GLP-1 Market
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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Torsemide

Company
Sarfez Pharmaceuticals, Inc.
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
3 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

3 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Sep 29, 2026

Find a Clinical Trial Near Me

See recruiting studies for Torsemide and check eligibility with the study team.

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Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT06218199

    Diuretics vs. Afterload Reduction for Treatment of HeartLogic Alerts

    Not yet reported Heart Center Research, LLC 80 participants Est. completion 2026-12-31 1 site
    Heart failure
    View official trial listing →
  • Recruiting NCT NCT07201584

    A Comparative Bioavailability Study of Two Torasemide 10 mg Tablets Formulations in Healthy Adult Participants Under Fasting Conditions:

    Not yet reported Berlin-Chemie AG Menarini Group 26 participants Est. completion 2026-04-01 1 site
    Other conditions: Healthy Adult Male and Female Volunteers
    View official trial listing →
  • Recruiting NCT NCT07684326

    "Exploring the Potential Benefits of Using Dapagliflozin in Cirrhotic Chronic Liver Disease Patients- A Randomized Controlled Trial"

    Not yet reported, Not yet reported Beni-Suef University 52 participants Est. completion 2027-09 1 site
    Other conditions: Ascites Hepatic
    View official trial listing →
  • Completed NCT NCT00295542

    Ambulatory Blood Pressure Monitoring in the Prediction of Cardiovascular Events and Effects of Chronotherapy

    Not yet reported University of Vigo 3344 participants Est. completion 2009-04 1 site
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT00334386

    Hypertension Study: Multinational Torasemide Trial in Mild to Moderate Hypertension.

    Not yet reported Ferrer Internacional S.A. 388 participants Est. completion 2006-02
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT00602303

    Bioequivalency Study of Torsemide Tablets Under Fasting Conditions

    Not yet reported Roxane Laboratories 28 participants Est. completion 2003-09 1 site
    Other conditions: Edema
    View official trial listing →
  • Completed NCT NCT00602615

    Bioequivalency Study of Torsemide Tablets Under Fed Conditions

    Not yet reported Roxane Laboratories 28 participants Est. completion 2003-09 1 site
    Other conditions: Edema
    View official trial listing →
  • Completed NCT NCT00653549

    Bioavailability Study of Torsemide Tablets Under Fasting Conditions

    Not yet reported Par Pharmaceutical, Inc. 26 participants Est. completion 2001-05 Stand-alone
    Other conditions: To Determine Bioequivalence Under Fasting Conditions
    View official trial listing →
  • Completed NCT NCT00654043

    Bioavailability Study of Torsemide Tablets Under Fed Conditions

    Not yet reported Par Pharmaceutical, Inc. 24 participants Est. completion 2001-05 Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00684489

    Renin-Guided Therapeutics in the Management of Untreated, Uncontrolled, or Complicated Hypertension

    Not yet reported Medical University of South Carolina 52 participants Est. completion 2005-09
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT00953303

    The Effects of Glucocorticoids on Mortality and Renal Function in Patients With Acute Decompensated Heart Failure

    Not yet reported, Not yet reported Hebei Medical University 102 participants Est. completion 2012-01 1 site
    Heart failure
    View official trial listing →
  • Completed NCT NCT01276288

    Pharmacodynamics and Pharmacokinetics of Empagliflozin and Torasemide in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 23 participants 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01457053

    Assessment of Coronary Flow Reserve in Heart Failure Patients After Ultrafiltration Versus Diuretics

    Not yet reported University of Cincinnati 4 participants Est. completion 2013-05 2 sites
    Heart failure
    View official trial listing →
  • Terminated NCT NCT01558674

    A Study of MK-7145 in Participants With Renal Insufficiency (Part I) and Heart Failure With Renal Insufficiency (Part II) (MK-7145-011)

    Not yet reported Merck Sharp & Dohme LLC 11 participants Est. completion 2014-12-17
    Heart failure Other conditions: Renal Impairment
    View official trial listing →
  • Withdrawn NCT NCT01663662

    The Use of Tolvaptan to Prevent Renal Dysfunction in High Risk Patients With Heart Failure-Pilot Study

    Not yet reported University of Michigan Est. completion 2013-11 1 site
    Heart failure
    View official trial listing →
  • Completed NCT NCT01788254

    Open Label Study for the Functional Characterization of Drug Metabolism and Transport

    Not yet reported Matthias Schwab 144 participants Est. completion 2015-05 2 sites Stand-alone
    Other conditions: Genotype-related Drug Metabolism
    View official trial listing →
  • Completed NCT NCT01845194

    Repeated Dose Study for the Investigation of Heritability of and Genetic Influences on Drug Pharmacokinetics

    Not yet reported Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH 117 participants Est. completion 2013-10 1 site Stand-alone
    Other conditions: Drug Biotransformation, Membrane Transport
    View official trial listing →
  • Status unknown NCT NCT01942109

    The Impact of TORasemide oN hemodynAmic and Neurohormonal Stress, and carDiac remOdeling in Heart Failure

    Not yet reported Medical University of Warsaw 100 participants Est. completion 2018-12 2 sites
    Heart failure
    View official trial listing →
  • Status unknown NCT NCT02087332

    Investigator Initiated Randomized Open-label Comparative Study of Britomar (Prolonged Release Torasemide) and Diuver (Torasemide) to Assess Effects on Natriuresis and Central Hemodynamics.

    Not yet reported Society of Specialists in Heart Failure 78 participants Est. completion 2015-05
    Heart failure Other conditions: Arterial Hypertension
    View official trial listing →
  • Completed NCT NCT02191358

    YouScript IMPACT Registry

    Genelex Corporation 800 participants Est. completion 2015-08 7 sites
    Other conditions: Adverse Drug Events, Adverse Drug Reactions, Drug Interaction Potentiation, Drug Metabolism, Poor, CYP2D6-RELATED, Drug Metabolism, Poor, CYP2C19-RELATED, Cytochrome P450 Enzyme Deficiency, Cytochrome P450 CYP2D6 Enzyme Deficiency, Cytochrome P450 CYP2C9 Enzyme Deficiency, Cytochrome P450 CYP2C19 Enzyme Deficiency, Cytochrome P450 CYP3A Enzyme Deficiency, Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant, Poor Metabolizer Due to Cytochrome P450 CYP2C19 Variant, Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant
    View official trial listing →
  • Terminated NCT NCT02288819

    Spot Urinary Analysis to Assess Loop Diuretic Efficiency in Stable Heart Failure

    Not yet reported Hasselt University 50 participants Est. completion 2016-04 1 site Stand-alone
    Heart failure
    View official trial listing →
  • Completed NCT NCT02813551

    ToRsemide for pOstpartum HYpertension

    Not yet reported The University of Texas Health Science Center, Houston 118 participants Est. completion 2017-09-09 1 site Stand-alone
    Other conditions: Preeclampsia
    View official trial listing →
  • Completed NCT NCT03187509

    Weight-Based Torsemide Dosing in Subjects With Heart Failure

    Not yet reported New York City Health and Hospitals Corporation 52 participants Est. completion 2022-03-14 1 site Stand-alone
    Heart failure
    View official trial listing →
  • Completed NCT NCT03214874

    Within Subject Variability Study of ER Torsemide 20 mg Tablet in Healthy Subjects

    Not yet reported Sarfez Pharmaceuticals, Inc. 24 participants Est. completion 2017-07-20 1 site Stand-alone
    Heart failureChronic kidney disease
    View official trial listing →
  • Completed NCT NCT03215875

    A Food Effect Study of 60mg ER Torsemide

    Not yet reported Sarfez Pharmaceuticals, Inc. 28 participants Est. completion 2018-03-31 1 site Stand-alone
    Other conditions: Food-drug Interaction
    View official trial listing →
  • Completed NCT NCT03296813

    TRANSFORM-HF: ToRsemide compArisoN With furoSemide FORManagement of Heart Failure

    Not yet reported Duke University 2973 participants Est. completion 2022-07-29 60 sites
    Heart failure
    View official trial listing →
  • Completed NCT NCT03354897

    Clinical Study of UMOD NKCC2 Interaction on Salt-sensitivity in Hypertension

    Not yet reported NHS Greater Glasgow and Clyde 228 participants Est. completion 2021-10-30 1 site
    Cardiovascular disease Other conditions: Hypertension
    View official trial listing →
  • Terminated NCT NCT03509545

    Comparison of Once Daily 40 mg Torsemide With Twice-daily 40 mg Furosemide

    Not yet reported Sarfez Pharmaceuticals, Inc. 20 participants Est. completion 2022-06-30 1 site Stand-alone
    Other conditions: Body Weight Changes
    View official trial listing →
  • Withdrawn NCT NCT04192110

    Association of Diuretics With Change in Extracellular Volume, Natriuretic Peptides, Symptoms, and Cardiovascular Outcomes in CKD

    Not yet reported VA Office of Research and Development Est. completion 2020-08-11 1 site Stand-alone
    Chronic kidney disease
    View official trial listing →
  • Completed NCT NCT04467931

    ACEI or ARB and COVID-19 Severity and Mortality in US Veterans

    University of Utah 22213 participants Est. completion 2020-12-31 1 site
    Other conditions: Hypertension, COVID
    View official trial listing →
  • Completed NCT NCT04702958

    TRANSFORM-HF Ancillary Mechanistic Study

    Inova Health Care Services 150 participants Est. completion 2023-05-30 9 sites
    Heart failure
    View official trial listing →
  • Completed NCT NCT04921566

    Bioequivalence Study of Two Formulations of Torasemide Tablet 10 mg in Healthy Volunteers Under Fasting Conditions

    Not yet reported Pharmtechnology LLC 26 participants Est. completion 2021-06-20 1 site
    Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT05093621

    Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure

    Not yet reported Yale University 47 participants Est. completion 2023-06-30 1 site
    Heart failure
    View official trial listing →
  • Completed NCT NCT05171686

    Diuretics and Volume Overload in Early CKD

    Not yet reported VA Office of Research and Development 49 participants Est. completion 2025-10-02 1 site Stand-alone
    Chronic kidney disease Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT06036914

    A Study of Ultra High Dose Diuretics to Treat Heart Failure

    Not yet reported Mayo Clinic 20 participants Est. completion 2024-10-08 1 site
    Heart failure
    View official trial listing →
  • Status unknown NCT NCT06037434

    Study of Innovative Drug Treatment Therapy for Pediatric Mitral Regurgitation

    China National Center for Cardiovascular Diseases 122 participants Est. completion 2024-12-31 1 site
    Other conditions: Congenital Mitral Insufficiency
    View official trial listing →
  • Status unknown NCT NCT06039540

    Study of Drug Therapy for Pediatric Heart Failure

    China National Center for Cardiovascular Diseases 200 participants Est. completion 2024-12-31 1 site
    Heart failure
    View official trial listing →
  • Status unknown NCT NCT06039592

    Study of Innovative Drug Strategies in Improving Left Ventricular Function After Mitral Repair

    China National Center for Cardiovascular Diseases 164 participants Est. completion 2024-12-31 1 site
    Other conditions: Congenital Mitral Insufficiency
    View official trial listing →
  • Withdrawn NCT NCT06176794

    Immediate Release Torsemide Versus Extended Release Torsemide After Salty Meal

    Not yet reported Sarfez Pharmaceuticals, Inc. Est. completion 2025-03-25 1 site Stand-alone
    Heart failure
    View official trial listing →
  • Completed NCT NCT06206512

    Effect of Extended Release Torsemide in Patients With Congestive Heart Failure and Overactive Bladder

    Not yet reported Sarfez Pharmaceuticals, Inc. 24 participants Est. completion 2026-03-09 1 site Stand-alone
    Heart failure Other conditions: Overactive Bladder, Incontinence
    View official trial listing →
  • Status unknown NCT NCT06275763

    Optimal Medical Treatment of Difficult-to-treat Hypertension

    Not yet reported National Institute of Cardiology, Warsaw, Poland 2500 participants Est. completion 2025-12-31 1 site
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT06292091

    A Study to Investigate the Effect of Urine Acid-base Disequilibrium on the Pharmacokinetics of Captopril

    Not yet reported Seoul National University Hospital 12 participants Est. completion 2024-04-01 1 site Stand-alone
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT06362668

    EU Sites: Fluid Management of Acute Decompensated Heart Failure With Reprieve Decongestion Management System (FASTR-EU)

    Not yet reported Reprieve Cardiovascular, Inc 12 participants Est. completion 2024-10-31 2 sites
    Heart failure
    View official trial listing →
  • Completed NCT NCT06413082

    Pharmacogenetics of Torasemide and Spironolactone in Hypertension Treatment

    Not yet reported Ospedale San Raffaele 38 participants Est. completion 2023-09-03 2 sites
    Other conditions: Hypertension, Genetic Predisposition, Drug Effect
    View official trial listing →
  • Status unknown NCT NCT06414759

    Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Volume Overload

    Not yet reported Cairo University 110 participants Est. completion 2025-03-30 1 site Stand-alone
    Heart failure Other conditions: Volume Overload, Edema
    View official trial listing →
  • Withdrawn NCT NCT06708611

    A Crossover Study of Patients With HF to Compare Natriuretic Effects of IR Torsemide vs. ER Torsemide Over 12 Hrs

    Not yet reported Sarfez Pharmaceuticals, Inc. Est. completion 2025-03-25 1 site Stand-alone
    Heart failure
    View official trial listing →
  • Withdrawn NCT NCT06995144

    Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart Failure

    Not yet reported Sarfez Pharmaceuticals, Inc. Est. completion 2026-09-16 1 site
    Heart failure Other conditions: Edema, Pulmonary Congestion, Fluid Overload
    View official trial listing →
  • Completed NCT NCT07015671

    Bioavailability and Bioequivalence Study of ER Torsemide and Spironolactone FDC Tablet in Healthy Subjects

    Not yet reported Sarfez Pharmaceuticals, Inc. 24 participants Est. completion 2025-12-30 1 site Stand-alone
    Other conditions: Bioequivalence Study in Healthy Subjects, PK/PD
    View official trial listing →
  • Completed NCT NCT07043634

    A Study to Evaluate the Effect of Food or no Food on the Bioavailability of an Extended Release (ER) Torsemide and Spironolactone Fixed Dose Combination (FDC) Tablet in Healthy Adult Subjects

    Not yet reported Sarfez Pharmaceuticals, Inc. 24 participants Est. completion 2025-12-30 1 site
    Other conditions: Bioavailability Heathy Volunteers
    View official trial listing →
  • Completed NCT NCT07046975

    Bioavailability and Bioequivalence Study of Extended Release Torsemide and Spironolactone

    Not yet reported Sarfez Pharmaceuticals, Inc. 24 participants Est. completion 2026-02-28 1 site
    Other conditions: Bioavailability Heathy Volunteers
    View official trial listing →
  • Withdrawn NCT NCT07223502

    A Study Comparing the Clinical Benefit of Finerenone Versus a Fixed Dose Combination (FDC) of Extended-Release Torsemide and Spironolactone in Patients With Hypertension and Chronic Kidney Disease

    Not yet reported Sarfez Pharmaceuticals, Inc. Est. completion 2026-09-17 1 site
    Other conditions: Hypertension (HTN)
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: Torsemide, Extended Release Torsemide Tablets, ER Torsemide

Related On The Pen coverage

No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.