mantle Cell Lymphoma, Cardiac Arrhythmias, Hematologic MalignanciesView official trial listing → -
Recruiting NCT NCT05725200
Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer
Not yet reported Oslo University Hospital 40 participants Est. completion 2040-12-31 1 site Stand-aloneOther conditions: Metastatic Colorectal CancerView official trial listing → -
Recruiting NCT NCT05735184
A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML
Not yet reported Kura Oncology, Inc. 420 participants Est. completion 2030-04 44 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Mixed Lineage Leukemia Gene Mutation, Refractory AML, AML With Mutated NPM1, Acute Myeloid Leukemia Recurrent, Acute Myeloid Leukemia, in Relapse, NPM1 Mutation, KMT2Ar, Myeloid Sarcoma, Nucleophosmin 1-mutated Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05736965
A Study of Selinexor in Combination With Azacitidine and Venetoclax (SAV Regimen) in Treatment Naïve Participants With Acute Myeloid Leukemia
Not yet reported Shanghai Tong Ren Hospital 58 participants Est. completion 2027-04-30 19 sites Stand-aloneOther conditions: AML, AdultView official trial listing → -
Recruiting NCT NCT05736978
Adaptive Treatment for Acute Myeloid Leukemia Based on D14 MRD Results
Not yet reported Shanghai Tong Ren Hospital 58 participants Est. completion 2027-03-15 4 sites Stand-aloneOther conditions: AML, MRDView official trial listing → -
Recruiting NCT NCT05745714
HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Not yet reported, Not yet reported Princess Maxima Center for Pediatric Oncology 26 participants Est. completion 2032-02-02 33 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) RefractoryView official trial listing → -
Recruiting NCT NCT05751044
HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Not yet reported, Not yet reported Princess Maxima Center for Pediatric Oncology 26 participants Est. completion 2032-02-01 33 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) RefractoryView official trial listing → -
Recruiting NCT NCT05756322
The Safety and Tolerability of LBS-007 in Patients With Relapsed or Resistant Acute Leukaemias
Not yet reported, Not yet reported Lin BioScience, Inc 90 participants Est. completion 2026-12-31 17 sites Stand-aloneOther conditions: Relapsed or Resistant Acute LeukaemiasView official trial listing → -
Recruiting NCT NCT05791409
Venetoclax Treatment (26 Cycles) With 6 Cycles or 12 Cycles of Epcoritamab in Patients With Relapsed or Refractory CLL or SLL
Not yet reported, Not yet reported Stichting Hemato-Oncologie voor Volwassenen Nederland 112 participants Est. completion 2032-12 29 sites Stand-aloneOther conditions: CLL/SLLView official trial listing → -
Recruiting NCT NCT05805098
Venetoclax Combined With Homoharringtonine and Cytarabine in Induction for AML
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 60 participants Est. completion 2028-03-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05807932
Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML
Not yet reported, Not yet reported Heinrich-Heine University, Duesseldorf 38 participants Est. completion 2029-04-30 6 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, Secondary Acute Myeloid Leukemia, Chronic Myelomonocytic LeukemiaView official trial listing → -
Recruiting NCT NCT05834244
A Phase Ib Trial of Azacitidine, Venetoclax and Allogeneic NK Cells for Acute Myeloid Leukemia (ADVENT-AML)
Not yet reported M.D. Anderson Cancer Center 32 participants Est. completion 2028-06-30 2 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05853965
Combination Treatment of Belantamab Mafodotin and Venetoclax in Treatment of Relapsed and Refractory t(11;14) Multiple Myeloma
Not yet reported, Not yet reported Universitätsklinikum Hamburg-Eppendorf 45 participants Est. completion 2028-12 5 sites Stand-aloneOther conditions: Multiple Myeloma, Multiple Myeloma in RelapseView official trial listing → -
Recruiting NCT NCT05861050
Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma
Not yet reported, Not yet reported City of Hope Medical Center 50 participants Est. completion 2027-02-01 3 sites Stand-aloneOther conditions: Blastoid Variant Mantle Cell Lymphoma, Mantle Cell Lymphoma, Pleomorphic Variant Mantle Cell LymphomaView official trial listing → -
Recruiting NCT NCT05870995
Chemotherapy CLAGE-Ven Sequential With Reduced Intensity Conditioning for Refractory Acute Myelodi Leukemia
Not yet reported Shanghai Jiao Tong University School of Medicine 100 participants Est. completion 2026-09-01 3 sites Stand-aloneOther conditions: Refractory LeukemiaView official trial listing → -
Recruiting NCT NCT05881265
Treatment of Chidamide and Venetoclax for Retinoic Acid and Arsenic Resistant Acute Promyelocytic Leukemia
Not yet reported Shanghai Jiao Tong University School of Medicine 30 participants Est. completion 2026-01-01 5 sites Stand-aloneOther conditions: APLView official trial listing → -
Recruiting NCT NCT05901974
Venetoclax Combined With Azactidine in the Treatment of ALAL
Not yet reported Sheng-Li Xue, MD 23 participants Est. completion 2026-03-01 1 site Stand-aloneOther conditions: Acute Leukemia of Ambiguous LineageView official trial listing → -
Recruiting NCT NCT05904106
Venetoclax Plus Azacitidine Versus Intensive Chemotherapy for Fit Patients With Newly Diagnosed NPM1 Mutated AML
Not yet reported Technische Universität Dresden 146 participants Est. completion 2030-09 18 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05909293
Clinical Study Protocol of Maintenance Therapy With Venetoclax in Elderly Patients With AML in First Complete Remission
Not yet reported The First Affiliated Hospital with Nanjing Medical University 100 participants Est. completion 2028-05-30 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05910801
Tafasitamab, Lenalidomide and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma
Not yet reported Academic and Community Cancer Research United 100 participants Est. completion 2030-12-30 2 sites Stand-aloneOther conditions: Recurrent Mantle Cell Lymphoma, Refractory Mantle Cell LymphomaView official trial listing → -
Recruiting NCT NCT05939180
VA vs DA for Newly Diagnosed Hig-risk AML
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 116 participants Est. completion 2028-05-13 2 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05947851
A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).
Not yet reported Merck Sharp & Dohme LLC 735 participants Est. completion 2035-07-01 99 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, Chronic Lymphocytic, Small-Cell Lymphoma, Lymphoma, Small Lymphocytic, CLL, SLLView official trial listing → -
Recruiting NCT NCT05955261
A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 70 participants Est. completion 2034-03 10 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05986240
Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML
Not yet reported Montefiore Medical Center 38 participants Est. completion 2030-03 2 sites Stand-aloneOther conditions: AML/MDS, Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT05999877
PICAROS - Acalabrutinib RWE on 1L CLL in Spain
AstraZeneca 315 participants Est. completion 2029-03-31 49 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT06014489
A Trial to Assess Cobicistat Boosted Venetoclax in Combination With Azacitidine in Adult Patients With Newly Diagnosed AML
Not yet reported Stichting Hemato-Oncologie voor Volwassenen Nederland 142 participants Est. completion 2028-12 19 sites Stand-aloneOther conditions: AML, AdultView official trial listing → -
Recruiting NCT NCT06045819
Relation Between Venetoclax Plasma Concentration and Remission in Adults with Acute Myeloid Leukemia (PREDICLAX)
University Hospital, Caen 100 participants Est. completion 2026-01 1 siteOther conditions: Adult Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06082934
Olverembatinib Plus Venetoclax and Dexamethasone for Treatment-naïve Ph+ Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported Xijing Hospital 30 participants Est. completion 2026-11-01 1 site Stand-aloneOther conditions: Newly-diagnosed Ph+ Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06084819
Clinical Study of Venetoclax Combined With CACAG Regimen in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Chinese PLA General Hospital 200 participants Est. completion 2030-01-31 1 site Stand-aloneOther conditions: Relapsed/Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06115135
A Study of Venetoclax in Combination With Isatuximab and Dexamethasone for Relapsed/Refractory Multiple Myeloma
Not yet reported Oncotherapeutics 39 participants Est. completion 2027-12-31 2 sites Stand-aloneOther conditions: Multiple Myeloma in Relapse, Multiple Myeloma, RefractoryView official trial listing → -
Recruiting NCT NCT06129734
Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant
Not yet reported, Not yet reported Benjamin Tomlinson 20 participants Est. completion 2027-09 2 sites Stand-aloneOther conditions: Myeloid Malignancy, Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06131801
Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution
Children's Hospital Medical Center, Cincinnati 30 participants Est. completion 2027-12-01 6 sitesOther conditions: Hematologic Malignancy, Leukemia, Lymphoma, Acute Lymphocytic Leukemia, ALL, Acute Myelogenous Leukemia, AML, Chronic Myelogenous Leukemia, CML, Myeloproliferative Neoplasm, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, Burkitt Lymphoma, T-cell Lymphoma, B Cell Lymphoma, Peripheral T Cell Lymphoma, Cutaneous B-Cell LymphomaView official trial listing → -
Recruiting NCT NCT06152809
CIML NK Cells With Venetoclax for AML
Not yet reported Dana-Farber Cancer Institute 10 participants Est. completion 2027-11-30 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Recurrent, Leukemia, Leukemia, MyeloidView official trial listing → -
Recruiting NCT NCT06156579
Combination Salvage Therapy With Venetoclax and Decitabine in Relapsed/Refractory AML
Not yet reported University Hospital Tuebingen 27 participants Est. completion 2027-03 1 site Stand-aloneOther conditions: AML, MDSView official trial listing → -
Recruiting NCT NCT06177067
Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 24 participants Est. completion 2029-02 10 sites Stand-aloneOther conditions: Refractory Acute Myeloid Leukemia, Relapsed Acute Myeloid Leukemia, Acute Leukemia of Ambiguous LineageView official trial listing → -
Recruiting NCT NCT06191263
Safety and Efficacy of RVU120 Combined With Venetoclax for Treatment of Relapsed/Refractory AML
Not yet reported Ryvu Therapeutics SA 98 participants Est. completion 2027-08 37 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06191978
A Phase Ia/Ib Open-label, Multiple Dose, Study to Determine the Recommended Dose, Evaluate PKs, PDs, Safety, and Activity of Venetoclax in Combination With Oral Decitabine/Cedazuridine (ASTX727) in Pediatric Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML)
Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06192979
Optimize First-line Treatment for AL Amyloidosis With t (11; 14)
Not yet reported Jin Lu, MD 41 participants Est. completion 2027-03-31 7 sitesOther conditions: Amyloidosis; Systemic, AL AmyloidosisView official trial listing → -
Recruiting NCT NCT06220162
VAC Regimen for AML Patients Who Failed to Response to VA Regimen
Not yet reported The First Affiliated Hospital of Soochow University 32 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06221683
Clinical Study of Induction Therapy Options Based on Molecular Subtyping and MRD in Children and Adolescents With AML
Not yet reported Children's Hospital of Soochow University 500 participants Est. completion 2029-12 13 sites Stand-aloneOther conditions: AML, Childhood, Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06232694
Clinical Study Protocol of IAV-induced Remission Followed by Consolidation Therapy With MDCyta+Ven in ND-AML
Not yet reported The First Affiliated Hospital with Nanjing Medical University 54 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06237192
MRD-associated Non-intensive But Non-interruptive Treatment of Ph-negative Acute Lymphoblastic Leukemia Adult Patients
Not yet reported National Research Center for Hematology, Russia 200 participants Est. completion 2027-09-01 1 site Stand-aloneOther conditions: Precursor Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Recruiting NCT NCT06265545
Multicenter, Platform-type Clinical Study of Refractory/Recurrent Acute Myeloid Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 458 participants Est. completion 2028-06-30 1 site Stand-aloneOther conditions: AML, Refractory, RelapsedView official trial listing → -
Recruiting NCT NCT06279572
Immune Profile of Acute Myeloid Leukemia Patients Receiving Azacitidine Plus Venetoclax Induction Chemotherapy
Mayo Clinic 100 participants Est. completion 2027-12-31 3 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06284486
A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib
Not yet reported, Not yet reported M.D. Anderson Cancer Center 8 participants Est. completion 2028-12-30 4 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06301425
MRD Response-adapted Allo-HSCT for Adverse-risk AML
Not yet reported Peking University People's Hospital 178 participants Est. completion 2028-05-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06317649
Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)
Not yet reported National Cancer Institute (NCI) 147 participants Est. completion 2029-05-15 229 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06317662
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
Not yet reported National Cancer Institute (NCI) 153 participants Est. completion 2028-12-31 117 sites Stand-aloneOther conditions: Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06328179
Clinical Study Protocol for the Treatment of ND-AML and RR-AML With KMT2A Gene Abnormalities Using VHEA.
Not yet reported Huai'an First People's Hospital 34 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06329999
A Prospective, Multicenter, and Exploratory Study of CMGV in the Treatment of Recurrent Adult AML and MDS-EB-2/Elder AML
Not yet reported Ruijin Hospital 78 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Recurrent Adult Acute Myeloid Leukemia, Myelodysplastic Syndrome, Adult Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06357182
Iadademstat in Combination With Azacitidine and Venetoclax in Treating Newly Diagnosed Acute Myeloid Leukemia
Not yet reported OHSU Knight Cancer Institute 30 participants Est. completion 2028-05-29 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome/Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06361329
Comparing the Efficacy of VHAG and Traditional Chemotherapy Regimens in Newly Diagnosed ETP-ALL
Not yet reported First Affiliated Hospital of Zhejiang University 81 participants Est. completion 2027-03-31 1 site Stand-aloneOther conditions: ETP-ALLView official trial listing → -
Recruiting NCT NCT06372717
A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS
Not yet reported Apollo Therapeutics Ltd 100 participants Est. completion 2027-08 9 sites Stand-aloneOther conditions: Acute Myeloid Leukemia Refractory, Myelodysplastic Syndrome Acute Myeloid Leukemia, Myelodysplastic Syndrome With Excess Blasts, Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia (AML), Newly Diagnosed Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT06386302
Chidamide, Venetoclax, and Azacitidine for Newly Diagnosed Acute Myeloid Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 184 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: AML, Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06387121
Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Adult Ph- B-ALL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 53 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Precursor Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Recruiting NCT NCT06390306
The Efficacy and Safety of Third-generation TKIs Combined With Azacitidine and Bcl-2 Inhibitor in Patients With CML-MBP
Peking University People's Hospital 30 participants Est. completion 2027-12-01 15 sitesOther conditions: Chronic Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06390319
Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)
Not yet reported St. Jude Children's Research Hospital 100 participants Est. completion 2033-12 4 sites Stand-aloneOther conditions: T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma, Mixed Phenotype Acute LeukemiaView official trial listing → -
Recruiting NCT NCT06393985
Decitabine, Venetoclax and Blinatumomab for Maintenance Following HSCT in Patients With Ph-Negative B-ALL
Not yet reported The First Affiliated Hospital of Soochow University 30 participants Est. completion 2027-04-25 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06394011
Study of VA Combined With HAAG Regimen in Newly Diagnosed Intermediate and High-risk AML Patients
Not yet reported The First Affiliated Hospital of Soochow University 60 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: Intermediate Risk Acute Myeloid Leukemia, High Risk Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06397027
A Phase I Study Investigating the Combination of the Ziftomenib, Venetoclax and Azacitidine in Pediatric Relapsed and Refractory Acute Leukemias
Not yet reported M.D. Anderson Cancer Center 22 participants Est. completion 2030-12-31 1 site Stand-aloneOther conditions: Refractory Acute Leukemia, Pediatric RelapsedView official trial listing → -
Recruiting NCT NCT06399640
Eltanexor and Venetoclax in Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia
Not yet reported Vanderbilt-Ingram Cancer Center 60 participants Est. completion 2027-10-01 2 sites Stand-aloneOther conditions: Relapsed Myelodysplastic Syndrome, Refractory Myelodysplastic Syndrome, Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06428019
A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)
Not yet reported AbbVie 170 participants Est. completion 2028-03 70 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT06429449
Mitoxantrone for Venetoclax Resistant Acute Myeloid Leukemia
Not yet reported University of Colorado, Denver 30 participants Est. completion 2027-11 1 site Stand-aloneOther conditions: Leukemia, Myeloid Leukemia, Monocytic LeukemiaView official trial listing → -
Recruiting NCT NCT06439199
Biological, Prospective Study Evaluating the Dosage of Plasma Cytokines Including the FLT3 Ligand and IL6 of Patients Treated With Non-intensive Chemotherapy
Nantes University Hospital 60 participants Est. completion 2029-12-15 1 siteOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Chronic Myelomonocytic LeukemiaView official trial listing → -
Recruiting NCT NCT06445959
Phase 1b/2 Study of Decitabine and Venetoclax in Combination With the Targeted Mutant IDH1 Inhibitor Olutasidenib
Not yet reported, Not yet reported M.D. Anderson Cancer Center 78 participants Est. completion 2029-06-30 5 sites Stand-aloneOther conditions: Mutant IDH1 Inhibitor OlutasidenibView official trial listing → -
Recruiting NCT NCT06447090
VMAC+DLI Treatment of Patients With Relapse of AML After Allo-HSCT
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 30 participants Est. completion 2027-10-31 1 siteOther conditions: Relapse Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06448013
A Phase I Study Investigating the Combination of the Menin Inhibitor Ziftomenib With Venetoclax and Gemtuzumab in Pediatric Patients With Acute Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 22 participants Est. completion 2030-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06451861
Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML
Not yet reported Guangdong Provincial People's Hospital 240 participants Est. completion 2027-06-30 13 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06466122
Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi
Not yet reported Kerry Rogers 30 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT06466395
A Phase I Study of Hyper-CVAD In Combination With Venetoclax In Pediatric Patients With Relapsed or Refractory Acute Leukemias That Are of the Lymphoid Lineage Including Bi-Phenotypic or Undifferentiated Leukemias
Not yet reported M.D. Anderson Cancer Center 22 participants Est. completion 2031-12-31 1 site Stand-aloneOther conditions: Refractory Acute Leukemia, Relapsed Acute Leukemia, Undifferentiated Leukemia, Bi-Phenotypic LeukemiaView official trial listing → -
Recruiting NCT NCT06471738
Combination of Zanubrutinib, Rituximab and Venetoclax in Patients With Previously Untreated Follicular Lymphoma
Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2027-06-01 1 site Stand-aloneOther conditions: Ann Arbor Stage II Follicular Lymphoma, Grade 1 Follicular Lymphoma, Ann Arbor Stage III Follicular Lymphoma, Ann Arbor Stage IV Follicular Lymphoma, Grade 2 Follicular Lymphoma, Grade 3a Follicular LymphomaView official trial listing → -
Recruiting NCT NCT06471946
VA Conditioning Regimen Allo-HSCT for Elderly Higher-risk MDS
Not yet reported, Not yet reported Navy General Hospital, Beijing 54 participants Est. completion 2030-09-01 1 site Stand-aloneOther conditions: Higher-risk Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT06481228
Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 82 participants Est. completion 2028-06-01 1 site Stand-aloneOther conditions: Philadelphia Positive Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia, AdultView official trial listing → -
Recruiting NCT NCT06481241
Efficacy and Safety of Chemotherapy Combined With CAR-T Cells in Newly Diagnosed Adult Patients With Ph- B-ALL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 77 participants Est. completion 2028-06 1 site Stand-aloneOther conditions: Philadelphia Chromosome Negative ALL, Acute Lymphoblastic Leukemia, AdultView official trial listing → -
Recruiting NCT NCT06483906
Venetoclax and Azacitidine Combined With Homoharringtonine, Followed by Allo-HSCT for Intermediate and High-risk AML.
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 56 participants Est. completion 2028-07-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06496308
Bendamustine and Rituximab With or Without Orelabrutinib in MCL Treatment
Not yet reported Ruijin Hospital 78 participants Est. completion 2027-07-10 1 siteOther conditions: Mantle Cell Lymphoma (MCL)View official trial listing → -
Recruiting NCT NCT06501196
A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome
Not yet reported BlossomHill Therapeutics 170 participants Est. completion 2027-06 13 sites Stand-aloneOther conditions: Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute, Preleukemia, Myelodysplastic Syndromes, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06504459
Venetoclax in Combination With Cladribine and Cytarabine Alternating With Azacitidine Plus Venetoclax for the Treatment of Newly Diagnosed Monocytic AML and Active Signaling Mutated AML
Not yet reported OHSU Knight Cancer Institute 40 participants Est. completion 2028-05-01 2 sites Stand-aloneOther conditions: Acute Monocytic Leukemia, Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06510309
Rituximab Plus Venetoclax in Front Line Marginal Zone Lymphoma
Not yet reported Gottfried von Keudell, MD PhD 33 participants Est. completion 2031-10-01 1 site Stand-aloneOther conditions: Lymphoma, Marginal Zone Lymphoma, MZLView official trial listing → -
Recruiting NCT NCT06511882
Discontinuation of Hypomethylating Agent and Venetoclax in Patients With AML MRD
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 37 participants Est. completion 2028-08 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06520098
A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Not yet reported VA Office of Research and Development 100 participants Est. completion 2030-12-31 4 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT06532552
Comparison of VA (Venetoclax, Azacitidine), VACl (VA, Cladribine), VACh (VA, Chidamide), and Alternating VACl/VACh in Newly Diagnosed Acute Myeloid Leukemia
Not yet reported The First Affiliated Hospital of Soochow University 172 participants Est. completion 2028-08-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Adult, Newly DiagnosedView official trial listing → -
Recruiting NCT NCT06536010
Clinical Trial Protocol for the Combined Use of VAG in the Treatment of ND-AML
Not yet reported Yang Xiaotian 50 participants Est. completion 2028-07-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06536959
VA Combined With PD-1 Inhibitor for the Treatment of Relapsed and Refractory AML and High-risk MDS
Not yet reported Beijing 302 Hospital 67 participants Est. completion 2027-07-31 1 site Stand-aloneOther conditions: Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Myelodysplastic Syndromes, Minimal Residual DiseaseView official trial listing → -
Recruiting NCT NCT06537843
Safety and Efficacy of Venetoclax, Cytarabine and Metformin (VenCM) for Relapsed-Refractory and Induction-Ineligible Acute Myeloid Leukemia
Not yet reported Hospital Municipal São José 100 participants Est. completion 2028-07-01 5 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06548230
A Phase 1B/2A Trial of NADUNOLIMAB in Combination With Azacitidine (With/Without Venetoclax) in Patients With Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)
Not yet reported, Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2029-12-01 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome(MDS), Acute Myelogenous Leukemia (AML)View official trial listing → -
Recruiting NCT NCT06554626
Blinatumomab Plus Venetoclax Sequenced With Inotuzumab Ozogamicin in Treating B-ALL
Not yet reported First Affiliated Hospital of Zhejiang University 20 participants Est. completion 2027-08-01 1 site Stand-aloneOther conditions: Precursor B-Cell Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06557421
De-Escalation Study Evaluating Venetoclax and Azacitidine Discontinuation in AML Responding Patients
Not yet reported Institut Paoli-Calmettes 50 participants Est. completion 2028-11-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06558604
Phase II Study of Glofitamab With Venetoclax +/- Zanubrutinib in High-risk Mantle-cell Lymphoma
Not yet reported The Lymphoma Academic Research Organisation 100 participants Est. completion 2032-03 16 sites Stand-aloneOther conditions: Lymphoma, Mantle-CellView official trial listing → -
Recruiting NCT NCT06561074
A Phase 2 Study to Evaluate Efficacy of Calaspargase Pegol-mknl and Decitabine Combined With Venetoclax in Pediatric, Adolescent, and Young Adult Patients With Relapsed/Refractory T-cell Acute Lymphoblastic Leukemia (T-ALL) and T- Cell Lymphoblastic Lymphoma (T-LLy)
Not yet reported M.D. Anderson Cancer Center 22 participants Est. completion 2031-12-31 1 site Stand-aloneOther conditions: T-cell Acute Lymphoblastic Leukemia, T-Cell Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT06561880
The Efficacy of Triple Regimen in Newly Diagnosed AML Patients With FLT3 Mutation
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 66 participants Est. completion 2027-08-31 1 site Stand-aloneOther conditions: FLT3 Gene Mutation, AMLView official trial listing → -
Recruiting NCT NCT06571825
RIC Allo-HSCT vs. Venetoclax-Based Consolidation in Elderly AML Patients After First CR
Not yet reported He Huang 118 participants Est. completion 2028-02-28 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06580106
Toxicity Genetic Determinants and Response to Azacitidine and Venetoclax in AML
Wake Forest University Health Sciences 50 participants Est. completion 2030-01 2 sitesOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Recruiting NCT NCT06611839
Venetoclax in Combination With Ivosidenib and Azacitidine for Newly Diagnosed IDH1-Mutated AML
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 23 participants Est. completion 2028-10-01 1 site Stand-aloneOther conditions: AML, IDH1 Mutation, TreatmentView official trial listing → -
Recruiting NCT NCT06621199
Mitoxantrone Hydrochloride Liposome in Combination With Cytarabine and Venetoclax Regimen in Newly Diagnosed Elderly AML
Not yet reported First Affiliated Hospital of Zhejiang University 42 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06621212
Mitoxantrone Hydrochloride Liposome, Standard-dose of Cytarabine and Venetoclax in the Treatment of R/R AML
Not yet reported First Affiliated Hospital of Zhejiang University 72 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Relapsed/Refractory Acute Myeloid Leukaemia, Myeloid MalignancyView official trial listing → -
Recruiting NCT NCT06634394
APVO436 Phase 1b/2 Study in Patients With Newly Diagnosed AML
Not yet reported Aptevo Therapeutics 39 participants Est. completion 2028-03 7 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT06635681
Efficacy of Venetoclax Combined With Intensive Chemotherapy in Different Subgroups of AML
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 380 participants Est. completion 2028-10-01 1 site Stand-aloneOther conditions: AML (Acute Myelogenous Leukemia)View official trial listing → -
Recruiting NCT NCT06643962
Venetoclax Combined with Intensive Therapy for Acute Myeloid Leukemia Patients with Lower Early Peripheral Blast Clearance Rate After Standard Induction Therapy
Not yet reported Affiliated Hospital of Nantong University 83 participants Est. completion 2027-10-31 1 site Stand-aloneOther conditions: Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, AcuteView official trial listing → -
Recruiting NCT NCT06644183
Roginolisib (IOA-244) With Venetoclax and Rituximab for Refractory/Relapsed Chronic Lymphocytic Leukemia (CLL)
Not yet reported, Not yet reported Jennifer R. Brown, MD, PhD 64 participants Est. completion 2032-10-01 1 site Stand-aloneOther conditions: Leukemia, Relapsed Leukemia, Chronic Lymphocytic Leukemia, Relapsed Cancer, Refractory LeukemiaView official trial listing → -
Recruiting NCT NCT06649812
Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma
Not yet reported National Cancer Institute (NCI) 120 participants Est. completion 2028-09-01 114 sites Stand-aloneOther conditions: High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type, Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements, Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified, Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type, Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements, Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified, Refractory T-Cell/Histiocyte-Rich Large B-Cell LymphomaView official trial listing → -
Recruiting NCT NCT06651970
Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure
Not yet reported AstraZeneca 60 participants Est. completion 2032-09-30 23 sitesOther conditions: Chronic Lymphocytic Leukaemia, Moderate to Severe Cardiac ImpairmentView official trial listing → -
Recruiting NCT NCT06652438
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
Not yet reported Stichting Hemato-Oncologie voor Volwassenen Nederland 448 participants Est. completion 2032-08-27 201 sitesOther conditions: Acute Myeloid Leukemia, AdultView official trial listing → -
Recruiting NCT NCT06660368
BCL2i CLAG-M in R/R Acute Myeloid Leukemia
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 52 participants Est. completion 2027-11 2 sites Stand-aloneOther conditions: Relapsed or Refractory Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT06672146
Comparing New Treatments for People With Newly Diagnosed Acute Myeloid Leukemia That Has an IDH2 Gene Change (A MyeloMATCH Treatment Trial)
Not yet reported National Cancer Institute (NCI) 93 participants Est. completion 2027-03-31 138 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06686108
Demethylating Agents Combined With Venetoclax for High-risk T-cell Lymphoblastic Lymphoma/Leukemia Post-Transplant Relapse Prevention
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 59 participants Est. completion 2028-10-30 1 site Stand-aloneOther conditions: T-cell Acute Lymphoblastic Leukemia, ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, RelapseView official trial listing → -
Recruiting NCT NCT06696183
Gilteritinib in Combination With Venetoclax and Azacitidine for AML Patients With FLT3 Mutations Ineligible for Intensive Treatment
Not yet reported Technische Universität Dresden 60 participants Est. completion 2030-04 1 site Stand-aloneOther conditions: AML - Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06708897
A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies
Not yet reported Lomond Therapeutics Holdings, Inc. 84 participants Est. completion 2028-07 5 sites Stand-aloneOther conditions: CLL / SLL, CLL (Chronic Lymphocytic Leukemia), SLL (Small Lymphocytic Lymphoma), Marginal Zone Lymphoma(MZL), Lymphoplasmacytic Lymphoma/Waldenström MacroglobulinemiaView official trial listing → -
Recruiting NCT NCT06712121
Venetoclax and Decitabine in R/R T-ALL
Not yet reported Seoul National University Hospital 28 participants Est. completion 2028-08-31 3 sites Stand-aloneOther conditions: T Lymphoblastic Leukemia/LymphomaView official trial listing → -
Recruiting NCT NCT06713837
IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.
Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 339 participants Est. completion 2028-01 51 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Relapse/RecurrenceView official trial listing → -
Recruiting NCT NCT06737523
Chiglitazar Sodium Combined With Venetoclax and Azacitidine (CVA) for the Treatment of R/R AML
Not yet reported The First Affiliated Hospital of Xiamen University 30 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Relapse, Refractory AMLView official trial listing → -
Recruiting NCT NCT06742463
VHAG in Treating R/R T-ALL/LBL
Not yet reported First Affiliated Hospital of Zhejiang University 50 participants Est. completion 2028-06-30 1 site Stand-aloneOther conditions: Acute T Lymphpblastic Leukemia/LymphomaView official trial listing → -
Recruiting NCT NCT06742515
Blinatumomab Plus Reduced-dose Chemotherapy in Treating B-ALL
Not yet reported First Affiliated Hospital of Zhejiang University 20 participants Est. completion 2028-08-31 1 site Stand-aloneOther conditions: Precursor B-Cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06746519
BN104 in Combination With Chemotherapy or Targeted Agents for Acute Myeloid Leukemia
Not yet reported, Not yet reported Chen Suning 135 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06754267
Venetoclax Combined With Olverembatinib and Predinisone in Treating Ph+ B-ALL
Not yet reported First Affiliated Hospital of Zhejiang University 36 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Precursor B-Cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06757855
Olverembatinib Combined With Venetoclax and Azacitidine in Blast Phase Ph Chromosome-positive CML
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 29 participants Est. completion 2028-12-01 1 siteOther conditions: CML,Blast PhaseView official trial listing → -
Recruiting NCT NCT06763341
A Phase 1 Study of AOH1996 in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported City of Hope Medical Center 12 participants Est. completion 2027-01-16 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06764238
Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 1800 participants Est. completion 2031-06 27 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia ALL, Childhood Leukemia, Acute Lymphoblastic, B Cell Acute Lymphoblastic Leukemia (B-ALL)View official trial listing → -
Recruiting NCT NCT06773208
A Study of Azacitidine and Venetoclax in People With Acute Myeloid Leukemia (AML)
Not yet reported Memorial Sloan Kettering Cancer Center 30 participants Est. completion 2027-01 7 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT06778187
Oral-ATO for TP53-mutated Myeloid Malignancies
Not yet reported The University of Hong Kong 30 participants Est. completion 2028-02 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Neoplasm, Chronic Myelomonocytic Leukemia, TP53 Gene Mutation, Arsenic TrioxideView official trial listing → -
Recruiting NCT NCT06782542
Olutasidenib, Venetoclax, and Azacitidine in IDH1 Mutated Newly Diagnosed Acute Myeloid Leukemia Patients Eligible for Intensive Induction Chemotherapy
Not yet reported Justin Watts, MD 16 participants Est. completion 2029-03-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, IDH1 MutationView official trial listing → -
Recruiting NCT NCT06782971
Evaluation of Combined Sensitising and Hypomethylating Therapy Outcomes in AML PDX
Clinical Hub for Interventional Research (CHOIR) 25 participants Est. completion 2030-03 4 sitesOther conditions: AML - Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06783790
Avapritinib Combined With Azacitidine and Venetoclax in the Treatment of Relapsed AML After Allo-HSCT
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 20 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: AML (Acute Myelogenous Leukemia)View official trial listing → -
Recruiting NCT NCT06810778
Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)
Not yet reported, Not yet reported Jonsson Comprehensive Cancer Center 12 participants Est. completion 2031-06-01 1 site Stand-aloneOther conditions: T-cell-prolymphocytic Leukemia, Cutaneous T-Cell Lymphoma RefractoryView official trial listing → -
Recruiting NCT NCT06810791
HVA vs IA/DA or VA in the Treatment of ND HR-AML
Not yet reported Nanfang Hospital, Southern Medical University 876 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Newly Diagnosed Acute Myeloid Leukemia With High RiskView official trial listing → -
Recruiting NCT NCT06846671
A Study of Tacabrutideg (BGB-16673) Compared to Investigator's Choice in Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Previously Exposed to Both Bruton Tyrosine Kinase (BTK) and B-cell Leukemia/Lymphoma 2 Protein (BCL2) Inhibitors
Not yet reported BeOne Medicines 250 participants Est. completion 2030-02-14 132 sitesOther conditions: CLL, Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT06852222
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Not yet reported Janssen Research & Development, LLC 600 participants Est. completion 2029-08-15 266 sites Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Recruiting NCT NCT06855810
Newly-diagnosed Pediatric T-cell ALL Protocol
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 610 participants Est. completion 2031-06 27 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Childhood Leukemia, Acute Lymphoblastic, T Cell Acute Lymphoblastic Leukemia/Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT06863259
Study of Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone for Relapsed B-cell ALL
Not yet reported Children's Hospital Medical Center, Cincinnati 28 participants Est. completion 2029-01-01 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06874257
Targeting Acute Myeloid Leukemia Immunosuppressive Microenvironment by combinedIDO1 Inhibition and PD-1 Blockade
IRCCS Azienda Ospedaliero-Universitaria di Bologna 20 participants Est. completion 2026-10-31 1 siteOther conditions: AML (Acute Myelogenous Leukemia)View official trial listing → -
Recruiting NCT NCT06917911
Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)
Not yet reported National Cancer Institute (NCI) 162 participants Est. completion 2027-11-25 80 sites Stand-aloneOther conditions: Core Binding Factor Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06918834
Efficacy of Immediate Allogeneic Hematopoietic Stem Cell Transplantation Versus Bridging Therapy Followed by Transplantation in Higher-Risk Myelodysplastic Syndrome Patients
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 236 participants Est. completion 2028-04-01 5 sitesOther conditions: Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT06928376
A Multicenter RCT of "3+7" vs Venetoclax + CACAG in Newly Diagnosed Mid/High-Risk AML Patients
Not yet reported Chinese PLA General Hospital 160 participants Est. completion 2026-09-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, First Line TherapyView official trial listing → -
Recruiting NCT NCT06943872
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Not yet reported BeOne Medicines 630 participants Est. completion 2031-12 195 sitesOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT06958705
Venetoclax as Consolidation in CLL Patients Treated With BTK Inhibitor Monotherapy
Not yet reported The First Affiliated Hospital with Nanjing Medical University 79 participants Est. completion 2028-02-01 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL) / Small Lymphocytic Lymphoma (SLL)View official trial listing → -
Recruiting NCT NCT06967610
Phase II Study of Combined Pirtobrutinib, Venetoclax and Obinutuzumab (PVO) Time-limited Treatment for Patients With Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL).
Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2033-06-01 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia (SLL)View official trial listing → -
Recruiting NCT NCT06972641
Molecular Genetics Guide the Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported, Not yet reported Ruijin Hospital 126 participants Est. completion 2030-03-31 1 site Stand-aloneOther conditions: AML, MDSView official trial listing → -
Recruiting NCT NCT06990321
Effectiveness of Medium-Dose Cytarabine Combined With Venetoclax for Consolidation Therapy in Elderly Patients With Intermediate to High-Risk Acute Myeloid Leukemia
Not yet reported Yehui Tan 68 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), ElderlyView official trial listing → -
Recruiting NCT NCT07007052
Phase II Study Evaluating the Efficacy and Safety of the Combination of Tagraxofusp and Venetoclax in Treatment-naive Blastic Plasmacytoid Dendritic Cell Neoplasm Patients
Not yet reported French Innovative Leukemia Organisation 33 participants Est. completion 2031-10-02 34 sites Stand-aloneOther conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)View official trial listing → -
Recruiting NCT NCT07007312
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
Not yet reported Kura Oncology, Inc. 1300 participants Est. completion 2031-11 136 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT07007949
a New Treatment of Newly Diagnosed IDH1 Mutation Acute Myeloid Leukemia
Not yet reported The First Affiliated Hospital of Soochow University 42 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, IDH1 Gene Mutation, IvosidenibView official trial listing → -
Recruiting NCT NCT07012447
Venetoclax + Azacytidine for Newly Diagnosed ETP-like ALL and T-ALL With Myeloid Mutations
Not yet reported yuejun Liu 32 participants Est. completion 2028-05-01 1 site Stand-aloneOther conditions: Early T Acute Lymphoblastic Leukemia, T-Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia, T/Myeloid, NosView official trial listing → -
Recruiting NCT NCT07014917
Intermittent Versus Continuous Venetoclax With Acalabrutinib for CLL/SLL
Not yet reported Zulfa Omer 62 participants Est. completion 2032-06-05 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, CLL VariantView official trial listing → -
Recruiting NCT NCT07023588
Study on Optimizing the Treatment of Patients With Acute Myeloid Leukemia Based on Early Peripheral Blood Minimal Residual Disease
Not yet reported Yehui Tan 70 participants Est. completion 2029-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT07024706
MAVRiC Studies 2L Treatment With AV in Patients With CLL/SLL Who Have Relapsed After a Course of BTKi + BCL2i Combination, With or Without Obinutuzumab
Not yet reported AstraZeneca 80 participants Est. completion 2033-03-23 47 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)View official trial listing → -
Recruiting NCT NCT07028073
A New Treatment of Newly Diagnosed KIT Mutation CBF-Acute Myeloid Leukemia
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 78 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia With T(8;21)(Q22;Q22), Acute Myeloid Leukemia With T(16;16)(P13;Q22), KIT Gene Mutation, AvapritinibView official trial listing → -
Recruiting NCT NCT07028086
VAM in Secondary AML, AML With Extramedullary Involvement, and Myeloid Sarcoma
Not yet reported Ruijin Hospital 48 participants Est. completion 2028-04 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myeloid SarcomaView official trial listing → -
Recruiting NCT NCT07032727
Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations
Not yet reported M.D. Anderson Cancer Center 68 participants Est. completion 2029-06-01 2 sites Stand-aloneOther conditions: Targeted Therapy, IDH1-Mutated Malignancies, MutationsView official trial listing → -
Recruiting NCT NCT07039877
Efficacy of Low-dose Venetoclax With Itraconazole + TACL for R/R ALL Patients
Not yet reported Hospital Universitario Dr. Jose E. Gonzalez 12 participants Est. completion 2026-04-30 1 site Stand-aloneOther conditions: Acute Lymphobkastic Leukemia, Acute Lymphoblastic Leukaemia Recurrent, Philadelphia Chromosome Negative ALLView official trial listing → -
Recruiting NCT NCT07044544
Trial of Novel Anti-leukemia Agents in Flu/Mel RIC Transplant for Myeloid Malignancies
Not yet reported University of Alabama at Birmingham 20 participants Est. completion 2027-01 1 site Stand-aloneOther conditions: Myeloid Malignancy, Hematologic Malignancy, Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT07044687
Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in India
Not yet reported AbbVie 100 participants Est. completion 2027-11 14 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07047183
Clinical Study of Venetoclax Combined With Azacitidine as Bridging Therapy Prior to Hematopoietic Stem Cell Transplantation in Patients With Higher-Risk Myelodysplastic Syndromes
Not yet reported Yehui Tan 46 participants Est. completion 2029-06-30 1 site Stand-aloneOther conditions: Myelodysplastic Neoplasms, TransplantationView official trial listing → -
Recruiting NCT NCT07059156
Multicenter Study of Combined Chemotherapy and Transplantation for Adult ALL
Not yet reported, Not yet reported Shanxi Bethune Hospital 50 participants Est. completion 2027-07 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, AdultView official trial listing → -
Recruiting NCT NCT07059975
UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML
Not yet reported Baylor College of Medicine 36 participants Est. completion 2031-08 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Pediatric AMLView official trial listing → -
Recruiting NCT NCT07060001
Efficacy of Hypomethylating Agents vs. Intensive Chemotherapy in Acute Myeloid Leukemia Using 5hmC as a Blood-Based Minimal Residual Disease Marker
Not yet reported The Methodist Hospital Research Institute 112 participants Est. completion 2029-12 1 siteOther conditions: Acute Myeloid Leukemia (AML), Acute Myeloid Leukaemia (AML)View official trial listing → -
Recruiting NCT NCT07075016
Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy
Not yet reported Stichting Hemato-Oncologie voor Volwassenen Nederland 227 participants Est. completion 2029-03 119 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07078591
Venetoclax-containing Therapy Combined With Microtransplant for Newly Diagnosed AML
Not yet reported Beijing 302 Hospital 50 participants Est. completion 2031-06 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07108530
Efficacy of Integrated Induction-Consolidation Chemotherapy and Transplantation for Adult Acute Myeloid Leukemia: Multicenter Study
Not yet reported Shanxi Bethune Hospital 50 participants Est. completion 2027-08-06 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07117422
Venetoclax-Decitabine in Untreated Elderly/Unfit AML
Not yet reported The Second Hospital of Hebei Medical University 39 participants Est. completion 2027-01-30 1 site Stand-aloneOther conditions: AML, AdultView official trial listing → -
Recruiting NCT NCT07131059
MRD-positive AML Clinical Study
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 537 participants Est. completion 2028-10-30 1 site Stand-aloneOther conditions: AML, AdultView official trial listing → -
Recruiting NCT NCT07132684
Comparison of VA and D/IA Induction Regimens in Elderly Fit Acute Myeloid Leukemia Patients
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 228 participants Est. completion 2028-08-30 1 site Stand-aloneOther conditions: AML, AdultView official trial listing → -
Recruiting NCT NCT07133997
Recombinant Erwinia Asparaginase and Venetoclax in Combination With Blinatumomab for the Treatment of Relapsed or Refractory CD19 Positive B-cell Acute Lymphoblastic Leukemia
Not yet reported City of Hope Medical Center 26 participants Est. completion 2028-06-01 1 site Stand-aloneOther conditions: Recurrent B Acute Lymphoblastic Leukemia, Refractory B Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT07148180
A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax
Not yet reported, Not yet reported Jacqueline Garcia, MD 31 participants Est. completion 2030-12-31 2 sites Stand-aloneOther conditions: Acute Myeloid Leukaemia (AML), Leukemia, Blood Cancer, Blood CancersView official trial listing → -
Recruiting NCT NCT07152041
Newly-diagnosed Pediatric Ph-positive B-ALL Protocol
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 150 participants Est. completion 2030-06 24 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+), Childhood Leukemia, Acute LymphoblasticView official trial listing → -
Recruiting NCT NCT07154264
A Study of DZD8586 Combination in CLL/SLL (TAI-SHAN10)
Not yet reported Dizal Pharmaceuticals 66 participants Est. completion 2030-01 15 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT07159620
Venetoclax Combined With Azacitidine, Chidamide, Vindesine, and Dexamethasone in Newly Diagnosed ETP-ALL Like Patients
Not yet reported The First Affiliated Hospital of Soochow University 27 participants Est. completion 2030-09-01 1 site Stand-aloneOther conditions: Adult T-cell Leukemia/LymphomaView official trial listing → -
Recruiting NCT NCT07172204
Alternating Regimen of VA and Low-dose CHA in the Treatment of Unfit Newly Diagnosed AML
Not yet reported First Affiliated Hospital of Zhejiang University 25 participants Est. completion 2029-07-31 5 sites Stand-aloneOther conditions: Intensive Chemotherapy Unfit, Newly Diagnosed Acute Myeloid Leukemia (AML), Age ≥60View official trial listing → -
Recruiting NCT NCT07177079
High-dose Ascorbate (HDA) in Combination With Standard of Care Azacitidine and Venetoclax in Acute Myeloid Leukemia (AML)
Not yet reported Kittika Poonsombudlert 30 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07183878
Venetoclax-Enhanced BUCY vs. Standard BUCY Conditioning in High-Risk AML and MDS Patients Undergoing Allo-HSCT (Ven-BUCY Study)
Not yet reported First Affiliated Hospital of Zhejiang University 138 participants Est. completion 2028-08-20 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndromes, High-Risk Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT07218510
Venetoclax and Obinutuzumab Followed by Epcoritamab for the Treatment of Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, LonGEVity Trial
Not yet reported City of Hope Medical Center 33 participants Est. completion 2029-06-08 7 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT07228273
Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia
Not yet reported OHSU Knight Cancer Institute 102 participants Est. completion 2029-08-24 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT07231952
A Study of Pirtobrutinib, Venetoclax, and Rituximab in People With Waldenström's Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)
Not yet reported Memorial Sloan Kettering Cancer Center 40 participants Est. completion 2028-04-11 9 sites Stand-aloneOther conditions: Waldenstrom Macroglobulinemia, Lymphoplasmacytic LymphomaView official trial listing → -
Recruiting NCT NCT07238686
Venetoclax-containing Therapy Combined With Microtransplant for Intermediate-risk and Higher MDS
Not yet reported Beijing 302 Hospital 40 participants Est. completion 2031-06 1 site Stand-aloneOther conditions: Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT07243483
Study of the Relationship Between the Pharmacokinetics (PK) and Pharmacodynamics of Venetoclax in Patients With Acute Myeloblastic Leukemia
Not yet reported Centre Leon Berard 100 participants Est. completion 2029-01-01 5 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07244367
Maintenance Venetoclax in AML Fit Patients
Not yet reported Sohag University 80 participants Est. completion 2027-09-01 2 sitesOther conditions: Acute Myeloid Leukaemia (AML)View official trial listing → -
Recruiting NCT NCT07254312
Correlation of Venetoclax Plasma Concentrations With Toxicity of Hypometilating Agents and Venetoclax Combination for Acute Myeloid Leukemia Patients in Remission.
Fondazione IRCCS Policlinico San Matteo di Pavia 14 participants Est. completion 2026-04 1 siteOther conditions: AML (Acute Myelogenous LeukemiaView official trial listing → -
Recruiting NCT NCT07255872
A Study of BL-M11D1 in Combination With Cytarabine + Daunorubicin or Venetoclax + Azacitidine in Patients With Acute Myeloid Leukemia
Not yet reported, Not yet reported Sichuan Baili Pharmaceutical Co., Ltd. 216 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07259707
Gilteritinib Plus VA Followed By Consolidation Chemotherapy in Newly Diagnosed FLT3-ITD+ AML
Not yet reported First Affiliated Hospital of Zhejiang University 25 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, FLT3 Internal Tandem Duplication Positive, Intermediate Risk Acute Myeloid Leukemia, Fit PatientsView official trial listing → -
Recruiting NCT NCT07270978
Phase Ib Study of CD33 FPBMC in Patients With MRD+ AML or MDS
Not yet reported University of Virginia 23 participants Est. completion 2031-07 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmView official trial listing → -
Recruiting NCT NCT07277231
A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia
Not yet reported BeOne Medicines 500 participants Est. completion 2031-11 115 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT07283094
FHD-286 With Low-Dose Weekly Decitabine/Venetoclax in Patients With Acute Myeloid Leukemia
Not yet reported Montefiore Medical Center 33 participants Est. completion 2030-02 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT07294677
CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL
Not yet reported, Not yet reported University of Chicago 104 participants Est. completion 2032-03 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Recruiting NCT NCT07297173
Phase 1 Study of Chemotherapy Plus HLA-mismatched GPBMC Infusion Bridging to Allo-HSCT for R/R Leukemia
Not yet reported Beijing 302 Hospital 5 participants Est. completion 2030-12-01 1 site Stand-aloneOther conditions: Relapsed Leukemia, Refractory LeukemiaView official trial listing → -
Recruiting NCT NCT07304011
Olutasidenib With Azacitidine Followed by Olutasidenib Maintenance for the Treatment of IDH1-mutated Acute Myeloid Leukemia in Patients With Prior Treatment With Venetoclax Plus a Hypomethylating Agent
Not yet reported University of California, Davis 28 participants Est. completion 2029-12-01 2 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07311746
Phase Ib/II Trial of Cladribine/Ruxolitinib/Venetoclax in Patients With Relapsed/Refractory T-cell Prolymphocytic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 36 participants Est. completion 2031-01-31 1 site Stand-aloneOther conditions: T-cell Prolymphocytic Leukemia, Refractory T-Cell Prolymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT07320235
Imetelstat Combinations in Relapsed AML
Not yet reported Douglas Tremblay 36 participants Est. completion 2035-06-15 1 siteOther conditions: Relapsed Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07358195
Addition of Venetoclax to Combined Hematopoietic Stem Cell and Kidney Transplantation
Not yet reported Massachusetts General Hospital 3 participants Est. completion 2031-12 1 site Stand-aloneOther conditions: Kidney Failure Chronic, Stem Cell Transplant, Stem Cell Transplant Complications, Tolerance, Hematologic CancerView official trial listing → -
Recruiting NCT NCT07374029
Adoptive T Cell Therapy With DC/AML Fusion Vaccine Plus Decitabine and Venetoclax in AML
Not yet reported David Avigan 30 participants Est. completion 2030-10-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia, in RelapseView official trial listing → -
Recruiting NCT NCT07392242
A Study of the Combination of Ivosidenib, Azacitidine, and Venetoclax Followed by Ivosidenib Alone in People With Acute Myeloid Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 45 participants Est. completion 2028-01 7 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07396480
Fludarabine Plus Melphalan Versus Addition of Venetoclax to Fludarabine/Melphalan Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in AML/MDS Patients Aged > 50 Years: a Multicenter, Randomized, Phase 3 Trial
Not yet reported First Affiliated Hospital of Zhejiang University 186 participants Est. completion 2030-06-30 18 sites Stand-aloneOther conditions: Venentoclax, Myeloid Malignancies, Conditioning, ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Acute Myeloid Leucemia, Myeldysplastic Syndrome (MDS)View official trial listing → -
Recruiting NCT NCT07420790
Design and Validation of a Generative AI and Propensity Score Matching Model for the VEN-DEC Phase II Study in Elderly AML Eligible for Allo-SCT; Evaluation of an Exploratory Approach Respect to a Randomized Phase III Trial
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 1941 participants Est. completion 2026-12 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07425782
Venetoclax Combined With Azacitidine for Consolidation Therapy in AML
Not yet reported The First Affiliated Hospital of Soochow University 216 participants Est. completion 2028-11-26 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Consolidation Therapy, Venentoclax, High Risk, Hematopoietic Stem Cell Transplant (HSCT)View official trial listing → -
Recruiting NCT NCT07437950
Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
Not yet reported National Cancer Institute (NCI) 126 participants Est. completion 2034-09-22 46 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07439211
Assessing PI3K Gamma Inhibition With Azacitidine, Venetoclax and Eganelisib in Patients With Acute Myeloid Leukemia
Not yet reported Jacqueline Garcia, MD 48 participants Est. completion 2029-02-01 2 sites Stand-aloneOther conditions: Leukemia, Myeloid, Leukemia, Acute Myeloid Leukemia, Refractory LeukemiaView official trial listing → -
Recruiting NCT NCT07451912
Venetoclax Plus Hypomethylating Agents and Subcutaneous Cytarabine for CEBPA-Mutated AML
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 29 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), CEBPA Mutation, Unfit, New-diagnosis AMLView official trial listing → -
Recruiting NCT NCT07454226
ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 92 participants Est. completion 2030-03-01 1 site Stand-aloneOther conditions: Ph-Like, Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT07471841
Olutasidenib in Relapsed IDH1 Mutated AML Patients Who Have Previously Received Venetoclax
Not yet reported Timothy Pardee 25 participants Est. completion 2029-06 1 siteOther conditions: IDH1 Mutation, Relapsed / Refractory AMLView official trial listing → -
Recruiting NCT NCT07478991
Azacytidine, Venetoclax Plus Minus Quizartinib for First Line Older/Unfit AML Patients (VENP-A-QUI)
Not yet reported PETHEMA Foundation 376 participants Est. completion 2030-04 52 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, AdultView official trial listing → -
Recruiting NCT NCT07481175
Inhibiting the Anti-apoptotic Factor, BCL-2, at the Time of ART Initiation to Promote Apoptosis of HIV-infected Cells and Restrict the Seeding of the HIV Reservoir (The INITIATE Study)
Not yet reported Thomas Aagaard Rasmussen 38 participants Est. completion 2030-01 2 sites Stand-aloneOther conditions: HIV-1View official trial listing → -
Recruiting NCT NCT07490288
Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 27 participants Est. completion 2029-03-01 1 site Stand-aloneOther conditions: AMLView official trial listing → -
Recruiting NCT NCT07493161
Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 110 participants Est. completion 2030-03-30 1 site Stand-aloneOther conditions: Ph+ ALLView official trial listing → -
Recruiting NCT NCT07495631
Pediatric-Inspired Regimen Combined With Venetoclax and Immunotherapy for Adult Ph-Negative Acute Lymphoblastic Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 43 participants Est. completion 2030-03-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, AdultView official trial listing → -
Recruiting NCT NCT07512700
Venetoclax Combined With CACAG Regimen Versus "3+7" Regimen in the Treatment of Acute Monocytic Leukemia
Not yet reported Chinese PLA General Hospital 204 participants Est. completion 2029-10-31 3 sites Stand-aloneOther conditions: Acute Monocytic LeukemiaView official trial listing → -
Recruiting NCT NCT07513129
Venetoclax, Dexamethasone, Bortezomib, and Daratumumab For The Treatment Of Adolescent And Young Adults With Relapsed Or Refractory T-Cell Acute Lymphoblastic Leukemia And T-cell Acute Lymphoblastic Lymphoma
Not yet reported M.D. Anderson Cancer Center 18 participants Est. completion 2031-12-31 1 site Stand-aloneOther conditions: T-cell Acute Lymphoblastic Leukemia, LymphomaView official trial listing → -
Recruiting NCT NCT07514832
VA-CIG Regimen for Previously Untreated Acute Myeloid Leukemia: A Multicenter Prospective Single-Arm Trial
Not yet reported Beijing 302 Hospital 48 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: AML (Acute Myeloid Leukemia)View official trial listing → -
Recruiting NCT NCT07514936
Venetoclax-Azacitidine in Combination With Chidamide and CAG in Fit Older Patients With Acute Myeloid Leukaemia
Not yet reported Chinese PLA General Hospital 120 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Newly Diagnosed Acute Myeloid Leukemia (AML), Elderly PatientsView official trial listing → -
Recruiting NCT NCT07520006
Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies
Not yet reported, Not yet reported Nurix Therapeutics, Inc. 150 participants Est. completion 2033-05 6 sites Stand-aloneOther conditions: B-cell Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT07539818
Azacitidine + Venetoclax VS Azacitidineas Maintenance Therapy in AML
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 788 participants Est. completion 2031-04-01 1 site Stand-aloneOther conditions: AMLView official trial listing → -
Recruiting NCT NCT07557056
Nemtabrutinib and Venetoclax for the Treatment of Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported Jennifer Woyach 25 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT07563179
Bugitinib Combined With Venetoclax and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Shenzhen University General Hospital 10 participants Est. completion 2029-06-30 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Relapse/RecurrenceView official trial listing → -
Recruiting NCT NCT07581002
A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)
Not yet reported, Not yet reported AbbVie 660 participants Est. completion 2032-06 38 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07583888
VABu Conditioning in Elderly AML HSCT
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 20 participants Est. completion 2027-08-15 1 site Stand-aloneOther conditions: Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT07602088
A Real-world Study of Ibrutinib and Venetoclax (I+V) First-Line Treatment Given for Fixed-duration of Time in Participants With Chronic Lymphocytic Leukemia
Janssen Research & Development, LLC 60 participants Est. completion 2029-11-30 1 siteOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Recruiting NCT NCT07617285
Allogeneic CAR-T(CT0890B) in NKG2DL+ R/R AML
Not yet reported Peking University People's Hospital 27 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: AML, Refractory/Relapse Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07670130
Venetoclax TDM in Newly Diagnosed AML: Exposure-Response and Prognosis
The First Affiliated Hospital of Soochow University 50 participants Est. completion 2027-06-01 1 siteOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT07672262
VA Consolidation in Intermediate-Risk AML
Not yet reported The First Affiliated Hospital of Soochow University 226 participants Est. completion 2030-06-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Intermediate Risk Acute Myeloid Leukemia, Consolidation TherapyView official trial listing → -
Recruiting NCT NCT07691047
Reassessment of the Risk of Hemolytic Syndrome in Patients With Chronic Lymphocytic Leukemia Treated With a Regimen Containing Venetoclax
Not yet reported Private Hospital of Confluent, France 130 participants Est. completion 2029-09-30 2 sitesOther conditions: Chronic Lymphoid LeukemiaView official trial listing → -
Recruiting NCT NCT07710534
Metronomic Decitabine-Cedazuridine and Venetoclax in R/R AML, HR-MDS, HR/AP MPN
Not yet reported Virginia Commonwealth University 40 participants Est. completion 2033-12-31 1 site Stand-aloneOther conditions: Relapsed / Refractory AML, High Risk Myelodysplastic Syndrome, High Risk Myeloproliferative NeoplasmsView official trial listing → -
Recruiting NCT NCT07712848
DEC3-VEN vs. Venetoclax-Based vs. DA Regimens in Newly Diagnosed AML
Not yet reported The Second Affiliated Hospital of Kunming Medical University 291 participants Est. completion 2027-12-01 1 site Stand-aloneOther conditions: AML (Acute Myeloid Leukemia)View official trial listing → -
Recruiting NCT NCT07713732
TLN-499 in Combination With Venetoclax in Patients With Relapsed/Refractory Solid Tumors
Not yet reported Treeline Biosciences, Inc. 120 participants Est. completion 2030-08-29 3 sites Stand-aloneOther conditions: Small Cell Lung Cancer ( SCLC ), Neuroendocrine Cancer, Malignant Pleural Mesotheliomas (Mpm), Synovial SarcomasView official trial listing → -
Recruiting NCT NCT07719556
Orelabrutinib Combined With Obinutuzumab and Short-Course Venetoclax in Patients With Treatment-Naïve Mantle Cell Lymphoma (MCL)
Not yet reported The First Affiliated Hospital with Nanjing Medical University 39 participants Est. completion 2029-07-01 2 sites Stand-aloneOther conditions: Mantle Cell Lymphoma (MCL)View official trial listing → -
Recruiting NCT NCT07734038
Venetoclax Plus Zanubrutinib for the Treatment of Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
Not yet reported Kerry Rogers 155 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT07743112
A Phase 2 Study of MAX-40279 Combined With Venetoclax and Azacitidine in Unfit Newly Diagnosed Acute Myeloid Leukemia
Not yet reported Maxinovel Pty., Ltd. 43 participants Est. completion 2027-12-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07774390
Ibrutinib Plus Venetoclax Long-Term Outcomes in CLL
European Research Initiative on CLL 323 participants Est. completion 2034-11-20 1 siteOther conditions: Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)View official trial listing → -
Recruiting NCT NCT07783100
Venetoclax, Chidamide, and Chiglitazar Sodium (VCC) in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported The First Affiliated Hospital of Xiamen University 30 participants Est. completion 2028-11-30 1 site Stand-aloneOther conditions: Relapsed or Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07874100
This Study Aims to Improve the Stratification of Patients With Acute Myeloid Leukemia to Enable More Personalized and Effective Treatments, and to Identify and Functionally Validate, at the Single-cell Level, Biomarkers That Can Predict Response to Venetoclax.
Not yet reported Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 420 participants Est. completion 2030-12 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT01211457
Study of Sapacitabine in Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS)
Not yet reported, Not yet reported Cyclacel Pharmaceuticals, Inc. 65 participants Est. completion 2020-12-31 3 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT01328626
A Phase 1 Study Evaluating the Safety and Pharmacokinetics of ABT-199 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia and Non-Hodgkin Lymphoma
Not yet reported AbbVie 222 participants Est. completion 2020-05-08 10 sitesOther conditions: Chronic Lymphocytic Leukemia, Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT01594229
A Study Evaluating the Safety and Pharmacokinetics of ABT-199 in Combination With Bendamustine/Rituximab (BR) in Subjects With Relapsed or Refractory Non-Hodgkin's Lymphoma
Not yet reported AbbVie 60 participants Est. completion 2020-07-14 8 sitesOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT01671904
A Study of Venetoclax in Combination With Bendamustine + Rituximab or Bendamustine + Obinutuzumab in Participants With Relapsed/Refractory or Previously Untreated Chronic Lymphocytic Leukemia (CLL)
Not yet reported Genentech, Inc. 84 participants Est. completion 2020-08-11 12 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT01682616
A Phase 1b Study Evaluating the Safety and Tolerability of ABT-199 in Combination With Rituximab in Subjects With Relapsed Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
Not yet reported AbbVie 49 participants Est. completion 2022-06-23 6 sitesOther conditions: Small Lymphocytic Lymphoma, Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT01685892
A Study of Venetoclax in Combination With Obinutuzumab in Participants With Chronic Lymphocytic Leukemia
Not yet reported Genentech, Inc. 82 participants Est. completion 2019-08-23 10 sites Stand-aloneOther conditions: Lymphocytic Leukemia, ChronicView official trial listing → -
Completed NCT NCT01686555
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of ABT-199 in Female Patients With Systemic Lupus Erythematosus (SLE)
Not yet reported AbbVie (prior sponsor, Abbott) 97 participants Est. completion 2015-06 15 sitesOther conditions: Lupus ErythematosusView official trial listing → -
Completed NCT NCT01742988
Study to Assess the Safety, Tolerability and Pharmacokinetics of Fimepinostat (CUDC-907) in Patients With Lymphoma
Not yet reported Curis, Inc. 106 participants Est. completion 2020-10-09 11 sites Stand-aloneOther conditions: Lymphoma, Relapsed Lymphoma, Refractory Lymphoma, Relapsed and/or Refractory Lymphoma, Relapsed Ddiffuse Large B-Cell Lymphoma (DLBCL), Refractory Diffuse Large B-Cell Lymphoma (DLBCL), Relapsed and/or Refractory Diffuse Large B-Cell Lymphoma (DLBCL), Double-hit Lymphoma (DHL), Triple-hit Lymphoma (THL), Double-expressor Lymphoma (DEL), High-grade B-cell Lymphoma (HGBL)View official trial listing → -
Completed NCT NCT01794507
A Study Evaluating ABT-199 in Multiple Myeloma Subjects Who Are Receiving Bortezomib and Dexamethasone as Standard Therapy
Not yet reported AbbVie 66 participants Est. completion 2019-07-16 9 sitesOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Completed NCT NCT01794520
Study Evaluating ABT-199 in Participants With Relapsed or Refractory Multiple Myeloma
Not yet reported, Not yet reported AbbVie 117 participants Est. completion 2021-11-29 29 sites Stand-aloneOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Completed NCT NCT01889186
A Study of the Efficacy of ABT-199 in Subjects With Relapsed/Refractory or Previously Untreated Chronic Lymphocytic Leukemia With the 17p Deletion
Not yet reported AbbVie 158 participants Est. completion 2020-12-15 48 sitesOther conditions: Chronic Lymphocytic Leukemia, 17p Deletion, Cancer of the Blood and Bone MarrowView official trial listing → -
Completed NCT NCT01969669
A Study to Assess the Effect of Ketoconazole on the Metabolism of ABT-199
Not yet reported AbbVie 12 participants Est. completion 2014-09 3 sitesOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Withdrawn NCT NCT01969682
A Study to Assess the Effect of Rifampin on the Metabolism of ABT-199
Not yet reported AbbVie Est. completion 2014-05 1 siteOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT01969695
An Extension Study of ABT-199 in Subjects With Advanced Non-Hodgkin's Lymphoma
Not yet reported AbbVie 11 participants Est. completion 2019-12-16 3 sitesOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT01994837
A Phase 2 Study of ABT-199 in Subjects With Acute Myelogenous Leukemia (AML)
Not yet reported AbbVie 32 participants Est. completion 2014-12 Stand-aloneOther conditions: Acute Myelogenous Leukemia, AML, Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02005471
A Study to Evaluate the Benefit of Venetoclax Plus Rituximab Compared With Bendamustine Plus Rituximab in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
Not yet reported Hoffmann-La Roche 389 participants Est. completion 2022-08-03 111 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT02055820
A Study Evaluating the Safety, Efficacy and Pharmacokinetics of Venetoclax Combined With Chemotherapy in Participants With B-Cell Non-Hodgkin's Lymphoma (NHL) and DLBCL
Not yet reported, Not yet reported Hoffmann-La Roche 267 participants Est. completion 2019-06-28 52 sites Stand-aloneOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Withdrawn NCT NCT02095574
A Pharmacokinetic Study to Access How the Body Absorbs and Removes ABT-199 in Adults With Non-Hodgkin's Lymphoma
Not yet reported AbbVie Est. completion 2015-01Other conditions: Relapsed/Refractory Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT02141282
A Phase 2 Open-Label Study of the Efficacy and Safety of ABT-199 (GDC-0199) in Chronic Lymphocytic Leukemia (CLL) Subjects With Relapse or Refractory to B-Cell Receptor Signaling Pathway Inhibitor Therapy
Not yet reported AbbVie 127 participants Est. completion 2021-12-22 15 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT02187861
A Study Evaluating the Safety and Efficacy of Venetoclax (GDC-0199) Plus Bendamustine + Rituximab (BR) in Comparison With BR or Venetoclax Plus Rituximab in Participants With Relapsed and Refractory Follicular Non-Hodgkin's Lymphoma (fNHL)
Not yet reported Hoffmann-La Roche 163 participants Est. completion 2018-03-16 71 sites Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Terminated NCT NCT02203773
Study of ABT-199 (GDC-0199) in Combination With Azacitidine or Decitabine (Chemo Combo) in Subjects With Acute Myelogenous Leukemia (AML)
Not yet reported AbbVie 212 participants Est. completion 2022-06-16 23 sitesOther conditions: Acute Myelogenous Leukemia, Myelogenous Leukemia, Treatment Naive AMLView official trial listing → -
Completed NCT NCT02242942
Comparison of the Treatments of Obinutuzumab + Venetoclax Versus Obinutuzumab + Chlorambucil in Patients With Chronic Lymphocytic Leukemia
Not yet reported Hoffmann-La Roche 445 participants Est. completion 2025-08-27 122 sites Stand-aloneOther conditions: Lymphocytic Leukemia, ChronicView official trial listing → -
Active, not recruiting NCT NCT02250937
Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Not yet reported M.D. Anderson Cancer Center 116 participants Est. completion 2027-10-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT02265731
Study Evaluating Venetoclax in Subjects With Hematological Malignancies
Not yet reported, Not yet reported AbbVie 38 participants Est. completion 2021-03-12 14 sites Stand-aloneOther conditions: Non-Hodgkin Lymphoma (NHL), Multiple Myeloma (MM), Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL), Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT02287233
A Study Evaluating Venetoclax in Combination With Low-Dose Cytarabine in Treatment-Naïve Participants With Acute Myelogenous Leukemia
Not yet reported, Not yet reported AbbVie 94 participants Est. completion 2021-08-10 9 sites Stand-aloneOther conditions: Acute Myelogenous Leukemia, AMLView official trial listing → -
Completed NCT NCT02296918
Acalabrutinib in Combination With Anti-CD20 and Venetoclax in Relapsed/Refractory or Untreated CLL/SLL/PLL
Not yet reported Acerta Pharma BV 69 participants Est. completion 2025-10-22 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Prolymphocytic LeukemiaView official trial listing → -
Completed NCT NCT02391480
A Study Evaluating the Safety and Pharmacokinetics of ABBV-075 in Subjects With Cancer
Not yet reported AbbVie 128 participants Est. completion 2019-07-05 10 sites Stand-aloneOther conditions: Cancer, Breast Cancer, Non-Small Cell Lung Cancer, Acute Myeloid Leukemia (AML), Multiple Myeloma, Prostate Cancer, Small Cell Lung Cancer, Non-Hodgkins LymphomaView official trial listing → -
Terminated NCT NCT02392572
ONC201 in Treating Patients With Relapsed or Refractory Acute Leukemia or High-Risk Myelodysplastic Syndrome
Not yet reported, Not yet reported M.D. Anderson Cancer Center 58 participants Est. completion 2026-08-14 1 site Stand-aloneOther conditions: Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT02397720
Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 150 participants Est. completion 2023-10-09 1 site Stand-aloneOther conditions: Acute Bilineal Leukemia, Acute Biphenotypic Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Therapy-Related Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02401503
Sequential Regimen of Bendamustine-Debulking Followed by ABT-199 and GA101-Induction and -Maintenance in CLL (CLL2-BAG)
Not yet reported German CLL Study Group 66 participants Est. completion 2024-12-17 1 siteOther conditions: Chronic Lymphocytic LeucemiaView official trial listing → -
Completed NCT NCT02406742
A Phase 1/2, Open-label, Dose Finding Study to Evaluate CC-122 in Combination With Ibrutinib and Obinutuzumab in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Not yet reported, Not yet reported Celgene 47 participants Est. completion 2020-07-07 24 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Completed NCT NCT02419560
Optimal Dose Finding Study ABT-199 and Ibrutinib in MCL
Not yet reported Craig Portell, MD 37 participants Est. completion 2021-05 4 sitesOther conditions: Lymphoma, Mantle-Cell, Recurrent Lymphoma, Mantle-CellView official trial listing → -
Active, not recruiting NCT NCT02427451
Bcl-2 Inhibitor GDC-0199 in Combination With Obinutuzumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or Previously Untreated Chronic Lymphocytic Leukemia
Not yet reported, Not yet reported Kerry Rogers 87 participants Est. completion 2027-04-15 1 siteOther conditions: Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT02471391
ABT-199 & Ibrutinib in Mantle Cell Lymphoma (AIM)
Not yet reported Peter MacCallum Cancer Centre, Australia 37 participants Est. completion 2025-06 2 sitesOther conditions: Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT02558816
A Trial of Obinutuzumab,GDC-0199 Plus Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma Patients
Not yet reported, Not yet reported Nantes University Hospital 48 participants Est. completion 2025-05-13 9 sitesOther conditions: Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT02611323
A Study of Obinutuzumab, Rituximab, Polatuzumab Vedotin, and Venetoclax in Relapsed or Refractory Follicular Lymphoma (FL) or Diffuse Large B-Cell Lymphoma (DLBCL)
Not yet reported, Not yet reported Hoffmann-La Roche 133 participants Est. completion 2022-08-04 23 sites Stand-aloneOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT02639910
Study to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi
Not yet reported MorphoSys AG 24 participants Est. completion 2021-12 17 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-Cell, Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Withdrawn NCT NCT02640833
A Study of Duvelisib and Venetoclax in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Indolent or Aggressive Non-Hodgkin Lymphoma, Who Have Not Previously Received a Bcl-2 or PI3K Inhibitor
Not yet reported AbbVie Est. completion 2021-02 10 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Non-Hodgkin LymphomaView official trial listing → -
Active, not recruiting NCT NCT02665065
Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported Actinium Pharmaceuticals 153 participants Est. completion 2026-12 24 sitesOther conditions: Acute Myeloid Leukemia, Leukemia, Acute Myeloid, Myeloid Leukemia, Acute, Leukemia, Myeloid, Acute, Acute Myelogenous Leukemia, Leukemia, Acute Myelogenous, Myelogenous Leukemia, Acute, AML, Bone Marrow TransplantView official trial listing → -
Completed NCT NCT02670044
A Study of Venetoclax in Combination With Cobimetinib and Venetoclax in Combination With Idasanutlin in Patients With Relapsed or Refractory Acute Myeloid Leukemia Who Are Not Eligible for Cytotoxic Therapy
Not yet reported Hoffmann-La Roche 88 participants Est. completion 2020-12-10 17 sites Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Completed NCT NCT02677324
Study of ABT-199 (GDC-199) In Patients With Relapsed Or Refractory Waldenström Macroglobulinemia
Not yet reported Dana-Farber Cancer Institute 33 participants Est. completion 2022-02-07 4 sitesOther conditions: Waldenstrom MacroglobulinemiaView official trial listing → -
Active, not recruiting NCT NCT02689440
Dasatinib and Venetoclax in Treating Patients With Philadelphia Chromosome Positive or BCR-ABL1 Positive Early Chronic Phase Chronic Myelogenous Leukemia
Not yet reported M.D. Anderson Cancer Center 155 participants Est. completion 2040-12-31 1 site Stand-aloneOther conditions: Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Philadelphia Chromosome Positive, BCR-ABL1 Positive Chronic Myelogenous LeukemiaView official trial listing → -
Active, not recruiting NCT NCT02717624
A Study of Acalabrutinib in Combination With Rituximab + (Bendamustine or Venetoclax) in Subjects With MCL
Not yet reported Acerta Pharma BV 72 participants Est. completion 2027-08-20 15 sites Stand-aloneOther conditions: Mantle Cell Lymphoma (MCL)View official trial listing → -
Completed NCT NCT02755597
A Study Evaluating Venetoclax (ABT-199) in Multiple Myeloma Subjects Who Are Receiving Bortezomib and Dexamethasone as Standard Therapy
Not yet reported AbbVie 291 participants Est. completion 2022-08-15 97 sites Stand-aloneOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Completed NCT NCT02756611
A Study to Evaluate the Efficacy of Venetoclax Monotherapy in Relapsed/Refractory Participants With Chronic Lymphocytic Leukemia (CLL)
Not yet reported AbbVie 258 participants Est. completion 2022-03-11 67 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT02756897
Venetoclax and Ibrutinib in Treating Patients With Chronic or Small Lymphocytic Leukemia
Not yet reported M.D. Anderson Cancer Center 234 participants Est. completion 2027-07-01 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Small Lymphocytic Lymphoma, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT02758665
Trial of Ibrutinib Plus Venetoclax Plus Obinutuzumab in Patients With CLL
Not yet reported University of Ulm 41 participants Est. completion 2022-03 11 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, ChronicView official trial listing → -
Active, not recruiting NCT NCT02846623
Atezolizumab, Obinutuzumab, and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Relapsed or Refractory Richter Syndrome
Not yet reported M.D. Anderson Cancer Center 50 participants Est. completion 2027-02-28 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Recurrent Transformed Chronic Lymphocytic Leukemia, Refractory Transformed Chronic Lymphocytic Leukemia, Richter Syndrome, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT02877550
Obinutuzumab in Combination With Venetoclax in Previously Untreated Follicular Lymphoma Patients
Not yet reported Swiss Cancer Institute 25 participants Est. completion 2022-05-04 6 sites Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Active, not recruiting NCT NCT02899052
Study of Venetoclax in Combination With Carfilzomib and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma (MM)
Not yet reported AbbVie 120 participants Est. completion 2027-06 32 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT02910583
Ibrutinib Plus Venetoclax in Subjects With Treatment-naive Chronic Lymphocytic Leukemia /Small Lymphocytic Lymphoma (CLL/SLL)
Not yet reported Pharmacyclics LLC. 323 participants Est. completion 2024-03-27 46 sites Stand-aloneOther conditions: Leukemia, Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT02942290
A Study Evaluating Venetoclax in Combination With Azacitidine in Participants With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS)
Not yet reported AbbVie 134 participants Est. completion 2026-04-15 37 sites Stand-aloneOther conditions: Myelodysplastic Syndromes (MDS)View official trial listing → -
Completed NCT NCT02950051
Standard Chemoimmunotherapy (FCR/BR) Versus Rituximab + Venetoclax (RVe) Versus Obinutuzumab (GA101) + Venetoclax (GVe) Versus Obinutuzumab + Ibrutinib + Venetoclax (GIVe) in Fit Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without Del(17p) or TP53 Mutation
Not yet reported German CLL Study Group 926 participants Est. completion 2024-02-29 161 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Withdrawn NCT NCT02951117
A Study of Venetoclax and ABBV-838 Combination Therapy With Dexamethasone in Participants With Multiple Myeloma Whose Cancer Has Come Back or Had No Response to Recent Cancer Treatment
Not yet reported AbbVie Est. completion 2021-04-28 3 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT02956382
Ibrutinib and Venetoclax in Relapsed and Refractory Follicular Lymphoma
Not yet reported, Not yet reported Georgetown University 24 participants Est. completion 2024-03-07 3 sites Stand-aloneOther conditions: Refractory Follicular Lymphoma, Relapsed Follicular LymphomaView official trial listing → -
Active, not recruiting NCT NCT02966756
A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Not yet reported AbbVie 66 participants Est. completion 2030-12 31 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)View official trial listing → -
Completed NCT NCT02966782
A Study Evaluating Venetoclax Alone and in Combination With Azacitidine in Participants With Relapsed/Refractory Myelodysplastic Syndromes (MDS)
Not yet reported AbbVie 70 participants Est. completion 2023-04-05 23 sites Stand-aloneOther conditions: Myelodysplastic Syndromes (MDS)View official trial listing → -
Completed NCT NCT02980731
A Study Evaluating the Impact of Venetoclax on the Quality of Life for Subjects With Relapsed (Your Cancer Has Come Back) or Refractory (no Response to Previous Cancer Treatments) Chronic Lymphocytic Leukemia (CLL) While Receiving Venetoclax Monotherapy (a Single Agent).
Not yet reported AbbVie 210 participants Est. completion 2021-12-29 33 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Completed NCT NCT02987400
Combination of Obinutuzumab and Venetoclax in Relapsed or Refractory DLBCL
Not yet reported Arbeitsgemeinschaft medikamentoese Tumortherapie 22 participants Est. completion 2021-10-19 6 sites Stand-aloneOther conditions: Lymphoma, Large B-Cell, DiffuseView official trial listing → -
Active, not recruiting NCT NCT02992522
Obinutuzumab, Venetoclax, and Lenalidomide in Treating Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported Beth Christian 22 participants Est. completion 2027-04-15 2 sites Stand-aloneOther conditions: B-Cell Lymphoma, Unspecified, Grade 1 Follicular Lymphoma, Grade 2 Follicular Lymphoma, Grade 3a Follicular Lymphoma, Recurrent Burkitt Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Follicular Lymphoma, Recurrent Marginal Zone Lymphoma, Refractory Burkitt Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Follicular Lymphoma, Transformed Recurrent Non-Hodgkin Lymphoma, B-CellView official trial listing → -
Active, not recruiting NCT NCT02993523
A Study of Venetoclax in Combination With Azacitidine Versus Azacitidine in Treatment Naïve Participants With Acute Myeloid Leukemia Who Are Ineligible for Standard Induction Therapy
Not yet reported AbbVie 443 participants Est. completion 2026-06-15 172 sitesOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT03000257
A Study of Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors
Not yet reported AbbVie 182 participants Est. completion 2022-03-29 26 sites Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Terminated NCT NCT03000660
Trial of Venetoclax (ABT-199) and Dexamethasone for Relapsed or Refractory Systemic AL Amyloidosis
Not yet reported Tufts Medical Center 3 participants Est. completion 2019-10-10 1 site Stand-aloneOther conditions: AL AmyloidosisView official trial listing → -
Completed NCT NCT03036904
Study of Venetoclax Plus DA-EPOCH-R for the Treatment of Aggressive B-Cell Lymphomas
Not yet reported Weill Medical College of Cornell University 31 participants Est. completion 2021-11-11 6 sites Stand-aloneOther conditions: Diffuse Large B-Cell Lymphoma, High Grade B-Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT03041688
Testing a New Chemotherapy Drug, KRT-232 (AMG-232) in Combination With Decitabine and Venetoclax in Patients With Acute Myeloid Leukemia
Not yet reported National Cancer Institute (NCI) 58 participants Est. completion 2027-06-30 13 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Secondary Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03045328
Venetoclax and Ibrutinib in Patients With Relapsed/Refractory CLL or SLL
Not yet reported Steven E. Coutre 22 participants Est. completion 2021-08-05 2 sites Stand-aloneOther conditions: Recurrent Chronic Lymphocytic Leukemia, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Small Lymphocytic LymphomaView official trial listing → -
Active, not recruiting NCT NCT03054896
A Phase II Study of Venetoclax in Combination With Dose-adjusted EPOCH-R or R-CHOP for Patients With Richter's Syndrome
Not yet reported Dana-Farber Cancer Institute 69 participants Est. completion 2027-12-01 3 sites Stand-aloneOther conditions: Richter SyndromeView official trial listing → -
Completed NCT NCT03063944
STAT Inhibitor OPB-111077, Decitabine and Venetoclax in Treating Patients With Acute Myeloid Leukemia That Is Refractory, Relapsed or Newly Diagnosed and Ineligible for Intensive Chemotherapy
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 37 participants Est. completion 2024-03-04 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03064867
Venetoclax Plus R-ICE Chemotherapy for Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Not yet reported, Not yet reported Molly Gallogly 65 participants Est. completion 2023-08-12 3 sites Stand-aloneOther conditions: Diffuse Large B-cell-lymphomaView official trial listing → -
Completed NCT NCT03069352
A Study of Venetoclax in Combination With Low Dose Cytarabine Versus Low Dose Cytarabine Alone in Treatment Naive Patients With Acute Myeloid Leukemia Who Are Ineligible for Intensive Chemotherapy
Not yet reported AbbVie 211 participants Est. completion 2025-08-21 109 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT03082209
A Study of the Safety and Tolerability of ABBV-621 in Participants With Previously-Treated Solid Tumors and Hematologic Malignancies
Not yet reported AbbVie 153 participants Est. completion 2022-01-21 19 sites Stand-aloneOther conditions: Advanced Solid Tumors, Cancer, Hematologic MalignanciesView official trial listing → -
Completed NCT NCT03112174
Study of Ibrutinib Combined With Venetoclax in Subjects With Mantle Cell Lymphoma (MCL)
Not yet reported Pharmacyclics LLC. 366 participants Est. completion 2024-06-27 120 sites Stand-aloneOther conditions: Mantle-Cell LymphomaView official trial listing → -
Completed NCT NCT03113422
Phase II Venetoclax, Obinutuzumab and Bendamustine in High Tumor Burden Follicular Lymphoma as Front Line Therapy
Not yet reported PrECOG, LLC. 56 participants Est. completion 2023-01-06 10 sites Stand-aloneOther conditions: Follicular Lymphoma, Non-Hodgkin's Lymphoma Follicular, Non-Hodgkin's Lymphoma, Adult High GradeView official trial listing → -
Available NCT NCT03123029
Expanded Access to Venetoclax
AbbVieOther conditions: Chronic Lymphocytic Leukemia (CLL), Multiple Myeloma, Acute Myeloid Leukemia (AML), Non-Hodgkin's Lymphoma, Acute Lymphoblastic Leukemia (ALL), Amyloidosis, Plasma Cell LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03128879
Venetoclax With Ibrutinib or Acalabrutinib in Pts. With High-risk CLL
Not yet reported M.D. Anderson Cancer Center 59 participants Est. completion 2027-05-31 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT03135262
A Study of Obinutuzumab in Combination With Idasanutlin and Venetoclax in Participants With Relapsed or Refractory (R/R) Follicular Lymphoma (FL) or Rituximab in Combination With Idasanutlin and Venetoclax in Participants With R/R Diffuse Large B-Cell Lymphoma (DLBCL)
Not yet reported, Not yet reported Hoffmann-La Roche 29 participants Est. completion 2020-04-30 21 sites Stand-aloneOther conditions: Follicular Lymphoma, Lymphoma, Large B-Cell, DiffuseView official trial listing → -
Terminated NCT NCT03136497
A Study of ABT-199 Plus Ibrutinib and Rituximab in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma
Not yet reported Hackensack Meridian Health 10 participants Est. completion 2020-11-09 1 siteOther conditions: Relapsed Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell LymphomaView official trial listing → -
Terminated NCT NCT03176277
A Study of ONO-7475 in Patients With Acute Leukemias
Not yet reported, Not yet reported Ono Pharmaceutical Co., Ltd. 42 participants Est. completion 2023-01-20 16 sites Stand-aloneOther conditions: Acute Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT03181126
A Study of Venetoclax in Combination With Navitoclax and Chemotherapy in Subjects With Relapsed/Refractory Acute Lymphoblastic Leukemia or Relapsed/Refractory Lymphoblastic Lymphoma
Not yet reported AbbVie 69 participants Est. completion 2020-11-14 15 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL), Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT03194932
Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage
Not yet reported St. Jude Children's Research Hospital 62 participants Est. completion 2022-06-22 3 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT03217838
Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD2811 Nanoparticles as Monotherapy or in Combination in Acute Myeloid Leukemia Participants.
Not yet reported AstraZeneca 50 participants Est. completion 2021-03-25 11 sites Stand-aloneOther conditions: Acute Myeloid LeukaemiaView official trial listing → -
Terminated NCT NCT03218683
Study of AZD5991 Alone or in Combination With Venetoclax in Relapsed or Refractory Haematologic Malignancies.
Not yet reported AstraZeneca 70 participants Est. completion 2021-10-08 10 sites Stand-aloneOther conditions: Relapsed or Refractory Acute Myeloid Leukemia (AML)View official trial listing → -
Status unknown NCT NCT03226301
A Prospective, Multicenter, Phase-II Trial of Ibrutinib Plus Venetoclax in Patients With Creatinine Clearance >= 30 ml/Min Who Have Relapsed or Refractory Chronic Lymphocytic Leukemia (RR-CLL) With or Without TP53 Aberrations
Not yet reported Stichting Hemato-Oncologie voor Volwassenen Nederland 230 participants Est. completion 2026-06-21 49 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia in Relapse, Chronic Lymphocytic Leukemia in RemissionView official trial listing → -
Completed NCT NCT03226418
Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia
Not yet reported University of Nebraska 75 participants Est. completion 2024-10-01 1 site Stand-aloneOther conditions: Adult Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Therapy-Related Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03236857
A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies
Not yet reported AbbVie 143 participants Est. completion 2023-04-19 31 sites Stand-aloneOther conditions: Malignancies, Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Non-Hodgkin's Lymphoma, NeuroblastomaView official trial listing → -
Completed NCT NCT03255096
A Study to Evaluate Safety, Pharmacokinetics, and Clinical Activity of Combination of RO6870810 and Venetoclax, With or Without Rituximab, in Participants With Relapsed/Refractory DLBCL and/or High-Grade B-Cell Lymphoma and/or High Grade B-Cell Lymphoma With MYC and/or BCL2 and/or BCL6
Not yet reported Hoffmann-La Roche 39 participants Est. completion 2019-07-03 9 sites Stand-aloneOther conditions: Diffuse Large B-cell Lymphoma, High-Grade B-cell LymphomaView official trial listing → -
Completed NCT NCT03276468
Evaluation of Atezolizumab-Venetoclax-Obinutuzumab Combination in Relapse/Refractory Lymphomas
Not yet reported The Lymphoma Academic Research Organisation 136 participants Est. completion 2022-08-24 25 sites Stand-aloneObstructive sleep apnea Other conditions: Follicular Lymphoma, Diffuse Large B Cell Lymphoma, Marginal Zone LymphomaView official trial listing → -
Completed NCT NCT03295240
The Study of Bendamustine, Rituximab, Ibrutinib, and Venetoclax in Relapsed, Refractory Mantle Cell Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 10 participants Est. completion 2024-01-22 7 sites Stand-aloneOther conditions: Mantle Cell Lymphoma, LymphomaView official trial listing → -
Completed NCT NCT03310190
Study to Describe the Management and the Use of Healthcare Resources in Patients With Chronic Lymphocytic Leukemia (CLL) Initiating Venetoclax in Routine Clinical Practice
AbbVie 93 participants Est. completion 2022-04-30 13 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT03312530
A Study of Cobimetinib Administered as Single Agent and in Combination With Venetoclax, With or Without Atezolizumab, in Participants With Relapsed and Refractory Multiple Myeloma
Not yet reported, Not yet reported Hoffmann-La Roche 49 participants Est. completion 2021-05-18 26 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT03314181
A Study of Combination Therapy With Venetoclax, Daratumumab and Dexamethasone (With and Without Bortezomib) in Participants With Relapsed or Refractory Multiple Myeloma
Not yet reported AbbVie 156 participants Est. completion 2031-05 40 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT03319901
Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL
Not yet reported, Not yet reported Dana-Farber Cancer Institute 82 participants Est. completion 2028-05-30 5 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03331198
Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)
Not yet reported, Not yet reported Juno Therapeutics, a Subsidiary of Celgene 320 participants Est. completion 2027-11-26 84 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Small LymphocyticView official trial listing → -
Active, not recruiting NCT NCT03336333
A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL
Not yet reported BeiGene 590 participants Est. completion 2027-10-31 158 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Withdrawn NCT NCT03343678
This Study in Patients With Chronic Lymphocytic Leukaemia is Done to Determine a Safe and Effective Dose of BI 836826 in Combination With Venetoclax
Not yet reported Boehringer Ingelheim Est. completion 2020-11-25 Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Completed NCT NCT03357627
A Study of TAK-659 in Combination With Venetoclax for Adult Participants With Previously Treated Non-Hodgkin Lymphoma
Not yet reported Calithera Biosciences, Inc 43 participants Est. completion 2021-08-03 15 sites Stand-aloneOther conditions: Lymphoma, Non-Hodgkin, Lymphoma, Large B-cell, Diffuse, Lymphoma, FollicularView official trial listing → -
Terminated NCT NCT03379051
Phase I/II Study of Venetoclax or Lenalidomide in Combination With Ublituximab and Umbralisib in Subjects With Relapsed or Refractory CLL/SLL and NHL
Not yet reported, Not yet reported TG Therapeutics, Inc. 78 participants Est. completion 2022-06-16 3 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT03390296
OX40, Venetoclax, Avelumab, Glasdegib, Gemtuzumab Ozogamicin, and Azacitidine in Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 50 participants Est. completion 2022-02-04 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03399539
Venetoclax, Ixazomib Citrate, and Dexamethasone in Treating Patients with Relapsed Multiple Myeloma
Not yet reported Mayo Clinic 8 participants Est. completion 2024-02-23 3 sites Stand-aloneOther conditions: Recurrent Plasma Cell Myeloma, T(11;14)View official trial listing → -
Terminated NCT NCT03404193
Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome
Not yet reported M.D. Anderson Cancer Center 235 participants Est. completion 2026-03-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Blastic Plasmacytoid Dendritic Cell Neoplasm, Chronic Myelomonocytic Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome, Recurrent Acute Biphenotypic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm, Recurrent Chronic Myelomonocytic Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Refractory Acute Myeloid Leukemia, Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm, Refractory Chronic Myelomonocytic Leukemia, Refractory Mixed Phenotype Acute LeukemiaView official trial listing → -
Completed NCT NCT03406156
A Study in Previously Untreated Chronic Lymphocytic Leukemia (CLL) Subjects, Excluding Those With the 17p Deletion, to Evaluate Debulking Regimens Prior to Initiating Venetoclax Combination Therapy
Not yet reported AbbVie 120 participants Est. completion 2023-07-12 15 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)View official trial listing → -
Completed NCT NCT03415035
Study Venetoclax Effectiveness and Real-Life Treatment Management in Participants With Chronic Lymphocytic Leukemia
AbbVie 269 participants Est. completion 2026-06-17 60 sitesOther conditions: Cancer - Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03422393
Venetoclax With High-dose Ibrutinib for CLL Progressing on Single Agent Ibrutinib
Not yet reported Michael Choi 24 participants Est. completion 2028-08 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT03441555
A Study of Venetoclax and Alvocidib in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported AbbVie 36 participants Est. completion 2021-01-25 14 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT03455504
Venetoclax Add in Combination With Fludarabine, Cyratabine and Idarubicine in Induction for Acute Myelid Leukemia
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 124 participants Est. completion 2026-07-15 22 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03455517
Activity and Safety of Front-line Venetoclax and Rituximab in Young and Fit Patients With Chronic Lymphocytic Leukemia
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 77 participants Est. completion 2023-05-11 31 sites Stand-aloneOther conditions: Chronic Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03462719
A Study of the Combination of Ibrutinib Plus Venetoclax Versus Chlorambucil Plus Obinutuzumab for the First-line Treatment of Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Not yet reported Janssen Research & Development, LLC 211 participants Est. completion 2029-04-05 88 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Completed NCT NCT03466294
Azacitidine and Venetoclax as Induction Therapy With Venetoclax Maintenance in the Elderly With AML
Not yet reported University of Colorado, Denver 42 participants Est. completion 2025-12-04 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03467867
A Study of Venetoclax and Rituximab/Hyaluronidase Human in Relapsed/Refractory CLL
Not yet reported Georgetown University 25 participants Est. completion 2026-12 2 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT03484520
A Study of Venetoclax and Dinaciclib (MK7965) in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported AbbVie 48 participants Est. completion 2022-12-01 13 sites Stand-aloneOther conditions: Cancer - Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03485547
Study of Venetoclax, a BCL2 Antagonist, for Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Not yet reported Dana-Farber Cancer Institute 5 participants Est. completion 2025-04-16 2 sites Stand-aloneOther conditions: Blastic Plasmacytoid Dendritic Cell NeoplasmView official trial listing → -
Terminated NCT NCT03492125
A Study Of The Selective PKC-β Inhibitor MS- 553
Not yet reported, Not yet reported MingSight Pharmaceuticals, Inc 60 participants Est. completion 2023-11-28 5 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Aggressive LymphomaView official trial listing → -
Active, not recruiting NCT NCT03504644
Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported ECOG-ACRIN Cancer Research Group 40 participants Est. completion 2028-12-31 170 sites Stand-aloneOther conditions: Recurrent Adult Lymphoblastic Lymphoma, Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma, Recurrent T Acute Lymphoblastic Leukemia, Recurrent T Lymphoblastic Lymphoma, Refractory B Acute Lymphoblastic Leukemia, Refractory B Lymphoblastic Lymphoma, Refractory T Acute Lymphoblastic Leukemia, Refractory T Lymphoblastic LymphomaView official trial listing → -
Status unknown NCT NCT03505944
Venetoclax, Lenalidomide and Rituximab in Patients With Relapsed/Refractory Mantle Cell Lymphoma
Not yet reported, Not yet reported Nordic Lymphoma Group 59 participants Est. completion 2022-12-01 17 sites Stand-aloneOther conditions: Relapsed Non Hodgkin LymphomaView official trial listing → -
Active, not recruiting NCT NCT03513562
Venetoclax and Ibrutinib in Treating in Participants With Chronic Lymphocytic Leukemia and Ibrutinib Resistance Mutations
Not yet reported Ohio State University Comprehensive Cancer Center 28 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Ibrutinib ResistanceView official trial listing → -
Terminated NCT NCT03530683
A Clinical Trial to Learn About the Study Medicine Called Maplirpacept (PF-07901801), Alone and When Used in Combination With Other Medicines to Treat Participants With Advanced Hematological Malignancies, Including Lymphoma, Leukemia and Multiple Myeloma
Not yet reported Pfizer 189 participants Est. completion 2024-07-18 62 sites Stand-aloneOther conditions: Lymphoma, Multiple Myeloma, Acute Myeloid Leukemia, Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT03534180
Venetoclax and Romidepsin in Treating Patients With Recurrent or Refractory Mature T-Cell Lymphoma
Not yet reported City of Hope Medical Center 12 participants Est. completion 2023-07-26 2 sites Stand-aloneOther conditions: Anaplastic Large Cell Lymphoma, Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Refractory Mature T-Cell and NK-Cell Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT03534323
Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS
Not yet reported, Not yet reported Dana-Farber Cancer Institute 55 participants Est. completion 2026-07-01 7 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Richter SyndromeView official trial listing → -
Active, not recruiting NCT NCT03539744
A Study Designed to Evaluate the Safety and Efficacy of Venetoclax Plus Dexamethasone (VenDex) Compared With Pomalidomide Plus Dexamethasone (PomDex) in Participants With t(11;14)-Positive Relapsed or Refractory Multiple Myeloma.
Not yet reported AbbVie 265 participants Est. completion 2027-11 180 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Terminated NCT NCT03547115
A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML
Not yet reported MEI Pharma, Inc. 84 participants Est. completion 2024-07-24 12 sites Stand-aloneOther conditions: Follicular Lymphoma (FL), Mantle Cell Lymphoma (MCL), Marginal Zone Lymphoma (MZL), Small Lymphocytic Lymphoma (SLL), Chronic Lymphocytic Leukemia (CLL), Diffuse Large B-cell Lymphoma (DLBCL), Acute Myeloid Leukemia (AML)View official trial listing → -
Terminated NCT NCT03552692
Use of Venetoclax as Single Agent in Patients With Relapsed/Refractory BCL-2 Positive Peripheral T Cell Lymphoma
Not yet reported Fondazione Italiana Linfomi - ETS 22 participants Est. completion 2023-02-17 13 sites Stand-aloneOther conditions: T-Cell Lymphoma Relapsed, T-Cell Lymphoma RefractoryView official trial listing → -
Status unknown NCT NCT03557619
A Study to Assess the Effect of Venetoclax on Ethinyl Estradiol and Levonorgestrel in Female Participants With Different Hematological Malignancies
Not yet reported AbbVie 12 participants Est. completion 2026-03-21 4 sites Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Terminated NCT NCT03567616
A Study of Venetoclax in Combination With Pomalidomide and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma
Not yet reported AbbVie 8 participants Est. completion 2020-06-18 11 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT03567876
Rituximab, Bendamustine and Cytarabine Followed by Venetoclax in High Risk Elderly Patients With MCL
Not yet reported Fondazione Italiana Linfomi - ETS 141 participants Est. completion 2025-10-15 35 sites Stand-aloneOther conditions: Lymphoma, Mantle-CellView official trial listing → -
Completed NCT NCT03573024
Venetoclax and Azacitidine for Non-Elderly Adult Patients With Acute Myeloid Leukemia
Not yet reported University of Colorado, Denver 36 participants Est. completion 2026-02-19 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT03576547
Venetoclax, Ponatinib, and Dexamethasone in Participants With Philadelphia Chromosome or BCR-ABL Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 9 participants Est. completion 2024-06-19 1 site Stand-aloneOther conditions: Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Philadelphia Chromosome Positive, Recurrent Acute Lymphoblastic Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Acute Lymphoblastic Leukemia, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, t(9;22)View official trial listing → -
Active, not recruiting NCT NCT03580928
Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL
Not yet reported Dana-Farber Cancer Institute 72 participants Est. completion 2027-12-31 4 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Completed NCT NCT03583424
Venetoclax, Carmustine, Etoposide, Cytarabine, and Melphalan Before Stem Cell Transplant in Treating Participants With Relapsed or Refractory Non-Hodgkin Lymphoma
Not yet reported, Not yet reported Ohio State University Comprehensive Cancer Center 19 participants Est. completion 2021-09-30 1 site Stand-aloneOther conditions: Hematopoietic Cell Transplantation Recipient, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Non-Hodgkin Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Follicular Lymphoma, Refractory Marginal Zone Lymphoma, Refractory Non-Hodgkin Lymphoma, Refractory Transformed Indolent Non-Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT03584009
A Phase II Study Comparing The Efficacy Of Venetoclax + Fulvestrant Vs. Fulvestrant In Women With Estrogen Receptor-Positive, Her2-Negative Locally Advanced Or Metastatic Breast Cancer Who Experienced Disease Recurrence Or Progression During Or After CDK4/6 Inhibitor Therapy
Not yet reported Hoffmann-La Roche 103 participants Est. completion 2021-05-06 40 sites Stand-aloneOther conditions: Estrogen Receptor-positive (ER+)/Human Epidermal Growth Factor Receptor (HER2)-Negative Locally Advanced or Metastatic Breast CancerView official trial listing → -
No Longer Available NCT NCT03592576
Expanded Access to Navitoclax
AbbVieOther conditions: Myelofibrosis, Acute Lymphocytic Leukemia (ALL), Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT03609593
Bendamustine/Rituximab Followed by Venetoclax and Rituximab for Treatment of Chronic Lymphocytic Leukemia
Not yet reported Nicole Lamanna 42 participants Est. completion 2026-01-27 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03613532
Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN
Not yet reported Jacqueline Garcia, MD 102 participants Est. completion 2030-03-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), MDS/Myeloproliferative Neoplasm-unclassifiable (MDS/MPN-unclassifiable), Hematopoietic Stem Cell TransplantView official trial listing → -
Completed NCT NCT03625505
A Study to Assess Safety and Efficacy of Venetoclax in Combination With Gilteritinib in Participants With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported AbbVie 61 participants Est. completion 2021-08-31 11 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Terminated NCT NCT03634228
Milademetan Tosylate and Low-Dose Cytarabine With or Without Venetoclax in Treating Participants With Recurrent or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 16 participants Est. completion 2022-04-03 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT03639324
Rituximab, Idelalisib, and Venetoclax in Relapsed/Refractory CLL/SLL
Not yet reported Virginia Commonwealth University Est. completion 2021-10-18 Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, CLL, Relapsed CLL, Refractory Chronic Lymphocytic Leukemia, Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, SLL, Relapsed Small Lymphocytic Lymphoma, Refractory Small Lymphocytic LymphomaView official trial listing → -
Suspended NCT NCT03659669
A Study to Describe the Effectiveness and Safety of Venetoclax Treatment in Chronic Lymphocytic Leukemia (CLL) Patients in Routine Clinical Practice
AbbVie 272 participants Est. completion 2027-02-28 13 sitesOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Status unknown NCT NCT03662724
Venetoclax Registry
Hannover Medical School 100 participants Est. completion 2025-11-01 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03672695
Phase I Dose Escalation Study of Intravenously Administered S64315 in Combination With Orally Administered Venetoclax in Patients With Acute Myeloid Leukaemia.
Not yet reported Institut de Recherches Internationales Servier 37 participants Est. completion 2023-05-30 7 sites Stand-aloneOther conditions: Acute Myeloid LeukaemiaView official trial listing → -
Active, not recruiting NCT NCT03701282
Assessing the Ability of Combination Treatment With Venetoclax to Permit Time Limited Therapy in Chronic Lymphocytic Leukemia
Not yet reported National Cancer Institute (NCI) 720 participants Est. completion 2028-05-07 865 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Withdrawn NCT NCT03701321
Daratumumab, Bortezomib, and Dexamethasone With or Without Venetoclax in Treating Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported, Not yet reported National Cancer Institute (NCI) Est. completion 2020-05-28 3 sites Stand-aloneOther conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell MyelomaView official trial listing → -
Terminated NCT NCT03708003
Ibrutinib lead-in Followed by Venetoclax Plus Ibrutinib in Patients With RR CLL
Not yet reported Swiss Cancer Institute 30 participants Est. completion 2025-11-30 11 sites Stand-aloneOther conditions: Relapsed/Refractory Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03709758
Venetoclax in Combination With Intensive Induction and Consolidation Chemotherapy in Treatment Naïve AML
Not yet reported Dana-Farber Cancer Institute 50 participants Est. completion 2026-12-01 2 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03710772
Ibrutinib, Rituximab, Venetoclax, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 51 participants Est. completion 2027-03-22 1 site Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT03713580
Venetoclax in Combination With BEAM Conditioning Regimen for ASCT in Non-Hodgkin Lymphoma
Not yet reported Case Comprehensive Cancer Center 25 participants Est. completion 2025-11-07 2 sites Stand-aloneOther conditions: Non-hodgkin LymphomaView official trial listing → -
Completed NCT NCT03732703
Myeloma-Developing Regimens Using Genomics (MyDRUG)
Not yet reported, Not yet reported Multiple Myeloma Research Consortium 103 participants Est. completion 2024-12-31 16 sites Stand-aloneOther conditions: Relapsed Refractory Multiple MyelomaView official trial listing → -
Terminated NCT NCT03735875
Venetoclax and Quizartinib in Treating Patients With FLT3-mutated Recurrent or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 8 participants Est. completion 2023-07-26 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia With FLT3/ITD Mutation, Recurrent Acute Myeloid Leukemia, Refractory Acute LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03737981
Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia
Not yet reported National Cancer Institute (NCI) 465 participants Est. completion 2026-12-29 857 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT03739554
CYC065 CDK Inhibitor and Venetoclax Study in Relapsed/Refractory CLL
Not yet reported Cyclacel Pharmaceuticals, Inc. 5 participants Est. completion 2023-04-27 3 sites Stand-aloneOther conditions: Relapsed or Refractory Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT03740529
A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL
Not yet reported, Not yet reported Loxo Oncology, Inc. 803 participants Est. completion 2025-12-23 56 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia, Mantle Cell Lymphoma, Marginal Zone Lymphoma, B-cell Lymphoma, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT03751436
Enzalutamide With Venetoclax in Treating Patients With Metastatic Castration Resistant Prostate Cancer
Not yet reported Roswell Park Cancer Institute 10 participants Est. completion 2023-08-11 1 site Stand-aloneOther conditions: Castration Levels of Testosterone, Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Metastatic Prostate Carcinoma in the Soft Tissue, Prostate Carcinoma Metastatic in the Bone, PSA Progression, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8View official trial listing → -
Completed NCT NCT03755947
Ibrutinib, Obinutuzumab and Venetoclax for Patients With Chronic Lymphocytic Leukemia
Not yet reported Grupo Cooperativo de Hemopatías Malignas 3 participants Est. completion 2021-02-01 1 site Stand-aloneOther conditions: B-Cell Chronic Lymphocytic Leukemia, B-Cell Chronic Lymphocytic Leukemia in Relapse (Diagnosis)View official trial listing → -
Active, not recruiting NCT NCT03766763
Preemptive Therapy for High Risk Chronic Lymphoid Leukemia Stage A
Not yet reported French Innovative Leukemia Organisation 82 participants Est. completion 2030-04-24 23 sites Stand-aloneOther conditions: Chronic Lymphoid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03768063
A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study
Not yet reported Hoffmann-La Roche 1000 participants Est. completion 2028-07-05 80 sites Stand-aloneOther conditions: CancerView official trial listing → -
Withdrawn NCT NCT03785184
A Study of Venetoclax Plus Lenalidomide and Dexamethasone for the Treatment of Newly Diagnosed t(11;14)-Positive Multiple Myeloma in Subjects Who Are Ineligible for High-Dose Therapy
Not yet reported AbbVie Est. completion 2019-08-22 22 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT03787264
Sequential Regimen of Bendamustin-Debulking Followed by Obinutuzumab, Acalabrutinib and Venetoclax in Patients With Relapsed/Refractory CLL
Not yet reported German CLL Study Group 46 participants Est. completion 2023-09-26 17 sites Stand-aloneOther conditions: Chronic Lymphoid LeukemiaView official trial listing → -
Terminated NCT NCT03797261
A Study of Venetoclax and AMG 176 in Patients With Relapsed/Refractory Hematologic Malignancies
Not yet reported AbbVie 9 participants Est. completion 2019-12-30 17 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Non-Hodgkin's Lymphoma, Diffuse Large B-cell LymphomaView official trial listing → -
Terminated NCT NCT03801525
Study to Assess the Efficacy and Safety of Ublituximab in Combination With Umbralisib and Venetoclax Compared to Ublituximab in Combination With Umbralisib in Subjects With CLL (ULTRA-V)
Not yet reported, Not yet reported TG Therapeutics, Inc. 277 participants Est. completion 2022-12-20 50 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Terminated NCT NCT03808610
Low-Intensity Chemotherapy and Venetoclax in Treating Patients With Relapsed or Refractory B- or T-Cell Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 53 participants Est. completion 2026-05-05 1 site Stand-aloneOther conditions: Recurrent B Acute Lymphoblastic Leukemia, Recurrent T Acute Lymphoblastic Leukemia, Refractory B Acute Lymphoblastic Leukemia, Refractory T Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03824483
Study of Zanubrutinib, Obinutuzumab, and Venetoclax in Patients With Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL)
Not yet reported Memorial Sloan Kettering Cancer Center 230 participants Est. completion 2027-02 8 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Leukemia (SLL)View official trial listing → -
Completed NCT NCT03834688
Phase II Study of Bendamustine and Rituximab Plus Venetoclax in Untreated Mantle Cell Lymphoma Over 60 Years of Age
Not yet reported PrECOG, LLC. 33 participants Est. completion 2024-07-26 7 sites Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT03836261
Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL
Not yet reported Acerta Pharma BV 984 participants Est. completion 2027-04-30 169 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03844048
An Extension Study of Venetoclax for Subjects Who Have Completed a Prior Venetoclax Clinical Trial
Not yet reported AbbVie 165 participants Est. completion 2027-08 56 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Acute Myeloid Leukemia, Multiple Myeloma, Non-Hodgkin's Lymphoma, Acute Lymphoblastic Leukemia, CancerView official trial listing → -
Active, not recruiting NCT NCT03844815
Study of Venetoclax in Combination With Decitabine in Subjects With Acute Myeloid Leukemia
Not yet reported University of Chicago 26 participants Est. completion 2027-12-10 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT03856112
Ixazomib and Dexamethasone With or Without Venetoclax in Treating Patients With Non-t(11;14) Relapsed or Refractory Multiple Myeloma
Not yet reported, Not yet reported National Cancer Institute (NCI) Est. completion 2021-12-31 Stand-aloneOther conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma, t(11;14) NegativeView official trial listing → -
Active, not recruiting NCT NCT03862157
Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2027-01-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Chronic Eosinophilic Leukemia, Not Otherwise Specified, Chronic Myelomonocytic Leukemia, Chronic Neutrophilic Leukemia, Essential Thrombocythemia, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Myeloid Neoplasm, Myeloproliferative Neoplasm, Myeloproliferative Neoplasm, Unclassifiable, Overt Primary Myelofibrosis, Polycythemia Vera, Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase, Prefibrotic/Early Primary MyelofibrosisView official trial listing → -
Status unknown NCT NCT03867682
Venetoclax and Lintuzumab-Ac225 in AML Patients
Not yet reported, Not yet reported Actinium Pharmaceuticals 38 participants Est. completion 2024-06 5 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Relapsed Adult AMLView official trial listing → -
Active, not recruiting NCT NCT03872180
Bendamustine, Obinutuzumab, and Venetoclax in Patients With Untreated Mantle Cell Lymphoma
Not yet reported Emory University 23 participants Est. completion 2027-07-15 3 sites Stand-aloneOther conditions: CCND1 Positive, Mantle Cell Lymphoma, t(11;14) PositiveView official trial listing → -
Completed NCT NCT03873493
A Study Evaluating the Efficacy of Venetoclax Plus Ibrutinib in Participants With T-cell Prolymphocytic Leukemia
Not yet reported AbbVie 14 participants Est. completion 2021-11-04 15 sites Stand-aloneOther conditions: Leukemia, T-cell Prolymphocytic Leukemia (T-PLL), CancerView official trial listing → -
Completed NCT NCT03873857
A Study to Assess Effectiveness of Venclexta (Venetoclax) in Patients With Relapse or Refractory Chronic Lymphocytic Leukemia in Routine Clinical Practice in Russian Federation
AbbVie 71 participants Est. completion 2022-09-12 20 sitesOther conditions: Chronic Lymphocytic Leukemia (CLL), CancerView official trial listing → -
Terminated NCT NCT03878524
Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial
Not yet reported OHSU Knight Cancer Institute 2 participants Est. completion 2020-12-10 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Anatomic Stage IV Breast Cancer AJCC v8, Anemia, Ann Arbor Stage III Hodgkin Lymphoma, Ann Arbor Stage III Non-Hodgkin Lymphoma, Ann Arbor Stage IV Hodgkin Lymphoma, Ann Arbor Stage IV Non-Hodgkin Lymphoma, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Castration-Resistant Prostate Carcinoma, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid System Neoplasm, Locally Advanced Pancreatic Adenocarcinoma, Metastatic Breast Carcinoma, Metastatic Malignant Solid Neoplasm, Metastatic Pancreatic Adenocarcinoma, Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Primary Myelofibrosis, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Hematologic Malignancy, Recurrent Hodgkin Lymphoma, Recurrent Myelodysplastic Syndrome, Recurrent Myelodysplastic/Myeloproliferative Neoplasm, Recurrent Myeloproliferative Neoplasm, Recurrent Non-Hodgkin Lymphoma, Recurrent Plasma Cell Myeloma, Recurrent Small Lymphocytic Lymphoma, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Chronic Lymphocytic Leukemia, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Chronic Myelomonocytic Leukemia, Refractory Hematologic Malignancy, Refractory Hodgkin Lymphoma, Refractory Malignant Solid Neoplasm, Refractory Myelodysplastic Syndrome, Refractory Myelodysplastic/Myeloproliferative Neoplasm, Refractory Non-Hodgkin Lymphoma, Refractory Plasma Cell Myeloma, Refractory Primary Myelofibrosis, Refractory Small Lymphocytic Lymphoma, Stage II Pancreatic Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8, Unresectable Pancreatic AdenocarcinomaView official trial listing → -
Withdrawn NCT NCT03884972
Trabectedin and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Resistant or Intolerant to a BTK Inhibitor
Not yet reported M.D. Anderson Cancer Center Est. completion 2020-03-04 1 site Stand-aloneOther conditions: Refractory Chronic Lymphocytic Leukemia, Refractory Small Lymphocytic LymphomaView official trial listing → -
Terminated NCT NCT03886649
Copanlisib in Combination With Venetoclax in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma.
Not yet reported Swiss Cancer Institute 7 participants Est. completion 2022-03-08 6 sites Stand-aloneOther conditions: Non-Hodgkin LymphomaView official trial listing → -
Active, not recruiting NCT NCT03900884
Palbociclib, Letrozole & Venetoclax in ER and BCL-2 Positive Breast Cancer
Not yet reported Peter MacCallum Cancer Centre, Australia 17 participants Est. completion 2025-12 3 sites Stand-aloneOther conditions: Breast Neoplasm FemaleView official trial listing → -
Terminated NCT NCT03922100
Study of NMS-03592088 in Patients With Relapsed or Refractory AML or CMML
Not yet reported, Not yet reported Nerviano Medical Sciences 63 participants Est. completion 2024-08-29 11 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Chronic Myelomonocytic Leukemia (CMML)View official trial listing → -
Terminated NCT NCT03926624
Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage
Not yet reported Delta-Fly Pharma, Inc. 167 participants Est. completion 2026-01-07 39 sitesOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Withdrawn NCT NCT03932318
Venetoclax, Azacitidine, and Lintuzumab-Ac225 in AML Patients
Not yet reported, Not yet reported Actinium Pharmaceuticals Est. completion 2024-09 Stand-aloneOther conditions: Acute Myeloid Leukemia, Relapsed Adult AMLView official trial listing → -
Terminated NCT NCT03940352
HDM201 in Combination With MBG453 or Venetoclax in Patients With Acute Myeloid Leukemia (AML) or High-risk Myelodysplastic Syndrome (MDS)
Not yet reported Novartis Pharmaceuticals 52 participants Est. completion 2024-08-20 9 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), High-risk Myelodysplastic Syndrome (MDS)View official trial listing → -
Completed NCT NCT03941964
A Study of the Effectiveness of Venetoclax in Combination With Azacitidine or Decitabine in an Outpatient Setting in Patients With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy
Not yet reported AbbVie 60 participants Est. completion 2022-03-14 16 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), CancerView official trial listing → -
Withdrawn NCT NCT03943342
Ibrutinib and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia After Ibrutinib Resistance
Not yet reported Kerry Rogers Est. completion 2021-07-20 Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Loss of Chromosome 17pView official trial listing → -
Active, not recruiting NCT NCT03946878
Venetoclax and Acalabrutinib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 32 participants Est. completion 2028-02-08 1 site Stand-aloneOther conditions: Blastoid Variant Mantle Cell Lymphoma, CCND1 Protein Overexpression, CD20 Positive, CD5 Positive, FCER2 Negative, Pleomorphic Variant Mantle Cell Lymphoma, Recurrent Mantle Cell Lymphoma, Refractory Mantle Cell Lymphoma, t(11;14)(q13;q32)View official trial listing → -
Completed NCT NCT03955783
Venetoclax and Selinexor in Treating Patients With Relapsed or Refractory High Risk Hematologic Malignancies
Not yet reported Sanjay Mohan 78 participants Est. completion 2024-09-01 4 sites Stand-aloneOther conditions: Diffuse Large B-cell Lymphoma, Acute Myeloid Leukemia, Non-Hodgkin's LymphomaView official trial listing → -
Terminated NCT NCT03969420
Study of Alvocidib in Patients With Relapsed/Refractory AML Following Treatment With Venetoclax Combination Therapy
Not yet reported Sumitomo Pharma America, Inc. 11 participants Est. completion 2021-05-14 18 sitesOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Suspended NCT NCT03969446
Pembrolizumab and Decitabine With or Without Venetoclax in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome That Is Newly-Diagnosed, Recurrent, or Refractory
Not yet reported City of Hope Medical Center 54 participants Est. completion 2027-07-04 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT03980171
Study of Lenalidomide, Venetoclax and Obinutuzumab in Patients With Treatment-Naïve Follicular Lymphoma
Not yet reported, Not yet reported Peter MacCallum Cancer Centre, Australia 50 participants Est. completion 2026-11 3 sites Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Active, not recruiting NCT NCT03984448
Testing the Addition of a New Anti-cancer Drug, Venetoclax, to Usual Chemotherapy for High Grade B-cell Lymphomas
Not yet reported, Not yet reported National Cancer Institute (NCI) 363 participants Est. completion 2028-08-13 634 sites Stand-aloneOther conditions: Diffuse Large B-Cell Lymphoma, Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Double-Expressor Lymphoma, EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, High Grade B-Cell Lymphoma, Not Otherwise Specified, Neoplastic Cells With Double Expression of MYC and BCL2 Proteins Present, Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT03987958
A Study to Describe the Safety and Effectiveness of Venetoclax in Acute Myeloid Leukemia (AML) Patients (REVIVE Study)
AbbVie 100 participants Est. completion 2027-07 12 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT04000698
Personalized Targeted Preparative Regimen Before T-depleted Allogeneic HSCT in Children With Chemoresistent Acute Leukemias
Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 25 participants Est. completion 2022-12 1 site Stand-aloneOther conditions: Refractory Acute Myeloid Leukemia, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT04010968
Evaluation of Risk-Adapted and MRD-Driven Strategy for Untreated Fit Patients With Intermediate Risk Chronic Lymphocytic Leukemia
Not yet reported French Innovative Leukemia Organisation 120 participants Est. completion 2025-01-30 34 sites Stand-aloneOther conditions: Intermediate Risk Chronic Lymphocytic Leukemia, Fit Patients, Risk-Adapted and MRD-Driven StrategyView official trial listing → -
Terminated NCT NCT04016805
Study to Assess the Efficacy and Safety of Ublituximab and Umbralisib in Participants With Chronic Lymphocytic Leukemia (CLL) Currently Treated With Ibrutinib, Acalabrutinib or Venetoclax
Not yet reported TG Therapeutics, Inc. 41 participants Est. completion 2022-05-22 3 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT04017546
CYC065 CDK Inhibitor and Venetoclax Study in Relapsed/Refractory AML or MDS
Not yet reported Cyclacel Pharmaceuticals, Inc. 14 participants Est. completion 2023-04-05 1 site Stand-aloneOther conditions: AML, MDSView official trial listing → -
Terminated NCT NCT04029688
A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors
Not yet reported, Not yet reported Hoffmann-La Roche 38 participants Est. completion 2024-05-06 14 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Neuroblastoma, Solid TumorsView official trial listing → -
Completed NCT NCT04038437
A Trial of CPX-351 Lower Intensity Therapy (LIT) Plus Venetoclax as First Line Treatment for Subjects With AML
Not yet reported Jazz Pharmaceuticals 35 participants Est. completion 2022-09-24 8 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04062266
AZA + Venetoclax as Maintenance Therapy in Patients With AML in Remission
Not yet reported M.D. Anderson Cancer Center 36 participants Est. completion 2026-10-12 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia in Remission, FLT3 Gene Mutation, Hematologic and Lymphocytic Disorder, Acute Myeloid Leukemia, Minimal Residual Disease Persistence, Therapy-Related Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT04070768
Study of the Safety and Efficacy of Gemtuzumab Ozogamicin (GO) and Venetoclax in Patients With Relapsed or Refractory CD33+ Acute Myeloid Leukemia:Big Ten Cancer Research Consortium BTCRC-AML17-113
Not yet reported John Quigley 18 participants Est. completion 2024-02-20 4 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04073147
Venetoclax and Obinutuzumab for Relapsed/Refractory Primary CNS Lymphoma
Not yet reported Klinikum Stuttgart 4 participants Est. completion 2021-11-25 1 site Stand-aloneOther conditions: Primary CNS LymphomaView official trial listing → -
Completed NCT NCT04075747
A Phase 1b Master Trial to Investigate CPX-351 in Subjects With Previously Untreated Acute Myeloid Leukemia
Not yet reported Jazz Pharmaceuticals 57 participants Est. completion 2023-09-12 10 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04082897
ObinutuzuMab AtezOlizumab and VenetocLax in RichTer transfOrmation
Not yet reported Niguarda Hospital 28 participants Est. completion 2026-12 17 sites Stand-aloneOther conditions: CLL TransformationView official trial listing → -
Active, not recruiting NCT NCT04086264
IMGN632 as Monotherapy or With Venetoclax and/or Azacitidine for Participants With CD123-Positive Acute Myeloid Leukemia
Not yet reported, Not yet reported AbbVie 218 participants Est. completion 2027-02 29 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04092179
Study of Enasidenib and Venetoclax in IDH2-Mutated Blood Cancers
Not yet reported, Not yet reported University Health Network, Toronto 27 participants Est. completion 2023-10-26 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Relapsed Cancer, Refractory Cancer, IDH2 Gene MutationView official trial listing → -
Completed NCT NCT04102020
A Study of Oral Venetoclax Tablets and Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy
Not yet reported AbbVie 112 participants Est. completion 2026-02-20 156 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Active, not recruiting NCT NCT04128501
Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting
Not yet reported M.D. Anderson Cancer Center 100 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Acute Bilineal Leukemia, Acute Biphenotypic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, T Acute Lymphoblastic Leukemia, Therapy-Related Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT04146038
Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease
Not yet reported Rutgers, The State University of New Jersey 5 participants Est. completion 2022-10-25 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myeloblasts 10 Percent or More of Bone Marrow Nucleated Cells, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Secondary Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04150029
A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapy
Not yet reported Novartis Pharmaceuticals 90 participants Est. completion 2024-10-25 28 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04150887
Cusatuzumab in Combination With Background Therapy for the Treatment of Participants With Acute Myeloid Leukemia
Not yet reported OncoVerity, Inc. 61 participants Est. completion 2027-05-15 23 sites Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Active, not recruiting NCT NCT04159779
A Study of Clinical Outcomes in Chronic Lymphocytic Leukemia (CLL) Patients Treated With Venetoclax in Greece
AbbVie 180 participants Est. completion 2026-06-30 21 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT04160052
Venetoclax and Azacitidine for the Treatment of High-Risk Recurrent or Refractory Myelodysplastic Syndrome
Not yet reported, Not yet reported M.D. Anderson Cancer Center 51 participants Est. completion 2026-02-03 1 site Stand-aloneOther conditions: Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Recurrent Myelodysplastic Syndrome, Refractory Myelodysplastic Syndrome, Therapy-Related Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT04161248
Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma
Not yet reported Canadian Cancer Trials Group 40 participants Est. completion 2026-12-31 4 sites Stand-aloneOther conditions: Lymphoma, B-CellView official trial listing → -
Terminated NCT NCT04161885
A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML)
Not yet reported AbbVie 465 participants Est. completion 2025-09-23 165 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), CancerView official trial listing → -
Completed NCT NCT04171791
A Study of ABT-199 (Venetoclax) for Cutaneous T Cell Lymphoma (CTCL)
Not yet reported Yale University 4 participants Est. completion 2021-06-22 1 site Stand-aloneOther conditions: CTCLView official trial listing → -
Terminated NCT NCT04172844
Pevonedistat, Azacitidine (or Decitabine), and Venetoclax for the Treatment of Patients With Acute Myelogenous Leukemia
Not yet reported Medical College of Wisconsin 16 participants Est. completion 2022-02-27 2 sites Stand-aloneOther conditions: Acute Myelogenous LeukemiaView official trial listing → -
Completed NCT NCT04178317
A Study of the Safety and Efficacy of Venetoclax for Participants With Chronic Lymphocytic Leukemia (CLL) Used in Routine Clinical Practice
AbbVie 14 participants Est. completion 2025-08-18 13 sitesOther conditions: Cancer, Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Completed NCT NCT04188405
Decitabine, Venetoclax, and Ponatinib for the Treatment of Philadelphia Chromosome-Positive Acute Myeloid Leukemia or Myeloid Blast Phase or Accelerated Phase Chronic Myelogenous Leukemia
Not yet reported M.D. Anderson Cancer Center 20 participants Est. completion 2026-06-02 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Myeloid Leukemia, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Acute Myeloid Leukemia, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 PositiveView official trial listing → -
Completed NCT NCT04198415
A Study of the Safety and Efficacy of Venetoclax in Japanese Participants With Relapsed and Refractory Chronic Lymphocytic Leukemia (Including Small Lymphocytic Leukemia)
AbbVie 4 participants Est. completion 2022-10-21 102 sitesOther conditions: Cancer, Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Leukemia (SLL)View official trial listing → -
Completed NCT NCT04214860
APR-246 in Combination With Venetoclax and Azacitidine in TP53-Mutant Myeloid Malignancies
Not yet reported Aprea Therapeutics 51 participants Est. completion 2022-01-14 8 sites Stand-aloneOther conditions: Myeloid MalignancyView official trial listing → -
Active, not recruiting NCT NCT04227847
A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies
Not yet reported Seagen, a wholly owned subsidiary of Pfizer 170 participants Est. completion 2028-07-03 52 sites Stand-aloneOther conditions: Myelodysplastic Syndrome, Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04229979
Galinpepimut-S Versus Investigator's Choice of Best Available Therapy for Maintenance in AML CR2/CRp2
Not yet reported Sellas Life Sciences Group 127 participants Est. completion 2026-12 73 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT04230564
Acute Myeloid Leukemia Real World Treatment Patterns
Pfizer Est. completion 2021-03-31Other conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Completed NCT NCT04253314
A Study of the Effectiveness of Venetoclax Tablets in Adult Acute Myeloid Leukemia Participants Ineligible for Standard Induction Therapy in Russian Federation
AbbVie 51 participants Est. completion 2023-02-16 10 sitesOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Active, not recruiting NCT NCT04263181
AML/MDS Drug Sensitization by in Vivo Chemotherapy Administration
Washington University School of Medicine 80 participants Est. completion 2027-01-31 1 siteOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT04266795
A Study of Pevonedistat and Venetoclax Combined With Azacitidine to Treat Acute Myeloid Leukemia (AML) in Adults Unable to Receive Intensive Chemotherapy
Not yet reported Takeda 164 participants Est. completion 2025-10-06 57 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT04267081
Study of Venetoclax in Combination With Azacytidine in AML Patients Selected Using Ex Vivo Drug Sensitivity Screening
Not yet reported Helsinki University Central Hospital 104 participants Est. completion 2024-02-28 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04273139
Ibrutinib + Venetoclax in Untreated WM
Not yet reported Dana-Farber Cancer Institute 45 participants Est. completion 2028-02-01 2 sites Stand-aloneOther conditions: Waldenstrom Macroglobulinemia, MYD88 Gene MutationView official trial listing → -
Terminated NCT NCT04274907
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression
Not yet reported AbbVie 2 participants Est. completion 2021-02-02 39 sites Stand-aloneOther conditions: Non Small Cell Lung Cancer, CancerView official trial listing → -
Terminated NCT NCT04274933
A Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor Therapy
Not yet reported AbbVie 4 participants Est. completion 2020-10-08 18 sites Stand-aloneOther conditions: Breast Cancer, CancerView official trial listing → -
Completed NCT NCT04277442
Testing Nivolumab in Combination With Decitabine and Venetoclax in Patients With Newly Diagnosed TP53 Gene Mutated Acute Myeloid Leukemia
Not yet reported National Cancer Institute (NCI) 1 participants Est. completion 2022-09-06 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Suspended NCT NCT04278768
Dose Escalation/ Expansion Study of CA-4948 as Monotherapy in Patients With Acute Myelogenous Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Not yet reported, Not yet reported Curis, Inc. 366 participants Est. completion 2026-04-01 32 sites Stand-aloneOther conditions: Acute Myelogenous Leukemia, Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT04282811
Observational Study Relapsed or Refractory Chronic Lymphocytic Leukemia Venetoclax-based Regimens Outside Clinical Trials in Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto 321 participants Est. completion 2026-10-31 27 sitesOther conditions: Chronic Lymphocytic Leukemia, Relapse Leukemia, Refractory LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04284787
BLAST MRD AML-2: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 2- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Azacitidine and Venetoclax as Frontline Therapy in Unfit Patients With Acute Myeloid Leukemia
Not yet reported National Cancer Institute (NCI) 60 participants Est. completion 2027-01-30 29 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Acute Myeloid Leukemia Post Cytotoxic Therapy, Secondary Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT04285268
Rituximab, Venetoclax, and Bortezomib for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Not yet reported Rutgers, The State University of New Jersey Est. completion 2024-09-30 1 site Stand-aloneOther conditions: High Grade B-Cell Lymphoma, Not Otherwise Specified, Recurrent Burkitt Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, Refractory Burkitt Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 RearrangementsView official trial listing → -
Completed NCT NCT04285567
A Study to Compare the Efficacy and Safety of a Combined Regimen of Venetoclax and Obinutuzumab Versus Fludarabine, Cyclophosphamide, and Rituximab (FCR)/ Bendamustine And Rituximab (BR) in FIT Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without DEL (17P) or TP53 Mutation
Not yet reported Hoffmann-La Roche 166 participants Est. completion 2025-03-19 40 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Terminated NCT NCT04298918
A Study Evaluating the Safety and Efficacy of Venetoclax in Combination With Trastuzumab Emtansine in Patients With Previously Treated HER2-Positive Locally Advanced or Metastatic Breast Cancer
Not yet reported, Not yet reported Hoffmann-La Roche 1 participants Est. completion 2021-02-04 3 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT04330820
Trial for Relapsed or Refractory AML Patients Combining Cytarabine and Mitoxantrone With Venetoclax (RELAX)
Not yet reported, Not yet reported Technische Universität Dresden 55 participants Est. completion 2025-09-24 12 sites Stand-aloneOther conditions: Relapsed Adult AML, Refractory AMLView official trial listing → -
Terminated NCT NCT04336982
A Safety and Efficacy Study of CC-90009 Combinations in Subjects With Acute Myeloid Leukemia
Not yet reported Celgene 22 participants Est. completion 2024-04-05 14 sites Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Completed NCT NCT04372433
IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML
Not yet reported Immune-Onc Therapeutics 67 participants Est. completion 2025-01-31 14 sites Stand-aloneOther conditions: AML With Monocytic Differentiation, CMMLView official trial listing → -
Active, not recruiting NCT NCT04401748
Study Of Venetoclax Tablet With Intravenous or Subcutaneous Azacitidine to Assess Change in Disease Activity In Adult Participants With Newly Diagnosed Higher-Risk Myelodysplastic Syndrome
Not yet reported AbbVie 531 participants Est. completion 2027-07 220 sites Stand-aloneOther conditions: Myelodysplastic Syndrome (MDS)View official trial listing → -
Active, not recruiting NCT NCT04416451
A Phase II Study Using Rituximab Plus Venetoclax in the Front Line Treatment of Marginal Zone Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 6 participants Est. completion 2027-06 8 sites Stand-aloneOther conditions: Marginal Zone LymphomaView official trial listing → -
Terminated NCT NCT04419389
APR-246 in Combination With Acalabrutinib or Venetoclax Based Therapy in Subjects With R/R Non Hodgkin Lymphomas (NHL)
Not yet reported, Not yet reported Aprea Therapeutics 1 participants Est. completion 2021-08-24 4 sites Stand-aloneOther conditions: Non Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Mantle Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT04419519
Assessing Minimal Residual Disease by Next- Generation Sequencing to Minimize Exposure in People With CLL or SLL Who Have Been Treated With Venetoclax
Not yet reported Memorial Sloan Kettering Cancer Center 81 participants Est. completion 2027-05 9 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)View official trial listing → -
Terminated NCT NCT04422210
A Study Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Venetoclax In Combination With Atezolizumab, Carboplatin, And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).
Not yet reported Hoffmann-La Roche 2 participants Est. completion 2020-11-06 5 sites Stand-aloneOther conditions: Small Cell Lung CancerView official trial listing → -
Completed NCT NCT04424147
Efficacy and Safety of HVA Regimens as Salvage Treatment in rrAML
Not yet reported Nanfang Hospital, Southern Medical University 96 participants Est. completion 2022-06-30 1 site Stand-aloneOther conditions: Refractory Acute Myeloid Leukemia, Relapsed Acute Erythroid Leukemia, Salvage Treatment, HVA RegimenView official trial listing → -
Terminated NCT NCT04435691
Magrolimab, Azacitidine, and Venetoclax for the Treatment of Acute Myeloid Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 110 participants Est. completion 2025-03-25 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04447716
An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment
Not yet reported Thomas Jefferson University 4 participants Est. completion 2027-03 1 site Stand-aloneOther conditions: Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Follicular Lymphoma, Recurrent Indolent Adult Non-Hodgkin Lymphoma, Recurrent Marginal Zone Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Follicular Lymphoma, Refractory Indolent Adult Non-Hodgkin Lymphoma, Refractory Marginal Zone LymphomaView official trial listing → -
Active, not recruiting NCT NCT04447768
The Combination of Venetoclax and Obinutuzumab in People With Chronic Lymphocytic Leukemia (CLL)
Not yet reported Memorial Sloan Kettering Cancer Center 100 participants Est. completion 2027-07 8 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Active, not recruiting NCT NCT04450173
Obinutuzumab, Ibrutinib, and Venetoclax for the Treatment of Previously Untreated Stage II-IV Follicular Lymphoma
Not yet reported University of California, Davis 40 participants Est. completion 2027-04 4 sites Stand-aloneOther conditions: Ann Arbor Stage II Follicular Lymphoma, Ann Arbor Stage III Follicular Lymphoma, Ann Arbor Stage IV Follicular Lymphoma, Grade 1 Follicular Lymphoma, Grade 2 Follicular Lymphoma, Grade 3a Follicular LymphomaView official trial listing → -
Status unknown NCT NCT04454580
Hypomethylating Agents and Venetoclax in Newly Diagnosed Acute Myeloid Leukemia Patients Not Eligible for Intensive Chemotherapy
Ospedale Maggiore Di Trieste 15 participants Est. completion 2020-09-30 1 siteOther conditions: Acute Myeloid Leukemia, Adult, Hypomethylating Agents, VenetoclaxView official trial listing → -
Active, not recruiting NCT NCT04476199
Venetoclax and Decitabine Assessment in Patients (≥60 - <75 Years) with Newly Diagnosed AML Eligible for Allo-SCT
Not yet reported Gruppo Italiano Trapianto di Midollo Osseo 100 participants Est. completion 2025-06-30 25 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04477291
A Study of CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDS
Not yet reported Aptose Biosciences Inc. 45 participants Est. completion 2024-04-15 10 sitesOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT04477486
Study to Assess Effect of Oral Venetoclax Tablet in Combination With Oral Ibrutinib Capsule on Best Overall Response of Complete Response in Adult Japanese Participants With Relapsed/Refractory Mantle Cell Lymphoma
Not yet reported AbbVie 13 participants Est. completion 2025-05-28 12 sites Stand-aloneOther conditions: Mantle Cell Lymphoma (MCL)View official trial listing → -
Completed NCT NCT04487106
Azacitidine, Venetoclax, and Trametinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Higher-Risk Myelodysplastic Syndrome
Not yet reported M.D. Anderson Cancer Center 21 participants Est. completion 2024-01-25 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelomonocytic Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Chronic Myelomonocytic Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Withdrawn NCT NCT04493099
Alvocidib in Combination With Decitabine and Venetoclax in Patients With Relapsed or Refractory AML or as Frontline Therapy in Unfit Patients With AML
Not yet reported, Not yet reported M.D. Anderson Cancer Center Est. completion 2020-10-12 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04501939
Cirmtuzumab Consolidation for Treatment of Patients With Detectable CLL on Venetoclax
Not yet reported University of California, San Diego 5 participants Est. completion 2026-07-22 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT04509622
A Study of Oral Venetoclax Tablet in Combination With Subcutaneous Low-Dose Cytarabine (LDAC) Injection to Assess Adverse Events in Adult Japanese Participants With Acute Myeloid Leukemia (AML)
Not yet reported AbbVie 14 participants Est. completion 2021-04-15 16 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT04512105
Pitavastatin in Combination With Venetoclax for Chronic Lymphocytic Leukemia or Acute Myeloid Leukemia
Not yet reported University of California, Irvine 6 participants Est. completion 2025-02-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia, AML, Adult, CLL, CLL, Relapsed, CLL, RefractoryView official trial listing → -
Active, not recruiting NCT NCT04515238
Sequential Regimen of Bendamustine Followed by Obinutuzumab (GA101), Zanubrutinib (BGB-3111) and Venetoclax (ABT-199) in Patients With Relapsed/Refractory CLL
Not yet reported German CLL Study Group 42 participants Est. completion 2027-02 11 sites Stand-aloneOther conditions: Chronic Lymphoid LeukemiaView official trial listing → -
Withdrawn NCT NCT04543916
Venetoclax and Irinotecan in Relapsed/Refractory SCLC
Not yet reported, Not yet reported Virginia Commonwealth University Est. completion 2028-06-30 Stand-aloneOther conditions: Relapsed Small Cell Lung Cancer, Refractory Small Cell Lung CarcinomaView official trial listing → -
Terminated NCT NCT04550442
Venetoclax and Azacitidine for the Treatment of Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 34 participants Est. completion 2026-05-29 1 site Stand-aloneOther conditions: Recurrent Chronic Myelomonocytic Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Chronic Myelomonocytic Leukemia, Refractory Myelodysplastic Syndrome, Therapy-Related Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT04553692
Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants with Relapsed, Refractory, or Newly Diagnosed Cancers
Not yet reported IGM Biosciences, Inc. 272 participants Est. completion 2025-01-20 58 sites Stand-aloneObstructive sleep apnea Other conditions: Solid Tumor, Colorectal Cancer, Non Hodgkin Lymphoma, Sarcoma, Small Lymphocytic Lymphoma, Chronic Lymphocytic Leukemia, Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04560322
Venetoclax-Obinutuzumab +/- Acalabrutinib in R/R CLL
Not yet reported Massachusetts General Hospital 40 participants Est. completion 2029-03-01 3 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Active, not recruiting NCT NCT04572763
Copanlisib Plus Venetoclax in R/R DLBCL
Not yet reported, Not yet reported Dana-Farber Cancer Institute 48 participants Est. completion 2026-07-29 3 sites Stand-aloneOther conditions: Diffuse Large B Cell Lymphoma, Relapsed Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT04589728
Prospective and Retrospective Observational Evaluation of Real World Outcome of Unfit AML Patients Treated With the Combination Venetoclax Plus Hypomethylating Agents, Under the Italian Law No.648/96
Gruppo Italiano Malattie EMatologiche dell'Adulto 202 participants Est. completion 2024-09-08 23 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT04599634
Venetoclax With Obinutuzumab and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-cell Malignancies
Not yet reported National Cancer Institute (NCI) 11 participants Est. completion 2024-06-20 1 site Stand-aloneOther conditions: Follicular Lymphoma, Marginal Zone Lymphoma, Mantle Cell Lymphoma, Chronic Lymphocytic Lymphoma, B-Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT04603001
Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations
Not yet reported Eli Lilly and Company 260 participants Est. completion 2027-05 37 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), Myeloproliferative Neoplasms (MPNs)View official trial listing → -
Withdrawn NCT NCT04607772
Study of Selinexor in Combination With Backbone Treatments or Novel Therapies In Participants With Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL)
Not yet reported, Not yet reported Karyopharm Therapeutics Inc Est. completion 2025-12 18 sites Stand-aloneOther conditions: Relapsed or Refractory Diffuse Large B-Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT04608318
Ibrutinib Monotherapy Versus Fixed-duration Venetoclax Plus Obinutuzumab Versus Fixed-duration Ibrutinib Plus Venetoclax in Patients With Previously Untreated Chronic Lymphocytic Leukaemia (CLL)
Not yet reported German CLL Study Group 897 participants Est. completion 2027-09 181 sites Stand-aloneOther conditions: Chronic Lymphoid LeukemiaView official trial listing → -
Completed NCT NCT04609826
A Study of JNJ-74856665 in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Not yet reported Janssen Research & Development, LLC 153 participants Est. completion 2025-08-25 20 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Chronic Myelomonocytic LeukemiaView official trial listing → -
Status unknown NCT NCT04613622
Pharmacokinetics of Venetoclax in Patients With Acute Myeloid Leukemia
National Taiwan University Hospital 500 participants Est. completion 2025-12-31 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT04616274
Pharmacokinetics of Venetoclax in Patients With Chronic Lymphocytic Leukemia
National Taiwan University Hospital 500 participants Est. completion 2025-12-31 1 siteOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04623541
Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome
Not yet reported, Not yet reported Genmab 194 participants Est. completion 2028-02 81 sites Stand-aloneOther conditions: Relapsed/Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Richter's Syndrome, Treatment-naïve High Risk Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04639362
CLL Induction Treatment With Venetoclax and Ibrutinib, Followed by Ibrutinib and Obinutuzumab in Patients With MRD.
Not yet reported Stichting Hemato-Oncologie voor Volwassenen Nederland 85 participants Est. completion 2028-12-01 27 sites Stand-aloneOther conditions: CLLView official trial listing → -
Terminated NCT NCT04655261
Study of Oral Venetoclax Tablets in Combination With Intravenous Obinutuzumab Injection to Assess Achievement of Best Response in Adult Participants With Chronic Lymphocytic Leukemia
AbbVie 5 participants Est. completion 2021-11-09 4 sitesOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Withdrawn NCT NCT04655391
Glasdegib-Based Treatment Combinations for the Treatment of Patients With Relapsed Acute Myeloid Leukemia Who Have Undergone Hematopoietic Cell Transplantation
Not yet reported City of Hope Medical Center Est. completion 2023-12-15 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04655755
Venetoclax in Combination With ASTX727 for the Treatment of Treatment-Naive High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 52 participants Est. completion 2028-07-20 1 site Stand-aloneOther conditions: Chronic Myelomonocytic Leukemia, Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT04657081
Pharmacokinetics, Safety, and Efficacy of ASTX727 in Combination With Venetoclax in Acute Myeloid Leukemia (AML)
Not yet reported, Not yet reported Taiho Oncology, Inc. 101 participants Est. completion 2028-12-31 34 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04659044
Polatuzumab Vedotin, Venetoclax, and Rituximab and Hyaluronidase Human for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma
Not yet reported Academic and Community Cancer Research United 3 participants Est. completion 2024-03-29 5 sites Stand-aloneOther conditions: Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3a Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Grade 1 Follicular Lymphoma, Refractory Grade 2 Follicular Lymphoma, Refractory Grade 3a Follicular Lymphoma, Refractory Mantle Cell Lymphoma, Refractory Marginal Zone Lymphoma, Refractory Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT04666649
Pegcrisantaspase in Combination With Venetoclax for Treatment of Relapsed or Refractory Acute Myeloid Leukemia (R/R AML)
Not yet reported University of Maryland, Baltimore 27 participants Est. completion 2025-05-23 1 site Stand-aloneOther conditions: Relapsed or Refractory Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT04687761
Clinical Trial to Assess the Safety and Tolerability of the Combination of Low-dose Cytarabine or Azacitidine Plus Venetoclax and Quizartinib in Newly Diagnosed AML Patients Aged Equal or More Than 60 Years Old
Not yet reported, Not yet reported PETHEMA Foundation 113 participants Est. completion 2025-05-30 15 sites Stand-aloneOther conditions: Leukemia, Myeloid, Acute, De Novo, Age More 60yrView official trial listing → -
Terminated NCT NCT04702425
VOB560-MIK665 Combination First in Human Trial in Patients With Hematological Malignancies (Relapsed/Refractory Non-Hodgkin Lymphoma, Relapsed/Refractory Acute Myeloid Leukemia, or Relapsed/Refractory Multiple Myeloma)
Not yet reported Novartis Pharmaceuticals 37 participants Est. completion 2024-07-23 9 sites Stand-aloneOther conditions: Non-Hodgkin Lymphoma (NHL), Acute Myeloid Leukemia (AML), Multiple Myeloma (MM)View official trial listing → -
Terminated NCT NCT04722601
A Dose-Finding and Efficacy Study of Venetoclax, CC-486, and Obinutuzumab in Follicular Lymphoma
Not yet reported, Not yet reported University of Chicago 2 participants Est. completion 2023-03-31 1 site Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Active, not recruiting NCT NCT04739813
Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination With Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma
Not yet reported National Cancer Institute (NCI) 34 participants Est. completion 2031-06-18 1 site Stand-aloneOther conditions: Lymphoma, Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma, Burkitt LymphomaView official trial listing → -
Active, not recruiting NCT NCT04746235
Venetoclax and ASTX727 for the Treatment of Relapsed, Refractory, or Newly Diagnosed Acute Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 85 participants Est. completion 2028-10-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04748848
A Safety, Tolerability and Preliminary Efficacy Study of CC-90011 in Combination With Venetoclax and Azacitidine in R/R Acute Myeloid Leukemia and Treatment-naïve Participants Not Eligible for Intensive Therapy
Not yet reported Celgene 1 participants Est. completion 2022-03-09 17 sites Stand-aloneOther conditions: Leukemia, MyeloidView official trial listing → -
Terminated NCT NCT04752163
DS-1594b With or Without Azacitidine, Venetoclax, or Mini-HCVD for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 17 participants Est. completion 2023-11-08 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell Neoplasm, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelomonocytic Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Chronic Myelomonocytic Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Status unknown NCT NCT04752527
Individualized Induction Therapy for Non-elderly Acute Myeloid Leukemia Patients With Adverse Risk Features
Not yet reported The First Affiliated Hospital of Soochow University 42 participants Est. completion 2022-12 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, AdultView official trial listing → -
Status unknown NCT NCT04754035
Clinical Study With Ibrutinib and Venetoclax for Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia
Not yet reported Paolo Ghia 31 participants Est. completion 2025-09-01 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT04755244
A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)
Not yet reported ALX Oncology Inc. 14 participants Est. completion 2023-08-16 5 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, AML, AdultView official trial listing → -
Active, not recruiting NCT NCT04763928
Trial in AML Secondary to MPNs Patients, Unfit for Intensive Chemotherapy, Investigating a Treatment Combination Including Decitabine and Venetoclax
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 101 participants Est. completion 2026-04 33 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04778397
Study of Magrolimab in Combination With Azacitidine Versus Physician's Choice of Venetoclax in Combination With Azacitidine or Intensive Chemotherapy in Patients With TP53 Mutant Acute Myeloid Leukemia That Have Not Been Treated
Not yet reported Gilead Sciences 258 participants Est. completion 2024-03-25 156 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04778410
Study of Magrolimab Combinations in Participants With Myeloid Malignancies
Not yet reported Gilead Sciences 54 participants Est. completion 2024-03-04 21 sites Stand-aloneOther conditions: Myeloid MalignanciesView official trial listing → -
Not yet recruiting NCT NCT04790045
Lymph Node Microenvironment Modifications in Patients With CLL Treated With Venetoclax-based Regimens
Not yet reported Paolo Ghia 30 participants Est. completion 2026-12-31Other conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT04790903
A Study Evaluating the Safety, Efficacy and Pharmacokinetics of Venetoclax in Combination With Polatuzumab Vedotin Plus Rituximab (R) and Cyclophosphamide, Doxorubicin, Prednisone (CHP) in Participants With Untreated BCL-2 Immunohistochemistry (IHC)-Positive Diffuse Large B-Cell Lymphoma (DLBCL)
Not yet reported Hoffmann-La Roche 50 participants Est. completion 2024-05-21 20 sites Stand-aloneOther conditions: Lymphoma, Large B-Cell, DiffuseView official trial listing → -
Active, not recruiting NCT NCT04801797
Venetoclax + Azacitidine vs. Induction Chemotherapy in AML
Not yet reported Massachusetts General Hospital 172 participants Est. completion 2028-01-01 9 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04802590
Study of Ibrutinib + CD20 Antibody and Venetoclax in Patients With Untreated Mantle Cell Lymphoma
Not yet reported The Lymphoma Academic Research Organisation 210 participants Est. completion 2030-03-02 45 sites Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Status unknown NCT NCT04809181
Azacitidine in Combination With Venetoclax Treatment for MRD Positive Post Allo-HSCT AML/MDS Patients
Not yet reported First Affiliated Hospital of Zhejiang University 95 participants Est. completion 2026-03-19 1 site Stand-aloneOther conditions: Hematologic Malignancy, Stem Cell Transplant ComplicationsView official trial listing → -
Completed NCT NCT04810598
Study to Assess Adverse Events and the Movement of Oral Venetoclax Tablet Through the Body of Female Participants Aged 18-75 Years With Impaired Renal Function
Not yet reported AbbVie 12 participants Est. completion 2022-08-16 2 sites Stand-aloneOther conditions: Renal Impairment, Renal DiseaseView official trial listing → -
Terminated NCT NCT04812548
A Study of Sabatolimab in Combination With Azacitidine and Venetoclax in High or Very High Risk MDS Participants
Not yet reported Novartis Pharmaceuticals 20 participants Est. completion 2023-05-08 10 sites Stand-aloneOther conditions: Myelodysplastic Syndrome (MDS)View official trial listing → -
Completed NCT NCT04813263
Study of Oral Venetoclax Tablets to Evaluate Adverse Events and Change in Disease Activity in Participants of Any Age With Acute Myeloid Leukemia
AbbVie 424 participants Est. completion 2024-04-30 281 sitesOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Active, not recruiting NCT NCT04817241
Testing Oral Decitabine and Cedazuridine (ASTX727) in Combination With Venetoclax for Higher-Risk Acute Myeloid Leukemia Patients
Not yet reported, Not yet reported National Cancer Institute (NCI) 5 participants Est. completion 2026-11-05 7 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04822766
A Study Comparing Allogeneic Hematopoietic Cell Transplantation Versus Best Available Standard of Care Therapy in Elderly Patients With Acute Myeloid Leukemia
Not yet reported Assistance Publique - Hôpitaux de Paris 24 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT04824924
A Phase 2 Study of Venetoclax in Combination With Low-dose HHT, G-CSF, and AZA as First-line Treatment for Newly Diagnosed Elderly AML Patients Unfit for Intensive Chemotherapy
Not yet reported Shanghai Jiao Tong University School of Medicine 100 participants Est. completion 2024-03 Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Completed NCT NCT04826523
Study of Oral Venetoclax Tablets to Evaluate Adverse Events and Change in Disease Activity in Participants Above 19 Years of Age With Acute Myeloid Leukemia (AML)
AbbVie 150 participants Est. completion 2025-10-20 10 sitesOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Active, not recruiting NCT NCT04843904
Safe Accelerated Venetoclax Escalation in CLL
Not yet reported Dana-Farber Cancer Institute 40 participants Est. completion 2030-06-02 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Active, not recruiting NCT NCT04847453
Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for the Treatment of Relapsed or Refractory Light Chain Amyloidosis
Not yet reported National Cancer Institute (NCI) 24 participants Est. completion 2028-06-30 16 sites Stand-aloneOther conditions: Recurrent AL Amyloidosis, Refractory AL AmyloidosisView official trial listing → -
Status unknown NCT NCT04867928
Venetoclax and Azacitidine for the Management of Molecular Relapse/Progression in Adult NPM1-mutated Acute Myeloid Leukemia
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 35 participants Est. completion 2025-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia, in Relapse, NPM1 MutationView official trial listing → -
Active, not recruiting NCT NCT04872790
Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia
Not yet reported OHSU Knight Cancer Institute 20 participants Est. completion 2027-12-02 1 site Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Mixed Phenotype Acute Leukemia, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Mixed Phenotype Acute LeukemiaView official trial listing → -
Terminated NCT NCT04874194
Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1
Not yet reported, Not yet reported M.D. Anderson Cancer Center 24 participants Est. completion 2024-09-16 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell Neoplasm, Recurrent Acute Biphenotypic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Biphenotypic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT04887857
A Study to Assess Safety and Tolerability of CC-486 (ONUREG®, Oral Azacitidine) in Combination Therapy in Participants With Acute Myeloid Leukemia (AML)
Not yet reported Celgene 6 participants Est. completion 2024-01-08 10 sites Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Active, not recruiting NCT NCT04898894
Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 37 participants Est. completion 2027-09 8 sites Stand-aloneOther conditions: Acute Leukemia of Ambiguous Lineage in Relapse, Acute Myeloid Leukemia, in Relapse, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT04904237
Aza-Ven Followed by Reduced Toxicity Conditioning Regimen (MBF) as Salvage Therapy for Refractory AML.
Not yet reported Shanghai Jiao Tong University School of Medicine 23 participants Est. completion 2024-06-01 3 sitesOther conditions: Refractory Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04905407
Tamibarotene Plus Venetoclax/Azacitidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Not yet reported Syros Pharmaceuticals 66 participants Est. completion 2024-08-12 28 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04912063
Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or IV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome
Not yet reported AbbVie 40 participants Est. completion 2023-05-09 29 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)View official trial listing → -
Completed NCT NCT04926285
Safety and Efficacy of Venetoclax With Escalating Doses of Omacetaxine in Patients With Acute Myeloid Leukemia Safety and Efficacy of Venetoclax With Escalating Doses of Omacetaxine in Patients With Acute Myeloid Leukemia (AML)
Not yet reported University of Illinois at Chicago 6 participants Est. completion 2025-02-06 1 site Stand-aloneOther conditions: Relapsed or Refractory Hematologic MalignanciesView official trial listing → -
Terminated NCT NCT04937166
A Study of Dual-SIgnaling Protein 107 (DSP107) for Patients With Hematological Malignancies
Not yet reported Kahr Medical 25 participants Est. completion 2025-10-24 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Chronic Myelomonocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04939272
Copanlisib and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma
Not yet reported, Not yet reported City of Hope Medical Center 8 participants Est. completion 2027-02-12 1 site Stand-aloneOther conditions: Recurrent Mantle Cell Lymphoma, Refractory Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT04939363
A Study to Evaluate Efficacy & Safety of Obinutuzumab, Ibrutinib, and Venetoclax in Richter's Syndrome;
Not yet reported Bnai Zion Medical Center 12 participants Est. completion 2024-12-04 4 sites Stand-aloneOther conditions: Richter's SyndromeView official trial listing → -
Terminated NCT NCT04964505
Uproleselan, Azacitidine, and Venetoclax for the Treatment of Treatment Naive Acute Myeloid Leukemia
Not yet reported Brian Jonas 16 participants Est. completion 2025-10-07 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04965493
A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Not yet reported Loxo Oncology, Inc. 600 participants Est. completion 2027-10 176 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Active, not recruiting NCT NCT04968015
Venetoclax + Cytarabine Versus Idarubicin + Cytarabine : Efficacity Assessment as Post-remission Therapy to Elderly Patients With Acute Myeloid Leukemia in First Remission
Not yet reported French Innovative Leukemia Organisation 134 participants Est. completion 2029-01-31 26 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT04973618
Study of APVO436 in Elderly or Unfit Patients With Newly Diagnosed AML
Not yet reported Aptevo Therapeutics Est. completion 2027-01Other conditions: AMLView official trial listing → -
Active, not recruiting NCT NCT04975919
Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 20 participants Est. completion 2027-05-31 1 site Stand-aloneOther conditions: Recurrent Acute Biphenotypic Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Biphenotypic Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT04981912
Rituximab + High-Dose Methylprednisolone Debulking Prior to Venetoclax for CLL & SLL Patients
Not yet reported University of California, San Diego 4 participants Est. completion 2025-07-31 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaView official trial listing → -
Withdrawn NCT NCT04990778
Venetoclax and Eprenetapopt for the Treatment of Relapsed of Refractory Mantle Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center Est. completion 2023-03-24 1 site Stand-aloneOther conditions: Recurrent Mantle Cell Lymphoma, Refractory Mantle Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT05001828
Study of ADI-PEG 20, Venetoclax and Azacitidine in Acute Myeloid Leukemia
Not yet reported Polaris Group 38 participants Est. completion 2027-01 3 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, AdultView official trial listing → -
Status unknown NCT NCT05005299
Venetoclax in Combination With Non-myeloablative Conditioning Allogeneic Haematopoietic Stem Cell Transplantation
Not yet reported Melbourne Health 18 participants Est. completion 2026-03-31 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Leukemia, Lymphoblastic, Acute, L1, Leukemia, Lymphoblastic, Acute, L2, Myelodysplastic Syndromes, Non-hodgkin Lymphoma, Plasma Cell MyelomaView official trial listing → -
Active, not recruiting NCT NCT05016947
Venetoclax Plus Inotuzumab for B-ALL
Not yet reported Dana-Farber Cancer Institute 23 participants Est. completion 2026-12-23 2 sites Stand-aloneOther conditions: B-cell Acute Lymphoblastic Leukemia, B-Cell Lymphoma, ALLView official trial listing → -
Terminated NCT NCT05025423
Phase II Trial of Venetoclax and Rituximab as Initial Therapy in Older Patients With Mantle Cell Lymphoma
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 7 participants Est. completion 2025-05-14 1 site Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT05048615
Low-dose Venetoclax and Azacitidine as Front-line Therapy in Newly Diagnosed AML
Not yet reported Hospital Universitario Dr. Jose E. Gonzalez 15 participants Est. completion 2023-01-20 1 site Stand-aloneOther conditions: AMLView official trial listing → -
Status unknown NCT NCT05053425
Bcl-2 Inhibitors Combined With Azacytidine and Chemotherapy in Elderly Patients With Previously Untreated AML
Not yet reported LanZhou University 30 participants Est. completion 2023-03-18 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05053659
Loncastuximab Tesirine and Venetoclax for Relapsed/ Refractory Non-Hodgkin Lymphoma
Not yet reported Paolo Caimi, MD 23 participants Est. completion 2026-11 1 site Stand-aloneOther conditions: Relapsed Non Hodgkin Lymphoma, Refractory Non-Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT05054465
A Phase 1b-2 Trial to Assess Venetoclax and Navitoclax Consolidation and Post-transplant Maintenance in High-risk Patients With T-ALL
Not yet reported, Not yet reported Israeli Medical Association 48 participants Est. completion 2026-08-01 6 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05057494
A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported AstraZeneca 607 participants Est. completion 2029-04-10 37 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaView official trial listing → -
Active, not recruiting NCT NCT05069051
Belimumab in Patients with Chronic Lymphocytic Leukemia
Not yet reported University Hospital Tuebingen 120 participants Est. completion 2027-07-14 1 site Stand-aloneOther conditions: Chronic Lymphoid Leukemia in RelapseView official trial listing → -
Terminated NCT NCT05079230
Study of Magrolimab Versus Placebo in Combination With Venetoclax and Azacitidine in Participants With Acute Myeloid Leukemia
Not yet reported Gilead Sciences 378 participants Est. completion 2024-04-11 164 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05084027
Venetoclax Combining With Fludarabine and Melphalan as Conditioning Regimen for Allo-HSCT
Not yet reported First Affiliated Hospital of Zhejiang University 50 participants Est. completion 2024-09-30 8 sites Stand-aloneOther conditions: Hematologic Malignancy, Older Patients, Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT05105841
Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax in Combination With Intravenous (IV) Obinutuzumab or Oral Ibrutinib in Adult Participants With Untreated Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
Not yet reported AbbVie 20 participants Est. completion 2025-10-09 20 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)View official trial listing → -
Terminated NCT NCT05107856
PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignancies
Not yet reported Prelude Therapeutics Incorporated 21 participants Est. completion 2024-01-19 9 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, B-cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Chronic Myelomonocytic Leukemia, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Myelodysplastic Syndromes, Myeloproliferative Neoplasm, Small Lymphocytic LymphomaView official trial listing → -
Active, not recruiting NCT NCT05144243
Study to Assess Adverse Events and Change in Disease State of Oral Venetoclax in Combination With Subcutaneous (SC) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Intensive Chemotherapy in China
Not yet reported AbbVie 44 participants Est. completion 2026-03 18 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT05149378
Venetoclax Based Regimen for R/R T-ALL
Not yet reported The First Affiliated Hospital of Soochow University 25 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Acute T-Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT05155709
A Study of Siremadlin in Combination With Venetoclax Plus Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Chemotherapy.
Not yet reported Novartis Pharmaceuticals 14 participants Est. completion 2024-04-17 10 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05157971
Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia
Not yet reported City of Hope Medical Center 24 participants Est. completion 2027-04-12 1 site Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, Ph-Like Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT05168202
A Study to Assess the Effect of CC-95251 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndromes
Not yet reported Bristol-Myers Squibb 56 participants Est. completion 2024-07-30 32 sites Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Myelodysplastic SyndromesView official trial listing → -
Active, not recruiting NCT NCT05177731
Venetoclax + Decitabine vs. "7+3" Induction Chemotherapy in Young AML
Not yet reported Chen Suning 188 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: AML, Adult, Chemotherapy EffectView official trial listing → -
Active, not recruiting NCT NCT05182385
Venetoclax in Addition to Blinatumomab in Adult Patients With Relapsed/Refractory B Cell Precursor Acute Lymphoblastic Leukemia Relapsed/Refractory B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)
Not yet reported, Not yet reported Goethe University 30 participants Est. completion 2026-04-30 17 sites Stand-aloneOther conditions: ALL, Recurrent, AdultView official trial listing → -
Completed NCT NCT05190549
CAV Regimen Bridging to HSCT for R/R AL
Not yet reported The First Affiliated Hospital of Soochow University 30 participants Est. completion 2024-11-17 1 siteOther conditions: Acute Leukemia, Relapsed, Acute Leukemia RefractoryView official trial listing → -
Active, not recruiting NCT NCT05192889
Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax
Not yet reported, Not yet reported St. Jude Children's Research Hospital 35 participants Est. completion 2027-02 2 sites Stand-aloneOther conditions: Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05201066
Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab.
Not yet reported Novartis Pharmaceuticals 33 participants Est. completion 2028-02-14 24 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, Leukemia, Myelomonocytic, ChronicView official trial listing → -
Terminated NCT NCT05209152
AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia
Not yet reported Amgen 7 participants Est. completion 2023-12-19 1 site Stand-aloneOther conditions: Higher Risk Myelodysplastic Syndrome, Chronic Myelomonocytic LeukemiaView official trial listing → -
Withdrawn NCT NCT05209308
Rituximab Plus Venetoclax in Combination With Zandelisib in Subjects With CLL
Not yet reported MEI Pharma, Inc. Est. completion 2023-03-15 4 sites Stand-aloneOther conditions: CLLView official trial listing → -
Active, not recruiting NCT NCT05211336
Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma Involving the Central Nervous System
Not yet reported National Cancer Institute (NCI) 14 participants Est. completion 2029-06-01 1 site Stand-aloneOther conditions: Primary Diffuse Large B-cell Lymphoma of the Central Nervous System (CNS), Aggressive B-cell Lymphoma With Secondary Involvement of the CNSView official trial listing → -
No Longer Available NCT NCT05215405
Expanded Access Program of Venetoclax and Navitoclax for Pediatric Patients with Relapsed or Refractory ALL or LL
Kathleen Ludwig 1 siteOther conditions: Relapsed Childhood ALL, Relapsed Childhood Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT05215639
A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy in Switzerland and Austria Receiving Oral Venetoclax Tablets
AbbVie 120 participants Est. completion 2025-11-24 19 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05222984
Navitoclax, Venetoclax, and Decitabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Previously Treated With Venetoclax
Not yet reported City of Hope Medical Center 17 participants Est. completion 2027-03-02 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05226455
Venetoclax in Patients With MDS or AML in Relapse After AHSCT
Not yet reported, Not yet reported Groupe Francophone des Myelodysplasies 55 participants Est. completion 2027-09-01 11 sites Stand-aloneOther conditions: MDS, AMLView official trial listing → -
Status unknown NCT NCT05262465
Microtransplantation Combined With Azacytidine to Improve the Efficacy of EAML
Not yet reported guomei 300 participants Est. completion 2025-07-01 1 site Stand-aloneOther conditions: Adult Acute Myeloid LeukemiaView official trial listing → -
Suspended NCT NCT05263284
8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported City of Hope Medical Center 30 participants Est. completion 2029-01-25 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05264883
Venetoclax+HMA+Aclarubicin Versus Venetoclax+HMA in Treatment-Naive Elderly Patients With AML
Not yet reported The First Affiliated Hospital with Nanjing Medical University 170 participants Est. completion 2025-02-28 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT05268003
A Phase II Study of the Combination of Ponatinib With Mini-hyper CVD Chemotherapy and Venetoclax in Patients With Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2026-04-21 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, LeukemiaView official trial listing → -
Terminated NCT NCT05275439
Phase 1 Study of Shattuck Labs (SL)-172154 in Subjects With MDS or AML
Not yet reported Shattuck Labs, Inc. 106 participants Est. completion 2025-02-06 23 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT05282719
Clinical Study of Venetoclax Combined With Azacytiside in the Treatment of Myelodysplastic/Myeloproliferative Neoplasms in Adults
Not yet reported The First Affiliated Hospital of Soochow University 33 participants Est. completion 2023-02 1 site Stand-aloneOther conditions: Myelodysplastic/Myeloproliferative Neoplasms, AdultView official trial listing → -
Active, not recruiting NCT NCT05283720
A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma
Not yet reported Genmab 264 participants Est. completion 2032-11 76 sitesOther conditions: Non-Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT05312112
Real World Outcomes Using Novel Agents for AML in the UK
Guy's and St Thomas' NHS Foundation Trust 1000 participants Est. completion 2023-10-01 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT05317494
A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy Receiving Oral Venetoclax Tablets in Greece
AbbVie 106 participants Est. completion 2026-05-29 13 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT05317936
Pirtobrutinib (LOXO-305) Consolidation for MRD Eradication in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL) Treated With Venetoclax
Not yet reported, Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2025-10-06 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Active, not recruiting NCT NCT05356169
Intensive Therapy Combined With Venetoclax for Adult Acute Myeloid Leukemia
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 312 participants Est. completion 2027-10-15 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT05361057
Efficacy of Venetoclax Based Regimen in Prevention Relapse of Consecutive MRD Positive AML Patients
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 20 participants Est. completion 2024-01-23 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Measurable DiseaseView official trial listing → -
Status unknown NCT NCT05362942
Combination of Venetoclax, Hypomethylation Agent and Low-dose Cytarabine as a Salvage Therapy for Acute Myeloid Leukemia
Not yet reported Beijing 302 Hospital 52 participants Est. completion 2024-04-30 Stand-aloneOther conditions: Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Minimal Residual DiseaseView official trial listing → -
Withdrawn NCT NCT05367401
A Study of Sabatolimab and Magrolimab-based Treatment in AML or Higher Risk MDS Participants
Not yet reported, Not yet reported Novartis Pharmaceuticals Est. completion 2029-10-26 Stand-aloneOther conditions: Myelodysplastic Syndromes, Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT05371054
Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid Malignancies
Not yet reported, Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2025-12-16 1 site Stand-aloneOther conditions: Lymphoma, Non-Hodgkin Lymphoma, NHL, Hematologic Malignancies, Lymphoid MalignanciesView official trial listing → -
Active, not recruiting NCT NCT05379166
Venetoclax and Azacitidine for Treatment of Therapy Related or Secondary Myelodysplastic Syndrome
Not yet reported Uma Borate 33 participants Est. completion 2026-12-15 3 sites Stand-aloneOther conditions: Secondary Myelodysplastic Syndrome, Therapy-Related Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT05386576
A Study of Venetoclax in Combination With Chemotherapy to Treat Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)
Not yet reported Memorial Sloan Kettering Cancer Center 12 participants Est. completion 2027-05 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05388006
Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported Mayo Clinic 27 participants Est. completion 2031-03-30 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Richter Syndrome, Small Lymphocytic LymphomaView official trial listing → -
Active, not recruiting NCT NCT05391750
Venetoclax and Tocilizumab for the Treatment of Patients With Relapsed or Refractory t(11;14) Multiple Myeloma
Not yet reported Emory University 7 participants Est. completion 2028-02-12 1 site Stand-aloneOther conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell MyelomaView official trial listing → -
Terminated NCT NCT05424562
A Study to Assess Change in Disease State in Adult Participants With Acute Myeloid Leukemia (AML) Ineligible for Intensive Chemotherapy Receiving Oral Venetoclax Tablets in Canada
AbbVie 210 participants Est. completion 2026-08-31 20 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05428969
A Study to Assess Safety, Tolerability and Preliminary Efficacy of Bexmarilimab in Combination With Standard of Care in Patients With Hematological Malignancies
Not yet reported, Not yet reported Faron Pharmaceuticals Ltd 181 participants Est. completion 2027-03 10 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Relapsed/Refractory AMLView official trial listing → -
Completed NCT NCT05433532
Study of Azacitidine,Venetoclax,and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients
Not yet reported The First Affiliated Hospital of Soochow University 20 participants Est. completion 2024-04-13 1 site Stand-aloneOther conditions: Philadelphia Chromosome, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia, Mixed Phenotype Acute LeukemiaView official trial listing → -
Status unknown NCT NCT05448599
A Clinical Study of 6MW3211 Monotherapy or Combination Therapy for AML or MDS
Not yet reported, Not yet reported Mabwell (Shanghai) Bioscience Co., Ltd. 120 participants Est. completion 2024-10 1 siteOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT05451771
Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis
Not yet reported, Not yet reported Columbia University 53 participants Est. completion 2027-09 4 sites Stand-aloneOther conditions: AL AmyloidosisView official trial listing → -
Active, not recruiting NCT NCT05453903
A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies
Not yet reported Janssen Research & Development, LLC 196 participants Est. completion 2027-06-30 32 sites Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Active, not recruiting NCT NCT05455294
Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms
Not yet reported Jacqueline Garcia, MD 16 participants Est. completion 2026-12-31 3 sites Stand-aloneOther conditions: Myeloid Malignancy, Myelodysplastic Syndromes, Myelofibrosis, Acute Myeloid Leukemia, Myeloproliferative NeoplasmView official trial listing → -
Completed NCT NCT05456048
Influence of Molecular Abnormalities on Response of VAH vs. VEN+HMA in RR-AML
Nanfang Hospital, Southern Medical University 231 participants Est. completion 2022-05-31 1 siteOther conditions: Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Gene Abnormality, Cytogenetic AbnormalityView official trial listing → -
Status unknown NCT NCT05457361
VAH Versus VA for Salvage Therapy of R/R-AML
Not yet reported Nanfang Hospital, Southern Medical University 162 participants Est. completion 2023-12-31 1 siteOther conditions: Venetoclax Combined With Azacitidine Plus Homoharringtonine, Venetoclax Combined With AzacitidineView official trial listing → -
Terminated NCT NCT05464836
Phase II Study to Evaluate Safety and Efficacy of CB-103 With Venetoclax in Adolescent and Young Adult Patients With Relapsed/Refractory T-ALL or T-LBL
Not yet reported M.D. Anderson Cancer Center 2 participants Est. completion 2024-08-12 1 site Stand-aloneOther conditions: Leukemia, Lymphoblastic, LeukemiaView official trial listing → -
Completed NCT NCT05471700
Single Arm Study of Azacitidine and Venetoclax for Treatment of Newly Diagnosed Fit Acute Myeloid Leukemia Patients
Not yet reported Zhujiang Hospital 40 participants Est. completion 2023-04-04 1 site Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Active, not recruiting NCT NCT05478512
Front-line VenObi Combination Followed by Ven or VenZan Combination in Patients With Residual Disease: a MRD Tailored Treatment for Young Patients With High-risk CLL
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 78 participants Est. completion 2027-07 8 sites Stand-aloneOther conditions: High Risk CLL, Chronic Lymphocytic LeukemiaView official trial listing → -
Withdrawn NCT NCT05486481
Venetoclax, Daratumumab, and Dexamethasone for Systemic Light-Chain Amyloidosis With Translocation (11;14) (ALTITUDE)
Not yet reported, Not yet reported Alfred Chung, MD Est. completion 2028-12-31 Stand-aloneOther conditions: AL Amyloidosis, Light Chain (AL) Amyloidosis, Systemic Light Chain DiseaseView official trial listing → -
Status unknown NCT NCT05503355
A Phase I/II Dose Escalation and Expansion Study of BST-236 Plus Venetoclax in Patients With Unfit Newly Diagnosed AML
Not yet reported, Not yet reported BioSight Ltd. 80 participants Est. completion 2025-12-01 3 sites Stand-aloneOther conditions: AML, AdultView official trial listing → -
Status unknown NCT NCT05513131
Clinical Study Protocol of Venetoclax Combined With Azacitidine and Harringtonine in the Treatment of sAML
Not yet reported The First Affiliated Hospital with Nanjing Medical University 30 participants Est. completion 2025-09-30 1 site Stand-aloneOther conditions: Secondary Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05520567
A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid Leukemia
Not yet reported, Not yet reported Astellas Pharma Global Development, Inc. 70 participants Est. completion 2028-07-31 18 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), FLT3-mutated Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05522192
Clinical Study of Mitoxantrone Hydrochloride Liposome Injection in Subjects With Acute Myeloid Leukemia
Not yet reported, Not yet reported Hui Zeng 70 participants Est. completion 2026-05 1 site Stand-aloneOther conditions: Relapsed or Refractory Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT05528354
Venetoclax and Decitabin Based Conditioning Regimen Followed With Post-HSCT Decitabin Maintenance Therapy in TP53 Mutant AML/MDS Patients
Not yet reported Zhejiang University 58 participants Est. completion 2026-03-31 4 sites Stand-aloneOther conditions: Hematopoietic Stem Cell Transplantation, TP53View official trial listing → -
Status unknown NCT NCT05546060
Efficacy and Safety of Venetoclax Combined With Dexamethasone and Etoposide in HLH
Not yet reported Beijing Friendship Hospital 20 participants Est. completion 2025-10-01 1 site Stand-aloneOther conditions: Hemophagocytic LymphohistiocytosisView official trial listing → -
Not yet recruiting NCT NCT05554419
Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)
Not yet reported National Cancer Institute (NCI) 184 participants Est. completion 2030-12-31 Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Acute Myeloid Leukemia Arising From Previous Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy, Secondary Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT05555979
A Study to Assess Change in Patient Experience in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Venetoclax Tablets + Intravenous Rituximab or Bruton's Tyrosine Kinase Inhibitors Tablets in the United Kingdom
AbbVie 56 participants Est. completion 2024-04-10 10 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT05564650
Navitoclax in Relapsed or Refractory High-Risk Myelodysplastic Syndrome
Not yet reported Thomas Jefferson University 6 participants Est. completion 2026-05-08 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, Recurrent Myelodysplastic Syndrome, Refractory Myelodysplastic SyndromeView official trial listing → -
Status unknown NCT NCT05576532
Venetoclax Plus IM2 Regimen for Relapsed and Refractory T Lymphoblastic Lymphoma/Leukemia
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 30 participants Est. completion 2025-10-10 1 siteOther conditions: T-lymphoblastic Lymphoma, Relapsed Disease, Refractory Lymphoma, Refractory Leukemia, Safety, Efficacy, SelfView official trial listing → -
Status unknown NCT NCT05583175
Venetoclax Plus RIC Regimen Allo-HSCT for Elderly Patients With High-risk Myeloid Malignancies
Not yet reported Xianmin Song, MD 50 participants Est. completion 2024-11-01 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, MDS, Hematopoietic Stem Cell Transplantation, Myeloid MalignancyView official trial listing → -
Completed NCT NCT05594784
Olverembatinib Combined With Reduced-Intensity Chemotherapy and Venetoclax for de Novo Ph+ ALL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 79 participants Est. completion 2025-03-25 1 site Stand-aloneOther conditions: Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05600894
Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm
Not yet reported National Cancer Institute (NCI) 132 participants Est. completion 2027-08-31 34 sites Stand-aloneOther conditions: Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts, Myelodysplastic/Myeloproliferative Neoplasm, Myeloproliferative NeoplasmView official trial listing → -
Terminated NCT NCT05618366
Tazemetostat and Venetoclax in Relapsed/Refractory Non-Hodgkin Lymphoma
Not yet reported Weill Medical College of Cornell University 3 participants Est. completion 2026-02-27 1 site Stand-aloneOther conditions: Lymphoma, Non-Hodgkin, Diffuse Large B Cell Lymphoma, Follicular LymphomaView official trial listing → -
Not yet recruiting NCT NCT05628623
Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia (AML) Following Initial Treatment
Not yet reported Eastern Cooperative Oncology Group 184 participants Est. completion 2027-02 Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Active, not recruiting NCT NCT05650723
Zanubrutinib and Venetoclax as Initial Therapy for Chronic Lymphocytic Leukemia (CLL) With Response-based Obinutuzumab
Not yet reported Weill Medical College of Cornell University 50 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Completed NCT NCT05654194
Azacitidine Combined With Venetoclax and ATRA in Newly Diagnosed AML
Not yet reported The First Affiliated Hospital of Soochow University 60 participants Est. completion 2026-02-28 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT05659992
Clinical Study of Venetoclax Combined with CACAG Regimen in the Treatment of Newly Diagnosed Acute Myeloid Leukemia
Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2024-08-14 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT05662956
A Clinical Study of VA-CAG as Induction Therapy in Newly Diagnosed AML Patients
Not yet reported Hematology department of the 920th hospital 114 participants Est. completion 2025-04-30 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT05665530
A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies
Not yet reported Prelude Therapeutics Incorporated 86 participants Est. completion 2026-01-21 24 sites Stand-aloneOther conditions: Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Mantle Cell Lymphoma (MCL), Richter's Syndrome, T-cell Lymphoma, Diffuse Large B-cell Lymphoma (DLBCL), Marginal Zone Lymphoma, Myeloid Malignancies, Acute Myeloid Leukemia (AML), Chronic Myelomonocytic Leukemia (CMML), Myelodysplastic Syndrome (MDS), MDS/Myeloproliferative Neoplasm (MPN) Overlap SyndromeView official trial listing → -
Completed NCT NCT05673057
Study of MP0533 in Patients Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported Molecular Partners AG 80 participants Est. completion 2026-09-14 9 sites Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Newly DiagnosedView official trial listing → -
Active, not recruiting NCT NCT05677919
Pirtobrutinib and Venetoclax With MRD Detection for Previously Untreated Chronic Lymphocytic Leukemia
Not yet reported Mayo Clinic 72 participants Est. completion 2030-09-03 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT05701215
Venetoclax After TKI to Target Persisting Stem Cells in CML
Not yet reported Thomas Ernst, PD Dr. med. 10 participants Est. completion 2026-05-31 2 sites Stand-aloneOther conditions: Chronic Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05734495
Pirtobrutinib and Venetoclax in Waldenström Macroglobulinemia
Not yet reported Dana-Farber Cancer Institute 46 participants Est. completion 2033-01-25 2 sites Stand-aloneOther conditions: Waldenstrom MacroglobulinemiaView official trial listing → -
Withdrawn NCT NCT05740449
HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Not yet reported, Not yet reported Princess Maxima Center for Pediatric Oncology Est. completion 2029-10-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) RefractoryView official trial listing → -
Active, not recruiting NCT NCT05753501
Study to Evaluate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants With B-Cell Malignancies
Not yet reported AbbVie 135 participants Est. completion 2031-03 51 sites Stand-aloneOther conditions: Hematologic CancerView official trial listing → -
Withdrawn NCT NCT05766514
Trial of Cladribine and Low-Dose Cytarabine (LoDAC) Alternating With Decitabine vs. Hypomethylating Agents (HMA) Plus Venetoclax as Frontline Therapy for AML or High-Grade MDS in Patients Unfit for Intensive Induction
Not yet reported University of Florida Est. completion 2030-12 1 siteOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Active, not recruiting NCT NCT05768711
Azacitidine Combined With Venetoclax in Patients With Higher-risk Chronic Myelomonocytic Leukemia (AVENHIR)
Not yet reported Groupe Francophone des Myelodysplasies 44 participants Est. completion 2028-10 24 sites Stand-aloneOther conditions: Chronic Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT05774886
Implantable Microdevice for TNBC - Pilot Study
Not yet reported Dana-Farber Cancer Institute Est. completion 2028-09-01 Stand-aloneOther conditions: Triple Negative Breast Cancer, Breast Cancer Stage II, Breast Cancer Stage III, Breast Cancer, Early Stage Triple-Negative Breast Carcinoma, Breast Neoplasms, Breast CarcinomaView official trial listing → -
Terminated NCT NCT05780879
A Proof of Concept Pilot Study of the Addition of Venetoclax to Standard Remission Induction Chemotherapy Fludarabine or Cladrabine, Cytarabine, and Granulocyte Colony Stimulating Factor (G-CSF) (FLAG or CLAG) for Frontline Therapy of Secondary Acute Myeloid Leukemia
Not yet reported University of Michigan Rogel Cancer Center 10 participants Est. completion 2025-08-16 1 site Stand-aloneOther conditions: Secondary Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05782127
Oral Azacitidine Combined With Venetoclax in Previously Untreated Higher-risk Myelodysplastic Syndromes
Not yet reported, Not yet reported Groupe Francophone des Myelodysplasies 36 participants Est. completion 2028-11 25 sites Stand-aloneOther conditions: Untreated Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT05799079
Decitabine and Cedazuridine in Combination With Venetoclax for the Treatment of Patients Who Have Relapsed Acute Myeloid Leukemia After Donor Stem Cell Transplant
Not yet reported Sanjay Mohan 1 participants Est. completion 2024-09-20 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05807347
Venetoclax Combined With Azacitidine and CAG in Refractory/Relapse Acute Myeloid Leukemia
Not yet reported Hematology department of the 920th hospital 42 participants Est. completion 2026-02-01 1 site Stand-aloneOther conditions: Refractory/Relapse Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05809167
Venetoclax+Azacytidine+Modified BUCY Conditioning Regimen for Acute Lymphoblastic Leukemia Undergoing Allo-HSCT
Not yet reported The First Affiliated Hospital of Soochow University 55 participants Est. completion 2026-01-20 1 site Stand-aloneOther conditions: Allogeneic Hematopoietic Stem Cell Transplantation, Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT05823714
Venetoclax+Azacytidine+Modified BUCY Conditioning Regimen for Acute Myeloid Leukemia and Myelodysplastic Syndromes Undergoing Allo-HSCT
Not yet reported The First Affiliated Hospital of Soochow University 70 participants Est. completion 2026-01-20 1 site Stand-aloneOther conditions: Allogeneic Hematopoietic Stem Cell Transplantation, Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT05829226
A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)
Not yet reported PureTech 101 participants Est. completion 2025-12-31 9 sites Stand-aloneOther conditions: AML, Adult Recurrent, MDSView official trial listing → -
Active, not recruiting NCT NCT05833438
Venetoclax in Combination With 5 Days Azacitidine in Untreated AML Patients, Not Eligible for Standard Induction Therapy
Not yet reported University of Leipzig 45 participants Est. completion 2026-05 10 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Status unknown NCT NCT05841771
Hypomethylating Agent and Venetoclax After Allo-HSCT in Patients With High-risk Myeloid Malignancies.
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 78 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Hypomethylating Agent, Venetoclax, Myeloid MalignancyView official trial listing → -
Status unknown NCT NCT05863845
Efficacy and Safety of Venetoclax Combined With BEAM Pretreatment in Autologous Transplantation for DLBCL
Not yet reported Ruijin Hospital 52 participants Est. completion 2025-11-30 Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT05864742
Genetically Risk-Stratified Venetoclax, Ibrutinib, Rituximab (± Navitoclax) in Relapsed/Refractory Mantle Cell Lymphoma
Not yet reported Peter MacCallum Cancer Centre, Australia 40 participants Est. completion 2029-06-01 3 sites Stand-aloneOther conditions: Mantle Cell Lymphoma RefractoryView official trial listing → -
Status unknown NCT NCT05893472
A Study on the Efficacy and Safety of Venetoclax Combined With HAA Regimen in Newly Diagnosed Young AML.
Not yet reported, Not yet reported ZePing Zhou 45 participants Est. completion 2024-04-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, VenetoclaxView official trial listing → -
Completed NCT NCT05909553
Study to Assess Adverse Events and Compare How Crushed, Ground, and Intact Oral Tablets Venetoclax Moves Through the Body of Healthy Female Adult Volunteers
Not yet reported AbbVie 15 participants Est. completion 2023-09-22 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT05918198
Clinical Study of Venetoclax Combined With CAG in the Treatment of Refractory/Relapsed Acute Myeloid Leukemia
Not yet reported Peking University People's Hospital 52 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT05941585
Mitoxantrone Hydrochloride Liposome Combined With Chemotherapy in Untreated de Novo Acute Myeloid Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 60 participants Est. completion 2025-01-17 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05949762
Safety and Efficacy of Venetoclax in Combination With Azacitidine and HA Regimen in the Treatment of AML in the Elderly
Not yet reported, Not yet reported ZePing Zhou 45 participants Est. completion 2024-04-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05951959
A Study of Acalabrutinib Plus Venetoclax and Rituximab in Participants With Treatment Naïve Mantle Cell Lymphoma
Not yet reported AstraZeneca 108 participants Est. completion 2028-10-31 29 sites Stand-aloneOther conditions: Mantle Cell Lymphoma (MCL)View official trial listing → -
Active, not recruiting NCT NCT05963074
A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia
Not yet reported Janssen Research & Development, LLC 333 participants Est. completion 2029-03-19 74 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-Cell, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT05976217
Safety and Efficacy of Venetoclax in Idiopathic Pulmonary Fibrosis
Not yet reported University of Alabama at Birmingham 3 participants Est. completion 2024-03-20 2 sites Stand-aloneOther conditions: Idiopathic Pulmonary FibrosisView official trial listing → -
Active, not recruiting NCT NCT05996406
Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis with Translocation (11;14)
Not yet reported Peking Union Medical College Hospital 36 participants Est. completion 2025-09 1 site Stand-aloneOther conditions: Light Chain (AL) Amyloidosis, CCND1 Translocation, VenetoclaxView official trial listing → -
Withdrawn NCT NCT06007911
Venetoclax-Navitoclax With Cladribine-based Salvage Therapy in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Medical College of Wisconsin Est. completion 2027-04 1 site Stand-aloneOther conditions: Relapsed Adult AML, Refractory AMLView official trial listing → -
Completed NCT NCT06030089
Plasma Dosage of Venetoclax in the Fup of AML Patients Treated With Aza + Ven
Not yet reported Centre Hospitalier Universitaire de Nice 20 participants Est. completion 2025-03-03 2 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT06042725
MC210808 Venetoclax in Combination With Lenalidomide and Dexamethasone (Ven-Rd), Daratumumab and Dexamethasone (Ven-Dd), or Daratumumab-Lenalidomide-Dexamethasone (Ven-DRd) for the Treatment of Multiple Myeloma
Not yet reported Mayo Clinic 16 participants Est. completion 2027-05-29 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT06046313
Prolonged Ultra Low-dose Decitabine Plus Venetoclax for Primary Diagnosed Elderly AMLK/MDS
Not yet reported First Affiliated Hospital of Zhejiang University 120 participants Est. completion 2026-10-19 1 siteOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Not yet recruiting NCT NCT06050941
Reduced Intensive Idarubicin and Cytarabine Plus Venetoclax as First-line Treatment for Adults AML and MDS
Not yet reported First Affiliated Hospital of Zhejiang University 60 participants Est. completion 2027-04-02 Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Suspended NCT NCT06055621
Evaluation of DASATINIB Monotherapy Efficacy in Acute Myeloid Leukemia Patients Refractory to VENETOCLAX-AZACITIDINE
Not yet reported Institut Paoli-Calmettes 35 participants Est. completion 2029-01 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT06058741
A Study to Asses Effectiveness and Treatment Management of Oral Venetoclax Tablets + Subcutaneously Injected Azacitidine in Adult Participants Ineligible for Intensive Chemotherapy With de Novo Acute Myeloid Leukemia (AML) in Italy
AbbVie 151 participants Est. completion 2026-07-21 28 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT06066242
Optimizing Induction Chemotherapy Regimens for ND Elderly AML Patients Who Are Eligible for Intense Chemotherapy
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 113 participants Est. completion 2028-05-10 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT06068621
Venetoclax Plus CACAG Regimen for Newly Diagnosed Acute Myeloid Leukemia
Not yet reported Chinese PLA General Hospital 200 participants Est. completion 2025-08-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT06070948
A Study to Assess Food Effect of Venetoclax New Tablet Formulation in Healthy Female Participants
Not yet reported AbbVie Est. completion 2025-07-28 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT06073730
Comparison of the Efficacy and Safety of Venetoclax in Combination With 3 Days Decitabine (DEC3-VEN) vs. Venetoclax in Combination With Azacitidine (VIALE-A) in the Treatment of Elderly Patients or Unfit, New-diagnosis Acute Myeloid Leukemia Patients
Not yet reported The Second Affiliated Hospital of Kunming Medical University 154 participants Est. completion 2026-04-30 1 site Stand-aloneOther conditions: Elderly AML Patients, Unfit, New-diagnosis AML, Acute Myeloid Leukemia, Venetoclax, DecitabineView official trial listing → -
Active, not recruiting NCT NCT06073821
Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)
Not yet reported BeOne Medicines 652 participants Est. completion 2032-12 201 sitesOther conditions: CLLView official trial listing → -
Status unknown NCT NCT06078306
CD19CD22 CAR-T Therapy in Patients With High-Risk B Acute Lymphoblastic Leukemia (B-ALL).
Not yet reported The First Affiliated Hospital of Soochow University 20 participants Est. completion 2025-09-10 1 site Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, Ph-Negative ALL, High Risk Acute Lymphoblastic LeukemiaView official trial listing → -
Withdrawn NCT NCT06085638
Phase I/II Study of SY-1425 (Tamibarotene) in Combination With Azacitidine and Venetoclax for Patients With Chronic Myelomonocytic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center Est. completion 2023-10-20 Stand-aloneOther conditions: Chronic Myelomonocytic LeukemiaView official trial listing → -
Status unknown NCT NCT06087419
A Prospective Clinical Study of Bridging alloHSCT After Treatment With Obinutuzumab in Combination With Chidamide and Venetoclax in RR Ph-ALL and B-cell Lymphoma Patients
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 42 participants Est. completion 2025-12-30 Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT06090786
Kinetics and Impact on Survival of MRD in AML Patients Receiving Azacitidine and Venetoclax
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 225 participants Est. completion 2027-07Other conditions: AML, Adult, Minimal Residual DiseaseView official trial listing → -
Status unknown NCT NCT06105658
Safety and Efficacy of Unrelated Umbilical Cord Blood Microtransplantation in Patients With AML
Not yet reported Anhui Provincial Hospital 20 participants Est. completion 2026-02-01 1 site Stand-aloneOther conditions: Acute Myelocytic LeukemiaView official trial listing → -
Status unknown NCT NCT06109064
Safety and Efficacy of Unrelated Umbilical Cord Blood Microtransplantation in Patients With Higher-risk MDS
Not yet reported Anhui Provincial Hospital 14 participants Est. completion 2026-02-01 1 site Stand-aloneOther conditions: Myelodysplastic SyndromesView official trial listing → -
Active, not recruiting NCT NCT06125795
A Study to Assess Change in Functioning and Health Related Quality of Life in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Treatments in Routine Clinical Practice in Spain
AbbVie 146 participants Est. completion 2026-07 25 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT06150040
Acute Myeloid Leukemia Treated With With NETrin Abs in Combination With [AZACITIDINE + VENETOCLAX]
Not yet reported, Not yet reported Centre Leon Berard 1 participants Est. completion 2025-02-18 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia RefractoryView official trial listing → -
Terminated NCT NCT06158100
Venetoclax in Combination With Azacitidine (VEN/AZA) Followed by Donor Lymphocyte Infusion (DLI) for Patients With Very High-Risk Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)
Not yet reported Antonio M Jimenez Jimenez 2 participants Est. completion 2026-06-02 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT06162325
Venetoclax in Combination With Standard Induction and Consolidation Chemotherapy in Newly Diagnosed Young AML Patients
Peking Union Medical College Hospital 45 participants Est. completion 2025-12-31 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT06200220
Patients Treated in Real Life With VEnetoclax for WAldenström Macroglobulinemia
Poitiers University Hospital 45 participants Est. completion 2025-12-01 1 siteOther conditions: Waldenstrom's Macroglobulinaemia RefractoryView official trial listing → -
Withdrawn NCT NCT06210750
Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)
Not yet reported National Cancer Institute (NCI) Est. completion 2026-09-22 Stand-aloneOther conditions: T Acute Lymphoblastic Leukemia, T Lymphoblastic LymphomaView official trial listing → -
Active, not recruiting NCT NCT06232655
Cladribine Venetoclax in Monocytic AML
Not yet reported University of Colorado, Denver 10 participants Est. completion 2027-10 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT06247540
Venetoclax, Rituximab and Nivolumab in Combination for the Treatment of Richter's Transformation Arising From Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Not yet reported Northwestern University Est. completion 2031-12-29 1 site Stand-aloneOther conditions: Recurrent Transformed Chronic Lymphocytic Leukemia, Refractory Transformed Chronic Lymphocytic Leukemia, Richter Syndrome, Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma, Transformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT06252584
Multi-peptide Vaccination Adjuvanted With XS15 in Acute Myeloid Leukemia Patients
Not yet reported University Hospital Tuebingen 20 participants Est. completion 2026-11-02 Stand-aloneOther conditions: Acute Myeloid Leukemia, AdultView official trial listing → -
Status unknown NCT NCT06263387
Results From a French Temporary Utilization Authorization of First-line Acute Myeloid Leukemia (AML) Patients Ineligible for Intensive Chemotherapy (IC), Treated With Venetoclax Azacitidine
French Innovative Leukemia Organisation 230 participants Est. completion 2025-03-30 42 sitesOther conditions: AML, AdultView official trial listing → -
Status unknown NCT NCT06285136
Safety and Efficacy of Venetoclax Combination With Decitabine(DEC3-VEN) in the Treatment of AML in the Adult
Not yet reported, Not yet reported The Second Affiliated Hospital of Kunming Medical University 40 participants Est. completion 2026-03-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, AdultView official trial listing → -
Not yet recruiting NCT NCT06295029
Personalized Medication Software for BCL-2 Inhibitor in AML Patients Using Machine Learning and Genomics
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 200 participants Est. completion 2027-12-31Other conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT06311227
Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia
Not yet reported National Cancer Institute (NCI) 20 participants Est. completion 2027-05-20 21 sites Stand-aloneOther conditions: Recurrent Hairy Cell Leukemia, Recurrent Hairy Cell Leukemia VariantView official trial listing → -
Not yet recruiting NCT NCT06324994
Linperlisib Plus Obinutuzumab and Venetoclax for Relapsed and Refractory Blastoid Variant of Mantle Cell Lymphoma.
Not yet reported Dalian Medical University 10 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Withdrawn NCT NCT06337331
Adding Venetoclax to the High-dose Chemotherapy Regimen Prior to Mismatche Allogeneic Stem Cell Transplant
Not yet reported Northside Hospital, Inc. Est. completion 2027-08-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Withdrawn NCT NCT06362031
A Study to Explore Treatment Patterns, Treatment Outcomes, Healthcare Resource Utilization in Adult Participants With Acute Myeloid Leukemia (AML) Receiving Venetoclax Through Chart Review
AbbVie Est. completion 2024-04-30Other conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT06362044
A Study to Assess Frequency of Undetectable Minimal Residual Disease (uMRD) in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Venetoclax Tablets ± Intravenously (IV) Infused Rituximab in Routine Clinical Practice in Japan
AbbVie 89 participants Est. completion 2024-12-31 1 siteOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT06382168
DFP-10917 in Combination With Venetoclax in Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported Delta-Fly Pharma, Inc. 39 participants Est. completion 2026-06-30 4 sites Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Active, not recruiting NCT NCT06384261
A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy
Not yet reported OncoVerity, Inc. 140 participants Est. completion 2027-06 38 sites Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Not yet recruiting NCT NCT06387420
A Study of AK117 in Combination With Azactidine Plus Venetoclax in Patients With Acute Myeloid Leukemia
Not yet reported, Not yet reported Akeso 180 participants Est. completion 2027-04 1 site Stand-aloneOther conditions: ACUTE MYELOID LEUKEMIA; AMLView official trial listing → -
Terminated NCT NCT06419634
Study of BMS-986497 (ORM-6151) as a Monotherapy, in Double and Triple Combination With Azacitidine and Venetoclax in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported Bristol-Myers Squibb 34 participants Est. completion 2026-08-28 10 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT06429098
Study of A Venetoclax-based, Anthracycline-free Regimen in Newly Diagnosed CBFβ::MYH11(+) AML
Not yet reported The First Affiliated Hospital of Soochow University 40 participants Est. completion 2027-12-31 2 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT06429670
Real World Use of Azacitidine and Venetoclax in Acute Myeloid Leukemia in Frontline and Relapse/Refractory
Hospices Civils de Lyon 500 participants Est. completion 2023-09-01 12 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT06434662
Mitoxantrone Hydrochloride Liposome Injection, Cytarabine Combined With Venetoclax in the Treatment of R/R AML
Not yet reported First Affiliated Hospital of Zhejiang University 34 participants Est. completion 2026-06 1 site Stand-aloneOther conditions: Relapsed/Refractory Acute Myeloid Leukaemia, Myeloid MalignancyView official trial listing → -
Active, not recruiting NCT NCT06445907
Phase I Study of Q702 With Azacitidine and Venetoclax for Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 17 participants Est. completion 2028-07-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT06449482
Selinexor、Venetoclax and Azactidine in the Treatment of ND AML Patients Who Are Not Eligible for Intense Chemotherapy
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 6 participants Est. completion 2025-03-30 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, AdultView official trial listing → -
Status unknown NCT NCT06450145
Evaluate the Efficacy and Safety of Interferon-α Combined With ATO in the Treatment of Arsenic-resistant APL
Not yet reported Zhejiang Provincial People's Hospital 15 participants Est. completion 2025-12-31 2 sites Stand-aloneOther conditions: TumourView official trial listing → -
Suspended NCT NCT06454409
Regorafenib in Combination With Venetoclax and Azacitidine for the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported City of Hope Medical Center 20 participants Est. completion 2030-09-06 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome/Acute Myeloid Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT06456463
A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy
Not yet reported Stemline Therapeutics, Inc. 85 participants Est. completion 2030-02-11 32 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT06470841
CHG Combined With Venetoclax and Azacytidine in Newly Diagnosed AML
Not yet reported Navy General Hospital, Beijing 85 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT06508489
A Study to Investigate Natural Killer Cell Engager (SAR443579) With Different Agents in Participants With Hematological Malignancies
Not yet reported, Not yet reported Sanofi 7 participants Est. completion 2025-08-08 7 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Suspended NCT NCT06514261
Testing the Combination of an Anti-Cancer Drug, Iadademstat, With Other Anti-Cancer Drugs (Venetoclax and Azacitidine) for Treating AML
Not yet reported National Cancer Institute (NCI) 45 participants Est. completion 2027-09-16 4 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT06516978
A Study Comparing the Efficacy and Safety of Pola-RCHP-X Versus RCHOP-X and Pola-RCHP in Previously Untreated Patients With DLBCL
Not yet reported The First Affiliated Hospital with Nanjing Medical University 528 participants Est. completion 2029-04-01 Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT06522386
GATE1: A Multicenter Phase II Study of Pirtobrutinib, Rituximab and Venetoclax Combination Therapy for Patients With Previously Untreated Mantle Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 50 participants Est. completion 2029-02-28 2 sites Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT06524375
A Study to Evaluate the Effect of Venetoclax on Participants Receiving a Covalent Bruton's Tyrosine Kinase Inhibitor (cBTKi) for First-line Chronic Lymphocytic Leukemia (1L CLL) to Achieve Deep Durable Remissions to Allow Off-treatment Period
Not yet reported Genentech, Inc. 118 participants Est. completion 2030-01-31 20 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT06532058
Phase IIa Study to Assess Safety and Efficacy in the Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Changzhou Qianhong Bio-pharma Co., Ltd. 53 participants Est. completion 2025-05-10 10 sites Stand-aloneOther conditions: Relapsed/Refractory Acute Myeloid Leukemia (R/R-AML)View official trial listing → -
Enrolling by invitation NCT NCT06544109
Venetoclax for Prevention of Differentiation Syndrom in Acute Promyelocytic Leukemia Patients
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 98 participants Est. completion 2028-08-01 1 site Stand-aloneOther conditions: Acute Promyelocytic LeukemiaView official trial listing → -
Terminated NCT NCT06563804
A Study to Evaluate S227928 as a Single Agent and in Combination With Venetoclax in Patients With R/R AML, MDS/AML, or CMML
Not yet reported, Not yet reported Servier Bio-Innovation LLC 13 participants Est. completion 2025-10-09 16 sites Stand-aloneOther conditions: Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)/AML, Chronic Myelomonocytic Leukemia (CMML)View official trial listing → -
Status unknown NCT NCT06578546
Chemotherapy-free Regimen of Venetoclax, Azacitidine Plus Orebatinib (VAO Regimen) for Newly Diagnosed ph+ALL
Not yet reported The First Affiliated Hospital of Soochow University 30 participants Est. completion 2026-02-01 1 site Stand-aloneOther conditions: Ph-Positive Acute Lymphoblastic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT06598384
VA as Maintenance Therapy Post Allo-HSCT in MDS and AML
Not yet reported Navy General Hospital, Beijing 40 participants Est. completion 2030-09 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT06629818
Daratumumab Combined With Venetoclax and Dexamethasone for Newly Diagnosed Light-Chain Amyloidosis With Translocation (11;14)
Not yet reported Peking Union Medical College Hospital 36 participants Est. completion 2027-03-14 1 site Stand-aloneOther conditions: Light Chain (AL) AmyloidosisView official trial listing → -
Active, not recruiting NCT NCT06651229
A Study of JNJ-90189892 for Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Neoplasms
Not yet reported Janssen Research & Development, LLC 85 participants Est. completion 2028-02-09 9 sites Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Myelodysplastic NeoplasmsView official trial listing → -
Not yet recruiting NCT NCT06652685
Molecular Subtype Combined with Early Minimal Residual Disease to Optimize the Treatment of Newly Diagnosed Acute Myeloid Leukemia
Not yet reported Ruijin Hospital 218 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Active, not recruiting NCT NCT06668558
Venetoclax + Azacitidine in Patients With Acute Myeloid Leukemia
Not yet reported Grupo Cooperativo de Estudio y Tratamiento de las Leucemias Agudas y Mielodisplasias 28 participants Est. completion 2028-07 14 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Enrolling by invitation NCT NCT06697327
Daunorubicin + Cytarabine + Venetoclax in de Novo AML
Not yet reported Anhui Medical University 94 participants Est. completion 2026-08-01 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT06742086
A Study to Evaluate the Bioavailability and Food Effects of Oral Venetoclax New Tablet Formulation 2.0 in Healthy Adult Female Participants
Not yet reported AbbVie 72 participants Est. completion 2025-10-08 2 sites Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Active, not recruiting NCT NCT06744556
HAV Versus DAV/IAV Induction Regimen in Elderly Patients With AML
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 41 participants Est. completion 2028-06-01 1 site Stand-aloneOther conditions: AMLView official trial listing → -
Not yet recruiting NCT NCT06763666
CLAG+VEN vs CLAG in the Treatment of Relapsed/Refractory AML
Not yet reported Nanfang Hospital, Southern Medical University 172 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: Relapsed/Refractory AMLView official trial listing → -
Not yet recruiting NCT NCT06765928
Selinexor Combined With Venetoclax Maintenance Therapy After Allo-HSCT
Not yet reported Ruijin Hospital 73 participants Est. completion 2028-01-01 1 site Stand-aloneOther conditions: MDS, AML, AdultView official trial listing → -
Active, not recruiting NCT NCT06768476
CART123 + Ruxolitinib in Relapsed/Refractory AML
Not yet reported University of Pennsylvania 12 participants Est. completion 2045-03 1 site Stand-aloneOther conditions: Relapsed AML, Refractory AMLView official trial listing → -
Withdrawn NCT NCT06770257
Daunorubicin, Cytarabine Liposomes Plus Venetoclax vs Azacitidine Plus Venetoclax in AML Patients Unfit for Intensive Chemotherapy
Not yet reported Institute of Hematology & Blood Diseases Hospital, China Est. completion 2027-06-10 Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Suspended NCT NCT06802523
Testing the Combination of Targeted Radiotherapy With Anti-Cancer Drugs, Venetoclax and ASTX-727, to Improve Outcomes for Adults With Newly Diagnosed Acute Myeloid Leukemia
Not yet reported National Cancer Institute (NCI) 53 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT06841952
Study of Tretinoin Capsules in Combination With Azacitidine and Venetoclax in Treatment Naïve Participants With Acute Myeloid Leukemia
Not yet reported The First Affiliated Hospital of Soochow University 158 participants Est. completion 2030-12-15 1 site Stand-aloneOther conditions: AML, AdultView official trial listing → -
Withdrawn NCT NCT06903702
A Study of Azacitidine and Venetoclax Versus a Stem Cell Transplant in People 65 Years and Older With Acute Myeloid Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2027-06 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT06954987
Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
Not yet reported National Cancer Institute (NCI) 244 participants Est. completion 2028-05-15 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT06991920
Immune-targeted Combination With Chemotherapy for Acute Leukemia of Ambiguous Lineage
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 50 participants Est. completion 2032-04-01 Stand-aloneOther conditions: Adult ALL, MPALView official trial listing → -
Completed NCT NCT06993883
Use of Venetoclax , AML , Sohag , Egypt
Sohag University 43 participants Est. completion 2025-04-30 1 siteOther conditions: AML (Acute Myelogenous Leukemia)View official trial listing → -
Enrolling by invitation NCT NCT07014462
A Phase 1B Investigator Initiated Study of Safety and Tolerability of Dexamethasone (D) in Combination With Venetoclax-based Low-Intensity Therapy (LIT) in Treatment-Naïve Acute Myeloid Leukemia (AML): DLIT-AML
Not yet reported University of Vermont 20 participants Est. completion 2029-06 1 site Stand-aloneOther conditions: AML - Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07026942
Phase I/II Clinical Trial of Universal Donor CD33 CAR Natural Killer Cells for AML
Not yet reported, Not yet reported Nationwide Children's Hospital 42 participants Est. completion 2038-07-01 1 site Stand-aloneOther conditions: Relapsed/Refractory AMLView official trial listing → -
Not yet recruiting NCT NCT07052422
VEN+DAC+Bu2Flu4 vs Bu2Flu5 Conditioning Regimen for Elderly Myeloid Malignancies Undergoing Allo-HSCT
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 160 participants Est. completion 2029-12-31 Stand-aloneOther conditions: Older Patients, Myeloid Malignancies, Conditioning, Hematopoietic Stem Cell Transplantation (HSCT)View official trial listing → -
Not yet recruiting NCT NCT07082452
A Multicenter Trial Evaluating Efficacy and Safety of A Reduced Venetoclax Exposure To Seven Days Versus Standard Continuous Venetoclax Exposure Combined With Azacitidine in Treatment Naïve Subjects With Acute Myeloid Leukemia Who Are Ineligible for Intensive Induction
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 262 participants Est. completion 2031-03 1 site Stand-aloneOther conditions: Leukemia, B-Cell, Chronic, LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07091006
Efficacy and Safety of VAH as a Bridging Regimen to Allo-HCT in Relapsed/Refractory AML
Not yet reported Ruijin Hospital 44 participants Est. completion 2028-05-01 1 site Stand-aloneOther conditions: Relapse LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07153497
Testing the Use of an IDH1 Inhibitor, Olutasidenib, in Acute Myeloid Leukemia Added to ASTX727 and Venetoclax; in High-Risk MDS Added to ASTX727; and Alone in Low Risk MDS (A MyeloMATCH Treatment Substudy)
Not yet reported National Cancer Institute (NCI) 132 participants Est. completion 2030-04-26 Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT07163793
Pilot Study of Reduced Venetoclax Exposure
Not yet reported Northwell Health 41 participants Est. completion 2028-02 1 siteOther conditions: Acute Myeloid Leukemia in RemissionView official trial listing → -
Not yet recruiting NCT NCT07175415
HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Not yet reported, Not yet reported Princess Maxima Center for Pediatric Oncology 42 participants Est. completion 2032-10-01 Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) RefractoryView official trial listing → -
Active, not recruiting NCT NCT07187505
Venetoclax Combined With ATRA and ATO in Hyperleukocytic Acute Promyelocytic Leukemia
Not yet reported Anhui Medical University 28 participants Est. completion 2027-07-01 1 site Stand-aloneOther conditions: Acute Promyelocytic Leukemia (APL)View official trial listing → -
Active, not recruiting NCT NCT07199855
Blinatumomab Combined With Venetoclax as Maintenance Therapy After Allo-HSCT in High-risk Ph Negative Acute B-cell Lymphoblastic Leukemia
Not yet reported Zhejiang University 24 participants Est. completion 2029-07-01 1 site Stand-aloneOther conditions: B-Cell Acute Lymphoblastic Leukemia, AdultView official trial listing → -
Not yet recruiting NCT NCT07214064
Venetoclax- Augmented Treosulfan-Based Reduced Intensity Conditioning Before Allogeneic Stem Cell Transplantation
Not yet reported University Hospital Tuebingen 27 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: AML (Acute Myeloid Leukemia), MDS/AML, MDS (Myelodysplastic Syndrome)View official trial listing → -
Completed NCT NCT07236931
Clinical Study of Selinexor-Based Chemotherapy With Minimal or No Cytotoxic Agents in Treatment-Naïve AML Patients Unsuitable for Intensive Therapy: Focusing on Rapid Reduction of Blast Cells
Not yet reported Donghua Zhang 103 participants Est. completion 2026-07-15 1 site Stand-aloneOther conditions: AML (Acute Myeloid Leukemia)View official trial listing → -
Completed NCT NCT07254611
Combination of HMA and Venetoclax With Posaconazole in Patients With Acute Myeloid Leukemia: A Study of Plasma Concentrations
Fondazione IRCCS Policlinico San Matteo di Pavia 15 participants Est. completion 2023-02-15 1 siteOther conditions: AML (Acute Myelogenous LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07264010
Sorafenib Combined With Venetoclax as Pre-emptive Therapy Strategy for MRD+ AML: a Prospective, Single-arm, Multicenter Clinical Study
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 87 participants Est. completion 2028-12-30 Stand-aloneOther conditions: Acute Myeloid Leukaemia (AML), Measurable Residual Disease (MRD)View official trial listing → -
Active, not recruiting NCT NCT07318662
Efficacy and Safety of HMAs Combined With Venetoclax Versus HMAs Alone in ND Int-and H-risk MDS or CMML
Guangdong Provincial People's Hospital 224 participants Est. completion 2027-03-30 1 siteOther conditions: MDS, CMMLView official trial listing → -
Not yet recruiting NCT NCT07319793
Pre-DLI or Pro-DLI in Relapsed/Refractory Myeloid Neoplasms After HSCT
Not yet reported Peking University People's Hospital 200 participants Est. completion 2028-06-30Other conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes (MDS)View official trial listing → -
Active, not recruiting NCT NCT07387471
Study to Assess Change in Disease Activity of Oral Venetoclax in Adult Participants With Recurring Relapsed or Refractory (R/R) Waldenström Macroglobulinemia (WM)/Lymphoplasmacytic Lymphoma (LPL)
Not yet reported AbbVie 14 participants Est. completion 2028-07 17 sites Stand-aloneOther conditions: Waldenstrom Macroglobulinemia, Lymphoplasmacytic LymphomaView official trial listing → -
Not yet recruiting NCT NCT07392814
Study With Tocilizumab in Combination With Venetoclax and Azacitidine Chemotherapy in Patients With Acute Myeloid Leukemia
Not yet reported Nantes University Hospital 12 participants Est. completion 2030-07-10 1 site Stand-aloneOther conditions: Leukemia Acute Myeloid - AMLView official trial listing → -
Not yet recruiting NCT NCT07407140
VAG Versus Standard Chemotherapy With FLT3 Inhibitor in Adult Patients With FLT3-Mutated AML
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 300 participants Est. completion 2030-12-31 Stand-aloneOther conditions: AML, AdultView official trial listing → -
Not yet recruiting NCT NCT07407660
Shortened Venetoclax Duration Based on Day 14 BM Blasts Versus Standard Therapy in Elderly or Frail Patients With AML Patients Treated With Azacitidine Plus Venetoclax
Not yet reported Peking University People's Hospital 250 participants Est. completion 2030-02-01 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07423104
A Study of Cladribine, Low Dose Cytarabine, and Venetoclax in Treatment of Relapsed/Refractory or Secondary Acute Myeloid Leukemia
Not yet reported University of Rochester 24 participants Est. completion 2030-02-01 Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07425808
FLT3-ITD Targeted Therapy in Fit AML Patients
Not yet reported, Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 230 participants Est. completion 2032-02-01 Stand-aloneOther conditions: AML (Acute Myeloid Leukemia)View official trial listing → -
Not yet recruiting NCT NCT07469046
VAH vs VA in Newly Diagnosed Elderly AML
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 308 participants Est. completion 2029-03-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Elderly Patients (60-75 Years)View official trial listing → -
Not yet recruiting NCT NCT07486479
Venetoclax, Azacitidine, and Mitoxantrone Hydrochloride Liposome Versus Idarubicin and Cytarabine in Newly Diagnosed AML
Not yet reported The First Affiliated Hospital of Soochow University 204 participants Est. completion 2027-12-31 21 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07486726
Aclarubicin Plus With Azacitidine and Venetoclax in the Treatment of Acute Myeloid Leukemia
Not yet reported, Not yet reported Shanghai Jiao Tong University School of Medicine 112 participants Est. completion 2028-10 4 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Relapse Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07505160
Efficacy and Safety of Lisafotoclax Plus Decitabine and Homoharringtonine in Venetoclax/Azacitidine Pretreated AML Patients
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 35 participants Est. completion 2029-03 1 siteOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07507825
Exploratory Study of Venetoclax, Homoharringtonine, Azacitidine Plus G-CSF for Newly Diagnosed AML (VHAG)
Not yet reported First People's Hospital of Hangzhou 61 participants Est. completion 2029-03-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07511062
Axatilimab Combined With Decitabine/Venetoclax for the Treatment of TP53-mutated AML
Not yet reported Northside Hospital, Inc. 32 participants Est. completion 2030-08-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, TP53 Gene MutationView official trial listing → -
Enrolling by invitation NCT NCT07517510
HVA in the Treatment of Mixed-Phenotype Acute Leukemia(MPAL).
Not yet reported Guangdong Second Provincial General Hospital 40 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Newly Diagnosed Mixed Phenotype Acute Leukemia (MPAL)View official trial listing → -
Not yet recruiting NCT NCT07521124
ABC Maintenance Therapy for AML
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 104 participants Est. completion 2029-06-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML) in RemissionView official trial listing → -
Not yet recruiting NCT NCT07522801
A Precision Medicine Trial for Patients With Relapsed or Refractory T Cell ALL
Not yet reported Philippe ROUSSELOT 93 participants Est. completion 2030-03-01 69 sites Stand-aloneOther conditions: LALView official trial listing → -
Enrolling by invitation NCT NCT07537257
VEN+IDAC vs IDAC in AML
Not yet reported, Not yet reported Guangdong Second Provincial General Hospital 232 participants Est. completion 2029-04-01 1 site Stand-aloneOther conditions: AML (Acute Myelogenous Leukemia)View official trial listing → -
Active, not recruiting NCT NCT07541755
PD-1 Inhibitors +Venetoclax+CAG Regimens in R/R T-ALL
Not yet reported Fujian Medical University Union Hospital 40 participants Est. completion 2029-01-31 1 site Stand-aloneOther conditions: Acute T Lymphoblastic Leukemia (T-ALL)View official trial listing → -
Not yet recruiting NCT NCT07572695
Salvage Haploidentical HSCT With DLI and Targeted Therapy for R/R AML
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 40 participants Est. completion 2028-12Other conditions: Acute Myeloid Leukemia, Relapsed/Refractory Acute Myeloid Leukemia, AML, Relapsed/RefractoryView official trial listing → -
Not yet recruiting NCT NCT07582159
Tafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Not yet reported City of Hope Medical Center 35 participants Est. completion 2029-04-14 2 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Small Lymphocytic LymphomaView official trial listing → -
Not yet recruiting NCT NCT07602322
LME-Guided Precision Combination Therapy in B-cell Lymphoma Patients After CD19 CAR-T Failure
Not yet reported Ruijin Hospital 60 participants Est. completion 2028-11-01 1 site Stand-aloneOther conditions: Large B-cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT07604233
Phase 1/2 FLAG-IDA, VEN and Asciminib in CML and Ph+ AML
Not yet reported, Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2033-06-03 1 site Stand-aloneOther conditions: Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07605949
Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML
Not yet reported UNC Lineberger Comprehensive Cancer Center 88 participants Est. completion 2028-07 1 site Stand-aloneOther conditions: Leukemia Acute MyeloidView official trial listing → -
Not yet recruiting NCT NCT07623187
A Study to Assess How Well the Study Medicine IPN60340 Works in Combination With Azacitidine and Venetoclax, Compared to Placebo in Combination With Azacitidine and Venetoclax, in Participants With Newly Diagnosed Acute Myeloid Leukemia Who Cannot Receive Intensive Chemotherapy
Not yet reported, Not yet reported Ipsen 540 participants Est. completion 2032-05-31 Stand-aloneOther conditions: Acute Myeloid Leukaemia (AML), Acute Myeloid LeukaemiaView official trial listing → -
Not yet recruiting NCT NCT07632170
The Efficacy and Safety of Selinisole Combined With Azacitidine and Venetoclax in the Treatment of Newly Diagnosed High-risk Myeloid Tumors With TP53 Mutations
Not yet reported Bing Han 30 participants Est. completion 2027-10-01 1 site Stand-aloneOther conditions: Myeloid TumorsView official trial listing → -
Not yet recruiting NCT NCT07635485
VA Induction and Bridging Transplantation for Hypoplastic/Secondary AML
Not yet reported The First Affiliated Hospital of Soochow University 50 participants Est. completion 2029-08-31 1 site Stand-aloneOther conditions: Hypoplastic Acute Myeloid Leukemia, Secondary AML (Adult)View official trial listing → -
Not yet recruiting NCT NCT07642453
VA-CAG Two-Week vs. Three-Week Regimen for Induction Remission in Newly Diagnosed Acute Myeloid Leukemia.
Not yet reported Hematology department of the 920th hospital 110 participants Est. completion 2028-06-01 Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07643103
Immuno-Targeted Therapy Plus Low-Dose Chemotherapy for Newly Diagnosed Adult Ph-Negative B-ALL: A Prospective Umbrella Trial
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 32 participants Est. completion 2030-05-31 Stand-aloneOther conditions: Ph- Acute Lymphoblastic Leukemia (Ph-ALL)View official trial listing → -
Not yet recruiting NCT NCT07643636
Chidamide, Venetoclax, Azacitidine, and Homoharringtonine for High-risk Fit AML
Not yet reported Dongguan People's Hospital 46 participants Est. completion 2029-06-01 Stand-aloneOther conditions: AML (Acute Myeloid Leukemia)View official trial listing → -
Not yet recruiting NCT NCT07664839
Study on the Efficacy and Safety of VA Regimen Compared to "3+7" Regimen in Newly Diagnosed AML With NPM1 or IDH1/IDH2 Mutations
Not yet reported Shen yang 148 participants Est. completion 2032-05-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, NPM1 Mutation, IDH1 Mutation, IDH2 MutationView official trial listing → -
Not yet recruiting NCT NCT07679334
Phase I Trial of Pacritinib in Combination With Venetoclax and Azacitidine for the Treatment of Accelerated and Blast Phase Myeloproliferative Neoplasms
Not yet reported Roswell Park Cancer Institute 20 participants Est. completion 2029-09-01 1 site Stand-aloneOther conditions: Myeloproliferative NeoplasmView official trial listing → -
Not yet recruiting NCT NCT07690891
Nemtabrutinib With Venetoclax and Obinutuzumab in Patients With Chronic Lymphocytic Leukemia
Not yet reported Medical College of Wisconsin 30 participants Est. completion 2031-09-01 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07711327
Atrial Fibrillation Among Patients With Hematologic Malignancies on Tyrosine Kinase Inhibitor Therapy
Tina Baykaner 500 participants Est. completion 2031-08 3 sitesOther conditions: Atrial Fibrillation (AF), Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia, Mantle Cell Lymphoma, Marginal Zone LymphomaView official trial listing → -
Not yet recruiting NCT NCT07722767
A Phase 1b Study of CLN-049 in Combination With Azacitidine and Venetoclax in AML Patients
Not yet reported Cullinan Therapeutics Inc. 90 participants Est. completion 2030-08-31 5 sites Stand-aloneOther conditions: AML (Acute Myeloid Leukemia)View official trial listing → -
Not yet recruiting NCT NCT07726576
Venetoclax in Association With 3+7 and Midostaurin in FLT3-mutated Acute Myeloid Leukemia
Not yet reported, Not yet reported University Hospital, Bordeaux 41 participants Est. completion 2031-12 3 sites Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Not yet recruiting NCT NCT07735117
Mitoxantrone Hydrochloride Liposome, Cytarabine, G-CSF Plus Venetoclax vs. Azacitidine Plus Venetoclax for MDS-IB2 and Secondary/Elderly AML
Not yet reported Ruijin Hospital 168 participants Est. completion 2029-07-31 Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)View official trial listing → -
Not yet recruiting NCT NCT07738887
Epcoritamab Plus Venetoclax Plus Ibrutinib in Patients With Chronic Lymphocytic Leukemia With TP53 Alterations
Not yet reported The Lymphoma Academic Research Organisation 44 participants Est. completion 2032-06-30 29 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Not yet recruiting NCT NCT07748455
HMA-Venetoclax Induction in Newly Diagnosed AML
Not yet reported Pakistan Blood and Marrow Transplant (PBMT) Group 60 participants Est. completion 2027-12-31 1 siteOther conditions: AML, AML (Acute Myeloid Leukemia)View official trial listing → -
Not yet recruiting NCT NCT07754799
A Randomized Trial of Venetoclax-Based Induction Intensity in Newly Diagnosed Acute Myeloid Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 320 participants Est. completion 2029-09-30 Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07755202
Gilteritinib-Azacitidine-Venetoclax Combination Therapy in Patients With Relapsed/Refractory Leukemia
Not yet reported Florian Kuchenbauer 20 participants Est. completion 2030-05-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, AML With FLT3 MutationView official trial listing → -
Not yet recruiting NCT NCT07762508
A Study of VABu Conditioning Regimen in Allo-HSCT for AML Patients
Not yet reported The First Affiliated Hospital of Soochow University 42 participants Est. completion 2029-07 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute(AML), Hematopoietic Stem Cell Transplantation (HSCT)View official trial listing → -
Not yet recruiting NCT NCT07766850
Addition of Hydroxyurea to Fludarabine, Cytarabine, Idarubicin and Venetoclax Salvage Therapy for Adults With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported Christer C Nilsson 26 participants Est. completion 2034-09 1 site Stand-aloneOther conditions: R/R AMLView official trial listing → -
Completed NCT NCT07773909
Venetoclax With Hypomethylating Agents in Newly Diagnosed AML Unfit for Intensive Chemotherapy
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 24 participants Est. completion 2023-03-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07777471
Improving Delivery of Aging-Related Supportive Care for Older Adults With Acute Myeloid Leukemia
Not yet reported University of Alabama at Birmingham 40 participants Est. completion 2028-09-30 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Enrolling by invitation NCT NCT07813390
Homoharringtonine, Lisaftoclax, and Azacitidine for AML After Venetoclax-Based Therapy Failure
Not yet reported Guangdong Second Provincial General Hospital 73 participants Est. completion 2028-08-31 1 siteOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07814339
Hydrochloroquinine & Decitabine With Venetoclax in AML
Not yet reported Rutgers, The State University of New Jersey 18 participants Est. completion 2028-06 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07828535
Liposomal Mitoxantrone Plus Azacitidine and Venetoclax in Newly Diagnosed Elderly or Unfit AML
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 30 participants Est. completion 2032-12-31 Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07840976
Immunotargeted Therapy Plus Low-Dose Chemotherapy in Newly Diagnosed Adult Ph+ B-ALL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 22 participants Est. completion 2030-05-31 1 site Stand-aloneOther conditions: Ph+ Acute Lymphoblastic Leukemia (Ph+ALL)View official trial listing → -
Not yet recruiting NCT NCT07847957
Roginolisib Plus Obinutuzumab + Venetoclax in R/R CLL
Not yet reported, Not yet reported Dana-Farber Cancer Institute 40 participants Est. completion 2027-04-01 2 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia (CLL), Refractory Chronic Lymphocytic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07851012
Cardiotoxicity in Newly Diagnosed Acute Myeloid Leukemia Patients
Assiut University 146 participants Est. completion 2028-10-14Other conditions: Newly Diagnosed Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07862517
Testing the Investigational Medication Combination of Azacitidine, Venetoclax, and Quizartinib Compared to the Usual Treatment of Cytarabine, Daunorubicin, and Quizartinib for Patients With FLT3-ITD Mutant Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
Not yet reported National Cancer Institute (NCI) 122 participants Est. completion 2027-12-31 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07867626
Phase II De-Escalation Study of Metronomic Decitabine/Cedazuridine Plus Venetoclax in AML
Not yet reported Rutgers, The State University of New Jersey 41 participants Est. completion 2029-12 1 site Stand-aloneOther conditions: Acute Myeloid Leukaemia (AML)View official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Venetoclax, Venclexta, Venetoclax Oral Tablet, 200 mg, Venetoclax Oral Tablet, 400 mg
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
