About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Velpatasvir
- Company
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 6 recruiting
Efficacy results: Not yet reported
6 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 29, 2026
Find a Clinical Trial Near Me
See recruiting studies for Velpatasvir and check eligibility with the study team.
Trial details
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Recruiting NCT NCT03383419
Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients
Not yet reported Baylor Research Institute 15 participants Est. completion 2026-12-30 3 sites Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT05653232
Prophylaxis With Direct-acting Antivirals for Kidney Transplantation From HCV-Infected Donors to Uninfected Recipients
Not yet reported Johns Hopkins University 120 participants Est. completion 2028-03 9 sites Stand-aloneOther conditions: HCVView official trial listing → -
Recruiting NCT NCT06159504
Simplifying Hepatitis C Pathways for People Who Inject Drugs in Armenia, Georgia, and Tanzania
Not yet reported Médecins du Monde 3040 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Hepatitis C, RDTView official trial listing → -
Recruiting NCT NCT06180590
The Efficacy of Vosevi in Treating DAA-experienced Patients
The Third Affiliated Hospital of Guangzhou Medical University 200 participants Est. completion 2027-02-28 1 siteOther conditions: Chronic Hepatitis C, Medication ReactionView official trial listing → -
Recruiting NCT NCT06306300
Safety and Efficacy of Decentralized HCV Treatment vs Standard-of-Care in Rio de Janeiro (Brazil)
Not yet reported Oswaldo Cruz Foundation 30000 participants Est. completion 2026-12-31 2 sitesOther conditions: Hepatitis CView official trial listing → -
Recruiting NCT NCT06953479
Implementing Low-Barrier HCV Treatment in a Jail Setting
Not yet reported Lifespan 40 participants Est. completion 2027-08 1 site Stand-aloneOther conditions: HEPATITIS C (HCV), Incarceration, Injection Drug Use, Implementation ScienceView official trial listing → -
Completed NCT NCT01457755
Gilead Sustained Virologic Response (SVR) Registry
Gilead Sciences 6625 participants Est. completion 2018-01-08 325 sitesOther conditions: Hepatitis C, ChronicView official trial listing → -
Completed NCT NCT01457768
A Gilead Sequence Registry of Subjects Who Did Not Achieve Sustained Virologic Response
Gilead Sciences 570 participants Est. completion 2018-04-09 323 sitesOther conditions: Hepatitis C, ChronicView official trial listing → -
Completed NCT NCT01740791
Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Velpatasvir in Participants With Chronic HCV Infection
Not yet reported Gilead Sciences 103 participants Est. completion 2014-01-24 10 sites Stand-aloneOther conditions: Chronic Hepatitis C VirusView official trial listing → -
Completed NCT NCT01817985
A Phase 1 Study to Evaluate the Pharmacokinetics of GS-5816 in Subjects With Normal Hepatic Function and Moderate or Severe Hepatic Impairment
Not yet reported Gilead Sciences 33 participants Est. completion 2013-08 6 sitesOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT01826981
Efficacy and Safety of Sofosbuvir Containing Regimens for the Treatment of Chronic HCV Infection in Participants With Chronic Genotype 1, 2, 3, or 6 HCV Infection
Not yet reported Gilead Sciences 359 participants Est. completion 2015-05 2 sites Stand-aloneOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT01858766
Safety and Efficacy of Sofosbuvir + Velpatasvir With or Without Ribavirin in Treatment-Naive Adults With Chronic HCV Infection
Not yet reported Gilead Sciences 379 participants Est. completion 2014-08 51 sitesOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT01909804
Safety and Efficacy of Sofosbuvir Plus Velpatasvir With or Without Ribavirin in Treatment-experienced Subjects With Chronic HCV Infection
Not yet reported Gilead Sciences 323 participants Est. completion 2014-08 49 sitesOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT02002767
Study to Evaluate the Pharmacokinetics of Velpatasvir in Participants With Normal Renal Function and Severe Renal Impairment
Not yet reported Gilead Sciences 19 participants Est. completion 2014-06-09 5 sites Stand-aloneOther conditions: Hepatitis C VirusView official trial listing → -
Status unknown NCT NCT02057003
Real-life Security and Efficacy of DAA-based Therapy in HCV/HIV-Coinfected Patients
Valme University Hospital 1000 participants Est. completion 2020-12 1 siteOther conditions: Hepatitis C, Chronic, Human Immunodeficiency VirusView official trial listing → -
Completed NCT NCT02064049
Surveillance and Treatment of Prisoners With Hepatitis C
Not yet reported Kirby Institute 3692 participants Est. completion 2019-11 4 sites Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT02185794
Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Voxilaprevir in Adults With Chronic Hepatitis C Virus Infection
Not yet reported Gilead Sciences 101 participants Est. completion 2015-09-28 11 sites Stand-aloneOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02201901
Sofosbuvir/Velpatasvir Fixed-Dose Combination in Adults With Chronic HCV Infection and Child-Pugh Class B Cirrhosis
Not yet reported Gilead Sciences 268 participants Est. completion 2015-11 50 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02201940
Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Adults With Chronic HCV Infection
Not yet reported Gilead Sciences 741 participants Est. completion 2015-09 80 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02201953
Comparison of Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks With Sofosbuvir and Ribavirin for 24 Weeks in Adults With Chronic Genotype 3 HCV Infection
Not yet reported Gilead Sciences 558 participants Est. completion 2015-12 76 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02202980
Efficacy and Safety of Oral Regimens for the Treatment of Chronic HCV Infection
Not yet reported Gilead Sciences 273 participants Est. completion 2016-05-09 2 sites Stand-aloneOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT02220998
Comparison of Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks With Sofosbuvir and Ribavirin for 12 Weeks in Adults With Chronic Genotype 2 HCV Infection
Not yet reported Gilead Sciences 269 participants Est. completion 2015-09 51 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Terminated NCT NCT02292706
A Registry for Participants With Cirrhosis Who Achieve a Sustained Virologic Response Following Treatment With a Sofosbuvir-Based Regimen Without Interferon for Chronic Hepatitis C Infection
Gilead Sciences 1609 participants Est. completion 2021-12-31 138 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02300103
Efficacy And Safety Of Sofosbuvir/Velpatasvir Fixed Dose Combination With Ribavirin in Chronic HCV Infected Adults Who Participated in a Prior Gilead Sponsored HCV Treatment Study
Not yet reported Gilead Sciences 69 participants Est. completion 2016-09-15 30 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02333292
Efficacy and Safety of Therapy Against HCV Based on Direct-acting Antivirals in Real-life Conditions
Valme University Hospital 1128 participants Est. completion 2017-06-30 1 siteOther conditions: Chronic Hepatitis C InfectionView official trial listing → -
Completed NCT NCT02336139
A Phase II Trial of Sofosbuvir (SOF) and GS-5816 for People With Chronic Hepatitis C Virus Infection and Recent Injection Drug Use
Not yet reported Kirby Institute 103 participants Est. completion 2018-11-28 1 siteOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT02346721
Sofosbuvir/Velpatasvir Fixed-Dose Combination in Adults With Chronic HCV Infection
Not yet reported Gilead Sciences 111 participants Est. completion 2016-06-15 61 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02378935
Safety and Efficacy of Voxilaprevir Plus Sofosbuvir/Velpatasvir Fixed Dose Combination in Adults With Chronic Genotype 1 HCV Infection
Not yet reported Gilead Sciences 205 participants Est. completion 2016-04-12 34 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02378961
Safety and Efficacy of Voxilaprevir Plus Sofosbuvir/Velpatasvir Fixed Dose Combination in Adults With Chronic Non-Genotype 1 HCV Infection
Not yet reported Gilead Sciences 128 participants Est. completion 2016-01-26 34 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02468648
Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected With Different Hepatitis C Virus Genotypes During Therapy With Sofosbuvir and GS-5816
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 72 participants Est. completion 2018-09-14 1 siteOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT02480712
Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Adults With Chronic Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV)-1 Coinfection
Not yet reported Gilead Sciences 107 participants Est. completion 2016-06-22 15 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Terminated NCT NCT02510300
A Registry for Adolescent and Pediatric Participants Who Received a Gilead Hepatitis C Virus Direct Acting Antiviral (DAA) in Gilead-Sponsored Chronic Hepatitis C Infection Trials
Gilead Sciences 461 participants Est. completion 2023-01-06 51 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02533427
Study to Evaluate Effect of Sofosbuvir/Velpatasvir/GS-9857 Fixed-Dose Combination on the Pharmacokinetics of a Representative Hormonal Contraceptive Medication, Norgestimate/Ethinyl Estradiol
Not yet reported Gilead Sciences 15 participants Est. completion 2016-03-18 1 siteOther conditions: HCV InfectionView official trial listing → -
Completed NCT NCT02536313
Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir Fixed-Dose Combination With or Without Ribavirin in Participants With Chronic Genotype 1 HCV Infection Previously Treated With a Direct Acting Antiviral Regimen
Not yet reported Gilead Sciences 49 participants Est. completion 2016-06-28 1 siteOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02607735
Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir in Adults With Chronic HCV Infection Who Have Previously Received Treatment With Direct-Acting Antiviral Therapy
Not yet reported Gilead Sciences 416 participants Est. completion 2017-06-21 86 sitesOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT02607800
Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Therapy
Not yet reported Gilead Sciences 943 participants Est. completion 2017-01-11 93 sitesOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT02625909
Randomised Study of Interferon-free Treatment for Recently Acquired Hepatitis C in PWID and People With HIV Coinfection.
Not yet reported Kirby Institute 222 participants Est. completion 2020-03-23 25 sitesOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT02639247
Safety and Efficacy of SOF/VEL/VOX FDC for 12 Weeks and SOF/VEL for 12 Weeks in DAA-Experienced Adults With Chronic HCV Infection Who Have Not Received an NS5A Inhibitor
Not yet reported Gilead Sciences 333 participants Est. completion 2017-01-18 78 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02639338
Safety and Efficacy of SOF/VEL/VOX FDC for 8 Weeks and SOF/VEL for 12 Weeks in Adults Chronic Genotype 3 HCV Infection and Cirrhosis
Not yet reported Gilead Sciences 220 participants Est. completion 2017-01-02 70 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Status unknown NCT NCT02657694
Reviewing DAA Efficacy Managing Patient Treatment In Online Neighbourhoods
FixHepC 10000 participants Est. completion 2018-06-30 1 siteOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT02671500
Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Participants With Chronic HCV
Not yet reported Gilead Sciences 375 participants Est. completion 2018-03-27 38 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02722837
Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination in Participants With Chronic Hepatitis C Virus Infection
Not yet reported Gilead Sciences 119 participants Est. completion 2017-09-13 15 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02728206
Sofosbuvir/Velpatasvir Fixed-Dose Combination in HCV-Infected Adults Who Are Undergoing Liver Transplantation
Not yet reported Gilead Sciences 9 participants Est. completion 2018-01-16 1 siteOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02745535
Safety, Tolerability and Efficacy of Sofosbuvir, Velpatasvir, and Voxilaprevir in Subjects With Previous DAA Experience
Not yet reported University of Maryland, Baltimore 77 participants Est. completion 2018-10-24 1 site Stand-aloneOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT02781558
Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination (FDC) and Sofosbuvir/Velpatasvir FDC and Ribavirin in Participants With Chronic Genotype 3 HCV Infection and Cirrhosis
Not yet reported Gilead Sciences 204 participants Est. completion 2017-10-27 28 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02781571
Sofosbuvir/Velpatasvir Fixed Dose Combination in Participants With Chronic Hepatitis C Virus Infection Who Have Received a Liver Transplant
Not yet reported Gilead Sciences 79 participants Est. completion 2017-07-28 15 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02822794
Sofosbuvir/Velpatasvir Fixed-Dose Combination and Ribavirin for 12 or 24 Weeks in Participants With Chronic Genotype 1 or 2 Hepatitis C Virus Infection Who Have Previously Failed a Direct-Acting Antiviral-Containing Regimen
Not yet reported Gilead Sciences 117 participants Est. completion 2017-08-25 18 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02825212
Efficacy of All-Oral Anti-Viral Therapy for Symptomatic Hepatitis C Virus Infection-Related Cryoglobulinemia
Not yet reported, Not yet reported Icahn School of Medicine at Mount Sinai 10 participants Est. completion 2019-07-19 1 site Stand-aloneOther conditions: Hepatitis C, CryoglobulinemiaView official trial listing → -
Completed NCT NCT02836925
Ledipasvir+Sofosbuvir and Sofosbuvir+Velpatasvir for Pts With Indolent Bcell Lymphoma Associated With HCV Infection
Not yet reported Fondazione Italiana Linfomi - ETS 40 participants Est. completion 2022-11 13 sites Stand-aloneOther conditions: Indolent B-cell Lymphoma, Hepatitis CView official trial listing → -
Completed NCT NCT02938013
deLIVER: Direct Acting Antiviral Effects on the Liver
Not yet reported Johns Hopkins University 15 participants Est. completion 2020-09-30 1 site Stand-aloneOther conditions: HCV Coinfection, Liver Disease, HIVView official trial listing → -
Completed NCT NCT02994056
Evaluate the Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination and Ribavirin for 12 Weeks in Participants With Chronic HCV Infection and Child-Pugh-Turcotte Class C Cirrhosis
Not yet reported Gilead Sciences 32 participants Est. completion 2018-12-12 12 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT02996682
Efficacy and Safety of Sofosbuvir/Velpatasvir ± Ribavirin for 12 Weeks in Adults With Chronic HCV Infection and Decompensated Cirrhosis
Not yet reported Gilead Sciences 102 participants Est. completion 2018-05-08 33 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Status unknown NCT NCT03018353
Curing HCV in Incarcerated Patients
Not yet reported San Francisco Department of Public Health 100 participants Est. completion 2018-06-04 1 siteOther conditions: Hepatitis C, ChronicView official trial listing → -
Completed NCT NCT03022981
Study to Investigate the Safety and Efficacy of Sofosbuvir/Velpatasvir in Adolescents and Children With Chronic HCV Infection
Not yet reported Gilead Sciences 216 participants Est. completion 2020-02-26 27 sites Stand-aloneOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT03032666
Sofosbuvir/Ledipasvir for Hepatitis C Genotype 1-6 in Patients With Transfusion-Dependent Thalassemia: An Open Label Trial
Not yet reported Ala'a Sharara 7 participants Est. completion 2018-08-06 1 site Stand-aloneOther conditions: Thalassemia, Hepatitis CView official trial listing → -
Completed NCT NCT03036852
Sofosbuvir/Velpatasvir in Adults With Chronic Hepatitis C Virus Infection Who Are on Dialysis for End Stage Renal Disease
Not yet reported Gilead Sciences 59 participants Est. completion 2018-11-07 22 sitesOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT03057847
Sofosbuvir/Velpatasvir in Postpartum Women With Opioid Use Disorder and Chronic Hepatitis C Infection
Not yet reported Elizabeth Krans, MD 32 participants Est. completion 2022-02-24 1 site Stand-aloneOther conditions: Hepatitis C, Chronic, Opioid-use DisorderView official trial listing → -
Completed NCT NCT03074331
Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Adults With Chronic Hepatitis C Virus (HCV) Infection
Not yet reported Gilead Sciences 130 participants Est. completion 2018-02-07 16 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Status unknown NCT NCT03086044
Transplanting Hepatitis C Positive Organs
Not yet reported Brigham and Women's Hospital 148 participants Est. completion 2023-12 1 site Stand-aloneOther conditions: Hepatitis C, Awaiting Organ TransplantView official trial listing → -
Active, not recruiting NCT NCT03112044
Lung Transplant HCV, Pilot Study
Not yet reported University Health Network, Toronto 26 participants Est. completion 2027-05-31 1 site Stand-aloneOther conditions: Lung Transplant Infection, Hepatitis CView official trial listing → -
Completed NCT NCT03118843
Safety And Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir Fixed-Dose Combination for 12 Weeks in Adults Who Participated in a Prior Gilead-Sponsored HCV Treatment Study
Not yet reported Gilead Sciences 31 participants Est. completion 2018-03-19 27 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Status unknown NCT NCT03164902
Digimeds to Optimize Adherence in Patients With Hepatitis C and Increased Risk for Nonadherence
Not yet reported Proteus Digital Health, Inc. 253 participants Est. completion 2019-04-30 16 sites Stand-aloneOther conditions: Hepatitis C, Chronic, Nonadherence, PatientView official trial listing → -
Terminated NCT NCT03207399
Lung Transplantation in Chronic HCV Infection With Post Transplant EPCLUSA Treatment
Not yet reported Duke University 1 participants Est. completion 2019-03-25 1 siteOther conditions: Hepatitis C, Chronic, Lung TransplantView official trial listing → -
Terminated NCT NCT03208127
DAA Treatment in Donor HCV-positive to Recipient HCV-negative Liver Transplant
Not yet reported Massachusetts General Hospital 33 participants Est. completion 2021-06-04 1 siteOther conditions: End Stage Liver Disease, Hepatitis CView official trial listing → -
Completed NCT NCT03222531
Expanding the Pool in Orthotopic Heart Transplantation
Not yet reported Mary E. Keebler, MD 20 participants Est. completion 2026-06-02 1 site Stand-aloneOther conditions: Hepatitis C, Heart Transplant, Cardiac TransplantView official trial listing → -
Completed NCT NCT03235154
A Pilot Study of Treating HCV at a Psychiatrist-staffed Outpatient Addiction Clinic
Not yet reported Community Research Initiative of New England 11 participants Est. completion 2019-09-26 1 siteOther conditions: Hepatitis C, Chronic, Hepatitis C, Opiate DependenceView official trial listing → -
Completed NCT NCT03249194
Hepatitis C Virus Donor Positive Kidney Transplantation for Hepatitis C Virus Negative Recipients
Not yet reported Virginia Commonwealth University 25 participants Est. completion 2020-03-15 1 site Stand-aloneOther conditions: Kidney Transplant, Hepatitis CView official trial listing → -
Completed NCT NCT03250910
Generic VEL/SOF With or Without RBV for HIV/HCV Coinfected Patients
Not yet reported National Taiwan University Hospital 228 participants Est. completion 2017-10-31 2 sites Stand-aloneOther conditions: Hepatitis C Virus Infection, Response to Therapy of, Human Immunodeficiency VirusView official trial listing → -
Withdrawn NCT NCT03313414
HCV Post-Exposure Prophylaxis for Health Care Workers
Not yet reported Massachusetts General Hospital Est. completion 2020-01-16 1 site Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT03377478
Expanding the Pool in Lung Transplantation
Not yet reported Pablo Sanchez 10 participants Est. completion 2022-04-01 1 site Stand-aloneOther conditions: Hepatitis C, Lung TransplantView official trial listing → -
Withdrawn NCT NCT03389061
Bioequivalence Study of Crushed Sofosbuvir/Velpatasvir Compared to the Whole Tablet
Not yet reported Radboud University Medical Center Est. completion 2019-03-22 3 sites Stand-aloneOther conditions: HCVView official trial listing → -
Completed NCT NCT03423641
An Observational Study of the Safety of Direct-acting Antivirals in Patients With Hepatitis C
Kaiser Permanente 33808 participants Est. completion 2017-12-31Other conditions: Hepatitis C, ChronicView official trial listing → -
Terminated NCT NCT03483987
Re-treatment of HCV Following DAA Failure
Not yet reported Sanjay Gandhi Postgraduate Institute of Medical Sciences 18 participants Est. completion 2022-04-30 2 sites Stand-aloneOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT03492112
A TEst and Treat Intervention aMong Current People Who Inject Drugs With HCV Attending Needle and Syringe PrOgrams
Not yet reported Kirby Institute 101 participants Est. completion 2021-11-30 1 site Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT03501550
Study of CDI-31244 in Combination With Sofosbuvir (SOF) and Velpatasvir (VEL)
Not yet reported Cocrystal Pharma, Inc. 12 participants Est. completion 2019-06-07 1 site Stand-aloneOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT03512210
Monitoring SOF/VEL in Treatment Naïve, HCV Participants With Active Infection
Not yet reported Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections 400 participants Est. completion 2021-02-28 38 sites Stand-aloneOther conditions: Hepatitis C, HIV-1-infection, Liver DiseasesView official trial listing → -
Completed NCT NCT03513393
Influence of Cola on the Absorption of the HCV Agent Velpatasvir in Combination With PPI Omeprazole.
Not yet reported Radboud University Medical Center 11 participants Est. completion 2018-12-01 1 site Stand-aloneOther conditions: Hepatitis C, Swallowing DisorderView official trial listing → -
Active, not recruiting NCT NCT03520660
People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 121 participants Est. completion 2032-12-31 1 site Stand-aloneCardiovascular disease Other conditions: Diabetes Mellitus, Hepatitis C, ChronicView official trial listing → -
Status unknown NCT NCT03549312
Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy
Not yet reported Saskatchewan Health Authority - Regina Area 25 participants Est. completion 2021-06-22 1 site Stand-aloneOther conditions: HIV-1-infection, Hepatitis C, Chronic, Methadone Dependence, Opioid Dependence, Bone Diseases, Metabolic, HIV/AIDS, Co-infection, Buprenorphine Dependence, HCV CoinfectionView official trial listing → -
Completed NCT NCT03570112
Transmission of Chronic Hepatitis C in Pregnancy
The Christ Hospital 40 participants Est. completion 2023-02-27 1 siteOther conditions: Hepatitis C, Pregnancy Complications, Vertical Disease TransmissionView official trial listing → -
Completed NCT NCT03579576
Simplified Antiviral Treatment Strategy for Hepatitis C in Myanmar
Right to Care 803 participants Est. completion 2019-06-30 3 sitesOther conditions: Hepatitis C, Hepatitis B, HIV InfectionsView official trial listing → -
Completed NCT NCT03619837
Prevention of De Novo HCV With Antiviral HCV Therapy Post-Liver and Post-Kidney Transplant
Not yet reported University of California, San Francisco 122 participants Est. completion 2020-08-13 6 sites Stand-aloneOther conditions: Hepatitis C, Transplantation Disease TransmissionView official trial listing → -
Terminated NCT NCT03625687
Pan-genotypic Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Lung Transplant
Not yet reported Massachusetts General Hospital 19 participants Est. completion 2022-04-04 1 site Stand-aloneOther conditions: Respiratory Failure, Hepatitis CView official trial listing → -
Completed NCT NCT03627546
HCV Seek, Test and Rapid Treatment for Young PWID
Not yet reported Weill Medical College of Cornell University 39 participants Est. completion 2021-06-30 1 site Stand-aloneOther conditions: Hepatitis C, Drug UseView official trial listing → -
Withdrawn NCT NCT03702218
Hepatitis C Positive Donor Into Hepatitis C Negative Recipients
Not yet reported University of Maryland, Baltimore Est. completion 2019-07-01 1 site Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT03724149
Transplanting Hepatitis C Lungs Into Negative Lung Recipients
Not yet reported, Not yet reported University of Pennsylvania 10 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: Lung DiseasesView official trial listing → -
Status unknown NCT NCT03776760
Strategies for Hepatitis C Testing and Treatment in Aboriginal Communities That Lead to Elimination
Kirby Institute 600 participants Est. completion 2022-08 4 sitesOther conditions: Hepatitis C, Hepatitis, Liver Diseases, Hepatitis, Viral, Human, RNA Virus Infections, Digestive System DiseasesView official trial listing → -
Completed NCT NCT03801707
Utilization of Hepatitis C Positive Kidneys in Negative Recipients
Not yet reported, Not yet reported Ohio State University 54 participants Est. completion 2021-04-30 1 site Stand-aloneOther conditions: Kidney Transplant, Hepatitis C, HCVView official trial listing → -
Active, not recruiting NCT NCT03809533
The Use of Hepatitis C Positive Kidneys in Hepatitis C Negative Kidney Transplant Recipients
Not yet reported Amit D Tevar, MD 30 participants Est. completion 2026-04-01 1 site Stand-aloneOther conditions: Kidney Transplantation, Hepatitis CView official trial listing → -
Completed NCT NCT03818308
Trial for the Treatment of Acute Hepatitis C for 8 Weeks With Sofosbuvir/Velpatasvir
Not yet reported Hannover Medical School 20 participants Est. completion 2021-06-08 14 sites Stand-aloneOther conditions: Hepatitis C, Acute Hepatitis CView official trial listing → -
Completed NCT NCT03819322
The Use of Hepatitis C Positive Livers in Hepatitis C Negative Liver Transplant Recipients
Not yet reported Fernanda P Silveira, MD, MS 5 participants Est. completion 2025-03-17 1 site Stand-aloneOther conditions: Liver Transplant, Hepatitis CView official trial listing → -
Terminated NCT NCT03820258
Study to Investigate Pharmacokinetics, Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX) Fixed Dose Combination (FDC) in Adolescents and Children With Chronic Hepatitis C Virus (HCV) Infection
Not yet reported Gilead Sciences 21 participants Est. completion 2020-02-19 10 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT03823911
Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes After Hepatitis C Eradication
Not yet reported University of Maryland, Baltimore 87 participants Est. completion 2022-12-31 2 sitesCardiovascular disease Other conditions: Hepatitis C, HivView official trial listing → -
Status unknown NCT NCT03887637
Real-world Effectiveness and Safety of Treatment With DAAs in Patients With CHC(Chronic Hepatitis C)
Third Affiliated Hospital, Sun Yat-Sen University 180 participants Est. completion 2019-09-30Other conditions: Chronic Hepatitis CView official trial listing → -
Status unknown NCT NCT03888729
Simplifying HCV Treatment in Rwanda for Elsewhere in the Developing World: Pangenotypic and Retreatment Study (SHARED3)
Not yet reported Partners in Health 100 participants Est. completion 2020-03 1 site Stand-aloneOther conditions: Hepatitis C, ChronicView official trial listing → -
Status unknown NCT NCT03891550
Micro-elimination of Hepatitis C Virus Infection in Uremics
Not yet reported Kaohsiung Medical University Chung-Ho Memorial Hospital 135 participants Est. completion 2024-04-15 1 site Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT03949764
The Kentucky Viral Hepatitis Treatment Study
Not yet reported Jennifer Havens 374 participants Est. completion 2025-06-30 1 site Stand-aloneOther conditions: Hepatitis C, Opioid-Related Disorders, Injection Drug UseView official trial listing → -
Active, not recruiting NCT NCT03981445
Integrated HIV Prevention and HCV Care for PWID
Not yet reported Columbia University 446 participants Est. completion 2026-09-30 3 sites Stand-aloneOther conditions: HIV Prevention, HCV, Opioid Use, Intravenous Drug UsageView official trial listing → -
Completed NCT NCT03987503
The No One Waits Study: Acceptability and Feasibility of Community-based Point-of-diagnosis HCV Treatment Study
Not yet reported University of California, San Francisco 87 participants Est. completion 2022-12-29 1 site Stand-aloneOther conditions: Hepatitis C, ChronicView official trial listing → -
Status unknown NCT NCT04039698
Monitoring of Hepatitis C Treatment Using Telemedicine - a Clinical Trial in Public Health System in Brazil
Not yet reported Hospital de Clinicas de Porto Alegre 144 participants Est. completion 2021-11 1 site Stand-aloneOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT04047680
eGFR Evolution in HCV Patients Receiving SOF-based or SOF-free DAAs
National Taiwan University Hospital 441 participants Est. completion 2019-06 2 sitesOther conditions: Hepatitis C, Renal Disease, Viral Hepatitis CView official trial listing → -
Completed NCT NCT04075916
A Trial of Transplanting Hepatitis C Kidneys Into Hepatitis C-Negative Kidney Recipients
Not yet reported University of Pennsylvania 201 participants Est. completion 2026-02-25 11 sites Stand-aloneOther conditions: End Stage Renal DiseaseView official trial listing → -
Completed NCT NCT04112303
Study to Investigate the Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed-Dose Combination for 12 Weeks in Adults With Chronic HCV Infection and Compensated Cirrhosis
Not yet reported Gilead Sciences 37 participants Est. completion 2021-06-25 22 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT04211909
Study to Investigate the Efficacy and Safety of Sofosbuvir/Velpatasvir (SOF/VEL) Fixed-Dose Combination (FDC) and Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX ) FDC for 12 Weeks in Adults With Chronic Hepatitis C Virus (HCV) Infection
Not yet reported Gilead Sciences 87 participants Est. completion 2020-11-12 22 sitesOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Completed NCT NCT04382404
Treatment of Chronic Hepatitis C During Pregnancy With Sofosbuvir/Velpatasvir
Not yet reported Catherine Anne Chappell 11 participants Est. completion 2023-10-16 1 site Stand-aloneOther conditions: Hepatitis C, ChronicView official trial listing → -
Completed NCT NCT04653818
HCV Related Hepatocellular Carcinoma Recurrence After Directly Acting Antivirals: A Randomized Controlled Trial
Not yet reported Alexandria University 84 participants Est. completion 2022-10-24 1 siteOther conditions: Hepatocellular Carcinoma, Hepatitis C, Neoplasm Recurrence, Treatment ComplicationView official trial listing → -
Status unknown NCT NCT04662138
Safety and Efficacy of Different Antiviral Regimens for Hepatitis C Virus Relapse
Alexandria University 100 participants Est. completion 2022-05-28 1 siteOther conditions: Hepatitis C, Relapse, AntiviralsView official trial listing → -
Completed NCT NCT04664894
Direct Acting Anti-Viral's In Chronic HCV Patients
Getz Pharma 511 participants Est. completion 2019-05-30 1 siteOther conditions: Safety IssuesView official trial listing → -
Completed NCT NCT04695769
Combined Ribavirin With Sofosbuvir/Velpatasvir/Voxilaprevir in Retreatment of Chronic Hepatitis C Non-responders
Not yet reported Helwan University 281 participants Est. completion 2021-10-21 1 site Stand-aloneOther conditions: Chronic Hepatitis CView official trial listing → -
Status unknown NCT NCT04948801
SOF/VEL±RBV: Efficacy and Safety in GT 3 and 6 HCV Patients
Third Affiliated Hospital, Sun Yat-Sen University 150 participants Est. completion 2021-12-30 1 siteOther conditions: Hepatitis CView official trial listing → -
Status unknown NCT NCT04952207
Effectiveness and Safety of Direct-Acting Antiviral Agents for the Treatment of Chronic Hepatitis C
Qing XIe 300 participants Est. completion 2021-08-31 11 sitesOther conditions: Hepatitis C, ChronicView official trial listing → -
Status unknown NCT NCT04997564
The Efficacy and Safety of 12-week SOF/VEL Regimen Combined With Prophylactic Use of TAF for Treatment-naïve Genotype 1-6 HCV/HBV Co-infection Adult Patients With or Without Compensated Cirrhosis in China
Not yet reported Peking University First Hospital 120 participants Est. completion 2023-12 1 site Stand-aloneOther conditions: Chronic Hepatitis C, Chronic Hepatitis BView official trial listing → -
Status unknown NCT NCT05016609
Same-visit Hepatitis C Testing and Treatment (The QuickStart Study)
Not yet reported Macfarlane Burnet Institute for Medical Research and Public Health Ltd 1800 participants Est. completion 2024-06 6 sites Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Status unknown NCT NCT05092074
Sofosbuvir/Velpatasvir/Voxilaprevir (SOF/VEL/VOX) for Patients With Hepatitis C Virus Infection
National Taiwan University Hospital 100 participants Est. completion 2023-02-28 15 sitesOther conditions: Hepatitis C Virus Infection, Treatment Side Effects, Adherence, Treatment, Effect of DrugView official trial listing → -
Active, not recruiting NCT NCT05140941
Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy
Not yet reported Catherine Anne Chappell 100 participants Est. completion 2027-06 9 sites Stand-aloneOther conditions: Hepatitis C, Chronic, Pregnancy; InfectionView official trial listing → -
Enrolling by invitation NCT NCT05248919
Therapy for Hepatitis C Virus (HCV) in Primary Treatment Failure in Pakistan
Not yet reported Queen Mary University of London 318 participants Est. completion 2027-09 1 siteOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT05264558
Preparing for the Final Phase of Hepatitis C Elimination. Cairns Final 30%
Not yet reported Macfarlane Burnet Institute for Medical Research and Public Health Ltd 606 participants Est. completion 2023-09-30 1 site Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Status unknown NCT NCT05467826
Efficacy and Safety of SOF/VEL + RBV and SOF/VEL/VOX for 12 Weeks in HCV Subjects With GT3b and Compensated Cirrhosis
Not yet reported Peking University People's Hospital 100 participants Est. completion 2023-12-31 Stand-aloneOther conditions: Hepatitis C, CirrhosisView official trial listing → -
Status unknown NCT NCT05474781
Eliminating HCV Infection Among PWUD
Vancouver Infectious Diseases Centre 300 participants Est. completion 2024-12-31 1 siteOther conditions: Hepatitis C, Chronic, Drug UseView official trial listing → -
Status unknown NCT NCT05503979
Elimination of Hepatitis C Virus Among Users of Substances
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 1000 participants Est. completion 2024-05-15Other conditions: Hepatitis C in Substance UsersView official trial listing → -
Terminated NCT NCT05717400
Improving Response to Immunotherapy in Patients With Advanced Hepatocellular Carcinoma and Chronic Hepatitis C Virus Infection With Direct-Acting Antiviral Therapy
Not yet reported M.D. Anderson Cancer Center 2 participants Est. completion 2024-08-29 1 site Stand-aloneOther conditions: Liver CancerView official trial listing → -
Status unknown NCT NCT05895448
Treatment of HCV-Infected Recent Injection Drug Users in U.S. Liver Clinics
Not yet reported Center For Hepatitis C, Atlanta, GA 125 participants Est. completion 2024-01-01 1 site Stand-aloneOther conditions: Chronic Hepatitis C, People Who Inject DrugsView official trial listing → -
Status unknown NCT NCT06533319
Hepatitis C Treatment in Idaho County Jails
Not yet reported Eastern Idaho Public Health 100 participants Est. completion 2025-08-01Other conditions: Hepatitis CView official trial listing → -
Completed NCT NCT06829966
Impact of Direct-acting Antiviral Drugs on The Patterns of Gut Microbiota in Patients With HCV Related Chronic Liver Diseases
Assiut University 30 participants Est. completion 2024-08-30 1 siteOther conditions: Intestinal Microbiota Between Different GroupsView official trial listing → -
Active, not recruiting NCT NCT06868264
C-BEYOND: Efficacy and Safety of BEM/RZR vs. SOF/VEL in Subjects With Chronic HCV
Not yet reported Atea Pharmaceuticals, Inc. 880 participants Est. completion 2026-12 105 sitesOther conditions: HEPATITIS C VIRUS CHRONIC INFECTIONView official trial listing → -
Active, not recruiting NCT NCT07037277
C-Forward: Efficacy and Safety of BEM/RZR vs SOF/VEL in Subjects With Chronic HCV
Not yet reported Atea Pharmaceuticals, Inc. 880 participants Est. completion 2027-03 107 sitesOther conditions: HEPATITIS C VIRUS CHRONIC INFECTION, Hepatitis C, Chronic, Hepatitis C Virus Infection, Hepatitis CView official trial listing → -
Not yet recruiting NCT NCT07098481
Access to Hepatitis C Treatment in Cameroon: Comparison of a Simplified Test and Treat Strategy to a Standard Strategy
Not yet reported ANRS, Emerging Infectious Diseases 576 participants Est. completion 2028-06-30 Stand-aloneOther conditions: Hepatitis C Virus InfectionView official trial listing → -
Not yet recruiting NCT NCT07560046
Combating Related Epidemics in HCV
Not yet reported Duke University 1280 participants Est. completion 2030-12-30 Stand-aloneOther conditions: HIV - Human Immunodeficiency Virus, Hepatitis B Virus (HBV), HEPATITIS C (HCV)View official trial listing → -
Active, not recruiting NCT NCT07565948
Sofosbuvir/Velpatasvir/Voxilaprevir Salvage Therapy in Hepatitis C Patients Who Relapsed After DAA Treatment
Xiangya Hospital of Central South University 200 participants Est. completion 2027-12-31 1 siteOther conditions: Hepatitis C Virus (HCV)View official trial listing → -
Not yet recruiting NCT NCT07793643
AI-Powered Hepatitis C Single-Encounter Test-and-Treat
Not yet reported Patrick Grace 35 participants Est. completion 2028-09-01 1 site Stand-aloneOther conditions: HEPATITIS C (HCV)View official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Velpatasvir, Epclusa
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
