About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Sirolimus
- Company
- National Human Genome Research Institute (NHGRI)
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 189 recruiting
Efficacy results: Not yet reported
189 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 1, 2026
Find a Clinical Trial Near Me
See recruiting studies for Sirolimus and check eligibility with the study team.
Trial details
-
Recruiting NCT NCT01241864
Islet Transplantation in Type 1 Diabetic Kidney Allograft
Not yet reported University of Chicago 10 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Recruiting NCT NCT02029001
Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment
Not yet reported Centre Leon Berard 900 participants Est. completion 2028-10 7 sitesOther conditions: Malignant Solid NeoplasmsView official trial listing → -
Recruiting NCT NCT02042326
Prospective Evaluation of the Efficacy of Sirolimus (Rapamune®) in the Treatment of Severe Arteriovenous Malformations
Not yet reported Centre Hospitalier Universitaire, Amiens 50 participants Est. completion 2027-09 13 sites Stand-aloneOther conditions: Arteriovenous MalformationsView official trial listing → -
Recruiting NCT NCT02432560
Safety and Durability of Sirolimus for Treatment of LAM
University of Cincinnati 600 participants Est. completion 2025-07-31 20 sitesOther conditions: LymphangioleiomyomatosisView official trial listing → -
Recruiting NCT NCT02446431
Metronomic Therapy for Pediatric Patients With Solid Tumors at High Risk of Recurrence
Not yet reported Miller Children's & Women's Hospital Long Beach 20 participants Est. completion 2029-07 2 sites Stand-aloneOther conditions: Solid TumorView official trial listing → -
Recruiting NCT NCT02579967
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
Not yet reported National Cancer Institute (NCI) 354 participants Est. completion 2036-12-31 2 sites Stand-aloneOther conditions: Primary T-cell Immunodeficiency Disorders, Common Variable Immunodeficiency, Immune System Diseases, Autoimmune Lymphoproliferative, Lymphoproliferative DisordersView official trial listing → -
Recruiting NCT NCT02638389
Efficacy and Safety of Sirolimus in Vascular Anomalies That Are Refractory to Standard Care
Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 250 participants Est. completion 2030-04-01 3 sites Stand-aloneOther conditions: Vascular MalformationsView official trial listing → -
Recruiting NCT NCT02693535
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Not yet reported American Society of Clinical Oncology 4200 participants Est. completion 2028-12-31 181 sitesOther conditions: Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT02813135
European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors
Not yet reported, Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 472 participants Est. completion 2031-02 23 sitesOther conditions: Pediatric CancerView official trial listing → -
Recruiting NCT NCT03121001
Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease
Not yet reported University of Illinois at Chicago 50 participants Est. completion 2029-05 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Recruiting NCT NCT03214354
Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor
Not yet reported University of Calgary 12 participants Est. completion 2028-07 1 site Stand-aloneOther conditions: Sickle Cell Disease, Stem Cell Transplant Complications, Red Blood Cell Disorder, Pure Red Cell AplasiaView official trial listing → -
Recruiting NCT NCT03243019
Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations
Not yet reported University Hospital, Lille 28 participants Est. completion 2027-02 2 sites Stand-aloneOther conditions: Lymphatic Malformation, PediatricView official trial listing → -
Recruiting NCT NCT03297606
Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)
Not yet reported Canadian Cancer Trials Group 720 participants Est. completion 2027-01-31 10 sitesOther conditions: Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT03443999
S-FLEX Netherlands Registry: Prospective Evaluation of the Supraflex Family Sirolimus-eluting Coronary Stent System
Sahajanand Medical Technologies Limited 10000 participants Est. completion 2027-12 7 sitesCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT03587272
Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease
Not yet reported Robert Nickel 100 participants Est. completion 2030-11 7 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Recruiting NCT NCT03952637
A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis
Not yet reported, Not yet reported National Human Genome Research Institute (NHGRI) 54 participants Est. completion 2030-01-01 1 site Stand-aloneOther conditions: Lysosomal Diseases, Gangliosidosis, GM1View official trial listing → -
Recruiting NCT NCT03955172
Efficiency of Everolimus for the Treatment of Kidney Transplanted Patients Presenting a Missing Self-induced NK-mediated Rejection
Not yet reported Hospices Civils de Lyon 20 participants Est. completion 2027-12-03 1 siteOther conditions: Kidney Transplant Failure and RejectionView official trial listing → -
Recruiting NCT NCT03970096
Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)
Not yet reported Fred Hutchinson Cancer Center 120 participants Est. completion 2029-12-31 3 sites Stand-aloneOther conditions: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative NeoplasmView official trial listing → -
Recruiting NCT NCT04022616
Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
Ohio State University Comprehensive Cancer Center 99 participants Est. completion 2027-12-31 1 siteOther conditions: Breast CancerView official trial listing → -
Recruiting NCT NCT04083183
Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant Diseases
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2028-01-09 1 site Stand-aloneOther conditions: Non-Malignant NeoplasmView official trial listing → -
Recruiting NCT NCT04141020
Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms
Not yet reported University of Miami 80 participants Est. completion 2026-11-01 1 site Stand-aloneOther conditions: Cerebral AneurysmView official trial listing → -
Recruiting NCT NCT04199026
Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma
Not yet reported M.D. Anderson Cancer Center 20 participants Est. completion 2028-12-31 1 siteOther conditions: Metastatic Sarcoma, Recurrent Sarcoma, Resectable SarcomaView official trial listing → -
Recruiting NCT NCT04433572
Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee
Not yet reported Mercator MedSystems, Inc. 250 participants Est. completion 2032-08-01 2 sitesOther conditions: Peripheral Artery Disease, Critical Limb IschemiaView official trial listing → -
Recruiting NCT NCT04469530
Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors
Not yet reported Emory University 55 participants Est. completion 2029-02 5 sites Stand-aloneOther conditions: Solid TumorView official trial listing → -
Recruiting NCT NCT04485559
Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)
Not yet reported University of California, San Francisco 50 participants Est. completion 2027-12-31 17 sitesOther conditions: Recurrent World Health Organization (WHO) Grade II Glioma, Low-grade Glioma, High-Grade Glioma (HGG)View official trial listing → -
Recruiting NCT NCT04511234
Sirolimus Coated Balloon Versus Standard Balloon for SFA and Popliteal Artery Disease
Not yet reported Concept Medical Inc. 279 participants Est. completion 2026-12 20 sites Stand-aloneOther conditions: Peripheral Artery Disease, Atherosclerosis, Arterial DiseaseView official trial listing → -
Recruiting NCT NCT04511247
SirolimUs CoaTed Balloon for The TrEatment of Below The Knee Arterial Disease
Not yet reported Concept Medical Inc. 219 participants Est. completion 2027-12 20 sites Stand-aloneOther conditions: Peripheral Artery Disease, Atherosclerosis, Arterial Disease of LegsView official trial listing → -
Recruiting NCT NCT04584632
The Efemoral Vascular Scaffold System (EVSS) for the Treatment of Patients With Symptomatic Peripheral Vascular Disease From Stenosis or Occlusion of the Femoropopliteal Artery
Not yet reported Efemoral Medical, Inc. 100 participants Est. completion 2030-03 8 sites Stand-aloneOther conditions: Peripheral Arterial Disease, Vascular Diseases, Stenosis, Femoropopliteal StenosisView official trial listing → -
Recruiting NCT NCT04665739
Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors
Not yet reported National Cancer Institute (NCI) 70 participants Est. completion 2027-07-01 29 sitesOther conditions: Advanced Lung Neuroendocrine Tumor, Functioning Lung Neuroendocrine Tumor, Locally Advanced Lung Neuroendocrine Neoplasm, Lung Neuroendocrine Neoplasm, Lung Neuroendocrine Tumor G1, Lung Neuroendocrine Tumor G2, Metastatic Lung Neuroendocrine Neoplasm, Metastatic Lung Neuroendocrine Tumor, Non-Functioning Lung Neuroendocrine Tumor, Recurrent Lung Neuroendocrine Neoplasm, Unresectable Lung Neuroendocrine Neoplasm, Unresectable Lung Neuroendocrine TumorView official trial listing → -
Recruiting NCT NCT04679740
Resorbable Magnesium Scaffolds Registry
Biotronik AG 1106 participants Est. completion 2030-05 13 sitesCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT04802759
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
Not yet reported, Not yet reported Hoffmann-La Roche 316 participants Est. completion 2029-05-30 32 sitesOther conditions: Inoperable, Locally Advanced or Metastatic, ER-positive Breast CancerView official trial listing → -
Recruiting NCT NCT04803318
Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors
Not yet reported Second Affiliated Hospital of Guangzhou Medical University 100 participants Est. completion 2037-01-01 1 siteOther conditions: Solid Tumor, Adult, Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT04861064
Weekly Sirolimus Therapy
Not yet reported Medical University of South Carolina 24 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Venous Malformation, Lymphatic MalformationView official trial listing → -
Recruiting NCT NCT04888741
Methods of T Cell Depletion Trial (MoTD)
Not yet reported University of Birmingham 400 participants Est. completion 2027-08-23 17 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Chronic Myelogenous Leukemia, MyelofibrosisView official trial listing → -
Recruiting NCT NCT04923191
The PIONEER-IV Study is Comparing Clinical Outcomes Between Angiography-derived Physiology Guidance to Usual Care in an All-comers PCI Population With Unrestrictive Use of the HT Supreme Sirolimus-eluting Stent
Not yet reported National University of Ireland, Galway, Ireland 2540 participants Est. completion 2029-01 19 sitesCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT04936854
Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease
Not yet reported Haukeland University Hospital 60 participants Est. completion 2028-12 1 siteOther conditions: Thyroid-Associated OphthalmopathyView official trial listing → -
Recruiting NCT NCT04948749
Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial
Not yet reported Beijing Tiantan Hospital 358 participants Est. completion 2027-12 18 sites Stand-aloneCardiovascular disease Other conditions: ICAD - Intracranial Atherosclerotic Disease, ICAS - Intracranial Atherosclerosis, Drug-eluting Stent, Drug Eluting Stents (DES), Medical TreatmentView official trial listing → -
Recruiting NCT NCT04959175
Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies
Not yet reported, Not yet reported National Cancer Institute (NCI) 320 participants Est. completion 2027-04-30 2 sites Stand-aloneOther conditions: Hematologic NeoplasmsView official trial listing → -
Recruiting NCT NCT04988685
SIROOP Registry - A Prospective Registry Study to Evaluate the Outcomes of Coronary Artery Disease Patients Treated With SIROlimus Or Paclitaxel Eluting Balloon Catheters
Luzerner Kantonsspital 2000 participants Est. completion 2031-12-31 1 siteCardiovascular disease Other conditions: Coronary Disease, Coronary Restenosis, Coronary Arteriosclerosis, Coronary Artery Calcification, Stable Chronic Angina, Angina Pectoris, Angina, Stable, Angina, Unstable, Stent ThrombosisView official trial listing → -
Recruiting NCT NCT05009992
Combination Therapy for the Treatment of Diffuse Midline Gliomas
Not yet reported University of California, San Francisco 360 participants Est. completion 2029-06-30 32 sitesOther conditions: Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, H3 K27M-Mutant, Recurrent Diffuse Intrinsic Pontine Glioma, Recurrent Diffuse Midline Glioma, H3 K27M-Mutant, Recurrent WHO Grade III Glioma, WHO Grade III GliomaView official trial listing → -
Recruiting NCT NCT05036226
COAST Therapy in Advanced Solid Tumors and Prostate Cancer
Not yet reported, Not yet reported Medical University of South Carolina 76 participants Est. completion 2028-05-21 1 site Stand-aloneOther conditions: Prostate Cancer Recurrent, Solid Tumor, AdultView official trial listing → -
Recruiting NCT NCT05104983
Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study
Not yet reported Darcy Krueger 64 participants Est. completion 2027-06-30 11 sites Stand-aloneOther conditions: Tuberous Sclerosis Complex, EpilepsyView official trial listing → -
Recruiting NCT NCT05105152
PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML
Not yet reported Seattle Children's Hospital 18 participants Est. completion 2041-01-31 1 siteOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, in RelapseView official trial listing → -
Recruiting NCT NCT05144698
RAPA-201 Therapy of Solid Tumors
Not yet reported, Not yet reported Rapa Therapeutics LLC 37 participants Est. completion 2026-12-31 1 siteOther conditions: Solid Tumor, Small Cell and Non-small Cell Lung Cancer, Head and Neck Cancer, Squamous Cell Carcinoma of Oral Cavity, Squamous Cell Carcinoma of Larynx, Squamous Cell Carcinoma of Nasopharynx, Squamous Cell Carcinoma of Other Specified Sites of Skin, Malignant Melanoma, Esophageal Squamous Cell CarcinomaView official trial listing → -
Recruiting NCT NCT05233722
mTOR as Mediator of Insulin Sensitivity Study
Not yet reported University of Copenhagen 10 participants Est. completion 2029-06 1 siteOther conditions: Insulin SensitivityView official trial listing → -
Recruiting NCT NCT05237687
The Role of Sirolimus in Preventing Functional Decline in Older Adults
Not yet reported Irina Timofte 10 participants Est. completion 2028-01 1 site Stand-aloneOther conditions: AgingView official trial listing → -
Recruiting NCT NCT05327023
Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies
Not yet reported, Not yet reported National Cancer Institute (NCI) 430 participants Est. completion 2029-07-02 1 site Stand-aloneOther conditions: Hematologic NeoplasmsView official trial listing → -
Recruiting NCT NCT05351216
The Effect of Sirolimus on Immunizations During the Treatment of Kaposiform Hemangioendothelioma
Children's Hospital of Fudan University 174 participants Est. completion 2028-03 1 siteOther conditions: Kaposiform HemangioendotheliomaView official trial listing → -
Recruiting NCT NCT05414292
Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune)
Not yet reported University of Nottingham 16 participants Est. completion 2027-05-01 1 site Stand-aloneOther conditions: Muscle Atrophy, Age-Related SarcopeniaView official trial listing → -
Recruiting NCT NCT05426252
Thal-Fabs: Reduced Toxicity Conditioning for High Risk Thalassemia
Not yet reported, Not yet reported The Hospital for Sick Children 20 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Thalassemia in ChildrenView official trial listing → -
Recruiting NCT NCT05432518
Pilot Trial for Treatment of Recurrent Glioblastoma
Not yet reported AHS Cancer Control Alberta 10 participants Est. completion 2027-12-01 1 siteOther conditions: Glioblastoma, Recurrent Disease, Recurrent GlioblastomaView official trial listing → -
Recruiting NCT NCT05436418
The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation
Not yet reported, Not yet reported National Cancer Institute (NCI) 260 participants Est. completion 2028-06-25 2 sites Stand-aloneOther conditions: Peripheral Blood Stem Cell Transplantation, Hematopoietic Stem Cell TransplantationView official trial listing → -
Recruiting NCT NCT05444452
GENOSS Coronary Stent Clinical Trial
Not yet reported Samsung Medical Center 850 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Ischemic Heart DiseaseView official trial listing → -
Recruiting NCT NCT05463133
Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 50 participants Est. completion 2032-12-31 1 site Stand-aloneOther conditions: Chronic Granulomatous DiseaseView official trial listing → -
Recruiting NCT NCT05476939
Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 433 participants Est. completion 2031-09 53 sitesOther conditions: Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, H3 K27M-Mutant, Diffuse Midline Glioma, H3K27-alteredView official trial listing → -
Recruiting NCT NCT05477576
Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy
Not yet reported RayzeBio, Inc. 338 participants Est. completion 2030-12 54 sitesOther conditions: GEP-NET, Gastroenteropancreatic Neuroendocrine Tumor, Gastroenteropancreatic Neuroendocrine Tumor Disease, Neuroendocrine Tumors, Carcinoid, Carcinoid Tumor, Pancreatic NETView official trial listing → -
Recruiting NCT NCT05534672
Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex
Not yet reported Katarzyna Kotulska 200 participants Est. completion 2027-06 2 sitesOther conditions: Tuberous Sclerosis ComplexView official trial listing → -
Recruiting NCT NCT05549167
Efficacy and Safety of Sirolimus in Children and Adolescents With Juvenile Nasopharyngeal Angiofibroma (JNA)
Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 117 participants Est. completion 2029-12-30 1 site Stand-aloneOther conditions: Juvenile Nasopharyngeal AngiofibromaView official trial listing → -
Recruiting NCT NCT05573126
Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer
Not yet reported, Not yet reported Ellipses Pharma 95 participants Est. completion 2028-02 14 sitesOther conditions: Hormone Receptor-positive Breast Cancer, Hormone Receptor Positive HER-2 Negative Breast Cancer, Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT05594095
SNF Platform Study of HR+/ HER2-advanced Breast Cancer
Not yet reported Fudan University 620 participants Est. completion 2026-12-01 1 siteOther conditions: Breast Neoplasm, Breast Cancer, Hormone Receptor Positive Tumor, HER2-negative Breast Cancer, Advanced Breast CancerView official trial listing → -
Recruiting NCT NCT05627960
First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies
Not yet reported A&G Pharmaceutical Inc. 77 participants Est. completion 2026-11 1 siteOther conditions: Triple Negative Breast Cancer, Hormone-Resistant Breast Cancer, Non Small Cell Lung Cancer, MesotheliomaView official trial listing → -
Recruiting NCT NCT05643872
A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita
Not yet reported Palvella Therapeutics, Inc. 45 participants Est. completion 2023-11 1 siteOther conditions: Pachyonychia CongenitaView official trial listing → -
Recruiting NCT NCT05650411
Ultrathin-strut Biodegradable Polymer Sirolimus-eluting Stents With P2Y12 Inhibitor-based Single Antiplatelet Therapy vs. Conventional DAPT for Unprotected Left Main Coronary Artery Disease (ULTIMATE-LM)
Not yet reported IGLESIAS Juan Fernando 828 participants Est. completion 2032-05-01 1 site Stand-aloneOther conditions: Left Main Coronary Artery StenosisView official trial listing → -
Recruiting NCT NCT05661461
Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment
Not yet reported Aadi Bioscience, Inc. 28 participants Est. completion 2026-08-01 2 sites Stand-aloneOther conditions: Tumor, Solid, Tumor, Advanced Solid TumorView official trial listing → -
Recruiting NCT NCT05692882
A Registry Study of Intracranial Atherosclerotic Stenosis Treatment by Intracranial Drug-eluting Stenting in China
Not yet reported Sino Medical Sciences Technology Inc. 1000 participants Est. completion 2029-12-30 5 sites Stand-aloneOther conditions: Intracranial Arteriosclerosis, Stenosis Artery, Drug-Eluting Stents, Intracranial Artery StenosisView official trial listing → -
Recruiting NCT NCT05725200
Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer
Not yet reported Oslo University Hospital 40 participants Est. completion 2040-12-31 1 siteOther conditions: Metastatic Colorectal CancerView official trial listing → -
Recruiting NCT NCT05731687
Bifurcation PCI With a Hybrid Strategy With Drug Eluting Balloons Versus a Stepwise Provisional Two-stent Strategy
Not yet reported Cathreine BV 500 participants Est. completion 2030-03 1 siteCardiovascular disease Other conditions: Coronary Bifurcation LesionView official trial listing → -
Recruiting NCT NCT05749588
FUSCC Refractory TNBC Platform Study (FUTURE2.0)
Not yet reported Fudan University 120 participants Est. completion 2028-12-31 1 siteOther conditions: Triple-negative Breast CancerView official trial listing → -
Recruiting NCT NCT05773274
Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial
Not yet reported National Cancer Institute (NCI) 100 participants Est. completion 2029-04-30 40 sitesOther conditions: Metastatic Digestive System Neuroendocrine Tumor G1, Metastatic Digestive System Neuroendocrine Tumor G2, Unresectable Digestive System Neuroendocrine Tumor G1, Unresectable Digestive System Neuroendocrine Tumor G2View official trial listing → -
Recruiting NCT NCT05785897
STEMI Treated With a Polymer-free Sirolimus-coated Stent and P2Y12 Inhibitor-based SAPT Versus Conventional DAPT
Not yet reported IGLESIAS Juan Fernando 350 participants Est. completion 2028-03-01 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT05805605
Allo HSCT Using RIC and PTCy for Hematological Diseases
Not yet reported Masonic Cancer Center, University of Minnesota 56 participants Est. completion 2028-10-22 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Biphenotypic Acute Leukemia, Undifferentiated Leukemia, Prolymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Myelodysplastic Syndrome With Excess Blasts-1, Burkitt Lymphoma, Relapsed T-Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone Lymphoma, Follicular Lymphoma, Myeloproliferative Neoplasm, MyelofibrosisView official trial listing → -
Recruiting NCT NCT05843253
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Not yet reported Nationwide Children's Hospital 120 participants Est. completion 2034-08-28 20 sitesOther conditions: High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Anaplastic Astrocytoma, Glioblastoma, Glioblastoma Multiforme, Diffuse Midline Glioma, H3 K27M-Mutant, Metastatic Brain Tumor, WHO Grade III Glioma, WHO Grade IV Glioma, Diffuse Hemispheric Glioma, H3 G34-MutantView official trial listing → -
Recruiting NCT NCT05885932
Drug-eluting Stenting Versus Medical Treatment for Extracranial Vertebral Artery Stenosis
Not yet reported Xuanwu Hospital, Beijing 472 participants Est. completion 2028-09-01 1 site Stand-aloneCardiovascular disease Other conditions: Vertebral Artery StenosisView official trial listing → -
Recruiting NCT NCT05896839
Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 16 participants Est. completion 2027-01-31 26 sites Stand-aloneOther conditions: Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8, Metastatic Basal Cell Carcinoma, Metastatic Carcinoma in the Skin, Metastatic Melanoma, Metastatic Merkel Cell Carcinoma, Metastatic Skin Squamous Cell Carcinoma, Unresectable Basal Cell Carcinoma, Unresectable Melanoma, Unresectable Merkel Cell Carcinoma, Unresectable Skin Squamous Cell CarcinomaView official trial listing → -
Recruiting NCT NCT05908331
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
Not yet reported Concept Medical Inc. 492 participants Est. completion 2028-07 28 sites Stand-aloneCardiovascular disease Other conditions: In-Stent RestenosisView official trial listing → -
Recruiting NCT NCT05918302
Efficacy and Safety of Radiotherapy Compared to Everolimus in Somatostatin Receptor Positive Neuroendocrine Tumors of the Lung and Thymus.
Not yet reported Grupo Espanol de Tumores Neuroendocrinos 170 participants Est. completion 2029-10 27 sitesOther conditions: Neuroendocrine Tumors, Lung Neuroendocrine Neoplasm, Thymus NeoplasmsView official trial listing → -
Recruiting NCT NCT05925023
Sirolimus in the Treatment of Refractory/Relapsed wAIHA
Not yet reported Peking Union Medical College Hospital 22 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: Warm Autoimmune Hemolytic AnemiaView official trial listing → -
Recruiting NCT NCT05933395
Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor
Not yet reported Dartmouth-Hitchcock Medical Center 135 participants Est. completion 2031-10 1 siteOther conditions: Advanced Breast CancerView official trial listing → -
Recruiting NCT NCT05949541
Efficacy of Everolimus Combined With First-line Endocrine Therapy for HR+/HER2- SNF1-subtype Advanced Breast Cancer
Not yet reported Fudan University 265 participants Est. completion 2028-01 1 siteOther conditions: Breast Cancer, Advanced Breast CancerView official trial listing → -
Recruiting NCT NCT05949658
Rapalog Pharmacology (RAP PAC) Study
Not yet reported University of Wisconsin, Madison 72 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: AgingView official trial listing → -
Recruiting NCT NCT05983107
Chidamide/Everolimus for PIK3CA Wild-type/Mutant HR+/HER2- Advanced Breast Cancer
Not yet reported Cancer Institute and Hospital, Chinese Academy of Medical Sciences 102 participants Est. completion 2027-07-15 1 siteOther conditions: HR+/HER2- Advanced Breast Cancer, Targeted TherapyView official trial listing → -
Recruiting NCT NCT05997017
Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer
Not yet reported Aadi Bioscience, Inc. 29 participants Est. completion 2027-06 9 sites Stand-aloneOther conditions: Endometrial Cancer, Endometrioid Tumor, Cancer, Tumor, Recurrent Endometrial Carcinoma, Endometrioid Endometrial CancerView official trial listing → -
Recruiting NCT NCT06018766
LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome.
Not yet reported Steven Hays, MD 30 participants Est. completion 2026-12 1 siteOther conditions: Bronchiolitis Obliterans Syndrome, Chronic Lung Allograft Dysfunction, Lung TransplantationView official trial listing → -
Recruiting NCT NCT06055608
Advancing Transplantation Outcomes in Children
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 200 participants Est. completion 2028-06-30 21 sites Stand-aloneOther conditions: Kidney TransplantView official trial listing → -
Recruiting NCT NCT06065852
National Registry of Rare Kidney Diseases
UK Kidney Association 35000 participants Est. completion 2039-12-31 1 siteAlcohol use disorder Other conditions: Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis, Alport Syndrome, Atypical Hemolytic Uremic Syndrome, Autoimmune Distal Renal Tubular Acidosis, Autosomal Recessive Proximal Renal Tubular Acidosis, Autosomal Recessive Distal Renal Tubular Acidosis, Autosomal Dominant Polycystic Kidney Disease, Autosomal Recessive Polycystic Kidney Disease, Bartter Syndrome, BK Nephropathy, C3 Glomerulopathy With Monoclonal Gammopathy, C3 Glomerulopathy, Calciphylaxis, Crystalglobulinaemia, Crystal-storing Histiocytosis, Cystinosis, Cystinuria, Dense Deposit Disease, Dent Disease, Denys-Drash Syndrome, Dominant Hypophosphataemia With Nephrolithiasis and/or Osteoporosis, Drug Induced Fanconi Syndrome, Drug-Induced Hypomagnesemia, Drug-Induced Nephrogenic Diabetes Insipidus, Epilepsy, Ataxia, Sensorineural Deafness and Tubulopathy, Fabry Disease, Familial Hypomagnesemia With Hypercalciuria and Nephrocalcinosis, Familial Primary Hypomagnesemia With Hypocalcuria, Familial Primary Hypomagnesaemia With Normocalciuria, Familial Renal Glucosuria, Fanconi Renotubular Syndrome 1, Fanconi Renotubular Syndrome 2, Fanconi Renotubular Syndrome 3, Fibrillary Glomerulonephritis, Fibromuscular Dysplasia, Focal Segmental Glomerulosclerosis, Generalised Pseudohypoaldosteronism Type 1, Gitelman Syndrome, Heavy-Metal-Induced Fanconi Syndrome, Hepatocyte Nuclear Factor 1-Beta-Associated Monogenic Diabetes, Hereditary Renal Hypouricemia, Hereditary Hypophosphatemic Rickets With Hypercalciuria, Hyperuricaemic Nephropathy, IgA Nephropathy, Immunotactoid Glomerulonephritis With Organised Microtubular Mononoclonal Immunoglobulin Deposits, Inherited Renal Cancer Syndromes, Intracapillary Monoclonal IgM Without Cryoglobulin, Intraglomerular/Capillary Lymphoma/Leukaemia, Liddle Syndrome, Light Chain Cast Nephropathy, Light Chain Proximal Tubulopathy Without Crystals, Light Chain Proximal Tubulopathy With Crystals, Lowe Syndrome, Membranous Nephropathy, Membranoproliferative Glomerulonephritis, Medullary Cystic Kidney Disease, Minimal Change Nephropathy, Mitochondrial Disease Of The Kidney, Monoclonal Immunoglobulin Deposition Disease, Nail Patella Syndrome, Nephrogenic Diabetes Insipidus, Nephrogenic Syndrome of Inappropriate Antidiuresis, Nephronophthisis, Primary Hypomagnesemia With Secondary Hypocalcemia, Primary Hyperoxaluria, Proliferative Glomerulonephritis With Monoclonal IgG Deposits, Proximal Tubulopathy Without Crystals, Pseudohypoaldosteronism Type 1, 2A-2E, Pure Red Cell Aplasia, Retroperitoneal Fibrosis, Sickle Cell Nephropathy, Shiga Toxin Associated Haemolytic Uraemic Syndrome, Steroid Resistant Nephrotic Syndrome, Steroid-Sensitive Nephrotic Syndrome, Thin Basement Membrane Nephropathy, Thrombotic Microangiopathy With Monoclonal Gammopathy, Type 1 Cryoglobulinaemic Glomerulonephritis, Tuberous Sclerosis, Unclassified Monoclonal Gammopathy Of Renal Significance, VasculitisView official trial listing → -
Recruiting NCT NCT06066450
Efficacy of OSFIT Drug-Eluting Stent in Coronary Ostial Artery Stenosis
Genoss Co., Ltd. 1000 participants Est. completion 2026-12-31 1 siteCardiovascular disease Other conditions: Drug-eluting StentView official trial listing → -
Recruiting NCT NCT06071429
Bioresorbable Sirolimus-Eluting Scaffold Treatment for Below the Knee Disease
Not yet reported R3 Vascular Inc. 300 participants Est. completion 2032-03-01 3 sites Stand-aloneOther conditions: Chronic Limb-Threatening IschemiaView official trial listing → -
Recruiting NCT NCT06075420
Efficacy and Safety of Short Duration of DAPT After GENOSS® DES Implantation in Patients with Coronary Artery Disease
Genoss Co., Ltd. 1000 participants Est. completion 2027-12-31 1 siteOther conditions: Percutaneous Coronary Intervention, Dual Antiplatelet TherapyView official trial listing → -
Recruiting NCT NCT06075433
Efficacy and Safety of 1-year Duration of DAPT After GENOSS® DES Implantation in Patients with Coronary Artery Disease According to the Complex Higher-risk Procedure
Genoss Co., Ltd. 1000 participants Est. completion 2027-12-31 1 siteCardiovascular disease Other conditions: Percutaneous Coronary Intervention, Dual Antiplatelet TherapyView official trial listing → -
Recruiting NCT NCT06091332
Hemorrhagic Brainstem Cavernous Malformations Treatment With Sirolimus: aSingle Centre, Randomized, Placebo-controlled Pilot Trial
Not yet reported Huashan Hospital 75 participants Est. completion 2026-12-31 2 sites Stand-aloneCardiovascular disease Other conditions: Cavernous Malformations, Intracerebral HemorrhageView official trial listing → -
Recruiting NCT NCT06126588
Combination of Everolimus and 177Lu-DOTATATE in the Treatment of Grades 2 and 3 Refractory Meningioma: a Phase IIb Clinical Trial
Not yet reported Central Hospital, Nancy, France 28 participants Est. completion 2028-05-01 2 sitesOther conditions: MeningiomaView official trial listing → -
Recruiting NCT NCT06182397
Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease
Not yet reported Concept Medical Inc. 368 participants Est. completion 2031-02-01 29 sitesOther conditions: Arterial Disease of Legs, Below-the-knee Obstruction, PAD - Peripheral Arterial DiseaseView official trial listing → -
Recruiting NCT NCT06211790
Proteomic Guided First-line Precision Treatment of Renal Clear Cell Carcinoma
Not yet reported Fudan University 66 participants Est. completion 2026-12-30 1 siteOther conditions: Kidney Cancer, Renal Cell Carcinoma, Renal Clear Cell CarcinomaView official trial listing → -
Recruiting NCT NCT06236022
The Effects of Sirolimus in Patients With Dilated Cardiomyopathy Infected With Kaposi Sarcoma-associated Virus
Not yet reported Tongji Hospital 276 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Dilated Cardiomyopathy, Kaposi's Sarcoma-Associated Herpesvirus InfectionView official trial listing → -
Recruiting NCT NCT06271590
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels
Not yet reported Concept Medical Inc. 1605 participants Est. completion 2031-11 24 sites Stand-aloneCardiovascular disease Other conditions: Native Coronary Artery StenosisView official trial listing → -
Recruiting NCT NCT06280950
Expanding Liver Transplant Immunosuppression Minimization Via Everolimus
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 340 participants Est. completion 2030-06-30 12 sitesOther conditions: Liver TransplantView official trial listing → -
Recruiting NCT NCT06287944
225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome
Not yet reported City of Hope Medical Center 15 participants Est. completion 2028-05-19 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT06310291
VTP-1000 in Adults With Celiac Disease
Not yet reported Barinthus Biotherapeutics 45 participants Est. completion 2026-11 16 sitesOther conditions: Celiac DiseaseView official trial listing → -
Recruiting NCT NCT06325709
Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 15 participants Est. completion 2032-12-31 1 site Stand-aloneOther conditions: Chronic Granulomatous Disease (CGD), X-Linked Chronic Granulomatous DiseaseView official trial listing → -
Recruiting NCT NCT06326190
177Lu-DOTATATE for Recurrent Meningioma
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 136 participants Est. completion 2028-12-22 19 sitesOther conditions: Recurrent MeningiomaView official trial listing → -
Recruiting NCT NCT06358638
Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody
Not yet reported Children's National Research Institute 12 participants Est. completion 2054-09 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Recruiting NCT NCT06373601
SPAGO: Sirolimus Paclitaxel Angiographic Gain Objective
Not yet reported Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS 140 participants Est. completion 2027-08-01 10 sites Stand-aloneCardiovascular disease Other conditions: Stenosis Coronary, Coronary Artery Lesion, Percutaneous Coronary InterventionView official trial listing → -
Recruiting NCT NCT06382948
Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.
Not yet reported MedSIR 300 participants Est. completion 2028-04 104 sitesOther conditions: Advanced Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, ESR1 Gene MutationView official trial listing → -
Recruiting NCT NCT06412250
A Multicenter Observational Registry to Evaluate Safety and Performance of Vivo ISAR (SECURE Global Registry)
Translumina Therapeutics Pvt Ltd. 2000 participants Est. completion 2027-11 32 sitesCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT06420505
Evaluation of the Vivo Isar Stent System in Routine Clinical Practice
Translumina GmbH 3000 participants Est. completion 2027-01-01 19 sitesOther conditions: Artery Coronary StenosisView official trial listing → -
Recruiting NCT NCT06437574
Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer
Not yet reported Cedars-Sinai Medical Center 140 participants Est. completion 2028-05-31 1 siteOther conditions: Prostate CancerView official trial listing → -
Recruiting NCT NCT06472388
Everolimus 5 mg vs 10 mg/Daily for Patients With Neuroendocrine Tumors
Not yet reported AC Camargo Cancer Center 100 participants Est. completion 2026-12-31 2 sitesOther conditions: Neuroendocrine Tumors, Progression, Neuroendocrine Tumor Grade 1, Neuroendocrine Tumor Grade 2, Neuroendocrine Tumor of Pancreas, Neuroendocrine Tumor of the Lung, Neuroendocrine Tumor CarcinoidView official trial listing → -
Recruiting NCT NCT06482086
Efficacy of Organoid-Based Drug Screening to Guide Treatment for Locally Advanced Thyroid Cancer
Not yet reported West China Hospital 75 participants Est. completion 2025-12-01 1 siteOther conditions: Locally Advanced Thyroid Gland CarcinomaView official trial listing → -
Recruiting NCT NCT06528301
A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies
Not yet reported Umoja Biopharma 106 participants Est. completion 2029-03 8 sitesOther conditions: Lymphoma, B-Cell, Lymphoma, Non-Hodgkin (NHL), Lymphoma, Large B-Cell, Diffuse (DLBCL), Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Recruiting NCT NCT06551662
DCB vs. DES in Bifurcation Coronary Lesions
Not yet reported Fondazione Ricerca e Innovazione Cardiovascolare ETS 321 participants Est. completion 2028-02-01 17 sites Stand-aloneCardiovascular disease Other conditions: DCBView official trial listing → -
Recruiting NCT NCT06552169
REgulatory T Cell Therapy to Achieve Immunosuppression REduction
Not yet reported Singulera Therapeutics Inc. 34 participants Est. completion 2031-12 7 sites Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Recruiting NCT NCT06618248
Efficacy and Safety of Sirolimus-Coated Spiral Balloon for Coronary Bifurcation Lesions
Not yet reported Dongguan TT Medical 280 participants Est. completion 2027-03 1 site Stand-aloneOther conditions: Coronary Bifurcation LesionView official trial listing → -
Recruiting NCT NCT06658093
RESTOR: PK/PD mTORi Inhibition in Older Adults
Not yet reported The University of Texas Health Science Center at San Antonio 194 participants Est. completion 2028-07 1 siteOther conditions: AgingView official trial listing → -
Recruiting NCT NCT06663696
CRUZ Tunisia-Multivessel Registry
Sahajanand Medical Technologies Limited 1000 participants Est. completion 2028-05 2 sitesOther conditions: Patient Population With Multivessel DiseaseView official trial listing → -
Recruiting NCT NCT06673290
Different Doses of Sirolimus for the Treatment of Cystic Lymphatic Malformations
Not yet reported, Not yet reported West China Hospital 150 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: Lymphatic MalformationView official trial listing → -
Recruiting NCT NCT06710210
Hybrid Percutaneous Coronary Intervention Combining a Bioresorbable Scaffold With Drug-coated Balloons Versus a Conventional Drug-eluting Stent-based Strategy in Patients With Long and Diffuse Coronary Artery Disease
Not yet reported University Hospital, Geneva 150 participants Est. completion 2028-04-01 4 sites Stand-aloneCardiovascular disease Other conditions: Percutaneous Coronary Intervention (PCI)View official trial listing → -
Recruiting NCT NCT06719791
Sirolomus Adjuvant Treatment of Focal Refractory Epilepsy (SATFRE)
Not yet reported Xuanwu Hospital, Beijing 15 participants Est. completion 2028-12-01 1 site Stand-aloneOther conditions: Epilepsy, Drug ResistantView official trial listing → -
Recruiting NCT NCT06722586
Sirolimus Monotherapy in the Treatment of Antiphospholipid Antibody Related Thrombocytopenia
Not yet reported Peking University First Hospital 84 participants Est. completion 2027-12 10 sites Stand-aloneOther conditions: Antiphospholipid (aPL)-Positive, ThrombocytopaeniaView official trial listing → -
Recruiting NCT NCT06727305
MTOR Inhibitors in Older Adults
Not yet reported, Not yet reported University of Texas Southwestern Medical Center 60 participants Est. completion 2027-11-13 1 siteOther conditions: AgingView official trial listing → -
Recruiting NCT NCT06743503
UB-VV400 in Combination With Rapamycin in Relapsed or Refractory B-cell Malignancies
Not yet reported Nanjing IASO Biotechnology Co., Ltd. 70 participants Est. completion 2030-07-31 2 sitesOther conditions: Large B-cell LymphomaView official trial listing → -
Recruiting NCT NCT06779630
Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Not yet reported Teleflex 150 participants Est. completion 2031-09 23 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT06799195
Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation
Not yet reported University of Nebraska 126 participants Est. completion 2031-11 1 site Stand-aloneOther conditions: Hematological Malignancies, Graft-versus-Host Disease (GVHD)View official trial listing → -
Recruiting NCT NCT06802055
Efficacy and Safety of Sirolimus With or Without Cyclosporin A in Chinese Patients With Aplastic Anemia Refractory/Intolerant to Cyclosporin A
Not yet reported Peking Union Medical College Hospital 40 participants Est. completion 2027-01 1 site Stand-aloneOther conditions: Aplastic AnaemiaView official trial listing → -
Recruiting NCT NCT06822712
Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for De Novo Coronary Bifurcation Lesions
Not yet reported BrosMed Medical Co., Ltd 250 participants Est. completion 2026-06 1 site Stand-aloneOther conditions: Coronary Arterial Disease (CAD)View official trial listing → -
Recruiting NCT NCT06832189
EVR and EPO for Liver Transplant Tolerance
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 20 participants Est. completion 2030-06-01 3 sitesOther conditions: Liver TransplantView official trial listing → -
Recruiting NCT NCT06856200
A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast Cancer
Not yet reported Fudan University 36 participants Est. completion 2026-06 1 site Stand-aloneOther conditions: Advanced HR - Positive, HER2 - Negative Breast Cancer, Resistant to (Neo)Adjuvant Endocrine TherapyView official trial listing → -
Recruiting NCT NCT06857058
Standardized Procedure for Intracranial Drug-Eluting Stenting in the Treatment of Intracranial Atherosclerotic Stenosis
Not yet reported Sino Medical Sciences Technology Inc. 300 participants Est. completion 2026-06-08 1 site Stand-aloneOther conditions: Intracranial Atherosclerotic StenosisView official trial listing → -
Recruiting NCT NCT06863155
Ultrathin Strut Sirolimus-eluting Stent With Bioabsorbable Polymer in Patients Receiving Chronic Oral Anticoagulation
Fundación EPIC 500 participants Est. completion 2029-03-31 13 sitesCardiovascular disease Other conditions: Ischemic Heart DiseaseView official trial listing → -
Recruiting NCT NCT06866756
Experience in Percutaneous Coronary Intervention With Sirolimus Drug-Coated Balloon and Paclitaxel Drug-Coated Balloon
Andres Iñiguez Romo 479 participants Est. completion 2026-12-31 1 siteOther conditions: Coronary Arterial Disease (CAD)View official trial listing → -
Recruiting NCT NCT06872333
Allo HSCT for High Risk Hemoglobinopathies
Not yet reported Masonic Cancer Center, University of Minnesota 62 participants Est. completion 2032-06-01 1 site Stand-aloneOther conditions: Graft Failure, Sickle Cell Disease, HemoglobinopathiesView official trial listing → -
Recruiting NCT NCT06881927
Eduction in ImmunoSuppressive Regimen Among Kidney Transplant Recipients Patients Admitted to the Intensive Care Unit for Septic Shock and/or Acute Respiratory Failure
Not yet reported University Hospital, Strasbourg, France 212 participants Est. completion 2029-08-01 1 siteOther conditions: Sepsis and Septic Shock, Acute Respiratory Failure, Kidney Transplant Recipients, Immunosuppressive AgentsView official trial listing → -
Recruiting NCT NCT06943755
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Not yet reported, Not yet reported Exelixis 440 participants Est. completion 2029-06-30 131 sitesOther conditions: Pancreatic Neuroendocrine Tumor (pNET), Extra-Pancreatic Neuroendocrine Tumor (epNET)View official trial listing → -
Recruiting NCT NCT06950385
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
Not yet reported Rapamycin Holdings Inc. 168 participants Est. completion 2031-01 29 sitesOther conditions: Familial Adenomatous Polyposis (FAP)View official trial listing → -
Recruiting NCT NCT06955169
Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior Treatment
Not yet reported RTOG Foundation, Inc. 130 participants Est. completion 2030-08 16 sitesOther conditions: Intracranial MeningiomaView official trial listing → -
Recruiting NCT NCT06959771
Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient Study
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 1 participants Est. completion 2027-10-28 1 site Stand-aloneOther conditions: CD40L-HyperIgM SyndromeView official trial listing → -
Recruiting NCT NCT06960928
Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19
Not yet reported Icahn School of Medicine at Mount Sinai 80 participants Est. completion 2027-05-31 1 site Stand-aloneOther conditions: Long COVID-19View official trial listing → -
Recruiting NCT NCT06973668
A Randomized Study to Compare Post-transplant Cyclophosphamide, Sirolimus, Ruxolitinib and Post-transplant Cyclophosphamide, Sirolimus, Mycophenolate Mofetil to Prevent Graft Versus Host Disease
Not yet reported M.D. Anderson Cancer Center 80 participants Est. completion 2030-01-31 1 site Stand-aloneOther conditions: AMLView official trial listing → -
Recruiting NCT NCT07002177
A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC
Not yet reported, Not yet reported Forward Pharmaceuticals Co., Ltd. 196 participants Est. completion 2028-11-01 1 siteOther conditions: Metastatic Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II, Locally Advanced Breast Cancer (LABC), ER+ Breast CancerView official trial listing → -
Recruiting NCT NCT07004569
Angiolite Registry Study
Chinese University of Hong Kong 55 participants Est. completion 2025-07-28 1 siteOther conditions: With Left Main Coronary Artery LesionsView official trial listing → -
Recruiting NCT NCT07015684
131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)
Not yet reported Columbia University 24 participants Est. completion 2032-03-12 1 site Stand-aloneOther conditions: Sickling Disorder Due to Hemoglobin SView official trial listing → -
Recruiting NCT NCT07022587
Bioresorbable Sirolimus-eluting scaffold in de Novo Coronary Artery Lesions
Not yet reported Xijing Hospital 2000 participants Est. completion 2073-12-20 1 site Stand-aloneCardiovascular disease Other conditions: De Novo StenosisView official trial listing → -
Recruiting NCT NCT07024173
A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer
Not yet reported Shandong Suncadia Medicine Co., Ltd. 240 participants Est. completion 2027-12 2 sitesOther conditions: Locally Advanced Breast Cancer, Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT07033858
Evaluaion the Short Term Effects of Advograf Plus Rapamiune After Kidney Transplantation
Not yet reported Shahid Beheshti University of Medical Sciences 50 participants Est. completion 2026-07-01 1 siteOther conditions: Kidney Transplant; ComplicationsView official trial listing → -
Recruiting NCT NCT07037238
An Open-Label, Single-Arm Exploratory Clinical Study of Everolimus for the Treatment of Vascular Malformations
Not yet reported Xuanwu Hospital, Beijing 10 participants Est. completion 2026-12-31 1 siteOther conditions: Vascular MalformationsView official trial listing → -
Recruiting NCT NCT07045194
Virtue® SAB in the Treatment of Coronary ISR Trial
Not yet reported Orchestra BioMed, Inc 740 participants Est. completion 2032-10 15 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT07052929
Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators
Not yet reported, Not yet reported Astellas Gene Therapies 9 participants Est. completion 2027-10-31 5 sites Stand-aloneOther conditions: X-Linked Myotubular MyopathyView official trial listing → -
Recruiting NCT NCT07062965
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
Not yet reported Pfizer 400 participants Est. completion 2030-11-04 202 sitesOther conditions: Breast CancerView official trial listing → -
Recruiting NCT NCT07077486
Effects of Telitacicept vs Cyclophosphamide on Lupus Related Interstitial Lung Disease
Not yet reported Tongji Hospital 100 participants Est. completion 2027-03-25 1 site Stand-aloneOther conditions: Lupus or SLE, Interstitial Lung Disease, Systemic Lupus ErythematosusView official trial listing → -
Recruiting NCT NCT07091682
Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold System in the Treatment of Subjects With Long de Novo Lesions
Not yet reported Biotronik AG 100 participants Est. completion 2031-06 14 sites Stand-aloneCardiovascular disease Other conditions: Atherosclerosis of Coronary Artery, Myocardial Ischemia, Ischemic Heart Disease, Acute Coronary Syndromes, Angina PectorisView official trial listing → -
Recruiting NCT NCT07092618
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation
Not yet reported, Not yet reported AgelessRx 150 participants Est. completion 2025-08 1 siteOther conditions: Longevity, GLP-1, Geroscience, AgingView official trial listing → -
Recruiting NCT NCT07095933
The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy
Not yet reported Xuanwu Hospital, Beijing 5 participants Est. completion 2026-12-31 1 siteOther conditions: Epilepsy, Drug ResistantView official trial listing → -
Recruiting NCT NCT07104331
SARC046: A Phase II Trial of Nab-Sirolimus in Patients With Progressing or Symptomatic Epithelioid Hemangioendothelioma
Not yet reported Sarcoma Alliance for Research through Collaboration 41 participants Est. completion 2029-08-30 6 sites Stand-aloneOther conditions: Epithelioid Hemangioendothelioma (EHE)View official trial listing → -
Recruiting NCT NCT07122167
Post-market Registry Study on the Safety and Efficacy of ZENFLEX Pro™ Peripheral Drug-eluting Stent System for Femoropopliteal Artery Lesions
Not yet reported MDCECRO LLC 153 participants Est. completion 2027-02-01 1 siteOther conditions: Peripheral Arterial DiseaseView official trial listing → -
Recruiting NCT NCT07124078
A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
Not yet reported Incyte Corporation 60 participants Est. completion 2029-07-31 41 sitesOther conditions: Chronic Graft-versus-host-diseaseView official trial listing → -
Recruiting NCT NCT07131644
Sirolimus Discontinuation Strategies in Kaposiform Hemangioendothelioma
Not yet reported West China Hospital 120 participants Est. completion 2028-02-01 1 site Stand-aloneOther conditions: Kaposiform HemangioendotheliomaView official trial listing → -
Recruiting NCT NCT07144150
EVERO Drug-coated Balloon (DCB) Randomized Trial
Not yet reported Cook Research Incorporated 410 participants Est. completion 2032-10 11 sitesOther conditions: Peripheral Vascular Disease, Peripheral Arterial DiseaseView official trial listing → -
Recruiting NCT NCT07162038
Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation
Not yet reported National Cancer Institute (NCI) 155 participants Est. completion 2034-10-01 1 site Stand-aloneOther conditions: Hematologic Malignancies, Hematologic NeoplasmsView official trial listing → -
Recruiting NCT NCT07165886
Sirolimus for Injection (Albumin Bound) Combined With Octreotide Long-acting Injection in Patients With Metastatic Gastroenteropancreatic Neuroendocrine Tumors
Not yet reported, Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 298 participants Est. completion 2028-08-29 1 site Stand-aloneOther conditions: Gastroenteropancreatic Neuroendocrine TumorsView official trial listing → -
Recruiting NCT NCT07173114
New Approaches for Evaluating the Interchangeability of Reference Materials and Quality Controls (COMET-MPL)
University Hospital, Montpellier 300 participants Est. completion 2026-09-22 2 sitesOther conditions: Hospitalization, All ConditionsView official trial listing → -
Recruiting NCT NCT07190690
Comparison of a Contemporary Sirolimus-eluting Stent (ihtDEStiny®) With Another Everolimus-eluting Stent (Xience™), Both With Permanent Polymers, in Patients With Acute Coronary Syndrome and de Novo Coronary Artery Lesions
Not yet reported Fundación EPIC 2100 participants Est. completion 2030-10-15 20 sitesCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT07191353
Resistance Training and Rapamycin to Enhance Bone Formation in Postmenopausal Women
Not yet reported Odense University Hospital 148 participants Est. completion 2027-03-01 2 sitesOther conditions: Healthy, Osteopenia, Osteoporosis RiskView official trial listing → -
Recruiting NCT NCT07241936
A Study of Sirolimus (Albumin-Bound) in Combination With Different ADCs Treatment of Advanced Solid Tumors
Not yet reported, Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 444 participants Est. completion 2028-10-30 1 site Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT07252050
Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease
Not yet reported, Not yet reported Arkansas Children's Hospital Research Institute 24 participants Est. completion 2029-11-19 4 sites Stand-aloneOther conditions: Sickle Cell Disease, Hematopoetic Stem Cell Transplant, Haploidentical Hematopoietic Stem Cell Transplant, Haploidentical Stem Cell Transplantation, Graft FailureView official trial listing → -
Recruiting NCT NCT07256249
Real-life Registry in Patients With Coronary Artery Disease Treated With the SELUTION Sirolimus-eluting Balloon. Selution Iberia Registry
Fundación EPIC 960 participants Est. completion 2027-01-01 14 sitesCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT07258290
Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions
Not yet reported Teleflex 1859 participants Est. completion 2033-06 3 sites Stand-aloneCardiovascular disease Other conditions: Coronary Disease, Heart Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases, Chest Pain, Pain, Neurologic Manifestations, Signs and Symptoms, Pathological Conditions, Signs and Symptoms, Myocardial Ischemia, Acute Coronary Syndrome, Angina PectorisView official trial listing → -
Recruiting NCT NCT07270549
Gene Replacement Therapy for Treatment of Paediatric Patients With CTNNB1 Neurodevelopmental Syndrome
Not yet reported, Not yet reported CTNNB1 Foundation 12 participants Est. completion 2032-12-31 1 site Stand-aloneOther conditions: CTNNB1 Neurodevelopmental SyndromeView official trial listing → -
Recruiting NCT NCT07318324
Phase Ib Study of Avutometinib, Defactinib, and Everolimus in RAS Pathway Mutant Endometrial Cancer
Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2030-08-01 1 siteOther conditions: Phase IB, Avutometinib, RAS Pathway, EndometrialView official trial listing → -
Recruiting NCT NCT07340541
Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
Not yet reported UNC Lineberger Comprehensive Cancer Center 700 participants Est. completion 2031-06-02 6 sitesOther conditions: Breast Cancer, Metastatic Breast Cancer, Triple Negative Breast Cancer, Estrogen-receptor-positive Breast Cancer, Hormone Receptor Negative Breast CarcinomaView official trial listing → -
Recruiting NCT NCT07352852
Rapamycin-Eluting Vertebral Stents In The Real-World Treatment of Symptomatic Intracranial Atherosclerotic Stenosis
The Affiliated Hospital of Qingdao University 300 participants Est. completion 2028-12-31 1 siteOther conditions: Intracranial Arterial Stenosis, Brain DiseasesView official trial listing → -
Recruiting NCT NCT07363161
BASel Kosten-Effektivitäts-Trial: Drug-coated BALLoon (DCB) vs. Drug-eluting Stent (DES) Strategy in High-risk Patients With Coronary Artery Disease (CAD)
Not yet reported B. Braun Melsungen AG 2184 participants Est. completion 2031-03 3 sitesCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT07366801
Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic Malignancies
Not yet reported, Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 64 participants Est. completion 2028-02-03 1 siteOther conditions: Acute Myeloid Leukemia, Relapsed, Acute Lymphoblastic Leukemia, High Risk, Acute Myeloid Leukemia, High Risk, Acute Lymphoblastic Leukemia, RelapseView official trial listing → -
Recruiting NCT NCT07369505
Sapu003 in Advanced mTOR-sensitive Solid Tumors
Not yet reported SAPU NANO (US) LLC 27 participants Est. completion 2026-12 1 siteOther conditions: Breast Cancer Metastatic, Renal Cell Carcinoma (RCC), Neuroendocrine Tumors, Tuberous Sclerosis Complex (TSC), Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT07378657
Systematic Approach for Children With Orbital Malformation With Sirolimus Use
Not yet reported Ain Shams University 30 participants Est. completion 2027-11-01 1 siteOther conditions: Orbital Lymphatic MalformationView official trial listing → -
Recruiting NCT NCT07426484
Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy
Not yet reported Dana-Farber Cancer Institute 80 participants Est. completion 2032-12-15 2 sites Stand-aloneOther conditions: Cutaneous Squamous Cell Carcinoma, Skin CancerView official trial listing → -
Recruiting NCT NCT07443826
CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy
Not yet reported, Not yet reported Unlimited Biotechnology LLC 12 participants Est. completion 2028-06-30 1 siteOther conditions: Age-related Muscle DeclineView official trial listing → -
Recruiting NCT NCT07444957
Safety and Effectiveness of the Crystalline Sirolimus-Eluting Device in Patients With Coronary Artery Disease
Fundación Interhospitalaria para la Investigación Cardiovascular FIC 1118 participants Est. completion 2030-07-06 1 siteCardiovascular disease Other conditions: Coronary Arterial Disease (CAD), Stable Angina, Unstable Angina, NSTEMI, Drug Coated Balloon, Silent IschemiaView official trial listing → -
Recruiting NCT NCT07463664
Clinical Outcomes of Drug-Coated Balloons in the Treatment of Patients With Coronary De Novo Chronic Total Occlusion Lesions
Not yet reported The First Affiliated Hospital of Zhengzhou University 200 participants Est. completion 2026-12-31 18 sites Stand-aloneCardiovascular disease Other conditions: Chronic Total Occlusions of Coronary Arteries, Chronic Total Occlusion (CTO)View official trial listing → -
Recruiting NCT NCT07542938
Medeliver Intracranial Drug Coated Balloon Catheter for Symptomatic Intracranial Atherosclerotic Stenosis
Not yet reported Xuanwu Hospital, Beijing 264 participants Est. completion 2027-11-30 15 sites Stand-aloneOther conditions: Symptomatic Intracranial Atherosclerotic StenosisView official trial listing → -
Recruiting NCT NCT07552077
A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Angiokeratomas (LOTU)
Not yet reported Palvella Therapeutics, Inc. 15 participants Est. completion 2027-09 4 sitesOther conditions: AngiokeratomasView official trial listing → -
Recruiting NCT NCT07582172
Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome
Not yet reported City of Hope Medical Center 35 participants Est. completion 2029-04-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia With Complex Karyotype, Myelodysplastic Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Chronic Myelomonocytic Leukemia, Recurrent Myelodysplastic Syndrome, Recurrent Secondary Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic Chronic Myelomonocytic Leukemia, Refractory Myelodysplastic Syndrome, Refractory Secondary Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07587099
Single vs. Dual Antiplatelet Therapy in Patients Undergoing Percutaneous Intervention With DCB-only Strategy (KONG-FREEDOM-I)
Not yet reported Gan Lijun 2170 participants Est. completion 2030-12-31 14 sitesOther conditions: Coronary Heart Disease (CHD)View official trial listing → -
Recruiting NCT NCT07616154
Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease
Not yet reported St. Jude Children's Research Hospital 45 participants Est. completion 2035-09 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Recruiting NCT NCT07646171
EVERST- Everolimus After Alpelisib in Women With Hormone Receptor-positive (HR+) Metastatic Breast Cancer (MBC)
Tel-Aviv Sourasky Medical Center 19 participants Est. completion 2027-12-31 1 siteOther conditions: Hormone Receptor Positive Breast CancerView official trial listing → -
Recruiting NCT NCT07656909
Low- vs High-Dose Sirolimus With Prednisolone for KHE and KMP
Not yet reported, Not yet reported Yi Ji 76 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Kaposiform Hemangioendothelioma (KHE), Kasabach Merritt PhenomenonView official trial listing → -
Recruiting NCT NCT07657793
Sirolimus in Patients With Systemic Lupus Erythematosus-Associated Immune Thrombocytopenia
Not yet reported, Not yet reported Chinese SLE Treatment And Research Group 164 participants Est. completion 2029-09-30 1 site Stand-aloneOther conditions: Systemic Lupus Erythematosus, Immune ThrombocytopeniaView official trial listing → -
Recruiting NCT NCT07725380
Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma
Not yet reported, Not yet reported H. Lee Moffitt Cancer Center and Research Institute 74 participants Est. completion 2031-08 4 sites Stand-aloneObstructive sleep apnea Other conditions: SarcomaView official trial listing → -
Recruiting NCT NCT07806370
A Single-Center, Retrospective, Propensity-Score-Matched Cohort Study Comparing Drug-Coated Balloon Versus Drug-Eluting Stent for Reducing Immediate Post-Procedural Slow-Flow/No-Reflow in Acute ST-Elevation Myocardial Infarction Patients With High Thrombus Burden
Xijing Hospital 668 participants Est. completion 2028-01-31 1 siteCardiovascular disease Other conditions: Acute Coronary Syndromes (ACS)View official trial listing → -
Recruiting NCT NCT07811024
First-in-Human Study Using the SiroMax™ Sirolimus-Coated Balloon Catheter as a Percutaneous Transluminal Coronary Angioplasty (PTCA) Balloon Catheter to Treat Subjects Who Have Coronary Artery Disease (CAD) Involving In-Stent Restenosis (ISR) or an Unstented Lesion in a Small Coronary Vessel (DNSV).
Not yet reported Tonic Medical, Inc. 60 participants Est. completion 2032-05 2 sites Stand-aloneCardiovascular disease Other conditions: In-Stent Restenosis or De Novo Coronary Artery Lesions, In-Stent Stenosis (Restenosis) of Coronary Artery Stent, Small Vessel Disease, CAD, CAD Patients, PTCA, PCI, Stenosis Coronary, Stenosis Artery, Stenotic Coronary LesionView official trial listing → -
Recruiting NCT NCT07844694
Low-Dose Sirolimus for the Treatment of RUNX1 Familial Platelet Disorder
Not yet reported OHSU Knight Cancer Institute 6 participants Est. completion 2030-12-31 1 site Stand-aloneOther conditions: Familial Platelet Disorder With Associated Myeloid MalignancyView official trial listing → -
Completed NCT NCT00001247
Inpatient Evaluation of Adults With Schizophrenia
National Institute of Mental Health (NIMH) 648 participants 1 siteOther conditions: SchizophreniaView official trial listing → -
Withdrawn NCT NCT00002790
Prevention of Graft-Versus-Host Disease in Patients With Hematologic Malignancies Who Are Receiving a Bone Marrow Transplant
Not yet reported, Not yet reported Fred Hutchinson Cancer CenterOther conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00003712
CCI-779 in Treating Patients With Advanced Solid Tumors
Not yet reported The University of Texas Health Science Center at San Antonio 15 participants Est. completion 2002-06 2 sitesOther conditions: Brain and Central Nervous System Tumors, Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Terminated NCT NCT00005113
A Study to Compare Treatment With Sirolimus Versus Standard Treatment in Patients Who Have Received a Kidney Transplant
Not yet reported Boston Children's Hospital 102 participants Est. completion 2006-03 1 site Stand-aloneOther conditions: End-Stage Renal Disease, Kidney TransplantationView official trial listing → -
Completed NCT NCT00006178
Sirolimus and Thymoglobulin to Prevent Kidney Transplant Rejection
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 12 participants Est. completion 2007-12 1 site Stand-aloneOther conditions: Kidney FailureView official trial listing → -
Completed NCT NCT00012142
CCI-779 in Treating Patients With Prostate Cancer
Not yet reported Jonsson Comprehensive Cancer Center Est. completion 2004-03 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00014911
Islet Transplantation for Type 1 Diabetes
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 36 participants Est. completion 2010-08 9 sites Stand-aloneOther conditions: Diabetes Mellitus, Insulin-DependentView official trial listing → -
Completed NCT NCT00016328
CCI-779 in Treating Patients With Recurrent Glioblastoma Multiforme
Not yet reported National Cancer Institute (NCI) 33 participants 1 siteObstructive sleep apnea Other conditions: Adult Giant Cell Glioblastoma, Adult Glioblastoma, Recurrent Adult Brain TumorView official trial listing → -
Completed NCT NCT00022464
CCI-779 in Treating Patients With Metastatic Melanoma
Not yet reported City of Hope Medical Center Est. completion 2005-09 21 sitesOther conditions: Melanoma (Skin)View official trial listing → -
Completed NCT NCT00022724
CCI-779 in Treating Patients With Malignant Glioma
Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 49 participants Est. completion 2007-12-15 10 sitesOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00023231
Pediatric Kidney Transplant Without Calcineurin Inhibitors
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 35 participants Est. completion 2006-08 1 site Stand-aloneOther conditions: End-Stage Renal DiseaseView official trial listing → -
Terminated NCT NCT00023244
Steroid Withdrawal in Pediatric Kidney Transplant Recipients
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 274 participants Est. completion 2005-06 19 sites Stand-aloneOther conditions: End-Stage Renal DiseaseView official trial listing → -
Completed NCT NCT00028028
CCI-779 in Treating Patients With Extensive-Stage Small Cell Lung Cancer
Not yet reported National Cancer Institute (NCI) 80 participants 1 siteOther conditions: Extensive Stage Small Cell Lung CancerView official trial listing → -
Completed NCT NCT00033267
CCI-779 in Treating Patients With Mantle Cell Non-Hodgkin's Lymphoma
Not yet reported National Cancer Institute (NCI) 27 participants Est. completion 2008-02 1 siteOther conditions: Recurrent Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT00037531
Study Evaluating Sirolimus (Rapamune™) in Solid Organ Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 769 participants Est. completion 2004-08 20 sitesOther conditions: Graft vs Host Disease, Kidney TransplantationView official trial listing → -
Completed NCT NCT00038948
Study Comparing Conversion to Sirolimus vs. Continued Use of Calcineurin Inhibitors in Kidney Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 830 participants Est. completion 2008-05Other conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00040508
Sirolimus for Focal Segmental Glomerulosclerosis
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 30 participants Est. completion 2005-01 1 siteOther conditions: Focal GlomerulosclerosisView official trial listing → -
Completed NCT NCT00043979
Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas
Not yet reported National Cancer Institute (NCI) 60 participants Est. completion 2011-12-14 1 site Stand-aloneOther conditions: SarcomaView official trial listing → -
Completed NCT NCT00044720
Study Evaluating Sirolimus in End Stage Renal Disease in High Risk Kidney Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 484 participants Est. completion 2005-07Other conditions: Chronic Kidney Failure, Graft vs Host Disease, Kidney TransplantationView official trial listing → -
Completed NCT NCT00045370
Chemotherapy and Biological Therapy in Treating Patients With Locally Advanced or Metastatic Kidney Cancer
Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2003-11 1 siteOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00047073
Sirolimus in Treating Patients With Glioblastoma Multiforme
Not yet reported, Not yet reported Jonsson Comprehensive Cancer Center 13 participants Est. completion 2007-10 1 siteOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00050713
Sirolimus Therapy for Idiopathic and Lupus Membranous Nephropathy
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 12 participants Est. completion 2007-08-27 1 siteOther conditions: Membranous Glomerulonephritis, Lupus Membranous NepropathyView official trial listing → -
Completed NCT NCT00060632
Safety Study of Ridaforolimus in Patients With Advanced, Refractory or Recurrent Malignancies (MK-8669-001 AM5)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 46 participants Est. completion 2005-10Other conditions: Tumors, Lymphoma, Multiple MyelomaView official trial listing → -
Completed NCT NCT00060645
Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 33 participants Est. completion 2009-02 1 siteOther conditions: Tumors, Lymphoma, Multiple MyelomaView official trial listing → -
Completed NCT NCT00061360
Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 77 participants Est. completion 2015-09-08 1 siteOther conditions: Severe Aplastic AnemiaView official trial listing → -
Active, not recruiting NCT NCT00061568
Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias
Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 130 participants Est. completion 2028-01-20 1 site Stand-aloneOther conditions: Congenital Hemolytic Anemia, Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT00062712
Evaluating the Use of Thymoglobulin, Sirolimus, and Donor Bone Marrow With Kidney Transplantation Patients
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 20 participants Est. completion 2007-03-22 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00062751
Study Evaluating Temsirolimus (CCI-779) In Breast Neoplasms
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 108 participants Est. completion 2009-10Other conditions: Breast NeoplasmsView official trial listing → -
Completed NCT NCT00065468
Study Evaluating Interferon And CCI-779 In Advanced Renal Cell Carcinoma
Not yet reported Pfizer 626 participants Est. completion 2011-03 153 sitesOther conditions: Carcinoma, Renal Cell, Kidney NeoplasmsView official trial listing → -
Completed NCT NCT00071968
Neoadjuvant CCI-779 Followed By Radical Prostatectomy in Treating Patients With Newly Diagnosed Prostate Cancer Who Have a High Risk of Relapse
Not yet reported Jonsson Comprehensive Cancer Center 15 participants 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00072176
Temsirolimus in Treating Patients With Metastatic or Locally Advanced Recurrent Endometrial Cancer
Not yet reported National Cancer Institute (NCI) 62 participants Est. completion 2009-08 1 siteOther conditions: Endometrial Adenocarcinoma, Endometrial Adenosquamous Cell Carcinoma, Endometrial Clear Cell Carcinoma, Endometrial Papillary Serous Carcinoma, Recurrent Endometrial Carcinoma, Stage IIIA Endometrial Carcinoma, Stage IIIB Endometrial Carcinoma, Stage IIIC Endometrial Carcinoma, Stage IVA Endometrial Carcinoma, Stage IVB Endometrial CarcinomaView official trial listing → -
Terminated NCT NCT00074490
Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers
Not yet reported National Cancer Institute (NCI) 442 participants Est. completion 2017-08-16 2 sites Stand-aloneOther conditions: Lymphoma, Leukemia, Myeloproliferative Disorders, Multiple Myleoma, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00075647
CCI-779 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer
Not yet reported National Cancer Institute (NCI) 40 participants 1 siteOther conditions: Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage II Pancreatic Cancer, Stage III Pancreatic Cancer, Stage IV Pancreatic CancerView official trial listing → -
Terminated NCT NCT00076206
Study Evaluating CCI-779 in Active Rheumatoid Arthritis on Concomitant Methotrexate Therapy
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer Est. completion 2005-08Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00076570
Combination Drug Therapy Followed by Single Drug Steroid Free Therapy to Prevent Organ Rejection in Kidney Transplantation
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 31 participants Est. completion 2012-08 1 site Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00078559
Combination Immunosuppressive Therapy to Prevent Kidney Transplant Rejection in Adults
Not yet reported, Not yet reported University of Wisconsin, Madison 10 participants Est. completion 2010-02 1 site Stand-aloneOther conditions: Kidney Transplantation, Kidney DiseaseView official trial listing → -
Completed NCT NCT00078689
Daclizumab and Sirolimus to Treat Uveitis
Not yet reported National Eye Institute (NEI) 6 participants Est. completion 2008-07-18 1 siteOther conditions: UveitisView official trial listing → -
Completed NCT NCT00079183
Sirolimus as Secondary Therapy in Chronic Graft-Versus-Host Disease Not Responding To Prior Treatment
Not yet reported Fred Hutchinson Cancer Center 44 participants Est. completion 2010-06-10 1 site Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT00079235
CCI-779 in Treating Patients With Stage IIIB (With Pleural Effusion) or Stage IV Non-Small Cell Lung Cancer
Not yet reported National Cancer Institute (NCI) 50 participants 1 siteOther conditions: Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT00079456
Temsirolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported National Cancer Institute (NCI) 25 participants 2 sitesOther conditions: Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple MyelomaView official trial listing → -
Completed NCT NCT00081874
RAD001 in Relapsed or Refractory AML, ALL, CML in Blastic-Phase, Agnogenic Myeloid Metaplasia, CLL, T-Cell Leukemia, or Mantle Cell Lymphoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 29 participants Est. completion 2006-09 1 siteOther conditions: Leukemia, Mantle Cell Lymphoma, MyelofibrosisView official trial listing → -
Terminated NCT NCT00083993
Study Evaluating CCI-779 and Letrozole in Post-menopausal Women With Breast Cancer
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 1236 participants Est. completion 2006-10 129 sitesOther conditions: Breast Neoplasms, Neoplasm MetastasisView official trial listing → -
Completed NCT NCT00084916
CCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, or Chronic Myelogenous Leukemia in Blastic Phase
Not yet reported National Cancer Institute (NCI) 74 participants 1 siteOther conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Blastic Phase Chronic Myelogenous Leukemia, Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Excess Blasts in Transformation, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00085566
Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate Cancer
Not yet reported, Not yet reported Memorial Sloan Kettering Cancer Center 61 participants Est. completion 2008-02 2 sitesOther conditions: Brain and Central Nervous System Tumors, Prostate CancerView official trial listing → -
Completed NCT NCT00086125
Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 57 participants Est. completion 2006-06 8 sitesOther conditions: Hematologic Malignancies, Leukemia, Myelodysplastic Syndromes, Myeloid Metaplasia, LymphomaView official trial listing → -
Terminated NCT NCT00086346
Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 607 participants Est. completion 2008-07 42 sitesOther conditions: Liver TransplantationView official trial listing → -
Terminated NCT NCT00086840
CCI-779 in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
Not yet reported National Cancer Institute (NCI) 60 participants 1 siteOther conditions: Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Refractory Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00087074
CCI-779 in Treating Patients With Soft Tissue Sarcoma or Gastrointestinal Stromal Tumor
Not yet reported National Cancer Institute (NCI) 55 participants 1 siteOther conditions: Gastrointestinal Stromal Tumor, Recurrent Adult Soft Tissue Sarcoma, Stage I Adult Soft Tissue Sarcoma, Stage II Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue SarcomaView official trial listing → -
Completed NCT NCT00087685
RAD001 in Recurrent Endometrial Cancer Patients
Not yet reported M.D. Anderson Cancer Center 35 participants Est. completion 2015-01 1 siteOther conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT00089037
Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation
Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2005-04 1 siteOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Active, not recruiting NCT NCT00092222
Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity
Not yet reported National Cancer Institute (NCI) 75 participants Est. completion 2026-10-01 1 siteOther conditions: Lymphoproliferative Disorder, HHV-8, Malignancy, HIVView official trial listing → -
Completed NCT NCT00093080
Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 216 participants Est. completion 2008-11Obstructive sleep apnea Other conditions: Sarcoma, Soft Tissue, MetastasesView official trial listing → -
Completed NCT NCT00093639
Everolimus and Imatinib Mesylate in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Who Are Not in Complete Cytogenetic Remission After Previous Imatinib Mesylate
Not yet reported, Not yet reported Novartis Pharmaceuticals Est. completion 2006-08 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00093782
Temsirolimus in Treating Patients With Metastatic Neuroendocrine Carcinoma
Not yet reported National Cancer Institute (NCI) 36 participants Est. completion 2011-04 1 siteOther conditions: Metastatic Gastrointestinal Carcinoid Tumor, Pulmonary Carcinoid Tumor, Recurrent Gastrointestinal Carcinoid Tumor, Recurrent Islet Cell CarcinomaView official trial listing → -
Terminated NCT NCT00095329
Treating Multiple Sclerosis With Sirolimus, an Immune System Suppressor
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 14 participants Est. completion 2005-03 1 site Stand-aloneOther conditions: Multiple Sclerosis (MS) - Relapsing-remittingView official trial listing → -
Completed NCT NCT00097968
Safety/Efficacy of Everolimus and Neoral® in Adult Cardiac Transplant Patients With Established Allograft Vasculopathy
Not yet reported Novartis Pharmaceuticals 6 sitesOther conditions: Graft RejectionView official trial listing → -
Completed NCT NCT00098007
A Study of Safety, Tolerability & Efficacy of Certican in de Novo Heart Transplant (Tx) Patients
Not yet reported Novartis Pharmaceuticals 199 participants Est. completion 2007-01-08 28 sitesOther conditions: Heart TransplantationView official trial listing → -
Completed NCT NCT00098241
Safety & Efficacy of Certican in Pediatric de Novo Renal Transplant Patients
Not yet reported Novartis Pharmaceuticals 45 participants Est. completion 2007-03 2 sitesOther conditions: Kidney TransplantationView official trial listing → -
Withdrawn NCT NCT00098462
Gefitinib and Sirolimus in Treating Patients With Recurrent or Refractory Stage IIIB or Stage IV Non-Small Cell Lung Cancer
Not yet reported, Not yet reported Jonsson Comprehensive Cancer CenterOther conditions: Lung CancerView official trial listing → -
Completed NCT NCT00098501
CCI-779 and EKB-569 in Treating Patients With Advanced Solid Tumors
Not yet reported National Cancer Institute (NCI) 42 participants 1 siteOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00098553
Everolimus in Treating Patients With Stage IV Melanoma
Not yet reported Alliance for Clinical Trials in Oncology 53 participants Est. completion 2010-02 94 sitesOther conditions: Melanoma (Skin)View official trial listing → -
Terminated NCT NCT00101088
Temsirolimus and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia
Not yet reported National Cancer Institute (NCI) 21 participants 1 siteOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, Blastic Phase Chronic Myelogenous Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Phase Chronic Myelogenous Leukemia, Relapsing Chronic Myelogenous LeukemiaView official trial listing → -
Completed NCT NCT00105001
Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer
Not yet reported Fred Hutchinson Cancer Center 210 participants Est. completion 2015-05-08 11 sites Stand-aloneOther conditions: Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndrome, Refractory Chronic Lymphocytic Leukemia, Refractory Plasma Cell Myeloma, Waldenstrom Macroglobulinemia, Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL, Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11, Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA, Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Lymphoma, Childhood Myelodysplastic Syndrome, Stage II Contiguous Adult Burkitt Lymphoma, Stage II Contiguous Adult Diffuse Large Cell Lymphoma, Stage II Contiguous Adult Diffuse Mixed Cell Lymphoma, Stage II Contiguous Adult Diffuse Small Cleaved Cell Lymphoma, Stage II Adult Contiguous Immunoblastic Lymphoma, Stage II Contiguous Adult Lymphoblastic Lymphoma, Stage II Grade 1 Contiguous Follicular Lymphoma, Stage II Grade 2 Contiguous Follicular Lymphoma, Stage II Grade 3 Contiguous Follicular Lymphoma, Stage II Contiguous Mantle Cell Lymphoma, Stage II Non-Contiguous Adult Burkitt Lymphoma, Stage II Non-Contiguous Adult Diffuse Large Cell Lymphoma, Stage II Non-Contiguous Adult Diffuse Mixed Cell Lymphoma, Stage II Non-Contiguous Adult Diffuse Small Cleaved Cell Lymphoma, Stage II Adult Non-Contiguous Immunoblastic Lymphoma, Stage II Non-Contiguous Adult Lymphoblastic Lymphoma, Stage II Grade 1 Non-Contiguous Follicular Lymphoma, Stage II Grade 2 Non-Contiguous Follicular Lymphoma, Stage II Grade 3 Non-Contiguous Follicular Lymphoma, Stage II Non-Contiguous Mantle Cell Lymphoma, Stage II Small Lymphocytic Lymphoma, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Burkitt Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Recurrent Childhood Hodgkin Lymphoma, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Secondary Myelodysplastic Syndrome, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Immunoblastic Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Childhood Anaplastic Large Cell Lymphoma, Stage I Childhood Large Cell Lymphoma, Stage I Childhood Lymphoblastic Lymphoma, Stage I Childhood Burkitt Lymphoma, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Small Lymphocytic Lymphoma, Stage II Childhood Anaplastic Large Cell Lymphoma, Stage II Childhood Lymphoblastic Lymphoma, Stage II Childhood Burkitt Lymphoma, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Immunoblastic Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Childhood Anaplastic Large Cell Lymphoma, Stage III Childhood Large Cell Lymphoma, Stage III Childhood Lymphoblastic Lymphoma, Stage III Childhood Burkitt Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Small Lymphocytic Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Immunoblastic Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Childhood Anaplastic Large Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma, Stage IV Childhood Lymphoblastic Lymphoma, Stage IV Childhood Burkitt Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT00106353
Study Evaluating Biomarkers In Relapsed/Refractory Pediatric Solid Tumors
Not yet reported, Not yet reported Pfizer 71 participants Est. completion 2012-01 30 sitesOther conditions: Adenocarcinoma, NeoplasmsView official trial listing → -
Completed NCT NCT00107016
Everolimus and Letrozole as Preoperative Therapy of Primary Breast Cancer in Post-menopausal Women
Not yet reported Novartis Pharmaceuticals 267 participants Est. completion 2007-04 46 sitesOther conditions: Breast NeoplasmView official trial listing → -
Completed NCT NCT00107237
AEE788 and Everolimus in Treating Patients With Recurrent or Relapsed Glioblastoma Multiforme
Not yet reported, Not yet reported Novartis Pharmaceuticals 16 participants Est. completion 2006-06 3 sitesOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00109967
CCI-779 and Rituximab in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Not yet reported National Cancer Institute (NCI) 71 participants Est. completion 2012-03 195 sitesOther conditions: Recurrent Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT00112476
Temsirolimus and Bryostatin 1 in Treating Patients With Unresectable or Metastatic Solid Tumors
Not yet reported National Cancer Institute (NCI) 24 participants 1 siteOther conditions: Recurrent Melanoma, Recurrent Renal Cell Cancer, Stage IV Melanoma, Stage IV Renal Cell Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00112736
Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma
Not yet reported, Not yet reported National Cancer Institute (NCI) 69 participants Est. completion 2014-04 8 sitesObstructive sleep apnea Other conditions: Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Adult Diffuse Astrocytoma, Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Mixed Glioma, Adult Pilocytic Astrocytoma, Adult Pineal Gland Astrocytoma, Adult Subependymal Giant Cell Astrocytoma, Recurrent Adult Brain TumorView official trial listing → -
Completed NCT NCT00112840
CCI-779 and Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 60 participants Est. completion 2015-09-10 2 sitesOther conditions: Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Cancer, Stage IV Renal Cell CancerView official trial listing → -
Completed NCT NCT00113360
RAD001 Plus Octreotide Depot in Metastatic or Unresectable Low Grade Neuroendocrine Carcinoma
Not yet reported M.D. Anderson Cancer Center 67 participants Est. completion 2009-07 1 siteOther conditions: Neuroendocrine Carcinoma, Islet Cell CarcinomaView official trial listing → -
Completed NCT NCT00117598
Study Evaluating Temsirolimus (CCI-779) In Mantle Cell Lymphoma (MCL)
Not yet reported Pfizer 169 participants Est. completion 2011-01 73 sitesOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT00117702
Prevention of the Graft-Versus-Host-Disease in Patients After Stem Cell Transplantation With Tacrolimus and Everolimus
Not yet reported, Not yet reported Technische Universität Dresden 24 participants Est. completion 2008-05 1 siteOther conditions: Graft vs Host DiseaseView official trial listing → -
Completed NCT NCT00118742
Liver Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Sirolimus in Recipients of a Liver Transplant
Not yet reported Hoffmann-La Roche 293 participants Est. completion 2008-12 46 sitesOther conditions: Liver TransplantationView official trial listing → -
Terminated NCT NCT00121784
Heart Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Heart Transplant Recipients
Not yet reported Hoffmann-La Roche 12 participants Est. completion 2006-08 29 sitesOther conditions: Heart TransplantationView official trial listing → -
Completed NCT NCT00121810
Kidney Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Kidney Transplant Recipients
Not yet reported Hoffmann-La Roche 305 participants Est. completion 2009-11 36 sites Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00122343
AP23573 in Female Adult Patients With Recurrent or Persistent Endometrial Cancer (8669-019)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 45 participants Est. completion 2008-01Other conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT00123331
Rapamycin Use in Calcineurin Inhibitor (CNI)-Free Immunosuppression for Stabilization/Improvement of Renal Function After Heart Transplantation
Not yet reported Heidelberg University 40 participants Est. completion 2005-04 1 siteOther conditions: Heart Transplantation, Renal FailureView official trial listing → -
Completed NCT NCT00124280
Study Investigating the Effect of Everolimus Monotherapy in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)
Not yet reported Novartis Pharmaceuticals 85 participants 2 sitesOther conditions: Non-small-cell Lung CarcinomaView official trial listing → -
Completed NCT NCT00126672
RAPAMYCIN FOR KIDNEY ANGIOMYOLIPOMAS
Not yet reported Dana-Farber Cancer Institute 36 participants Est. completion 2010-04 7 sitesOther conditions: Nonmalignant Neoplasm, Tuberous Sclerosis, Lymphangioleimyomatosis, Kidney AngiomyolipomaView official trial listing → -
Completed NCT NCT00129961
Study Evaluating the Effect of Sirolimus on Non-Melanoma Skin Cancer in Kidney Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 86 participants Est. completion 2009-01 23 sites Stand-aloneOther conditions: Skin Neoplasms, Kidney TransplantationView official trial listing → -
Completed NCT NCT00130546
Intra-Individual Comparison of Sirolimus and Paclitaxel Coated Stent (FRE-RACE Study)
Not yet reported University Hospital Freiburg 112 participants Est. completion 2008-07 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00133237
Drug-eluting-stents for Unprotected Left Main Stem Disease (ISAR-LEFT-MAIN)
Not yet reported Deutsches Herzzentrum Muenchen 607 participants Est. completion 2008-06 2 sitesOther conditions: Coronary DiseaseView official trial listing → -
Completed NCT NCT00133367
Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus
Not yet reported Massachusetts General Hospital 32 participants Est. completion 2011-11 2 sitesOther conditions: Multiple Myeloma, Non-Hodgkin's Lymphoma, Hodgkin's Disease, Myelogenous Leukemia, Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00133887
TUMORAPA 1: Efficacy of Rapamycin in Secondary Prevention of Skin Cancers in Kidney Transplant Recipients
Not yet reported Hospices Civils de Lyon 77 participants Est. completion 2014-05 1 siteOther conditions: Skin Cancer, Kidney TransplantationView official trial listing → -
Terminated NCT NCT00137345
Study Comparing Sirolimus With Cyclosporine in a Calcineurin Inhibitor (CNI)-Free Regimen in Kidney Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 500 participants Est. completion 2006-08 82 sitesOther conditions: Kidney TransplantView official trial listing → -
Completed NCT NCT00139386
Candesartan for Prevention of Cardiovascular Events After Cypher or Taxus Coronary Stenting (4C) Trial
Not yet reported Kumamoto University 1119 participants Est. completion 2012-04 1 siteCardiovascular disease Other conditions: HypertensionView official trial listing → -
Completed NCT NCT00140530
Nonpolymer- and Polymer-Based Drug-Eluting Stents for Restenosis (ISAR-TEST-1)
Not yet reported Deutsches Herzzentrum Muenchen 450 participants Est. completion 2005-06 2 sitesOther conditions: Coronary DiseaseView official trial listing → -
Completed NCT NCT00140543
European Trial of Immunosuppression in SPK Tx
Not yet reported EUROSPK Study Group 228 participants Est. completion 2005-09-30 14 sitesChronic kidney disease Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT00141804
Efficacy and Safety of Sirolimus in Combination With Tacrolimus
Not yet reported University Hospital Muenster 190 participants Est. completion 2005-06 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00144677
Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation
Not yet reported Dana-Farber Cancer Institute 30 participants Est. completion 2006-06 1 siteOther conditions: Acute Myelogenous Leukemia, Graft Versus Host Disease, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndromes, Non-Hodgkin's Lymphoma, Hodgkin's DiseaseView official trial listing → -
Completed NCT NCT00144703
Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Related Stem Cell Transplantation
Not yet reported Dana-Farber Cancer Institute 55 participants Est. completion 2006-11 1 siteOther conditions: Hematologic Malignancies, Myelogenous Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, Non-Hodgkin's Lymphoma, Hodgkin's DiseaseView official trial listing → -
Completed NCT NCT00146575
Sirolimus- and Paclitaxel-Eluting Stents for Small Vessels (ISAR-SMART-3)
Not yet reported Deutsches Herzzentrum Muenchen 360 participants Est. completion 2005-02 2 sites Stand-aloneOther conditions: Coronary DiseaseView official trial listing → -
Completed NCT NCT00146614
Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation
Not yet reported Dana-Farber Cancer Institute 105 participants Est. completion 2003-04 3 sitesOther conditions: Graft Versus Host Disease, Hematologic MalignanciesView official trial listing → -
No Longer Available NCT NCT00149981
A Facilitated Access Program to Provide Everolimus (RAD) Maintenance for Patients Completing Therapy in RAD Trials in Solid Organ Transplantation
Novartis Pharmaceuticals 153 sitesOther conditions: Organ TransplantationView official trial listing → -
Completed NCT NCT00150046
Efficacy and Safety of Everolimus in de Novo Heart Transplant Recipients
Not yet reported Novartis Pharmaceuticals 176 participants 2 sitesOther conditions: Heart TransplantationView official trial listing → -
Completed NCT NCT00151658
Sirolimus Eluting Stents in Complex Coronary Lesions (SCANDSTENT)
Not yet reported Copenhagen University Hospital, Rigshospitalet 322 participants Est. completion 2006-06 1 siteOther conditions: Ischaemic Heart DiseaseView official trial listing → -
Completed NCT NCT00154284
Everolimus in a Cyclosporine Microemulsion-free Regimen Compared to a Low-dose Cyclosporine Microemulsion Regimen, in de Novo Kidney Transplant Patients
Not yet reported Novartis 114 participants Est. completion 2008-07Other conditions: Organ Transplantation, Renal TransplantationView official trial listing → -
Completed NCT NCT00154297
Efficacy and Safety of Early Versus Delayed Administration of Everolimus in de Novo Renal Transplant Patients
Not yet reported Novartis Pharmaceuticals 139 participants 1 siteOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00154310
Efficacy and Safety of Everolimus With Enteric-Coated Mycophenolate Sodium (EC-MPS) in a Cyclosporine Microemulsion-free Regimen Compared to Standard Therapy in de Novo Renal Transplant Patients
Not yet reported Novartis 300 participants Est. completion 2008-09 3 sitesOther conditions: Renal TransplantationView official trial listing → -
Active, not recruiting NCT NCT00160732
Allogenic Islet Cell Transplantation
Not yet reported, Not yet reported University of Chicago 50 participants Est. completion 2030-10 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Terminated NCT NCT00166712
A Trial of Two Steroid-Free Approaches Toward Mycophenolate Mofetil-Based Monotherapy Immunosuppression
Not yet reported Northwestern University 40 participants Est. completion 2010-04 1 siteOther conditions: Kidney Transplant Failure and RejectionView official trial listing → -
Status unknown NCT NCT00166816
The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients
Not yet reported National Taiwan University Hospital 40 participants Est. completion 2003-06 1 siteOther conditions: Transplantation, Kidney Transplantation, ImmunosuppressionView official trial listing → -
Status unknown NCT NCT00166829
The Effect of Sirolimus on the Pharmacokinetics of Tacrolimus
Not yet reported National Taiwan University Hospital 40 participants 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Status unknown NCT NCT00166842
Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets
Not yet reported National Taiwan University Hospital 40 participants 1 siteOther conditions: Transplantation, Kidney Transplantation, ImmunosuppressionView official trial listing → -
Completed NCT NCT00167947
Study Evaluating Sirolimus in Kidney Transplant Recipients.
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 150 participants Est. completion 2007-07 14 sites Stand-aloneOther conditions: Kidney Failure, Graft vs Host DiseaseView official trial listing → -
Completed NCT NCT00170053
Comparison of Sirolimus to Tacrolimus for Long Term Therapy in Kidney Transplant With no Steroids
Not yet reported Mayo Clinic 177 participants Est. completion 2008-09 1 siteOther conditions: Kidney DiseasesView official trial listing → -
Completed NCT NCT00170794
Renal Safety of Everolimus in Addition to Cyclosporine Microemulsion in Cardiac Transplant Recipients.
Not yet reported Novartis PharmaceuticalsOther conditions: Cardiac TransplantationView official trial listing → -
Completed NCT NCT00170820
Efficacy and Safety of the Switch From Sirolimus to Everolimus in Stable Maintenance Renal Transplant Patients Receiving a Calcineurin Inhibitor Free Regimen
Not yet reported Novartis Pharmaceuticals 20 participants 1 siteOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00170833
Safety, Tolerability and Efficacy of Everolimus With Lower Versus Higher Levels of Tacrolimus in de Novo Renal Transplant Patients
Not yet reported Novartis Pharmaceuticals 80 participantsOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00170846
ASCERTAIN: Assessment of Everolimus in Addition to Calcineurin Inhibitor Reduction in the Maintenance of Renal Transplant Recipients
Not yet reported Novartis Pharmaceuticals 394 participants Est. completion 2009-10 1 siteOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00170859
Everolimus Versus Mycophenolate Mofetil in Combination With Reduced Dose Cyclosporine Microemulsion in Maintenance Heart Transplant Recipients
Not yet reported Novartis Pharmaceuticals Est. completion 2006-12 1 siteOther conditions: Heart TransplantationView official trial listing → -
Completed NCT NCT00170885
Everolimus in Combination With Cyclosporine Microemulsion in de Novo Renal Transplant Recipients
Not yet reported Novartis Est. completion 2007-07 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00183248
Using Donor Stem Cells and Alemtuzumab to Prevent Organ Rejection in Kidney Transplant Patients
Not yet reported, Not yet reported University of Miami 9 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: Kidney Transplantation, Kidney Disease, Kidney FailureView official trial listing → -
Completed NCT NCT00186667
Sirolimus as Primary Therapy for the Treatment of Chronic Graft Versus Host Disease
Not yet reported Stanford University 30 participants Est. completion 2005-09 1 siteOther conditions: Graft vs Host Disease, Blood and Marrow Transplant (BMT)View official trial listing → -
Completed NCT NCT00187174
Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumors
Not yet reported St. Jude Children's Research Hospital 41 participants Est. completion 2008-10 1 siteObstructive sleep apnea Other conditions: Tumors, Brain Tumors, Sarcoma, Soft TissueView official trial listing → -
Completed NCT NCT00188955
Pilot Study on the Use of Sirolimus to Treat Chronic Allograft Nephropathy in Children After Kidney Transplant
Not yet reported University of Manitoba 40 participants Est. completion 2008-10 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00189202
Efficacy of Sirolimus-Based, Steroid Avoidance Immunosuppression African Americans
Not yet reported, Not yet reported University of Michigan 49 participants Est. completion 2008-07-01 1 site Stand-aloneOther conditions: End Stage Renal Disease, Kidney TransplantationView official trial listing → -
Completed NCT NCT00195195
Study Evaluating Rapamune in Transplant Recipients in the Nordic Countries
Wyeth is now a wholly owned subsidiary of Pfizer 66 participants Est. completion 2008-06 3 sitesOther conditions: TransplantationView official trial listing → -
Completed NCT NCT00195273
Study Evaluating Sirolimus in Kidney Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 61 participants Est. completion 2008-07 3 sites Stand-aloneOther conditions: Graft vs Host Disease, Kidney TransplantationView official trial listing → -
Completed NCT NCT00195299
Study Evaluating Temsirolimus in Advanced Stage Squamous Cell Carcinoma of the Head & Neck
Wyeth is now a wholly owned subsidiary of Pfizer 20 participants Est. completion 2007-02 1 siteOther conditions: Squamous Cell CarcinomaView official trial listing → -
Completed NCT NCT00195429
A Study Comparing the Withdrawal of Steroids or Tacrolimus in Kidney Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 47 participants Est. completion 2007-10 1 site Stand-aloneOther conditions: Kidney Failure, Graft vs Host DiseaseView official trial listing → -
Completed NCT NCT00195468
Study Comparing Cyclosporine Dose Reduction vs. Cyclosporine Elimination in Kidney Transplant Recipients Taking Sirolimus
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 280 participants Est. completion 2006-11 13 sitesOther conditions: Kidney Failure, Graft vs Host DiseaseView official trial listing → -
Completed NCT NCT00195481
Study Evaluating Sirolimus in Kidney Transplant Recipients in India
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 100 participants Est. completion 2005-12 5 sitesOther conditions: Kidney Failure, Graft vs Host DiseaseView official trial listing → -
Completed NCT NCT00204321
Influence of Sirolimus and MMF on Vascular Function and Markers of Cellular Function in Renal Transplant Recipients
Not yet reported University Hospital Muenster 80 participants Est. completion 2010-01 1 siteOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00217256
The Medtronic Endeavor III Drug Eluting Coronary Stent System Clinical Trial
Not yet reported Medtronic Vascular 436 participants Est. completion 2010-12Cardiovascular diseaseView official trial listing → -
Status unknown NCT NCT00220558
GISSOC II: Sirolimus Eluting Stent Versus Bare Metal Stent in Chronic Total Coronary Occlusions
Not yet reported Società Italiana di Cardiologia Invasiva 150 participants Est. completion 2010-02 14 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00223028
Investigation of the Steady State Pharmacokinetics of Sirolimus, Mycophenolat Mofetil and Fluvastatin After Renal Transplantation
Not yet reported University Hospital Schleswig-Holstein 15 participants Est. completion 2005-07Other conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00223054
Polymorphism of the Cytochrome P450-system in Renal Transplants
University Hospital Schleswig-Holstein 200 participants Est. completion 2006-10 1 siteOther conditions: Function of Renal TransplantView official trial listing → -
Completed NCT NCT00223678
Mycophenolate Mofetil and Rapamycin as Secondary Intervention vs. Continuation of Calcineurin Inhibitors in Patients at Risk for Chronic Renal Allograft Failure
Not yet reported Vanderbilt University Medical Center 20 participants Est. completion 2009-10 1 siteOther conditions: Kidney TransplantView official trial listing → -
Completed NCT NCT00228397
Study Evaluating CCI-779 in Relapsing Multiple Sclerosis
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 221 participants Est. completion 2005-11Other conditions: Multiple Sclerosis, Relapsing-RemittingView official trial listing → -
Status unknown NCT NCT00229515
Multicentre 2x2 Factorial Randomised Study Comparing Tirofiban Versus Abciximab and SES Versus BMS in AMI
Not yet reported Marco Valgimigli 744 participants Est. completion 2012-03 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00231244
Sirolimus-Eluting BX VELOCITYTM Balloon-Expandable Stent in a Compassionate Use Registry (SECURE)
Not yet reported Cordis US Corp. 252 participants Est. completion 2008-11 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00231257
Sirolimus-Eluting Stent vs. Intravascular Brachytherapy in In-Stent Restenotic Coronary Artery Lesions(SISR)
Not yet reported Cordis US Corp. 384 participants Est. completion 2009-09 1 site Stand-aloneOther conditions: In-Stent RestenosisView official trial listing → -
Completed NCT NCT00231283
NEXUS Study for the Treatment of de Novo Native Coronary Artery Lesions
Not yet reported Cordis US Corp. 100 participants Est. completion 2005-07 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00232739
Study of the 2.25mm Sirolimus-Eluting Stent in the Treatment of Patients With Coronary Artery Lesions
Not yet reported Cordis US Corp. 100 participants Est. completion 2009-08 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00232752
Study of the 4.0mm Sirolimus-Eluting Stent in the Treatment of Patients With Coronary Artery Lesions
Not yet reported Cordis US Corp. 100 participants Est. completion 2009-11 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00232765
Study of Sirolimus-Coated BX VELOCITY Balloon-Expandable Stent in Treatment of de Novo Native Coronary Artery Lesions (SIRIUS)
Not yet reported Cordis US Corp. 1058 participants Est. completion 2008-11 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00232791
The Study to Compare Cypher Versus Cypher Select in Treating Cornary Artery Lesions.
Not yet reported, Not yet reported Cordis US Corp. 102 participants Est. completion 2005-03 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00232830
The Study to Assess AMI Treated With Balloon Angioplasty.
Not yet reported Cordis US Corp. 715 participants Est. completion 2009-04 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00232856
A Study of the Cypher SES to Treat Restenotic Native Coronary Artery Lesions.
Not yet reported Cordis US Corp. 162 participants Est. completion 2006-08 2 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00232869
A Study of the SMART Stent in the Treatment SFA Disease.
Not yet reported Cordis US Corp. 93 participants Est. completion 2009-05 1 site Stand-aloneOther conditions: Peripheral Artery DiseaseView official trial listing → -
Completed NCT NCT00233714
Double or Single Dose Sirolimus-Eluting Stents in Diabetic Patients With de Novo Coronary Artery Lesions
Not yet reported, Not yet reported Cordis US Corp. 56 participants Est. completion 2009-11 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00233766
Evaluation of Two Reduced Sirolimus Doses in Treatment of de Novo Coronary Artery Lesions (REDOX)
Not yet reported, Not yet reported Cordis US Corp. 60 participants Est. completion 2007-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00233779
Evaluation of Sirolimus-Eluting, Heparin-Coated CoCr Stent in the Treatment of de Novo Coronary Artery Lesions in Small Vessels(EVOLUTION)
Not yet reported Cordis US Corp. 52 participants Est. completion 2004-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00233792
FIM-BR - First-in-Man Study (Brazil Part) With Sirolimus-Coated BX VELOCITY Stent
Not yet reported, Not yet reported Cordis US Corp. 30 participants Est. completion 2005-03 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00233805
The Initial Double-Blind Drug-Eluting Stent vs Bare-Metal Stent Study.
Not yet reported Cordis US Corp. 220 participants Est. completion 2007-12 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00233818
FIM-NL - First-in-Man Study (Netherlands Part) With Sirolimus Coated Modified BX Velocity Stent
Not yet reported, Not yet reported Cordis US Corp. 15 participants Est. completion 2005-06 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00234455
A Study of the Cypher Sirolimus-Eluting Stent to Treat Bifurcation Lesions.
Not yet reported Cordis US Corp. 86 participants Est. completion 2007-04 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00235066
The CYPHER™ Stent Study in Patients With Small de Novo Coronary Artery Lesions.
Not yet reported Cordis US Corp. 100 participants Est. completion 2006-04 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00235092
The REALITY Study - Head-to-Head Comparison Between Cypher and Taxus
Not yet reported Cordis US Corp. 1335 participants Est. completion 2006-03 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00235144
The Study of the BX VELOCITY Stent In Patients With De Novo Coronary Artery Lesions.
Not yet reported Cordis US Corp. 353 participants Est. completion 2008-09 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00235157
A Comparison of Coated and Uncoated Stents in Renal Artery Treatment.
Not yet reported Cordis US Corp. 105 participants Est. completion 2005-07 3 sites Stand-aloneOther conditions: Renal Artery StenosisView official trial listing → -
Completed NCT NCT00235170
The Arterial Revascularization Therapies Study Part II.
Not yet reported Cordis US Corp. 607 participants Est. completion 2009-04 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00235560
Rapamycin in Combination With Low-dose Aracytin in Elderly Acute Myeloid Leukemia Patients
Not yet reported University Hospital, Toulouse 50 participants Est. completion 2008-06 3 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00235794
An Open Label Exploratory Study in Newly Diagnosed Prostate Cancer Patients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 50 participants Est. completion 2007-09 1 siteOther conditions: Prostatic NeoplasmsView official trial listing → -
Terminated NCT NCT00240214
Study Evaluating Rapamune in Patients After Kidney Transplantation
Wyeth is now a wholly owned subsidiary of Pfizer 500 participants Est. completion 2008-02 1 siteOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00240994
Safety in Immunomodulatory Functions of Alemtuzumab (Campath) in Pediatric Kidney Transplantation Recipients
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 35 participants Est. completion 2009-11 4 sites Stand-aloneOther conditions: Kidney Failure, Chronic, Kidney Transplantation, ImmunosuppressionView official trial listing → -
Completed NCT NCT00241189
Rapamycin vs Methotrexate in Diffuse SSc
Not yet reported, Not yet reported University of California, Los Angeles 17 participants Est. completion 2006-06 1 siteOther conditions: Systemic SclerosisView official trial listing → -
Completed NCT NCT00245401
CYPHERTM Stent Post-Marketing Surveillance Registry (US-PMS)
Not yet reported Cordis US Corp. 2070 participants Est. completion 2004-12Cardiovascular diseaseView official trial listing → -
Completed NCT NCT00248313
Study Comparing Cyclosporin Dose Reduction With Cyclosporin Elimination in Kidney Transplant Recipients Taking Sirolimus
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 470 participants Est. completion 2007-10Other conditions: Kidney DiseaseView official trial listing → -
Status unknown NCT NCT00252655
Use of Sirolimus vs. Tacrolimus For African-American Renal Transplant Recipients
Not yet reported Wayne State University 40 participants Est. completion 2009-06 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Terminated NCT NCT00253318
RAD001 Plus Docetaxel in Patients With Metastatic Breast Cancer
Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2012-04 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00254709
Study Evaluating Two Different Sirolimus-based Immunosuppressive Regimens in Elderly Kidney Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 66 participants Est. completion 2005-09Other conditions: Kidney Failure, Graft Rejection, AgedView official trial listing → -
Completed NCT NCT00255658
Sorafenib and Temsirolimus in Treating Patients With Unresectable or Metastatic Solid Tumors
Not yet reported National Cancer Institute (NCI) 40 participants Est. completion 2007-04 1 siteOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00255788
Everolimus in Treating Patients WIth Recurrent or Metastatic Breast Cancer
Not yet reported NCIC Clinical Trials Group 49 participants Est. completion 2011-01-18 5 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00257387
Study Evaluating Cyclosporine Dose Reduction and Cyclosporine Elimination in Chinese Kidney Transplants
Not yet reported, Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 120 participants Est. completion 2006-08Other conditions: Kidney TransplantView official trial listing → -
Completed NCT NCT00258596
Sirolimus-Eluting Stents for Chronic Total Coronary Occlusions
Not yet reported R&D Cardiologie 200 participants Est. completion 2006-09 2 sitesCardiovascular disease Other conditions: Coronary Disease, Coronary StenosisView official trial listing → -
Completed NCT NCT00261820
Study Comparing Two Immunosuppressive Regimens in De Novo Renal Allograft Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 160 participants Est. completion 2005-01Other conditions: Graft Rejection, Kidney Failure, Kidney TransplantationView official trial listing → -
Completed NCT NCT00263263
RRISC Study: Reduction of Restenosis In Saphenous Vein Grafts With Cypher Sirolimus-Eluting Stent.
Not yet reported Antwerp Cardiovascular Institute Middelheim 75 participants Est. completion 2005-12 1 siteCardiovascular disease Other conditions: Stable Angina, Unstable Angina, Saphenous Vein Graft DiseaseView official trial listing → -
Completed NCT NCT00265473
MGA031, Sirolimus and Tacrolimus in Islet Transplantation
Not yet reported, Not yet reported University of Minnesota 5 participants Est. completion 2010-06 1 siteOther conditions: Type 1 Diabetes Mellitus, HypoglycemiaView official trial listing → -
Completed NCT NCT00267189
RESCUE Study - Everolimus in Liver Transplantation Recipients With Renal Insufficiency
Not yet reported Novartis Pharmaceuticals 145 participants Est. completion 2007-11 2 sitesOther conditions: Liver TransplantationView official trial listing → -
Completed NCT NCT00273871
Study Comparing Conversion From Calcineurin Inhibitors to Rapamune Versus Standard Therapy in Established Renal Allograft Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 190 participants Est. completion 2006-09Other conditions: Graft Rejection, Kidney Failure, Kidney TransplantationView official trial listing → -
Completed NCT NCT00275093
Temsirolimus in Treating Patients With Metastatic Solid Tumor or Lymphoma That Cannot Be Removed By Surgery Who Have Different Levels of Liver Function
Not yet reported National Cancer Institute (NCI) 130 participants 1 siteOther conditions: Hepatic Complications, Lymphoma, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00275522
The Comparison of Three Different Immunosuppressant Regimens in Kidney Transplant Recipients.
Not yet reported Mayo Clinic 16 participants Est. completion 2007-12 1 siteOther conditions: Kidney TransplantView official trial listing → -
Completed NCT NCT00275535
The Comparison of Tacrolimus and Sirolimus Immunosuppression Based Drug Regimens in Kidney Transplant Recipients
Not yet reported Mayo Clinic 165 participants Est. completion 2008-12 1 siteOther conditions: Kidney DiseasesView official trial listing → -
Completed NCT NCT00276575
Bevacizumab, Everolimus, and Erlotinib in Treating Patients With Advanced Solid Tumors
Not yet reported Herbert Hurwitz, MD 65 participants Est. completion 2014-09 1 siteOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Terminated NCT NCT00276744
Individualized Drug Treatment for Treating Patients With Pancreatic Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 249 participants Est. completion 2010-04 1 siteOther conditions: Pancreatic CancerView official trial listing → -
Completed NCT NCT00281957
Sorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By Surgery
Not yet reported National Cancer Institute (NCI) 109 participants Est. completion 2011-01 173 sitesOther conditions: Recurrent Melanoma, Stage IV MelanomaView official trial listing → -
Completed NCT NCT00282217
Study Evaluating Sirolimus in the Treatment of Kidney Transplant
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 100 participants 13 sitesOther conditions: Kidney Failure, Kidney DiseasesView official trial listing → -
Completed NCT NCT00282282
Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-myeloablative Peripheral Blood Stem Cell Transplantation
Not yet reported Dana-Farber Cancer Institute 31 participants Est. completion 2009-07 1 siteOther conditions: Graft Versus Host Disease, GVHDView official trial listing → -
Completed NCT NCT00285194
hOKT3γ1 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients
Not yet reported, Not yet reported University of Minnesota 6 participants Est. completion 2004-01 1 siteOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Completed NCT NCT00285233
Delayed Mycophenolate Mofetil in Single-Donor Islet Allotransplantation in Type 1 Diabetes
Not yet reported, Not yet reported University of Minnesota 8 participants Est. completion 2005-03 1 siteOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Completed NCT NCT00286156
Pilot Study of Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Not yet reported, Not yet reported The Cleveland Clinic 30 participants Est. completion 2014-12 1 siteOther conditions: Polycystic Kidney DiseasesView official trial listing → -
Completed NCT NCT00286624
Anti-Thymocyte Globulin, Cyclosporine, and RAD in Islet Transplantation
Not yet reported, Not yet reported University of Minnesota 6 participants Est. completion 2006-08 1 siteOther conditions: Type 1 Diabetes Mellitus, HypoglycemiaView official trial listing → -
Status unknown NCT NCT00288210
Sirolimus Eluting Stenting in Acute Myocardial Infarction
Not yet reported San Camillo Hospital, Rome Est. completion 2006-03 1 siteCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT00288535
Treatment of Bifurcated Coronary Lesions With Cypher™-Stent
Not yet reported University Heart Center Freiburg - Bad Krozingen 200 participants Est. completion 2007-02 1 siteCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT00290069
Renal Function Optimization With Mycophenolate Mofetil (MMF) Immunosuppressor Regimes (ALHAMBRA)
Not yet reported Sociedad Andaluza de Trasplantes de Organos y Tejidos 94 participants 7 sitesOther conditions: Kidney Diseases, Graft RejectionView official trial listing → -
Completed NCT NCT00290472
CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
Not yet reported National Cancer Institute (NCI) 89 participants Est. completion 2010-04 13 sitesObstructive sleep apnea Other conditions: B-cell Chronic Lymphocytic Leukemia, Malignant Neoplasm, Nodal Marginal Zone B-cell Lymphoma, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Splenic Marginal Zone Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00296361
To Compare the Efficacy and Safety of a Therapy of Tacrolimus With Sirolimus or MMF in Kidney Transplantation.
Not yet reported Astellas Pharma Inc 634 participants Est. completion 2006-07 59 sitesOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00297661
Sirolimus-Eluting Versus Paclitaxel-Eluting Stents for Coronary Revascularization
Not yet reported University of Bern 1012 participants 1 siteOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00300274
Efficacy and Safety of Everolimus in Recipients of Heart Transplants to Prevent Acute and Chronic Rejection
Not yet reported Novartis Pharmaceuticals 721 participants Est. completion 2011-07 64 sitesOther conditions: Graft RejectionView official trial listing → -
Completed NCT NCT00303732
Vatalanib and Everolimus in Treating Patients With Advanced Solid Tumors
Not yet reported Daniel George, MD 37 participants Est. completion 2012-08 1 siteOther conditions: Kidney Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00304954
Infliximab, Sirolimus and Daclizumab to Treat Age-Related Macular Degeneration
Not yet reported National Eye Institute (NEI) 13 participants Est. completion 2010-01 1 siteOther conditions: Age-Related Macular Degeneration, Choroidal NeovascularizationView official trial listing → -
Completed NCT NCT00305396
Calcineurin Inhibitor Avoidance With Thymoglobulin and Sirolimus in Kidney Transplantation
Not yet reported Vanderbilt University 80 participants Est. completion 2005-03 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00305682
Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant
Not yet reported Masonic Cancer Center, University of Minnesota 295 participants Est. completion 2019-12-12 1 siteOther conditions: Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00306397
Pilot Study to Investigate a Steroid Free Immunosuppressive Regimen for Renal Transplant Recipients
Not yet reported University Hospital, Basel, Switzerland 100 participants Est. completion 2008-12 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Withdrawn NCT NCT00309231
Clinical Islet Transplantation Using the Edmonton Protocol
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Est. completion 2008-01 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00309270
Low Dose Sirolimus or CsA-Based Maintenance Immunosuppression After Induction With Campath-1 in Kidney Transplantation
Not yet reported Mario Negri Institute for Pharmacological Research 21 participants Est. completion 2010-04 1 siteOther conditions: Kidney TransplantView official trial listing → -
Terminated NCT NCT00311311
Study Comparing Effect On Carotid Atherosclerosis Following Conversion From Tacrolimus To Sirolimus Post-Transplant In Kidney Transplant Patients
Not yet reported Pfizer 72 participants Est. completion 2012-01 8 sites Stand-aloneOther conditions: Atherosclerosis, Kidney FailureView official trial listing → -
Completed NCT NCT00311623
Sirolimus Before Surgery in Treating Patients With Advanced Localized Prostate Cancer
Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 32 participants Est. completion 2010-06 3 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00316849
Temsirolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Not yet reported National Cancer Institute (NCI) 56 participants 11 sitesObstructive sleep apnea Other conditions: Adult Giant Cell Glioblastoma, Adult GlioblastomaView official trial listing → -
Completed NCT NCT00317785
Total-Body Irradiation and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer and Other Diseases
Not yet reported Fred Hutchinson Cancer Center 50 participants 2 sitesOther conditions: Leukemia, Lymphoma, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00317798
Antithymocyte Globulin and Sirolimus in Treating Patients With Relapsed Multiple Myeloma
Not yet reported University of Rochester 18 participants Est. completion 2011-04 1 siteOther conditions: Drug/Agent Toxicity by Tissue/Organ, Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Status unknown NCT NCT00319878
Sirolimus and Cyclosporine for Treatment-Resistant Aplastic Anemia
Not yet reported, Not yet reported Office of Rare Diseases (ORD) 52 participants Est. completion 2009-12 4 sites Stand-aloneOther conditions: Anemia, AplasticView official trial listing → -
Completed NCT NCT00321906
Comparison of Sirolimus and Azathioprine in Lung Transplantation
Not yet reported University of Chicago 181 participants Est. completion 2011-08 1 siteOther conditions: Delayed Graft Function, Acute Graft RejectionView official trial listing → -
Completed NCT NCT00323739
Bevacizumab (Avastin) and RAD001(Everolimus)in the Treatment of Advanced Clear Cell Renal Carcinoma
Not yet reported SCRI Development Innovations, LLC 80 participants Est. completion 2011-03 12 sitesOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00323895
The Intra-Drug Eluting Stent (DES) Restenosis Study
Not yet reported Cordis US Corp. 320 participants Est. completion 2010-01 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT00325325
Pharmacokinetic Study on the Combination of Everolimus-Tacrolimus
Not yet reported Hospital Universitario Ramon y Cajal 40 participants Est. completion 2007-06 1 siteOther conditions: Kidney DiseasesView official trial listing → -
Completed NCT NCT00328770
De Novo Sirolimus-based Immunosuppression After Liver Transplantation for Hepatocellular Carcinoma
Not yet reported, Not yet reported University of Alberta 70 participants Est. completion 2006-03 1 site Stand-aloneOther conditions: Liver CarcinomaView official trial listing → -
Completed NCT NCT00329719
Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent Glioblastoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 115 participants Est. completion 2013-02-02 190 sitesObstructive sleep apnea Other conditions: Adult Glioblastoma, Recurrent Adult Brain NeoplasmView official trial listing → -
Completed NCT NCT00331409
Everolimus and Imatinib Mesylate in Treating Patients With Metastatic or Unresectable Kidney Cancer
Not yet reported OHSU Knight Cancer Institute 23 participants Est. completion 2010-01 1 siteOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00332397
The Efficacy of Three Different Limus Agent-Eluting Stents to Prevent Restenosis
Not yet reported Deutsches Herzzentrum Muenchen 1007 participants Est. completion 2007-07 2 sitesOther conditions: Coronary DiseaseView official trial listing → -
Terminated NCT NCT00332839
Comparison of CNI-based Regimen Versus CNI-free Regimen in Kidney Transplant Recipients.
Not yet reported Novartis Pharmaceuticals 93 participants Est. completion 2013-03 11 sitesOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00335764
Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 92 participants Est. completion 2012-09 7 sitesObstructive sleep apnea Other conditions: Adult Giant Cell Glioblastoma, Adult Glioblastoma, Recurrent Adult Brain TumorView official trial listing → -
Terminated NCT NCT00337376
A Study of the mTOR Inhibitor Rapamycin (Rapamune, Sirolimus) in Combination With Abraxane in Advanced Solid Cancers
Not yet reported Yale University 23 participants Est. completion 2010-07 1 siteOther conditions: Advanced Solid CancersView official trial listing → -
Completed NCT NCT00337545
Phase II Trial of RAD001 in Refractory Colorectal Cancer
Not yet reported Swedish Medical Center 22 participants Est. completion 2007-04 1 siteOther conditions: Colorectal CancerView official trial listing → -
Terminated NCT NCT00346151
Belatacept to Prevent Organ Rejection in Kidney Transplant Patients
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 5 participants Est. completion 2010-02 2 sites Stand-aloneOther conditions: Renal TransplantView official trial listing → -
Completed NCT NCT00346918
Sirolimus (Rapamune®) for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Not yet reported University of Zurich 100 participants Est. completion 2010-06 1 siteOther conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)View official trial listing → -
Completed NCT NCT00349206
Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma
Not yet reported National Cancer Institute (NCI) 69 participants Est. completion 2012-02 1 siteOther conditions: Melanoma, Recurrent Melanoma, Stage III Melanoma, Stage IV MelanomaView official trial listing → -
Completed NCT NCT00350181
Sirolimus & Mycophenolate Mofetil as GVHD Prophylaxis in Myeloablative, Matched Related Donor HCT
Not yet reported Stanford University 11 participants Est. completion 2010-04 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Non-Hodgkin, Hematologic Diseases, Acute GVHDView official trial listing → -
Completed NCT NCT00350454
Rapamycin-Eluting Stents With Different Polymer Coating to Reduce Restenosis (ISAR-TEST-3)
Not yet reported Deutsches Herzzentrum Muenchen 605 participants Est. completion 2007-10 2 sitesOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00352092
Pilot Study for HLA Identical Living Donor Renal Transplant Recipients
Not yet reported University of Cincinnati 20 participants Est. completion 2007-12 1 siteOther conditions: Renal TransplantView official trial listing → -
Completed NCT NCT00352443
S0528 Lapatinib and Everolimus in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma
Not yet reported SWOG Cancer Research Network 66 participants Est. completion 2013-09 6 sitesOther conditions: Lymphoma, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00352547
Influence of Genes on Sirolimus Metabolism in Patients With Kidney Transplantation
National Institutes of Health Clinical Center (CC) 93 participants Est. completion 2013-12-02 1 siteOther conditions: Renal TransplantView official trial listing → -
Withdrawn NCT NCT00352950
Safety Evaluation of Panitumumab and Sirolimus in Advanced Non-Small Cell Lung Cancer
Not yet reported Amgen Est. completion 2008-02Other conditions: Oncology, Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT00352976
TBI Dose De-escalation for Fanconi Anemia
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 83 participants Est. completion 2020-10-09 1 site Stand-aloneOther conditions: Fanconi AnemiaView official trial listing → -
Completed NCT NCT00353301
Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma
Not yet reported University of Colorado, Denver 25 participants Est. completion 2012-03 1 site Stand-aloneOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00355862
Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma
Not yet reported University of Regensburg 525 participants Est. completion 2014-05 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT00358657
Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerous Inherited Disorders
Not yet reported Fred Hutchinson Cancer Center 14 participants Est. completion 2019-05-25 3 sites Stand-aloneOther conditions: Immunodeficiency Syndrome, Severe Aplastic Anemia, Genetic DisorderView official trial listing → -
Completed NCT NCT00363051
Safety/Efficacy of Everolimus in Adults With Advanced Pancreatic Neuroendocrine Cancer Not Responsive to Chemotherapy
Not yet reported Novartis Pharmaceuticals 160 participants Est. completion 2012-04 54 sitesOther conditions: Islet Cell Carcinoma, Neuroendocrine Carcinoma, Neuroendocrine Tumor, Pancreatic NeoplasmsView official trial listing → -
Completed NCT NCT00365846
"A Pilot Study to Determine the Safety of Campath-1H (Anti-CD52) Therapy in Primary Renal Allograft Transplantation"
Not yet reported University of Wisconsin, Madison 29 participants Est. completion 2006-07 1 site Stand-aloneOther conditions: Renal TransplantView official trial listing → -
Completed NCT NCT00368914
Sirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 30 participants Est. completion 2009-06 1 siteOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00369161
A Twelve-month, Multicenter, Open-label, Randomized Study of the Safety, Tolerability and Efficacy of Everolimus With Basiliximab, Corticosteroids and Two Different Exposure Levels of Tacrolimus in de Novo Renal Transplant Recipients
Not yet reported Novartis 228 participants Est. completion 2008-12 1 siteOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00369382
Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 121 participants Est. completion 2010-05 23 sites Stand-aloneOther conditions: Graft Rejection, Kidney FailureView official trial listing → -
Terminated NCT NCT00373815
Everolimus in Combination With Cyclosporine A and Prednisolone for the Treatment of Graft Versus Host Disease
Not yet reported University Hospital Tuebingen 10 participants Est. completion 2009-10 1 siteOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT00374140
Phase II Trial of RAD001 (Everolimus) in Previously Treated Small Cell Lung Cancer
Not yet reported Ahmad Tarhini 40 participants Est. completion 2012-06 19 sitesOther conditions: Small Cell Lung CancerView official trial listing → -
Completed NCT NCT00374647
Study to Evaluate Safety and Efficacy of Early Calcineurin Inhibitor Withdrawal in Primary Renal Allografts
Not yet reported University of Cincinnati 17 participants Est. completion 2007-12 2 sitesOther conditions: Primary Renal AllograftView official trial listing → -
Completed NCT NCT00375245
Rapamycin With Grapefruit Juice for Advanced Malignancies
Not yet reported University of Chicago 41 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: Tumors, Neoplasm MetastasisView official trial listing → -
Completed NCT NCT00376688
Temsirolimus in Treating Patients With Locally Advanced or Metastatic Breast Cancer
Not yet reported National Cancer Institute (NCI) 31 participants Est. completion 2019-12-16 2 sitesOther conditions: Recurrent Breast Carcinoma, Stage III Breast Cancer AJCC v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Stage IV Breast Cancer AJCC v6 and v7View official trial listing → -
Status unknown NCT NCT00376870
PIoglitazone for PrEvention of Restenosis in Diabetic Patients
Not yet reported University of Rome Tor Vergata 160 participants Est. completion 2011-04 2 sitesOther conditions: Coronary Atherosclerosis, Coronary Restenosis, DiabetesView official trial listing → -
Completed NCT NCT00377962
Nordic Everolimus (Certican) Trial in Heart and Lung Transplantation
Not yet reported Novartis Pharmaceuticals 282 participants Est. completion 2010-02 6 sitesOther conditions: Disorder Related to Cardiac TransplantationView official trial listing → -
Completed NCT NCT00378014
Preservation of Renal Function in Liver Transplant Recipients With Certican Therapy
Not yet reported Novartis Pharmaceuticals 276 participants Est. completion 2013-01 16 sitesOther conditions: Liver TransplantationView official trial listing → -
Completed NCT NCT00378612
ACROSS-Cypher Total Occlusion Study of Coronary Arteries 4 Trial
Not yet reported Sunil Rao 200 participants Est. completion 2012-09 16 sites Stand-aloneOther conditions: Coronary OcclusionsView official trial listing → -
Completed NCT NCT00378703
Bevacizumab, Sorafenib Tosylate, and Temsirolimus in Treating Patients With Metastatic Kidney Cancer
Not yet reported National Cancer Institute (NCI) 361 participants Est. completion 2017-03-21 559 sitesOther conditions: Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v7View official trial listing → -
Completed NCT NCT00381420
The Study of the BX Velocity Stent in the Treatment of De Novo Artery Lesions.
Not yet reported Cordis US Corp. 100 participants Est. completion 2008-06 Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00382109
Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission
Not yet reported Children's Oncology Group 146 participants Est. completion 2017-06-30 50 sites Stand-aloneOther conditions: B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Graft Versus Host Disease, L1 Childhood Acute Lymphoblastic Leukemia, L2 Childhood Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00384969
Sorafenib and RAD001 Renal Cell Carcinoma
Not yet reported University of California, San Francisco 21 participants Est. completion 2014-03 1 siteOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00387400
Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme
Not yet reported NCIC Clinical Trials Group 32 participants Est. completion 2012-01-06 9 sitesOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00389220
Limus Eluted From A Durable Versus ERodable Stent Coating
Not yet reported Biosensors Europe SA 1707 participants Est. completion 2012-06 10 sitesOther conditions: Coronary Disease, Coronary StenosisView official trial listing → -
Status unknown NCT NCT00390195
Randomized Phase I/II of RAD001 in Advanced Hepatocellular Carcinoma (HCC)
Not yet reported, Not yet reported National Health Research Institutes, Taiwan 134 participants Est. completion 2011-06 2 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT00390364
Everolimus in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Previous Therapy
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 1 participants Est. completion 2007-10 1 siteOther conditions: Colorectal CancerView official trial listing → -
Completed NCT NCT00392821
Dosing and Effectiveness Study of Sorafenib and RAD001 in the Treatment of Patients With Advanced Kidney Cancer
Not yet reported, Not yet reported SCRI Development Innovations, LLC 78 participants Est. completion 2013-10 11 sitesOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00392951
Sirolimus for Autoimmune Disease of Blood Cells
Not yet reported, Not yet reported Children's Hospital of Philadelphia 30 participants Est. completion 2016-02 1 site Stand-aloneOther conditions: Autoimmune Pancytopenia, Autoimmune Lymphoproliferative Syndrome (ALPS), Evans Syndrome, Idiopathic Thrombocytopenic Purpura, Anemia, Hemolytic, Autoimmune, Autoimmune Neutropenia, Lupus Erythematosus, Systemic, Inflammatory Bowel Disease, Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00396721
Sirolimus Therapy for Poor Prognosis Immunoglobulin A Nephropathy
Not yet reported Josep m Cruzado 23 participants Est. completion 2010-02 1 site Stand-aloneOther conditions: Glomerulonephritis, IGA, Nephropathy, IGA, IGA NephropathyView official trial listing → -
Completed NCT NCT00397982
Temsirolimus and Bevacizumab in Treating Patients With Stage III or Stage IV Malignant Melanoma
Not yet reported National Cancer Institute (NCI) 17 participants Est. completion 2013-07 2 sitesOther conditions: Recurrent Melanoma, Stage IIIB Skin Melanoma, Stage IIIC Skin Melanoma, Stage IV Skin MelanomaView official trial listing → -
Completed NCT NCT00398515
Lenalidomide and Temsirolimus in Treating Patients With Previously Treated Multiple Myeloma
Not yet reported National Cancer Institute (NCI) 25 participants 1 siteOther conditions: Refractory Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple MyelomaView official trial listing → -
Completed NCT NCT00401115
Safety and Tolerability of MS-R001 in Patients With Diabetic Macular Edema Secondary to Diabetic Retinopathy
Not yet reported Santen Inc. 50 participants Est. completion 2008-06 2 sitesOther conditions: Diabetic Macular Edema, Diabetic RetinopathyView official trial listing → -
Completed NCT NCT00401778
Trial of RAD001 in Patients With Operable Non-Small Cell Lung Cancer (NSCLC)
Not yet reported Emory University 33 participants Est. completion 2013-12 1 siteOther conditions: Lung CancerView official trial listing → -
Terminated NCT NCT00402415
Study of Combination of Sirolimus and Sutent in Patients With Advanced Solid Tumors Non-Curable With Standard Therapy
Not yet reported Yale University 18 participants Est. completion 2008-07 1 siteOther conditions: TumorsView official trial listing → -
Completed NCT NCT00402532
Immunosuppressive Therapy With Certican (Everolimus) After Lung Transplantation
Not yet reported Hannover Medical School 190 participants Est. completion 2011-12 1 siteOther conditions: Lung TransplantationView official trial listing → -
Completed NCT NCT00402636
Rapamycin+Estradiol- vs. Rapamycin-Eluting Stents to Reduce Restenosis (ISAR-PEACE)
Not yet reported Deutsches Herzzentrum Muenchen 502 participants Est. completion 2006-10 2 sitesOther conditions: Coronary Heart DiseaseView official trial listing → -
Terminated NCT NCT00402662
A Study of Everolimus in Combination With Imatinib in Metastatic Melanoma
Not yet reported Yale University 3 participants Est. completion 2006-06 1 siteOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT00403338
The Impact of Stent Deployment Techniques on Clinical Outcomes of Patient Treated With the CYPHER® Stent (S.T.L.L.R.)
Cordis US Corp. 1500 participants Est. completion 2006-04Other conditions: Coronary StenosisView official trial listing → -
Terminated NCT NCT00406276
Phase I/II Trial of RAD001 Plus Docetaxel in Patients With Metastatic or Recurrent Non-Small Cell Lung Cancer
Not yet reported, Not yet reported Emory University 28 participants Est. completion 2013-02 1 siteOther conditions: Lung CancerView official trial listing → -
Completed NCT NCT00406393
Sirolimus/Tacrolimus Versus Tacrolimus/Methotrexate for Preventing Graft-Versus-Host Disease (GVHD) (BMT CTN 0402)
Not yet reported Medical College of Wisconsin 304 participants Est. completion 2015-10 24 sites Stand-aloneOther conditions: Leukemia, Myelocytic, Acute, Leukemia, Lymphocytic, Acute, Leukemia, Myeloid, Chronic, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00408655
Temsirolimus, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Tumors
Not yet reported National Cancer Institute (NCI) 38 participants 1 siteOther conditions: Ovarian Sarcoma, Ovarian Stromal Cancer, Recurrent Endometrial Carcinoma, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Stage III Endometrial Carcinoma, Stage III Ovarian Epithelial Cancer, Stage III Ovarian Germ Cell Tumor, Stage IV Endometrial Carcinoma, Stage IV Ovarian Epithelial Cancer, Stage IV Ovarian Germ Cell Tumor, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00409292
RAD001 in Previously Treated Patients With Metastatic Pancreatic Cancer
Not yet reported Dana-Farber Cancer Institute 33 participants Est. completion 2009-05 3 sitesOther conditions: Pancreatic CancerView official trial listing → -
Terminated NCT NCT00409461
Comparison of Sirolimus Alone With Sirolimus Plus Tacrolimus in Type 1 Diabetic Recipients of Cultured Islet Cell Grafts
Not yet reported Universitair Ziekenhuis Brussel 2 sitesOther conditions: Islet Transplantation, Type 1 DiabetesView official trial listing → -
Completed NCT NCT00409994
Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer
Not yet reported, Not yet reported Maastricht Radiation Oncology 44 participants Est. completion 2018-12 1 siteOther conditions: Rectum CancerView official trial listing → -
Completed NCT NCT00410124
RAD001 Plus Best Supportive Care (BSC) Versus BSC Plus Placebo in Patients With Metastatic Carcinoma of the Kidney Which Has Progressed After Treatment With Sorafenib and/or Sunitinib
Not yet reported Novartis Pharmaceuticals 416 participants Est. completion 2011-10 93 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00411619
Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex
Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 28 participants Est. completion 2014-01 1 siteOther conditions: Tuberous Sclerosis, Subependymal Giant Cell AstrocytomaView official trial listing → -
Completed NCT NCT00411788
A Phase II Study of Rapamycin and Trastuzumab for Patients With HER-2 Receptor Positive Metastatic Breast Cancer
Not yet reported Yale University 11 participants Est. completion 2010-05 2 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00412061
Everolimus and Octreotide in Patients With Advanced Carcinoid Tumor
Not yet reported Novartis Pharmaceuticals 429 participants Est. completion 2013-06 70 sitesOther conditions: Carcinoid Tumor, Malignant Carcinoid SyndromeView official trial listing → -
Completed NCT NCT00414440
Efficacy, Safety and Tolerability of Everolimus in Preventing End-stage Renal Disease in Patients With Autosomal Dominant Polycystic Kidney Disease
Not yet reported Novartis Pharmaceuticals 431 participants Est. completion 2013-10 24 sitesOther conditions: Autosomal Dominant Polycystic Kidney DiseaseView official trial listing → -
Completed NCT NCT00414648
Efficacy and Safety of Sirolimus in LAM
Not yet reported University of Cincinnati 89 participants Est. completion 2011-02 13 sites Stand-aloneOther conditions: LymphangioleiomyomatosisView official trial listing → -
Terminated NCT NCT00417677
A Study Combining Treatment With Temsirolimus and Sunitinib for Subjects With Advanced Renal Cell Carcinoma
Not yet reported, Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 124 participants Est. completion 2007-05 4 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00418067
Zotarolimus-Eluting Stent Versus Sirolimus-Eluting Stent and PacliTaxel-Eluting Stent for Coronary Lesions
Not yet reported Seung-Jung Park 2645 participants Est. completion 2009-01 20 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00419159
Efficacy and Safety of Everolimus in Patients With Metastatic Colorectal Cancer Who Have Failed Prior Targeted Therapy and Chemotherapy
Not yet reported Novartis Pharmaceuticals 199 participants Est. completion 2009-03 1 siteOther conditions: Colorectal CancerView official trial listing → -
Terminated NCT NCT00420537
Shift to Everolimus (RAD) Kidney Sparing Study
Not yet reported University of Bologna 34 participants Est. completion 2009-03 1 siteOther conditions: Kidney Dysfunction, Heart TransplantationView official trial listing → -
Completed NCT NCT00422344
A Study of RAD001 and Sunitinib in Metastatic Renal Cell Carcinoma
Not yet reported Memorial Sloan Kettering Cancer Center 20 participants Est. completion 2010-02 1 siteOther conditions: Renal Cell Carcinoma, Kidney CancerView official trial listing → -
Terminated NCT NCT00422565
Zotarolimus-Versus Sirolimus-Versus PacliTaxel-Eluting Stent for Acute Myocardial Infarction Patients
Not yet reported Seung-Jung Park 328 participants Est. completion 2008-09 12 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00422968
Bypass Surgery Versus Angioplasty Using Sirolimus-Eluting Stent in Patients With Left Main Coronary Artery Disease
Not yet reported Seung-Jung Park 1454 participants Est. completion 2013-12 13 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00423865
Cisplatin and Everolimus in Treating Patients With Advanced Solid Tumors
Not yet reported Memorial Sloan Kettering Cancer Center 30 participants Est. completion 2011-09 1 siteOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00425308
Efficacy and Safety of Everolimus in Combination With Cyclosporine Microemulsion Versus Everolimus in Combination With Enteric-coated Mycophenolate Sodium (EC-MPS), in Adult Renal Transplant Patients in Maintenance.
Not yet reported Novartis Pharmaceuticals 30 participants 1 siteOther conditions: Renal TransplantationView official trial listing → -
Status unknown NCT NCT00426049
Systemic Treatment With Everolimus for the Prevention of MACE After Bare Metal Stent Implantation
Not yet reported German Heart Institute 484 participants 1 siteCardiovascular disease Other conditions: Coronary RestenosisView official trial listing → -
Completed NCT NCT00426517
Donor Stem Cell Transplantation for Congenital Immunodeficiencies
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 48 participants Est. completion 2019-11-01 1 site Stand-aloneOther conditions: Inherited Immune DeficienciesView official trial listing → -
Completed NCT NCT00426530
Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer
Not yet reported Novartis Pharmaceuticals 50 participants Est. completion 2010-06 6 sitesOther conditions: Breast Neoplasms, Neoplasm MetastasisView official trial listing → -
Completed NCT NCT00426556
Efficacy and Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer
Not yet reported Novartis Pharmaceuticals 88 participants Est. completion 2014-03 20 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT00428064
Study Evaluating Sirolimus and Cyclosporine in Kidney Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 408 participants Est. completion 2004-06Other conditions: Renal TransplantationView official trial listing → -
Terminated NCT NCT00429052
Mechanism of Percutaneous Revascularization for Coronary Bifurcation Disease
University of Florida 24 participants Est. completion 2008-09 1 siteOther conditions: Coronary DiseaseView official trial listing → -
Completed NCT NCT00429793
Temsirolimus in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer
Not yet reported National Cancer Institute (NCI) 60 participants Est. completion 2012-01 1 siteOther conditions: Fallopian Tube Cancer, Primary Peritoneal Cavity Cancer, Recurrent Ovarian Epithelial CancerView official trial listing → -
Completed NCT NCT00433485
Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants
Not yet reported Yale University 16 participants Est. completion 2008-03Other conditions: Neoplastic Syndrome, Non-melanomatous Skin CancerView official trial listing → -
Completed NCT NCT00434174
Safety of Everolimus and Pemetrexed in Lung Cancer Patients
Not yet reported Novartis Pharmaceuticals 48 participants Est. completion 2010-12 5 sitesOther conditions: Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT00434811
Islet Transplantation in Type 1 Diabetes
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 48 participants Est. completion 2014-05 8 sites Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00434850
Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 14 participants Est. completion 2013-11 3 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00436618
Everolimus in Treating Patients With Lymphoma That Has Relapsed or Not Responded to Previous Treatment
Not yet reported Mayo Clinic 277 participants Est. completion 2019-10-09 3 sitesOther conditions: Leukemia, Lymphoma, Lymphoproliferative DisorderView official trial listing → -
Completed NCT NCT00438919
A Multi-center Post-Market Surveillance Registry
Not yet reported Cordis US Corp. 15000 participants Est. completion 2009-12 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00443937
Pharmacokinetics of Everolimus and Enteric-Coated Mycophenolatesodium Before and After Withdrawal of Cyclosporine in Renal Transplant Patients
Not yet reported Charite University, Berlin, Germany 15 participants Est. completion 2006-03 1 siteOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00446264
Islet Allotransplantation With Steroid Free Immunosuppression
Not yet reported University Hospital, Lille 14 participants Est. completion 2009-02 1 site Stand-aloneOther conditions: Type 1 Diabetes, Hypoglycemia, Metabolic DiseasesView official trial listing → -
Completed NCT NCT00446368
Safety Study of RAD001 to Treat Patients With Metastatic Kidney Cancer
Not yet reported The Methodist Hospital Research Institute 66 participants Est. completion 2008-10 1 siteOther conditions: Carcinoma, Renal CellView official trial listing → -
Completed NCT NCT00448149
Phase I/II Trial of RAD001 Plus Nexavar in Patients With Kidney Cancer
Not yet reported, Not yet reported The Methodist Hospital Research Institute 55 participants Est. completion 2009-06 1 siteOther conditions: Carcinoma, Renal CellView official trial listing → -
Completed NCT NCT00449280
Drug Interaction Study of Sorafenib and Rapamycin in Advanced Malignancies
Not yet reported University of Chicago 34 participants Est. completion 2009-09 1 siteOther conditions: Advanced Solid TumorView official trial listing → -
Completed NCT NCT00449748
Everolimus (RAD001) as Therapy for Patients With Systemic Mastocytosis
Not yet reported M.D. Anderson Cancer Center 10 participants Est. completion 2009-10 1 siteOther conditions: Systemic MastocytosisView official trial listing → -
Completed NCT NCT00450320
Sirolimus in Treating Patients With HIV-Related Kaposi's Sarcoma
Not yet reported AIDS Malignancy Consortium 7 participants Est. completion 2009-09 3 sitesOther conditions: SarcomaView official trial listing → -
Terminated NCT NCT00452361
Study Evaluating of Calcineurin Inhibitors Versus Sirolimus in Renal Allograft Recipient
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 31 participants Est. completion 2008-08 1 site Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00452517
Comparison of Stent Graft, Sirolimus Stent, and Bare Metal Stent Implanted in Patients With Acute Coronary Syndrome
Not yet reported University of Zagreb 100 participants Est. completion 2004-11 1 siteOther conditions: Acute Coronary SyndromeView official trial listing → -
Completed NCT NCT00455013
A Phase II Study of Belatacept (BMS-224818) With a Steroid-free Regimen in Subjects Undergoing Kidney Transplantation
Not yet reported Bristol-Myers Squibb 93 participants Est. completion 2012-08 17 sites Stand-aloneOther conditions: Disorder Related to Renal TransplantationView official trial listing → -
Completed NCT NCT00456833
Combination of RAD001 and Erlotinib in Patients With Advanced Non Small Cell Lung Cancer Previously Treated Only With Chemotherapy
Not yet reported Novartis Pharmaceuticals 248 participants 14 sitesOther conditions: Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT00457119
Combination of RAD001 With Carboplatin, Paclitaxel and Bevacizumab in Non-small-cell Lung Cancer (NSCLC) Patients
Not yet reported Novartis Pharmaceuticals 69 participants Est. completion 2009-11 8 sitesOther conditions: Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT00457808
Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM
Not yet reported Children's Hospital Medical Center, Cincinnati 25 participants Est. completion 2006-03 1 siteOther conditions: Tuberous Sclerosis, LymphangioleiomyomatosisView official trial listing → -
Completed NCT NCT00457964
RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM
Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 36 participants Est. completion 2013-07 1 siteOther conditions: Tuberous Sclerosis, LymphangioleiomyomatosisView official trial listing → -
Completed NCT NCT00458237
Dose Escalation Followed by Study of RAD001 in Combination With Trastuzumab in HER2-Positive Metastatic Breast Cancer
Not yet reported, Not yet reported Beth Israel Deaconess Medical Center 11 participants Est. completion 2010-04 2 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00459186
The Use of RAD001 With Docetaxel in the Treatment of Metastatic, Androgen Independent Prostate Cancer
Not yet reported, Not yet reported Dana-Farber Cancer Institute 19 participants Est. completion 2012-12 5 sitesOther conditions: Metastatic, Androgen Independent Prostate Cancer, Prostate CancerView official trial listing → -
Status unknown NCT NCT00461357
Sirolimus Based Immunosuppression for Patients Undergoing Kidney Transplantation in the Eurotransplant Senior Program
Medical University of Vienna 48 participants Est. completion 2007-12Other conditions: Kidney Function After Transplantation, Outcome After Kidney TransplantationView official trial listing → -
Completed NCT NCT00464399
Feasibility and Safety of Early Switch to Everolimus From Cyclosporine in de Novo Renal Transplant Patients
Not yet reported Novartis Pharmaceuticals 20 participants 1 siteOther conditions: De Novo Renal TransplantationView official trial listing → -
Completed NCT NCT00464555
Strategies to Improve Islet Survival
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 5 participants Est. completion 2014-02 2 sites Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00466466
Safety of RAD001 in Combination With Cisplatin and Etoposide in Lung Cancer Patients
Not yet reported Novartis Pharmaceuticals 20 participants 6 sitesOther conditions: Small-Cell Lung CancerView official trial listing → -
Completed NCT NCT00467194
Sirolimus and Bevacizumab in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery
Not yet reported National Cancer Centre, Singapore 27 participants 2 sitesOther conditions: Liver CancerView official trial listing → -
Terminated NCT NCT00468442
B-Lymphocyte Immunotherapy in Islet Transplantation
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 2 participants Est. completion 2011-09 1 site Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00470665
Study Comparing Sirolimus/Prograf vs Sirolimus/CsA in High-Risk Renal Transplant Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 460 participants Est. completion 2004-07Other conditions: Renal Allograft RecipientsView official trial listing → -
Terminated NCT NCT00473005
Phase I Oral mTOR Inhibitor RAD001 in Combo w/ Capecitabine for Metastatic Breast
Not yet reported Stanford University 18 participants Est. completion 2011-12 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00473499
PEPCAD III Substudy: Stem Cell Mobilization
Not yet reported, Not yet reported University Hospital, Saarland 60 participants Est. completion 2009-11 1 siteCardiovascular diseaseView official trial listing → -
Terminated NCT NCT00473551
Anti-Third Party T Lymphocytes With Nonmyeloablative Stem Cell Transplantation for Indolent Lymphoid Malignancies
Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, MyelomaView official trial listing → -
Completed NCT NCT00473772
DEBlue Stent vs Cypher Stent in the Treatment of Advanced Coronary Artery Disease
Not yet reported, Not yet reported University Hospital, Saarland 643 participants Est. completion 2011-01 16 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00474786
Temsirolimus Versus Sorafenib As Second-Line Therapy In Patients With Advanced RCC Who Have Failed First-Line Sunitinib
Not yet reported Pfizer 512 participants Est. completion 2013-01 128 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00474929
Sorafenib and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma
Not yet reported, Not yet reported Mayo Clinic 103 participants Est. completion 2019-08-08 2 sitesOther conditions: Lymphoma, Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00476957
Randomized Study Comparing Endeavor With Cypher Stents (PROTECT)
Not yet reported Medtronic Vascular 8709 participants Est. completion 2014-07 1 siteOther conditions: Ischemic Heart DiseaseView official trial listing → -
Completed NCT NCT00478608
Study Evaluating Rapamune® Maintenance Regimen
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 79 participants Est. completion 2008-11 9 sitesOther conditions: Renal TransplantView official trial listing → -
Completed NCT NCT00478634
A Phase 1 Study Investigating the Combination of RAD001, Cetuximab and Irinotecan as Second-line Therapy After FOLFOX (or XELOX) Plus Bevacizumab in Patients With Metastatic Colorectal Cancer
Not yet reported Novartis Pharmaceuticals 19 participants Est. completion 2009-09 16 sitesOther conditions: Colorectal Cancer, Colorectal Carcinoma, Colorectal Tumors, Neoplasms, ColorectalView official trial listing → -
Completed NCT NCT00482183
Comparison Between Pioglitazone and SES With type2 DM
Not yet reported, Not yet reported Showa University 38 participants Est. completion 2007-06Cardiovascular diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT00483262
Combination CCI-779 (Temsirolimus) and Bortezomib (Velcade) in Relapsed and/or Relapsed/Refractory Multiple Myeloma
Not yet reported, Not yet reported Dana-Farber Cancer Institute 63 participants Est. completion 2012-02 3 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00484094
Study Investigating Rapamune For Post-Marketing Surveillance
Pfizer 209 participants Est. completion 2015-06 11 sitesOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00485004
Focal In-stent Restenosis After Drug-Eluting Stent
Not yet reported Seung-Jung Park 100 participants Est. completion 2011-03 15 sites Stand-aloneOther conditions: In Stent RestenosisView official trial listing → -
Completed NCT NCT00485030
Diffuse Type In-Stent Restenosis After Drug-Eluting Stent
Not yet reported Seung-Jung Park 60 participants Est. completion 2011-10 15 sites Stand-aloneOther conditions: In-stent RestenosisView official trial listing → -
Terminated NCT NCT00489164
Feasibility Study With the Sirolimus-Eluting BX Velocity Balloon-Expandable Stent in the Treatment of Diabetic Patients With Native Coronary Artery Lesions
Not yet reported, Not yet reported Cordis US Corp. 83 participants Est. completion 2004-05 11 sitesOther conditions: Peripheral Vascular DiseasesView official trial listing → -
Terminated NCT NCT00489281
Non-Myeloablative Bone Marrow Transplant for Patients With Sickle Cell Anemia and Other Blood Disorders
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 43 participants Est. completion 2018-12-29 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Status unknown NCT NCT00490789
Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM
Not yet reported Cardiff University 14 participants Est. completion 2009-09 3 sitesOther conditions: Tuberous Sclerosis, LymphangioleiomyomatosisView official trial listing → -
Completed NCT NCT00491517
Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety
Not yet reported Mario Negri Institute for Pharmacological Research 22 participants Est. completion 2009-08 1 site Stand-aloneOther conditions: Polycystic KidneyView official trial listing → -
Status unknown NCT NCT00493194
Fibrosis in Renal Allografts
Not yet reported University Hospital, Antwerp 100 participants Est. completion 2007-07 3 sitesOther conditions: Kidney Failure, Chronic, Transplantation, Immunosuppression, Interstitial FibrosisView official trial listing → -
Completed NCT NCT00494091
Study Evaluating The Safety, Efficacy & Pharmacokinetics Of Temsirolimus(CCI-779) In Subjects With Advanced Renal Cell Carcinoma
Not yet reported Pfizer 82 participants Est. completion 2012-03 24 sitesOther conditions: Advanced Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00495898
A Study of Diabetic Patients With De Novo Native Coronary Artery Lesions
Not yet reported Cordis US Corp. 200 participants Est. completion 2009-11 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00496600
Phase I Study of Patupilone and RAD001
Not yet reported University of Medicine and Dentistry of New Jersey 42 participants Est. completion 2011-02 1 siteOther conditions: Refractory MalignancyView official trial listing → -
Completed NCT NCT00497172
Diabetes Drug Eluting Sirolimus Stent Experience in Restenosis Trial
Not yet reported Cordis US Corp. 150 participants Est. completion 2009-04 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00498966
Ph II Study of Perifosine for Patients With Carcinoma of the Kidney
Not yet reported AEterna Zentaris 50 participants Est. completion 2011-10 3 sitesOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00499486
Sirolimus in Treating Patients With Advanced Pancreatic Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 47 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Pancreatic CancerView official trial listing → -
Status unknown NCT NCT00499603
Paclitaxel Followed by FEC Versus Paclitaxel and RAD001 Followed by FEC In Women With Breast Cancer
Not yet reported M.D. Anderson Cancer Center 62 participants Est. completion 2017-04 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00502242
Study Evaluating The Effect Of Ramipril On Urinary Protein Excretion In Renal Transplant Patients Converted To Sirolimus
Not yet reported Pfizer 229 participants Est. completion 2013-09 49 sitesOther conditions: Kidney TransplantView official trial listing → -
Status unknown NCT NCT00505102
Safe Renal Function In Long Term Heart Transplanted Patients
Not yet reported A.O. Ospedale Papa Giovanni XXIII 200 participants Est. completion 2009-07 2 sitesOther conditions: Kidney Diseases, Heart TransplantationView official trial listing → -
Terminated NCT NCT00506948
Thymoglobulin, Sirolimus and Mycophenolate Mofetil for Prevention of Acute Graft-Versus-Host Disease (GVHD)
Not yet reported M.D. Anderson Cancer Center 13 participants Est. completion 2010-10 1 site Stand-aloneOther conditions: Hematological Malignancies, Myelodysplastic Syndrome, Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00507793
Study Evaluating the Efficacy and Safety of Cyclosporine Reduction in Kidney Transplant Recipients Receiving Sirolimus
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 385 participants Est. completion 2002-06Other conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00509431
Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma
Not yet reported Jonsson Comprehensive Cancer Center 19 participants Est. completion 2012-09 1 site Stand-aloneOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00509613
Phase 1 Study With Sorafenib and Sirolimus
Not yet reported Radboud University Medical Center 1 siteOther conditions: Advanced Solid Tumor, Refractory to Standard TherapiesView official trial listing → -
Completed NCT NCT00510068
Efficacy and Safety of Everolimus (RAD001) Compared to Placebo in Patients With Advanced Neuroendocrine Tumors
Not yet reported Novartis Pharmaceuticals 410 participants Est. completion 2014-03 82 sitesOther conditions: Advanced Neuroendocrine Tumors of Pancreatic OriginView official trial listing → -
Terminated NCT NCT00512668
Hormone Therapy and Temsirolimus in Treating Patients With Relapsed Prostate Cancer
Not yet reported National Cancer Institute (NCI) 24 participants 1 siteOther conditions: Adenocarcinoma of the Prostate, Recurrent Prostate CancerView official trial listing → -
Completed NCT NCT00513474
Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant
Not yet reported Massachusetts General Hospital 46 participants Est. completion 2013-02-12 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00514514
Study Investigating a Standard Regimen in de Novo Kidney Transplant Patients Versus a Calcineurin Inhibitor (CNI)-Free Regimen and a CNI-low Dose Regimen
Not yet reported Novartis Pharmaceuticals 802 participants Est. completion 2015-06 18 sitesOther conditions: Kidney TransplantationView official trial listing → -
Terminated NCT NCT00515086
Study of Everolimus (RAD001) in Patients With Recurrent Glioblastoma Multiforme (GBM)
Not yet reported Novartis Pharmaceuticals 41 participants Est. completion 2009-08 8 sitesOther conditions: Glioblastoma MultiformeView official trial listing → -
Completed NCT NCT00516165
RAD001 in Advanced Hepatocellular Carcinoma
Not yet reported, Not yet reported Massachusetts General Hospital 28 participants Est. completion 2011-11 3 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT00518271
Study Comparing Standard Dose and Reduced Dose Tacrolimus + Sirolimus + Corticosteroids in Renal Allograft Recipients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 120 participants Est. completion 2002-06Other conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00518375
Study Comparing Graft Function in Renal Allograft Recepients Receiving Reduced or Standard Dose CsA With Sirolimus
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 250 participants Est. completion 2001-05Other conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00519116
Study Comparing Standard Dose and Reduced Dose Tacrolimus With Sirolimus in Renal Transplant Patients
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 150 participants Est. completion 2001-08Other conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00519324
Efficacy and Safety of Everolimus (RAD001) in Patients With Advanced Gastric Cancer
Not yet reported Novartis Pharmaceuticals 54 participants 8 sitesOther conditions: Advanced Gastric CancerView official trial listing → -
Completed NCT NCT00520130
Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune System
Not yet reported, Not yet reported National Cancer Institute (NCI) 92 participants Est. completion 2018-12-31 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, Hodgkin's Lymphoma, Non-Hodgkin's Disease, Acute Leukemia, Multiple MyelomaView official trial listing → -
Completed NCT NCT00521001
Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by Surgery
Not yet reported Alliance for Clinical Trials in Oncology 49 participants Est. completion 2010-12 198 sitesOther conditions: Melanoma (Skin)View official trial listing → -
Completed NCT NCT00522665
Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer
Not yet reported, Not yet reported Hoosier Cancer Research Network 41 participants Est. completion 2015-02 14 sitesOther conditions: Colorectal CancerView official trial listing → -
Completed NCT NCT00523432
A Phase I Study of CCI-779 (Temsirolimus) in Combination With Topotecan in Patients With Gynecologic Malignancies
Not yet reported University of Chicago 15 participants Est. completion 2010-12 1 siteOther conditions: Genital Neoplasms, FemaleView official trial listing → -
Completed NCT NCT00525889
Proleukin and Rapamune in Type 1 Diabetes
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 9 participants Est. completion 2013-09 3 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Terminated NCT NCT00526591
Everolimus in Treating Patients With Newly Diagnosed Localized Prostate Cancer
Not yet reported Jorge A. Garcia, MD 17 participants Est. completion 2011-08 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00529802
Exploratory Study Evaluating Fluorodeoxyglucose - Position Emission Tomography as a Predictive Marker for Therapy With RAD001 in Metastatic Renal Cell Cancer
Not yet reported University of Chicago 60 participants Est. completion 2010-07 5 sitesOther conditions: Carcinoma, Renal CellView official trial listing → -
Completed NCT NCT00531063
This is a Two-year Follow-up Study to Evaluate the Long-term Safety, Tolerability and Efficacy of 2 Different Doses of Everolimus
Not yet reported Novartis Pharmaceuticals 237 participants 1 siteOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00531440
This is a 2-year Follow-up Study to Evaluate the Long-term Effects in Patients Who Completed the Study CRAD001A2307.
Not yet reported Novartis Pharmaceuticals 256 participants 1 siteOther conditions: Renal TransplantationView official trial listing → -
Active, not recruiting NCT NCT00544115
Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders
Not yet reported City of Hope Medical Center 260 participants Est. completion 2027-03-29Other conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Precancerous/Nonmalignant ConditionView official trial listing → -
Status unknown NCT NCT00544999
Everolimus, Cytarabine, and Daunorubicin in Treating Patients With Relapsed Acute Myeloid Leukemia
Not yet reported Institut de Recherche Clinique sur les Cancers et le Sang 21 participants 1 siteOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00548717
Sirolimus, Mycophenolate Mofetil and Bortezomib as Graft-Versus-Host Disease (GVHD) Prophylaxis After Reduced Intensity Conditioning (RIC) Hematopoietic Stem Cell Transplantation
Not yet reported Dana-Farber Cancer Institute 15 participants Est. completion 2013-09 1 site Stand-aloneOther conditions: Graft-vs-Host DiseaseView official trial listing → -
Status unknown NCT NCT00552656
Long Term Efficacy and Safety of Firebird Sirolimus-Eluting Stent In Complex Coronary Lesions
Xijing Hospital 1000 participants Est. completion 2010-08 1 siteOther conditions: Coronary DiseaseView official trial listing → -
Completed NCT NCT00552669
Study of Oral Rapamycin Plus Bare Metal Stents vs Drug Eltuting Stents
Not yet reported Centro de estudios en Cardiologia Intervencionista 200 participants Est. completion 2007-09 3 sites Stand-aloneOther conditions: Coronary Heart Disease, Coronary RestenosisView official trial listing → -
Completed NCT NCT00553150
Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Not yet reported, Not yet reported Alliance for Clinical Trials in Oncology 122 participants Est. completion 2019-11-15 178 sitesOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Status unknown NCT NCT00554125
Sirolimus-Based Immunosuppression Therapy in OLT for Patients With HCC Exceeding Milan Criteria
Not yet reported Fudan University 220 participants Est. completion 2013-08 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT00555256
A Phase I Study of SUNITINIB and Rapamycin in Advanced Non-Small Cell Lung Cancer (NSCLC)
Not yet reported Washington University School of Medicine 19 participants Est. completion 2012-12 1 siteOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT00555373
Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based Immunosuppression
Not yet reported Pediatric Nephrology of Alabama 52 participants Est. completion 2012-11 4 sitesOther conditions: Renal TransplantView official trial listing → -
Completed NCT NCT00556933
Improved Induction and Maintenance Immunosuppression in Kidney Transplantation
Not yet reported University of Nebraska 180 participants Est. completion 2011-06-01 1 site Stand-aloneOther conditions: End-stage Renal DiseaseView official trial listing → -
Completed NCT NCT00560963
Treatment of Patients Suffering From a Progressive Pancreas Carcinoma With Everolimus (RAD001) and Gemcitabine
Not yet reported, Not yet reported Novartis Pharmaceuticals 21 participants Est. completion 2011-01 5 sitesOther conditions: Advanced or Metastatic Pancreatic AdenocarcinomaView official trial listing → -
Completed NCT NCT00563147
A Phase 1b, Open-Label, Dose-Finding Study to Evaluate the Safety of Tivozanib (AV-951) in Combination With Temsirolimus in Subjects With Metastatic Renal Cell Carcinoma
Not yet reported AVEO Pharmaceuticals, Inc. 28 participants Est. completion 2011-02 5 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00565773
Belatacept Post Depletional Repopulation to Facilitate Tolerance
Not yet reported Allan D Kirk, MD, PhD 40 participants Est. completion 2017-07-01 2 sites Stand-aloneOther conditions: Organ TransplantationView official trial listing → -
Completed NCT NCT00566813
Islet Transplantation in Type 1 Diabetic Patients Using the Edmonton Protocol of Steroid Free Immunosuppression
Not yet reported, Not yet reported University of Illinois at Chicago 10 participants Est. completion 2020-07-15 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00567554
Bevacizumab, Everolimus (RAD001), and Lapatinib as Neoadjuvant Chemotherapy Regimes for Primary Breast Cancer
Not yet reported GBG Forschungs GmbH 2600 participants Est. completion 2015-10 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00570921
Study of Combined Fulvestrant and Everolimus in Advanced/Metastatic Breast Cancer After Aromatase Inhibitor Failure
Not yet reported Mara Chambers 33 participants Est. completion 2015-01 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00574366
Erlotinib and Everolimus in Treating Patients With Metastatic Breast Cancer
Not yet reported Vanderbilt-Ingram Cancer Center 14 participants Est. completion 2009-02 3 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00574769
Safety Study & Effectiveness of Docetaxel With RAD001 and Bevacizumab in Men With Advanced Prostate Cancer
Not yet reported, Not yet reported University of Southern California 27 participants Est. completion 2017-02-17 2 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00576680
RAD001 and Temozolomide in Patients With Advanced Pancreatic Neuroendocrine Tumors
Not yet reported, Not yet reported Dana-Farber Cancer Institute 43 participants Est. completion 2019-03-29 3 sitesOther conditions: Pancreatic Neuroendocrine TumorView official trial listing → -
Completed NCT NCT00577278
A Phase II Study of Allo-HCT for B-Cell NHL Using Zevalin, Fludarabine and Melphalan
Not yet reported City of Hope Medical Center 41 participants Est. completion 2023-12-14 1 site Stand-aloneOther conditions: Graft Versus Host Disease, Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT00582738
Efficacy of Everolimus as Inhibitor of Fibrosis Progression in Liver Transplant Patients With Recurrence of Hepatitis C Viral Infection
Not yet reported Novartis Pharmaceuticals 43 participants Est. completion 2010-01 1 siteOther conditions: Recurrent Hepatitis CView official trial listing → -
Completed NCT NCT00583063
Interaction Study of Rapamycin and Sunitinib in Patients With Advanced Cancers
Not yet reported University of Chicago 23 participants Est. completion 2008-04 1 siteOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT00586443
BEP Study Phase I (Bevacizumab, Everolimus, Panitumumab)
Not yet reported Herbert Hurwitz, MD 56 participants Est. completion 2014-09 1 siteOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT00589563
Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer
Not yet reported City of Hope Medical Center 32 participants Est. completion 2012-02 2 sites Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Infection, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous Condition, Secondary Myelofibrosis, Small Intestine CancerView official trial listing → -
Completed NCT NCT00590174
Clopidogrel Use and Long-term Safety After Drug-Eluting Stents Implantation
Not yet reported Seung-Jung Park 1175 participants Est. completion 2010-04 20 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00591734
RAD001 Plus Bevacizumab in Metastatic Melanoma
Not yet reported SCRI Development Innovations, LLC 57 participants Est. completion 2011-10 15 sitesOther conditions: Metastatic MelanomaView official trial listing → -
Terminated NCT NCT00593008
Temsirolimus in Combination With Gemcitabine in Previously Untreated Metastatic Pancreatic Cancer
Not yet reported Massachusetts General Hospital 5 participants Est. completion 2009-10 1 siteOther conditions: Pancreatic AdenocarcinomaView official trial listing → -
Completed NCT NCT00593060
Temsirolimus (CCI-770, Torisel) Combined With Cetuximab in Cetuximab-Refractory Colorectal Cancer
Not yet reported Jeffrey W. Clark, MD 35 participants Est. completion 2010-11 2 sitesOther conditions: Colorectal Cancer, Colorectal AdenocarcinomaView official trial listing → -
Completed NCT NCT00596557
Everolimus and Low Dose CNI Compared With MMF and Full CNI Dose in Heart Transplanted Patients: One Year Follow up
Not yet reported Rabin Medical Center 20 participants Est. completion 2011-07 1 siteOther conditions: Chronic Rejection of Cardiac TransplantView official trial listing → -
Completed NCT NCT00598533
Efficacy Study of Rapamycin- vs. Zotarolimus-Eluting Stents to Reduce Coronary Restenosis
Not yet reported Deutsches Herzzentrum Muenchen 3002 participants Est. completion 2010-09 2 sitesOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00598676
3 Limus Agent Eluting Stents With Different Polymer Coating
Not yet reported Deutsches Herzzentrum Muenchen 2600 participants Est. completion 2009-04 2 sitesOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00598715
Efficacy Study of Two Different Strategies for Restenosis in Sirolimus-Eluting Stents
Not yet reported Deutsches Herzzentrum Muenchen 450 participants Est. completion 2009-08 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00600496
A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)
Not yet reported AstraZeneca 140 participants Est. completion 2025-12-18 4 sitesOther conditions: Breast Cancer, Breast Neoplasms, Colon Cancer, Colonic Cancer, Colon Neoplasms, Lung Cancer, Melanoma, Kidney CancerView official trial listing → -
Completed NCT NCT00602693
T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer
Not yet reported Masonic Cancer Center, University of Minnesota 41 participants Est. completion 2015-04-16 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma, Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00604357
CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal Impairment
Not yet reported University of Regensburg 27 participants Est. completion 2012-08 1 site Stand-aloneOther conditions: End Stage Liver Disease, Impaired Renal FunctionView official trial listing → -
Terminated NCT NCT00606333
Comparison of the Conor Sirolimus-eluting Coronary Stent to the Taxus Liberte Paclitaxel-eluting Coronary Stent in the Treatment of Coronary Artery Lesions
Not yet reported Cordis US Corp. 394 participants Est. completion 2012-10 2 sites Stand-aloneOther conditions: Coronary AtherosclerosisView official trial listing → -
Completed NCT NCT00607113
Avastin (Bevacizumab) and RAD001 (Everolimus) in Advanced Low or Intermediate Grade Neuroendocrine Carcinoma
Not yet reported M.D. Anderson Cancer Center 41 participants Est. completion 2011-10 1 siteOther conditions: Neuroendocrine CarcinomaView official trial listing → -
Completed NCT NCT00610012
Tumor Registry of Advanced Renal Cell Carcinoma
iOMEDICO AG 1500 participants Est. completion 2020-05-15 1 siteOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00610493
Bevacizumab and Temsirolimus in Patients With Advanced Malignancy
Not yet reported M.D. Anderson Cancer Center 193 participants Est. completion 2017-11-28 1 siteOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT00610948
Everolimus, Fluorouracil, Leucovorin, Panitumumab, and Oxaliplatin in Treating Patients With Tumors That Did Not Respond to Treatment
Not yet reported UNC Lineberger Comprehensive Cancer Center 74 participants Est. completion 2016-01 1 siteOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00611910
Efficacy Study of Drug-eluting and Bare Metal Stents in Bypass Graft Lesions
Not yet reported Deutsches Herzzentrum Muenchen 610 participants Est. completion 2011-03 4 sites Stand-aloneOther conditions: Arteriosclerosis of Arterial Coronary Artery Bypass GraftView official trial listing → -
Completed NCT NCT00612274
Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell Transplantation
Not yet reported Yale University 26 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: Stem Cell TransplantationView official trial listing → -
Completed NCT NCT00613132
Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MG
Not yet reported Annick Desjardins 78 participants Est. completion 2013-01 1 siteObstructive sleep apnea Other conditions: GlioblastomaView official trial listing → -
Completed NCT NCT00618345
Everolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported Mayo Clinic 35 participants Est. completion 2008-08Other conditions: Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00619268
Combination of Temsirolimus and Bevacizumab in Patient With Metastatic Renal Cell Carcinoma
Not yet reported Centre Leon Berard 160 participants Est. completion 2012-02 29 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00619528
HLA-Identical Sibling Renal Transplant Tolerance
Not yet reported Northwestern University 88 participants Est. completion 2023-09 1 site Stand-aloneOther conditions: Immunosuppression, Kidney Transplantation, Graft RejectionView official trial listing → -
Completed NCT NCT00621101
Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects
Not yet reported University Medicine Greifswald 24 participants Est. completion 2007-06 1 site Stand-aloneOther conditions: Pharmacokinetics, Drug Interactions, Hypercholesterolemia, ImmunosuppressionView official trial listing → -
Completed NCT NCT00622258
A Phase I Dose Escalation Study of RAD001 Administered in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Not yet reported Novartis Pharmaceuticals 13 participants Est. completion 2014-01 8 sitesOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT00622869
Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients
Not yet reported Novartis Pharmaceuticals 719 participants Est. completion 2012-04 91 sitesOther conditions: Liver TransplantationView official trial listing → -
Terminated NCT NCT00623012
Rapamycin for Prevention of Chronic Graft-Versus-Host Disease
Not yet reported, Not yet reported Yale University 2 participants Est. completion 2013-08 1 siteOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT00627900
Cost-Effectiveness Study in the Reduction of Coronary Restenosis With Sirolimus-Eluting Stents
Not yet reported Charite University, Berlin, Germany 958 participants 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00629525
RAD001 in Patients With Metastatic, Hormone-Refractory Prostate Cancer
Not yet reported Daniel George, MD 35 participants Est. completion 2010-01 1 siteOther conditions: Hormone Refractory Prostate CancerView official trial listing → -
Completed NCT NCT00630344
RAD001 and Bicalutamide for Androgen Independent Prostate Cancer
Not yet reported Dana-Farber Cancer Institute 36 participants Est. completion 2012-05 2 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00631371
Study Comparing Bevacizumab + Temsirolimus vs. Bevacizumab + Interferon-Alfa In Advanced Renal Cell Carcinoma Subjects
Not yet reported Pfizer 791 participants Est. completion 2015-04 172 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00632268
Low-dose RAD001(Everolimus) Plus Cisplatin-HDFL Chemotherapy for the First-line Treatment of Advanced Gastric Cancer
Not yet reported National Taiwan University Hospital 40 participants Est. completion 2012-12 1 siteOther conditions: Metastatic Gastric CancerView official trial listing → -
Completed NCT NCT00634244
Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported National Cancer Institute (NCI) 92 participants Est. completion 2014-10 20 sites Stand-aloneOther conditions: Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Erythroleukemia (M6a), Adult Pure Erythroid Leukemia (M6b), Recurrent Adult Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00634920
Evaluation of Early Conversion to Everolimus From Cyclosporine in de Novo Renal Transplant Recipients
Not yet reported Novartis Pharmaceuticals 204 participants Est. completion 2013-05 8 sitesOther conditions: Renal FunctionView official trial listing → -
Completed NCT NCT00635284
ABI-009 Trial in Patients With Advanced Non-hematologic Malignancies
Not yet reported Celgene 27 participants Est. completion 2011-06-01 2 sitesOther conditions: Solid TumorsView official trial listing → -
Status unknown NCT NCT00636922
Everolimus (RAD001) in Elderly Patients With Acute Myeloid Leukemia
Not yet reported Bayside Health 40 participants Est. completion 2014-01 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00638794
Assessment of Dual AntiPlatelet Therapy With Drug Eluting Stents
Cardiovascular Research Foundation, New York 8575 participants Est. completion 2013-01 8 sitesCardiovascular diseaseView official trial listing → -
Terminated NCT NCT00640978
Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer
Not yet reported M.D. Anderson Cancer Center 16 participants Est. completion 2010-03 1 siteOther conditions: Pancreatic CancerView official trial listing → -
Terminated NCT NCT00651482
Treatment of Refractory Metastatic Renal Cell Carcinoma With Bevacizumab and RAD001 (Everolimus)
Not yet reported Sandy Srinivas 10 participants Est. completion 2012-03 1 siteOther conditions: Kidney Neoplasms, Kidney (Renal Cell) CancerView official trial listing → -
No Longer Available NCT NCT00655252
Expanded Access Study of RAD001 in Metastatic Renal Cell Cancer Patients Who Are Intolerant of or Who Have Failed Despite Prior Vascular Endothelial Growth Factor Therapy
Novartis Pharmaceuticals 84 sitesOther conditions: Metastatic Renal Cell CancerView official trial listing → -
Completed NCT NCT00655655
Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors
Not yet reported Mayo Clinic 96 participants Est. completion 2018-01-11 1 siteOther conditions: Gastrinoma, Glucagonoma, Insulinoma, Metastatic Gastrointestinal Carcinoid Tumor, Metastatic Pheochromocytoma, Pancreatic Polypeptide Tumor, Recurrent Gastrointestinal Carcinoid Tumor, Recurrent Islet Cell Carcinoma, Recurrent Melanoma, Recurrent Neuroendocrine Carcinoma of the Skin, Recurrent Non-small Cell Lung Cancer, Recurrent Pheochromocytoma, Recurrent Renal Cell Cancer, Somatostatinoma, Stage III Neuroendocrine Carcinoma of the Skin, Stage IV Melanoma, Stage IV Non-small Cell Lung Cancer, Stage IV Renal Cell Cancer, Thyroid Gland Medullary Carcinoma, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00656643
Dose Ranging Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Diabetic Macular Edema
Not yet reported Santen Inc. 131 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: Diabetic Macular EdemaView official trial listing → -
Status unknown NCT NCT00657982
Phase II Study of RAD001 in a Neoadjuvant Setting in Men With Intermediate or High Risk Prostate Cancer
Not yet reported Sheba Medical Center 15 participants 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00658320
Concentration Controlled Everolimus With Reduced Dose Cyclosporine Versus Mycophenolate Mofetil With Standard Dose Cyclosporine in de Novo Renal Transplant Adult Recipients Treated With Basiliximab and Corticosteroids
Not yet reported Novartis 122 participants Est. completion 2012-05 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00659568
Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or Lymphoma
Not yet reported London Health Sciences Centre 28 participants Est. completion 2010-08 1 siteOther conditions: Breast Cancer, Endometrial Cancer, Kidney Cancer, Lung Cancer, Lymphoma, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00660478
Randomized Clinical Comparison of the Endeavor and the Cypher Coronary Stents in Non-selected Angina Pectoris Patients
Not yet reported Evald Hoej Christiansen 2342 participants Est. completion 2009-10 1 siteOther conditions: Ischemic Heart DiseaseView official trial listing → -
Completed NCT NCT00664963
YUKON-drug-eluting Stent Below The Knee - Randomised Double-blind Study
Not yet reported Herz-Zentrums Bad Krozingen 130 participants Est. completion 2010-04 3 sites Stand-aloneOther conditions: Arterial Occlusive DiseasesView official trial listing → -
Completed NCT NCT00667485
Rapamycin Plus Bevacizumab in Advanced Cancers
Not yet reported University of Chicago 28 participants Est. completion 2012-05 1 siteOther conditions: Advanced Cancer, Metastatic CancerView official trial listing → -
Completed NCT NCT00670423
A Study Using Tacrolimus, Sirolimus and Bortezomib as Acute Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Peripheral Blood Stem Cell (PBSC) Transplantation
Not yet reported Jennifer E. Schwartz 27 participants Est. completion 2013-10-16 1 siteOther conditions: Graft vs Host Disease, Peripheral Blood Stem Cell Transplantation, Transplantation, HomologousView official trial listing → -
Terminated NCT NCT00671112
Everolimus and Bortezomib in Treating Patients With Relapsed or Refractory Lymphoma
Not yet reported Brian Hill, MD, PhD 30 participants 1 siteOther conditions: 714leukemia, LymphomaView official trial listing → -
Terminated NCT NCT00672204
Raptiva and Sirolimus in Islet Transplantation for Type 1 Diabetes
Not yet reported, Not yet reported University of Minnesota 23 participants Est. completion 2012-08 1 site Stand-aloneOther conditions: Type 1 Diabetes Mellitus, HypoglycemiaView official trial listing → -
Terminated NCT NCT00674414
Trastuzumab With or Without Everolimus in Treating Women With Breast Cancer That Can Be Removed By Surgery
Not yet reported UNICANCER 82 participants 8 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00678769
Cixutumumab and Temsirolimus in Treating Patients With Locally Advanced or Metastatic Cancer
Not yet reported National Cancer Institute (NCI) 72 participants Est. completion 2015-10 2 sitesOther conditions: Malignant NeoplasmView official trial listing → -
Active, not recruiting NCT NCT00679042
Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol
Not yet reported CellTrans Inc. 21 participants Est. completion 2026-06-14 1 site Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00680758
Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer
Not yet reported Vanderbilt-Ingram Cancer Center 18 participants Est. completion 2010-12 4 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00681213
Tacrolimus/Sirolimus Versus Tacrolimus/Mycophenolate Mofetil (MMF) Versus Neoral/Sirolimus in Adult, Primary Kidney Transplantation
Not yet reported University of Miami 150 participants Est. completion 2002-12 1 site Stand-aloneOther conditions: Adult Primary Kidney TransplantationView official trial listing → -
Completed NCT NCT00688753
RAPTOR: RAD001 as Monotherapy in the Treatment of Advanced Papillary Renal Cell Tumors Program in Europe
Not yet reported Novartis Pharmaceuticals 92 participants Est. completion 2014-10 19 sitesOther conditions: Carcinoma, Renal Cell, Non Clear Cell Renal Carcinoma, Papillary Cell Renal Carcinoma, AdenocarcinomaView official trial listing → -
Completed NCT NCT00691015
Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant
Not yet reported Barbara Ann Karmanos Cancer Institute 48 participants Est. completion 2014-04 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Status unknown NCT NCT00693030
Optical Coherence Tomography for Drug Eluting Stent Safety
Not yet reported A.O. Ospedale Papa Giovanni XXIII 77 participants Est. completion 2008-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00693251
Optimal Stenting Strategy For True Bifurcation Lesions
Not yet reported Seung-Jung Park 420 participants Est. completion 2015-06 12 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00693433
Temsirolimus and Dexamethasone in Treating Patients With Recurrent or Refractory Multiple Myeloma
Not yet reported National Cancer Institute (NCI) 15 participants 1 siteOther conditions: Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple MyelomaView official trial listing → -
Status unknown NCT NCT00693446
A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus Corticosteroids
Not yet reported Nantes University Hospital 118 participants Est. completion 2017-04 1 siteOther conditions: Pancreas Transplantation, Kidney TransplantationView official trial listing → -
Completed NCT NCT00694005
Choice Of Optimal Strategy For Bifurcation Lesions With Normal Side Branch
Not yet reported Seung-Jung Park 504 participants Est. completion 2015-01 11 sitesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT00695344
Study to Evaluate Effect of Everolimus in Progression of Graft Vascular Illness on Patients With Heart Transplant
Not yet reported Fundacion Investigacion y Desarrollo 52 participants Est. completion 2010-06 8 sitesOther conditions: Cardiac TransplantView official trial listing → -
Completed NCT NCT00697112
Study Evaluating The Use Of Sirolimus In Recipients Of Kidney Allografts From Expanded Criteria Donors (ECD)
Pfizer 53 participants Est. completion 2012-12 8 sitesOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT00697372
SEA-SIDE: Sirolimus Versus Everolimus-eluting Stent Randomized Assessment in Bifurcated Lesions and Clinical SIgnificance of Residual siDE-branch Stenosis
Not yet reported Catholic University of the Sacred Heart 150 participants Est. completion 2010-04 1 siteCardiovascular disease Other conditions: Coronary StenosisView official trial listing → -
Completed NCT NCT00698607
Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing
Not yet reported Seoul National University Hospital 1466 participants Est. completion 2014-04 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00699491
Cixutumumab and Temsirolimus in Treating Patients With Locally Recurrent or Metastatic Breast Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 48 participants Est. completion 2018-02-14 192 sitesOther conditions: Male Breast Carcinoma, Recurrent Breast Carcinoma, Stage IV Breast Cancer AJCC v6 and v7View official trial listing → -
Completed NCT NCT00700258
Registry For Temsirolimus, Sunitinib, And Axitinib Treated Patients With Metastatic Renal Cell Carcinoma (mRCC), Mantle Cell Lymphoma (MCL), And Gastro-Intestinal Stroma Tumor (GIST) [STAR-TOR]
Pfizer 1520 participants Est. completion 2021-12-28 77 sitesOther conditions: Carcinoma, Renal Cell, Advanced, Lymphoma, Mantle-Cell, Gastrointestinal Stroma TumorsView official trial listing → -
Completed NCT NCT00702052
Safety and Efficacy of RAD001 in Participants With Mantle Cell Lymphoma Who Are Refractory or Intolerant to Velcade® Therapy
Not yet reported Novartis Pharmaceuticals 58 participants Est. completion 2012-04-20 31 sitesOther conditions: Lymphoma, Mantle- CellView official trial listing → -
Completed NCT NCT00703170
Phase I Study of DOXIL and Temsirolimus in Resistant Solid Malignancies
Not yet reported Washington University School of Medicine 28 participants Est. completion 2011-07 1 siteOther conditions: Resistant Solid MalignanciesView official trial listing → -
Completed NCT NCT00703625
Phase I Study of Docetaxel and Temsirolimus in Resistant Solid Malignancies
Not yet reported Washington University School of Medicine 26 participants Est. completion 2011-06-01 1 siteOther conditions: Resistant Solid MalignanciesView official trial listing → -
Completed NCT NCT00703807
Study of the Weekly Oral RAD001 in Combination With Oral Topotecan in Patients With Advanced or Recurrent Endometrial Cancers
Not yet reported Yale University 10 participants Est. completion 2010-05 1 siteOther conditions: Endometrial CancerView official trial listing → -
Active, not recruiting NCT NCT00706420
Islet Transplantation Alone (ITA) in Patients With Difficult to Control Type I Diabetes Mellitus Using a Glucocorticoid-free Immunosuppressive Regimen
Not yet reported City of Hope Medical Center 17 participants Est. completion 2026-10-12 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00708591
Study of Rapamycin Plus Ketoconazole in Advanced Cancers
Not yet reported University of Chicago 57 participants Est. completion 2008-12 1 siteOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT00708604
Islet After Kidney Transplantation (IAK) in Patients With Type 1 Diabetes
Not yet reported City of Hope Medical Center 3 participants Est. completion 2014-06 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00711490
Sirolimus to Treat Diabetic Macular Edema
Not yet reported, Not yet reported National Eye Institute (NEI) 5 participants Est. completion 2011-01 1 site Stand-aloneOther conditions: Diabetic RetinopathyView official trial listing → -
Terminated NCT NCT00712491
Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degeneration
Not yet reported, Not yet reported Santen Inc. 20 participants Est. completion 2010-03 1 site Stand-aloneOther conditions: Age-related Macular Degeneration, Choroidal NeovascularizationView official trial listing → -
Completed NCT NCT00713284
Study Evaluating Conversion From Tacrolimus to Sirolimus in Stable Kidney Transplant Recipients Receiving Myfortic
Not yet reported California Pacific Medical Center Research Institute 29 participants Est. completion 2010-11 1 siteOther conditions: Renal TransplantationView official trial listing → -
Terminated NCT NCT00713557
Shanghai Registry of Acute Coronary Events
Shanghai Jiao Tong University School of Medicine 20000 participants 1 siteCardiovascular disease Other conditions: Acute Coronary SyndromeView official trial listing → -
Completed NCT NCT00714025
A Single Arm, Multicenter, Phase II Trial of RAD001 as Monotherapy in the Palliative Treatment of Patients With TCC After Failure of Chemotherapy
Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 40 participants Est. completion 2012-01 1 siteOther conditions: Transitional Cell CarcinomaView official trial listing → -
Completed NCT NCT00714623
The SCRIPPS DES REAL WORLD Registry
Paul S Teirstein, MD 859 participants Est. completion 2012-04 1 siteCardiovascular disease Other conditions: Coronary Restenosis, Coronary ThrombosisView official trial listing → -
Terminated NCT NCT00714883
Conor Cobalt Chromium Reservoir Based Stent With Sirolimus Elution in Native Coronary Artery Lesions
Not yet reported Cordis US Corp. 3 participants Est. completion 2012-10 2 sitesOther conditions: Coronary DiseaseView official trial listing → -
Status unknown NCT NCT00715884
Study Comparing the CYPHER® ELITE™ to the CYPHER® Bx VELOCITY® Sirolimus-Eluting Stent Systems
Not yet reported Cordis US Corp. 678 participants Est. completion 2014-09 1 site Stand-aloneCardiovascular disease Other conditions: Coronary AtherosclerosisView official trial listing → -
Completed NCT NCT00716573
Efficacy Study of Everolimus on Renal Function in Heart Transplant Recipients With Established Chronic Renal Failure
Not yet reported Hospices Civils de Lyon 120 participants Est. completion 2014-04-17 1 siteOther conditions: Cardiac Transplantation, Chronic Renal InsufficiencyView official trial listing → -
Completed NCT NCT00723255
Bevacizumab and Temsirolimus in Treating Patients With Recurrent or Persistent Endometrial Cancer
Not yet reported National Cancer Institute (NCI) 53 participants Est. completion 2016-01-25 41 sitesOther conditions: Recurrent Endometrial CarcinomaView official trial listing → -
Terminated NCT NCT00727207
Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With First-Line or Second-Line Chemotherapy
Not yet reported Technical University of Munich 35 participants Est. completion 2014-09 1 siteOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00729248
The Differential Effects of 3 Different Immunosuppressive
Northwestern University 12 participants Est. completion 2010-01 1 siteOther conditions: Immunosuppression, Kidney TransplantationView official trial listing → -
Completed NCT NCT00729482
RAD001 (Everolimus) Salvage Monotherapy in Advanced Gastric Cancer (AGC) Who Failed Standard First-line Treatment
Not yet reported Asan Medical Center 54 participants Est. completion 2013-03 1 siteOther conditions: Stomach NeoplasmView official trial listing → -
Completed NCT NCT00729586
Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer
Not yet reported National Cancer Institute (NCI) 73 participants Est. completion 2017-02 108 sitesOther conditions: Endometrial Carcinoma, Recurrent Uterine Corpus Carcinoma, Stage IIIA Uterine Corpus Cancer, Stage IIIB Uterine Corpus Cancer, Stage IIIC1 Uterine Corpus Cancer, Stage IIIC2 Uterine Corpus Cancer, Stage IVA Uterine Corpus Cancer, Stage IVB Uterine Corpus CancerView official trial listing → -
Completed NCT NCT00729638
RAD001 and Lenalidomide in the Treatment of Subjects With Relapsed and Relapsed/Refractory Multiple Myeloma
Not yet reported Massachusetts General Hospital 28 participants Est. completion 2009-11 5 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00736970
Oral Deforolimus With Trastuzumab for Patients With HER2-positive Trastuzumab-Refractory Metastatic Breast Cancer (8669-009)
Not yet reported Merck Sharp & Dohme LLC 34 participants Est. completion 2011-05Other conditions: Breast Cancer, Breast NeoplasmsView official trial listing → -
Completed NCT NCT00738556
Spot Drug-Eluting Stenting for Long Coronary Stenoses
Not yet reported Cardiovascular Research Society, Greece 179 participants Est. completion 2007-09 2 sitesOther conditions: AngioplastyView official trial listing → -
Completed NCT NCT00743509
A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced Sarcoma
Not yet reported University of Michigan Rogel Cancer Center 49 participants Est. completion 2012-09 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT00749424
The Study of the Crushing Technique Application Using SES in Coronary Bifurcations.
Not yet reported Cordis US Corp. 350 participants Est. completion 2009-04 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00752362
Per-cutaneous Intervention Based Paclitaxel and Sirolimus-Eluting Versus Bare Stents for the Treatment of de Novo Coronary Lesions (PAINT)
Not yet reported Sahajanand Medical Technologies Limited 280 participants 11 sites Stand-aloneOther conditions: Coronary RestenosisView official trial listing → -
Completed NCT NCT00755443
Sirolimus-Eluting Stent Versus Standard Stent in Diabetic
Not yet reported Hospital San Carlos, Madrid 160 participants Est. completion 2005-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00756340
A Trial of Everolimus and Bevacizumab in Children With Recurrent Solid Tumors
Not yet reported St. Jude Children's Research Hospital 16 participants Est. completion 2015-09 1 siteOther conditions: Recurrent or Refractory Solid Tumors, CNS MalignanciesView official trial listing → -
Completed NCT NCT00759850
Drug Eluting Stent (DES) in Primary Angioplasty
Not yet reported, Not yet reported San Giuseppe Moscati Hospital 270 participants Est. completion 2007-12 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00761644
Doxil, Bevacizumab and Temsirolimus Trial
Not yet reported M.D. Anderson Cancer Center 200 participants Est. completion 2019-03-28 1 siteOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT00762632
Combination of Nilotinib (AMN107) and RAD001 in Patients With Acute Myeloid Leukemia
Not yet reported, Not yet reported Technical University of Munich 40 participants 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT00766337
Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degeneration
Not yet reported Santen Inc. 62 participants Est. completion 2010-03 1 site Stand-aloneOther conditions: Age-Related Macular Degeneration, Choroidal NeovascularizationView official trial listing → -
Completed NCT NCT00766649
Pilot Study of the Evaluation of Subconjunctival Sirolimus in the Treatment of Bilateral GA Associated With AMD
Not yet reported, Not yet reported National Eye Institute (NEI) 11 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Age-Related Macular DegenerationView official trial listing → -
Completed NCT NCT00768729
Safety of Immunosuppression Minimization in Children and Adolescents After Kidney Transplantation
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 7 participants Est. completion 2012-12 5 sites Stand-aloneOther conditions: Kidney Failure, Chronic, Kidney Transplantation, ImmunosuppressionView official trial listing → -
Completed NCT NCT00770120
S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery
Not yet reported SWOG Cancer Research Network 61 participants Est. completion 2014-04 129 sitesOther conditions: Malignant MesotheliomaView official trial listing → -
Completed NCT NCT00770263
Erlotinib and Temsirolimus for Solid Tumors
Not yet reported Washington University School of Medicine 46 participants Est. completion 2014-09 1 siteOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT00770731
Study of Temsirolimus, Topotecan, and Bortezomib
Not yet reported M.D. Anderson Cancer Center 80 participants Est. completion 2012-11 1 siteOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT00775073
Antiangiogenic Treatment of Hepatocellular Cancer With Bevacizumab and RAD001
Not yet reported Gerhard Treiber 33 participants Est. completion 2012-04 10 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT00775593
Clofarabine and Temsirolimus in Treating Older Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 60 participants Est. completion 2013-10-23 19 sitesOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00776373
Rapamycin in With High-Dose Etoposide and Cytarabine in Relapsed/Refractory Aggressive Lymphoid Malignancies
Not yet reported, Not yet reported Abramson Cancer Center at Penn Medicine 4 participants Est. completion 2009-12 1 siteOther conditions: ALL, Burkitt's Lymphoma, Lymphoblastic Leukemia, CMLView official trial listing → -
Withdrawn NCT NCT00777400
Pilot Trial to Assess Effect of CNI Conversion of Efalizumab on T Reg Cells
Not yet reported, Not yet reported University of California, San Francisco Est. completion 2009-04 1 site Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Completed NCT NCT00779194
Prospective Study of Rapamycin for the Treatment of SLE
Not yet reported State University of New York - Upstate Medical University 99 participants Est. completion 2015-12-16 1 siteOther conditions: Systemic Lupus Erythematosus (SLE)View official trial listing → -
Completed NCT NCT00780104
Sirolimus in Combination With MEC in High Risk Myeloid Leukemias
Not yet reported Abramson Cancer Center at Penn Medicine 16 participants Est. completion 2010-06 1 site Stand-aloneOther conditions: Myeloid Leukemias, AML, Leukemia, CMLView official trial listing → -
Status unknown NCT NCT00780429
Pharmacokinetics and Pharmacodynamics of MPA in Stable Renal Transplant Patients
Fondazione IRCCS Policlinico San Matteo di Pavia 54 participants 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Status unknown NCT NCT00781716
Safety and Efficacy Study of CYPHER® Sirolimus Stent and ENDEAVOR® Zotarolimus Stent in Patients With Acute ST Elevation Myocardial Infarction (STEMI) and Analysis of Current Status of Emergency PCI Green Channel for STEMI Patients in China
Not yet reported Beijing Chao Yang Hospital 1020 participants Est. completion 2011-05 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00781846
Trial of Deforolimus in Combination With Bevacizumab for Patients With Advanced Cancers (8669-010)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 17 participants Est. completion 2010-02Other conditions: Solid TumorView official trial listing → -
Completed NCT NCT00782275
Avastin and Temsirolimus Following Tyrosine Kinase Inhibitor Failure in Patients With Advanced Renal Cell Carcinoma
Not yet reported Beth Israel Deaconess Medical Center 41 participants Est. completion 2015-05 3 sitesOther conditions: Renal Cell Carcinoma, Kidney CancerView official trial listing → -
Completed NCT NCT00782626
Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas
Not yet reported Dana-Farber Cancer Institute 23 participants Est. completion 2012-08 10 sitesOther conditions: Glioma, Low-grade Glioma, AstrocytomaView official trial listing → -
Completed NCT NCT00784914
A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors
Not yet reported City of Hope Medical Center 12 participants Est. completion 2010-11 1 site Stand-aloneOther conditions: Brain and Central Nervous System Tumors, Metastatic CancerView official trial listing → -
Completed NCT NCT00784979
Panel Reactive Antibody (PRA) Reduction in Sensitized Patients Awaiting Renal Transplantation
Not yet reported Tampa General Hospital 26 participants Est. completion 2012-04 1 siteOther conditions: End Stage Renal DiseaseView official trial listing → -
Completed NCT NCT00787969
Rituximab, Cladribine, and Temsirolimus in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma
Not yet reported Alliance for Clinical Trials in Oncology 74 participants Est. completion 2017-06-15 144 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00788021
Protective Immunity Project 01
Emory University 124 participants Est. completion 2011-10 1 siteOther conditions: Kidney Transplantation, Immunity, ImmunosuppressionView official trial listing → -
Completed NCT NCT00788060
A Phase Ib Study of Rad001 and Sutent to Treat Renal Cell Carcinoma
Not yet reported Daniel George, MD 5 participants Est. completion 2012-12 1 siteOther conditions: Renal Cell CarcinomaView official trial listing → -
Withdrawn NCT NCT00788580
S0718 Pazopanib and Temsirolimus in Treating Patients With Advanced Solid Tumors
Not yet reported SWOG Cancer Research NetworkOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00789308
Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 24 participants Est. completion 2014-08-21 3 sites Stand-aloneOther conditions: Diabetes Mellitus, Type IView official trial listing → -
Completed NCT NCT00789828
Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)
Not yet reported Novartis Pharmaceuticals 117 participants Est. completion 2014-10 24 sitesOther conditions: Tuberous Sclerosis, Subependymal Giant Cell AstrocytomaView official trial listing → -
Completed NCT NCT00790036
Phase III Study of RAD001 Adjuvant Therapy in Poor Risk Patients With Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 Versus Matching Placebo After Patients Have Achieved Complete Response With First-line Rituximab-chemotherapy
Not yet reported Novartis Pharmaceuticals 742 participants Est. completion 2016-06-15 202 sitesOther conditions: Diffuse Large B-cell LymphomaView official trial listing → -
Completed NCT NCT00790400
Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)
Not yet reported Novartis Pharmaceuticals 118 participants Est. completion 2015-11 25 sitesOther conditions: Tuberous Sclerosis Complex (TSC), Lymphangioleiomyomatosis (LAM)View official trial listing → -
Withdrawn NCT NCT00790439
Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation After Kidney Transplant
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) Est. completion 2009-10 Stand-aloneOther conditions: Diabetes Mellitus, Type IView official trial listing → -
Completed NCT NCT00792766
Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM)
Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 20 participants Est. completion 2013-09 1 siteOther conditions: Tuberous Sclerosis, AngiolipomaView official trial listing → -
Active, not recruiting NCT NCT00792948
Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 97 participants Est. completion 2027-01-06 157 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Adult L1 Acute Lymphoblastic Leukemia, Adult L2 Acute Lymphoblastic Leukemia, Adult T Acute Lymphoblastic Leukemia, Recurrent Adult Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00793221
Non-acute Coronary occlusIon Treated By Everolimus ELuting Stent
Not yet reported Raul Moreno 207 participantsCardiovascular disease Other conditions: Coronary Occlusion, Percutaneous Coronary InterventionView official trial listing → -
Completed NCT NCT00795886
Rapamycin for Immunosuppression and B Cell Modulation Post Stem Cell Transplant for Acute Lymphoblastic Leukemia (ALL)
Not yet reported University of Utah 63 participants Est. completion 2010-03 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00796796
Temsirolimus and Radiation for Non-Small Cell Lung Cancer
Not yet reported Washington University School of Medicine 10 participants Est. completion 2011-07 1 siteOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT00798954
Treatment of Bifurcation Lesions by SINGLE STENT and KISSing Balloon Trial
Not yet reported Vulnerable Plaque Society 800 participants Est. completion 2010-03 17 sitesOther conditions: Ischemic Heart Disease, RestenosisView official trial listing → -
Completed NCT NCT00799188
CERTICOEUR: A Secondary Prevention Study of Skin Cancers in Heart Transplant Patients. Everolimus Versus Calcineurin Inhibitors Multicenter Trial
Not yet reported Hospices Civils de Lyon 175 participants 1 siteOther conditions: Cardiac Transplantation, Skin CancerView official trial listing → -
Completed NCT NCT00800722
A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.
Not yet reported University of California, Irvine 21 participants Est. completion 2014-06 1 siteOther conditions: Port Wine StainView official trial listing → -
Completed NCT NCT00800917
A Study of Temsirolimus and Bevacizumab in Recurrent Glioblastoma Multiforme
Not yet reported Rigshospitalet, Denmark 12 participants Est. completion 2010-02 1 siteOther conditions: Glioblastoma MultiformeView official trial listing → -
Completed NCT NCT00803010
Graft-Versus-Host Disease (GVHD) Prophylaxis After Allogeneic Peripheral Blood Hematopoietic Cell Transplantation
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 74 participants Est. completion 2012-12 1 siteOther conditions: Acute Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT00803816
Everolimus for the Treatment of Uveitis Unresponsive to Cyclosporine A
Not yet reported Carsten Heinz 12 participants Est. completion 2010-12 1 siteOther conditions: UveitisView official trial listing → -
Completed NCT NCT00804336
Pasireotide in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors
Not yet reported Dana-Farber Cancer Institute 22 participants Est. completion 2015-04 3 sitesOther conditions: Neuroendocrine Tumor, Carcinoid Tumor, Pancreatic Neuroendocrine TumorView official trial listing → -
Completed NCT NCT00805129
Everolimus (RAD001) in Metastatic Transitional Cell Carcinoma of the Urothelium
Not yet reported Memorial Sloan Kettering Cancer Center 46 participants Est. completion 2021-12-15 1 siteOther conditions: Bladder Cancer, Metastatic Transitional Cell CarcinomaView official trial listing → -
Terminated NCT NCT00807755
Everolimus, Carboplatin, and Etoposide in Treating Patients With Small Cell Lung Cancer or Other Advanced Solid Tumors
Not yet reported University of California, Davis 5 participants Est. completion 2011-12 1 siteOther conditions: Lung Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Terminated NCT NCT00808899
Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma
Not yet reported St. Jude Children's Research Hospital 4 participants Est. completion 2009-07 1 siteOther conditions: NeuroblastomaView official trial listing → -
Terminated NCT NCT00809185
RAD001(Everolimus) in Treating Patients With Myelodysplastic Syndromes
Not yet reported Case Comprehensive Cancer Center 7 participants Est. completion 2009-03 1 siteOther conditions: Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00811590
Pilot Study of mTOR Inhibitor Therapy in Peutz-Jeghers Syndrome
Not yet reported University of Utah 3 participants Est. completion 2011-03 1 siteOther conditions: Peutz-Jeghers SyndromeView official trial listing → -
Completed NCT NCT00811616
A Safety and Efficacy of Supralimus™ Core™ Sirolimus Eluting Stent at MAX DDHV Institute
Not yet reported Sahajanand Medical Technologies Limited 105 participants Est. completion 2008-03 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT00811915
Study to Compare the Safety and Efficacy of Sirolimus (Rapamune) to Tacrolimus (Advagraf) Associated to Mycophenolate Mofetil (CellCept) Between 12 and 36 Months After Kidney Transplantation
Not yet reported University Hospital, Rouen 65 participants Est. completion 2014-06 8 sites Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00812123
Calcineurin Free Immunosuppression in Renal Transplant Recipients
Not yet reported University Hospital, Basel, Switzerland 127 participants Est. completion 2005-07 1 site Stand-aloneChronic kidney disease Other conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00812786
Pharmacokinetics of Immunosuppressive Drugs in Heart Transplant Patients
Not yet reported University Hospital, Limoges 42 participants Est. completion 2012-05 12 sitesOther conditions: Heart TransplantView official trial listing → -
Completed NCT NCT00814788
Bicalutamide With or Without Everolimus in Treating Patients With Recurrent or Metastatic Prostate Cancer
Not yet reported University of California, Davis 24 participants Est. completion 2016-01 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00814944
A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) Model
Not yet reported Santen Inc. 143 participants Est. completion 2009-10 1 site Stand-aloneOther conditions: Dry EyeView official trial listing → -
Active, not recruiting NCT NCT00819546
RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDS
Not yet reported Richard Stone, MD 29 participants Est. completion 2026-12 3 sitesOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00820911
Efficacy and Safety of AEB071 Versus Cyclosporine in de Novo Renal Transplant Recipients
Not yet reported Novartis Pharmaceuticals 175 participants Est. completion 2012-07 28 sitesOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00821080
Vandetanib and Sirolimus in Patients With Recurrent Glioblastoma
Not yet reported Massachusetts General Hospital 33 participants Est. completion 2015-02 2 sites Stand-aloneOther conditions: GlioblastomaView official trial listing → -
Completed NCT NCT00823459
Everolimus in Treating Patients With Recurrent Low-Grade Glioma
Not yet reported Susan Chang 58 participants Est. completion 2017-11-13 1 siteOther conditions: Adult Diffuse Astrocytoma, Adult Mixed Glioma, Adult Oligodendroglioma, Adult Subependymal Giant Cell Astrocytoma, Recurrent Adult Brain NeoplasmView official trial listing → -
Status unknown NCT NCT00825773
A Study to Evaluate Safety and Efficacy of the ExcelTM Sirolimus Eluting Stent With a Biodegradable Polymer Versus Sirolimus Eluting Stent With Non-Biodegradable Polymer in the Treatment of Patients With de Novo Coronary Artery Lesions
Not yet reported JW Medical Systems Ltd 1944 participants Est. completion 2014-04 1 siteCardiovascular disease Other conditions: Ischemia, Cardiac DeathView official trial listing → -
Completed NCT NCT00827359
Biomarker Trial of Everolimus in Patients With Advanced Renal Cell Carcinoma
Not yet reported Beth Israel Deaconess Medical Center 25 participants Est. completion 2018-06 3 sitesOther conditions: Renal Cell Carcinoma, Renal CancerView official trial listing → -
Terminated NCT NCT00827567
Trial of RAD001 in Triple Negative Metastatic Breast Cancer
Not yet reported Milton S. Hershey Medical Center 6 participants Est. completion 2011-02 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00827684
Temsirolimus and Irinotecan for Treatment Resistant Patients With Metastatic Colorectal Cancer and KRAS Mutations
Not yet reported Vejle Hospital 50 participants Est. completion 2011-06 2 sitesOther conditions: Metastatic Colorectal CancerView official trial listing → -
Status unknown NCT NCT00828503
Certican® (Everolimus) Against Cytomegalovirus Disease in Renal Transplant Patients
Not yet reported Marcus Saemann 40 participants Est. completion 2014-06 1 siteOther conditions: Cytomegalovirus DiseaseView official trial listing → -
Terminated NCT NCT00828594
Global Study Looking at the Combination of RAD001 and Sorafenib to Treat Patients With Advanced Hepatocellular Carcinoma
Not yet reported Novartis Pharmaceuticals 130 participants Est. completion 2011-06 8 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT00830466
A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.
Not yet reported University of California, Irvine 22 participants Est. completion 2016-01 1 siteOther conditions: Port Wine StainView official trial listing → -
Completed NCT NCT00830895
RAD001 for Non-clear Cell Renal Cell Carcinoma (RCC)
Not yet reported Seoul National University Hospital 49 participants Est. completion 2012-12 1 siteOther conditions: Renal Cell CarcinomaView official trial listing → -
Terminated NCT NCT00831480
Everolimus (RAD001) For Advanced Renal Cell Carcinoma (RCC) Before Kidney Removal
Not yet reported Linda C. Higgins 15 participants Est. completion 2014-12 2 sitesOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00833651
Protective Immunity Project 02
Emory University 97 participants Est. completion 2011-10 1 siteOther conditions: Kidney Transplant, Immunology, ImmunosuppressionView official trial listing → -
Withdrawn NCT NCT00834496
Switching From One Type of Anti-rejection Drug (Tacrolimus or Cyclosporine) to Another (Sirolimus) Approximately 90-180 Days After Liver Transplantation
Thomas Jefferson University Est. completion 2010-01 1 siteOther conditions: Side Effects of Calcineurin Inhibitors, Renal Toxicity, Hepatic Fibrosis on Biopsy, Neurotoxicity, Post Transplant DiabetesView official trial listing → -
Terminated NCT NCT00836927
Extension Trial of Deforolimus (Ridaforolimus, MK-8669) in Participants With Advanced Cancer (MK-8669-038)
Not yet reported Merck Sharp & Dohme LLC 7 participants Est. completion 2018-02-04Other conditions: Advanced CancersView official trial listing → -
Completed NCT NCT00838539
Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid Tumors
Not yet reported Puma Biotechnology, Inc. 63 participants Est. completion 2013-12 5 sitesOther conditions: Neoplasms, Malignant CarcinomaView official trial listing → -
Terminated NCT NCT00838955
Temsirolimus for Relapsed/Refractory Hodgkin's Lymphoma
Not yet reported Loyola University 14 participants Est. completion 2017-10 1 siteOther conditions: Hodgkin's LymphomaView official trial listing → -
Terminated NCT NCT00843531
RAD001 and Erlotinib in Patients With Neuroendocrine Tumors
Not yet reported University of California, San Francisco 17 participants Est. completion 2016-08-20 1 siteOther conditions: Neuroendocrine TumorsView official trial listing → -
Withdrawn NCT NCT00855114
Everolimus in Treating Women With Breast Cancer That Can Be Removed by Surgery
Not yet reported Masonic Cancer Center, University of Minnesota Est. completion 2009-06 1 siteOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT00856505
Safety Study of Calcineurin Inhibitor Free GvHD Prophylaxis in Allogeneic Stem Cell Transplantation
Not yet reported, Not yet reported University Hospital Freiburg 38 participants Est. completion 2011-03 1 siteOther conditions: Hematologic DiseasesView official trial listing → -
Terminated NCT NCT00857259
The Efficacy of Oral Everolimus in Patients With Neovascular Age-related Macular Degeneration
Not yet reported Novartis Pharmaceuticals 16 participants 12 sitesOther conditions: Choroidal Neo-Vascular Age-onset Macular Degeneration, Age-related Macular DegenerationView official trial listing → -
Completed NCT NCT00858663
Radiation Therapy (IMRT) + RAD001 (Everolimus) + Cisplatin for Patients With Head and Neck Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 13 participants Est. completion 2013-07 1 siteOther conditions: Head and Neck CancerView official trial listing → -
Completed NCT NCT00859183
Oral Sirolimus for In-Stent Restenosis
Not yet reported Deutsches Herzzentrum Muenchen 300 participants Est. completion 2004-03 3 sitesOther conditions: Coronary RestenosisView official trial listing → -
Completed NCT NCT00861874
A Study of Decitabine in Combination With Escalating Doses of Rapamycin in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported University of Rochester 13 participants 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00862979
A Study Investigating the Renal Tolerability, Efficacy, and Safety of a CNI-free Versus a Standard Regimen in de Novo Heart Transplant (HTx) Recipients
Not yet reported Novartis Pharmaceuticals 162 participants Est. completion 2017-03-06 9 sitesOther conditions: Heart TransplantationView official trial listing → -
Completed NCT NCT00863655
Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory to Letrozole or Anastrozole
Not yet reported Novartis Pharmaceuticals 724 participants Est. completion 2014-12-04 200 sitesOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT00866684
Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive Protocol
Not yet reported Charite University, Berlin, Germany 44 participants Est. completion 2011-04-19 15 sites Stand-aloneOther conditions: Skin CancerView official trial listing → -
Completed NCT NCT00866879
Randomized Conversion of Calcineurin-Inhibitors in Renal Allograft Recipients
Not yet reported Northwestern University 275 participants Est. completion 2019-03 1 site Stand-aloneOther conditions: Renal Transplant RejectionView official trial listing → -
Status unknown NCT NCT00868829
Firebird2 Cobalt-Chromium Alloyed Sirolimus-Eluting Stent Registry Trial
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 5000 participants Est. completion 2013-03 1 siteOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00869999
Everolimus Plus Rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma
Not yet reported Massachusetts General Hospital 26 participants Est. completion 2011-11 2 sitesOther conditions: Diffuse Large B-cell LymphomaView official trial listing → -
Completed NCT NCT00870337
Everolimus in Treating Patients With Relapsed or Metastatic Endometrial Cancer
Not yet reported ARCAGY/ GINECO GROUP 44 participants 1 siteOther conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT00874562
Rapamycin in Relapsed Acute Lymphoblastic Leukemia
Not yet reported Dana-Farber Cancer Institute 6 participants Est. completion 2016-04 1 siteOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00876395
Everolimus in Combination With Trastuzumab and Paclitaxel in the Treatment of HER2 Positive Locally Advanced or Metastatic Breast Cancer
Not yet reported Novartis Pharmaceuticals 719 participants Est. completion 2017-10-23 140 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00876434
Subconjunctival Sirolimus for the Treatment of Autoimmune Active Anterior Uveiti
Not yet reported National Eye Institute (NEI) 5 participants Est. completion 2011-02-10 1 siteOther conditions: Anterior UveitisView official trial listing → -
Completed NCT NCT00879333
Safety and Efficacy of RAD001 (Everolimus) Monotherapy Plus Best Supportive Care in Patients With Advanced Gastric Cancer (AGC)
Not yet reported Novartis Pharmaceuticals 656 participants Est. completion 2014-01 122 sitesOther conditions: Advanced Gastric CancerView official trial listing → -
Completed NCT NCT00880282
Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responded to Treatment
Not yet reported National Cancer Institute (NCI) 39 participants 23 sitesOther conditions: Unspecified Childhood Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00886691
Bevacizumab With or Without Everolimus in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
Not yet reported GOG Foundation 150 participants Est. completion 2015-03-23 45 sitesOther conditions: Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal CarcinomaView official trial listing → -
Status unknown NCT NCT00887211
ProStent Coronary Drug-Eluting Stent
Not yet reported CCRF Consulting Co., Ltd. 290 participants Est. completion 2010-03 1 siteOther conditions: Coronary DiseaseView official trial listing → -
Terminated NCT NCT00887640
Impact of Temsirolimus Therapy on Circulating Tumor Cell Biology In Men With Castration Resistant Metastatic Prostate Cancer
Not yet reported Duke University 11 participants Est. completion 2012-08 2 sitesOther conditions: Prostate CancerView official trial listing → -
Status unknown NCT NCT00890253
Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver Transplantation
Not yet reported Armin Goralczyk 29 participants Est. completion 2013-01 1 siteOther conditions: Liver Transplantation, Chronic Renal InsufficiencyView official trial listing → -
Completed NCT NCT00890500
Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.
Not yet reported Fate Therapeutics 12 participants Est. completion 2013-10 2 sitesOther conditions: Hematologic Malignancies, Allogeneic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT00891696
Nutritional and Contractile Regulation of Muscle Growth
Not yet reported The University of Texas Medical Branch, Galveston 144 participants Est. completion 2015-03 1 siteOther conditions: SarcopeniaView official trial listing → -
Terminated NCT NCT00892801
Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer
Not yet reported Vanderbilt-Ingram Cancer Center 5 participants Est. completion 2011-02 2 sitesOther conditions: Lung Cancer, Metastatic CancerView official trial listing → -
Completed NCT NCT00895583
Study Evaluating A Planned Transition From Tacrolimus To Sirolimus In Kidney Transplant Recipients
Not yet reported Pfizer 254 participants Est. completion 2013-08 44 sites Stand-aloneOther conditions: Graft Rejection, Kidney Transplant, Renal Allograft Recipients, Renal TransplantView official trial listing → -
Completed NCT NCT00896012
Kidney Biopsy Controlled Trial of Calcineurin Inhibitor Withdrawal
Not yet reported University at Buffalo 58 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT00901849
Tarceva/Rapamycin for Children With Low-grade Gliomas With or Without Neurofibromatosis Type 1 (NF1)
Not yet reported Roger Packer 21 participants Est. completion 2012-10 1 siteOther conditions: Low-grade GliomasView official trial listing → -
Completed NCT NCT00903175
Efficacy and Safety Comparison of RAD001 Versus Sunitinib in the First-line and Second-line Treatment of Patients With Metastatic Renal Cell Carcinoma
Not yet reported Novartis Pharmaceuticals 471 participants Est. completion 2015-05 84 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Status unknown NCT NCT00903188
Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation
Not yet reported University Hospital, Antwerp 152 participants Est. completion 2015-04 5 sitesOther conditions: Renal TransplantationView official trial listing → -
Status unknown NCT NCT00905008
Long-Term Safety of Drug Eluting Stents in the "Real World" (FReIburger STent Registry)
University Hospital Freiburg 1502 participantsOther conditions: Stent ThrombosisView official trial listing → -
Completed NCT NCT00908466
Sirolimus as Therapeutic Approach to Uveitis
Not yet reported Johns Hopkins University 30 participants Est. completion 2013-02 1 site Stand-aloneOther conditions: Uveitis, Intermediate Uveitis, Posterior Uveitis, PanuveitisView official trial listing → -
Completed NCT NCT00909831
Hydroxychloroquine and Temsirolimus in Treating Patients With Metastatic Solid Tumors That Have Not Responded to Treatment
Not yet reported Abramson Cancer Center at Penn Medicine 40 participants Est. completion 2013-11 1 siteOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00912340
Phase II Trial of EVEROLIMUS ± Trastuzumab in Hormone-Refractory Metastatic Breast Cancer
Not yet reported Emory University 70 participants Est. completion 2017-07 4 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00915603
Trial of Paclitaxel/Bevacizumab +/- Everolimus for Patients With HER2-Negative Metastatic Breast Cancer
Not yet reported SCRI Development Innovations, LLC 113 participants Est. completion 2014-07 15 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Terminated NCT NCT00917163
SERIES III RUN-IN Clinical Trial: A Comparison of the Supralimus® Stent With the Xience V™ Stent
Not yet reported Sahajanand Medical Technologies Limited 13 participants Est. completion 2010-05 28 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00918333
Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma
Not yet reported, Not yet reported Mayo Clinic 124 participants Est. completion 2019-07-16 3 sitesObstructive sleep apnea Other conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, B-cell Adult Acute Lymphoblastic Leukemia, Hepatosplenic T-cell Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Primary Central Nervous System Non-Hodgkin Lymphoma, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Multiple Myeloma, Splenic Marginal Zone Lymphoma, T-cell Adult Acute Lymphoblastic Leukemia, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00919035
Single Agent Temsirolimus (Torisel®) in Chemotherapy-naïve Castration-Resistant Prostate Cancer Patients
Not yet reported Oncology Specialists, S.C. 21 participants Est. completion 2013-10 2 sitesOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00920309
Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to Therapy
Not yet reported, Not yet reported Yale University 21 participants Est. completion 2010-07 1 site Stand-aloneOther conditions: Autosomal Dominant Polycystic Kidney DiseaseView official trial listing → -
Terminated NCT NCT00921310
Temsirolimus and Pemetrexed for Recurrent or Refractory Non-Small Cell Lung Cancer
Not yet reported, Not yet reported Washington University School of Medicine 12 participants Est. completion 2016-04 1 siteOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Withdrawn NCT NCT00922129
Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in Renal Transplant Patients With Prostate Cancer
Not yet reported, Not yet reported St. Joseph's Healthcare Hamilton Est. completion 2011-01 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00923273
Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 42 participants Est. completion 2013-03-10 1 site Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT00923845
Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancer
Not yet reported National Cancer Institute (NCI) 25 participants Est. completion 2017-06-22 1 siteOther conditions: Renal Cell Carcinoma, Graft-Versus-Host Disease, Engraftment SyndromeView official trial listing → -
Terminated NCT NCT00926107
Study of the mTOR Inhibitor Temsirolimus (CCI-779) to Treat Ovarian Cancer With CA125 Only Relapse
Not yet reported Hellenic Cooperative Oncology Group 9 participants Est. completion 2011-10 12 sitesOther conditions: Ovarian CancerView official trial listing → -
Completed NCT NCT00927823
A Trial To Assess Safety And Tolerability Of PF-04691502 In Cancer Patients
Not yet reported Pfizer 37 participants Est. completion 2012-04 7 sitesOther conditions: CancerView official trial listing → -
Completed NCT NCT00927966
RAD001 in Combination With CP-751,871 in Patients Wtih Advanced Sarcomas and Other Malignant Neoplasms
Not yet reported Suzanne George, MD 21 participants Est. completion 2011-01 1 siteOther conditions: Sarcoma, Solid TumorView official trial listing → -
Completed NCT NCT00928018
Tacrolimus/Sirolimus/Methotrexate vs Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma
Not yet reported Dana-Farber Cancer Institute 139 participants Est. completion 2014-11 5 sitesOther conditions: Non-hodgkin Lymphoma, Hodgkin LymphomaView official trial listing → -
Completed NCT NCT00928798
Topical Rapamycin for Fibrofolliculomas
Not yet reported Maastricht University Medical Center 19 participants Est. completion 2011-08 2 sitesOther conditions: Birt-Hogg-Dubé SyndromeView official trial listing → -
Status unknown NCT NCT00930475
Everolimus (RAD001) and Carboplatin in Pretreated Metastatic Breast Cancer
Not yet reported, Not yet reported Charite University, Berlin, Germany 54 participants 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00930930
Cisplatin and Paclitaxel With or Without Everolimus in Treating Patients With Stage II or Stage III Breast Cancer
Not yet reported Vanderbilt-Ingram Cancer Center 145 participants Est. completion 2014-10 8 sitesOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT00931255
Tacrolimus to Sirolimus Conversion for Delayed Graft Function
Not yet reported University of Maryland, Baltimore 32 participants Est. completion 2014-07 1 siteOther conditions: Kidney Transplant, Delayed Graft FunctionView official trial listing → -
Terminated NCT NCT00933374
Trial to Evaluate Paclitaxel Plus RAD001 in Urothelial Carcinoma
Not yet reported Heinrich-Heine University, Duesseldorf 28 participants Est. completion 2013-09 6 sitesOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT00933777
SORAVE - Sorafenib and Everolimus in Solid Tumors
Not yet reported University of Cologne 36 participants Est. completion 2015-02 1 siteOther conditions: Unspecified Adult Solid Tumor, Protocol Specific, Non-Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT00934791
Polycystic Liver Disease in Kidney Transplant
Not yet reported Mayo Clinic 2 participants Est. completion 2012-12 1 siteOther conditions: Polycystic Liver DiseaseView official trial listing → -
Terminated NCT NCT00934895
Phase I/II Study of Weekly Abraxane and RAD001 in Women With Locally Adv. or Metastatic Breast Ca
Not yet reported, Not yet reported Rutgers, The State University of New Jersey 27 participants Est. completion 2015-08-12 3 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00935792
Everolimus and Alemtuzumab in Treating Patients With Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported, Not yet reported Mayo Clinic 28 participants Est. completion 2015-12 2 sitesOther conditions: Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00935961
RAD001 (Everolimus) + Docetaxel + Cisplatin as Induction Chemotherapy in Patients With Local-Regional Advanced Head and Neck Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 18 participants Est. completion 2013-08 5 sitesOther conditions: HEAD & NECK CancerView official trial listing → -
Completed NCT NCT00936702
Carboplatin, Paclitaxel, and Everolimus in Treating Patients With Previously Untreated Cancer of Unknown Primary
Not yet reported Alliance for Clinical Trials in Oncology 46 participants Est. completion 2013-08 141 sitesOther conditions: Carcinoma of Unknown Primary OriginView official trial listing → -
Completed NCT NCT00936858
RAD001 for Patients With Radioiodine Refractory Thyroid Cancer
Not yet reported Dana-Farber Cancer Institute 50 participants Est. completion 2020-02-27 4 sitesOther conditions: Thyroid CancerView official trial listing → -
Terminated NCT NCT00938119
Care China-Diabetes
Johnson & Johnson Medical, China 1603 participants Est. completion 2012-12 46 sitesCardiovascular disease Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00940381
Sirolimus and Cetuximab in Advanced Malignancies
Not yet reported M.D. Anderson Cancer Center 165 participants Est. completion 2014-05 1 site Stand-aloneOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT00942682
Sorafenib in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors
Not yet reported Dana-Farber Cancer Institute 21 participants Est. completion 2013-03 1 siteOther conditions: Neuroendocrine Tumor, Carcinoid Tumor, Pancreatic Neuroendocrine TumorView official trial listing → -
Completed NCT NCT00942734
Trial of RAD001 and Erlotinib With Recurrent Head and Neck Squamous Cell Carcinoma
Not yet reported M.D. Anderson Cancer Center 49 participants Est. completion 2014-11 1 siteOther conditions: Head And Neck CancerView official trial listing → -
Status unknown NCT NCT00942747
Temsirolimus in Recurrent Primary Central Nervous System (CNS) Lymphoma
Not yet reported Charite University, Berlin, Germany 37 participants Est. completion 2014-06 6 sitesOther conditions: Recurrent or Refractory Primary CNS LymphomaView official trial listing → -
Completed NCT NCT00943956
Everolimus, Bicalutamide, and Leuprolide Acetate in Treating Patients Undergoing Radiation Therapy For High-Risk Locally Advanced Prostate Cancer
Not yet reported Institut du Cancer de Montpellier - Val d'Aurelle 30 participants Est. completion 2012-12 1 siteOther conditions: Prostate CancerView official trial listing → -
Withdrawn NCT NCT00949026
Assessment of Systemically Administered Torisel Delivery to Brain Tumors by Intratumoral Microdialysis
Not yet reported Emory University Est. completion 2010-05 1 siteOther conditions: Brain NeoplasmsView official trial listing → -
Completed NCT NCT00949949
Everolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable Solid Tumors Refractory to Standard Therapy
Not yet reported Mayo Clinic 38 participants Est. completion 2014-07 3 sitesOther conditions: Cholangiocarcinoma of the Gallbladder, Localized Gallbladder Cancer, Unresectable Gallbladder Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Terminated NCT NCT00954512
Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Participants With Advanced Solid Tumors (P04722, MK-7454-004)
Not yet reported, Not yet reported Merck Sharp & Dohme LLC 15 participants Est. completion 2011-06-07Other conditions: NeoplasmsView official trial listing → -
Status unknown NCT NCT00954707
CYPRESS - CYPHER for Evaluating Sustained Safety
Not yet reported Cordis US Corp. 2509 participants Est. completion 2016-03 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00955773
A Study of the GSK MEK Inhibitor GSK1120212 and Everolimus in Cancer Subjects
Not yet reported GlaxoSmithKline 64 participants Est. completion 2011-11-08 3 sitesOther conditions: CancerView official trial listing → -
Terminated NCT NCT00956293
Study to Evaluate the Efficacy, Safety and Tolerability of Everolimus in de Novo Renal Transplant Recipients Participating in the Eurotransplant Senior Program
Not yet reported Novartis Pharmaceuticals 207 participants Est. completion 2013-03 9 sitesOther conditions: Renal TransplantationView official trial listing → -
Withdrawn NCT NCT00957320
Study of Sirolimus With PEG-Asparaginase in Acute Lymphoblastic Leukemia (ALL)
Not yet reported Emory University Est. completion 2012-08 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00960648
Registry to Evaluate Efficacy of Xience/Promus Versus Cypher in Reducing Late Loss After Stenting
Seoul National University Hospital 3056 participants Est. completion 2014-01 18 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00962507
Panobinostat and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma
Not yet reported City of Hope Medical Center 11 participants Est. completion 2013-01 2 sitesOther conditions: Lymphoma, Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00965094
Efficacy and Safety of Everolimus+EC-MPS After Early CNI Elimination vs EC-MPS +Tacrolimus in Renal Transplant Recipients
Not yet reported Novartis Pharmaceuticals 36 participants Est. completion 2013-06 3 sitesOther conditions: Chronic Renal FailureView official trial listing → -
Completed NCT NCT00967044
Panobinostat (LBH589) Plus Everolimus (RAD001) in Patients With Relapsed and Refractory Lymphoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2014-03 1 siteOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00967902
Safety and Effectiveness Study of Combo Bio-engineered Sirolimus Eluting Stent
Not yet reported OrbusNeich 180 participants Est. completion 2015-09 1 site Stand-aloneOther conditions: Coronary Artery LesionsView official trial listing → -
Completed NCT NCT00968253
RAD001 Study in Treatment of Relapsed or Refractory Acute Lymphocytic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 24 participants Est. completion 2015-12 1 siteOther conditions: Leukemia, Acute Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00968591
Pharmacokinetics of Everolimus in Subjects With Hepatic Insufficiency
Not yet reported Novartis Pharmaceuticals 34 participants 3 sitesOther conditions: Hepatic InsufficiencyView official trial listing → -
Completed NCT NCT00971789
Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes
Not yet reported National Cancer Institute (NCI) 18 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: Cowden's Disease, Hamartoma Syndrome, MultipleView official trial listing → -
Terminated NCT NCT00972335
Trial of the Combination of Bevacizumab and Everolimus in Patients With Refractory, Progressive Intracranial Meningioma
Not yet reported SCRI Development Innovations, LLC 18 participants Est. completion 2014-07 7 sitesOther conditions: Intracranial MeningiomaView official trial listing → -
Completed NCT NCT00973076
Study to Assess the Safety and Tolerability of the Tor Kinase Inhibitor AZD8055
Not yet reported AstraZeneca 19 participants Est. completion 2010-12 1 siteOther conditions: Cancer, Solid Tumors, Advanced Solid MalignanciesView official trial listing → -
Status unknown NCT NCT00973713
Study of RAD001 in Advanced Cholangiocarcinoma: RADiChol
Not yet reported Austin Health 27 participants Est. completion 2012-03 1 siteOther conditions: CholangiocarcinomaView official trial listing → -
Terminated NCT NCT00973804
Pilot Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Matched Unrelated Double Cord Blood Transplant for the Treatment of Leukemias, Lymphomas, and Pre-Malignant Blood Disorders
Not yet reported National Cancer Institute (NCI) 4 participants Est. completion 2013-05-20 1 siteOther conditions: Leukemia, Non-Hodgkins Lymphoma, Hodgkins Lymphoma, MDS, Multiple MyelomaView official trial listing → -
Completed NCT NCT00975819
Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies
Not yet reported Denise Martin Adams 61 participants Est. completion 2020-10 2 sites Stand-aloneOther conditions: Kaposiform Hemangioendotheliomas, Tufted Angioma, Capillary Venous Lymphatic Malformation, Venous Lymphatic Malformation, Microcystic Lymphatic Malformation, Mucocutaneous Lymphangiomatosis and Thrombocytopenia, Capillary Lymphatic Arterial Venous Malformations, PTEN Overgrowth Syndrome With Vascular Anomaly, Lymphangiectasia SyndromesView official trial listing → -
Completed NCT NCT00976248
Everolimus (RAD001) in Primary Therapy of Waldenstrom's Macroglobulinemia
Not yet reported Dana-Farber Cancer Institute 33 participants Est. completion 2018-07 1 siteOther conditions: Waldenstrom's MacroglobulinemiaView official trial listing → -
Completed NCT NCT00976573
Carboplatin, Paclitaxel, and Bevacizumab With or Without Everolimus in Treating Patients With Metastatic Malignant Melanoma
Not yet reported Alliance for Clinical Trials in Oncology 149 participants Est. completion 2015-09 310 sitesOther conditions: Melanoma (Skin)View official trial listing → -
Completed NCT NCT00976755
Everolimus as First-Line Therapy in Treating Patients With Prostate Cancer
Not yet reported Swiss Cancer Institute 37 participants Est. completion 2019-08-08 13 sitesOther conditions: Prostate CancerView official trial listing → -
Active, not recruiting NCT NCT00977574
Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
Not yet reported National Cancer Institute (NCI) 349 participants Est. completion 2027-03-06 230 sitesObstructive sleep apnea Other conditions: Endometrial Adenocarcinoma, Endometrial Adenosquamous Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Recurrent Malignant Uterine Corpus NeoplasmView official trial listing → -
Active, not recruiting NCT NCT00977691
Haploidentical PBMC Transplant for Severe Congenital Anemias
Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 23 participants Est. completion 2026-09-10 1 site Stand-aloneOther conditions: Sickle Cell AnemiaView official trial listing → -
Completed NCT NCT00977938
The Dual Antiplatelet Therapy Study (DAPT Study)
Not yet reported Baim Institute for Clinical Research 25682 participants Est. completion 2014-06 256 sitesCardiovascular diseaseView official trial listing → -
Terminated NCT NCT00978432
Epigenetic Modulation in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Not yet reported Anne Beaven, MD 50 participants Est. completion 2016-03 1 siteOther conditions: Diffuse Large B-cell LymphomaView official trial listing → -
Completed NCT NCT00979966
Study in Non-Clear Cell Renal Carcinoma (Ncc-RCC) Temsirolimus Versus Sunitinib
Not yet reported Central European Society for Anticancer Drug Research 22 participants 14 sitesOther conditions: Non-clear Cell Renal Cell CancerView official trial listing → -
Completed NCT NCT00980460
Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer
Not yet reported National Cancer Institute (NCI) 236 participants Est. completion 2026-03-31 209 sitesOther conditions: PRETEXT I Hepatoblastoma, PRETEXT II Hepatoblastoma, PRETEXT III Hepatoblastoma, PRETEXT IV HepatoblastomaView official trial listing → -
Completed NCT NCT00981162
Sorafenib Tosylate and Everolimus in Treating Patients With Advanced Solid Tumors and Metastatic Pancreatic Cancer That Does Not Respond to Gemcitabine Hydrochloride
Not yet reported Roswell Park Cancer Institute 12 participants Est. completion 2012-12 2 sitesOther conditions: Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage IV Pancreatic Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Status unknown NCT NCT00982631
A Study of Combination of Temsirolimus (Torisel®) and Pegylated Liposomal Doxorubicin (PLD, Doxil®/Caelyx®) in Advanced or Recurrent Breast, Endometrial and Ovarian Cancer
Not yet reported Radboud University Medical Center 30 participants Est. completion 2012-08 1 siteOther conditions: Advanced/Recurrent Breast Cancer, Endometrial Cancer, Ovarian CancerView official trial listing → -
Completed NCT NCT00985192
Everolimus in Treating Patients With Previously Treated Unresectable or Metastatic Esophageal Cancer or Stomach Cancer
Not yet reported Translational Oncology Research International 49 participants Est. completion 2014-05 18 sitesOther conditions: Esophageal Cancer, Gastric CancerView official trial listing → -
Terminated NCT NCT00985374
A Multiple Ascending Dose Study of the mTOR Inhibitor (RAD001) in Combination With R1507 in Patients With Advanced Solid Tumors
Not yet reported Hoffmann-La Roche 11 participants Est. completion 2013-06 3 sitesOther conditions: NeoplasmsView official trial listing → -
Completed NCT NCT00986050
Comparison of Drug Eluting and Bare Metal Stents With or Without Abciximab in ST Elevation Myocardial Infarction
Not yet reported Catharina Ziekenhuis Eindhoven 907 participants Est. completion 2009-07 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00993343
Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantation
Not yet reported Karolinska Institutet 215 participants Est. completion 2015-04 1 siteOther conditions: Graft-versus-host Disease, SurvivalView official trial listing → -
Completed NCT NCT00993499
Trial of Continuous Once Daily Oral Treatment Using BIBW 2992 (Afatinib) Plus Sirolimus (Rapamune®) in Patients With Non-small Cell Lung Cancer Harbouring an EGFR Mutation and/or Disease Progression Following Prior Erlotinib or Gefitinib
Not yet reported Boehringer Ingelheim 44 participants Est. completion 2014-09 8 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Withdrawn NCT NCT00995059
Bortezomib Before Donor Stem Cell Transplant in Treating Patients With Multiple Myeloma
Not yet reported, Not yet reported Mayo Clinic Stand-aloneOther conditions: Multiple Myeloma, Refractory Multiple MyelomaView official trial listing → -
Terminated NCT NCT00996346
Phase I/II Study of Irinotecan and Temsirolimus in Patients With Refractory Sarcomas
Not yet reported New Mexico Cancer Research Alliance 17 participants Est. completion 2013-11 1 siteOther conditions: SarcomaView official trial listing → -
Completed NCT NCT00997711
Evaluation of Diabetic Effects on Clinical Outcomes After Sirolimus-Eluting Stents in the AsIAN Population
Not yet reported Seung-Jung Park 953 participants Est. completion 2012-06 14 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00997763
Comparison of Everolimus-Eluting Stent vs Sirolimus-Eluting Stent in Patients With DIABETES Mellitus
Not yet reported Seung-Jung Park 300 participants Est. completion 2015-08 18 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00998036
Study of Temsirolimus, Erlotinib and Cisplatin in Solid Tumors
Not yet reported Columbia University 9 participants Est. completion 2012-10 1 siteOther conditions: Triple Negative Breast CancerView official trial listing → -
Status unknown NCT NCT00999258
Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant Recipients
Not yet reported Temple University 50 participants Est. completion 2011-06 1 siteOther conditions: Glomerular Filtration Rate, Chronic Allograft NephropathyView official trial listing → -
Completed NCT NCT00999882
Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of Tor Kinase Inhibitor in Liver Cancer Patients
Not yet reported AstraZeneca 26 participants Est. completion 2011-12 3 sitesOther conditions: Cancer, Advanced Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT01005199
Sorafenib Tosylate With or Without Everolimus in Treating Patients With Localized, Unresectable, or Metastatic Liver Cancer
Not yet reported Swiss Cancer Institute 106 participants Est. completion 2016-03 15 sitesOther conditions: Liver CancerView official trial listing → -
Completed NCT NCT01005706
Sirolimus Conversions in African-American Renal Transplant Recipients
Not yet reported Medical University of South Carolina 40 participants Est. completion 2014-07 1 siteOther conditions: Absence; KidneyView official trial listing → -
Completed NCT NCT01007942
Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer
Not yet reported Novartis Pharmaceuticals 569 participants Est. completion 2015-06 161 sitesOther conditions: HER2/Neu Over-expressing Locally Advanced Breast Cancer, Metastatic Breast CancerView official trial listing → -
Completed NCT NCT01008917
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma
Not yet reported University of California, San Francisco 25 participants Est. completion 2013-06-27 2 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT01009346
RAD001 in Combination With Cetuximab and Cisplatin in Recurrent and Metastatic SCCHN
Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 9 participants Est. completion 2011-03 1 siteOther conditions: Head and Neck CancerView official trial listing → -
Terminated NCT NCT01009801
Transarterial Chemoembolization With Doxorubicin With or Without Everolimus in Treating Patients With Liver Cancer
Not yet reported, Not yet reported Swiss Cancer Institute 27 participants Est. completion 2015-06 8 sitesOther conditions: Liver CancerView official trial listing → -
Terminated NCT NCT01009957
Everolimus on CKD Progression in ADPKD Patients
Not yet reported, Not yet reported A. Manzoni Hospital 71 participants Est. completion 2015-06 7 sitesOther conditions: Polycystic Kidney DiseasesView official trial listing → -
Completed NCT NCT01010126
Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell Cancer
Not yet reported National Cancer Institute (NCI) 252 participants Est. completion 2017-03-13 61 sitesObstructive sleep apnea Other conditions: Adult Hepatocellular Carcinoma, Advanced Adult Hepatocellular Carcinoma, Endometrial Serous Adenocarcinoma, Localized Non-Resectable Adult Liver Carcinoma, Lung Carcinoid Tumor, Malignant Pancreatic Gastrinoma, Malignant Pancreatic Glucagonoma, Malignant Pancreatic Insulinoma, Malignant Pancreatic Somatostatinoma, Metastatic Digestive System Neuroendocrine Tumor G1, Ovarian Endometrioid Adenocarcinoma, Ovarian Seromucinous Carcinoma, Ovarian Serous Surface Papillary Adenocarcinoma, Pancreatic Alpha Cell Adenoma, Pancreatic Beta Cell Adenoma, Pancreatic Delta Cell Adenoma, Pancreatic G-Cell Adenoma, Pancreatic Polypeptide Tumor, Recurrent Adult Liver Carcinoma, Recurrent Digestive System Neuroendocrine Tumor G1, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Pancreatic Neuroendocrine Carcinoma, Recurrent Primary Peritoneal Carcinoma, Recurrent Uterine Corpus Carcinoma, Regional Digestive System Neuroendocrine Tumor G1, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Cancer, Stage IIIA Primary Peritoneal Cancer, Stage IIIA Uterine Corpus Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Cancer, Stage IIIB Primary Peritoneal Cancer, Stage IIIB Uterine Corpus Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Cancer, Stage IIIC Primary Peritoneal Cancer, Stage IIIC Uterine Corpus Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Cancer, Stage IV Primary Peritoneal Cancer, Stage IVA Uterine Corpus Cancer, Stage IVB Uterine Corpus CancerView official trial listing → -
Completed NCT NCT01014234
Rapamycin and Regulatory T Cells in Kidney Transplantation
Not yet reported Fondazione IRCCS Policlinico San Matteo di Pavia 56 participants Est. completion 2013-06 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT01014351
Study of Everolimus With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma
Not yet reported SCRI Development Innovations, LLC 70 participants Est. completion 2013-08 12 sitesOther conditions: Metastatic MelanomaView official trial listing → -
Terminated NCT NCT01015664
Combination of Cisplatin, Cetuximab and Temsirolimus in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Not yet reported, Not yet reported University of Tennessee Cancer Institute 11 participants Est. completion 2012-12 1 siteOther conditions: Squamous Cell Carcinoma of the Head and NeckView official trial listing → -
Completed NCT NCT01016015
Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma
Not yet reported National Cancer Institute (NCI) 178 participants Est. completion 2014-07 24 sitesObstructive sleep apnea Other conditions: Recurrent Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue SarcomaView official trial listing → -
Completed NCT NCT01016769
Temsirolimus + Weekly Paclitaxel + Carboplatin for Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)
Not yet reported, Not yet reported Memorial Sloan Kettering Cancer Center 48 participants Est. completion 2018-06 5 sitesOther conditions: Squamous Cell Cancer, Head and Neck CancerView official trial listing → -
Completed NCT NCT01017029
Everolimus in de Novo Heart Transplant Recipients
Not yet reported Novartis Pharmaceuticals 182 participants Est. completion 2013-12 12 sitesOther conditions: Cardiac TransplantationView official trial listing → -
Completed NCT NCT01019434
Radiation Therapy and Temsirolimus or Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 111 participants Est. completion 2014-03 13 sitesOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Terminated NCT NCT01020305
Temsirolimus to Reverse Androgen Insensitivity for Castration-resistant Prostate Cancer
Not yet reported, Not yet reported Sandy Srinivas 5 participants Est. completion 2012-04 1 siteOther conditions: Prostate Cancer, Prostatic Neoplasms, Castrate-resistant Prostate Cancer (CRPC), Androgen-insensitive Prostate Cancer, Hormone-refractory Prostate Cancer, Metastatic DiseaseView official trial listing → -
Terminated NCT NCT01021930
Comparison of Diabetes Mellitus and Non-diabetes Mellitus Patients for DES Surface COVERage by OCT
Not yet reported Harbin Medical University 70 participants Est. completion 2010-12 1 siteOther conditions: Coronary Heart Disease, Diabetes MellitusView official trial listing → -
Completed NCT NCT01022996
Study of RAD001 in Patients With Relapsed/Refractory Hodgkin Lymphoma That Has Progressed After High-dose Chemotherapy and Autologous Stem Cell Transplant and/or After Gemcitabine- or Vinorelbine- or Vinblastine-based Treatment.
Not yet reported Novartis Pharmaceuticals 57 participants Est. completion 2014-11 16 sitesOther conditions: Hodgkin LymphomaView official trial listing → -
Completed NCT NCT01023815
Once-a-day Regimen With Everolimus, Low Dose Cyclosporine and Steroids in Comparison With Steroid Withdrawal or Twice a Day Regimen With Everolimus, Low Dose Cyclosporine and Steroids.
Not yet reported Novartis 330 participants Est. completion 2012-07 28 sitesOther conditions: de Novo Kidney Transplant Recipients, Renal TransplantationView official trial listing → -
Terminated NCT NCT01023919
Assessment of Surface Coverage of Two Types of Drug-eluting Stent in Diabetes Mellitus and Non-Diabetes Mellitus
Not yet reported Harbin Medical University 120 participants Est. completion 2010-12 1 siteCardiovascular disease Other conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT01024179
Relationship Between Initial Plaque Characteristics and Stent Surface Coverage Patterns
Not yet reported Harbin Medical University 90 participants Est. completion 2010-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01024946
Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity
Not yet reported Memorial Sloan Kettering Cancer Center 11 participants Est. completion 2012-07 3 sitesOther conditions: Malignant Pleural MesotheliomaView official trial listing → -
Completed NCT NCT01025453
Combination of Temsirolimus and Sorafenib in the Treatment of Radioactive Iodine Refractory Thyroid Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 37 participants Est. completion 2018-01-16 5 sitesOther conditions: Thyroid CancerView official trial listing → -
Completed NCT NCT01025817
Non-inferiority Study of Safety and Efficacy of Everolimus With Low Dose Tacrolimus to Mycophenolate Mofetil With Standard Dose Tacrolimus in Kidney Transplant Recipients
Not yet reported Novartis Pharmaceuticals 613 participants Est. completion 2013-03 50 sitesOther conditions: Kidney TransplantView official trial listing → -
Completed NCT NCT01026402
Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of AZD2014
Not yet reported AstraZeneca 172 participants Est. completion 2014-08 2 sitesOther conditions: Advanced Solid MalignanciesView official trial listing → -
Completed NCT NCT01026623
Cixutumumab and Temsirolimus in Treating Patients With Metastatic Prostate Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 16 participants Est. completion 2013-02 4 sitesOther conditions: Hormone-Resistant Prostate Cancer, Prostate Adenocarcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate CancerView official trial listing → -
Completed NCT NCT01026792
Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent, Locally Advanced, Metastatic, or Cannot Be Removed By Surgery
Not yet reported National Cancer Institute (NCI) 38 participants Est. completion 2012-11 1 siteOther conditions: Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Recurrent Cervical Carcinoma, Stage IIIA Cervical Cancer, Stage IIIB Cervical Cancer, Stage IVA Cervical Cancer, Stage IVB Cervical CancerView official trial listing → -
Completed NCT NCT01027000
Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported Alliance for Clinical Trials in Oncology 68 participants Est. completion 2023-04 25 sites Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT01028092
mTor-inhibitor (EVERolimus) Based Immunosuppressive Strategies for CNI Minimisation in OLD for Old Renal Transplantation
Not yet reported University Hospital, Brest 327 participants Est. completion 2014-07 18 sitesOther conditions: Renal TransplantView official trial listing → -
Completed NCT NCT01031381
Study of RAD001 and Bevacizumab in Recurrent Ovarian, Peritoneal, and Fallopian Tube Cancer
Not yet reported University of Pittsburgh 50 participants Est. completion 2014-12 1 siteOther conditions: Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal CarcinomaView official trial listing → -
Completed NCT NCT01031446
Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer
Not yet reported, Not yet reported Vanderbilt-Ingram Cancer Center 55 participants Est. completion 2017-08 4 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01031901
Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)
Not yet reported The University of Texas Health Science Center, Houston 52 participants Est. completion 2011-06 1 site Stand-aloneOther conditions: Tuberous Sclerosis, Neurofibromatoses, Angiofibroma, NeurofibromaView official trial listing → -
Withdrawn NCT NCT01033500
Calcineurin Inhibitor-free, Steroid-free Immunosuppressive Regimen in Simultaneous Islet-Kidney Transplantation for Uremic Type 1 Diabetic Patients
Not yet reported University of Wisconsin, Madison Est. completion 2012-12 1 site Stand-aloneOther conditions: Islets of Langerhans Transplantation, Diabetes Mellitus, Type 1, Kidney TransplantationView official trial listing → -
Status unknown NCT NCT01034345
Effect of Rapamycin on Tolerance-related Biomarkers on Stable Liver Transplant Recipients
Not yet reported Hospital Clinic of Barcelona 52 participants Est. completion 2011-11 1 site Stand-aloneOther conditions: Liver TransplantationView official trial listing → -
Status unknown NCT NCT01034371
Comparison of One-stop Hybrid Revascularization Versus Off-pump Coronary Artery Bypass for the Treatment of Multi-vessel Disease
Not yet reported China National Center for Cardiovascular Diseases 400 participants 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01034631
BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma
Not yet reported, Not yet reported Hoosier Cancer Research Network 154 participants Est. completion 2016-12 108 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Status unknown NCT NCT01035034
Comparison of One-stop Hybrid Revascularization Versus Percutaneous Coronary Intervention for the Treatment of Multi-vessel Disease
Not yet reported China National Center for Cardiovascular Diseases 480 participants 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01035229
Global Study Looking at the Combination of RAD001 Plus Best Supportive Care (BSC) and Placebo Plus BSC to Treat Patients With Advanced Hepatocellular Carcinoma.
Not yet reported Novartis Pharmaceuticals 546 participants Est. completion 2013-10 131 sitesOther conditions: CarcinomaView official trial listing → -
Completed NCT NCT01035450
Randomized Evaluation of Sirolimus-eluting Versus Everolimus-eluting Stent Trial
Not yet reported Takeshi Morimoto 3206 participants Est. completion 2014-05 1 siteCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT01038505
Comparison of Tacrolimus and Myfortic Versus Tacrolimus and Sirolimus
Not yet reported University of Miami Est. completion 2013-01Other conditions: Living Donor Kidney Transplants PatientsView official trial listing → -
Terminated NCT NCT01042028
A Randomised Trial With Irinotecan, Cetuximab and Everolimus (ICE)Compared to Capecitabine and Oxaliplatin (CapOx) for Patients With Gemcitabin Resistant Pancreatic Cancer
Not yet reported, Not yet reported Per Pfeiffer 39 participants Est. completion 2014-01 2 sitesOther conditions: Pancreatic CancerView official trial listing → -
Completed NCT NCT01042782
Phase I Study of Daily RAD001 in Combination With Mitomycin C in Patients With Advanced Gastric Cancer or Cancer of the Esophagogastric Junction
Not yet reported Krankenhaus Nordwest 16 participants Est. completion 2012-08 1 siteOther conditions: Advanced Gastric Cancer, Advanced Cancer of the Esophagogastric JunctionView official trial listing → -
Completed NCT NCT01046045
Everolimus Rescue Immunosuppression in the Treatment of Chronic Allograft Dysfunction in Renal Transplant Recipients
Not yet reported Chinese University of Hong Kong 17 participants Est. completion 2013-06 1 siteOther conditions: Chronic Allograft Dysfunction in Renal TransplantationView official trial listing → -
Completed NCT NCT01047293
RAD001, FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma
Not yet reported, Not yet reported University of Utah 47 participants Est. completion 2015-08 2 sitesOther conditions: Colorectal CancerView official trial listing → -
Terminated NCT NCT01048723
Study of RAD001 in Soft Tissue Extremity and/or Retroperitoneal Sarcomas
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 2 participants Est. completion 2011-10 1 siteOther conditions: SarcomaView official trial listing → -
Completed NCT NCT01049620
RAD001 in Combination With Capecitabine and Oxaliplatin (XELOX) in Patients With Advanced Gastric Cancer: RAD001+XELOX
Not yet reported Asan Medical Center 40 participants Est. completion 2013-09 1 siteOther conditions: Advanced Gastric CancerView official trial listing → -
No Longer Available NCT NCT01049633
B-Lymphocyte Immunotherapy in Islet Transplantation for Initial Islet Graft Failure
National Institute of Allergy and Infectious Diseases (NIAID) 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01049841
Perifosine With Temsirolimus for Recurrent Pediatric Solid Tumors
Not yet reported Memorial Sloan Kettering Cancer Center 23 participants Est. completion 2017-03 1 siteOther conditions: Pediatric Solid TumorsView official trial listing → -
Completed NCT NCT01050985
A Study of Temsirolimus Plus Capecitabine in Patients With Advanced Cancer
Not yet reported Georgetown University 47 participants Est. completion 2013-06 1 siteOther conditions: Advanced Solid TumorsView official trial listing → -
Completed NCT NCT01051557
Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma
Not yet reported, Not yet reported National Cancer Institute (NCI) 36 participants Est. completion 2020-09-30 1 siteObstructive sleep apnea Other conditions: Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Adult Diffuse Astrocytoma, Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Mixed Glioma, Adult Oligodendroglioma, Recurrent Adult Brain NeoplasmView official trial listing → -
Completed NCT NCT01051570
Carboplatin, Everolimus, and Prednisone in Treating Patients With Metastatic Prostate Cancer That Progressed After Docetaxel
Not yet reported Barbara Ann Karmanos Cancer Institute 26 participants Est. completion 2013-09 4 sitesOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT01051791
Phase II Study of RAD001 Head and Neck Cancer
Not yet reported Julie E. Bauman, MD, MPH 13 participants Est. completion 2016-08-05 1 siteOther conditions: Squamous Cell Carcinoma of the Head and NeckView official trial listing → -
Completed NCT NCT01054313
Docetaxel and Sirolimus in Patients With Advanced Malignancies
Not yet reported M.D. Anderson Cancer Center 103 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT01055795
Safety Study of Bevacizumab, Everolimus and LBH589 (BEL) for Advanced Solid Tumors
Not yet reported Herbert Hurwitz 14 participants Est. completion 2012-05 1 siteOther conditions: Advanced Solid TumorsView official trial listing → -
Terminated NCT NCT01057277
RAD001, Cisplatin and Concurrent Radiation for Locally Advanced, Inoperable Head and Neck Cancer
Not yet reported howard safran 3 participants Est. completion 2011-06 1 siteOther conditions: Head and Neck CancerView official trial listing → -
Terminated NCT NCT01058408
RAD001 With Weekly Cisplatin and Radiation Therapy in Patients With Locally Advanced Head and Neck Cancer
Not yet reported Dana-Farber Cancer Institute 3 participants 1 siteOther conditions: Head and Neck CancerView official trial listing → -
Completed NCT NCT01058655
RAD001 and AV-951 in Patients With Refractory, Metastatic Colorectal Cancer
Not yet reported, Not yet reported Dana-Farber Cancer Institute 56 participants Est. completion 2015-04 3 sitesOther conditions: Gastrointestinal CancerView official trial listing → -
Completed NCT NCT01059318
A Study to Determine the Safety and Effectiveness of RAD001 (Everolimus) in Patients With Lymphangioleiomyomatosis
Not yet reported Novartis Pharmaceuticals 24 participants Est. completion 2012-06 4 sitesOther conditions: LymphangioleiomyomatosisView official trial listing → -
Completed NCT NCT01060605
Pre Transplant Rapamycin Treatment in Islet Transplantation Alone
Not yet reported IRCCS San Raffaele 11 participants Est. completion 2009-09 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Terminated NCT NCT01061606
Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus
Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2012-10 20 sitesObstructive sleep apnea Other conditions: Recurrent Uterine SarcomaView official trial listing → -
Completed NCT NCT01061788
A Trial of AMG 479, Everolimus (RAD001) and Panitumumab in Patients With Advanced Cancer - QUILT-3.007
Not yet reported Jeffrey Clarke 43 participants Est. completion 2018-12-19 1 siteOther conditions: Advanced Solid Tumors, Non-small Cell Lung CancerView official trial listing → -
Terminated NCT NCT01061853
Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen
Not yet reported University Hospital, Tours 76 participants Est. completion 2012-11 9 sites Stand-aloneOther conditions: Oral Lichen PlanusView official trial listing → -
Completed NCT NCT01062399
Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Not yet reported, Not yet reported Radiation Therapy Oncology Group 279 participants Est. completion 2022-05-20 36 sitesOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT01062555
Calcineurin Inhibitor Sparing After Kidney Transplantation
Not yet reported, Not yet reported University of Minnesota 527 participants Est. completion 2014-04-03 1 siteOther conditions: CNI Side EffectsView official trial listing → -
Terminated NCT NCT01063478
Dose Escalation Study of RAD001 in Combination w/Chemotherapy & Radiation in Patients With NSCLC
Not yet reported University of Chicago 3 participants Est. completion 2012-01 1 siteOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT01065662
AZD2171 and Temsirolimus in Patients With Advanced Gynecological Malignancies
Not yet reported Susana M. Campos, MD 11 participants Est. completion 2021-03 3 sitesOther conditions: Endometrial Cancer, Ovarian Cancer, Cervical Cancer, Fallopian Tube Cancer, Peritoneal CancerView official trial listing → -
Active, not recruiting NCT NCT01068249
Letrozole and RAD001 With Advanced or Recurrent Endometrial Cancer
Not yet reported M.D. Anderson Cancer Center 42 participants Est. completion 2028-04-30 2 sitesOther conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT01070316
Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)
Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 20 participants Est. completion 2016-04 2 sitesOther conditions: Epilepsy, Tuberous Sclerosis ComplexView official trial listing → -
Completed NCT NCT01072890
Temsirolimus and Pazopanib in Patients With Advanced Solid Tumors
Not yet reported University of California, Davis 8 participants Est. completion 2012-02 1 siteOther conditions: Solid TumorsView official trial listing → -
Withdrawn NCT NCT01073111
Assessment of Stent Strut Coverage and Endothelial Function After Drug-Eluting Stents
Not yet reported Hyogo Medical University Est. completion 2017-02 1 siteCardiovascular disease Other conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT01074086
Phase I Study in RAD 001 Patients With Relapse AML
Not yet reported French Innovative Leukemia Organisation 31 participants Est. completion 2012-12 1 siteOther conditions: AMLView official trial listing → -
Completed NCT NCT01075321
Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma
Not yet reported, Not yet reported Mayo Clinic 58 participants Est. completion 2020-02-13 2 sitesObstructive sleep apnea Other conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Hepatosplenic T-cell Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Peripheral T-cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Splenic Marginal Zone Lymphoma, Waldenstrom MacroglobulinemiaView official trial listing → -
Completed NCT NCT01076543
Lenalidomide and Temsirolimus in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 110 participants Est. completion 2018-09-30 11 sitesOther conditions: AIDS-Related Hodgkin Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Follicular Lymphoma, Recurrent Lymphoplasmacytic Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Non-Hodgkin Lymphoma, Recurrent T-Cell Non-Hodgkin Lymphoma, Waldenstrom MacroglobulinemiaView official trial listing → -
Completed NCT NCT01077986
Everolimus, Cetuximab and Capecitabine in Patients With Metastatic Pancreatic Cancer
Not yet reported, Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 35 participants Est. completion 2011-08 1 siteOther conditions: Metastatic Pancreatic CancerView official trial listing → -
Completed NCT NCT01078038
Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-III (LONG-DES-III)
Not yet reported Seung-Jung Park 451 participants Est. completion 2010-08 20 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT01078142
Temsirolimus, Bendamustine and Rituximab for Relapsed Follicular Lymphoma or Mantle Cell Lymphoma
Not yet reported, Not yet reported Georg Hess, MD 39 participants Est. completion 2017-09-08 1 siteOther conditions: Follicular Lymphoma, Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT01079143
Progression of Renal Interstitial Fibrosis / Tubular Atrophy (IF/TA) According to Epithelial-mesenchymal Transition (EMT) and Immunosuppressive Regimen (Everolimus Based Versus CNI Based) in de Novo Renal Transplant Recipients
Not yet reported Novartis Pharmaceuticals 194 participants Est. completion 2012-06 23 sitesOther conditions: Renal Interstitial FibrosisView official trial listing → -
Completed NCT NCT01079286
Study of Nelfinavir and Temsirolimus in Patients With Advanced Cancers
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 18 participants Est. completion 2011-08 1 siteOther conditions: Renal Cell Cancer, CancerView official trial listing → -
Completed NCT NCT01079481
Combination Anticancer Therapy of Paclitaxel and Everolimus for Relapsed or Refractory Small Cell Lung Cancer
Not yet reported Samsung Medical Center 21 participants Est. completion 2013-04 1 siteOther conditions: Small Cell Lung CancerView official trial listing → -
Status unknown NCT NCT01079702
Everolimus and Capecitabine in Patients With Advanced Malignancy
Not yet reported, Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 35 participants Est. completion 2011-01 2 sitesOther conditions: Advanced MalignanciesView official trial listing → -
Terminated NCT NCT01079767
Temsirolimus in Treating Patients With Advanced Liver Cancer and Cirrhosis
Not yet reported Federation Francophone de Cancerologie Digestive 6 participants 1 siteOther conditions: Liver CancerView official trial listing → -
Completed NCT NCT01083368
Temsirolimus and Bevacizumab in Hormone-Resistant Metastatic Prostate Cancer That Did Not Respond to Chemotherapy
Not yet reported, Not yet reported Case Comprehensive Cancer Center 22 participants Est. completion 2014-10 3 sitesOther conditions: Prostate CancerView official trial listing → -
Active, not recruiting NCT NCT01087554
Sirolimus or Everolimus or Temsirolimus and Vorinostat in Advanced Cancer
Not yet reported M.D. Anderson Cancer Center 249 participants Est. completion 2026-08-18 1 site Stand-aloneOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT01087983
Lapatinib With Sirolimus or Metformin
Not yet reported M.D. Anderson Cancer Center 111 participants Est. completion 2015-09 1 site Stand-aloneOther conditions: Advanced CancersView official trial listing → -
Completed NCT NCT01088048
Study to Investigate Idelalisib in Combination With Chemotherapeutic Agents, Immunomodulatory Agents and Anti-CD20 Monoclonal Antibody (mAb) in Participants With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma, Mantle Cell Lymphoma or Chronic Lymphocytic Leukemia
Not yet reported Gilead Sciences 241 participants Est. completion 2015-04-28 11 sitesOther conditions: Indolent Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Mantle Cell LymphomaView official trial listing → -
Status unknown NCT NCT01088893
Everolimus in Breast Cancer Patients After Pre-operative Chemotherapy
Not yet reported Organisation for Oncology and Translational Research 50 participants Est. completion 2013-03 1 siteOther conditions: Breast NeoplasmsView official trial listing → -
Completed NCT NCT01090466
Gemcitabine Hydrochloride, Cisplatin, and Temsirolimus as First-Line Therapy in Treating Patients With Locally Advanced and/or Metastatic Transitional Cell Cancer of the Urothelium
Not yet reported, Not yet reported Cardiff University 15 participants Est. completion 2016-03-16 1 siteOther conditions: Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral CancerView official trial listing → -
Terminated NCT NCT01096199
A Study of TS-1, Cisplatin (CDDP) and RAD001 (Everolimus)
Not yet reported National University Hospital, Singapore 35 participants 1 siteOther conditions: CancerView official trial listing → -
Completed NCT NCT01099527
A Trial of RAD001/Capecitabine in Refractory Gastric Cancer
Not yet reported, Not yet reported Samsung Medical Center 59 participants Est. completion 2013-12 1 siteOther conditions: Metastatic Gastric CancerView official trial listing → -
Terminated NCT NCT01106378
Cynergy: the CYPHER-NEVO Registry
Cordis US Corp. 14000 participants Est. completion 2011-12 3 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT01106833
Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801)
Not yet reported, Not yet reported Medical College of Wisconsin 151 participants Est. completion 2018-06 31 sites Stand-aloneOther conditions: Chronic GVHDView official trial listing → -
Completed NCT NCT01107509
Pilot Study of Neo-Adjuvant Everolimus to Treat Advanced Renal Cell Carcinoma - Analysis of Biomarkers
Not yet reported St. Joseph's Healthcare Hamilton 20 participants Est. completion 2017-10-01 1 siteOther conditions: Carcinoma, Renal CellView official trial listing → -
Completed NCT NCT01108445
Phase II Study of Afinitor vs. Sutent in Patients With Metastatic Non-Clear Cell Renal Cell Carcinoma
Not yet reported Duke University 131 participants Est. completion 2015-04 18 sitesOther conditions: Advanced Non-clear Cell Renal Cell CarcinomaView official trial listing → -
Terminated NCT NCT01111058
Everolimus Versus Placebo in Head and Neck Cancer
Not yet reported University of Chicago 52 participants Est. completion 2018-10 17 sitesOther conditions: Head and Neck CancerView official trial listing → -
Terminated NCT NCT01111448
Temsirolimus in Myelodysplastic Syndrome (MDS)
Not yet reported Technische Universität Dresden 20 participants Est. completion 2014-06 7 sitesOther conditions: Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01111825
Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer
Not yet reported, Not yet reported Puma Biotechnology, Inc. 99 participants Est. completion 2016-07 12 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01114529
Efficacy, Safety and Evolution of Cardiovascular Parameters in Renal Transplant Recipients
Not yet reported Novartis Pharmaceuticals 828 participants Est. completion 2014-10-30 77 sitesOther conditions: Kidney TransplantationView official trial listing → -
Terminated NCT NCT01115803
A Study of LY2584702 With Erlotinib or Everolimus in Participants With Solid Tumors
Not yet reported Eli Lilly and Company 29 participants Est. completion 2011-06 3 sitesOther conditions: Metastases, Neoplasm, Carcinoma, Non-small Cell Lung, Renal Cell Carcinoma, Neuroendocrine TumorsView official trial listing → -
Terminated NCT NCT01116232
Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation
Not yet reported Barbara Ann Karmanos Cancer Institute 4 participants Est. completion 2013-06 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Status unknown NCT NCT01118065
Everolimus in Treating Patients With Progressive or Recurrent, Unresectable, or Metastatic Thyroid Cancer
Not yet reported Leiden University Medical Center 42 participants 1 siteOther conditions: Head and Neck CancerView official trial listing → -
Completed NCT NCT01120028
Campath, Calcineurin Inhibitor Reduction and Chronic Allograft Nephropathy
Not yet reported, Not yet reported University of Oxford 852 participants Est. completion 2020-03 20 sites Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT01120249
S0931, Everolimus in Treating Patients With Kidney Cancer Who Have Undergone Surgery
Not yet reported SWOG Cancer Research Network 1545 participants Est. completion 2025-09-01 1003 sitesOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT01121744
Supralimus-Core™ Pharmacokinetic (PK) Study
Not yet reported Sahajanand Medical Technologies Limited 20 participants Est. completion 2011-01 4 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT01122199
Study of RAD001 + AMG479 for Patients With Advanced Solid Tumors
Not yet reported Shadia Jalal 27 participants Est. completion 2015-01-19 1 siteOther conditions: Neoplasm MetastasesView official trial listing → -
Completed NCT NCT01122615
Sunitinib Plus Temsirolimus in Patients With Renal Cell Cancer (RCC)
Not yet reported M.D. Anderson Cancer Center 23 participants Est. completion 2014-07 1 siteOther conditions: Renal Cell Cancer, Kidney CancerView official trial listing → -
Terminated NCT NCT01125293
Everolimus, Bortezomib and/or Rituximab in Patients With Relapsed/Refractory Waldenstrom's Macroglobulinemia
Not yet reported, Not yet reported Dana-Farber Cancer Institute 46 participants Est. completion 2014-08 1 siteOther conditions: Waldenstrom's MacroglobulinemiaView official trial listing → -
Completed NCT NCT01126333
Long-term Follow-up of Spare the Nephron (STN) Patients
University of Maryland, Baltimore 128 participants Est. completion 2015-06-30 1 siteOther conditions: Kidney TransplantView official trial listing → -
Completed NCT NCT01127763
RAD001 Plus Carboplatin in Breast Cancer Patients
Not yet reported NYU Langone Health 25 participants Est. completion 2013-03 1 siteOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT01133678
Study in Locally Advanced Squamous Cell Carcinoma of Head and Neck
Not yet reported University of Chicago 50 participants Est. completion 2015-01 2 sitesOther conditions: Head and Neck CancerView official trial listing → -
Status unknown NCT NCT01133925
Optical Coherence Tomography in Long Lesions
Not yet reported A.O. Ospedale Papa Giovanni XXIII 22 participants Est. completion 2011-05 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01134952
Study of Sirolimus Versus Mycophenolate Liver Transplant Recipients With Recurrent Hepatitis C Virus (HCV)
Not yet reported London Health Sciences Centre 11 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT01135563
Study of Vinblastine and Sirolimus in Children With Recurrent/Refractory Solid Tumours Including CNS Tumours
Not yet reported The Hospital for Sick Children 14 participants Est. completion 2012-04 5 sites Stand-aloneOther conditions: Solid Tumors, Central Nervous System TumorsView official trial listing → -
Completed NCT NCT01136733
A Study of E7080 Alone, and in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Renal Cell Carcinoma Following One Prior Vascular Endothelial Growth Factor (VEGF)-Targeted Treatment
Not yet reported, Not yet reported Eisai Inc. 173 participants Est. completion 2018-02-08 37 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01139138
Safety Study of the Combination of Panitumumab, Irinotecan and Everolimus in the Treatment of Advanced Colorectal Cancer
Not yet reported, Not yet reported The Queen Elizabeth Hospital 49 participants Est. completion 2017-06 1 siteOther conditions: Colorectal Cancer, Colorectal Carcinoma, Colorectal Tumors, Neoplasms, ColorectalView official trial listing → -
Completed NCT NCT01141244
Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors
Not yet reported National Cancer Institute (NCI) 72 participants 25 sitesOther conditions: Unspecified Childhood Solid Tumor, Protocol SpecificView official trial listing → -
Active, not recruiting NCT NCT01141309
Evaluating the Combination of Everolimus and Sorafenib in the Treatment of Thyroid Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 41 participants Est. completion 2027-06 4 sitesOther conditions: Thyroid CancerView official trial listing → -
Completed NCT NCT01143779
FLT-PET as an Imaging Biomarker With Temsirolimus, Topotecan, and Bortezomib
Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2021-12-27 1 siteOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT01145079
A New Strategy Regarding Discontinuation of Dual Antiplatelet
Not yet reported Yonsei University 982 participants Est. completion 2012-01 1 siteCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT01148628
Dose-finding Study of CAELYXTM and RAD001 in Patients With Advanced Solid Tumors
Not yet reported Southern Europe New Drug Organization 54 participants Est. completion 2011-12 3 sitesOther conditions: Advanced Solid TumorsView official trial listing → -
Terminated NCT NCT01149434
Study of JI-101 in Patients With Advanced Low Grade Endocrine Tumors, Ovarian Cancers or K-RAS Mutant Colon Cancers
Not yet reported, Not yet reported University of Utah 19 participants Est. completion 2012-08 1 siteOther conditions: Cancer, Neuroendocrine, Ovarian Cancer, Colon CancerView official trial listing → -
Completed NCT NCT01150097
Extension Study to Evaluate the Long-term Efficacy and Safety of Everolimus in Liver Transplant Recipients
Not yet reported Novartis Pharmaceuticals 284 participants Est. completion 2013-05-03 57 sitesOther conditions: Liver Transplant RecipientView official trial listing → -
Completed NCT NCT01152801
Safety of RAD001 in Chinese Patients With Metastatic Renal Cell Cancer
Not yet reported Novartis Pharmaceuticals 64 participants Est. completion 2013-12 7 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01152827
RAD001 in Pheochromocytoma or Nonfunctioning Carcinoid
Not yet reported Seoul National University Hospital 33 participants Est. completion 2011-12 1 siteOther conditions: Pheochromocytoma, Extra-adrenal Paraganglioma, Non-functioning CarcinoidView official trial listing → -
Completed NCT NCT01152840
Study of RAD001 in Adenoid Cystic Carcinoma
Not yet reported Seoul National University Hospital 33 participants Est. completion 2012-12 1 siteOther conditions: Adenoid Cystic CarcinomaView official trial listing → -
Completed NCT NCT01154335
Everolimus and OSI-906 for Patients With Refractory Metastatic Colorectal Cancer
Not yet reported SCRI Development Innovations, LLC 18 participants Est. completion 2013-05 2 sitesOther conditions: Metastatic Colorectal CancerView official trial listing → -
Completed NCT NCT01154439
Everolimus MICE-regimen in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 11 participants Est. completion 2015-09-15 5 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT01155258
Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors
Not yet reported University of Southern California 19 participants Est. completion 2014-05 1 siteOther conditions: Extensive Stage Small Cell Lung Cancer, Hereditary Paraganglioma, Male Breast Cancer, Malignant Paraganglioma, Metastatic Gastrointestinal Carcinoid Tumor, Metastatic Pheochromocytoma, Pancreatic Polypeptide Tumor, Recurrent Breast Cancer, Recurrent Cervical Cancer, Recurrent Endometrial Carcinoma, Recurrent Gastrointestinal Carcinoid Tumor, Recurrent Islet Cell Carcinoma, Recurrent Neuroendocrine Carcinoma of the Skin, Recurrent Non-small Cell Lung Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Pheochromocytoma, Recurrent Prostate Cancer, Recurrent Renal Cell Cancer, Recurrent Small Cell Lung Cancer, Recurrent Uterine Sarcoma, Regional Gastrointestinal Carcinoid Tumor, Regional Pheochromocytoma, Stage III Cervical Cancer, Stage III Endometrial Carcinoma, Stage III Neuroendocrine Carcinoma of the Skin, Stage III Ovarian Epithelial Cancer, Stage III Ovarian Germ Cell Tumor, Stage III Prostate Cancer, Stage III Renal Cell Cancer, Stage III Uterine Sarcoma, Stage IIIA Breast Cancer, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Breast Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer, Stage IV Endometrial Carcinoma, Stage IV Neuroendocrine Carcinoma of the Skin, Stage IV Non-small Cell Lung Cancer, Stage IV Ovarian Epithelial Cancer, Stage IV Ovarian Germ Cell Tumor, Stage IV Prostate Cancer, Stage IV Renal Cell Cancer, Stage IV Uterine Sarcoma, Stage IVA Cervical Cancer, Stage IVB Cervical Cancer, Thyroid Gland Medullary CarcinomaView official trial listing → -
Completed NCT NCT01157858
Everolimus and LongActing Octreotide Trial in Polycystic Livers
Not yet reported Radboud University Medical Center 44 participants Est. completion 2012-07 1 siteOther conditions: Polycystic Liver DiseaseView official trial listing → -
Completed NCT NCT01158651
Everolimus for Children With NF1 Chemotherapy-Refractory Radiographic Progressive Low Grade Gliomas
Not yet reported University of Alabama at Birmingham 23 participants Est. completion 2017-10-26 12 sitesOther conditions: GliomaView official trial listing → -
Completed NCT NCT01162551
Trial of Sirolimus and Methotrexate in Relapsed/Refractory Lymphoblastic Leukemia and Lymphoma
Not yet reported Children's Hospital of Philadelphia 5 participants Est. completion 2017-02 1 site Stand-aloneOther conditions: Cancer, Leukemia, LymphomaView official trial listing → -
Completed NCT NCT01163357
Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma
Not yet reported City of Hope Medical Center 18 participants Est. completion 2024-05-20 1 site Stand-aloneOther conditions: Autologous Hematopoietic Stem Cell Transplant Recipient, Loss of Chromosome 17p, Plasma Cell Leukemia, Recurrent Plasma Cell Myeloma, Refractory Plasma Cell MyelomaView official trial listing → -
Withdrawn NCT NCT01163929
A Study to Look at the Combination of Chemotherapy, Trastuzumab and RAD001 in HER2 Positive Breast Cancer
Not yet reported University of Kansas Est. completion 2012-03Other conditions: Breast CancerView official trial listing → -
Completed NCT NCT01164176
Everolimus in Treating Patients With Locally Advanced or Metastatic Thyroid Cancer
Not yet reported Yonsei University 40 participants Est. completion 2014-10 7 sitesOther conditions: Head and Neck CancerView official trial listing → -
Completed NCT NCT01164267
Multicenter Phase II Study to Evaluate the Clinical Activity and the Safety Profile of Everolimus in Marginal Zone B-cell Lymphomas (MZL)
Not yet reported International Extranodal Lymphoma Study Group (IELSG) 30 participants 10 sitesOther conditions: Marginal Zone B-cell LymphomaView official trial listing → -
Terminated NCT NCT01166126
Temsirolimus/AZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IV
Not yet reported National Cancer Institute (NCI) 4 participants Est. completion 2012-06 1 siteObstructive sleep apnea Other conditions: Recurrent Melanoma, Stage IV MelanomaView official trial listing → -
Terminated NCT NCT01166724
Renal Allograft Function and Histology Following Switching From A Tacrolimus to Sirolimus (SRL)-Based Immunosuppression-
Not yet reported The Cleveland Clinic 12 participants Est. completion 2014-12 1 siteOther conditions: Kidney TransplantView official trial listing → -
Completed NCT NCT01167530
Study to Evaluate RAD001 in Combination With Radiotherapy in Non-small Cell Lung Cancer
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 26 participants Est. completion 2017-02-09 1 siteOther conditions: Non-small Cell Lung Cancer, Locally Advanced DiseaseView official trial listing → -
Completed NCT NCT01169701
24 Months Follow-up, Two Arm Study to Compare the Cardiovascular Profile in a Regimen With Everolimus + Mycophenolic Acid (MPA) Versus (vs.) a Regimen of CNI+MPA in Maintenance Renal Transplant Recipients
Not yet reported Novartis Pharmaceuticals 71 participants Est. completion 2014-03 9 sitesOther conditions: Renal TransplantView official trial listing → -
Withdrawn NCT NCT01170052
Bendamustine and Temsirolimus in Patients With Relapsed or Refractory Mantle Cell Non-Hodgkin's Lymphoma (NHL)
Not yet reported, Not yet reported Charite University, Berlin, Germany 20 participants Est. completion 2014-04 3 sitesOther conditions: Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT01172769
Efficacy Study of Temsirolimus to Treat Head and Neck Cancer
Not yet reported Hannover Medical School 42 participants Est. completion 2012-03 7 sitesOther conditions: Head and Neck Squamous Cell CarcinomaView official trial listing → -
Terminated NCT NCT01174199
Temsirolimus and Vorinostat in Treating Patients With Metastatic Prostate Cancer
Not yet reported Roswell Park Cancer Institute 13 participants Est. completion 2016-08 2 sitesOther conditions: Prostate Cancer, Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer, Recurrent Prostate Cancer, Stage IV Prostate CancerView official trial listing → -
Status unknown NCT NCT01175096
Safety and Tolerability Profile of RAD001 Daily in Chinese Patients With Advanced Pulmonary Neuroendocrine Tumor
Not yet reported, Not yet reported Guangdong Provincial People's Hospital 20 participants Est. completion 2012-01 1 siteOther conditions: Neuroendocrine Tumors, Carcinoid TumorView official trial listing → -
Completed NCT NCT01177397
Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma
Not yet reported, Not yet reported Celgene 226 participants Est. completion 2016-12-09 16 sitesOther conditions: Multiple Myeloma, Diffuse Large B-Cell Lymphoma, Glioblastoma Multiforme, Hepatocellular Carcinoma, Non-Small Cell Lung Cancer, Neuroendocrine Tumors of Non-Pancreatic Origin, Hormone Receptor-Positive Breast CancerView official trial listing → -
Withdrawn NCT NCT01178151
Study of Everolimus in the Treatment of Advanced Malignancies in Patients With Peutz-Jeghers Syndrome
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Est. completion 2015-04 2 sitesOther conditions: Peutz-Jeghers Syndrome, Neoplastic Processes, Neoplasm MetastasisView official trial listing → -
Completed NCT NCT01180049
Comparison Of 2 Doses Of Temsirolimus (Torisel) In Patients With Mantle Cell Lymphoma
Not yet reported Pfizer 101 participants Est. completion 2018-06 31 sitesOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT01181271
Tandem Auto-Allo Transplant for Lymphoma
Not yet reported Massachusetts General Hospital 42 participants Est. completion 2016-02 2 sites Stand-aloneOther conditions: Diffuse, Large B-Cell, Lymphoma, Lymphoma, Low-Grade, T-Cell Lymphoma, Mantle-Cell Lymphoma, Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Lymphoma, Small LymphocyticView official trial listing → -
Completed NCT NCT01182168
Gemcitabine and Split-Dose Cisplatin Plus Everolimus (RAD001) in Patients With Advanced Solid Tumor Malignancies
Not yet reported Memorial Sloan Kettering Cancer Center 12 participants Est. completion 2016-03 1 siteOther conditions: Bladder Cancer, Renal Pelvis Cancer, Ureter CancerView official trial listing → -
Completed NCT NCT01182649
Everolimus Stent in Patients With Coronary Artery Disease (CAD)
Not yet reported San Giuseppe Moscati Hospital 600 participants Est. completion 2010-06 1 siteCardiovascular disease Other conditions: Coronary AtherosclerosisView official trial listing → -
Withdrawn NCT NCT01182883
A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors
Not yet reported National Cancer Institute (NCI) Est. completion 2012-04-04Other conditions: Brain Stem Neoplasms, Glioma, PinealomaView official trial listing → -
Completed NCT NCT01183247
An Open, Single Centre, Randomised, Parallel Group Study to Investigate Three Different Immunosuppressive Regimens
Not yet reported University Hospital, Basel, Switzerland 63 participants Est. completion 2010-06 1 siteOther conditions: Comparative Study, Immunosuppressive AgentsView official trial listing → -
Completed NCT NCT01183663
Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)
Not yet reported M.D. Anderson Cancer Center 180 participants Est. completion 2016-05 1 siteOther conditions: Advanced CancersView official trial listing → -
Completed NCT NCT01184326
Expanded Phase I Pazopanib and Everolimus in Advanced Solid Tumors and Previously Treated Advanced Urothelial Cancer
Not yet reported Dana-Farber Cancer Institute 23 participants Est. completion 2017-03 2 sitesOther conditions: Solid Tumor, Kidney CancerView official trial listing → -
Completed NCT NCT01184885
A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 7 participants Est. completion 2013-04 2 sites Stand-aloneOther conditions: Lymphoid Malignancies (New or Relapsed), Acute Lymphoblastic Leukemia, Burkitt Lymphoma, Lymphoblastic Lymphoma, Mantle Cell Lymphoma, Adult T-cell Leukemia/LymphomaView official trial listing → -
Completed NCT NCT01184898
Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 36 participants Est. completion 2016-02 2 sites Stand-aloneOther conditions: AMLView official trial listing → -
Terminated NCT NCT01185366
Everolimus Versus Sunitinib in Non-Clear Cell Renal Cell Carcinoma
Not yet reported M.D. Anderson Cancer Center 73 participants Est. completion 2019-09-09 4 sitesOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT01186094
Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-IV: (LONG-DES-IV)
Not yet reported Seung-Jung Park 502 participants Est. completion 2011-06 12 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT01186107
Comparison of Zotarolimus-Eluting Stent vs Sirolimus-Eluting Stent for Diabetic Patients
Not yet reported Seung-Jung Park 256 participants Est. completion 2013-07 11 sitesCardiovascular disease Other conditions: DiabetesView official trial listing → -
Active, not recruiting NCT NCT01187199
Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer
Not yet reported M.D. Anderson Cancer Center 278 participants Est. completion 2026-04-30 1 siteOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT01188798
Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies
Not yet reported St. Jude Children's Research Hospital 6 participants Est. completion 2012-02 1 siteOther conditions: Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia, Chronic Myelocytic Leukemia, Hodgkin's Disease, Myelodysplastic SyndromeView official trial listing → -
Withdrawn NCT NCT01188889
RAD001 in Patients With Chronic Phase Chronic Myeloid Leukemia w/ Molecular Disease.
Not yet reported, Not yet reported University of Michigan Rogel Cancer Center Est. completion 2017-12 1 siteOther conditions: Chronic Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT01190241
Targeted Therapy Selection Based on Tumor Tissue Kinase Activity Profiles for Patients With Advanced Solid Malignancies, an Exploratory Study
Not yet reported Amsterdam UMC, location VUmc 45 participants Est. completion 2017-12 2 sitesOther conditions: Advanced Solid Tumors, Inoperable, MetastasisView official trial listing → -
Withdrawn NCT NCT01194193
Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours
Not yet reported AstraZeneca 63 participantsOther conditions: Cancer, Advanced Solid Tumours, LymphomasView official trial listing → -
Completed NCT NCT01195194
Selection of Immunosuppression in Kidney Transplant Recipients Depending on Pre-transplant Donor-specific T-cell Reactivity.
Not yet reported Josep M Grinyo 61 participants Est. completion 2013-06 2 sites Stand-aloneOther conditions: Disorder Related to Renal TransplantationView official trial listing → -
Completed NCT NCT01195922
Rapamycin Therapy in Head and Neck Squamous Cell Carcinoma
Not yet reported, Not yet reported National Institute of Dental and Craniofacial Research (NIDCR) 37 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: Mouth Neoplasms, Head and Neck Neoplasms, Tongue Neoplasms, Carcinoma, Squamous CellView official trial listing → -
Completed NCT NCT01196429
Temsirolimus, Carboplatin, and Paclitaxel as First-Line Therapy in Treating Patients With Newly Diagnosed Stage III-IV Clear Cell Ovarian Cancer
Not yet reported National Cancer Institute (NCI) 90 participants Est. completion 2015-01 145 sitesOther conditions: Ovarian Clear Cell Cystadenocarcinoma, Stage III Ovarian Cancer, Stage IV Ovarian CancerView official trial listing → -
Completed NCT NCT01196819
Randomized MicroPort's Firehawk DES Versus Xience V: TARGET I Trial
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 458 participants Est. completion 2016-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01197170
Hormone Receptor Positive Disease Across Solid Tumor Types: A Phase I Study of Single-Agent Hormone Blockade and Combination Approaches With Targeted Agents to Provide Synergy and Overcome Resistance
Not yet reported M.D. Anderson Cancer Center 277 participants Est. completion 2021-01-13 1 siteOther conditions: Solid Tumors, Advanced CancerView official trial listing → -
Terminated NCT NCT01198158
Everolimus With or Without Bevacizumab in Treating Patients With Advanced Kidney Cancer That Progressed After First-Line Therapy
Not yet reported National Cancer Institute (NCI) 77 participants Est. completion 2017-12-16 524 sitesOther conditions: Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v7, Stage IV Renal Cell Cancer AJCC v7View official trial listing → -
Completed NCT NCT01198184
Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 and Temsirolimus in Treating Patients With Advanced Solid Tumors
Not yet reported National Cancer Institute (NCI) 18 participants Est. completion 2013-10 2 sitesOther conditions: Endometrial Papillary Serous Carcinoma, Recurrent Endometrial Carcinoma, Recurrent Renal Cell Cancer, Stage III Endometrial Carcinoma, Stage III Renal Cell Cancer, Stage IV Endometrial Carcinoma, Stage IV Renal Cell Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT01198665
RAD001 Combined With CHOP in Newly Diagnosed Peripheral T-cell Lymphomas
Not yet reported, Not yet reported Samsung Medical Center 46 participants Est. completion 2014-12 5 sitesOther conditions: Peripheral T Cell Lymphoma Unspecified, Anaplastic Large Cell Lymphoma, ALK-negative, Angioimmunoblastic T Cell Lymphoma, Cutaneous T Cell LymphomaView official trial listing → -
Completed NCT NCT01200693
Z-SEA-SIDE: Sirolimus Versus Everolimus Versus Zotarolimus-eluting Stent Assessment in Bifurcated Lesions and Clinical SIgnificance of Residual siDE-branch Stenosis
Not yet reported Catholic University of the Sacred Heart 80 participants Est. completion 2012-03 1 siteCardiovascular disease Other conditions: Coronary StenosisView official trial listing → -
Completed NCT NCT01201369
A Study to Examine the Implantation Characteristics of Two Drug-Eluting Stents
Not yet reported Royal Brompton & Harefield NHS Foundation Trust 40 participants Est. completion 2011-07 1 siteCardiovascular diseaseView official trial listing → -
Terminated NCT NCT01202058
An Observational Safety Evaluation of Patients Treated With the NEVO™ Sirolimus-eluting Coronary Stent. (NEVO II)
Not yet reported Cordis US Corp. 156 participants Est. completion 2012-10 3 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01203722
Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies
Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 87 participants Est. completion 2024-05-28 1 siteOther conditions: Hematologic MalignanciesView official trial listing → -
Terminated NCT NCT01204450
Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma
Not yet reported UNC Lineberger Comprehensive Cancer Center 7 participants Est. completion 2013-03 2 sitesOther conditions: Brain and Central Nervous System Tumors, Neuroblastoma, Sarcoma, Unspecified Childhood Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT01204476
Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma
Not yet reported National Cancer Institute (NCI) 27 participants 1 siteOther conditions: Gastrin-Producing Neuroendocrine Tumor, Lung Carcinoid Tumor, Metastatic Digestive System Neuroendocrine Tumor G1, Pancreatic Glucagonoma, Pancreatic Insulinoma, Pancreatic Polypeptide Tumor, Paraganglioma, Recurrent Digestive System Neuroendocrine Tumor G1, Recurrent Merkel Cell Carcinoma, Recurrent Pancreatic Neuroendocrine Carcinoma, Regional Digestive System Neuroendocrine Tumor G1, Somatostatin-Producing Neuroendocrine Tumor, Stage III Merkel Cell Carcinoma, Stage IV Merkel Cell Carcinoma, Thyroid Gland Medullary CarcinomaView official trial listing → -
Completed NCT NCT01206036
CESAR Study in Prostate Cancer With Temsirolimus Added to Standard Docetaxel Therapy (CEPTAS)
Not yet reported, Not yet reported Central European Society for Anticancer Drug Research 19 participants Est. completion 2015-10 2 sitesOther conditions: Prostatic NeoplasmsView official trial listing → -
Completed NCT NCT01206140
Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery
Not yet reported National Cancer Institute (NCI) 70 participants Est. completion 2015-04 8 sitesOther conditions: Recurrent Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue SarcomaView official trial listing → -
Completed NCT NCT01206764
A Trial of Everolimis in Patients With Advanced Renal Cell Carcinoma.
Not yet reported Novartis Pharmaceuticals 143 participants Est. completion 2017-07-01 22 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01210482
Temsirolimus (Torisel) Drug Use Investigation (Regulatory Post Marketing Commitment Plan)
Pfizer 1050 participants Est. completion 2018-05-31 1 siteOther conditions: Renal Cell CarcinomaView official trial listing → -
Terminated NCT NCT01213394
Mycophenolate Mofetil for Reducing Cardiovascular Risk in Renal Transplant Recipients
Not yet reported Ramesh Prasad 2 participants Est. completion 2011-12 1 site Stand-aloneCardiovascular disease Other conditions: Kidney TransplantationView official trial listing → -
Terminated NCT NCT01215136
First-line Everolimus +/- Paclitaxel for Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma
Not yet reported Matthew Galsky 36 participants Est. completion 2018-04-24 11 sitesOther conditions: Transitional Cell Carcinoma, Bladder Carcinoma, Urothelial CarcinomaView official trial listing → -
Status unknown NCT NCT01216826
Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Osteosarcoma
Not yet reported Sidnei Epelman 20 participants Est. completion 2014-12 1 siteObstructive sleep apneaView official trial listing → -
Status unknown NCT NCT01216839
Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Rhabdomyosarcoma and Other Soft Tissue Sarcomas
Not yet reported Sidnei Epelman 20 participants Est. completion 2013-12 1 siteOther conditions: Refractory or Relapsed RMS and Soft Tissue SarcomasView official trial listing → -
Completed NCT NCT01217125
Rapamycin In Angiomyolipomas In Patients With Tuberous Sclerosis
Not yet reported Fundacio Puigvert 18 participants Est. completion 2011-05Other conditions: AngiomyolipomaView official trial listing → -
Completed NCT NCT01217177
A Study of mTOR Inhibitor Everolimus (RAD001) in Association With Cisplatin and Radiotherapy for Locally Advanced Cervix Cancer
Not yet reported Novartis Pharmaceuticals 14 participants Est. completion 2014-04 2 sitesOther conditions: Locally Advanced Cervical CancerView official trial listing → -
Active, not recruiting NCT NCT01217931
Sequential Two-agent Assessment in Renal Cell Carcinoma Therapy: The START Trial
Not yet reported M.D. Anderson Cancer Center 180 participants Est. completion 2028-01-31 1 siteOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT01218555
Study of Everolimus (RAD001) in Combination With Lenalidomide
Not yet reported Emory University 44 participants Est. completion 2020-11-05 2 sitesOther conditions: Solid Organ Malignancies, Adenoidcystic Carcinoma, Neuroendocrine TumorsView official trial listing → -
Terminated NCT NCT01220297
Sirolimus & Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related Donor HCT
Not yet reported Stanford University 3 participants Est. completion 2011-08 1 site Stand-aloneOther conditions: Hematologic Diseases, Acute-graft-versus-host Disease, Leukemia, Non-Hodgkin Lymphoma (NHL), Hodgkin LymphomaView official trial listing → -
Completed NCT NCT01220856
Reparixin in Pancreatic Islet Transplantation
Not yet reported Dompé Farmaceutici S.p.A 9 participants Est. completion 2013-04-30 2 sitesOther conditions: Pancreatic Islet Transplantation in Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01222715
Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma
Not yet reported National Cancer Institute (NCI) 87 participants Est. completion 2015-06 184 sitesObstructive sleep apnea Other conditions: Recurrent Adult Soft Tissue SarcomaView official trial listing → -
Completed NCT NCT01223027
Study of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell Carcinoma
Not yet reported Novartis Pharmaceuticals 564 participants Est. completion 2014-06 199 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Terminated NCT NCT01223755
Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency
Not yet reported, Not yet reported Mario Negri Institute for Pharmacological Research 41 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)View official trial listing → -
Suspended NCT NCT01226056
Sorafenib in Combination With RAD001 in Advanced Solid Tumors Selected on Molecular Targets
Not yet reported, Not yet reported Southern Europe New Drug Organization 45 participants Est. completion 2012-12 1 siteOther conditions: Advanced Solid TumorsView official trial listing → -
Status unknown NCT NCT01226355
NOYA CoCr Biodegradable Coating Sirolimus-Eluting Coronary Stent System
Not yet reported Medfavour (Beijing) Medical Co., Ltd 300 participants Est. completion 2014-11 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01229943
Everolimus and Octreotide Acetate With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Neuroendocrine Tumors That Cannot Be Removed by Surgery
Not yet reported National Cancer Institute (NCI) 150 participants Est. completion 2018-01-03 394 sitesOther conditions: Advanced Pancreatic Neuroendocrine Tumor, Locally Advanced Pancreatic Neuroendocrine Tumor, Pancreatic Gastrinoma, Pancreatic Neuroendocrine Tumor G1, Pancreatic Neuroendocrine Tumor G2, Pancreatic VipomaView official trial listing → -
Completed NCT NCT01231399
Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer
Not yet reported, Not yet reported City of Hope Medical Center 6 participants Est. completion 2016-07 3 sitesOther conditions: Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction, Diffuse Adenocarcinoma of the Stomach, Intestinal Adenocarcinoma of the Stomach, Mixed Adenocarcinoma of the Stomach, Recurrent Esophageal Cancer, Recurrent Gastric Cancer, Stage IV Esophageal Cancer, Stage IV Gastric CancerView official trial listing → -
Completed NCT NCT01231412
Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant
Not yet reported Fred Hutchinson Cancer Center 174 participants Est. completion 2017-06-30 11 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Aggressive Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma, Hematopoietic and Lymphoid Cell Neoplasm, Indolent Non-Hodgkin Lymphoma, Mantle Cell Lymphoma, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Plasma Cell Myeloma, Refractory Chronic Lymphocytic Leukemia, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Hodgkin Lymphoma, Small Lymphocytic Lymphoma, T-Cell Chronic Lymphocytic Leukemia, Waldenstrom MacroglobulinemiaView official trial listing → -
Completed NCT NCT01231659
Safety and Efficacy of RAD001 (Everolimus) in Combination With Letrozole in the Treatment of Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer
Not yet reported Novartis Pharmaceuticals 72 participants Est. completion 2017-04-30 7 sitesOther conditions: Postmenopausal Women, Locally Advanced Metastatic Breast Cancer, Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT01233167
Effect of Different Anti-platelet Strategies on the Long-term Outcome After Sirolimus Drug-eluting Stent Implantation
Not yet reported Sir Run Run Shaw Hospital 5232 participants Est. completion 2013-05Cardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT01234974
IGF-1 Inhibitor Pasireotide Lar in Combination With the m-TOR Inhibitor Everolimus
Not yet reported Milton S. Hershey Medical Center Est. completion 2013-12 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT01236378
Study To Evaluate Pharmacokinetics Of Sirolimus In Stable Renal Transplant Recipients
Not yet reported Pfizer 24 participants Est. completion 2011-04 2 sites Stand-aloneOther conditions: Transplant Rejection, Renal TransplantationView official trial listing → -
Terminated NCT NCT01239342
Akt Inhibitor MK2206 or Everolimus in Treating Patients With Refractory Kidney Cancer
Not yet reported National Cancer Institute (NCI) 43 participants Est. completion 2018-09-19 8 sitesOther conditions: Metastatic Kidney Carcinoma, Recurrent Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v7, Stage IV Renal Cell Cancer AJCC v7View official trial listing → -
Terminated NCT NCT01239368
Th1/Tc1 Immunotherapy Following Stem Cell Transplantation in Multiple Myeloma
Not yet reported, Not yet reported National Cancer Institute (NCI) 34 participants Est. completion 2017-08-16 2 sitesOther conditions: Myeloma, Plasma-Cell, Myeloma-Multiple, MyelomatosisView official trial listing → -
Completed NCT NCT01239472
Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant
Not yet reported Andre Barreto Pereira 30 participants Est. completion 2015-06 1 siteOther conditions: Renal Transplant Rejection, ImmunosuppressionView official trial listing → -
Completed NCT NCT01242306
Comparison of Endothelial Dysfunction (BMS vs SES) in the Same Patient With Multiple Coronary Artery Lesions
Not yet reported, Not yet reported Azienda Ospedaliera San Camillo Forlanini 25 participants Est. completion 2009-12 1 siteOther conditions: Endothelial DysfunctionView official trial listing → -
Completed NCT NCT01242631
Everolimus for Patients With Relapsed/Refractory Germ Cell Cancer
Not yet reported Hannover Medical School 25 participants Est. completion 2014-03 8 sitesOther conditions: Testicular Cancer, Germ Cell CancerView official trial listing → -
Completed NCT NCT01244906
Post-transplant Cyclophosphamide and Sirolimus Following Reduced Intensity Conditioning (RIC) Transplant
Not yet reported Northside Hospital, Inc. 26 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Hematologic NeoplasmsView official trial listing → -
Status unknown NCT NCT01246817
Temsirolimus-RCC-imaging
Not yet reported Radboud University Medical Center 51 participants 1 siteOther conditions: Renal Cell CancerView official trial listing → -
Completed NCT NCT01247428
First-In-Human Trial of the MiStent Drug-Eluting Stent (DES) in Coronary Artery Disease
Not yet reported Micell Technologies 30 participants Est. completion 2016-03 5 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01248403
A Randomized, Double Blind Study Evaluating Paclitaxel With and Without RAD001 in Patients With Gastric Carcinoma After Prior Chemotherapy
Not yet reported Krankenhaus Nordwest 300 participants Est. completion 2019-10 1 siteOther conditions: Advanced Gastric Cancer, Esophagogastric Junction CancerView official trial listing → -
Completed NCT NCT01248494
PhIb BKM120 or BEZ235+Endocrine Treatment in Post-Menopausal Patients With Hormone Receptor + Metastatic Breast Cancer
Not yet reported Vanderbilt-Ingram Cancer Center 72 participants Est. completion 2016-05 6 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT01251458
Hepatocellular Carcinoma (HCC)_Torisel_
Not yet reported, Not yet reported Chinese University of Hong Kong 46 participants Est. completion 2016-01 1 siteOther conditions: Inoperable HCCView official trial listing → -
Completed NCT NCT01251575
Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant
Not yet reported Fred Hutchinson Cancer Center 77 participants Est. completion 2019-02-11 5 sites Stand-aloneOther conditions: Adult Acute Lymphoblastic Leukemia, Adult Acute Myeloid Leukemia, Adult Diffuse Large B-Cell Lymphoma, Adult Myelodysplastic Syndrome, Adult Non-Hodgkin Lymphoma, Aggressive Non-Hodgkin Lymphoma, Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia, Childhood Diffuse Large B-Cell Lymphoma, Childhood Myelodysplastic Syndrome, Childhood Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia in Remission, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid Cell Neoplasm, Mantle Cell Lymphoma, Plasma Cell Myeloma, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, T-Cell Prolymphocytic Leukemia, Waldenstrom Macroglobulinemia, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Hodgkin LymphomaView official trial listing → -
Completed NCT NCT01252251
RAD001 (Everolimus) and Pasireotide (SOM230) LAR in Patients With Advanced Uveal Melanoma
Not yet reported Memorial Sloan Kettering Cancer Center 14 participants Est. completion 2016-06 1 siteOther conditions: Uveal MelanomaView official trial listing → -
Status unknown NCT NCT01255956
Restenosis Treatment With Rapamycin Eluting Stent or Paclitaxel Eluting Balloon Catheter (RESTENOZA)
Not yet reported Medical University of Warsaw 200 participants Est. completion 2012-07 4 sitesOther conditions: In-Stent RestenosisView official trial listing → -
Completed NCT NCT01256385
Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous Therapy
Not yet reported National Cancer Institute (NCI) 86 participants Est. completion 2013-12 24 sitesOther conditions: Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Laryngeal Verrucous Carcinoma, Recurrent Lip and Oral Cavity Squamous Cell Carcinoma, Recurrent Metastatic Squamous Cell Carcinoma in the Neck With Occult Primary, Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma, Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma, Recurrent Oral Cavity Verrucous Carcinoma, Recurrent Oropharyngeal Squamous Cell Carcinoma, Recurrent Salivary Gland Carcinoma, Salivary Gland Squamous Cell Carcinoma, Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary, Stage IV Hypopharyngeal Squamous Cell Carcinoma, Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma, Stage IVA Laryngeal Squamous Cell Carcinoma, Stage IVA Laryngeal Verrucous Carcinoma, Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma, Stage IVA Major Salivary Gland Carcinoma, Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma, Stage IVA Oral Cavity Verrucous Carcinoma, Stage IVA Oropharyngeal Squamous Cell Carcinoma, Stage IVB Laryngeal Squamous Cell Carcinoma, Stage IVB Laryngeal Verrucous Carcinoma, Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma, Stage IVB Major Salivary Gland Carcinoma, Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma, Stage IVB Oral Cavity Verrucous Carcinoma, Stage IVB Oropharyngeal Squamous Cell Carcinoma, Stage IVC Laryngeal Squamous Cell Carcinoma, Stage IVC Laryngeal Verrucous Carcinoma, Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma, Stage IVC Major Salivary Gland Carcinoma, Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma, Stage IVC Oral Cavity Verrucous Carcinoma, Stage IVC Oropharyngeal Squamous Cell Carcinoma, Tongue CarcinomaView official trial listing → -
Status unknown NCT NCT01257373
Efficacy and Safety of Firebird 2 Stent in Treatment of Complex Coronary Lesions in Diabetes
Xijing Hospital 1300 participants Est. completion 2013-04 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01259063
RAD001 and Intravesical Gemcitabine in BCG-Refractory Primary or Secondary Carcinoma In Situ of the Bladder
Not yet reported, Not yet reported Memorial Sloan Kettering Cancer Center 33 participants Est. completion 2017-06 1 siteOther conditions: Bladder CancerView official trial listing → -
Status unknown NCT NCT01260558
Test of Long-Term Safety and Efficacy of Sirolimus-Permanent-Polymer Eluting Stent (Cypher)- and Sirolimus-Polymer-free Eluting Stents (PPS/PFS) Assessed by Optical Coherence Tomography
Not yet reported Deutsches Herzzentrum Muenchen 20 participants Est. completion 2012-12 2 sitesOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT01262703
Safety Study of a Bioresorbable Coronary Stent
Not yet reported REVA Medical, Inc. 49 participants Est. completion 2018-12 1 site Stand-aloneCardiovascular disease Other conditions: Myocardial Ischemia, Coronary Artery Stenosis, Coronary Disease, Coronary RestenosisView official trial listing → -
Completed NCT NCT01263353
Safety and Tolerability of Pasireotide LAR in Combination With Everolimus in Advanced Metastatic NETs
Not yet reported Novartis Pharmaceuticals 36 participants Est. completion 2014-03 4 sitesOther conditions: Gastroenteropancreatic Neuroendocrine Tumor of the Pulmonary ot Gastroenteropancreatic SystemView official trial listing → -
Status unknown NCT NCT01263951
Study of Everolimus and Sorafenib in Patients With Advanced Thyroid Cancer Who Progressed on Sorafenib Alone
Not yet reported Thomas Jefferson University 35 participants Est. completion 2022-05 1 siteOther conditions: Differentiated Thyroid CancerView official trial listing → -
Terminated NCT NCT01264341
Efficacy and Safety of Bevacizumab/Temsirolimus Combination to Treat Advanced Renal Cell Carcinoma
Not yet reported Hellenic Cooperative Oncology Group 39 participants Est. completion 2015-07 8 sitesOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT01265030
A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis
Not yet reported, Not yet reported MaineHealth 9 participants Est. completion 2021-12-22 8 sites Stand-aloneOther conditions: Desmoid TumorView official trial listing → -
Completed NCT NCT01266057
Sirolimus or Vorinostat and Hydroxychloroquine in Advanced Cancer
Not yet reported M.D. Anderson Cancer Center 143 participants Est. completion 2021-02-11 1 site Stand-aloneOther conditions: Advanced CancersView official trial listing → -
Completed NCT NCT01266148
SCHEDULE - Scandinavian Heart Transplant Everolimus de Novo Study With Early Calcineurin Inhibitor (CNI) Avoidance
Not yet reported Novartis Pharmaceuticals 115 participants Est. completion 2012-12 6 sitesOther conditions: Renal Function and Chronic Allograft VasculopathyView official trial listing → -
Status unknown NCT NCT01266239
Comparison Between Everolimus-eluting Stent (EES) and Sirolimus-eluting Stent (SES) in the Bifurcation Lesion
Not yet reported Shin Yukuhashi Hospital 300 participants Est. completion 2015-07 5 sitesOther conditions: Ischemic Heart DiseaseView official trial listing → -
Completed NCT NCT01266837
Open Label, Single Arm Trial to Characterize Patients With Metastatic RCC Treated With Everolimus After Failure of the First VEGF-targeted Therapy (MARC-2)
Not yet reported iOMEDICO AG 64 participants Est. completion 2017-10-31 8 sitesOther conditions: Metastatic Renal Cell Carcinoma, Failure of Exactly One Prior VEGF-targeted TherapyView official trial listing → -
Status unknown NCT NCT01268371
Comparison of Biolimus-eluting Biodegradable Polymer, Everolimus-eluting and Sirolimus-eluting Coronary Stents
Not yet reported Ajou University School of Medicine 1462 participants Est. completion 2015-07 26 sitesCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT01269684
Immediate Conversion From Tacrolimus to Everolimus in Stable Maintenance Renal Transplant Recipients
Not yet reported Novartis Pharmaceuticals Est. completion 2008-08 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT01270321
Pasireotide & Everolimus in Adult Patients With Radioiodine-Refractory Differentiated & Medullary Thyroid Cancer
Not yet reported Emory University 42 participants Est. completion 2019-02 3 sitesOther conditions: Thyroid CancerView official trial listing → -
Terminated NCT NCT01272141
A Study of Lapatinib in Combination With Everolimus in Patients With Advanced, Triple Negative Breast Cancer
Not yet reported Emory University 5 participants Est. completion 2014-01 3 sitesOther conditions: Breast Neoplasms, Breast Cancer, Cancer of the BreastView official trial listing → -
Completed NCT NCT01274234
OCT Evaluation of Healing of COMBO Stent
Not yet reported, Not yet reported Prof. Stephen Lee 61 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: Coronary Restenosis, Coronary ThrombosisView official trial listing → -
Completed NCT NCT01275222
Everolimus in Combination With Imatinib in Patients With Glivec Refractory/Resistant Gastrointestinal Stromal Tumors
Not yet reported, Not yet reported Novartis Pharmaceuticals 117 participants Est. completion 2008-09-03 16 sitesOther conditions: Gastrointestinal Stromal TumorsView official trial listing → -
Terminated NCT NCT01276834
Comparison of Immunosuppression on Progression of Arteriosclerosis in Renal Transplantation
Not yet reported Dianet Dialysis Centers 13 participants Est. completion 2012-07 1 siteOther conditions: Renal TransplantationView official trial listing → -
Withdrawn NCT NCT01280669
Intravitreal Sirolimus as Therapeutic Approach to Uveitis
Not yet reported Stanford University Est. completion 2024-12 1 site Stand-aloneOther conditions: Uveitis, Intermediate Uveitis, Posterior Uveitis, PanuveitisView official trial listing → -
Completed NCT NCT01281514
A Study of Carboplatin, PLD and Everolimus in Certain Gynecologic Cancer
Not yet reported Fox Chase Cancer Center 21 participants Est. completion 2018-01-08 1 siteOther conditions: Fallopian Tube Cancer, Peritoneal Cavity Cancer, Recurrent Ovarian Epithelial CancerView official trial listing → -
Completed NCT NCT01281865
Everolimus in Combination With Imatinib Mesylate in Treating Patients With Locally Advanced, Locally Recurrent, or Metastatic Soft Tissue Sarcoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 14 participants Est. completion 2013-10 1 siteOther conditions: Adult Synovial Sarcoma, Recurrent Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue SarcomaView official trial listing → -
Completed NCT NCT01281917
Study of Velcade and Temsirolimus for Relapsed or Refractory Non-Hodgkin Lymphoma
Not yet reported University of Wisconsin, Madison 40 participants Est. completion 2014-06 18 sitesOther conditions: Non-Hodgkins LymphomaView official trial listing → -
Withdrawn NCT NCT01281943
Study of Pegylated Liposomal Doxorubicin and Temsirolimus in Patients With Advanced Hepatocellular Cancer
Not yet reported Washington University School of Medicine Est. completion 2014-05Other conditions: Liver NeoplasmsView official trial listing → -
Completed NCT NCT01282697
Clinical Trial of Rapamycin and Irinotecan in Pediatric Patients With Refractory Solid Tumors
Not yet reported University Hospital, Strasbourg, France 42 participants Est. completion 2013-02-20 9 sitesOther conditions: Refractory Solid Tumors in ChildrenView official trial listing → -
Completed NCT NCT01283334
A Study of Carboplatin, Cetuximab and RAD001 in Advanced Head and Neck Cancer
Not yet reported, Not yet reported Emory University 20 participants Est. completion 2014-11 1 siteOther conditions: Head and Neck Neoplasms, Cancer of the Head and NeckView official trial listing → -
Status unknown NCT NCT01283789
Lapatinib and RAD-001 for HER2 Positive Metastatic Breast Cancer
Not yet reported University of Kansas Medical Center 23 participants Est. completion 2017-04 1 siteOther conditions: Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT01289301
Studying the Effect of Changing Immunosuppression in Case of Polyoma BK Virus Infection of the Renal Transplant
Not yet reported Hannover Medical School 124 participants Est. completion 2018-10 4 sitesOther conditions: Disorder Related to Renal Transplantation, Immunosuppression Related Infectious Disease, Virus DiseasesView official trial listing → -
Completed NCT NCT01289912
Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC)
Not yet reported Mustafa Sahin 52 participants Est. completion 2014-12 2 sitesOther conditions: Tuberous Sclerosis ComplexView official trial listing → -
Completed NCT NCT01294748
Clinical Investigation of the MiStent Drug Eluting Stent (DES) in Coronary Artery Disease
Not yet reported Micell Technologies 184 participants Est. completion 2016-08 28 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01298713
Tamoxifen-RAD001 Versus Tamoxifen Alone in Patients With Anti-aromatase Resistant Breast Metastatic Cancer
Not yet reported ARCAGY/ GINECO GROUP 111 participants Est. completion 2018-09-12 1 siteOther conditions: Breast Neoplasms, mTor ProteinView official trial listing → -
Terminated NCT NCT01303965
Allo Transplant Followed by Lenalidomide and Sirolimus Maintenance in High-Risk Multiple Myeloma (MM)
Not yet reported, Not yet reported Sherif S. Farag 14 participants Est. completion 2017-07-28 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Withdrawn NCT NCT01305395
Strategies To Prevent Cardiac Allograft Vasculopathy Related Events in Heart Transplant Recipients
Not yet reported University of Minnesota Est. completion 2015-01 1 site Stand-aloneOther conditions: Cardiac Allograft VasculopathyView official trial listing → -
Completed NCT NCT01305941
A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain Metastases
Not yet reported UNC Lineberger Comprehensive Cancer Center 32 participants Est. completion 2017-10-16 4 sitesOther conditions: HER-2 Positive Breast CancerView official trial listing → -
No Longer Available NCT NCT01309022
Immunosuppressive Medications for Participants in ITN005CT (NCT00014911)
National Institute of Allergy and Infectious Diseases (NIAID) 3 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Terminated NCT NCT01312064
De Novo Everolimus-based Therapy for Renal Transplantation Using Rituximab Induction
Not yet reported National Taiwan University Hospital 2 participants Est. completion 2012-04 1 siteOther conditions: Renal InsufficiencyView official trial listing → -
Terminated NCT NCT01313390
Everolimus and Docetaxel in Treating Patients With Recurrent, Locally Advanced, or Metastatic Head and Neck Cancer
Not yet reported, Not yet reported University College, London 4 participants Est. completion 2011-04 1 siteOther conditions: Head and Neck CancerView official trial listing → -
Terminated NCT NCT01313559
Pasireotide (SOM230) With or Without Everolimus in Treating Patients With Hormone Resistant, Chemotherapy Naive Prostate Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 6 participants Est. completion 2012-11-29 2 sitesOther conditions: Castrate Resistant Prostate Cancer, Chemotherapy Naive Prostate Cancer, Prostate CancerView official trial listing → -
Terminated NCT NCT01313923
Evaluating Sirolimus to Treat Autoimmune Blistering Dermatosis Pemphigus
Not yet reported University of California, Irvine 3 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: PemphigusView official trial listing → -
Completed NCT NCT01316809
AZD8055 for Adults With Recurrent Gliomas
Not yet reported National Cancer Institute (NCI) 22 participants Est. completion 2016-04-04 1 siteOther conditions: Glioblastoma Multiforme, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Malignant Glioma, Brainstem GliomaView official trial listing → -
Completed NCT NCT01317615
RAD001 With Paclitaxel and Carboplatin in First Line Treatment of Patients With Advanced Large Cell Lung Cancer With Neuroendocrine Differentiation
Not yet reported Novartis Pharmaceuticals 49 participants Est. completion 2015-03 9 sitesOther conditions: Carcinoma, Large Cell, Neuroendocrine TumorsView official trial listing → -
Terminated NCT NCT01318915
Research Study of ATG and Rituximab in Renal Transplantation
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 10 participants Est. completion 2017-08-25 6 sites Stand-aloneOther conditions: Renal Transplant RecipientsView official trial listing → -
Completed NCT NCT01324492
Safety and Efficacy of RAD001 in Chinese Patients With Advanced Pulmonary Neuroendocrine Tumor
Not yet reported Novartis Pharmaceuticals 16 participants Est. completion 2014-06 4 sitesOther conditions: Lung Neuroendocrine NeoplasmView official trial listing → -
Withdrawn NCT NCT01326468
Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University Est. completion 2016-12Other conditions: Head and Neck CancerView official trial listing → -
Withdrawn NCT NCT01328730
The Real-world Firebird 2 Versus Cypher Sirolimus-eluting Stent in Treating Patients With Coronary Artery Disease
Not yet reported Shanghai Jiao Tong University School of Medicine 430 participants Est. completion 2013-06 1 siteOther conditions: Coronary Artery StenosisView official trial listing → -
Completed NCT NCT01331135
Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors
Not yet reported Emory University 18 participants Est. completion 2017-08-09 1 site Stand-aloneObstructive sleep apnea Other conditions: Ewing's Sarcoma, Astrocytoma, Atypical Teratoid/Rhabdoid Tumor, Ependymoma, Germ Cell Tumor, Glioma, Medulloblastoma, Rhabdoid Tumor, Retinoblastoma, Clear Cell Sarcoma, Renal Cell Carcinoma, Wilms Tumor, Hepatoblastoma, NeuroblastomaView official trial listing → -
Withdrawn NCT NCT01332279
Everolimus, Erlotinib Hydrochloride, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer Previously Treated With Radiation Therapy
Not yet reported Fox Chase Cancer Center Est. completion 2011-05 1 siteOther conditions: Recurrent Metastatic Squamous Neck Cancer With Occult Primary, Recurrent Salivary Gland Cancer, Recurrent Squamous Cell Carcinoma of the Hypopharynx, Recurrent Squamous Cell Carcinoma of the Larynx, Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity, Recurrent Squamous Cell Carcinoma of the Oropharynx, Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Recurrent Verrucous Carcinoma of the Larynx, Recurrent Verrucous Carcinoma of the Oral Cavity, Salivary Gland Squamous Cell Carcinoma, Tongue CancerView official trial listing → -
Completed NCT NCT01333085
Everolimus, Carboplatin, and Paclitaxel in Locally Advanced Head and Neck Cancer That Cannot Be Removed by Surgery
Not yet reported, Not yet reported GERCOR - Multidisciplinary Oncology Cooperative Group 49 participants Est. completion 2013-05 5 sitesOther conditions: Head and Neck CancerView official trial listing → -
Completed NCT NCT01334073
Study of the Combination of Axitinib Plus Everolimus in Patients With Malignant Advanced Solid Tumors
Not yet reported University Hospital, Bordeaux 19 participants Est. completion 2015-01 2 sitesOther conditions: Malignant Advanced Solid Tumors, Carcinoma, Renal CellView official trial listing → -
Completed NCT NCT01334502
Everolimus, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Untreated Diffuse Large B-Cell Lymphoma
Not yet reported Alliance for Clinical Trials in Oncology 26 participants Est. completion 2017-08 1 siteOther conditions: LymphomaView official trial listing → -
Withdrawn NCT NCT01335074
Temsirolimus + Sorafenib in Advanced Hepatocellular Carcinoma (HCC)
Not yet reported, Not yet reported Philipps University Marburg 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT01337765
Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor Patients
Not yet reported Pfizer 29 participants Est. completion 2013-03-22 6 sitesOther conditions: Unspecified Adult Solid Tumor, Protocol Specific, Solid TumorView official trial listing → -
Completed NCT NCT01338090
89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors
University Medical Center Groningen 14 participants Est. completion 2012-03 1 siteOther conditions: Neuroendocrine TumorsView official trial listing → -
Status unknown NCT NCT01341834
Safety and Tolerability Study of RAD001 and LBH589 in All Solid Tumors With Enrichment for EBV Driven Tumors
Not yet reported National Cancer Centre, Singapore 49 participants Est. completion 2018-12 1 siteOther conditions: Nasopharyngeal Carcinoma, Lymphomas, Any EBV+ Solid TumourView official trial listing → -
Completed NCT NCT01343498
Study of PI3 Kinase/mTOR Inhibitor BEZ235 Twice Daily for Advanced Solid Tumors
Not yet reported SCRI Development Innovations, LLC 33 participants Est. completion 2014-01 2 sitesOther conditions: Malignant Solid TumourView official trial listing → -
Terminated NCT NCT01345136
Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma
Not yet reported Jonsson Comprehensive Cancer Center 4 participants Est. completion 2024-02-06 1 siteOther conditions: Neurofibromatosis Type 2, Neuroma, AcousticView official trial listing → -
Completed NCT NCT01346085
Calcineurin Inhibitor (CNI)-Free Immunosuppressive Regimen in T1D Patients Receiving Islet Transplantation
Not yet reported, Not yet reported Ospedale San Raffaele 10 participants Est. completion 2012-06 2 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Terminated NCT NCT01347866
Clinical Study Of PI3K/mTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced Cancer
Not yet reported Pfizer 105 participants Est. completion 2015-12 18 sitesOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT01349296
BIBF 1120 and RAD001 in Solid Tumors - Phase I
Not yet reported University of Cologne 18 participants Est. completion 2016-05 1 siteOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT01353625
Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.
Not yet reported Celgene 118 participants Est. completion 2021-03-12 17 sitesObstructive sleep apnea Other conditions: Glioblastoma Multiforme, Squamous Cell Carcinoma of Head and Neck, Prostate Cancer, Chronic Lymphocytic Leukemia, Neoplasm MetastasisView official trial listing → -
Completed NCT NCT01354301
Efficacy and Safety of Induction Strategies Combined With Low Tacrolimus Exposure in Kidney Transplant Recipients Receiving Everolimus or Sodium Mycophenolate
Not yet reported Hospital do Rim e Hipertensão 300 participants Est. completion 2014-12 1 siteOther conditions: Cytomegalovirus Infection, Renal Transplant Failure, Transplant; Complication, RejectionView official trial listing → -
Completed NCT NCT01358266
Study Assessing Double-masked Uveitis Treatment
Not yet reported Santen Inc. 592 participants Est. completion 2016-12 151 sitesOther conditions: Uveitis; Posterior, DisorderView official trial listing → -
Completed NCT NCT01363752
A Study Looking at Kidney Function in Kidney Transplant Recipients Who Are Taking Anti-rejection Medication Including Tacrolimus and With or Without Sirolimus.
Not yet reported Astellas Pharma Inc 853 participants Est. completion 2013-09-18 58 sites Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT01364844
Safety and Tolerability of DS-7423 in Subjects With Advanced Solid Malignant Tumors
Not yet reported Daiichi Sankyo 42 participants Est. completion 2013-11 3 sitesOther conditions: Solid Tumor, Colorectal Cancer, Endometrial CancerView official trial listing → -
Terminated NCT NCT01365468
Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1)
Not yet reported Novartis Pharmaceuticals 9 participants Est. completion 2015-04 2 sitesOther conditions: Plexiform Neurofibroma Associated With Neurofibromatosis Type 1View official trial listing → -
Completed NCT NCT01367457
INHIBITOR: Retrospective Study Of Patients With Renal Cell Carcinoma And Mantle Cell Lymphoma Treated With Temsirolimus
Pfizer 243 participants Est. completion 2015-04 16 sitesOther conditions: Carcinoma, Renal Cell, Lymphoma, Mantle-CellView official trial listing → -
Completed NCT NCT01368627
The E-SERIES Registry for Supralimus® Coronary Stent for the Treatment of Unselected Patients With Coronary Lesions
Not yet reported Sahajanand Medical Technologies Limited 1274 participants Est. completion 2011-12 7 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT01369433
A Rollover Protocol to Allow Continued Access to Tivozanib (AV 951) for Subjects Enrolled in Other Tivozanib Protocols
Not yet reported AVEO Pharmaceuticals, Inc. 225 participants Est. completion 2015-10 49 sitesOther conditions: Solid TumorsView official trial listing → -
Status unknown NCT NCT01373632
Firebird 2 Versus Excel Sirolimus-eluting Stent in Treating Real-world Patients With Coronary Artery Disease
Not yet reported Shanghai Jiao Tong University School of Medicine 570 participants Est. completion 2013-09 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT01374451
Efficacy of Everolimus Alone or in Combination With Pasireotide LAR in Advanced PNET
Not yet reported Novartis Pharmaceuticals 160 participants Est. completion 2015-02 47 sitesOther conditions: Islet Cell TumorView official trial listing → -
Completed NCT NCT01374750
Efficacy of Sirolimus In Liver Transplantation for Hepatocellular Carcinoma (HCC)
Not yet reported Seoul National University Hospital 45 participants Est. completion 2016-05 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT01375296
China Made Sirolimus Eluting Stent for Intermediate Lesion
Not yet reported, Not yet reported Shanghai Jiao Tong University School of Medicine 600 participants Est. completion 2011-11 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT01375829
Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Not yet reported National Cancer Institute (NCI) 22 participants Est. completion 2027-03-19 2 sitesOther conditions: Adult Solid NeoplasmView official trial listing → -
Terminated NCT NCT01376310
GSK1120212 Rollover Study
Not yet reported Novartis Pharmaceuticals 159 participants Est. completion 2018-01-18 19 sitesOther conditions: CancerView official trial listing → -
Terminated NCT NCT01378377
Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus
Not yet reported EMD Serono 33 participants Est. completion 2012-02-23 3 sitesOther conditions: Advanced Solid TumorView official trial listing → -
Completed NCT NCT01379209
Intravenous Administration of RGI-2001 in Patient Undergoing Allogenic Hematopoietic Stem Cell Transplantation (AHSCT)
Not yet reported, Not yet reported Regimmune Corporation 68 participants Est. completion 2017-04 6 sites Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Terminated NCT NCT01379521
Safety and Efficacy of RAD001 + TACE in Localized Unresectable HCC
Not yet reported Novartis Pharmaceuticals 65 participants Est. completion 2015-06 5 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT01381692
Bortezomib, Rituximab, and Dexamethasone With or Without Temsirolimus in Treating Patients With Untreated or Relapsed Waldenstrom Macroglobulinemia or Relapsed or Refractory Mantle Cell or Follicular Lymphoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 9 participants Est. completion 2021-09-01 11 sitesOther conditions: Recurrent Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Non-Hodgkin Lymphoma, Recurrent Small Lymphocytic Lymphoma, Recurrent Waldenstrom Macroglobulinemia, Refractory Follicular Lymphoma, Refractory Mantle Cell Lymphoma, Refractory Marginal Zone Lymphoma, Refractory Non-Hodgkin Lymphoma, Refractory Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT01382043
Angiographic and IVUS Follow-up After Simultaneously Implanted Different Drug-eluting Stents in Same Individuals (AIFSIDDES)
Liuhuaqiao Hospital 48 participants Est. completion 2011-01 1 siteOther conditions: Percutaneous Coronary AngioplastyView official trial listing → -
Withdrawn NCT NCT01383668
Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung Cancer
Not yet reported Mayo Clinic Est. completion 2013-02-08 Stand-aloneOther conditions: Recurrent Non-small Cell Lung Cancer, Squamous Cell Lung Cancer, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT01387880
Irinotecan, Cetuximab and Everolimus to Patients With Metastatic Colorectal Cancer
Not yet reported Herlev Hospital 100 participants Est. completion 2012-03 1 siteOther conditions: Metastatic Colorectal CancerView official trial listing → -
Completed NCT NCT01389427
Escalating Doses of Torisel in Combination With Three Chemotherapies Regimens: R-CHOP, R-FC or R-DHA for Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL).
Not yet reported, Not yet reported The Lymphoma Academic Research Organisation 41 participants Est. completion 2015-09 11 sitesOther conditions: Mantle Cell Lymphoma RefractoryView official trial listing → -
Completed NCT NCT01390519
A Norwegian Observational Trial Evaluating the Treatment of Advanced Renal Cell Cancer Patients Under Treatment of Afinitor
Novartis Pharmaceuticals 30 participants Est. completion 2015-12 3 sitesOther conditions: Metastatic Renal Cell Carcinoma (mRCC)View official trial listing → -
Completed NCT NCT01390818
Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors
Not yet reported EMD Serono 146 participants Est. completion 2015-04 8 sitesOther conditions: Locally Advanced Solid Tumor, Metastatic Solid Tumor, Breast Cancer, Non Small Cell Lung Cancer, Melanoma, Colorectal CancerView official trial listing → -
Completed NCT NCT01392183
Pazopanib Versus Temsirolimus in Poor-Risk Clear-Cell Renal Cell Carcinoma (RCC)
Not yet reported M.D. Anderson Cancer Center 69 participants Est. completion 2019-09-08 1 siteOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT01396200
Cyclophosphamide and Pulse Dexamethasone With Rapamycin or Hydroxychloroquine
Not yet reported Abramson Cancer Center at Penn Medicine 6 participants Est. completion 2012-10 1 siteOther conditions: MyelomaView official trial listing → -
Active, not recruiting NCT NCT01396408
A Phase II Study of Sunitinib or Temsirolimus in Patients With Advanced Rare Tumours
Not yet reported Canadian Cancer Trials Group 137 participants Est. completion 2026-12-31 17 sitesOther conditions: Advanced Rare TumoursView official trial listing → -
Completed NCT NCT01398306
Biomarkers for Angiogenesis in Renal Cell Carcinoma and Neuro-endocrine Tumours.
University Medical Center Groningen 40 participants Est. completion 2012-04 1 siteOther conditions: Carcinoma, Carcinoma, Renal Cell, Neuroendocrine Tumors, Carcinoid Tumor, Pancreatic Islet Cell TumorsView official trial listing → -
Status unknown NCT NCT01399242
Efficacy of Certican® in Combination With Myfortic® in Renal
Not yet reported Hospital Universitário São José 40 participants Est. completion 2013-06 1 siteOther conditions: Disorder Related to Renal TransplantationView official trial listing → -
Completed NCT NCT01399918
Everolimus and Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma (RCC)
Not yet reported Memorial Sloan Kettering Cancer Center 57 participants Est. completion 2020-12-28 7 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01403415
Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma
Not yet reported National Cancer Institute (NCI) 13 participants 31 sitesOther conditions: Childhood B Acute Lymphoblastic Leukemia, Childhood T Acute Lymphoblastic Leukemia, Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT01404104
Neo-adjuvant Temsirolimus in Patients With Advanced Renal Cell Carcinoma
Not yet reported St. Joseph's Healthcare Hamilton 11 participants Est. completion 2014-08 1 siteOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01404325
Efficacy Regarding Renal Function of Everolimus in Combination With Specific Standard Immunosuppressive Regimen Lung Transplant Recipients
Not yet reported Novartis Pharmaceuticals 130 participants Est. completion 2017-01-05 9 sitesOther conditions: Lung TransplantationView official trial listing → -
Completed NCT NCT01405287
Study of Vascular Healing With the Combo Stent Versus the Everolimus Eluting Stent in ACS Patients by Means of OCT
Not yet reported OrbusNeich 60 participants Est. completion 2014-01 6 sitesCardiovascular disease Other conditions: Atherosclerosis, Acute Coronary Syndrome (ACS)View official trial listing → -
Completed NCT NCT01408004
Rotating Pazopanib and Everolimus to Avoid Resistance
Not yet reported Netherlands Working Group on Immunotherapy of Oncology 101 participants Est. completion 2014-04 17 sitesOther conditions: Clear Cell Renal CarcinomaView official trial listing → -
Completed NCT NCT01410448
Everolimus in de Novo Kidney Transplant Recipients
Not yet reported Novartis Pharmaceuticals 383 participants Est. completion 2015-12 22 sitesOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT01412164
Observational Registry Study: FIREHAWK DES for Treating Coronary Artery Disease (CAD)
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 730 participants Est. completion 2017-01 1 siteCardiovascular diseaseView official trial listing → -
Terminated NCT NCT01412515
A Phase II Study With Tumor Molecular Pharmacodynamic (MPD) Evaluation of Oral mTOR-inhibitor Everolimus (RAD001) 10 mg Daily in Patients Suffering From Classic or Endemic Kaposi's Sarcoma
Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 11 participants Est. completion 2011-05 1 siteOther conditions: Kaposi SarcomaView official trial listing → -
Completed NCT NCT01412892
Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas
Not yet reported Assistance Publique - Hôpitaux de Paris 30 participants Est. completion 2014-10 1 siteOther conditions: Neurofibromatosis Type 1, Plexiform Neurofibroma, NeurofibromatosesView official trial listing → -
Completed NCT NCT01417065
Temsirolimus In Phase 0
Not yet reported M.D. Anderson Cancer Center 15 participants 1 siteOther conditions: Advanced CancerView official trial listing → -
Status unknown NCT NCT01418794
Efficacy and Safety of the YUKON Drug Eluting Stent in Diffuse Coronary Artery Disease
Not yet reported Shenyang Northern Hospital 606 participants 4 sitesOther conditions: Acute Coronary SyndromesView official trial listing → -
Completed NCT NCT01419639
Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2
Not yet reported NYU Langone Health 10 participants Est. completion 2013-12 1 siteOther conditions: Neurofibromatosis Type IIView official trial listing → -
Terminated NCT NCT01420081
A Study Of Two Dual PI3K/mTOR Inhibitors, PF-04691502 And PF-05212384 In Patients With Recurrent Endometrial Cancer
Not yet reported Pfizer 67 participants Est. completion 2015-12-25 51 sitesOther conditions: Endometrial NeoplasmsView official trial listing → -
Status unknown NCT NCT01423708
Everolimus in de Novo Liver Transplantation: a Multicentre Randomized Study
Not yet reported Azienda Ospedaliera di Padova 117 participants Est. completion 2014-01 7 sitesOther conditions: Liver Failure, Liver Diseases, Liver Cirrhosis, Liver NeoplasmsView official trial listing → -
Completed NCT NCT01427946
Phase 1b/2 Study of Retaspimycin HCl (IPI-504) in Combination With Everolimus in KRAS Mutant Non-small Cell Lung Cancer
Not yet reported, Not yet reported Infinity Pharmaceuticals, Inc. 47 participants Est. completion 2014-10 5 sitesOther conditions: Non-small Cell Lung CancerView official trial listing → -
Status unknown NCT NCT01428973
Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis Regimens
Not yet reported University of Liege 200 participants Est. completion 2024-12 13 sites Stand-aloneOther conditions: Graft-Versus-Host Disease, Hematological MalignanciesView official trial listing → -
Completed NCT NCT01430572
Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients
Not yet reported M.D. Anderson Cancer Center 62 participants Est. completion 2020-05-12 1 siteOther conditions: Advanced Cancers, Solid TumorsView official trial listing → -
Completed NCT NCT01434602
Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas
Not yet reported, Not yet reported National Cancer Institute (NCI) 86 participants Est. completion 2021-07-13 1 siteOther conditions: Brain Tumor, Glioblastoma, Anaplastic GliomaView official trial listing → -
Completed NCT NCT01442090
Study of GDC-0980 Versus Everolimus in Participants With Metastatic Renal Cell Carcinoma Who Have Progressed on or Following Vascular Endothelial Growth Factor- (VEGF) Targeted Therapy
Not yet reported Genentech, Inc. 85 participants Est. completion 2015-07 22 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01443104
Sirolimus-eluting Stents With Biodegradable Polymer Versus an Everolimus-eluting Stents
Not yet reported Insel Gruppe AG, University Hospital Bern 2119 participants Est. completion 2018-06 9 sitesCardiovascular disease Other conditions: Angina PectorisView official trial listing → -
Terminated NCT NCT01443754
Hybrid Revascularisation by Combined Coronary Artery Bypass Graft (CABG) and PCI in Multivessel Coronary Disease
Ettore Sansavini Health Science Foundation 50 participants Est. completion 2016-04 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01445106
A Phase I Trial of Nelfinavir (Viracept ) in Adults With Solid Tumors
Not yet reported National Cancer Institute (NCI) 28 participants Est. completion 2011-05-09 1 siteOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT01445548
Sirolimus for Advanced Age-Related Macular Degeneration
Not yet reported, Not yet reported National Eye Institute (NEI) 6 participants Est. completion 2014-02 1 site Stand-aloneOther conditions: Age-Related Macular Degeneration, Geographic AtrophyView official trial listing → -
Status unknown NCT NCT01446484
Treatment of Children With Kidney Transplants by Injection of CD4+CD25+FoxP3+ T Cells to Prevent Organ Rejection
Not yet reported, Not yet reported Pirogov Russian National Research Medical University 30 participants Est. completion 2014-11 2 sites Stand-aloneOther conditions: End-Stage Renal Disease, Kidney FailureView official trial listing → -
Completed NCT NCT01451879
Observational Study for Subjects With Pompe Disease Undergoing Immune Modulation Therapies
University of Florida 11 participants Est. completion 2017-10 1 siteOther conditions: Pompe DiseaseView official trial listing → -
Terminated NCT NCT01453140
In-vivo Regulatory T Cell Enhancement With Cyclophosphamide and Sirolimus
Not yet reported, Not yet reported Hackensack Meridian Health 3 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT01453504
Everolimus in Combination With DHAP in Patients With Relapsed or Refractory Hodgkin Lymphoma
Not yet reported, Not yet reported University of Cologne 73 participants Est. completion 2019-03 1 siteOther conditions: Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT01455649
Study to Evaluate the Safety and Efficacy of Switching Calcineurin Inhibitor to Everolimus After Kidney Transplantation in Adults
Not yet reported Deise de Boni Monteiro de Carvalho 30 participants Est. completion 2013-11 1 siteOther conditions: Kidney Transplant, ImmunosuppressionView official trial listing → -
Completed NCT NCT01460420
Sequential Trial on Reduced Intensity Conditioning (RIC) Allogeneic Transplantation
Not yet reported, Not yet reported European Myeloma Network B.V. 49 participants Est. completion 2017-06-29 10 sites Stand-aloneOther conditions: Hematologic Malignancies, Multiple MyelomaView official trial listing → -
Completed NCT NCT01460979
Efficacy,Tolerability,Safety of Temsirolimus in Women With Platinum-refractory Ovarian Carcinoma or Advanced Endometrial Carcinoma
Not yet reported AGO Study Group 47 participants Est. completion 2015-11 18 sitesOther conditions: Genital Diseases, Female, Ovarian Diseases, Ovarian Neoplasms, Endometrial NeoplasmsView official trial listing → -
Completed NCT NCT01462006
Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis (IPF)
Not yet reported University of Virginia 32 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: Idiopathic Pulmonary Fibrosis, Diffuse Parenchymal Lung Disease, Interstitial Lung DiseaseView official trial listing → -
Completed NCT NCT01462214
Study of Everolimus and Low-dose Cyclophosphamide in Patients With Metastatic Renal Cell Cancer
Not yet reported, Not yet reported Hans J. van der Vliet, MD, PhD 96 participants Est. completion 2017-01 13 sitesOther conditions: Metastatic Renal Cell CancerView official trial listing → -
Completed NCT NCT01466231
Everolimus in Refractory Testicular Germ Cell Cancer
Not yet reported National Cancer Institute, Slovakia 15 participants Est. completion 2015-06 1 siteOther conditions: Germ Cell TumorView official trial listing → -
Completed NCT NCT01467986
Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma
Not yet reported University of Regensburg 130 participants Est. completion 2020-09-30 1 siteOther conditions: Neuroblastoma RecurrentView official trial listing → -
Completed NCT NCT01469572
Pasireotide, Everolimus and Selective Internal Radioembolization Therapy for Unresectable Hepatic Metastases
Not yet reported Emory University 13 participants Est. completion 2018-10 1 siteOther conditions: Neuroendocrine TumorsView official trial listing → -
Completed NCT NCT01469884
Effect of Switching to Certican® in Viremia of Hepatitis C Virus in Adult Renal Allograft Recipients
Not yet reported Irmandade Santa Casa de Misericórdia de Porto Alegre 30 participants Est. completion 2015-04 1 siteOther conditions: Renal Allograft, Hepatitis CView official trial listing → -
Completed NCT NCT01470209
A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies
Not yet reported Emory University 43 participants Est. completion 2017-05 1 siteOther conditions: Solid Tumors, Lung CancerView official trial listing → -
Completed NCT NCT01472705
Everolimus- Versus Biolimus-Eluting Stents in All-Comers
University of Freiburg 814 participants Est. completion 2011-11 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01473095
Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma
Not yet reported ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 120 participants Est. completion 2017-08-07 7 sitesOther conditions: Solid Tumor, Malignant Lymphoma, TumorView official trial listing → -
Terminated NCT NCT01473732
Mechanisms and Treatment of Chronic Allograft Injury (CAI) Due to Calcineurin Inhibitor (CNI) Toxicity
Not yet reported Montefiore Medical Center 2 participants Est. completion 2012-08 1 siteOther conditions: Chronic Allograft Injury, Calcineurin Inhibitor ToxicityView official trial listing → -
Completed NCT NCT01482156
Dose Finding Study of RAD001 (Everolimus, Afinitor®) in Combination With BEZ235 in Patients With Advanced Solid Tumors
Not yet reported Novartis Pharmaceuticals 46 participants Est. completion 2015-02 10 sitesOther conditions: Advanced Solid Tumors, Metastatic Breast Cancer, Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01482299
RAD001 in Advanced Gastric Cancer Who Failed Standard First-line Treatment With pS6 Ser 240/4 Expression
Not yet reported Asan Medical Center 45 participants Est. completion 2014-01 1 siteOther conditions: Stomach NeoplasmView official trial listing → -
Terminated NCT NCT01488253
Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell Transplants
Not yet reported The Korean Society of Blood and Marrow Transplantation 3 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: Acute Leukemia in Remission, Myelodysplastic Syndromes, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Accelerated-PhaseView official trial listing → -
Completed NCT NCT01488487
Everolimus and Pasireotide (SOM230) in Patients With Advanced or Metastatic Hepatocellular Carcinoma
Not yet reported UNC Lineberger Comprehensive Cancer Center 24 participants Est. completion 2015-03 3 sitesOther conditions: Advanced Adult Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT01490476
Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) Patients
Not yet reported Assistance Publique - Hôpitaux de Paris 10 participants Est. completion 2017-01 1 siteOther conditions: Neurofibromatosis 2View official trial listing → -
Completed NCT NCT01490749
Trial of XELOX Followed by Radiation Combined With Carboplatin and RAD001 for Esophageal Cancer
Not yet reported Emory University 17 participants Est. completion 2019-02 3 sitesOther conditions: Esophageal Cancer, Neoplasms, EsophagealView official trial listing → -
Completed NCT NCT01491672
Everolimus as Second-line Therapy in Metastatic Renal Cell Carcinoma
Not yet reported Novartis Pharmaceuticals 134 participants Est. completion 2015-05 17 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Withdrawn NCT NCT01492894
Kidney Allograft Dysfunction Without Reversible Causes
Not yet reported University of Minnesota Est. completion 2011-10 1 siteOther conditions: Kidney Graft DysfunctionView official trial listing → -
Terminated NCT NCT01495247
Phase Ib/II Trial of BEZ235 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer
Not yet reported, Not yet reported Novartis Pharmaceuticals 18 participants Est. completion 2014-05-19 3 sitesOther conditions: Inoperable Locally Advanced Breast Cancer, Metastatic Breast Cancer (MBC)View official trial listing → -
Terminated NCT NCT01499160
Letrozole and Lapatinib Followed by Everolimus in Women With Advanced Breast Cancer
Not yet reported University of Maryland, Baltimore 7 participants Est. completion 2016-12 1 siteOther conditions: Breast Neoplasms, Endocrine Breast Diseases, Neoplasm MetastasisView official trial listing → -
Completed NCT NCT01502904
Neointimal Coverage After Implantation of Biolimus Eluting Stent With Biodegradable Polymer: Optical Coherence Tomographic Assessment According to the Treatment of Dyslipidemia and Hypertension and the Types of Implanted Drug-eluting Stents
Not yet reported Yonsei University 120 participants Est. completion 2015-06 1 siteOther conditions: Stable Angina or Acute Coronary Syndrome Considered for Percutaneous Coronary Intervention With Dyslipidemia or HypertensionView official trial listing → -
Completed NCT NCT01507519
Study Safety and Performance of the Biomime Stent in Patients With Single, De Novo, Non-Complex Coronary Lesions
Not yet reported Meril Life Sciences Pvt. Ltd. 30 participants Est. completion 2011-03 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT01508104
Safety Study of BEZ235 With Everolimus in Subjects With Advanced Solid Tumors
Not yet reported University of Cincinnati 19 participants Est. completion 2014-12 1 siteOther conditions: CancerView official trial listing → -
Completed NCT NCT01509560
PhaseII,Open-label,Pilot Study Evaluating the Safety+Efficacy of Certican ® in the Prevention of Chronic Graft-versus-host Disease+Late Pulmonary Complications After Allogeneic Hematopoietic Cell Transplantation Blood
Not yet reported Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH 21 participants Est. completion 2016-04-30 1 siteOther conditions: Condition After Allogenic Peripheral Stem Cell Transplantation (SCT)View official trial listing → -
Completed NCT NCT01510119
Autophagy Inhibition to Augment Mammilian Target of Rapamycin (mTOR) Inhibition: A Phase I/II Trial of RAD001 and Hydroxychloroquine (HCQ) in Patients With Previously Treated Renal Cell Carcinoma
Not yet reported, Not yet reported Abramson Cancer Center at Penn Medicine 40 participants Est. completion 2017-01-05 3 sitesOther conditions: Metastatic Clear Cell Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01514110
Gastric Cancer RAD001 Study
Not yet reported, Not yet reported Chinese University of Hong Kong 35 participants Est. completion 2019-03-06 1 siteOther conditions: Gastric CancerView official trial listing → -
Completed NCT NCT01514448
Safety and Efficacy of Everolimus in Metastatic Renal Cell Carcinoma After Failure of First Line Therapy With Sunitinib or Pazopanib
Not yet reported Novartis Pharmaceuticals 29 participants Est. completion 2016-04-01 13 sitesOther conditions: Metastatic Renal Cell Carcinoma (mRCC)View official trial listing → -
Completed NCT NCT01516723
Hybrid Sirolimus-eluting Versus Everolimus-eluting Stents for Total Coronary Occlusions
Not yet reported R&D Cardiologie 330 participants Est. completion 2020-12-31 4 sites Stand-aloneCardiovascular disease Other conditions: Coronary Disease, Coronary StenosisView official trial listing → -
Completed NCT NCT01517074
Sirolimus Injections for Autoimmune Scleritis
Not yet reported, Not yet reported National Eye Institute (NEI) 5 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: ScleritisView official trial listing → -
Completed NCT NCT01517243
Phase II Study of Alternating Sunitinib and Temsirolimus
Not yet reported Dartmouth-Hitchcock Medical Center 37 participants Est. completion 2018-08-20 2 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01520103
Study to Compare Vinorelbine In Combination With the mTOR Inhibitor Everolimus vs. Vinorelbin Monotherapy for Second-line Treatment in Advanced Breast Cancer
Not yet reported AIO-Studien-gGmbH 139 participants Est. completion 2016-10-31 1 siteOther conditions: Her2-negative Metastatic Breast Cancer, Her2-negative Locally Advanced Breast CancerView official trial listing → -
Completed NCT NCT01522820
Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors
Not yet reported Roswell Park Cancer Institute 18 participants Est. completion 2016-07 1 site Stand-aloneOther conditions: Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma, Estrogen Receptor Negative, Estrogen Receptor Positive, Glioblastoma, Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma, Metastatic Renal Cell Cancer, Recurrent Adult Brain Neoplasm, Recurrent Bladder Carcinoma, Recurrent Breast Carcinoma, Recurrent Colorectal Carcinoma, Recurrent Esophageal Carcinoma, Recurrent Gastric Carcinoma, Recurrent Hepatocellular Carcinoma, Recurrent Lung Carcinoma, Recurrent Melanoma, Recurrent Ovarian Carcinoma, Recurrent Prostate Carcinoma, Recurrent Renal Cell Carcinoma, Recurrent Uterine Corpus Carcinoma, Resectable Hepatocellular Carcinoma, Sarcoma, Stage IA Breast Cancer, Stage IA Ovarian Cancer, Stage IA Uterine Corpus Cancer, Stage IB Breast Cancer, Stage IB Ovarian Cancer, Stage IB Uterine Corpus Cancer, Stage IC Ovarian Cancer, Stage II Uterine Corpus Cancer, Stage IIA Breast Cancer, Stage IIA Lung Carcinoma, Stage IIA Ovarian Cancer, Stage IIB Breast Cancer, Stage IIB Esophageal Cancer, Stage IIB Lung Carcinoma, Stage IIB Ovarian Cancer, Stage IIB Skin Melanoma, Stage IIC Ovarian Cancer, Stage IIC Skin Melanoma, Stage IIIA Breast Cancer, Stage IIIA Esophageal Cancer, Stage IIIA Lung Carcinoma, Stage IIIA Ovarian Cancer, Stage IIIA Skin Melanoma, Stage IIIA Uterine Corpus Cancer, Stage IIIB Breast Cancer, Stage IIIB Esophageal Cancer, Stage IIIB Ovarian Cancer, Stage IIIB Skin Melanoma, Stage IIIB Uterine Corpus Cancer, Stage IIIC Breast Cancer, Stage IIIC Esophageal Cancer, Stage IIIC Ovarian Cancer, Stage IIIC Skin Melanoma, Stage IIIC Uterine Corpus Cancer, Stage IV Bladder Urothelial Carcinoma, Stage IV Esophageal Cancer, Stage IV Ovarian Cancer, Stage IV Prostate Cancer, Stage IV Skin Melanoma, Stage IVA Uterine Corpus Cancer, Stage IVB Uterine Corpus CancerView official trial listing → -
Completed NCT NCT01523977
Everolimus With Multiagent Re-Induction Chemotherapy in Pediatric Patients With ALL
Not yet reported Dana-Farber Cancer Institute 22 participants Est. completion 2018-11 8 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01524783
Everolimus Plus Best Supportive Care vs Placebo Plus Best Supportive Care in the Treatment of Patients With Advanced Neuroendocrine Tumors (GI or Lung Origin)
Not yet reported Novartis Pharmaceuticals 302 participants Est. completion 2020-08-07 97 sitesOther conditions: Advanced NET of GI Origin, Advanced NET of Lung Origin, Neuroendocrine TumorsView official trial listing → -
Status unknown NCT NCT01525719
Single Arm Study of RAD001 as Monotherapy in Treatment in Advanced Cholangiocarcinoma
Not yet reported Ratchavithi Hospital 40 participants Est. completion 2014-06Other conditions: CholangiocarcinomaView official trial listing → -
Completed NCT NCT01526356
Topical Rapamycin to Erase Angiofibromas in TSC
Not yet reported The University of Texas Health Science Center, Houston 179 participants Est. completion 2014-08 10 sitesOther conditions: Angiofibromas, Tuberous SclerosisView official trial listing → -
Completed NCT NCT01529138
Study of Axitinib and Temsirolimus in Solid Tumors
Not yet reported Emory University 13 participants Est. completion 2014-03 1 site Stand-aloneOther conditions: CancerView official trial listing → -
Completed NCT NCT01529554
Controlled Level EVERolimus in Acute Coronary Syndromes
Not yet reported, Not yet reported University of Zurich 150 participants Est. completion 2021-11-29 8 sitesOther conditions: Acute Coronary SyndromesView official trial listing → -
Terminated NCT NCT01529593
Temsirolimus in Combination With Metformin in Patients With Advanced Cancers
Not yet reported M.D. Anderson Cancer Center 34 participants Est. completion 2025-03-14 1 siteOther conditions: Advanced CancersView official trial listing → -
Terminated NCT NCT01534143
High Dose Busulfan and Bortezomib in Treating Patients With High Risk Multiple Myeloma Undergoing Stem Cell Transplant
Not yet reported Barbara Ann Karmanos Cancer Institute 1 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple MyelomaView official trial listing → -
Completed NCT NCT01535989
Study of Inotuzumab Ozogamicin + Temsirolimus in Patients With Relapsed or Refractory CD22+ B-cell NHLymphoma
Not yet reported Cristiana Sessa 25 participants Est. completion 2016-06 3 sitesOther conditions: B-cell Lymphoma RefractoryView official trial listing → -
Completed NCT NCT01536054
Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Not yet reported Roswell Park Cancer Institute 7 participants Est. completion 2015-04-21 1 site Stand-aloneOther conditions: Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Primary Peritoneal Cavity Cancer, Stage IIA Fallopian Tube Cancer, Stage IIA Ovarian Epithelial Cancer, Stage IIA Primary Peritoneal Cavity Cancer, Stage IIB Fallopian Tube Cancer, Stage IIB Ovarian Epithelial Cancer, Stage IIB Primary Peritoneal Cavity Cancer, Stage IIC Fallopian Tube Cancer, Stage IIC Ovarian Epithelial Cancer, Stage IIC Primary Peritoneal Cavity Cancer, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Epithelial Cancer, Stage IIIA Primary Peritoneal Cavity Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Epithelial Cancer, Stage IIIB Primary Peritoneal Cavity Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Epithelial Cancer, Stage IIIC Primary Peritoneal Cavity Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Epithelial Cancer, Stage IV Primary Peritoneal Cavity CancerView official trial listing → -
Completed NCT NCT01537107
Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By Surgery
Not yet reported Mayo Clinic 31 participants Est. completion 2018-06-27 3 sites Stand-aloneOther conditions: Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage IV Pancreatic Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT01543373
Optical Coherence Tomography Comparison of Neointimal Coverage Between CRE8 DES and BMS
Not yet reported CID - Carbostent & Implantable Devices 38 participants Est. completion 2014-04 6 sites Stand-aloneOther conditions: Stable Angina, Unstable Angina, NSTEMIView official trial listing → -
Completed NCT NCT01544491
Efficacy, Tolerability and Safety of Early Introduction of Everolimus, Reduced Calcineurin Inhibitors and Early Steroid Elimination Compared to Standard CNI, Mycophenolate Mofetil and Steroid Regimen in Paediatric Renal Transplant Recipients
Not yet reported Novartis Pharmaceuticals 106 participants Est. completion 2018-09-24 31 sitesOther conditions: Prevention of Acute Rejection in Paediatric Recipients of a Renal TransplantView official trial listing → -
Completed NCT NCT01545947
Study Assessing Safety, Pharmacokinetics and Efficacy of CC-223 With Either Erlotinib or Oral Azacitidine in Advanced Non-Small Cell Lung Cancer
Not yet reported Celgene 76 participants Est. completion 2014-12-11 9 sitesOther conditions: Carcinoma, Non-Small-Cell Lung, Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT01548482
Trebananib And Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Not yet reported National Cancer Institute (NCI) 21 participants Est. completion 2014-01 3 sitesOther conditions: Adult Solid Neoplasm, Lung Carcinoid Tumor, Recurrent Digestive System Neuroendocrine Tumor G1, Recurrent Renal Cell Carcinoma, Recurrent Uterine Corpus Sarcoma, Stage III Renal Cell Cancer, Stage IIIB Uterine Sarcoma, Stage IIIC Uterine Sarcoma, Stage IV Renal Cell Cancer, Stage IVA Uterine Sarcoma, Stage IVB Uterine SarcomaView official trial listing → -
Completed NCT NCT01548807
Phase 1 Trial of the Mammalian Target of Rapamycin (mTOR) Inhibitor Everolimus Plus Radiation Therapy (RT) for Salvage Treatment of Biochemical Recurrence in Prostate Cancer Patients Following Prostatectomy
Not yet reported Abramson Cancer Center at Penn Medicine 19 participants Est. completion 2017-01-04 1 siteOther conditions: Prostate Cancer Patients With Detectable PSA Following ProstatectomyView official trial listing → -
Completed NCT NCT01551212
Efficacy of Everolimus in Combination With Tacrolimus in Liver Transplant Recipients
Not yet reported Novartis Pharmaceuticals 339 participants Est. completion 2017-08-08 15 sitesOther conditions: Liver TransplantationView official trial listing → -
Terminated NCT NCT01552434
Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease
Not yet reported M.D. Anderson Cancer Center 154 participants Est. completion 2026-05-08 1 siteOther conditions: Advanced Malignant Neoplasm, Castleman Disease, Digestive System Carcinoma, Erdheim-Chester Disease, Lip and Oral Cavity Carcinoma, Lymphangioleiomyomatosis, Malignant Endocrine Neoplasm, Malignant Female Reproductive System Neoplasm, Malignant Male Reproductive System Neoplasm, Malignant Neoplasm, Malignant Respiratory Tract Neoplasm, Malignant Thoracic Neoplasm, Malignant Urinary System Neoplasm, Mesothelial Neoplasm, Metastatic Malignant Neoplasm, Metastatic Urothelial Carcinoma, Neurofibromatosis Type 2, Recurrent Adult Soft Tissue Sarcoma, Recurrent Breast Carcinoma, Recurrent Childhood Soft Tissue Sarcoma, Recurrent Digestive System Carcinoma, Recurrent Female Reproductive System Carcinoma, Recurrent Male Reproductive System Carcinoma, Recurrent Malignant Neoplasm, Recurrent Pharyngeal Carcinoma, Recurrent Thyroid Gland Carcinoma, Refractory Malignant Neoplasm, Soft Tissue Neoplasm, Stage III Breast Cancer AJCC v7, Stage III Pharyngeal Cancer, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Stage IV Breast Cancer AJCC v6 and v7, Stage IV Pharyngeal Cancer, Stage IVA Pharyngeal Cancer, Stage IVB Pharyngeal Cancer, Stage IVC Pharyngeal Cancer, Thyroid Gland NeoplasmView official trial listing → -
Completed NCT NCT01556126
Clinical Performance of CRE8 Drug Eluting Stent in All Comer Population
Not yet reported CID - Carbostent & Implantable Devices 1191 participants Est. completion 2018-12 23 sites Stand-aloneCardiovascular disease Other conditions: Stable Angina, Unstable AnginaView official trial listing → -
Terminated NCT NCT01561404
Effect of the Inhibition of the Mammalian Target of Rapamycin on Metabolism and Exercise
Not yet reported Josep M Cruzado 3 participants Est. completion 2013-12 1 siteOther conditions: Disorder Related to Renal Transplantation, Exercise, Aerobic, Muscle StrengthView official trial listing → -
Completed NCT NCT01563354
3-arm Trial to Evaluate Pasireotide LAR/Everolimus Alone/in Combination in Patients With Lung/Thymus NET - LUNA Trial
Not yet reported Novartis Pharmaceuticals 124 participants Est. completion 2020-02-10 36 sitesOther conditions: Neuroendocrine Carcinoma of the Lung and ThymusView official trial listing → -
Completed NCT NCT01566279
A Study to Identify a Biomarker Predictive for Response on Everolimus in Solid Tumors (CPCT-03)
Not yet reported UMC Utrecht 73 participants Est. completion 2016-11 3 sitesOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT01567475
The Combination of Rad001 and Rituximab In Patients With Non-hodgkin's Lymphomas
Not yet reported The Lymphoma Academic Research Organisation 21 participants Est. completion 2015-12 5 sitesOther conditions: Non-Hodgkin's LymphomasView official trial listing → -
Completed NCT NCT01567488
Phase II Study of Everolimus Combined With Octreotide LAR to Treat Advanced GI NET
Not yet reported Grupo Espanol de Tumores Neuroendocrinos 43 participants Est. completion 2017-06-07 1 siteOther conditions: Gastrointestinal NeoplasmsView official trial listing → -
Status unknown NCT NCT01567930
Temsirolimus as Second-line Therapy in HCC
Not yet reported University of Tennessee Cancer Institute 25 participants Est. completion 2013-03 1 siteOther conditions: Unresectable or Metastatic Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT01582009
Panobinostat and Everolimus in Treating Patients With Metastatic or Unresectable Renal Cell Cancer That Does Not Respond to Treatment With Sunitinib Malate or Sorafenib Tosylate
Not yet reported, Not yet reported Roswell Park Cancer Institute 26 participants Est. completion 2015-12 2 sitesOther conditions: Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Cancer, Stage III Renal Cell Cancer, Stage IV Renal Cell CancerView official trial listing → -
Terminated NCT NCT01582048
Multicenter Study of Peritransplantation Immunosuppression for Mismatched Hematopoietic Cell Transplantation After Reduced Intensity Conditioning
Not yet reported Prof. Dr. med. Wolfgang Bethge 9 participants Est. completion 2016-08-17 4 sitesOther conditions: Patients Receiving Mismatched Allogeneic HCTView official trial listing → -
Completed NCT NCT01582191
Vandetanib and Everolimus in Treating Patients With Advanced or Metastatic Cancer
Not yet reported M.D. Anderson Cancer Center 123 participants Est. completion 2025-10-22 1 siteOther conditions: Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm, Refractory Malignant NeoplasmView official trial listing → -
Completed NCT NCT01590199
Evaluate Safety and Tolerability of Pasireotide LAR in Combination With Everolimus in Advanced Metastatic NETs
Not yet reported Novartis Pharmaceuticals 18 participants Est. completion 2018-09-11 3 sitesOther conditions: Neuroendocrine TumorsView official trial listing → -
Status unknown NCT NCT01592253
Study to Evaluate Safety and Immunologic Biomarker of Rapamune in Patients With Stable Renal Transplant Recipient
Not yet reported Seoul St. Mary's Hospital 50 participants Est. completion 2013-12 1 siteOther conditions: Acute Rejection of Renal TransplantView official trial listing → -
Completed NCT NCT01594268
A Prospective, Open Label Study of CERtican in KIdney Transplantation
Not yet reported Novartis Pharmaceuticals 54 participants Est. completion 2013-10 4 sitesOther conditions: Kidney TransplantView official trial listing → -
Completed NCT NCT01595009
An Open-label, Multi-center, Expanded Access Study of Everolimus in Participants With Advanced Neuroendocrine Tumors (NETs) (Core Study) and an Extension Study to the Open-label, Multi-center, Expanded Access Study of Everolimus in Patients With Advanced NETs (E1)
Not yet reported Novartis Pharmaceuticals 246 participants Est. completion 2016-08-09 11 sitesOther conditions: Neuroendocrine TumorsView official trial listing → -
Completed NCT NCT01595841
Sirolimus Use in Angioplasty for Vascular Access Extension
Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 17 participants Est. completion 2022-03 1 site Stand-aloneOther conditions: End Stage Renal Disease, Venous StenosisView official trial listing → -
Completed NCT NCT01595984
Comparison of Efficacy and Safety of Treatment With a Calcineurin Inhibitor (CNI)Versus a CNI-free Treatment in Renal Transplantation (CIME)
Not yet reported Centre Hospitalier Universitaire, Amiens 88 participants Est. completion 2024-03-05 2 sitesOther conditions: Kidney FailureView official trial listing → -
Completed NCT NCT01596062
Pharmacodynamics, Efficacy and Safety of Basiliximab 40 or 80 mg in Combination With Ciclosporine Microemulsion or Everolimus, in Adult Low Risk de Novo Renal Transplant Recipients (IDEALE Study)
Not yet reported Novartis Pharmaceuticals 16 participants Est. completion 2013-03 3 sitesOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT01596140
Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced Cancer
Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2020-06-01 1 siteOther conditions: Advanced Cancer, Solid TumorView official trial listing → -
Completed NCT NCT01601821
Open Label Comparative Study Of De Novo Renal Allograft Recipients Receiving CSA + MMF + Corticosteroids Versus CSA + Rapamune + Corticosteroids
Not yet reported Pfizer 245 participants Est. completion 2008-03 4 sitesOther conditions: InflammationView official trial listing → -
Status unknown NCT NCT01608412
A Clinical Trial to Assess the Efficacy and Safety of the Conversion to Everolimus
Not yet reported Hospital de Clinicas de Porto Alegre 120 participants Est. completion 2014-07 1 siteOther conditions: Kidney Transplant RecipientsView official trial listing → -
Terminated NCT NCT01609673
Study of Everolimus in de Novo Renal Transplant Recipients
Not yet reported Helady Pinheiro, MD, PhD 1 participants Est. completion 2013-05 4 sitesOther conditions: End Stage Renal Failure With Renal TransplantView official trial listing → -
Completed NCT NCT01611116
Study With Temsirolimus Added to Standard Chemotherapy for Patients Over 60 Years With Acute Myeloblastic Leukemia
Not yet reported Goethe University 33 participants Est. completion 2017-04-26 5 sitesOther conditions: Acute Myeloblastic LeukemiaView official trial listing → -
Completed NCT NCT01614197
A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 16 participants Est. completion 2020-09-04 32 sitesOther conditions: Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Lymphoma, Peripheral T-cell LymphomaView official trial listing → -
Status unknown NCT NCT01614301
Phase I and Consecutive Phase II, Two-arm, Randomized Multi-center Trial in Patients With Advanced Melanoma
Not yet reported, Not yet reported University of Regensburg 136 participants Est. completion 2016-05 1 siteOther conditions: Advanced MelanomaView official trial listing → -
Completed NCT NCT01614795
Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma
Not yet reported National Cancer Institute (NCI) 46 participants Est. completion 2014-04-01 76 sitesObstructive sleep apnea Other conditions: Childhood Alveolar Soft Part Sarcoma, Childhood Epithelioid Sarcoma, Childhood Malignant Peripheral Nerve Sheath Tumor, Childhood Synovial Sarcoma, Recurrent Childhood Soft Tissue Sarcoma, Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorView official trial listing → -
Withdrawn NCT NCT01616186
Everolimus/Sorafenib or Sunitinib in Patients With Metastatic Renal Cell Carcinoma (RCC)
Not yet reported Andrea Harzstark Est. completion 2016-04Other conditions: Locally Metastatic Malignant NeoplasmView official trial listing → -
Completed NCT NCT01620307
Rapamune Improves Outcomes of Severe H1N1 Pneumonia
Not yet reported Chang Gung Memorial Hospital 38 participants Est. completion 2011-12Other conditions: H1N1 Pneumonia, HypoxemiaView official trial listing → -
Completed NCT NCT01624766
Everolimus and Anakinra or Denosumab in Treating Participants With Relapsed or Refractory Advanced Cancers
Not yet reported M.D. Anderson Cancer Center 57 participants Est. completion 2021-02-24 1 siteOther conditions: Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm, Refractory Malignant NeoplasmView official trial listing → -
Completed NCT NCT01624948
Safety and Efficacy Study of Everolimus to Treat BK Virus Infection in Kidney Transplant Recipients
Not yet reported University of California, San Francisco 40 participants Est. completion 2015-11 1 siteOther conditions: BK Virus InfectionView official trial listing → -
Completed NCT NCT01625156
Tivantinib and Temsirolimus in Treating Patients With Solid Tumors That is Metastatic or Cannot be Removed by Surgery
Not yet reported National Cancer Institute (NCI) 11 participants Est. completion 2015-10 2 sitesOther conditions: Adult Solid NeoplasmView official trial listing → -
Completed NCT NCT01625351
A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas
Not yet reported St. Jude Children's Research Hospital 23 participants Est. completion 2020-02-10 1 site Stand-aloneObstructive sleep apnea Other conditions: Ewing Sarcoma, Gastrointestinal Tumor, Germ Cell Tumor, Hepatic Tumor, Lymphoma, Wilms Tumor, Rhabdoid Tumor, Clear Cell Carcinoma, Renal Cell Carcinoma, Melanoma, NeuroblastomaView official trial listing → -
Completed NCT NCT01625377
A National Multi-center Randomized, Open Label Study to Evaluate Efficacy and Safety of Everolimus With EC-MPS Compared to Standard Treatment Combination Tacrolimus and EC-MPS in de Novo Liver Transplant Recipients
Not yet reported Novartis Pharmaceuticals 188 participants Est. completion 2015-03 14 sitesOther conditions: Liver TransplantationView official trial listing → -
Completed NCT NCT01625520
SOM230 Alone or in Combination With RAD001 in Patients With Medullary Thyroid Cancer
Not yet reported Federico II University 19 participants 1 siteOther conditions: Medullary Thyroid CancerView official trial listing → -
Completed NCT NCT01626170
Studying Mechanisms of Radiation Therapy Resistance in Samples From Younger Patients With Rhabdomyosarcoma
Children's Oncology Group 20 participants 1 siteObstructive sleep apneaView official trial listing → -
Completed NCT NCT01626222
4EVER - Efficacy, Safety, Health Economics, Translational Research of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer
Not yet reported Novartis Pharmaceuticals 301 participants Est. completion 2013-11 84 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Terminated NCT NCT01627067
Exemestane-RAD001-Metformin
Not yet reported M.D. Anderson Cancer Center 23 participants Est. completion 2019-02-01 1 siteOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT01628913
Efficacy and Safety of BEZ235 Compared to Everolimus in Patients With Advanced Pancreatic Neuroendocrine Tumors
Not yet reported Novartis Pharmaceuticals 62 participants Est. completion 2014-09 26 sitesOther conditions: Pancreatic Neuroendocrine Tumors (pNET)View official trial listing → -
Status unknown NCT NCT01631058
Renal Transplantation in the Elderly - nEverOld Study
Not yet reported University of Sao Paulo General Hospital 90 participants Est. completion 2019-06 2 sitesOther conditions: Chronic Renal Failure (CRF), Graft Failure, Transplant; Failure, Kidney, Renal Transplant RejectionView official trial listing → -
Completed NCT NCT01632605
The Vienna RAP Pilot Study
Not yet reported Medical University of Vienna 8 participants Est. completion 2012-04 1 site Stand-aloneOther conditions: ADPKDView official trial listing → -
Terminated NCT NCT01633060
A Phase III Study of BKM120 With Fulvestrant in Patients With HR+,HER2-, AI Treated, Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORi
Not yet reported Novartis Pharmaceuticals 432 participants Est. completion 2017-09-21 197 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT01634217
Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation
Not yet reported Masonic Cancer Center, University of Minnesota 16 participants Est. completion 2018-12-01 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Non-Hodgkin Lymphoma, Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Multiple Myeloma, Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT01636466
The Everolimus-Transplant Exit Strategy Trial (E-TEST)
Not yet reported Ashtar Chami 1 participants Est. completion 2014-05 1 siteOther conditions: Kidney Failure, ChronicView official trial listing → -
Completed NCT NCT01636908
Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies.
Not yet reported Amsterdam UMC, location VUmc 43 participants Est. completion 2019-12-01 1 siteOther conditions: Cancer, Advanced Solid TumorsView official trial listing → -
Completed NCT NCT01637012
Prospective, Single-arm, Multicenter Study for Evaluation the Safety and Effectiveness of the ALEX Stent in a Real-world Setting of Percutaneous Coronary Interventions in Patients With Coronary Heart Disease
Not yet reported Balton Sp.zo.o. 60 participants Est. completion 2013-09 5 sitesCardiovascular disease Other conditions: Stable Angina, Unstable AnginaView official trial listing → -
Terminated NCT NCT01637090
Everolimus in Treating Cutaneous T-cell Lymphoma
Not yet reported Adam Lerner 3 participants Est. completion 2015-05 1 siteOther conditions: Cutaneous T-Cell LymphomaView official trial listing → -
Completed NCT NCT01637194
Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck Cancer
Not yet reported Fox Chase Cancer Center 12 participants Est. completion 2011-07 1 siteOther conditions: Recurrent Adenoid Cystic Carcinoma of the Oral Cavity, Recurrent Basal Cell Carcinoma of the Lip, Recurrent Colon Cancer, Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity, Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity, Recurrent Lymphoepithelioma of the Nasopharynx, Recurrent Lymphoepithelioma of the Oropharynx, Recurrent Metastatic Squamous Neck Cancer With Occult Primary, Recurrent Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity, Recurrent Mucoepidermoid Carcinoma of the Oral Cavity, Recurrent Salivary Gland Cancer, Recurrent Squamous Cell Carcinoma of the Hypopharynx, Recurrent Squamous Cell Carcinoma of the Larynx, Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity, Recurrent Squamous Cell Carcinoma of the Nasopharynx, Recurrent Squamous Cell Carcinoma of the Oropharynx, Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Recurrent Verrucous Carcinoma of the Larynx, Recurrent Verrucous Carcinoma of the Oral Cavity, Stage IV Adenoid Cystic Carcinoma of the Oral Cavity, Stage IV Basal Cell Carcinoma of the Lip, Stage IV Lymphoepithelioma of the Nasopharynx, Stage IV Lymphoepithelioma of the Oropharynx, Stage IV Mucoepidermoid Carcinoma of the Oral Cavity, Stage IV Squamous Cell Carcinoma of the Hypopharynx, Stage IV Squamous Cell Carcinoma of the Larynx, Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity, Stage IV Squamous Cell Carcinoma of the Nasopharynx, Stage IV Squamous Cell Carcinoma of the Oropharynx, Stage IV Verrucous Carcinoma of the Larynx, Stage IV Verrucous Carcinoma of the Oral Cavity, Stage IVA Colon Cancer, Stage IVA Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity, Stage IVA Inverted Papilloma of the Paranasal Sinus and Nasal Cavity, Stage IVA Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity, Stage IVA Salivary Gland Cancer, Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Stage IVB Colon Cancer, Stage IVB Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity, Stage IVB Inverted Papilloma of the Paranasal Sinus and Nasal Cavity, Stage IVB Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity, Stage IVB Salivary Gland Cancer, Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Stage IVC Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity, Stage IVC Inverted Papilloma of the Paranasal Sinus and Nasal Cavity, Stage IVC Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity, Stage IVC Salivary Gland Cancer, Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Tongue CancerView official trial listing → -
Completed NCT NCT01640743
Effect of Different Therapeutic Strategies on Regulatory T Cells in Kidney Transplantation
Not yet reported Fondazione IRCCS Policlinico San Matteo di Pavia 58 participants Est. completion 2014-04 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT01642186
Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC)
Not yet reported Memorial Sloan Kettering Cancer Center 28 participants Est. completion 2021-07-16 6 sitesOther conditions: Fibrolamellar Carcinoma, Fibrolamellar Liver CancerView official trial listing → -
Terminated NCT NCT01642732
Study of Everolimus Added to Combined Hormonal and Radiation Therapy for High Risk Prostate Cancer
Not yet reported University of Michigan Rogel Cancer Center 1 participants Est. completion 2014-08 2 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT01646021
Study of Ibrutinib (a Bruton's Tyrosine Kinase Inhibitor), Versus Temsirolimus in Patients With Relapsed or Refractory Mantle Cell Lymphoma Who Have Received at Least One Prior Therapy
Not yet reported Janssen Research & Development, LLC 280 participants Est. completion 2016-12-15 92 sitesOther conditions: Mantle Cell LymphomaView official trial listing → -
Terminated NCT NCT01648465
Study of Everolimus Treatment in Newly-diagnosed Patients With Advanced Gastrointestinal Neuroendocrine Tumors
Not yet reported Hellenic Cooperative Oncology Group 25 participants Est. completion 2019-08-06 12 sitesOther conditions: Gastrointestinal Tumors, Pancreatic Tumors, Gastrointestinal Neuroendocrine Tumors, Pancreatic Neuroendocrine TumorsView official trial listing → -
Completed NCT NCT01649609
Using mTOR Inhibitors in the Prevention of BK Nephropathy
Not yet reported Columbia University 40 participants Est. completion 2016-12 2 sitesOther conditions: BK Viremia, BK NephropathyView official trial listing → -
Completed NCT NCT01649960
Exercise and Low-Dose Rapamycin in Older Adults With CAD:Cardiac Rehabilitation And Rapamycin in Elderly (CARE) Trial
Not yet reported Mayo Clinic 13 participants Est. completion 2015-12 1 siteOther conditions: Aging, CADView official trial listing → -
Completed NCT NCT01650545
Aerosol Liposomal Cyclosporine for Chronic Rejection in Lung Transplant Recipients
Not yet reported, Not yet reported University of Maryland, Baltimore 21 participants Est. completion 2019-11 1 siteOther conditions: Disorder Related to Lung Transplantation, Bronchiolitis Obliterans, Decreased Immunologic Activity, Chronic Rejection of Lung TransplantView official trial listing → -
Completed NCT NCT01651390
Clinical Performance of the Pantera Lux Balloon Versus the Orsiro Stent in Patients With In-stent Restenosis.
Not yet reported Biotronik AG 231 participants Est. completion 2016-07 14 sitesCardiovascular disease Other conditions: Coronary RestenosisView official trial listing → -
Completed NCT NCT01653041
Certican (Everolimus) for Recipients of Kidney From HLA-identical Living Donors
Not yet reported Hospital do Rim e Hipertensão 47 participants Est. completion 2015-04 1 siteOther conditions: Kidney TransplantationView official trial listing → -
Status unknown NCT NCT01653067
STORM: Temsirolimus, Rituximab and DHAP for Relapsed and Refractory Diffuse Large B-cell Lymphoma
Not yet reported Mathias Witzens-Harig 88 participants Est. completion 2018-07 9 sitesOther conditions: Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT01653847
Study in Recipients of Renal Transplant Allograft to Evaluate the Impact of Two Immunosuppressive Regimens
Not yet reported Northwestern University 88 participants Est. completion 2020-05 1 siteOther conditions: End Stage Renal Failure With Renal TransplantView official trial listing → -
Terminated NCT NCT01658007
Pilot Study Of Sirolimus Plus Multiagent Chemotherapy For Relapsed/Refractory Acute Lymphoblastic Leukemia/Lymphoma
Not yet reported Children's Hospital Medical Center, Cincinnati 3 participants Est. completion 2017-01 1 site Stand-aloneOther conditions: Relapsed Lymphoblastic Leukemia, Recurrent Adult Lymphoblastic Lymphoma, Refractory Acute Lymphoblastic Leukemia, Refractory Lymphoblastic LymphomaView official trial listing → -
Withdrawn NCT NCT01658176
Study Of PF-04691502 (PI3K/mTOR Inhibitor) In Combination With Exemestane Compared With Exemestane Alone In Patients With Advanced Breast Cancer
Not yet reported Pfizer Est. completion 2015-04Other conditions: Breast NeoplasmsView official trial listing → -
Completed NCT NCT01658436
BEZ235 Phase II Trial in Patients With Advanced Pancreatic Neuroendocrine Tumors (pNET) After Failure of mTOR Inhibitor Therapy.
Not yet reported Novartis Pharmaceuticals 31 participants Est. completion 2015-07 17 sitesOther conditions: Pancreatic Neuroendocrine Tumors (pNET)View official trial listing → -
Completed NCT NCT01661283
SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors
Not yet reported Sarcoma Alliance for Research through Collaboration 25 participants Est. completion 2017-12 12 sitesOther conditions: Malignant Peripheral Nerve Sheath Tumors, MPNST, SarcomaView official trial listing → -
Status unknown NCT NCT01663805
Effects of the Use of "de Novo" Everolimus in Renal Tranplant Population
Not yet reported MARIO ABBUD FILHO 80 participants Est. completion 2015-06 3 sitesOther conditions: Delayed Function of Renal TransplantView official trial listing → -
Completed NCT NCT01665768
Maintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in Lymphoma
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 56 participants Est. completion 2020-08 1 siteOther conditions: CD20+, B-cell Lymphomas, Mantle Cell Lymphoma, Non-Mantle Cell Low Grade B Cell Lymphomas (SLL/CLL), Transformed Lymphoma/DLBCL/PMBCL, Hodgkin's Disease, Gray Zone LymphomaView official trial listing → -
Completed NCT NCT01668784
Study of Nivolumab (BMS-936558) vs. Everolimus in Pre-Treated Advanced or Metastatic Clear-cell Renal Cell Carcinoma (CheckMate 025)
Not yet reported Bristol-Myers Squibb 821 participants Est. completion 2021-07-19 168 sitesOther conditions: Advanced or Metastatic (Medically or Surgically Unresectable) Clear-cell Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01670175
Sirolimus With Cyclophosphamide and Topotecan for Pediatric/Adolescent Relapsed and Refractory Solid Tumors
Not yet reported University of California, San Francisco 21 participants Est. completion 2016-09 1 site Stand-aloneOther conditions: Malignant Solid Tumor, Childhood Solid TumorView official trial listing → -
Completed NCT NCT01672151
Efficacy of Rapamycin Therapy With Chronic Immune Thrombocytopenia
First Affiliated Hospital of Suzhou Medical College 35 participants Est. completion 2012-08 1 siteOther conditions: Immune Thrombocytopenic PurpuraView official trial listing → -
Active, not recruiting NCT NCT01674140
S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
Not yet reported SWOG Cancer Research Network 1939 participants Est. completion 2030-01 1459 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01674803
Comparison of BIOdegradable Polymer and DuRablE Polymer Drug-eluting Stents in an All COmeRs PopulaTion (BIO-RESORT)
Not yet reported Foundation of Cardiovascular Research and Education Enschede 3514 participants Est. completion 2020-08-25 1 siteCardiovascular disease Other conditions: Acute Coronary Syndrome, Angina Pectoris, Angina, Unstable, Coronary Stenosis, Coronary RestenosisView official trial listing → -
Terminated NCT NCT01675947
Intravitreal Injections of Sirolimus in the Treatment of Geographic Atrophy
Not yet reported National Eye Institute (NEI) 52 participants Est. completion 2016-02 13 sites Stand-aloneOther conditions: Geographic AtrophyView official trial listing → -
Terminated NCT NCT01677390
A Phase 1b Study of SGN-75 in Combination With Everolimus in Patients With Renal Cell Carcinoma
Not yet reported Seagen Inc. 4 participants Est. completion 2013-12 8 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01678664
Everolimus After (Chemo)Embolization for Liver Metastases From Digestive Endocrine Tumors
Not yet reported Federation Francophone de Cancerologie Digestive 74 participants Est. completion 2019-04 18 sitesOther conditions: Neuroendocrine Tumors, Hepatic Metastases, MetastasesView official trial listing → -
Completed NCT NCT01678937
Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents
Northwestern University 31 participants Est. completion 2008-09 1 siteOther conditions: Liver Transplant Rejection, ImmunosuppressionView official trial listing → -
Status unknown NCT NCT01680250
Sirolimus for Massive Polycystic Liver
Not yet reported, Not yet reported Seoul National University Hospital 44 participants Est. completion 2015-08 1 site Stand-aloneOther conditions: Polycystic Kidney DiseasesView official trial listing → -
Completed NCT NCT01680861
Tacrolimus/Everolimus Versus Tacrolimus/Enteric-Coated Mycophenolate Sodium
Not yet reported Gaetano Ciancio 32 participants Est. completion 2014-12 1 siteOther conditions: Transplant; Failure, KidneyView official trial listing → -
Completed NCT NCT01680952
Study to Evaluate the Safety and Efficacy of Extended Release Tacrolimus (Advagraf®) + Sirolimus (Rapamune®), Versus Extended Release Tacrolimus (Advagraf®) + Mycophenolate Mofetil in Kidney Transplant Patients
Not yet reported Yonsei University 158 participants Est. completion 2016-01 7 sites Stand-aloneOther conditions: Kidney Transplant PatientsView official trial listing → -
Status unknown NCT NCT01681381
Evaluate Safety And Effectiveness Of The Tivoli® DES and The Firebird2® DES For Treatment Coronary Revascularization
Not yet reported Essen Technology (Beijing) Co., Ltd. 2790 participants Est. completion 2018-09 1 siteOther conditions: Ischemic Heart Disease, Myocardial Ischemia, Coronary Artery Lesions,Primary, Coronary Disease, Acute Coronary Syndrome, Furcation Lesion of Coronary ArteryView official trial listing → -
Completed NCT NCT01684449
Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma
Not yet reported, Not yet reported Grupo Espanol de Investigacion en Sarcomas 28 participants Est. completion 2013-12 9 sitesOther conditions: Advanced Soft Tissue SarcomaView official trial listing → -
Completed NCT NCT01684982
Everolimus Stent in Myocardial Infarction
Not yet reported San Giuseppe Moscati Hospital 500 participants Est. completion 2012-06 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01687075
CRE8 in All Comers Patients
Not yet reported Tel-Aviv Sourasky Medical Center 215 participants Est. completion 2014-08 1 site Stand-aloneOther conditions: Consecutive Subjects Who Are Suitable for a Coronary, Angioplasty of de Novo Lesion(s) in Native Coronary, Arteries Should be Screened for Eligibility., A Total Number of 200 Patients Fulfilling the Selection, Criteria and Willing to Sign the Informed Consent Should, be Enrolled in the Trial.View official trial listing → -
Completed NCT NCT01687179
Safety Study of Sirolimus and Hydroxychloroquine in Women With Lymphangioleiomyomatosis
Not yet reported Brigham and Women's Hospital 14 participants Est. completion 2015-08 1 site Stand-aloneOther conditions: LymphangioleiomyomatosisView official trial listing → -
Completed NCT NCT01687673
Phase II Combination of Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma
Not yet reported University of California, San Francisco 29 participants Est. completion 2020-01-09 2 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT01689987
Hydroxychloroquine, Cyclophosphamide, Dexamethasone, and Sirolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported OHSU Knight Cancer Institute 18 participants 1 site Stand-aloneOther conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell MyelomaView official trial listing → -
Completed NCT NCT01698918
Open-label, Phase II, Study of Everolimus Plus Letrozole in Postmenopausal Women With ER+, HER2- Metastatic or Locally Advanced Breast Cancer
Not yet reported Novartis Pharmaceuticals 202 participants Est. completion 2021-01-13 52 sitesOther conditions: Hormone Receptor Positive Breast CancerView official trial listing → -
Status unknown NCT NCT01699360
The Biomarker for Immunosuppressive Agents Metabolism in Chinese Renal Transplant Recipients
Not yet reported Central South University 600 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT01700400
Study of Everolimus, Pemetrexed, Carboplatin, and Bevacizumab to Treat Stage IV Lung Cancer
Not yet reported Cancer Research and Biostatistics Clinical Trials Consortium 13 participants Est. completion 2014-10 4 sitesOther conditions: Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT01706471
Safety and Efficacy of the Early Introduction of Everolimus (Certican®) With Low Dose of Cyclosporine in de Novo Kidney Recipients After 1 Month of Transplantation
Not yet reported Yonsei University 60 participants Est. completion 2013-04 1 siteOther conditions: Planned Kidney TransplantationView official trial listing → -
Completed NCT NCT01707849
The Impact of Everolimus Based Immunosuppression in the Evolution of Hepatitis C Fibrosis After Liver Transplantation
Not yet reported Hospital Vall d'Hebron 18 participants Est. completion 2016-08 1 siteOther conditions: Hepatitis C Recurrence After Liver TransplantView official trial listing → -
Terminated NCT NCT01709136
Pharmacokinetics of Sirolimus and Tacrolimus in Liver Transplant Recipients With Tacrolimus Toxicity
Not yet reported, Not yet reported University of Pittsburgh 3 participants Est. completion 2010-01 Stand-aloneOther conditions: HypertensionView official trial listing → -
Completed NCT NCT01712828
Effect of P-glycoprotein Inhibition on Lenalidomide Pharmacokinetics in Healthy Males
Not yet reported Celgene 31 participants Est. completion 2013-01-01 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01713400
Tacrolimus, Sirolimus and Ustekinumab vs. Tacrolimus and Sirolimus for the Prevention of Acute Graft-Versus-Host Disease
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 54 participants Est. completion 2018-06-14 1 site Stand-aloneOther conditions: Graft vs. Host DiseaseView official trial listing → -
Completed NCT NCT01713946
A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures
Not yet reported Novartis Pharmaceuticals 366 participants Est. completion 2017-10-25 104 sitesOther conditions: Tuberous Sclerosis Complex-associated Refractory SeizuresView official trial listing → -
Completed NCT NCT01714765
Dose Escalation Study Investigating Everolimus and Dovitinib in Metastatic Clear Cell Renal Cancer
Not yet reported Queen Mary University of London 17 participants Est. completion 2012-10 1 siteOther conditions: Metastatic Clear Cell Renal CancerView official trial listing → -
Completed NCT NCT01715935
Biomarkers Before and After Nephrectomy of Locally Advanced or Metastatic Renal Cell Carcinoma Treated With Everolimus
Not yet reported Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie 25 participants Est. completion 2016-04 10 sitesOther conditions: Clear-cell Renal Carcinoma, Clear-cell Metastatic Renal Cell CarcinomaView official trial listing → -
Status unknown NCT NCT01730209
Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex
Not yet reported, Not yet reported Erasmus Medical Center 60 participants Est. completion 2016-11 1 siteOther conditions: Tuberous Sclerosis Complex, TSC Related Cognitive Disability, TSC Related Autism, TSC Related Learning ProblemsView official trial listing → -
Completed NCT NCT01731158
Sequential Therapy in Metastatic Renal Cell Carinoma
Not yet reported Central European Society for Anticancer Drug Research 22 participants Est. completion 2016-09 13 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01734512
PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children
Not yet reported University of California, San Francisco 65 participants Est. completion 2024-07-31 18 sitesOther conditions: Pediatric Recurrent Progressive Low-grade Gliomas, Pediatric Progressive Low-grade GliomasView official trial listing → -
Completed NCT NCT01737502
Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer
Not yet reported, Not yet reported Mayo Clinic 29 participants Est. completion 2023-04-24 2 sites Stand-aloneOther conditions: Extensive Stage Small Cell Lung Carcinoma, Lung Adenocarcinoma, Recurrent Non-Small Cell Lung Carcinoma, Recurrent Small Cell Lung Carcinoma, Squamous Cell Lung Carcinoma, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung Cancer, Stage IV Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT01743560
An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Treated With Everolimus (RAD001) With Exemestane, With Exploratory Epigenetic Marker Analysis
Not yet reported Novartis Pharmaceuticals 52 participants Est. completion 2016-08-15 11 sitesOther conditions: Oestrogen Receptor Positive Advanced Breast CancerView official trial listing → -
Completed NCT NCT01754389
Standard of Care vs. Bortezomib in Graft-Versus Host Disease After Hematopoietic Stem Cell Transplant
Not yet reported Dana-Farber Cancer Institute 138 participants Est. completion 2016-11 4 sites Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT01756118
A Phase I, Dose-finding Study of BEZ235 in Adult Patients With Relapsed or Refractory Acute Leukemia
Not yet reported Goethe University 24 participants Est. completion 2020-02-07 1 siteOther conditions: Acute Lymphoblastic Leukemia, Leukemia, Myelocytic, Acute, Chronic Myelogenous Leukemia With Crisis of Blast CellsView official trial listing → -
Completed NCT NCT01756807
EGO-COMBO Angiographic Extension Study
Not yet reported Prof. Stephen Lee 41 participants Est. completion 2013-06 1 site Stand-aloneOther conditions: Coronary DiseaseView official trial listing → -
Status unknown NCT NCT01758107
Study of Cyclosporine Withdrawal Regimen in Thai Renal Transplant Recipients
Not yet reported Chulalongkorn University 30 participants Est. completion 2015-10 1 site Stand-aloneOther conditions: Renal TransplantView official trial listing → -
Terminated NCT NCT01758575
Clinical Evaluation of the Underlying Mechanisms of Targeted Therapy Related Toxicities
Amsterdam UMC, location VUmc 8 participants Est. completion 2017-04 1 siteOther conditions: Advanced or Metastatic Solid MalignancyView official trial listing → -
Suspended NCT NCT01762410
Clinical Study of Oral PI3K/mTOR Inhibitor in Patients With Advanced Refractory Solid Tumors
Not yet reported Piramal Enterprises Limited 60 participants Est. completion 2016-03 4 sitesOther conditions: Advanced Refractory Solid TumorsView official trial listing → -
Terminated NCT NCT01764607
Sirolimus in Kidney Transplant Patients With Squamous Cell Skin Carcinoma
Not yet reported University of Florida 1 participants Est. completion 2014-06 1 site Stand-aloneOther conditions: Squamous Cell Skin CarcinomaView official trial listing → -
Completed NCT NCT01767194
Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma
Not yet reported National Cancer Institute (NCI) 73 participants Est. completion 2022-09-30 157 sitesOther conditions: Ganglioneuroblastoma, Recurrent NeuroblastomaView official trial listing → -
Terminated NCT NCT01773460
Everolimus Beyond Progress for Patients Who Had Progress Under Everolimus and Exemestane
Not yet reported GBG Forschungs GmbH 3 participants Est. completion 2014-07 1 siteOther conditions: Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT01777204
Gastrointestinal Transit and Motility in Renal Transplant Recipients
Universidade Estadual de Ciências da Saúde de Alagoas 20 participants Est. completion 2013-01 1 siteOther conditions: Change of Transit or Circulation, Effects of Immunosuppressant TherapyView official trial listing → -
Completed NCT NCT01780948
Pharmacokinetic of Everolimus and Atorvastatin Co-administration
Not yet reported Chulalongkorn University 18 participants Est. completion 2013-01 1 siteOther conditions: Difference of 12-hour AUCView official trial listing → -
Withdrawn NCT NCT01781442
A Post Marketing Surveillance As Required By Philippine Food And Drug Administration
Pfizer Est. completion 2015-06Other conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01783444
A Phase II Study of Everolimus in Combination With Exemestane Versus Everolimus Alone Versus Capecitabine in Advance Breast Cancer.
Not yet reported Novartis Pharmaceuticals 309 participants Est. completion 2018-07-30 83 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01783756
Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS Metastasis
Not yet reported, Not yet reported Jonsson Comprehensive Cancer Center 9 participants Est. completion 2019-05-10 1 siteOther conditions: Central Nervous System Metastases, HER2-positive Breast Cancer, Male Breast Cancer, Recurrent Breast Cancer, Stage IV Breast CancerView official trial listing → -
Terminated NCT NCT01784861
VEGFR/PDGFR Dual Kinase Inhibitor X-82 and Everolimus for Treating Patients With Pancreatic Neuroendocrine Tumors
Not yet reported, Not yet reported Washington University School of Medicine 23 participants Est. completion 2020-08-19 2 sitesOther conditions: Adenocarcinoma, Pancreatic NeoplasmsView official trial listing → -
Terminated NCT NCT01784978
Efficacy Study of Sunitinib and Everolimus (Rotational vs Sequential Arm) in Pats. With m Clear Cell Renal Cancer
Not yet reported Associació per a la Recerca Oncologica, Spain 41 participants Est. completion 2017-05-08 10 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01788150
Safety and Efficacy Study of the Svelte Drug-Eluting Coronary Stent Delivery System
Not yet reported Svelte Medical Systems, Inc. 159 participants Est. completion 2019-05-31 18 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT01789281
Everolimus Roll-over Protocol for Patients Who Have Completed a Previous Novartis-sponsored Everolimus Study.
Not yet reported Novartis Pharmaceuticals 34 participants Est. completion 2020-08-28 24 sitesOther conditions: NeoplasmsView official trial listing → -
Completed NCT NCT01791088
Sirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery
Not yet reported University of Chicago 56 participants Est. completion 2018-08-17 1 site Stand-aloneOther conditions: Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol SpecificView official trial listing → -
Terminated NCT NCT01793636
A Study Comparing AZD2014 vs Everolimus in Patients With Metastatic Renal Cancer
Not yet reported Queen Mary University of London 49 participants Est. completion 2015-11 9 sitesOther conditions: Metastatic Clear Cell Renal CarcinomaView official trial listing → -
Completed NCT NCT01797120
Study of Fulvestrant +/- Everolimus in Post-Menopausal, Hormone-Receptor + Metastatic Breast Ca Resistant to AI
Not yet reported PrECOG, LLC. 131 participants Est. completion 2017-09-12 25 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Terminated NCT NCT01797315
Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive Protocol
Not yet reported University Hospital of Berlin 40 participants Est. completion 2013-06Other conditions: Renal Transplant Patients at High-risk for Skin CancerView official trial listing → -
Completed NCT NCT01797523
A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma
Not yet reported M.D. Anderson Cancer Center 62 participants Est. completion 2026-02-04 6 sitesOther conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT01798446
A Phase II Study of Axitinib in Metastatic Non-clear Cell Renal Cell Carcinoma Patients Previously Treated With Temsirolimus
Not yet reported Seoul National University Hospital 41 participants Est. completion 2016-12 1 siteOther conditions: Renal Cell Carcinoma, Nonclear Cell, Temsirolimus ResistanceView official trial listing → -
Completed NCT NCT01801137
The Efficacy of RAD 001 as Second Line Therapy in Patients With Transitional Cell Carcinoma TCC of the Urothelium
Not yet reported Hopital Foch 54 participants Est. completion 2014-10 1 siteOther conditions: Urothelial CancerView official trial listing → -
Completed NCT NCT01802268
Planned Conversion From TAC to SRL-based Regimen in de Novo Kidney Transplant Recipients
Not yet reported Helio Tedesco Silva Junior 320 participants Est. completion 2012-10 6 sitesOther conditions: Kidney TransplantView official trial listing → -
Completed NCT NCT01804374
Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma
Not yet reported Italian Sarcoma Group 38 participants Est. completion 2014-12 1 siteObstructive sleep apneaView official trial listing → -
Active, not recruiting NCT NCT01805271
Safety Study of Adding Everolimus to Adjuvant Hormone Therapy in Women With High Risk of Relapse, ER+ and HER2- Primary Breast Cancer, Free of Disease After Receiving at Least One Year of Adjuvant Hormone Therapy
Not yet reported UNICANCER 1278 participants Est. completion 2030-06 2 sitesOther conditions: Primary Non-metastatic Breast Cancer, Who Remain Disease-freeView official trial listing → -
Withdrawn NCT NCT01807767
Myfortic in High MELD Liver Transplantation
Not yet reported Medical College of Wisconsin Est. completion 2015-08 1 siteOther conditions: High Model for End-Stage Liver Disease (MELD) ScoreView official trial listing → -
Completed NCT NCT01809860
A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy Subjects
Not yet reported Astellas Pharma Global Development, Inc. 22 participants Est. completion 2012-01 1 site Stand-aloneOther conditions: Healthy Subjects, Pharmacokinetics of Isavuconazole, Pharmacokinetics of SirolimusView official trial listing → -
Completed NCT NCT01811667
Efficacy and Safety of the Mammalian Target of Rapamycin (mTor Rapamycin) Inhibitor in Vascular Malformations
Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 19 participants Est. completion 2016-01 1 site Stand-aloneOther conditions: Cardiovascular AbnormalitiesView official trial listing → -
Terminated NCT NCT01814059
Sirolimus for Eosinophil-Associated Gastrointestinal Disorders
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 4 participants Est. completion 2015-05-12 1 siteOther conditions: Eosinophilic Gastroenteritis, Eosinophilic EsophagitisView official trial listing → -
Completed NCT NCT01817504
Systematic Transplantectomy Versus Conventional Care After Kidney Graft Failure
Not yet reported Hospices Civils de Lyon 56 participants Est. completion 2021-11 9 sitesOther conditions: Renal TransplantationView official trial listing → -
Completed NCT NCT01822015
Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 55 participants Est. completion 2019-12-12 1 site Stand-aloneOther conditions: Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Erythroleukemia (M6a), Adult Pure Erythroid Leukemia (M6b), Untreated Adult Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01827267
Neratinib With and Without Temsirolimus for Patients With HER2 Activating Mutations in Non-Small Cell Lung Cancer
Not yet reported Puma Biotechnology, Inc. 62 participants Est. completion 2017-10-06 21 sitesOther conditions: HER2-mutant Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT01827384
MPACT Study to Compare Effects of Targeted Drugs on Tumor Gene Variations
Not yet reported National Cancer Institute (NCI) 208 participants Est. completion 2021-10-08 8 sitesOther conditions: Advanced Malignant Solid NeoplasmView official trial listing → -
Completed NCT NCT01827618
Neoadjuvant Rapamycin in Patients Undergoing Radical Cystectomy
Not yet reported The University of Texas Health Science Center at San Antonio 29 participants Est. completion 2014-04 1 siteOther conditions: Invasive Bladder Cancer Stage IIView official trial listing → -
Completed NCT NCT01827943
Phase II Evaluating Efficacy of Temsirolimus in 2 Line Therapy for Patients With Advanced Bladder Cancer
Not yet reported Institut Bergonié 54 participants Est. completion 2016-12 9 sitesOther conditions: Relapsed Bladder CancerView official trial listing → -
Completed NCT NCT01830153
RAD001 in Advanced Sarcoma
Not yet reported Asan Medical Center 41 participants 8 sitesOther conditions: Soft Tissue Sarcomas, Bone SarcomasView official trial listing → -
Terminated NCT NCT01842594
A Phase II Trial of Combined Hydroxychloroquine and Sirolimus in Soft Tissue Sarcoma
Not yet reported Shin Kong Wu Ho-Su Memorial Hospital 13 participants Est. completion 2015-01 1 site Stand-aloneOther conditions: SarcomaView official trial listing → -
Completed NCT NCT01843348
12 Month Athena Study: Everolimus vs. Standard Regimen in de Novo Kidney Transplant Patients
Not yet reported Novartis Pharmaceuticals 612 participants Est. completion 2016-03-23 27 sitesOther conditions: Kidney Transplantation, Renal TransplantationView official trial listing → -
Withdrawn NCT NCT01843998
Therapeutic Efficacy of Topical Sirolimus in Early Stage Cutaneous T-cell Lymphoma (CTCL)
Not yet reported Stefan Schieke MD Est. completion 2015-12 1 site Stand-aloneOther conditions: Cutaneous T-cell Lymphoma (CTCL)View official trial listing → -
Completed NCT NCT01845311
ReZolve2 Clinical Investigation
Not yet reported REVA Medical, Inc. 89 participants Est. completion 2019-01 3 sitesCardiovascular disease Other conditions: Coronary Artery StenosisView official trial listing → -
Status unknown NCT NCT01850108
Non-Myeloablative Conditioning and Bone Marrow Transplantation
Not yet reported Vanderbilt-Ingram Cancer Center 26 participants Est. completion 2024-12-31 3 sites Stand-aloneOther conditions: Sickle Cell Disease, HemoglobinopathiesView official trial listing → -
Withdrawn NCT NCT01851408
Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma
Not yet reported National Cancer Institute (NCI) Est. completion 2012-02Other conditions: Melanoma, Recurrent Melanoma, Stage III Melanoma, Stage IV MelanomaView official trial listing → -
Completed NCT NCT01853423
Tuberous Sclerosis Complex: Facial Angiofibroma Skin Cream
Not yet reported Le Bonheur Children's Hospital 11 participants Est. completion 2016-07 1 siteOther conditions: Facial AngiofibromaView official trial listing → -
Completed NCT NCT01854606
Safety and Efficacy of AEB071 and EVEROLIMUS in Patients With CD79-mutant or ABC Subtype Diffuse Large B-Cell Lymphoma
Not yet reported Novartis Pharmaceuticals 31 participants Est. completion 2016-06-01 15 sitesOther conditions: CD79 Mutant or ABC-subtype Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT01856088
DESTINY TRIAL (Inspiron x Biomatrix)
Not yet reported Scitech Produtos Medicos SA 170 participants Est. completion 2019-03-21 10 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT01856101
Study of BEZ235 as Monotherapy in Patients With Transitional Cell Carcinoma After Failure of Platinum Based Chemotherapy
Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 22 participants Est. completion 2014-01 12 sitesOther conditions: Carcinoma Transitional CellView official trial listing → -
Completed NCT NCT01856374
Serial EValuation of multiplE Coronary Artery Diseases by an Optical Coherence Tomography; Assessment of the Changes of de Novo Lesions and Comparisons of Neointimal Coverage Between Xience Prime® Versus Cypher SelectTM Stents; SEVEN-Xience Study
Not yet reported Yonsei University 60 participants Est. completion 2014-10 1 siteOther conditions: Multi-vessel Diseases, AnginaView official trial listing → -
Withdrawn NCT NCT01864070
Phase 1 TheraSphere + Everolimus With Neuroendocrine Tumors (NETs) + Liver Only or Liver Dominant Disease
Not yet reported M.D. Anderson Cancer CenterOther conditions: Liver CancerView official trial listing → -
Completed NCT NCT01865747
A Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma
Not yet reported Exelixis 658 participants Est. completion 2021-01-15 205 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01869114
Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 57 participants Est. completion 2024-01-03 5 sites Stand-aloneOther conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), de Novo Myelodysplastic Syndromes, Myelodysplastic Syndrome With Isolated Del(5q), Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT01874002
Prospective Registry to Asses the Long-term Safety and Performance of the Combo Stent
Robbert J de Winter 1000 participants Est. completion 2019-03 9 sitesCardiovascular diseaseView official trial listing → -
Terminated NCT NCT01878786
A Pilot Study Comparing the Safety and Efficacy of Everolimus With Other Medicines in Recipients of ECD/DCD Kidneys
Not yet reported, Not yet reported Matthew Cooper 25 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: Delayed Graft FunctionView official trial listing → -
Status unknown NCT NCT01879358
Sirolimus Eluting ORSIRO Stent Versus Biolimus-eluting NOBORI Stent
Not yet reported Odense University Hospital 2314 participants Est. completion 2021-02-01 1 siteCardiovascular disease Other conditions: Ischemic Heart DiseaseView official trial listing → -
Completed NCT NCT01880749
Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas
Not yet reported NYU Langone Health 5 participants Est. completion 2019-12 1 siteOther conditions: Neurofibromatosis Type 2, Vestibular Schwannomas, MeningiomasView official trial listing → -
Status unknown NCT NCT01880879
A Prospective Multicenter Trial Evaluating Helios Biodegradable Polymer SES Safety and Effectiveness in CAD Treatment
Not yet reported Kinhely Bio-tech Co., Ltd. 800 participants Est. completion 2015-01 1 siteCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT01885689
Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia
Not yet reported City of Hope Medical Center 72 participants Est. completion 2026-09-21 1 site Stand-aloneOther conditions: Adult Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Adult Acute Myeloid Leukemia in Remission, Myelodysplastic Syndrome, Secondary Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, Therapy-Related Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01887704
Effect of Rotablator on Balloon Resistant Calcified Coronary Lesion
Not yet reported Capital Medical University 240 participants Est. completion 2013-05 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT01888042
Assessing Everolimus in Fist Line Treatment on Patients With Metastatic Kidney Cancer
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 61 participants Est. completion 2014-07 1 siteOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT01888302
Sirolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients At High Risk for Cholangiocarcinoma Recurrence After Liver Transplant or Surgery
Not yet reported Mayo Clinic 1 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Hepatic ComplicationView official trial listing → -
Completed NCT NCT01888432
Efficacy and Safety of Everolimus in Liver Transplant Recipients of Living Donor Liver Transplants
Not yet reported Novartis Pharmaceuticals 285 participants Est. completion 2018-04-21 42 sitesOther conditions: Liver TransplantationView official trial listing → -
Terminated NCT NCT01889420
Phase I Trial of Everolimus, Pomalidomide and Dexamethasone in Patients With Relapsed/Refractory Multiple Myeloma
Not yet reported New Mexico Cancer Research Alliance 1 participants Est. completion 2015-07 1 siteOther conditions: Multiple Myeloma in RelapseView official trial listing → -
Terminated NCT NCT01889992
Cardiac Allograft Remodeling and Effects of Sirolimus
Not yet reported University of Nebraska 42 participants Est. completion 2018-09-27 1 site Stand-aloneOther conditions: Cardiac Hypertrophy, ImmunosuppressionView official trial listing → -
Completed NCT NCT01895049
Comparison Between Two Tacrolimus-based Immunosuppressant Regimens and Induction With Thymoglobulin in Kidney Transplants From Deceased Donors With Expanded Criteria
Not yet reported Helio Tedesco Silva Junior 171 participants Est. completion 2017-03-07 1 siteOther conditions: Kidney Transplantation, CytomegalovirusView official trial listing → -
Completed NCT NCT01902160
Temsirolimus and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
Not yet reported National Cancer Institute (NCI) 3 participants 1 siteOther conditions: Recurrent Adult Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT01903473
Donor Regulatory T Cells Infusion in Patients With Chronic Graft-versus-host Disease (GVHD)
Not yet reported University of Liege 19 participants Est. completion 2022-09-12 2 sitesOther conditions: Chronic Graft-Versus-Host Disease, Acute Graft-Versus-Host Disease, Steroid Refractory Graft-Versus-Host DiseaseView official trial listing → -
Completed NCT NCT01909869
A Pilot First In Man Study of EXCEL-Ⅱto Treat the Patients With de Novo Coronary Artery Lesions
Not yet reported JW Medical Systems Ltd 45 participants Est. completion 2019-06-04 1 site Stand-aloneCardiovascular disease Other conditions: IschemiaView official trial listing → -
Completed NCT NCT01911546
Role of Everolimus in Highly Sensitized Patients
Not yet reported Joseph Kahwaji, MD, MPH 20 participants Est. completion 2016-01-19 1 siteOther conditions: Highly-sensitized Kidney Transplant RecipientsView official trial listing → -
Completed NCT NCT01914770
Effectiveness of Belimumab Treatment in a Subpopulation of Systemic Lupus Erythematosus (SLE) Patients: a Pooled Analysis of BLISS-52 and BLISS-76
GlaxoSmithKline 1016 participants Est. completion 2010-11Other conditions: Systemic Lupus ErythematosusView official trial listing → -
Completed NCT NCT01920061
A Study Of PF-05212384 In Combination With Other Anti-Tumor Agents and in Combination With Cisplatin in Patients With Triple Negative Breast Cancer in an Expansion Arm (TNBC)
Not yet reported Pfizer 110 participants Est. completion 2020-01-08 29 sitesOther conditions: NeoplasmView official trial listing → -
Completed NCT NCT01924962
Recovery of Left Ventricular Function in Chronic Total Occluded Coronary Arteries
Not yet reported University Heart Center Freiburg - Bad Krozingen 205 participants Est. completion 2017-06-16 1 siteOther conditions: Coronary Heart DiseaseView official trial listing → -
Status unknown NCT NCT01925027
Efficacy and Safety of Nano+ Polymer-free Sirolimus-Eluting Stent: A Optical Coherent Tomography Study
Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 45 participants Est. completion 2016-11 5 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01927120
In Vivo Treg Expansion and Graft-Versus-Host Disease Prophylaxis
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 20 participants Est. completion 2017-03-09 1 site Stand-aloneOther conditions: Graft-Versus-Host-DiseaseView official trial listing → -
Status unknown NCT NCT01927588
Evaluation of Early Use of Everolimus (EVE) on Cytomegalovirus (CMV) Infection in Renal Transplant Recipients
Not yet reported Fundação Pró Rim 50 participants Est. completion 2015-11Other conditions: Cytomegalovirus InfectionsView official trial listing → -
Completed NCT NCT01929642
Rapalogues for Autism Phenotype in TSC: A Feasibility Study
Not yet reported Hugo W. Moser Research Institute at Kennedy Krieger, Inc. 3 participants Est. completion 2016-08 1 site Stand-aloneOther conditions: Tuberous Sclerosis Complex, Self-injury, AutismView official trial listing → -
Completed NCT NCT01931163
NECTAR Everolimus Plus Cisplatin in Triple (-) Breast Cancer
Not yet reported Jenny C. Chang, MD 24 participants Est. completion 2019-01 3 sitesOther conditions: Breast Cancer, Triple Negative Breast CancerView official trial listing → -
Status unknown NCT NCT01932177
EVESOR: a Phase 1 Trial of Everolimus and Sorafenib
Not yet reported Hospices Civils de Lyon 60 participants Est. completion 2015-10 1 siteOther conditions: Metastatic or Locally Advanced Solid TumorsView official trial listing → -
Completed NCT NCT01935128
Evaluation of Calcineurin-inhibitor Reduction With Conversion at 2 Months to Everolimus/Reduced Tacrolimus in Renal Transplant Recipients Following Campath® Induction
Not yet reported University of Toledo Health Science Campus 55 participants Est. completion 2020-07 1 siteOther conditions: Renal TransplantView official trial listing → -
Completed NCT NCT01936519
Conversion to Everolimus From Calcineurin Inhibitor With Mycophenolic Acid: Impact on Long Term Renal Function in Liver Transplantation.
Not yet reported Milton S. Hershey Medical Center 24 participants Est. completion 2019-07-31 1 siteOther conditions: Immunosuppression, Renal FailureView official trial listing → -
Completed NCT NCT01938573
Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer
Not yet reported, Not yet reported University of Washington 21 participants Est. completion 2016-08-18 2 sites Stand-aloneOther conditions: Recurrent Bladder Carcinoma, Stage II Bladder Cancer, Stage III Bladder Cancer, Stage IV Bladder CancerView official trial listing → -
Terminated NCT NCT01939418
Phase Ib/II Trials of RAD001 in Triple Negative Metastatic Breast Cancer
Not yet reported, Not yet reported National Cancer Center, Korea 23 participants Est. completion 2017-07-30 1 siteOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT01946529
Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors
Not yet reported St. Jude Children's Research Hospital 24 participants Est. completion 2026-04-09 1 siteOther conditions: Desmoplastic Small Round Cell Tumor, Ewing Sarcoma of Bone or Soft Tissue, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorView official trial listing → -
Completed NCT NCT01950819
Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM)
Not yet reported Novartis Pharmaceuticals 2037 participants Est. completion 2018-01-17 184 sitesChronic kidney disease Other conditions: End Stage Renal Disease (ESRD), Hemodialysis, Renal Replacement Therapy, Renal TransplantationView official trial listing → -
Terminated NCT NCT01952847
Randomized Trial of Glutamine in Patients With Mucositis or Esophagitis
Not yet reported M.D. Anderson Cancer Center 77 participants Est. completion 2021-03-03 1 siteOther conditions: Advanced CancersView official trial listing → -
Status unknown NCT NCT01954693
A Study of Everolimus in the Treatment of Neurocognitive Problems in Tuberous Sclerosis
Not yet reported Cardiff University 48 participants Est. completion 2018-08-06 1 siteOther conditions: Tuberous SclerosisView official trial listing → -
Completed NCT NCT01958190
Study Comparing in Livertransplantation Recipients With Tacrolimus Alone Versus Tacrolimus&Sirolimus
Not yet reported Foundation for Liver Research 196 participants Est. completion 2021-05-20 3 sites Stand-aloneOther conditions: Liver DiseaseView official trial listing → -
Status unknown NCT NCT01960829
Everolimus in Selected Patients With Metastatic Melanoma: Efficacy and Safety Study
Not yet reported Peking University Cancer Hospital & Institute 60 participants 1 siteOther conditions: Melanoma, TOR Serine-Threonine Kinases, Neoplasm MetastasisView official trial listing → -
Terminated NCT NCT01962896
A Phase II Study of Sirolimus and Erlotinib in Recurrent/Refractory Germ Cell Tumors
Not yet reported Theodore Laetsch 4 participants Est. completion 2018-01-27 3 sites Stand-aloneOther conditions: Relapsed / Recurrent Germ Cell TumorsView official trial listing → -
Completed NCT NCT01964014
Once-a-day Immunosuppression(CISECON_a_day)
Not yet reported Ajou University School of Medicine 160 participants Est. completion 2015-10 7 sites Stand-aloneOther conditions: Chronic Renal DiseaseView official trial listing → -
Completed NCT NCT01971684
ICON1: Treatment Decisions and Outcomes in Pediatric Refractory ITP
Boston Children's Hospital 120 participants Est. completion 2017-04 29 sitesOther conditions: Immune ThrombocytopeniaView official trial listing → -
Completed NCT NCT01976390
Comparing Everolimus and Sirolimus in Renal Transplant Recipients
Not yet reported Ohio State University 60 participants Est. completion 2019-08-31 1 siteOther conditions: Renal FailureView official trial listing → -
Status unknown NCT NCT01981304
Effects of a rapamycIn-eluting carboNized Stent With a Completely biodEgradable polymeR Coating
University of Roma La Sapienza 50 participants Est. completion 2016-12Cardiovascular diseaseView official trial listing → -
Terminated NCT NCT01991938
Phase I Dose Escalation Study of VS-5584 in Subjects With Advanced Non-Hematologic Malignancies or Lymphoma
Not yet reported Verastem, Inc. 75 participants Est. completion 2016-12 5 sitesOther conditions: Non Hematologic Cancers, Metastatic Cancer, LymphomaView official trial listing → -
Withdrawn NCT NCT01997255
Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS)
Not yet reported Baylor College of Medicine Est. completion 2016-04 1 siteOther conditions: Sturge Weber SyndromeView official trial listing → -
Status unknown NCT NCT01998789
Everolimus Post Orthotopic Liver Transplant
Not yet reported Tomoaki Kato 50 participants Est. completion 2019-02 1 siteOther conditions: Orthotopic Liver TransplantView official trial listing → -
Suspended NCT NCT02008019
A Phase II Study of EVEROLIMUS in Patients With Primary or Relapsed Chondrosarcomas
Not yet reported Centre Leon Berard 57 participants Est. completion 2019-08 12 sitesObstructive sleep apneaView official trial listing → -
Completed NCT NCT02008877
SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)
Not yet reported, Not yet reported Sarcoma Alliance for Research through Collaboration 20 participants Est. completion 2018-07 7 sites Stand-aloneOther conditions: Malignant Peripheral Nerve Sheath Tumors (MPNST), SarcomaView official trial listing → -
Completed NCT NCT02009332
Phase 1/2 Study of ABI-009 in Nonmuscle Invasive Bladder Cancer
Not yet reported, Not yet reported Aadi Bioscience, Inc. 21 participants Est. completion 2019-12-01 2 sites Stand-aloneOther conditions: Non-muscle Invasive Bladder Cancer (NMIBC)View official trial listing → -
Status unknown NCT NCT02013089
A Pilot Study of Genomic Sequencing Guided Individualized Therapy in Gastrointestinal Cancers, GITIC Study
Not yet reported Sun Yat-sen University 50 participants Est. completion 2017-12 1 siteOther conditions: Gastrointestinal CancersView official trial listing → -
Terminated NCT NCT02013375
SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCD
Not yet reported Damiano Rondelli, MD 2 participants Est. completion 2018-09-07 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Status unknown NCT NCT02015728
Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors
Not yet reported Seattle Children's Hospital 20 participants Est. completion 2017-12 1 siteOther conditions: Recurrent Childhood Brain TumorView official trial listing → -
Completed NCT NCT02017275
Comparison of BuMA eG Based BioDegradable Polymer Stent With EXCEL Biodegradable Polymer Sirolimus-eluting Stent in "Real-World" Practice
Not yet reported Sino Medical Sciences Technology Inc. 2348 participants 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT02017860
Study to Collect and Assess Long-term Safety of Everolimus in Patients Who Are on Everolimus Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator.
Not yet reported Novartis Pharmaceuticals 4 participants Est. completion 2019-04-25 4 sitesOther conditions: NeoplasmsView official trial listing → -
Completed NCT NCT02019693
A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer
Not yet reported National Cancer Institute (NCI) 20 participants Est. completion 2021-12-17 1 siteOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT02023359
Danish Observational Study of Everolimus Plus Exemestane in Hormone Receptor (HR) Positive, Human Epidermal Growth Factor 2 (HER2) - Metastatic Breast Cancer
Novartis Healthcare A/S 7 participants Est. completion 2015-04 3 sitesOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT02023905
Everolimus With and Without Temozolomide in Adult Low Grade Glioma
Not yet reported University of California, San Francisco 27 participants Est. completion 2021-09-30 1 siteOther conditions: Low Grade Glioma, World Health Organization (WHO) Grade II Astrocytomas, Oligodendrogliomas, Mixed OligoastrocytomasView official trial listing → -
Status unknown NCT NCT02025712
Exemestane Plus Everolimus for Hormone-receptor Positive Metastatic Breast Cancer
Not yet reported Organisation for Oncology and Translational Research 35 participants 1 siteOther conditions: Hormone Receptor Positive Malignant Neoplasm of BreastView official trial listing → -
Completed NCT NCT02027870
EXCEL-II DES to Treat the Patients With de Novo Coronary Artery Lesions. (CREDIT-III)
JW Medical Systems Ltd 625 participants Est. completion 2019-11-07 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT02028364
Pet Imaging as a Biomarker in Hormone Refractory postmenopausaL Women
Not yet reported Jules Bordet Institute 55 participants Est. completion 2021-08-09 5 sitesOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT02031536
Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With Surgery
Not yet reported ECOG-ACRIN Cancer Research Group 2 participants Est. completion 2017-07-19 1 siteOther conditions: Gastrinoma, Glucagonoma, Insulinoma, Liver Metastases, Pancreatic Polypeptide Tumor, Recurrent Islet Cell Carcinoma, SomatostatinomaView official trial listing → -
Status unknown NCT NCT02036554
Evaluate Efficacy Study of Combination Therapy of Everolimus and Low Dose Tacrolimus in Renal Allograft Recipients
Not yet reported Seoul St. Mary's Hospital 234 participants Est. completion 2015-12 1 siteOther conditions: Kidney; Complications, AllograftView official trial listing → -
Withdrawn NCT NCT02038478
Allograft for Sickle Cell Disease and Thalassemia
Not yet reported University of Texas Southwestern Medical Center Est. completion 2021-05 1 site Stand-aloneOther conditions: Sickle Cell Disease and ThalassemiaView official trial listing → -
Completed NCT NCT02048384
A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 22 participants Est. completion 2019-09 2 sitesOther conditions: Metastatic Pancreatic AdenocarcinomaView official trial listing → -
Completed NCT NCT02049047
Study of Everolimus in Patients With Thymoma and Thymic Carcinoma Previously Treated With Chemotherapy
Not yet reported Armando Santoro, MD 41 participants Est. completion 2019-01 1 siteOther conditions: Thymoma and Thymic CarcinomaView official trial listing → -
Status unknown NCT NCT02055079
Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease
Not yet reported Medical University of Vienna 68 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Polycystic Kidney, Type 1 Autosomal Dominant Disease, Polycystic Kidney, Type 2 Autosomal Dominant DiseaseView official trial listing → -
Completed NCT NCT02056587
Everolimus in Patients With Metastatic Renal Cell Carcinoma Following Progression on Prior Bevacizumab Treatment
Not yet reported Kidney Cancer Research Bureau 37 participants Est. completion 2013-10 3 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT02057133
A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread
Not yet reported Eli Lilly and Company 198 participants Est. completion 2026-12 13 sitesOther conditions: Breast NeoplasmsView official trial listing → -
Completed NCT NCT02057978
EXCEL-II Stent Vesus EXCEL Stent to Treat the Patients With de Novo Coronary Artery Lesions.
JW Medical Systems Ltd 419 participants Est. completion 2019-12-25 1 siteCardiovascular disease Other conditions: Myocardial Ischemia, Coronary Disease, Heart Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Vascular DiseasesView official trial listing → -
Completed NCT NCT02061397
Safety of Simvastatin in LAM and TSC
Not yet reported, Not yet reported University of Pennsylvania 10 participants Est. completion 2019-12-13 1 site Stand-aloneOther conditions: Lymphangioleiomyomatosis, Tuberous Sclerosis ComplexView official trial listing → -
Status unknown NCT NCT02061800
CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant
Not yet reported, Not yet reported Diane George 14 participants Est. completion 2026-07 1 site Stand-aloneOther conditions: Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML), Myelodysplastic Syndrome (MDS), Juvenile Myelomonocytic Leukemia (JMML), Acute Lymphoblastic Leukemia (ALL), Lymphoma (Hodgkin's and Non-Hodgkin's)View official trial listing → -
Withdrawn NCT NCT02062892
Differentiating Everolimus Versus Sirolimus in Combination With Calcineurin Inhibitors in Kidney Transplant Patients
Not yet reported University of Colorado, Denver Est. completion 2014-06 Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT02062944
SRL (Sirolimus) Withdrawal
Not yet reported Northwestern University 21 participants Est. completion 2020-07 1 site Stand-aloneOther conditions: Acute Rejection of Liver Transplant, Effects of Immunosuppressant TherapyView official trial listing → -
Completed NCT NCT02064608
Investigating the Effects of AZD2014 Therapy Given Prior to Radical Prostatectomy in Men With High Risk Prostate Cancer
Not yet reported Cambridge University Hospitals NHS Foundation Trust 23 participants Est. completion 2018-06 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT02069093
Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer
Not yet reported Novartis Pharmaceuticals 92 participants Est. completion 2016-03 23 sitesOther conditions: Advanced Breast CancerView official trial listing → -
Completed NCT NCT02071862
Study of the Glutaminase Inhibitor CB-839 in Solid Tumors
Not yet reported Calithera Biosciences, Inc 210 participants Est. completion 2019-03 13 sitesOther conditions: Solid Tumors, Triple-Negative Breast Cancer, Non Small Cell Lung Cancer, Renal Cell Carcinoma, Mesothelioma, Fumarate Hydratase (FH)-Deficient Tumors, Succinate Dehydrogenase (SDH)-Deficient Gastrointestinal Stromal Tumors (GIST), Succinate Dehydrogenase (SDH)-Deficient Non-gastrointestinal Stromal Tumors, Tumors Harboring Isocitrate Dehydrogenase-1 (IDH1) and IDH2 Mutations, Tumors Harboring Amplifications in the cMyc GeneView official trial listing → -
Completed NCT NCT02073565
HARMONEE - Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt
Not yet reported OrbusNeich 572 participants Est. completion 2021-12 50 sites Stand-aloneOther conditions: Coronary Arteriosclerosis, Non ST Segment Elevation Acute Coronary SyndromeView official trial listing → -
Status unknown NCT NCT02076516
Pilot Evaluation Of CORACTO® (THE PILOT-SECRET TRIAL)
Not yet reported Alvimedica 100 participants Est. completion 2015-05 5 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT02077556
Effect of Everolimus on the Pharmacokinetics of Tacrolimus in Renal Transplant Patients
Not yet reported National Taiwan University Hospital 14 participants Est. completion 2019-01-15 1 siteOther conditions: Drug Interaction PotentiationView official trial listing → -
Completed NCT NCT02077933
Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors
Not yet reported Novartis Pharmaceuticals 79 participants Est. completion 2019-04-12 22 sitesOther conditions: Neoplasms, Breast Neoplasms, Kidney Neoplasms, Pancreatic Neuroendocine Neoplasms (pNETs)View official trial listing → -
Completed NCT NCT02080624
Efficacy and Safety Study of Topical Rapamycin Associated With Pulsed Dye Laser in Patients With Sturge-Weber Syndrome
Not yet reported Clinica Universidad de Navarra, Universidad de Navarra 23 participants Est. completion 2012-12 1 siteOther conditions: Sturge- Weber SyndromeView official trial listing → -
Enrolling by invitation NCT NCT02081755
Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer
Not yet reported Baylor Research Institute 336 participants Est. completion 2027-03 9 sitesOther conditions: Carcinoma, HepatocellularView official trial listing → -
Completed NCT NCT02084446
Everolimus + Very Low Tacrolimus vs Enteric-coated Mycophenolate Sodium + Low Tacrolimus in de Novo Renal Transplant
Not yet reported Ronaldo de Matos Esmeraldo, MD 120 participants Est. completion 2017-07 1 siteOther conditions: Transplantation Infection, Cytomegalovirus InfectionsView official trial listing → -
Completed NCT NCT02091531
Dual mTOR Inhibitor MLN0128 in Advanced Castration-Resistant Prostate Cancer (CRPC) Patients
Not yet reported Memorial Sloan Kettering Cancer Center 9 participants Est. completion 2018-10 1 siteOther conditions: Metastatic Castration-Resistant Prostate CancerView official trial listing → -
Status unknown NCT NCT02091973
MicroRNA Expression in Everolimus-based Versus Tacrolimus-based Regimens in Kidney Transplantation
Not yet reported Chulalongkorn University 50 participants Est. completion 2015-12 1 siteOther conditions: microRNA ProfilesView official trial listing → -
Completed NCT NCT02093598
POEM STUDY: A Phase IIa Trial in Endometrial Carcinoma With Temsirolimus
Not yet reported MedSIR 10 participants Est. completion 2014-03 3 sitesOther conditions: Carcinoma, Endometrioid, mTOR ProteinView official trial listing → -
Completed NCT NCT02096107
Novartis Everolimus Transition
Not yet reported Medical University of South Carolina 60 participants Est. completion 2017-05 1 siteOther conditions: Graft Dysfunction, Interstitial FibrosisView official trial listing → -
Status unknown NCT NCT02099162
Yonsei OCT (Optical Coherence Tomography) Registry for Evaluation of Efficacy and Safety of Coronary Stenting
Yonsei University 3000 participants Est. completion 2022-07 1 siteCardiovascular disease Other conditions: Ischemic Heart DiseaseView official trial listing → -
Terminated NCT NCT02102997
Deutsches Dual Therapy Stent Register
OrbusNeich 130 participants Est. completion 2017-11 1 siteCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT02105766
Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 56 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Sickle Cell Disease, Thalassemia, Stem Cell Transplantation, Graft vs Host DiseaseView official trial listing → -
Completed NCT NCT02106507
ARN 509 Plus Everolimus in Men With Progressive Metastatic Castration-Resistant Prostate Cancer After Treatment With Abiraterone Acetate
Not yet reported Memorial Sloan Kettering Cancer Center 9 participants Est. completion 2021-06-28 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT02109744
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients
Not yet reported, Not yet reported University of Rochester 27 participants Est. completion 2022-01-01 1 siteOther conditions: Acute Myelogenous LeukemiaView official trial listing → -
Status unknown NCT NCT02109913
Analysis of Tumor Tissue and Circulating Genetic Material in the Blood to Obtain Further Insight in the Effectiveness of Everolimus When Combined With Exemestane
Not yet reported Amsterdam UMC, location VUmc 175 participants Est. completion 2021-01 28 sitesOther conditions: Hormone Receptor Positive Malignant Neoplasm of Breast, Metastatic Breast CancerView official trial listing → -
Terminated NCT NCT02110069
A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular Tumors
Not yet reported Boston Children's Hospital 4 participants Est. completion 2020-10-27 7 sites Stand-aloneOther conditions: Kaposiform Hemangioendothelioma (KHE), Kasabach-Merritt Syndrome, Tufted AngiomaView official trial listing → -
Status unknown NCT NCT02112981
BioMime Vs. Xience Randomised Control Clinical Study
Not yet reported Meril Life Sciences Pvt. Ltd. 256 participants Est. completion 2019-12-01 15 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02113800
Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study
Not yet reported AIO-Studien-gGmbH 40 participants Est. completion 2020-04 1 siteOther conditions: Poorly Differentiated Malignant Neuroendocrine Carcinoma, Neuroendocrine Carcinoma, Grade 3, Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3, Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma] That Switched to G3, Neuroendocrine Tumor, Grade 3 and Disease Progression as Measured by Response Evaluation Criteria in Solid Tumors (RECIST 1.1.)View official trial listing → -
Completed NCT NCT02115113
REnal Function in Liver Transplantation: Everolimus With Calcineurin Inhibitor (CNI)-Sparing sTrategy
Not yet reported Novartis Pharmaceuticals 78 participants Est. completion 2016-09-30 14 sitesOther conditions: Liver TransplantationView official trial listing → -
Completed NCT NCT02117596
Calcineurin Inhibitor Based Immunosuppression Withdrawal
Not yet reported Pediatric Nephrology of Alabama 52 participants Est. completion 2012-11 4 sitesOther conditions: Renal TransplantView official trial listing → -
Completed NCT NCT02120469
Eribulin Mesylate and Everolimus in Treating Patients With Triple-Negative Metastatic Breast Cancer
Not yet reported City of Hope Medical Center 27 participants Est. completion 2020-03-03 3 sitesOther conditions: Estrogen Receptor Negative, HER2/Neu Negative, Progesterone Receptor-negative, Stage IV Breast Cancer, Triple-negative Breast CarcinomaView official trial listing → -
Completed NCT NCT02123823
BI 836845 in Estrogen Receptor Positive Metastatic Breast Cancer
Not yet reported Boehringer Ingelheim 164 participants Est. completion 2021-12-14 38 sitesOther conditions: NeoplasmsView official trial listing → -
Terminated NCT NCT02123966
An Open Label Phase II Trial of Topical Sirolimus for the Treatment of Refractory Oral Chronic Graft-versus-Host-Disease
Not yet reported Dana-Farber Cancer Institute 10 participants Est. completion 2016-05 2 sites Stand-aloneObstructive sleep apnea Other conditions: Chronic Graft-versus-Host-DiseaseView official trial listing → -
Completed NCT NCT02125084
Enzalutamide Plus Everolimus in Men With Metastatic Castrate-Resistant Prostate Cancer
Not yet reported SCRI Development Innovations, LLC 38 participants Est. completion 2021-05-03 5 sitesOther conditions: Prostate CancerView official trial listing → -
Withdrawn NCT NCT02126527
Auranofin and Sirolimus in Treating Patients With Advanced Solid Tumors or Recurrent Non-Small Cell Lung Cancer
Not yet reported Mayo Clinic 1 site Stand-aloneOther conditions: Recurrent Non-small Cell Lung Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Status unknown NCT NCT02127138
The Study of Active Transfer of Plaque Technique for Unprotected Distal Left Main Bifurcation Lesions
Not yet reported Beijing Anzhen Hospital 316 participants Est. completion 2021-12 1 site Stand-aloneOther conditions: Coronary Heart DiseaseView official trial listing → -
Status unknown NCT NCT02133287
To Evaluate The Safety and Efficacy of 'AVI' Stent Comparing With Firebird2® For Treating Coronary Revascularization
Not yet reported Beijing AmsinoMed Medical Device Co., Ltd 2000 participants Est. completion 2022-11 1 siteOther conditions: Ischemic Heart Disease, Myocardial Ischemia, Coronary Disease, Acute Coronary SyndromeView official trial listing → -
Terminated NCT NCT02134288
Belatacept for Renal Transplant Recipients With Delayed Graft Function
Not yet reported Ohio State University 8 participants Est. completion 2019-01-18 1 siteOther conditions: Delayed Graft FunctionView official trial listing → -
Completed NCT NCT02134899
The Efficacy of Everolimus in Reducing Total Native Kidney Volume in Polycystic Kidney Disease Transplanted Recipients
Not yet reported Assistance Publique - Hôpitaux de Paris 3 participants Est. completion 2017-11-11 1 siteOther conditions: Autosomal Dominant Polycystic Kidney DiseaseView official trial listing → -
Completed NCT NCT02137239
Regimen Optimization Study
Not yet reported Bristol-Myers Squibb 58 participants Est. completion 2019-05-02 20 sitesOther conditions: Kidney TransplantationView official trial listing → -
Terminated NCT NCT02137837
S1222 Trial (Everolimus, Anastrozole and Fulvestrant) in Post-Menopausal Stage IV Breast Cancer
Not yet reported SWOG Cancer Research Network 37 participants Est. completion 2019-12-31 223 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02138929
LDE225 + Everolimus in Advanced Gastroesophageal Adenocarcinoma
Not yet reported M.D. Anderson Cancer Center 25 participants Est. completion 2020-06-08 1 siteOther conditions: Esophageal CancerView official trial listing → -
Completed NCT NCT02142036
N-of-1 Trial: Actionable Target Identification in Metastatic Cancer for Palliative Systemic Therapy
Not yet reported Oslo University Hospital 50 participants Est. completion 2018-08 2 sitesOther conditions: Metastatic CancerView official trial listing → -
Completed NCT NCT02145559
A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors
Not yet reported University of Chicago 24 participants Est. completion 2018-07 1 site Stand-aloneOther conditions: Breast Neoplasms, Lung Neoplasms, Cancer of Liver, Lymphoma, Cancer of KidneyView official trial listing → -
Completed NCT NCT02152007
Topical Sirolimus for the Treatment of Pachyonychia Congenita (PC)
Not yet reported TransDerm, Inc. 15 participants Est. completion 2015-11 1 site Stand-aloneOther conditions: Pachyonychia CongenitaView official trial listing → -
Completed NCT NCT02152943
Everolimus, Letrozole and Trastuzumab in HR- and HER2/Neu-positive Patients
Not yet reported M.D. Anderson Cancer Center 37 participants Est. completion 2020-12-14 5 sitesOther conditions: Advanced Malignant Solid Neoplasm, Estrogen Receptor Positive, HER2/Neu Positive, Postmenopausal, Premenopausal, Progesterone Receptor Positive, Recurrent Breast Carcinoma, Refractory Breast Carcinoma, Refractory Hormone Receptor Positive Breast Carcinoma, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Stage IV Breast Cancer AJCC v6 and v7View official trial listing → -
Completed NCT NCT02155920
Everolimus for Children With Recurrent or Progressive Ependymoma
Not yet reported University of Texas Southwestern Medical Center 11 participants Est. completion 2023-07-14 4 sitesOther conditions: Recurrent Childhood EpendymomaView official trial listing → -
Completed NCT NCT02165007
Haploidentical Hematopoietic Stem Cell Transplantation
Not yet reported Catherine Bollard 7 participants Est. completion 2024-10 1 site Stand-aloneOther conditions: Sickle Cell-thalassemia Disease, ThalassemiaView official trial listing → -
Completed NCT NCT02166177
Safety and Efficacy Study of Regulatory T Cell Therapy in Liver Transplant Patients
Not yet reported, Not yet reported Guy's and St Thomas' NHS Foundation Trust 9 participants Est. completion 2018-01-22 1 site Stand-aloneOther conditions: End-stage Liver DiseaseView official trial listing → -
Withdrawn NCT NCT02177760
Sirolimus Prophylaxis for aGVHD in TME SCID
Not yet reported University of California, San Francisco Est. completion 2015-11 1 site Stand-aloneOther conditions: Severe Combined Immunodeficiency, Transplacental Maternal Engraftment, Stem Cell TransplantView official trial listing → -
Completed NCT NCT02183454
MASCOT - Post Marketing Registry
OrbusNeich 2500 participants Est. completion 2017-05-31 1 siteCardiovascular disease Other conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT02184416
Study Of The Impact Of Inlyta In 2nd Line On The Treatment Outcomes Of mRCC Patients Treated With Sutent In 1st Line In The Real Life Setting
Pfizer 554 participants Est. completion 2022-09-30 110 sitesOther conditions: Metastatic Renal Cell Carcinoma (mRCC)View official trial listing → -
Completed NCT NCT02187302
CRLX101(NLG207) in Combination With Bevacizumab for Metastatic Renal Cell Carcinoma (mRCC) Versus Standard of Care (SOC)
Not yet reported NewLink Genetics Corporation 115 participants Est. completion 2017-01 43 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Status unknown NCT NCT02188550
Single Arm Trial With Combination of Everolimus and Letrozole in Treatment of Platinum Resistant Relapse or Refractory or Persistent Ovarian Cancer/Endometrial Cancer
Not yet reported Sinai Hospital of Baltimore 20 participants 1 siteOther conditions: Ovarian Cancer, Endometrial CancerView official trial listing → -
Terminated NCT NCT02188719
Donor-Alloantigen-Reactive Regulatory T Cell (darTregs) in Liver Transplantation
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 15 participants Est. completion 2019-06-18 3 sitesOther conditions: Liver TransplantationView official trial listing → -
Status unknown NCT NCT02195414
NeoVas Bioresorbable Coronary Scaffold First-in-Man Study
Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 31 participants Est. completion 2019-09 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02198300
DES Versus BiOSS LIM - POLBOS II Study
Not yet reported Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland 202 participants Est. completion 2015-03 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT02201212
Everolimus for Cancer With TSC1 or TSC2 Mutation
Not yet reported Dana-Farber Cancer Institute 30 participants Est. completion 2019-06 2 sitesOther conditions: TSC1, TSC2, Tuberous Sclerosis Complex, MTORView official trial listing → -
Completed NCT NCT02205515
An Open Label, Single-Centre, Pilot Study of Everolimus With EBRT for the Treatment of mNET Liver Metastasis
Not yet reported, Not yet reported Sunnybrook Health Sciences Centre 17 participants Est. completion 2021-10 1 siteOther conditions: Carcinoma, NeuroendocrineView official trial listing → -
Status unknown NCT NCT02208128
Molecular Determinants for Therapy Response on Renal Cell Carcinoma
Not yet reported Heidelberg University 4 participants Est. completion 2018-02 1 siteOther conditions: Renal Cell CarcinomaView official trial listing → -
Status unknown NCT NCT02208791
Effects of the Quadruple Immunosuppression on Peripheral Blood Lymphocytes and Development of Anti-HLA Antibodies in Kidney Transplant
Not yet reported University of Sao Paulo General Hospital 45 participants Est. completion 2017-07 1 site Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Terminated NCT NCT02214706
Treatment of Port Wine Stains Using Pulsed Dye Laser, Erbium Yag Laser and Topical Sirolimus
Not yet reported Erasmus Medical Center 17 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Port-Wine StainView official trial listing → -
Completed NCT NCT02215720
Temsirolimus and Cetuximab in Patients With Advanced or Metastatic Solid Tumors
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 45 participants Est. completion 2016-05-04 1 siteOther conditions: Patients With Advanced or Metastatic Solid TumorsView official trial listing → -
Status unknown NCT NCT02216058
Safety and Efficacy Study of NOYA Sirolimus-Eluting Stent to Treat Coronary Artery Disease
Not yet reported Medfavour (Beijing) Medical Co., Ltd 2000 participants Est. completion 2020-06 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02216786
A Randomized Study of AZD2014 in Combination With Fulvestrant in Metastatic or Advanced Breast Cancer
Not yet reported Queen Mary University of London 333 participants Est. completion 2021-12-31 79 sitesOther conditions: Estrogen Receptor Positive Breast CancerView official trial listing → -
Completed NCT NCT02226861
Ultra-Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantation
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 24 participants Est. completion 2018-06-27 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML), Chronic Lymphocytic Leukemia (CLL), Chronic Myelogenous Leukemia (CML), MDSView official trial listing → -
Completed NCT NCT02228681
Everolimus and Letrozole or Hormonal Therapy to Treat Endometrial Cancer
Not yet reported GOG Foundation 74 participants Est. completion 2024-08-22 26 sitesOther conditions: Advanced, Persistent, or Recurrent Endometrial CancerView official trial listing → -
Status unknown NCT NCT02233049
Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 250 participants Est. completion 2018-10 1 siteOther conditions: Diffuse Intrinsic Pontine GliomaView official trial listing → -
Terminated NCT NCT02236572
Neoadj ph 2 AI Plus Everolimus in Postmenopausal Women w/ ER Pos/HER2 Neg, Low Risk Score
Not yet reported Yale University 17 participants Est. completion 2021-03-01 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02236975
First-in-man Trial Examining the Safety and Efficacy of BuMA Supreme and Resolute Integrity in Patients With de Novo Coronary Artery Stenosis
Not yet reported, Not yet reported Sino Medical Sciences Technology Inc. 168 participants Est. completion 2019-03 12 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT02238496
Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomas
Not yet reported Andrew B Lassman, MD 10 participants Est. completion 2021-02-14 2 sitesOther conditions: Brain Tumor, Recurrent, Glioblastoma, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Mixed GliomaView official trial listing → -
Completed NCT NCT02240407
Re-administration of Intramuscular AAV9 in Patients With Late-Onset Pompe Disease
Not yet reported University of Florida 2 participants Est. completion 2021-08-26 1 site Stand-aloneOther conditions: Pompe DiseaseView official trial listing → -
Completed NCT NCT02240719
Everolimus and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory Hematologic Cancer
Not yet reported University of California, Davis 20 participants Est. completion 2018-04-09 1 siteOther conditions: Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Refractory Chronic Lymphocytic Leukemia, Multiple MyelomaView official trial listing → -
Completed NCT NCT02241564
Malignancies in Transplanted Patients
Uppsala University 95 participants Est. completion 2017-06 1 siteOther conditions: NeoplasmsView official trial listing → -
Completed NCT NCT02246127
Sequentiality of Everolimus and STZ-5FU in Advanced Pancreatic Neuroendocrine Tumor
Not yet reported Grupo Espanol de Tumores Neuroendocrinos 141 participants Est. completion 2021-07-12 37 sitesOther conditions: Neuroendocrine TumorsView official trial listing → -
Completed NCT NCT02248012
Everolimus and Temozolomide in Advanced Gastroenteropancreatic Neuroendocrine Carcinoma (G3)
Not yet reported Haukeland University Hospital 38 participants Est. completion 2019-12-01 1 siteOther conditions: Neuroendocrine CarcinomaView official trial listing → -
Completed NCT NCT02248571
Patient Preference for Everolimus in Combination With Exemestane or Capecitabine in Combination With Bevacizumab
Not yet reported iOMEDICO AG 85 participants Est. completion 2017-09-30 1 siteOther conditions: Breast Cancer Recurrent, HER2/Neu-negative Carcinoma of Breast, Hormone Receptor Positive Malignant Neoplasm of BreastView official trial listing → -
Completed NCT NCT02251938
A Phase IIIb, Multinational, Multicenter, Open-Label Extension Study Assessing the Long-Term Safety of PRN Intravitreal Injections of DE-109 in Subjects With Non-Infectious Uveitis of the Posterior Segment of the Eye Who Have Participated in the SAKURA Development Program
Not yet reported Santen Inc. 60 participants Est. completion 2017-11-27 25 sites Stand-aloneOther conditions: Non-Infectious Uveitis of the Posterior Segment of the EyeView official trial listing → -
Terminated NCT NCT02254239
Everolimus and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma
Not yet reported Mayo Clinic 10 participants Est. completion 2018-12-12 1 siteOther conditions: Recurrent Hodgkin Lymphoma, Refractory Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT02254668
Intracoronary Analysis of Cardiac Allograft Vasculopathy by Means of Optical Coherence Tomography
Not yet reported University of Zurich 278 participants Est. completion 2023-02 1 siteOther conditions: Intimal Proliferation, ImmunosuppressionView official trial listing → -
Completed NCT NCT02258451
Study of Radium-223 Dichloride in Combination With Exemestane and Everolimus Versus Placebo in Combination With Exemestane and Everolimus in Subjects With Bone Predominant HER2 Negative Hormone Receptor Positive Metastatic Breast Cancer
Not yet reported Bayer 283 participants Est. completion 2022-10-28 92 sitesOther conditions: Breast NeoplasmsView official trial listing → -
Completed NCT NCT02263313
EGO-COMBO Clinical End-point Extension Study Beyond 36 Months
The University of Hong Kong 59 participants Est. completion 2014-09 1 siteOther conditions: Coronary RestenosisView official trial listing → -
Completed NCT NCT02264665
OPALINE : A Study Of Morbidity And Mortality At 2 Years
Pfizer 144 participants Est. completion 2019-11-18 35 sitesOther conditions: Pancreatic Neuroendocrine Tumor, Well Differentiated and ProgressiveView official trial listing → -
Terminated NCT NCT02269670
Phase II Study of Everolimus Beyond Progression
Not yet reported Emory University 3 participants Est. completion 2021-01-25 3 sitesOther conditions: Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Cancer, Progesterone Receptor-positive Breast Cancer, Recurrent Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast CancerView official trial listing → -
Terminated NCT NCT02273752
Pharmacokinetically Guided Everolimus in Patients With Breast Cancer, Pancreatic Neuroendocrine Tumors, or Kidney Cancer
Not yet reported Emory University 2 participants Est. completion 2015-12 2 sitesOther conditions: Estrogen Receptor-positive Breast Cancer, Gastrinoma, Glucagonoma, HER2-negative Breast Cancer, Insulinoma, Mucositis, Oral Complications, Pancreatic Polypeptide Tumor, Progesterone Receptor-positive Breast Cancer, Recurrent Breast Cancer, Recurrent Islet Cell Carcinoma, Recurrent Renal Cell Cancer, Somatostatinoma, Stage III Renal Cell Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer, Stage IV Renal Cell CancerView official trial listing → -
Status unknown NCT NCT02279758
A Pilot Study of Metformin Treatment in Patients With Well-differentiated Neuroendocrine Tumors
Not yet reported Instituto do Cancer do Estado de São Paulo 30 participants 1 siteOther conditions: Well-differentiated Neuroendocrine TumorsView official trial listing → -
Terminated NCT NCT02282904
Haploidentical Transplant for People With Chronic Granulomatous Disease Using Post Transplant Cyclophosphamide
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 7 participants Est. completion 2019-12-10 1 site Stand-aloneOther conditions: Chronic Granulomatous DiseaseView official trial listing → -
Completed NCT NCT02283658
Everolimus and Letrozole in Treating Patients With Recurrent Hormone Receptor Positive Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer
Not yet reported Mayo Clinic 20 participants Est. completion 2018-06-21 2 sitesOther conditions: Ovarian Endometrioid Adenocarcinoma, Ovarian Seromucinous Carcinoma, Ovarian Serous Cystadenocarcinoma, Ovarian Serous Surface Papillary Adenocarcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Ovarian Germ Cell Tumor, Recurrent Primary Peritoneal Carcinoma, Undifferentiated Ovarian CarcinomaView official trial listing → -
Completed NCT NCT02291913
Everolimus Combined With Anti-estrogen Therapy in Hormone-Receptor-Positive HER-2 Negative Advanced Breast Cancer
Not yet reported SCRI Development Innovations, LLC 48 participants Est. completion 2019-01-31 8 sitesOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT02294006
Activity and Safety of Everolimus+Octreotide LAR+Metformin in Advanced Pancreatic Well-differentiated NETs
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 26 participants Est. completion 2021-10 1 siteOther conditions: Well Differentiated Pancreatic Endocrine TumorView official trial listing → -
Completed NCT NCT02296749
Bioavailability Study of Sirolimus Tablets 2 mg Under Fasting Condition
Not yet reported Dr. Reddy's Laboratories Limited 60 participants Est. completion 2010-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02296762
Bioavailability Study of Sirolimus Tablets 2 mg Under Fed Condition
Not yet reported Dr. Reddy's Laboratories Limited 36 participants Est. completion 2010-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02305472
NeoVas Bioresorbable Coronary Scaffold Registry Study
Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 825 participants Est. completion 2020-09 27 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT02305485
NeoVas Bioresorbable Coronary Scaffold Randomized Controlled Trial
Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 560 participants Est. completion 2020-06 27 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02305810
A Biological Prospective Study in Patients With Metastatic Pancreatic NETs Treated With Everolimus
Not yet reported European Institute of Oncology 54 participants Est. completion 2018-06 1 siteOther conditions: Pancreatic Neuroendocrine Tumour MetastaticView official trial listing → -
Terminated NCT NCT02306135
Identifying Mechanisms of Resistance to mTOR Inhibitors in Cancer
Dartmouth-Hitchcock Medical Center 2 participants Est. completion 2016-03 1 siteOther conditions: CancerView official trial listing → -
Status unknown NCT NCT02313051
Everolimus trIal for Advanced prememopausaL Breast Cancer Patients
Not yet reported Chinese Academy of Medical Sciences 200 participants Est. completion 2017-12 1 siteOther conditions: Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT02314312
Efficacy and Safety of Everolimus in de Novo Kidney Transplant Recipients of ECD or AKI Donors
Not yet reported Mahidol University 48 participants Est. completion 2015-06Other conditions: Transplantation of Kidney, Expanded Criteria Donor, ECDView official trial listing → -
Terminated NCT NCT02315625
Study of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery
Not yet reported National Cancer Institute (NCI) 16 participants Est. completion 2019-05-22 1 siteOther conditions: Neuroendocrine Tumors, Neuroendocrine Carcinoma, Neuroendocrine Neoplasms, Carcinoma, Neuroendocrine, Neuroendocrine Tumors of the Gastrointestinal Tract and PancreasView official trial listing → -
Active, not recruiting NCT NCT02321501
Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer
Not yet reported M.D. Anderson Cancer Center 37 participants Est. completion 2026-12-31 1 siteOther conditions: ALK Positive, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, ROS1 Gene Rearrangement, Stage IIIB Lung Non-Small Cell Cancer AJCC v7, Stage IV Lung Non-Small Cell Cancer AJCC v7View official trial listing → -
Completed NCT NCT02328781
Prospective Evaluation of Safety and Efficacy Vertebral Drug-eluting Stent System
Not yet reported Zhongrong Miao 101 participants Est. completion 2016-11-25 1 siteOther conditions: Vertebrobasilar InsufficiencyView official trial listing → -
Completed NCT NCT02328963
Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporine Versus an Immunosuppressive Regimen With Mycophenolic Acid and Standard Dose of Cyclosporine A
Not yet reported University Hospital, Bordeaux 186 participants Est. completion 2018-10-10 9 sitesOther conditions: Transplantation Infection, Cytomegalovirus InfectionView official trial listing → -
Completed NCT NCT02329808
Clinical Validation of a Dried Blood Spot Method for Analysis of Immunosuppressives and Antifungals in Pediatrics
Radboud University Medical Center 93 participants Est. completion 2021-12-03 1 siteOther conditions: Hematologic Diseases, Oncology Problem, Kidney Diseases, Transplantation InfectionView official trial listing → -
Completed NCT NCT02332902
Everolimus for Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis1 CRAD001CUS232T
Not yet reported The University of Texas Health Science Center, Houston 24 participants Est. completion 2016-03 1 siteOther conditions: Neurofibromatosis 1View official trial listing → -
Completed NCT NCT02333565
Combination of Everolimus and Octreotide LAR in Aggressive Recurrent Meningiomas
Not yet reported Assistance Publique Hopitaux De Marseille 20 participants Est. completion 2023-05-24 1 siteOther conditions: Recurrent Meningiomas, Resistant MeningiomasView official trial listing → -
Completed NCT NCT02334488
Study Evaluating the Benefit of Two Immunosuppressive Strategies on Renal Function
Not yet reported Poitiers University Hospital 329 participants Est. completion 2020-07-03 14 sitesChronic kidney diseaseView official trial listing → -
Terminated NCT NCT02338570
Outcome-related Factors in Patients With Metastatic Renal Cell Carcinoma Treated With Everolimus (ORCHIDEE)
Not yet reported Mario Negri Institute for Pharmacological Research 31 participants Est. completion 2018-02 8 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT02338609
Long-term Monitoring of Growth and Development of Pediatric Patients Previously Treated With Everolimus
Not yet reported Novartis Pharmaceuticals 15 participants Est. completion 2023-12-18 6 sitesOther conditions: Growth and DevelopmentView official trial listing → -
Completed NCT NCT02343718
Vinblastine and Temsirolimus in Pediatrics With Recurrent or Refractory Lymphoma or Solid Tumours Including CNS Tumours
Not yet reported Canadian Cancer Trials Group 7 participants Est. completion 2019-01-16 6 sitesOther conditions: Recurrent Lymphoma, Refractory Lymphoma, Solid Tumours, Central Nervous SystemView official trial listing → -
Completed NCT NCT02344550
Study of GnRH-A [Leuprorelin(Lorelin Depot] Plus Leterozole +/- Everolimus for Premenopausal Women With Metastatic Breast Cancer
Not yet reported Asan Medical Center 137 participants Est. completion 2018-10 1 siteOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT02352844
Everolimus in Patients With Advanced Solid Malignancies With TSC1, TSC2, NF1, NF2, or STK11 Mutations
Not yet reported Washington University School of Medicine 12 participants Est. completion 2017-08-15 1 siteOther conditions: Solid Malignancy, Solid TumorView official trial listing → -
Completed NCT NCT02356159
Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation
Not yet reported, Not yet reported National Cancer Institute (NCI) 34 participants Est. completion 2025-03-25 2 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Acute Leukemia, Multiple MyelomaView official trial listing → -
Completed NCT NCT02357342
Sirolimus Versus Anti-Vascular Endothelial Growth Factor (antiVEGF) for Wet AMD
Not yet reported Maturi, Raj K., M.D., P.C. 40 participants Est. completion 2017-01 1 site Stand-aloneOther conditions: Age-Related Macular DegenerationView official trial listing → -
Completed NCT NCT02360020
The XLIMUS-DES in Very Complex Lesions
Not yet reported Clinica Mediterranea 200 participants Est. completion 2016-05 1 siteOther conditions: Coronary Atherosclerosis Due to Calcified Coronary Lesion, Chronic Total Occlusion of Coronary ArteryView official trial listing → -
Status unknown NCT NCT02360423
Safety and Efficacy of the CRE8 Stent for the Treatment of De Novo Coronary Artery Lesions
Not yet reported CID S.p.A. 430 participants Est. completion 2021-04 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT02360709
Safety and Efficacy of the CRE8 Sirolimus-Eluting Stent for the Treatment of De Novo Coronary Artery Lesions
CID S.p.A. 800 participants Est. completion 2021-04 1 siteCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT02365415
Systemic Rapamycin (Sirolimus) to Prevent In-Stent Restenosis Following Pulmonary Artery Stent Placement
Not yet reported Boston Children's Hospital Est. completion 2018-04 1 site Stand-aloneOther conditions: Peripheral Pulmonary Stenosis, In-stent StenosisView official trial listing → -
Terminated NCT NCT02372227
A Phase 1 Dose Escalation Study of VS-5584 Administered in Combination With VS-6063, in Subjects With Relapsed Malignant Mesothelioma
Not yet reported Verastem, Inc. 21 participants Est. completion 2015-10 4 sitesOther conditions: Relapsed Malignant MesotheliomaView official trial listing → -
Completed NCT NCT02376985
Evaluation of Oral Care to Prevent Oral Mucositis in ER Positive MBC Patients Treated With Everolimus: Phase 3 RCT
Not yet reported Comprehensive Support Project for Oncology Research 174 participants Est. completion 2018-10-16 1 siteOther conditions: Breast CancerView official trial listing → -
Withdrawn NCT NCT02384629
PCI With AXXESS Biolimus A9 Eluting Bifurcation Stent in Treating Coronary Artery Bifurcation Disease
Not yet reported Yonsei University Est. completion 2017-12 Stand-aloneOther conditions: Coronary Bifurcation LesionsView official trial listing → -
Completed NCT NCT02384837
Effect of TCFA on Neointimal Coverage After PCI at 9 Months Follow-up
General Hospital of Chinese Armed Police Forces 33 participants Est. completion 2016-11 1 siteOther conditions: Unrecognized ConditionView official trial listing → -
Completed NCT NCT02385279
Study Comparing the MiStent SES Versus the XIENCE EES Stent
Not yet reported ECRI bv 1398 participants Est. completion 2021-02-04 20 sites Stand-aloneOther conditions: Coronary StenosisView official trial listing → -
Active, not recruiting NCT NCT02389309
Dasatinib, Temsirolimus, and Cyclophosphamide in Treating Patients With Advanced, Recurrent, or Refractory Solid Tumors
Not yet reported M.D. Anderson Cancer Center 14 participants Est. completion 2027-10-31 1 siteOther conditions: Advanced Malignant Solid Neoplasm, Recurrent Brain Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory Brain NeoplasmView official trial listing → -
Completed NCT NCT02389946
Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Not yet reported Biotronik, Inc. 1334 participants Est. completion 2021-03 92 sites Stand-aloneCardiovascular disease Other conditions: Atherosclerosis, Coronary, Myocardial Ischemia, Ischemic Heart Disease, Acute Coronary Syndrome, Angina PectorisView official trial listing → -
Active, not recruiting NCT NCT02397083
Levonorgestrel-Releasing Intrauterine System With or Without Everolimus in Treating Patients With Atypical Hyperplasia or Stage IA Grade 1 Endometrial Cancer
Not yet reported M.D. Anderson Cancer Center 102 participants Est. completion 2028-09-30 18 sitesOther conditions: Atypical Endometrial Hyperplasia, FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid AdenocarcinomaView official trial listing → -
Status unknown NCT NCT02398955
Biomime Stent in All-comers PCI Patients Registry
Azienda Ospedaliero Universitaria Maggiore della Carita 250 participants Est. completion 2016-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT02400632
MagicTouch Sirolimus Drug Coated Balloon Catheter for the Treatment of Coronary Lesions
Not yet reported Scitech Produtos Medicos SA 60 participants Est. completion 2019-12-30 3 sitesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT02404051
Fulvestrant and EVerolimus Plus EXemestane in Metastatic Breast Cancer
Not yet reported Consorzio Oncotech 745 participants Est. completion 2019-01 41 sitesOther conditions: Metastatic Breast Cancer, Breast Cancer, Hormone Receptor Positive Tumor, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast, Locally Advanced Malignant NeoplasmView official trial listing → -
Completed NCT NCT02406326
An Evaluation of BioMime™ - Sirolimus Eluting Coronary Stent in a Multi- Centre Study.
Meril Life Sciences Pvt. Ltd. 250 participants Est. completion 2016-12-27 11 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT02407054
A Study of Enzalutamide and LY3023414 in Men With Prostate Cancer
Not yet reported Eli Lilly and Company 142 participants Est. completion 2020-04-16 36 sitesOther conditions: Prostate Cancer MetastaticView official trial listing → -
Completed NCT NCT02407509
Phase I Trial of VS-6766 Alone and in Combination With Everolimus
Not yet reported Royal Marsden NHS Foundation Trust 104 participants Est. completion 2025-10-15 3 sitesOther conditions: Solid Tumours, Multiple Myeloma, Lung Cancer, Ovarian CancerView official trial listing → -
Terminated NCT NCT02411084
Study of BEGEDINA® vs "Conventional Treatment" for Treating Steroid-Resistant Acute GvHD
Not yet reported Adienne SA 36 participants Est. completion 2017-07-31 27 sitesOther conditions: Graft vs Host DiseaseView official trial listing → -
Status unknown NCT NCT02415452
Researches of Retinal Artery Lesions and Acute Coronary Syndrome
Capital Medical University 660 participants Est. completion 2018-01Other conditions: Acute Coronary SyndromeView official trial listing → -
Completed NCT NCT02420613
Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma
Not yet reported M.D. Anderson Cancer Center 18 participants Est. completion 2025-03-28 1 siteOther conditions: Diffuse Intrinsic Pontine GliomaView official trial listing → -
Completed NCT NCT02423915
Fucosylated T Cells for Graft Versus Host Disease (GVHD) Prevention
Not yet reported M.D. Anderson Cancer Center 5 participants Est. completion 2020-10-06 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT02423954
Study of Nivolumab Plus Chemotherapy in Patients With Advanced Cancer (NivoPlus)
Not yet reported, Not yet reported Western Regional Medical Center 33 participants Est. completion 2017-11-01 1 siteOther conditions: Advanced Cancer, Pancreatic Cancer, Renal Cell Cancer, Non Small Cell Lung Cancer, Colorectal Carcinoma, Endometrial, UterineView official trial listing → -
Completed NCT NCT02428296
Study of Sirolimus Therapy for Segmental Overgrowth Caused by Somatic PI3K Activation
Not yet reported National Human Genome Research Institute (NHGRI) 39 participants Est. completion 2018-02-14 1 site Stand-aloneOther conditions: PIK3CA-Related Overgrowth Spectrum (PROS), Growth Disorder, GeneticsView official trial listing → -
Completed NCT NCT02429869
Impact of Everolimus on HIV Persistence Post Kidney or Liver Transplant
Not yet reported University of California, San Francisco 10 participants Est. completion 2018-01-31 1 siteOther conditions: HIV, Kidney Transplant, Liver TransplantView official trial listing → -
Completed NCT NCT02429973
Trial With Gemcitabine and Rapamycin in Second Line of Metastatic Osteosarcoma
Not yet reported Broto, Javier Martín, M.D. 33 participants Est. completion 2015-04Obstructive sleep apneaView official trial listing → -
Status unknown NCT NCT02430363
Evaluation Of The Treatment Effectiveness Of Glioblastoma / Gliosarcoma Through The Suppression Of The PI3K/Akt Pathway In Compared With MK-3475
Not yet reported, Not yet reported Medical Research Council 58 participants Est. completion 2018-06 13 sitesOther conditions: GlioblastomaView official trial listing → -
Completed NCT NCT02440789
Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)
Not yet reported, Not yet reported Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections 32 participants Est. completion 2018-02-01 10 sites Stand-aloneOther conditions: HIV-1 InfectionView official trial listing → -
Completed NCT NCT02441543
Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus
Istituto Clinico Humanitas 45 participants Est. completion 2018-05 1 siteOther conditions: SOLID TUMORView official trial listing → -
Completed NCT NCT02443818
Sirolimus Effect on Hypertrophic Syndromes Related Gene PIK3CA
Not yet reported Centre Hospitalier Universitaire Dijon 16 participants Est. completion 2016-11 11 sitesOther conditions: Segmental Overgrowth Disorders Due to PIK3CAView official trial listing → -
Completed NCT NCT02444390
Molecular Alterations Associated With Resistance to Endocrine Therapy and Impacting Treatment With mTOR Inhibitor
Not yet reported UNICANCER 150 participants Est. completion 2022-07-01 12 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT02448524
Clinical Trial on the Efficacy and Safety of Sirolimus-Eluting Stent (MiStent® System)
Not yet reported Micell Technologies 428 participants Est. completion 2022-11 16 sites Stand-aloneOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT02449538
Study to Evaluate the Safety and Efficacy of Everolimus, in Subjects With PIK3CA Amplification, PTEN Loss and PIK3CA Mutation Refractory Solid Tumors
Not yet reported Samsung Medical Center 10 participants Est. completion 2016-08 1 siteOther conditions: Solid TumorView official trial listing → -
Completed NCT NCT02449564
The Pilot Study Evaluate the Safety and Efficacy of Sirolimus in Patients With PIK3CA Mutation and/or PIK3CA Amplification Refractory Solid Tumors
Not yet reported Samsung Medical Center 5 participants Est. completion 2017-11-03 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Status unknown NCT NCT02450175
Etiology of the Platelet-Cancer Metastatic Pathway - A Study of Inflammatory Markers, Platelet Characteristics and Metastatic Surrogates in Cancer Patients and Controls
Not yet reported Sinai Hospital of Baltimore 50 participants Est. completion 2016-06 1 siteOther conditions: NeoplasmView official trial listing → -
Completed NCT NCT02451696
A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD
Not yet reported NYU Langone Health 15 participants Est. completion 2017-12-28 1 siteOther conditions: Epilepsy, Tuberous Sclerosis Complex, Focal Cortical DysplasiaView official trial listing → -
Completed NCT NCT02454478
Study of Lenvatinib in Combination With Everolimus in Participants With Unresectable Advanced or Metastatic Renal Cell Carcinoma (RCC)
Not yet reported Eisai Co., Ltd. 7 participants Est. completion 2017-05-29 3 sitesOther conditions: Carcinoma, Renal CellView official trial listing → -
Completed NCT NCT02456857
Liposomal Doxorubicin, Bevacizumab, and Everolimus in Patients With Locally Advanced TNBC With Tumors Predicted Insensitive to Standard Chemotherapy; A Moonshot Initiative
Not yet reported M.D. Anderson Cancer Center 17 participants Est. completion 2023-05-24 1 siteOther conditions: Invasive Breast Carcinoma, Triple-Negative Breast CarcinomaView official trial listing → -
Terminated NCT NCT02479490
PRednisone Plus EVerolimus in Patients With Metastatic Renal Cell Cancer After Failure of VEGFR -TKI
Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 8 participants Est. completion 2017-09 4 sitesOther conditions: Metastatic Renal CancerView official trial listing → -
Completed NCT NCT02481453
Rapamycine vs Placebo for the Treatment of Inclusion Body Myositis
Not yet reported, Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 44 participants Est. completion 2018-01-22 1 siteOther conditions: Inclusion Body Myositis (IBM)View official trial listing → -
Completed NCT NCT02482974
Conversion From Sirolimus to Everolimus in the Maintenance Treatment of Liver Transplant Recipients
Ege University 66 participants Est. completion 2016-07 1 siteOther conditions: Liver Transplant RecipientsView official trial listing → -
Completed NCT NCT02484664
COLA: A Pilot Clinical Trial of COX-2 Inhibition in LAM and TSC
Not yet reported Brigham and Women's Hospital 12 participants Est. completion 2018-11-19 1 siteOther conditions: Lymphangioleiomyomatosis (LAM)View official trial listing → -
Completed NCT NCT02486315
Treatment of Coronary ARtery bIfurcation Narrowing by AXxess Stent Implantation
Clinica Mediterranea 326 participants Est. completion 2015-06Cardiovascular diseaseView official trial listing → -
Completed NCT NCT02487485
Examining the Impact of Sirolimus on Ketamine's Antidepressant Effects
Not yet reported Yale University 23 participants Est. completion 2020-01 2 sites Stand-aloneOther conditions: DepressionView official trial listing → -
Status unknown NCT NCT02493465
Effects of Everolimus in Left Ventricular Hypertrophy After Conversion From Azathioprine: A Pilot Study
Not yet reported Instituto de Urologia e Nefrologia 50 participants Est. completion 2017-07 1 siteOther conditions: Left Ventricular HypertrophyView official trial listing → -
Completed NCT NCT02494570
A Phase 2 Study of Nab-sirolimus (ABI-009) in Patients With Advanced Malignant PEComa
Not yet reported Aadi Bioscience, Inc. 34 participants Est. completion 2022-04 9 sites Stand-aloneOther conditions: Malignant PEComaView official trial listing → -
Status unknown NCT NCT02494895
Ticagrelor Monotherapy After 3 Months in the Patients Treated With New Generation Sirolimus Stent for Acute Coronary Syndrome (TICO Study)
Not yet reported Yonsei University 3056 participants Est. completion 2023-05 1 siteOther conditions: Acute Coronary SyndromeView official trial listing → -
Status unknown NCT NCT02496169
Prospective multicEntric NonranDomized Registry
Not yet reported Eucatech AG 400 participants Est. completion 2017-12Cardiovascular diseaseView official trial listing → -
Completed NCT NCT02502851
The Comparison of Strategies to PREPARE Severely CALCified Coronary Lesions Trial (PREPARE-CALC)
Not yet reported Segeberger Kliniken GmbH 200 participants Est. completion 2019-10 1 siteOther conditions: Coronary Atherosclerosis Due to Severely Calcified Coronary LesionView official trial listing → -
Completed NCT NCT02504307
OCT Evaluation 3 Months After Sirolimus Eluting Stent Implantation
Not yet reported Scitech Produtos Medicos SA 36 participants Est. completion 2017-09 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT02504892
Everolimus Therapy in People With Birt-Hogg-Dube Syndrome (BHD)-Associated Kidney Cancer or Sporadic Chromophobe Renal Cancer
Not yet reported National Cancer Institute (NCI) 3 participants Est. completion 2018-04-17 1 siteOther conditions: Renal Cancer, Birt-Hogg-Dube SyndromeView official trial listing → -
Completed NCT NCT02505893
Minimal Islet Transplant at Diabetes Onset
Not yet reported Ospedale San Raffaele 6 participants Est. completion 2023-12 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT02508714
Bioresorbable Polymer ORSIRO Versus Durable Polymer RESOLUTE ONYX Stents
Not yet reported Thorax Centrum Twente 2470 participants Est. completion 2019-03 7 sitesCardiovascular disease Other conditions: Angina Pectoris, Unstable Angina Pectoris, Acute Coronary Syndrome, Coronary Stenosis, Coronary RestenosisView official trial listing → -
Completed NCT NCT02509468
suPERficial Slow-flow Vascular malFORMations Treated With sirolimUS
Not yet reported University Hospital, Tours 63 participants Est. completion 2019-03 12 sites Stand-aloneOther conditions: Vascular MalformationView official trial listing → -
Completed NCT NCT02511639
Maintenance Aromatase Inhibitors (AIs)+ Everolimus vs AIs in Hormone Receptor Positive Metastatic Breast Cancer Patients
Not yet reported Istituto Oncologico Veneto IRCCS 110 participants Est. completion 2020-07-31 16 sitesOther conditions: Breast Cancer MetastaticView official trial listing → -
Completed NCT NCT02512003
Pilot Study of the Fantom Bioresorbable Scaffold (FANTOM I)
Not yet reported REVA Medical, Inc. 7 participants Est. completion 2020-04 2 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT02513303
Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes
Not yet reported Vascular Therapies, Inc. 269 participants Est. completion 2021-06 4 sites Stand-aloneOther conditions: Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD, Chronic Kidney Failure, Complication of Hemodialysis, Vascular Access Complication, Arteriovenous FistulaView official trial listing → -
Completed NCT NCT02514824
MLN0128 in Recurrent/Metastatic Merkel Cell Carcinoma
Not yet reported, Not yet reported Dana-Farber Cancer Institute 9 participants Est. completion 2017-06 1 siteOther conditions: Merkel Cell CarcinomaView official trial listing → -
Completed NCT NCT02517918
Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma
Not yet reported Institut Bergonié 23 participants Est. completion 2021-11-16 3 sites Stand-aloneObstructive sleep apnea Other conditions: Solid TumorView official trial listing → -
Completed NCT NCT02520063
Combination of Letrozole, Everolimus and TRC105 in Postmenopausal Women With Hormone-Receptor Positive and Her2 Negative Breast Cancer
Not yet reported, Not yet reported University of Alabama at Birmingham 15 participants Est. completion 2022-12-01 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02520180
Non-inferiority Study Comparing Firehawk Stent With Abbott Xience Family Stent (TARGET-AC)
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 1653 participants Est. completion 2022-06 1 siteCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT02524639
Sirolimus for the Treatment of Hyperinsulinism
Not yet reported, Not yet reported Children's Hospital of Philadelphia Est. completion 2018-05-29 1 site Stand-aloneOther conditions: HyperinsulinismView official trial listing → -
Withdrawn NCT NCT02528877
Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis
Not yet reported City of Hope Medical Center 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia in Remission, Primary Myelofibrosis, Primary Myelofibrosis, Prefibrotic Stage, Secondary Acute Myeloid Leukemia, Secondary MyelofibrosisView official trial listing → -
Completed NCT NCT02531932
Comparison of Single-Agent Carboplatin vs the Combination of Carboplatin and Everolimus for the Treatment of Advanced Triple-Negative Breast Cancer
Not yet reported Amy Tiersten 64 participants Est. completion 2024-10-19 3 sitesOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT02539459
Sporadic Angiomyolipomas (AMLs) Growth Kinetics While on Everolimus
Not yet reported Fox Chase Cancer Center 20 participants Est. completion 2018-08-20 8 sitesOther conditions: Sporadic Angiomyolipomas (AMLs)View official trial listing → -
Completed NCT NCT02539966
Safety & Performance Study of the FANTOM Sirolimus-Eluting Bioresorbable Coronary Scaffold
Not yet reported REVA Medical, Inc. 272 participants Est. completion 2024-09 28 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02542007
Safety and Efficacy of the Combo Bio-engineered Sirolimus-eluting Stent Versus the Nano Polymer-free Sirolimus-eluting Stent in the Treatment of Patients With de Novo Stenotic Lesions
Not yet reported OrbusNeich 440 participants Est. completion 2021-06-10 15 sites Stand-aloneOther conditions: Coronary ArteriosclerosisView official trial listing → -
Completed NCT NCT02545985
First-in-man Sirolimus-eluting Prolim® Stent Registry
Not yet reported Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland 204 participants Est. completion 2015-06Other conditions: Sirolimus-eluting Stainless Steel Coronary Stent Prolim®View official trial listing → -
Completed NCT NCT02551718
High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia
Not yet reported University of Washington 34 participants Est. completion 2021-05-13 1 siteOther conditions: Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Acute Leukemia of Ambiguous LineageView official trial listing → -
Completed NCT NCT02554955
A Study of Daclizumab (Zenapax) in Combination With Mycophenolate Mofetil (CellCept) and Sirolimus in Prevention of Acute Rejection in Heart Transplant Participants
Not yet reported Hoffmann-La Roche 36 participants Est. completion 2007-12 14 sites Stand-aloneOther conditions: Heart TransplantationView official trial listing → -
Terminated NCT NCT02560012
Personalized Targeted Inhibitors Treatment in Renal Cell Cancer
Not yet reported The University of Texas Health Science Center, Houston 4 participants Est. completion 2017-07-27 1 siteOther conditions: Carcinoma, Renal CellView official trial listing → -
Terminated NCT NCT02565901
Sirolimus, Docetaxel, and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer
Not yet reported, Not yet reported University of Washington 28 participants Est. completion 2020-06-16 1 site Stand-aloneOther conditions: Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IV Prostate Cancer AJCC v7, Metastatic Malignant Neoplasm in the BoneView official trial listing → -
Active, not recruiting NCT NCT02567435
Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma
Not yet reported National Cancer Institute (NCI) 325 participants Est. completion 2026-10-27 382 sitesObstructive sleep apneaView official trial listing → -
Withdrawn NCT NCT02569125
Open Label Study of Everolimus (RAD001) in Patients With Segmental Overgrowth Syndrome
Not yet reported Jochen Roessler Est. completion 2016-02 4 sitesOther conditions: Segmental Overgrowth SyndromeView official trial listing → -
Status unknown NCT NCT02577458
Study of the Combination of CM082 With Everolimus in Patients With mRCC
Not yet reported AnewPharma 18 participants Est. completion 2018-06 1 siteOther conditions: Renal Cell Carcinoma RecurrentView official trial listing → -
Completed NCT NCT02578069
First-in-man Trial Evaluating the Safety and Efficacy of the NOVA Intracranial Stent (NOVA Trial)
Not yet reported Sino Medical Sciences Technology Inc. 272 participants Est. completion 2020-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02579031
A Comparison of an Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent With a Durable Polymer Everolimus-Eluting Stent for Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
Not yet reported Insel Gruppe AG, University Hospital Bern 1300 participants Est. completion 2020-05 10 sitesCardiovascular disease Other conditions: Acute Coronary SyndromeView official trial listing → -
Enrolling by invitation NCT NCT02579044
Phase I/II Trial of Everolimus in Combination With Lonafarnib in Progeria
Not yet reported, Not yet reported Boston Children's Hospital 80 participants Est. completion 2027-03 1 siteOther conditions: ProgeriaView official trial listing → -
Status unknown NCT NCT02583542
A Study of AZD2014 in Combination With Selumetinib in Patients With Advanced Cancers
Not yet reported, Not yet reported Queen Mary University of London 118 participants Est. completion 2020-03 4 sitesOther conditions: Triple-Negative Breast Cancer, Squamous Cell Lung Cancer, Non-squamous Cell Lung Cancer With KRAS Mutations, Non-squamous Cell Lung Cancer With Wild-type KRASView official trial listing → -
Completed NCT NCT02583893
Biomarkers in Predicting Treatment Response to Sirolimus and Chemotherapy in Patients With High-Risk Acute Myeloid Leukemia
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 39 participants Est. completion 2023-05-17 1 site Stand-aloneOther conditions: Recurrent Adult Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Untreated Adult Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT02584647
PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors
Not yet reported, Not yet reported Gulam Manji 39 participants Est. completion 2024-10-01 5 sites Stand-aloneOther conditions: Sarcoma, Malignant Peripheral Nerve Sheath TumorsView official trial listing → -
Completed NCT NCT02587325
Phase 1/1b Study With Nab-sirolimus for Patients With Severe Pulmonary Arterial Hypertension
Not yet reported Aadi Bioscience, Inc. 15 participants Est. completion 2022-09-16 6 sites Stand-aloneOther conditions: Pulmonary HypertensionView official trial listing → -
Completed NCT NCT02588339
Panobinostat (LBH589): Acute Graft Versus Host Disease (aGVHD) Prevention
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 42 participants Est. completion 2021-07-13 1 site Stand-aloneOther conditions: Graft Versus Host Disease, GVHDView official trial listing → -
Completed NCT NCT02596828
Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma
Not yet reported University of Regensburg 4 participants Est. completion 2021-04 1 siteOther conditions: PineoblastomaView official trial listing → -
Withdrawn NCT NCT02597283
Coronary Bifurcation Lesions Treated With Biguard Stent System
Not yet reported Nanjing First Hospital, Nanjing Medical University Est. completion 2015-12 Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02599324
Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors
Not yet reported, Not yet reported Pharmacyclics LLC. 263 participants Est. completion 2021-08-20 65 sitesOther conditions: Metastatic Renal Cell Carcinoma, Advanced Urothelial Carcinoma, Advanced Gastric Adenocarcinoma, Metastatic Colorectal AdenocarcinomaView official trial listing → -
Completed NCT NCT02601157
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial
Not yet reported Seoul National University Hospital 2173 participants Est. completion 2022-08-14 12 sites Stand-aloneCardiovascular disease Other conditions: Stable Angina, Unstable AnginaView official trial listing → -
Status unknown NCT NCT02616848
Safety and Tolerability of Everolimus in Combination With Eribulin in Triple-negative Breast Cancers
Not yet reported Istituti Ospitalieri di Cremona 1 participants 1 siteOther conditions: Triple Negative Breast CancerView official trial listing → -
Withdrawn NCT NCT02619669
Neoadjuvant Run-In Study With TAK-228 Followed by Letrozole/TAK-228 in Women With High-Risk ER+/HER2- Breast Cancer
Not yet reported Gary Schwartz Est. completion 2019-06-14 1 siteOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT02623140
BIOFREEDOM Stent Versus ORSIRO Stent: SORT OUT IX
Not yet reported Odense University Hospital 3150 participants Est. completion 2023-10 1 siteOther conditions: Ischaemic Heart DiseaseView official trial listing → -
Active, not recruiting NCT NCT02629120
High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 45 participants Est. completion 2028-12-30 1 siteOther conditions: Chronic Granulomatous Disease TransplantView official trial listing → -
Completed NCT NCT02629575
Coroflex ISAR 2000 Registry
B. Braun Melsungen AG 2877 participants Est. completion 2017-12 3 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT02634931
Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex
Not yet reported Nobelpharma 94 participants Est. completion 2018-10 1 site Stand-aloneOther conditions: Tuberous Sclerosis, Angiofibroma, Hypomelanotic Macule, PlaqueView official trial listing → -
Completed NCT NCT02635789
Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)
Not yet reported Nobelpharma 62 participants Est. completion 2016-10 1 site Stand-aloneOther conditions: Tuberous Sclerosis, Angiofibroma, Hypomelanotic Macule, PlaqueView official trial listing → -
Status unknown NCT NCT02638428
Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy
Not yet reported Samsung Medical Center 90 participants Est. completion 2023-12 1 siteOther conditions: Relapsed Pediatric Solid Tumor, Refractory Pediatric Solid Tumor, Relapsed Pediatric AML, Refractory Pediatric AMLView official trial listing → -
Terminated NCT NCT02642094
Aging Mammary Stem Cells and Breast Cancer Prevention
Not yet reported LuZhe Sun 58 participants Est. completion 2022-05-01 1 siteOther conditions: Cancer of BreastView official trial listing → -
Completed NCT NCT02646319
Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations
Not yet reported Mayo Clinic 2 participants Est. completion 2018-04-24 2 sitesOther conditions: Advanced Malignant Neoplasm, Cervical Squamous Cell Carcinoma, Endometrial Carcinoma, Malignant Uterine Neoplasm, Recurrent Bladder Carcinoma, Recurrent Breast Carcinoma, Recurrent Cervical Carcinoma, Recurrent Head and Neck Carcinoma, Recurrent Malignant Neoplasm, Recurrent Ovarian Carcinoma, Recurrent Prostate Carcinoma, Recurrent Renal Cell Carcinoma, Solid Neoplasm, Stage III Bladder Cancer, Stage III Prostate Cancer, Stage III Renal Cell Cancer, Stage IIIA Breast Cancer, Stage IIIA Cervical Cancer, Stage IIIA Ovarian Cancer, Stage IIIB Breast Cancer, Stage IIIB Cervical Cancer, Stage IIIB Ovarian Cancer, Stage IIIC Breast Cancer, Stage IIIC Ovarian Cancer, Stage IV Breast Cancer, Stage IV Ovarian Cancer, Stage IV Prostate Cancer, Stage IV Renal Cell Cancer, Stage IVA Bladder Cancer, Stage IVA Cervical Cancer, Stage IVB Bladder Cancer, Stage IVB Cervical CancerView official trial listing → -
Completed NCT NCT02659254
A First-in-Man Study of the Firesorb BVS (FUTURE-I)
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 45 participants Est. completion 2021-03 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT02663323
Pilot Clinical Study of MeRes100 Sirolimus Eluting Bioresorbable Vascular Scaffold System
Not yet reported Meril Life Sciences Pvt. Ltd. 64 participants Est. completion 2020-07-05 4 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02669511
PQR309 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma
Not yet reported PIQUR Therapeutics AG 21 participants Est. completion 2018-01-12Other conditions: Primary Central Nervous System LymphomaView official trial listing → -
Status unknown NCT NCT02671318
Conversion to Sirolimus: Effects in Cytomegalovirus Infection Recurrence
Not yet reported Hospital do Rim e Hipertensão 250 participants Est. completion 2020-08 1 siteOther conditions: Cytomegalovirus InfectionsView official trial listing → -
Status unknown NCT NCT02675153
To Evaluate the Efficacy and Safety of Rapamycin for Crohn's Disease-related Stricture
Not yet reported The Second Hospital of Nanjing Medical University 15 participants Est. completion 2020-10 1 site Stand-aloneOther conditions: Crohn's DiseasesView official trial listing → -
Terminated NCT NCT02678143
Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease
Not yet reported Washington University School of Medicine 1 participants Est. completion 2021-11-16 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT02681016
Sirolimus-eluting Stent CALYPSO vs Everolimus-eluting Stent XIENCE
Not yet reported Meshalkin Research Institute of Pathology of Circulation 610 participants Est. completion 2017-07 1 site Stand-aloneCardiovascular disease Other conditions: Ischemic Heart Disease, Coronary Atherosclerosis, Coronary Artery StenosisView official trial listing → -
Completed NCT NCT02683291
Sirolimus Associated With Tacrolimus at Low Doses in Elderly Kidney Transplant Patients
Not yet reported Associação Médico Espírita de Botucatu 48 participants Est. completion 2016-01 Stand-aloneOther conditions: Disorder Related to Renal Transplantation, Cytomegalovirus InfectionsView official trial listing → -
Completed NCT NCT02684032
A Study To Assess The Tolerability And Clinical Activity Of Gedatolisib In Combination With Palbociclib/Letrozole Or Palbociclib/Fulvestrant In Women With Metastatic Breast Cancer
Not yet reported Celcuity Inc 141 participants Est. completion 2022-01-19 41 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02686619
Study Comparing Efficacy and Safety of Mycophenolate Mofetil (Cellcept) With Delayed Introduction of Sirolimus and Discontinuation of Cyclosporine, With Those of Mycophenolate Mofetil and Long Term Continuation of Cyclosporine in Renal Transplant Recipients
Not yet reported Hoffmann-La Roche 237 participants Est. completion 2011-01 17 sites Stand-aloneOther conditions: Renal TransplantationView official trial listing → -
Status unknown NCT NCT02687958
Study of Everolimus as Maintenance Therapy for Metastatic NEC With Pulmonary or Gastroenteropancreatic Origin
Not yet reported Gruppo Oncologico Italiano di Ricerca Clinica 30 participants Est. completion 2023-12 5 sitesOther conditions: Neuroendocrine CarcinomaView official trial listing → -
Completed NCT NCT02688829
The First-In-Man Pilot Study of Firehawk
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 21 participants Est. completion 2015-01Other conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT02688842
Evaluation of New Specifications (38mm) of FirehawkTM in the Treatment of Coronary Heart Disease
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 38 participants Est. completion 2021-01 1 siteOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT02688868
Evaluation of New Specifications (2.25mm) of FirehawkTM in the Treatment of Coronary Heart Disease ( Firehawk_2.25 )
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 38 participants Est. completion 2020-12 1 siteOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT02688881
Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid Tumors
Not yet reported Samsung Medical Center 6 participants Est. completion 2021-02-24 1 site Stand-aloneOther conditions: Refractory Solid TumorsView official trial listing → -
Completed NCT NCT02693158
The Direct III Post Market Study
Svelte Medical Systems, Inc. 440 participants Est. completion 2020-01 8 sitesCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT02694770
A Study Evaluating the Efficacy and Safety of Neihulizumab vs "Conventional Treatment" to Treat Sr-aGvHD
Not yet reported AbGenomics B.V Taiwan Branch Est. completion 2018-02 2 sitesOther conditions: Steroid-refractory aGvHD Subsequent to Allogeneic Hematopoietic Cell TransplantationView official trial listing → -
Status unknown NCT NCT02695459
Cisplatinum and Everolimus in Patients With Metastatic or Unresectable NEC of Extrapulmonary Origin
Not yet reported The Netherlands Cancer Institute 39 participants Est. completion 2021-08 3 sitesOther conditions: Neuroendocrine CarcinomasView official trial listing → -
Status unknown NCT NCT02698839
A Study to Evaluate the Efficacy and Safety of BuMA Supreme Drug Eluting Stent(DES)
Not yet reported Sino Medical Sciences Technology Inc. 539 participants Est. completion 2025-12 1 siteCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT02698852
A Study to Evaluate the Efficacy and Safety of BuMA Supreme Drug Eluting Stent(DES)
Not yet reported Sino Medical Sciences Technology Inc. 1000 participants Est. completion 2025-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT02711202
Sequential Targeting of Cluster of Differentiation 52 (CD52) and Tumor Necrosis Factor (TNF) Allows Early Minimization Therapy in Kidney Transplantation
Not yet reported Institute for Clinical and Experimental Medicine 20 participants Est. completion 2009-03Other conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT02711826
Treg Therapy in Subclinical Inflammation in Kidney Transplantation
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 32 participants Est. completion 2023-08-04 6 sitesOther conditions: Kidney Transplant, Adult Living Donor Kidney Transplant Recipients, Renal Transplant, Living Kidney DonorView official trial listing → -
Completed NCT NCT02722668
UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep
Not yet reported Masonic Cancer Center, University of Minnesota 15 participants Est. completion 2024-02-22 1 site Stand-aloneOther conditions: Acute Leukemia, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia/Lymphoma, Burkitt's Lymphoma, Natural Killer Cell Malignancies, Chronic Myelogenous Leukemia, Myelodysplastic Syndrome, Large-cell Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Relapsed Chronic Lymphocytic Leukemia, Relapsed Small Lymphocytic Lymphoma, Marginal Zone B-cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-cell Lymphoma, Prolymphocytic Leukemia, Bone Marrow Failure Syndromes, Myeloproliferative Neoplasms/Myelofibrosis, Biphenotypic/Undifferentiated/Prolymphocytic Leukemias, MRD Positive Leukemia, Leukemia or MDS in Aplasia, Relapsed T-Cell Lymphoma, Relapsed Multiple Myeloma, Plasma Cell LeukemiaView official trial listing → -
Completed NCT NCT02723877
PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)
Not yet reported, Not yet reported PIQUR Therapeutics AG 41 participants Est. completion 2018-10-03 5 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Withdrawn NCT NCT02723981
COMBO-Stent in Patients on Chronic Anticoagulant Therapy (COSTA) COSTA-Bleed and COSTA-Outcome Trials
Not yet reported IHF GmbH - Institut für Herzinfarktforschung Est. completion 2018-12 10 sites Stand-aloneOther conditions: Stable Angina, Unstable Angina, STEMI, NSTEMI, Coronary DiseaseView official trial listing → -
Completed NCT NCT02724020
MLN0128 and MLN0128 + MLN1117 Compared With Everolimus in the Treatment of Adults With Advanced or Metastatic Clear-Cell Renal Cell Carcinoma
Not yet reported Millennium Pharmaceuticals, Inc. 96 participants Est. completion 2020-10-13 36 sitesOther conditions: Clear-cell Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT02724332
Adjuvant Anti-Recurrence Treatment With Rapamycin on Early-stage HCC
Not yet reported Eastern Hepatobiliary Surgery Hospital 300 participants Est. completion 2015-12 1 siteOther conditions: Hepatocellular Carcinoma, RapamycinView official trial listing → -
Terminated NCT NCT02728700
Sirolimus and Mycophenolate Mofetil in Preventing GVHD in Patients With Hematologic Malignancies Undergoing HSCT
Not yet reported Stanford University 1 participants Est. completion 2018-07 1 site Stand-aloneOther conditions: Adult Hodgkin Lymphoma, Adult Myelodysplastic Syndrome, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Hodgkin Lymphoma, Childhood Myelodysplastic Syndrome, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Myelofibrosis, Primary Myelofibrosis, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Non-Hodgkin Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Non-Hodgkin Lymphoma, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Non-Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT02730923
Hormone Receptor Positive endometrIal Carcinoma Treated by Dual mTORC1/mTORC2 Inhibitor and Anastrozole (VICTORIA)
Not yet reported, Not yet reported Centre Leon Berard 72 participants Est. completion 2024-12 12 sitesOther conditions: Endometrial Carcinoma, Metastatic Carcinoma, Hormone Receptor Positive TumorView official trial listing → -
Completed NCT NCT02732119
Study of Ribociclib With Everolimus + Exemestane in HR+ HER2- Locally Advanced/Metastatic Breast Cancer Post Progression on CDK 4/6 Inhibitor.
Not yet reported, Not yet reported Novartis Pharmaceuticals 104 participants Est. completion 2020-02-25 25 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02732899
Sirolimus in Conjunction With Eylea vs Eylea Alone for Exudative AMD
Not yet reported Maturi, Raj K., M.D., P.C. 20 participants Est. completion 2017-04-04 1 site Stand-aloneOther conditions: Exudative Age Related Macular DegenerationView official trial listing → -
Completed NCT NCT02742051
A Trial of Neoadjuvant Everolimus Plus Letrozole Versus FEC in Women With ER-positive, HER2-negative Breast Cancer
Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 40 participants Est. completion 2020-03-14 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02753309
A Study of Rapamycin Combined With Intravesical BCG in Patients With Non-muscle Invasive Bladder Cancer
Not yet reported The University of Texas Health Science Center at San Antonio 33 participants Est. completion 2021-03-02 1 siteOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT02756572
Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms
Not yet reported University of Washington 30 participants Est. completion 2020-07-01 1 site Stand-aloneOther conditions: Blasts 10 Percent or More of Bone Marrow Nucleated Cells, Chronic Myelomonocytic Leukemia-2, High Grade Malignant Neoplasm, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts-2, Myeloid Neoplasm, Previously Treated Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02766465
Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)
Not yet reported Medical College of Wisconsin 138 participants Est. completion 2023-08-02 35 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Status unknown NCT NCT02768116
The Study of Active Transfer of Plaque Technique for Non-Left Main Coronary Bifurcation Lesions
Not yet reported Beijing Anzhen Hospital 316 participants Est. completion 2021-12 Stand-aloneOther conditions: Coronary Heart DiseaseView official trial listing → -
Status unknown NCT NCT02776202
HLA-Identical Sibling Donor Bone Marrow Transplantation for Individuals With Severe Sickle Cell Disease Using a Reduced Intensity Conditioning Regimen
Not yet reported National Guard Health Affairs 15 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT02776644
Clinical Outcome Of Advanced Renal Cell Carcinoma In Taiwan
Pfizer 1349 participants Est. completion 2017-12-30Other conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT02788201
Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma
Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2019-10-23 1 siteOther conditions: Urothelial Carcinoma, Bladder Cancer, Urinary Bladder NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT02790515
Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation
Not yet reported St. Jude Children's Research Hospital 170 participants Est. completion 2026-07-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Myeloid Sarcoma, Chronic Myeloid Leukemia (CML), Juvenile Myelomonocytic Leukemia (JMML), Myelodysplastic Syndrome (MDS), Non-Hodgkin Lymphoma (NHL)View official trial listing → -
Completed NCT NCT02793544
HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide
Not yet reported Center for International Blood and Marrow Transplant Research 80 participants Est. completion 2020-03 11 sitesOther conditions: Myelodysplastic Syndrome (MDS), Chronic Lymphocytic Leukemia (CLL), Chemotherapy-sensitive Lymphoma, Acute Lymphoblastic Leukemia (ALL)/T Lymphoblastic Lymphoma, Acute Myelogenous Leukemia (AML), Acute Biphenotypic Leukemia (ABL), Acute Undifferentiated Leukemia (AUL)View official trial listing → -
Completed NCT NCT02796898
Study of the Efficacy, Safety, and Pharmacokinetics of SM88 in Patients With Prostate Cancer
Not yet reported, Not yet reported Tyme, Inc 23 participants Est. completion 2019-05-30 5 sites Stand-aloneOther conditions: Prostate Cancer, Rising Prostate Specific Antigen (PSA)View official trial listing → -
Status unknown NCT NCT02802644
The Effect of DPP4 Inhibitor on Vasclular Healing
Not yet reported Chung-Ang University 66 participants 6 sitesType 2 diabetes Other conditions: Acute Coronary SyndromeView official trial listing → -
Completed NCT NCT02803892
Monotherapy With Rapamycin in Long-standing Type 1 Diabetes
Not yet reported Piemonti Lorenzo 55 participants Est. completion 2019-03 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02806947
A Study to Evaluate Steroid-free Treatment for Standard-Risk aGVHD (BMT CTN 1501)
Not yet reported Medical College of Wisconsin 127 participants Est. completion 2019-02-19 21 sites Stand-aloneOther conditions: Acute GVHDView official trial listing → -
Completed NCT NCT02809404
Dried Blood SPOT Analysis of Everolimus in Cancer Patients (SPOT-study)
Radboud University Medical Center 75 participants Est. completion 2017-01 1 siteOther conditions: Breast Cancer, Renal Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT02811861
Lenvatinib/Everolimus or Lenvatinib/Pembrolizumab Versus Sunitinib Alone as Treatment of Advanced Renal Cell Carcinoma
Not yet reported Eisai Inc. 1069 participants Est. completion 2027-03-31 183 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT02812940
Single-centre Study of Everolimus as GvHD Prophylaxis After Post-Transplantation Cyclophosphamide After Allogeneic SCT
Not yet reported University of Cologne 19 participants Est. completion 2020-12 1 siteOther conditions: Graft-versus-Host DiseaseView official trial listing → -
Status unknown NCT NCT02817802
BIOTRONIKS - Safety and Performance in de NOvo Lesion of NatiVE Coronary Arteries With Magmaris- Registry: BIOSOLVE-IV
Biotronik AG 2066 participants Est. completion 2025-10 2 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT02821026
Omental Islet Transplant
Not yet reported, Not yet reported University of Alberta 4 participants Est. completion 2019-11-13 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02821507
Sirolimus and Cyclophosphamide in Metastatic or Unresectable Myxoid Liposarcoma and Chondrosarcoma
Not yet reported Leiden University Medical Center 70 participants Est. completion 2021-12 7 sites Stand-aloneObstructive sleep apneaView official trial listing → -
Withdrawn NCT NCT02833506
Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Not yet reported Roswell Park Cancer Institute Est. completion 2019-08-15 1 site Stand-aloneOther conditions: Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma, Stage IIA Fallopian Tube Cancer, Stage IIA Ovarian Cancer, Stage IIB Fallopian Tube Cancer, Stage IIB Ovarian Cancer, Stage IIC Fallopian Tube Cancer, Stage IIC Ovarian Cancer, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Cancer, Stage IIIA Primary Peritoneal Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Cancer, Stage IIIB Primary Peritoneal Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Cancer, Stage IIIC Primary Peritoneal Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Cancer, Stage IV Primary Peritoneal CancerView official trial listing → -
Status unknown NCT NCT02836847
Molecularly Target Therapy With GEMOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma
Not yet reported Shanghai Jiao Tong University School of Medicine 152 participants Est. completion 2020-12 1 siteOther conditions: Cholangiocarcinoma of the Extrahepatic Bile Duct, Gallbladder CancerView official trial listing → -
Status unknown NCT NCT02837003
3-Month Discontinuation of Dual Antiplatelet Therapy After Ultimaster Sirolimus-Eluting Stent Implantation
Teikyo University 1500 participants Est. completion 2019-03 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT02842749
Phase IV Study of the Safety and Efficacy of Everolimus in Adult Patients With Progressive pNET in China
Not yet reported Novartis Pharmaceuticals 61 participants Est. completion 2024-02-22 5 sitesOther conditions: Pancreatic Neuroendocrine TumorsView official trial listing → -
Status unknown NCT NCT02844270
Galaxy Rapamycin Drug-Eluting Bioresorbable Coronary Stent System First-in-man Study
Not yet reported Shanghai Bio-heart Biological Technology Co., Ltd. 45 participants Est. completion 2021-12Other conditions: Heart DiseasesView official trial listing → -
Status unknown NCT NCT02853994
Safety and Efficacy of the DEVOIR Sirolimus-Coated Coronary Balloon in the Real-world Clinical Practice
MINVASYS 500 participants Est. completion 2018-09Other conditions: CADView official trial listing → -
Withdrawn NCT NCT02860494
Topical Everolimus in Patients With Tuberous Sclerosis Complex
Not yet reported, Not yet reported Hospices Civils de Lyon Est. completion 2024-12 1 siteOther conditions: Facial AngiofibromasView official trial listing → -
Completed NCT NCT02864706
SCHEDULE Follow Up Visit 5-7 yr
Not yet reported Novartis Pharmaceuticals 95 participants Est. completion 2017-09-25 6 sitesOther conditions: Heart TransplantationView official trial listing → -
Completed NCT NCT02867800
Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease
Not yet reported Monica Bhatia 24 participants Est. completion 2023-12-30 7 sites Stand-aloneOther conditions: Sickle Cell Disease, Graft Versus Host DiseaseView official trial listing → -
Status unknown NCT NCT02868203
OCT Based Edge and In-stent Vascular Response After Cordimax Stent in patIents With NSTE-ACS
Not yet reported Xijing Hospital 80 participants Est. completion 2020-08Cardiovascular disease Other conditions: Angina, UnstableView official trial listing → -
Completed NCT NCT02869087
The DESappear Study: Drug Eluting Scaffold
Not yet reported Elixir Medical Corporation 21 participants Est. completion 2021-04-30 11 sites Stand-aloneOther conditions: Peripheral Vascular DiseaseView official trial listing → -
Completed NCT NCT02870140
Thin Strut Sirolimus-eluting Stent in All Comers Population vs Everolimus-eluting Stent
Not yet reported ECRI bv 1435 participants Est. completion 2020-08-26 23 sites Stand-aloneOther conditions: Coronary StenosisView official trial listing → -
Completed NCT NCT02871791
Palbociclib With Everolimus + Exemestane In BC
Not yet reported, Not yet reported Dana-Farber Cancer Institute 41 participants Est. completion 2021-09 1 siteOther conditions: Human Epidermal Growth Factor 2 Negative Carcinoma of Breast, Hormone Receptor (HR)-Positive Breast CancerView official trial listing → -
Completed NCT NCT02874924
Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly
Not yet reported The University of Texas Health Science Center at San Antonio 34 participants Est. completion 2018-09 1 siteOther conditions: AgingView official trial listing → -
Completed NCT NCT02890069
A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat
Not yet reported Novartis Pharmaceuticals 298 participants Est. completion 2022-02-22 25 sitesOther conditions: Colorectal Cancer, Non-small Cell Lung Carcinoma (Adenocarcinoma), Triple Negative Breast Cancer, Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT02890160
A Trial of Firesorb in Patients With Coronary Artery Disease: FUTURE-II
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 430 participants Est. completion 2024-10-03 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02891603
A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression
Not yet reported, Not yet reported H. Lee Moffitt Cancer Center and Research Institute 40 participants Est. completion 2022-04-18 2 sites Stand-aloneOther conditions: Graft Vs Host Disease, GVHDView official trial listing → -
Status unknown NCT NCT02901353
A Prospective, Single-arm, Multi-centre, Observational, Real World Registry
Meril Life Sciences Pvt. Ltd. 400 participants Est. completion 2022-12-01 5 sitesOther conditions: Angina PectorisView official trial listing → -
Completed NCT NCT02905214
Coroflex ISAR 2000 Extended Registry (ISAR2000 Extended)
B. Braun Melsungen AG 4369 participants Est. completion 2021-12 3 sitesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT02908035
Temsirolimus Adventitial Delivery to Improve Angiographic Outcomes Below the Knee (TANGO)
Not yet reported Mercator MedSystems, Inc. 100 participants Est. completion 2021-09 8 sitesOther conditions: Chronic Limb IschemiaView official trial listing → -
Withdrawn NCT NCT02909335
De Novo Everolimus Versus Tacrolimus in Combination With Mofetil Mycophenolate and Low Dose Corticosteroids to Reduce Tacrolimus Induced Nephrotoxicity in Liver Transplantation: a Prospective, Multicentric, Randomised Study
Not yet reported Rennes University Hospital Est. completion 2021-11Other conditions: Liver TransplantationView official trial listing → -
Completed NCT NCT02913261
Safety and Efficacy of Ruxolitinib Versus Best Available Therapy in Patients With Corticosteroid-refractory Acute Graft vs. Host Disease After Allogeneic Stem Cell Transplantation
Not yet reported Novartis Pharmaceuticals 310 participants Est. completion 2021-04-23 103 sitesOther conditions: Corticosteroid Refractory Acute Graft vs Host DiseaseView official trial listing → -
Status unknown NCT NCT02915107
The SORT OUT IX STEMI OCT Trial
Not yet reported Odense University Hospital 80 participants Est. completion 2023-09 3 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT02915783
A Trial to Evaluate Efficacy and Safety of Lenvatinib in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Non Clear Cell Renal Cell Carcinoma (nccRCC) Who Have Not Received Any Chemotherapy for Advanced Disease
Not yet reported Eisai Inc. 41 participants Est. completion 2021-11-02 8 sitesOther conditions: Non Clear Cell Renal Cell Carcinoma (nccRCC)View official trial listing → -
Suspended NCT NCT02916485
Safety and Clinical Performance of a Sirolimus-eluting Absorbable Metal Scaffold
Not yet reported Biotronik AG 100 participants Est. completion 2018-09 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02917096
Ruxolitinib Phosphate and Chemotherapy Given Before and After Reduced Intensity Donor Stem Cell Transplant in Treating Patients With Myelofibrosis
Not yet reported City of Hope Medical Center 18 participants Est. completion 2023-08-31 1 site Stand-aloneOther conditions: Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Terminated NCT NCT02920450
Study of Paclitaxel, Carboplatin, and PF-05212384 in Advanced or Metastatic NSCLC (UF-STO-LUNG-002)
Not yet reported, Not yet reported University of Florida 3 participants Est. completion 2019-04-04 1 siteOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Status unknown NCT NCT02929030
Clinical Performance of Nano Plus Sirolimus-Eluting Stents in Patients With Coronary Artery Disease
Xijing Hospital 2500 participants Est. completion 2022-01 1 siteCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT02939365
Precision Medicine Offers Belatacept Monotherapy
Not yet reported University of California, San Francisco Est. completion 2022-12Other conditions: TransplantationView official trial listing → -
Completed NCT NCT02941224
First-in-human Evaluation of the SELUTION DCB, a Novel Sirolimus Coated Balloon in Peripheral Arteries
Not yet reported M.A. Med Alliance S.A. 50 participants Est. completion 2019-09 4 sites Stand-aloneOther conditions: Patients With Peripheral Artery Disease in the SFA or PAView official trial listing → -
Completed NCT NCT02954198
Once-daily Regimen With Envarsus® to Optimize Immunosuppression Management and Outcomes in Kidney Transplant Recipients
Not yet reported Medical University of South Carolina 40 participants Est. completion 2018-12-27 1 siteOther conditions: ImmunosuppressionView official trial listing → -
Completed NCT NCT02959918
Multi-Dose Safety/Pharmacodynamic Study of SEL-212/SEL-037 in Subjects With Symptomatic Gout & Elevated Blood Uric Acid
Not yet reported Selecta Biosciences, Inc. 152 participants Est. completion 2019-01 13 sitesOther conditions: Gout Chronic, HyperuricemiaView official trial listing → -
Completed NCT NCT02960997
Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study
Not yet reported Stanford University 8 participants Est. completion 2021-12-01 1 site Stand-aloneObstructive sleep apnea Other conditions: Weber-Cockayne SyndromeView official trial listing → -
Active, not recruiting NCT NCT02962414
Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment
Not yet reported Novartis Pharmaceuticals 206 participants Est. completion 2026-12-30 67 sitesOther conditions: Tuberous Sclerosis ComplexView official trial listing → -
Status unknown NCT NCT02968927
TB Host Directed Therapy
Not yet reported The Aurum Institute NPC 200 participants Est. completion 2020-12 1 siteOther conditions: TuberculosisView official trial listing → -
Completed NCT NCT02970630
Envarsus® Once Daily With Everolimus in Elderly Kidney Transplant Recipients: Pharmacokinetic and Clinical Study
Not yet reported Chiesi Farmaceutici S.p.A. 28 participants Est. completion 2018-02-22 6 sitesOther conditions: Kidney TransplantationView official trial listing → -
Status unknown NCT NCT02972671
Trial of MiStent Compared to Xience in Japan
Not yet reported Micell Technologies 120 participants Est. completion 2022-04-30 10 sites Stand-aloneOther conditions: Coronary (Artery); DiseaseView official trial listing → -
Completed NCT NCT02973204
Circulating Tumor Cells and Tumor DNA in HCC and NET
University of Aarhus 167 participants Est. completion 2020-01-08 1 siteOther conditions: Carcinoma, Hepatocellular, Neuroendocrine TumorsView official trial listing → -
Terminated NCT NCT02974686
Conversion From MPA to Zortress (Everolimus) for GI Toxicity Post-renal Transplantation
Not yet reported Washington University School of Medicine 1 participants Est. completion 2019-09 1 siteOther conditions: Kidney Transplant Rejection, Gastrointestinal Disorder, FunctionalView official trial listing → -
Completed NCT NCT02975882
Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors
Not yet reported Children's Oncology Group 33 participants Est. completion 2024-12-31 21 sites Stand-aloneOther conditions: Childhood Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Recurrent Primary Central Nervous System Neoplasm, Refractory Malignant Solid Neoplasm, Refractory Primary Central Nervous System NeoplasmView official trial listing → -
Completed NCT NCT02978456
Quantitative Coronary Angiography Versus Intravascular Ultrasound GUIDancE for Drug-Eluting Stent Implantation
Not yet reported CHEOL WHAN LEE, M.D., Ph.D 1528 participants Est. completion 2022-08-23 6 sites Stand-aloneOther conditions: Coronary Disease, Coronary StenosesView official trial listing → -
Active, not recruiting NCT NCT02979873
Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 84 participants Est. completion 2030-06-30 1 site Stand-aloneOther conditions: Severe Aplastic AnemiaView official trial listing → -
Completed NCT NCT02985125
LEE011 Plus Everolimus in Patients With Metastatic Pancreatic Adenocarcinoma Refractory to Chemotherapy
Not yet reported, Not yet reported Georgetown University 12 participants Est. completion 2020-09-28 1 siteOther conditions: Metastatic Pancreatic AdenocarcinomaView official trial listing → -
Terminated NCT NCT02987959
Study of TAK-228 (MLN0128) in Soft Tissue Sarcomas
Not yet reported Fox Chase Cancer Center 6 participants Est. completion 2020-07-24 1 siteOther conditions: Soft-tissue SarcomaView official trial listing → -
Withdrawn NCT NCT02990312
Impact of Sirolimus and Maraviroc on CCR5 Expression and the HIV-1 Reservoir in HIV-infected Kidney Transplant Recipients
Not yet reported University of Maryland, Baltimore Est. completion 2019-07-17 1 site Stand-aloneOther conditions: Hiv, Kidney Transplant, HIV Reservoir, CCR5View official trial listing → -
Completed NCT NCT02991807
RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome
Not yet reported, Not yet reported Boston Children's Hospital 46 participants Est. completion 2021-12-22 3 sitesOther conditions: PTEN Gene Mutation, PTEN Hamartoma Tumor SyndromeView official trial listing → -
Terminated NCT NCT02991898
Adoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme Malignancies
Not yet reported Masonic Cancer Center, University of Minnesota 3 participants Est. completion 2019-06-20 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Burkitt Lymphoma, Natural Killer Cell Malignancies, Chronic Myelogenous Leukemia, Myelodysplastic Syndromes, Large-cell Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone B-Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Leukemia, Hodgkin Lymphoma, Multiple Myeloma, Acute Myelogenous Leukemia, Biphenotypic Leukemia, Undifferentiated LeukemiaView official trial listing → -
Completed NCT NCT02995096
Tumor Characteristics, Pre-transplant Treatments and Immunosuppression After Liver Transplantation for Hepatocellular Carcinoma
Rigshospitalet, Denmark 23124 participants Est. completion 2019-03Other conditions: Liver TransplantationView official trial listing → -
Completed NCT NCT02996318
Treatment of Coronary In-Stent Restenosis by a Sirolimus (Rapamycin) Coated Balloon or a Paclitaxel Coated Balloon
Not yet reported InnoRa GmbH 50 participants Est. completion 2017-12-01 5 sites Stand-aloneOther conditions: DES In-stent StenosisView official trial listing → -
Status unknown NCT NCT03008083
Comparison Three vs Twelve Months of Dual Anti-Platelet Therapy After Stent Implantation
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 2446 participants Est. completion 2022-10 1 siteOther conditions: Drug-Eluting Stents, Percutaneous Coronary InterventionView official trial listing → -
Status unknown NCT NCT03008148
Phase II/III Trial of CCRT With or Without JP001 for Newly Diagnosed GBM
Not yet reported, Not yet reported Johnpro Biotech, Inc. 288 participants Est. completion 2025-04 2 sitesOther conditions: GlioblastomaView official trial listing → -
Active, not recruiting NCT NCT03008408
A Phase II, Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (Lee011) in Patients With Advanced or Recurrent Endometrial Carcinoma
Not yet reported M.D. Anderson Cancer Center 90 participants Est. completion 2028-08-31 2 sitesOther conditions: Recurrent Endometrial Carcinoma, Recurrent Endometrial Endometrioid Adenocarcinoma, Refractory Endometrial Carcinoma, Refractory Endometrial Endometrioid Adenocarcinoma, Stage III Uterine Corpus Cancer AJCC v8, Stage IIIA Uterine Corpus Cancer AJCC v8, Stage IIIB Uterine Corpus Cancer AJCC v8, Stage IIIC Uterine Corpus Cancer AJCC v8, Stage IIIC1 Uterine Corpus Cancer AJCC v8, Stage IIIC2 Uterine Corpus Cancer AJCC v8, Stage IV Uterine Corpus Cancer AJCC v8, Stage IVA Uterine Corpus Cancer AJCC v8, Stage IVB Uterine Corpus Cancer AJCC v8View official trial listing → -
Terminated NCT NCT03014297
Fosbretabulin With Everolimus in Neuroendocrine Tumors With Progression
Not yet reported Lowell Anthony, MD 17 participants Est. completion 2018-11-16 1 siteOther conditions: Neuroendocrine Tumors, EverolimusView official trial listing → -
Status unknown NCT NCT03016715
Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study
Not yet reported Premier Specialists, Australia 8 participants 1 site Stand-aloneObstructive sleep apnea Other conditions: Weber-Cockayne SyndromeView official trial listing → -
Completed NCT NCT03018223
Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 32 participants Est. completion 2021-03-18 1 site Stand-aloneOther conditions: Non-Hodgkin's Lymphoma, Acute Leukemia in Remission, Chronic Myeloid Leukemia, Primary Myelofibrosis, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Hodgkin Lymphoma, Multiple MyelomaView official trial listing → -
Completed NCT NCT03026465
Vessel Injury in Relation With Strut Thickness Assessed by OCT
Not yet reported Fundacion Investigacion Interhospitalaria Cardiovascular 50 participants Est. completion 2018-07-27 3 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT03027856
The BIFSORB Pilot Study II
Not yet reported Aarhus University Hospital Skejby 20 participants Est. completion 2024-12-31 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT03032406
CLEVER Pilot Trial: A Phase II Pilot Trial of HydroxyChLoroquine, EVErolimus or the Combination for Prevention of Recurrent Breast Cancer
Not yet reported Abramson Cancer Center at Penn Medicine 53 participants Est. completion 2027-01-01 1 siteOther conditions: Breast Cancer Stage IIBView official trial listing → -
Status unknown NCT NCT03040934
Firehawk™ Coronary Stent System in the Treatment of Coronary Chronic Total Occlusion Lesion(s)
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 196 participants Est. completion 2023-10 1 siteOther conditions: Drug-Eluting Stents, Percutaneous Coronary Intervention, Tomography, Optical CoherenceView official trial listing → -
Active, not recruiting NCT NCT03047213
Sapanisertib in Treating Patients With Locally Advanced or Metastatic Bladder Cancer With TSC1 and/or TSC2 Mutations
Not yet reported National Cancer Institute (NCI) 17 participants Est. completion 2026-11-12 20 sitesOther conditions: Locally Advanced Bladder Urothelial Carcinoma, Metastatic Transitional Cell Carcinoma, Metastatic Urothelial Carcinoma, Recurrent Bladder Carcinoma, Stage III Bladder Urothelial Carcinoma AJCC v6 and v7, Stage IV Bladder Urothelial Carcinoma AJCC v7View official trial listing → -
Completed NCT NCT03047980
Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome
Not yet reported, Not yet reported Anne Comi, MD 10 participants Est. completion 2020-10-27 2 sites Stand-aloneOther conditions: Sturge-Weber SyndromeView official trial listing → -
Active, not recruiting NCT NCT03049189
Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients
Not yet reported ITM Solucin GmbH 324 participants Est. completion 2029-11 52 sitesOther conditions: Neuroendocrine TumorsView official trial listing → -
Terminated NCT NCT03061708
Trial of Single Agent AZD2014 in RICTOR Amplified GC Patients as Second-line Therapy
Not yet reported Samsung Medical Center 1 participants Est. completion 2018-11-16 1 siteOther conditions: Stomach NeoplasmsView official trial listing → -
Suspended NCT NCT03065062
Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors
Not yet reported Dana-Farber Cancer Institute 75 participants Est. completion 2027-01-31 3 sitesOther conditions: Lung Cancer Squamous Cell, Solid Tumors, Head & Neck Cancer, Pancreatic CancerView official trial listing → -
Terminated NCT NCT03065387
Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation
Not yet reported M.D. Anderson Cancer Center 84 participants Est. completion 2026-04-23 1 siteOther conditions: Advanced Malignant Solid Neoplasm, EGFR Gene Amplification, EGFR Gene Mutation, ERBB2 Gene Amplification, ERBB2 Gene Mutation, ERBB3 Gene Mutation, ERBB4 Gene Mutation, KRAS Gene Mutation, Metastatic Malignant Solid Neoplasm, Refractory Malignant Solid NeoplasmView official trial listing → -
Completed NCT NCT03070301
A Study of LEE011 With Everolimus in Patients With Advanced Neuroendocrine Tumors
Not yet reported Memorial Sloan Kettering Cancer Center 21 participants Est. completion 2024-01-31 5 sitesOther conditions: Neuroendocrine TumorsView official trial listing → -
Completed NCT NCT03072485
Phase 1 Study of the Effects of Combining Topical FDA-approved Drugs on Age-related Pathways on the Skin of Healthy Volunteers
Not yet reported Anne Chang 10 participants Est. completion 2019-02-22 1 siteOther conditions: AgingView official trial listing → -
Active, not recruiting NCT NCT03077542
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease
Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 57 participants Est. completion 2026-08-31 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Terminated NCT NCT03082833
Phase II Trial of AZD2014 in TSC1/2 Mutated or TSC1/2 Null GC Patients as Second-line Chemotherapy
Not yet reported Samsung Medical Center 1 participants Est. completion 2018-11-16 1 siteOther conditions: Cancer of StomachView official trial listing → -
Completed NCT NCT03085823
The All-comers Sirolimus-coated Balloon European Registry
Fatebenefratelli and Ophthalmic Hospital 2123 participants Est. completion 2022-01 1 siteOther conditions: Percutaneous Coronary Intervention, Angioplasty, Balloon, Coronary, Coronary Angioplasty, Transluminal Balloon, Arteriosclerosis, CoronaryView official trial listing → -
Status unknown NCT NCT03089450
To Evaluate Safety and Efficacy of CGBIO Stent Compared to Biomatrix Flex Stent
Not yet reported CGBio Inc. 112 participants Est. completion 2018-06 1 site Stand-aloneCardiovascular disease Other conditions: Ischemic Heart Disease, Stable Angina, Unstable Angina, NSTEMI - Non-ST Segment Elevation MIView official trial listing → -
Completed NCT NCT03091465
Validation of the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) Prognostic Classification for Targeted Therapies (TKI/mTOR Inhibitors) in Second Line After First Line Treatment With Pazopanib
Spanish Oncology Genito-Urinary Group 530 participants Est. completion 2017-04-17 57 sitesOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Status unknown NCT NCT03095040
CM082 Combined With Everolimus in Chinese Patients With Metastatic Renal Cell Carcinoma
Not yet reported AnewPharma 390 participants Est. completion 2021-12 1 siteOther conditions: Renal Cell Cancer MetastaticView official trial listing → -
Completed NCT NCT03095703
Sirolimus and Familial Adenomatous Polyposis (FAP)
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 4 participants Est. completion 2018-12-10 1 site Stand-aloneOther conditions: Adenomatous Polyposis ColiView official trial listing → -
Completed NCT NCT03103893
Novel Compositions for Treating or Preventing Dermal Disorders
Not yet reported, Not yet reported Drexel University 36 participants Est. completion 2017-11-30 1 siteOther conditions: Dermal AtrophyView official trial listing → -
Completed NCT NCT03112603
A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)
Not yet reported Incyte Corporation 330 participants Est. completion 2022-12-15 191 sitesOther conditions: Graft-versus-host Disease (GVHD)View official trial listing → -
Active, not recruiting NCT NCT03114527
Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)
Not yet reported Fox Chase Cancer Center 48 participants Est. completion 2026-12 2 sitesOther conditions: Soft Tissue SarcomaView official trial listing → -
Withdrawn NCT NCT03120000
PQR309 in Phase 2 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma
Not yet reported PIQUR Therapeutics AG Est. completion 2019-12 4 sitesOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT03125772
Trial on Safety & Performance of TAXUS Element vs. XIENCE Prime Stent in Treatment of Coronary Lesion in Diabetics
Not yet reported Fortis Escorts Heart Institute 1830 participants Est. completion 2016-05 1 siteType 2 diabetes Other conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT03131999
LAM Pilot Study With Imatinib Mesylate
Not yet reported, Not yet reported Medical University of South Carolina 18 participants Est. completion 2019-03-07 2 sites Stand-aloneOther conditions: LymphangioleiomyomatosisView official trial listing → -
Suspended NCT NCT03139747
UPCC 36315 A Phase II Study Of Everolimus (RAD001) And Lenvatinib (E7080) In Patients With Metastatic Differentiated Thyroid Cancer Who Have Progressed on Lenvatinib Alone
Not yet reported Thomas Jefferson University 5 participants Est. completion 2022-05-30 1 siteOther conditions: Thyroid CancerView official trial listing → -
Completed NCT NCT03140449
Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous Sclerosis
Not yet reported National Taiwan University Hospital 52 participants Est. completion 2017-04-25Other conditions: Facial AngiofibromaView official trial listing → -
Active, not recruiting NCT NCT03150914
Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease Trial
Not yet reported University of Cincinnati 60 participants Est. completion 2025-06-30 8 sitesOther conditions: LAM, LymphangioleiomyomatosisView official trial listing → -
Completed NCT NCT03154281
Evaluation of the Safety and Tolerability of Niraparib With Everolimus in Advanced Gynecologic Malignancies and Breast
Not yet reported Avera McKennan Hospital & University Health Center 14 participants Est. completion 2023-05-01 1 siteOther conditions: Breast Cancer, Ovarian CancerView official trial listing → -
Active, not recruiting NCT NCT03155620
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
Not yet reported National Cancer Institute (NCI) 1377 participants Est. completion 2027-01-06 172 sitesObstructive sleep apnea Other conditions: Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Non-Hodgkin Lymphoma, Ann Arbor Stage IV Non-Hodgkin Lymphoma, Histiocytic Sarcoma, Juvenile Xanthogranuloma, Langerhans Cell Histiocytosis, Malignant Glioma, Recurrent Ependymoma, Recurrent Ewing Sarcoma, Recurrent Glioma, Recurrent Hepatoblastoma, Recurrent Langerhans Cell Histiocytosis, Recurrent Malignant Germ Cell Tumor, Recurrent Malignant Solid Neoplasm, Recurrent Medulloblastoma, Recurrent Neuroblastoma, Recurrent Non-Hodgkin Lymphoma, Recurrent Peripheral Primitive Neuroectodermal Tumor, Recurrent Primary Central Nervous System Neoplasm, Recurrent Rhabdoid Tumor, Recurrent Soft Tissue Sarcoma, Refractory Ewing Sarcoma, Refractory Glioma, Refractory Hepatoblastoma, Refractory Langerhans Cell Histiocytosis, Refractory Malignant Germ Cell Tumor, Refractory Malignant Solid Neoplasm, Refractory Medulloblastoma, Refractory Neuroblastoma, Refractory Non-Hodgkin Lymphoma, Refractory Peripheral Primitive Neuroectodermal Tumor, Refractory Primary Central Nervous System Neoplasm, Refractory Rhabdoid Tumor, Rhabdoid Tumor, Stage III Soft Tissue Sarcoma AJCC v7, Stage IV Soft Tissue Sarcoma AJCC v7, Wilms TumorView official trial listing → -
Completed NCT NCT03158389
NCT Neuro Master Match - N²M² (NOA-20)
Not yet reported, Not yet reported University Hospital Heidelberg 228 participants Est. completion 2023-02-22 13 sitesOther conditions: Glioblastoma, AdultView official trial listing → -
Completed NCT NCT03161340
Immunomodulatory Effects of Rapamycin on Pregnancy Rate of Patient With Recurrent Implantation Failure
Not yet reported Mehdi Yousefi 121 participants Est. completion 2018-06-20 2 sitesOther conditions: Recurrent Implantation FailureView official trial listing → -
Completed NCT NCT03163667
CB-839 With Everolimus vs. Placebo With Everolimus in Participants With Renal Cell Carcinoma (RCC)
Not yet reported Calithera Biosciences, Inc 69 participants Est. completion 2020-06-01 38 sitesOther conditions: Clear Cell Renal Cell CarcinomaView official trial listing → -
Withdrawn NCT NCT03166904
Phase II Trial of AZD2014 in RICTOR Amplified Solid Cancer Patients Refractory to Standard Chemotherapy
Not yet reported Samsung Medical Center Est. completion 2018-07-31 1 siteOther conditions: Solid TumorView official trial listing → -
Completed NCT NCT03173560
Trial to Assess Safety and Efficacy of Lenvatinib (18 mg vs. 14 mg) in Combination With Everolimus in Participants With Renal Cell Carcinoma
Not yet reported Eisai Inc. 343 participants Est. completion 2024-06-20 93 sitesOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT03174171
Open-label Study on Treatment of Primary Aldosteronism With Everolimus
Not yet reported University Hospital, Basel, Switzerland 12 participants Est. completion 2018-06-25 1 siteOther conditions: Primary AldosteronismView official trial listing → -
Completed NCT NCT03176238
Study in Post-menopausal Women With Hormone Receptor Positive, HER2-negative Advanced Breast Cancer
Not yet reported Novartis Pharmaceuticals 235 participants Est. completion 2019-01-29 55 sitesOther conditions: Post Menopausal Breast CancerView official trial listing → -
Status unknown NCT NCT03185221
Cordimax China Post Market Surveillance
Not yet reported Shandong Branden Med.Device Co.,Ltd 3660 participants Est. completion 2020-06-20 1 siteOther conditions: Coronary Artery StenosisView official trial listing → -
Completed NCT NCT03188068
Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma
Not yet reported West China Hospital 30 participants Est. completion 2021-12-31 1 siteOther conditions: Kaposiform Hemangioendothelioma, Kasabach Merritt PhenomenonView official trial listing → -
Completed NCT NCT03190174
Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers
Not yet reported, Not yet reported Sarcoma Oncology Research Center, LLC 34 participants Est. completion 2021-12-02 1 siteOther conditions: Ewing Sarcoma, PEComa, Epithelioid Sarcoma, Desmoid Tumor, Chordoma, Non Small Cell Lung Cancer, Urothelial Carcinoma, Melanoma, Renal Cell Carcinoma, Squamous Cell Carcinoma, Hepatocellular Carcinoma, Classical Hodgkin Lymphoma, Colorectal Cancer, MTOR Activating MutationView official trial listing → -
Terminated NCT NCT03190473
OPTIMIZE IDE for the Treatment of ACS
Not yet reported Svelte Medical Systems, Inc. 1630 participants Est. completion 2023-03-08 72 sitesOther conditions: Acute Coronary SyndromeView official trial listing → -
Active, not recruiting NCT NCT03192397
Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant
Not yet reported, Not yet reported Roswell Park Cancer Institute 35 participants Est. completion 2027-05-21 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia in Remission, Adult Acute Lymphoblastic Leukemia in Complete Remission, Chronic Myelogenous Leukemia, BCR-ABL1 Positive in Remission, Chronic Myelomonocytic Leukemia in Remission, Graft Versus Host Disease, Hodgkin Lymphoma, Minimal Residual Disease, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Non-Hodgkin Lymphoma, Plasma Cell Myeloma, Severe Aplastic Anemia, Waldenstrom MacroglobulinemiaView official trial listing → -
Completed NCT NCT03198949
A Study Investigating the Anti-epileptic Efficacy of Afinitor (Everolimus) in Patients With Refractory Seizures Who Have Focal Cortical Dysplasia Type II (FCD II)
Not yet reported Yonsei University 23 participants Est. completion 2020-09-11 1 siteOther conditions: Epilepsy and Focal Cortical Dysplasia IIView official trial listing → -
Status unknown NCT NCT03199014
the Effect of Prolonged Inflation Time During Stents Deployment for ST-elevation Myocardial Infarction
Not yet reported West China Hospital 60 participants Est. completion 2017-07 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT03203525
Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer
Not yet reported M.D. Anderson Cancer Center 38 participants Est. completion 2026-07-22 1 siteOther conditions: Advanced Malignant Neoplasm, Colorectal Carcinoma Metastatic in the Liver, Metastatic Malignant Neoplasm in the Liver, Refractory Malignant NeoplasmView official trial listing → -
Terminated NCT NCT03205046
A Study of Acalabrutinib and Vistusertib in Subjects With Relapsed/Refractory B-cell Malignancies
Not yet reported, Not yet reported Acerta Pharma BV 25 participants Est. completion 2019-11-20 11 sitesOther conditions: DLBCL, Richter SyndromeView official trial listing → -
Active, not recruiting NCT NCT03216733
SORT OUT X - Combo Stent Versus ORSIRO Stent
Not yet reported Aarhus University Hospital Skejby 3148 participants Est. completion 2028-12-31 4 sitesCardiovascular disease Other conditions: Coronary Heart Disease, Angina PectorisView official trial listing → -
Completed NCT NCT03216967
Multicenter Randomized Two-arms Study Evaluating the BK Viral Clearance in Kidney Transplant Recipients With BK Viremia.
Not yet reported University Hospital, Strasbourg, France 130 participants Est. completion 2024-08-01 15 sitesOther conditions: BK Virus Nephropathy After Kidney TransplantationView official trial listing → -
Status unknown NCT NCT03217669
Epacadostat (INCB24360) in Combination With Sirolimus in Advanced Malignancy
Not yet reported Chao Huang 15 participants Est. completion 2025-08-01 2 sites Stand-aloneOther conditions: Advanced Solid Tumor, Non-small Cell Lung Cancer (NSCLC)View official trial listing → -
Status unknown NCT NCT03225417
Ixazomib in the Prophylaxis of Chronic Graft-versus-host Disease.
Not yet reported, Not yet reported Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 142 participants Est. completion 2024-12-31 8 sites Stand-aloneOther conditions: Hematopoietic Stem Cell Transplantation, Multiple MyelomaView official trial listing → -
Completed NCT NCT03234348
MAGnesium-based Bioresorbable Scaffold in ST Segment Elevation Myocardial Infarction
Not yet reported Hospital Clinic of Barcelona 151 participants Est. completion 2019-10-31 11 sites Stand-aloneCardiovascular disease Other conditions: Acute Coronary Syndrome, StentView official trial listing → -
Status unknown NCT NCT03239015
Efficacy and Safety of Precision Therapy in Refractory Tumor
Not yet reported Baodong Qin 300 participants Est. completion 2023-12-31 1 siteOther conditions: Rare Tumor, Refractory TumorView official trial listing → -
Completed NCT NCT03240731
HLA Haploidentical Bone Marrow Transplant in Patients With Severe Sickle Cell Disease
Not yet reported Centre Hospitalier Intercommunal Creteil 25 participants Est. completion 2024-04-08 7 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT03242096
Treatment of Coronary In-stent Restenosis (ISR) by a Sirolimus Coated or a Paclitaxel Coated Balloon
Not yet reported InnoRa GmbH 50 participants Est. completion 2021-01-31 5 sites Stand-aloneOther conditions: Coronary RestenosisView official trial listing → -
Completed NCT NCT03245151
Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors
Not yet reported, Not yet reported Eisai Inc. 64 participants Est. completion 2022-09-30 50 sitesOther conditions: Recurrent and Refractory Solid TumorsView official trial listing → -
Terminated NCT NCT03246906
Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation
Not yet reported Fred Hutchinson Cancer Center 150 participants Est. completion 2025-05-03 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Aggressive Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma, Mantle Cell Lymphoma, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Hodgkin Lymphoma, Recurrent Plasma Cell Myeloma, Recurrent Small Lymphocytic Lymphoma, Recurrent Waldenstrom Macroglobulinemia, Hematologic and Lymphocytic Disorder, Blastic Plasmacytoid Dendritic Cell NeoplasmView official trial listing → -
Completed NCT NCT03253913
Resveratrol and Sirolimus in Lymphangioleiomyomatosis Trial
Not yet reported University of Cincinnati 25 participants Est. completion 2022-10-15 1 site Stand-aloneOther conditions: LymphangioleiomyomatosisView official trial listing → -
Completed NCT NCT03256864
Twice-daily Tacrolimus and Everolimus Convert to Once-daily Tacrolimus and Everolimus in Liver Transplant Recipient
Not yet reported Chang Gung Memorial Hospital 10 participants Est. completion 2020-05-30 1 siteOther conditions: Liver TransplantationView official trial listing → -
Completed NCT NCT03263260
Post-marketing Registry of Inspiron Sirolimus Eluting Coronary Stent
Scitech Produtos Medicos SA 2504 participants Est. completion 2024-01-21 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT03263559
Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)
Not yet reported Medical College of Wisconsin 95 participants Est. completion 2025-01-29 32 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Status unknown NCT NCT03284255
Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System Clinical Study
Not yet reported Shanghai Bio-heart Biological Technology Co., Ltd. 431 participants Est. completion 2024-08-30 25 sitesCardiovascular disease Other conditions: Antineoplastic AgentsView official trial listing → -
Terminated NCT NCT03284957
Phase 1/2 Study of Amcenestrant (SAR439859) Single Agent and in Combination With Other Anti-cancer Therapies in Postmenopausal Women With Estrogen Receptor Positive Advanced Breast Cancer
Not yet reported, Not yet reported Sanofi 136 participants Est. completion 2024-11-08 25 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT03285802
Treatment Plan for an Individual Patient With Recurrent Uterine Papillary Serous Carcinoma (UPSC) With PIK3CA Gene Mutation
Not yet reported, Not yet reported Greater Baltimore Medical Center 1 participants Est. completion 2019-02-12 1 siteOther conditions: Uterine CancerView official trial listing → -
Status unknown NCT NCT03287167
Comparison One vs Six Months of Dual Antiplatelet Therapy After Implanted Firehawk TM Stent in High Bleeding Risk Patients With Coronary Artery Disease
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 1720 participants Est. completion 2023-07-30 1 siteOther conditions: Coronary Disease, Drug Eluting Stent, Percutaneous Coronary Intervention, Dual Antiplatelet TherapyView official trial listing → -
Enrolling by invitation NCT NCT03292861
The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant Recipients
Not yet reported Cedars-Sinai Medical Center 60 participants Est. completion 2026-03-31 2 sitesOther conditions: Heart TransplantationView official trial listing → -
Withdrawn NCT NCT03298958
Secondary Prevention Trial of Rapamycin in Patients With Resected Non-muscle Invasive Bladder Cancer
Not yet reported The University of Texas Health Science Center at San Antonio Est. completion 2022-05-01 1 siteOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT03304678
Discovery of Sirolimus Sensitive Biomarkers in Blood
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 33 participants Est. completion 2025-03-14 1 siteOther conditions: LymphangioleiomyomatosisView official trial listing → -
Completed NCT NCT03312738
A Study of Everolimus Plus Exemestane in Chinese Postmenopausal Women With Estrogen Receptor Positive, Locally Advanced, Recurrent, or Metastatic Breast Cancer After Recurrence or Progression on Non-steroidal Aromatase Inhibitor
Not yet reported Novartis Pharmaceuticals 159 participants Est. completion 2022-04-25 15 sitesOther conditions: Advanced Breast CancerView official trial listing → -
Completed NCT NCT03324373
Lenvatinib and Everolimus in Renal Cell Carcinoma (RCC)
Not yet reported Yousef Zakharia 11 participants Est. completion 2024-08-28 1 siteOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT03328104
Everolimus in Combination With Nelarabine, Cyclophosphamide and Etoposide in Lymphoblastic Leukemia/Lymphoma
Not yet reported Emory University 8 participants Est. completion 2023-06-29 4 sitesOther conditions: Lymphoblastic Leukemia, Lymphoblastic LymphomaView official trial listing → -
Terminated NCT NCT03333694
Safety, Tolerability, and Efficacy Study of CLL442 in Patients With Cutaneous Squamous Cell Carcinoma in Situ (SCCis)
Not yet reported Novartis Pharmaceuticals 40 participants Est. completion 2018-11-01 8 sitesOther conditions: Cutaneous Squamous Cell Carcinoma in Situ (CSCCis)View official trial listing → -
Active, not recruiting NCT NCT03334617
Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy
Not yet reported AstraZeneca 528 participants Est. completion 2026-09-11 45 sitesOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT03352427
Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations
Not yet reported University of Michigan Rogel Cancer Center 3 participants Est. completion 2019-05-15 1 siteOther conditions: Glioma, High Grade Glioma, Pontine TumorsView official trial listing → -
Completed NCT NCT03355794
A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)
Not yet reported Children's Hospital Medical Center, Cincinnati 19 participants Est. completion 2022-07-31 7 sitesOther conditions: Diffuse Intrinsic Pontine Glioma, Malignant Glioma of Brain, High Grade Glioma, Bithalamic High Grade Glioma, Brainstem Glioma, Glioblastoma, Anaplastic AstrocytomaView official trial listing → -
Completed NCT NCT03359538
Rapamycin Treatment for ALS
Not yet reported Azienda Ospedaliero-Universitaria di Modena 63 participants Est. completion 2022-02-15 7 sitesOther conditions: Amyotrophic Lateral SclerosisView official trial listing → -
Terminated NCT NCT03363763
Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex
Not yet reported Aucta Pharmaceuticals, Inc 24 participants Est. completion 2023-03-24 8 sitesOther conditions: Angiofibroma of Face, Tuberous SclerosisView official trial listing → -
Completed NCT NCT03364764
Sirolimus Treatment for Refractory PRCA
Not yet reported Bing Han 64 participants Est. completion 2021-05-01 1 site Stand-aloneOther conditions: Pure Red Cell AplasiaView official trial listing → -
Status unknown NCT NCT03365869
A Pilot-Study of Sirolimus for the Treatment of Systemic Sclerosis
Not yet reported Peking University People's Hospital 72 participants Est. completion 2019-06-30Other conditions: Systemic SclerosisView official trial listing → -
Completed NCT NCT03383380
Rapamycin Treatment for Activated Phosphoinositide 3-Kinase δ Syndrome
Not yet reported, Not yet reported Children's Hospital of Fudan University 30 participants Est. completion 2023-11-30 2 sitesOther conditions: Activated PI3K-delta Syndrome, Immunodeficiency PrimaryView official trial listing → -
Completed NCT NCT03386539
Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score
Not yet reported Boston Children's Hospital 211 participants Est. completion 2023-05-17 25 sitesChronic kidney disease Other conditions: Pediatric Heart Transplantation, Immunosuppression, Cardiac Allograft Vasculopathy, Heart Transplant Failure and Rejection, Post-transplant Lymphoproliferative Disorder, Heart Transplant InfectionView official trial listing → -
Completed NCT NCT03387020
Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors
Not yet reported Pediatric Brain Tumor Consortium 22 participants Est. completion 2020-04-01 12 sitesOther conditions: CNS Embryonal Tumor, Not Otherwise Specified, Malignant Glioma, Recurrent Atypical Teratoid/Rhabdoid Tumor, Recurrent Childhood Ependymoma, Recurrent Diffuse Intrinsic Pontine Glioma, Recurrent Medulloblastoma, Refractory Diffuse Intrinsic Pontine GliomaView official trial listing → -
Completed NCT NCT03399994
Clinical Trial of Abluminus DES+ Sirolimus Eluting Stent Versus Everolimus-eluting DES
Not yet reported Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS 137 participants Est. completion 2022-07-26 6 sitesCardiovascular disease Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03413722
Alterations in Cognitive Function and Cerebral Blood Flow After Conversion From Calcineurin Inhibitors (CNIs) to Everolimus
University of Kansas Medical Center 30 participants Est. completion 2022-10-01 1 siteOther conditions: End Stage Renal DiseaseView official trial listing → -
Completed NCT NCT03415750
Everolimus and Tacrolimus Combination for Regression of Left Ventricular Hypertrophy in Renal Transplants
Not yet reported Edoardo Melilli 20 participants Est. completion 2020-05 1 siteOther conditions: Hypertrophy, Left VentricularView official trial listing → -
Terminated NCT NCT03421756
Stem Cell Transplant in Patients With Severe Sickle Cell Disease
Not yet reported Kathleen Dorritie 1 participants Est. completion 2022-05-15 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT03433183
SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors
Not yet reported Sarcoma Alliance for Research through Collaboration 21 participants Est. completion 2023-10-01 5 sites Stand-aloneOther conditions: Malignant Peripheral Nerve Sheath Tumors, Neurofibromatosis 1View official trial listing → -
Completed NCT NCT03434704
Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazole
Not yet reported Ciceri Fabio 10 participants Est. completion 2019-10-13 1 site Stand-aloneOther conditions: Transplant-Related Hematologic Malignancy, Leukemia, Acute, Myelodysplastic Syndromes, Graft Vs Host Disease, Fungal InfectionView official trial listing → -
Terminated NCT NCT03436732
Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesothelioma
Not yet reported National Cancer Institute (NCI) 5 participants Est. completion 2019-04-30 1 siteOther conditions: MesotheliomaView official trial listing → -
Completed NCT NCT03439462
Nab-Sirolimus in Combination With FOLFOX & BEV as 1st Line Therapy in Patients With Advanced or Metastatic Colorectal Cancer
Not yet reported, Not yet reported Aadi Bioscience, Inc. 60 participants Est. completion 2022-08-26 6 sites Stand-aloneOther conditions: Colorectal Cancer MetastaticView official trial listing → -
Status unknown NCT NCT03454724
Study of MeRes100 in the Treatment of Patient With Coronary Artery Disease.
Not yet reported Meril Life Sciences Pvt. Ltd. 484 participants Est. completion 2024-12-01 Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT03456700
Auranofin and Sirolimus in Treating Participants With Ovarian Cancer
Not yet reported Mayo Clinic 22 participants Est. completion 2019-07-31 1 site Stand-aloneOther conditions: Ovarian Serous Tumor, Recurrent Ovarian CarcinomaView official trial listing → -
Completed NCT NCT03463265
Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed Glioblastoma
Not yet reported Aadi Bioscience, Inc. 62 participants Est. completion 2022-08-26 3 sites Stand-aloneOther conditions: High Grade Recurrent Glioma and Newly Diagnosed GlioblastomaView official trial listing → -
Completed NCT NCT03468478
Comparison of the Efficacy and Safety of Sirolimus Versus Everolimus Versus Mycophenolate in Kidney Transplantation
Not yet reported Hospital do Rim e Hipertensão 1209 participants Est. completion 2021-08-23 1 site Stand-aloneOther conditions: Kidney Transplant InfectionView official trial listing → -
Completed NCT NCT03471234
Latin America Real World Study With Inspiron Drug Eluting Stent - INSPIRON LATITUDE
Scitech Produtos Medicos SA 299 participants Est. completion 2022-08-02 2 sitesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT03475563
BiOSS Study (BiOSS LIM C Stent Registry in Bifurcated Lesions)
Hospital Universitari Vall d'Hebron Research Institute 100 participants Est. completion 2019-12-30 3 sitesCardiovascular diseaseView official trial listing → -
Terminated NCT NCT03484234
Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-VII: Sirolimus-eluting (Ultimaster) vs. Everolimus-Eluting Stents (Xience)
Not yet reported Seung-Jung Park 36 participants Est. completion 2019-09-06 2 sitesCardiovascular disease Other conditions: Coronary StenosisView official trial listing → -
Status unknown NCT NCT03486366
Application of Novel Diagnostic and Therapeutical Methods in Epilepsy and Neurodevelopmental Abnormalities in Children.
Not yet reported Medical University of Warsaw 120 participants Est. completion 2020-03-30 1 siteOther conditions: EpilepsyView official trial listing → -
No Longer Available NCT NCT03493152
Expanded Access to Everolimus, for an Individual Patient With GIST (Gastrointestinal Stromal Tumors)(CTMS#18-0019)
The University of Texas Health Science Center at San AntonioOther conditions: Gastrointestinal Stromal TumorView official trial listing → -
No Longer Available NCT NCT03493165
Expanded Access to Everolimus, for an Individual Patient With Uterine Sarcoma (CTMS#18-0020)
The University of Texas Health Science Center at San AntonioOther conditions: Uterine SarcomaView official trial listing → -
Status unknown NCT NCT03500367
Efficacy and Safety of Rapamycin (Sirolimus) in the Treatment of Symptomatic Uterine Fibroids and Leiomyomatosis
Not yet reported Peking Union Medical College Hospital 25 participants Est. completion 2022-12-31 1 siteOther conditions: Uterine FibroidsView official trial listing → -
Status unknown NCT NCT03500848
Sirolimus-based Immunosuppression Treatment Regimen for Liver Transplantation
Not yet reported, Not yet reported Southern Medical University, China 130 participants Est. completion 2023-05-31 3 sites Stand-aloneOther conditions: Liver TransplantationView official trial listing → -
Completed NCT NCT03502902
The Safety, Tolerability and Pharmacokinetic Study of HEC68498 in Healthy Male and Female Subjects
Not yet reported Sunshine Lake Pharma Co., Ltd. 55 participants Est. completion 2019-03-15 1 siteOther conditions: Idiopathic Pulmonary FibrosisView official trial listing → -
Completed NCT NCT03504241
Tolerance by Engaging Antigen During Cellular Homeostasis
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 8 participants Est. completion 2025-09-16 1 site Stand-aloneOther conditions: Kidney Transplantation, Renal Transplantation, Renal Transplant RecipientView official trial listing → -
Completed NCT NCT03507205
Korean Nationwide Multicenter Pooled Registry of Drug-Eluting Stents
Seoul National University Hospital 17286 participants Est. completion 2017-11-30 37 sitesCardiovascular diseaseView official trial listing → -
Terminated NCT NCT03508219
POLish Bifurcation Optimal Treatment Strategy Study for Left Main Bifurcation Percutaneous Coronary Intervention (PCI)
Not yet reported ECRI bv 130 participants Est. completion 2021-04-15 15 sites Stand-aloneOther conditions: Coronary StenosisView official trial listing → -
Completed NCT NCT03509142
A First-in-Man Study of IBS
Not yet reported Lifetech Scientific (Shenzhen) Co., Ltd. 45 participants Est. completion 2023-12-10 1 site Stand-aloneOther conditions: Single Coronary Vessel DiseaseView official trial listing → -
Status unknown NCT NCT03509532
DRUG ELUTING STENT FOR DIABETIC PATIENTS IN CORONARY ARTERY DISEASE TREATMENT
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio 5000 participants Est. completion 2022-01 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT03510676
The ILLUMINA Study. (ILLUMINA)
Not yet reported CID - Carbostent & Implantable Devices 100 participants Est. completion 2019-03-07 10 sitesOther conditions: Peripheral Arterial DiseaseView official trial listing → -
Terminated NCT NCT03512756
A Randomized Phase 2/3 Multi-Center Study of SM-88 in Participants With Metastatic Pancreatic Cancer
Not yet reported, Not yet reported Tyme, Inc 130 participants Est. completion 2021-12-28 20 sites Stand-aloneOther conditions: Pancreatic CancerView official trial listing → -
Completed NCT NCT03522298
Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma
Not yet reported Kazia Therapeutics Limited 30 participants Est. completion 2023-03-30 6 sitesOther conditions: Glioblastoma, AdultView official trial listing → -
Completed NCT NCT03525834
Safety and Efficacy of Everolimus (Afinitor®) in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex.
Not yet reported Novartis Pharmaceuticals 40 participants Est. completion 2020-09-25 5 sitesOther conditions: Renal AngiomyolipomaView official trial listing → -
Withdrawn NCT NCT03531281
Human Lysozyme Goat Milk in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant
Not yet reported City of Hope Medical Center Est. completion 2022-12-30 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell Neoplasm, Hematopoietic Cell Transplantation RecipientView official trial listing → -
Status unknown NCT NCT03548272
BiOSS LIM C vs 2nd Generation DES in Non-LM Bifurcations
Not yet reported Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland 518 participants Est. completion 2020-06 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT03563989
STENTYS Xposition S in the Treatment of Chronic Total Artery Occlusion
Not yet reported Assistance Publique - Hôpitaux de Paris 50 participants Est. completion 2019-12 1 site Stand-aloneCardiovascular disease Other conditions: Chronic Total OcclusionView official trial listing → -
Status unknown NCT NCT03571438
Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Human Renal Tumors
Not yet reported University Hospital, Grenoble 100 participants Est. completion 2024-09-30 1 siteOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT03577431
Liver Transplantation With Tregs at MGH
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 9 participants Est. completion 2026-02-05 1 siteOther conditions: Liver TransplantView official trial listing → -
Terminated NCT NCT03578432
Everolimus in Restoring Salivary Gland Function in Participants With Locally Advanced Head and Neck Cancer Treated With Radiation Therapy
Not yet reported University of Arizona 2 participants Est. completion 2019-11-15 1 siteOther conditions: Salivary Gland Dysfunction, Xerostomia, Head and Neck CancerView official trial listing → -
Status unknown NCT NCT03580239
Everolimus in Castrated Resistant Prostate Cancer(CRPC)Patients With PI3K-AKT-mTOR Signaling Pathway Deficiency
Not yet reported Tianjin Medical University Second Hospital 120 participants Est. completion 2023-12-01 4 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT03582878
Sirolimus vs Mycophenolate With Tacrolimus in Simultaneous Pancreas and Kidney Transplantation
Not yet reported Institute for Clinical and Experimental Medicine 238 participants Est. completion 2019-01-01 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03583307
Efficacy and Safety of Sirolimus to Vascular Anomalies
Not yet reported West China Hospital 126 participants Est. completion 2021-02-19 1 site Stand-aloneOther conditions: Vascular AnomalyView official trial listing → -
Status unknown NCT NCT03587922
FANTOM Post Market Clinical Trial
Not yet reported REVA Medical, Inc. 1500 participants Est. completion 2025-05-01 10 sitesCardiovascular diseaseView official trial listing → -
Terminated NCT NCT03589976
A Futility Trial of Sirolimus in Multiple System Atrophy
Not yet reported NYU Langone Health 47 participants Est. completion 2021-01-01 1 site Stand-aloneOther conditions: Multiple System AtrophyView official trial listing → -
Withdrawn NCT NCT03596970
Study of the Effect of Everolimus Immunosuppressive Combination Therapies on Renal Function When Used as a Maintenance Treatment for Liver Transplant Patients.
Not yet reported Novartis Pharmaceuticals Est. completion 2020-12Other conditions: Liver TransplantationView official trial listing → -
Terminated NCT NCT03600948
BIOFLOW-SV All Comers Registry
Biotronik AG 261 participants Est. completion 2021-10-06 2 sitesOther conditions: de Novo, Symptomatic Ischemic Heart Disease, Restenoses, CoronaryView official trial listing → -
Terminated NCT NCT03600961
BIOFLOW-SV Portugal Registry
Biotronik AG 173 participants Est. completion 2021-12-21 4 sitesOther conditions: Ischemic Heart DiseaseView official trial listing → -
Completed NCT NCT03605927
CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 45 participants Est. completion 2023-07-25 3 sites Stand-aloneOther conditions: Graft-versus-host-disease, GVHD, GVHD, AcuteView official trial listing → -
Terminated NCT NCT03610347
Paclitaxel Eluting Balloon After Bare Metal Stent Implantation vs. Drug-Eluting Stent in St Elevation Myocardial Infarction
Not yet reported Fundacion Investigacion Interhospitalaria Cardiovascular 199 participants Est. completion 2020-03-31 16 sitesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT03616132
A First-in-Man Study to Evaluate the Feasibility and Safety of Sirolimus-eluting Iron Bioresorbable Coronary Scaffold System
Not yet reported Lifetech Scientific (Shenzhen) Co., Ltd. 15 participants Est. completion 2023-03-30 2 sites Stand-aloneOther conditions: Single Coronary Vessel DiseaseView official trial listing → -
Active, not recruiting NCT NCT03616587
Study of AZD9833 Alone or in Combination in Women With Advanced Breast Cancer.
Not yet reported AstraZeneca 396 participants Est. completion 2027-06-24 17 sitesOther conditions: ER+ HER2- Advanced Breast CancerView official trial listing → -
Completed NCT NCT03618355
Trial of eRapa in Prostate Cancer Patients
Not yet reported Rapamycin Holdings, Inc. dba Emtora Biosciences 15 participants Est. completion 2019-12-02 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Active, not recruiting NCT NCT03621501
Direct Complete Versus Staged Complete Revascularization in Patients Presenting With Acute Coronary Syndromes and Multivessel Disease
Not yet reported Erasmus Medical Center 1525 participants Est. completion 2026-10-31 1 siteOther conditions: Acute Coronary SyndromeView official trial listing → -
Status unknown NCT NCT03629847
Treatment of Neuroendocrine Tumors (NETs) With Combination of Everolimus and Radiolabeled Somatostatin Analogue
Not yet reported, Not yet reported King Faisal Specialist Hospital & Research Center 30 participants Est. completion 2018-12 1 siteOther conditions: Neuroendocrine TumorsView official trial listing → -
Withdrawn NCT NCT03632317
A Study of Panobinostat in Combination With Everolimus for Children and Young Adults With Gliomas
Not yet reported University of Michigan Rogel Cancer Center Est. completion 2025-10 1 siteOther conditions: Glioma, Diffuse Intrinsic Pontine GliomaView official trial listing → -
Completed NCT NCT03634020
DynamX Sirolimus Study Sirolimus Eluting Coronary Bioadaptor System
Not yet reported Elixir Medical Corporation 44 participants Est. completion 2021-03-08 7 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT03646240
ABI-009 (Nab-rapamycin) for Surgically-Refractory Epilepsy (RaSuRE)
Not yet reported Seattle Children's Hospital 14 participants Est. completion 2022-12-31 1 siteOther conditions: Epilepsy IntractableView official trial listing → -
Terminated NCT NCT03654040
Liver Transplantation With Tregs at UCSF
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 42 participants Est. completion 2023-03-06 1 siteOther conditions: Liver TransplantView official trial listing → -
Withdrawn NCT NCT03657420
Safety and Efficacy of ABI-009 (Nab-rapamycin) in Combination With Pomalidomide and Dexamethasone for Relapsed and Refractory Multiple Myeloma
Not yet reported Massachusetts General Hospital Est. completion 2024-09-30 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT03659136
The XENERA™ 1 Study Tests Xentuzumab in Combination With Everolimus and Exemestane in Women With Hormone Receptor Positive and HER2-negative Breast Cancer That Has Spread
Not yet reported Boehringer Ingelheim 103 participants Est. completion 2022-05-11 54 sitesOther conditions: Breast NeoplasmsView official trial listing → -
Status unknown NCT NCT03660202
Trial for MicroPort's Firesorb BVS: FUTURE-III
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 1200 participants Est. completion 2024-06 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT03660930
Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas
Not yet reported, Not yet reported University of Washington 19 participants Est. completion 2024-07-31 1 site Stand-aloneOther conditions: Advanced Soft Tissue Sarcoma, Locally Advanced Soft Tissue Sarcoma, Metastatic Soft Tissue SarcomaView official trial listing → -
Status unknown NCT NCT03662412
Study of Sirolimus in Patients With Advanced Pancreatic Cancer
Not yet reported, Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 36 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: Pancreatic CancerView official trial listing → -
Completed NCT NCT03666208
Sirolimus Coated Angioplasty Balloon in the Salvage of Thrombosed Arteriovenous Graft
Not yet reported Singapore General Hospital 20 participants Est. completion 2019-09-02 1 site Stand-aloneOther conditions: End Stage Renal Failure on Dialysis, Arteriovenous Graft OcclusionView official trial listing → -
Completed NCT NCT03667313
Treatment of In-Stent Restenosis 2 Study
Not yet reported University Hospital Ostrava 200 participants Est. completion 2021-12-31 1 site Stand-aloneOther conditions: Coronary RestenosisView official trial listing → -
Terminated NCT NCT03670030
A Study to testABI-009 in Patients With Metastatic, Unresectable, Low or Intermediate Grade Neuroendocrine Tumors of the Lung or Gastroenteropancreatic System
Not yet reported Robert Ramirez 5 participants Est. completion 2021-02-26 1 siteOther conditions: Neuroendocrine TumorsView official trial listing → -
Status unknown NCT NCT03688191
Study of Sirolimus in CTD-TP in China
Not yet reported Peking Union Medical College Hospital 20 participants Est. completion 2019-09-30 1 site Stand-aloneOther conditions: Connective Tissue Diseases, ThrombocytopeniaView official trial listing → -
Completed NCT NCT03696355
Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas
Not yet reported St. Jude Children's Research Hospital 27 participants Est. completion 2022-09-04 1 siteOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Active, not recruiting NCT NCT03697408
Itacitinib + Everolimus in Hodgkin Lymphoma
Not yet reported, Not yet reported University of Pennsylvania 23 participants Est. completion 2027-06 1 siteOther conditions: Classical Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT03711929
LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the Eye
Not yet reported Santen Inc. 145 participants Est. completion 2022-06-14 65 sitesOther conditions: Non Infectious UveitisView official trial listing → -
Status unknown NCT NCT03716011
A Postmarket Clinical Trial for EXCROSSAL Stent in CAD Patients With 3-month DAPT or 12-month DAPT
Not yet reported JW Medical Systems Ltd 2700 participants Est. completion 2025-12-20 1 siteCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT03716102
OPTIMIZE Sirolimus-Eluting Coronary Stent Systems Pharmacokinetics (PK) Study
Not yet reported Svelte Medical Systems, Inc. 12 participants Est. completion 2021-07-15 2 sites Stand-aloneOther conditions: Acute Coronary SyndromeView official trial listing → -
Status unknown NCT NCT03721614
Clinical Study Comparing Single Long BioMimeTM Morph Coronary Stent System vs. Two Overlapping Xience Family Coronary Stent Systems in the Treatment of Patients With Long de Novo Lesions.
Not yet reported Meril Life Sciences Pvt. Ltd. 200 participants Est. completion 2022-06-22 Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT03730142
A Study of WXFL10030390 in Patients With Advanced Solid Tumors or Lymphoma
Not yet reported Shanghai Jiatan Pharmatech Co., Ltd 82 participants Est. completion 2020-07-25 1 siteOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT03730428
Everolimus Related Pneumonitis in MBC
Fudan University 86 participants Est. completion 2020-06-15 1 siteOther conditions: Everolimus, PneumonitisView official trial listing → -
Completed NCT NCT03732248
Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders
Not yet reported Medical University of South Carolina 21 participants Est. completion 2020-01-20 1 siteAlcohol use disorderView official trial listing → -
Terminated NCT NCT03740100
Single-arm Study With Bimiralisib in Patients With HNSCC Harboring NOTCH1 Loss of Function Mutations
Not yet reported M.D. Anderson Cancer Center 8 participants Est. completion 2020-12-09 1 siteOther conditions: HNSCCView official trial listing → -
Active, not recruiting NCT NCT03740334
Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL
Not yet reported Dana-Farber Cancer Institute 45 participants Est. completion 2027-04-30 12 sitesOther conditions: Acute Lymphoblastic Leukemia ALLView official trial listing → -
Withdrawn NCT NCT03747328
ABI-009 (Nab-sirolimus) in Patients With Genetically-confirmed Leigh or Leigh-like Syndrome
Not yet reported Aadi Bioscience, Inc. Est. completion 2025-03-31 Stand-aloneOther conditions: Leigh SyndromeView official trial listing → -
Completed NCT NCT03765944
Bioequivalence Study of NPC-12 (Sirolimus) Granules and Tablets
Not yet reported Nobelpharma 10 participants Est. completion 2018-12-29 1 siteOther conditions: Bioequivalence StudyView official trial listing → -
Status unknown NCT NCT03767660
Efficacy of Rapamycin (Sirolimus) in the Treatment of BRBNS, Hereditary or Sporadic Venous Malformation
Not yet reported Peking Union Medical College Hospital 20 participants Est. completion 2022-07-01 1 siteOther conditions: Blue Rubber Bleb Nevus Syndrome, Venous MalformationView official trial listing → -
Active, not recruiting NCT NCT03778996
SM-88 Maintenance Therapy for Advanced Ewing's Sarcoma and as Salvage Therapy for Sarcoma
Not yet reported Sarcoma Oncology Research Center, LLC 31 participants Est. completion 2028-03-31 1 site Stand-aloneOther conditions: Sarcoma, Ewing, SarcomaView official trial listing → -
Status unknown NCT NCT03780192
INSPIRON Sirolimus Eluting Stent Performance in Bifurcation Coronary Arteries Treated Using Provisional Technique
Scitech Produtos Medicos SA 80 participants Est. completion 2022-02-15 1 siteCardiovascular disease Other conditions: Bifurcation LesionView official trial listing → -
Status unknown NCT NCT03781050
Efficacy of Rapamycin (Sirolimus) in the Treatment of Peutz-Jeghers Syndrome
Not yet reported Peking Union Medical College Hospital 10 participants Est. completion 2022-07-01 1 siteOther conditions: Peutz-Jeghers SyndromeView official trial listing → -
Status unknown NCT NCT03785431
Vascular Healing After Implantation of FANTOM Bioresorbable Scaffold in STEMI: A FANTOM STEMI Study
Not yet reported Medical University of Warsaw 20 participants Est. completion 2022-06-06 1 siteCardiovascular disease Other conditions: STEMI, Bioresorbable ScaffoldView official trial listing → -
Active, not recruiting NCT NCT03797196
RCT Comparing Immunosuppressive Regimens in Elderly Renal Transplant Recipients
Not yet reported University Medical Center Groningen 374 participants Est. completion 2026-12 7 sitesOther conditions: Renal Transplant Recipients, Elderly Patients, ImmunosuppressionView official trial listing → -
Status unknown NCT NCT03805399
FUSCC Refractory TNBC Umbrella (FUTURE)
Not yet reported, Not yet reported Fudan University 140 participants Est. completion 2022-12-01 1 siteOther conditions: Triple-negative Breast CancerView official trial listing → -
Approved For Marketing NCT NCT03817515
Expanded Access for ABI-009 in Patients With Advanced PEComa and Patients With a Malignancy With Relevant Genetic Mutations or mTOR Pathway Activation
Aadi Bioscience, Inc.Other conditions: PEComa, Malignant, TSC1, TSC2, mTOR Pathway AbberationView official trial listing → -
Completed NCT NCT03826628
Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex
Not yet reported, Not yet reported Dermatology Specialties Limited Partnership 107 participants Est. completion 2022-09-01 17 sitesOther conditions: Facial Angiofibroma, Tuberous SclerosisView official trial listing → -
Completed NCT NCT03834740
A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection
Not yet reported St. Joseph's Hospital and Medical Center, Phoenix 27 participants Est. completion 2022-02-18 3 sitesOther conditions: Glioblastoma Multiforme, Glioma of BrainView official trial listing → -
Terminated NCT NCT03839940
Dexamethasone in Reducing Everolimus-Induced Oral Stomatitis in Patients With Cancer
Not yet reported Alliance for Clinical Trials in Oncology 39 participants Est. completion 2022-08-03 319 sitesOther conditions: Malignant NeoplasmView official trial listing → -
Status unknown NCT NCT03842813
Safety and Performance Assessment of Drug-Eluting Stent CRE8 in Diabetic Patients
Alvimedica Medical Technologies France 1030 participants Est. completion 2022-07 22 sitesOther conditions: Diabetes, CoronaropathyView official trial listing → -
Status unknown NCT NCT03866681
Sirolimus Combined With Low-dose Warfarin for the Treatment of Refractory PNH
Not yet reported Peking Union Medical College Hospital 40 participants Est. completion 2022-04-01 1 site Stand-aloneOther conditions: Paroxysmal Nocturnal HemoglobinuriaView official trial listing → -
Completed NCT NCT03871127
Ten-Year Outcomes of PRE-COMBAT Trial
Seung-Jung Park 600 participants Est. completion 2020-02-24 9 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT03871361
Abatacept in Patients With Birdshot HLA A29 Uveitis
Not yet reported Universitaire Ziekenhuizen KU Leuven 15 participants Est. completion 2023-12-01 1 site Stand-aloneOther conditions: Eye Diseases, UveitisView official trial listing → -
Completed NCT NCT03871972
Umbilical Cord Blood Transfusion in Progeria Syndrome
Not yet reported, Not yet reported Bundang CHA Hospital 2 participants Est. completion 2020-06-01 1 site Stand-aloneOther conditions: Hutchinson-Gilford Progeria SyndromeView official trial listing → -
Completed NCT NCT03877809
Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients
Not yet reported Rare Partners srl Impresa Sociale 26 participants Est. completion 2022-04-30 2 sites Stand-aloneOther conditions: Beta-ThalassemiaView official trial listing → -
Terminated NCT NCT03878524
Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial
Not yet reported OHSU Knight Cancer Institute 2 participants Est. completion 2020-12-10 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Anatomic Stage IV Breast Cancer AJCC v8, Anemia, Ann Arbor Stage III Hodgkin Lymphoma, Ann Arbor Stage III Non-Hodgkin Lymphoma, Ann Arbor Stage IV Hodgkin Lymphoma, Ann Arbor Stage IV Non-Hodgkin Lymphoma, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Castration-Resistant Prostate Carcinoma, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid System Neoplasm, Locally Advanced Pancreatic Adenocarcinoma, Metastatic Breast Carcinoma, Metastatic Malignant Solid Neoplasm, Metastatic Pancreatic Adenocarcinoma, Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Primary Myelofibrosis, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Hematologic Malignancy, Recurrent Hodgkin Lymphoma, Recurrent Myelodysplastic Syndrome, Recurrent Myelodysplastic/Myeloproliferative Neoplasm, Recurrent Myeloproliferative Neoplasm, Recurrent Non-Hodgkin Lymphoma, Recurrent Plasma Cell Myeloma, Recurrent Small Lymphocytic Lymphoma, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Chronic Lymphocytic Leukemia, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Chronic Myelomonocytic Leukemia, Refractory Hematologic Malignancy, Refractory Hodgkin Lymphoma, Refractory Malignant Solid Neoplasm, Refractory Myelodysplastic Syndrome, Refractory Myelodysplastic/Myeloproliferative Neoplasm, Refractory Non-Hodgkin Lymphoma, Refractory Plasma Cell Myeloma, Refractory Primary Myelofibrosis, Refractory Small Lymphocytic Lymphoma, Stage II Pancreatic Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8, Unresectable Pancreatic AdenocarcinomaView official trial listing → -
Status unknown NCT NCT03886233
Treatment Outcome of Uveitis in Autoimmune Diseases
Assiut University 1 participants Est. completion 2021-02Other conditions: Autoimmune UveitisView official trial listing → -
Status unknown NCT NCT03901001
Adjunctive Sirolimus and Oseltamivir Versus Oseltamivir Alone for Treatment of Influenza
Not yet reported Chinese University of Hong Kong 160 participants Est. completion 2025-12-31 1 siteOther conditions: InfluenzaView official trial listing → -
Completed NCT NCT03908450
Treatment of Coronary De-novo Stenosis by a Sirolimus Coated Balloon or a Paclitaxel Coated Balloon Catheter
Not yet reported InnoRa GmbH 70 participants Est. completion 2023-07-31 4 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT03910452
Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 4 participants Est. completion 2034-06-15 1 site Stand-aloneOther conditions: Chronic Granulomatous DiseaseView official trial listing → -
Status unknown NCT NCT03913832
TReAtmeNt of Small Coronary Vessels: MagicTouch Sirolimus Coated Balloon
Not yet reported Concept Medicals BV 121 participants Est. completion 2023-09-10 6 sites Stand-aloneCardiovascular disease Other conditions: DCBView official trial listing → -
Status unknown NCT NCT03916432
HELIOS China Registry: Evaluation of the HELIOS Stent in a 'Real-World' Patient Population
Not yet reported Xijing Hospital 3000 participants Est. completion 2025-12-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT03918070
Observatory to Assess the Yukon Choice PC & the Yukon Chrome PC Sirolimus Eluting Bioabsorbable Polymer Stents Systems
Translumina GmbH 2722 participants Est. completion 2024-05-24 19 sitesOther conditions: CoronaropathyView official trial listing → -
Active, not recruiting NCT NCT03922724
Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma
Not yet reported National Cancer Institute (NCI) 91 participants Est. completion 2030-10-31 2 sites Stand-aloneOther conditions: Peripheral T-cell Lymphomas, Lymphoproliferative Disorders, Immune System DiseasesView official trial listing → -
Status unknown NCT NCT03932539
Improving Immunosuppressive Therapy in Heart Transplantation
Fondazione IRCCS Policlinico San Matteo di Pavia 25 participants Est. completion 2021-12 4 sitesOther conditions: Rejection Heart Transplant, ImmunosuppressionView official trial listing → -
Active, not recruiting NCT NCT03933904
Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease
Not yet reported University of Pennsylvania 7 participants Est. completion 2027-06-30 2 sites Stand-aloneOther conditions: Castleman Disease, Castleman's Disease, MulticentricView official trial listing → -
Terminated NCT NCT03942601
Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization
Not yet reported Mercator MedSystems, Inc. 10 participants Est. completion 2021-04-30 11 sitesOther conditions: Peripheral Arterial DiseaseView official trial listing → -
Status unknown NCT NCT03942926
The Efficacy and Safety of Sirolimus for Plastic Bronchitis
Not yet reported Peking Union Medical College Hospital 10 participants Est. completion 2020-05-05 1 site Stand-aloneOther conditions: Plastic BronchitisView official trial listing → -
Terminated NCT NCT03946774
Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling
Not yet reported Washington University School of Medicine 21 participants Est. completion 2023-05-04 1 siteOther conditions: Dietary ProteinView official trial listing → -
Active, not recruiting NCT NCT03950609
Lenvatinib and Everolimus in Treating Patients With Advanced, Unresectable Carcinoid Tumors
Not yet reported M.D. Anderson Cancer Center 36 participants Est. completion 2028-03-30 1 siteOther conditions: Advanced Carcinoid Tumor, Digestive System Neuroendocrine Neoplasm, Multiple Endocrine Neoplasia Type 1, Neuroendocrine Neoplasm, Unresectable Carcinoid TumorView official trial listing → -
Active, not recruiting NCT NCT03952273
Sort Out XI - Combo Stent Versus BioMatrix Alpha Stent
Not yet reported Phillip Freeman 3141 participants Est. completion 2030-11-30 2 sitesCardiovascular diseaseView official trial listing → -
Terminated NCT NCT03963024
Treosulfan-TMI Conditioning and Rapamycin GvHD Prophylaxis Before Allo-HSCT
Not yet reported IRCCS San Raffaele 9 participants Est. completion 2019-01-31 1 siteOther conditions: Irradiated Bone Marrow, Transplant-Related Hematologic Malignancy, Leukemia, Acute, Multiple Myeloma, Graft Vs Host DiseaseView official trial listing → -
Completed NCT NCT03972462
NPC-12G Gel 0.2% Sirolimus PK Bridging Study
Not yet reported Nobelpharma 12 participants Est. completion 2019-06-17 1 site Stand-aloneOther conditions: Bioavailability StudyView official trial listing → -
Completed NCT NCT03972592
Topical Sirolimus in Cutaneous Lymphatic Malformations
Not yet reported University Hospital, Tours 55 participants Est. completion 2024-08-14 17 sites Stand-aloneOther conditions: Vascular Malformations, Lymphatic MalformationView official trial listing → -
Active, not recruiting NCT NCT03983850
Optimizing PTCy Dose and Timing
Not yet reported, Not yet reported National Cancer Institute (NCI) 105 participants Est. completion 2026-10-26 1 site Stand-aloneOther conditions: Graft Versus Host Disease, Hematologic NeoplasmsView official trial listing → -
Status unknown NCT NCT03987152
Treatment of Congenital Vascular Malformations Using Sirolimus: Improving Quality of Life
Not yet reported Radboud University Medical Center 75 participants Est. completion 2023-03-01 1 siteOther conditions: Vascular MalformationsView official trial listing → -
Status unknown NCT NCT04014595
PREPARE-CALC-COMBO: Severely Calcified Coronary Lesions Prepared With Rotational Atherectomy and Modified Balloons
Segeberger Kliniken GmbH 100 participants Est. completion 2025-07-31 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT04017364
Treatment of Coronary De-novo Stenosis by a Sirolimus Coated Balloon or a Paclitaxel Coated Balloon Catheter Malaysia
Not yet reported InnoRa GmbH 70 participants Est. completion 2021-01-31 6 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT04047576
Study of Sirolimus in Idiopathic Retroperitoneal Fibrosis
Not yet reported, Not yet reported Peking University International Hospital 64 participants Est. completion 2026-06-28 1 site Stand-aloneOther conditions: Retroperitoneal FibrosisView official trial listing → -
Completed NCT NCT04049552
RAPA-Keloid Study of Keloid Regression
Not yet reported The University of Texas Health Science Center at San Antonio 4 participants Est. completion 2021-05-02 1 siteOther conditions: KeloidView official trial listing → -
Completed NCT NCT04066114
Treg Modulation With CD28 and IL-6 Receptor Antagonists
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 24 participants Est. completion 2023-09-14 7 sitesOther conditions: Living-Donor Kidney Transplant, Kidney Transplant RecipientsView official trial listing → -
Completed NCT NCT04071782
Investigating the Safety and Efficacy of the Treatment With the Selution Sirolimus Coated Balloon in TASC C and D Tibial Occlusive Disease in Patients With Critical Limb Ischemia From Singapore
Not yet reported Singapore General Hospital 25 participants Est. completion 2021-01-30 1 site Stand-aloneOther conditions: Critical Limb IschemiaView official trial listing → -
Completed NCT NCT04077515
Safety and Efficacy of Low-dose Sirolimus to Kaposiform Hemangioendothelioma
Not yet reported Children's Hospital of Fudan University 92 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: Hemangioma, Kaposiform HemangioendotheliomaView official trial listing → -
Completed NCT NCT04094675
Sirolimus for Cowden Syndrome With Colon Polyposis
Not yet reported Ohio State University 5 participants Est. completion 2025-06-05 1 site Stand-aloneOther conditions: PTEN Gene Mutation, PTEN Hamartoma Tumor Syndrome, PTEN Hamartoma Syndrome, Cowden Syndrome, Bannayan Syndrome, Bannayan Zonana Syndrome, PolyposisView official trial listing → -
Completed NCT NCT04104438
Examination of Immunosuppression Adjustment Impact on Kidney Function in Liver Transplant
Not yet reported Fady M Kaldas, M.D., F.A.C.S. 71 participants Est. completion 2024-09-30 1 siteOther conditions: Asses Immunosuppression Modulation on Renal Recovery Post LTView official trial listing → -
Completed NCT NCT04107298
Safety and Feasibility of Surmodics SUNDANCE™ Drug Coated Balloon
Not yet reported SurModics, Inc. 35 participants Est. completion 2024-01-30 8 sites Stand-aloneOther conditions: Peripheral Arterial Disease, Critical Lower Limb IschemiaView official trial listing → -
Completed NCT NCT04115800
Liposomal Sirolimus in Dry Eye Disease
Not yet reported Instituto de Oftalmología Fundación Conde de Valenciana 52 participants Est. completion 2020-08-01 1 site Stand-aloneOther conditions: Dry EyeView official trial listing → -
Terminated NCT NCT04118556
Decidua Stroma Cells for Steroid Resistent Acute Graft-versus-host Disease After Allo-HSCT
Not yet reported Mats Remberger 12 participants Est. completion 2026-04-29 4 sitesOther conditions: GVHD, AcuteView official trial listing → -
Active, not recruiting NCT NCT04127578
Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)
Not yet reported, Not yet reported Prevail Therapeutics 32 participants Est. completion 2031-08-31 15 sites Stand-aloneOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT04128722
TOPical Sirolimus in linGUal Microcystic Lymphatic Malformation -TOPGUN
Not yet reported University Hospital, Tours 12 participants Est. completion 2025-01-08 2 sites Stand-aloneOther conditions: Lingual Microcystic Lymphatic MalformationsView official trial listing → -
Status unknown NCT NCT04135989
Personalized Vs. Standard Duration of Dual Antiplatelet Therapy and New-generation Polymer-Free vs- Biodegradable-Polymer DES
Not yet reported Federico II University 2106 participants Est. completion 2024-10-24 13 sitesCardiovascular disease Other conditions: Acute Coronary Syndrome, Chronic Coronary SyndromeView official trial listing → -
Completed NCT NCT04138238
Cruz HBR Registry - Post-market Registry to Evaluate the Safety and Efficacy of the Supraflex Cruz Stent
Sahajanand Medical Technologies Limited 1200 participants Est. completion 2022-05-31 26 sitesCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT04139915
Effect of RTB101 on Illness Associated With Respiratory Tract Infections in the Elderly
Not yet reported Restorbio Inc. Est. completion 2019-11-15Other conditions: Clinically Symptomatic Respiratory IllnessView official trial listing → -
Status unknown NCT NCT04150016
In-stent Repair and Vessel Reaction of STEMI Patients With OCT
Not yet reported Xijing Hospital 44 participants Est. completion 2021-12-01 1 site Stand-aloneCardiovascular disease Other conditions: Drug-eluting Stents, Percutaneous Coronary Intervention, Optical Coherence TomographyView official trial listing → -
Active, not recruiting NCT NCT04157153
First in Men Study: BIOMAG-I
Not yet reported Biotronik AG 116 participants Est. completion 2027-02 14 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT04161144
Enhancing Self Regulation Among Smokers
Not yet reported Medical University of South Carolina 22 participants Est. completion 2019-12-20 1 siteOther conditions: Smoking Cessation, Smoking, Cigarette, Nicotine DependenceView official trial listing → -
Status unknown NCT NCT04168944
Lenvatinib Following Liver Transplantation in Patients With High-Risk Hepatocellular Carcinoma
Not yet reported, Not yet reported RenJi Hospital 108 participants Est. completion 2022-09 Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT04172922
Topical Rapamycin/Sirolimus for Complicated Vascular Anomalies and Other Susceptible Lesions
Not yet reported Nemours Children's Clinic 5 participants Est. completion 2024-02-15 2 sites Stand-aloneOther conditions: Vascular AnomalyView official trial listing → -
Completed NCT NCT04175626
Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions
Biotronik, Inc. 556 participants Est. completion 2026-01-08 33 sitesCardiovascular disease Other conditions: Atherosclerosis, Coronary, Myocardial Ischemia, Ischemic Heart Disease, Acute Coronary Syndrome, Angina PectorisView official trial listing → -
Completed NCT NCT04176380
RAPA-201 T Cell Therapy for Relapsed, Refractory Multiple Myeloma
Not yet reported Rapa Therapeutics LLC 15 participants Est. completion 2023-06-06 1 siteOther conditions: Relapsed, Refractory Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT04177004
Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant
Not yet reported City of Hope Medical Center 52 participants Est. completion 2026-10-27 1 site Stand-aloneOther conditions: Allogeneic Hematopoietic Stem Cell Transplant Recipient, Hematopoietic and Lymphoid Cell NeoplasmView official trial listing → -
Completed NCT NCT04177095
Immune Monitoring to Facilitate Belatacept Monotherapy
Not yet reported Massachusetts General Hospital 17 participants Est. completion 2023-06-01 1 site Stand-aloneOther conditions: Kidney Transplant Rejection, ImmunosuppressionView official trial listing → -
Status unknown NCT NCT04179045
A Registry Trial of The Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System
Not yet reported Shanghai Bio-heart Biological Technology Co., Ltd. 785 participants Est. completion 2026-07 5 sitesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT04185831
A MolEcularly Guided Anti-Cancer Drug Off-Label Trial
Not yet reported Uppsala University Hospital 167 participants Est. completion 2024-10 3 sitesOther conditions: Solid TumorView official trial listing → -
Active, not recruiting NCT NCT04185883
Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)
Not yet reported Amgen 610 participants Est. completion 2027-12-05 90 sitesOther conditions: Advanced Solid Tumors, Kirsten Rat Sarcoma (KRAS) pG12C MutationView official trial listing → -
Active, not recruiting NCT NCT04188548
A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer
Not yet reported Eli Lilly and Company 379 participants Est. completion 2027-12 74 sitesOther conditions: Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer, Endometrial CancerView official trial listing → -
Active, not recruiting NCT NCT04192747
The Elixir Bioadaptor vs. The Onyx Stent in De Novo Native Coronary Arteries
Not yet reported Elixir Medical Corporation 445 participants Est. completion 2027-02-28 36 sitesCardiovascular disease Other conditions: Coronary Artery Stenosis, Coronary Disease, Coronary StenosisView official trial listing → -
Active, not recruiting NCT NCT04195750
A Study of Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005)
Not yet reported Merck Sharp & Dohme LLC 755 participants Est. completion 2026-09-17 172 sitesOther conditions: Carcinoma, Renal CellView official trial listing → -
Completed NCT NCT04200911
Cognition, Age, and RaPamycin Effectiveness - DownregulatIon of thE mTor Pathway
Not yet reported The University of Texas Health Science Center at San Antonio 10 participants Est. completion 2022-01-13 1 site Stand-aloneOther conditions: Cognitive Impairment, Mild, Alzheimer DiseaseView official trial listing → -
Completed NCT NCT04202172
Functional Assessment of the Infart-related Artery With Bioactive and Polymer-free Coronary Stents (The FUNCOMBO Trial)
Not yet reported Institut d'Investigació Biomèdica de Bellvitge 60 participants Est. completion 2020-09-01 1 siteCardiovascular disease Other conditions: Endothelial Dysfunction, Coronary Microvascular DiseaseView official trial listing → -
Terminated NCT NCT04203901
Dendritic Cell Immunotherapy Plus Standard Treatment of Advanced Renal Cell Carcinoma
Not yet reported CoImmune 16 participants Est. completion 2023-09-28 9 sitesOther conditions: Advanced Renal Cell CarcinomaView official trial listing → -
Status unknown NCT NCT04212702
ESR1 Mutations in Asian ER+ Metastatic Breast Cancer on Hormonal Therapy-based Treatments
National Taiwan University Hospital 123 participants Est. completion 2021-12-31 2 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT04229004
A Multi-center Trial to Evaluate Multiple Regimens in Metastatic Pancreatic Cancer
Not yet reported Pancreatic Cancer Action Network 502 participants Est. completion 2025-02-05 25 sites Stand-aloneOther conditions: Metastatic Pancreatic Cancer, Metastatic Pancreatic AdenocarcinomaView official trial listing → -
Active, not recruiting NCT NCT04230499
Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance
Not yet reported Rapamycin Holdings Inc. 30 participants Est. completion 2025-03 4 sitesOther conditions: Familial Adenomatous PolyposisView official trial listing → -
Status unknown NCT NCT04236609
Randomized Comparison of Abluminus DES+ Sirolimus-Eluting Stents Versus Everolimus-Eluting Stents in Coronary Artery Disease Patients With Diabetes Mellitus Global
Not yet reported Concept Medical Inc. 3050 participants Est. completion 2024-09-30 90 sitesCardiovascular disease Other conditions: Diabetes, Acute Coronary SyndromeView official trial listing → -
Active, not recruiting NCT NCT04238546
Major Adverse Limb Events in Patients With Femoro-popliteal and Below-the-knee Peripheral Arterial Disease Treated With Either Sirolimus-coated Balloon or Standard Uncoated Balloon Angioplasty
Not yet reported Nils Kucher 1200 participants Est. completion 2029-12-31 2 sites Stand-aloneOther conditions: Peripheral Arterial DiseaseView official trial listing → -
Completed NCT NCT04240444
Sirolimus-Coated Balloon Versus Paclitaxel-Coated Balloon for the Treatment of Coronary In-Stent Restenosis
Not yet reported B. Braun Medical International Trading Company Ltd. 260 participants Est. completion 2022-08-30 16 sites Stand-aloneCardiovascular disease Other conditions: In Stent RestenosisView official trial listing → -
Status unknown NCT NCT04247750
Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients (THALA-RAP)
Not yet reported Università degli Studi di Ferrara 45 participants Est. completion 2022-04-30 4 sites Stand-aloneOther conditions: Beta-ThalassemiaView official trial listing → -
Terminated NCT NCT04258423
Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function
Not yet reported Indiana University 4 participants Est. completion 2020-06-27 1 siteOther conditions: Kidney FailureView official trial listing → -
Active, not recruiting NCT NCT04280029
SELUTION SLR™ 014 In-stent Restenosis
Not yet reported M.A. Med Alliance S.A. 418 participants Est. completion 2029-08 48 sites Stand-aloneOther conditions: Coronary RestenosisView official trial listing → -
Terminated NCT NCT04305444
Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas
Not yet reported Zhejiang DTRM Biopharma 55 participants Est. completion 2024-12-31 8 sitesOther conditions: Relapsed Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, Richter's TransformationView official trial listing → -
Completed NCT NCT04323033
Safety and Efficacy of Peripheral, Cobalt-chromium Sirolimus Eluting Stent (PERS) Versus Cobalt-chromium Stent (Neptune C)
Not yet reported Balton Sp.zo.o. 40 participants Est. completion 2021-11-09 3 sites Stand-aloneOther conditions: Peripheral Arterial DiseaseView official trial listing → -
Completed NCT NCT04324372
Clinical Study of HEC68498 in Patients With Advanced Refractory Solid Tumors
Not yet reported Sunshine Lake Pharma Co., Ltd. 12 participants Est. completion 2021-03-26 1 siteOther conditions: Advanced Refractory Solid TumorsView official trial listing → -
Withdrawn NCT NCT04324411
Sirolimus Combined With ATRA for the Treatment of Auto-Immune Anemia
Not yet reported Peking Union Medical College Hospital Est. completion 2023-09-01 1 site Stand-aloneOther conditions: Autoimmune AnemiaView official trial listing → -
Completed NCT NCT04327609
SAVE Trial - Use of the Selution Sirolimus Eluting Balloon for Dysfunctional AV accEss Treatment Indications
Not yet reported M.A. Med Alliance S.A. 84 participants Est. completion 2025-07-23 3 sites Stand-aloneOther conditions: AV FistulaView official trial listing → -
Completed NCT NCT04339062
Cemiplimab in AlloSCT/SOT Recipients With CSCC
Not yet reported, Not yet reported Dana-Farber Cancer Institute 12 participants Est. completion 2025-03-01 1 site Stand-aloneOther conditions: Cutaneous Squamous Cell Carcinoma, Advanced CancerView official trial listing → -
Completed NCT NCT04339101
Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation
Not yet reported City of Hope Medical Center 59 participants Est. completion 2025-10-09 1 site Stand-aloneOther conditions: Acute Leukemia, Hematologic and Lymphocytic Disorder, Myelodysplastic Syndrome, Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Completed NCT NCT04341675
Sirolimus Treatment in Hospitalized Patients With COVID-19 Pneumonia
Not yet reported University of Cincinnati 32 participants Est. completion 2020-09-15 2 sitesOther conditions: COVID-19View official trial listing → -
Status unknown NCT NCT04345965
Sirolimus Eluting Balloon Utilization for Treatment of Vasculogenic Erectile Dysfunction
Clinica San Gaudenzio 100 participants Est. completion 2023-12-01 1 siteOther conditions: Erectile DysfunctionView official trial listing → -
Terminated NCT NCT04348292
Sirolimus and Durvalumab for the Treatment of Stage I-IIIA Non-small Cell Lung Cancer
Not yet reported Emory University 3 participants Est. completion 2022-11-04 1 site Stand-aloneOther conditions: Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8, Stage IA3 Lung Cancer AJCC v8, Stage IB Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8View official trial listing → -
Status unknown NCT NCT04355858
Molecularly Targeted Umbrella Study in Luminal Advanced Breast Cancer
Not yet reported Fudan University 319 participants Est. completion 2025-04-01 1 siteOther conditions: Breast Cancer, Metastatic CancerView official trial listing → -
Active, not recruiting NCT NCT04362293
Reduced Intensity Transplantation for Severe Sickle Cell Disease
Not yet reported St. Jude Children's Research Hospital 46 participants Est. completion 2029-08-01 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT04368091
Clinical Use and Safety of the Xtreme Touch (Magic Touch PTA)- Neo Sirolimus Coated PTA Balloon Catheter in the Treatment of Infrainguinal Peripheral Arterial Disease
Concept Medical Inc. 50 participants Est. completion 2021-12-30 1 siteOther conditions: Peripheral Artery Disease, AtherosclerosisView official trial listing → -
Withdrawn NCT NCT04370795
Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) Est. completion 2025-11-26 1 siteOther conditions: Severe Combined Immune Deficiency (SCID)View official trial listing → -
Withdrawn NCT NCT04371640
Sirolimus in COVID-19 Phase 1
Not yet reported Walter K. Kraft Est. completion 2021-07-30 1 siteOther conditions: SARS-CoV-2, Covid-19View official trial listing → -
Withdrawn NCT NCT04374903
Hydroxychloroquine in Combination With Sirolimus and Dexamethasone for Treating COVID-19 Patients
Not yet reported King Hussein Cancer Center Est. completion 2022-04-01 1 site Stand-aloneOther conditions: COVID-19 PatientsView official trial listing → -
Active, not recruiting NCT NCT04375813
Trial of Encapsulated Rapamycin (eRapa) for Bladder Cancer Prevention
Not yet reported Robert Svatek 166 participants Est. completion 2027-07 2 sitesOther conditions: Non-muscle Invasive Bladder CancerView official trial listing → -
Completed NCT NCT04388371
Glutamine PET Imaging in LAM
Not yet reported Vanderbilt University Medical Center 5 participants Est. completion 2021-08-10 1 site Stand-aloneOther conditions: Lymphangioleiomyomatosis (LAM)View official trial listing → -
Active, not recruiting NCT NCT04390672
Multivessel TALENT
Not yet reported National University of Ireland, Galway, Ireland 1550 participants Est. completion 2026-09 1 site Stand-aloneCardiovascular disease Other conditions: Myocardial Ischemia, Coronary Disease, Heart Diseases, Arterial Occlusive Diseases, Vascular DiseasesView official trial listing → -
Terminated NCT NCT04393454
Study to Evaluate the Efficacy and Safety of Sirolimus in Subjects With Metastatic, Mismatch Repair Deficient Solid Tumors After Immunotherapy
Not yet reported Albert Einstein College of Medicine 6 participants Est. completion 2023-05-16 1 site Stand-aloneOther conditions: Metastatic dMMR Solid Cancer, Solid Tumor, Cancer, Metastatic Solid TumorView official trial listing → -
Status unknown NCT NCT04406870
Sirolimus in the Treatment for Infantile Hepatic Hemangioendothelioma(IEEH)
Not yet reported Shanghai Children's Medical Center 36 participants Est. completion 2025-06-30 1 site Stand-aloneOther conditions: Hemangioendothelioma of LiverView official trial listing → -
Active, not recruiting NCT NCT04408625
Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)
Not yet reported, Not yet reported Prevail Therapeutics 35 participants Est. completion 2029-11-30 12 sites Stand-aloneOther conditions: Frontotemporal DementiaView official trial listing → -
Terminated NCT NCT04409327
Phase 2 Study to Determine if RTB101 Reduces the Severity of COVID-19 in Older Adults Residing in Nursing Homes
Not yet reported Restorbio Inc. 36 participants Est. completion 2021-01-24 1 siteOther conditions: COVID19View official trial listing → -
Status unknown NCT NCT04409691
SCMC Trial on KHE With KMP (V.2020)
Not yet reported Shanghai Children's Medical Center 20 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: Kaposiform Hemangioendothelioma (KHE) With Kasabach-Merritt Phenomenon (KMP)View official trial listing → -
Status unknown NCT NCT04409912
Sirolimus Coated Angioplasty Versus Plain Balloon Angioplasty
Not yet reported Singapore General Hospital 170 participants Est. completion 2024-10 3 sites Stand-aloneOther conditions: End Stage Renal Failure on Dialysis, Arteriovenous Graft OcclusionView official trial listing → -
Active, not recruiting NCT NCT04411654
Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)
Not yet reported, Not yet reported Prevail Therapeutics 7 participants Est. completion 2027-02 6 sites Stand-aloneOther conditions: Gaucher Disease, Type 2View official trial listing → -
Withdrawn NCT NCT04415476
Standard Therapy Using Tacrolimus, Mycophenolate Mofetil and Prednisone For Chronic Lung Transplant Rejection (BOS)
Not yet reported University of Maryland, Baltimore Est. completion 2028-06-30 Stand-aloneOther conditions: Disorder Related to Lung Transplantation, Chronic Rejection of Lung Transplant, Decreased Immunologic ActivityView official trial listing → -
Completed NCT NCT04448873
Guided Discontinuation Versus Maintenance Treatment of Sirolimus in Pediatric Patients With Kaposiform Hemangioendothelioma
Not yet reported Children's Hospital of Fudan University 30 participants Est. completion 2023-07-01 1 site Stand-aloneOther conditions: Kaposiform Hemangioendothelioma, Kasabach-Merritt SyndromeView official trial listing → -
Status unknown NCT NCT04461340
Efficacy and Safety of Sirolimus in COVID-19 Infection
Not yet reported Alexandria University 40 participants Est. completion 2020-11-30 1 site Stand-aloneOther conditions: COVID 19View official trial listing → -
Terminated NCT NCT04461886
A Long-term Study of NPC-12G Gel in Neurofibromatosis Type I
Not yet reported Nobelpharma 100 participants Est. completion 2021-12-07 4 sites Stand-aloneOther conditions: NeurofibromatosisView official trial listing → -
Completed NCT NCT04470804
Sirolimus Treatment for Newly Diagnosed Primary Acquired PRCA
Not yet reported Bing Han 56 participants Est. completion 2022-07-31 1 site Stand-aloneOther conditions: Pure Red Cell Aplasia, AcquiredView official trial listing → -
Active, not recruiting NCT NCT04470934
SeQuent® SCB "All Comers" Post Market Clinical Follow-up (PMCF)
B. Braun Melsungen AG 1302 participants Est. completion 2027-03-31 1 siteCardiovascular disease Other conditions: Myocardial IschaemiaView official trial listing → -
Completed NCT NCT04471441
Efficacy and Safety of Everolimus Versus Mycophenolate Mofetil in Liver Transplant Recipients.
Not yet reported Chong Kun Dang Pharmaceutical 150 participants Est. completion 2024-07-24 1 siteOther conditions: Liver TransplantView official trial listing → -
Completed NCT NCT04473911
Haplo Peripheral Blood Sct In GVHD Prevention
Not yet reported Zachariah Michael DeFilipp 25 participants Est. completion 2024-08-19 1 site Stand-aloneOther conditions: GVHD, AML, ALL, MDS, MPN, CMML, Hodgkin Lymphoma, Non Hodgkin Lymphoma, Blood Stem Cell Transplant Failure, Graft Vs Host Disease, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorder, Chronic Myelomonocytic Leukemia, Chemosensitive Hodgkin LymphomaView official trial listing → -
Completed NCT NCT04475536
A Prospective Study, Single-arm, Multicentre, Observational to Evaluate Safety and Effectiveness of Stent Ultimaster Tansei Coronary Stent in Complex Coronary Lesions.
Fundación EPIC 501 participants Est. completion 2024-02-01 17 sitesCardiovascular disease Other conditions: Ischemic Heart DiseaseView official trial listing → -
Active, not recruiting NCT NCT04475783
Sirolimus- vs. Paclitaxel-Drug Coated Ballons in Patients With Peripheral Artery Disease
Not yet reported Jena University Hospital 478 participants Est. completion 2027-12-31 22 sites Stand-aloneOther conditions: Peripheral Artery DiseaseView official trial listing → -
Withdrawn NCT NCT04482712
Effects of mTOR Inhibition With Sirolimus (RAPA) in Patients With COVID-19 to Moderate the Progression of ARDS
Not yet reported, Not yet reported The University of Texas Health Science Center at San Antonio Est. completion 2023-01 2 sitesOther conditions: Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS), Respiratory Failure, Sars-CoV2View official trial listing → -
Completed NCT NCT04488601
Participatory Evaluation (of) Aging (With) Rapamycin (for) Longevity Study
Not yet reported AgelessRx 129 participants Est. completion 2023-12-30 1 siteOther conditions: AgingView official trial listing → -
Status unknown NCT NCT04534257
Prospective Registry to Investigate the Safety and Efficacy of the Treatment With the Selution Sirolimus Drug Coated Balloon in TASC C and D Atheroma-occlusive Infra-Inguinal Disease in Patients With Chronic Limb Threatening Ischemia From Singapore
Not yet reported Singapore General Hospital 75 participants Est. completion 2022-05-20 1 site Stand-aloneOther conditions: Critical Lower Limb Ischemia, Peripheral Artery DiseaseView official trial listing → -
Active, not recruiting NCT NCT04542733
The Efficacy of Everolimus With Reduced-dose Tacrolimus Versus Reduced-dose Tacrolimus and Leflunomide in Treatment of BK Virus Infection in Kidney Transplantation Recipient
Not yet reported King Chulalongkorn Memorial Hospital 50 participants Est. completion 2028-07 1 siteOther conditions: Kidney Transplant Infection, BK Virus InfectionView official trial listing → -
Active, not recruiting NCT NCT04561739
Paclitaxel-coated Balloon for Treatment of De-novo Non-complex Coronary Artery Lesions
Not yet reported Xijing Hospital 2272 participants Est. completion 2027-05-05 1 siteCardiovascular disease Other conditions: De Novo StenosisView official trial listing → -
Active, not recruiting NCT NCT04562532
Firehawk Rapamycin Target Eluting Coronary Stent North American Trial
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 1720 participants Est. completion 2027-06-30 57 sitesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT04562740
ABLUMINUS DES BTK Registry - FIM
Not yet reported Concept Medical Inc. 30 participants Est. completion 2024-12-02 1 site Stand-aloneOther conditions: Peripheral Artery Disease, Arterial Disease of Legs, AtherosclerosisView official trial listing → -
Active, not recruiting NCT NCT04562805
Infinity-Swedeheart Registry Based Randomized Clinical Trial (R-RCT)
Not yet reported Elixir Medical Corporation 2400 participants Est. completion 2028-07-31 19 sites Stand-aloneCardiovascular disease Other conditions: Ischemic Heart DiseaseView official trial listing → -
Status unknown NCT NCT04570345
3 Months Versus 12 Months Dual Antiplatelet Therapy After Drug-eluting Stent Implantation in STEMI
Not yet reported Dong-A University 1002 participants Est. completion 2022-08 1 siteCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT04582136
Efficacy and Safety of Sirolimus in Active Systemic Lupus Erythematosus
Not yet reported Chinese SLE Treatment And Research Group 146 participants Est. completion 2026-01 6 sites Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Active, not recruiting NCT NCT04584710
A Phase 2 Study of RTB101 as COVID-19 Post-Exposure Prophylaxis in Older Adults
Not yet reported Restorbio Inc. 60 participants Est. completion 2021-02 2 sitesOther conditions: Covid19View official trial listing → -
Status unknown NCT NCT04591431
The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy
Not yet reported Fondazione per la Medicina Personalizzata 400 participants Est. completion 2025-06 37 sitesOther conditions: Breast Cancer, Gastrointestinal Cancer, Non Small Cell Lung Cancer, Other CancerView official trial listing → -
Status unknown NCT NCT04594889
Comparison of Sirolimus vs Paclitaxel Drug Eluting Balloon for Below-the-knee Angioplasty in Critical Limb Ischemia
Not yet reported Ospedale San Donato 170 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: Critical Limb Ischemia, Drug EffectView official trial listing → -
Completed NCT NCT04595513
Stopping TSC Onset and Progression 2: Epilepsy Prevention in TSC Infants
Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 5 participants Est. completion 2022-12-15 1 site Stand-aloneOther conditions: Tuberous Sclerosis Complex, EpilepsyView official trial listing → -
Status unknown NCT NCT04598204
Efficacy and Safety of Rapamycin to Complex Vascular Anomalies in Pediatric Patients
Not yet reported, Not yet reported Zhujiang Hospital 30 participants Est. completion 2022-12-01 1 siteOther conditions: Vascular AnomaliesView official trial listing → -
Status unknown NCT NCT04598815
Sirolimus for Graves' Orbitopathy (GO)
Not yet reported University of Pisa 54 participants Est. completion 2025-05-31 1 site Stand-aloneOther conditions: Graves OphthalmopathyView official trial listing → -
Completed NCT NCT04608448
Topical-RAPA Use in Inflammation Reversal and Re-setting the Epigenetic Clock
Not yet reported The University of Texas Health Science Center at San Antonio 22 participants Est. completion 2022-04-15 1 siteOther conditions: Aging, Epigenetics, Inflammatory MediatorsView official trial listing → -
Completed NCT NCT04612179
Post-Market Registry to Evaluate the Safety and Efficacy of the The SUPRAFLEX CRUZ™ Sirolimus Eluting Coronary Stent System in the Treatment of an Octo- and Nonagenerian All-Comer Patient Cohort With Coronary Artery Disease - the Cruz Senior Study
IHF GmbH - Institut für Herzinfarktforschung 2017 participants Est. completion 2025-06-12 1 siteOther conditions: Coronary DiseaseView official trial listing → -
Status unknown NCT NCT04629118
Intervention With Selution SLR™ Agent Balloon for Endovascular Latent Limus Therapy for Failing AV Fistulas (ISABELLA) Trial
Singapore General Hospital 40 participants Est. completion 2023-10-30 1 siteOther conditions: Arteriovenous Fistula, Dialysis Access MalfunctionView official trial listing → -
Active, not recruiting NCT NCT04629495
Rapamycin - Effects on Alzheimer's and Cognitive Health
Not yet reported The University of Texas Health Science Center at San Antonio 40 participants Est. completion 2027-03-05 1 siteOther conditions: Mild Cognitive Impairment, Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT04660240
Randomized Trial Comparing Two Sirolimus-Eluting Stents in Diabetes Mellitus
Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 860 participants Est. completion 2025-09-01 1 site Stand-aloneCardiovascular disease Other conditions: Diabetes Mellitus, Acute Coronary SyndromeView official trial listing → -
Status unknown NCT NCT04661254
Treg Cell Therapy in Liver and Kidney Transplantation - Preclinical Validation of Batches of Treg Cells Amplified in Vitro
Not yet reported Assistance Publique - Hôpitaux de Paris 4 participants Est. completion 2024-04-30 2 sitesOther conditions: Kidney Transplantation, Liver TransplantationView official trial listing → -
Completed NCT NCT04698512
MAgicTouch™ Intervention Leap for Dialysis Access (MATILDA) Trial
Singapore General Hospital 35 participants Est. completion 2021-01-30 1 siteOther conditions: Dialysis Access Malfunction, End Stage Renal Failure on Dialysis, End Stage Renal Disease, Fistulas Arteriovenous, StenosisView official trial listing → -
Status unknown NCT NCT04700709
Efficacy and Safety of Sirolimus Plus CNI Compared With MMF Plus CNI in ABO-i Kidney Transplant Recipients.
Not yet reported Chong Kun Dang Pharmaceutical 158 participants Est. completion 2025-01 1 site Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT04707209
Sirolimus for Retinal Astrocytic Hamartoma
Not yet reported The Hospital for Sick Children 1 participants Est. completion 2024-03-22 1 site Stand-aloneOther conditions: Retinal Astrocytic HamartomaView official trial listing → -
Terminated NCT NCT04720664
Oral SM-88 in Patients With Metastatic HR+/HER2- Breast Cancer
Not yet reported Georgetown University 11 participants Est. completion 2023-02-10 5 sites Stand-aloneOther conditions: Breast Cancer, Metastatic Breast Cancer, Hormone Receptor Positive Breast CarcinomaView official trial listing → -
Not yet recruiting NCT NCT04736589
Inetetamab Plus Rapamycin and Chemotherapy for HER2+ Metastatic Breast Cancer With Abnormal Activation of PAM Pathway
Not yet reported Peking Union Medical College 270 participants Est. completion 2027-02-02 1 siteOther conditions: Breast CancerView official trial listing → -
Not yet recruiting NCT NCT04736953
Sirolimus Treatment Of Patients With SLE
Not yet reported State University of New York - Upstate Medical University 220 participants Est. completion 2029-01-01Other conditions: Lupus Erythematosus, SystemicView official trial listing → -
Active, not recruiting NCT NCT04742777
Effect of mTOR Inhibition & Other Metabolism Modulating Interventions on the Elderly [SubStudy Rapa & cMRI to Evaluate Cardiac Function]
Not yet reported The University of Texas Health Science Center at San Antonio 20 participants Est. completion 2026-10-16 2 sitesOther conditions: AgingView official trial listing → -
Active, not recruiting NCT NCT04772300
Trial to Assess the Safety and Efficacy of Sirolimus-Coated Balloon vs. Uncoated Standard Angioplasty for the Treatment of Below-the-knee Peripheral Arterial Disease
Not yet reported Jena University Hospital 230 participants Est. completion 2028-11-17 19 sites Stand-aloneOther conditions: Peripheral Artery DiseaseView official trial listing → -
Completed NCT NCT04775173
Efficacy and Safety of Different Concentrations of Sirolimus in the Treatment of Kaposiform Hemangioendothelioma.
Not yet reported West China Hospital 79 participants Est. completion 2023-08-10 1 site Stand-aloneOther conditions: Kaposiform HemangioendotheliomaView official trial listing → -
Active, not recruiting NCT NCT04776434
SUCCESS (SelUtion, Safety, effiCaCy, hEalth economicS and promS) PTA Study
Not yet reported M.A. Med Alliance S.A. 723 participants Est. completion 2028-12-31 27 sites Stand-aloneOther conditions: Peripheral Artery DiseaseView official trial listing → -
Active, not recruiting NCT NCT04789070
Phase III Trial of Sirolimus in IBM
Not yet reported University of Kansas Medical Center 140 participants Est. completion 2027-12 10 sitesOther conditions: Inclusion Body MyositisView official trial listing → -
Completed NCT NCT04805619
Evaluation of the Neointimal Healing by OCT of the Tapered DES Biomime Morph (TAPER-I Study)
Not yet reported University of Sao Paulo General Hospital 35 participants Est. completion 2021-12-08 1 site Stand-aloneOther conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT04818632
AZD9833 China PK Study
Not yet reported AstraZeneca 28 participants Est. completion 2023-09-07 4 sitesOther conditions: ER+, HER2-, Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT04849325
IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease
Not yet reported Biotyx Medical (Shenzhen) Co., Ltd. 120 participants Est. completion 2024-10 29 sites Stand-aloneOther conditions: Critical Limb Ischemia (CLI)View official trial listing → -
Status unknown NCT NCT04849533
Belatacept With Early Steroid Withdrawal rATG and Everolimus in Renal Transplantation (BETTER Trial)
Not yet reported University of Cincinnati 120 participants Est. completion 2024-07 2 sitesOther conditions: Kidney Transplant RejectionView official trial listing → -
Completed NCT NCT04862052
Optimal Treatment for Coronary Drug Eluting Stent In-stent Restenosis
Not yet reported Semmelweis University Heart and Vascular Center 108 participants Est. completion 2025-01-30 2 sites Stand-aloneOther conditions: Coronary Stent RestenosisView official trial listing → -
Status unknown NCT NCT04867720
Efficacy and Safety of CertiroBell® Tablet Plus Tacrolimus in Primary Living Donor Liver Transplant Recipients
Not yet reported Chong Kun Dang Pharmaceutical 112 participants Est. completion 2023-02-22 1 siteOther conditions: Liver TransplantView official trial listing → -
Terminated NCT NCT04885816
Drug-eluting Balloon Versus Drug-eluting Stent for High Bleeding Risk Angioplasty
Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 5 participants Est. completion 2021-09-29 1 siteCardiovascular disease Other conditions: High Bleeding Risk, Percutaneous Coronary Intervention (PCI)View official trial listing → -
Status unknown NCT NCT04892212
Sirolimus in Treatment of Proteinuric Flares of Lupus Nephritis
Not yet reported, Not yet reported Peking Union Medical College Hospital 20 participants Est. completion 2023-10-30 Stand-aloneOther conditions: Lupus Nephritis, Immunosuppression, Effect of DrugView official trial listing → -
Active, not recruiting NCT NCT04893291
Sirolimus-coated Balloon Versus Drug-eluting Stent in Native Coronary Vessels - TRANSFORM II
Not yet reported Fondazione Ricerca e Innovazione Cardiovascolare ETS 1820 participants Est. completion 2030-08-30 53 sites Stand-aloneCardiovascular disease Other conditions: Coronary Artery StenosisView official trial listing → -
Completed NCT NCT04893486
CODY: A Study Evaluating The Safety And Efficacy Of QTORIN 3.9% Sirolimus Topical Gel For The Prevention Of Basal Cell Carcinomas (BCCs) In Patients With Gorlin Syndrome
Not yet reported Palvella Therapeutics, Inc. 73 participants Est. completion 2023-03-13 16 sites Stand-aloneOther conditions: BCCs in Gorlin Syndrome PatientsView official trial listing → -
Terminated NCT NCT04895748
DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies
Not yet reported Novartis Pharmaceuticals 40 participants Est. completion 2026-02-13 11 sitesOther conditions: Carcinoma, Renal CellView official trial listing → -
Status unknown NCT NCT04896177
Sirolimus DEB in Coronary Bifurcation Lesions
Not yet reported Shenzhen Salubris Pharmaceuticals Co., Ltd. 280 participants Est. completion 2026-09-18 1 site Stand-aloneOther conditions: Coronary Bifurcation LesionsView official trial listing → -
Active, not recruiting NCT NCT04899141
Prospective Registry of ihtDEStiny® Coronary Stent in Regular PCI Practice
Fundación EPIC 400 participants Est. completion 2028-05-01 20 sitesCardiovascular disease Other conditions: Ischemic Heart DiseaseView official trial listing → -
Status unknown NCT NCT04899583
ACOART SCB BIF: Treatment of Coronary Bifurcation Lesion by Sirolimus Coated Balloon vs Paclitaxel Coated Balloon
Not yet reported Acotec Scientific Co., Ltd 230 participants Est. completion 2025-11-01 1 site Stand-aloneOther conditions: Coronary Bifurcation LesionsView official trial listing → -
Completed NCT NCT04906304
Comparison of Safety and Efficacy of de Novo Everolimus
Not yet reported Shahid Beheshti University of Medical Sciences 35 participants Est. completion 2020-08-01 1 siteOther conditions: Cytomegalovirus InfectionsView official trial listing → -
Status unknown NCT NCT04918615
Compare Sirolimus Coated Balloon Catheter With Paclitaxel Coated Balloon Catheter in De Novo Coronary Bifurcated Lesions
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 236 participants Est. completion 2024-12-31 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT04919226
Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE
Not yet reported ITM Solucin GmbH 259 participants Est. completion 2027-09 42 sitesOther conditions: Neuroendocrine TumorsView official trial listing → -
Status unknown NCT NCT04921722
Percutaneous Administration of Sirolimus in the Treatment of Superficial Complicated Vascular Anomalies
Not yet reported Children's Hospital of Fudan University 75 participants Est. completion 2025-11-01 1 site Stand-aloneOther conditions: Kaposiform Hemangioendothelioma, Tufted Angioma, Superficial Vascular Anomalies, Superficial Lymphatic MalformationsView official trial listing → -
Withdrawn NCT NCT04936971
Introduction of mTor Inhibitors and the Activation of the Cytomegalovirus (CMV) -Specific Cellular Immune Response
Not yet reported Edoardo Melilli Est. completion 2021-09 1 siteOther conditions: Kidney Transplantation, Cytomegalovirus InfectionsView official trial listing → -
Active, not recruiting NCT NCT04948203
Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis
Not yet reported, Not yet reported University of Chicago 60 participants Est. completion 2026-12 1 siteOther conditions: Pulmonary Fibrosis, COVID-19 Pneumonia, Long COVIDView official trial listing → -
Status unknown NCT NCT04949880
A Single-Arm Trial of Neurovascular Drug-Eluting Balloon Dilatation Catheter Treating Symptomatic Intracranial Atherosclerotic Stenosis
Not yet reported Zhejiang Zylox Medical Device Co., Ltd. 132 participants Est. completion 2023-05 11 sites Stand-aloneOther conditions: Intracranial AtherosclerosisView official trial listing → -
Active, not recruiting NCT NCT04951050
TARGET-PREMIER Trail in Evaluating the Safety and Efficacy of the Rapamycin Target Eluting Stent in CAS Treatment
Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 200 participants Est. completion 2027-12-31 1 siteCardiovascular disease Other conditions: Coronary StenosisView official trial listing → -
Terminated NCT NCT04965688
Biology Guided Therapy for Breast Cancer for ER Positive
Not yet reported Inova Health Care Services 2 participants Est. completion 2024-03-13 1 siteOther conditions: Breast Cancer, Estrogen Receptor-positive Breast Cancer, HER2-negative Breast CancerView official trial listing → -
Status unknown NCT NCT04982367
Acoart SCB SFA: Sirolimus Coated Balloon Catheter in the Treatment of Femoropopliteal Artery Stenosis
Not yet reported Acotec Scientific Co., Ltd 166 participants Est. completion 2024-07 1 site Stand-aloneOther conditions: Peripheral Artery DiseaseView official trial listing → -
Status unknown NCT NCT04987463
Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants
Not yet reported, Not yet reported Katarzyna Kotulska 60 participants Est. completion 2026-03 2 sitesOther conditions: Tuberous Sclerosis ComplexView official trial listing → -
Completed NCT NCT04989686
Microsampling Assays for Immunosuppressive Drugs in Children
Children's Hospital of Philadelphia 66 participants Est. completion 2025-05-01 1 siteOther conditions: ImmunosuppressionView official trial listing → -
Status unknown NCT NCT04993872
Pharmacokinetics of Calcineurin & mTOR Inhibitors in HIV-1 Infected Kidney Transplant Recipients After Switch to BIC/FTC/TAF
Not yet reported Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba 5 participants Est. completion 2024-07-01 2 sitesOther conditions: HIV-infected Patient Kidney Transplant RecipientView official trial listing → -
Withdrawn NCT NCT04994561
VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements
Not yet reported Vitality in Aging Research Group, Inc. Est. completion 2023-12Other conditions: AgingView official trial listing → -
Not yet recruiting NCT NCT04995159
Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVas™ BRS System
Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 2150 participants Est. completion 2028-01 114 sitesOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT04996719
Effect of Rapamycin to Improve Cardiac Function in Frail Older Adults
Not yet reported Mayo Clinic 24 participants Est. completion 2023-08-25 1 siteHeart failureView official trial listing → -
Active, not recruiting NCT NCT05012371
Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer
Not yet reported M.D. Anderson Cancer Center 90 participants Est. completion 2027-10-25 3 sitesOther conditions: Advanced Clear Cell Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8View official trial listing → -
Status unknown NCT NCT05032131
Cell Therapy for IBM by Muscle Injection of ADSVF
Not yet reported Assistance Publique - Hôpitaux de Paris 32 participants Est. completion 2024-04 1 site Stand-aloneOther conditions: Inclusion Body MyositisView official trial listing → -
Status unknown NCT NCT05033964
The DESyne BDS Plus RCT: A Randomized Clinical Trial to Assess the Elixir DESyne BDS Plus Drug Eluting Coronary Stent System for the Treatment of de Novo Native Coronary Artery Lesions
Not yet reported Elixir Medical Corporation 200 participants Est. completion 2026-03 14 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT05050149
Study Evaluating the Safety and Efficacy of PTX-022 (QTORIN Sirolimus) in the Treatment of Microcystic Lymphatic Malformations
Not yet reported Palvella Therapeutics, Inc. 12 participants Est. completion 2022-12-15 7 sitesOther conditions: Microcystic Lymphatic MalformationView official trial listing → -
Terminated NCT NCT05065411
Efficacy & Safety Evaluation of Enobosarm in Combo With Abemaciclib in Treatment of ER+HER2- Metastatic Breast Cancer
Not yet reported Veru Inc. 5 participants Est. completion 2024-01-09 30 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Terminated NCT NCT05066789
CHoice of Optimal Anti-Thrombotic Strategy in Patients Undergoing Implantation of Coronary Drug-Eluting Stents 4
Not yet reported Samsung Medical Center 100 participants Est. completion 2024-03-22 1 siteCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT05079360
Efficacy Evaluation of Sabizabulin Monotherapy Versus Active Control for Treatment of ER+HER2- Metastatic Breast Cancer
Not yet reported Veru Inc. Est. completion 2024-05-26 26 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Active, not recruiting NCT NCT05088356
Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft
Not yet reported Stanford University 66 participants Est. completion 2028-05 1 site Stand-aloneOther conditions: Allogeneic Hematopoietic Cell Transplantation (HCT), Advanced Hematologic Malignancies, Acute Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndromes, Myeloproliferative DisordersView official trial listing → -
Status unknown NCT NCT05101005
Long-term Efficacy of Drug-coated Balloon Versus Drug-eluting Stent in Large de Novo Coronary Lesions
Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 400 participants Est. completion 2023-11Cardiovascular disease Other conditions: Drug-coated BalloonView official trial listing → -
Completed NCT NCT05103358
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)
Not yet reported Aadi Bioscience, Inc. 128 participants Est. completion 2024-12-23 166 sites Stand-aloneOther conditions: Tumor, Tumor, Solid, Metastasis, Metastatic Cancer, Cancer, Cancer Metastatic, Tumors, Neoplasms, Neoplasm Metastasis, Solid Tumor, Advanced Solid Tumor, Advanced Cancer, Malignant Solid Tumor, Malignant Solid Neoplasm, Malignant Neoplasm, Malignant Tumor, TSC, TSC1, TSC2, Metastatic Solid Tumor, Metastatic NeoplasmView official trial listing → -
No Longer Available NCT NCT05108740
MAP Treatment Plan With Afinitor for Postmenopausal Women With Advanced HR+ Breast Cancer
Novartis PharmaceuticalsOther conditions: Advanced Hormone Receptor Positive (HR+) Breast CancerView official trial listing → -
Completed NCT NCT05120570
PTCy + Sirolimus/VIC-1911 as GVHD Prophylaxis in Myeloablative PBSC Transplantation
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 16 participants Est. completion 2025-06-30 1 site Stand-aloneOther conditions: Acute Leukemia, Myelodysplastic Syndromes, Myeloproliferative Neoplasm, LymphomaView official trial listing → -
Status unknown NCT NCT05124431
Anlotinib Plus Everolimus as First-line Treatment for Advanced Non Clear Cell Renal Cell Carcinoma
Not yet reported Fudan University 30 participants Est. completion 2024-12 1 siteOther conditions: Renal Cell CarcinomaView official trial listing → -
Status unknown NCT NCT05125523
A Study of Sirolimus for Injection (Albumin Bound) in Patients With Advanced Solid Tumors
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 264 participants Est. completion 2024-11 1 site Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Active, not recruiting NCT NCT05132166
A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to the Best Available Treatment in Graft Versus Host Disease
Not yet reported University Health Network, Toronto 50 participants Est. completion 2026-04-26 1 siteOther conditions: Graft Vs Host DiseaseView official trial listing → -
Active, not recruiting NCT NCT05132361
SELUTION4SFA Trial
Not yet reported M.A. Med Alliance S.A. 300 participants Est. completion 2030-12-01 38 sites Stand-aloneOther conditions: Peripheral Arterial Disease, Superficial Femoral Artery StenosisView official trial listing → -
Available NCT NCT05134922
Expanded Access Protocol for Subjects Previously Treated With Gedatolisib in B2151009
Celcuity Inc 5 sitesOther conditions: Breast Neoplasm Malignant FemaleView official trial listing → -
Completed NCT NCT05153668
Everolimus Trial in Laryngotracheal Stenosis
Not yet reported Johns Hopkins University 8 participants Est. completion 2025-10-23 1 siteOther conditions: Idiopathic Subglottic Tracheal StenosisView official trial listing → -
Withdrawn NCT NCT05170828
Cryopreserved MMUD BM With PTCy for Hematologic Malignancies
Not yet reported Ossium Health, Inc. Est. completion 2024-11Other conditions: Acute Leukemia, Myelodysplastic Syndromes, T-lymphoblastic Lymphoma, Acute Lymphocytic Leukemia, Acute Myeloid Leukemia, Acute Biphenotypic Leukemia, Acute Undifferentiated LeukemiaView official trial listing → -
Completed NCT NCT05180708
A Multicenter, Phase 3 Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Pachyonychia Congenita
Not yet reported Palvella Therapeutics, Inc. 87 participants Est. completion 2023-06-30 8 sitesOther conditions: Pachyonychia CongenitaView official trial listing → -
Completed NCT NCT05188118
Rapid Sequencing of Approved Therapies in Patients With Metastatic or Unresectable Clear Cell Renal Cell Carcinoma
Not yet reported Icahn School of Medicine at Mount Sinai 10 participants Est. completion 2026-06-05 1 siteOther conditions: Renal Cell CarcinomaView official trial listing → -
Status unknown NCT NCT05190627
Effect of Loratadine in Lymphangioleiomyomatosis
Not yet reported Institut d'Investigació Biomèdica de Bellvitge 62 participants Est. completion 2023-12-30 6 sitesOther conditions: LymphangioleiomyomatosisView official trial listing → -
Active, not recruiting NCT NCT05193565
Study to Compare the Efficacy and Safety After Conversion to RaparoBell® or My-Rept® in Kidney Transplant Patients
Not yet reported Chong Kun Dang Pharmaceutical 206 participants Est. completion 2026-11 1 site Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Completed NCT NCT05198427
mTOR Inhibitors: the Lesions Induced by Papillomavirus for Transplant Patients.
Hospices Civils de Lyon 45 participants Est. completion 2022-03-31 1 siteOther conditions: Transplantation OrganView official trial listing → -
Active, not recruiting NCT NCT05205499
A Clinical Trial to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease
Not yet reported Biotyx Medical (Shenzhen) Co., Ltd. 1059 participants Est. completion 2028-08 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT05206084
A Clinical Investigation to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease
Not yet reported Biotyx Medical (Shenzhen) Co., Ltd. 518 participants Est. completion 2028-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT05240781
Zotarolimus vs Sirolimus Eluting Stent in High Bleeding Risk
Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 280 participants Est. completion 2025-02-28 1 site Stand-aloneCardiovascular disease Other conditions: High Bleeding Risk, Percutaneous Coronary InterventionView official trial listing → -
Active, not recruiting NCT NCT05252585
A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)
Not yet reported Novartis Pharmaceuticals 4 participants Est. completion 2026-10-10 4 sitesOther conditions: Renal AngiomyolipomaView official trial listing → -
Status unknown NCT NCT05267548
Investigating the Safety and Clinical Performance of Seven iVascular Devices for Endovascular Intervention in the Popliteal and/or Infrapopliteal Arteries
iVascular S.L.U. 143 participants Est. completion 2025-05 8 sitesOther conditions: Peripheral Arterial Disease Below The KneeView official trial listing → -
Completed NCT NCT05269849
Sirolimus for Nosebleeds in HHT
Not yet reported Unity Health Toronto 10 participants Est. completion 2024-12-02 1 site Stand-aloneOther conditions: Hereditary Hemorrhagic Telangiectasia, Nosebleeds, EpistaxisView official trial listing → -
Completed NCT NCT05274308
Stability of Tacrolimus, Cyclosporine A, Everolimus and Sirolimus in Whole Blood Patient Samples
Thermo Fisher Scientific Oy 46 participants Est. completion 2022-07-26 1 siteOther conditions: Transplantation Drugs StabilityView official trial listing → -
Active, not recruiting NCT NCT05293964
Phase I Study to Evaluate SIM0270 Alone or in Combination in ER+, HER2- Locally Advanced or Metastatic Breast Cancer
Not yet reported Jiangsu Simcere Pharmaceutical Co., Ltd. 214 participants Est. completion 2025-09-08 1 siteOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT05294822
Autologous Regenerative Islet Transplantation for Insulin-dependent Diabetes
Not yet reported Shanghai Changzheng Hospital 20 participants Est. completion 2023-12 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Terminated NCT NCT05298358
RIC alloBMT With Post-transplant Cyclophosphamide for Refractory Systemic Sclerosis
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 1 participants Est. completion 2024-11-21 1 site Stand-aloneOther conditions: Systemic SclerosisView official trial listing → -
Active, not recruiting NCT NCT05306340
A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)
Not yet reported Genentech, Inc. 373 participants Est. completion 2026-10-15 136 sitesOther conditions: Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT05324384
Different Doses of Sirolimus for the Maintenance Treatment of Kaposiform Hemangioendothelioma
Not yet reported West China Hospital 30 participants Est. completion 2025-11-30 1 site Stand-aloneOther conditions: HemangioendotheliomaView official trial listing → -
Status unknown NCT NCT05333640
A Real-world Registry Investigating Sirolimus-coated Balloon Versus Paclitaxel-coated Balloon Angioplasty for the Treatment of Dysfunctional Arteriovenous Fistula
Singapore General Hospital 200 participants Est. completion 2024-04-30 1 siteOther conditions: Dialysis Access Malfunction, StenosisView official trial listing → -
Active, not recruiting NCT NCT05342519
Daily Topical Rapamycin for Vitiligo
Not yet reported Medical University of South Carolina 20 participants Est. completion 2027-12-01 1 siteOther conditions: VitiligoView official trial listing → -
Active, not recruiting NCT NCT05357482
Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia
Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 40 participants Est. completion 2027-01-31 1 site Stand-aloneOther conditions: Sickle Cell Anemia, Beta ThalassemiaView official trial listing → -
Status unknown NCT NCT05362994
Selution Sirolimus-eluting Balloon for Internal Pudendal-penile Artery Disease-related Erectile Dysfunction
Not yet reported National Taiwan University Hospital 54 participants Est. completion 2025-02-28 1 site Stand-aloneOther conditions: Erectile Dysfunction, Peripheral Arterial Disease, Arterial StenosisView official trial listing → -
Active, not recruiting NCT NCT05384756
TMLI and Alemtuzumab for Treatment of Sickle Cell Disease
Not yet reported City of Hope Medical Center 20 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Active, not recruiting NCT NCT05386914
This Study Consists of Two Study Parts Conducted Under a Single IRB. Part I: Short Term ApoE-dependent Cerebral Blood Flow Response to Sirolimus in Cognitively Normal Adults Part II: Short Term ApoE-dependent Cerebral Blood Flow and Lung Perfusion Response to Sirolimus in Cognitively Normal Adults
Not yet reported University of Missouri-Columbia 205 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Genetic Predisposition to Disease, Healthy VolunteersView official trial listing → -
Active, not recruiting NCT NCT05406622
MOTIV BTK Randomized Controlled Trial
Not yet reported REVA Medical, Inc. 292 participants Est. completion 2030-03-31 26 sites Stand-aloneOther conditions: Critical Limb IschemiaView official trial listing → -
Withdrawn NCT NCT05417893
Non-inferiority Clinical Trial to Compare the Safety and Performance of MeRes100 Sirolimus-eluting BioResorbable Vascular Scaffold System Versus Contemporary DES Platforms in Patients With de Novo Coronary Artery Lesions
Not yet reported Meril Life Sciences Pvt. Ltd. Est. completion 2023-09-23Cardiovascular diseaseView official trial listing → -
Completed NCT NCT05425056
A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery
Not yet reported Vascular Therapies, Inc. 136 participants Est. completion 2025-08-29 22 sites Stand-aloneOther conditions: Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD, Chronic Kidney Failure, Complication of Hemodialysis, Vascular Access Complication, Arteriovenous FistulaView official trial listing → -
Status unknown NCT NCT05429684
Precise Therapy for Refractory HER2 Positive Advanced Breast Cancer
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 120 participants Est. completion 2024-02-28 2 sitesOther conditions: HER2+ Breast CancerView official trial listing → -
Completed NCT NCT05448625
Genoss DES in Patients With a High Risk of Ischemic Events (GENTLE Registry)
Yonsei University 200 participants Est. completion 2025-09-23 1 siteCardiovascular disease Other conditions: Drug-eluting StentView official trial listing → -
Not yet recruiting NCT NCT05458492
Sirolimus in Cutaneous Sarcoidosis
Not yet reported Assistance Publique - Hôpitaux de Paris 10 participants Est. completion 2027-05 Stand-aloneOther conditions: Sarcoidosis, Cutaneous SarcoidosisView official trial listing → -
Active, not recruiting NCT NCT05467397
Feasibility of [11C]Acetate-PET in LAM and TSC
Not yet reported, Not yet reported Brigham and Women's Hospital 7 participants Est. completion 2026-06-30 1 siteOther conditions: Lymphangioleiomyomatosis, Tuberous Sclerosis ComplexView official trial listing → -
Completed NCT NCT05471245
AnGiographic Performance With A Sirolimus-elutiNG Balloon in the TrEatment of De Novo CoronaRy Artery Disease
Not yet reported Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS 110 participants Est. completion 2025-10-08 7 sitesOther conditions: Coronary RestenosisView official trial listing → -
Completed NCT NCT05490095
Randomized Crossover of SVG101(Dispersible Tab. of Everolimus) and Afinitor 5mg in Healthy Adults
Not yet reported Sovargen 26 participants Est. completion 2022-02-07 1 siteOther conditions: PharmacokineticsView official trial listing → -
Completed NCT NCT05495425
Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSC
Not yet reported Nobelpharma 43 participants Est. completion 2024-10-30 5 sites Stand-aloneOther conditions: Tuberous Sclerosis ComplexView official trial listing → -
Completed NCT NCT05501769
ARV-471 in Combination With Everolimus for the Treatment of Advanced or Metastatic ER+, HER2- Breast Cancer
Not yet reported Arvinas Estrogen Receptor, Inc. 32 participants Est. completion 2025-08-25 9 sitesOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT05508620
A Study of Sirolimus for Injection (Albumin-bound) in Patients With Advanced Solid Tumors
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 270 participants Est. completion 2024-12 Stand-aloneOther conditions: Malignant Solid TumorsView official trial listing → -
Active, not recruiting NCT NCT05508906
Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer
Not yet reported Olema Pharmaceuticals, Inc. 190 participants Est. completion 2028-01-31 16 sitesOther conditions: Metastatic Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, Breast Cancer, Locally Advanced Breast CancerView official trial listing → -
Active, not recruiting NCT NCT05522231
Efficacy and Safety of Fruquintinib in Combination With Sintilimab in Advanced Renal Cell Carcinoma (FRUSICA-2)
Not yet reported, Not yet reported Hutchmed 265 participants Est. completion 2025-03 48 sitesOther conditions: Advanced Renal Cell CarcinomaView official trial listing → -
Status unknown NCT NCT05532072
Rapamycin Plus Methylprednisolone Versus Methylprednisolone Alone in Active, Moderate-to-severe Graves' Orbitopathy.
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 140 participants Est. completion 2023-09 1 siteOther conditions: Graves OphthalmopathyView official trial listing → -
Active, not recruiting NCT NCT05540223
Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold System
Not yet reported Biotronik AG 1861 participants Est. completion 2032-02 1 site Stand-aloneCardiovascular disease Other conditions: Atherosclerosis, Coronary, Myocardial Ischemia, Ischemic Heart Disease, Acute Coronary Syndrome, Angina PectorisView official trial listing → -
Status unknown NCT NCT05548023
Time-trend Analysis of Clinical Characteristic and Outcomes in Patients With Unprotected Left Main Coronary Artery Disease Treated With PCI Over a 10-year Period
Not yet reported Chinese University of Hong Kong 500 participants Est. completion 2025-02-07 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT05556681
Study of BD Sirolimus Drug Coated Catheter for Treatment of Femoropopliteal Arteries
Not yet reported C. R. Bard 34 participants Est. completion 2025-11-24 10 sites Stand-aloneOther conditions: Peripheral Arterial Disease, Peripheral Artery Disease, Stenosis ArteryView official trial listing → -
Terminated NCT NCT05557292
RMC-5552 Monotherapy in Adult Subjects With Recurrent Glioblastoma
Not yet reported Nicholas Butowski 7 participants Est. completion 2025-12-31 1 siteOther conditions: Glioblastoma, Recurrent GlioblastomaView official trial listing → -
Active, not recruiting NCT NCT05563220
Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer
Not yet reported, Not yet reported Stemline Therapeutics, Inc. 435 participants Est. completion 2028-12-28 83 sitesOther conditions: Breast Cancer, Metastatic Breast CancerView official trial listing → -
Terminated NCT NCT05571670
Bile Acids in Acute Insulin Resistance
Columbia University 3 participants Est. completion 2022-06-10 1 siteOther conditions: PI3K Gene Mutation, AKT Gene Mutation, MTOR Gene Mutation, Cancer, Insulin ResistanceView official trial listing → -
Completed NCT NCT05605665
Low-dose Interleukin-2 and Rapamycin on sjögren's Syndrome
Not yet reported, Not yet reported Peking University People's Hospital 30 participants Est. completion 2024-03-31 1 siteOther conditions: Sjögren's SyndromeView official trial listing → -
Active, not recruiting NCT NCT05613010
Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver Transplant
Not yet reported Johns Hopkins University 65 participants Est. completion 2027-08-30 1 site Stand-aloneOther conditions: Transplant;Failure,Kidney, Transplant; Failure, Liver, Adherence, Medication, Adherence, Patient, Adherence, TreatmentView official trial listing → -
Status unknown NCT NCT05613166
Adjunctive Everolimus Treatment of Refractory Epilepsy
Not yet reported National Institute on Drug Dependence, China 108 participants Est. completion 2023-03 1 siteOther conditions: EpilepsyView official trial listing → -
Status unknown NCT NCT05616156
The Cre8™ BTK Post Market Clinical Follow-up Study
CID S.p.A. 50 participants Est. completion 2023-07 2 sitesOther conditions: Peripheral Arterial DiseaseView official trial listing → -
Status unknown NCT NCT05625919
A Study of Safety and Efficacy of Sirolimus for Injection (Albumin-bound) in Patients With Advanced Malignant Perivascular Epithelioid Cell Tumor (PEComa)
Not yet reported, Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 54 participants Est. completion 2024-11 1 site Stand-aloneOther conditions: Advanced Malignant Perivascular Epithelioid Cell Tumor (PEComa)View official trial listing → -
Status unknown NCT NCT05662618
To Verify the Efficacy and Safety of Rapamycin Coated Peripheral Balloon Catheter in the Treatment of Femoral Popliteal Artery Disease
Not yet reported Shanghai Bomaian Medical Technology Co., Ltd 276 participants Est. completion 2025-06-30 1 siteOther conditions: Peripheral Arterial DiseaseView official trial listing → -
Completed NCT NCT05663944
REpurposing SirolimUS in Compensated Advanced Chronic Liver Disease. the RESUS Proof of Concept Study
Not yet reported Nottingham University Hospitals NHS Trust 41 participants Est. completion 2024-06-25 1 site Stand-aloneOther conditions: Advanced Chronic Liver DiseaseView official trial listing → -
Terminated NCT NCT05667285
BIOFLOW-china Post-marketing Study (BIOTRONIK)
Biotronik (Beijing) Medical Device Ltd. 122 participants Est. completion 2024-09-27 2 sitesOther conditions: In-Stent Stenosis (Restenosis) of Coronary Artery Stent, Native Coronary Artery StenosisView official trial listing → -
Completed NCT NCT05677711
Safety and Efficacy of the Ultimaster Stent
Yonsei University 204 participants Est. completion 2025-01-03 1 siteCardiovascular disease Other conditions: Drug-eluting StentsView official trial listing → -
Status unknown NCT NCT05703646
Safety and Clinical Performance of the Yukon Choice PC, Yukon Chrome PC & Yukon Choice Flex Stents in Routine Practice
Translumina GmbH 5000 participants Est. completion 2026-03-30 1 siteOther conditions: Ischemic Heart DiseaseView official trial listing → -
Active, not recruiting NCT NCT05705973
Ultimaster Nagomi™ Sirolimus Eluting Coronary Stent System in Complex PCI Patients
Terumo Europe N.V. 3000 participants Est. completion 2027-04-29 52 sitesCardiovascular disease Other conditions: Coronary Artery Occlusion, Ischemic Heart DiseaseView official trial listing → -
Completed NCT NCT05719883
Evaluating the Safety and Efficacy of the Maurora® DES in ICAS
Not yet reported Beijing Tiantan Hospital 156 participants Est. completion 2025-05-15 1 site Stand-aloneCardiovascular disease Other conditions: Intracranial ArteriosclerosisView official trial listing → -
Not yet recruiting NCT NCT05746689
Study of Sirolimus in IgG4-related Disease
Not yet reported Peking University International Hospital 20 participants Est. completion 2028-12-31 Stand-aloneOther conditions: IgG4-related DiseaseView official trial listing → -
Terminated NCT NCT05773326
Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG
Not yet reported Nader Sanai 5 participants Est. completion 2025-10-16 1 siteOther conditions: High Grade Glioma, Glioma, Glioma, Malignant, GlioblastomaView official trial listing → -
Status unknown NCT NCT05780359
Evaluating the Safety and Efficacy of the G-stream® Drug-Eluting Stent in the Above-the-Knee Femoropopliteal Artery
Not yet reported Shenzhen Salubris Pharmaceuticals Co., Ltd. 280 participants Est. completion 2026-08-31 1 site Stand-aloneOther conditions: Peripheral Artery DiseaseView official trial listing → -
Status unknown NCT NCT05801003
Cutting Balloon Predilation Prior to Abluminus Sirolimus-eluting Stent Implantation (CUT-DRESS).
Not yet reported Hospital Universitario La Fe 96 participants Est. completion 2025-01-01 3 sitesCardiovascular disease Other conditions: Percutaneous Coronary Intervention, Cutting BalloonView official trial listing → -
Active, not recruiting NCT NCT05810870
PIK3CA/PTEN-altered Advanced Breast Cancer Treated With MEN1611 Monotherapy or in Combination With Eribulin
Not yet reported MedSIR 14 participants Est. completion 2027-07 13 sitesOther conditions: Breast Cancer, Advanced Breast Cancer, Metastatic Breast CancerView official trial listing → -
Active, not recruiting NCT NCT05826964
Levels of Circulating Tumor DNA as a Predictive Marker for Early Switch in Treatment for Patients With Metastatic (Stage IV) Breast Cancer
Not yet reported University of Miami 24 participants Est. completion 2029-07-31 1 siteOther conditions: Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT05833815
Addition of Everolimus to Standard of Care in Carcinoma Gallbladder
Not yet reported, Not yet reported Banaras Hindu University 56 participants Est. completion 2024-12-30 1 siteOther conditions: Gallbladder CancerView official trial listing → -
Completed NCT NCT05835999
Everolimus Aging Study
Not yet reported University of Wisconsin, Madison 106 participants Est. completion 2026-07-22 1 siteOther conditions: Aging, Insulin ResistanceView official trial listing → -
Active, not recruiting NCT NCT05836025
Effect of Rapamycin in Ovarian Aging
Not yet reported Columbia University 50 participants Est. completion 2026-09 1 siteOther conditions: PerimenopausalView official trial listing → -
Terminated NCT NCT05840510
Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19)
Not yet reported Mirati Therapeutics Inc. 6 participants Est. completion 2024-12-27 3 sites Stand-aloneOther conditions: Solid Tumor, Adult, NSCLC, Advanced Cancer, Metastatic Cancer, Malignant Neoplastic DiseaseView official trial listing → -
Active, not recruiting NCT NCT05860881
Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin)
Not yet reported Melanoma and Skin Cancer Trials Limited 146 participants Est. completion 2027-09-30 6 sites Stand-aloneOther conditions: Solid Organ Transplant Recipients, Skin CancerView official trial listing → -
Completed NCT NCT05915468
Large De-NOVo Coronary artEry Disease Treated With Sirolimus Drug Eluting Balloon (LOVE DEB)
Wrightington, Wigan and Leigh NHS Foundation Trust 306 participants Est. completion 2025-12-11 1 siteCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT05920512
Combination Regimen With Sodium Valproate for Severe Hemophilia: a Single-arm, Phase 1, Pilot Trial.
Not yet reported, Not yet reported Xue-chun Lu 10 participants Est. completion 2025-04-01 1 site Stand-aloneOther conditions: HemophiliaView official trial listing → -
Status unknown NCT NCT05938530
Sirolimus Drug-coated Balloon Versus Stent Graft
Not yet reported Singapore General Hospital 100 participants Est. completion 2026-08 1 site Stand-aloneOther conditions: Arteriovenous Shunt Thrombosis, Blood Vessel ProsthesisView official trial listing → -
Active, not recruiting NCT NCT05946629
SELUTION 4 De Novo Small Vessel IDE Trial
Not yet reported M.A. Med Alliance S.A. 960 participants Est. completion 2031-09 70 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT05952206
Ischemic and Bleeding Outcomes After Angiolite Stent Implantation and an Abbreviated Dual Antiplatelet Therapy
Not yet reported iVascular S.L.U. 2312 participants Est. completion 2030-01-13 38 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT05954442
Everolimus With Investigator's Choice of Chemotherapy in Advanced Triple-Negative Breast Cancer (TNBC) With Luminal Androgen Receptor (LAR) Subtype
Not yet reported Fudan University 203 participants Est. completion 2026-08 1 siteOther conditions: Triple Negative Breast Cancer, Metastatic Breast Cancer, MutationView official trial listing → -
Status unknown NCT NCT05963620
Long-term Follow-up of a Randomized Comparison of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Surgery
Heart Center Leipzig - University Hospital 201 participants Est. completion 2024-02 4 sitesCardiovascular disease Other conditions: Coronary StenosisView official trial listing → -
Status unknown NCT NCT05971394
IBS Titan™ Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System Clinical Trial
Not yet reported Biotyx Medical (Shenzhen) Co., Ltd. 100 participants Est. completion 2026-07 1 site Stand-aloneOther conditions: Infrapopliteal Lesions, Critical Limb IschemiaView official trial listing → -
Completed NCT NCT05997056
Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors
Not yet reported Aadi Bioscience, Inc. 12 participants Est. completion 2025-10-03 4 sites Stand-aloneOther conditions: Neuroendocrine Tumors, NET, Pancreatic Neuroendocrine Tumor, Gastrointestinal Neuroendocrine Tumor, Pulmonary Neuroendocrine TumorView official trial listing → -
Completed NCT NCT06013007
Joint Inflation With Nominal-pressure and Stability Approach in DES Optimization
Not yet reported Zunyi Medical College 161 participants Est. completion 2026-03-05 1 site Stand-aloneOther conditions: Acute Coronary Syndrome, De Novo StenosisView official trial listing → -
Completed NCT NCT06022068
Evaluating Rapamycin Treatment in Alzheimer's Disease Using Positron Emission Tomography
Not yet reported, Not yet reported Karolinska Institutet 14 participants Est. completion 2025-01-17 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Withdrawn NCT NCT06056193
The SIR-POBA Bypass Trial
Not yet reported Paracelsus Medical University Est. completion 2027-10-01 1 siteAlcohol use disorder Other conditions: Peripheral Arterial Occlusive Disease, Bypass Complication, Femoropopliteal Artery Occlusion, Femoropopliteal Stenosis, Critical Limb-Threatening IschemiaView official trial listing → -
Withdrawn NCT NCT06056206
The SIR-POBA Shunt Trial
Not yet reported Paracelsus Medical University Est. completion 2027-10-01 1 siteOther conditions: Arteriovenous Fistula StenosisView official trial listing → -
Completed NCT NCT06065345
BRight Pharmacokinetic Study
Not yet reported Biotronik CRC Inc. 6 participants Est. completion 2025-07-22 1 siteOther conditions: Peripheral Artery DiseaseView official trial listing → -
Completed NCT NCT06066476
Efficacy and Safety of GENOSS® DES in Patients with Coronary Artery Disease
Genoss Co., Ltd. 1022 participants Est. completion 2024-10-31 1 siteCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT06075368
Efficacy and Safety of GENOSS® SES in Patients With Acute Coronary Syndrome (GENOSS ACS)
Genoss Co., Ltd. 757 participants Est. completion 2027-12-31 1 siteOther conditions: Acute Coronary Syndrome, Percutaneous Coronary InterventionView official trial listing → -
Terminated NCT NCT06078696
Siplizumab for Sickle Cell Disease Transplant
Not yet reported, Not yet reported Columbia University 1 participants Est. completion 2025-12-11 1 site Stand-aloneOther conditions: Anemia, Sickle CellView official trial listing → -
Withdrawn NCT NCT06080165
Sirolimus for Improving Social Abilities in People With PTEN Germline Mutations
Not yet reported, Not yet reported Stanford University Est. completion 2028-06 3 sites Stand-aloneOther conditions: PTEN Gene Mutation, PTEN Hamartoma Tumor Syndrome, PTEN Hamartoma SyndromeView official trial listing → -
Enrolling by invitation NCT NCT06086496
Effectiveness and Safety of Abluminal Biodegradable Polymer Sirolimus-eluting Stent (GENOSS® DES)
Genoss Co., Ltd. 1000 participants Est. completion 2027-12-31 1 siteCardiovascular disease Other conditions: Percutaneous Coronary InterventionView official trial listing → -
Active, not recruiting NCT NCT06105632
A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment
Not yet reported Pfizer 333 participants Est. completion 2028-01-21 48 sitesOther conditions: Advanced or Metastatic Breast CancerView official trial listing → -
Not yet recruiting NCT NCT06122974
Drug Eluting Temporary Spur Stent System vs Percutaneous Balloon Angioplasty for the Treatment of Critical Limb Ischemia
Not yet reported ReFlow Medical, Inc. 518 participants Est. completion 2037-12Other conditions: Critical Limb IschemiaView official trial listing → -
Active, not recruiting NCT NCT06145282
Non-myeloablative Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ Function
Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 6 participants Est. completion 2027-11-26 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Status unknown NCT NCT06160739
Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular Malformations
Sohag University 10 participants Est. completion 2024-09-01 1 siteOther conditions: Microcystic Lymphatic Malformation, Combined Vascular Malformation, Vascular MalformationsView official trial listing → -
Enrolling by invitation NCT NCT06168305
Safety and Effectiveness of GENOSS® DES in Patients With Multivessel Coronary Artery Disease
Genoss Co., Ltd. 1000 participants Est. completion 2028-02-28 1 siteCardiovascular disease Other conditions: Percutaneous Coronary InterventionView official trial listing → -
Status unknown NCT NCT06197022
Scoring-Balloon Angioplasty and Sirolimus-Eluting Balloon Angioplasty for the Treatment of Diffuse, Small Vessel Coronary Artery Disease (SCA-DEB Study)
Not yet reported University National Heart Hospital 106 participants Est. completion 2024-12 1 siteCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT06214819
Plan to Evaluate Early Endothelialization of a Polymer Free Sirolimus-eluting Coronary Stent System (VIVO ISARTM) Compared With Everolimus-eluting Durable Polymer Stent (XIENCE SkypointTM) in Patients Undergoing Percutaneous Coronary Intervention.
Not yet reported Fundación EPIC 40 participants Est. completion 2026-08-31 4 sitesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT06225206
Analysis of Donor-derived Cell Free DNA in Liver Transplant Patients
Methodist Health System 300 participants Est. completion 2024-12-31 1 siteOther conditions: Liver Transplant FailureView official trial listing → -
Completed NCT NCT06235905
Open-Label of SPN-820 in Adults With Major Depressive Disorder
Not yet reported Navitor Pharmaceuticals, Inc. 40 participants Est. completion 2024-08-18 1 siteOther conditions: Major Depressive DisorderView official trial listing → -
Active, not recruiting NCT NCT06239480
SELVA: A Phase 3 Study Evaluating QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations
Not yet reported Palvella Therapeutics, Inc. 51 participants Est. completion 2026-07 15 sitesOther conditions: Microcystic Lymphatic MalformationView official trial listing → -
Enrolling by invitation NCT NCT06257420
Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic Conditions
Simmaron Research Inc. 150 participants Est. completion 2027-07-01 5 sitesOther conditions: Myalgic Encephalomyelitis, Long-COVIDView official trial listing → -
Status unknown NCT NCT06279494
Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors
Not yet reported, Not yet reported Peking University People's Hospital 6 participants Est. completion 2025-03 Stand-aloneOther conditions: Acute Leukemia, Myelodysplastic Syndromes, Severe Aplastic AnemiaView official trial listing → -
Not yet recruiting NCT NCT06300268
Advapro Coronary Stent System in Coronary Artery Diseased Patients.
Not yet reported Advanced MedTech Solutions Pvt. Ltd. 120 participants Est. completion 2026-12Cardiovascular disease Other conditions: De Novo Stenosis Lesion, Coronary Stent ImplantationView official trial listing → -
Not yet recruiting NCT NCT06301386
Everolimus Combined With PD-1 in Advanced Colorectal Cancer Patients
Not yet reported Fudan University 25 participants Est. completion 2026-12-01 2 sitesOther conditions: Colon CancerView official trial listing → -
Active, not recruiting NCT NCT06308419
A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions
Not yet reported M.D. Anderson Cancer Center 18 participants Est. completion 2031-02-01 1 site Stand-aloneObstructive sleep apnea Other conditions: Soft-tissue SarcomasView official trial listing → -
Not yet recruiting NCT NCT06308445
Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis
Not yet reported University Hospital, Toulouse 25 participants Est. completion 2030-09 4 sitesOther conditions: Familial Adenomatous PolyposisView official trial listing → -
Status unknown NCT NCT06317298
Fruquintinib Plus Everolimus as 2nd Line Therapy of ccRCC Patients Progressed Post IO and TKI Therapy
Not yet reported Peking University First Hospital 36 participants Est. completion 2025-12-01 1 siteOther conditions: Renal Cell Carcinoma, Clear Cell, SomaticView official trial listing → -
Status unknown NCT NCT06338306
Tacrolimus and Personalized Therapy to Prevent Acute Rejection Episodes
Fondazione IRCCS Policlinico San Matteo di Pavia 25 participants Est. completion 2025-06-30 1 siteOther conditions: Heart Transplant FailureView official trial listing → -
Status unknown NCT NCT06340373
Clinical and Angiographic Outcomes of Post-drug-coated Balloon Angioplasty in Native Coronary Lesions
National Institute of Cardiovascular Diseases, Bangladesh 303 participants Est. completion 2025-06-30 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT06341998
Clinical Study of Chemotherapy in the Treatment of Recurrent/Refractory Yolk Sac Tumor in Children
Not yet reported, Not yet reported Shandong First Medical University 32 participants Est. completion 2024-02-01 1 site Stand-aloneOther conditions: Germ Cell Tumor, Yolk Sac TumorView official trial listing → -
Status unknown NCT NCT06345209
Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for Coronary Small Vessels
Not yet reported BrosMed Medical Co., Ltd 236 participants Est. completion 2025-12 Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT06409507
Research and Application for New Clinical Diagnosis and Treatment System for HBV Related HCC Liver Transplantation
First People's Hospital of Hangzhou 178 participants Est. completion 2023-08-01Other conditions: Hepatocellular Carcinoma, Liver Transplantation, PrognosisView official trial listing → -
Active, not recruiting NCT NCT06428396
Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)
Not yet reported Merck Sharp & Dohme LLC 120 participants Est. completion 2028-12-25 41 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Active, not recruiting NCT NCT06494150
Nab-Sirolimus and Endocrine Therapy in Recurrent Low Grade Serous Ovarian Cancer (NARETO)
Not yet reported University of Oklahoma 37 participants Est. completion 2029-09 1 site Stand-aloneOther conditions: Low Grade Ovarian Serous AdenocarcinomaView official trial listing → -
Status unknown NCT NCT06504225
EVEROLD LONG TERM FOLLOW-UP
University Hospital, Brest 260 participants Est. completion 2025-08-01 14 sitesOther conditions: Transplant; Complication, FailureView official trial listing → -
Completed NCT NCT06550271
The Bioavailability of Compounded and Generic Rapamycin in Normative Aging Individuals
AgelessRx 67 participants Est. completion 2023-12-15 1 siteOther conditions: AgingView official trial listing → -
Status unknown NCT NCT06561022
Precision Treatment of HR+ HER2- Advanced Breast Cancer Based on SNF Molecular Subtyping
Not yet reported Fudan University 260 participants Est. completion 2026-06-30 1 siteOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT06563817
The Safety and Efficacy of Rapamycin on Communicating Hydrocephalus Secondary to Intraventricular Hemorrhage
Not yet reported Beijing Tiantan Hospital 53 participants Est. completion 2025-07 1 site Stand-aloneOther conditions: Communicating Hydrocephalus, Cerebral Intraventricular Hemorrhage, Secondary Normal Pressure Hydrocephalus, Post Hemorrhagic HydrocephalusView official trial listing → -
Status unknown NCT NCT06584773
Efficacy of a Quadruple Immunosuppressor Regimen With mTOR Inhibitors in Sensitized Kidney Transplant Patients
Not yet reported University of Sao Paulo General Hospital 80 participants Est. completion 2025-07 1 siteOther conditions: Disorder Related to Renal TransplantationView official trial listing → -
Not yet recruiting NCT NCT06607198
Clinical-pathological Evaluation of Pit-NETs
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 940 participants Est. completion 2026-10-01 1 siteOther conditions: Pituitary, Cancer, Neuroendocrine TumorsView official trial listing → -
Not yet recruiting NCT NCT06614972
Balloon-expandable DES for ICAS Registry Study (BDES-ICAS Registry)
RenJi Hospital 520 participants Est. completion 2030-09-30Cardiovascular disease Other conditions: Atheroscleroses, Cerebral, Intracranial AtherosclerosisView official trial listing → -
Active, not recruiting NCT NCT06621524
EucaLimus Post-Market Registry
OrbusNeich 251 participants Est. completion 2029-01 10 sitesOther conditions: Coronary ArteriosclerosesView official trial listing → -
Active, not recruiting NCT NCT06653842
A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Cutaneous Venous Malformations
Not yet reported Palvella Therapeutics, Inc. 15 participants Est. completion 2026-03 10 sitesOther conditions: Cutaneous Venous MalformationsView official trial listing → -
Active, not recruiting NCT NCT06680921
A Study of SIM0270 Combined With Everolimus vs. Treatment of Physician's Choice in Patients With ER+/HER2- Advanced Breast Cancer (SIMRISE)
Not yet reported Jiangsu Simcere Pharmaceutical Co., Ltd. 482 participants Est. completion 2028-08-31 57 sitesOther conditions: Locally Advanced or Metastatic Breast CancerView official trial listing → -
Not yet recruiting NCT NCT06682611
Safety and Efficacy of SYHA1813 Single Agent or in Combination With Different Regimens in Unresectable Locally Advanced or Metastatic Solid Tumors.
Not yet reported, Not yet reported Shanghai Runshi Pharmaceutical Technology Co., Ltd 380 participants Est. completion 2027-11-13Other conditions: Unresectable Locally Advanced or Metastatic Solid TumorsView official trial listing → -
Not yet recruiting NCT NCT06682767
A Nutritional and Pharmacological Intervention for Body, Brain, and Longevity Effects (NIBBLE)
Not yet reported, Not yet reported Cedars-Sinai Medical Center 60 participants Est. completion 2028-06 1 siteOther conditions: Cerebral Blood Flow, APOE 4View official trial listing → -
Status unknown NCT NCT06683118
Registration Trial of the Drug-coated Balloon for the Symptomatic Cerebral Atherosclerotic Stenosis
Not yet reported MicroPort NeuroTech Co., Ltd. 212 participants Est. completion 2026-07-27 2 sitesOther conditions: Cerebral Atherosclerotic StenosisView official trial listing → -
Not yet recruiting NCT NCT06708455
Phase 2b of RAPA-201 Cell Therapy in Post-PD-(L)-1 Melanoma
Not yet reported Rapa Therapeutics LLC 65 participants Est. completion 2029-09-30 1 siteOther conditions: Malignant Melanoma With Metastasis, Malignant Melanoma, Malignant Melanoma Stage IIIc, Malignant Melanoma Stage IVView official trial listing → -
Active, not recruiting NCT NCT06752694
Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia
Not yet reported Fred Hutchinson Cancer Center 1 participants Est. completion 2026-10-15 1 site Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Active, not recruiting NCT NCT06789900
Everolimus and/or Exercise to Prevent Bone Loss in Postmenopausal Women
Not yet reported Odense University Hospital 136 participants Est. completion 2026-10-01 1 siteOther conditions: Postmenopausal WomenView official trial listing → -
Active, not recruiting NCT NCT06821542
A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy
Not yet reported Incyte Corporation 9 participants Est. completion 2032-11-30 130 sitesOther conditions: Chronic Graft-versus-host-diseaseView official trial listing → -
Active, not recruiting NCT NCT06841510
Efficacy and Safety of GENOSS SES in Patients With Coronary Artery Disease
Genoss Co., Ltd. 1118 participants Est. completion 2025-11-30 1 siteOther conditions: Coronary Arterial Disease (CAD)View official trial listing → -
Enrolling by invitation NCT NCT06843811
Sirolimus for Leigh Syndrome
Not yet reported Matthew Demczko 15 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Leigh SyndromeView official trial listing → -
Withdrawn NCT NCT06857045
Comparison Three vs Six Months of Dual Anti-platelet Therapy After Sirolimus-eluting Stent Implantation
Not yet reported Sino Medical Sciences Technology Inc. Est. completion 2026-06 1 site Stand-aloneOther conditions: Intracranial Arteriosclerosis, Intracranial Artery Stenosis, Drug-Eluting StentsView official trial listing → -
Suspended NCT NCT06876142
Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma
Not yet reported, Not yet reported National Cancer Institute (NCI) 54 participants Est. completion 2033-01-01 1 site Stand-aloneOther conditions: Multiple Myeloma, Relapsed and/or Refractory Multiple Myeloma (RRMM)View official trial listing → -
Completed NCT NCT06914089
Thin Versus Thicker Strut Thickness Stents in Primary Percutaneous Intervention
Not yet reported Assiut University 146 participants Est. completion 2023-09-30 1 siteOther conditions: Primary Percutaneous Coronary InterventionView official trial listing → -
Not yet recruiting NCT NCT06925971
A Randomized Trial of the Rapamycin Target Eluting Stent for the Treatment of Symptomatic Cerebral Artery Atherosclerotic Disease(TARGET-DREAM)
Not yet reported MicroPort NeuroTech Co., Ltd. 279 participants Est. completion 2027-10-01 1 siteOther conditions: Intracranial ArteriosclerosisView official trial listing → -
Not yet recruiting NCT NCT06928883
Ticin Pilot Study: Sirolimus-Eluting Balloon for Stabilization and Regression of Non-Obstructive Coronary Plaques.
Not yet reported Cardiocentro Ticino 24 participants Est. completion 2028-12-31 1 site Stand-aloneCardiovascular disease Other conditions: Coronary Arterial Disease (CAD), Vulnerable Coronary Plaques, Coronary Vessel, Acute Coronary Syndromes (ACS)View official trial listing → -
Not yet recruiting NCT NCT06929325
Sirolimus for Injection (Albumin-bound) Combined With Fulvestrant for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Previously Treated With CDK4/6 Inhibitors
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 312 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: HR+/HER2- Advanced/Metastatic Breast CancerView official trial listing → -
Completed NCT NCT06940895
Evaluating the Safety and Efficacy of Topical Sirolimus 0.2% to Treat Acanthosis Nigricans
Not yet reported Narrows Institute for Biomedical Research 5 participants Est. completion 2025-07-18 1 site Stand-aloneOther conditions: Acanthosis NigricansView official trial listing → -
Not yet recruiting NCT NCT06941142
A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast Cancer
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 382 participants Est. completion 2028-06 Stand-aloneOther conditions: Advanced Breast CancerView official trial listing → -
Not yet recruiting NCT NCT06942156
Optimize Immunosuppressive Therapy Using Everolimus and Low-dose Calcineurin Inhibitors in Heart Transplant Patients in Korea
Not yet reported Chong Kun Dang Pharmaceutical 140 participants Est. completion 2030-12 1 siteOther conditions: Heart TransplantView official trial listing → -
Active, not recruiting NCT NCT06957379
Sirolimus for Injection (Albumin-bound) in Combination With Endocrine Therapy for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Who Have Failed Standard Therapy
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 78 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: HR+/HER2- Advanced/Metastatic Breast CancerView official trial listing → -
Not yet recruiting NCT NCT06981845
Sirolimus With corTicOsteroid TheraPy for Rapid rEcurrences of Coronary Unexplained In-stent Restenosis
Not yet reported China National Center for Cardiovascular Diseases 52 participants Est. completion 2028-06-01 Stand-aloneCardiovascular disease Other conditions: In-stent Restenosis LesionView official trial listing → -
Not yet recruiting NCT NCT06994572
Study of CT-01 as Monotherapy and Combination Therapy in Subjects With Intermediate or Advanced Hepatocellular Carcinoma
Not yet reported Captor Therapeutics S.A. 141 participants Est. completion 2030-04-01Other conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Active, not recruiting NCT NCT07054320
Rapamycin and Infection-related Illness
Hoskinson Health and Wellness Clinic 15 participants Est. completion 2026-06 1 siteOther conditions: Infectious DiseasesView official trial listing → -
Active, not recruiting NCT NCT07058974
A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation
Not yet reported Icahn School of Medicine at Mount Sinai 20 participants Est. completion 2027-06-15 1 site Stand-aloneOther conditions: Smokers, Former SmokersView official trial listing → -
Not yet recruiting NCT NCT07081763
Immunotherapy With Baricitinib and Sirolimus, Alone and in Combination, for the Control of HIV-1 Replication After Antiretroviral Treatment Interruption
Not yet reported ANRS, Emerging Infectious Diseases 191 participants Est. completion 2030-11 Stand-aloneOther conditions: HIV-1-infectionView official trial listing → -
Enrolling by invitation NCT NCT07113743
Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 10 participants Est. completion 2029-09-01 1 site Stand-aloneOther conditions: Chronic Granulomatous Disease (CGD)View official trial listing → -
Active, not recruiting NCT NCT07151157
Therapeutic Value of Sirolimus in Refractory Adult-Onset Still's Disease
Not yet reported Ruijin Hospital 3 participants Est. completion 2026-08-30 1 site Stand-aloneOther conditions: Adult-Onset Still's DiseaseView official trial listing → -
Enrolling by invitation NCT NCT07159087
The Safety and Efficacy for In-segment Late Lumen Loss of the 'Genoss® SCB' Versus 'SeQuent® Please NEO' in Patients With Coronary ISR
Not yet reported Genoss Co., Ltd. 94 participants Est. completion 2027-01-31 1 site Stand-aloneOther conditions: Coronary Arterial Disease (CAD)View official trial listing → -
Not yet recruiting NCT NCT07166354
Clinical Study of mTOR Inhibitor as a Treatment for Grey Hair (Canities)
Not yet reported, Not yet reported Applied Biology, Inc. 100 participants Est. completion 2027-09-15Other conditions: Canities, Grey HairView official trial listing → -
Not yet recruiting NCT NCT07173556
A Phase Ib/II Study of QLC1401 Combined With CDK4/6 or mTOR Inhibitors in ER+/HER2- Advanced Breast Cancer
Not yet reported, Not yet reported Qilu Pharmaceutical Co., Ltd. 96 participants Est. completion 2028-10Other conditions: Advanced Breast CancerView official trial listing → -
Not yet recruiting NCT NCT07203664
Use of Tacrolimus and MTOR Inhibitors With Anticipatory Therapy vs. Tacrolimus and Mycophenolic Acid With Universal Prophylaxis in Renal Recipients at High Risk of Posttransplant Cytomegalovirus.
Not yet reported Hospital Universitario La Paz 30 participants Est. completion 2026-12-31 1 siteOther conditions: Evaluate the Effectiveness of CMV Prevention Strategies in Kidney Transplant RecipientsView official trial listing → -
Not yet recruiting NCT NCT07218575
Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations
Not yet reported, Not yet reported Boston Children's Hospital 60 participants Est. completion 2030-09 3 sitesOther conditions: Cowden's Disease, Cowden's Syndrome, Lhermitte-Duclos Disease, Cerebellum Dysplastic Gangliocytoma, Bannayan Zonana Syndrome, Myhre Riley Smith Syndrome, Riley Smith Syndrome, PTEN Hamartoma Tumor Syndrome, Bannayan Riley Ruvalcaba SyndromeView official trial listing → -
Completed NCT NCT07302932
Metformin and Molecular Aging in Prediabetes
Not yet reported Diabetes Foundation, India 112 participants Est. completion 2025-01-30 1 sitePrediabetesView official trial listing → -
Completed NCT NCT07326735
MIRAGE Study: Clinical Outcomes of the Mamba Sirolimus-Eluting PTCA Balloon
Not yet reported Frisch Medical Device Private Limited 360 participants Est. completion 2024-03-03 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT07329088
Isoleucine Addition Treatment Effects in a Controlled Diet Study
Not yet reported Jean L. Fry Est. completion 2029-01-31 1 sitePrediabetesMetabolic syndrome Other conditions: Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07350057
A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in Children
Not yet reported Shanghai Jiao Tong University School of Medicine 9 participants Est. completion 2027-12-01 Stand-aloneOther conditions: GVHD (Acute or Chronic)View official trial listing → -
Active, not recruiting NCT NCT07354620
A Pilot Study on Reverse Aging (The REVERSE Study)
Not yet reported The Christ Hospital 52 participants Est. completion 2026-05 1 siteOther conditions: AgingView official trial listing → -
Not yet recruiting NCT NCT07359807
A Study Comparing the MAGICTouch™ Sirolimus-coated Balloon With a Paclitaxel-coated Balloon for Treating Severe Narrowing or Blockage in the Femoropopliteal Arteries.
Not yet reported, Not yet reported Concept Medical Inc. 478 participants Est. completion 2033-01 Stand-aloneOther conditions: Popliteal Artery Disease, Superficial Femoral Artery DiseaseView official trial listing → -
Not yet recruiting NCT NCT07407517
Adjuvant Intensification for LAR
Not yet reported Fudan University 904 participants Est. completion 2033-02-01Other conditions: Breast Cancer Females, Triple Negative Breast Cancer (TNBC)View official trial listing → -
Not yet recruiting NCT NCT07408674
COMPETE-LM Trial: Drug-Coated Balloon-Enhanced Provisional Stenting in Complex Left Main Disease.
Not yet reported Rede Optimus Hospitalar SA 186 participants Est. completion 2029-05Other conditions: Complex Left Main Bifurcation Stenosis, Left Main Coronary Artery Stenosis, Coronary Bifurcation StenosisView official trial listing → -
Not yet recruiting NCT NCT07435584
Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE)
Not yet reported, Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 38 participants Est. completion 2028-12-31Other conditions: Colorectal CancerView official trial listing → -
Not yet recruiting NCT NCT07436611
Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains
Not yet reported AFT Pharmaceuticals, Ltd. 30 participants Est. completion 2027-10 2 sitesOther conditions: Port Wine StainsView official trial listing → -
Active, not recruiting NCT NCT07475546
Combination Gerotherapeutic Interventions for Healthspan Improvement
Not yet reported AgelessRx 30 participants Est. completion 2026-04 1 siteOther conditions: Healthspan Improvement, Aging, LongevityView official trial listing → -
Not yet recruiting NCT NCT07477548
A Study to Evaluate the Efficacy and Safety of Everolimus in Patients With Teratment-refractory Vascular Anomalies
Not yet reported Yonsei University 67 participants Est. completion 2030-11-30Other conditions: Vascular Malformations, Arteriovenous Malformations, Venous Malformation, Lymphangioma, Nevus, Port-Wine, Hemangioendothelioma, HemangiomaView official trial listing → -
Not yet recruiting NCT NCT07514988
Sirolimus-Coated vs Paclitaxel-Coated DCBs in ACS Treatment
Not yet reported China National Center for Cardiovascular Diseases 60 participants Est. completion 2028-07-01 1 site Stand-aloneOther conditions: Acute Coronary Syndromes (ACS)View official trial listing → -
Not yet recruiting NCT NCT07518277
A Multicenter, Prospective, Randomized Controlled Study Comparing Glucocorticoid Combined With Sirolimus With Monotherapy of Glucocorticoid in the Treatment of Newly Diagnosed Mild Autoimmune Hemolytic Anemia
Not yet reported Chen Miao 216 participants Est. completion 2028-04-01 1 site Stand-aloneOther conditions: Autoimmune Hemolytic Anemia (AIHA)View official trial listing → -
Not yet recruiting NCT NCT07542314
Study to Evaluate the Safety and Effectiveness of ELEVIDYS in Participants With Duchenne Muscular Dystrophy Treated in a Post-Marketing Setting
Not yet reported Sarepta Therapeutics, Inc. 20 participants Est. completion 2027-08-31 1 siteOther conditions: Duchenne Muscular DystrophyView official trial listing → -
Not yet recruiting NCT NCT07563231
Polymer-free Sirolimus Eluting Stent: Real-world Investigation of Safety and Outcomes
Dorian Garin 300 participants Est. completion 2036-06 1 siteCardiovascular disease Other conditions: Acute Coronary Syndrome, Stent Thrombosis, Percutaneous Coronary InterventionView official trial listing → -
Not yet recruiting NCT NCT07566091
Noninferiority Trial Of Sirolimus With Ascorbic Acid Versus Everolimus in All-comers
Not yet reported Jung-min Ahn 2034 participants Est. completion 2028-06-15 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07570433
HORUS-Cytomegalovirus Open Proof-of-concept Exploratory Trial
Not yet reported Oriol Manuel 100 participants Est. completion 2028-03 4 sitesOther conditions: CMV InfectionView official trial listing → -
Not yet recruiting NCT NCT07587801
Vaccination Response Modulation With a Targeted Rapamycin Protocol Study
Not yet reported Central Adelaide Local Health Network Incorporated 60 participants Est. completion 2026-07 3 sites Stand-aloneOther conditions: Vaccine Immune Response, Haemodialysis Patients, Older AdultsView official trial listing → -
Not yet recruiting NCT NCT07619950
EVERolimus and LenvAtinib Versus Everolimus for Bone Sarcoma
Not yet reported Yonsei University 94 participants Est. completion 2028-11-30Other conditions: Neoplasms of Bone and Articular Cartilage With Unspecified Anatomical SiteView official trial listing → -
Not yet recruiting NCT NCT07634120
Vertebrobasilar Dolichoectasia Treatment With Sirolimus
Not yet reported Huashan Hospital 12 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Vertebrobasilar DolichoectasiaView official trial listing → -
Not yet recruiting NCT NCT07634601
Elacestrant With Everolimus for the Treatment of Recurrent Advanced or Metastatic ER-Positive Endometrial Cancer
Not yet reported Jonsson Comprehensive Cancer Center 50 participants Est. completion 2029-12-18 1 siteOther conditions: Advanced Endometrial Carcinoma, Metastatic Endometrial Carcinoma, Recurrent Endometrial Carcinoma, Stage III Endometrial Cancer, Stage IV Endometrial CancerView official trial listing → -
Active, not recruiting NCT NCT07649798
Initial Study of a MOTHER-DAUGHTER SIDE-BRANCH ACCESS™ DES System (FIH Feasibility Study)
Not yet reported Advanced Bifurcation Systems Inc. 13 participants Est. completion 2028-11-19 1 site Stand-aloneCardiovascular disease Other conditions: Coronary Angioplasty, Ischemic Heart Disease (IHD), Percutaneous Coronary Intervention (PCI)View official trial listing → -
Not yet recruiting NCT NCT07662174
Ventricular mTOR Inhibition to Prevent Hydrocephalus After Brain Hemorrhage
Not yet reported, Not yet reported Massachusetts General Hospital 15 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Post-hemorrhagic Hydrocephalus (PHH)View official trial listing → -
Not yet recruiting NCT NCT07667413
Topical TOR-582 Treatment of Epistaxis in HHT
Not yet reported Columbia University 27 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Hereditary Hemorrhagic Telangiectasia (HHT), EpistaxisView official trial listing → -
Not yet recruiting NCT NCT07680322
Safety and Efficacy of AV078 in Participants With Tuberous Sclerosis Complex (TSC) Refractory Epilepsy (RESTOR-1)
Not yet reported Aeovian Pharmaceuticals, Inc. 42 participants Est. completion 2027-12-21 1 siteOther conditions: Tuberous Sclerosis Complex, EpilepsyView official trial listing → -
Not yet recruiting NCT NCT07684287
A Phase 2 Study of Sirolimus for Injection (Albumin-bound) in Patients With Progressive or Symptomatic Epithelioid Hemangioendothelioma
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 40 participants Est. completion 2027-11-30 1 site Stand-aloneOther conditions: Epithelioid HemangioendotheliomaView official trial listing → -
Available NCT NCT07689942
Expanded Access to 0.5 mg eRapa for Familial Adenomatous Polyposis
Biodexa PharmaceuticalsOther conditions: Familial Adenomatous Polyposis (FAP)View official trial listing → -
Not yet recruiting NCT NCT07715734
Cemiplimab for Kidney Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma
Not yet reported Washington University School of Medicine 22 participants Est. completion 2031-03-31 1 site Stand-aloneOther conditions: Kidney Transplant Recipient, Cutaneous Squamous Cell Carcinoma (CSCC), Advanced Cutaneous Squamous Cell Carcinoma, Kidney TransplantView official trial listing → -
Not yet recruiting NCT NCT07728175
Effects of Sirolimus on Asymptomatic ApoE4 Carriers
Not yet reported University of Missouri-Columbia 225 participants Est. completion 2028-07-07 1 siteOther conditions: Genetic Predisposition to Disease, Healthy Volunteer, APOE-4 PositiveView official trial listing → -
Not yet recruiting NCT NCT07735533
A Phase 1/2 Study of UB-VV400 With Rapamycin in Relapsed/Refractory B-cell Malignancies
Not yet reported, Not yet reported Umoja Biopharma 274 participants Est. completion 2031-08 Stand-aloneOther conditions: Lymphoma, B Cell, Lymphoma Non-Hodgkin, High Grade B Cell Lymphoma, Richter Transformation Lymphoma, Grade 3b Follicular Lymphoma, Primary Mediastinal B Cell Lymphoma, Diffuse Large B Cell Lymphoma (DLBCL)View official trial listing → -
Not yet recruiting NCT NCT07735546
A Phase 1 Study of UB-VV500 With Rapamycin in Relapsed/Refractory Multiple Myeloma
Not yet reported Umoja Biopharma 100 participants Est. completion 2029-12-31 Stand-aloneOther conditions: Multiple Myeloma in Relapse, Multiple Myeloma (MM)View official trial listing → -
Not yet recruiting NCT NCT07739914
Everolimus bAsed caLcineurin inhibiTor frEe immunosuppRession oNe Year AfTer lIver transplantatiON (ALTERNATION)
Not yet reported Hannover Medical School 150 participants Est. completion 2031-06-30 16 sitesOther conditions: Liver Allograft, Liver Diseases, Liver TransplantationView official trial listing → -
Not yet recruiting NCT NCT07767877
A Study of Clinical Practice and Real-world Care of Patients Treated With mTOR, PI3K, and MEK Inhibitors for Extracranial Vascular Anomalies
Novartis Pharmaceuticals 200 participants Est. completion 2027-10-29Other conditions: Vascular AnomaliesView official trial listing → -
Not yet recruiting NCT NCT07796412
IVUS-Guided Sirolimus-Coated Balloon Versus Sirolimus-Eluting Stent for De Novo Large Vessel Lesions in ACS
Not yet reported China National Center for Cardiovascular Diseases 150 participants Est. completion 2028-05-01 1 site Stand-aloneOther conditions: Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)View official trial listing → -
Not yet recruiting NCT NCT07796620
Sirolimus+Ruxolitinib+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to CNI
Not yet reported, Not yet reported Peking University People's Hospital 40 participants Est. completion 2028-09-30 Stand-aloneOther conditions: Acute Leukemia, Myelodysplastic Syndromes, Severe Aplastic Anemia (SAA)View official trial listing → -
Not yet recruiting NCT NCT07811232
A Study of AL58805 in Advanced, Metastatic GYN, STS or Breast Cancers
Not yet reported, Not yet reported Advenchen Pharmaceuticals, LLC. 138 participants Est. completion 2031-09-01 1 siteOther conditions: Endometrial Neoplasms, Soft Tissue Sarcoma (STS), Breast NeoplasmsView official trial listing → -
Not yet recruiting NCT NCT07811297
A Study of Catequentinib Hydrochloride (AL3818) in Endometrial, LGSOC, STS or GBM Cancers
Not yet reported, Not yet reported Advenchen Pharmaceuticals, LLC. 138 participants Est. completion 2031-09-01 1 siteOther conditions: Endometrial Neoplasms, Ovarian Neoplasms, Soft Tissue Sarcoma (STS), GlioblastomaView official trial listing → -
Not yet recruiting NCT NCT07813533
A Pilot Study to Examine the Efficacy and Tolerability of Sirolimus on Epidermal Nevi Lesions in Patients 6 Years Old and Above.
Not yet reported Northwestern University 14 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Epidermal NeviView official trial listing → -
Completed NCT NCT07820579
Sirolimus Treatment in Pediatric Patients With Ataxia-Telangiectasia
Not yet reported Sara Elva Espinosa Padilla, MD 6 participants Est. completion 2026-08-20 1 site Stand-aloneOther conditions: Ataxia-Telangiectasia (A-T), Ataxia-TelangiectasiaView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Sirolimus, Rapamune (sirolimus/rapamycin)
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
