GLP-1 Market
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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Sirolimus

Company
National Human Genome Research Institute (NHGRI)
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
189 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

189 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Oct 1, 2026

Find a Clinical Trial Near Me

See recruiting studies for Sirolimus and check eligibility with the study team.

Select conditions
Match
Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT01241864

    Islet Transplantation in Type 1 Diabetic Kidney Allograft

    Not yet reported University of Chicago 10 participants Est. completion 2026-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Recruiting NCT NCT02029001

    Adapting Treatment to the Tumor Molecular Alterations for Patients With Advanced Solid Tumors: MyOwnSpecificTreatment

    Not yet reported Centre Leon Berard 900 participants Est. completion 2028-10 7 sites
    Other conditions: Malignant Solid Neoplasms
    View official trial listing →
  • Recruiting NCT NCT02042326

    Prospective Evaluation of the Efficacy of Sirolimus (Rapamune®) in the Treatment of Severe Arteriovenous Malformations

    Not yet reported Centre Hospitalier Universitaire, Amiens 50 participants Est. completion 2027-09 13 sites Stand-alone
    Other conditions: Arteriovenous Malformations
    View official trial listing →
  • Recruiting NCT NCT02432560

    Safety and Durability of Sirolimus for Treatment of LAM

    University of Cincinnati 600 participants Est. completion 2025-07-31 20 sites
    Other conditions: Lymphangioleiomyomatosis
    View official trial listing →
  • Recruiting NCT NCT02446431

    Metronomic Therapy for Pediatric Patients With Solid Tumors at High Risk of Recurrence

    Not yet reported Miller Children's & Women's Hospital Long Beach 20 participants Est. completion 2029-07 2 sites Stand-alone
    Other conditions: Solid Tumor
    View official trial listing →
  • Recruiting NCT NCT02579967

    Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

    Not yet reported National Cancer Institute (NCI) 354 participants Est. completion 2036-12-31 2 sites Stand-alone
    Other conditions: Primary T-cell Immunodeficiency Disorders, Common Variable Immunodeficiency, Immune System Diseases, Autoimmune Lymphoproliferative, Lymphoproliferative Disorders
    View official trial listing →
  • Recruiting NCT NCT02638389

    Efficacy and Safety of Sirolimus in Vascular Anomalies That Are Refractory to Standard Care

    Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 250 participants Est. completion 2030-04-01 3 sites Stand-alone
    Other conditions: Vascular Malformations
    View official trial listing →
  • Recruiting NCT NCT02693535

    TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

    Not yet reported American Society of Clinical Oncology 4200 participants Est. completion 2028-12-31 181 sites
    Other conditions: Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid Tumors
    View official trial listing →
  • Recruiting NCT NCT02813135

    European Proof-of-Concept Therapeutic Stratification Trial of Molecular Anomalies in Relapsed or Refractory Tumors

    Not yet reported, Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 472 participants Est. completion 2031-02 23 sites
    Other conditions: Pediatric Cancer
    View official trial listing →
  • Recruiting NCT NCT03121001

    Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease

    Not yet reported University of Illinois at Chicago 50 participants Est. completion 2029-05 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Recruiting NCT NCT03214354

    Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor

    Not yet reported University of Calgary 12 participants Est. completion 2028-07 1 site Stand-alone
    Other conditions: Sickle Cell Disease, Stem Cell Transplant Complications, Red Blood Cell Disorder, Pure Red Cell Aplasia
    View official trial listing →
  • Recruiting NCT NCT03243019

    Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations

    Not yet reported University Hospital, Lille 28 participants Est. completion 2027-02 2 sites Stand-alone
    Other conditions: Lymphatic Malformation, Pediatric
    View official trial listing →
  • Recruiting NCT NCT03297606

    Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)

    Not yet reported Canadian Cancer Trials Group 720 participants Est. completion 2027-01-31 10 sites
    Other conditions: Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid Tumors
    View official trial listing →
  • Recruiting NCT NCT03443999

    S-FLEX Netherlands Registry: Prospective Evaluation of the Supraflex Family Sirolimus-eluting Coronary Stent System

    Sahajanand Medical Technologies Limited 10000 participants Est. completion 2027-12 7 sites
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT03587272

    Minimizing Toxicity in HLA-identical Sibling Donor Transplantation for Children With Sickle Cell Disease

    Not yet reported Robert Nickel 100 participants Est. completion 2030-11 7 sites Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Recruiting NCT NCT03952637

    A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis

    Not yet reported, Not yet reported National Human Genome Research Institute (NHGRI) 54 participants Est. completion 2030-01-01 1 site Stand-alone
    Other conditions: Lysosomal Diseases, Gangliosidosis, GM1
    View official trial listing →
  • Recruiting NCT NCT03955172

    Efficiency of Everolimus for the Treatment of Kidney Transplanted Patients Presenting a Missing Self-induced NK-mediated Rejection

    Not yet reported Hospices Civils de Lyon 20 participants Est. completion 2027-12-03 1 site
    Other conditions: Kidney Transplant Failure and Rejection
    View official trial listing →
  • Recruiting NCT NCT03970096

    Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)

    Not yet reported Fred Hutchinson Cancer Center 120 participants Est. completion 2029-12-31 3 sites Stand-alone
    Other conditions: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm
    View official trial listing →
  • Recruiting NCT NCT04022616

    Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients

    Ohio State University Comprehensive Cancer Center 99 participants Est. completion 2027-12-31 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT04083183

    Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant Diseases

    Not yet reported, Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2028-01-09 1 site Stand-alone
    Other conditions: Non-Malignant Neoplasm
    View official trial listing →
  • Recruiting NCT NCT04141020

    Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms

    Not yet reported University of Miami 80 participants Est. completion 2026-11-01 1 site Stand-alone
    Other conditions: Cerebral Aneurysm
    View official trial listing →
  • Recruiting NCT NCT04199026

    Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

    Not yet reported M.D. Anderson Cancer Center 20 participants Est. completion 2028-12-31 1 site
    Other conditions: Metastatic Sarcoma, Recurrent Sarcoma, Resectable Sarcoma
    View official trial listing →
  • Recruiting NCT NCT04433572

    Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee

    Not yet reported Mercator MedSystems, Inc. 250 participants Est. completion 2032-08-01 2 sites
    Other conditions: Peripheral Artery Disease, Critical Limb Ischemia
    View official trial listing →
  • Recruiting NCT NCT04469530

    Sirolimus in Combination With Metronomic Chemotherapy in Children With High-Risk Solid Tumors

    Not yet reported Emory University 55 participants Est. completion 2029-02 5 sites Stand-alone
    Other conditions: Solid Tumor
    View official trial listing →
  • Recruiting NCT NCT04485559

    Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

    Not yet reported University of California, San Francisco 50 participants Est. completion 2027-12-31 17 sites
    Other conditions: Recurrent World Health Organization (WHO) Grade II Glioma, Low-grade Glioma, High-Grade Glioma (HGG)
    View official trial listing →
  • Recruiting NCT NCT04511234

    Sirolimus Coated Balloon Versus Standard Balloon for SFA and Popliteal Artery Disease

    Not yet reported Concept Medical Inc. 279 participants Est. completion 2026-12 20 sites Stand-alone
    Other conditions: Peripheral Artery Disease, Atherosclerosis, Arterial Disease
    View official trial listing →
  • Recruiting NCT NCT04511247

    SirolimUs CoaTed Balloon for The TrEatment of Below The Knee Arterial Disease

    Not yet reported Concept Medical Inc. 219 participants Est. completion 2027-12 20 sites Stand-alone
    Other conditions: Peripheral Artery Disease, Atherosclerosis, Arterial Disease of Legs
    View official trial listing →
  • Recruiting NCT NCT04584632

    The Efemoral Vascular Scaffold System (EVSS) for the Treatment of Patients With Symptomatic Peripheral Vascular Disease From Stenosis or Occlusion of the Femoropopliteal Artery

    Not yet reported Efemoral Medical, Inc. 100 participants Est. completion 2030-03 8 sites Stand-alone
    Other conditions: Peripheral Arterial Disease, Vascular Diseases, Stenosis, Femoropopliteal Stenosis
    View official trial listing →
  • Recruiting NCT NCT04665739

    Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

    Not yet reported National Cancer Institute (NCI) 70 participants Est. completion 2027-07-01 29 sites
    Other conditions: Advanced Lung Neuroendocrine Tumor, Functioning Lung Neuroendocrine Tumor, Locally Advanced Lung Neuroendocrine Neoplasm, Lung Neuroendocrine Neoplasm, Lung Neuroendocrine Tumor G1, Lung Neuroendocrine Tumor G2, Metastatic Lung Neuroendocrine Neoplasm, Metastatic Lung Neuroendocrine Tumor, Non-Functioning Lung Neuroendocrine Tumor, Recurrent Lung Neuroendocrine Neoplasm, Unresectable Lung Neuroendocrine Neoplasm, Unresectable Lung Neuroendocrine Tumor
    View official trial listing →
  • Recruiting NCT NCT04679740

    Resorbable Magnesium Scaffolds Registry

    Biotronik AG 1106 participants Est. completion 2030-05 13 sites
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT04802759

    A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer

    Not yet reported, Not yet reported Hoffmann-La Roche 316 participants Est. completion 2029-05-30 32 sites
    Other conditions: Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT04803318

    Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors

    Not yet reported Second Affiliated Hospital of Guangzhou Medical University 100 participants Est. completion 2037-01-01 1 site
    Other conditions: Solid Tumor, Adult, Hepatocellular Carcinoma
    View official trial listing →
  • Recruiting NCT NCT04861064

    Weekly Sirolimus Therapy

    Not yet reported Medical University of South Carolina 24 participants Est. completion 2027-12 1 site Stand-alone
    Other conditions: Venous Malformation, Lymphatic Malformation
    View official trial listing →
  • Recruiting NCT NCT04888741

    Methods of T Cell Depletion Trial (MoTD)

    Not yet reported University of Birmingham 400 participants Est. completion 2027-08-23 17 sites Stand-alone
    Other conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Chronic Myelogenous Leukemia, Myelofibrosis
    View official trial listing →
  • Recruiting NCT NCT04923191

    The PIONEER-IV Study is Comparing Clinical Outcomes Between Angiography-derived Physiology Guidance to Usual Care in an All-comers PCI Population With Unrestrictive Use of the HT Supreme Sirolimus-eluting Stent

    Not yet reported National University of Ireland, Galway, Ireland 2540 participants Est. completion 2029-01 19 sites
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT04936854

    Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease

    Not yet reported Haukeland University Hospital 60 participants Est. completion 2028-12 1 site
    Other conditions: Thyroid-Associated Ophthalmopathy
    View official trial listing →
  • Recruiting NCT NCT04948749

    Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial

    Not yet reported Beijing Tiantan Hospital 358 participants Est. completion 2027-12 18 sites Stand-alone
    Cardiovascular disease Other conditions: ICAD - Intracranial Atherosclerotic Disease, ICAS - Intracranial Atherosclerosis, Drug-eluting Stent, Drug Eluting Stents (DES), Medical Treatment
    View official trial listing →
  • Recruiting NCT NCT04959175

    Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

    Not yet reported, Not yet reported National Cancer Institute (NCI) 320 participants Est. completion 2027-04-30 2 sites Stand-alone
    Other conditions: Hematologic Neoplasms
    View official trial listing →
  • Recruiting NCT NCT04988685

    SIROOP Registry - A Prospective Registry Study to Evaluate the Outcomes of Coronary Artery Disease Patients Treated With SIROlimus Or Paclitaxel Eluting Balloon Catheters

    Luzerner Kantonsspital 2000 participants Est. completion 2031-12-31 1 site
    Cardiovascular disease Other conditions: Coronary Disease, Coronary Restenosis, Coronary Arteriosclerosis, Coronary Artery Calcification, Stable Chronic Angina, Angina Pectoris, Angina, Stable, Angina, Unstable, Stent Thrombosis
    View official trial listing →
  • Recruiting NCT NCT05009992

    Combination Therapy for the Treatment of Diffuse Midline Gliomas

    Not yet reported University of California, San Francisco 360 participants Est. completion 2029-06-30 32 sites
    Other conditions: Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, H3 K27M-Mutant, Recurrent Diffuse Intrinsic Pontine Glioma, Recurrent Diffuse Midline Glioma, H3 K27M-Mutant, Recurrent WHO Grade III Glioma, WHO Grade III Glioma
    View official trial listing →
  • Recruiting NCT NCT05036226

    COAST Therapy in Advanced Solid Tumors and Prostate Cancer

    Not yet reported, Not yet reported Medical University of South Carolina 76 participants Est. completion 2028-05-21 1 site Stand-alone
    Other conditions: Prostate Cancer Recurrent, Solid Tumor, Adult
    View official trial listing →
  • Recruiting NCT NCT05104983

    Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

    Not yet reported Darcy Krueger 64 participants Est. completion 2027-06-30 11 sites Stand-alone
    Other conditions: Tuberous Sclerosis Complex, Epilepsy
    View official trial listing →
  • Recruiting NCT NCT05105152

    PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML

    Not yet reported Seattle Children's Hospital 18 participants Est. completion 2041-01-31 1 site
    Other conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, in Relapse
    View official trial listing →
  • Recruiting NCT NCT05144698

    RAPA-201 Therapy of Solid Tumors

    Not yet reported, Not yet reported Rapa Therapeutics LLC 37 participants Est. completion 2026-12-31 1 site
    Other conditions: Solid Tumor, Small Cell and Non-small Cell Lung Cancer, Head and Neck Cancer, Squamous Cell Carcinoma of Oral Cavity, Squamous Cell Carcinoma of Larynx, Squamous Cell Carcinoma of Nasopharynx, Squamous Cell Carcinoma of Other Specified Sites of Skin, Malignant Melanoma, Esophageal Squamous Cell Carcinoma
    View official trial listing →
  • Recruiting NCT NCT05233722

    mTOR as Mediator of Insulin Sensitivity Study

    Not yet reported University of Copenhagen 10 participants Est. completion 2029-06 1 site
    Other conditions: Insulin Sensitivity
    View official trial listing →
  • Recruiting NCT NCT05237687

    The Role of Sirolimus in Preventing Functional Decline in Older Adults

    Not yet reported Irina Timofte 10 participants Est. completion 2028-01 1 site Stand-alone
    Other conditions: Aging
    View official trial listing →
  • Recruiting NCT NCT05327023

    Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

    Not yet reported, Not yet reported National Cancer Institute (NCI) 430 participants Est. completion 2029-07-02 1 site Stand-alone
    Other conditions: Hematologic Neoplasms
    View official trial listing →
  • Recruiting NCT NCT05351216

    The Effect of Sirolimus on Immunizations During the Treatment of Kaposiform Hemangioendothelioma

    Children's Hospital of Fudan University 174 participants Est. completion 2028-03 1 site
    Other conditions: Kaposiform Hemangioendothelioma
    View official trial listing →
  • Recruiting NCT NCT05414292

    Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune)

    Not yet reported University of Nottingham 16 participants Est. completion 2027-05-01 1 site Stand-alone
    Other conditions: Muscle Atrophy, Age-Related Sarcopenia
    View official trial listing →
  • Recruiting NCT NCT05426252

    Thal-Fabs: Reduced Toxicity Conditioning for High Risk Thalassemia

    Not yet reported, Not yet reported The Hospital for Sick Children 20 participants Est. completion 2026-12-31 1 site Stand-alone
    Other conditions: Thalassemia in Children
    View official trial listing →
  • Recruiting NCT NCT05432518

    Pilot Trial for Treatment of Recurrent Glioblastoma

    Not yet reported AHS Cancer Control Alberta 10 participants Est. completion 2027-12-01 1 site
    Other conditions: Glioblastoma, Recurrent Disease, Recurrent Glioblastoma
    View official trial listing →
  • Recruiting NCT NCT05436418

    The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

    Not yet reported, Not yet reported National Cancer Institute (NCI) 260 participants Est. completion 2028-06-25 2 sites Stand-alone
    Other conditions: Peripheral Blood Stem Cell Transplantation, Hematopoietic Stem Cell Transplantation
    View official trial listing →
  • Recruiting NCT NCT05444452

    GENOSS Coronary Stent Clinical Trial

    Not yet reported Samsung Medical Center 850 participants Est. completion 2027-06-30 1 site Stand-alone
    Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Recruiting NCT NCT05463133

    Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) Antagonists

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 50 participants Est. completion 2032-12-31 1 site Stand-alone
    Other conditions: Chronic Granulomatous Disease
    View official trial listing →
  • Recruiting NCT NCT05476939

    Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0

    Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 433 participants Est. completion 2031-09 53 sites
    Other conditions: Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, H3 K27M-Mutant, Diffuse Midline Glioma, H3K27-altered
    View official trial listing →
  • Recruiting NCT NCT05477576

    Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

    Not yet reported RayzeBio, Inc. 338 participants Est. completion 2030-12 54 sites
    Other conditions: GEP-NET, Gastroenteropancreatic Neuroendocrine Tumor, Gastroenteropancreatic Neuroendocrine Tumor Disease, Neuroendocrine Tumors, Carcinoid, Carcinoid Tumor, Pancreatic NET
    View official trial listing →
  • Recruiting NCT NCT05534672

    Placebo Controlled Study to Assess the Efficacy and Safety of Rapamycin in Drug Resistant Epilepsy Associated With Tuberous Sclerosis Complex

    Not yet reported Katarzyna Kotulska 200 participants Est. completion 2027-06 2 sites
    Other conditions: Tuberous Sclerosis Complex
    View official trial listing →
  • Recruiting NCT NCT05549167

    Efficacy and Safety of Sirolimus in Children and Adolescents With Juvenile Nasopharyngeal Angiofibroma (JNA)

    Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 117 participants Est. completion 2029-12-30 1 site Stand-alone
    Other conditions: Juvenile Nasopharyngeal Angiofibroma
    View official trial listing →
  • Recruiting NCT NCT05573126

    Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer

    Not yet reported, Not yet reported Ellipses Pharma 95 participants Est. completion 2028-02 14 sites
    Other conditions: Hormone Receptor-positive Breast Cancer, Hormone Receptor Positive HER-2 Negative Breast Cancer, Metastatic Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT05594095

    SNF Platform Study of HR+/ HER2-advanced Breast Cancer

    Not yet reported Fudan University 620 participants Est. completion 2026-12-01 1 site
    Other conditions: Breast Neoplasm, Breast Cancer, Hormone Receptor Positive Tumor, HER2-negative Breast Cancer, Advanced Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT05627960

    First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies

    Not yet reported A&G Pharmaceutical Inc. 77 participants Est. completion 2026-11 1 site
    Other conditions: Triple Negative Breast Cancer, Hormone-Resistant Breast Cancer, Non Small Cell Lung Cancer, Mesothelioma
    View official trial listing →
  • Recruiting NCT NCT05643872

    A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita

    Not yet reported Palvella Therapeutics, Inc. 45 participants Est. completion 2023-11 1 site
    Other conditions: Pachyonychia Congenita
    View official trial listing →
  • Recruiting NCT NCT05650411

    Ultrathin-strut Biodegradable Polymer Sirolimus-eluting Stents With P2Y12 Inhibitor-based Single Antiplatelet Therapy vs. Conventional DAPT for Unprotected Left Main Coronary Artery Disease (ULTIMATE-LM)

    Not yet reported IGLESIAS Juan Fernando 828 participants Est. completion 2032-05-01 1 site Stand-alone
    Other conditions: Left Main Coronary Artery Stenosis
    View official trial listing →
  • Recruiting NCT NCT05661461

    Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment

    Not yet reported Aadi Bioscience, Inc. 28 participants Est. completion 2026-08-01 2 sites Stand-alone
    Other conditions: Tumor, Solid, Tumor, Advanced Solid Tumor
    View official trial listing →
  • Recruiting NCT NCT05692882

    A Registry Study of Intracranial Atherosclerotic Stenosis Treatment by Intracranial Drug-eluting Stenting in China

    Not yet reported Sino Medical Sciences Technology Inc. 1000 participants Est. completion 2029-12-30 5 sites Stand-alone
    Other conditions: Intracranial Arteriosclerosis, Stenosis Artery, Drug-Eluting Stents, Intracranial Artery Stenosis
    View official trial listing →
  • Recruiting NCT NCT05725200

    Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer

    Not yet reported Oslo University Hospital 40 participants Est. completion 2040-12-31 1 site
    Other conditions: Metastatic Colorectal Cancer
    View official trial listing →
  • Recruiting NCT NCT05731687

    Bifurcation PCI With a Hybrid Strategy With Drug Eluting Balloons Versus a Stepwise Provisional Two-stent Strategy

    Not yet reported Cathreine BV 500 participants Est. completion 2030-03 1 site
    Cardiovascular disease Other conditions: Coronary Bifurcation Lesion
    View official trial listing →
  • Recruiting NCT NCT05749588

    FUSCC Refractory TNBC Platform Study (FUTURE2.0)

    Not yet reported Fudan University 120 participants Est. completion 2028-12-31 1 site
    Other conditions: Triple-negative Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT05773274

    Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial

    Not yet reported National Cancer Institute (NCI) 100 participants Est. completion 2029-04-30 40 sites
    Other conditions: Metastatic Digestive System Neuroendocrine Tumor G1, Metastatic Digestive System Neuroendocrine Tumor G2, Unresectable Digestive System Neuroendocrine Tumor G1, Unresectable Digestive System Neuroendocrine Tumor G2
    View official trial listing →
  • Recruiting NCT NCT05785897

    STEMI Treated With a Polymer-free Sirolimus-coated Stent and P2Y12 Inhibitor-based SAPT Versus Conventional DAPT

    Not yet reported IGLESIAS Juan Fernando 350 participants Est. completion 2028-03-01 2 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT05805605

    Allo HSCT Using RIC and PTCy for Hematological Diseases

    Not yet reported Masonic Cancer Center, University of Minnesota 56 participants Est. completion 2028-10-22 1 site Stand-alone
    Other conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Biphenotypic Acute Leukemia, Undifferentiated Leukemia, Prolymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Myelodysplastic Syndrome With Excess Blasts-1, Burkitt Lymphoma, Relapsed T-Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone Lymphoma, Follicular Lymphoma, Myeloproliferative Neoplasm, Myelofibrosis
    View official trial listing →
  • Recruiting NCT NCT05843253

    Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

    Not yet reported Nationwide Children's Hospital 120 participants Est. completion 2034-08-28 20 sites
    Other conditions: High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Anaplastic Astrocytoma, Glioblastoma, Glioblastoma Multiforme, Diffuse Midline Glioma, H3 K27M-Mutant, Metastatic Brain Tumor, WHO Grade III Glioma, WHO Grade IV Glioma, Diffuse Hemispheric Glioma, H3 G34-Mutant
    View official trial listing →
  • Recruiting NCT NCT05885932

    Drug-eluting Stenting Versus Medical Treatment for Extracranial Vertebral Artery Stenosis

    Not yet reported Xuanwu Hospital, Beijing 472 participants Est. completion 2028-09-01 1 site Stand-alone
    Cardiovascular disease Other conditions: Vertebral Artery Stenosis
    View official trial listing →
  • Recruiting NCT NCT05896839

    Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer

    Not yet reported, Not yet reported National Cancer Institute (NCI) 16 participants Est. completion 2027-01-31 26 sites Stand-alone
    Other conditions: Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8, Metastatic Basal Cell Carcinoma, Metastatic Carcinoma in the Skin, Metastatic Melanoma, Metastatic Merkel Cell Carcinoma, Metastatic Skin Squamous Cell Carcinoma, Unresectable Basal Cell Carcinoma, Unresectable Melanoma, Unresectable Merkel Cell Carcinoma, Unresectable Skin Squamous Cell Carcinoma
    View official trial listing →
  • Recruiting NCT NCT05908331

    MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions

    Not yet reported Concept Medical Inc. 492 participants Est. completion 2028-07 28 sites Stand-alone
    Cardiovascular disease Other conditions: In-Stent Restenosis
    View official trial listing →
  • Recruiting NCT NCT05918302

    Efficacy and Safety of Radiotherapy Compared to Everolimus in Somatostatin Receptor Positive Neuroendocrine Tumors of the Lung and Thymus.

    Not yet reported Grupo Espanol de Tumores Neuroendocrinos 170 participants Est. completion 2029-10 27 sites
    Other conditions: Neuroendocrine Tumors, Lung Neuroendocrine Neoplasm, Thymus Neoplasms
    View official trial listing →
  • Recruiting NCT NCT05925023

    Sirolimus in the Treatment of Refractory/Relapsed wAIHA

    Not yet reported Peking Union Medical College Hospital 22 participants Est. completion 2025-12 1 site Stand-alone
    Other conditions: Warm Autoimmune Hemolytic Anemia
    View official trial listing →
  • Recruiting NCT NCT05933395

    Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor

    Not yet reported Dartmouth-Hitchcock Medical Center 135 participants Est. completion 2031-10 1 site
    Other conditions: Advanced Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT05949541

    Efficacy of Everolimus Combined With First-line Endocrine Therapy for HR+/HER2- SNF1-subtype Advanced Breast Cancer

    Not yet reported Fudan University 265 participants Est. completion 2028-01 1 site
    Other conditions: Breast Cancer, Advanced Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT05949658

    Rapalog Pharmacology (RAP PAC) Study

    Not yet reported University of Wisconsin, Madison 72 participants Est. completion 2028-12 1 site Stand-alone
    Other conditions: Aging
    View official trial listing →
  • Recruiting NCT NCT05983107

    Chidamide/Everolimus for PIK3CA Wild-type/Mutant HR+/HER2- Advanced Breast Cancer

    Not yet reported Cancer Institute and Hospital, Chinese Academy of Medical Sciences 102 participants Est. completion 2027-07-15 1 site
    Other conditions: HR+/HER2- Advanced Breast Cancer, Targeted Therapy
    View official trial listing →
  • Recruiting NCT NCT05997017

    Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

    Not yet reported Aadi Bioscience, Inc. 29 participants Est. completion 2027-06 9 sites Stand-alone
    Other conditions: Endometrial Cancer, Endometrioid Tumor, Cancer, Tumor, Recurrent Endometrial Carcinoma, Endometrioid Endometrial Cancer
    View official trial listing →
  • Recruiting NCT NCT06018766

    LAM-001 in Lung Transplant Recipients With Bronchiolitis Obliterans Syndrome.

    Not yet reported Steven Hays, MD 30 participants Est. completion 2026-12 1 site
    Other conditions: Bronchiolitis Obliterans Syndrome, Chronic Lung Allograft Dysfunction, Lung Transplantation
    View official trial listing →
  • Recruiting NCT NCT06055608

    Advancing Transplantation Outcomes in Children

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 200 participants Est. completion 2028-06-30 21 sites Stand-alone
    Other conditions: Kidney Transplant
    View official trial listing →
  • Recruiting NCT NCT06065852

    National Registry of Rare Kidney Diseases

    UK Kidney Association 35000 participants Est. completion 2039-12-31 1 site
    Alcohol use disorder Other conditions: Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis, Alport Syndrome, Atypical Hemolytic Uremic Syndrome, Autoimmune Distal Renal Tubular Acidosis, Autosomal Recessive Proximal Renal Tubular Acidosis, Autosomal Recessive Distal Renal Tubular Acidosis, Autosomal Dominant Polycystic Kidney Disease, Autosomal Recessive Polycystic Kidney Disease, Bartter Syndrome, BK Nephropathy, C3 Glomerulopathy With Monoclonal Gammopathy, C3 Glomerulopathy, Calciphylaxis, Crystalglobulinaemia, Crystal-storing Histiocytosis, Cystinosis, Cystinuria, Dense Deposit Disease, Dent Disease, Denys-Drash Syndrome, Dominant Hypophosphataemia With Nephrolithiasis and/or Osteoporosis, Drug Induced Fanconi Syndrome, Drug-Induced Hypomagnesemia, Drug-Induced Nephrogenic Diabetes Insipidus, Epilepsy, Ataxia, Sensorineural Deafness and Tubulopathy, Fabry Disease, Familial Hypomagnesemia With Hypercalciuria and Nephrocalcinosis, Familial Primary Hypomagnesemia With Hypocalcuria, Familial Primary Hypomagnesaemia With Normocalciuria, Familial Renal Glucosuria, Fanconi Renotubular Syndrome 1, Fanconi Renotubular Syndrome 2, Fanconi Renotubular Syndrome 3, Fibrillary Glomerulonephritis, Fibromuscular Dysplasia, Focal Segmental Glomerulosclerosis, Generalised Pseudohypoaldosteronism Type 1, Gitelman Syndrome, Heavy-Metal-Induced Fanconi Syndrome, Hepatocyte Nuclear Factor 1-Beta-Associated Monogenic Diabetes, Hereditary Renal Hypouricemia, Hereditary Hypophosphatemic Rickets With Hypercalciuria, Hyperuricaemic Nephropathy, IgA Nephropathy, Immunotactoid Glomerulonephritis With Organised Microtubular Mononoclonal Immunoglobulin Deposits, Inherited Renal Cancer Syndromes, Intracapillary Monoclonal IgM Without Cryoglobulin, Intraglomerular/Capillary Lymphoma/Leukaemia, Liddle Syndrome, Light Chain Cast Nephropathy, Light Chain Proximal Tubulopathy Without Crystals, Light Chain Proximal Tubulopathy With Crystals, Lowe Syndrome, Membranous Nephropathy, Membranoproliferative Glomerulonephritis, Medullary Cystic Kidney Disease, Minimal Change Nephropathy, Mitochondrial Disease Of The Kidney, Monoclonal Immunoglobulin Deposition Disease, Nail Patella Syndrome, Nephrogenic Diabetes Insipidus, Nephrogenic Syndrome of Inappropriate Antidiuresis, Nephronophthisis, Primary Hypomagnesemia With Secondary Hypocalcemia, Primary Hyperoxaluria, Proliferative Glomerulonephritis With Monoclonal IgG Deposits, Proximal Tubulopathy Without Crystals, Pseudohypoaldosteronism Type 1, 2A-2E, Pure Red Cell Aplasia, Retroperitoneal Fibrosis, Sickle Cell Nephropathy, Shiga Toxin Associated Haemolytic Uraemic Syndrome, Steroid Resistant Nephrotic Syndrome, Steroid-Sensitive Nephrotic Syndrome, Thin Basement Membrane Nephropathy, Thrombotic Microangiopathy With Monoclonal Gammopathy, Type 1 Cryoglobulinaemic Glomerulonephritis, Tuberous Sclerosis, Unclassified Monoclonal Gammopathy Of Renal Significance, Vasculitis
    View official trial listing →
  • Recruiting NCT NCT06066450

    Efficacy of OSFIT Drug-Eluting Stent in Coronary Ostial Artery Stenosis

    Genoss Co., Ltd. 1000 participants Est. completion 2026-12-31 1 site
    Cardiovascular disease Other conditions: Drug-eluting Stent
    View official trial listing →
  • Recruiting NCT NCT06071429

    Bioresorbable Sirolimus-Eluting Scaffold Treatment for Below the Knee Disease

    Not yet reported R3 Vascular Inc. 300 participants Est. completion 2032-03-01 3 sites Stand-alone
    Other conditions: Chronic Limb-Threatening Ischemia
    View official trial listing →
  • Recruiting NCT NCT06075420

    Efficacy and Safety of Short Duration of DAPT After GENOSS® DES Implantation in Patients with Coronary Artery Disease

    Genoss Co., Ltd. 1000 participants Est. completion 2027-12-31 1 site
    Other conditions: Percutaneous Coronary Intervention, Dual Antiplatelet Therapy
    View official trial listing →
  • Recruiting NCT NCT06075433

    Efficacy and Safety of 1-year Duration of DAPT After GENOSS® DES Implantation in Patients with Coronary Artery Disease According to the Complex Higher-risk Procedure

    Genoss Co., Ltd. 1000 participants Est. completion 2027-12-31 1 site
    Cardiovascular disease Other conditions: Percutaneous Coronary Intervention, Dual Antiplatelet Therapy
    View official trial listing →
  • Recruiting NCT NCT06091332

    Hemorrhagic Brainstem Cavernous Malformations Treatment With Sirolimus: aSingle Centre, Randomized, Placebo-controlled Pilot Trial

    Not yet reported Huashan Hospital 75 participants Est. completion 2026-12-31 2 sites Stand-alone
    Cardiovascular disease Other conditions: Cavernous Malformations, Intracerebral Hemorrhage
    View official trial listing →
  • Recruiting NCT NCT06126588

    Combination of Everolimus and 177Lu-DOTATATE in the Treatment of Grades 2 and 3 Refractory Meningioma: a Phase IIb Clinical Trial

    Not yet reported Central Hospital, Nancy, France 28 participants Est. completion 2028-05-01 2 sites
    Other conditions: Meningioma
    View official trial listing →
  • Recruiting NCT NCT06182397

    Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

    Not yet reported Concept Medical Inc. 368 participants Est. completion 2031-02-01 29 sites
    Other conditions: Arterial Disease of Legs, Below-the-knee Obstruction, PAD - Peripheral Arterial Disease
    View official trial listing →
  • Recruiting NCT NCT06211790

    Proteomic Guided First-line Precision Treatment of Renal Clear Cell Carcinoma

    Not yet reported Fudan University 66 participants Est. completion 2026-12-30 1 site
    Other conditions: Kidney Cancer, Renal Cell Carcinoma, Renal Clear Cell Carcinoma
    View official trial listing →
  • Recruiting NCT NCT06236022

    The Effects of Sirolimus in Patients With Dilated Cardiomyopathy Infected With Kaposi Sarcoma-associated Virus

    Not yet reported Tongji Hospital 276 participants Est. completion 2028-12-31 1 site Stand-alone
    Other conditions: Dilated Cardiomyopathy, Kaposi's Sarcoma-Associated Herpesvirus Infection
    View official trial listing →
  • Recruiting NCT NCT06271590

    MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels

    Not yet reported Concept Medical Inc. 1605 participants Est. completion 2031-11 24 sites Stand-alone
    Cardiovascular disease Other conditions: Native Coronary Artery Stenosis
    View official trial listing →
  • Recruiting NCT NCT06280950

    Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 340 participants Est. completion 2030-06-30 12 sites
    Other conditions: Liver Transplant
    View official trial listing →
  • Recruiting NCT NCT06287944

    225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

    Not yet reported City of Hope Medical Center 15 participants Est. completion 2028-05-19 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome
    View official trial listing →
  • Recruiting NCT NCT06310291

    VTP-1000 in Adults With Celiac Disease

    Not yet reported Barinthus Biotherapeutics 45 participants Est. completion 2026-11 16 sites
    Other conditions: Celiac Disease
    View official trial listing →
  • Recruiting NCT NCT06325709

    Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 15 participants Est. completion 2032-12-31 1 site Stand-alone
    Other conditions: Chronic Granulomatous Disease (CGD), X-Linked Chronic Granulomatous Disease
    View official trial listing →
  • Recruiting NCT NCT06326190

    177Lu-DOTATATE for Recurrent Meningioma

    Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 136 participants Est. completion 2028-12-22 19 sites
    Other conditions: Recurrent Meningioma
    View official trial listing →
  • Recruiting NCT NCT06358638

    Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody

    Not yet reported Children's National Research Institute 12 participants Est. completion 2054-09 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Recruiting NCT NCT06373601

    SPAGO: Sirolimus Paclitaxel Angiographic Gain Objective

    Not yet reported Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS 140 participants Est. completion 2027-08-01 10 sites Stand-alone
    Cardiovascular disease Other conditions: Stenosis Coronary, Coronary Artery Lesion, Percutaneous Coronary Intervention
    View official trial listing →
  • Recruiting NCT NCT06382948

    Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i.

    Not yet reported MedSIR 300 participants Est. completion 2028-04 104 sites
    Other conditions: Advanced Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, ESR1 Gene Mutation
    View official trial listing →
  • Recruiting NCT NCT06412250

    A Multicenter Observational Registry to Evaluate Safety and Performance of Vivo ISAR (SECURE Global Registry)

    Translumina Therapeutics Pvt Ltd. 2000 participants Est. completion 2027-11 32 sites
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT06420505

    Evaluation of the Vivo Isar Stent System in Routine Clinical Practice

    Translumina GmbH 3000 participants Est. completion 2027-01-01 19 sites
    Other conditions: Artery Coronary Stenosis
    View official trial listing →
  • Recruiting NCT NCT06437574

    Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer

    Not yet reported Cedars-Sinai Medical Center 140 participants Est. completion 2028-05-31 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Recruiting NCT NCT06472388

    Everolimus 5 mg vs 10 mg/Daily for Patients With Neuroendocrine Tumors

    Not yet reported AC Camargo Cancer Center 100 participants Est. completion 2026-12-31 2 sites
    Other conditions: Neuroendocrine Tumors, Progression, Neuroendocrine Tumor Grade 1, Neuroendocrine Tumor Grade 2, Neuroendocrine Tumor of Pancreas, Neuroendocrine Tumor of the Lung, Neuroendocrine Tumor Carcinoid
    View official trial listing →
  • Recruiting NCT NCT06482086

    Efficacy of Organoid-Based Drug Screening to Guide Treatment for Locally Advanced Thyroid Cancer

    Not yet reported West China Hospital 75 participants Est. completion 2025-12-01 1 site
    Other conditions: Locally Advanced Thyroid Gland Carcinoma
    View official trial listing →
  • Recruiting NCT NCT06528301

    A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

    Not yet reported Umoja Biopharma 106 participants Est. completion 2029-03 8 sites
    Other conditions: Lymphoma, B-Cell, Lymphoma, Non-Hodgkin (NHL), Lymphoma, Large B-Cell, Diffuse (DLBCL), Chronic Lymphocytic Leukemia (CLL)
    View official trial listing →
  • Recruiting NCT NCT06551662

    DCB vs. DES in Bifurcation Coronary Lesions

    Not yet reported Fondazione Ricerca e Innovazione Cardiovascolare ETS 321 participants Est. completion 2028-02-01 17 sites Stand-alone
    Cardiovascular disease Other conditions: DCB
    View official trial listing →
  • Recruiting NCT NCT06552169

    REgulatory T Cell Therapy to Achieve Immunosuppression REduction

    Not yet reported Singulera Therapeutics Inc. 34 participants Est. completion 2031-12 7 sites Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Recruiting NCT NCT06618248

    Efficacy and Safety of Sirolimus-Coated Spiral Balloon for Coronary Bifurcation Lesions

    Not yet reported Dongguan TT Medical 280 participants Est. completion 2027-03 1 site Stand-alone
    Other conditions: Coronary Bifurcation Lesion
    View official trial listing →
  • Recruiting NCT NCT06658093

    RESTOR: PK/PD mTORi Inhibition in Older Adults

    Not yet reported The University of Texas Health Science Center at San Antonio 194 participants Est. completion 2028-07 1 site
    Other conditions: Aging
    View official trial listing →
  • Recruiting NCT NCT06663696

    CRUZ Tunisia-Multivessel Registry

    Sahajanand Medical Technologies Limited 1000 participants Est. completion 2028-05 2 sites
    Other conditions: Patient Population With Multivessel Disease
    View official trial listing →
  • Recruiting NCT NCT06673290

    Different Doses of Sirolimus for the Treatment of Cystic Lymphatic Malformations

    Not yet reported, Not yet reported West China Hospital 150 participants Est. completion 2026-12-30 1 site Stand-alone
    Other conditions: Lymphatic Malformation
    View official trial listing →
  • Recruiting NCT NCT06710210

    Hybrid Percutaneous Coronary Intervention Combining a Bioresorbable Scaffold With Drug-coated Balloons Versus a Conventional Drug-eluting Stent-based Strategy in Patients With Long and Diffuse Coronary Artery Disease

    Not yet reported University Hospital, Geneva 150 participants Est. completion 2028-04-01 4 sites Stand-alone
    Cardiovascular disease Other conditions: Percutaneous Coronary Intervention (PCI)
    View official trial listing →
  • Recruiting NCT NCT06719791

    Sirolomus Adjuvant Treatment of Focal Refractory Epilepsy (SATFRE)

    Not yet reported Xuanwu Hospital, Beijing 15 participants Est. completion 2028-12-01 1 site Stand-alone
    Other conditions: Epilepsy, Drug Resistant
    View official trial listing →
  • Recruiting NCT NCT06722586

    Sirolimus Monotherapy in the Treatment of Antiphospholipid Antibody Related Thrombocytopenia

    Not yet reported Peking University First Hospital 84 participants Est. completion 2027-12 10 sites Stand-alone
    Other conditions: Antiphospholipid (aPL)-Positive, Thrombocytopaenia
    View official trial listing →
  • Recruiting NCT NCT06727305

    MTOR Inhibitors in Older Adults

    Not yet reported, Not yet reported University of Texas Southwestern Medical Center 60 participants Est. completion 2027-11-13 1 site
    Other conditions: Aging
    View official trial listing →
  • Recruiting NCT NCT06743503

    UB-VV400 in Combination With Rapamycin in Relapsed or Refractory B-cell Malignancies

    Not yet reported Nanjing IASO Biotechnology Co., Ltd. 70 participants Est. completion 2030-07-31 2 sites
    Other conditions: Large B-cell Lymphoma
    View official trial listing →
  • Recruiting NCT NCT06779630

    Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

    Not yet reported Teleflex 150 participants Est. completion 2031-09 23 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT06799195

    Optimizing GVHD Prophylaxis After Allogeneic Hematopoietic Cell Transplantation

    Not yet reported University of Nebraska 126 participants Est. completion 2031-11 1 site Stand-alone
    Other conditions: Hematological Malignancies, Graft-versus-Host Disease (GVHD)
    View official trial listing →
  • Recruiting NCT NCT06802055

    Efficacy and Safety of Sirolimus With or Without Cyclosporin A in Chinese Patients With Aplastic Anemia Refractory/Intolerant to Cyclosporin A

    Not yet reported Peking Union Medical College Hospital 40 participants Est. completion 2027-01 1 site Stand-alone
    Other conditions: Aplastic Anaemia
    View official trial listing →
  • Recruiting NCT NCT06822712

    Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for De Novo Coronary Bifurcation Lesions

    Not yet reported BrosMed Medical Co., Ltd 250 participants Est. completion 2026-06 1 site Stand-alone
    Other conditions: Coronary Arterial Disease (CAD)
    View official trial listing →
  • Recruiting NCT NCT06832189

    EVR and EPO for Liver Transplant Tolerance

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 20 participants Est. completion 2030-06-01 3 sites
    Other conditions: Liver Transplant
    View official trial listing →
  • Recruiting NCT NCT06856200

    A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast Cancer

    Not yet reported Fudan University 36 participants Est. completion 2026-06 1 site Stand-alone
    Other conditions: Advanced HR - Positive, HER2 - Negative Breast Cancer, Resistant to (Neo)Adjuvant Endocrine Therapy
    View official trial listing →
  • Recruiting NCT NCT06857058

    Standardized Procedure for Intracranial Drug-Eluting Stenting in the Treatment of Intracranial Atherosclerotic Stenosis

    Not yet reported Sino Medical Sciences Technology Inc. 300 participants Est. completion 2026-06-08 1 site Stand-alone
    Other conditions: Intracranial Atherosclerotic Stenosis
    View official trial listing →
  • Recruiting NCT NCT06863155

    Ultrathin Strut Sirolimus-eluting Stent With Bioabsorbable Polymer in Patients Receiving Chronic Oral Anticoagulation

    Fundación EPIC 500 participants Est. completion 2029-03-31 13 sites
    Cardiovascular disease Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Recruiting NCT NCT06866756

    Experience in Percutaneous Coronary Intervention With Sirolimus Drug-Coated Balloon and Paclitaxel Drug-Coated Balloon

    Andres Iñiguez Romo 479 participants Est. completion 2026-12-31 1 site
    Other conditions: Coronary Arterial Disease (CAD)
    View official trial listing →
  • Recruiting NCT NCT06872333

    Allo HSCT for High Risk Hemoglobinopathies

    Not yet reported Masonic Cancer Center, University of Minnesota 62 participants Est. completion 2032-06-01 1 site Stand-alone
    Other conditions: Graft Failure, Sickle Cell Disease, Hemoglobinopathies
    View official trial listing →
  • Recruiting NCT NCT06881927

    Eduction in ImmunoSuppressive Regimen Among Kidney Transplant Recipients Patients Admitted to the Intensive Care Unit for Septic Shock and/or Acute Respiratory Failure

    Not yet reported University Hospital, Strasbourg, France 212 participants Est. completion 2029-08-01 1 site
    Other conditions: Sepsis and Septic Shock, Acute Respiratory Failure, Kidney Transplant Recipients, Immunosuppressive Agents
    View official trial listing →
  • Recruiting NCT NCT06943755

    Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

    Not yet reported, Not yet reported Exelixis 440 participants Est. completion 2029-06-30 131 sites
    Other conditions: Pancreatic Neuroendocrine Tumor (pNET), Extra-Pancreatic Neuroendocrine Tumor (epNET)
    View official trial listing →
  • Recruiting NCT NCT06950385

    Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

    Not yet reported Rapamycin Holdings Inc. 168 participants Est. completion 2031-01 29 sites
    Other conditions: Familial Adenomatous Polyposis (FAP)
    View official trial listing →
  • Recruiting NCT NCT06955169

    Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior Treatment

    Not yet reported RTOG Foundation, Inc. 130 participants Est. completion 2030-08 16 sites
    Other conditions: Intracranial Meningioma
    View official trial listing →
  • Recruiting NCT NCT06959771

    Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient Study

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 1 participants Est. completion 2027-10-28 1 site Stand-alone
    Other conditions: CD40L-HyperIgM Syndrome
    View official trial listing →
  • Recruiting NCT NCT06960928

    Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19

    Not yet reported Icahn School of Medicine at Mount Sinai 80 participants Est. completion 2027-05-31 1 site Stand-alone
    Other conditions: Long COVID-19
    View official trial listing →
  • Recruiting NCT NCT06973668

    A Randomized Study to Compare Post-transplant Cyclophosphamide, Sirolimus, Ruxolitinib and Post-transplant Cyclophosphamide, Sirolimus, Mycophenolate Mofetil to Prevent Graft Versus Host Disease

    Not yet reported M.D. Anderson Cancer Center 80 participants Est. completion 2030-01-31 1 site Stand-alone
    Other conditions: AML
    View official trial listing →
  • Recruiting NCT NCT07002177

    A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC

    Not yet reported, Not yet reported Forward Pharmaceuticals Co., Ltd. 196 participants Est. completion 2028-11-01 1 site
    Other conditions: Metastatic Breast Cancer, Breast Cancer Stage I, Breast Cancer Stage II, Locally Advanced Breast Cancer (LABC), ER+ Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT07004569

    Angiolite Registry Study

    Chinese University of Hong Kong 55 participants Est. completion 2025-07-28 1 site
    Other conditions: With Left Main Coronary Artery Lesions
    View official trial listing →
  • Recruiting NCT NCT07015684

    131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD)

    Not yet reported Columbia University 24 participants Est. completion 2032-03-12 1 site Stand-alone
    Other conditions: Sickling Disorder Due to Hemoglobin S
    View official trial listing →
  • Recruiting NCT NCT07022587

    Bioresorbable Sirolimus-eluting scaffold in de Novo Coronary Artery Lesions

    Not yet reported Xijing Hospital 2000 participants Est. completion 2073-12-20 1 site Stand-alone
    Cardiovascular disease Other conditions: De Novo Stenosis
    View official trial listing →
  • Recruiting NCT NCT07024173

    A Phase 3 Study of HRS-8080 Versus Treatment Chosen by Physicians in Locally Advanced and Metastatic Breast Cancer

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 240 participants Est. completion 2027-12 2 sites
    Other conditions: Locally Advanced Breast Cancer, Metastatic Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT07033858

    Evaluaion the Short Term Effects of Advograf Plus Rapamiune After Kidney Transplantation

    Not yet reported Shahid Beheshti University of Medical Sciences 50 participants Est. completion 2026-07-01 1 site
    Other conditions: Kidney Transplant; Complications
    View official trial listing →
  • Recruiting NCT NCT07037238

    An Open-Label, Single-Arm Exploratory Clinical Study of Everolimus for the Treatment of Vascular Malformations

    Not yet reported Xuanwu Hospital, Beijing 10 participants Est. completion 2026-12-31 1 site
    Other conditions: Vascular Malformations
    View official trial listing →
  • Recruiting NCT NCT07045194

    Virtue® SAB in the Treatment of Coronary ISR Trial

    Not yet reported Orchestra BioMed, Inc 740 participants Est. completion 2032-10 15 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT07052929

    Study of ASP2957 in Male Participants With X-linked Myotubular Myopathy Who Need Ventilators

    Not yet reported, Not yet reported Astellas Gene Therapies 9 participants Est. completion 2027-10-31 5 sites Stand-alone
    Other conditions: X-Linked Myotubular Myopathy
    View official trial listing →
  • Recruiting NCT NCT07062965

    A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.

    Not yet reported Pfizer 400 participants Est. completion 2030-11-04 202 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT07077486

    Effects of Telitacicept vs Cyclophosphamide on Lupus Related Interstitial Lung Disease

    Not yet reported Tongji Hospital 100 participants Est. completion 2027-03-25 1 site Stand-alone
    Other conditions: Lupus or SLE, Interstitial Lung Disease, Systemic Lupus Erythematosus
    View official trial listing →
  • Recruiting NCT NCT07091682

    Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold System in the Treatment of Subjects With Long de Novo Lesions

    Not yet reported Biotronik AG 100 participants Est. completion 2031-06 14 sites Stand-alone
    Cardiovascular disease Other conditions: Atherosclerosis of Coronary Artery, Myocardial Ischemia, Ischemic Heart Disease, Acute Coronary Syndromes, Angina Pectoris
    View official trial listing →
  • Recruiting NCT NCT07092618

    Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation

    Not yet reported, Not yet reported AgelessRx 150 participants Est. completion 2025-08 1 site
    Other conditions: Longevity, GLP-1, Geroscience, Aging
    View official trial listing →
  • Recruiting NCT NCT07095933

    The Safety and Efficacy Evaluation of Everolimus as an Adjunctive Treatment for Focal Refractory Epilepsy

    Not yet reported Xuanwu Hospital, Beijing 5 participants Est. completion 2026-12-31 1 site
    Other conditions: Epilepsy, Drug Resistant
    View official trial listing →
  • Recruiting NCT NCT07104331

    SARC046: A Phase II Trial of Nab-Sirolimus in Patients With Progressing or Symptomatic Epithelioid Hemangioendothelioma

    Not yet reported Sarcoma Alliance for Research through Collaboration 41 participants Est. completion 2029-08-30 6 sites Stand-alone
    Other conditions: Epithelioid Hemangioendothelioma (EHE)
    View official trial listing →
  • Recruiting NCT NCT07122167

    Post-market Registry Study on the Safety and Efficacy of ZENFLEX Pro™ Peripheral Drug-eluting Stent System for Femoropopliteal Artery Lesions

    Not yet reported MDCECRO LLC 153 participants Est. completion 2027-02-01 1 site
    Other conditions: Peripheral Arterial Disease
    View official trial listing →
  • Recruiting NCT NCT07124078

    A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

    Not yet reported Incyte Corporation 60 participants Est. completion 2029-07-31 41 sites
    Other conditions: Chronic Graft-versus-host-disease
    View official trial listing →
  • Recruiting NCT NCT07131644

    Sirolimus Discontinuation Strategies in Kaposiform Hemangioendothelioma

    Not yet reported West China Hospital 120 participants Est. completion 2028-02-01 1 site Stand-alone
    Other conditions: Kaposiform Hemangioendothelioma
    View official trial listing →
  • Recruiting NCT NCT07144150

    EVERO Drug-coated Balloon (DCB) Randomized Trial

    Not yet reported Cook Research Incorporated 410 participants Est. completion 2032-10 11 sites
    Other conditions: Peripheral Vascular Disease, Peripheral Arterial Disease
    View official trial listing →
  • Recruiting NCT NCT07162038

    Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation

    Not yet reported National Cancer Institute (NCI) 155 participants Est. completion 2034-10-01 1 site Stand-alone
    Other conditions: Hematologic Malignancies, Hematologic Neoplasms
    View official trial listing →
  • Recruiting NCT NCT07165886

    Sirolimus for Injection (Albumin Bound) Combined With Octreotide Long-acting Injection in Patients With Metastatic Gastroenteropancreatic Neuroendocrine Tumors

    Not yet reported, Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 298 participants Est. completion 2028-08-29 1 site Stand-alone
    Other conditions: Gastroenteropancreatic Neuroendocrine Tumors
    View official trial listing →
  • Recruiting NCT NCT07173114

    New Approaches for Evaluating the Interchangeability of Reference Materials and Quality Controls (COMET-MPL)

    University Hospital, Montpellier 300 participants Est. completion 2026-09-22 2 sites
    Other conditions: Hospitalization, All Conditions
    View official trial listing →
  • Recruiting NCT NCT07190690

    Comparison of a Contemporary Sirolimus-eluting Stent (ihtDEStiny®) With Another Everolimus-eluting Stent (Xience™), Both With Permanent Polymers, in Patients With Acute Coronary Syndrome and de Novo Coronary Artery Lesions

    Not yet reported Fundación EPIC 2100 participants Est. completion 2030-10-15 20 sites
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT07191353

    Resistance Training and Rapamycin to Enhance Bone Formation in Postmenopausal Women

    Not yet reported Odense University Hospital 148 participants Est. completion 2027-03-01 2 sites
    Other conditions: Healthy, Osteopenia, Osteoporosis Risk
    View official trial listing →
  • Recruiting NCT NCT07241936

    A Study of Sirolimus (Albumin-Bound) in Combination With Different ADCs Treatment of Advanced Solid Tumors

    Not yet reported, Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 444 participants Est. completion 2028-10-30 1 site Stand-alone
    Other conditions: Advanced Solid Tumors
    View official trial listing →
  • Recruiting NCT NCT07252050

    Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease

    Not yet reported, Not yet reported Arkansas Children's Hospital Research Institute 24 participants Est. completion 2029-11-19 4 sites Stand-alone
    Other conditions: Sickle Cell Disease, Hematopoetic Stem Cell Transplant, Haploidentical Hematopoietic Stem Cell Transplant, Haploidentical Stem Cell Transplantation, Graft Failure
    View official trial listing →
  • Recruiting NCT NCT07256249

    Real-life Registry in Patients With Coronary Artery Disease Treated With the SELUTION Sirolimus-eluting Balloon. Selution Iberia Registry

    Fundación EPIC 960 participants Est. completion 2027-01-01 14 sites
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT07258290

    Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold (RMS) System in Subjects With Coronary Artery Lesions

    Not yet reported Teleflex 1859 participants Est. completion 2033-06 3 sites Stand-alone
    Cardiovascular disease Other conditions: Coronary Disease, Heart Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases, Chest Pain, Pain, Neurologic Manifestations, Signs and Symptoms, Pathological Conditions, Signs and Symptoms, Myocardial Ischemia, Acute Coronary Syndrome, Angina Pectoris
    View official trial listing →
  • Recruiting NCT NCT07270549

    Gene Replacement Therapy for Treatment of Paediatric Patients With CTNNB1 Neurodevelopmental Syndrome

    Not yet reported, Not yet reported CTNNB1 Foundation 12 participants Est. completion 2032-12-31 1 site Stand-alone
    Other conditions: CTNNB1 Neurodevelopmental Syndrome
    View official trial listing →
  • Recruiting NCT NCT07318324

    Phase Ib Study of Avutometinib, Defactinib, and Everolimus in RAS Pathway Mutant Endometrial Cancer

    Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2030-08-01 1 site
    Other conditions: Phase IB, Avutometinib, RAS Pathway, Endometrial
    View official trial listing →
  • Recruiting NCT NCT07340541

    Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies

    Not yet reported UNC Lineberger Comprehensive Cancer Center 700 participants Est. completion 2031-06-02 6 sites
    Other conditions: Breast Cancer, Metastatic Breast Cancer, Triple Negative Breast Cancer, Estrogen-receptor-positive Breast Cancer, Hormone Receptor Negative Breast Carcinoma
    View official trial listing →
  • Recruiting NCT NCT07352852

    Rapamycin-Eluting Vertebral Stents In The Real-World Treatment of Symptomatic Intracranial Atherosclerotic Stenosis

    The Affiliated Hospital of Qingdao University 300 participants Est. completion 2028-12-31 1 site
    Other conditions: Intracranial Arterial Stenosis, Brain Diseases
    View official trial listing →
  • Recruiting NCT NCT07363161

    BASel Kosten-Effektivitäts-Trial: Drug-coated BALLoon (DCB) vs. Drug-eluting Stent (DES) Strategy in High-risk Patients With Coronary Artery Disease (CAD)

    Not yet reported B. Braun Melsungen AG 2184 participants Est. completion 2031-03 3 sites
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT07366801

    Co-infusion of Treg-enriched Donor Lymphocytes With CD3-depleted Hematopoietic Stem Cell Graft to Prevent Graft-versus Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation Among Children With Hematologic Malignancies

    Not yet reported, Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 64 participants Est. completion 2028-02-03 1 site
    Other conditions: Acute Myeloid Leukemia, Relapsed, Acute Lymphoblastic Leukemia, High Risk, Acute Myeloid Leukemia, High Risk, Acute Lymphoblastic Leukemia, Relapse
    View official trial listing →
  • Recruiting NCT NCT07369505

    Sapu003 in Advanced mTOR-sensitive Solid Tumors

    Not yet reported SAPU NANO (US) LLC 27 participants Est. completion 2026-12 1 site
    Other conditions: Breast Cancer Metastatic, Renal Cell Carcinoma (RCC), Neuroendocrine Tumors, Tuberous Sclerosis Complex (TSC), Hepatocellular Carcinoma (HCC)
    View official trial listing →
  • Recruiting NCT NCT07378657

    Systematic Approach for Children With Orbital Malformation With Sirolimus Use

    Not yet reported Ain Shams University 30 participants Est. completion 2027-11-01 1 site
    Other conditions: Orbital Lymphatic Malformation
    View official trial listing →
  • Recruiting NCT NCT07426484

    Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy

    Not yet reported Dana-Farber Cancer Institute 80 participants Est. completion 2032-12-15 2 sites Stand-alone
    Other conditions: Cutaneous Squamous Cell Carcinoma, Skin Cancer
    View official trial listing →
  • Recruiting NCT NCT07443826

    CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy

    Not yet reported, Not yet reported Unlimited Biotechnology LLC 12 participants Est. completion 2028-06-30 1 site
    Other conditions: Age-related Muscle Decline
    View official trial listing →
  • Recruiting NCT NCT07444957

    Safety and Effectiveness of the Crystalline Sirolimus-Eluting Device in Patients With Coronary Artery Disease

    Fundación Interhospitalaria para la Investigación Cardiovascular FIC 1118 participants Est. completion 2030-07-06 1 site
    Cardiovascular disease Other conditions: Coronary Arterial Disease (CAD), Stable Angina, Unstable Angina, NSTEMI, Drug Coated Balloon, Silent Ischemia
    View official trial listing →
  • Recruiting NCT NCT07463664

    Clinical Outcomes of Drug-Coated Balloons in the Treatment of Patients With Coronary De Novo Chronic Total Occlusion Lesions

    Not yet reported The First Affiliated Hospital of Zhengzhou University 200 participants Est. completion 2026-12-31 18 sites Stand-alone
    Cardiovascular disease Other conditions: Chronic Total Occlusions of Coronary Arteries, Chronic Total Occlusion (CTO)
    View official trial listing →
  • Recruiting NCT NCT07542938

    Medeliver Intracranial Drug Coated Balloon Catheter for Symptomatic Intracranial Atherosclerotic Stenosis

    Not yet reported Xuanwu Hospital, Beijing 264 participants Est. completion 2027-11-30 15 sites Stand-alone
    Other conditions: Symptomatic Intracranial Atherosclerotic Stenosis
    View official trial listing →
  • Recruiting NCT NCT07552077

    A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Angiokeratomas (LOTU)

    Not yet reported Palvella Therapeutics, Inc. 15 participants Est. completion 2027-09 4 sites
    Other conditions: Angiokeratomas
    View official trial listing →
  • Recruiting NCT NCT07582172

    Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

    Not yet reported City of Hope Medical Center 35 participants Est. completion 2029-04-05 1 site Stand-alone
    Other conditions: Acute Myeloid Leukemia With Complex Karyotype, Myelodysplastic Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Chronic Myelomonocytic Leukemia, Recurrent Myelodysplastic Syndrome, Recurrent Secondary Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic Chronic Myelomonocytic Leukemia, Refractory Myelodysplastic Syndrome, Refractory Secondary Acute Myeloid Leukemia
    View official trial listing →
  • Recruiting NCT NCT07587099

    Single vs. Dual Antiplatelet Therapy in Patients Undergoing Percutaneous Intervention With DCB-only Strategy (KONG-FREEDOM-I)

    Not yet reported Gan Lijun 2170 participants Est. completion 2030-12-31 14 sites
    Other conditions: Coronary Heart Disease (CHD)
    View official trial listing →
  • Recruiting NCT NCT07616154

    Haploidentical Donor Hematopoietic Cell Transplant for Sickle Cell Disease

    Not yet reported St. Jude Children's Research Hospital 45 participants Est. completion 2035-09 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Recruiting NCT NCT07646171

    EVERST- Everolimus After Alpelisib in Women With Hormone Receptor-positive (HR+) Metastatic Breast Cancer (MBC)

    Tel-Aviv Sourasky Medical Center 19 participants Est. completion 2027-12-31 1 site
    Other conditions: Hormone Receptor Positive Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT07656909

    Low- vs High-Dose Sirolimus With Prednisolone for KHE and KMP

    Not yet reported, Not yet reported Yi Ji 76 participants Est. completion 2028-12-31 1 site Stand-alone
    Other conditions: Kaposiform Hemangioendothelioma (KHE), Kasabach Merritt Phenomenon
    View official trial listing →
  • Recruiting NCT NCT07657793

    Sirolimus in Patients With Systemic Lupus Erythematosus-Associated Immune Thrombocytopenia

    Not yet reported, Not yet reported Chinese SLE Treatment And Research Group 164 participants Est. completion 2029-09-30 1 site Stand-alone
    Other conditions: Systemic Lupus Erythematosus, Immune Thrombocytopenia
    View official trial listing →
  • Recruiting NCT NCT07725380

    Domatinostat With Sirolimus for Relapsed, Refractory Sarcoma and Osteosarcoma

    Not yet reported, Not yet reported H. Lee Moffitt Cancer Center and Research Institute 74 participants Est. completion 2031-08 4 sites Stand-alone
    Obstructive sleep apnea Other conditions: Sarcoma
    View official trial listing →
  • Recruiting NCT NCT07806370

    A Single-Center, Retrospective, Propensity-Score-Matched Cohort Study Comparing Drug-Coated Balloon Versus Drug-Eluting Stent for Reducing Immediate Post-Procedural Slow-Flow/No-Reflow in Acute ST-Elevation Myocardial Infarction Patients With High Thrombus Burden

    Xijing Hospital 668 participants Est. completion 2028-01-31 1 site
    Cardiovascular disease Other conditions: Acute Coronary Syndromes (ACS)
    View official trial listing →
  • Recruiting NCT NCT07811024

    First-in-Human Study Using the SiroMax™ Sirolimus-Coated Balloon Catheter as a Percutaneous Transluminal Coronary Angioplasty (PTCA) Balloon Catheter to Treat Subjects Who Have Coronary Artery Disease (CAD) Involving In-Stent Restenosis (ISR) or an Unstented Lesion in a Small Coronary Vessel (DNSV).

    Not yet reported Tonic Medical, Inc. 60 participants Est. completion 2032-05 2 sites Stand-alone
    Cardiovascular disease Other conditions: In-Stent Restenosis or De Novo Coronary Artery Lesions, In-Stent Stenosis (Restenosis) of Coronary Artery Stent, Small Vessel Disease, CAD, CAD Patients, PTCA, PCI, Stenosis Coronary, Stenosis Artery, Stenotic Coronary Lesion
    View official trial listing →
  • Recruiting NCT NCT07844694

    Low-Dose Sirolimus for the Treatment of RUNX1 Familial Platelet Disorder

    Not yet reported OHSU Knight Cancer Institute 6 participants Est. completion 2030-12-31 1 site Stand-alone
    Other conditions: Familial Platelet Disorder With Associated Myeloid Malignancy
    View official trial listing →
  • Completed NCT NCT00001247

    Inpatient Evaluation of Adults With Schizophrenia

    National Institute of Mental Health (NIMH) 648 participants 1 site
    Other conditions: Schizophrenia
    View official trial listing →
  • Withdrawn NCT NCT00002790

    Prevention of Graft-Versus-Host Disease in Patients With Hematologic Malignancies Who Are Receiving a Bone Marrow Transplant

    Not yet reported, Not yet reported Fred Hutchinson Cancer Center
    Other conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00003712

    CCI-779 in Treating Patients With Advanced Solid Tumors

    Not yet reported The University of Texas Health Science Center at San Antonio 15 participants Est. completion 2002-06 2 sites
    Other conditions: Brain and Central Nervous System Tumors, Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Terminated NCT NCT00005113

    A Study to Compare Treatment With Sirolimus Versus Standard Treatment in Patients Who Have Received a Kidney Transplant

    Not yet reported Boston Children's Hospital 102 participants Est. completion 2006-03 1 site Stand-alone
    Other conditions: End-Stage Renal Disease, Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00006178

    Sirolimus and Thymoglobulin to Prevent Kidney Transplant Rejection

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 12 participants Est. completion 2007-12 1 site Stand-alone
    Other conditions: Kidney Failure
    View official trial listing →
  • Completed NCT NCT00012142

    CCI-779 in Treating Patients With Prostate Cancer

    Not yet reported Jonsson Comprehensive Cancer Center Est. completion 2004-03 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00014911

    Islet Transplantation for Type 1 Diabetes

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 36 participants Est. completion 2010-08 9 sites Stand-alone
    Other conditions: Diabetes Mellitus, Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00016328

    CCI-779 in Treating Patients With Recurrent Glioblastoma Multiforme

    Not yet reported National Cancer Institute (NCI) 33 participants 1 site
    Obstructive sleep apnea Other conditions: Adult Giant Cell Glioblastoma, Adult Glioblastoma, Recurrent Adult Brain Tumor
    View official trial listing →
  • Completed NCT NCT00022464

    CCI-779 in Treating Patients With Metastatic Melanoma

    Not yet reported City of Hope Medical Center Est. completion 2005-09 21 sites
    Other conditions: Melanoma (Skin)
    View official trial listing →
  • Completed NCT NCT00022724

    CCI-779 in Treating Patients With Malignant Glioma

    Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 49 participants Est. completion 2007-12-15 10 sites
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Completed NCT NCT00023231

    Pediatric Kidney Transplant Without Calcineurin Inhibitors

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 35 participants Est. completion 2006-08 1 site Stand-alone
    Other conditions: End-Stage Renal Disease
    View official trial listing →
  • Terminated NCT NCT00023244

    Steroid Withdrawal in Pediatric Kidney Transplant Recipients

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 274 participants Est. completion 2005-06 19 sites Stand-alone
    Other conditions: End-Stage Renal Disease
    View official trial listing →
  • Completed NCT NCT00028028

    CCI-779 in Treating Patients With Extensive-Stage Small Cell Lung Cancer

    Not yet reported National Cancer Institute (NCI) 80 participants 1 site
    Other conditions: Extensive Stage Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT00033267

    CCI-779 in Treating Patients With Mantle Cell Non-Hodgkin's Lymphoma

    Not yet reported National Cancer Institute (NCI) 27 participants Est. completion 2008-02 1 site
    Other conditions: Recurrent Mantle Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT00037531

    Study Evaluating Sirolimus (Rapamune™) in Solid Organ Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 769 participants Est. completion 2004-08 20 sites
    Other conditions: Graft vs Host Disease, Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00038948

    Study Comparing Conversion to Sirolimus vs. Continued Use of Calcineurin Inhibitors in Kidney Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 830 participants Est. completion 2008-05
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00040508

    Sirolimus for Focal Segmental Glomerulosclerosis

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 30 participants Est. completion 2005-01 1 site
    Other conditions: Focal Glomerulosclerosis
    View official trial listing →
  • Completed NCT NCT00043979

    Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas

    Not yet reported National Cancer Institute (NCI) 60 participants Est. completion 2011-12-14 1 site Stand-alone
    Other conditions: Sarcoma
    View official trial listing →
  • Completed NCT NCT00044720

    Study Evaluating Sirolimus in End Stage Renal Disease in High Risk Kidney Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 484 participants Est. completion 2005-07
    Other conditions: Chronic Kidney Failure, Graft vs Host Disease, Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00045370

    Chemotherapy and Biological Therapy in Treating Patients With Locally Advanced or Metastatic Kidney Cancer

    Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2003-11 1 site
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT00047073

    Sirolimus in Treating Patients With Glioblastoma Multiforme

    Not yet reported, Not yet reported Jonsson Comprehensive Cancer Center 13 participants Est. completion 2007-10 1 site
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Completed NCT NCT00050713

    Sirolimus Therapy for Idiopathic and Lupus Membranous Nephropathy

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 12 participants Est. completion 2007-08-27 1 site
    Other conditions: Membranous Glomerulonephritis, Lupus Membranous Nepropathy
    View official trial listing →
  • Completed NCT NCT00060632

    Safety Study of Ridaforolimus in Patients With Advanced, Refractory or Recurrent Malignancies (MK-8669-001 AM5)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 46 participants Est. completion 2005-10
    Other conditions: Tumors, Lymphoma, Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00060645

    Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 33 participants Est. completion 2009-02 1 site
    Other conditions: Tumors, Lymphoma, Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00061360

    Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia

    Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 77 participants Est. completion 2015-09-08 1 site
    Other conditions: Severe Aplastic Anemia
    View official trial listing →
  • Active, not recruiting NCT NCT00061568

    Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias

    Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 130 participants Est. completion 2028-01-20 1 site Stand-alone
    Other conditions: Congenital Hemolytic Anemia, Sickle Cell Disease
    View official trial listing →
  • Completed NCT NCT00062712

    Evaluating the Use of Thymoglobulin, Sirolimus, and Donor Bone Marrow With Kidney Transplantation Patients

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 20 participants Est. completion 2007-03-22 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00062751

    Study Evaluating Temsirolimus (CCI-779) In Breast Neoplasms

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 108 participants Est. completion 2009-10
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Completed NCT NCT00065468

    Study Evaluating Interferon And CCI-779 In Advanced Renal Cell Carcinoma

    Not yet reported Pfizer 626 participants Est. completion 2011-03 153 sites
    Other conditions: Carcinoma, Renal Cell, Kidney Neoplasms
    View official trial listing →
  • Completed NCT NCT00071968

    Neoadjuvant CCI-779 Followed By Radical Prostatectomy in Treating Patients With Newly Diagnosed Prostate Cancer Who Have a High Risk of Relapse

    Not yet reported Jonsson Comprehensive Cancer Center 15 participants 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00072176

    Temsirolimus in Treating Patients With Metastatic or Locally Advanced Recurrent Endometrial Cancer

    Not yet reported National Cancer Institute (NCI) 62 participants Est. completion 2009-08 1 site
    Other conditions: Endometrial Adenocarcinoma, Endometrial Adenosquamous Cell Carcinoma, Endometrial Clear Cell Carcinoma, Endometrial Papillary Serous Carcinoma, Recurrent Endometrial Carcinoma, Stage IIIA Endometrial Carcinoma, Stage IIIB Endometrial Carcinoma, Stage IIIC Endometrial Carcinoma, Stage IVA Endometrial Carcinoma, Stage IVB Endometrial Carcinoma
    View official trial listing →
  • Terminated NCT NCT00074490

    Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers

    Not yet reported National Cancer Institute (NCI) 442 participants Est. completion 2017-08-16 2 sites Stand-alone
    Other conditions: Lymphoma, Leukemia, Myeloproliferative Disorders, Multiple Myleoma, Myelodysplastic Syndrome
    View official trial listing →
  • Completed NCT NCT00075647

    CCI-779 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer

    Not yet reported National Cancer Institute (NCI) 40 participants 1 site
    Other conditions: Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage II Pancreatic Cancer, Stage III Pancreatic Cancer, Stage IV Pancreatic Cancer
    View official trial listing →
  • Terminated NCT NCT00076206

    Study Evaluating CCI-779 in Active Rheumatoid Arthritis on Concomitant Methotrexate Therapy

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer Est. completion 2005-08
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00076570

    Combination Drug Therapy Followed by Single Drug Steroid Free Therapy to Prevent Organ Rejection in Kidney Transplantation

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 31 participants Est. completion 2012-08 1 site Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00078559

    Combination Immunosuppressive Therapy to Prevent Kidney Transplant Rejection in Adults

    Not yet reported, Not yet reported University of Wisconsin, Madison 10 participants Est. completion 2010-02 1 site Stand-alone
    Other conditions: Kidney Transplantation, Kidney Disease
    View official trial listing →
  • Completed NCT NCT00078689

    Daclizumab and Sirolimus to Treat Uveitis

    Not yet reported National Eye Institute (NEI) 6 participants Est. completion 2008-07-18 1 site
    Other conditions: Uveitis
    View official trial listing →
  • Completed NCT NCT00079183

    Sirolimus as Secondary Therapy in Chronic Graft-Versus-Host Disease Not Responding To Prior Treatment

    Not yet reported Fred Hutchinson Cancer Center 44 participants Est. completion 2010-06-10 1 site Stand-alone
    Other conditions: Graft Versus Host Disease
    View official trial listing →
  • Completed NCT NCT00079235

    CCI-779 in Treating Patients With Stage IIIB (With Pleural Effusion) or Stage IV Non-Small Cell Lung Cancer

    Not yet reported National Cancer Institute (NCI) 50 participants 1 site
    Other conditions: Recurrent Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT00079456

    Temsirolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma

    Not yet reported National Cancer Institute (NCI) 25 participants 2 sites
    Other conditions: Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00081874

    RAD001 in Relapsed or Refractory AML, ALL, CML in Blastic-Phase, Agnogenic Myeloid Metaplasia, CLL, T-Cell Leukemia, or Mantle Cell Lymphoma

    Not yet reported, Not yet reported M.D. Anderson Cancer Center 29 participants Est. completion 2006-09 1 site
    Other conditions: Leukemia, Mantle Cell Lymphoma, Myelofibrosis
    View official trial listing →
  • Terminated NCT NCT00083993

    Study Evaluating CCI-779 and Letrozole in Post-menopausal Women With Breast Cancer

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 1236 participants Est. completion 2006-10 129 sites
    Other conditions: Breast Neoplasms, Neoplasm Metastasis
    View official trial listing →
  • Completed NCT NCT00084916

    CCI-779 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, or Chronic Myelogenous Leukemia in Blastic Phase

    Not yet reported National Cancer Institute (NCI) 74 participants 1 site
    Other conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Blastic Phase Chronic Myelogenous Leukemia, Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Excess Blasts in Transformation, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00085566

    Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate Cancer

    Not yet reported, Not yet reported Memorial Sloan Kettering Cancer Center 61 participants Est. completion 2008-02 2 sites
    Other conditions: Brain and Central Nervous System Tumors, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00086125

    Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 57 participants Est. completion 2006-06 8 sites
    Other conditions: Hematologic Malignancies, Leukemia, Myelodysplastic Syndromes, Myeloid Metaplasia, Lymphoma
    View official trial listing →
  • Terminated NCT NCT00086346

    Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 607 participants Est. completion 2008-07 42 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Terminated NCT NCT00086840

    CCI-779 in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia

    Not yet reported National Cancer Institute (NCI) 60 participants 1 site
    Other conditions: Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia
    View official trial listing →
  • Completed NCT NCT00087074

    CCI-779 in Treating Patients With Soft Tissue Sarcoma or Gastrointestinal Stromal Tumor

    Not yet reported National Cancer Institute (NCI) 55 participants 1 site
    Other conditions: Gastrointestinal Stromal Tumor, Recurrent Adult Soft Tissue Sarcoma, Stage I Adult Soft Tissue Sarcoma, Stage II Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma
    View official trial listing →
  • Completed NCT NCT00087685

    RAD001 in Recurrent Endometrial Cancer Patients

    Not yet reported M.D. Anderson Cancer Center 35 participants Est. completion 2015-01 1 site
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT00089037

    Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation

    Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2005-04 1 site
    Other conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
    View official trial listing →
  • Active, not recruiting NCT NCT00092222

    Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

    Not yet reported National Cancer Institute (NCI) 75 participants Est. completion 2026-10-01 1 site
    Other conditions: Lymphoproliferative Disorder, HHV-8, Malignancy, HIV
    View official trial listing →
  • Completed NCT NCT00093080

    Study of AP23573/MK-8669 (Ridaforolimus), A Mammalian Target of Rapamycin (mTOR) Inhibitor, in Participants With Advanced Sarcoma (MK-8669-018 AM1)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 216 participants Est. completion 2008-11
    Obstructive sleep apnea Other conditions: Sarcoma, Soft Tissue, Metastases
    View official trial listing →
  • Completed NCT NCT00093639

    Everolimus and Imatinib Mesylate in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Who Are Not in Complete Cytogenetic Remission After Previous Imatinib Mesylate

    Not yet reported, Not yet reported Novartis Pharmaceuticals Est. completion 2006-08 1 site
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00093782

    Temsirolimus in Treating Patients With Metastatic Neuroendocrine Carcinoma

    Not yet reported National Cancer Institute (NCI) 36 participants Est. completion 2011-04 1 site
    Other conditions: Metastatic Gastrointestinal Carcinoid Tumor, Pulmonary Carcinoid Tumor, Recurrent Gastrointestinal Carcinoid Tumor, Recurrent Islet Cell Carcinoma
    View official trial listing →
  • Terminated NCT NCT00095329

    Treating Multiple Sclerosis With Sirolimus, an Immune System Suppressor

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 14 participants Est. completion 2005-03 1 site Stand-alone
    Other conditions: Multiple Sclerosis (MS) - Relapsing-remitting
    View official trial listing →
  • Completed NCT NCT00097968

    Safety/Efficacy of Everolimus and Neoral® in Adult Cardiac Transplant Patients With Established Allograft Vasculopathy

    Not yet reported Novartis Pharmaceuticals 6 sites
    Other conditions: Graft Rejection
    View official trial listing →
  • Completed NCT NCT00098007

    A Study of Safety, Tolerability & Efficacy of Certican in de Novo Heart Transplant (Tx) Patients

    Not yet reported Novartis Pharmaceuticals 199 participants Est. completion 2007-01-08 28 sites
    Other conditions: Heart Transplantation
    View official trial listing →
  • Completed NCT NCT00098241

    Safety & Efficacy of Certican in Pediatric de Novo Renal Transplant Patients

    Not yet reported Novartis Pharmaceuticals 45 participants Est. completion 2007-03 2 sites
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Withdrawn NCT NCT00098462

    Gefitinib and Sirolimus in Treating Patients With Recurrent or Refractory Stage IIIB or Stage IV Non-Small Cell Lung Cancer

    Not yet reported, Not yet reported Jonsson Comprehensive Cancer Center
    Other conditions: Lung Cancer
    View official trial listing →
  • Completed NCT NCT00098501

    CCI-779 and EKB-569 in Treating Patients With Advanced Solid Tumors

    Not yet reported National Cancer Institute (NCI) 42 participants 1 site
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00098553

    Everolimus in Treating Patients With Stage IV Melanoma

    Not yet reported Alliance for Clinical Trials in Oncology 53 participants Est. completion 2010-02 94 sites
    Other conditions: Melanoma (Skin)
    View official trial listing →
  • Terminated NCT NCT00101088

    Temsirolimus and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia

    Not yet reported National Cancer Institute (NCI) 21 participants 1 site
    Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Blastic Phase Chronic Myelogenous Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Phase Chronic Myelogenous Leukemia, Relapsing Chronic Myelogenous Leukemia
    View official trial listing →
  • Completed NCT NCT00105001

    Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer

    Not yet reported Fred Hutchinson Cancer Center 210 participants Est. completion 2015-05-08 11 sites Stand-alone
    Other conditions: Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndrome, Refractory Chronic Lymphocytic Leukemia, Refractory Plasma Cell Myeloma, Waldenstrom Macroglobulinemia, Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL, Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11, Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA, Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Lymphoma, Childhood Myelodysplastic Syndrome, Stage II Contiguous Adult Burkitt Lymphoma, Stage II Contiguous Adult Diffuse Large Cell Lymphoma, Stage II Contiguous Adult Diffuse Mixed Cell Lymphoma, Stage II Contiguous Adult Diffuse Small Cleaved Cell Lymphoma, Stage II Adult Contiguous Immunoblastic Lymphoma, Stage II Contiguous Adult Lymphoblastic Lymphoma, Stage II Grade 1 Contiguous Follicular Lymphoma, Stage II Grade 2 Contiguous Follicular Lymphoma, Stage II Grade 3 Contiguous Follicular Lymphoma, Stage II Contiguous Mantle Cell Lymphoma, Stage II Non-Contiguous Adult Burkitt Lymphoma, Stage II Non-Contiguous Adult Diffuse Large Cell Lymphoma, Stage II Non-Contiguous Adult Diffuse Mixed Cell Lymphoma, Stage II Non-Contiguous Adult Diffuse Small Cleaved Cell Lymphoma, Stage II Adult Non-Contiguous Immunoblastic Lymphoma, Stage II Non-Contiguous Adult Lymphoblastic Lymphoma, Stage II Grade 1 Non-Contiguous Follicular Lymphoma, Stage II Grade 2 Non-Contiguous Follicular Lymphoma, Stage II Grade 3 Non-Contiguous Follicular Lymphoma, Stage II Non-Contiguous Mantle Cell Lymphoma, Stage II Small Lymphocytic Lymphoma, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Burkitt Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Recurrent Childhood Hodgkin Lymphoma, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Secondary Myelodysplastic Syndrome, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Immunoblastic Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Childhood Anaplastic Large Cell Lymphoma, Stage I Childhood Large Cell Lymphoma, Stage I Childhood Lymphoblastic Lymphoma, Stage I Childhood Burkitt Lymphoma, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Small Lymphocytic Lymphoma, Stage II Childhood Anaplastic Large Cell Lymphoma, Stage II Childhood Lymphoblastic Lymphoma, Stage II Childhood Burkitt Lymphoma, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Immunoblastic Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Childhood Anaplastic Large Cell Lymphoma, Stage III Childhood Large Cell Lymphoma, Stage III Childhood Lymphoblastic Lymphoma, Stage III Childhood Burkitt Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Small Lymphocytic Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Immunoblastic Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Childhood Anaplastic Large Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma, Stage IV Childhood Lymphoblastic Lymphoma, Stage IV Childhood Burkitt Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Small Lymphocytic Lymphoma
    View official trial listing →
  • Completed NCT NCT00106353

    Study Evaluating Biomarkers In Relapsed/Refractory Pediatric Solid Tumors

    Not yet reported, Not yet reported Pfizer 71 participants Est. completion 2012-01 30 sites
    Other conditions: Adenocarcinoma, Neoplasms
    View official trial listing →
  • Completed NCT NCT00107016

    Everolimus and Letrozole as Preoperative Therapy of Primary Breast Cancer in Post-menopausal Women

    Not yet reported Novartis Pharmaceuticals 267 participants Est. completion 2007-04 46 sites
    Other conditions: Breast Neoplasm
    View official trial listing →
  • Completed NCT NCT00107237

    AEE788 and Everolimus in Treating Patients With Recurrent or Relapsed Glioblastoma Multiforme

    Not yet reported, Not yet reported Novartis Pharmaceuticals 16 participants Est. completion 2006-06 3 sites
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Completed NCT NCT00109967

    CCI-779 and Rituximab in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

    Not yet reported National Cancer Institute (NCI) 71 participants Est. completion 2012-03 195 sites
    Other conditions: Recurrent Mantle Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT00112476

    Temsirolimus and Bryostatin 1 in Treating Patients With Unresectable or Metastatic Solid Tumors

    Not yet reported National Cancer Institute (NCI) 24 participants 1 site
    Other conditions: Recurrent Melanoma, Recurrent Renal Cell Cancer, Stage IV Melanoma, Stage IV Renal Cell Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00112736

    Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 69 participants Est. completion 2014-04 8 sites
    Obstructive sleep apnea Other conditions: Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Adult Diffuse Astrocytoma, Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Mixed Glioma, Adult Pilocytic Astrocytoma, Adult Pineal Gland Astrocytoma, Adult Subependymal Giant Cell Astrocytoma, Recurrent Adult Brain Tumor
    View official trial listing →
  • Completed NCT NCT00112840

    CCI-779 and Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney Cancer

    Not yet reported, Not yet reported National Cancer Institute (NCI) 60 participants Est. completion 2015-09-10 2 sites
    Other conditions: Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Cancer, Stage IV Renal Cell Cancer
    View official trial listing →
  • Completed NCT NCT00113360

    RAD001 Plus Octreotide Depot in Metastatic or Unresectable Low Grade Neuroendocrine Carcinoma

    Not yet reported M.D. Anderson Cancer Center 67 participants Est. completion 2009-07 1 site
    Other conditions: Neuroendocrine Carcinoma, Islet Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00117598

    Study Evaluating Temsirolimus (CCI-779) In Mantle Cell Lymphoma (MCL)

    Not yet reported Pfizer 169 participants Est. completion 2011-01 73 sites
    Other conditions: Lymphoma
    View official trial listing →
  • Terminated NCT NCT00117702

    Prevention of the Graft-Versus-Host-Disease in Patients After Stem Cell Transplantation With Tacrolimus and Everolimus

    Not yet reported, Not yet reported Technische Universität Dresden 24 participants Est. completion 2008-05 1 site
    Other conditions: Graft vs Host Disease
    View official trial listing →
  • Completed NCT NCT00118742

    Liver Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Sirolimus in Recipients of a Liver Transplant

    Not yet reported Hoffmann-La Roche 293 participants Est. completion 2008-12 46 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Terminated NCT NCT00121784

    Heart Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Heart Transplant Recipients

    Not yet reported Hoffmann-La Roche 12 participants Est. completion 2006-08 29 sites
    Other conditions: Heart Transplantation
    View official trial listing →
  • Completed NCT NCT00121810

    Kidney Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Kidney Transplant Recipients

    Not yet reported Hoffmann-La Roche 305 participants Est. completion 2009-11 36 sites Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00122343

    AP23573 in Female Adult Patients With Recurrent or Persistent Endometrial Cancer (8669-019)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 45 participants Est. completion 2008-01
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT00123331

    Rapamycin Use in Calcineurin Inhibitor (CNI)-Free Immunosuppression for Stabilization/Improvement of Renal Function After Heart Transplantation

    Not yet reported Heidelberg University 40 participants Est. completion 2005-04 1 site
    Other conditions: Heart Transplantation, Renal Failure
    View official trial listing →
  • Completed NCT NCT00124280

    Study Investigating the Effect of Everolimus Monotherapy in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)

    Not yet reported Novartis Pharmaceuticals 85 participants 2 sites
    Other conditions: Non-small-cell Lung Carcinoma
    View official trial listing →
  • Completed NCT NCT00126672

    RAPAMYCIN FOR KIDNEY ANGIOMYOLIPOMAS

    Not yet reported Dana-Farber Cancer Institute 36 participants Est. completion 2010-04 7 sites
    Other conditions: Nonmalignant Neoplasm, Tuberous Sclerosis, Lymphangioleimyomatosis, Kidney Angiomyolipoma
    View official trial listing →
  • Completed NCT NCT00129961

    Study Evaluating the Effect of Sirolimus on Non-Melanoma Skin Cancer in Kidney Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 86 participants Est. completion 2009-01 23 sites Stand-alone
    Other conditions: Skin Neoplasms, Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00130546

    Intra-Individual Comparison of Sirolimus and Paclitaxel Coated Stent (FRE-RACE Study)

    Not yet reported University Hospital Freiburg 112 participants Est. completion 2008-07 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00133237

    Drug-eluting-stents for Unprotected Left Main Stem Disease (ISAR-LEFT-MAIN)

    Not yet reported Deutsches Herzzentrum Muenchen 607 participants Est. completion 2008-06 2 sites
    Other conditions: Coronary Disease
    View official trial listing →
  • Completed NCT NCT00133367

    Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus

    Not yet reported Massachusetts General Hospital 32 participants Est. completion 2011-11 2 sites
    Other conditions: Multiple Myeloma, Non-Hodgkin's Lymphoma, Hodgkin's Disease, Myelogenous Leukemia, Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00133887

    TUMORAPA 1: Efficacy of Rapamycin in Secondary Prevention of Skin Cancers in Kidney Transplant Recipients

    Not yet reported Hospices Civils de Lyon 77 participants Est. completion 2014-05 1 site
    Other conditions: Skin Cancer, Kidney Transplantation
    View official trial listing →
  • Terminated NCT NCT00137345

    Study Comparing Sirolimus With Cyclosporine in a Calcineurin Inhibitor (CNI)-Free Regimen in Kidney Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 500 participants Est. completion 2006-08 82 sites
    Other conditions: Kidney Transplant
    View official trial listing →
  • Completed NCT NCT00139386

    Candesartan for Prevention of Cardiovascular Events After Cypher or Taxus Coronary Stenting (4C) Trial

    Not yet reported Kumamoto University 1119 participants Est. completion 2012-04 1 site
    Cardiovascular disease Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT00140530

    Nonpolymer- and Polymer-Based Drug-Eluting Stents for Restenosis (ISAR-TEST-1)

    Not yet reported Deutsches Herzzentrum Muenchen 450 participants Est. completion 2005-06 2 sites
    Other conditions: Coronary Disease
    View official trial listing →
  • Completed NCT NCT00140543

    European Trial of Immunosuppression in SPK Tx

    Not yet reported EUROSPK Study Group 228 participants Est. completion 2005-09-30 14 sites
    Chronic kidney disease Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Status unknown NCT NCT00141804

    Efficacy and Safety of Sirolimus in Combination With Tacrolimus

    Not yet reported University Hospital Muenster 190 participants Est. completion 2005-06 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00144677

    Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation

    Not yet reported Dana-Farber Cancer Institute 30 participants Est. completion 2006-06 1 site
    Other conditions: Acute Myelogenous Leukemia, Graft Versus Host Disease, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndromes, Non-Hodgkin's Lymphoma, Hodgkin's Disease
    View official trial listing →
  • Completed NCT NCT00144703

    Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Related Stem Cell Transplantation

    Not yet reported Dana-Farber Cancer Institute 55 participants Est. completion 2006-11 1 site
    Other conditions: Hematologic Malignancies, Myelogenous Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, Non-Hodgkin's Lymphoma, Hodgkin's Disease
    View official trial listing →
  • Completed NCT NCT00146575

    Sirolimus- and Paclitaxel-Eluting Stents for Small Vessels (ISAR-SMART-3)

    Not yet reported Deutsches Herzzentrum Muenchen 360 participants Est. completion 2005-02 2 sites Stand-alone
    Other conditions: Coronary Disease
    View official trial listing →
  • Completed NCT NCT00146614

    Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation

    Not yet reported Dana-Farber Cancer Institute 105 participants Est. completion 2003-04 3 sites
    Other conditions: Graft Versus Host Disease, Hematologic Malignancies
    View official trial listing →
  • No Longer Available NCT NCT00149981

    A Facilitated Access Program to Provide Everolimus (RAD) Maintenance for Patients Completing Therapy in RAD Trials in Solid Organ Transplantation

    Novartis Pharmaceuticals 153 sites
    Other conditions: Organ Transplantation
    View official trial listing →
  • Completed NCT NCT00150046

    Efficacy and Safety of Everolimus in de Novo Heart Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 176 participants 2 sites
    Other conditions: Heart Transplantation
    View official trial listing →
  • Completed NCT NCT00151658

    Sirolimus Eluting Stents in Complex Coronary Lesions (SCANDSTENT)

    Not yet reported Copenhagen University Hospital, Rigshospitalet 322 participants Est. completion 2006-06 1 site
    Other conditions: Ischaemic Heart Disease
    View official trial listing →
  • Completed NCT NCT00154284

    Everolimus in a Cyclosporine Microemulsion-free Regimen Compared to a Low-dose Cyclosporine Microemulsion Regimen, in de Novo Kidney Transplant Patients

    Not yet reported Novartis 114 participants Est. completion 2008-07
    Other conditions: Organ Transplantation, Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00154297

    Efficacy and Safety of Early Versus Delayed Administration of Everolimus in de Novo Renal Transplant Patients

    Not yet reported Novartis Pharmaceuticals 139 participants 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00154310

    Efficacy and Safety of Everolimus With Enteric-Coated Mycophenolate Sodium (EC-MPS) in a Cyclosporine Microemulsion-free Regimen Compared to Standard Therapy in de Novo Renal Transplant Patients

    Not yet reported Novartis 300 participants Est. completion 2008-09 3 sites
    Other conditions: Renal Transplantation
    View official trial listing →
  • Active, not recruiting NCT NCT00160732

    Allogenic Islet Cell Transplantation

    Not yet reported, Not yet reported University of Chicago 50 participants Est. completion 2030-10 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Terminated NCT NCT00166712

    A Trial of Two Steroid-Free Approaches Toward Mycophenolate Mofetil-Based Monotherapy Immunosuppression

    Not yet reported Northwestern University 40 participants Est. completion 2010-04 1 site
    Other conditions: Kidney Transplant Failure and Rejection
    View official trial listing →
  • Status unknown NCT NCT00166816

    The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients

    Not yet reported National Taiwan University Hospital 40 participants Est. completion 2003-06 1 site
    Other conditions: Transplantation, Kidney Transplantation, Immunosuppression
    View official trial listing →
  • Status unknown NCT NCT00166829

    The Effect of Sirolimus on the Pharmacokinetics of Tacrolimus

    Not yet reported National Taiwan University Hospital 40 participants 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Status unknown NCT NCT00166842

    Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets

    Not yet reported National Taiwan University Hospital 40 participants 1 site
    Other conditions: Transplantation, Kidney Transplantation, Immunosuppression
    View official trial listing →
  • Completed NCT NCT00167947

    Study Evaluating Sirolimus in Kidney Transplant Recipients.

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 150 participants Est. completion 2007-07 14 sites Stand-alone
    Other conditions: Kidney Failure, Graft vs Host Disease
    View official trial listing →
  • Completed NCT NCT00170053

    Comparison of Sirolimus to Tacrolimus for Long Term Therapy in Kidney Transplant With no Steroids

    Not yet reported Mayo Clinic 177 participants Est. completion 2008-09 1 site
    Other conditions: Kidney Diseases
    View official trial listing →
  • Completed NCT NCT00170794

    Renal Safety of Everolimus in Addition to Cyclosporine Microemulsion in Cardiac Transplant Recipients.

    Not yet reported Novartis Pharmaceuticals
    Other conditions: Cardiac Transplantation
    View official trial listing →
  • Completed NCT NCT00170820

    Efficacy and Safety of the Switch From Sirolimus to Everolimus in Stable Maintenance Renal Transplant Patients Receiving a Calcineurin Inhibitor Free Regimen

    Not yet reported Novartis Pharmaceuticals 20 participants 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00170833

    Safety, Tolerability and Efficacy of Everolimus With Lower Versus Higher Levels of Tacrolimus in de Novo Renal Transplant Patients

    Not yet reported Novartis Pharmaceuticals 80 participants
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00170846

    ASCERTAIN: Assessment of Everolimus in Addition to Calcineurin Inhibitor Reduction in the Maintenance of Renal Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 394 participants Est. completion 2009-10 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00170859

    Everolimus Versus Mycophenolate Mofetil in Combination With Reduced Dose Cyclosporine Microemulsion in Maintenance Heart Transplant Recipients

    Not yet reported Novartis Pharmaceuticals Est. completion 2006-12 1 site
    Other conditions: Heart Transplantation
    View official trial listing →
  • Completed NCT NCT00170885

    Everolimus in Combination With Cyclosporine Microemulsion in de Novo Renal Transplant Recipients

    Not yet reported Novartis Est. completion 2007-07 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00183248

    Using Donor Stem Cells and Alemtuzumab to Prevent Organ Rejection in Kidney Transplant Patients

    Not yet reported, Not yet reported University of Miami 9 participants Est. completion 2009-11 1 site Stand-alone
    Other conditions: Kidney Transplantation, Kidney Disease, Kidney Failure
    View official trial listing →
  • Completed NCT NCT00186667

    Sirolimus as Primary Therapy for the Treatment of Chronic Graft Versus Host Disease

    Not yet reported Stanford University 30 participants Est. completion 2005-09 1 site
    Other conditions: Graft vs Host Disease, Blood and Marrow Transplant (BMT)
    View official trial listing →
  • Completed NCT NCT00187174

    Everolimus for Treating Pediatric Patients With Recurrent or Refractory Tumors

    Not yet reported St. Jude Children's Research Hospital 41 participants Est. completion 2008-10 1 site
    Obstructive sleep apnea Other conditions: Tumors, Brain Tumors, Sarcoma, Soft Tissue
    View official trial listing →
  • Completed NCT NCT00188955

    Pilot Study on the Use of Sirolimus to Treat Chronic Allograft Nephropathy in Children After Kidney Transplant

    Not yet reported University of Manitoba 40 participants Est. completion 2008-10 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00189202

    Efficacy of Sirolimus-Based, Steroid Avoidance Immunosuppression African Americans

    Not yet reported, Not yet reported University of Michigan 49 participants Est. completion 2008-07-01 1 site Stand-alone
    Other conditions: End Stage Renal Disease, Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00195195

    Study Evaluating Rapamune in Transplant Recipients in the Nordic Countries

    Wyeth is now a wholly owned subsidiary of Pfizer 66 participants Est. completion 2008-06 3 sites
    Other conditions: Transplantation
    View official trial listing →
  • Completed NCT NCT00195273

    Study Evaluating Sirolimus in Kidney Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 61 participants Est. completion 2008-07 3 sites Stand-alone
    Other conditions: Graft vs Host Disease, Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00195299

    Study Evaluating Temsirolimus in Advanced Stage Squamous Cell Carcinoma of the Head & Neck

    Wyeth is now a wholly owned subsidiary of Pfizer 20 participants Est. completion 2007-02 1 site
    Other conditions: Squamous Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00195429

    A Study Comparing the Withdrawal of Steroids or Tacrolimus in Kidney Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 47 participants Est. completion 2007-10 1 site Stand-alone
    Other conditions: Kidney Failure, Graft vs Host Disease
    View official trial listing →
  • Completed NCT NCT00195468

    Study Comparing Cyclosporine Dose Reduction vs. Cyclosporine Elimination in Kidney Transplant Recipients Taking Sirolimus

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 280 participants Est. completion 2006-11 13 sites
    Other conditions: Kidney Failure, Graft vs Host Disease
    View official trial listing →
  • Completed NCT NCT00195481

    Study Evaluating Sirolimus in Kidney Transplant Recipients in India

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 100 participants Est. completion 2005-12 5 sites
    Other conditions: Kidney Failure, Graft vs Host Disease
    View official trial listing →
  • Completed NCT NCT00204321

    Influence of Sirolimus and MMF on Vascular Function and Markers of Cellular Function in Renal Transplant Recipients

    Not yet reported University Hospital Muenster 80 participants Est. completion 2010-01 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00217256

    The Medtronic Endeavor III Drug Eluting Coronary Stent System Clinical Trial

    Not yet reported Medtronic Vascular 436 participants Est. completion 2010-12
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT00220558

    GISSOC II: Sirolimus Eluting Stent Versus Bare Metal Stent in Chronic Total Coronary Occlusions

    Not yet reported Società Italiana di Cardiologia Invasiva 150 participants Est. completion 2010-02 14 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00223028

    Investigation of the Steady State Pharmacokinetics of Sirolimus, Mycophenolat Mofetil and Fluvastatin After Renal Transplantation

    Not yet reported University Hospital Schleswig-Holstein 15 participants Est. completion 2005-07
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00223054

    Polymorphism of the Cytochrome P450-system in Renal Transplants

    University Hospital Schleswig-Holstein 200 participants Est. completion 2006-10 1 site
    Other conditions: Function of Renal Transplant
    View official trial listing →
  • Completed NCT NCT00223678

    Mycophenolate Mofetil and Rapamycin as Secondary Intervention vs. Continuation of Calcineurin Inhibitors in Patients at Risk for Chronic Renal Allograft Failure

    Not yet reported Vanderbilt University Medical Center 20 participants Est. completion 2009-10 1 site
    Other conditions: Kidney Transplant
    View official trial listing →
  • Completed NCT NCT00228397

    Study Evaluating CCI-779 in Relapsing Multiple Sclerosis

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 221 participants Est. completion 2005-11
    Other conditions: Multiple Sclerosis, Relapsing-Remitting
    View official trial listing →
  • Status unknown NCT NCT00229515

    Multicentre 2x2 Factorial Randomised Study Comparing Tirofiban Versus Abciximab and SES Versus BMS in AMI

    Not yet reported Marco Valgimigli 744 participants Est. completion 2012-03 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00231244

    Sirolimus-Eluting BX VELOCITYTM Balloon-Expandable Stent in a Compassionate Use Registry (SECURE)

    Not yet reported Cordis US Corp. 252 participants Est. completion 2008-11 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00231257

    Sirolimus-Eluting Stent vs. Intravascular Brachytherapy in In-Stent Restenotic Coronary Artery Lesions(SISR)

    Not yet reported Cordis US Corp. 384 participants Est. completion 2009-09 1 site Stand-alone
    Other conditions: In-Stent Restenosis
    View official trial listing →
  • Completed NCT NCT00231283

    NEXUS Study for the Treatment of de Novo Native Coronary Artery Lesions

    Not yet reported Cordis US Corp. 100 participants Est. completion 2005-07 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00232739

    Study of the 2.25mm Sirolimus-Eluting Stent in the Treatment of Patients With Coronary Artery Lesions

    Not yet reported Cordis US Corp. 100 participants Est. completion 2009-08 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00232752

    Study of the 4.0mm Sirolimus-Eluting Stent in the Treatment of Patients With Coronary Artery Lesions

    Not yet reported Cordis US Corp. 100 participants Est. completion 2009-11 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00232765

    Study of Sirolimus-Coated BX VELOCITY Balloon-Expandable Stent in Treatment of de Novo Native Coronary Artery Lesions (SIRIUS)

    Not yet reported Cordis US Corp. 1058 participants Est. completion 2008-11 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00232791

    The Study to Compare Cypher Versus Cypher Select in Treating Cornary Artery Lesions.

    Not yet reported, Not yet reported Cordis US Corp. 102 participants Est. completion 2005-03 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00232830

    The Study to Assess AMI Treated With Balloon Angioplasty.

    Not yet reported Cordis US Corp. 715 participants Est. completion 2009-04 2 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00232856

    A Study of the Cypher SES to Treat Restenotic Native Coronary Artery Lesions.

    Not yet reported Cordis US Corp. 162 participants Est. completion 2006-08 2 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00232869

    A Study of the SMART Stent in the Treatment SFA Disease.

    Not yet reported Cordis US Corp. 93 participants Est. completion 2009-05 1 site Stand-alone
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Completed NCT NCT00233714

    Double or Single Dose Sirolimus-Eluting Stents in Diabetic Patients With de Novo Coronary Artery Lesions

    Not yet reported, Not yet reported Cordis US Corp. 56 participants Est. completion 2009-11 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00233766

    Evaluation of Two Reduced Sirolimus Doses in Treatment of de Novo Coronary Artery Lesions (REDOX)

    Not yet reported, Not yet reported Cordis US Corp. 60 participants Est. completion 2007-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00233779

    Evaluation of Sirolimus-Eluting, Heparin-Coated CoCr Stent in the Treatment of de Novo Coronary Artery Lesions in Small Vessels(EVOLUTION)

    Not yet reported Cordis US Corp. 52 participants Est. completion 2004-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00233792

    FIM-BR - First-in-Man Study (Brazil Part) With Sirolimus-Coated BX VELOCITY Stent

    Not yet reported, Not yet reported Cordis US Corp. 30 participants Est. completion 2005-03 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00233805

    The Initial Double-Blind Drug-Eluting Stent vs Bare-Metal Stent Study.

    Not yet reported Cordis US Corp. 220 participants Est. completion 2007-12 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00233818

    FIM-NL - First-in-Man Study (Netherlands Part) With Sirolimus Coated Modified BX Velocity Stent

    Not yet reported, Not yet reported Cordis US Corp. 15 participants Est. completion 2005-06 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00234455

    A Study of the Cypher Sirolimus-Eluting Stent to Treat Bifurcation Lesions.

    Not yet reported Cordis US Corp. 86 participants Est. completion 2007-04 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00235066

    The CYPHER™ Stent Study in Patients With Small de Novo Coronary Artery Lesions.

    Not yet reported Cordis US Corp. 100 participants Est. completion 2006-04 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00235092

    The REALITY Study - Head-to-Head Comparison Between Cypher and Taxus

    Not yet reported Cordis US Corp. 1335 participants Est. completion 2006-03 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00235144

    The Study of the BX VELOCITY Stent In Patients With De Novo Coronary Artery Lesions.

    Not yet reported Cordis US Corp. 353 participants Est. completion 2008-09 2 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00235157

    A Comparison of Coated and Uncoated Stents in Renal Artery Treatment.

    Not yet reported Cordis US Corp. 105 participants Est. completion 2005-07 3 sites Stand-alone
    Other conditions: Renal Artery Stenosis
    View official trial listing →
  • Completed NCT NCT00235170

    The Arterial Revascularization Therapies Study Part II.

    Not yet reported Cordis US Corp. 607 participants Est. completion 2009-04 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00235560

    Rapamycin in Combination With Low-dose Aracytin in Elderly Acute Myeloid Leukemia Patients

    Not yet reported University Hospital, Toulouse 50 participants Est. completion 2008-06 3 sites Stand-alone
    Other conditions: Acute Myeloid Leukemia
    View official trial listing →
  • Completed NCT NCT00235794

    An Open Label Exploratory Study in Newly Diagnosed Prostate Cancer Patients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 50 participants Est. completion 2007-09 1 site
    Other conditions: Prostatic Neoplasms
    View official trial listing →
  • Terminated NCT NCT00240214

    Study Evaluating Rapamune in Patients After Kidney Transplantation

    Wyeth is now a wholly owned subsidiary of Pfizer 500 participants Est. completion 2008-02 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00240994

    Safety in Immunomodulatory Functions of Alemtuzumab (Campath) in Pediatric Kidney Transplantation Recipients

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 35 participants Est. completion 2009-11 4 sites Stand-alone
    Other conditions: Kidney Failure, Chronic, Kidney Transplantation, Immunosuppression
    View official trial listing →
  • Completed NCT NCT00241189

    Rapamycin vs Methotrexate in Diffuse SSc

    Not yet reported, Not yet reported University of California, Los Angeles 17 participants Est. completion 2006-06 1 site
    Other conditions: Systemic Sclerosis
    View official trial listing →
  • Completed NCT NCT00245401

    CYPHERTM Stent Post-Marketing Surveillance Registry (US-PMS)

    Not yet reported Cordis US Corp. 2070 participants Est. completion 2004-12
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00248313

    Study Comparing Cyclosporin Dose Reduction With Cyclosporin Elimination in Kidney Transplant Recipients Taking Sirolimus

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 470 participants Est. completion 2007-10
    Other conditions: Kidney Disease
    View official trial listing →
  • Status unknown NCT NCT00252655

    Use of Sirolimus vs. Tacrolimus For African-American Renal Transplant Recipients

    Not yet reported Wayne State University 40 participants Est. completion 2009-06 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Terminated NCT NCT00253318

    RAD001 Plus Docetaxel in Patients With Metastatic Breast Cancer

    Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2012-04 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00254709

    Study Evaluating Two Different Sirolimus-based Immunosuppressive Regimens in Elderly Kidney Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 66 participants Est. completion 2005-09
    Other conditions: Kidney Failure, Graft Rejection, Aged
    View official trial listing →
  • Completed NCT NCT00255658

    Sorafenib and Temsirolimus in Treating Patients With Unresectable or Metastatic Solid Tumors

    Not yet reported National Cancer Institute (NCI) 40 participants Est. completion 2007-04 1 site
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00255788

    Everolimus in Treating Patients WIth Recurrent or Metastatic Breast Cancer

    Not yet reported NCIC Clinical Trials Group 49 participants Est. completion 2011-01-18 5 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00257387

    Study Evaluating Cyclosporine Dose Reduction and Cyclosporine Elimination in Chinese Kidney Transplants

    Not yet reported, Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 120 participants Est. completion 2006-08
    Other conditions: Kidney Transplant
    View official trial listing →
  • Completed NCT NCT00258596

    Sirolimus-Eluting Stents for Chronic Total Coronary Occlusions

    Not yet reported R&D Cardiologie 200 participants Est. completion 2006-09 2 sites
    Cardiovascular disease Other conditions: Coronary Disease, Coronary Stenosis
    View official trial listing →
  • Completed NCT NCT00261820

    Study Comparing Two Immunosuppressive Regimens in De Novo Renal Allograft Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 160 participants Est. completion 2005-01
    Other conditions: Graft Rejection, Kidney Failure, Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00263263

    RRISC Study: Reduction of Restenosis In Saphenous Vein Grafts With Cypher Sirolimus-Eluting Stent.

    Not yet reported Antwerp Cardiovascular Institute Middelheim 75 participants Est. completion 2005-12 1 site
    Cardiovascular disease Other conditions: Stable Angina, Unstable Angina, Saphenous Vein Graft Disease
    View official trial listing →
  • Completed NCT NCT00265473

    MGA031, Sirolimus and Tacrolimus in Islet Transplantation

    Not yet reported, Not yet reported University of Minnesota 5 participants Est. completion 2010-06 1 site
    Other conditions: Type 1 Diabetes Mellitus, Hypoglycemia
    View official trial listing →
  • Completed NCT NCT00267189

    RESCUE Study - Everolimus in Liver Transplantation Recipients With Renal Insufficiency

    Not yet reported Novartis Pharmaceuticals 145 participants Est. completion 2007-11 2 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Completed NCT NCT00273871

    Study Comparing Conversion From Calcineurin Inhibitors to Rapamune Versus Standard Therapy in Established Renal Allograft Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 190 participants Est. completion 2006-09
    Other conditions: Graft Rejection, Kidney Failure, Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00275093

    Temsirolimus in Treating Patients With Metastatic Solid Tumor or Lymphoma That Cannot Be Removed By Surgery Who Have Different Levels of Liver Function

    Not yet reported National Cancer Institute (NCI) 130 participants 1 site
    Other conditions: Hepatic Complications, Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00275522

    The Comparison of Three Different Immunosuppressant Regimens in Kidney Transplant Recipients.

    Not yet reported Mayo Clinic 16 participants Est. completion 2007-12 1 site
    Other conditions: Kidney Transplant
    View official trial listing →
  • Completed NCT NCT00275535

    The Comparison of Tacrolimus and Sirolimus Immunosuppression Based Drug Regimens in Kidney Transplant Recipients

    Not yet reported Mayo Clinic 165 participants Est. completion 2008-12 1 site
    Other conditions: Kidney Diseases
    View official trial listing →
  • Completed NCT NCT00276575

    Bevacizumab, Everolimus, and Erlotinib in Treating Patients With Advanced Solid Tumors

    Not yet reported Herbert Hurwitz, MD 65 participants Est. completion 2014-09 1 site
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Terminated NCT NCT00276744

    Individualized Drug Treatment for Treating Patients With Pancreatic Cancer

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 249 participants Est. completion 2010-04 1 site
    Other conditions: Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT00281957

    Sorafenib With Either Temsirolimus or Tipifarnib in Treating Patients With Stage IV Malignant Melanoma That Cannot Be Removed By Surgery

    Not yet reported National Cancer Institute (NCI) 109 participants Est. completion 2011-01 173 sites
    Other conditions: Recurrent Melanoma, Stage IV Melanoma
    View official trial listing →
  • Completed NCT NCT00282217

    Study Evaluating Sirolimus in the Treatment of Kidney Transplant

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 100 participants 13 sites
    Other conditions: Kidney Failure, Kidney Diseases
    View official trial listing →
  • Completed NCT NCT00282282

    Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-myeloablative Peripheral Blood Stem Cell Transplantation

    Not yet reported Dana-Farber Cancer Institute 31 participants Est. completion 2009-07 1 site
    Other conditions: Graft Versus Host Disease, GVHD
    View official trial listing →
  • Completed NCT NCT00285194

    hOKT3γ1 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients

    Not yet reported, Not yet reported University of Minnesota 6 participants Est. completion 2004-01 1 site
    Other conditions: Type 1 Diabetes, Hypoglycemia
    View official trial listing →
  • Completed NCT NCT00285233

    Delayed Mycophenolate Mofetil in Single-Donor Islet Allotransplantation in Type 1 Diabetes

    Not yet reported, Not yet reported University of Minnesota 8 participants Est. completion 2005-03 1 site
    Other conditions: Type 1 Diabetes, Hypoglycemia
    View official trial listing →
  • Completed NCT NCT00286156

    Pilot Study of Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD)

    Not yet reported, Not yet reported The Cleveland Clinic 30 participants Est. completion 2014-12 1 site
    Other conditions: Polycystic Kidney Diseases
    View official trial listing →
  • Completed NCT NCT00286624

    Anti-Thymocyte Globulin, Cyclosporine, and RAD in Islet Transplantation

    Not yet reported, Not yet reported University of Minnesota 6 participants Est. completion 2006-08 1 site
    Other conditions: Type 1 Diabetes Mellitus, Hypoglycemia
    View official trial listing →
  • Status unknown NCT NCT00288210

    Sirolimus Eluting Stenting in Acute Myocardial Infarction

    Not yet reported San Camillo Hospital, Rome Est. completion 2006-03 1 site
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT00288535

    Treatment of Bifurcated Coronary Lesions With Cypher™-Stent

    Not yet reported University Heart Center Freiburg - Bad Krozingen 200 participants Est. completion 2007-02 1 site
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT00290069

    Renal Function Optimization With Mycophenolate Mofetil (MMF) Immunosuppressor Regimes (ALHAMBRA)

    Not yet reported Sociedad Andaluza de Trasplantes de Organos y Tejidos 94 participants 7 sites
    Other conditions: Kidney Diseases, Graft Rejection
    View official trial listing →
  • Completed NCT NCT00290472

    CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia

    Not yet reported National Cancer Institute (NCI) 89 participants Est. completion 2010-04 13 sites
    Obstructive sleep apnea Other conditions: B-cell Chronic Lymphocytic Leukemia, Malignant Neoplasm, Nodal Marginal Zone B-cell Lymphoma, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Splenic Marginal Zone Lymphoma, Waldenström Macroglobulinemia
    View official trial listing →
  • Completed NCT NCT00296361

    To Compare the Efficacy and Safety of a Therapy of Tacrolimus With Sirolimus or MMF in Kidney Transplantation.

    Not yet reported Astellas Pharma Inc 634 participants Est. completion 2006-07 59 sites
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00297661

    Sirolimus-Eluting Versus Paclitaxel-Eluting Stents for Coronary Revascularization

    Not yet reported University of Bern 1012 participants 1 site
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT00300274

    Efficacy and Safety of Everolimus in Recipients of Heart Transplants to Prevent Acute and Chronic Rejection

    Not yet reported Novartis Pharmaceuticals 721 participants Est. completion 2011-07 64 sites
    Other conditions: Graft Rejection
    View official trial listing →
  • Completed NCT NCT00303732

    Vatalanib and Everolimus in Treating Patients With Advanced Solid Tumors

    Not yet reported Daniel George, MD 37 participants Est. completion 2012-08 1 site
    Other conditions: Kidney Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00304954

    Infliximab, Sirolimus and Daclizumab to Treat Age-Related Macular Degeneration

    Not yet reported National Eye Institute (NEI) 13 participants Est. completion 2010-01 1 site
    Other conditions: Age-Related Macular Degeneration, Choroidal Neovascularization
    View official trial listing →
  • Completed NCT NCT00305396

    Calcineurin Inhibitor Avoidance With Thymoglobulin and Sirolimus in Kidney Transplantation

    Not yet reported Vanderbilt University 80 participants Est. completion 2005-03 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00305682

    Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant

    Not yet reported Masonic Cancer Center, University of Minnesota 295 participants Est. completion 2019-12-12 1 site
    Other conditions: Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00306397

    Pilot Study to Investigate a Steroid Free Immunosuppressive Regimen for Renal Transplant Recipients

    Not yet reported University Hospital, Basel, Switzerland 100 participants Est. completion 2008-12 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Withdrawn NCT NCT00309231

    Clinical Islet Transplantation Using the Edmonton Protocol

    London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Est. completion 2008-01 1 site
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT00309270

    Low Dose Sirolimus or CsA-Based Maintenance Immunosuppression After Induction With Campath-1 in Kidney Transplantation

    Not yet reported Mario Negri Institute for Pharmacological Research 21 participants Est. completion 2010-04 1 site
    Other conditions: Kidney Transplant
    View official trial listing →
  • Terminated NCT NCT00311311

    Study Comparing Effect On Carotid Atherosclerosis Following Conversion From Tacrolimus To Sirolimus Post-Transplant In Kidney Transplant Patients

    Not yet reported Pfizer 72 participants Est. completion 2012-01 8 sites Stand-alone
    Other conditions: Atherosclerosis, Kidney Failure
    View official trial listing →
  • Completed NCT NCT00311623

    Sirolimus Before Surgery in Treating Patients With Advanced Localized Prostate Cancer

    Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 32 participants Est. completion 2010-06 3 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00316849

    Temsirolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

    Not yet reported National Cancer Institute (NCI) 56 participants 11 sites
    Obstructive sleep apnea Other conditions: Adult Giant Cell Glioblastoma, Adult Glioblastoma
    View official trial listing →
  • Completed NCT NCT00317785

    Total-Body Irradiation and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer and Other Diseases

    Not yet reported Fred Hutchinson Cancer Center 50 participants 2 sites
    Other conditions: Leukemia, Lymphoma, Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00317798

    Antithymocyte Globulin and Sirolimus in Treating Patients With Relapsed Multiple Myeloma

    Not yet reported University of Rochester 18 participants Est. completion 2011-04 1 site
    Other conditions: Drug/Agent Toxicity by Tissue/Organ, Multiple Myeloma and Plasma Cell Neoplasm
    View official trial listing →
  • Status unknown NCT NCT00319878

    Sirolimus and Cyclosporine for Treatment-Resistant Aplastic Anemia

    Not yet reported, Not yet reported Office of Rare Diseases (ORD) 52 participants Est. completion 2009-12 4 sites Stand-alone
    Other conditions: Anemia, Aplastic
    View official trial listing →
  • Completed NCT NCT00321906

    Comparison of Sirolimus and Azathioprine in Lung Transplantation

    Not yet reported University of Chicago 181 participants Est. completion 2011-08 1 site
    Other conditions: Delayed Graft Function, Acute Graft Rejection
    View official trial listing →
  • Completed NCT NCT00323739

    Bevacizumab (Avastin) and RAD001(Everolimus)in the Treatment of Advanced Clear Cell Renal Carcinoma

    Not yet reported SCRI Development Innovations, LLC 80 participants Est. completion 2011-03 12 sites
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT00323895

    The Intra-Drug Eluting Stent (DES) Restenosis Study

    Not yet reported Cordis US Corp. 320 participants Est. completion 2010-01 2 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT00325325

    Pharmacokinetic Study on the Combination of Everolimus-Tacrolimus

    Not yet reported Hospital Universitario Ramon y Cajal 40 participants Est. completion 2007-06 1 site
    Other conditions: Kidney Diseases
    View official trial listing →
  • Completed NCT NCT00328770

    De Novo Sirolimus-based Immunosuppression After Liver Transplantation for Hepatocellular Carcinoma

    Not yet reported, Not yet reported University of Alberta 70 participants Est. completion 2006-03 1 site Stand-alone
    Other conditions: Liver Carcinoma
    View official trial listing →
  • Completed NCT NCT00329719

    Sorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent Glioblastoma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 115 participants Est. completion 2013-02-02 190 sites
    Obstructive sleep apnea Other conditions: Adult Glioblastoma, Recurrent Adult Brain Neoplasm
    View official trial listing →
  • Completed NCT NCT00331409

    Everolimus and Imatinib Mesylate in Treating Patients With Metastatic or Unresectable Kidney Cancer

    Not yet reported OHSU Knight Cancer Institute 23 participants Est. completion 2010-01 1 site
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT00332397

    The Efficacy of Three Different Limus Agent-Eluting Stents to Prevent Restenosis

    Not yet reported Deutsches Herzzentrum Muenchen 1007 participants Est. completion 2007-07 2 sites
    Other conditions: Coronary Disease
    View official trial listing →
  • Terminated NCT NCT00332839

    Comparison of CNI-based Regimen Versus CNI-free Regimen in Kidney Transplant Recipients.

    Not yet reported Novartis Pharmaceuticals 93 participants Est. completion 2013-03 11 sites
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00335764

    Sorafenib Combined With Erlotinib, Tipifarnib, or Temsirolimus in Treating Patients With Recurrent Glioblastoma Multiforme or Gliosarcoma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 92 participants Est. completion 2012-09 7 sites
    Obstructive sleep apnea Other conditions: Adult Giant Cell Glioblastoma, Adult Glioblastoma, Recurrent Adult Brain Tumor
    View official trial listing →
  • Terminated NCT NCT00337376

    A Study of the mTOR Inhibitor Rapamycin (Rapamune, Sirolimus) in Combination With Abraxane in Advanced Solid Cancers

    Not yet reported Yale University 23 participants Est. completion 2010-07 1 site
    Other conditions: Advanced Solid Cancers
    View official trial listing →
  • Completed NCT NCT00337545

    Phase II Trial of RAD001 in Refractory Colorectal Cancer

    Not yet reported Swedish Medical Center 22 participants Est. completion 2007-04 1 site
    Other conditions: Colorectal Cancer
    View official trial listing →
  • Terminated NCT NCT00346151

    Belatacept to Prevent Organ Rejection in Kidney Transplant Patients

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 5 participants Est. completion 2010-02 2 sites Stand-alone
    Other conditions: Renal Transplant
    View official trial listing →
  • Completed NCT NCT00346918

    Sirolimus (Rapamune®) for Autosomal Dominant Polycystic Kidney Disease (ADPKD)

    Not yet reported University of Zurich 100 participants Est. completion 2010-06 1 site
    Other conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
    View official trial listing →
  • Completed NCT NCT00349206

    Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma

    Not yet reported National Cancer Institute (NCI) 69 participants Est. completion 2012-02 1 site
    Other conditions: Melanoma, Recurrent Melanoma, Stage III Melanoma, Stage IV Melanoma
    View official trial listing →
  • Completed NCT NCT00350181

    Sirolimus & Mycophenolate Mofetil as GVHD Prophylaxis in Myeloablative, Matched Related Donor HCT

    Not yet reported Stanford University 11 participants Est. completion 2010-04 1 site Stand-alone
    Other conditions: Leukemia, Lymphoma, Non-Hodgkin, Hematologic Diseases, Acute GVHD
    View official trial listing →
  • Completed NCT NCT00350454

    Rapamycin-Eluting Stents With Different Polymer Coating to Reduce Restenosis (ISAR-TEST-3)

    Not yet reported Deutsches Herzzentrum Muenchen 605 participants Est. completion 2007-10 2 sites
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT00352092

    Pilot Study for HLA Identical Living Donor Renal Transplant Recipients

    Not yet reported University of Cincinnati 20 participants Est. completion 2007-12 1 site
    Other conditions: Renal Transplant
    View official trial listing →
  • Completed NCT NCT00352443

    S0528 Lapatinib and Everolimus in Treating Patients With Advanced Solid Tumors or Non-Hodgkin's Lymphoma

    Not yet reported SWOG Cancer Research Network 66 participants Est. completion 2013-09 6 sites
    Other conditions: Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00352547

    Influence of Genes on Sirolimus Metabolism in Patients With Kidney Transplantation

    National Institutes of Health Clinical Center (CC) 93 participants Est. completion 2013-12-02 1 site
    Other conditions: Renal Transplant
    View official trial listing →
  • Withdrawn NCT NCT00352950

    Safety Evaluation of Panitumumab and Sirolimus in Advanced Non-Small Cell Lung Cancer

    Not yet reported Amgen Est. completion 2008-02
    Other conditions: Oncology, Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT00352976

    TBI Dose De-escalation for Fanconi Anemia

    Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 83 participants Est. completion 2020-10-09 1 site Stand-alone
    Other conditions: Fanconi Anemia
    View official trial listing →
  • Completed NCT NCT00353301

    Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma

    Not yet reported University of Colorado, Denver 25 participants Est. completion 2012-03 1 site Stand-alone
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00355862

    Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma

    Not yet reported University of Regensburg 525 participants Est. completion 2014-05 1 site Stand-alone
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Terminated NCT NCT00358657

    Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerous Inherited Disorders

    Not yet reported Fred Hutchinson Cancer Center 14 participants Est. completion 2019-05-25 3 sites Stand-alone
    Other conditions: Immunodeficiency Syndrome, Severe Aplastic Anemia, Genetic Disorder
    View official trial listing →
  • Completed NCT NCT00363051

    Safety/Efficacy of Everolimus in Adults With Advanced Pancreatic Neuroendocrine Cancer Not Responsive to Chemotherapy

    Not yet reported Novartis Pharmaceuticals 160 participants Est. completion 2012-04 54 sites
    Other conditions: Islet Cell Carcinoma, Neuroendocrine Carcinoma, Neuroendocrine Tumor, Pancreatic Neoplasms
    View official trial listing →
  • Completed NCT NCT00365846

    "A Pilot Study to Determine the Safety of Campath-1H (Anti-CD52) Therapy in Primary Renal Allograft Transplantation"

    Not yet reported University of Wisconsin, Madison 29 participants Est. completion 2006-07 1 site Stand-alone
    Other conditions: Renal Transplant
    View official trial listing →
  • Completed NCT NCT00368914

    Sirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 30 participants Est. completion 2009-06 1 site
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00369161

    A Twelve-month, Multicenter, Open-label, Randomized Study of the Safety, Tolerability and Efficacy of Everolimus With Basiliximab, Corticosteroids and Two Different Exposure Levels of Tacrolimus in de Novo Renal Transplant Recipients

    Not yet reported Novartis 228 participants Est. completion 2008-12 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00369382

    Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 121 participants Est. completion 2010-05 23 sites Stand-alone
    Other conditions: Graft Rejection, Kidney Failure
    View official trial listing →
  • Terminated NCT NCT00373815

    Everolimus in Combination With Cyclosporine A and Prednisolone for the Treatment of Graft Versus Host Disease

    Not yet reported University Hospital Tuebingen 10 participants Est. completion 2009-10 1 site
    Other conditions: Graft Versus Host Disease
    View official trial listing →
  • Completed NCT NCT00374140

    Phase II Trial of RAD001 (Everolimus) in Previously Treated Small Cell Lung Cancer

    Not yet reported Ahmad Tarhini 40 participants Est. completion 2012-06 19 sites
    Other conditions: Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT00374647

    Study to Evaluate Safety and Efficacy of Early Calcineurin Inhibitor Withdrawal in Primary Renal Allografts

    Not yet reported University of Cincinnati 17 participants Est. completion 2007-12 2 sites
    Other conditions: Primary Renal Allograft
    View official trial listing →
  • Completed NCT NCT00375245

    Rapamycin With Grapefruit Juice for Advanced Malignancies

    Not yet reported University of Chicago 41 participants Est. completion 2012-05 1 site Stand-alone
    Other conditions: Tumors, Neoplasm Metastasis
    View official trial listing →
  • Completed NCT NCT00376688

    Temsirolimus in Treating Patients With Locally Advanced or Metastatic Breast Cancer

    Not yet reported National Cancer Institute (NCI) 31 participants Est. completion 2019-12-16 2 sites
    Other conditions: Recurrent Breast Carcinoma, Stage III Breast Cancer AJCC v7, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Stage IV Breast Cancer AJCC v6 and v7
    View official trial listing →
  • Status unknown NCT NCT00376870

    PIoglitazone for PrEvention of Restenosis in Diabetic Patients

    Not yet reported University of Rome Tor Vergata 160 participants Est. completion 2011-04 2 sites
    Other conditions: Coronary Atherosclerosis, Coronary Restenosis, Diabetes
    View official trial listing →
  • Completed NCT NCT00377962

    Nordic Everolimus (Certican) Trial in Heart and Lung Transplantation

    Not yet reported Novartis Pharmaceuticals 282 participants Est. completion 2010-02 6 sites
    Other conditions: Disorder Related to Cardiac Transplantation
    View official trial listing →
  • Completed NCT NCT00378014

    Preservation of Renal Function in Liver Transplant Recipients With Certican Therapy

    Not yet reported Novartis Pharmaceuticals 276 participants Est. completion 2013-01 16 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Completed NCT NCT00378612

    ACROSS-Cypher Total Occlusion Study of Coronary Arteries 4 Trial

    Not yet reported Sunil Rao 200 participants Est. completion 2012-09 16 sites Stand-alone
    Other conditions: Coronary Occlusions
    View official trial listing →
  • Completed NCT NCT00378703

    Bevacizumab, Sorafenib Tosylate, and Temsirolimus in Treating Patients With Metastatic Kidney Cancer

    Not yet reported National Cancer Institute (NCI) 361 participants Est. completion 2017-03-21 559 sites
    Other conditions: Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v7
    View official trial listing →
  • Completed NCT NCT00381420

    The Study of the BX Velocity Stent in the Treatment of De Novo Artery Lesions.

    Not yet reported Cordis US Corp. 100 participants Est. completion 2008-06 Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00382109

    Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission

    Not yet reported Children's Oncology Group 146 participants Est. completion 2017-06-30 50 sites Stand-alone
    Other conditions: B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Graft Versus Host Disease, L1 Childhood Acute Lymphoblastic Leukemia, L2 Childhood Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00384969

    Sorafenib and RAD001 Renal Cell Carcinoma

    Not yet reported University of California, San Francisco 21 participants Est. completion 2014-03 1 site
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00387400

    Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme

    Not yet reported NCIC Clinical Trials Group 32 participants Est. completion 2012-01-06 9 sites
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Completed NCT NCT00389220

    Limus Eluted From A Durable Versus ERodable Stent Coating

    Not yet reported Biosensors Europe SA 1707 participants Est. completion 2012-06 10 sites
    Other conditions: Coronary Disease, Coronary Stenosis
    View official trial listing →
  • Status unknown NCT NCT00390195

    Randomized Phase I/II of RAD001 in Advanced Hepatocellular Carcinoma (HCC)

    Not yet reported, Not yet reported National Health Research Institutes, Taiwan 134 participants Est. completion 2011-06 2 sites
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Terminated NCT NCT00390364

    Everolimus in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Previous Therapy

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 1 participants Est. completion 2007-10 1 site
    Other conditions: Colorectal Cancer
    View official trial listing →
  • Completed NCT NCT00392821

    Dosing and Effectiveness Study of Sorafenib and RAD001 in the Treatment of Patients With Advanced Kidney Cancer

    Not yet reported, Not yet reported SCRI Development Innovations, LLC 78 participants Est. completion 2013-10 11 sites
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT00392951

    Sirolimus for Autoimmune Disease of Blood Cells

    Not yet reported, Not yet reported Children's Hospital of Philadelphia 30 participants Est. completion 2016-02 1 site Stand-alone
    Other conditions: Autoimmune Pancytopenia, Autoimmune Lymphoproliferative Syndrome (ALPS), Evans Syndrome, Idiopathic Thrombocytopenic Purpura, Anemia, Hemolytic, Autoimmune, Autoimmune Neutropenia, Lupus Erythematosus, Systemic, Inflammatory Bowel Disease, Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00396721

    Sirolimus Therapy for Poor Prognosis Immunoglobulin A Nephropathy

    Not yet reported Josep m Cruzado 23 participants Est. completion 2010-02 1 site Stand-alone
    Other conditions: Glomerulonephritis, IGA, Nephropathy, IGA, IGA Nephropathy
    View official trial listing →
  • Completed NCT NCT00397982

    Temsirolimus and Bevacizumab in Treating Patients With Stage III or Stage IV Malignant Melanoma

    Not yet reported National Cancer Institute (NCI) 17 participants Est. completion 2013-07 2 sites
    Other conditions: Recurrent Melanoma, Stage IIIB Skin Melanoma, Stage IIIC Skin Melanoma, Stage IV Skin Melanoma
    View official trial listing →
  • Completed NCT NCT00398515

    Lenalidomide and Temsirolimus in Treating Patients With Previously Treated Multiple Myeloma

    Not yet reported National Cancer Institute (NCI) 25 participants 1 site
    Other conditions: Refractory Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00401115

    Safety and Tolerability of MS-R001 in Patients With Diabetic Macular Edema Secondary to Diabetic Retinopathy

    Not yet reported Santen Inc. 50 participants Est. completion 2008-06 2 sites
    Other conditions: Diabetic Macular Edema, Diabetic Retinopathy
    View official trial listing →
  • Completed NCT NCT00401778

    Trial of RAD001 in Patients With Operable Non-Small Cell Lung Cancer (NSCLC)

    Not yet reported Emory University 33 participants Est. completion 2013-12 1 site
    Other conditions: Lung Cancer
    View official trial listing →
  • Terminated NCT NCT00402415

    Study of Combination of Sirolimus and Sutent in Patients With Advanced Solid Tumors Non-Curable With Standard Therapy

    Not yet reported Yale University 18 participants Est. completion 2008-07 1 site
    Other conditions: Tumors
    View official trial listing →
  • Completed NCT NCT00402532

    Immunosuppressive Therapy With Certican (Everolimus) After Lung Transplantation

    Not yet reported Hannover Medical School 190 participants Est. completion 2011-12 1 site
    Other conditions: Lung Transplantation
    View official trial listing →
  • Completed NCT NCT00402636

    Rapamycin+Estradiol- vs. Rapamycin-Eluting Stents to Reduce Restenosis (ISAR-PEACE)

    Not yet reported Deutsches Herzzentrum Muenchen 502 participants Est. completion 2006-10 2 sites
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Terminated NCT NCT00402662

    A Study of Everolimus in Combination With Imatinib in Metastatic Melanoma

    Not yet reported Yale University 3 participants Est. completion 2006-06 1 site
    Other conditions: Metastatic Melanoma
    View official trial listing →
  • Completed NCT NCT00403338

    The Impact of Stent Deployment Techniques on Clinical Outcomes of Patient Treated With the CYPHER® Stent (S.T.L.L.R.)

    Cordis US Corp. 1500 participants Est. completion 2006-04
    Other conditions: Coronary Stenosis
    View official trial listing →
  • Terminated NCT NCT00406276

    Phase I/II Trial of RAD001 Plus Docetaxel in Patients With Metastatic or Recurrent Non-Small Cell Lung Cancer

    Not yet reported, Not yet reported Emory University 28 participants Est. completion 2013-02 1 site
    Other conditions: Lung Cancer
    View official trial listing →
  • Completed NCT NCT00406393

    Sirolimus/Tacrolimus Versus Tacrolimus/Methotrexate for Preventing Graft-Versus-Host Disease (GVHD) (BMT CTN 0402)

    Not yet reported Medical College of Wisconsin 304 participants Est. completion 2015-10 24 sites Stand-alone
    Other conditions: Leukemia, Myelocytic, Acute, Leukemia, Lymphocytic, Acute, Leukemia, Myeloid, Chronic, Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00408655

    Temsirolimus, Carboplatin, and Paclitaxel in Treating Patients With Advanced Solid Tumors

    Not yet reported National Cancer Institute (NCI) 38 participants 1 site
    Other conditions: Ovarian Sarcoma, Ovarian Stromal Cancer, Recurrent Endometrial Carcinoma, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Stage III Endometrial Carcinoma, Stage III Ovarian Epithelial Cancer, Stage III Ovarian Germ Cell Tumor, Stage IV Endometrial Carcinoma, Stage IV Ovarian Epithelial Cancer, Stage IV Ovarian Germ Cell Tumor, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00409292

    RAD001 in Previously Treated Patients With Metastatic Pancreatic Cancer

    Not yet reported Dana-Farber Cancer Institute 33 participants Est. completion 2009-05 3 sites
    Other conditions: Pancreatic Cancer
    View official trial listing →
  • Terminated NCT NCT00409461

    Comparison of Sirolimus Alone With Sirolimus Plus Tacrolimus in Type 1 Diabetic Recipients of Cultured Islet Cell Grafts

    Not yet reported Universitair Ziekenhuis Brussel 2 sites
    Other conditions: Islet Transplantation, Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT00409994

    Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer

    Not yet reported, Not yet reported Maastricht Radiation Oncology 44 participants Est. completion 2018-12 1 site
    Other conditions: Rectum Cancer
    View official trial listing →
  • Completed NCT NCT00410124

    RAD001 Plus Best Supportive Care (BSC) Versus BSC Plus Placebo in Patients With Metastatic Carcinoma of the Kidney Which Has Progressed After Treatment With Sorafenib and/or Sunitinib

    Not yet reported Novartis Pharmaceuticals 416 participants Est. completion 2011-10 93 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00411619

    Everolimus (RAD001) Therapy of Giant Cell Astrocytoma in Patients With Tuberous Sclerosis Complex

    Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 28 participants Est. completion 2014-01 1 site
    Other conditions: Tuberous Sclerosis, Subependymal Giant Cell Astrocytoma
    View official trial listing →
  • Completed NCT NCT00411788

    A Phase II Study of Rapamycin and Trastuzumab for Patients With HER-2 Receptor Positive Metastatic Breast Cancer

    Not yet reported Yale University 11 participants Est. completion 2010-05 2 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00412061

    Everolimus and Octreotide in Patients With Advanced Carcinoid Tumor

    Not yet reported Novartis Pharmaceuticals 429 participants Est. completion 2013-06 70 sites
    Other conditions: Carcinoid Tumor, Malignant Carcinoid Syndrome
    View official trial listing →
  • Completed NCT NCT00414440

    Efficacy, Safety and Tolerability of Everolimus in Preventing End-stage Renal Disease in Patients With Autosomal Dominant Polycystic Kidney Disease

    Not yet reported Novartis Pharmaceuticals 431 participants Est. completion 2013-10 24 sites
    Other conditions: Autosomal Dominant Polycystic Kidney Disease
    View official trial listing →
  • Completed NCT NCT00414648

    Efficacy and Safety of Sirolimus in LAM

    Not yet reported University of Cincinnati 89 participants Est. completion 2011-02 13 sites Stand-alone
    Other conditions: Lymphangioleiomyomatosis
    View official trial listing →
  • Terminated NCT NCT00417677

    A Study Combining Treatment With Temsirolimus and Sunitinib for Subjects With Advanced Renal Cell Carcinoma

    Not yet reported, Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 124 participants Est. completion 2007-05 4 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00418067

    Zotarolimus-Eluting Stent Versus Sirolimus-Eluting Stent and PacliTaxel-Eluting Stent for Coronary Lesions

    Not yet reported Seung-Jung Park 2645 participants Est. completion 2009-01 20 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00419159

    Efficacy and Safety of Everolimus in Patients With Metastatic Colorectal Cancer Who Have Failed Prior Targeted Therapy and Chemotherapy

    Not yet reported Novartis Pharmaceuticals 199 participants Est. completion 2009-03 1 site
    Other conditions: Colorectal Cancer
    View official trial listing →
  • Terminated NCT NCT00420537

    Shift to Everolimus (RAD) Kidney Sparing Study

    Not yet reported University of Bologna 34 participants Est. completion 2009-03 1 site
    Other conditions: Kidney Dysfunction, Heart Transplantation
    View official trial listing →
  • Completed NCT NCT00422344

    A Study of RAD001 and Sunitinib in Metastatic Renal Cell Carcinoma

    Not yet reported Memorial Sloan Kettering Cancer Center 20 participants Est. completion 2010-02 1 site
    Other conditions: Renal Cell Carcinoma, Kidney Cancer
    View official trial listing →
  • Terminated NCT NCT00422565

    Zotarolimus-Versus Sirolimus-Versus PacliTaxel-Eluting Stent for Acute Myocardial Infarction Patients

    Not yet reported Seung-Jung Park 328 participants Est. completion 2008-09 12 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00422968

    Bypass Surgery Versus Angioplasty Using Sirolimus-Eluting Stent in Patients With Left Main Coronary Artery Disease

    Not yet reported Seung-Jung Park 1454 participants Est. completion 2013-12 13 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00423865

    Cisplatin and Everolimus in Treating Patients With Advanced Solid Tumors

    Not yet reported Memorial Sloan Kettering Cancer Center 30 participants Est. completion 2011-09 1 site
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00425308

    Efficacy and Safety of Everolimus in Combination With Cyclosporine Microemulsion Versus Everolimus in Combination With Enteric-coated Mycophenolate Sodium (EC-MPS), in Adult Renal Transplant Patients in Maintenance.

    Not yet reported Novartis Pharmaceuticals 30 participants 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Status unknown NCT NCT00426049

    Systemic Treatment With Everolimus for the Prevention of MACE After Bare Metal Stent Implantation

    Not yet reported German Heart Institute 484 participants 1 site
    Cardiovascular disease Other conditions: Coronary Restenosis
    View official trial listing →
  • Completed NCT NCT00426517

    Donor Stem Cell Transplantation for Congenital Immunodeficiencies

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 48 participants Est. completion 2019-11-01 1 site Stand-alone
    Other conditions: Inherited Immune Deficiencies
    View official trial listing →
  • Completed NCT NCT00426530

    Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer

    Not yet reported Novartis Pharmaceuticals 50 participants Est. completion 2010-06 6 sites
    Other conditions: Breast Neoplasms, Neoplasm Metastasis
    View official trial listing →
  • Completed NCT NCT00426556

    Efficacy and Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer

    Not yet reported Novartis Pharmaceuticals 88 participants Est. completion 2014-03 20 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT00428064

    Study Evaluating Sirolimus and Cyclosporine in Kidney Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 408 participants Est. completion 2004-06
    Other conditions: Renal Transplantation
    View official trial listing →
  • Terminated NCT NCT00429052

    Mechanism of Percutaneous Revascularization for Coronary Bifurcation Disease

    University of Florida 24 participants Est. completion 2008-09 1 site
    Other conditions: Coronary Disease
    View official trial listing →
  • Completed NCT NCT00429793

    Temsirolimus in Treating Patients With Refractory or Recurrent Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer

    Not yet reported National Cancer Institute (NCI) 60 participants Est. completion 2012-01 1 site
    Other conditions: Fallopian Tube Cancer, Primary Peritoneal Cavity Cancer, Recurrent Ovarian Epithelial Cancer
    View official trial listing →
  • Completed NCT NCT00433485

    Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants

    Not yet reported Yale University 16 participants Est. completion 2008-03
    Other conditions: Neoplastic Syndrome, Non-melanomatous Skin Cancer
    View official trial listing →
  • Completed NCT NCT00434174

    Safety of Everolimus and Pemetrexed in Lung Cancer Patients

    Not yet reported Novartis Pharmaceuticals 48 participants Est. completion 2010-12 5 sites
    Other conditions: Non Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT00434811

    Islet Transplantation in Type 1 Diabetes

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 48 participants Est. completion 2014-05 8 sites Stand-alone
    Other conditions: Type 1 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00434850

    Peritransplant Deoxyspergualin in Islet Transplantation in Type 1 Diabetes

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 14 participants Est. completion 2013-11 3 sites Stand-alone
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT00436618

    Everolimus in Treating Patients With Lymphoma That Has Relapsed or Not Responded to Previous Treatment

    Not yet reported Mayo Clinic 277 participants Est. completion 2019-10-09 3 sites
    Other conditions: Leukemia, Lymphoma, Lymphoproliferative Disorder
    View official trial listing →
  • Completed NCT NCT00438919

    A Multi-center Post-Market Surveillance Registry

    Not yet reported Cordis US Corp. 15000 participants Est. completion 2009-12 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00443937

    Pharmacokinetics of Everolimus and Enteric-Coated Mycophenolatesodium Before and After Withdrawal of Cyclosporine in Renal Transplant Patients

    Not yet reported Charite University, Berlin, Germany 15 participants Est. completion 2006-03 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00446264

    Islet Allotransplantation With Steroid Free Immunosuppression

    Not yet reported University Hospital, Lille 14 participants Est. completion 2009-02 1 site Stand-alone
    Other conditions: Type 1 Diabetes, Hypoglycemia, Metabolic Diseases
    View official trial listing →
  • Completed NCT NCT00446368

    Safety Study of RAD001 to Treat Patients With Metastatic Kidney Cancer

    Not yet reported The Methodist Hospital Research Institute 66 participants Est. completion 2008-10 1 site
    Other conditions: Carcinoma, Renal Cell
    View official trial listing →
  • Completed NCT NCT00448149

    Phase I/II Trial of RAD001 Plus Nexavar in Patients With Kidney Cancer

    Not yet reported, Not yet reported The Methodist Hospital Research Institute 55 participants Est. completion 2009-06 1 site
    Other conditions: Carcinoma, Renal Cell
    View official trial listing →
  • Completed NCT NCT00449280

    Drug Interaction Study of Sorafenib and Rapamycin in Advanced Malignancies

    Not yet reported University of Chicago 34 participants Est. completion 2009-09 1 site
    Other conditions: Advanced Solid Tumor
    View official trial listing →
  • Completed NCT NCT00449748

    Everolimus (RAD001) as Therapy for Patients With Systemic Mastocytosis

    Not yet reported M.D. Anderson Cancer Center 10 participants Est. completion 2009-10 1 site
    Other conditions: Systemic Mastocytosis
    View official trial listing →
  • Completed NCT NCT00450320

    Sirolimus in Treating Patients With HIV-Related Kaposi's Sarcoma

    Not yet reported AIDS Malignancy Consortium 7 participants Est. completion 2009-09 3 sites
    Other conditions: Sarcoma
    View official trial listing →
  • Terminated NCT NCT00452361

    Study Evaluating of Calcineurin Inhibitors Versus Sirolimus in Renal Allograft Recipient

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 31 participants Est. completion 2008-08 1 site Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00452517

    Comparison of Stent Graft, Sirolimus Stent, and Bare Metal Stent Implanted in Patients With Acute Coronary Syndrome

    Not yet reported University of Zagreb 100 participants Est. completion 2004-11 1 site
    Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Completed NCT NCT00455013

    A Phase II Study of Belatacept (BMS-224818) With a Steroid-free Regimen in Subjects Undergoing Kidney Transplantation

    Not yet reported Bristol-Myers Squibb 93 participants Est. completion 2012-08 17 sites Stand-alone
    Other conditions: Disorder Related to Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00456833

    Combination of RAD001 and Erlotinib in Patients With Advanced Non Small Cell Lung Cancer Previously Treated Only With Chemotherapy

    Not yet reported Novartis Pharmaceuticals 248 participants 14 sites
    Other conditions: Non Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT00457119

    Combination of RAD001 With Carboplatin, Paclitaxel and Bevacizumab in Non-small-cell Lung Cancer (NSCLC) Patients

    Not yet reported Novartis Pharmaceuticals 69 participants Est. completion 2009-11 8 sites
    Other conditions: Non Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT00457808

    Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM

    Not yet reported Children's Hospital Medical Center, Cincinnati 25 participants Est. completion 2006-03 1 site
    Other conditions: Tuberous Sclerosis, Lymphangioleiomyomatosis
    View official trial listing →
  • Completed NCT NCT00457964

    RAD001 Therapy of Angiomyolipomata in Patients With TS Complex and Sporadic LAM

    Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 36 participants Est. completion 2013-07 1 site
    Other conditions: Tuberous Sclerosis, Lymphangioleiomyomatosis
    View official trial listing →
  • Completed NCT NCT00458237

    Dose Escalation Followed by Study of RAD001 in Combination With Trastuzumab in HER2-Positive Metastatic Breast Cancer

    Not yet reported, Not yet reported Beth Israel Deaconess Medical Center 11 participants Est. completion 2010-04 2 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00459186

    The Use of RAD001 With Docetaxel in the Treatment of Metastatic, Androgen Independent Prostate Cancer

    Not yet reported, Not yet reported Dana-Farber Cancer Institute 19 participants Est. completion 2012-12 5 sites
    Other conditions: Metastatic, Androgen Independent Prostate Cancer, Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT00461357

    Sirolimus Based Immunosuppression for Patients Undergoing Kidney Transplantation in the Eurotransplant Senior Program

    Medical University of Vienna 48 participants Est. completion 2007-12
    Other conditions: Kidney Function After Transplantation, Outcome After Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00464399

    Feasibility and Safety of Early Switch to Everolimus From Cyclosporine in de Novo Renal Transplant Patients

    Not yet reported Novartis Pharmaceuticals 20 participants 1 site
    Other conditions: De Novo Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00464555

    Strategies to Improve Islet Survival

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 5 participants Est. completion 2014-02 2 sites Stand-alone
    Other conditions: Type 1 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00466466

    Safety of RAD001 in Combination With Cisplatin and Etoposide in Lung Cancer Patients

    Not yet reported Novartis Pharmaceuticals 20 participants 6 sites
    Other conditions: Small-Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT00467194

    Sirolimus and Bevacizumab in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

    Not yet reported National Cancer Centre, Singapore 27 participants 2 sites
    Other conditions: Liver Cancer
    View official trial listing →
  • Terminated NCT NCT00468442

    B-Lymphocyte Immunotherapy in Islet Transplantation

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 2 participants Est. completion 2011-09 1 site Stand-alone
    Other conditions: Type 1 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00470665

    Study Comparing Sirolimus/Prograf vs Sirolimus/CsA in High-Risk Renal Transplant Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 460 participants Est. completion 2004-07
    Other conditions: Renal Allograft Recipients
    View official trial listing →
  • Terminated NCT NCT00473005

    Phase I Oral mTOR Inhibitor RAD001 in Combo w/ Capecitabine for Metastatic Breast

    Not yet reported Stanford University 18 participants Est. completion 2011-12 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00473499

    PEPCAD III Substudy: Stem Cell Mobilization

    Not yet reported, Not yet reported University Hospital, Saarland 60 participants Est. completion 2009-11 1 site
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT00473551

    Anti-Third Party T Lymphocytes With Nonmyeloablative Stem Cell Transplantation for Indolent Lymphoid Malignancies

    Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2009-11 1 site Stand-alone
    Other conditions: Leukemia, Lymphoma, Myeloma
    View official trial listing →
  • Completed NCT NCT00473772

    DEBlue Stent vs Cypher Stent in the Treatment of Advanced Coronary Artery Disease

    Not yet reported, Not yet reported University Hospital, Saarland 643 participants Est. completion 2011-01 16 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00474786

    Temsirolimus Versus Sorafenib As Second-Line Therapy In Patients With Advanced RCC Who Have Failed First-Line Sunitinib

    Not yet reported Pfizer 512 participants Est. completion 2013-01 128 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00474929

    Sorafenib and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

    Not yet reported, Not yet reported Mayo Clinic 103 participants Est. completion 2019-08-08 2 sites
    Other conditions: Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
    View official trial listing →
  • Completed NCT NCT00476957

    Randomized Study Comparing Endeavor With Cypher Stents (PROTECT)

    Not yet reported Medtronic Vascular 8709 participants Est. completion 2014-07 1 site
    Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Completed NCT NCT00478608

    Study Evaluating Rapamune® Maintenance Regimen

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 79 participants Est. completion 2008-11 9 sites
    Other conditions: Renal Transplant
    View official trial listing →
  • Completed NCT NCT00478634

    A Phase 1 Study Investigating the Combination of RAD001, Cetuximab and Irinotecan as Second-line Therapy After FOLFOX (or XELOX) Plus Bevacizumab in Patients With Metastatic Colorectal Cancer

    Not yet reported Novartis Pharmaceuticals 19 participants Est. completion 2009-09 16 sites
    Other conditions: Colorectal Cancer, Colorectal Carcinoma, Colorectal Tumors, Neoplasms, Colorectal
    View official trial listing →
  • Completed NCT NCT00482183

    Comparison Between Pioglitazone and SES With type2 DM

    Not yet reported, Not yet reported Showa University 38 participants Est. completion 2007-06
    Cardiovascular diseaseType 2 diabetes
    View official trial listing →
  • Completed NCT NCT00483262

    Combination CCI-779 (Temsirolimus) and Bortezomib (Velcade) in Relapsed and/or Relapsed/Refractory Multiple Myeloma

    Not yet reported, Not yet reported Dana-Farber Cancer Institute 63 participants Est. completion 2012-02 3 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00484094

    Study Investigating Rapamune For Post-Marketing Surveillance

    Pfizer 209 participants Est. completion 2015-06 11 sites
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00485004

    Focal In-stent Restenosis After Drug-Eluting Stent

    Not yet reported Seung-Jung Park 100 participants Est. completion 2011-03 15 sites Stand-alone
    Other conditions: In Stent Restenosis
    View official trial listing →
  • Completed NCT NCT00485030

    Diffuse Type In-Stent Restenosis After Drug-Eluting Stent

    Not yet reported Seung-Jung Park 60 participants Est. completion 2011-10 15 sites Stand-alone
    Other conditions: In-stent Restenosis
    View official trial listing →
  • Terminated NCT NCT00489164

    Feasibility Study With the Sirolimus-Eluting BX Velocity Balloon-Expandable Stent in the Treatment of Diabetic Patients With Native Coronary Artery Lesions

    Not yet reported, Not yet reported Cordis US Corp. 83 participants Est. completion 2004-05 11 sites
    Other conditions: Peripheral Vascular Diseases
    View official trial listing →
  • Terminated NCT NCT00489281

    Non-Myeloablative Bone Marrow Transplant for Patients With Sickle Cell Anemia and Other Blood Disorders

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 43 participants Est. completion 2018-12-29 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Status unknown NCT NCT00490789

    Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM

    Not yet reported Cardiff University 14 participants Est. completion 2009-09 3 sites
    Other conditions: Tuberous Sclerosis, Lymphangioleiomyomatosis
    View official trial listing →
  • Completed NCT NCT00491517

    Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety

    Not yet reported Mario Negri Institute for Pharmacological Research 22 participants Est. completion 2009-08 1 site Stand-alone
    Other conditions: Polycystic Kidney
    View official trial listing →
  • Status unknown NCT NCT00493194

    Fibrosis in Renal Allografts

    Not yet reported University Hospital, Antwerp 100 participants Est. completion 2007-07 3 sites
    Other conditions: Kidney Failure, Chronic, Transplantation, Immunosuppression, Interstitial Fibrosis
    View official trial listing →
  • Completed NCT NCT00494091

    Study Evaluating The Safety, Efficacy & Pharmacokinetics Of Temsirolimus(CCI-779) In Subjects With Advanced Renal Cell Carcinoma

    Not yet reported Pfizer 82 participants Est. completion 2012-03 24 sites
    Other conditions: Advanced Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00495898

    A Study of Diabetic Patients With De Novo Native Coronary Artery Lesions

    Not yet reported Cordis US Corp. 200 participants Est. completion 2009-11 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00496600

    Phase I Study of Patupilone and RAD001

    Not yet reported University of Medicine and Dentistry of New Jersey 42 participants Est. completion 2011-02 1 site
    Other conditions: Refractory Malignancy
    View official trial listing →
  • Completed NCT NCT00497172

    Diabetes Drug Eluting Sirolimus Stent Experience in Restenosis Trial

    Not yet reported Cordis US Corp. 150 participants Est. completion 2009-04 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00498966

    Ph II Study of Perifosine for Patients With Carcinoma of the Kidney

    Not yet reported AEterna Zentaris 50 participants Est. completion 2011-10 3 sites
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT00499486

    Sirolimus in Treating Patients With Advanced Pancreatic Cancer

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 47 participants Est. completion 2009-06 1 site Stand-alone
    Other conditions: Pancreatic Cancer
    View official trial listing →
  • Status unknown NCT NCT00499603

    Paclitaxel Followed by FEC Versus Paclitaxel and RAD001 Followed by FEC In Women With Breast Cancer

    Not yet reported M.D. Anderson Cancer Center 62 participants Est. completion 2017-04 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00502242

    Study Evaluating The Effect Of Ramipril On Urinary Protein Excretion In Renal Transplant Patients Converted To Sirolimus

    Not yet reported Pfizer 229 participants Est. completion 2013-09 49 sites
    Other conditions: Kidney Transplant
    View official trial listing →
  • Status unknown NCT NCT00505102

    Safe Renal Function In Long Term Heart Transplanted Patients

    Not yet reported A.O. Ospedale Papa Giovanni XXIII 200 participants Est. completion 2009-07 2 sites
    Other conditions: Kidney Diseases, Heart Transplantation
    View official trial listing →
  • Terminated NCT NCT00506948

    Thymoglobulin, Sirolimus and Mycophenolate Mofetil for Prevention of Acute Graft-Versus-Host Disease (GVHD)

    Not yet reported M.D. Anderson Cancer Center 13 participants Est. completion 2010-10 1 site Stand-alone
    Other conditions: Hematological Malignancies, Myelodysplastic Syndrome, Leukemia, Lymphoma
    View official trial listing →
  • Completed NCT NCT00507793

    Study Evaluating the Efficacy and Safety of Cyclosporine Reduction in Kidney Transplant Recipients Receiving Sirolimus

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 385 participants Est. completion 2002-06
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00509431

    Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma

    Not yet reported Jonsson Comprehensive Cancer Center 19 participants Est. completion 2012-09 1 site Stand-alone
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Completed NCT NCT00509613

    Phase 1 Study With Sorafenib and Sirolimus

    Not yet reported Radboud University Medical Center 1 site
    Other conditions: Advanced Solid Tumor, Refractory to Standard Therapies
    View official trial listing →
  • Completed NCT NCT00510068

    Efficacy and Safety of Everolimus (RAD001) Compared to Placebo in Patients With Advanced Neuroendocrine Tumors

    Not yet reported Novartis Pharmaceuticals 410 participants Est. completion 2014-03 82 sites
    Other conditions: Advanced Neuroendocrine Tumors of Pancreatic Origin
    View official trial listing →
  • Terminated NCT NCT00512668

    Hormone Therapy and Temsirolimus in Treating Patients With Relapsed Prostate Cancer

    Not yet reported National Cancer Institute (NCI) 24 participants 1 site
    Other conditions: Adenocarcinoma of the Prostate, Recurrent Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00513474

    Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant

    Not yet reported Massachusetts General Hospital 46 participants Est. completion 2013-02-12 1 site Stand-alone
    Other conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
    View official trial listing →
  • Completed NCT NCT00514514

    Study Investigating a Standard Regimen in de Novo Kidney Transplant Patients Versus a Calcineurin Inhibitor (CNI)-Free Regimen and a CNI-low Dose Regimen

    Not yet reported Novartis Pharmaceuticals 802 participants Est. completion 2015-06 18 sites
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Terminated NCT NCT00515086

    Study of Everolimus (RAD001) in Patients With Recurrent Glioblastoma Multiforme (GBM)

    Not yet reported Novartis Pharmaceuticals 41 participants Est. completion 2009-08 8 sites
    Other conditions: Glioblastoma Multiforme
    View official trial listing →
  • Completed NCT NCT00516165

    RAD001 in Advanced Hepatocellular Carcinoma

    Not yet reported, Not yet reported Massachusetts General Hospital 28 participants Est. completion 2011-11 3 sites
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT00518271

    Study Comparing Standard Dose and Reduced Dose Tacrolimus + Sirolimus + Corticosteroids in Renal Allograft Recipients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 120 participants Est. completion 2002-06
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00518375

    Study Comparing Graft Function in Renal Allograft Recepients Receiving Reduced or Standard Dose CsA With Sirolimus

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 250 participants Est. completion 2001-05
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00519116

    Study Comparing Standard Dose and Reduced Dose Tacrolimus With Sirolimus in Renal Transplant Patients

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 150 participants Est. completion 2001-08
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00519324

    Efficacy and Safety of Everolimus (RAD001) in Patients With Advanced Gastric Cancer

    Not yet reported Novartis Pharmaceuticals 54 participants 8 sites
    Other conditions: Advanced Gastric Cancer
    View official trial listing →
  • Completed NCT NCT00520130

    Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune System

    Not yet reported, Not yet reported National Cancer Institute (NCI) 92 participants Est. completion 2018-12-31 1 site Stand-alone
    Other conditions: Myelodysplastic Syndrome, Hodgkin's Lymphoma, Non-Hodgkin's Disease, Acute Leukemia, Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00521001

    Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by Surgery

    Not yet reported Alliance for Clinical Trials in Oncology 49 participants Est. completion 2010-12 198 sites
    Other conditions: Melanoma (Skin)
    View official trial listing →
  • Completed NCT NCT00522665

    Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer

    Not yet reported, Not yet reported Hoosier Cancer Research Network 41 participants Est. completion 2015-02 14 sites
    Other conditions: Colorectal Cancer
    View official trial listing →
  • Completed NCT NCT00523432

    A Phase I Study of CCI-779 (Temsirolimus) in Combination With Topotecan in Patients With Gynecologic Malignancies

    Not yet reported University of Chicago 15 participants Est. completion 2010-12 1 site
    Other conditions: Genital Neoplasms, Female
    View official trial listing →
  • Completed NCT NCT00525889

    Proleukin and Rapamune in Type 1 Diabetes

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 9 participants Est. completion 2013-09 3 sites Stand-alone
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Terminated NCT NCT00526591

    Everolimus in Treating Patients With Newly Diagnosed Localized Prostate Cancer

    Not yet reported Jorge A. Garcia, MD 17 participants Est. completion 2011-08 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00529802

    Exploratory Study Evaluating Fluorodeoxyglucose - Position Emission Tomography as a Predictive Marker for Therapy With RAD001 in Metastatic Renal Cell Cancer

    Not yet reported University of Chicago 60 participants Est. completion 2010-07 5 sites
    Other conditions: Carcinoma, Renal Cell
    View official trial listing →
  • Completed NCT NCT00531063

    This is a Two-year Follow-up Study to Evaluate the Long-term Safety, Tolerability and Efficacy of 2 Different Doses of Everolimus

    Not yet reported Novartis Pharmaceuticals 237 participants 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00531440

    This is a 2-year Follow-up Study to Evaluate the Long-term Effects in Patients Who Completed the Study CRAD001A2307.

    Not yet reported Novartis Pharmaceuticals 256 participants 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Active, not recruiting NCT NCT00544115

    Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

    Not yet reported City of Hope Medical Center 260 participants Est. completion 2027-03-29
    Other conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Precancerous/Nonmalignant Condition
    View official trial listing →
  • Status unknown NCT NCT00544999

    Everolimus, Cytarabine, and Daunorubicin in Treating Patients With Relapsed Acute Myeloid Leukemia

    Not yet reported Institut de Recherche Clinique sur les Cancers et le Sang 21 participants 1 site
    Other conditions: Leukemia
    View official trial listing →
  • Terminated NCT NCT00548717

    Sirolimus, Mycophenolate Mofetil and Bortezomib as Graft-Versus-Host Disease (GVHD) Prophylaxis After Reduced Intensity Conditioning (RIC) Hematopoietic Stem Cell Transplantation

    Not yet reported Dana-Farber Cancer Institute 15 participants Est. completion 2013-09 1 site Stand-alone
    Other conditions: Graft-vs-Host Disease
    View official trial listing →
  • Status unknown NCT NCT00552656

    Long Term Efficacy and Safety of Firebird Sirolimus-Eluting Stent In Complex Coronary Lesions

    Xijing Hospital 1000 participants Est. completion 2010-08 1 site
    Other conditions: Coronary Disease
    View official trial listing →
  • Completed NCT NCT00552669

    Study of Oral Rapamycin Plus Bare Metal Stents vs Drug Eltuting Stents

    Not yet reported Centro de estudios en Cardiologia Intervencionista 200 participants Est. completion 2007-09 3 sites Stand-alone
    Other conditions: Coronary Heart Disease, Coronary Restenosis
    View official trial listing →
  • Completed NCT NCT00553150

    Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

    Not yet reported, Not yet reported Alliance for Clinical Trials in Oncology 122 participants Est. completion 2019-11-15 178 sites
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Status unknown NCT NCT00554125

    Sirolimus-Based Immunosuppression Therapy in OLT for Patients With HCC Exceeding Milan Criteria

    Not yet reported Fudan University 220 participants Est. completion 2013-08 1 site
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT00555256

    A Phase I Study of SUNITINIB and Rapamycin in Advanced Non-Small Cell Lung Cancer (NSCLC)

    Not yet reported Washington University School of Medicine 19 participants Est. completion 2012-12 1 site
    Other conditions: Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT00555373

    Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based Immunosuppression

    Not yet reported Pediatric Nephrology of Alabama 52 participants Est. completion 2012-11 4 sites
    Other conditions: Renal Transplant
    View official trial listing →
  • Completed NCT NCT00556933

    Improved Induction and Maintenance Immunosuppression in Kidney Transplantation

    Not yet reported University of Nebraska 180 participants Est. completion 2011-06-01 1 site Stand-alone
    Other conditions: End-stage Renal Disease
    View official trial listing →
  • Completed NCT NCT00560963

    Treatment of Patients Suffering From a Progressive Pancreas Carcinoma With Everolimus (RAD001) and Gemcitabine

    Not yet reported, Not yet reported Novartis Pharmaceuticals 21 participants Est. completion 2011-01 5 sites
    Other conditions: Advanced or Metastatic Pancreatic Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT00563147

    A Phase 1b, Open-Label, Dose-Finding Study to Evaluate the Safety of Tivozanib (AV-951) in Combination With Temsirolimus in Subjects With Metastatic Renal Cell Carcinoma

    Not yet reported AVEO Pharmaceuticals, Inc. 28 participants Est. completion 2011-02 5 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00565773

    Belatacept Post Depletional Repopulation to Facilitate Tolerance

    Not yet reported Allan D Kirk, MD, PhD 40 participants Est. completion 2017-07-01 2 sites Stand-alone
    Other conditions: Organ Transplantation
    View official trial listing →
  • Completed NCT NCT00566813

    Islet Transplantation in Type 1 Diabetic Patients Using the Edmonton Protocol of Steroid Free Immunosuppression

    Not yet reported, Not yet reported University of Illinois at Chicago 10 participants Est. completion 2020-07-15 1 site
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT00567554

    Bevacizumab, Everolimus (RAD001), and Lapatinib as Neoadjuvant Chemotherapy Regimes for Primary Breast Cancer

    Not yet reported GBG Forschungs GmbH 2600 participants Est. completion 2015-10 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00570921

    Study of Combined Fulvestrant and Everolimus in Advanced/Metastatic Breast Cancer After Aromatase Inhibitor Failure

    Not yet reported Mara Chambers 33 participants Est. completion 2015-01 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00574366

    Erlotinib and Everolimus in Treating Patients With Metastatic Breast Cancer

    Not yet reported Vanderbilt-Ingram Cancer Center 14 participants Est. completion 2009-02 3 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00574769

    Safety Study & Effectiveness of Docetaxel With RAD001 and Bevacizumab in Men With Advanced Prostate Cancer

    Not yet reported, Not yet reported University of Southern California 27 participants Est. completion 2017-02-17 2 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00576680

    RAD001 and Temozolomide in Patients With Advanced Pancreatic Neuroendocrine Tumors

    Not yet reported, Not yet reported Dana-Farber Cancer Institute 43 participants Est. completion 2019-03-29 3 sites
    Other conditions: Pancreatic Neuroendocrine Tumor
    View official trial listing →
  • Completed NCT NCT00577278

    A Phase II Study of Allo-HCT for B-Cell NHL Using Zevalin, Fludarabine and Melphalan

    Not yet reported City of Hope Medical Center 41 participants Est. completion 2023-12-14 1 site Stand-alone
    Other conditions: Graft Versus Host Disease, Leukemia, Lymphoma
    View official trial listing →
  • Terminated NCT NCT00582738

    Efficacy of Everolimus as Inhibitor of Fibrosis Progression in Liver Transplant Patients With Recurrence of Hepatitis C Viral Infection

    Not yet reported Novartis Pharmaceuticals 43 participants Est. completion 2010-01 1 site
    Other conditions: Recurrent Hepatitis C
    View official trial listing →
  • Completed NCT NCT00583063

    Interaction Study of Rapamycin and Sunitinib in Patients With Advanced Cancers

    Not yet reported University of Chicago 23 participants Est. completion 2008-04 1 site
    Other conditions: Solid Tumors
    View official trial listing →
  • Completed NCT NCT00586443

    BEP Study Phase I (Bevacizumab, Everolimus, Panitumumab)

    Not yet reported Herbert Hurwitz, MD 56 participants Est. completion 2014-09 1 site
    Other conditions: Solid Tumors
    View official trial listing →
  • Completed NCT NCT00589563

    Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer

    Not yet reported City of Hope Medical Center 32 participants Est. completion 2012-02 2 sites Stand-alone
    Other conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Infection, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous Condition, Secondary Myelofibrosis, Small Intestine Cancer
    View official trial listing →
  • Completed NCT NCT00590174

    Clopidogrel Use and Long-term Safety After Drug-Eluting Stents Implantation

    Not yet reported Seung-Jung Park 1175 participants Est. completion 2010-04 20 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00591734

    RAD001 Plus Bevacizumab in Metastatic Melanoma

    Not yet reported SCRI Development Innovations, LLC 57 participants Est. completion 2011-10 15 sites
    Other conditions: Metastatic Melanoma
    View official trial listing →
  • Terminated NCT NCT00593008

    Temsirolimus in Combination With Gemcitabine in Previously Untreated Metastatic Pancreatic Cancer

    Not yet reported Massachusetts General Hospital 5 participants Est. completion 2009-10 1 site
    Other conditions: Pancreatic Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT00593060

    Temsirolimus (CCI-770, Torisel) Combined With Cetuximab in Cetuximab-Refractory Colorectal Cancer

    Not yet reported Jeffrey W. Clark, MD 35 participants Est. completion 2010-11 2 sites
    Other conditions: Colorectal Cancer, Colorectal Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT00596557

    Everolimus and Low Dose CNI Compared With MMF and Full CNI Dose in Heart Transplanted Patients: One Year Follow up

    Not yet reported Rabin Medical Center 20 participants Est. completion 2011-07 1 site
    Other conditions: Chronic Rejection of Cardiac Transplant
    View official trial listing →
  • Completed NCT NCT00598533

    Efficacy Study of Rapamycin- vs. Zotarolimus-Eluting Stents to Reduce Coronary Restenosis

    Not yet reported Deutsches Herzzentrum Muenchen 3002 participants Est. completion 2010-09 2 sites
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT00598676

    3 Limus Agent Eluting Stents With Different Polymer Coating

    Not yet reported Deutsches Herzzentrum Muenchen 2600 participants Est. completion 2009-04 2 sites
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT00598715

    Efficacy Study of Two Different Strategies for Restenosis in Sirolimus-Eluting Stents

    Not yet reported Deutsches Herzzentrum Muenchen 450 participants Est. completion 2009-08 2 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00600496

    A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)

    Not yet reported AstraZeneca 140 participants Est. completion 2025-12-18 4 sites
    Other conditions: Breast Cancer, Breast Neoplasms, Colon Cancer, Colonic Cancer, Colon Neoplasms, Lung Cancer, Melanoma, Kidney Cancer
    View official trial listing →
  • Completed NCT NCT00602693

    T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer

    Not yet reported Masonic Cancer Center, University of Minnesota 41 participants Est. completion 2015-04-16 1 site Stand-alone
    Other conditions: Leukemia, Lymphoma, Multiple Myeloma, Plasma Cell Neoplasm, Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00604357

    CNI-free de Novo Protocol in Patients Undergoing Liver Transplantation With Renal Impairment

    Not yet reported University of Regensburg 27 participants Est. completion 2012-08 1 site Stand-alone
    Other conditions: End Stage Liver Disease, Impaired Renal Function
    View official trial listing →
  • Terminated NCT NCT00606333

    Comparison of the Conor Sirolimus-eluting Coronary Stent to the Taxus Liberte Paclitaxel-eluting Coronary Stent in the Treatment of Coronary Artery Lesions

    Not yet reported Cordis US Corp. 394 participants Est. completion 2012-10 2 sites Stand-alone
    Other conditions: Coronary Atherosclerosis
    View official trial listing →
  • Completed NCT NCT00607113

    Avastin (Bevacizumab) and RAD001 (Everolimus) in Advanced Low or Intermediate Grade Neuroendocrine Carcinoma

    Not yet reported M.D. Anderson Cancer Center 41 participants Est. completion 2011-10 1 site
    Other conditions: Neuroendocrine Carcinoma
    View official trial listing →
  • Completed NCT NCT00610012

    Tumor Registry of Advanced Renal Cell Carcinoma

    iOMEDICO AG 1500 participants Est. completion 2020-05-15 1 site
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00610493

    Bevacizumab and Temsirolimus in Patients With Advanced Malignancy

    Not yet reported M.D. Anderson Cancer Center 193 participants Est. completion 2017-11-28 1 site
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT00610948

    Everolimus, Fluorouracil, Leucovorin, Panitumumab, and Oxaliplatin in Treating Patients With Tumors That Did Not Respond to Treatment

    Not yet reported UNC Lineberger Comprehensive Cancer Center 74 participants Est. completion 2016-01 1 site
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00611910

    Efficacy Study of Drug-eluting and Bare Metal Stents in Bypass Graft Lesions

    Not yet reported Deutsches Herzzentrum Muenchen 610 participants Est. completion 2011-03 4 sites Stand-alone
    Other conditions: Arteriosclerosis of Arterial Coronary Artery Bypass Graft
    View official trial listing →
  • Completed NCT NCT00612274

    Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell Transplantation

    Not yet reported Yale University 26 participants Est. completion 2014-10 1 site Stand-alone
    Other conditions: Stem Cell Transplantation
    View official trial listing →
  • Completed NCT NCT00613132

    Ph I Gleevec in Combo w RAD001 + Hydroxyurea for Pts w Recurrent MG

    Not yet reported Annick Desjardins 78 participants Est. completion 2013-01 1 site
    Obstructive sleep apnea Other conditions: Glioblastoma
    View official trial listing →
  • Completed NCT NCT00618345

    Everolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma

    Not yet reported Mayo Clinic 35 participants Est. completion 2008-08
    Other conditions: Multiple Myeloma and Plasma Cell Neoplasm
    View official trial listing →
  • Completed NCT NCT00619268

    Combination of Temsirolimus and Bevacizumab in Patient With Metastatic Renal Cell Carcinoma

    Not yet reported Centre Leon Berard 160 participants Est. completion 2012-02 29 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00619528

    HLA-Identical Sibling Renal Transplant Tolerance

    Not yet reported Northwestern University 88 participants Est. completion 2023-09 1 site Stand-alone
    Other conditions: Immunosuppression, Kidney Transplantation, Graft Rejection
    View official trial listing →
  • Completed NCT NCT00621101

    Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects

    Not yet reported University Medicine Greifswald 24 participants Est. completion 2007-06 1 site Stand-alone
    Other conditions: Pharmacokinetics, Drug Interactions, Hypercholesterolemia, Immunosuppression
    View official trial listing →
  • Completed NCT NCT00622258

    A Phase I Dose Escalation Study of RAD001 Administered in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

    Not yet reported Novartis Pharmaceuticals 13 participants Est. completion 2014-01 8 sites
    Other conditions: Non-Hodgkin's Lymphoma
    View official trial listing →
  • Completed NCT NCT00622869

    Efficacy and Safety of Concentration-controlled Everolimus to Eliminate or to Reduce Tacrolimus Compared to Tacrolimus in de Novo Liver Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 719 participants Est. completion 2012-04 91 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Terminated NCT NCT00623012

    Rapamycin for Prevention of Chronic Graft-Versus-Host Disease

    Not yet reported, Not yet reported Yale University 2 participants Est. completion 2013-08 1 site
    Other conditions: Graft Versus Host Disease
    View official trial listing →
  • Completed NCT NCT00627900

    Cost-Effectiveness Study in the Reduction of Coronary Restenosis With Sirolimus-Eluting Stents

    Not yet reported Charite University, Berlin, Germany 958 participants 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00629525

    RAD001 in Patients With Metastatic, Hormone-Refractory Prostate Cancer

    Not yet reported Daniel George, MD 35 participants Est. completion 2010-01 1 site
    Other conditions: Hormone Refractory Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00630344

    RAD001 and Bicalutamide for Androgen Independent Prostate Cancer

    Not yet reported Dana-Farber Cancer Institute 36 participants Est. completion 2012-05 2 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00631371

    Study Comparing Bevacizumab + Temsirolimus vs. Bevacizumab + Interferon-Alfa In Advanced Renal Cell Carcinoma Subjects

    Not yet reported Pfizer 791 participants Est. completion 2015-04 172 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00632268

    Low-dose RAD001(Everolimus) Plus Cisplatin-HDFL Chemotherapy for the First-line Treatment of Advanced Gastric Cancer

    Not yet reported National Taiwan University Hospital 40 participants Est. completion 2012-12 1 site
    Other conditions: Metastatic Gastric Cancer
    View official trial listing →
  • Completed NCT NCT00634244

    Comparing Three Different Combination Chemotherapy Regimens in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    Not yet reported National Cancer Institute (NCI) 92 participants Est. completion 2014-10 20 sites Stand-alone
    Other conditions: Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Erythroleukemia (M6a), Adult Pure Erythroid Leukemia (M6b), Recurrent Adult Acute Myeloid Leukemia
    View official trial listing →
  • Completed NCT NCT00634920

    Evaluation of Early Conversion to Everolimus From Cyclosporine in de Novo Renal Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 204 participants Est. completion 2013-05 8 sites
    Other conditions: Renal Function
    View official trial listing →
  • Completed NCT NCT00635284

    ABI-009 Trial in Patients With Advanced Non-hematologic Malignancies

    Not yet reported Celgene 27 participants Est. completion 2011-06-01 2 sites
    Other conditions: Solid Tumors
    View official trial listing →
  • Status unknown NCT NCT00636922

    Everolimus (RAD001) in Elderly Patients With Acute Myeloid Leukemia

    Not yet reported Bayside Health 40 participants Est. completion 2014-01 1 site
    Other conditions: Acute Myeloid Leukemia
    View official trial listing →
  • Completed NCT NCT00638794

    Assessment of Dual AntiPlatelet Therapy With Drug Eluting Stents

    Cardiovascular Research Foundation, New York 8575 participants Est. completion 2013-01 8 sites
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT00640978

    Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer

    Not yet reported M.D. Anderson Cancer Center 16 participants Est. completion 2010-03 1 site
    Other conditions: Pancreatic Cancer
    View official trial listing →
  • Terminated NCT NCT00651482

    Treatment of Refractory Metastatic Renal Cell Carcinoma With Bevacizumab and RAD001 (Everolimus)

    Not yet reported Sandy Srinivas 10 participants Est. completion 2012-03 1 site
    Other conditions: Kidney Neoplasms, Kidney (Renal Cell) Cancer
    View official trial listing →
  • No Longer Available NCT NCT00655252

    Expanded Access Study of RAD001 in Metastatic Renal Cell Cancer Patients Who Are Intolerant of or Who Have Failed Despite Prior Vascular Endothelial Growth Factor Therapy

    Novartis Pharmaceuticals 84 sites
    Other conditions: Metastatic Renal Cell Cancer
    View official trial listing →
  • Completed NCT NCT00655655

    Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors

    Not yet reported Mayo Clinic 96 participants Est. completion 2018-01-11 1 site
    Other conditions: Gastrinoma, Glucagonoma, Insulinoma, Metastatic Gastrointestinal Carcinoid Tumor, Metastatic Pheochromocytoma, Pancreatic Polypeptide Tumor, Recurrent Gastrointestinal Carcinoid Tumor, Recurrent Islet Cell Carcinoma, Recurrent Melanoma, Recurrent Neuroendocrine Carcinoma of the Skin, Recurrent Non-small Cell Lung Cancer, Recurrent Pheochromocytoma, Recurrent Renal Cell Cancer, Somatostatinoma, Stage III Neuroendocrine Carcinoma of the Skin, Stage IV Melanoma, Stage IV Non-small Cell Lung Cancer, Stage IV Renal Cell Cancer, Thyroid Gland Medullary Carcinoma, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00656643

    Dose Ranging Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Diabetic Macular Edema

    Not yet reported Santen Inc. 131 participants Est. completion 2012-05 1 site Stand-alone
    Other conditions: Diabetic Macular Edema
    View official trial listing →
  • Status unknown NCT NCT00657982

    Phase II Study of RAD001 in a Neoadjuvant Setting in Men With Intermediate or High Risk Prostate Cancer

    Not yet reported Sheba Medical Center 15 participants 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00658320

    Concentration Controlled Everolimus With Reduced Dose Cyclosporine Versus Mycophenolate Mofetil With Standard Dose Cyclosporine in de Novo Renal Transplant Adult Recipients Treated With Basiliximab and Corticosteroids

    Not yet reported Novartis 122 participants Est. completion 2012-05 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00659568

    Metformin and Temsirolimus in Treating Patients With Metastatic or Unresectable Solid Tumor or Lymphoma

    Not yet reported London Health Sciences Centre 28 participants Est. completion 2010-08 1 site
    Other conditions: Breast Cancer, Endometrial Cancer, Kidney Cancer, Lung Cancer, Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00660478

    Randomized Clinical Comparison of the Endeavor and the Cypher Coronary Stents in Non-selected Angina Pectoris Patients

    Not yet reported Evald Hoej Christiansen 2342 participants Est. completion 2009-10 1 site
    Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Completed NCT NCT00664963

    YUKON-drug-eluting Stent Below The Knee - Randomised Double-blind Study

    Not yet reported Herz-Zentrums Bad Krozingen 130 participants Est. completion 2010-04 3 sites Stand-alone
    Other conditions: Arterial Occlusive Diseases
    View official trial listing →
  • Completed NCT NCT00667485

    Rapamycin Plus Bevacizumab in Advanced Cancers

    Not yet reported University of Chicago 28 participants Est. completion 2012-05 1 site
    Other conditions: Advanced Cancer, Metastatic Cancer
    View official trial listing →
  • Completed NCT NCT00670423

    A Study Using Tacrolimus, Sirolimus and Bortezomib as Acute Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Peripheral Blood Stem Cell (PBSC) Transplantation

    Not yet reported Jennifer E. Schwartz 27 participants Est. completion 2013-10-16 1 site
    Other conditions: Graft vs Host Disease, Peripheral Blood Stem Cell Transplantation, Transplantation, Homologous
    View official trial listing →
  • Terminated NCT NCT00671112

    Everolimus and Bortezomib in Treating Patients With Relapsed or Refractory Lymphoma

    Not yet reported Brian Hill, MD, PhD 30 participants 1 site
    Other conditions: 714leukemia, Lymphoma
    View official trial listing →
  • Terminated NCT NCT00672204

    Raptiva and Sirolimus in Islet Transplantation for Type 1 Diabetes

    Not yet reported, Not yet reported University of Minnesota 23 participants Est. completion 2012-08 1 site Stand-alone
    Other conditions: Type 1 Diabetes Mellitus, Hypoglycemia
    View official trial listing →
  • Terminated NCT NCT00674414

    Trastuzumab With or Without Everolimus in Treating Women With Breast Cancer That Can Be Removed By Surgery

    Not yet reported UNICANCER 82 participants 8 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00678769

    Cixutumumab and Temsirolimus in Treating Patients With Locally Advanced or Metastatic Cancer

    Not yet reported National Cancer Institute (NCI) 72 participants Est. completion 2015-10 2 sites
    Other conditions: Malignant Neoplasm
    View official trial listing →
  • Active, not recruiting NCT NCT00679042

    Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol

    Not yet reported CellTrans Inc. 21 participants Est. completion 2026-06-14 1 site Stand-alone
    Other conditions: Type 1 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00680758

    Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer

    Not yet reported Vanderbilt-Ingram Cancer Center 18 participants Est. completion 2010-12 4 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00681213

    Tacrolimus/Sirolimus Versus Tacrolimus/Mycophenolate Mofetil (MMF) Versus Neoral/Sirolimus in Adult, Primary Kidney Transplantation

    Not yet reported University of Miami 150 participants Est. completion 2002-12 1 site Stand-alone
    Other conditions: Adult Primary Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00688753

    RAPTOR: RAD001 as Monotherapy in the Treatment of Advanced Papillary Renal Cell Tumors Program in Europe

    Not yet reported Novartis Pharmaceuticals 92 participants Est. completion 2014-10 19 sites
    Other conditions: Carcinoma, Renal Cell, Non Clear Cell Renal Carcinoma, Papillary Cell Renal Carcinoma, Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT00691015

    Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant

    Not yet reported Barbara Ann Karmanos Cancer Institute 48 participants Est. completion 2014-04 1 site
    Other conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
    View official trial listing →
  • Status unknown NCT NCT00693030

    Optical Coherence Tomography for Drug Eluting Stent Safety

    Not yet reported A.O. Ospedale Papa Giovanni XXIII 77 participants Est. completion 2008-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00693251

    Optimal Stenting Strategy For True Bifurcation Lesions

    Not yet reported Seung-Jung Park 420 participants Est. completion 2015-06 12 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00693433

    Temsirolimus and Dexamethasone in Treating Patients With Recurrent or Refractory Multiple Myeloma

    Not yet reported National Cancer Institute (NCI) 15 participants 1 site
    Other conditions: Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma
    View official trial listing →
  • Status unknown NCT NCT00693446

    A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus Corticosteroids

    Not yet reported Nantes University Hospital 118 participants Est. completion 2017-04 1 site
    Other conditions: Pancreas Transplantation, Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00694005

    Choice Of Optimal Strategy For Bifurcation Lesions With Normal Side Branch

    Not yet reported Seung-Jung Park 504 participants Est. completion 2015-01 11 sites
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT00695344

    Study to Evaluate Effect of Everolimus in Progression of Graft Vascular Illness on Patients With Heart Transplant

    Not yet reported Fundacion Investigacion y Desarrollo 52 participants Est. completion 2010-06 8 sites
    Other conditions: Cardiac Transplant
    View official trial listing →
  • Completed NCT NCT00697112

    Study Evaluating The Use Of Sirolimus In Recipients Of Kidney Allografts From Expanded Criteria Donors (ECD)

    Pfizer 53 participants Est. completion 2012-12 8 sites
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT00697372

    SEA-SIDE: Sirolimus Versus Everolimus-eluting Stent Randomized Assessment in Bifurcated Lesions and Clinical SIgnificance of Residual siDE-branch Stenosis

    Not yet reported Catholic University of the Sacred Heart 150 participants Est. completion 2010-04 1 site
    Cardiovascular disease Other conditions: Coronary Stenosis
    View official trial listing →
  • Completed NCT NCT00698607

    Efficacy of Xience/Promus Versus Cypher in rEducing Late Loss After stENTing

    Not yet reported Seoul National University Hospital 1466 participants Est. completion 2014-04 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00699491

    Cixutumumab and Temsirolimus in Treating Patients With Locally Recurrent or Metastatic Breast Cancer

    Not yet reported, Not yet reported National Cancer Institute (NCI) 48 participants Est. completion 2018-02-14 192 sites
    Other conditions: Male Breast Carcinoma, Recurrent Breast Carcinoma, Stage IV Breast Cancer AJCC v6 and v7
    View official trial listing →
  • Completed NCT NCT00700258

    Registry For Temsirolimus, Sunitinib, And Axitinib Treated Patients With Metastatic Renal Cell Carcinoma (mRCC), Mantle Cell Lymphoma (MCL), And Gastro-Intestinal Stroma Tumor (GIST) [STAR-TOR]

    Pfizer 1520 participants Est. completion 2021-12-28 77 sites
    Other conditions: Carcinoma, Renal Cell, Advanced, Lymphoma, Mantle-Cell, Gastrointestinal Stroma Tumors
    View official trial listing →
  • Completed NCT NCT00702052

    Safety and Efficacy of RAD001 in Participants With Mantle Cell Lymphoma Who Are Refractory or Intolerant to Velcade® Therapy

    Not yet reported Novartis Pharmaceuticals 58 participants Est. completion 2012-04-20 31 sites
    Other conditions: Lymphoma, Mantle- Cell
    View official trial listing →
  • Completed NCT NCT00703170

    Phase I Study of DOXIL and Temsirolimus in Resistant Solid Malignancies

    Not yet reported Washington University School of Medicine 28 participants Est. completion 2011-07 1 site
    Other conditions: Resistant Solid Malignancies
    View official trial listing →
  • Completed NCT NCT00703625

    Phase I Study of Docetaxel and Temsirolimus in Resistant Solid Malignancies

    Not yet reported Washington University School of Medicine 26 participants Est. completion 2011-06-01 1 site
    Other conditions: Resistant Solid Malignancies
    View official trial listing →
  • Completed NCT NCT00703807

    Study of the Weekly Oral RAD001 in Combination With Oral Topotecan in Patients With Advanced or Recurrent Endometrial Cancers

    Not yet reported Yale University 10 participants Est. completion 2010-05 1 site
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT00706420

    Islet Transplantation Alone (ITA) in Patients With Difficult to Control Type I Diabetes Mellitus Using a Glucocorticoid-free Immunosuppressive Regimen

    Not yet reported City of Hope Medical Center 17 participants Est. completion 2026-10-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00708591

    Study of Rapamycin Plus Ketoconazole in Advanced Cancers

    Not yet reported University of Chicago 57 participants Est. completion 2008-12 1 site
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT00708604

    Islet After Kidney Transplantation (IAK) in Patients With Type 1 Diabetes

    Not yet reported City of Hope Medical Center 3 participants Est. completion 2014-06 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00711490

    Sirolimus to Treat Diabetic Macular Edema

    Not yet reported, Not yet reported National Eye Institute (NEI) 5 participants Est. completion 2011-01 1 site Stand-alone
    Other conditions: Diabetic Retinopathy
    View official trial listing →
  • Terminated NCT NCT00712491

    Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degeneration

    Not yet reported, Not yet reported Santen Inc. 20 participants Est. completion 2010-03 1 site Stand-alone
    Other conditions: Age-related Macular Degeneration, Choroidal Neovascularization
    View official trial listing →
  • Completed NCT NCT00713284

    Study Evaluating Conversion From Tacrolimus to Sirolimus in Stable Kidney Transplant Recipients Receiving Myfortic

    Not yet reported California Pacific Medical Center Research Institute 29 participants Est. completion 2010-11 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Terminated NCT NCT00713557

    Shanghai Registry of Acute Coronary Events

    Shanghai Jiao Tong University School of Medicine 20000 participants 1 site
    Cardiovascular disease Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Completed NCT NCT00714025

    A Single Arm, Multicenter, Phase II Trial of RAD001 as Monotherapy in the Palliative Treatment of Patients With TCC After Failure of Chemotherapy

    Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 40 participants Est. completion 2012-01 1 site
    Other conditions: Transitional Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT00714623

    The SCRIPPS DES REAL WORLD Registry

    Paul S Teirstein, MD 859 participants Est. completion 2012-04 1 site
    Cardiovascular disease Other conditions: Coronary Restenosis, Coronary Thrombosis
    View official trial listing →
  • Terminated NCT NCT00714883

    Conor Cobalt Chromium Reservoir Based Stent With Sirolimus Elution in Native Coronary Artery Lesions

    Not yet reported Cordis US Corp. 3 participants Est. completion 2012-10 2 sites
    Other conditions: Coronary Disease
    View official trial listing →
  • Status unknown NCT NCT00715884

    Study Comparing the CYPHER® ELITE™ to the CYPHER® Bx VELOCITY® Sirolimus-Eluting Stent Systems

    Not yet reported Cordis US Corp. 678 participants Est. completion 2014-09 1 site Stand-alone
    Cardiovascular disease Other conditions: Coronary Atherosclerosis
    View official trial listing →
  • Completed NCT NCT00716573

    Efficacy Study of Everolimus on Renal Function in Heart Transplant Recipients With Established Chronic Renal Failure

    Not yet reported Hospices Civils de Lyon 120 participants Est. completion 2014-04-17 1 site
    Other conditions: Cardiac Transplantation, Chronic Renal Insufficiency
    View official trial listing →
  • Completed NCT NCT00723255

    Bevacizumab and Temsirolimus in Treating Patients With Recurrent or Persistent Endometrial Cancer

    Not yet reported National Cancer Institute (NCI) 53 participants Est. completion 2016-01-25 41 sites
    Other conditions: Recurrent Endometrial Carcinoma
    View official trial listing →
  • Terminated NCT NCT00727207

    Everolimus in Treating Older Patients With Mantle Cell Lymphoma Previously Treated With First-Line or Second-Line Chemotherapy

    Not yet reported Technical University of Munich 35 participants Est. completion 2014-09 1 site
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00729248

    The Differential Effects of 3 Different Immunosuppressive

    Northwestern University 12 participants Est. completion 2010-01 1 site
    Other conditions: Immunosuppression, Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00729482

    RAD001 (Everolimus) Salvage Monotherapy in Advanced Gastric Cancer (AGC) Who Failed Standard First-line Treatment

    Not yet reported Asan Medical Center 54 participants Est. completion 2013-03 1 site
    Other conditions: Stomach Neoplasm
    View official trial listing →
  • Completed NCT NCT00729586

    Temsirolimus With or Without Megestrol Acetate and Tamoxifen Citrate in Treating Patients With Advanced, Persistent, or Recurrent Endometrial Cancer

    Not yet reported National Cancer Institute (NCI) 73 participants Est. completion 2017-02 108 sites
    Other conditions: Endometrial Carcinoma, Recurrent Uterine Corpus Carcinoma, Stage IIIA Uterine Corpus Cancer, Stage IIIB Uterine Corpus Cancer, Stage IIIC1 Uterine Corpus Cancer, Stage IIIC2 Uterine Corpus Cancer, Stage IVA Uterine Corpus Cancer, Stage IVB Uterine Corpus Cancer
    View official trial listing →
  • Completed NCT NCT00729638

    RAD001 and Lenalidomide in the Treatment of Subjects With Relapsed and Relapsed/Refractory Multiple Myeloma

    Not yet reported Massachusetts General Hospital 28 participants Est. completion 2009-11 5 sites
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00736970

    Oral Deforolimus With Trastuzumab for Patients With HER2-positive Trastuzumab-Refractory Metastatic Breast Cancer (8669-009)

    Not yet reported Merck Sharp & Dohme LLC 34 participants Est. completion 2011-05
    Other conditions: Breast Cancer, Breast Neoplasms
    View official trial listing →
  • Completed NCT NCT00738556

    Spot Drug-Eluting Stenting for Long Coronary Stenoses

    Not yet reported Cardiovascular Research Society, Greece 179 participants Est. completion 2007-09 2 sites
    Other conditions: Angioplasty
    View official trial listing →
  • Completed NCT NCT00743509

    A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced Sarcoma

    Not yet reported University of Michigan Rogel Cancer Center 49 participants Est. completion 2012-09 1 site Stand-alone
    Obstructive sleep apnea
    View official trial listing →
  • Completed NCT NCT00749424

    The Study of the Crushing Technique Application Using SES in Coronary Bifurcations.

    Not yet reported Cordis US Corp. 350 participants Est. completion 2009-04 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00752362

    Per-cutaneous Intervention Based Paclitaxel and Sirolimus-Eluting Versus Bare Stents for the Treatment of de Novo Coronary Lesions (PAINT)

    Not yet reported Sahajanand Medical Technologies Limited 280 participants 11 sites Stand-alone
    Other conditions: Coronary Restenosis
    View official trial listing →
  • Completed NCT NCT00755443

    Sirolimus-Eluting Stent Versus Standard Stent in Diabetic

    Not yet reported Hospital San Carlos, Madrid 160 participants Est. completion 2005-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00756340

    A Trial of Everolimus and Bevacizumab in Children With Recurrent Solid Tumors

    Not yet reported St. Jude Children's Research Hospital 16 participants Est. completion 2015-09 1 site
    Other conditions: Recurrent or Refractory Solid Tumors, CNS Malignancies
    View official trial listing →
  • Completed NCT NCT00759850

    Drug Eluting Stent (DES) in Primary Angioplasty

    Not yet reported, Not yet reported San Giuseppe Moscati Hospital 270 participants Est. completion 2007-12 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00761644

    Doxil, Bevacizumab and Temsirolimus Trial

    Not yet reported M.D. Anderson Cancer Center 200 participants Est. completion 2019-03-28 1 site
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT00762632

    Combination of Nilotinib (AMN107) and RAD001 in Patients With Acute Myeloid Leukemia

    Not yet reported, Not yet reported Technical University of Munich 40 participants 1 site
    Other conditions: Acute Myeloid Leukemia
    View official trial listing →
  • Terminated NCT NCT00766337

    Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degeneration

    Not yet reported Santen Inc. 62 participants Est. completion 2010-03 1 site Stand-alone
    Other conditions: Age-Related Macular Degeneration, Choroidal Neovascularization
    View official trial listing →
  • Completed NCT NCT00766649

    Pilot Study of the Evaluation of Subconjunctival Sirolimus in the Treatment of Bilateral GA Associated With AMD

    Not yet reported, Not yet reported National Eye Institute (NEI) 11 participants Est. completion 2012-07 1 site Stand-alone
    Other conditions: Age-Related Macular Degeneration
    View official trial listing →
  • Completed NCT NCT00768729

    Safety of Immunosuppression Minimization in Children and Adolescents After Kidney Transplantation

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 7 participants Est. completion 2012-12 5 sites Stand-alone
    Other conditions: Kidney Failure, Chronic, Kidney Transplantation, Immunosuppression
    View official trial listing →
  • Completed NCT NCT00770120

    S0722: Everolimus in Treating Patients With Pleural Malignant Mesothelioma That Cannot Be Removed By Surgery

    Not yet reported SWOG Cancer Research Network 61 participants Est. completion 2014-04 129 sites
    Other conditions: Malignant Mesothelioma
    View official trial listing →
  • Completed NCT NCT00770263

    Erlotinib and Temsirolimus for Solid Tumors

    Not yet reported Washington University School of Medicine 46 participants Est. completion 2014-09 1 site
    Other conditions: Solid Tumors
    View official trial listing →
  • Completed NCT NCT00770731

    Study of Temsirolimus, Topotecan, and Bortezomib

    Not yet reported M.D. Anderson Cancer Center 80 participants Est. completion 2012-11 1 site
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT00775073

    Antiangiogenic Treatment of Hepatocellular Cancer With Bevacizumab and RAD001

    Not yet reported Gerhard Treiber 33 participants Est. completion 2012-04 10 sites
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT00775593

    Clofarabine and Temsirolimus in Treating Older Patients With Relapsed or Refractory Acute Myeloid Leukemia

    Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 60 participants Est. completion 2013-10-23 19 sites
    Other conditions: Leukemia
    View official trial listing →
  • Terminated NCT NCT00776373

    Rapamycin in With High-Dose Etoposide and Cytarabine in Relapsed/Refractory Aggressive Lymphoid Malignancies

    Not yet reported, Not yet reported Abramson Cancer Center at Penn Medicine 4 participants Est. completion 2009-12 1 site
    Other conditions: ALL, Burkitt's Lymphoma, Lymphoblastic Leukemia, CML
    View official trial listing →
  • Withdrawn NCT NCT00777400

    Pilot Trial to Assess Effect of CNI Conversion of Efalizumab on T Reg Cells

    Not yet reported, Not yet reported University of California, San Francisco Est. completion 2009-04 1 site Stand-alone
    Other conditions: Autoimmune Diseases
    View official trial listing →
  • Completed NCT NCT00779194

    Prospective Study of Rapamycin for the Treatment of SLE

    Not yet reported State University of New York - Upstate Medical University 99 participants Est. completion 2015-12-16 1 site
    Other conditions: Systemic Lupus Erythematosus (SLE)
    View official trial listing →
  • Completed NCT NCT00780104

    Sirolimus in Combination With MEC in High Risk Myeloid Leukemias

    Not yet reported Abramson Cancer Center at Penn Medicine 16 participants Est. completion 2010-06 1 site Stand-alone
    Other conditions: Myeloid Leukemias, AML, Leukemia, CML
    View official trial listing →
  • Status unknown NCT NCT00780429

    Pharmacokinetics and Pharmacodynamics of MPA in Stable Renal Transplant Patients

    Fondazione IRCCS Policlinico San Matteo di Pavia 54 participants 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Status unknown NCT NCT00781716

    Safety and Efficacy Study of CYPHER® Sirolimus Stent and ENDEAVOR® Zotarolimus Stent in Patients With Acute ST Elevation Myocardial Infarction (STEMI) and Analysis of Current Status of Emergency PCI Green Channel for STEMI Patients in China

    Not yet reported Beijing Chao Yang Hospital 1020 participants Est. completion 2011-05 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00781846

    Trial of Deforolimus in Combination With Bevacizumab for Patients With Advanced Cancers (8669-010)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 17 participants Est. completion 2010-02
    Other conditions: Solid Tumor
    View official trial listing →
  • Completed NCT NCT00782275

    Avastin and Temsirolimus Following Tyrosine Kinase Inhibitor Failure in Patients With Advanced Renal Cell Carcinoma

    Not yet reported Beth Israel Deaconess Medical Center 41 participants Est. completion 2015-05 3 sites
    Other conditions: Renal Cell Carcinoma, Kidney Cancer
    View official trial listing →
  • Completed NCT NCT00782626

    Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas

    Not yet reported Dana-Farber Cancer Institute 23 participants Est. completion 2012-08 10 sites
    Other conditions: Glioma, Low-grade Glioma, Astrocytoma
    View official trial listing →
  • Completed NCT NCT00784914

    A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors

    Not yet reported City of Hope Medical Center 12 participants Est. completion 2010-11 1 site Stand-alone
    Other conditions: Brain and Central Nervous System Tumors, Metastatic Cancer
    View official trial listing →
  • Completed NCT NCT00784979

    Panel Reactive Antibody (PRA) Reduction in Sensitized Patients Awaiting Renal Transplantation

    Not yet reported Tampa General Hospital 26 participants Est. completion 2012-04 1 site
    Other conditions: End Stage Renal Disease
    View official trial listing →
  • Completed NCT NCT00787969

    Rituximab, Cladribine, and Temsirolimus in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma

    Not yet reported Alliance for Clinical Trials in Oncology 74 participants Est. completion 2017-06-15 144 sites
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00788021

    Protective Immunity Project 01

    Emory University 124 participants Est. completion 2011-10 1 site
    Other conditions: Kidney Transplantation, Immunity, Immunosuppression
    View official trial listing →
  • Completed NCT NCT00788060

    A Phase Ib Study of Rad001 and Sutent to Treat Renal Cell Carcinoma

    Not yet reported Daniel George, MD 5 participants Est. completion 2012-12 1 site
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Withdrawn NCT NCT00788580

    S0718 Pazopanib and Temsirolimus in Treating Patients With Advanced Solid Tumors

    Not yet reported SWOG Cancer Research Network
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00789308

    Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 24 participants Est. completion 2014-08-21 3 sites Stand-alone
    Other conditions: Diabetes Mellitus, Type I
    View official trial listing →
  • Completed NCT NCT00789828

    Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)

    Not yet reported Novartis Pharmaceuticals 117 participants Est. completion 2014-10 24 sites
    Other conditions: Tuberous Sclerosis, Subependymal Giant Cell Astrocytoma
    View official trial listing →
  • Completed NCT NCT00790036

    Phase III Study of RAD001 Adjuvant Therapy in Poor Risk Patients With Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 Versus Matching Placebo After Patients Have Achieved Complete Response With First-line Rituximab-chemotherapy

    Not yet reported Novartis Pharmaceuticals 742 participants Est. completion 2016-06-15 202 sites
    Other conditions: Diffuse Large B-cell Lymphoma
    View official trial listing →
  • Completed NCT NCT00790400

    Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM)

    Not yet reported Novartis Pharmaceuticals 118 participants Est. completion 2015-11 25 sites
    Other conditions: Tuberous Sclerosis Complex (TSC), Lymphangioleiomyomatosis (LAM)
    View official trial listing →
  • Withdrawn NCT NCT00790439

    Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation After Kidney Transplant

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) Est. completion 2009-10 Stand-alone
    Other conditions: Diabetes Mellitus, Type I
    View official trial listing →
  • Completed NCT NCT00792766

    Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM)

    Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 20 participants Est. completion 2013-09 1 site
    Other conditions: Tuberous Sclerosis, Angiolipoma
    View official trial listing →
  • Active, not recruiting NCT NCT00792948

    Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

    Not yet reported National Cancer Institute (NCI) 97 participants Est. completion 2027-01-06 157 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Adult L1 Acute Lymphoblastic Leukemia, Adult L2 Acute Lymphoblastic Leukemia, Adult T Acute Lymphoblastic Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00793221

    Non-acute Coronary occlusIon Treated By Everolimus ELuting Stent

    Not yet reported Raul Moreno 207 participants
    Cardiovascular disease Other conditions: Coronary Occlusion, Percutaneous Coronary Intervention
    View official trial listing →
  • Completed NCT NCT00795886

    Rapamycin for Immunosuppression and B Cell Modulation Post Stem Cell Transplant for Acute Lymphoblastic Leukemia (ALL)

    Not yet reported University of Utah 63 participants Est. completion 2010-03 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00796796

    Temsirolimus and Radiation for Non-Small Cell Lung Cancer

    Not yet reported Washington University School of Medicine 10 participants Est. completion 2011-07 1 site
    Other conditions: Carcinoma, Non-Small-Cell Lung
    View official trial listing →
  • Completed NCT NCT00798954

    Treatment of Bifurcation Lesions by SINGLE STENT and KISSing Balloon Trial

    Not yet reported Vulnerable Plaque Society 800 participants Est. completion 2010-03 17 sites
    Other conditions: Ischemic Heart Disease, Restenosis
    View official trial listing →
  • Completed NCT NCT00799188

    CERTICOEUR: A Secondary Prevention Study of Skin Cancers in Heart Transplant Patients. Everolimus Versus Calcineurin Inhibitors Multicenter Trial

    Not yet reported Hospices Civils de Lyon 175 participants 1 site
    Other conditions: Cardiac Transplantation, Skin Cancer
    View official trial listing →
  • Completed NCT NCT00800722

    A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.

    Not yet reported University of California, Irvine 21 participants Est. completion 2014-06 1 site
    Other conditions: Port Wine Stain
    View official trial listing →
  • Completed NCT NCT00800917

    A Study of Temsirolimus and Bevacizumab in Recurrent Glioblastoma Multiforme

    Not yet reported Rigshospitalet, Denmark 12 participants Est. completion 2010-02 1 site
    Other conditions: Glioblastoma Multiforme
    View official trial listing →
  • Completed NCT NCT00803010

    Graft-Versus-Host Disease (GVHD) Prophylaxis After Allogeneic Peripheral Blood Hematopoietic Cell Transplantation

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 74 participants Est. completion 2012-12 1 site
    Other conditions: Acute Graft Versus Host Disease
    View official trial listing →
  • Completed NCT NCT00803816

    Everolimus for the Treatment of Uveitis Unresponsive to Cyclosporine A

    Not yet reported Carsten Heinz 12 participants Est. completion 2010-12 1 site
    Other conditions: Uveitis
    View official trial listing →
  • Completed NCT NCT00804336

    Pasireotide in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors

    Not yet reported Dana-Farber Cancer Institute 22 participants Est. completion 2015-04 3 sites
    Other conditions: Neuroendocrine Tumor, Carcinoid Tumor, Pancreatic Neuroendocrine Tumor
    View official trial listing →
  • Completed NCT NCT00805129

    Everolimus (RAD001) in Metastatic Transitional Cell Carcinoma of the Urothelium

    Not yet reported Memorial Sloan Kettering Cancer Center 46 participants Est. completion 2021-12-15 1 site
    Other conditions: Bladder Cancer, Metastatic Transitional Cell Carcinoma
    View official trial listing →
  • Terminated NCT NCT00807755

    Everolimus, Carboplatin, and Etoposide in Treating Patients With Small Cell Lung Cancer or Other Advanced Solid Tumors

    Not yet reported University of California, Davis 5 participants Est. completion 2011-12 1 site
    Other conditions: Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Terminated NCT NCT00808899

    Neuroblastoma Protocol 2008: Therapy for Children With Advanced Stage High Risk Neuroblastoma

    Not yet reported St. Jude Children's Research Hospital 4 participants Est. completion 2009-07 1 site
    Other conditions: Neuroblastoma
    View official trial listing →
  • Terminated NCT NCT00809185

    RAD001(Everolimus) in Treating Patients With Myelodysplastic Syndromes

    Not yet reported Case Comprehensive Cancer Center 7 participants Est. completion 2009-03 1 site
    Other conditions: Myelodysplastic Syndromes
    View official trial listing →
  • Terminated NCT NCT00811590

    Pilot Study of mTOR Inhibitor Therapy in Peutz-Jeghers Syndrome

    Not yet reported University of Utah 3 participants Est. completion 2011-03 1 site
    Other conditions: Peutz-Jeghers Syndrome
    View official trial listing →
  • Completed NCT NCT00811616

    A Safety and Efficacy of Supralimus™ Core™ Sirolimus Eluting Stent at MAX DDHV Institute

    Not yet reported Sahajanand Medical Technologies Limited 105 participants Est. completion 2008-03 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT00811915

    Study to Compare the Safety and Efficacy of Sirolimus (Rapamune) to Tacrolimus (Advagraf) Associated to Mycophenolate Mofetil (CellCept) Between 12 and 36 Months After Kidney Transplantation

    Not yet reported University Hospital, Rouen 65 participants Est. completion 2014-06 8 sites Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00812123

    Calcineurin Free Immunosuppression in Renal Transplant Recipients

    Not yet reported University Hospital, Basel, Switzerland 127 participants Est. completion 2005-07 1 site Stand-alone
    Chronic kidney disease Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00812786

    Pharmacokinetics of Immunosuppressive Drugs in Heart Transplant Patients

    Not yet reported University Hospital, Limoges 42 participants Est. completion 2012-05 12 sites
    Other conditions: Heart Transplant
    View official trial listing →
  • Completed NCT NCT00814788

    Bicalutamide With or Without Everolimus in Treating Patients With Recurrent or Metastatic Prostate Cancer

    Not yet reported University of California, Davis 24 participants Est. completion 2016-01 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00814944

    A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) Model

    Not yet reported Santen Inc. 143 participants Est. completion 2009-10 1 site Stand-alone
    Other conditions: Dry Eye
    View official trial listing →
  • Active, not recruiting NCT NCT00819546

    RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDS

    Not yet reported Richard Stone, MD 29 participants Est. completion 2026-12 3 sites
    Other conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
    View official trial listing →
  • Completed NCT NCT00820911

    Efficacy and Safety of AEB071 Versus Cyclosporine in de Novo Renal Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 175 participants Est. completion 2012-07 28 sites
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00821080

    Vandetanib and Sirolimus in Patients With Recurrent Glioblastoma

    Not yet reported Massachusetts General Hospital 33 participants Est. completion 2015-02 2 sites Stand-alone
    Other conditions: Glioblastoma
    View official trial listing →
  • Completed NCT NCT00823459

    Everolimus in Treating Patients With Recurrent Low-Grade Glioma

    Not yet reported Susan Chang 58 participants Est. completion 2017-11-13 1 site
    Other conditions: Adult Diffuse Astrocytoma, Adult Mixed Glioma, Adult Oligodendroglioma, Adult Subependymal Giant Cell Astrocytoma, Recurrent Adult Brain Neoplasm
    View official trial listing →
  • Status unknown NCT NCT00825773

    A Study to Evaluate Safety and Efficacy of the ExcelTM Sirolimus Eluting Stent With a Biodegradable Polymer Versus Sirolimus Eluting Stent With Non-Biodegradable Polymer in the Treatment of Patients With de Novo Coronary Artery Lesions

    Not yet reported JW Medical Systems Ltd 1944 participants Est. completion 2014-04 1 site
    Cardiovascular disease Other conditions: Ischemia, Cardiac Death
    View official trial listing →
  • Completed NCT NCT00827359

    Biomarker Trial of Everolimus in Patients With Advanced Renal Cell Carcinoma

    Not yet reported Beth Israel Deaconess Medical Center 25 participants Est. completion 2018-06 3 sites
    Other conditions: Renal Cell Carcinoma, Renal Cancer
    View official trial listing →
  • Terminated NCT NCT00827567

    Trial of RAD001 in Triple Negative Metastatic Breast Cancer

    Not yet reported Milton S. Hershey Medical Center 6 participants Est. completion 2011-02 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00827684

    Temsirolimus and Irinotecan for Treatment Resistant Patients With Metastatic Colorectal Cancer and KRAS Mutations

    Not yet reported Vejle Hospital 50 participants Est. completion 2011-06 2 sites
    Other conditions: Metastatic Colorectal Cancer
    View official trial listing →
  • Status unknown NCT NCT00828503

    Certican® (Everolimus) Against Cytomegalovirus Disease in Renal Transplant Patients

    Not yet reported Marcus Saemann 40 participants Est. completion 2014-06 1 site
    Other conditions: Cytomegalovirus Disease
    View official trial listing →
  • Terminated NCT NCT00828594

    Global Study Looking at the Combination of RAD001 and Sorafenib to Treat Patients With Advanced Hepatocellular Carcinoma

    Not yet reported Novartis Pharmaceuticals 130 participants Est. completion 2011-06 8 sites
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT00830466

    A Randomized Trial to Study Combined Pulsed Dye Laser and Rapamycin Treatment of Port Wine Stain Birthmarks.

    Not yet reported University of California, Irvine 22 participants Est. completion 2016-01 1 site
    Other conditions: Port Wine Stain
    View official trial listing →
  • Completed NCT NCT00830895

    RAD001 for Non-clear Cell Renal Cell Carcinoma (RCC)

    Not yet reported Seoul National University Hospital 49 participants Est. completion 2012-12 1 site
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Terminated NCT NCT00831480

    Everolimus (RAD001) For Advanced Renal Cell Carcinoma (RCC) Before Kidney Removal

    Not yet reported Linda C. Higgins 15 participants Est. completion 2014-12 2 sites
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT00833651

    Protective Immunity Project 02

    Emory University 97 participants Est. completion 2011-10 1 site
    Other conditions: Kidney Transplant, Immunology, Immunosuppression
    View official trial listing →
  • Withdrawn NCT NCT00834496

    Switching From One Type of Anti-rejection Drug (Tacrolimus or Cyclosporine) to Another (Sirolimus) Approximately 90-180 Days After Liver Transplantation

    Thomas Jefferson University Est. completion 2010-01 1 site
    Other conditions: Side Effects of Calcineurin Inhibitors, Renal Toxicity, Hepatic Fibrosis on Biopsy, Neurotoxicity, Post Transplant Diabetes
    View official trial listing →
  • Terminated NCT NCT00836927

    Extension Trial of Deforolimus (Ridaforolimus, MK-8669) in Participants With Advanced Cancer (MK-8669-038)

    Not yet reported Merck Sharp & Dohme LLC 7 participants Est. completion 2018-02-04
    Other conditions: Advanced Cancers
    View official trial listing →
  • Completed NCT NCT00838539

    Study Evaluating Neratinib In Combination With Temsirolimus In Subjects With Solid Tumors

    Not yet reported Puma Biotechnology, Inc. 63 participants Est. completion 2013-12 5 sites
    Other conditions: Neoplasms, Malignant Carcinoma
    View official trial listing →
  • Terminated NCT NCT00838955

    Temsirolimus for Relapsed/Refractory Hodgkin's Lymphoma

    Not yet reported Loyola University 14 participants Est. completion 2017-10 1 site
    Other conditions: Hodgkin's Lymphoma
    View official trial listing →
  • Terminated NCT NCT00843531

    RAD001 and Erlotinib in Patients With Neuroendocrine Tumors

    Not yet reported University of California, San Francisco 17 participants Est. completion 2016-08-20 1 site
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Withdrawn NCT NCT00855114

    Everolimus in Treating Women With Breast Cancer That Can Be Removed by Surgery

    Not yet reported Masonic Cancer Center, University of Minnesota Est. completion 2009-06 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT00856505

    Safety Study of Calcineurin Inhibitor Free GvHD Prophylaxis in Allogeneic Stem Cell Transplantation

    Not yet reported, Not yet reported University Hospital Freiburg 38 participants Est. completion 2011-03 1 site
    Other conditions: Hematologic Diseases
    View official trial listing →
  • Terminated NCT NCT00857259

    The Efficacy of Oral Everolimus in Patients With Neovascular Age-related Macular Degeneration

    Not yet reported Novartis Pharmaceuticals 16 participants 12 sites
    Other conditions: Choroidal Neo-Vascular Age-onset Macular Degeneration, Age-related Macular Degeneration
    View official trial listing →
  • Completed NCT NCT00858663

    Radiation Therapy (IMRT) + RAD001 (Everolimus) + Cisplatin for Patients With Head and Neck Cancer

    Not yet reported Memorial Sloan Kettering Cancer Center 13 participants Est. completion 2013-07 1 site
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Completed NCT NCT00859183

    Oral Sirolimus for In-Stent Restenosis

    Not yet reported Deutsches Herzzentrum Muenchen 300 participants Est. completion 2004-03 3 sites
    Other conditions: Coronary Restenosis
    View official trial listing →
  • Completed NCT NCT00861874

    A Study of Decitabine in Combination With Escalating Doses of Rapamycin in Patients With Relapsed or Refractory Acute Myeloid Leukemia

    Not yet reported University of Rochester 13 participants 1 site
    Other conditions: Acute Myeloid Leukemia
    View official trial listing →
  • Completed NCT NCT00862979

    A Study Investigating the Renal Tolerability, Efficacy, and Safety of a CNI-free Versus a Standard Regimen in de Novo Heart Transplant (HTx) Recipients

    Not yet reported Novartis Pharmaceuticals 162 participants Est. completion 2017-03-06 9 sites
    Other conditions: Heart Transplantation
    View official trial listing →
  • Completed NCT NCT00863655

    Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory to Letrozole or Anastrozole

    Not yet reported Novartis Pharmaceuticals 724 participants Est. completion 2014-12-04 200 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT00866684

    Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive Protocol

    Not yet reported Charite University, Berlin, Germany 44 participants Est. completion 2011-04-19 15 sites Stand-alone
    Other conditions: Skin Cancer
    View official trial listing →
  • Completed NCT NCT00866879

    Randomized Conversion of Calcineurin-Inhibitors in Renal Allograft Recipients

    Not yet reported Northwestern University 275 participants Est. completion 2019-03 1 site Stand-alone
    Other conditions: Renal Transplant Rejection
    View official trial listing →
  • Status unknown NCT NCT00868829

    Firebird2 Cobalt-Chromium Alloyed Sirolimus-Eluting Stent Registry Trial

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 5000 participants Est. completion 2013-03 1 site
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT00869999

    Everolimus Plus Rituximab for Relapsed/Refractory Diffuse Large B Cell Lymphoma

    Not yet reported Massachusetts General Hospital 26 participants Est. completion 2011-11 2 sites
    Other conditions: Diffuse Large B-cell Lymphoma
    View official trial listing →
  • Completed NCT NCT00870337

    Everolimus in Treating Patients With Relapsed or Metastatic Endometrial Cancer

    Not yet reported ARCAGY/ GINECO GROUP 44 participants 1 site
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT00874562

    Rapamycin in Relapsed Acute Lymphoblastic Leukemia

    Not yet reported Dana-Farber Cancer Institute 6 participants Est. completion 2016-04 1 site
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00876395

    Everolimus in Combination With Trastuzumab and Paclitaxel in the Treatment of HER2 Positive Locally Advanced or Metastatic Breast Cancer

    Not yet reported Novartis Pharmaceuticals 719 participants Est. completion 2017-10-23 140 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00876434

    Subconjunctival Sirolimus for the Treatment of Autoimmune Active Anterior Uveiti

    Not yet reported National Eye Institute (NEI) 5 participants Est. completion 2011-02-10 1 site
    Other conditions: Anterior Uveitis
    View official trial listing →
  • Completed NCT NCT00879333

    Safety and Efficacy of RAD001 (Everolimus) Monotherapy Plus Best Supportive Care in Patients With Advanced Gastric Cancer (AGC)

    Not yet reported Novartis Pharmaceuticals 656 participants Est. completion 2014-01 122 sites
    Other conditions: Advanced Gastric Cancer
    View official trial listing →
  • Completed NCT NCT00880282

    Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responded to Treatment

    Not yet reported National Cancer Institute (NCI) 39 participants 23 sites
    Other conditions: Unspecified Childhood Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00886691

    Bevacizumab With or Without Everolimus in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

    Not yet reported GOG Foundation 150 participants Est. completion 2015-03-23 45 sites
    Other conditions: Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma
    View official trial listing →
  • Status unknown NCT NCT00887211

    ProStent Coronary Drug-Eluting Stent

    Not yet reported CCRF Consulting Co., Ltd. 290 participants Est. completion 2010-03 1 site
    Other conditions: Coronary Disease
    View official trial listing →
  • Terminated NCT NCT00887640

    Impact of Temsirolimus Therapy on Circulating Tumor Cell Biology In Men With Castration Resistant Metastatic Prostate Cancer

    Not yet reported Duke University 11 participants Est. completion 2012-08 2 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT00890253

    Safety Study of Calcineurin-Inhibitor-Free Immunosuppression After Liver Transplantation

    Not yet reported Armin Goralczyk 29 participants Est. completion 2013-01 1 site
    Other conditions: Liver Transplantation, Chronic Renal Insufficiency
    View official trial listing →
  • Completed NCT NCT00890500

    Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.

    Not yet reported Fate Therapeutics 12 participants Est. completion 2013-10 2 sites
    Other conditions: Hematologic Malignancies, Allogeneic Stem Cell Transplantation
    View official trial listing →
  • Completed NCT NCT00891696

    Nutritional and Contractile Regulation of Muscle Growth

    Not yet reported The University of Texas Medical Branch, Galveston 144 participants Est. completion 2015-03 1 site
    Other conditions: Sarcopenia
    View official trial listing →
  • Terminated NCT NCT00892801

    Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer

    Not yet reported Vanderbilt-Ingram Cancer Center 5 participants Est. completion 2011-02 2 sites
    Other conditions: Lung Cancer, Metastatic Cancer
    View official trial listing →
  • Completed NCT NCT00895583

    Study Evaluating A Planned Transition From Tacrolimus To Sirolimus In Kidney Transplant Recipients

    Not yet reported Pfizer 254 participants Est. completion 2013-08 44 sites Stand-alone
    Other conditions: Graft Rejection, Kidney Transplant, Renal Allograft Recipients, Renal Transplant
    View official trial listing →
  • Completed NCT NCT00896012

    Kidney Biopsy Controlled Trial of Calcineurin Inhibitor Withdrawal

    Not yet reported University at Buffalo 58 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT00901849

    Tarceva/Rapamycin for Children With Low-grade Gliomas With or Without Neurofibromatosis Type 1 (NF1)

    Not yet reported Roger Packer 21 participants Est. completion 2012-10 1 site
    Other conditions: Low-grade Gliomas
    View official trial listing →
  • Completed NCT NCT00903175

    Efficacy and Safety Comparison of RAD001 Versus Sunitinib in the First-line and Second-line Treatment of Patients With Metastatic Renal Cell Carcinoma

    Not yet reported Novartis Pharmaceuticals 471 participants Est. completion 2015-05 84 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT00903188

    Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation

    Not yet reported University Hospital, Antwerp 152 participants Est. completion 2015-04 5 sites
    Other conditions: Renal Transplantation
    View official trial listing →
  • Status unknown NCT NCT00905008

    Long-Term Safety of Drug Eluting Stents in the "Real World" (FReIburger STent Registry)

    University Hospital Freiburg 1502 participants
    Other conditions: Stent Thrombosis
    View official trial listing →
  • Completed NCT NCT00908466

    Sirolimus as Therapeutic Approach to Uveitis

    Not yet reported Johns Hopkins University 30 participants Est. completion 2013-02 1 site Stand-alone
    Other conditions: Uveitis, Intermediate Uveitis, Posterior Uveitis, Panuveitis
    View official trial listing →
  • Completed NCT NCT00909831

    Hydroxychloroquine and Temsirolimus in Treating Patients With Metastatic Solid Tumors That Have Not Responded to Treatment

    Not yet reported Abramson Cancer Center at Penn Medicine 40 participants Est. completion 2013-11 1 site
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT00912340

    Phase II Trial of EVEROLIMUS ± Trastuzumab in Hormone-Refractory Metastatic Breast Cancer

    Not yet reported Emory University 70 participants Est. completion 2017-07 4 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00915603

    Trial of Paclitaxel/Bevacizumab +/- Everolimus for Patients With HER2-Negative Metastatic Breast Cancer

    Not yet reported SCRI Development Innovations, LLC 113 participants Est. completion 2014-07 15 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Terminated NCT NCT00917163

    SERIES III RUN-IN Clinical Trial: A Comparison of the Supralimus® Stent With the Xience V™ Stent

    Not yet reported Sahajanand Medical Technologies Limited 13 participants Est. completion 2010-05 28 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00918333

    Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

    Not yet reported, Not yet reported Mayo Clinic 124 participants Est. completion 2019-07-16 3 sites
    Obstructive sleep apnea Other conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, B-cell Adult Acute Lymphoblastic Leukemia, Hepatosplenic T-cell Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Primary Central Nervous System Non-Hodgkin Lymphoma, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Multiple Myeloma, Splenic Marginal Zone Lymphoma, T-cell Adult Acute Lymphoblastic Leukemia, Waldenström Macroglobulinemia
    View official trial listing →
  • Completed NCT NCT00919035

    Single Agent Temsirolimus (Torisel®) in Chemotherapy-naïve Castration-Resistant Prostate Cancer Patients

    Not yet reported Oncology Specialists, S.C. 21 participants Est. completion 2013-10 2 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00920309

    Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to Therapy

    Not yet reported, Not yet reported Yale University 21 participants Est. completion 2010-07 1 site Stand-alone
    Other conditions: Autosomal Dominant Polycystic Kidney Disease
    View official trial listing →
  • Terminated NCT NCT00921310

    Temsirolimus and Pemetrexed for Recurrent or Refractory Non-Small Cell Lung Cancer

    Not yet reported, Not yet reported Washington University School of Medicine 12 participants Est. completion 2016-04 1 site
    Other conditions: Carcinoma, Non-Small-Cell Lung
    View official trial listing →
  • Withdrawn NCT NCT00922129

    Effectiveness of Conversion to Sirolimus Versus Calcineurin Inhibitor (CNI) Reduction in Renal Transplant Patients With Prostate Cancer

    Not yet reported, Not yet reported St. Joseph's Healthcare Hamilton Est. completion 2011-01 1 site Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00923273

    Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer

    Not yet reported, Not yet reported National Cancer Institute (NCI) 42 participants Est. completion 2013-03-10 1 site Stand-alone
    Other conditions: Carcinoma, Non-Small-Cell Lung
    View official trial listing →
  • Completed NCT NCT00923845

    Low-Intensity Stem Cell Transplantation With Multiple Lymphocyte Infusions to Treat Advanced Kidney Cancer

    Not yet reported National Cancer Institute (NCI) 25 participants Est. completion 2017-06-22 1 site
    Other conditions: Renal Cell Carcinoma, Graft-Versus-Host Disease, Engraftment Syndrome
    View official trial listing →
  • Terminated NCT NCT00926107

    Study of the mTOR Inhibitor Temsirolimus (CCI-779) to Treat Ovarian Cancer With CA125 Only Relapse

    Not yet reported Hellenic Cooperative Oncology Group 9 participants Est. completion 2011-10 12 sites
    Other conditions: Ovarian Cancer
    View official trial listing →
  • Completed NCT NCT00927823

    A Trial To Assess Safety And Tolerability Of PF-04691502 In Cancer Patients

    Not yet reported Pfizer 37 participants Est. completion 2012-04 7 sites
    Other conditions: Cancer
    View official trial listing →
  • Completed NCT NCT00927966

    RAD001 in Combination With CP-751,871 in Patients Wtih Advanced Sarcomas and Other Malignant Neoplasms

    Not yet reported Suzanne George, MD 21 participants Est. completion 2011-01 1 site
    Other conditions: Sarcoma, Solid Tumor
    View official trial listing →
  • Completed NCT NCT00928018

    Tacrolimus/Sirolimus/Methotrexate vs Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma

    Not yet reported Dana-Farber Cancer Institute 139 participants Est. completion 2014-11 5 sites
    Other conditions: Non-hodgkin Lymphoma, Hodgkin Lymphoma
    View official trial listing →
  • Completed NCT NCT00928798

    Topical Rapamycin for Fibrofolliculomas

    Not yet reported Maastricht University Medical Center 19 participants Est. completion 2011-08 2 sites
    Other conditions: Birt-Hogg-Dubé Syndrome
    View official trial listing →
  • Status unknown NCT NCT00930475

    Everolimus (RAD001) and Carboplatin in Pretreated Metastatic Breast Cancer

    Not yet reported, Not yet reported Charite University, Berlin, Germany 54 participants 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00930930

    Cisplatin and Paclitaxel With or Without Everolimus in Treating Patients With Stage II or Stage III Breast Cancer

    Not yet reported Vanderbilt-Ingram Cancer Center 145 participants Est. completion 2014-10 8 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT00931255

    Tacrolimus to Sirolimus Conversion for Delayed Graft Function

    Not yet reported University of Maryland, Baltimore 32 participants Est. completion 2014-07 1 site
    Other conditions: Kidney Transplant, Delayed Graft Function
    View official trial listing →
  • Terminated NCT NCT00933374

    Trial to Evaluate Paclitaxel Plus RAD001 in Urothelial Carcinoma

    Not yet reported Heinrich-Heine University, Duesseldorf 28 participants Est. completion 2013-09 6 sites
    Other conditions: Bladder Cancer
    View official trial listing →
  • Completed NCT NCT00933777

    SORAVE - Sorafenib and Everolimus in Solid Tumors

    Not yet reported University of Cologne 36 participants Est. completion 2015-02 1 site
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific, Non-Small Cell Lung Cancer
    View official trial listing →
  • Terminated NCT NCT00934791

    Polycystic Liver Disease in Kidney Transplant

    Not yet reported Mayo Clinic 2 participants Est. completion 2012-12 1 site
    Other conditions: Polycystic Liver Disease
    View official trial listing →
  • Terminated NCT NCT00934895

    Phase I/II Study of Weekly Abraxane and RAD001 in Women With Locally Adv. or Metastatic Breast Ca

    Not yet reported, Not yet reported Rutgers, The State University of New Jersey 27 participants Est. completion 2015-08-12 3 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00935792

    Everolimus and Alemtuzumab in Treating Patients With Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

    Not yet reported, Not yet reported Mayo Clinic 28 participants Est. completion 2015-12 2 sites
    Other conditions: Lymphocytic Leukemia
    View official trial listing →
  • Completed NCT NCT00935961

    RAD001 (Everolimus) + Docetaxel + Cisplatin as Induction Chemotherapy in Patients With Local-Regional Advanced Head and Neck Cancer

    Not yet reported Memorial Sloan Kettering Cancer Center 18 participants Est. completion 2013-08 5 sites
    Other conditions: HEAD & NECK Cancer
    View official trial listing →
  • Completed NCT NCT00936702

    Carboplatin, Paclitaxel, and Everolimus in Treating Patients With Previously Untreated Cancer of Unknown Primary

    Not yet reported Alliance for Clinical Trials in Oncology 46 participants Est. completion 2013-08 141 sites
    Other conditions: Carcinoma of Unknown Primary Origin
    View official trial listing →
  • Completed NCT NCT00936858

    RAD001 for Patients With Radioiodine Refractory Thyroid Cancer

    Not yet reported Dana-Farber Cancer Institute 50 participants Est. completion 2020-02-27 4 sites
    Other conditions: Thyroid Cancer
    View official trial listing →
  • Terminated NCT NCT00938119

    Care China-Diabetes

    Johnson & Johnson Medical, China 1603 participants Est. completion 2012-12 46 sites
    Cardiovascular disease Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00940381

    Sirolimus and Cetuximab in Advanced Malignancies

    Not yet reported M.D. Anderson Cancer Center 165 participants Est. completion 2014-05 1 site Stand-alone
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT00942682

    Sorafenib in Combination With RAD001 in Patients With Advanced Neuroendocrine Tumors

    Not yet reported Dana-Farber Cancer Institute 21 participants Est. completion 2013-03 1 site
    Other conditions: Neuroendocrine Tumor, Carcinoid Tumor, Pancreatic Neuroendocrine Tumor
    View official trial listing →
  • Completed NCT NCT00942734

    Trial of RAD001 and Erlotinib With Recurrent Head and Neck Squamous Cell Carcinoma

    Not yet reported M.D. Anderson Cancer Center 49 participants Est. completion 2014-11 1 site
    Other conditions: Head And Neck Cancer
    View official trial listing →
  • Status unknown NCT NCT00942747

    Temsirolimus in Recurrent Primary Central Nervous System (CNS) Lymphoma

    Not yet reported Charite University, Berlin, Germany 37 participants Est. completion 2014-06 6 sites
    Other conditions: Recurrent or Refractory Primary CNS Lymphoma
    View official trial listing →
  • Completed NCT NCT00943956

    Everolimus, Bicalutamide, and Leuprolide Acetate in Treating Patients Undergoing Radiation Therapy For High-Risk Locally Advanced Prostate Cancer

    Not yet reported Institut du Cancer de Montpellier - Val d'Aurelle 30 participants Est. completion 2012-12 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Withdrawn NCT NCT00949026

    Assessment of Systemically Administered Torisel Delivery to Brain Tumors by Intratumoral Microdialysis

    Not yet reported Emory University Est. completion 2010-05 1 site
    Other conditions: Brain Neoplasms
    View official trial listing →
  • Completed NCT NCT00949949

    Everolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable Solid Tumors Refractory to Standard Therapy

    Not yet reported Mayo Clinic 38 participants Est. completion 2014-07 3 sites
    Other conditions: Cholangiocarcinoma of the Gallbladder, Localized Gallbladder Cancer, Unresectable Gallbladder Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Terminated NCT NCT00954512

    Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Participants With Advanced Solid Tumors (P04722, MK-7454-004)

    Not yet reported, Not yet reported Merck Sharp & Dohme LLC 15 participants Est. completion 2011-06-07
    Other conditions: Neoplasms
    View official trial listing →
  • Status unknown NCT NCT00954707

    CYPRESS - CYPHER for Evaluating Sustained Safety

    Not yet reported Cordis US Corp. 2509 participants Est. completion 2016-03 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00955773

    A Study of the GSK MEK Inhibitor GSK1120212 and Everolimus in Cancer Subjects

    Not yet reported GlaxoSmithKline 64 participants Est. completion 2011-11-08 3 sites
    Other conditions: Cancer
    View official trial listing →
  • Terminated NCT NCT00956293

    Study to Evaluate the Efficacy, Safety and Tolerability of Everolimus in de Novo Renal Transplant Recipients Participating in the Eurotransplant Senior Program

    Not yet reported Novartis Pharmaceuticals 207 participants Est. completion 2013-03 9 sites
    Other conditions: Renal Transplantation
    View official trial listing →
  • Withdrawn NCT NCT00957320

    Study of Sirolimus With PEG-Asparaginase in Acute Lymphoblastic Leukemia (ALL)

    Not yet reported Emory University Est. completion 2012-08 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00960648

    Registry to Evaluate Efficacy of Xience/Promus Versus Cypher in Reducing Late Loss After Stenting

    Seoul National University Hospital 3056 participants Est. completion 2014-01 18 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00962507

    Panobinostat and Everolimus in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

    Not yet reported City of Hope Medical Center 11 participants Est. completion 2013-01 2 sites
    Other conditions: Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
    View official trial listing →
  • Completed NCT NCT00965094

    Efficacy and Safety of Everolimus+EC-MPS After Early CNI Elimination vs EC-MPS +Tacrolimus in Renal Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 36 participants Est. completion 2013-06 3 sites
    Other conditions: Chronic Renal Failure
    View official trial listing →
  • Completed NCT NCT00967044

    Panobinostat (LBH589) Plus Everolimus (RAD001) in Patients With Relapsed and Refractory Lymphoma

    Not yet reported, Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2014-03 1 site
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00967902

    Safety and Effectiveness Study of Combo Bio-engineered Sirolimus Eluting Stent

    Not yet reported OrbusNeich 180 participants Est. completion 2015-09 1 site Stand-alone
    Other conditions: Coronary Artery Lesions
    View official trial listing →
  • Completed NCT NCT00968253

    RAD001 Study in Treatment of Relapsed or Refractory Acute Lymphocytic Leukemia

    Not yet reported, Not yet reported M.D. Anderson Cancer Center 24 participants Est. completion 2015-12 1 site
    Other conditions: Leukemia, Acute Lymphocytic Leukemia
    View official trial listing →
  • Completed NCT NCT00968591

    Pharmacokinetics of Everolimus in Subjects With Hepatic Insufficiency

    Not yet reported Novartis Pharmaceuticals 34 participants 3 sites
    Other conditions: Hepatic Insufficiency
    View official trial listing →
  • Completed NCT NCT00971789

    Sirolimus to Treat Cowden Syndrome and Other PTEN Hamartomatous Tumor Syndromes

    Not yet reported National Cancer Institute (NCI) 18 participants Est. completion 2012-10 1 site Stand-alone
    Other conditions: Cowden's Disease, Hamartoma Syndrome, Multiple
    View official trial listing →
  • Terminated NCT NCT00972335

    Trial of the Combination of Bevacizumab and Everolimus in Patients With Refractory, Progressive Intracranial Meningioma

    Not yet reported SCRI Development Innovations, LLC 18 participants Est. completion 2014-07 7 sites
    Other conditions: Intracranial Meningioma
    View official trial listing →
  • Completed NCT NCT00973076

    Study to Assess the Safety and Tolerability of the Tor Kinase Inhibitor AZD8055

    Not yet reported AstraZeneca 19 participants Est. completion 2010-12 1 site
    Other conditions: Cancer, Solid Tumors, Advanced Solid Malignancies
    View official trial listing →
  • Status unknown NCT NCT00973713

    Study of RAD001 in Advanced Cholangiocarcinoma: RADiChol

    Not yet reported Austin Health 27 participants Est. completion 2012-03 1 site
    Other conditions: Cholangiocarcinoma
    View official trial listing →
  • Terminated NCT NCT00973804

    Pilot Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Matched Unrelated Double Cord Blood Transplant for the Treatment of Leukemias, Lymphomas, and Pre-Malignant Blood Disorders

    Not yet reported National Cancer Institute (NCI) 4 participants Est. completion 2013-05-20 1 site
    Other conditions: Leukemia, Non-Hodgkins Lymphoma, Hodgkins Lymphoma, MDS, Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00975819

    Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies

    Not yet reported Denise Martin Adams 61 participants Est. completion 2020-10 2 sites Stand-alone
    Other conditions: Kaposiform Hemangioendotheliomas, Tufted Angioma, Capillary Venous Lymphatic Malformation, Venous Lymphatic Malformation, Microcystic Lymphatic Malformation, Mucocutaneous Lymphangiomatosis and Thrombocytopenia, Capillary Lymphatic Arterial Venous Malformations, PTEN Overgrowth Syndrome With Vascular Anomaly, Lymphangiectasia Syndromes
    View official trial listing →
  • Completed NCT NCT00976248

    Everolimus (RAD001) in Primary Therapy of Waldenstrom's Macroglobulinemia

    Not yet reported Dana-Farber Cancer Institute 33 participants Est. completion 2018-07 1 site
    Other conditions: Waldenstrom's Macroglobulinemia
    View official trial listing →
  • Completed NCT NCT00976573

    Carboplatin, Paclitaxel, and Bevacizumab With or Without Everolimus in Treating Patients With Metastatic Malignant Melanoma

    Not yet reported Alliance for Clinical Trials in Oncology 149 participants Est. completion 2015-09 310 sites
    Other conditions: Melanoma (Skin)
    View official trial listing →
  • Completed NCT NCT00976755

    Everolimus as First-Line Therapy in Treating Patients With Prostate Cancer

    Not yet reported Swiss Cancer Institute 37 participants Est. completion 2019-08-08 13 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT00977574

    Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

    Not yet reported National Cancer Institute (NCI) 349 participants Est. completion 2027-03-06 230 sites
    Obstructive sleep apnea Other conditions: Endometrial Adenocarcinoma, Endometrial Adenosquamous Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Recurrent Malignant Uterine Corpus Neoplasm
    View official trial listing →
  • Active, not recruiting NCT NCT00977691

    Haploidentical PBMC Transplant for Severe Congenital Anemias

    Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 23 participants Est. completion 2026-09-10 1 site Stand-alone
    Other conditions: Sickle Cell Anemia
    View official trial listing →
  • Completed NCT NCT00977938

    The Dual Antiplatelet Therapy Study (DAPT Study)

    Not yet reported Baim Institute for Clinical Research 25682 participants Est. completion 2014-06 256 sites
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT00978432

    Epigenetic Modulation in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

    Not yet reported Anne Beaven, MD 50 participants Est. completion 2016-03 1 site
    Other conditions: Diffuse Large B-cell Lymphoma
    View official trial listing →
  • Completed NCT NCT00979966

    Study in Non-Clear Cell Renal Carcinoma (Ncc-RCC) Temsirolimus Versus Sunitinib

    Not yet reported Central European Society for Anticancer Drug Research 22 participants 14 sites
    Other conditions: Non-clear Cell Renal Cell Cancer
    View official trial listing →
  • Completed NCT NCT00980460

    Risk-Based Therapy in Treating Younger Patients With Newly Diagnosed Liver Cancer

    Not yet reported National Cancer Institute (NCI) 236 participants Est. completion 2026-03-31 209 sites
    Other conditions: PRETEXT I Hepatoblastoma, PRETEXT II Hepatoblastoma, PRETEXT III Hepatoblastoma, PRETEXT IV Hepatoblastoma
    View official trial listing →
  • Completed NCT NCT00981162

    Sorafenib Tosylate and Everolimus in Treating Patients With Advanced Solid Tumors and Metastatic Pancreatic Cancer That Does Not Respond to Gemcitabine Hydrochloride

    Not yet reported Roswell Park Cancer Institute 12 participants Est. completion 2012-12 2 sites
    Other conditions: Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage IV Pancreatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Status unknown NCT NCT00982631

    A Study of Combination of Temsirolimus (Torisel®) and Pegylated Liposomal Doxorubicin (PLD, Doxil®/Caelyx®) in Advanced or Recurrent Breast, Endometrial and Ovarian Cancer

    Not yet reported Radboud University Medical Center 30 participants Est. completion 2012-08 1 site
    Other conditions: Advanced/Recurrent Breast Cancer, Endometrial Cancer, Ovarian Cancer
    View official trial listing →
  • Completed NCT NCT00985192

    Everolimus in Treating Patients With Previously Treated Unresectable or Metastatic Esophageal Cancer or Stomach Cancer

    Not yet reported Translational Oncology Research International 49 participants Est. completion 2014-05 18 sites
    Other conditions: Esophageal Cancer, Gastric Cancer
    View official trial listing →
  • Terminated NCT NCT00985374

    A Multiple Ascending Dose Study of the mTOR Inhibitor (RAD001) in Combination With R1507 in Patients With Advanced Solid Tumors

    Not yet reported Hoffmann-La Roche 11 participants Est. completion 2013-06 3 sites
    Other conditions: Neoplasms
    View official trial listing →
  • Completed NCT NCT00986050

    Comparison of Drug Eluting and Bare Metal Stents With or Without Abciximab in ST Elevation Myocardial Infarction

    Not yet reported Catharina Ziekenhuis Eindhoven 907 participants Est. completion 2009-07 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00993343

    Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantation

    Not yet reported Karolinska Institutet 215 participants Est. completion 2015-04 1 site
    Other conditions: Graft-versus-host Disease, Survival
    View official trial listing →
  • Completed NCT NCT00993499

    Trial of Continuous Once Daily Oral Treatment Using BIBW 2992 (Afatinib) Plus Sirolimus (Rapamune®) in Patients With Non-small Cell Lung Cancer Harbouring an EGFR Mutation and/or Disease Progression Following Prior Erlotinib or Gefitinib

    Not yet reported Boehringer Ingelheim 44 participants Est. completion 2014-09 8 sites Stand-alone
    Other conditions: Carcinoma, Non-Small-Cell Lung
    View official trial listing →
  • Withdrawn NCT NCT00995059

    Bortezomib Before Donor Stem Cell Transplant in Treating Patients With Multiple Myeloma

    Not yet reported, Not yet reported Mayo Clinic Stand-alone
    Other conditions: Multiple Myeloma, Refractory Multiple Myeloma
    View official trial listing →
  • Terminated NCT NCT00996346

    Phase I/II Study of Irinotecan and Temsirolimus in Patients With Refractory Sarcomas

    Not yet reported New Mexico Cancer Research Alliance 17 participants Est. completion 2013-11 1 site
    Other conditions: Sarcoma
    View official trial listing →
  • Completed NCT NCT00997711

    Evaluation of Diabetic Effects on Clinical Outcomes After Sirolimus-Eluting Stents in the AsIAN Population

    Not yet reported Seung-Jung Park 953 participants Est. completion 2012-06 14 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00997763

    Comparison of Everolimus-Eluting Stent vs Sirolimus-Eluting Stent in Patients With DIABETES Mellitus

    Not yet reported Seung-Jung Park 300 participants Est. completion 2015-08 18 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00998036

    Study of Temsirolimus, Erlotinib and Cisplatin in Solid Tumors

    Not yet reported Columbia University 9 participants Est. completion 2012-10 1 site
    Other conditions: Triple Negative Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT00999258

    Impact of Conversion From Tacrolimus to Sirolimus in African American Renal Transplant Recipients

    Not yet reported Temple University 50 participants Est. completion 2011-06 1 site
    Other conditions: Glomerular Filtration Rate, Chronic Allograft Nephropathy
    View official trial listing →
  • Completed NCT NCT00999882

    Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of Tor Kinase Inhibitor in Liver Cancer Patients

    Not yet reported AstraZeneca 26 participants Est. completion 2011-12 3 sites
    Other conditions: Cancer, Advanced Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT01005199

    Sorafenib Tosylate With or Without Everolimus in Treating Patients With Localized, Unresectable, or Metastatic Liver Cancer

    Not yet reported Swiss Cancer Institute 106 participants Est. completion 2016-03 15 sites
    Other conditions: Liver Cancer
    View official trial listing →
  • Completed NCT NCT01005706

    Sirolimus Conversions in African-American Renal Transplant Recipients

    Not yet reported Medical University of South Carolina 40 participants Est. completion 2014-07 1 site
    Other conditions: Absence; Kidney
    View official trial listing →
  • Completed NCT NCT01007942

    Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer

    Not yet reported Novartis Pharmaceuticals 569 participants Est. completion 2015-06 161 sites
    Other conditions: HER2/Neu Over-expressing Locally Advanced Breast Cancer, Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT01008917

    Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma

    Not yet reported University of California, San Francisco 25 participants Est. completion 2013-06-27 2 sites
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Terminated NCT NCT01009346

    RAD001 in Combination With Cetuximab and Cisplatin in Recurrent and Metastatic SCCHN

    Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 9 participants Est. completion 2011-03 1 site
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Terminated NCT NCT01009801

    Transarterial Chemoembolization With Doxorubicin With or Without Everolimus in Treating Patients With Liver Cancer

    Not yet reported, Not yet reported Swiss Cancer Institute 27 participants Est. completion 2015-06 8 sites
    Other conditions: Liver Cancer
    View official trial listing →
  • Terminated NCT NCT01009957

    Everolimus on CKD Progression in ADPKD Patients

    Not yet reported, Not yet reported A. Manzoni Hospital 71 participants Est. completion 2015-06 7 sites
    Other conditions: Polycystic Kidney Diseases
    View official trial listing →
  • Completed NCT NCT01010126

    Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell Cancer

    Not yet reported National Cancer Institute (NCI) 252 participants Est. completion 2017-03-13 61 sites
    Obstructive sleep apnea Other conditions: Adult Hepatocellular Carcinoma, Advanced Adult Hepatocellular Carcinoma, Endometrial Serous Adenocarcinoma, Localized Non-Resectable Adult Liver Carcinoma, Lung Carcinoid Tumor, Malignant Pancreatic Gastrinoma, Malignant Pancreatic Glucagonoma, Malignant Pancreatic Insulinoma, Malignant Pancreatic Somatostatinoma, Metastatic Digestive System Neuroendocrine Tumor G1, Ovarian Endometrioid Adenocarcinoma, Ovarian Seromucinous Carcinoma, Ovarian Serous Surface Papillary Adenocarcinoma, Pancreatic Alpha Cell Adenoma, Pancreatic Beta Cell Adenoma, Pancreatic Delta Cell Adenoma, Pancreatic G-Cell Adenoma, Pancreatic Polypeptide Tumor, Recurrent Adult Liver Carcinoma, Recurrent Digestive System Neuroendocrine Tumor G1, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Pancreatic Neuroendocrine Carcinoma, Recurrent Primary Peritoneal Carcinoma, Recurrent Uterine Corpus Carcinoma, Regional Digestive System Neuroendocrine Tumor G1, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Cancer, Stage IIIA Primary Peritoneal Cancer, Stage IIIA Uterine Corpus Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Cancer, Stage IIIB Primary Peritoneal Cancer, Stage IIIB Uterine Corpus Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Cancer, Stage IIIC Primary Peritoneal Cancer, Stage IIIC Uterine Corpus Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Cancer, Stage IV Primary Peritoneal Cancer, Stage IVA Uterine Corpus Cancer, Stage IVB Uterine Corpus Cancer
    View official trial listing →
  • Completed NCT NCT01014234

    Rapamycin and Regulatory T Cells in Kidney Transplantation

    Not yet reported Fondazione IRCCS Policlinico San Matteo di Pavia 56 participants Est. completion 2013-06 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT01014351

    Study of Everolimus With Paclitaxel and Carboplatin in Patients With Metastatic Melanoma

    Not yet reported SCRI Development Innovations, LLC 70 participants Est. completion 2013-08 12 sites
    Other conditions: Metastatic Melanoma
    View official trial listing →
  • Terminated NCT NCT01015664

    Combination of Cisplatin, Cetuximab and Temsirolimus in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

    Not yet reported, Not yet reported University of Tennessee Cancer Institute 11 participants Est. completion 2012-12 1 site
    Other conditions: Squamous Cell Carcinoma of the Head and Neck
    View official trial listing →
  • Completed NCT NCT01016015

    Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma

    Not yet reported National Cancer Institute (NCI) 178 participants Est. completion 2014-07 24 sites
    Obstructive sleep apnea Other conditions: Recurrent Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma
    View official trial listing →
  • Completed NCT NCT01016769

    Temsirolimus + Weekly Paclitaxel + Carboplatin for Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)

    Not yet reported, Not yet reported Memorial Sloan Kettering Cancer Center 48 participants Est. completion 2018-06 5 sites
    Other conditions: Squamous Cell Cancer, Head and Neck Cancer
    View official trial listing →
  • Completed NCT NCT01017029

    Everolimus in de Novo Heart Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 182 participants Est. completion 2013-12 12 sites
    Other conditions: Cardiac Transplantation
    View official trial listing →
  • Completed NCT NCT01019434

    Radiation Therapy and Temsirolimus or Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma

    Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 111 participants Est. completion 2014-03 13 sites
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Terminated NCT NCT01020305

    Temsirolimus to Reverse Androgen Insensitivity for Castration-resistant Prostate Cancer

    Not yet reported, Not yet reported Sandy Srinivas 5 participants Est. completion 2012-04 1 site
    Other conditions: Prostate Cancer, Prostatic Neoplasms, Castrate-resistant Prostate Cancer (CRPC), Androgen-insensitive Prostate Cancer, Hormone-refractory Prostate Cancer, Metastatic Disease
    View official trial listing →
  • Terminated NCT NCT01021930

    Comparison of Diabetes Mellitus and Non-diabetes Mellitus Patients for DES Surface COVERage by OCT

    Not yet reported Harbin Medical University 70 participants Est. completion 2010-12 1 site
    Other conditions: Coronary Heart Disease, Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01022996

    Study of RAD001 in Patients With Relapsed/Refractory Hodgkin Lymphoma That Has Progressed After High-dose Chemotherapy and Autologous Stem Cell Transplant and/or After Gemcitabine- or Vinorelbine- or Vinblastine-based Treatment.

    Not yet reported Novartis Pharmaceuticals 57 participants Est. completion 2014-11 16 sites
    Other conditions: Hodgkin Lymphoma
    View official trial listing →
  • Completed NCT NCT01023815

    Once-a-day Regimen With Everolimus, Low Dose Cyclosporine and Steroids in Comparison With Steroid Withdrawal or Twice a Day Regimen With Everolimus, Low Dose Cyclosporine and Steroids.

    Not yet reported Novartis 330 participants Est. completion 2012-07 28 sites
    Other conditions: de Novo Kidney Transplant Recipients, Renal Transplantation
    View official trial listing →
  • Terminated NCT NCT01023919

    Assessment of Surface Coverage of Two Types of Drug-eluting Stent in Diabetes Mellitus and Non-Diabetes Mellitus

    Not yet reported Harbin Medical University 120 participants Est. completion 2010-12 1 site
    Cardiovascular disease Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT01024179

    Relationship Between Initial Plaque Characteristics and Stent Surface Coverage Patterns

    Not yet reported Harbin Medical University 90 participants Est. completion 2010-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01024946

    Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity

    Not yet reported Memorial Sloan Kettering Cancer Center 11 participants Est. completion 2012-07 3 sites
    Other conditions: Malignant Pleural Mesothelioma
    View official trial listing →
  • Completed NCT NCT01025453

    Combination of Temsirolimus and Sorafenib in the Treatment of Radioactive Iodine Refractory Thyroid Cancer

    Not yet reported Memorial Sloan Kettering Cancer Center 37 participants Est. completion 2018-01-16 5 sites
    Other conditions: Thyroid Cancer
    View official trial listing →
  • Completed NCT NCT01025817

    Non-inferiority Study of Safety and Efficacy of Everolimus With Low Dose Tacrolimus to Mycophenolate Mofetil With Standard Dose Tacrolimus in Kidney Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 613 participants Est. completion 2013-03 50 sites
    Other conditions: Kidney Transplant
    View official trial listing →
  • Completed NCT NCT01026402

    Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Efficacy of AZD2014

    Not yet reported AstraZeneca 172 participants Est. completion 2014-08 2 sites
    Other conditions: Advanced Solid Malignancies
    View official trial listing →
  • Completed NCT NCT01026623

    Cixutumumab and Temsirolimus in Treating Patients With Metastatic Prostate Cancer

    Not yet reported, Not yet reported National Cancer Institute (NCI) 16 participants Est. completion 2013-02 4 sites
    Other conditions: Hormone-Resistant Prostate Cancer, Prostate Adenocarcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01026792

    Temsirolimus in Treating Patients With Cervical Cancer That Is Recurrent, Locally Advanced, Metastatic, or Cannot Be Removed By Surgery

    Not yet reported National Cancer Institute (NCI) 38 participants Est. completion 2012-11 1 site
    Other conditions: Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Recurrent Cervical Carcinoma, Stage IIIA Cervical Cancer, Stage IIIB Cervical Cancer, Stage IVA Cervical Cancer, Stage IVB Cervical Cancer
    View official trial listing →
  • Completed NCT NCT01027000

    Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

    Not yet reported Alliance for Clinical Trials in Oncology 68 participants Est. completion 2023-04 25 sites Stand-alone
    Other conditions: Leukemia, Lymphoma
    View official trial listing →
  • Completed NCT NCT01028092

    mTor-inhibitor (EVERolimus) Based Immunosuppressive Strategies for CNI Minimisation in OLD for Old Renal Transplantation

    Not yet reported University Hospital, Brest 327 participants Est. completion 2014-07 18 sites
    Other conditions: Renal Transplant
    View official trial listing →
  • Completed NCT NCT01031381

    Study of RAD001 and Bevacizumab in Recurrent Ovarian, Peritoneal, and Fallopian Tube Cancer

    Not yet reported University of Pittsburgh 50 participants Est. completion 2014-12 1 site
    Other conditions: Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
    View official trial listing →
  • Completed NCT NCT01031446

    Cisplatin, Paclitaxel, and Everolimus in Treating Patients With Metastatic Breast Cancer

    Not yet reported, Not yet reported Vanderbilt-Ingram Cancer Center 55 participants Est. completion 2017-08 4 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01031901

    Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

    Not yet reported The University of Texas Health Science Center, Houston 52 participants Est. completion 2011-06 1 site Stand-alone
    Other conditions: Tuberous Sclerosis, Neurofibromatoses, Angiofibroma, Neurofibroma
    View official trial listing →
  • Withdrawn NCT NCT01033500

    Calcineurin Inhibitor-free, Steroid-free Immunosuppressive Regimen in Simultaneous Islet-Kidney Transplantation for Uremic Type 1 Diabetic Patients

    Not yet reported University of Wisconsin, Madison Est. completion 2012-12 1 site Stand-alone
    Other conditions: Islets of Langerhans Transplantation, Diabetes Mellitus, Type 1, Kidney Transplantation
    View official trial listing →
  • Status unknown NCT NCT01034345

    Effect of Rapamycin on Tolerance-related Biomarkers on Stable Liver Transplant Recipients

    Not yet reported Hospital Clinic of Barcelona 52 participants Est. completion 2011-11 1 site Stand-alone
    Other conditions: Liver Transplantation
    View official trial listing →
  • Status unknown NCT NCT01034371

    Comparison of One-stop Hybrid Revascularization Versus Off-pump Coronary Artery Bypass for the Treatment of Multi-vessel Disease

    Not yet reported China National Center for Cardiovascular Diseases 400 participants 2 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01034631

    BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma

    Not yet reported, Not yet reported Hoosier Cancer Research Network 154 participants Est. completion 2016-12 108 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT01035034

    Comparison of One-stop Hybrid Revascularization Versus Percutaneous Coronary Intervention for the Treatment of Multi-vessel Disease

    Not yet reported China National Center for Cardiovascular Diseases 480 participants 2 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01035229

    Global Study Looking at the Combination of RAD001 Plus Best Supportive Care (BSC) and Placebo Plus BSC to Treat Patients With Advanced Hepatocellular Carcinoma.

    Not yet reported Novartis Pharmaceuticals 546 participants Est. completion 2013-10 131 sites
    Other conditions: Carcinoma
    View official trial listing →
  • Completed NCT NCT01035450

    Randomized Evaluation of Sirolimus-eluting Versus Everolimus-eluting Stent Trial

    Not yet reported Takeshi Morimoto 3206 participants Est. completion 2014-05 1 site
    Cardiovascular disease
    View official trial listing →
  • Withdrawn NCT NCT01038505

    Comparison of Tacrolimus and Myfortic Versus Tacrolimus and Sirolimus

    Not yet reported University of Miami Est. completion 2013-01
    Other conditions: Living Donor Kidney Transplants Patients
    View official trial listing →
  • Terminated NCT NCT01042028

    A Randomised Trial With Irinotecan, Cetuximab and Everolimus (ICE)Compared to Capecitabine and Oxaliplatin (CapOx) for Patients With Gemcitabin Resistant Pancreatic Cancer

    Not yet reported, Not yet reported Per Pfeiffer 39 participants Est. completion 2014-01 2 sites
    Other conditions: Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT01042782

    Phase I Study of Daily RAD001 in Combination With Mitomycin C in Patients With Advanced Gastric Cancer or Cancer of the Esophagogastric Junction

    Not yet reported Krankenhaus Nordwest 16 participants Est. completion 2012-08 1 site
    Other conditions: Advanced Gastric Cancer, Advanced Cancer of the Esophagogastric Junction
    View official trial listing →
  • Completed NCT NCT01046045

    Everolimus Rescue Immunosuppression in the Treatment of Chronic Allograft Dysfunction in Renal Transplant Recipients

    Not yet reported Chinese University of Hong Kong 17 participants Est. completion 2013-06 1 site
    Other conditions: Chronic Allograft Dysfunction in Renal Transplantation
    View official trial listing →
  • Completed NCT NCT01047293

    RAD001, FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma

    Not yet reported, Not yet reported University of Utah 47 participants Est. completion 2015-08 2 sites
    Other conditions: Colorectal Cancer
    View official trial listing →
  • Terminated NCT NCT01048723

    Study of RAD001 in Soft Tissue Extremity and/or Retroperitoneal Sarcomas

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 2 participants Est. completion 2011-10 1 site
    Other conditions: Sarcoma
    View official trial listing →
  • Completed NCT NCT01049620

    RAD001 in Combination With Capecitabine and Oxaliplatin (XELOX) in Patients With Advanced Gastric Cancer: RAD001+XELOX

    Not yet reported Asan Medical Center 40 participants Est. completion 2013-09 1 site
    Other conditions: Advanced Gastric Cancer
    View official trial listing →
  • No Longer Available NCT NCT01049633

    B-Lymphocyte Immunotherapy in Islet Transplantation for Initial Islet Graft Failure

    National Institute of Allergy and Infectious Diseases (NIAID) 1 site
    Other conditions: Type 1 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01049841

    Perifosine With Temsirolimus for Recurrent Pediatric Solid Tumors

    Not yet reported Memorial Sloan Kettering Cancer Center 23 participants Est. completion 2017-03 1 site
    Other conditions: Pediatric Solid Tumors
    View official trial listing →
  • Completed NCT NCT01050985

    A Study of Temsirolimus Plus Capecitabine in Patients With Advanced Cancer

    Not yet reported Georgetown University 47 participants Est. completion 2013-06 1 site
    Other conditions: Advanced Solid Tumors
    View official trial listing →
  • Completed NCT NCT01051557

    Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 36 participants Est. completion 2020-09-30 1 site
    Obstructive sleep apnea Other conditions: Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Adult Diffuse Astrocytoma, Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Mixed Glioma, Adult Oligodendroglioma, Recurrent Adult Brain Neoplasm
    View official trial listing →
  • Completed NCT NCT01051570

    Carboplatin, Everolimus, and Prednisone in Treating Patients With Metastatic Prostate Cancer That Progressed After Docetaxel

    Not yet reported Barbara Ann Karmanos Cancer Institute 26 participants Est. completion 2013-09 4 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT01051791

    Phase II Study of RAD001 Head and Neck Cancer

    Not yet reported Julie E. Bauman, MD, MPH 13 participants Est. completion 2016-08-05 1 site
    Other conditions: Squamous Cell Carcinoma of the Head and Neck
    View official trial listing →
  • Completed NCT NCT01054313

    Docetaxel and Sirolimus in Patients With Advanced Malignancies

    Not yet reported M.D. Anderson Cancer Center 103 participants Est. completion 2014-10 1 site Stand-alone
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT01055795

    Safety Study of Bevacizumab, Everolimus and LBH589 (BEL) for Advanced Solid Tumors

    Not yet reported Herbert Hurwitz 14 participants Est. completion 2012-05 1 site
    Other conditions: Advanced Solid Tumors
    View official trial listing →
  • Terminated NCT NCT01057277

    RAD001, Cisplatin and Concurrent Radiation for Locally Advanced, Inoperable Head and Neck Cancer

    Not yet reported howard safran 3 participants Est. completion 2011-06 1 site
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Terminated NCT NCT01058408

    RAD001 With Weekly Cisplatin and Radiation Therapy in Patients With Locally Advanced Head and Neck Cancer

    Not yet reported Dana-Farber Cancer Institute 3 participants 1 site
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Completed NCT NCT01058655

    RAD001 and AV-951 in Patients With Refractory, Metastatic Colorectal Cancer

    Not yet reported, Not yet reported Dana-Farber Cancer Institute 56 participants Est. completion 2015-04 3 sites
    Other conditions: Gastrointestinal Cancer
    View official trial listing →
  • Completed NCT NCT01059318

    A Study to Determine the Safety and Effectiveness of RAD001 (Everolimus) in Patients With Lymphangioleiomyomatosis

    Not yet reported Novartis Pharmaceuticals 24 participants Est. completion 2012-06 4 sites
    Other conditions: Lymphangioleiomyomatosis
    View official trial listing →
  • Completed NCT NCT01060605

    Pre Transplant Rapamycin Treatment in Islet Transplantation Alone

    Not yet reported IRCCS San Raffaele 11 participants Est. completion 2009-09 1 site
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Terminated NCT NCT01061606

    Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus

    Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2012-10 20 sites
    Obstructive sleep apnea Other conditions: Recurrent Uterine Sarcoma
    View official trial listing →
  • Completed NCT NCT01061788

    A Trial of AMG 479, Everolimus (RAD001) and Panitumumab in Patients With Advanced Cancer - QUILT-3.007

    Not yet reported Jeffrey Clarke 43 participants Est. completion 2018-12-19 1 site
    Other conditions: Advanced Solid Tumors, Non-small Cell Lung Cancer
    View official trial listing →
  • Terminated NCT NCT01061853

    Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen

    Not yet reported University Hospital, Tours 76 participants Est. completion 2012-11 9 sites Stand-alone
    Other conditions: Oral Lichen Planus
    View official trial listing →
  • Completed NCT NCT01062399

    Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

    Not yet reported, Not yet reported Radiation Therapy Oncology Group 279 participants Est. completion 2022-05-20 36 sites
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Completed NCT NCT01062555

    Calcineurin Inhibitor Sparing After Kidney Transplantation

    Not yet reported, Not yet reported University of Minnesota 527 participants Est. completion 2014-04-03 1 site
    Other conditions: CNI Side Effects
    View official trial listing →
  • Terminated NCT NCT01063478

    Dose Escalation Study of RAD001 in Combination w/Chemotherapy & Radiation in Patients With NSCLC

    Not yet reported University of Chicago 3 participants Est. completion 2012-01 1 site
    Other conditions: Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT01065662

    AZD2171 and Temsirolimus in Patients With Advanced Gynecological Malignancies

    Not yet reported Susana M. Campos, MD 11 participants Est. completion 2021-03 3 sites
    Other conditions: Endometrial Cancer, Ovarian Cancer, Cervical Cancer, Fallopian Tube Cancer, Peritoneal Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT01068249

    Letrozole and RAD001 With Advanced or Recurrent Endometrial Cancer

    Not yet reported M.D. Anderson Cancer Center 42 participants Est. completion 2028-04-30 2 sites
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT01070316

    Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)

    Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 20 participants Est. completion 2016-04 2 sites
    Other conditions: Epilepsy, Tuberous Sclerosis Complex
    View official trial listing →
  • Completed NCT NCT01072890

    Temsirolimus and Pazopanib in Patients With Advanced Solid Tumors

    Not yet reported University of California, Davis 8 participants Est. completion 2012-02 1 site
    Other conditions: Solid Tumors
    View official trial listing →
  • Withdrawn NCT NCT01073111

    Assessment of Stent Strut Coverage and Endothelial Function After Drug-Eluting Stents

    Not yet reported Hyogo Medical University Est. completion 2017-02 1 site
    Cardiovascular disease Other conditions: Atherosclerosis
    View official trial listing →
  • Completed NCT NCT01074086

    Phase I Study in RAD 001 Patients With Relapse AML

    Not yet reported French Innovative Leukemia Organisation 31 participants Est. completion 2012-12 1 site
    Other conditions: AML
    View official trial listing →
  • Completed NCT NCT01075321

    Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

    Not yet reported, Not yet reported Mayo Clinic 58 participants Est. completion 2020-02-13 2 sites
    Obstructive sleep apnea Other conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Hepatosplenic T-cell Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Peripheral T-cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Splenic Marginal Zone Lymphoma, Waldenstrom Macroglobulinemia
    View official trial listing →
  • Completed NCT NCT01076543

    Lenalidomide and Temsirolimus in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 110 participants Est. completion 2018-09-30 11 sites
    Other conditions: AIDS-Related Hodgkin Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Follicular Lymphoma, Recurrent Lymphoplasmacytic Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Non-Hodgkin Lymphoma, Recurrent T-Cell Non-Hodgkin Lymphoma, Waldenstrom Macroglobulinemia
    View official trial listing →
  • Completed NCT NCT01077986

    Everolimus, Cetuximab and Capecitabine in Patients With Metastatic Pancreatic Cancer

    Not yet reported, Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 35 participants Est. completion 2011-08 1 site
    Other conditions: Metastatic Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT01078038

    Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-III (LONG-DES-III)

    Not yet reported Seung-Jung Park 451 participants Est. completion 2010-08 20 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01078142

    Temsirolimus, Bendamustine and Rituximab for Relapsed Follicular Lymphoma or Mantle Cell Lymphoma

    Not yet reported, Not yet reported Georg Hess, MD 39 participants Est. completion 2017-09-08 1 site
    Other conditions: Follicular Lymphoma, Mantle Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT01079143

    Progression of Renal Interstitial Fibrosis / Tubular Atrophy (IF/TA) According to Epithelial-mesenchymal Transition (EMT) and Immunosuppressive Regimen (Everolimus Based Versus CNI Based) in de Novo Renal Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 194 participants Est. completion 2012-06 23 sites
    Other conditions: Renal Interstitial Fibrosis
    View official trial listing →
  • Completed NCT NCT01079286

    Study of Nelfinavir and Temsirolimus in Patients With Advanced Cancers

    Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 18 participants Est. completion 2011-08 1 site
    Other conditions: Renal Cell Cancer, Cancer
    View official trial listing →
  • Completed NCT NCT01079481

    Combination Anticancer Therapy of Paclitaxel and Everolimus for Relapsed or Refractory Small Cell Lung Cancer

    Not yet reported Samsung Medical Center 21 participants Est. completion 2013-04 1 site
    Other conditions: Small Cell Lung Cancer
    View official trial listing →
  • Status unknown NCT NCT01079702

    Everolimus and Capecitabine in Patients With Advanced Malignancy

    Not yet reported, Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 35 participants Est. completion 2011-01 2 sites
    Other conditions: Advanced Malignancies
    View official trial listing →
  • Terminated NCT NCT01079767

    Temsirolimus in Treating Patients With Advanced Liver Cancer and Cirrhosis

    Not yet reported Federation Francophone de Cancerologie Digestive 6 participants 1 site
    Other conditions: Liver Cancer
    View official trial listing →
  • Completed NCT NCT01083368

    Temsirolimus and Bevacizumab in Hormone-Resistant Metastatic Prostate Cancer That Did Not Respond to Chemotherapy

    Not yet reported, Not yet reported Case Comprehensive Cancer Center 22 participants Est. completion 2014-10 3 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT01087554

    Sirolimus or Everolimus or Temsirolimus and Vorinostat in Advanced Cancer

    Not yet reported M.D. Anderson Cancer Center 249 participants Est. completion 2026-08-18 1 site Stand-alone
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT01087983

    Lapatinib With Sirolimus or Metformin

    Not yet reported M.D. Anderson Cancer Center 111 participants Est. completion 2015-09 1 site Stand-alone
    Other conditions: Advanced Cancers
    View official trial listing →
  • Completed NCT NCT01088048

    Study to Investigate Idelalisib in Combination With Chemotherapeutic Agents, Immunomodulatory Agents and Anti-CD20 Monoclonal Antibody (mAb) in Participants With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma, Mantle Cell Lymphoma or Chronic Lymphocytic Leukemia

    Not yet reported Gilead Sciences 241 participants Est. completion 2015-04-28 11 sites
    Other conditions: Indolent Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma
    View official trial listing →
  • Status unknown NCT NCT01088893

    Everolimus in Breast Cancer Patients After Pre-operative Chemotherapy

    Not yet reported Organisation for Oncology and Translational Research 50 participants Est. completion 2013-03 1 site
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Completed NCT NCT01090466

    Gemcitabine Hydrochloride, Cisplatin, and Temsirolimus as First-Line Therapy in Treating Patients With Locally Advanced and/or Metastatic Transitional Cell Cancer of the Urothelium

    Not yet reported, Not yet reported Cardiff University 15 participants Est. completion 2016-03-16 1 site
    Other conditions: Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
    View official trial listing →
  • Terminated NCT NCT01096199

    A Study of TS-1, Cisplatin (CDDP) and RAD001 (Everolimus)

    Not yet reported National University Hospital, Singapore 35 participants 1 site
    Other conditions: Cancer
    View official trial listing →
  • Completed NCT NCT01099527

    A Trial of RAD001/Capecitabine in Refractory Gastric Cancer

    Not yet reported, Not yet reported Samsung Medical Center 59 participants Est. completion 2013-12 1 site
    Other conditions: Metastatic Gastric Cancer
    View official trial listing →
  • Terminated NCT NCT01106378

    Cynergy: the CYPHER-NEVO Registry

    Cordis US Corp. 14000 participants Est. completion 2011-12 3 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01106833

    Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801)

    Not yet reported, Not yet reported Medical College of Wisconsin 151 participants Est. completion 2018-06 31 sites Stand-alone
    Other conditions: Chronic GVHD
    View official trial listing →
  • Completed NCT NCT01107509

    Pilot Study of Neo-Adjuvant Everolimus to Treat Advanced Renal Cell Carcinoma - Analysis of Biomarkers

    Not yet reported St. Joseph's Healthcare Hamilton 20 participants Est. completion 2017-10-01 1 site
    Other conditions: Carcinoma, Renal Cell
    View official trial listing →
  • Completed NCT NCT01108445

    Phase II Study of Afinitor vs. Sutent in Patients With Metastatic Non-Clear Cell Renal Cell Carcinoma

    Not yet reported Duke University 131 participants Est. completion 2015-04 18 sites
    Other conditions: Advanced Non-clear Cell Renal Cell Carcinoma
    View official trial listing →
  • Terminated NCT NCT01111058

    Everolimus Versus Placebo in Head and Neck Cancer

    Not yet reported University of Chicago 52 participants Est. completion 2018-10 17 sites
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Terminated NCT NCT01111448

    Temsirolimus in Myelodysplastic Syndrome (MDS)

    Not yet reported Technische Universität Dresden 20 participants Est. completion 2014-06 7 sites
    Other conditions: Myelodysplastic Syndrome
    View official trial listing →
  • Completed NCT NCT01111825

    Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer

    Not yet reported, Not yet reported Puma Biotechnology, Inc. 99 participants Est. completion 2016-07 12 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01114529

    Efficacy, Safety and Evolution of Cardiovascular Parameters in Renal Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 828 participants Est. completion 2014-10-30 77 sites
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Terminated NCT NCT01115803

    A Study of LY2584702 With Erlotinib or Everolimus in Participants With Solid Tumors

    Not yet reported Eli Lilly and Company 29 participants Est. completion 2011-06 3 sites
    Other conditions: Metastases, Neoplasm, Carcinoma, Non-small Cell Lung, Renal Cell Carcinoma, Neuroendocrine Tumors
    View official trial listing →
  • Terminated NCT NCT01116232

    Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation

    Not yet reported Barbara Ann Karmanos Cancer Institute 4 participants Est. completion 2013-06 1 site Stand-alone
    Other conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
    View official trial listing →
  • Status unknown NCT NCT01118065

    Everolimus in Treating Patients With Progressive or Recurrent, Unresectable, or Metastatic Thyroid Cancer

    Not yet reported Leiden University Medical Center 42 participants 1 site
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Completed NCT NCT01120028

    Campath, Calcineurin Inhibitor Reduction and Chronic Allograft Nephropathy

    Not yet reported, Not yet reported University of Oxford 852 participants Est. completion 2020-03 20 sites Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT01120249

    S0931, Everolimus in Treating Patients With Kidney Cancer Who Have Undergone Surgery

    Not yet reported SWOG Cancer Research Network 1545 participants Est. completion 2025-09-01 1003 sites
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT01121744

    Supralimus-Core™ Pharmacokinetic (PK) Study

    Not yet reported Sahajanand Medical Technologies Limited 20 participants Est. completion 2011-01 4 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01122199

    Study of RAD001 + AMG479 for Patients With Advanced Solid Tumors

    Not yet reported Shadia Jalal 27 participants Est. completion 2015-01-19 1 site
    Other conditions: Neoplasm Metastases
    View official trial listing →
  • Completed NCT NCT01122615

    Sunitinib Plus Temsirolimus in Patients With Renal Cell Cancer (RCC)

    Not yet reported M.D. Anderson Cancer Center 23 participants Est. completion 2014-07 1 site
    Other conditions: Renal Cell Cancer, Kidney Cancer
    View official trial listing →
  • Terminated NCT NCT01125293

    Everolimus, Bortezomib and/or Rituximab in Patients With Relapsed/Refractory Waldenstrom's Macroglobulinemia

    Not yet reported, Not yet reported Dana-Farber Cancer Institute 46 participants Est. completion 2014-08 1 site
    Other conditions: Waldenstrom's Macroglobulinemia
    View official trial listing →
  • Completed NCT NCT01126333

    Long-term Follow-up of Spare the Nephron (STN) Patients

    University of Maryland, Baltimore 128 participants Est. completion 2015-06-30 1 site
    Other conditions: Kidney Transplant
    View official trial listing →
  • Completed NCT NCT01127763

    RAD001 Plus Carboplatin in Breast Cancer Patients

    Not yet reported NYU Langone Health 25 participants Est. completion 2013-03 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT01133678

    Study in Locally Advanced Squamous Cell Carcinoma of Head and Neck

    Not yet reported University of Chicago 50 participants Est. completion 2015-01 2 sites
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Status unknown NCT NCT01133925

    Optical Coherence Tomography in Long Lesions

    Not yet reported A.O. Ospedale Papa Giovanni XXIII 22 participants Est. completion 2011-05 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01134952

    Study of Sirolimus Versus Mycophenolate Liver Transplant Recipients With Recurrent Hepatitis C Virus (HCV)

    Not yet reported London Health Sciences Centre 11 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Hepatitis C
    View official trial listing →
  • Completed NCT NCT01135563

    Study of Vinblastine and Sirolimus in Children With Recurrent/Refractory Solid Tumours Including CNS Tumours

    Not yet reported The Hospital for Sick Children 14 participants Est. completion 2012-04 5 sites Stand-alone
    Other conditions: Solid Tumors, Central Nervous System Tumors
    View official trial listing →
  • Completed NCT NCT01136733

    A Study of E7080 Alone, and in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Renal Cell Carcinoma Following One Prior Vascular Endothelial Growth Factor (VEGF)-Targeted Treatment

    Not yet reported, Not yet reported Eisai Inc. 173 participants Est. completion 2018-02-08 37 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01139138

    Safety Study of the Combination of Panitumumab, Irinotecan and Everolimus in the Treatment of Advanced Colorectal Cancer

    Not yet reported, Not yet reported The Queen Elizabeth Hospital 49 participants Est. completion 2017-06 1 site
    Other conditions: Colorectal Cancer, Colorectal Carcinoma, Colorectal Tumors, Neoplasms, Colorectal
    View official trial listing →
  • Completed NCT NCT01141244

    Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid Tumors

    Not yet reported National Cancer Institute (NCI) 72 participants 25 sites
    Other conditions: Unspecified Childhood Solid Tumor, Protocol Specific
    View official trial listing →
  • Active, not recruiting NCT NCT01141309

    Evaluating the Combination of Everolimus and Sorafenib in the Treatment of Thyroid Cancer

    Not yet reported Memorial Sloan Kettering Cancer Center 41 participants Est. completion 2027-06 4 sites
    Other conditions: Thyroid Cancer
    View official trial listing →
  • Completed NCT NCT01143779

    FLT-PET as an Imaging Biomarker With Temsirolimus, Topotecan, and Bortezomib

    Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2021-12-27 1 site
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT01145079

    A New Strategy Regarding Discontinuation of Dual Antiplatelet

    Not yet reported Yonsei University 982 participants Est. completion 2012-01 1 site
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT01148628

    Dose-finding Study of CAELYXTM and RAD001 in Patients With Advanced Solid Tumors

    Not yet reported Southern Europe New Drug Organization 54 participants Est. completion 2011-12 3 sites
    Other conditions: Advanced Solid Tumors
    View official trial listing →
  • Terminated NCT NCT01149434

    Study of JI-101 in Patients With Advanced Low Grade Endocrine Tumors, Ovarian Cancers or K-RAS Mutant Colon Cancers

    Not yet reported, Not yet reported University of Utah 19 participants Est. completion 2012-08 1 site
    Other conditions: Cancer, Neuroendocrine, Ovarian Cancer, Colon Cancer
    View official trial listing →
  • Completed NCT NCT01150097

    Extension Study to Evaluate the Long-term Efficacy and Safety of Everolimus in Liver Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 284 participants Est. completion 2013-05-03 57 sites
    Other conditions: Liver Transplant Recipient
    View official trial listing →
  • Completed NCT NCT01152801

    Safety of RAD001 in Chinese Patients With Metastatic Renal Cell Cancer

    Not yet reported Novartis Pharmaceuticals 64 participants Est. completion 2013-12 7 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01152827

    RAD001 in Pheochromocytoma or Nonfunctioning Carcinoid

    Not yet reported Seoul National University Hospital 33 participants Est. completion 2011-12 1 site
    Other conditions: Pheochromocytoma, Extra-adrenal Paraganglioma, Non-functioning Carcinoid
    View official trial listing →
  • Completed NCT NCT01152840

    Study of RAD001 in Adenoid Cystic Carcinoma

    Not yet reported Seoul National University Hospital 33 participants Est. completion 2012-12 1 site
    Other conditions: Adenoid Cystic Carcinoma
    View official trial listing →
  • Completed NCT NCT01154335

    Everolimus and OSI-906 for Patients With Refractory Metastatic Colorectal Cancer

    Not yet reported SCRI Development Innovations, LLC 18 participants Est. completion 2013-05 2 sites
    Other conditions: Metastatic Colorectal Cancer
    View official trial listing →
  • Completed NCT NCT01154439

    Everolimus MICE-regimen in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia

    Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 11 participants Est. completion 2015-09-15 5 sites
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT01155258

    Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors

    Not yet reported University of Southern California 19 participants Est. completion 2014-05 1 site
    Other conditions: Extensive Stage Small Cell Lung Cancer, Hereditary Paraganglioma, Male Breast Cancer, Malignant Paraganglioma, Metastatic Gastrointestinal Carcinoid Tumor, Metastatic Pheochromocytoma, Pancreatic Polypeptide Tumor, Recurrent Breast Cancer, Recurrent Cervical Cancer, Recurrent Endometrial Carcinoma, Recurrent Gastrointestinal Carcinoid Tumor, Recurrent Islet Cell Carcinoma, Recurrent Neuroendocrine Carcinoma of the Skin, Recurrent Non-small Cell Lung Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Pheochromocytoma, Recurrent Prostate Cancer, Recurrent Renal Cell Cancer, Recurrent Small Cell Lung Cancer, Recurrent Uterine Sarcoma, Regional Gastrointestinal Carcinoid Tumor, Regional Pheochromocytoma, Stage III Cervical Cancer, Stage III Endometrial Carcinoma, Stage III Neuroendocrine Carcinoma of the Skin, Stage III Ovarian Epithelial Cancer, Stage III Ovarian Germ Cell Tumor, Stage III Prostate Cancer, Stage III Renal Cell Cancer, Stage III Uterine Sarcoma, Stage IIIA Breast Cancer, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Breast Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer, Stage IV Endometrial Carcinoma, Stage IV Neuroendocrine Carcinoma of the Skin, Stage IV Non-small Cell Lung Cancer, Stage IV Ovarian Epithelial Cancer, Stage IV Ovarian Germ Cell Tumor, Stage IV Prostate Cancer, Stage IV Renal Cell Cancer, Stage IV Uterine Sarcoma, Stage IVA Cervical Cancer, Stage IVB Cervical Cancer, Thyroid Gland Medullary Carcinoma
    View official trial listing →
  • Completed NCT NCT01157858

    Everolimus and LongActing Octreotide Trial in Polycystic Livers

    Not yet reported Radboud University Medical Center 44 participants Est. completion 2012-07 1 site
    Other conditions: Polycystic Liver Disease
    View official trial listing →
  • Completed NCT NCT01158651

    Everolimus for Children With NF1 Chemotherapy-Refractory Radiographic Progressive Low Grade Gliomas

    Not yet reported University of Alabama at Birmingham 23 participants Est. completion 2017-10-26 12 sites
    Other conditions: Glioma
    View official trial listing →
  • Completed NCT NCT01162551

    Trial of Sirolimus and Methotrexate in Relapsed/Refractory Lymphoblastic Leukemia and Lymphoma

    Not yet reported Children's Hospital of Philadelphia 5 participants Est. completion 2017-02 1 site Stand-alone
    Other conditions: Cancer, Leukemia, Lymphoma
    View official trial listing →
  • Completed NCT NCT01163357

    Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma

    Not yet reported City of Hope Medical Center 18 participants Est. completion 2024-05-20 1 site Stand-alone
    Other conditions: Autologous Hematopoietic Stem Cell Transplant Recipient, Loss of Chromosome 17p, Plasma Cell Leukemia, Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
    View official trial listing →
  • Withdrawn NCT NCT01163929

    A Study to Look at the Combination of Chemotherapy, Trastuzumab and RAD001 in HER2 Positive Breast Cancer

    Not yet reported University of Kansas Est. completion 2012-03
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01164176

    Everolimus in Treating Patients With Locally Advanced or Metastatic Thyroid Cancer

    Not yet reported Yonsei University 40 participants Est. completion 2014-10 7 sites
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Completed NCT NCT01164267

    Multicenter Phase II Study to Evaluate the Clinical Activity and the Safety Profile of Everolimus in Marginal Zone B-cell Lymphomas (MZL)

    Not yet reported International Extranodal Lymphoma Study Group (IELSG) 30 participants 10 sites
    Other conditions: Marginal Zone B-cell Lymphoma
    View official trial listing →
  • Terminated NCT NCT01166126

    Temsirolimus/AZD 6244 for Treatment-naive With BRAF Mutant Unresectable Stage IV

    Not yet reported National Cancer Institute (NCI) 4 participants Est. completion 2012-06 1 site
    Obstructive sleep apnea Other conditions: Recurrent Melanoma, Stage IV Melanoma
    View official trial listing →
  • Terminated NCT NCT01166724

    Renal Allograft Function and Histology Following Switching From A Tacrolimus to Sirolimus (SRL)-Based Immunosuppression-

    Not yet reported The Cleveland Clinic 12 participants Est. completion 2014-12 1 site
    Other conditions: Kidney Transplant
    View official trial listing →
  • Completed NCT NCT01167530

    Study to Evaluate RAD001 in Combination With Radiotherapy in Non-small Cell Lung Cancer

    Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 26 participants Est. completion 2017-02-09 1 site
    Other conditions: Non-small Cell Lung Cancer, Locally Advanced Disease
    View official trial listing →
  • Completed NCT NCT01169701

    24 Months Follow-up, Two Arm Study to Compare the Cardiovascular Profile in a Regimen With Everolimus + Mycophenolic Acid (MPA) Versus (vs.) a Regimen of CNI+MPA in Maintenance Renal Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 71 participants Est. completion 2014-03 9 sites
    Other conditions: Renal Transplant
    View official trial listing →
  • Withdrawn NCT NCT01170052

    Bendamustine and Temsirolimus in Patients With Relapsed or Refractory Mantle Cell Non-Hodgkin's Lymphoma (NHL)

    Not yet reported, Not yet reported Charite University, Berlin, Germany 20 participants Est. completion 2014-04 3 sites
    Other conditions: Mantle Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT01172769

    Efficacy Study of Temsirolimus to Treat Head and Neck Cancer

    Not yet reported Hannover Medical School 42 participants Est. completion 2012-03 7 sites
    Other conditions: Head and Neck Squamous Cell Carcinoma
    View official trial listing →
  • Terminated NCT NCT01174199

    Temsirolimus and Vorinostat in Treating Patients With Metastatic Prostate Cancer

    Not yet reported Roswell Park Cancer Institute 13 participants Est. completion 2016-08 2 sites
    Other conditions: Prostate Cancer, Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer, Recurrent Prostate Cancer, Stage IV Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT01175096

    Safety and Tolerability Profile of RAD001 Daily in Chinese Patients With Advanced Pulmonary Neuroendocrine Tumor

    Not yet reported, Not yet reported Guangdong Provincial People's Hospital 20 participants Est. completion 2012-01 1 site
    Other conditions: Neuroendocrine Tumors, Carcinoid Tumor
    View official trial listing →
  • Completed NCT NCT01177397

    Study to Assess Safety, Pharmacokinetics, and Efficacy of Oral CC-223 for Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma or Multiple Myeloma

    Not yet reported, Not yet reported Celgene 226 participants Est. completion 2016-12-09 16 sites
    Other conditions: Multiple Myeloma, Diffuse Large B-Cell Lymphoma, Glioblastoma Multiforme, Hepatocellular Carcinoma, Non-Small Cell Lung Cancer, Neuroendocrine Tumors of Non-Pancreatic Origin, Hormone Receptor-Positive Breast Cancer
    View official trial listing →
  • Withdrawn NCT NCT01178151

    Study of Everolimus in the Treatment of Advanced Malignancies in Patients With Peutz-Jeghers Syndrome

    Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Est. completion 2015-04 2 sites
    Other conditions: Peutz-Jeghers Syndrome, Neoplastic Processes, Neoplasm Metastasis
    View official trial listing →
  • Completed NCT NCT01180049

    Comparison Of 2 Doses Of Temsirolimus (Torisel) In Patients With Mantle Cell Lymphoma

    Not yet reported Pfizer 101 participants Est. completion 2018-06 31 sites
    Other conditions: Non-Hodgkin's Lymphoma
    View official trial listing →
  • Completed NCT NCT01181271

    Tandem Auto-Allo Transplant for Lymphoma

    Not yet reported Massachusetts General Hospital 42 participants Est. completion 2016-02 2 sites Stand-alone
    Other conditions: Diffuse, Large B-Cell, Lymphoma, Lymphoma, Low-Grade, T-Cell Lymphoma, Mantle-Cell Lymphoma, Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Lymphoma, Small Lymphocytic
    View official trial listing →
  • Completed NCT NCT01182168

    Gemcitabine and Split-Dose Cisplatin Plus Everolimus (RAD001) in Patients With Advanced Solid Tumor Malignancies

    Not yet reported Memorial Sloan Kettering Cancer Center 12 participants Est. completion 2016-03 1 site
    Other conditions: Bladder Cancer, Renal Pelvis Cancer, Ureter Cancer
    View official trial listing →
  • Completed NCT NCT01182649

    Everolimus Stent in Patients With Coronary Artery Disease (CAD)

    Not yet reported San Giuseppe Moscati Hospital 600 participants Est. completion 2010-06 1 site
    Cardiovascular disease Other conditions: Coronary Atherosclerosis
    View official trial listing →
  • Withdrawn NCT NCT01182883

    A Phase I Study of IMC-A12 in Combination With Temsirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors

    Not yet reported National Cancer Institute (NCI) Est. completion 2012-04-04
    Other conditions: Brain Stem Neoplasms, Glioma, Pinealoma
    View official trial listing →
  • Completed NCT NCT01183247

    An Open, Single Centre, Randomised, Parallel Group Study to Investigate Three Different Immunosuppressive Regimens

    Not yet reported University Hospital, Basel, Switzerland 63 participants Est. completion 2010-06 1 site
    Other conditions: Comparative Study, Immunosuppressive Agents
    View official trial listing →
  • Completed NCT NCT01183663

    Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)

    Not yet reported M.D. Anderson Cancer Center 180 participants Est. completion 2016-05 1 site
    Other conditions: Advanced Cancers
    View official trial listing →
  • Completed NCT NCT01184326

    Expanded Phase I Pazopanib and Everolimus in Advanced Solid Tumors and Previously Treated Advanced Urothelial Cancer

    Not yet reported Dana-Farber Cancer Institute 23 participants Est. completion 2017-03 2 sites
    Other conditions: Solid Tumor, Kidney Cancer
    View official trial listing →
  • Completed NCT NCT01184885

    A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 7 participants Est. completion 2013-04 2 sites Stand-alone
    Other conditions: Lymphoid Malignancies (New or Relapsed), Acute Lymphoblastic Leukemia, Burkitt Lymphoma, Lymphoblastic Lymphoma, Mantle Cell Lymphoma, Adult T-cell Leukemia/Lymphoma
    View official trial listing →
  • Completed NCT NCT01184898

    Pilot Trial of Sirolimus/MEC in High Risk Acute Myelogenous Leukemia (AML)

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 36 participants Est. completion 2016-02 2 sites Stand-alone
    Other conditions: AML
    View official trial listing →
  • Terminated NCT NCT01185366

    Everolimus Versus Sunitinib in Non-Clear Cell Renal Cell Carcinoma

    Not yet reported M.D. Anderson Cancer Center 73 participants Est. completion 2019-09-09 4 sites
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT01186094

    Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-IV: (LONG-DES-IV)

    Not yet reported Seung-Jung Park 502 participants Est. completion 2011-06 12 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01186107

    Comparison of Zotarolimus-Eluting Stent vs Sirolimus-Eluting Stent for Diabetic Patients

    Not yet reported Seung-Jung Park 256 participants Est. completion 2013-07 11 sites
    Cardiovascular disease Other conditions: Diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT01187199

    Phase I Trial of Bevacizumab and Temsirolimus in Combination With 1) Carboplatin, 2) Paclitaxel, 3) Sorafenib for the Treatment of Advanced Cancer

    Not yet reported M.D. Anderson Cancer Center 278 participants Est. completion 2026-04-30 1 site
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT01188798

    Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies

    Not yet reported St. Jude Children's Research Hospital 6 participants Est. completion 2012-02 1 site
    Other conditions: Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia, Chronic Myelocytic Leukemia, Hodgkin's Disease, Myelodysplastic Syndrome
    View official trial listing →
  • Withdrawn NCT NCT01188889

    RAD001 in Patients With Chronic Phase Chronic Myeloid Leukemia w/ Molecular Disease.

    Not yet reported, Not yet reported University of Michigan Rogel Cancer Center Est. completion 2017-12 1 site
    Other conditions: Chronic Myeloid Leukemia
    View official trial listing →
  • Terminated NCT NCT01190241

    Targeted Therapy Selection Based on Tumor Tissue Kinase Activity Profiles for Patients With Advanced Solid Malignancies, an Exploratory Study

    Not yet reported Amsterdam UMC, location VUmc 45 participants Est. completion 2017-12 2 sites
    Other conditions: Advanced Solid Tumors, Inoperable, Metastasis
    View official trial listing →
  • Withdrawn NCT NCT01194193

    Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours

    Not yet reported AstraZeneca 63 participants
    Other conditions: Cancer, Advanced Solid Tumours, Lymphomas
    View official trial listing →
  • Completed NCT NCT01195194

    Selection of Immunosuppression in Kidney Transplant Recipients Depending on Pre-transplant Donor-specific T-cell Reactivity.

    Not yet reported Josep M Grinyo 61 participants Est. completion 2013-06 2 sites Stand-alone
    Other conditions: Disorder Related to Renal Transplantation
    View official trial listing →
  • Completed NCT NCT01195922

    Rapamycin Therapy in Head and Neck Squamous Cell Carcinoma

    Not yet reported, Not yet reported National Institute of Dental and Craniofacial Research (NIDCR) 37 participants Est. completion 2015-12 1 site Stand-alone
    Other conditions: Mouth Neoplasms, Head and Neck Neoplasms, Tongue Neoplasms, Carcinoma, Squamous Cell
    View official trial listing →
  • Completed NCT NCT01196429

    Temsirolimus, Carboplatin, and Paclitaxel as First-Line Therapy in Treating Patients With Newly Diagnosed Stage III-IV Clear Cell Ovarian Cancer

    Not yet reported National Cancer Institute (NCI) 90 participants Est. completion 2015-01 145 sites
    Other conditions: Ovarian Clear Cell Cystadenocarcinoma, Stage III Ovarian Cancer, Stage IV Ovarian Cancer
    View official trial listing →
  • Completed NCT NCT01196819

    Randomized MicroPort's Firehawk DES Versus Xience V: TARGET I Trial

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 458 participants Est. completion 2016-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01197170

    Hormone Receptor Positive Disease Across Solid Tumor Types: A Phase I Study of Single-Agent Hormone Blockade and Combination Approaches With Targeted Agents to Provide Synergy and Overcome Resistance

    Not yet reported M.D. Anderson Cancer Center 277 participants Est. completion 2021-01-13 1 site
    Other conditions: Solid Tumors, Advanced Cancer
    View official trial listing →
  • Terminated NCT NCT01198158

    Everolimus With or Without Bevacizumab in Treating Patients With Advanced Kidney Cancer That Progressed After First-Line Therapy

    Not yet reported National Cancer Institute (NCI) 77 participants Est. completion 2017-12-16 524 sites
    Other conditions: Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v7, Stage IV Renal Cell Cancer AJCC v7
    View official trial listing →
  • Completed NCT NCT01198184

    Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 and Temsirolimus in Treating Patients With Advanced Solid Tumors

    Not yet reported National Cancer Institute (NCI) 18 participants Est. completion 2013-10 2 sites
    Other conditions: Endometrial Papillary Serous Carcinoma, Recurrent Endometrial Carcinoma, Recurrent Renal Cell Cancer, Stage III Endometrial Carcinoma, Stage III Renal Cell Cancer, Stage IV Endometrial Carcinoma, Stage IV Renal Cell Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT01198665

    RAD001 Combined With CHOP in Newly Diagnosed Peripheral T-cell Lymphomas

    Not yet reported, Not yet reported Samsung Medical Center 46 participants Est. completion 2014-12 5 sites
    Other conditions: Peripheral T Cell Lymphoma Unspecified, Anaplastic Large Cell Lymphoma, ALK-negative, Angioimmunoblastic T Cell Lymphoma, Cutaneous T Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT01200693

    Z-SEA-SIDE: Sirolimus Versus Everolimus Versus Zotarolimus-eluting Stent Assessment in Bifurcated Lesions and Clinical SIgnificance of Residual siDE-branch Stenosis

    Not yet reported Catholic University of the Sacred Heart 80 participants Est. completion 2012-03 1 site
    Cardiovascular disease Other conditions: Coronary Stenosis
    View official trial listing →
  • Completed NCT NCT01201369

    A Study to Examine the Implantation Characteristics of Two Drug-Eluting Stents

    Not yet reported Royal Brompton & Harefield NHS Foundation Trust 40 participants Est. completion 2011-07 1 site
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT01202058

    An Observational Safety Evaluation of Patients Treated With the NEVO™ Sirolimus-eluting Coronary Stent. (NEVO II)

    Not yet reported Cordis US Corp. 156 participants Est. completion 2012-10 3 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01203722

    Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies

    Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 87 participants Est. completion 2024-05-28 1 site
    Other conditions: Hematologic Malignancies
    View official trial listing →
  • Terminated NCT NCT01204450

    Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft Tissue Sarcoma

    Not yet reported UNC Lineberger Comprehensive Cancer Center 7 participants Est. completion 2013-03 2 sites
    Other conditions: Brain and Central Nervous System Tumors, Neuroblastoma, Sarcoma, Unspecified Childhood Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT01204476

    Cixutumumab, Everolimus, and Octreotide Acetate in Treating Patients With Advanced Low to Intermediate Grade Neuroendocrine Carcinoma

    Not yet reported National Cancer Institute (NCI) 27 participants 1 site
    Other conditions: Gastrin-Producing Neuroendocrine Tumor, Lung Carcinoid Tumor, Metastatic Digestive System Neuroendocrine Tumor G1, Pancreatic Glucagonoma, Pancreatic Insulinoma, Pancreatic Polypeptide Tumor, Paraganglioma, Recurrent Digestive System Neuroendocrine Tumor G1, Recurrent Merkel Cell Carcinoma, Recurrent Pancreatic Neuroendocrine Carcinoma, Regional Digestive System Neuroendocrine Tumor G1, Somatostatin-Producing Neuroendocrine Tumor, Stage III Merkel Cell Carcinoma, Stage IV Merkel Cell Carcinoma, Thyroid Gland Medullary Carcinoma
    View official trial listing →
  • Completed NCT NCT01206036

    CESAR Study in Prostate Cancer With Temsirolimus Added to Standard Docetaxel Therapy (CEPTAS)

    Not yet reported, Not yet reported Central European Society for Anticancer Drug Research 19 participants Est. completion 2015-10 2 sites
    Other conditions: Prostatic Neoplasms
    View official trial listing →
  • Completed NCT NCT01206140

    Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery

    Not yet reported National Cancer Institute (NCI) 70 participants Est. completion 2015-04 8 sites
    Other conditions: Recurrent Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma
    View official trial listing →
  • Completed NCT NCT01206764

    A Trial of Everolimis in Patients With Advanced Renal Cell Carcinoma.

    Not yet reported Novartis Pharmaceuticals 143 participants Est. completion 2017-07-01 22 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01210482

    Temsirolimus (Torisel) Drug Use Investigation (Regulatory Post Marketing Commitment Plan)

    Pfizer 1050 participants Est. completion 2018-05-31 1 site
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Terminated NCT NCT01213394

    Mycophenolate Mofetil for Reducing Cardiovascular Risk in Renal Transplant Recipients

    Not yet reported Ramesh Prasad 2 participants Est. completion 2011-12 1 site Stand-alone
    Cardiovascular disease Other conditions: Kidney Transplantation
    View official trial listing →
  • Terminated NCT NCT01215136

    First-line Everolimus +/- Paclitaxel for Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma

    Not yet reported Matthew Galsky 36 participants Est. completion 2018-04-24 11 sites
    Other conditions: Transitional Cell Carcinoma, Bladder Carcinoma, Urothelial Carcinoma
    View official trial listing →
  • Status unknown NCT NCT01216826

    Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Osteosarcoma

    Not yet reported Sidnei Epelman 20 participants Est. completion 2014-12 1 site
    Obstructive sleep apnea
    View official trial listing →
  • Status unknown NCT NCT01216839

    Phase II Study of Everolimus in Children and Adolescents With Refractory or Relapsed Rhabdomyosarcoma and Other Soft Tissue Sarcomas

    Not yet reported Sidnei Epelman 20 participants Est. completion 2013-12 1 site
    Other conditions: Refractory or Relapsed RMS and Soft Tissue Sarcomas
    View official trial listing →
  • Completed NCT NCT01217125

    Rapamycin In Angiomyolipomas In Patients With Tuberous Sclerosis

    Not yet reported Fundacio Puigvert 18 participants Est. completion 2011-05
    Other conditions: Angiomyolipoma
    View official trial listing →
  • Completed NCT NCT01217177

    A Study of mTOR Inhibitor Everolimus (RAD001) in Association With Cisplatin and Radiotherapy for Locally Advanced Cervix Cancer

    Not yet reported Novartis Pharmaceuticals 14 participants Est. completion 2014-04 2 sites
    Other conditions: Locally Advanced Cervical Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT01217931

    Sequential Two-agent Assessment in Renal Cell Carcinoma Therapy: The START Trial

    Not yet reported M.D. Anderson Cancer Center 180 participants Est. completion 2028-01-31 1 site
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT01218555

    Study of Everolimus (RAD001) in Combination With Lenalidomide

    Not yet reported Emory University 44 participants Est. completion 2020-11-05 2 sites
    Other conditions: Solid Organ Malignancies, Adenoidcystic Carcinoma, Neuroendocrine Tumors
    View official trial listing →
  • Terminated NCT NCT01220297

    Sirolimus & Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related Donor HCT

    Not yet reported Stanford University 3 participants Est. completion 2011-08 1 site Stand-alone
    Other conditions: Hematologic Diseases, Acute-graft-versus-host Disease, Leukemia, Non-Hodgkin Lymphoma (NHL), Hodgkin Lymphoma
    View official trial listing →
  • Completed NCT NCT01220856

    Reparixin in Pancreatic Islet Transplantation

    Not yet reported Dompé Farmaceutici S.p.A 9 participants Est. completion 2013-04-30 2 sites
    Other conditions: Pancreatic Islet Transplantation in Type 1 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01222715

    Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma

    Not yet reported National Cancer Institute (NCI) 87 participants Est. completion 2015-06 184 sites
    Obstructive sleep apnea Other conditions: Recurrent Adult Soft Tissue Sarcoma
    View official trial listing →
  • Completed NCT NCT01223027

    Study of Dovitinib Versus Sorafenib in Patients With Metastatic Renal Cell Carcinoma

    Not yet reported Novartis Pharmaceuticals 564 participants Est. completion 2014-06 199 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Terminated NCT NCT01223755

    Sirolimus In Autosomal Dominant Polycystic Kidney Disease And Severe Renal Insufficiency

    Not yet reported, Not yet reported Mario Negri Institute for Pharmacological Research 41 participants Est. completion 2012-07 1 site Stand-alone
    Other conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)
    View official trial listing →
  • Suspended NCT NCT01226056

    Sorafenib in Combination With RAD001 in Advanced Solid Tumors Selected on Molecular Targets

    Not yet reported, Not yet reported Southern Europe New Drug Organization 45 participants Est. completion 2012-12 1 site
    Other conditions: Advanced Solid Tumors
    View official trial listing →
  • Status unknown NCT NCT01226355

    NOYA CoCr Biodegradable Coating Sirolimus-Eluting Coronary Stent System

    Not yet reported Medfavour (Beijing) Medical Co., Ltd 300 participants Est. completion 2014-11 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01229943

    Everolimus and Octreotide Acetate With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Neuroendocrine Tumors That Cannot Be Removed by Surgery

    Not yet reported National Cancer Institute (NCI) 150 participants Est. completion 2018-01-03 394 sites
    Other conditions: Advanced Pancreatic Neuroendocrine Tumor, Locally Advanced Pancreatic Neuroendocrine Tumor, Pancreatic Gastrinoma, Pancreatic Neuroendocrine Tumor G1, Pancreatic Neuroendocrine Tumor G2, Pancreatic Vipoma
    View official trial listing →
  • Completed NCT NCT01231399

    Everolimus and Combination Chemotherapy in Treating Patients With Metastatic Stomach or Esophageal Cancer

    Not yet reported, Not yet reported City of Hope Medical Center 6 participants Est. completion 2016-07 3 sites
    Other conditions: Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction, Diffuse Adenocarcinoma of the Stomach, Intestinal Adenocarcinoma of the Stomach, Mixed Adenocarcinoma of the Stomach, Recurrent Esophageal Cancer, Recurrent Gastric Cancer, Stage IV Esophageal Cancer, Stage IV Gastric Cancer
    View official trial listing →
  • Completed NCT NCT01231412

    Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

    Not yet reported Fred Hutchinson Cancer Center 174 participants Est. completion 2017-06-30 11 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Aggressive Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma, Hematopoietic and Lymphoid Cell Neoplasm, Indolent Non-Hodgkin Lymphoma, Mantle Cell Lymphoma, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Plasma Cell Myeloma, Refractory Chronic Lymphocytic Leukemia, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Hodgkin Lymphoma, Small Lymphocytic Lymphoma, T-Cell Chronic Lymphocytic Leukemia, Waldenstrom Macroglobulinemia
    View official trial listing →
  • Completed NCT NCT01231659

    Safety and Efficacy of RAD001 (Everolimus) in Combination With Letrozole in the Treatment of Postmenopausal Women With Locally Advanced or Metastatic Breast Cancer

    Not yet reported Novartis Pharmaceuticals 72 participants Est. completion 2017-04-30 7 sites
    Other conditions: Postmenopausal Women, Locally Advanced Metastatic Breast Cancer, Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT01233167

    Effect of Different Anti-platelet Strategies on the Long-term Outcome After Sirolimus Drug-eluting Stent Implantation

    Not yet reported Sir Run Run Shaw Hospital 5232 participants Est. completion 2013-05
    Cardiovascular disease
    View official trial listing →
  • Withdrawn NCT NCT01234974

    IGF-1 Inhibitor Pasireotide Lar in Combination With the m-TOR Inhibitor Everolimus

    Not yet reported Milton S. Hershey Medical Center Est. completion 2013-12 1 site
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT01236378

    Study To Evaluate Pharmacokinetics Of Sirolimus In Stable Renal Transplant Recipients

    Not yet reported Pfizer 24 participants Est. completion 2011-04 2 sites Stand-alone
    Other conditions: Transplant Rejection, Renal Transplantation
    View official trial listing →
  • Terminated NCT NCT01239342

    Akt Inhibitor MK2206 or Everolimus in Treating Patients With Refractory Kidney Cancer

    Not yet reported National Cancer Institute (NCI) 43 participants Est. completion 2018-09-19 8 sites
    Other conditions: Metastatic Kidney Carcinoma, Recurrent Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v7, Stage IV Renal Cell Cancer AJCC v7
    View official trial listing →
  • Terminated NCT NCT01239368

    Th1/Tc1 Immunotherapy Following Stem Cell Transplantation in Multiple Myeloma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 34 participants Est. completion 2017-08-16 2 sites
    Other conditions: Myeloma, Plasma-Cell, Myeloma-Multiple, Myelomatosis
    View official trial listing →
  • Completed NCT NCT01239472

    Cytokines Evaluation in Early Calcineurin Inhibitors Withdrawn on Renal Transplant

    Not yet reported Andre Barreto Pereira 30 participants Est. completion 2015-06 1 site
    Other conditions: Renal Transplant Rejection, Immunosuppression
    View official trial listing →
  • Completed NCT NCT01242306

    Comparison of Endothelial Dysfunction (BMS vs SES) in the Same Patient With Multiple Coronary Artery Lesions

    Not yet reported, Not yet reported Azienda Ospedaliera San Camillo Forlanini 25 participants Est. completion 2009-12 1 site
    Other conditions: Endothelial Dysfunction
    View official trial listing →
  • Completed NCT NCT01242631

    Everolimus for Patients With Relapsed/Refractory Germ Cell Cancer

    Not yet reported Hannover Medical School 25 participants Est. completion 2014-03 8 sites
    Other conditions: Testicular Cancer, Germ Cell Cancer
    View official trial listing →
  • Completed NCT NCT01244906

    Post-transplant Cyclophosphamide and Sirolimus Following Reduced Intensity Conditioning (RIC) Transplant

    Not yet reported Northside Hospital, Inc. 26 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Hematologic Neoplasms
    View official trial listing →
  • Status unknown NCT NCT01246817

    Temsirolimus-RCC-imaging

    Not yet reported Radboud University Medical Center 51 participants 1 site
    Other conditions: Renal Cell Cancer
    View official trial listing →
  • Completed NCT NCT01247428

    First-In-Human Trial of the MiStent Drug-Eluting Stent (DES) in Coronary Artery Disease

    Not yet reported Micell Technologies 30 participants Est. completion 2016-03 5 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01248403

    A Randomized, Double Blind Study Evaluating Paclitaxel With and Without RAD001 in Patients With Gastric Carcinoma After Prior Chemotherapy

    Not yet reported Krankenhaus Nordwest 300 participants Est. completion 2019-10 1 site
    Other conditions: Advanced Gastric Cancer, Esophagogastric Junction Cancer
    View official trial listing →
  • Completed NCT NCT01248494

    PhIb BKM120 or BEZ235+Endocrine Treatment in Post-Menopausal Patients With Hormone Receptor + Metastatic Breast Cancer

    Not yet reported Vanderbilt-Ingram Cancer Center 72 participants Est. completion 2016-05 6 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT01251458

    Hepatocellular Carcinoma (HCC)_Torisel_

    Not yet reported, Not yet reported Chinese University of Hong Kong 46 participants Est. completion 2016-01 1 site
    Other conditions: Inoperable HCC
    View official trial listing →
  • Completed NCT NCT01251575

    Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant

    Not yet reported Fred Hutchinson Cancer Center 77 participants Est. completion 2019-02-11 5 sites Stand-alone
    Other conditions: Adult Acute Lymphoblastic Leukemia, Adult Acute Myeloid Leukemia, Adult Diffuse Large B-Cell Lymphoma, Adult Myelodysplastic Syndrome, Adult Non-Hodgkin Lymphoma, Aggressive Non-Hodgkin Lymphoma, Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia, Childhood Diffuse Large B-Cell Lymphoma, Childhood Myelodysplastic Syndrome, Childhood Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia in Remission, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid Cell Neoplasm, Mantle Cell Lymphoma, Plasma Cell Myeloma, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, T-Cell Prolymphocytic Leukemia, Waldenstrom Macroglobulinemia, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Hodgkin Lymphoma
    View official trial listing →
  • Completed NCT NCT01252251

    RAD001 (Everolimus) and Pasireotide (SOM230) LAR in Patients With Advanced Uveal Melanoma

    Not yet reported Memorial Sloan Kettering Cancer Center 14 participants Est. completion 2016-06 1 site
    Other conditions: Uveal Melanoma
    View official trial listing →
  • Status unknown NCT NCT01255956

    Restenosis Treatment With Rapamycin Eluting Stent or Paclitaxel Eluting Balloon Catheter (RESTENOZA)

    Not yet reported Medical University of Warsaw 200 participants Est. completion 2012-07 4 sites
    Other conditions: In-Stent Restenosis
    View official trial listing →
  • Completed NCT NCT01256385

    Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous Therapy

    Not yet reported National Cancer Institute (NCI) 86 participants Est. completion 2013-12 24 sites
    Other conditions: Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Laryngeal Verrucous Carcinoma, Recurrent Lip and Oral Cavity Squamous Cell Carcinoma, Recurrent Metastatic Squamous Cell Carcinoma in the Neck With Occult Primary, Recurrent Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma, Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma, Recurrent Oral Cavity Verrucous Carcinoma, Recurrent Oropharyngeal Squamous Cell Carcinoma, Recurrent Salivary Gland Carcinoma, Salivary Gland Squamous Cell Carcinoma, Squamous Cell Carcinoma Metastatic in the Neck With Occult Primary, Stage IV Hypopharyngeal Squamous Cell Carcinoma, Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma, Stage IVA Laryngeal Squamous Cell Carcinoma, Stage IVA Laryngeal Verrucous Carcinoma, Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma, Stage IVA Major Salivary Gland Carcinoma, Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma, Stage IVA Oral Cavity Verrucous Carcinoma, Stage IVA Oropharyngeal Squamous Cell Carcinoma, Stage IVB Laryngeal Squamous Cell Carcinoma, Stage IVB Laryngeal Verrucous Carcinoma, Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma, Stage IVB Major Salivary Gland Carcinoma, Stage IVB Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma, Stage IVB Oral Cavity Verrucous Carcinoma, Stage IVB Oropharyngeal Squamous Cell Carcinoma, Stage IVC Laryngeal Squamous Cell Carcinoma, Stage IVC Laryngeal Verrucous Carcinoma, Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma, Stage IVC Major Salivary Gland Carcinoma, Stage IVC Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma, Stage IVC Oral Cavity Verrucous Carcinoma, Stage IVC Oropharyngeal Squamous Cell Carcinoma, Tongue Carcinoma
    View official trial listing →
  • Status unknown NCT NCT01257373

    Efficacy and Safety of Firebird 2 Stent in Treatment of Complex Coronary Lesions in Diabetes

    Xijing Hospital 1300 participants Est. completion 2013-04 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01259063

    RAD001 and Intravesical Gemcitabine in BCG-Refractory Primary or Secondary Carcinoma In Situ of the Bladder

    Not yet reported, Not yet reported Memorial Sloan Kettering Cancer Center 33 participants Est. completion 2017-06 1 site
    Other conditions: Bladder Cancer
    View official trial listing →
  • Status unknown NCT NCT01260558

    Test of Long-Term Safety and Efficacy of Sirolimus-Permanent-Polymer Eluting Stent (Cypher)- and Sirolimus-Polymer-free Eluting Stents (PPS/PFS) Assessed by Optical Coherence Tomography

    Not yet reported Deutsches Herzzentrum Muenchen 20 participants Est. completion 2012-12 2 sites
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT01262703

    Safety Study of a Bioresorbable Coronary Stent

    Not yet reported REVA Medical, Inc. 49 participants Est. completion 2018-12 1 site Stand-alone
    Cardiovascular disease Other conditions: Myocardial Ischemia, Coronary Artery Stenosis, Coronary Disease, Coronary Restenosis
    View official trial listing →
  • Completed NCT NCT01263353

    Safety and Tolerability of Pasireotide LAR in Combination With Everolimus in Advanced Metastatic NETs

    Not yet reported Novartis Pharmaceuticals 36 participants Est. completion 2014-03 4 sites
    Other conditions: Gastroenteropancreatic Neuroendocrine Tumor of the Pulmonary ot Gastroenteropancreatic System
    View official trial listing →
  • Status unknown NCT NCT01263951

    Study of Everolimus and Sorafenib in Patients With Advanced Thyroid Cancer Who Progressed on Sorafenib Alone

    Not yet reported Thomas Jefferson University 35 participants Est. completion 2022-05 1 site
    Other conditions: Differentiated Thyroid Cancer
    View official trial listing →
  • Terminated NCT NCT01264341

    Efficacy and Safety of Bevacizumab/Temsirolimus Combination to Treat Advanced Renal Cell Carcinoma

    Not yet reported Hellenic Cooperative Oncology Group 39 participants Est. completion 2015-07 8 sites
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT01265030

    A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis

    Not yet reported, Not yet reported MaineHealth 9 participants Est. completion 2021-12-22 8 sites Stand-alone
    Other conditions: Desmoid Tumor
    View official trial listing →
  • Completed NCT NCT01266057

    Sirolimus or Vorinostat and Hydroxychloroquine in Advanced Cancer

    Not yet reported M.D. Anderson Cancer Center 143 participants Est. completion 2021-02-11 1 site Stand-alone
    Other conditions: Advanced Cancers
    View official trial listing →
  • Completed NCT NCT01266148

    SCHEDULE - Scandinavian Heart Transplant Everolimus de Novo Study With Early Calcineurin Inhibitor (CNI) Avoidance

    Not yet reported Novartis Pharmaceuticals 115 participants Est. completion 2012-12 6 sites
    Other conditions: Renal Function and Chronic Allograft Vasculopathy
    View official trial listing →
  • Status unknown NCT NCT01266239

    Comparison Between Everolimus-eluting Stent (EES) and Sirolimus-eluting Stent (SES) in the Bifurcation Lesion

    Not yet reported Shin Yukuhashi Hospital 300 participants Est. completion 2015-07 5 sites
    Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Completed NCT NCT01266837

    Open Label, Single Arm Trial to Characterize Patients With Metastatic RCC Treated With Everolimus After Failure of the First VEGF-targeted Therapy (MARC-2)

    Not yet reported iOMEDICO AG 64 participants Est. completion 2017-10-31 8 sites
    Other conditions: Metastatic Renal Cell Carcinoma, Failure of Exactly One Prior VEGF-targeted Therapy
    View official trial listing →
  • Status unknown NCT NCT01268371

    Comparison of Biolimus-eluting Biodegradable Polymer, Everolimus-eluting and Sirolimus-eluting Coronary Stents

    Not yet reported Ajou University School of Medicine 1462 participants Est. completion 2015-07 26 sites
    Cardiovascular disease
    View official trial listing →
  • Withdrawn NCT NCT01269684

    Immediate Conversion From Tacrolimus to Everolimus in Stable Maintenance Renal Transplant Recipients

    Not yet reported Novartis Pharmaceuticals Est. completion 2008-08 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT01270321

    Pasireotide & Everolimus in Adult Patients With Radioiodine-Refractory Differentiated & Medullary Thyroid Cancer

    Not yet reported Emory University 42 participants Est. completion 2019-02 3 sites
    Other conditions: Thyroid Cancer
    View official trial listing →
  • Terminated NCT NCT01272141

    A Study of Lapatinib in Combination With Everolimus in Patients With Advanced, Triple Negative Breast Cancer

    Not yet reported Emory University 5 participants Est. completion 2014-01 3 sites
    Other conditions: Breast Neoplasms, Breast Cancer, Cancer of the Breast
    View official trial listing →
  • Completed NCT NCT01274234

    OCT Evaluation of Healing of COMBO Stent

    Not yet reported, Not yet reported Prof. Stephen Lee 61 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Coronary Restenosis, Coronary Thrombosis
    View official trial listing →
  • Completed NCT NCT01275222

    Everolimus in Combination With Imatinib in Patients With Glivec Refractory/Resistant Gastrointestinal Stromal Tumors

    Not yet reported, Not yet reported Novartis Pharmaceuticals 117 participants Est. completion 2008-09-03 16 sites
    Other conditions: Gastrointestinal Stromal Tumors
    View official trial listing →
  • Terminated NCT NCT01276834

    Comparison of Immunosuppression on Progression of Arteriosclerosis in Renal Transplantation

    Not yet reported Dianet Dialysis Centers 13 participants Est. completion 2012-07 1 site
    Other conditions: Renal Transplantation
    View official trial listing →
  • Withdrawn NCT NCT01280669

    Intravitreal Sirolimus as Therapeutic Approach to Uveitis

    Not yet reported Stanford University Est. completion 2024-12 1 site Stand-alone
    Other conditions: Uveitis, Intermediate Uveitis, Posterior Uveitis, Panuveitis
    View official trial listing →
  • Completed NCT NCT01281514

    A Study of Carboplatin, PLD and Everolimus in Certain Gynecologic Cancer

    Not yet reported Fox Chase Cancer Center 21 participants Est. completion 2018-01-08 1 site
    Other conditions: Fallopian Tube Cancer, Peritoneal Cavity Cancer, Recurrent Ovarian Epithelial Cancer
    View official trial listing →
  • Completed NCT NCT01281865

    Everolimus in Combination With Imatinib Mesylate in Treating Patients With Locally Advanced, Locally Recurrent, or Metastatic Soft Tissue Sarcoma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 14 participants Est. completion 2013-10 1 site
    Other conditions: Adult Synovial Sarcoma, Recurrent Adult Soft Tissue Sarcoma, Stage III Adult Soft Tissue Sarcoma, Stage IV Adult Soft Tissue Sarcoma
    View official trial listing →
  • Completed NCT NCT01281917

    Study of Velcade and Temsirolimus for Relapsed or Refractory Non-Hodgkin Lymphoma

    Not yet reported University of Wisconsin, Madison 40 participants Est. completion 2014-06 18 sites
    Other conditions: Non-Hodgkins Lymphoma
    View official trial listing →
  • Withdrawn NCT NCT01281943

    Study of Pegylated Liposomal Doxorubicin and Temsirolimus in Patients With Advanced Hepatocellular Cancer

    Not yet reported Washington University School of Medicine Est. completion 2014-05
    Other conditions: Liver Neoplasms
    View official trial listing →
  • Completed NCT NCT01282697

    Clinical Trial of Rapamycin and Irinotecan in Pediatric Patients With Refractory Solid Tumors

    Not yet reported University Hospital, Strasbourg, France 42 participants Est. completion 2013-02-20 9 sites
    Other conditions: Refractory Solid Tumors in Children
    View official trial listing →
  • Completed NCT NCT01283334

    A Study of Carboplatin, Cetuximab and RAD001 in Advanced Head and Neck Cancer

    Not yet reported, Not yet reported Emory University 20 participants Est. completion 2014-11 1 site
    Other conditions: Head and Neck Neoplasms, Cancer of the Head and Neck
    View official trial listing →
  • Status unknown NCT NCT01283789

    Lapatinib and RAD-001 for HER2 Positive Metastatic Breast Cancer

    Not yet reported University of Kansas Medical Center 23 participants Est. completion 2017-04 1 site
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT01289301

    Studying the Effect of Changing Immunosuppression in Case of Polyoma BK Virus Infection of the Renal Transplant

    Not yet reported Hannover Medical School 124 participants Est. completion 2018-10 4 sites
    Other conditions: Disorder Related to Renal Transplantation, Immunosuppression Related Infectious Disease, Virus Diseases
    View official trial listing →
  • Completed NCT NCT01289912

    Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC)

    Not yet reported Mustafa Sahin 52 participants Est. completion 2014-12 2 sites
    Other conditions: Tuberous Sclerosis Complex
    View official trial listing →
  • Completed NCT NCT01294748

    Clinical Investigation of the MiStent Drug Eluting Stent (DES) in Coronary Artery Disease

    Not yet reported Micell Technologies 184 participants Est. completion 2016-08 28 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01298713

    Tamoxifen-RAD001 Versus Tamoxifen Alone in Patients With Anti-aromatase Resistant Breast Metastatic Cancer

    Not yet reported ARCAGY/ GINECO GROUP 111 participants Est. completion 2018-09-12 1 site
    Other conditions: Breast Neoplasms, mTor Protein
    View official trial listing →
  • Terminated NCT NCT01303965

    Allo Transplant Followed by Lenalidomide and Sirolimus Maintenance in High-Risk Multiple Myeloma (MM)

    Not yet reported, Not yet reported Sherif S. Farag 14 participants Est. completion 2017-07-28 1 site Stand-alone
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Withdrawn NCT NCT01305395

    Strategies To Prevent Cardiac Allograft Vasculopathy Related Events in Heart Transplant Recipients

    Not yet reported University of Minnesota Est. completion 2015-01 1 site Stand-alone
    Other conditions: Cardiac Allograft Vasculopathy
    View official trial listing →
  • Completed NCT NCT01305941

    A Study Of Everolimus, Trastuzumab And Vinorelbine In HER2-Positive Breast Cancer Brain Metastases

    Not yet reported UNC Lineberger Comprehensive Cancer Center 32 participants Est. completion 2017-10-16 4 sites
    Other conditions: HER-2 Positive Breast Cancer
    View official trial listing →
  • No Longer Available NCT NCT01309022

    Immunosuppressive Medications for Participants in ITN005CT (NCT00014911)

    National Institute of Allergy and Infectious Diseases (NIAID) 3 sites
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Terminated NCT NCT01312064

    De Novo Everolimus-based Therapy for Renal Transplantation Using Rituximab Induction

    Not yet reported National Taiwan University Hospital 2 participants Est. completion 2012-04 1 site
    Other conditions: Renal Insufficiency
    View official trial listing →
  • Terminated NCT NCT01313390

    Everolimus and Docetaxel in Treating Patients With Recurrent, Locally Advanced, or Metastatic Head and Neck Cancer

    Not yet reported, Not yet reported University College, London 4 participants Est. completion 2011-04 1 site
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Terminated NCT NCT01313559

    Pasireotide (SOM230) With or Without Everolimus in Treating Patients With Hormone Resistant, Chemotherapy Naive Prostate Cancer

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 6 participants Est. completion 2012-11-29 2 sites
    Other conditions: Castrate Resistant Prostate Cancer, Chemotherapy Naive Prostate Cancer, Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT01313923

    Evaluating Sirolimus to Treat Autoimmune Blistering Dermatosis Pemphigus

    Not yet reported University of California, Irvine 3 participants Est. completion 2014-10 1 site Stand-alone
    Other conditions: Pemphigus
    View official trial listing →
  • Completed NCT NCT01316809

    AZD8055 for Adults With Recurrent Gliomas

    Not yet reported National Cancer Institute (NCI) 22 participants Est. completion 2016-04-04 1 site
    Other conditions: Glioblastoma Multiforme, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Malignant Glioma, Brainstem Glioma
    View official trial listing →
  • Completed NCT NCT01317615

    RAD001 With Paclitaxel and Carboplatin in First Line Treatment of Patients With Advanced Large Cell Lung Cancer With Neuroendocrine Differentiation

    Not yet reported Novartis Pharmaceuticals 49 participants Est. completion 2015-03 9 sites
    Other conditions: Carcinoma, Large Cell, Neuroendocrine Tumors
    View official trial listing →
  • Terminated NCT NCT01318915

    Research Study of ATG and Rituximab in Renal Transplantation

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 10 participants Est. completion 2017-08-25 6 sites Stand-alone
    Other conditions: Renal Transplant Recipients
    View official trial listing →
  • Completed NCT NCT01324492

    Safety and Efficacy of RAD001 in Chinese Patients With Advanced Pulmonary Neuroendocrine Tumor

    Not yet reported Novartis Pharmaceuticals 16 participants Est. completion 2014-06 4 sites
    Other conditions: Lung Neuroendocrine Neoplasm
    View official trial listing →
  • Withdrawn NCT NCT01326468

    Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University Est. completion 2016-12
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Withdrawn NCT NCT01328730

    The Real-world Firebird 2 Versus Cypher Sirolimus-eluting Stent in Treating Patients With Coronary Artery Disease

    Not yet reported Shanghai Jiao Tong University School of Medicine 430 participants Est. completion 2013-06 1 site
    Other conditions: Coronary Artery Stenosis
    View official trial listing →
  • Completed NCT NCT01331135

    Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors

    Not yet reported Emory University 18 participants Est. completion 2017-08-09 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Ewing's Sarcoma, Astrocytoma, Atypical Teratoid/Rhabdoid Tumor, Ependymoma, Germ Cell Tumor, Glioma, Medulloblastoma, Rhabdoid Tumor, Retinoblastoma, Clear Cell Sarcoma, Renal Cell Carcinoma, Wilms Tumor, Hepatoblastoma, Neuroblastoma
    View official trial listing →
  • Withdrawn NCT NCT01332279

    Everolimus, Erlotinib Hydrochloride, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer Previously Treated With Radiation Therapy

    Not yet reported Fox Chase Cancer Center Est. completion 2011-05 1 site
    Other conditions: Recurrent Metastatic Squamous Neck Cancer With Occult Primary, Recurrent Salivary Gland Cancer, Recurrent Squamous Cell Carcinoma of the Hypopharynx, Recurrent Squamous Cell Carcinoma of the Larynx, Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity, Recurrent Squamous Cell Carcinoma of the Oropharynx, Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Recurrent Verrucous Carcinoma of the Larynx, Recurrent Verrucous Carcinoma of the Oral Cavity, Salivary Gland Squamous Cell Carcinoma, Tongue Cancer
    View official trial listing →
  • Completed NCT NCT01333085

    Everolimus, Carboplatin, and Paclitaxel in Locally Advanced Head and Neck Cancer That Cannot Be Removed by Surgery

    Not yet reported, Not yet reported GERCOR - Multidisciplinary Oncology Cooperative Group 49 participants Est. completion 2013-05 5 sites
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Completed NCT NCT01334073

    Study of the Combination of Axitinib Plus Everolimus in Patients With Malignant Advanced Solid Tumors

    Not yet reported University Hospital, Bordeaux 19 participants Est. completion 2015-01 2 sites
    Other conditions: Malignant Advanced Solid Tumors, Carcinoma, Renal Cell
    View official trial listing →
  • Completed NCT NCT01334502

    Everolimus, Rituximab, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Untreated Diffuse Large B-Cell Lymphoma

    Not yet reported Alliance for Clinical Trials in Oncology 26 participants Est. completion 2017-08 1 site
    Other conditions: Lymphoma
    View official trial listing →
  • Withdrawn NCT NCT01335074

    Temsirolimus + Sorafenib in Advanced Hepatocellular Carcinoma (HCC)

    Not yet reported, Not yet reported Philipps University Marburg 1 site
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT01337765

    Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor Patients

    Not yet reported Pfizer 29 participants Est. completion 2013-03-22 6 sites
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific, Solid Tumor
    View official trial listing →
  • Completed NCT NCT01338090

    89Zr-bevacizumab PET Imaging in Patients With Neuroendocrine Tumors

    University Medical Center Groningen 14 participants Est. completion 2012-03 1 site
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Status unknown NCT NCT01341834

    Safety and Tolerability Study of RAD001 and LBH589 in All Solid Tumors With Enrichment for EBV Driven Tumors

    Not yet reported National Cancer Centre, Singapore 49 participants Est. completion 2018-12 1 site
    Other conditions: Nasopharyngeal Carcinoma, Lymphomas, Any EBV+ Solid Tumour
    View official trial listing →
  • Completed NCT NCT01343498

    Study of PI3 Kinase/mTOR Inhibitor BEZ235 Twice Daily for Advanced Solid Tumors

    Not yet reported SCRI Development Innovations, LLC 33 participants Est. completion 2014-01 2 sites
    Other conditions: Malignant Solid Tumour
    View official trial listing →
  • Terminated NCT NCT01345136

    Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma

    Not yet reported Jonsson Comprehensive Cancer Center 4 participants Est. completion 2024-02-06 1 site
    Other conditions: Neurofibromatosis Type 2, Neuroma, Acoustic
    View official trial listing →
  • Completed NCT NCT01346085

    Calcineurin Inhibitor (CNI)-Free Immunosuppressive Regimen in T1D Patients Receiving Islet Transplantation

    Not yet reported, Not yet reported Ospedale San Raffaele 10 participants Est. completion 2012-06 2 sites
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Terminated NCT NCT01347866

    Clinical Study Of PI3K/mTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced Cancer

    Not yet reported Pfizer 105 participants Est. completion 2015-12 18 sites
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT01349296

    BIBF 1120 and RAD001 in Solid Tumors - Phase I

    Not yet reported University of Cologne 18 participants Est. completion 2016-05 1 site
    Other conditions: Solid Tumors
    View official trial listing →
  • Completed NCT NCT01353625

    Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies.

    Not yet reported Celgene 118 participants Est. completion 2021-03-12 17 sites
    Obstructive sleep apnea Other conditions: Glioblastoma Multiforme, Squamous Cell Carcinoma of Head and Neck, Prostate Cancer, Chronic Lymphocytic Leukemia, Neoplasm Metastasis
    View official trial listing →
  • Completed NCT NCT01354301

    Efficacy and Safety of Induction Strategies Combined With Low Tacrolimus Exposure in Kidney Transplant Recipients Receiving Everolimus or Sodium Mycophenolate

    Not yet reported Hospital do Rim e Hipertensão 300 participants Est. completion 2014-12 1 site
    Other conditions: Cytomegalovirus Infection, Renal Transplant Failure, Transplant; Complication, Rejection
    View official trial listing →
  • Completed NCT NCT01358266

    Study Assessing Double-masked Uveitis Treatment

    Not yet reported Santen Inc. 592 participants Est. completion 2016-12 151 sites
    Other conditions: Uveitis; Posterior, Disorder
    View official trial listing →
  • Completed NCT NCT01363752

    A Study Looking at Kidney Function in Kidney Transplant Recipients Who Are Taking Anti-rejection Medication Including Tacrolimus and With or Without Sirolimus.

    Not yet reported Astellas Pharma Inc 853 participants Est. completion 2013-09-18 58 sites Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT01364844

    Safety and Tolerability of DS-7423 in Subjects With Advanced Solid Malignant Tumors

    Not yet reported Daiichi Sankyo 42 participants Est. completion 2013-11 3 sites
    Other conditions: Solid Tumor, Colorectal Cancer, Endometrial Cancer
    View official trial listing →
  • Terminated NCT NCT01365468

    Efficacy and Safety of RAD001 in Treating Plexiform Neurofibromas (PN) Associated With Neurofibromatosis (NF1)

    Not yet reported Novartis Pharmaceuticals 9 participants Est. completion 2015-04 2 sites
    Other conditions: Plexiform Neurofibroma Associated With Neurofibromatosis Type 1
    View official trial listing →
  • Completed NCT NCT01367457

    INHIBITOR: Retrospective Study Of Patients With Renal Cell Carcinoma And Mantle Cell Lymphoma Treated With Temsirolimus

    Pfizer 243 participants Est. completion 2015-04 16 sites
    Other conditions: Carcinoma, Renal Cell, Lymphoma, Mantle-Cell
    View official trial listing →
  • Completed NCT NCT01368627

    The E-SERIES Registry for Supralimus® Coronary Stent for the Treatment of Unselected Patients With Coronary Lesions

    Not yet reported Sahajanand Medical Technologies Limited 1274 participants Est. completion 2011-12 7 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT01369433

    A Rollover Protocol to Allow Continued Access to Tivozanib (AV 951) for Subjects Enrolled in Other Tivozanib Protocols

    Not yet reported AVEO Pharmaceuticals, Inc. 225 participants Est. completion 2015-10 49 sites
    Other conditions: Solid Tumors
    View official trial listing →
  • Status unknown NCT NCT01373632

    Firebird 2 Versus Excel Sirolimus-eluting Stent in Treating Real-world Patients With Coronary Artery Disease

    Not yet reported Shanghai Jiao Tong University School of Medicine 570 participants Est. completion 2013-09 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT01374451

    Efficacy of Everolimus Alone or in Combination With Pasireotide LAR in Advanced PNET

    Not yet reported Novartis Pharmaceuticals 160 participants Est. completion 2015-02 47 sites
    Other conditions: Islet Cell Tumor
    View official trial listing →
  • Completed NCT NCT01374750

    Efficacy of Sirolimus In Liver Transplantation for Hepatocellular Carcinoma (HCC)

    Not yet reported Seoul National University Hospital 45 participants Est. completion 2016-05 1 site Stand-alone
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Status unknown NCT NCT01375296

    China Made Sirolimus Eluting Stent for Intermediate Lesion

    Not yet reported, Not yet reported Shanghai Jiao Tong University School of Medicine 600 participants Est. completion 2011-11 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT01375829

    Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

    Not yet reported National Cancer Institute (NCI) 22 participants Est. completion 2027-03-19 2 sites
    Other conditions: Adult Solid Neoplasm
    View official trial listing →
  • Terminated NCT NCT01376310

    GSK1120212 Rollover Study

    Not yet reported Novartis Pharmaceuticals 159 participants Est. completion 2018-01-18 19 sites
    Other conditions: Cancer
    View official trial listing →
  • Terminated NCT NCT01378377

    Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus

    Not yet reported EMD Serono 33 participants Est. completion 2012-02-23 3 sites
    Other conditions: Advanced Solid Tumor
    View official trial listing →
  • Completed NCT NCT01379209

    Intravenous Administration of RGI-2001 in Patient Undergoing Allogenic Hematopoietic Stem Cell Transplantation (AHSCT)

    Not yet reported, Not yet reported Regimmune Corporation 68 participants Est. completion 2017-04 6 sites Stand-alone
    Other conditions: Graft Versus Host Disease
    View official trial listing →
  • Terminated NCT NCT01379521

    Safety and Efficacy of RAD001 + TACE in Localized Unresectable HCC

    Not yet reported Novartis Pharmaceuticals 65 participants Est. completion 2015-06 5 sites
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT01381692

    Bortezomib, Rituximab, and Dexamethasone With or Without Temsirolimus in Treating Patients With Untreated or Relapsed Waldenstrom Macroglobulinemia or Relapsed or Refractory Mantle Cell or Follicular Lymphoma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 9 participants Est. completion 2021-09-01 11 sites
    Other conditions: Recurrent Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Non-Hodgkin Lymphoma, Recurrent Small Lymphocytic Lymphoma, Recurrent Waldenstrom Macroglobulinemia, Refractory Follicular Lymphoma, Refractory Mantle Cell Lymphoma, Refractory Marginal Zone Lymphoma, Refractory Non-Hodgkin Lymphoma, Refractory Small Lymphocytic Lymphoma
    View official trial listing →
  • Completed NCT NCT01382043

    Angiographic and IVUS Follow-up After Simultaneously Implanted Different Drug-eluting Stents in Same Individuals (AIFSIDDES)

    Liuhuaqiao Hospital 48 participants Est. completion 2011-01 1 site
    Other conditions: Percutaneous Coronary Angioplasty
    View official trial listing →
  • Withdrawn NCT NCT01383668

    Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung Cancer

    Not yet reported Mayo Clinic Est. completion 2013-02-08 Stand-alone
    Other conditions: Recurrent Non-small Cell Lung Cancer, Squamous Cell Lung Cancer, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT01387880

    Irinotecan, Cetuximab and Everolimus to Patients With Metastatic Colorectal Cancer

    Not yet reported Herlev Hospital 100 participants Est. completion 2012-03 1 site
    Other conditions: Metastatic Colorectal Cancer
    View official trial listing →
  • Completed NCT NCT01389427

    Escalating Doses of Torisel in Combination With Three Chemotherapies Regimens: R-CHOP, R-FC or R-DHA for Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL).

    Not yet reported, Not yet reported The Lymphoma Academic Research Organisation 41 participants Est. completion 2015-09 11 sites
    Other conditions: Mantle Cell Lymphoma Refractory
    View official trial listing →
  • Completed NCT NCT01390519

    A Norwegian Observational Trial Evaluating the Treatment of Advanced Renal Cell Cancer Patients Under Treatment of Afinitor

    Novartis Pharmaceuticals 30 participants Est. completion 2015-12 3 sites
    Other conditions: Metastatic Renal Cell Carcinoma (mRCC)
    View official trial listing →
  • Completed NCT NCT01390818

    Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors

    Not yet reported EMD Serono 146 participants Est. completion 2015-04 8 sites
    Other conditions: Locally Advanced Solid Tumor, Metastatic Solid Tumor, Breast Cancer, Non Small Cell Lung Cancer, Melanoma, Colorectal Cancer
    View official trial listing →
  • Completed NCT NCT01392183

    Pazopanib Versus Temsirolimus in Poor-Risk Clear-Cell Renal Cell Carcinoma (RCC)

    Not yet reported M.D. Anderson Cancer Center 69 participants Est. completion 2019-09-08 1 site
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT01396200

    Cyclophosphamide and Pulse Dexamethasone With Rapamycin or Hydroxychloroquine

    Not yet reported Abramson Cancer Center at Penn Medicine 6 participants Est. completion 2012-10 1 site
    Other conditions: Myeloma
    View official trial listing →
  • Active, not recruiting NCT NCT01396408

    A Phase II Study of Sunitinib or Temsirolimus in Patients With Advanced Rare Tumours

    Not yet reported Canadian Cancer Trials Group 137 participants Est. completion 2026-12-31 17 sites
    Other conditions: Advanced Rare Tumours
    View official trial listing →
  • Completed NCT NCT01398306

    Biomarkers for Angiogenesis in Renal Cell Carcinoma and Neuro-endocrine Tumours.

    University Medical Center Groningen 40 participants Est. completion 2012-04 1 site
    Other conditions: Carcinoma, Carcinoma, Renal Cell, Neuroendocrine Tumors, Carcinoid Tumor, Pancreatic Islet Cell Tumors
    View official trial listing →
  • Status unknown NCT NCT01399242

    Efficacy of Certican® in Combination With Myfortic® in Renal

    Not yet reported Hospital Universitário São José 40 participants Est. completion 2013-06 1 site
    Other conditions: Disorder Related to Renal Transplantation
    View official trial listing →
  • Completed NCT NCT01399918

    Everolimus and Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma (RCC)

    Not yet reported Memorial Sloan Kettering Cancer Center 57 participants Est. completion 2020-12-28 7 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01403415

    Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

    Not yet reported National Cancer Institute (NCI) 13 participants 31 sites
    Other conditions: Childhood B Acute Lymphoblastic Leukemia, Childhood T Acute Lymphoblastic Leukemia, Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Lymphoblastic Lymphoma
    View official trial listing →
  • Completed NCT NCT01404104

    Neo-adjuvant Temsirolimus in Patients With Advanced Renal Cell Carcinoma

    Not yet reported St. Joseph's Healthcare Hamilton 11 participants Est. completion 2014-08 1 site
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01404325

    Efficacy Regarding Renal Function of Everolimus in Combination With Specific Standard Immunosuppressive Regimen Lung Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 130 participants Est. completion 2017-01-05 9 sites
    Other conditions: Lung Transplantation
    View official trial listing →
  • Completed NCT NCT01405287

    Study of Vascular Healing With the Combo Stent Versus the Everolimus Eluting Stent in ACS Patients by Means of OCT

    Not yet reported OrbusNeich 60 participants Est. completion 2014-01 6 sites
    Cardiovascular disease Other conditions: Atherosclerosis, Acute Coronary Syndrome (ACS)
    View official trial listing →
  • Completed NCT NCT01408004

    Rotating Pazopanib and Everolimus to Avoid Resistance

    Not yet reported Netherlands Working Group on Immunotherapy of Oncology 101 participants Est. completion 2014-04 17 sites
    Other conditions: Clear Cell Renal Carcinoma
    View official trial listing →
  • Completed NCT NCT01410448

    Everolimus in de Novo Kidney Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 383 participants Est. completion 2015-12 22 sites
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT01412164

    Observational Registry Study: FIREHAWK DES for Treating Coronary Artery Disease (CAD)

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 730 participants Est. completion 2017-01 1 site
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT01412515

    A Phase II Study With Tumor Molecular Pharmacodynamic (MPD) Evaluation of Oral mTOR-inhibitor Everolimus (RAD001) 10 mg Daily in Patients Suffering From Classic or Endemic Kaposi's Sarcoma

    Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 11 participants Est. completion 2011-05 1 site
    Other conditions: Kaposi Sarcoma
    View official trial listing →
  • Completed NCT NCT01412892

    Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas

    Not yet reported Assistance Publique - Hôpitaux de Paris 30 participants Est. completion 2014-10 1 site
    Other conditions: Neurofibromatosis Type 1, Plexiform Neurofibroma, Neurofibromatoses
    View official trial listing →
  • Completed NCT NCT01417065

    Temsirolimus In Phase 0

    Not yet reported M.D. Anderson Cancer Center 15 participants 1 site
    Other conditions: Advanced Cancer
    View official trial listing →
  • Status unknown NCT NCT01418794

    Efficacy and Safety of the YUKON Drug Eluting Stent in Diffuse Coronary Artery Disease

    Not yet reported Shenyang Northern Hospital 606 participants 4 sites
    Other conditions: Acute Coronary Syndromes
    View official trial listing →
  • Completed NCT NCT01419639

    Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2

    Not yet reported NYU Langone Health 10 participants Est. completion 2013-12 1 site
    Other conditions: Neurofibromatosis Type II
    View official trial listing →
  • Terminated NCT NCT01420081

    A Study Of Two Dual PI3K/mTOR Inhibitors, PF-04691502 And PF-05212384 In Patients With Recurrent Endometrial Cancer

    Not yet reported Pfizer 67 participants Est. completion 2015-12-25 51 sites
    Other conditions: Endometrial Neoplasms
    View official trial listing →
  • Status unknown NCT NCT01423708

    Everolimus in de Novo Liver Transplantation: a Multicentre Randomized Study

    Not yet reported Azienda Ospedaliera di Padova 117 participants Est. completion 2014-01 7 sites
    Other conditions: Liver Failure, Liver Diseases, Liver Cirrhosis, Liver Neoplasms
    View official trial listing →
  • Completed NCT NCT01427946

    Phase 1b/2 Study of Retaspimycin HCl (IPI-504) in Combination With Everolimus in KRAS Mutant Non-small Cell Lung Cancer

    Not yet reported, Not yet reported Infinity Pharmaceuticals, Inc. 47 participants Est. completion 2014-10 5 sites
    Other conditions: Non-small Cell Lung Cancer
    View official trial listing →
  • Status unknown NCT NCT01428973

    Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis Regimens

    Not yet reported University of Liege 200 participants Est. completion 2024-12 13 sites Stand-alone
    Other conditions: Graft-Versus-Host Disease, Hematological Malignancies
    View official trial listing →
  • Completed NCT NCT01430572

    Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients

    Not yet reported M.D. Anderson Cancer Center 62 participants Est. completion 2020-05-12 1 site
    Other conditions: Advanced Cancers, Solid Tumors
    View official trial listing →
  • Completed NCT NCT01434602

    Phase I-II Everolimus and Sorafenib in Recurrent High-Grade Gliomas

    Not yet reported, Not yet reported National Cancer Institute (NCI) 86 participants Est. completion 2021-07-13 1 site
    Other conditions: Brain Tumor, Glioblastoma, Anaplastic Glioma
    View official trial listing →
  • Completed NCT NCT01442090

    Study of GDC-0980 Versus Everolimus in Participants With Metastatic Renal Cell Carcinoma Who Have Progressed on or Following Vascular Endothelial Growth Factor- (VEGF) Targeted Therapy

    Not yet reported Genentech, Inc. 85 participants Est. completion 2015-07 22 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01443104

    Sirolimus-eluting Stents With Biodegradable Polymer Versus an Everolimus-eluting Stents

    Not yet reported Insel Gruppe AG, University Hospital Bern 2119 participants Est. completion 2018-06 9 sites
    Cardiovascular disease Other conditions: Angina Pectoris
    View official trial listing →
  • Terminated NCT NCT01443754

    Hybrid Revascularisation by Combined Coronary Artery Bypass Graft (CABG) and PCI in Multivessel Coronary Disease

    Ettore Sansavini Health Science Foundation 50 participants Est. completion 2016-04 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01445106

    A Phase I Trial of Nelfinavir (Viracept ) in Adults With Solid Tumors

    Not yet reported National Cancer Institute (NCI) 28 participants Est. completion 2011-05-09 1 site
    Other conditions: Solid Tumors
    View official trial listing →
  • Completed NCT NCT01445548

    Sirolimus for Advanced Age-Related Macular Degeneration

    Not yet reported, Not yet reported National Eye Institute (NEI) 6 participants Est. completion 2014-02 1 site Stand-alone
    Other conditions: Age-Related Macular Degeneration, Geographic Atrophy
    View official trial listing →
  • Status unknown NCT NCT01446484

    Treatment of Children With Kidney Transplants by Injection of CD4+CD25+FoxP3+ T Cells to Prevent Organ Rejection

    Not yet reported, Not yet reported Pirogov Russian National Research Medical University 30 participants Est. completion 2014-11 2 sites Stand-alone
    Other conditions: End-Stage Renal Disease, Kidney Failure
    View official trial listing →
  • Completed NCT NCT01451879

    Observational Study for Subjects With Pompe Disease Undergoing Immune Modulation Therapies

    University of Florida 11 participants Est. completion 2017-10 1 site
    Other conditions: Pompe Disease
    View official trial listing →
  • Terminated NCT NCT01453140

    In-vivo Regulatory T Cell Enhancement With Cyclophosphamide and Sirolimus

    Not yet reported, Not yet reported Hackensack Meridian Health 3 participants Est. completion 2012-07 1 site Stand-alone
    Other conditions: Graft Versus Host Disease
    View official trial listing →
  • Completed NCT NCT01453504

    Everolimus in Combination With DHAP in Patients With Relapsed or Refractory Hodgkin Lymphoma

    Not yet reported, Not yet reported University of Cologne 73 participants Est. completion 2019-03 1 site
    Other conditions: Hodgkin Lymphoma
    View official trial listing →
  • Status unknown NCT NCT01455649

    Study to Evaluate the Safety and Efficacy of Switching Calcineurin Inhibitor to Everolimus After Kidney Transplantation in Adults

    Not yet reported Deise de Boni Monteiro de Carvalho 30 participants Est. completion 2013-11 1 site
    Other conditions: Kidney Transplant, Immunosuppression
    View official trial listing →
  • Completed NCT NCT01460420

    Sequential Trial on Reduced Intensity Conditioning (RIC) Allogeneic Transplantation

    Not yet reported, Not yet reported European Myeloma Network B.V. 49 participants Est. completion 2017-06-29 10 sites Stand-alone
    Other conditions: Hematologic Malignancies, Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT01460979

    Efficacy,Tolerability,Safety of Temsirolimus in Women With Platinum-refractory Ovarian Carcinoma or Advanced Endometrial Carcinoma

    Not yet reported AGO Study Group 47 participants Est. completion 2015-11 18 sites
    Other conditions: Genital Diseases, Female, Ovarian Diseases, Ovarian Neoplasms, Endometrial Neoplasms
    View official trial listing →
  • Completed NCT NCT01462006

    Double-blind Placebo-controlled Pilot Study of Sirolimus in Idiopathic Pulmonary Fibrosis (IPF)

    Not yet reported University of Virginia 32 participants Est. completion 2016-03 1 site Stand-alone
    Other conditions: Idiopathic Pulmonary Fibrosis, Diffuse Parenchymal Lung Disease, Interstitial Lung Disease
    View official trial listing →
  • Completed NCT NCT01462214

    Study of Everolimus and Low-dose Cyclophosphamide in Patients With Metastatic Renal Cell Cancer

    Not yet reported, Not yet reported Hans J. van der Vliet, MD, PhD 96 participants Est. completion 2017-01 13 sites
    Other conditions: Metastatic Renal Cell Cancer
    View official trial listing →
  • Completed NCT NCT01466231

    Everolimus in Refractory Testicular Germ Cell Cancer

    Not yet reported National Cancer Institute, Slovakia 15 participants Est. completion 2015-06 1 site
    Other conditions: Germ Cell Tumor
    View official trial listing →
  • Completed NCT NCT01467986

    Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma

    Not yet reported University of Regensburg 130 participants Est. completion 2020-09-30 1 site
    Other conditions: Neuroblastoma Recurrent
    View official trial listing →
  • Completed NCT NCT01469572

    Pasireotide, Everolimus and Selective Internal Radioembolization Therapy for Unresectable Hepatic Metastases

    Not yet reported Emory University 13 participants Est. completion 2018-10 1 site
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Completed NCT NCT01469884

    Effect of Switching to Certican® in Viremia of Hepatitis C Virus in Adult Renal Allograft Recipients

    Not yet reported Irmandade Santa Casa de Misericórdia de Porto Alegre 30 participants Est. completion 2015-04 1 site
    Other conditions: Renal Allograft, Hepatitis C
    View official trial listing →
  • Completed NCT NCT01470209

    A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies

    Not yet reported Emory University 43 participants Est. completion 2017-05 1 site
    Other conditions: Solid Tumors, Lung Cancer
    View official trial listing →
  • Completed NCT NCT01472705

    Everolimus- Versus Biolimus-Eluting Stents in All-Comers

    University of Freiburg 814 participants Est. completion 2011-11 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01473095

    Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma

    Not yet reported ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA) 120 participants Est. completion 2017-08-07 7 sites
    Other conditions: Solid Tumor, Malignant Lymphoma, Tumor
    View official trial listing →
  • Terminated NCT NCT01473732

    Mechanisms and Treatment of Chronic Allograft Injury (CAI) Due to Calcineurin Inhibitor (CNI) Toxicity

    Not yet reported Montefiore Medical Center 2 participants Est. completion 2012-08 1 site
    Other conditions: Chronic Allograft Injury, Calcineurin Inhibitor Toxicity
    View official trial listing →
  • Completed NCT NCT01482156

    Dose Finding Study of RAD001 (Everolimus, Afinitor®) in Combination With BEZ235 in Patients With Advanced Solid Tumors

    Not yet reported Novartis Pharmaceuticals 46 participants Est. completion 2015-02 10 sites
    Other conditions: Advanced Solid Tumors, Metastatic Breast Cancer, Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01482299

    RAD001 in Advanced Gastric Cancer Who Failed Standard First-line Treatment With pS6 Ser 240/4 Expression

    Not yet reported Asan Medical Center 45 participants Est. completion 2014-01 1 site
    Other conditions: Stomach Neoplasm
    View official trial listing →
  • Terminated NCT NCT01488253

    Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell Transplants

    Not yet reported The Korean Society of Blood and Marrow Transplantation 3 participants Est. completion 2014-10 1 site Stand-alone
    Other conditions: Acute Leukemia in Remission, Myelodysplastic Syndromes, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Accelerated-Phase
    View official trial listing →
  • Completed NCT NCT01488487

    Everolimus and Pasireotide (SOM230) in Patients With Advanced or Metastatic Hepatocellular Carcinoma

    Not yet reported UNC Lineberger Comprehensive Cancer Center 24 participants Est. completion 2015-03 3 sites
    Other conditions: Advanced Adult Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT01490476

    Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) Patients

    Not yet reported Assistance Publique - Hôpitaux de Paris 10 participants Est. completion 2017-01 1 site
    Other conditions: Neurofibromatosis 2
    View official trial listing →
  • Completed NCT NCT01490749

    Trial of XELOX Followed by Radiation Combined With Carboplatin and RAD001 for Esophageal Cancer

    Not yet reported Emory University 17 participants Est. completion 2019-02 3 sites
    Other conditions: Esophageal Cancer, Neoplasms, Esophageal
    View official trial listing →
  • Completed NCT NCT01491672

    Everolimus as Second-line Therapy in Metastatic Renal Cell Carcinoma

    Not yet reported Novartis Pharmaceuticals 134 participants Est. completion 2015-05 17 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Withdrawn NCT NCT01492894

    Kidney Allograft Dysfunction Without Reversible Causes

    Not yet reported University of Minnesota Est. completion 2011-10 1 site
    Other conditions: Kidney Graft Dysfunction
    View official trial listing →
  • Terminated NCT NCT01495247

    Phase Ib/II Trial of BEZ235 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer

    Not yet reported, Not yet reported Novartis Pharmaceuticals 18 participants Est. completion 2014-05-19 3 sites
    Other conditions: Inoperable Locally Advanced Breast Cancer, Metastatic Breast Cancer (MBC)
    View official trial listing →
  • Terminated NCT NCT01499160

    Letrozole and Lapatinib Followed by Everolimus in Women With Advanced Breast Cancer

    Not yet reported University of Maryland, Baltimore 7 participants Est. completion 2016-12 1 site
    Other conditions: Breast Neoplasms, Endocrine Breast Diseases, Neoplasm Metastasis
    View official trial listing →
  • Completed NCT NCT01502904

    Neointimal Coverage After Implantation of Biolimus Eluting Stent With Biodegradable Polymer: Optical Coherence Tomographic Assessment According to the Treatment of Dyslipidemia and Hypertension and the Types of Implanted Drug-eluting Stents

    Not yet reported Yonsei University 120 participants Est. completion 2015-06 1 site
    Other conditions: Stable Angina or Acute Coronary Syndrome Considered for Percutaneous Coronary Intervention With Dyslipidemia or Hypertension
    View official trial listing →
  • Completed NCT NCT01507519

    Study Safety and Performance of the Biomime Stent in Patients With Single, De Novo, Non-Complex Coronary Lesions

    Not yet reported Meril Life Sciences Pvt. Ltd. 30 participants Est. completion 2011-03 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT01508104

    Safety Study of BEZ235 With Everolimus in Subjects With Advanced Solid Tumors

    Not yet reported University of Cincinnati 19 participants Est. completion 2014-12 1 site
    Other conditions: Cancer
    View official trial listing →
  • Completed NCT NCT01509560

    PhaseII,Open-label,Pilot Study Evaluating the Safety+Efficacy of Certican ® in the Prevention of Chronic Graft-versus-host Disease+Late Pulmonary Complications After Allogeneic Hematopoietic Cell Transplantation Blood

    Not yet reported Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH 21 participants Est. completion 2016-04-30 1 site
    Other conditions: Condition After Allogenic Peripheral Stem Cell Transplantation (SCT)
    View official trial listing →
  • Completed NCT NCT01510119

    Autophagy Inhibition to Augment Mammilian Target of Rapamycin (mTOR) Inhibition: A Phase I/II Trial of RAD001 and Hydroxychloroquine (HCQ) in Patients With Previously Treated Renal Cell Carcinoma

    Not yet reported, Not yet reported Abramson Cancer Center at Penn Medicine 40 participants Est. completion 2017-01-05 3 sites
    Other conditions: Metastatic Clear Cell Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01514110

    Gastric Cancer RAD001 Study

    Not yet reported, Not yet reported Chinese University of Hong Kong 35 participants Est. completion 2019-03-06 1 site
    Other conditions: Gastric Cancer
    View official trial listing →
  • Completed NCT NCT01514448

    Safety and Efficacy of Everolimus in Metastatic Renal Cell Carcinoma After Failure of First Line Therapy With Sunitinib or Pazopanib

    Not yet reported Novartis Pharmaceuticals 29 participants Est. completion 2016-04-01 13 sites
    Other conditions: Metastatic Renal Cell Carcinoma (mRCC)
    View official trial listing →
  • Completed NCT NCT01516723

    Hybrid Sirolimus-eluting Versus Everolimus-eluting Stents for Total Coronary Occlusions

    Not yet reported R&D Cardiologie 330 participants Est. completion 2020-12-31 4 sites Stand-alone
    Cardiovascular disease Other conditions: Coronary Disease, Coronary Stenosis
    View official trial listing →
  • Completed NCT NCT01517074

    Sirolimus Injections for Autoimmune Scleritis

    Not yet reported, Not yet reported National Eye Institute (NEI) 5 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: Scleritis
    View official trial listing →
  • Completed NCT NCT01517243

    Phase II Study of Alternating Sunitinib and Temsirolimus

    Not yet reported Dartmouth-Hitchcock Medical Center 37 participants Est. completion 2018-08-20 2 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01520103

    Study to Compare Vinorelbine In Combination With the mTOR Inhibitor Everolimus vs. Vinorelbin Monotherapy for Second-line Treatment in Advanced Breast Cancer

    Not yet reported AIO-Studien-gGmbH 139 participants Est. completion 2016-10-31 1 site
    Other conditions: Her2-negative Metastatic Breast Cancer, Her2-negative Locally Advanced Breast Cancer
    View official trial listing →
  • Completed NCT NCT01522820

    Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors

    Not yet reported Roswell Park Cancer Institute 18 participants Est. completion 2016-07 1 site Stand-alone
    Other conditions: Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma, Estrogen Receptor Negative, Estrogen Receptor Positive, Glioblastoma, Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma, Metastatic Renal Cell Cancer, Recurrent Adult Brain Neoplasm, Recurrent Bladder Carcinoma, Recurrent Breast Carcinoma, Recurrent Colorectal Carcinoma, Recurrent Esophageal Carcinoma, Recurrent Gastric Carcinoma, Recurrent Hepatocellular Carcinoma, Recurrent Lung Carcinoma, Recurrent Melanoma, Recurrent Ovarian Carcinoma, Recurrent Prostate Carcinoma, Recurrent Renal Cell Carcinoma, Recurrent Uterine Corpus Carcinoma, Resectable Hepatocellular Carcinoma, Sarcoma, Stage IA Breast Cancer, Stage IA Ovarian Cancer, Stage IA Uterine Corpus Cancer, Stage IB Breast Cancer, Stage IB Ovarian Cancer, Stage IB Uterine Corpus Cancer, Stage IC Ovarian Cancer, Stage II Uterine Corpus Cancer, Stage IIA Breast Cancer, Stage IIA Lung Carcinoma, Stage IIA Ovarian Cancer, Stage IIB Breast Cancer, Stage IIB Esophageal Cancer, Stage IIB Lung Carcinoma, Stage IIB Ovarian Cancer, Stage IIB Skin Melanoma, Stage IIC Ovarian Cancer, Stage IIC Skin Melanoma, Stage IIIA Breast Cancer, Stage IIIA Esophageal Cancer, Stage IIIA Lung Carcinoma, Stage IIIA Ovarian Cancer, Stage IIIA Skin Melanoma, Stage IIIA Uterine Corpus Cancer, Stage IIIB Breast Cancer, Stage IIIB Esophageal Cancer, Stage IIIB Ovarian Cancer, Stage IIIB Skin Melanoma, Stage IIIB Uterine Corpus Cancer, Stage IIIC Breast Cancer, Stage IIIC Esophageal Cancer, Stage IIIC Ovarian Cancer, Stage IIIC Skin Melanoma, Stage IIIC Uterine Corpus Cancer, Stage IV Bladder Urothelial Carcinoma, Stage IV Esophageal Cancer, Stage IV Ovarian Cancer, Stage IV Prostate Cancer, Stage IV Skin Melanoma, Stage IVA Uterine Corpus Cancer, Stage IVB Uterine Corpus Cancer
    View official trial listing →
  • Completed NCT NCT01523977

    Everolimus With Multiagent Re-Induction Chemotherapy in Pediatric Patients With ALL

    Not yet reported Dana-Farber Cancer Institute 22 participants Est. completion 2018-11 8 sites
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT01524783

    Everolimus Plus Best Supportive Care vs Placebo Plus Best Supportive Care in the Treatment of Patients With Advanced Neuroendocrine Tumors (GI or Lung Origin)

    Not yet reported Novartis Pharmaceuticals 302 participants Est. completion 2020-08-07 97 sites
    Other conditions: Advanced NET of GI Origin, Advanced NET of Lung Origin, Neuroendocrine Tumors
    View official trial listing →
  • Status unknown NCT NCT01525719

    Single Arm Study of RAD001 as Monotherapy in Treatment in Advanced Cholangiocarcinoma

    Not yet reported Ratchavithi Hospital 40 participants Est. completion 2014-06
    Other conditions: Cholangiocarcinoma
    View official trial listing →
  • Completed NCT NCT01526356

    Topical Rapamycin to Erase Angiofibromas in TSC

    Not yet reported The University of Texas Health Science Center, Houston 179 participants Est. completion 2014-08 10 sites
    Other conditions: Angiofibromas, Tuberous Sclerosis
    View official trial listing →
  • Completed NCT NCT01529138

    Study of Axitinib and Temsirolimus in Solid Tumors

    Not yet reported Emory University 13 participants Est. completion 2014-03 1 site Stand-alone
    Other conditions: Cancer
    View official trial listing →
  • Completed NCT NCT01529554

    Controlled Level EVERolimus in Acute Coronary Syndromes

    Not yet reported, Not yet reported University of Zurich 150 participants Est. completion 2021-11-29 8 sites
    Other conditions: Acute Coronary Syndromes
    View official trial listing →
  • Terminated NCT NCT01529593

    Temsirolimus in Combination With Metformin in Patients With Advanced Cancers

    Not yet reported M.D. Anderson Cancer Center 34 participants Est. completion 2025-03-14 1 site
    Other conditions: Advanced Cancers
    View official trial listing →
  • Terminated NCT NCT01534143

    High Dose Busulfan and Bortezomib in Treating Patients With High Risk Multiple Myeloma Undergoing Stem Cell Transplant

    Not yet reported Barbara Ann Karmanos Cancer Institute 1 participants Est. completion 2013-05 1 site Stand-alone
    Other conditions: Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT01535989

    Study of Inotuzumab Ozogamicin + Temsirolimus in Patients With Relapsed or Refractory CD22+ B-cell NHLymphoma

    Not yet reported Cristiana Sessa 25 participants Est. completion 2016-06 3 sites
    Other conditions: B-cell Lymphoma Refractory
    View official trial listing →
  • Completed NCT NCT01536054

    Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cavity Cancer

    Not yet reported Roswell Park Cancer Institute 7 participants Est. completion 2015-04-21 1 site Stand-alone
    Other conditions: Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Primary Peritoneal Cavity Cancer, Stage IIA Fallopian Tube Cancer, Stage IIA Ovarian Epithelial Cancer, Stage IIA Primary Peritoneal Cavity Cancer, Stage IIB Fallopian Tube Cancer, Stage IIB Ovarian Epithelial Cancer, Stage IIB Primary Peritoneal Cavity Cancer, Stage IIC Fallopian Tube Cancer, Stage IIC Ovarian Epithelial Cancer, Stage IIC Primary Peritoneal Cavity Cancer, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Epithelial Cancer, Stage IIIA Primary Peritoneal Cavity Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Epithelial Cancer, Stage IIIB Primary Peritoneal Cavity Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Epithelial Cancer, Stage IIIC Primary Peritoneal Cavity Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Epithelial Cancer, Stage IV Primary Peritoneal Cavity Cancer
    View official trial listing →
  • Completed NCT NCT01537107

    Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By Surgery

    Not yet reported Mayo Clinic 31 participants Est. completion 2018-06-27 3 sites Stand-alone
    Other conditions: Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage IV Pancreatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT01543373

    Optical Coherence Tomography Comparison of Neointimal Coverage Between CRE8 DES and BMS

    Not yet reported CID - Carbostent & Implantable Devices 38 participants Est. completion 2014-04 6 sites Stand-alone
    Other conditions: Stable Angina, Unstable Angina, NSTEMI
    View official trial listing →
  • Completed NCT NCT01544491

    Efficacy, Tolerability and Safety of Early Introduction of Everolimus, Reduced Calcineurin Inhibitors and Early Steroid Elimination Compared to Standard CNI, Mycophenolate Mofetil and Steroid Regimen in Paediatric Renal Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 106 participants Est. completion 2018-09-24 31 sites
    Other conditions: Prevention of Acute Rejection in Paediatric Recipients of a Renal Transplant
    View official trial listing →
  • Completed NCT NCT01545947

    Study Assessing Safety, Pharmacokinetics and Efficacy of CC-223 With Either Erlotinib or Oral Azacitidine in Advanced Non-Small Cell Lung Cancer

    Not yet reported Celgene 76 participants Est. completion 2014-12-11 9 sites
    Other conditions: Carcinoma, Non-Small-Cell Lung, Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT01548482

    Trebananib And Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

    Not yet reported National Cancer Institute (NCI) 21 participants Est. completion 2014-01 3 sites
    Other conditions: Adult Solid Neoplasm, Lung Carcinoid Tumor, Recurrent Digestive System Neuroendocrine Tumor G1, Recurrent Renal Cell Carcinoma, Recurrent Uterine Corpus Sarcoma, Stage III Renal Cell Cancer, Stage IIIB Uterine Sarcoma, Stage IIIC Uterine Sarcoma, Stage IV Renal Cell Cancer, Stage IVA Uterine Sarcoma, Stage IVB Uterine Sarcoma
    View official trial listing →
  • Completed NCT NCT01548807

    Phase 1 Trial of the Mammalian Target of Rapamycin (mTOR) Inhibitor Everolimus Plus Radiation Therapy (RT) for Salvage Treatment of Biochemical Recurrence in Prostate Cancer Patients Following Prostatectomy

    Not yet reported Abramson Cancer Center at Penn Medicine 19 participants Est. completion 2017-01-04 1 site
    Other conditions: Prostate Cancer Patients With Detectable PSA Following Prostatectomy
    View official trial listing →
  • Completed NCT NCT01551212

    Efficacy of Everolimus in Combination With Tacrolimus in Liver Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 339 participants Est. completion 2017-08-08 15 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Terminated NCT NCT01552434

    Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

    Not yet reported M.D. Anderson Cancer Center 154 participants Est. completion 2026-05-08 1 site
    Other conditions: Advanced Malignant Neoplasm, Castleman Disease, Digestive System Carcinoma, Erdheim-Chester Disease, Lip and Oral Cavity Carcinoma, Lymphangioleiomyomatosis, Malignant Endocrine Neoplasm, Malignant Female Reproductive System Neoplasm, Malignant Male Reproductive System Neoplasm, Malignant Neoplasm, Malignant Respiratory Tract Neoplasm, Malignant Thoracic Neoplasm, Malignant Urinary System Neoplasm, Mesothelial Neoplasm, Metastatic Malignant Neoplasm, Metastatic Urothelial Carcinoma, Neurofibromatosis Type 2, Recurrent Adult Soft Tissue Sarcoma, Recurrent Breast Carcinoma, Recurrent Childhood Soft Tissue Sarcoma, Recurrent Digestive System Carcinoma, Recurrent Female Reproductive System Carcinoma, Recurrent Male Reproductive System Carcinoma, Recurrent Malignant Neoplasm, Recurrent Pharyngeal Carcinoma, Recurrent Thyroid Gland Carcinoma, Refractory Malignant Neoplasm, Soft Tissue Neoplasm, Stage III Breast Cancer AJCC v7, Stage III Pharyngeal Cancer, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Stage IV Breast Cancer AJCC v6 and v7, Stage IV Pharyngeal Cancer, Stage IVA Pharyngeal Cancer, Stage IVB Pharyngeal Cancer, Stage IVC Pharyngeal Cancer, Thyroid Gland Neoplasm
    View official trial listing →
  • Completed NCT NCT01556126

    Clinical Performance of CRE8 Drug Eluting Stent in All Comer Population

    Not yet reported CID - Carbostent & Implantable Devices 1191 participants Est. completion 2018-12 23 sites Stand-alone
    Cardiovascular disease Other conditions: Stable Angina, Unstable Angina
    View official trial listing →
  • Terminated NCT NCT01561404

    Effect of the Inhibition of the Mammalian Target of Rapamycin on Metabolism and Exercise

    Not yet reported Josep M Cruzado 3 participants Est. completion 2013-12 1 site
    Other conditions: Disorder Related to Renal Transplantation, Exercise, Aerobic, Muscle Strength
    View official trial listing →
  • Completed NCT NCT01563354

    3-arm Trial to Evaluate Pasireotide LAR/Everolimus Alone/in Combination in Patients With Lung/Thymus NET - LUNA Trial

    Not yet reported Novartis Pharmaceuticals 124 participants Est. completion 2020-02-10 36 sites
    Other conditions: Neuroendocrine Carcinoma of the Lung and Thymus
    View official trial listing →
  • Completed NCT NCT01566279

    A Study to Identify a Biomarker Predictive for Response on Everolimus in Solid Tumors (CPCT-03)

    Not yet reported UMC Utrecht 73 participants Est. completion 2016-11 3 sites
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Completed NCT NCT01567475

    The Combination of Rad001 and Rituximab In Patients With Non-hodgkin's Lymphomas

    Not yet reported The Lymphoma Academic Research Organisation 21 participants Est. completion 2015-12 5 sites
    Other conditions: Non-Hodgkin's Lymphomas
    View official trial listing →
  • Completed NCT NCT01567488

    Phase II Study of Everolimus Combined With Octreotide LAR to Treat Advanced GI NET

    Not yet reported Grupo Espanol de Tumores Neuroendocrinos 43 participants Est. completion 2017-06-07 1 site
    Other conditions: Gastrointestinal Neoplasms
    View official trial listing →
  • Status unknown NCT NCT01567930

    Temsirolimus as Second-line Therapy in HCC

    Not yet reported University of Tennessee Cancer Institute 25 participants Est. completion 2013-03 1 site
    Other conditions: Unresectable or Metastatic Hepatocellular Carcinoma
    View official trial listing →
  • Terminated NCT NCT01582009

    Panobinostat and Everolimus in Treating Patients With Metastatic or Unresectable Renal Cell Cancer That Does Not Respond to Treatment With Sunitinib Malate or Sorafenib Tosylate

    Not yet reported, Not yet reported Roswell Park Cancer Institute 26 participants Est. completion 2015-12 2 sites
    Other conditions: Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Cancer, Stage III Renal Cell Cancer, Stage IV Renal Cell Cancer
    View official trial listing →
  • Terminated NCT NCT01582048

    Multicenter Study of Peritransplantation Immunosuppression for Mismatched Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

    Not yet reported Prof. Dr. med. Wolfgang Bethge 9 participants Est. completion 2016-08-17 4 sites
    Other conditions: Patients Receiving Mismatched Allogeneic HCT
    View official trial listing →
  • Completed NCT NCT01582191

    Vandetanib and Everolimus in Treating Patients With Advanced or Metastatic Cancer

    Not yet reported M.D. Anderson Cancer Center 123 participants Est. completion 2025-10-22 1 site
    Other conditions: Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm, Refractory Malignant Neoplasm
    View official trial listing →
  • Completed NCT NCT01590199

    Evaluate Safety and Tolerability of Pasireotide LAR in Combination With Everolimus in Advanced Metastatic NETs

    Not yet reported Novartis Pharmaceuticals 18 participants Est. completion 2018-09-11 3 sites
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Status unknown NCT NCT01592253

    Study to Evaluate Safety and Immunologic Biomarker of Rapamune in Patients With Stable Renal Transplant Recipient

    Not yet reported Seoul St. Mary's Hospital 50 participants Est. completion 2013-12 1 site
    Other conditions: Acute Rejection of Renal Transplant
    View official trial listing →
  • Completed NCT NCT01594268

    A Prospective, Open Label Study of CERtican in KIdney Transplantation

    Not yet reported Novartis Pharmaceuticals 54 participants Est. completion 2013-10 4 sites
    Other conditions: Kidney Transplant
    View official trial listing →
  • Completed NCT NCT01595009

    An Open-label, Multi-center, Expanded Access Study of Everolimus in Participants With Advanced Neuroendocrine Tumors (NETs) (Core Study) and an Extension Study to the Open-label, Multi-center, Expanded Access Study of Everolimus in Patients With Advanced NETs (E1)

    Not yet reported Novartis Pharmaceuticals 246 participants Est. completion 2016-08-09 11 sites
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Completed NCT NCT01595841

    Sirolimus Use in Angioplasty for Vascular Access Extension

    Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 17 participants Est. completion 2022-03 1 site Stand-alone
    Other conditions: End Stage Renal Disease, Venous Stenosis
    View official trial listing →
  • Completed NCT NCT01595984

    Comparison of Efficacy and Safety of Treatment With a Calcineurin Inhibitor (CNI)Versus a CNI-free Treatment in Renal Transplantation (CIME)

    Not yet reported Centre Hospitalier Universitaire, Amiens 88 participants Est. completion 2024-03-05 2 sites
    Other conditions: Kidney Failure
    View official trial listing →
  • Completed NCT NCT01596062

    Pharmacodynamics, Efficacy and Safety of Basiliximab 40 or 80 mg in Combination With Ciclosporine Microemulsion or Everolimus, in Adult Low Risk de Novo Renal Transplant Recipients (IDEALE Study)

    Not yet reported Novartis Pharmaceuticals 16 participants Est. completion 2013-03 3 sites
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT01596140

    Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced Cancer

    Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2020-06-01 1 site
    Other conditions: Advanced Cancer, Solid Tumor
    View official trial listing →
  • Completed NCT NCT01601821

    Open Label Comparative Study Of De Novo Renal Allograft Recipients Receiving CSA + MMF + Corticosteroids Versus CSA + Rapamune + Corticosteroids

    Not yet reported Pfizer 245 participants Est. completion 2008-03 4 sites
    Other conditions: Inflammation
    View official trial listing →
  • Status unknown NCT NCT01608412

    A Clinical Trial to Assess the Efficacy and Safety of the Conversion to Everolimus

    Not yet reported Hospital de Clinicas de Porto Alegre 120 participants Est. completion 2014-07 1 site
    Other conditions: Kidney Transplant Recipients
    View official trial listing →
  • Terminated NCT NCT01609673

    Study of Everolimus in de Novo Renal Transplant Recipients

    Not yet reported Helady Pinheiro, MD, PhD 1 participants Est. completion 2013-05 4 sites
    Other conditions: End Stage Renal Failure With Renal Transplant
    View official trial listing →
  • Completed NCT NCT01611116

    Study With Temsirolimus Added to Standard Chemotherapy for Patients Over 60 Years With Acute Myeloblastic Leukemia

    Not yet reported Goethe University 33 participants Est. completion 2017-04-26 5 sites
    Other conditions: Acute Myeloblastic Leukemia
    View official trial listing →
  • Completed NCT NCT01614197

    A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma

    Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 16 participants Est. completion 2020-09-04 32 sites
    Other conditions: Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Lymphoma, Peripheral T-cell Lymphoma
    View official trial listing →
  • Status unknown NCT NCT01614301

    Phase I and Consecutive Phase II, Two-arm, Randomized Multi-center Trial in Patients With Advanced Melanoma

    Not yet reported, Not yet reported University of Regensburg 136 participants Est. completion 2016-05 1 site
    Other conditions: Advanced Melanoma
    View official trial listing →
  • Completed NCT NCT01614795

    Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma

    Not yet reported National Cancer Institute (NCI) 46 participants Est. completion 2014-04-01 76 sites
    Obstructive sleep apnea Other conditions: Childhood Alveolar Soft Part Sarcoma, Childhood Epithelioid Sarcoma, Childhood Malignant Peripheral Nerve Sheath Tumor, Childhood Synovial Sarcoma, Recurrent Childhood Soft Tissue Sarcoma, Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
    View official trial listing →
  • Withdrawn NCT NCT01616186

    Everolimus/Sorafenib or Sunitinib in Patients With Metastatic Renal Cell Carcinoma (RCC)

    Not yet reported Andrea Harzstark Est. completion 2016-04
    Other conditions: Locally Metastatic Malignant Neoplasm
    View official trial listing →
  • Completed NCT NCT01620307

    Rapamune Improves Outcomes of Severe H1N1 Pneumonia

    Not yet reported Chang Gung Memorial Hospital 38 participants Est. completion 2011-12
    Other conditions: H1N1 Pneumonia, Hypoxemia
    View official trial listing →
  • Completed NCT NCT01624766

    Everolimus and Anakinra or Denosumab in Treating Participants With Relapsed or Refractory Advanced Cancers

    Not yet reported M.D. Anderson Cancer Center 57 participants Est. completion 2021-02-24 1 site
    Other conditions: Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm, Refractory Malignant Neoplasm
    View official trial listing →
  • Completed NCT NCT01624948

    Safety and Efficacy Study of Everolimus to Treat BK Virus Infection in Kidney Transplant Recipients

    Not yet reported University of California, San Francisco 40 participants Est. completion 2015-11 1 site
    Other conditions: BK Virus Infection
    View official trial listing →
  • Completed NCT NCT01625156

    Tivantinib and Temsirolimus in Treating Patients With Solid Tumors That is Metastatic or Cannot be Removed by Surgery

    Not yet reported National Cancer Institute (NCI) 11 participants Est. completion 2015-10 2 sites
    Other conditions: Adult Solid Neoplasm
    View official trial listing →
  • Completed NCT NCT01625351

    A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

    Not yet reported St. Jude Children's Research Hospital 23 participants Est. completion 2020-02-10 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Ewing Sarcoma, Gastrointestinal Tumor, Germ Cell Tumor, Hepatic Tumor, Lymphoma, Wilms Tumor, Rhabdoid Tumor, Clear Cell Carcinoma, Renal Cell Carcinoma, Melanoma, Neuroblastoma
    View official trial listing →
  • Completed NCT NCT01625377

    A National Multi-center Randomized, Open Label Study to Evaluate Efficacy and Safety of Everolimus With EC-MPS Compared to Standard Treatment Combination Tacrolimus and EC-MPS in de Novo Liver Transplant Recipients

    Not yet reported Novartis Pharmaceuticals 188 participants Est. completion 2015-03 14 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Completed NCT NCT01625520

    SOM230 Alone or in Combination With RAD001 in Patients With Medullary Thyroid Cancer

    Not yet reported Federico II University 19 participants 1 site
    Other conditions: Medullary Thyroid Cancer
    View official trial listing →
  • Completed NCT NCT01626170

    Studying Mechanisms of Radiation Therapy Resistance in Samples From Younger Patients With Rhabdomyosarcoma

    Children's Oncology Group 20 participants 1 site
    Obstructive sleep apnea
    View official trial listing →
  • Completed NCT NCT01626222

    4EVER - Efficacy, Safety, Health Economics, Translational Research of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer

    Not yet reported Novartis Pharmaceuticals 301 participants Est. completion 2013-11 84 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Terminated NCT NCT01627067

    Exemestane-RAD001-Metformin

    Not yet reported M.D. Anderson Cancer Center 23 participants Est. completion 2019-02-01 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT01628913

    Efficacy and Safety of BEZ235 Compared to Everolimus in Patients With Advanced Pancreatic Neuroendocrine Tumors

    Not yet reported Novartis Pharmaceuticals 62 participants Est. completion 2014-09 26 sites
    Other conditions: Pancreatic Neuroendocrine Tumors (pNET)
    View official trial listing →
  • Status unknown NCT NCT01631058

    Renal Transplantation in the Elderly - nEverOld Study

    Not yet reported University of Sao Paulo General Hospital 90 participants Est. completion 2019-06 2 sites
    Other conditions: Chronic Renal Failure (CRF), Graft Failure, Transplant; Failure, Kidney, Renal Transplant Rejection
    View official trial listing →
  • Completed NCT NCT01632605

    The Vienna RAP Pilot Study

    Not yet reported Medical University of Vienna 8 participants Est. completion 2012-04 1 site Stand-alone
    Other conditions: ADPKD
    View official trial listing →
  • Terminated NCT NCT01633060

    A Phase III Study of BKM120 With Fulvestrant in Patients With HR+,HER2-, AI Treated, Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORi

    Not yet reported Novartis Pharmaceuticals 432 participants Est. completion 2017-09-21 197 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT01634217

    Inducible Regulatory T Cells (iTregs) in Non-Myeloablative Sibling Donor Peripheral Blood Stem Cell Transplantation

    Not yet reported Masonic Cancer Center, University of Minnesota 16 participants Est. completion 2018-12-01 1 site Stand-alone
    Other conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Non-Hodgkin Lymphoma, Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Multiple Myeloma, Myelodysplastic Syndrome
    View official trial listing →
  • Terminated NCT NCT01636466

    The Everolimus-Transplant Exit Strategy Trial (E-TEST)

    Not yet reported Ashtar Chami 1 participants Est. completion 2014-05 1 site
    Other conditions: Kidney Failure, Chronic
    View official trial listing →
  • Completed NCT NCT01636908

    Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies.

    Not yet reported Amsterdam UMC, location VUmc 43 participants Est. completion 2019-12-01 1 site
    Other conditions: Cancer, Advanced Solid Tumors
    View official trial listing →
  • Completed NCT NCT01637012

    Prospective, Single-arm, Multicenter Study for Evaluation the Safety and Effectiveness of the ALEX Stent in a Real-world Setting of Percutaneous Coronary Interventions in Patients With Coronary Heart Disease

    Not yet reported Balton Sp.zo.o. 60 participants Est. completion 2013-09 5 sites
    Cardiovascular disease Other conditions: Stable Angina, Unstable Angina
    View official trial listing →
  • Terminated NCT NCT01637090

    Everolimus in Treating Cutaneous T-cell Lymphoma

    Not yet reported Adam Lerner 3 participants Est. completion 2015-05 1 site
    Other conditions: Cutaneous T-Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT01637194

    Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck Cancer

    Not yet reported Fox Chase Cancer Center 12 participants Est. completion 2011-07 1 site
    Other conditions: Recurrent Adenoid Cystic Carcinoma of the Oral Cavity, Recurrent Basal Cell Carcinoma of the Lip, Recurrent Colon Cancer, Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity, Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity, Recurrent Lymphoepithelioma of the Nasopharynx, Recurrent Lymphoepithelioma of the Oropharynx, Recurrent Metastatic Squamous Neck Cancer With Occult Primary, Recurrent Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity, Recurrent Mucoepidermoid Carcinoma of the Oral Cavity, Recurrent Salivary Gland Cancer, Recurrent Squamous Cell Carcinoma of the Hypopharynx, Recurrent Squamous Cell Carcinoma of the Larynx, Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity, Recurrent Squamous Cell Carcinoma of the Nasopharynx, Recurrent Squamous Cell Carcinoma of the Oropharynx, Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Recurrent Verrucous Carcinoma of the Larynx, Recurrent Verrucous Carcinoma of the Oral Cavity, Stage IV Adenoid Cystic Carcinoma of the Oral Cavity, Stage IV Basal Cell Carcinoma of the Lip, Stage IV Lymphoepithelioma of the Nasopharynx, Stage IV Lymphoepithelioma of the Oropharynx, Stage IV Mucoepidermoid Carcinoma of the Oral Cavity, Stage IV Squamous Cell Carcinoma of the Hypopharynx, Stage IV Squamous Cell Carcinoma of the Larynx, Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity, Stage IV Squamous Cell Carcinoma of the Nasopharynx, Stage IV Squamous Cell Carcinoma of the Oropharynx, Stage IV Verrucous Carcinoma of the Larynx, Stage IV Verrucous Carcinoma of the Oral Cavity, Stage IVA Colon Cancer, Stage IVA Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity, Stage IVA Inverted Papilloma of the Paranasal Sinus and Nasal Cavity, Stage IVA Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity, Stage IVA Salivary Gland Cancer, Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Stage IVB Colon Cancer, Stage IVB Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity, Stage IVB Inverted Papilloma of the Paranasal Sinus and Nasal Cavity, Stage IVB Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity, Stage IVB Salivary Gland Cancer, Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Stage IVC Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity, Stage IVC Inverted Papilloma of the Paranasal Sinus and Nasal Cavity, Stage IVC Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity, Stage IVC Salivary Gland Cancer, Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity, Tongue Cancer
    View official trial listing →
  • Completed NCT NCT01640743

    Effect of Different Therapeutic Strategies on Regulatory T Cells in Kidney Transplantation

    Not yet reported Fondazione IRCCS Policlinico San Matteo di Pavia 58 participants Est. completion 2014-04 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT01642186

    Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC)

    Not yet reported Memorial Sloan Kettering Cancer Center 28 participants Est. completion 2021-07-16 6 sites
    Other conditions: Fibrolamellar Carcinoma, Fibrolamellar Liver Cancer
    View official trial listing →
  • Terminated NCT NCT01642732

    Study of Everolimus Added to Combined Hormonal and Radiation Therapy for High Risk Prostate Cancer

    Not yet reported University of Michigan Rogel Cancer Center 1 participants Est. completion 2014-08 2 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01646021

    Study of Ibrutinib (a Bruton's Tyrosine Kinase Inhibitor), Versus Temsirolimus in Patients With Relapsed or Refractory Mantle Cell Lymphoma Who Have Received at Least One Prior Therapy

    Not yet reported Janssen Research & Development, LLC 280 participants Est. completion 2016-12-15 92 sites
    Other conditions: Mantle Cell Lymphoma
    View official trial listing →
  • Terminated NCT NCT01648465

    Study of Everolimus Treatment in Newly-diagnosed Patients With Advanced Gastrointestinal Neuroendocrine Tumors

    Not yet reported Hellenic Cooperative Oncology Group 25 participants Est. completion 2019-08-06 12 sites
    Other conditions: Gastrointestinal Tumors, Pancreatic Tumors, Gastrointestinal Neuroendocrine Tumors, Pancreatic Neuroendocrine Tumors
    View official trial listing →
  • Completed NCT NCT01649609

    Using mTOR Inhibitors in the Prevention of BK Nephropathy

    Not yet reported Columbia University 40 participants Est. completion 2016-12 2 sites
    Other conditions: BK Viremia, BK Nephropathy
    View official trial listing →
  • Completed NCT NCT01649960

    Exercise and Low-Dose Rapamycin in Older Adults With CAD:Cardiac Rehabilitation And Rapamycin in Elderly (CARE) Trial

    Not yet reported Mayo Clinic 13 participants Est. completion 2015-12 1 site
    Other conditions: Aging, CAD
    View official trial listing →
  • Completed NCT NCT01650545

    Aerosol Liposomal Cyclosporine for Chronic Rejection in Lung Transplant Recipients

    Not yet reported, Not yet reported University of Maryland, Baltimore 21 participants Est. completion 2019-11 1 site
    Other conditions: Disorder Related to Lung Transplantation, Bronchiolitis Obliterans, Decreased Immunologic Activity, Chronic Rejection of Lung Transplant
    View official trial listing →
  • Completed NCT NCT01651390

    Clinical Performance of the Pantera Lux Balloon Versus the Orsiro Stent in Patients With In-stent Restenosis.

    Not yet reported Biotronik AG 231 participants Est. completion 2016-07 14 sites
    Cardiovascular disease Other conditions: Coronary Restenosis
    View official trial listing →
  • Completed NCT NCT01653041

    Certican (Everolimus) for Recipients of Kidney From HLA-identical Living Donors

    Not yet reported Hospital do Rim e Hipertensão 47 participants Est. completion 2015-04 1 site
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Status unknown NCT NCT01653067

    STORM: Temsirolimus, Rituximab and DHAP for Relapsed and Refractory Diffuse Large B-cell Lymphoma

    Not yet reported Mathias Witzens-Harig 88 participants Est. completion 2018-07 9 sites
    Other conditions: Diffuse Large B-Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT01653847

    Study in Recipients of Renal Transplant Allograft to Evaluate the Impact of Two Immunosuppressive Regimens

    Not yet reported Northwestern University 88 participants Est. completion 2020-05 1 site
    Other conditions: End Stage Renal Failure With Renal Transplant
    View official trial listing →
  • Terminated NCT NCT01658007

    Pilot Study Of Sirolimus Plus Multiagent Chemotherapy For Relapsed/Refractory Acute Lymphoblastic Leukemia/Lymphoma

    Not yet reported Children's Hospital Medical Center, Cincinnati 3 participants Est. completion 2017-01 1 site Stand-alone
    Other conditions: Relapsed Lymphoblastic Leukemia, Recurrent Adult Lymphoblastic Lymphoma, Refractory Acute Lymphoblastic Leukemia, Refractory Lymphoblastic Lymphoma
    View official trial listing →
  • Withdrawn NCT NCT01658176

    Study Of PF-04691502 (PI3K/mTOR Inhibitor) In Combination With Exemestane Compared With Exemestane Alone In Patients With Advanced Breast Cancer

    Not yet reported Pfizer Est. completion 2015-04
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Completed NCT NCT01658436

    BEZ235 Phase II Trial in Patients With Advanced Pancreatic Neuroendocrine Tumors (pNET) After Failure of mTOR Inhibitor Therapy.

    Not yet reported Novartis Pharmaceuticals 31 participants Est. completion 2015-07 17 sites
    Other conditions: Pancreatic Neuroendocrine Tumors (pNET)
    View official trial listing →
  • Completed NCT NCT01661283

    SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors

    Not yet reported Sarcoma Alliance for Research through Collaboration 25 participants Est. completion 2017-12 12 sites
    Other conditions: Malignant Peripheral Nerve Sheath Tumors, MPNST, Sarcoma
    View official trial listing →
  • Status unknown NCT NCT01663805

    Effects of the Use of "de Novo" Everolimus in Renal Tranplant Population

    Not yet reported MARIO ABBUD FILHO 80 participants Est. completion 2015-06 3 sites
    Other conditions: Delayed Function of Renal Transplant
    View official trial listing →
  • Completed NCT NCT01665768

    Maintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in Lymphoma

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 56 participants Est. completion 2020-08 1 site
    Other conditions: CD20+, B-cell Lymphomas, Mantle Cell Lymphoma, Non-Mantle Cell Low Grade B Cell Lymphomas (SLL/CLL), Transformed Lymphoma/DLBCL/PMBCL, Hodgkin's Disease, Gray Zone Lymphoma
    View official trial listing →
  • Completed NCT NCT01668784

    Study of Nivolumab (BMS-936558) vs. Everolimus in Pre-Treated Advanced or Metastatic Clear-cell Renal Cell Carcinoma (CheckMate 025)

    Not yet reported Bristol-Myers Squibb 821 participants Est. completion 2021-07-19 168 sites
    Other conditions: Advanced or Metastatic (Medically or Surgically Unresectable) Clear-cell Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01670175

    Sirolimus With Cyclophosphamide and Topotecan for Pediatric/Adolescent Relapsed and Refractory Solid Tumors

    Not yet reported University of California, San Francisco 21 participants Est. completion 2016-09 1 site Stand-alone
    Other conditions: Malignant Solid Tumor, Childhood Solid Tumor
    View official trial listing →
  • Completed NCT NCT01672151

    Efficacy of Rapamycin Therapy With Chronic Immune Thrombocytopenia

    First Affiliated Hospital of Suzhou Medical College 35 participants Est. completion 2012-08 1 site
    Other conditions: Immune Thrombocytopenic Purpura
    View official trial listing →
  • Active, not recruiting NCT NCT01674140

    S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer

    Not yet reported SWOG Cancer Research Network 1939 participants Est. completion 2030-01 1459 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01674803

    Comparison of BIOdegradable Polymer and DuRablE Polymer Drug-eluting Stents in an All COmeRs PopulaTion (BIO-RESORT)

    Not yet reported Foundation of Cardiovascular Research and Education Enschede 3514 participants Est. completion 2020-08-25 1 site
    Cardiovascular disease Other conditions: Acute Coronary Syndrome, Angina Pectoris, Angina, Unstable, Coronary Stenosis, Coronary Restenosis
    View official trial listing →
  • Terminated NCT NCT01675947

    Intravitreal Injections of Sirolimus in the Treatment of Geographic Atrophy

    Not yet reported National Eye Institute (NEI) 52 participants Est. completion 2016-02 13 sites Stand-alone
    Other conditions: Geographic Atrophy
    View official trial listing →
  • Terminated NCT NCT01677390

    A Phase 1b Study of SGN-75 in Combination With Everolimus in Patients With Renal Cell Carcinoma

    Not yet reported Seagen Inc. 4 participants Est. completion 2013-12 8 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01678664

    Everolimus After (Chemo)Embolization for Liver Metastases From Digestive Endocrine Tumors

    Not yet reported Federation Francophone de Cancerologie Digestive 74 participants Est. completion 2019-04 18 sites
    Other conditions: Neuroendocrine Tumors, Hepatic Metastases, Metastases
    View official trial listing →
  • Completed NCT NCT01678937

    Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents

    Northwestern University 31 participants Est. completion 2008-09 1 site
    Other conditions: Liver Transplant Rejection, Immunosuppression
    View official trial listing →
  • Status unknown NCT NCT01680250

    Sirolimus for Massive Polycystic Liver

    Not yet reported, Not yet reported Seoul National University Hospital 44 participants Est. completion 2015-08 1 site Stand-alone
    Other conditions: Polycystic Kidney Diseases
    View official trial listing →
  • Completed NCT NCT01680861

    Tacrolimus/Everolimus Versus Tacrolimus/Enteric-Coated Mycophenolate Sodium

    Not yet reported Gaetano Ciancio 32 participants Est. completion 2014-12 1 site
    Other conditions: Transplant; Failure, Kidney
    View official trial listing →
  • Completed NCT NCT01680952

    Study to Evaluate the Safety and Efficacy of Extended Release Tacrolimus (Advagraf®) + Sirolimus (Rapamune®), Versus Extended Release Tacrolimus (Advagraf®) + Mycophenolate Mofetil in Kidney Transplant Patients

    Not yet reported Yonsei University 158 participants Est. completion 2016-01 7 sites Stand-alone
    Other conditions: Kidney Transplant Patients
    View official trial listing →
  • Status unknown NCT NCT01681381

    Evaluate Safety And Effectiveness Of The Tivoli® DES and The Firebird2® DES For Treatment Coronary Revascularization

    Not yet reported Essen Technology (Beijing) Co., Ltd. 2790 participants Est. completion 2018-09 1 site
    Other conditions: Ischemic Heart Disease, Myocardial Ischemia, Coronary Artery Lesions,Primary, Coronary Disease, Acute Coronary Syndrome, Furcation Lesion of Coronary Artery
    View official trial listing →
  • Completed NCT NCT01684449

    Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma

    Not yet reported, Not yet reported Grupo Espanol de Investigacion en Sarcomas 28 participants Est. completion 2013-12 9 sites
    Other conditions: Advanced Soft Tissue Sarcoma
    View official trial listing →
  • Completed NCT NCT01684982

    Everolimus Stent in Myocardial Infarction

    Not yet reported San Giuseppe Moscati Hospital 500 participants Est. completion 2012-06 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01687075

    CRE8 in All Comers Patients

    Not yet reported Tel-Aviv Sourasky Medical Center 215 participants Est. completion 2014-08 1 site Stand-alone
    Other conditions: Consecutive Subjects Who Are Suitable for a Coronary, Angioplasty of de Novo Lesion(s) in Native Coronary, Arteries Should be Screened for Eligibility., A Total Number of 200 Patients Fulfilling the Selection, Criteria and Willing to Sign the Informed Consent Should, be Enrolled in the Trial.
    View official trial listing →
  • Completed NCT NCT01687179

    Safety Study of Sirolimus and Hydroxychloroquine in Women With Lymphangioleiomyomatosis

    Not yet reported Brigham and Women's Hospital 14 participants Est. completion 2015-08 1 site Stand-alone
    Other conditions: Lymphangioleiomyomatosis
    View official trial listing →
  • Completed NCT NCT01687673

    Phase II Combination of Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma

    Not yet reported University of California, San Francisco 29 participants Est. completion 2020-01-09 2 sites
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT01689987

    Hydroxychloroquine, Cyclophosphamide, Dexamethasone, and Sirolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma

    Not yet reported OHSU Knight Cancer Institute 18 participants 1 site Stand-alone
    Other conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
    View official trial listing →
  • Completed NCT NCT01698918

    Open-label, Phase II, Study of Everolimus Plus Letrozole in Postmenopausal Women With ER+, HER2- Metastatic or Locally Advanced Breast Cancer

    Not yet reported Novartis Pharmaceuticals 202 participants Est. completion 2021-01-13 52 sites
    Other conditions: Hormone Receptor Positive Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT01699360

    The Biomarker for Immunosuppressive Agents Metabolism in Chinese Renal Transplant Recipients

    Not yet reported Central South University 600 participants Est. completion 2013-12 1 site Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT01700400

    Study of Everolimus, Pemetrexed, Carboplatin, and Bevacizumab to Treat Stage IV Lung Cancer

    Not yet reported Cancer Research and Biostatistics Clinical Trials Consortium 13 participants Est. completion 2014-10 4 sites
    Other conditions: Non Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT01706471

    Safety and Efficacy of the Early Introduction of Everolimus (Certican®) With Low Dose of Cyclosporine in de Novo Kidney Recipients After 1 Month of Transplantation

    Not yet reported Yonsei University 60 participants Est. completion 2013-04 1 site
    Other conditions: Planned Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT01707849

    The Impact of Everolimus Based Immunosuppression in the Evolution of Hepatitis C Fibrosis After Liver Transplantation

    Not yet reported Hospital Vall d'Hebron 18 participants Est. completion 2016-08 1 site
    Other conditions: Hepatitis C Recurrence After Liver Transplant
    View official trial listing →
  • Terminated NCT NCT01709136

    Pharmacokinetics of Sirolimus and Tacrolimus in Liver Transplant Recipients With Tacrolimus Toxicity

    Not yet reported, Not yet reported University of Pittsburgh 3 participants Est. completion 2010-01 Stand-alone
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT01712828

    Effect of P-glycoprotein Inhibition on Lenalidomide Pharmacokinetics in Healthy Males

    Not yet reported Celgene 31 participants Est. completion 2013-01-01 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01713400

    Tacrolimus, Sirolimus and Ustekinumab vs. Tacrolimus and Sirolimus for the Prevention of Acute Graft-Versus-Host Disease

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 54 participants Est. completion 2018-06-14 1 site Stand-alone
    Other conditions: Graft vs. Host Disease
    View official trial listing →
  • Completed NCT NCT01713946

    A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures

    Not yet reported Novartis Pharmaceuticals 366 participants Est. completion 2017-10-25 104 sites
    Other conditions: Tuberous Sclerosis Complex-associated Refractory Seizures
    View official trial listing →
  • Completed NCT NCT01714765

    Dose Escalation Study Investigating Everolimus and Dovitinib in Metastatic Clear Cell Renal Cancer

    Not yet reported Queen Mary University of London 17 participants Est. completion 2012-10 1 site
    Other conditions: Metastatic Clear Cell Renal Cancer
    View official trial listing →
  • Completed NCT NCT01715935

    Biomarkers Before and After Nephrectomy of Locally Advanced or Metastatic Renal Cell Carcinoma Treated With Everolimus

    Not yet reported Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie 25 participants Est. completion 2016-04 10 sites
    Other conditions: Clear-cell Renal Carcinoma, Clear-cell Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT01730209

    Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex

    Not yet reported, Not yet reported Erasmus Medical Center 60 participants Est. completion 2016-11 1 site
    Other conditions: Tuberous Sclerosis Complex, TSC Related Cognitive Disability, TSC Related Autism, TSC Related Learning Problems
    View official trial listing →
  • Completed NCT NCT01731158

    Sequential Therapy in Metastatic Renal Cell Carinoma

    Not yet reported Central European Society for Anticancer Drug Research 22 participants Est. completion 2016-09 13 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01734512

    PNOC 001: Phase II Study of Everolimus for Recurrent or Progressive Low-grade Gliomas in Children

    Not yet reported University of California, San Francisco 65 participants Est. completion 2024-07-31 18 sites
    Other conditions: Pediatric Recurrent Progressive Low-grade Gliomas, Pediatric Progressive Low-grade Gliomas
    View official trial listing →
  • Completed NCT NCT01737502

    Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancer

    Not yet reported, Not yet reported Mayo Clinic 29 participants Est. completion 2023-04-24 2 sites Stand-alone
    Other conditions: Extensive Stage Small Cell Lung Carcinoma, Lung Adenocarcinoma, Recurrent Non-Small Cell Lung Carcinoma, Recurrent Small Cell Lung Carcinoma, Squamous Cell Lung Carcinoma, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung Cancer, Stage IV Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT01743560

    An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Treated With Everolimus (RAD001) With Exemestane, With Exploratory Epigenetic Marker Analysis

    Not yet reported Novartis Pharmaceuticals 52 participants Est. completion 2016-08-15 11 sites
    Other conditions: Oestrogen Receptor Positive Advanced Breast Cancer
    View official trial listing →
  • Completed NCT NCT01754389

    Standard of Care vs. Bortezomib in Graft-Versus Host Disease After Hematopoietic Stem Cell Transplant

    Not yet reported Dana-Farber Cancer Institute 138 participants Est. completion 2016-11 4 sites Stand-alone
    Other conditions: Graft Versus Host Disease
    View official trial listing →
  • Completed NCT NCT01756118

    A Phase I, Dose-finding Study of BEZ235 in Adult Patients With Relapsed or Refractory Acute Leukemia

    Not yet reported Goethe University 24 participants Est. completion 2020-02-07 1 site
    Other conditions: Acute Lymphoblastic Leukemia, Leukemia, Myelocytic, Acute, Chronic Myelogenous Leukemia With Crisis of Blast Cells
    View official trial listing →
  • Completed NCT NCT01756807

    EGO-COMBO Angiographic Extension Study

    Not yet reported Prof. Stephen Lee 41 participants Est. completion 2013-06 1 site Stand-alone
    Other conditions: Coronary Disease
    View official trial listing →
  • Status unknown NCT NCT01758107

    Study of Cyclosporine Withdrawal Regimen in Thai Renal Transplant Recipients

    Not yet reported Chulalongkorn University 30 participants Est. completion 2015-10 1 site Stand-alone
    Other conditions: Renal Transplant
    View official trial listing →
  • Terminated NCT NCT01758575

    Clinical Evaluation of the Underlying Mechanisms of Targeted Therapy Related Toxicities

    Amsterdam UMC, location VUmc 8 participants Est. completion 2017-04 1 site
    Other conditions: Advanced or Metastatic Solid Malignancy
    View official trial listing →
  • Suspended NCT NCT01762410

    Clinical Study of Oral PI3K/mTOR Inhibitor in Patients With Advanced Refractory Solid Tumors

    Not yet reported Piramal Enterprises Limited 60 participants Est. completion 2016-03 4 sites
    Other conditions: Advanced Refractory Solid Tumors
    View official trial listing →
  • Terminated NCT NCT01764607

    Sirolimus in Kidney Transplant Patients With Squamous Cell Skin Carcinoma

    Not yet reported University of Florida 1 participants Est. completion 2014-06 1 site Stand-alone
    Other conditions: Squamous Cell Skin Carcinoma
    View official trial listing →
  • Completed NCT NCT01767194

    Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

    Not yet reported National Cancer Institute (NCI) 73 participants Est. completion 2022-09-30 157 sites
    Other conditions: Ganglioneuroblastoma, Recurrent Neuroblastoma
    View official trial listing →
  • Terminated NCT NCT01773460

    Everolimus Beyond Progress for Patients Who Had Progress Under Everolimus and Exemestane

    Not yet reported GBG Forschungs GmbH 3 participants Est. completion 2014-07 1 site
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT01777204

    Gastrointestinal Transit and Motility in Renal Transplant Recipients

    Universidade Estadual de Ciências da Saúde de Alagoas 20 participants Est. completion 2013-01 1 site
    Other conditions: Change of Transit or Circulation, Effects of Immunosuppressant Therapy
    View official trial listing →
  • Completed NCT NCT01780948

    Pharmacokinetic of Everolimus and Atorvastatin Co-administration

    Not yet reported Chulalongkorn University 18 participants Est. completion 2013-01 1 site
    Other conditions: Difference of 12-hour AUC
    View official trial listing →
  • Withdrawn NCT NCT01781442

    A Post Marketing Surveillance As Required By Philippine Food And Drug Administration

    Pfizer Est. completion 2015-06
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01783444

    A Phase II Study of Everolimus in Combination With Exemestane Versus Everolimus Alone Versus Capecitabine in Advance Breast Cancer.

    Not yet reported Novartis Pharmaceuticals 309 participants Est. completion 2018-07-30 83 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01783756

    Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS Metastasis

    Not yet reported, Not yet reported Jonsson Comprehensive Cancer Center 9 participants Est. completion 2019-05-10 1 site
    Other conditions: Central Nervous System Metastases, HER2-positive Breast Cancer, Male Breast Cancer, Recurrent Breast Cancer, Stage IV Breast Cancer
    View official trial listing →
  • Terminated NCT NCT01784861

    VEGFR/PDGFR Dual Kinase Inhibitor X-82 and Everolimus for Treating Patients With Pancreatic Neuroendocrine Tumors

    Not yet reported, Not yet reported Washington University School of Medicine 23 participants Est. completion 2020-08-19 2 sites
    Other conditions: Adenocarcinoma, Pancreatic Neoplasms
    View official trial listing →
  • Terminated NCT NCT01784978

    Efficacy Study of Sunitinib and Everolimus (Rotational vs Sequential Arm) in Pats. With m Clear Cell Renal Cancer

    Not yet reported Associació per a la Recerca Oncologica, Spain 41 participants Est. completion 2017-05-08 10 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01788150

    Safety and Efficacy Study of the Svelte Drug-Eluting Coronary Stent Delivery System

    Not yet reported Svelte Medical Systems, Inc. 159 participants Est. completion 2019-05-31 18 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01789281

    Everolimus Roll-over Protocol for Patients Who Have Completed a Previous Novartis-sponsored Everolimus Study.

    Not yet reported Novartis Pharmaceuticals 34 participants Est. completion 2020-08-28 24 sites
    Other conditions: Neoplasms
    View official trial listing →
  • Completed NCT NCT01791088

    Sirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery

    Not yet reported University of Chicago 56 participants Est. completion 2018-08-17 1 site Stand-alone
    Other conditions: Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific
    View official trial listing →
  • Terminated NCT NCT01793636

    A Study Comparing AZD2014 vs Everolimus in Patients With Metastatic Renal Cancer

    Not yet reported Queen Mary University of London 49 participants Est. completion 2015-11 9 sites
    Other conditions: Metastatic Clear Cell Renal Carcinoma
    View official trial listing →
  • Completed NCT NCT01797120

    Study of Fulvestrant +/- Everolimus in Post-Menopausal, Hormone-Receptor + Metastatic Breast Ca Resistant to AI

    Not yet reported PrECOG, LLC. 131 participants Est. completion 2017-09-12 25 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Terminated NCT NCT01797315

    Prevention of Skin Cancer in High Risk Patients After Conversion to a Sirolimus-based Immunosuppressive Protocol

    Not yet reported University Hospital of Berlin 40 participants Est. completion 2013-06
    Other conditions: Renal Transplant Patients at High-risk for Skin Cancer
    View official trial listing →
  • Completed NCT NCT01797523

    A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma

    Not yet reported M.D. Anderson Cancer Center 62 participants Est. completion 2026-02-04 6 sites
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT01798446

    A Phase II Study of Axitinib in Metastatic Non-clear Cell Renal Cell Carcinoma Patients Previously Treated With Temsirolimus

    Not yet reported Seoul National University Hospital 41 participants Est. completion 2016-12 1 site
    Other conditions: Renal Cell Carcinoma, Nonclear Cell, Temsirolimus Resistance
    View official trial listing →
  • Completed NCT NCT01801137

    The Efficacy of RAD 001 as Second Line Therapy in Patients With Transitional Cell Carcinoma TCC of the Urothelium

    Not yet reported Hopital Foch 54 participants Est. completion 2014-10 1 site
    Other conditions: Urothelial Cancer
    View official trial listing →
  • Completed NCT NCT01802268

    Planned Conversion From TAC to SRL-based Regimen in de Novo Kidney Transplant Recipients

    Not yet reported Helio Tedesco Silva Junior 320 participants Est. completion 2012-10 6 sites
    Other conditions: Kidney Transplant
    View official trial listing →
  • Completed NCT NCT01804374

    Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable Osteosarcoma

    Not yet reported Italian Sarcoma Group 38 participants Est. completion 2014-12 1 site
    Obstructive sleep apnea
    View official trial listing →
  • Active, not recruiting NCT NCT01805271

    Safety Study of Adding Everolimus to Adjuvant Hormone Therapy in Women With High Risk of Relapse, ER+ and HER2- Primary Breast Cancer, Free of Disease After Receiving at Least One Year of Adjuvant Hormone Therapy

    Not yet reported UNICANCER 1278 participants Est. completion 2030-06 2 sites
    Other conditions: Primary Non-metastatic Breast Cancer, Who Remain Disease-free
    View official trial listing →
  • Withdrawn NCT NCT01807767

    Myfortic in High MELD Liver Transplantation

    Not yet reported Medical College of Wisconsin Est. completion 2015-08 1 site
    Other conditions: High Model for End-Stage Liver Disease (MELD) Score
    View official trial listing →
  • Completed NCT NCT01809860

    A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy Subjects

    Not yet reported Astellas Pharma Global Development, Inc. 22 participants Est. completion 2012-01 1 site Stand-alone
    Other conditions: Healthy Subjects, Pharmacokinetics of Isavuconazole, Pharmacokinetics of Sirolimus
    View official trial listing →
  • Completed NCT NCT01811667

    Efficacy and Safety of the Mammalian Target of Rapamycin (mTor Rapamycin) Inhibitor in Vascular Malformations

    Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 19 participants Est. completion 2016-01 1 site Stand-alone
    Other conditions: Cardiovascular Abnormalities
    View official trial listing →
  • Terminated NCT NCT01814059

    Sirolimus for Eosinophil-Associated Gastrointestinal Disorders

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 4 participants Est. completion 2015-05-12 1 site
    Other conditions: Eosinophilic Gastroenteritis, Eosinophilic Esophagitis
    View official trial listing →
  • Completed NCT NCT01817504

    Systematic Transplantectomy Versus Conventional Care After Kidney Graft Failure

    Not yet reported Hospices Civils de Lyon 56 participants Est. completion 2021-11 9 sites
    Other conditions: Renal Transplantation
    View official trial listing →
  • Completed NCT NCT01822015

    Sirolimus, Idarubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 55 participants Est. completion 2019-12-12 1 site Stand-alone
    Other conditions: Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Erythroleukemia (M6a), Adult Pure Erythroid Leukemia (M6b), Untreated Adult Acute Myeloid Leukemia
    View official trial listing →
  • Completed NCT NCT01827267

    Neratinib With and Without Temsirolimus for Patients With HER2 Activating Mutations in Non-Small Cell Lung Cancer

    Not yet reported Puma Biotechnology, Inc. 62 participants Est. completion 2017-10-06 21 sites
    Other conditions: HER2-mutant Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT01827384

    MPACT Study to Compare Effects of Targeted Drugs on Tumor Gene Variations

    Not yet reported National Cancer Institute (NCI) 208 participants Est. completion 2021-10-08 8 sites
    Other conditions: Advanced Malignant Solid Neoplasm
    View official trial listing →
  • Completed NCT NCT01827618

    Neoadjuvant Rapamycin in Patients Undergoing Radical Cystectomy

    Not yet reported The University of Texas Health Science Center at San Antonio 29 participants Est. completion 2014-04 1 site
    Other conditions: Invasive Bladder Cancer Stage II
    View official trial listing →
  • Completed NCT NCT01827943

    Phase II Evaluating Efficacy of Temsirolimus in 2 Line Therapy for Patients With Advanced Bladder Cancer

    Not yet reported Institut Bergonié 54 participants Est. completion 2016-12 9 sites
    Other conditions: Relapsed Bladder Cancer
    View official trial listing →
  • Completed NCT NCT01830153

    RAD001 in Advanced Sarcoma

    Not yet reported Asan Medical Center 41 participants 8 sites
    Other conditions: Soft Tissue Sarcomas, Bone Sarcomas
    View official trial listing →
  • Terminated NCT NCT01842594

    A Phase II Trial of Combined Hydroxychloroquine and Sirolimus in Soft Tissue Sarcoma

    Not yet reported Shin Kong Wu Ho-Su Memorial Hospital 13 participants Est. completion 2015-01 1 site Stand-alone
    Other conditions: Sarcoma
    View official trial listing →
  • Completed NCT NCT01843348

    12 Month Athena Study: Everolimus vs. Standard Regimen in de Novo Kidney Transplant Patients

    Not yet reported Novartis Pharmaceuticals 612 participants Est. completion 2016-03-23 27 sites
    Other conditions: Kidney Transplantation, Renal Transplantation
    View official trial listing →
  • Withdrawn NCT NCT01843998

    Therapeutic Efficacy of Topical Sirolimus in Early Stage Cutaneous T-cell Lymphoma (CTCL)

    Not yet reported Stefan Schieke MD Est. completion 2015-12 1 site Stand-alone
    Other conditions: Cutaneous T-cell Lymphoma (CTCL)
    View official trial listing →
  • Completed NCT NCT01845311

    ReZolve2 Clinical Investigation

    Not yet reported REVA Medical, Inc. 89 participants Est. completion 2019-01 3 sites
    Cardiovascular disease Other conditions: Coronary Artery Stenosis
    View official trial listing →
  • Status unknown NCT NCT01850108

    Non-Myeloablative Conditioning and Bone Marrow Transplantation

    Not yet reported Vanderbilt-Ingram Cancer Center 26 participants Est. completion 2024-12-31 3 sites Stand-alone
    Other conditions: Sickle Cell Disease, Hemoglobinopathies
    View official trial listing →
  • Withdrawn NCT NCT01851408

    Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma

    Not yet reported National Cancer Institute (NCI) Est. completion 2012-02
    Other conditions: Melanoma, Recurrent Melanoma, Stage III Melanoma, Stage IV Melanoma
    View official trial listing →
  • Completed NCT NCT01853423

    Tuberous Sclerosis Complex: Facial Angiofibroma Skin Cream

    Not yet reported Le Bonheur Children's Hospital 11 participants Est. completion 2016-07 1 site
    Other conditions: Facial Angiofibroma
    View official trial listing →
  • Completed NCT NCT01854606

    Safety and Efficacy of AEB071 and EVEROLIMUS in Patients With CD79-mutant or ABC Subtype Diffuse Large B-Cell Lymphoma

    Not yet reported Novartis Pharmaceuticals 31 participants Est. completion 2016-06-01 15 sites
    Other conditions: CD79 Mutant or ABC-subtype Diffuse Large B-Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT01856088

    DESTINY TRIAL (Inspiron x Biomatrix)

    Not yet reported Scitech Produtos Medicos SA 170 participants Est. completion 2019-03-21 10 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT01856101

    Study of BEZ235 as Monotherapy in Patients With Transitional Cell Carcinoma After Failure of Platinum Based Chemotherapy

    Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 22 participants Est. completion 2014-01 12 sites
    Other conditions: Carcinoma Transitional Cell
    View official trial listing →
  • Completed NCT NCT01856374

    Serial EValuation of multiplE Coronary Artery Diseases by an Optical Coherence Tomography; Assessment of the Changes of de Novo Lesions and Comparisons of Neointimal Coverage Between Xience Prime® Versus Cypher SelectTM Stents; SEVEN-Xience Study

    Not yet reported Yonsei University 60 participants Est. completion 2014-10 1 site
    Other conditions: Multi-vessel Diseases, Angina
    View official trial listing →
  • Withdrawn NCT NCT01864070

    Phase 1 TheraSphere + Everolimus With Neuroendocrine Tumors (NETs) + Liver Only or Liver Dominant Disease

    Not yet reported M.D. Anderson Cancer Center
    Other conditions: Liver Cancer
    View official trial listing →
  • Completed NCT NCT01865747

    A Study of Cabozantinib (XL184) vs Everolimus in Subjects With Metastatic Renal Cell Carcinoma

    Not yet reported Exelixis 658 participants Est. completion 2021-01-15 205 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01869114

    Sirolimus and Azacitidine in Treating Patients With High Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia That is Recurrent or Not Eligible for Intensive Chemotherapy

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 57 participants Est. completion 2024-01-03 5 sites Stand-alone
    Other conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), de Novo Myelodysplastic Syndromes, Myelodysplastic Syndrome With Isolated Del(5q), Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia
    View official trial listing →
  • Status unknown NCT NCT01874002

    Prospective Registry to Asses the Long-term Safety and Performance of the Combo Stent

    Robbert J de Winter 1000 participants Est. completion 2019-03 9 sites
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT01878786

    A Pilot Study Comparing the Safety and Efficacy of Everolimus With Other Medicines in Recipients of ECD/DCD Kidneys

    Not yet reported, Not yet reported Matthew Cooper 25 participants Est. completion 2017-12 1 site Stand-alone
    Other conditions: Delayed Graft Function
    View official trial listing →
  • Status unknown NCT NCT01879358

    Sirolimus Eluting ORSIRO Stent Versus Biolimus-eluting NOBORI Stent

    Not yet reported Odense University Hospital 2314 participants Est. completion 2021-02-01 1 site
    Cardiovascular disease Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Completed NCT NCT01880749

    Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas

    Not yet reported NYU Langone Health 5 participants Est. completion 2019-12 1 site
    Other conditions: Neurofibromatosis Type 2, Vestibular Schwannomas, Meningiomas
    View official trial listing →
  • Status unknown NCT NCT01880879

    A Prospective Multicenter Trial Evaluating Helios Biodegradable Polymer SES Safety and Effectiveness in CAD Treatment

    Not yet reported Kinhely Bio-tech Co., Ltd. 800 participants Est. completion 2015-01 1 site
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT01885689

    Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia

    Not yet reported City of Hope Medical Center 72 participants Est. completion 2026-09-21 1 site Stand-alone
    Other conditions: Adult Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Adult Acute Myeloid Leukemia in Remission, Myelodysplastic Syndrome, Secondary Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, Therapy-Related Myelodysplastic Syndrome
    View official trial listing →
  • Completed NCT NCT01887704

    Effect of Rotablator on Balloon Resistant Calcified Coronary Lesion

    Not yet reported Capital Medical University 240 participants Est. completion 2013-05 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT01888042

    Assessing Everolimus in Fist Line Treatment on Patients With Metastatic Kidney Cancer

    Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 61 participants Est. completion 2014-07 1 site
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT01888302

    Sirolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients At High Risk for Cholangiocarcinoma Recurrence After Liver Transplant or Surgery

    Not yet reported Mayo Clinic 1 participants Est. completion 2016-06 1 site Stand-alone
    Other conditions: Hepatic Complication
    View official trial listing →
  • Completed NCT NCT01888432

    Efficacy and Safety of Everolimus in Liver Transplant Recipients of Living Donor Liver Transplants

    Not yet reported Novartis Pharmaceuticals 285 participants Est. completion 2018-04-21 42 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Terminated NCT NCT01889420

    Phase I Trial of Everolimus, Pomalidomide and Dexamethasone in Patients With Relapsed/Refractory Multiple Myeloma

    Not yet reported New Mexico Cancer Research Alliance 1 participants Est. completion 2015-07 1 site
    Other conditions: Multiple Myeloma in Relapse
    View official trial listing →
  • Terminated NCT NCT01889992

    Cardiac Allograft Remodeling and Effects of Sirolimus

    Not yet reported University of Nebraska 42 participants Est. completion 2018-09-27 1 site Stand-alone
    Other conditions: Cardiac Hypertrophy, Immunosuppression
    View official trial listing →
  • Completed NCT NCT01895049

    Comparison Between Two Tacrolimus-based Immunosuppressant Regimens and Induction With Thymoglobulin in Kidney Transplants From Deceased Donors With Expanded Criteria

    Not yet reported Helio Tedesco Silva Junior 171 participants Est. completion 2017-03-07 1 site
    Other conditions: Kidney Transplantation, Cytomegalovirus
    View official trial listing →
  • Completed NCT NCT01902160

    Temsirolimus and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

    Not yet reported National Cancer Institute (NCI) 3 participants 1 site
    Other conditions: Recurrent Adult Hodgkin Lymphoma
    View official trial listing →
  • Terminated NCT NCT01903473

    Donor Regulatory T Cells Infusion in Patients With Chronic Graft-versus-host Disease (GVHD)

    Not yet reported University of Liege 19 participants Est. completion 2022-09-12 2 sites
    Other conditions: Chronic Graft-Versus-Host Disease, Acute Graft-Versus-Host Disease, Steroid Refractory Graft-Versus-Host Disease
    View official trial listing →
  • Completed NCT NCT01909869

    A Pilot First In Man Study of EXCEL-Ⅱto Treat the Patients With de Novo Coronary Artery Lesions

    Not yet reported JW Medical Systems Ltd 45 participants Est. completion 2019-06-04 1 site Stand-alone
    Cardiovascular disease Other conditions: Ischemia
    View official trial listing →
  • Completed NCT NCT01911546

    Role of Everolimus in Highly Sensitized Patients

    Not yet reported Joseph Kahwaji, MD, MPH 20 participants Est. completion 2016-01-19 1 site
    Other conditions: Highly-sensitized Kidney Transplant Recipients
    View official trial listing →
  • Completed NCT NCT01914770

    Effectiveness of Belimumab Treatment in a Subpopulation of Systemic Lupus Erythematosus (SLE) Patients: a Pooled Analysis of BLISS-52 and BLISS-76

    GlaxoSmithKline 1016 participants Est. completion 2010-11
    Other conditions: Systemic Lupus Erythematosus
    View official trial listing →
  • Completed NCT NCT01920061

    A Study Of PF-05212384 In Combination With Other Anti-Tumor Agents and in Combination With Cisplatin in Patients With Triple Negative Breast Cancer in an Expansion Arm (TNBC)

    Not yet reported Pfizer 110 participants Est. completion 2020-01-08 29 sites
    Other conditions: Neoplasm
    View official trial listing →
  • Completed NCT NCT01924962

    Recovery of Left Ventricular Function in Chronic Total Occluded Coronary Arteries

    Not yet reported University Heart Center Freiburg - Bad Krozingen 205 participants Est. completion 2017-06-16 1 site
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Status unknown NCT NCT01925027

    Efficacy and Safety of Nano+ Polymer-free Sirolimus-Eluting Stent: A Optical Coherent Tomography Study

    Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 45 participants Est. completion 2016-11 5 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01927120

    In Vivo Treg Expansion and Graft-Versus-Host Disease Prophylaxis

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 20 participants Est. completion 2017-03-09 1 site Stand-alone
    Other conditions: Graft-Versus-Host-Disease
    View official trial listing →
  • Status unknown NCT NCT01927588

    Evaluation of Early Use of Everolimus (EVE) on Cytomegalovirus (CMV) Infection in Renal Transplant Recipients

    Not yet reported Fundação Pró Rim 50 participants Est. completion 2015-11
    Other conditions: Cytomegalovirus Infections
    View official trial listing →
  • Completed NCT NCT01929642

    Rapalogues for Autism Phenotype in TSC: A Feasibility Study

    Not yet reported Hugo W. Moser Research Institute at Kennedy Krieger, Inc. 3 participants Est. completion 2016-08 1 site Stand-alone
    Other conditions: Tuberous Sclerosis Complex, Self-injury, Autism
    View official trial listing →
  • Completed NCT NCT01931163

    NECTAR Everolimus Plus Cisplatin in Triple (-) Breast Cancer

    Not yet reported Jenny C. Chang, MD 24 participants Est. completion 2019-01 3 sites
    Other conditions: Breast Cancer, Triple Negative Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT01932177

    EVESOR: a Phase 1 Trial of Everolimus and Sorafenib

    Not yet reported Hospices Civils de Lyon 60 participants Est. completion 2015-10 1 site
    Other conditions: Metastatic or Locally Advanced Solid Tumors
    View official trial listing →
  • Completed NCT NCT01935128

    Evaluation of Calcineurin-inhibitor Reduction With Conversion at 2 Months to Everolimus/Reduced Tacrolimus in Renal Transplant Recipients Following Campath® Induction

    Not yet reported University of Toledo Health Science Campus 55 participants Est. completion 2020-07 1 site
    Other conditions: Renal Transplant
    View official trial listing →
  • Completed NCT NCT01936519

    Conversion to Everolimus From Calcineurin Inhibitor With Mycophenolic Acid: Impact on Long Term Renal Function in Liver Transplantation.

    Not yet reported Milton S. Hershey Medical Center 24 participants Est. completion 2019-07-31 1 site
    Other conditions: Immunosuppression, Renal Failure
    View official trial listing →
  • Completed NCT NCT01938573

    Sirolimus, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Bladder Cancer

    Not yet reported, Not yet reported University of Washington 21 participants Est. completion 2016-08-18 2 sites Stand-alone
    Other conditions: Recurrent Bladder Carcinoma, Stage II Bladder Cancer, Stage III Bladder Cancer, Stage IV Bladder Cancer
    View official trial listing →
  • Terminated NCT NCT01939418

    Phase Ib/II Trials of RAD001 in Triple Negative Metastatic Breast Cancer

    Not yet reported, Not yet reported National Cancer Center, Korea 23 participants Est. completion 2017-07-30 1 site
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT01946529

    Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors

    Not yet reported St. Jude Children's Research Hospital 24 participants Est. completion 2026-04-09 1 site
    Other conditions: Desmoplastic Small Round Cell Tumor, Ewing Sarcoma of Bone or Soft Tissue, Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Metastatic Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor
    View official trial listing →
  • Completed NCT NCT01950819

    Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM)

    Not yet reported Novartis Pharmaceuticals 2037 participants Est. completion 2018-01-17 184 sites
    Chronic kidney disease Other conditions: End Stage Renal Disease (ESRD), Hemodialysis, Renal Replacement Therapy, Renal Transplantation
    View official trial listing →
  • Terminated NCT NCT01952847

    Randomized Trial of Glutamine in Patients With Mucositis or Esophagitis

    Not yet reported M.D. Anderson Cancer Center 77 participants Est. completion 2021-03-03 1 site
    Other conditions: Advanced Cancers
    View official trial listing →
  • Status unknown NCT NCT01954693

    A Study of Everolimus in the Treatment of Neurocognitive Problems in Tuberous Sclerosis

    Not yet reported Cardiff University 48 participants Est. completion 2018-08-06 1 site
    Other conditions: Tuberous Sclerosis
    View official trial listing →
  • Completed NCT NCT01958190

    Study Comparing in Livertransplantation Recipients With Tacrolimus Alone Versus Tacrolimus&Sirolimus

    Not yet reported Foundation for Liver Research 196 participants Est. completion 2021-05-20 3 sites Stand-alone
    Other conditions: Liver Disease
    View official trial listing →
  • Status unknown NCT NCT01960829

    Everolimus in Selected Patients With Metastatic Melanoma: Efficacy and Safety Study

    Not yet reported Peking University Cancer Hospital & Institute 60 participants 1 site
    Other conditions: Melanoma, TOR Serine-Threonine Kinases, Neoplasm Metastasis
    View official trial listing →
  • Terminated NCT NCT01962896

    A Phase II Study of Sirolimus and Erlotinib in Recurrent/Refractory Germ Cell Tumors

    Not yet reported Theodore Laetsch 4 participants Est. completion 2018-01-27 3 sites Stand-alone
    Other conditions: Relapsed / Recurrent Germ Cell Tumors
    View official trial listing →
  • Completed NCT NCT01964014

    Once-a-day Immunosuppression(CISECON_a_day)

    Not yet reported Ajou University School of Medicine 160 participants Est. completion 2015-10 7 sites Stand-alone
    Other conditions: Chronic Renal Disease
    View official trial listing →
  • Completed NCT NCT01971684

    ICON1: Treatment Decisions and Outcomes in Pediatric Refractory ITP

    Boston Children's Hospital 120 participants Est. completion 2017-04 29 sites
    Other conditions: Immune Thrombocytopenia
    View official trial listing →
  • Completed NCT NCT01976390

    Comparing Everolimus and Sirolimus in Renal Transplant Recipients

    Not yet reported Ohio State University 60 participants Est. completion 2019-08-31 1 site
    Other conditions: Renal Failure
    View official trial listing →
  • Status unknown NCT NCT01981304

    Effects of a rapamycIn-eluting carboNized Stent With a Completely biodEgradable polymeR Coating

    University of Roma La Sapienza 50 participants Est. completion 2016-12
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT01991938

    Phase I Dose Escalation Study of VS-5584 in Subjects With Advanced Non-Hematologic Malignancies or Lymphoma

    Not yet reported Verastem, Inc. 75 participants Est. completion 2016-12 5 sites
    Other conditions: Non Hematologic Cancers, Metastatic Cancer, Lymphoma
    View official trial listing →
  • Withdrawn NCT NCT01997255

    Adjunctive Everolimus (RAD 001) Therapy for Epilepsy in Children With Sturge-Weber Syndrome (SWS)

    Not yet reported Baylor College of Medicine Est. completion 2016-04 1 site
    Other conditions: Sturge Weber Syndrome
    View official trial listing →
  • Status unknown NCT NCT01998789

    Everolimus Post Orthotopic Liver Transplant

    Not yet reported Tomoaki Kato 50 participants Est. completion 2019-02 1 site
    Other conditions: Orthotopic Liver Transplant
    View official trial listing →
  • Suspended NCT NCT02008019

    A Phase II Study of EVEROLIMUS in Patients With Primary or Relapsed Chondrosarcomas

    Not yet reported Centre Leon Berard 57 participants Est. completion 2019-08 12 sites
    Obstructive sleep apnea
    View official trial listing →
  • Completed NCT NCT02008877

    SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)

    Not yet reported, Not yet reported Sarcoma Alliance for Research through Collaboration 20 participants Est. completion 2018-07 7 sites Stand-alone
    Other conditions: Malignant Peripheral Nerve Sheath Tumors (MPNST), Sarcoma
    View official trial listing →
  • Completed NCT NCT02009332

    Phase 1/2 Study of ABI-009 in Nonmuscle Invasive Bladder Cancer

    Not yet reported, Not yet reported Aadi Bioscience, Inc. 21 participants Est. completion 2019-12-01 2 sites Stand-alone
    Other conditions: Non-muscle Invasive Bladder Cancer (NMIBC)
    View official trial listing →
  • Status unknown NCT NCT02013089

    A Pilot Study of Genomic Sequencing Guided Individualized Therapy in Gastrointestinal Cancers, GITIC Study

    Not yet reported Sun Yat-sen University 50 participants Est. completion 2017-12 1 site
    Other conditions: Gastrointestinal Cancers
    View official trial listing →
  • Terminated NCT NCT02013375

    SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCD

    Not yet reported Damiano Rondelli, MD 2 participants Est. completion 2018-09-07 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Status unknown NCT NCT02015728

    Selecting Patient-Specific Biologically Targeted Therapy for Pediatric Patients With Refractory Or Recurrent Brain Tumors

    Not yet reported Seattle Children's Hospital 20 participants Est. completion 2017-12 1 site
    Other conditions: Recurrent Childhood Brain Tumor
    View official trial listing →
  • Completed NCT NCT02017275

    Comparison of BuMA eG Based BioDegradable Polymer Stent With EXCEL Biodegradable Polymer Sirolimus-eluting Stent in "Real-World" Practice

    Not yet reported Sino Medical Sciences Technology Inc. 2348 participants 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02017860

    Study to Collect and Assess Long-term Safety of Everolimus in Patients Who Are on Everolimus Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator.

    Not yet reported Novartis Pharmaceuticals 4 participants Est. completion 2019-04-25 4 sites
    Other conditions: Neoplasms
    View official trial listing →
  • Completed NCT NCT02019693

    A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer

    Not yet reported National Cancer Institute (NCI) 20 participants Est. completion 2021-12-17 1 site
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT02023359

    Danish Observational Study of Everolimus Plus Exemestane in Hormone Receptor (HR) Positive, Human Epidermal Growth Factor 2 (HER2) - Metastatic Breast Cancer

    Novartis Healthcare A/S 7 participants Est. completion 2015-04 3 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT02023905

    Everolimus With and Without Temozolomide in Adult Low Grade Glioma

    Not yet reported University of California, San Francisco 27 participants Est. completion 2021-09-30 1 site
    Other conditions: Low Grade Glioma, World Health Organization (WHO) Grade II Astrocytomas, Oligodendrogliomas, Mixed Oligoastrocytomas
    View official trial listing →
  • Status unknown NCT NCT02025712

    Exemestane Plus Everolimus for Hormone-receptor Positive Metastatic Breast Cancer

    Not yet reported Organisation for Oncology and Translational Research 35 participants 1 site
    Other conditions: Hormone Receptor Positive Malignant Neoplasm of Breast
    View official trial listing →
  • Completed NCT NCT02027870

    EXCEL-II DES to Treat the Patients With de Novo Coronary Artery Lesions. (CREDIT-III)

    JW Medical Systems Ltd 625 participants Est. completion 2019-11-07 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02028364

    Pet Imaging as a Biomarker in Hormone Refractory postmenopausaL Women

    Not yet reported Jules Bordet Institute 55 participants Est. completion 2021-08-09 5 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT02031536

    Everolimus in Patients With Pancreatic Neuroendocrine Tumors Metastatic to the Liver Previously Treated With Surgery

    Not yet reported ECOG-ACRIN Cancer Research Group 2 participants Est. completion 2017-07-19 1 site
    Other conditions: Gastrinoma, Glucagonoma, Insulinoma, Liver Metastases, Pancreatic Polypeptide Tumor, Recurrent Islet Cell Carcinoma, Somatostatinoma
    View official trial listing →
  • Status unknown NCT NCT02036554

    Evaluate Efficacy Study of Combination Therapy of Everolimus and Low Dose Tacrolimus in Renal Allograft Recipients

    Not yet reported Seoul St. Mary's Hospital 234 participants Est. completion 2015-12 1 site
    Other conditions: Kidney; Complications, Allograft
    View official trial listing →
  • Withdrawn NCT NCT02038478

    Allograft for Sickle Cell Disease and Thalassemia

    Not yet reported University of Texas Southwestern Medical Center Est. completion 2021-05 1 site Stand-alone
    Other conditions: Sickle Cell Disease and Thalassemia
    View official trial listing →
  • Completed NCT NCT02048384

    A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 22 participants Est. completion 2019-09 2 sites
    Other conditions: Metastatic Pancreatic Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT02049047

    Study of Everolimus in Patients With Thymoma and Thymic Carcinoma Previously Treated With Chemotherapy

    Not yet reported Armando Santoro, MD 41 participants Est. completion 2019-01 1 site
    Other conditions: Thymoma and Thymic Carcinoma
    View official trial listing →
  • Status unknown NCT NCT02055079

    Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease

    Not yet reported Medical University of Vienna 68 participants Est. completion 2019-12 1 site Stand-alone
    Other conditions: Polycystic Kidney, Type 1 Autosomal Dominant Disease, Polycystic Kidney, Type 2 Autosomal Dominant Disease
    View official trial listing →
  • Completed NCT NCT02056587

    Everolimus in Patients With Metastatic Renal Cell Carcinoma Following Progression on Prior Bevacizumab Treatment

    Not yet reported Kidney Cancer Research Bureau 37 participants Est. completion 2013-10 3 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Active, not recruiting NCT NCT02057133

    A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread

    Not yet reported Eli Lilly and Company 198 participants Est. completion 2026-12 13 sites
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Completed NCT NCT02057978

    EXCEL-II Stent Vesus EXCEL Stent to Treat the Patients With de Novo Coronary Artery Lesions.

    JW Medical Systems Ltd 419 participants Est. completion 2019-12-25 1 site
    Cardiovascular disease Other conditions: Myocardial Ischemia, Coronary Disease, Heart Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Vascular Diseases
    View official trial listing →
  • Completed NCT NCT02061397

    Safety of Simvastatin in LAM and TSC

    Not yet reported, Not yet reported University of Pennsylvania 10 participants Est. completion 2019-12-13 1 site Stand-alone
    Other conditions: Lymphangioleiomyomatosis, Tuberous Sclerosis Complex
    View official trial listing →
  • Status unknown NCT NCT02061800

    CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

    Not yet reported, Not yet reported Diane George 14 participants Est. completion 2026-07 1 site Stand-alone
    Other conditions: Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML), Myelodysplastic Syndrome (MDS), Juvenile Myelomonocytic Leukemia (JMML), Acute Lymphoblastic Leukemia (ALL), Lymphoma (Hodgkin's and Non-Hodgkin's)
    View official trial listing →
  • Withdrawn NCT NCT02062892

    Differentiating Everolimus Versus Sirolimus in Combination With Calcineurin Inhibitors in Kidney Transplant Patients

    Not yet reported University of Colorado, Denver Est. completion 2014-06 Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT02062944

    SRL (Sirolimus) Withdrawal

    Not yet reported Northwestern University 21 participants Est. completion 2020-07 1 site Stand-alone
    Other conditions: Acute Rejection of Liver Transplant, Effects of Immunosuppressant Therapy
    View official trial listing →
  • Completed NCT NCT02064608

    Investigating the Effects of AZD2014 Therapy Given Prior to Radical Prostatectomy in Men With High Risk Prostate Cancer

    Not yet reported Cambridge University Hospitals NHS Foundation Trust 23 participants Est. completion 2018-06 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT02069093

    Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer

    Not yet reported Novartis Pharmaceuticals 92 participants Est. completion 2016-03 23 sites
    Other conditions: Advanced Breast Cancer
    View official trial listing →
  • Completed NCT NCT02071862

    Study of the Glutaminase Inhibitor CB-839 in Solid Tumors

    Not yet reported Calithera Biosciences, Inc 210 participants Est. completion 2019-03 13 sites
    Other conditions: Solid Tumors, Triple-Negative Breast Cancer, Non Small Cell Lung Cancer, Renal Cell Carcinoma, Mesothelioma, Fumarate Hydratase (FH)-Deficient Tumors, Succinate Dehydrogenase (SDH)-Deficient Gastrointestinal Stromal Tumors (GIST), Succinate Dehydrogenase (SDH)-Deficient Non-gastrointestinal Stromal Tumors, Tumors Harboring Isocitrate Dehydrogenase-1 (IDH1) and IDH2 Mutations, Tumors Harboring Amplifications in the cMyc Gene
    View official trial listing →
  • Completed NCT NCT02073565

    HARMONEE - Japan-USA Harmonized Assessment by Randomized, Multi-Center Study of OrbusNEich's Combo StEnt

    Not yet reported OrbusNeich 572 participants Est. completion 2021-12 50 sites Stand-alone
    Other conditions: Coronary Arteriosclerosis, Non ST Segment Elevation Acute Coronary Syndrome
    View official trial listing →
  • Status unknown NCT NCT02076516

    Pilot Evaluation Of CORACTO® (THE PILOT-SECRET TRIAL)

    Not yet reported Alvimedica 100 participants Est. completion 2015-05 5 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02077556

    Effect of Everolimus on the Pharmacokinetics of Tacrolimus in Renal Transplant Patients

    Not yet reported National Taiwan University Hospital 14 participants Est. completion 2019-01-15 1 site
    Other conditions: Drug Interaction Potentiation
    View official trial listing →
  • Completed NCT NCT02077933

    Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors

    Not yet reported Novartis Pharmaceuticals 79 participants Est. completion 2019-04-12 22 sites
    Other conditions: Neoplasms, Breast Neoplasms, Kidney Neoplasms, Pancreatic Neuroendocine Neoplasms (pNETs)
    View official trial listing →
  • Completed NCT NCT02080624

    Efficacy and Safety Study of Topical Rapamycin Associated With Pulsed Dye Laser in Patients With Sturge-Weber Syndrome

    Not yet reported Clinica Universidad de Navarra, Universidad de Navarra 23 participants Est. completion 2012-12 1 site
    Other conditions: Sturge- Weber Syndrome
    View official trial listing →
  • Enrolling by invitation NCT NCT02081755

    Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer

    Not yet reported Baylor Research Institute 336 participants Est. completion 2027-03 9 sites
    Other conditions: Carcinoma, Hepatocellular
    View official trial listing →
  • Completed NCT NCT02084446

    Everolimus + Very Low Tacrolimus vs Enteric-coated Mycophenolate Sodium + Low Tacrolimus in de Novo Renal Transplant

    Not yet reported Ronaldo de Matos Esmeraldo, MD 120 participants Est. completion 2017-07 1 site
    Other conditions: Transplantation Infection, Cytomegalovirus Infections
    View official trial listing →
  • Completed NCT NCT02091531

    Dual mTOR Inhibitor MLN0128 in Advanced Castration-Resistant Prostate Cancer (CRPC) Patients

    Not yet reported Memorial Sloan Kettering Cancer Center 9 participants Est. completion 2018-10 1 site
    Other conditions: Metastatic Castration-Resistant Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT02091973

    MicroRNA Expression in Everolimus-based Versus Tacrolimus-based Regimens in Kidney Transplantation

    Not yet reported Chulalongkorn University 50 participants Est. completion 2015-12 1 site
    Other conditions: microRNA Profiles
    View official trial listing →
  • Completed NCT NCT02093598

    POEM STUDY: A Phase IIa Trial in Endometrial Carcinoma With Temsirolimus

    Not yet reported MedSIR 10 participants Est. completion 2014-03 3 sites
    Other conditions: Carcinoma, Endometrioid, mTOR Protein
    View official trial listing →
  • Completed NCT NCT02096107

    Novartis Everolimus Transition

    Not yet reported Medical University of South Carolina 60 participants Est. completion 2017-05 1 site
    Other conditions: Graft Dysfunction, Interstitial Fibrosis
    View official trial listing →
  • Status unknown NCT NCT02099162

    Yonsei OCT (Optical Coherence Tomography) Registry for Evaluation of Efficacy and Safety of Coronary Stenting

    Yonsei University 3000 participants Est. completion 2022-07 1 site
    Cardiovascular disease Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Terminated NCT NCT02102997

    Deutsches Dual Therapy Stent Register

    OrbusNeich 130 participants Est. completion 2017-11 1 site
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT02105766

    Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

    Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 56 participants Est. completion 2027-12-31 1 site Stand-alone
    Other conditions: Sickle Cell Disease, Thalassemia, Stem Cell Transplantation, Graft vs Host Disease
    View official trial listing →
  • Completed NCT NCT02106507

    ARN 509 Plus Everolimus in Men With Progressive Metastatic Castration-Resistant Prostate Cancer After Treatment With Abiraterone Acetate

    Not yet reported Memorial Sloan Kettering Cancer Center 9 participants Est. completion 2021-06-28 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT02109744

    Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients

    Not yet reported, Not yet reported University of Rochester 27 participants Est. completion 2022-01-01 1 site
    Other conditions: Acute Myelogenous Leukemia
    View official trial listing →
  • Status unknown NCT NCT02109913

    Analysis of Tumor Tissue and Circulating Genetic Material in the Blood to Obtain Further Insight in the Effectiveness of Everolimus When Combined With Exemestane

    Not yet reported Amsterdam UMC, location VUmc 175 participants Est. completion 2021-01 28 sites
    Other conditions: Hormone Receptor Positive Malignant Neoplasm of Breast, Metastatic Breast Cancer
    View official trial listing →
  • Terminated NCT NCT02110069

    A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular Tumors

    Not yet reported Boston Children's Hospital 4 participants Est. completion 2020-10-27 7 sites Stand-alone
    Other conditions: Kaposiform Hemangioendothelioma (KHE), Kasabach-Merritt Syndrome, Tufted Angioma
    View official trial listing →
  • Status unknown NCT NCT02112981

    BioMime Vs. Xience Randomised Control Clinical Study

    Not yet reported Meril Life Sciences Pvt. Ltd. 256 participants Est. completion 2019-12-01 15 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02113800

    Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study

    Not yet reported AIO-Studien-gGmbH 40 participants Est. completion 2020-04 1 site
    Other conditions: Poorly Differentiated Malignant Neuroendocrine Carcinoma, Neuroendocrine Carcinoma, Grade 3, Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3, Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma] That Switched to G3, Neuroendocrine Tumor, Grade 3 and Disease Progression as Measured by Response Evaluation Criteria in Solid Tumors (RECIST 1.1.)
    View official trial listing →
  • Completed NCT NCT02115113

    REnal Function in Liver Transplantation: Everolimus With Calcineurin Inhibitor (CNI)-Sparing sTrategy

    Not yet reported Novartis Pharmaceuticals 78 participants Est. completion 2016-09-30 14 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Completed NCT NCT02117596

    Calcineurin Inhibitor Based Immunosuppression Withdrawal

    Not yet reported Pediatric Nephrology of Alabama 52 participants Est. completion 2012-11 4 sites
    Other conditions: Renal Transplant
    View official trial listing →
  • Completed NCT NCT02120469

    Eribulin Mesylate and Everolimus in Treating Patients With Triple-Negative Metastatic Breast Cancer

    Not yet reported City of Hope Medical Center 27 participants Est. completion 2020-03-03 3 sites
    Other conditions: Estrogen Receptor Negative, HER2/Neu Negative, Progesterone Receptor-negative, Stage IV Breast Cancer, Triple-negative Breast Carcinoma
    View official trial listing →
  • Completed NCT NCT02123823

    BI 836845 in Estrogen Receptor Positive Metastatic Breast Cancer

    Not yet reported Boehringer Ingelheim 164 participants Est. completion 2021-12-14 38 sites
    Other conditions: Neoplasms
    View official trial listing →
  • Terminated NCT NCT02123966

    An Open Label Phase II Trial of Topical Sirolimus for the Treatment of Refractory Oral Chronic Graft-versus-Host-Disease

    Not yet reported Dana-Farber Cancer Institute 10 participants Est. completion 2016-05 2 sites Stand-alone
    Obstructive sleep apnea Other conditions: Chronic Graft-versus-Host-Disease
    View official trial listing →
  • Completed NCT NCT02125084

    Enzalutamide Plus Everolimus in Men With Metastatic Castrate-Resistant Prostate Cancer

    Not yet reported SCRI Development Innovations, LLC 38 participants Est. completion 2021-05-03 5 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Withdrawn NCT NCT02126527

    Auranofin and Sirolimus in Treating Patients With Advanced Solid Tumors or Recurrent Non-Small Cell Lung Cancer

    Not yet reported Mayo Clinic 1 site Stand-alone
    Other conditions: Recurrent Non-small Cell Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific
    View official trial listing →
  • Status unknown NCT NCT02127138

    The Study of Active Transfer of Plaque Technique for Unprotected Distal Left Main Bifurcation Lesions

    Not yet reported Beijing Anzhen Hospital 316 participants Est. completion 2021-12 1 site Stand-alone
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Status unknown NCT NCT02133287

    To Evaluate The Safety and Efficacy of 'AVI' Stent Comparing With Firebird2® For Treating Coronary Revascularization

    Not yet reported Beijing AmsinoMed Medical Device Co., Ltd 2000 participants Est. completion 2022-11 1 site
    Other conditions: Ischemic Heart Disease, Myocardial Ischemia, Coronary Disease, Acute Coronary Syndrome
    View official trial listing →
  • Terminated NCT NCT02134288

    Belatacept for Renal Transplant Recipients With Delayed Graft Function

    Not yet reported Ohio State University 8 participants Est. completion 2019-01-18 1 site
    Other conditions: Delayed Graft Function
    View official trial listing →
  • Completed NCT NCT02134899

    The Efficacy of Everolimus in Reducing Total Native Kidney Volume in Polycystic Kidney Disease Transplanted Recipients

    Not yet reported Assistance Publique - Hôpitaux de Paris 3 participants Est. completion 2017-11-11 1 site
    Other conditions: Autosomal Dominant Polycystic Kidney Disease
    View official trial listing →
  • Completed NCT NCT02137239

    Regimen Optimization Study

    Not yet reported Bristol-Myers Squibb 58 participants Est. completion 2019-05-02 20 sites
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Terminated NCT NCT02137837

    S1222 Trial (Everolimus, Anastrozole and Fulvestrant) in Post-Menopausal Stage IV Breast Cancer

    Not yet reported SWOG Cancer Research Network 37 participants Est. completion 2019-12-31 223 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT02138929

    LDE225 + Everolimus in Advanced Gastroesophageal Adenocarcinoma

    Not yet reported M.D. Anderson Cancer Center 25 participants Est. completion 2020-06-08 1 site
    Other conditions: Esophageal Cancer
    View official trial listing →
  • Completed NCT NCT02142036

    N-of-1 Trial: Actionable Target Identification in Metastatic Cancer for Palliative Systemic Therapy

    Not yet reported Oslo University Hospital 50 participants Est. completion 2018-08 2 sites
    Other conditions: Metastatic Cancer
    View official trial listing →
  • Completed NCT NCT02145559

    A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors

    Not yet reported University of Chicago 24 participants Est. completion 2018-07 1 site Stand-alone
    Other conditions: Breast Neoplasms, Lung Neoplasms, Cancer of Liver, Lymphoma, Cancer of Kidney
    View official trial listing →
  • Completed NCT NCT02152007

    Topical Sirolimus for the Treatment of Pachyonychia Congenita (PC)

    Not yet reported TransDerm, Inc. 15 participants Est. completion 2015-11 1 site Stand-alone
    Other conditions: Pachyonychia Congenita
    View official trial listing →
  • Completed NCT NCT02152943

    Everolimus, Letrozole and Trastuzumab in HR- and HER2/Neu-positive Patients

    Not yet reported M.D. Anderson Cancer Center 37 participants Est. completion 2020-12-14 5 sites
    Other conditions: Advanced Malignant Solid Neoplasm, Estrogen Receptor Positive, HER2/Neu Positive, Postmenopausal, Premenopausal, Progesterone Receptor Positive, Recurrent Breast Carcinoma, Refractory Breast Carcinoma, Refractory Hormone Receptor Positive Breast Carcinoma, Stage IIIA Breast Cancer AJCC v7, Stage IIIB Breast Cancer AJCC v7, Stage IIIC Breast Cancer AJCC v7, Stage IV Breast Cancer AJCC v6 and v7
    View official trial listing →
  • Completed NCT NCT02155920

    Everolimus for Children With Recurrent or Progressive Ependymoma

    Not yet reported University of Texas Southwestern Medical Center 11 participants Est. completion 2023-07-14 4 sites
    Other conditions: Recurrent Childhood Ependymoma
    View official trial listing →
  • Completed NCT NCT02165007

    Haploidentical Hematopoietic Stem Cell Transplantation

    Not yet reported Catherine Bollard 7 participants Est. completion 2024-10 1 site Stand-alone
    Other conditions: Sickle Cell-thalassemia Disease, Thalassemia
    View official trial listing →
  • Completed NCT NCT02166177

    Safety and Efficacy Study of Regulatory T Cell Therapy in Liver Transplant Patients

    Not yet reported, Not yet reported Guy's and St Thomas' NHS Foundation Trust 9 participants Est. completion 2018-01-22 1 site Stand-alone
    Other conditions: End-stage Liver Disease
    View official trial listing →
  • Withdrawn NCT NCT02177760

    Sirolimus Prophylaxis for aGVHD in TME SCID

    Not yet reported University of California, San Francisco Est. completion 2015-11 1 site Stand-alone
    Other conditions: Severe Combined Immunodeficiency, Transplacental Maternal Engraftment, Stem Cell Transplant
    View official trial listing →
  • Completed NCT NCT02183454

    MASCOT - Post Marketing Registry

    OrbusNeich 2500 participants Est. completion 2017-05-31 1 site
    Cardiovascular disease Other conditions: Atherosclerosis
    View official trial listing →
  • Completed NCT NCT02184416

    Study Of The Impact Of Inlyta In 2nd Line On The Treatment Outcomes Of mRCC Patients Treated With Sutent In 1st Line In The Real Life Setting

    Pfizer 554 participants Est. completion 2022-09-30 110 sites
    Other conditions: Metastatic Renal Cell Carcinoma (mRCC)
    View official trial listing →
  • Completed NCT NCT02187302

    CRLX101(NLG207) in Combination With Bevacizumab for Metastatic Renal Cell Carcinoma (mRCC) Versus Standard of Care (SOC)

    Not yet reported NewLink Genetics Corporation 115 participants Est. completion 2017-01 43 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT02188550

    Single Arm Trial With Combination of Everolimus and Letrozole in Treatment of Platinum Resistant Relapse or Refractory or Persistent Ovarian Cancer/Endometrial Cancer

    Not yet reported Sinai Hospital of Baltimore 20 participants 1 site
    Other conditions: Ovarian Cancer, Endometrial Cancer
    View official trial listing →
  • Terminated NCT NCT02188719

    Donor-Alloantigen-Reactive Regulatory T Cell (darTregs) in Liver Transplantation

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 15 participants Est. completion 2019-06-18 3 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Status unknown NCT NCT02195414

    NeoVas Bioresorbable Coronary Scaffold First-in-Man Study

    Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 31 participants Est. completion 2019-09 2 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02198300

    DES Versus BiOSS LIM - POLBOS II Study

    Not yet reported Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland 202 participants Est. completion 2015-03 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02201212

    Everolimus for Cancer With TSC1 or TSC2 Mutation

    Not yet reported Dana-Farber Cancer Institute 30 participants Est. completion 2019-06 2 sites
    Other conditions: TSC1, TSC2, Tuberous Sclerosis Complex, MTOR
    View official trial listing →
  • Completed NCT NCT02205515

    An Open Label, Single-Centre, Pilot Study of Everolimus With EBRT for the Treatment of mNET Liver Metastasis

    Not yet reported, Not yet reported Sunnybrook Health Sciences Centre 17 participants Est. completion 2021-10 1 site
    Other conditions: Carcinoma, Neuroendocrine
    View official trial listing →
  • Status unknown NCT NCT02208128

    Molecular Determinants for Therapy Response on Renal Cell Carcinoma

    Not yet reported Heidelberg University 4 participants Est. completion 2018-02 1 site
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT02208791

    Effects of the Quadruple Immunosuppression on Peripheral Blood Lymphocytes and Development of Anti-HLA Antibodies in Kidney Transplant

    Not yet reported University of Sao Paulo General Hospital 45 participants Est. completion 2017-07 1 site Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Terminated NCT NCT02214706

    Treatment of Port Wine Stains Using Pulsed Dye Laser, Erbium Yag Laser and Topical Sirolimus

    Not yet reported Erasmus Medical Center 17 participants Est. completion 2016-12 1 site Stand-alone
    Other conditions: Port-Wine Stain
    View official trial listing →
  • Completed NCT NCT02215720

    Temsirolimus and Cetuximab in Patients With Advanced or Metastatic Solid Tumors

    Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 45 participants Est. completion 2016-05-04 1 site
    Other conditions: Patients With Advanced or Metastatic Solid Tumors
    View official trial listing →
  • Status unknown NCT NCT02216058

    Safety and Efficacy Study of NOYA Sirolimus-Eluting Stent to Treat Coronary Artery Disease

    Not yet reported Medfavour (Beijing) Medical Co., Ltd 2000 participants Est. completion 2020-06 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02216786

    A Randomized Study of AZD2014 in Combination With Fulvestrant in Metastatic or Advanced Breast Cancer

    Not yet reported Queen Mary University of London 333 participants Est. completion 2021-12-31 79 sites
    Other conditions: Estrogen Receptor Positive Breast Cancer
    View official trial listing →
  • Completed NCT NCT02226861

    Ultra-Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantation

    Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 24 participants Est. completion 2018-06-27 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML), Chronic Lymphocytic Leukemia (CLL), Chronic Myelogenous Leukemia (CML), MDS
    View official trial listing →
  • Completed NCT NCT02228681

    Everolimus and Letrozole or Hormonal Therapy to Treat Endometrial Cancer

    Not yet reported GOG Foundation 74 participants Est. completion 2024-08-22 26 sites
    Other conditions: Advanced, Persistent, or Recurrent Endometrial Cancer
    View official trial listing →
  • Status unknown NCT NCT02233049

    Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication

    Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 250 participants Est. completion 2018-10 1 site
    Other conditions: Diffuse Intrinsic Pontine Glioma
    View official trial listing →
  • Terminated NCT NCT02236572

    Neoadj ph 2 AI Plus Everolimus in Postmenopausal Women w/ ER Pos/HER2 Neg, Low Risk Score

    Not yet reported Yale University 17 participants Est. completion 2021-03-01 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT02236975

    First-in-man Trial Examining the Safety and Efficacy of BuMA Supreme and Resolute Integrity in Patients With de Novo Coronary Artery Stenosis

    Not yet reported, Not yet reported Sino Medical Sciences Technology Inc. 168 participants Est. completion 2019-03 12 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02238496

    Perifosine and Torisel (Temsirolimus) for Recurrent/Progressive Malignant Gliomas

    Not yet reported Andrew B Lassman, MD 10 participants Est. completion 2021-02-14 2 sites
    Other conditions: Brain Tumor, Recurrent, Glioblastoma, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma, Mixed Glioma
    View official trial listing →
  • Completed NCT NCT02240407

    Re-administration of Intramuscular AAV9 in Patients With Late-Onset Pompe Disease

    Not yet reported University of Florida 2 participants Est. completion 2021-08-26 1 site Stand-alone
    Other conditions: Pompe Disease
    View official trial listing →
  • Completed NCT NCT02240719

    Everolimus and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory Hematologic Cancer

    Not yet reported University of California, Davis 20 participants Est. completion 2018-04-09 1 site
    Other conditions: Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Refractory Chronic Lymphocytic Leukemia, Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT02241564

    Malignancies in Transplanted Patients

    Uppsala University 95 participants Est. completion 2017-06 1 site
    Other conditions: Neoplasms
    View official trial listing →
  • Completed NCT NCT02246127

    Sequentiality of Everolimus and STZ-5FU in Advanced Pancreatic Neuroendocrine Tumor

    Not yet reported Grupo Espanol de Tumores Neuroendocrinos 141 participants Est. completion 2021-07-12 37 sites
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Completed NCT NCT02248012

    Everolimus and Temozolomide in Advanced Gastroenteropancreatic Neuroendocrine Carcinoma (G3)

    Not yet reported Haukeland University Hospital 38 participants Est. completion 2019-12-01 1 site
    Other conditions: Neuroendocrine Carcinoma
    View official trial listing →
  • Completed NCT NCT02248571

    Patient Preference for Everolimus in Combination With Exemestane or Capecitabine in Combination With Bevacizumab

    Not yet reported iOMEDICO AG 85 participants Est. completion 2017-09-30 1 site
    Other conditions: Breast Cancer Recurrent, HER2/Neu-negative Carcinoma of Breast, Hormone Receptor Positive Malignant Neoplasm of Breast
    View official trial listing →
  • Completed NCT NCT02251938

    A Phase IIIb, Multinational, Multicenter, Open-Label Extension Study Assessing the Long-Term Safety of PRN Intravitreal Injections of DE-109 in Subjects With Non-Infectious Uveitis of the Posterior Segment of the Eye Who Have Participated in the SAKURA Development Program

    Not yet reported Santen Inc. 60 participants Est. completion 2017-11-27 25 sites Stand-alone
    Other conditions: Non-Infectious Uveitis of the Posterior Segment of the Eye
    View official trial listing →
  • Terminated NCT NCT02254239

    Everolimus and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

    Not yet reported Mayo Clinic 10 participants Est. completion 2018-12-12 1 site
    Other conditions: Recurrent Hodgkin Lymphoma, Refractory Hodgkin Lymphoma
    View official trial listing →
  • Status unknown NCT NCT02254668

    Intracoronary Analysis of Cardiac Allograft Vasculopathy by Means of Optical Coherence Tomography

    Not yet reported University of Zurich 278 participants Est. completion 2023-02 1 site
    Other conditions: Intimal Proliferation, Immunosuppression
    View official trial listing →
  • Completed NCT NCT02258451

    Study of Radium-223 Dichloride in Combination With Exemestane and Everolimus Versus Placebo in Combination With Exemestane and Everolimus in Subjects With Bone Predominant HER2 Negative Hormone Receptor Positive Metastatic Breast Cancer

    Not yet reported Bayer 283 participants Est. completion 2022-10-28 92 sites
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Completed NCT NCT02263313

    EGO-COMBO Clinical End-point Extension Study Beyond 36 Months

    The University of Hong Kong 59 participants Est. completion 2014-09 1 site
    Other conditions: Coronary Restenosis
    View official trial listing →
  • Completed NCT NCT02264665

    OPALINE : A Study Of Morbidity And Mortality At 2 Years

    Pfizer 144 participants Est. completion 2019-11-18 35 sites
    Other conditions: Pancreatic Neuroendocrine Tumor, Well Differentiated and Progressive
    View official trial listing →
  • Terminated NCT NCT02269670

    Phase II Study of Everolimus Beyond Progression

    Not yet reported Emory University 3 participants Est. completion 2021-01-25 3 sites
    Other conditions: Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Cancer, Progesterone Receptor-positive Breast Cancer, Recurrent Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer
    View official trial listing →
  • Terminated NCT NCT02273752

    Pharmacokinetically Guided Everolimus in Patients With Breast Cancer, Pancreatic Neuroendocrine Tumors, or Kidney Cancer

    Not yet reported Emory University 2 participants Est. completion 2015-12 2 sites
    Other conditions: Estrogen Receptor-positive Breast Cancer, Gastrinoma, Glucagonoma, HER2-negative Breast Cancer, Insulinoma, Mucositis, Oral Complications, Pancreatic Polypeptide Tumor, Progesterone Receptor-positive Breast Cancer, Recurrent Breast Cancer, Recurrent Islet Cell Carcinoma, Recurrent Renal Cell Cancer, Somatostatinoma, Stage III Renal Cell Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer, Stage IV Renal Cell Cancer
    View official trial listing →
  • Status unknown NCT NCT02279758

    A Pilot Study of Metformin Treatment in Patients With Well-differentiated Neuroendocrine Tumors

    Not yet reported Instituto do Cancer do Estado de São Paulo 30 participants 1 site
    Other conditions: Well-differentiated Neuroendocrine Tumors
    View official trial listing →
  • Terminated NCT NCT02282904

    Haploidentical Transplant for People With Chronic Granulomatous Disease Using Post Transplant Cyclophosphamide

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 7 participants Est. completion 2019-12-10 1 site Stand-alone
    Other conditions: Chronic Granulomatous Disease
    View official trial listing →
  • Completed NCT NCT02283658

    Everolimus and Letrozole in Treating Patients With Recurrent Hormone Receptor Positive Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer

    Not yet reported Mayo Clinic 20 participants Est. completion 2018-06-21 2 sites
    Other conditions: Ovarian Endometrioid Adenocarcinoma, Ovarian Seromucinous Carcinoma, Ovarian Serous Cystadenocarcinoma, Ovarian Serous Surface Papillary Adenocarcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Ovarian Germ Cell Tumor, Recurrent Primary Peritoneal Carcinoma, Undifferentiated Ovarian Carcinoma
    View official trial listing →
  • Completed NCT NCT02291913

    Everolimus Combined With Anti-estrogen Therapy in Hormone-Receptor-Positive HER-2 Negative Advanced Breast Cancer

    Not yet reported SCRI Development Innovations, LLC 48 participants Est. completion 2019-01-31 8 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT02294006

    Activity and Safety of Everolimus+Octreotide LAR+Metformin in Advanced Pancreatic Well-differentiated NETs

    Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 26 participants Est. completion 2021-10 1 site
    Other conditions: Well Differentiated Pancreatic Endocrine Tumor
    View official trial listing →
  • Completed NCT NCT02296749

    Bioavailability Study of Sirolimus Tablets 2 mg Under Fasting Condition

    Not yet reported Dr. Reddy's Laboratories Limited 60 participants Est. completion 2010-02 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02296762

    Bioavailability Study of Sirolimus Tablets 2 mg Under Fed Condition

    Not yet reported Dr. Reddy's Laboratories Limited 36 participants Est. completion 2010-02 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02305472

    NeoVas Bioresorbable Coronary Scaffold Registry Study

    Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 825 participants Est. completion 2020-09 27 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT02305485

    NeoVas Bioresorbable Coronary Scaffold Randomized Controlled Trial

    Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 560 participants Est. completion 2020-06 27 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02305810

    A Biological Prospective Study in Patients With Metastatic Pancreatic NETs Treated With Everolimus

    Not yet reported European Institute of Oncology 54 participants Est. completion 2018-06 1 site
    Other conditions: Pancreatic Neuroendocrine Tumour Metastatic
    View official trial listing →
  • Terminated NCT NCT02306135

    Identifying Mechanisms of Resistance to mTOR Inhibitors in Cancer

    Dartmouth-Hitchcock Medical Center 2 participants Est. completion 2016-03 1 site
    Other conditions: Cancer
    View official trial listing →
  • Status unknown NCT NCT02313051

    Everolimus trIal for Advanced prememopausaL Breast Cancer Patients

    Not yet reported Chinese Academy of Medical Sciences 200 participants Est. completion 2017-12 1 site
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT02314312

    Efficacy and Safety of Everolimus in de Novo Kidney Transplant Recipients of ECD or AKI Donors

    Not yet reported Mahidol University 48 participants Est. completion 2015-06
    Other conditions: Transplantation of Kidney, Expanded Criteria Donor, ECD
    View official trial listing →
  • Terminated NCT NCT02315625

    Study of Mutation-Targeted Therapy With Sunitinib or Everolimus in People With Advanced Low- or Intermediate-Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery

    Not yet reported National Cancer Institute (NCI) 16 participants Est. completion 2019-05-22 1 site
    Other conditions: Neuroendocrine Tumors, Neuroendocrine Carcinoma, Neuroendocrine Neoplasms, Carcinoma, Neuroendocrine, Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas
    View official trial listing →
  • Active, not recruiting NCT NCT02321501

    Ceritinib and Everolimus in Treating Patients With Locally Advanced or Metastatic Solid Tumors or Stage IIIB-IV Non-small Cell Lung Cancer

    Not yet reported M.D. Anderson Cancer Center 37 participants Est. completion 2026-12-31 1 site
    Other conditions: ALK Positive, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, ROS1 Gene Rearrangement, Stage IIIB Lung Non-Small Cell Cancer AJCC v7, Stage IV Lung Non-Small Cell Cancer AJCC v7
    View official trial listing →
  • Completed NCT NCT02328781

    Prospective Evaluation of Safety and Efficacy Vertebral Drug-eluting Stent System

    Not yet reported Zhongrong Miao 101 participants Est. completion 2016-11-25 1 site
    Other conditions: Vertebrobasilar Insufficiency
    View official trial listing →
  • Completed NCT NCT02328963

    Proportion of CMV Seropositive Kidney Transplant Recipients Who Will Develop a CMV Infection When Treated With an Immunosuppressive Regimen Including Everolimus and Reduced Dose of Cyclosporine Versus an Immunosuppressive Regimen With Mycophenolic Acid and Standard Dose of Cyclosporine A

    Not yet reported University Hospital, Bordeaux 186 participants Est. completion 2018-10-10 9 sites
    Other conditions: Transplantation Infection, Cytomegalovirus Infection
    View official trial listing →
  • Completed NCT NCT02329808

    Clinical Validation of a Dried Blood Spot Method for Analysis of Immunosuppressives and Antifungals in Pediatrics

    Radboud University Medical Center 93 participants Est. completion 2021-12-03 1 site
    Other conditions: Hematologic Diseases, Oncology Problem, Kidney Diseases, Transplantation Infection
    View official trial listing →
  • Completed NCT NCT02332902

    Everolimus for Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis1 CRAD001CUS232T

    Not yet reported The University of Texas Health Science Center, Houston 24 participants Est. completion 2016-03 1 site
    Other conditions: Neurofibromatosis 1
    View official trial listing →
  • Completed NCT NCT02333565

    Combination of Everolimus and Octreotide LAR in Aggressive Recurrent Meningiomas

    Not yet reported Assistance Publique Hopitaux De Marseille 20 participants Est. completion 2023-05-24 1 site
    Other conditions: Recurrent Meningiomas, Resistant Meningiomas
    View official trial listing →
  • Completed NCT NCT02334488

    Study Evaluating the Benefit of Two Immunosuppressive Strategies on Renal Function

    Not yet reported Poitiers University Hospital 329 participants Est. completion 2020-07-03 14 sites
    Chronic kidney disease
    View official trial listing →
  • Terminated NCT NCT02338570

    Outcome-related Factors in Patients With Metastatic Renal Cell Carcinoma Treated With Everolimus (ORCHIDEE)

    Not yet reported Mario Negri Institute for Pharmacological Research 31 participants Est. completion 2018-02 8 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT02338609

    Long-term Monitoring of Growth and Development of Pediatric Patients Previously Treated With Everolimus

    Not yet reported Novartis Pharmaceuticals 15 participants Est. completion 2023-12-18 6 sites
    Other conditions: Growth and Development
    View official trial listing →
  • Completed NCT NCT02343718

    Vinblastine and Temsirolimus in Pediatrics With Recurrent or Refractory Lymphoma or Solid Tumours Including CNS Tumours

    Not yet reported Canadian Cancer Trials Group 7 participants Est. completion 2019-01-16 6 sites
    Other conditions: Recurrent Lymphoma, Refractory Lymphoma, Solid Tumours, Central Nervous System
    View official trial listing →
  • Completed NCT NCT02344550

    Study of GnRH-A [Leuprorelin(Lorelin Depot] Plus Leterozole +/- Everolimus for Premenopausal Women With Metastatic Breast Cancer

    Not yet reported Asan Medical Center 137 participants Est. completion 2018-10 1 site
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT02352844

    Everolimus in Patients With Advanced Solid Malignancies With TSC1, TSC2, NF1, NF2, or STK11 Mutations

    Not yet reported Washington University School of Medicine 12 participants Est. completion 2017-08-15 1 site
    Other conditions: Solid Malignancy, Solid Tumor
    View official trial listing →
  • Completed NCT NCT02356159

    Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

    Not yet reported, Not yet reported National Cancer Institute (NCI) 34 participants Est. completion 2025-03-25 2 sites Stand-alone
    Other conditions: Myelodysplastic Syndromes, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Acute Leukemia, Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT02357342

    Sirolimus Versus Anti-Vascular Endothelial Growth Factor (antiVEGF) for Wet AMD

    Not yet reported Maturi, Raj K., M.D., P.C. 40 participants Est. completion 2017-01 1 site Stand-alone
    Other conditions: Age-Related Macular Degeneration
    View official trial listing →
  • Completed NCT NCT02360020

    The XLIMUS-DES in Very Complex Lesions

    Not yet reported Clinica Mediterranea 200 participants Est. completion 2016-05 1 site
    Other conditions: Coronary Atherosclerosis Due to Calcified Coronary Lesion, Chronic Total Occlusion of Coronary Artery
    View official trial listing →
  • Status unknown NCT NCT02360423

    Safety and Efficacy of the CRE8 Stent for the Treatment of De Novo Coronary Artery Lesions

    Not yet reported CID S.p.A. 430 participants Est. completion 2021-04 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT02360709

    Safety and Efficacy of the CRE8 Sirolimus-Eluting Stent for the Treatment of De Novo Coronary Artery Lesions

    CID S.p.A. 800 participants Est. completion 2021-04 1 site
    Cardiovascular disease
    View official trial listing →
  • Withdrawn NCT NCT02365415

    Systemic Rapamycin (Sirolimus) to Prevent In-Stent Restenosis Following Pulmonary Artery Stent Placement

    Not yet reported Boston Children's Hospital Est. completion 2018-04 1 site Stand-alone
    Other conditions: Peripheral Pulmonary Stenosis, In-stent Stenosis
    View official trial listing →
  • Terminated NCT NCT02372227

    A Phase 1 Dose Escalation Study of VS-5584 Administered in Combination With VS-6063, in Subjects With Relapsed Malignant Mesothelioma

    Not yet reported Verastem, Inc. 21 participants Est. completion 2015-10 4 sites
    Other conditions: Relapsed Malignant Mesothelioma
    View official trial listing →
  • Completed NCT NCT02376985

    Evaluation of Oral Care to Prevent Oral Mucositis in ER Positive MBC Patients Treated With Everolimus: Phase 3 RCT

    Not yet reported Comprehensive Support Project for Oncology Research 174 participants Est. completion 2018-10-16 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Withdrawn NCT NCT02384629

    PCI With AXXESS Biolimus A9 Eluting Bifurcation Stent in Treating Coronary Artery Bifurcation Disease

    Not yet reported Yonsei University Est. completion 2017-12 Stand-alone
    Other conditions: Coronary Bifurcation Lesions
    View official trial listing →
  • Completed NCT NCT02384837

    Effect of TCFA on Neointimal Coverage After PCI at 9 Months Follow-up

    General Hospital of Chinese Armed Police Forces 33 participants Est. completion 2016-11 1 site
    Other conditions: Unrecognized Condition
    View official trial listing →
  • Completed NCT NCT02385279

    Study Comparing the MiStent SES Versus the XIENCE EES Stent

    Not yet reported ECRI bv 1398 participants Est. completion 2021-02-04 20 sites Stand-alone
    Other conditions: Coronary Stenosis
    View official trial listing →
  • Active, not recruiting NCT NCT02389309

    Dasatinib, Temsirolimus, and Cyclophosphamide in Treating Patients With Advanced, Recurrent, or Refractory Solid Tumors

    Not yet reported M.D. Anderson Cancer Center 14 participants Est. completion 2027-10-31 1 site
    Other conditions: Advanced Malignant Solid Neoplasm, Recurrent Brain Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory Brain Neoplasm
    View official trial listing →
  • Completed NCT NCT02389946

    Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

    Not yet reported Biotronik, Inc. 1334 participants Est. completion 2021-03 92 sites Stand-alone
    Cardiovascular disease Other conditions: Atherosclerosis, Coronary, Myocardial Ischemia, Ischemic Heart Disease, Acute Coronary Syndrome, Angina Pectoris
    View official trial listing →
  • Active, not recruiting NCT NCT02397083

    Levonorgestrel-Releasing Intrauterine System With or Without Everolimus in Treating Patients With Atypical Hyperplasia or Stage IA Grade 1 Endometrial Cancer

    Not yet reported M.D. Anderson Cancer Center 102 participants Est. completion 2028-09-30 18 sites
    Other conditions: Atypical Endometrial Hyperplasia, FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma
    View official trial listing →
  • Status unknown NCT NCT02398955

    Biomime Stent in All-comers PCI Patients Registry

    Azienda Ospedaliero Universitaria Maggiore della Carita 250 participants Est. completion 2016-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02400632

    MagicTouch Sirolimus Drug Coated Balloon Catheter for the Treatment of Coronary Lesions

    Not yet reported Scitech Produtos Medicos SA 60 participants Est. completion 2019-12-30 3 sites
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT02404051

    Fulvestrant and EVerolimus Plus EXemestane in Metastatic Breast Cancer

    Not yet reported Consorzio Oncotech 745 participants Est. completion 2019-01 41 sites
    Other conditions: Metastatic Breast Cancer, Breast Cancer, Hormone Receptor Positive Tumor, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast, Locally Advanced Malignant Neoplasm
    View official trial listing →
  • Completed NCT NCT02406326

    An Evaluation of BioMime™ - Sirolimus Eluting Coronary Stent in a Multi- Centre Study.

    Meril Life Sciences Pvt. Ltd. 250 participants Est. completion 2016-12-27 11 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02407054

    A Study of Enzalutamide and LY3023414 in Men With Prostate Cancer

    Not yet reported Eli Lilly and Company 142 participants Est. completion 2020-04-16 36 sites
    Other conditions: Prostate Cancer Metastatic
    View official trial listing →
  • Completed NCT NCT02407509

    Phase I Trial of VS-6766 Alone and in Combination With Everolimus

    Not yet reported Royal Marsden NHS Foundation Trust 104 participants Est. completion 2025-10-15 3 sites
    Other conditions: Solid Tumours, Multiple Myeloma, Lung Cancer, Ovarian Cancer
    View official trial listing →
  • Terminated NCT NCT02411084

    Study of BEGEDINA® vs "Conventional Treatment" for Treating Steroid-Resistant Acute GvHD

    Not yet reported Adienne SA 36 participants Est. completion 2017-07-31 27 sites
    Other conditions: Graft vs Host Disease
    View official trial listing →
  • Status unknown NCT NCT02415452

    Researches of Retinal Artery Lesions and Acute Coronary Syndrome

    Capital Medical University 660 participants Est. completion 2018-01
    Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Completed NCT NCT02420613

    Vorinostat and Temsirolimus With or Without Radiation Therapy in Treating Younger Patients With Newly Diagnosed or Progressive Diffuse Intrinsic Pontine Glioma

    Not yet reported M.D. Anderson Cancer Center 18 participants Est. completion 2025-03-28 1 site
    Other conditions: Diffuse Intrinsic Pontine Glioma
    View official trial listing →
  • Completed NCT NCT02423915

    Fucosylated T Cells for Graft Versus Host Disease (GVHD) Prevention

    Not yet reported M.D. Anderson Cancer Center 5 participants Est. completion 2020-10-06 1 site Stand-alone
    Other conditions: Leukemia, Lymphoma
    View official trial listing →
  • Terminated NCT NCT02423954

    Study of Nivolumab Plus Chemotherapy in Patients With Advanced Cancer (NivoPlus)

    Not yet reported, Not yet reported Western Regional Medical Center 33 participants Est. completion 2017-11-01 1 site
    Other conditions: Advanced Cancer, Pancreatic Cancer, Renal Cell Cancer, Non Small Cell Lung Cancer, Colorectal Carcinoma, Endometrial, Uterine
    View official trial listing →
  • Completed NCT NCT02428296

    Study of Sirolimus Therapy for Segmental Overgrowth Caused by Somatic PI3K Activation

    Not yet reported National Human Genome Research Institute (NHGRI) 39 participants Est. completion 2018-02-14 1 site Stand-alone
    Other conditions: PIK3CA-Related Overgrowth Spectrum (PROS), Growth Disorder, Genetics
    View official trial listing →
  • Completed NCT NCT02429869

    Impact of Everolimus on HIV Persistence Post Kidney or Liver Transplant

    Not yet reported University of California, San Francisco 10 participants Est. completion 2018-01-31 1 site
    Other conditions: HIV, Kidney Transplant, Liver Transplant
    View official trial listing →
  • Completed NCT NCT02429973

    Trial With Gemcitabine and Rapamycin in Second Line of Metastatic Osteosarcoma

    Not yet reported Broto, Javier Martín, M.D. 33 participants Est. completion 2015-04
    Obstructive sleep apnea
    View official trial listing →
  • Status unknown NCT NCT02430363

    Evaluation Of The Treatment Effectiveness Of Glioblastoma / Gliosarcoma Through The Suppression Of The PI3K/Akt Pathway In Compared With MK-3475

    Not yet reported, Not yet reported Medical Research Council 58 participants Est. completion 2018-06 13 sites
    Other conditions: Glioblastoma
    View official trial listing →
  • Completed NCT NCT02440789

    Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)

    Not yet reported, Not yet reported Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections 32 participants Est. completion 2018-02-01 10 sites Stand-alone
    Other conditions: HIV-1 Infection
    View official trial listing →
  • Completed NCT NCT02441543

    Regulation of Lymphocyte Anti-tumor Response in Metastatic Patients Treated With the mTOR Inhibitor Everolimus

    Istituto Clinico Humanitas 45 participants Est. completion 2018-05 1 site
    Other conditions: SOLID TUMOR
    View official trial listing →
  • Completed NCT NCT02443818

    Sirolimus Effect on Hypertrophic Syndromes Related Gene PIK3CA

    Not yet reported Centre Hospitalier Universitaire Dijon 16 participants Est. completion 2016-11 11 sites
    Other conditions: Segmental Overgrowth Disorders Due to PIK3CA
    View official trial listing →
  • Completed NCT NCT02444390

    Molecular Alterations Associated With Resistance to Endocrine Therapy and Impacting Treatment With mTOR Inhibitor

    Not yet reported UNICANCER 150 participants Est. completion 2022-07-01 12 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT02448524

    Clinical Trial on the Efficacy and Safety of Sirolimus-Eluting Stent (MiStent® System)

    Not yet reported Micell Technologies 428 participants Est. completion 2022-11 16 sites Stand-alone
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT02449538

    Study to Evaluate the Safety and Efficacy of Everolimus, in Subjects With PIK3CA Amplification, PTEN Loss and PIK3CA Mutation Refractory Solid Tumors

    Not yet reported Samsung Medical Center 10 participants Est. completion 2016-08 1 site
    Other conditions: Solid Tumor
    View official trial listing →
  • Completed NCT NCT02449564

    The Pilot Study Evaluate the Safety and Efficacy of Sirolimus in Patients With PIK3CA Mutation and/or PIK3CA Amplification Refractory Solid Tumors

    Not yet reported Samsung Medical Center 5 participants Est. completion 2017-11-03 1 site Stand-alone
    Other conditions: Solid Tumor
    View official trial listing →
  • Status unknown NCT NCT02450175

    Etiology of the Platelet-Cancer Metastatic Pathway - A Study of Inflammatory Markers, Platelet Characteristics and Metastatic Surrogates in Cancer Patients and Controls

    Not yet reported Sinai Hospital of Baltimore 50 participants Est. completion 2016-06 1 site
    Other conditions: Neoplasm
    View official trial listing →
  • Completed NCT NCT02451696

    A Pilot Study To Evaluate The Effects of Everolimus on Brain mTOR Activity and Cortical Hyperexcitability in TSC and FCD

    Not yet reported NYU Langone Health 15 participants Est. completion 2017-12-28 1 site
    Other conditions: Epilepsy, Tuberous Sclerosis Complex, Focal Cortical Dysplasia
    View official trial listing →
  • Completed NCT NCT02454478

    Study of Lenvatinib in Combination With Everolimus in Participants With Unresectable Advanced or Metastatic Renal Cell Carcinoma (RCC)

    Not yet reported Eisai Co., Ltd. 7 participants Est. completion 2017-05-29 3 sites
    Other conditions: Carcinoma, Renal Cell
    View official trial listing →
  • Completed NCT NCT02456857

    Liposomal Doxorubicin, Bevacizumab, and Everolimus in Patients With Locally Advanced TNBC With Tumors Predicted Insensitive to Standard Chemotherapy; A Moonshot Initiative

    Not yet reported M.D. Anderson Cancer Center 17 participants Est. completion 2023-05-24 1 site
    Other conditions: Invasive Breast Carcinoma, Triple-Negative Breast Carcinoma
    View official trial listing →
  • Terminated NCT NCT02479490

    PRednisone Plus EVerolimus in Patients With Metastatic Renal Cell Cancer After Failure of VEGFR -TKI

    Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 8 participants Est. completion 2017-09 4 sites
    Other conditions: Metastatic Renal Cancer
    View official trial listing →
  • Completed NCT NCT02481453

    Rapamycine vs Placebo for the Treatment of Inclusion Body Myositis

    Not yet reported, Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 44 participants Est. completion 2018-01-22 1 site
    Other conditions: Inclusion Body Myositis (IBM)
    View official trial listing →
  • Completed NCT NCT02482974

    Conversion From Sirolimus to Everolimus in the Maintenance Treatment of Liver Transplant Recipients

    Ege University 66 participants Est. completion 2016-07 1 site
    Other conditions: Liver Transplant Recipients
    View official trial listing →
  • Completed NCT NCT02484664

    COLA: A Pilot Clinical Trial of COX-2 Inhibition in LAM and TSC

    Not yet reported Brigham and Women's Hospital 12 participants Est. completion 2018-11-19 1 site
    Other conditions: Lymphangioleiomyomatosis (LAM)
    View official trial listing →
  • Completed NCT NCT02486315

    Treatment of Coronary ARtery bIfurcation Narrowing by AXxess Stent Implantation

    Clinica Mediterranea 326 participants Est. completion 2015-06
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02487485

    Examining the Impact of Sirolimus on Ketamine's Antidepressant Effects

    Not yet reported Yale University 23 participants Est. completion 2020-01 2 sites Stand-alone
    Other conditions: Depression
    View official trial listing →
  • Status unknown NCT NCT02493465

    Effects of Everolimus in Left Ventricular Hypertrophy After Conversion From Azathioprine: A Pilot Study

    Not yet reported Instituto de Urologia e Nefrologia 50 participants Est. completion 2017-07 1 site
    Other conditions: Left Ventricular Hypertrophy
    View official trial listing →
  • Completed NCT NCT02494570

    A Phase 2 Study of Nab-sirolimus (ABI-009) in Patients With Advanced Malignant PEComa

    Not yet reported Aadi Bioscience, Inc. 34 participants Est. completion 2022-04 9 sites Stand-alone
    Other conditions: Malignant PEComa
    View official trial listing →
  • Status unknown NCT NCT02494895

    Ticagrelor Monotherapy After 3 Months in the Patients Treated With New Generation Sirolimus Stent for Acute Coronary Syndrome (TICO Study)

    Not yet reported Yonsei University 3056 participants Est. completion 2023-05 1 site
    Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Status unknown NCT NCT02496169

    Prospective multicEntric NonranDomized Registry

    Not yet reported Eucatech AG 400 participants Est. completion 2017-12
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02502851

    The Comparison of Strategies to PREPARE Severely CALCified Coronary Lesions Trial (PREPARE-CALC)

    Not yet reported Segeberger Kliniken GmbH 200 participants Est. completion 2019-10 1 site
    Other conditions: Coronary Atherosclerosis Due to Severely Calcified Coronary Lesion
    View official trial listing →
  • Completed NCT NCT02504307

    OCT Evaluation 3 Months After Sirolimus Eluting Stent Implantation

    Not yet reported Scitech Produtos Medicos SA 36 participants Est. completion 2017-09 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT02504892

    Everolimus Therapy in People With Birt-Hogg-Dube Syndrome (BHD)-Associated Kidney Cancer or Sporadic Chromophobe Renal Cancer

    Not yet reported National Cancer Institute (NCI) 3 participants Est. completion 2018-04-17 1 site
    Other conditions: Renal Cancer, Birt-Hogg-Dube Syndrome
    View official trial listing →
  • Completed NCT NCT02505893

    Minimal Islet Transplant at Diabetes Onset

    Not yet reported Ospedale San Raffaele 6 participants Est. completion 2023-12 1 site
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Status unknown NCT NCT02508714

    Bioresorbable Polymer ORSIRO Versus Durable Polymer RESOLUTE ONYX Stents

    Not yet reported Thorax Centrum Twente 2470 participants Est. completion 2019-03 7 sites
    Cardiovascular disease Other conditions: Angina Pectoris, Unstable Angina Pectoris, Acute Coronary Syndrome, Coronary Stenosis, Coronary Restenosis
    View official trial listing →
  • Completed NCT NCT02509468

    suPERficial Slow-flow Vascular malFORMations Treated With sirolimUS

    Not yet reported University Hospital, Tours 63 participants Est. completion 2019-03 12 sites Stand-alone
    Other conditions: Vascular Malformation
    View official trial listing →
  • Completed NCT NCT02511639

    Maintenance Aromatase Inhibitors (AIs)+ Everolimus vs AIs in Hormone Receptor Positive Metastatic Breast Cancer Patients

    Not yet reported Istituto Oncologico Veneto IRCCS 110 participants Est. completion 2020-07-31 16 sites
    Other conditions: Breast Cancer Metastatic
    View official trial listing →
  • Completed NCT NCT02512003

    Pilot Study of the Fantom Bioresorbable Scaffold (FANTOM I)

    Not yet reported REVA Medical, Inc. 7 participants Est. completion 2020-04 2 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02513303

    Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes

    Not yet reported Vascular Therapies, Inc. 269 participants Est. completion 2021-06 4 sites Stand-alone
    Other conditions: Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD, Chronic Kidney Failure, Complication of Hemodialysis, Vascular Access Complication, Arteriovenous Fistula
    View official trial listing →
  • Completed NCT NCT02514824

    MLN0128 in Recurrent/Metastatic Merkel Cell Carcinoma

    Not yet reported, Not yet reported Dana-Farber Cancer Institute 9 participants Est. completion 2017-06 1 site
    Other conditions: Merkel Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT02517918

    Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma

    Not yet reported Institut Bergonié 23 participants Est. completion 2021-11-16 3 sites Stand-alone
    Obstructive sleep apnea Other conditions: Solid Tumor
    View official trial listing →
  • Completed NCT NCT02520063

    Combination of Letrozole, Everolimus and TRC105 in Postmenopausal Women With Hormone-Receptor Positive and Her2 Negative Breast Cancer

    Not yet reported, Not yet reported University of Alabama at Birmingham 15 participants Est. completion 2022-12-01 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT02520180

    Non-inferiority Study Comparing Firehawk Stent With Abbott Xience Family Stent (TARGET-AC)

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 1653 participants Est. completion 2022-06 1 site
    Cardiovascular disease
    View official trial listing →
  • Withdrawn NCT NCT02524639

    Sirolimus for the Treatment of Hyperinsulinism

    Not yet reported, Not yet reported Children's Hospital of Philadelphia Est. completion 2018-05-29 1 site Stand-alone
    Other conditions: Hyperinsulinism
    View official trial listing →
  • Withdrawn NCT NCT02528877

    Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis

    Not yet reported City of Hope Medical Center 1 site Stand-alone
    Other conditions: Acute Myeloid Leukemia in Remission, Primary Myelofibrosis, Primary Myelofibrosis, Prefibrotic Stage, Secondary Acute Myeloid Leukemia, Secondary Myelofibrosis
    View official trial listing →
  • Completed NCT NCT02531932

    Comparison of Single-Agent Carboplatin vs the Combination of Carboplatin and Everolimus for the Treatment of Advanced Triple-Negative Breast Cancer

    Not yet reported Amy Tiersten 64 participants Est. completion 2024-10-19 3 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT02539459

    Sporadic Angiomyolipomas (AMLs) Growth Kinetics While on Everolimus

    Not yet reported Fox Chase Cancer Center 20 participants Est. completion 2018-08-20 8 sites
    Other conditions: Sporadic Angiomyolipomas (AMLs)
    View official trial listing →
  • Completed NCT NCT02539966

    Safety & Performance Study of the FANTOM Sirolimus-Eluting Bioresorbable Coronary Scaffold

    Not yet reported REVA Medical, Inc. 272 participants Est. completion 2024-09 28 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02542007

    Safety and Efficacy of the Combo Bio-engineered Sirolimus-eluting Stent Versus the Nano Polymer-free Sirolimus-eluting Stent in the Treatment of Patients With de Novo Stenotic Lesions

    Not yet reported OrbusNeich 440 participants Est. completion 2021-06-10 15 sites Stand-alone
    Other conditions: Coronary Arteriosclerosis
    View official trial listing →
  • Completed NCT NCT02545985

    First-in-man Sirolimus-eluting Prolim® Stent Registry

    Not yet reported Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland 204 participants Est. completion 2015-06
    Other conditions: Sirolimus-eluting Stainless Steel Coronary Stent Prolim®
    View official trial listing →
  • Completed NCT NCT02551718

    High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia

    Not yet reported University of Washington 34 participants Est. completion 2021-05-13 1 site
    Other conditions: Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Acute Leukemia of Ambiguous Lineage
    View official trial listing →
  • Completed NCT NCT02554955

    A Study of Daclizumab (Zenapax) in Combination With Mycophenolate Mofetil (CellCept) and Sirolimus in Prevention of Acute Rejection in Heart Transplant Participants

    Not yet reported Hoffmann-La Roche 36 participants Est. completion 2007-12 14 sites Stand-alone
    Other conditions: Heart Transplantation
    View official trial listing →
  • Terminated NCT NCT02560012

    Personalized Targeted Inhibitors Treatment in Renal Cell Cancer

    Not yet reported The University of Texas Health Science Center, Houston 4 participants Est. completion 2017-07-27 1 site
    Other conditions: Carcinoma, Renal Cell
    View official trial listing →
  • Terminated NCT NCT02565901

    Sirolimus, Docetaxel, and Carboplatin in Treating Patients With Metastatic Castration-Resistant Prostate Cancer

    Not yet reported, Not yet reported University of Washington 28 participants Est. completion 2020-06-16 1 site Stand-alone
    Other conditions: Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IV Prostate Cancer AJCC v7, Metastatic Malignant Neoplasm in the Bone
    View official trial listing →
  • Active, not recruiting NCT NCT02567435

    Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

    Not yet reported National Cancer Institute (NCI) 325 participants Est. completion 2026-10-27 382 sites
    Obstructive sleep apnea
    View official trial listing →
  • Withdrawn NCT NCT02569125

    Open Label Study of Everolimus (RAD001) in Patients With Segmental Overgrowth Syndrome

    Not yet reported Jochen Roessler Est. completion 2016-02 4 sites
    Other conditions: Segmental Overgrowth Syndrome
    View official trial listing →
  • Status unknown NCT NCT02577458

    Study of the Combination of CM082 With Everolimus in Patients With mRCC

    Not yet reported AnewPharma 18 participants Est. completion 2018-06 1 site
    Other conditions: Renal Cell Carcinoma Recurrent
    View official trial listing →
  • Completed NCT NCT02578069

    First-in-man Trial Evaluating the Safety and Efficacy of the NOVA Intracranial Stent (NOVA Trial)

    Not yet reported Sino Medical Sciences Technology Inc. 272 participants Est. completion 2020-01 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02579031

    A Comparison of an Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent With a Durable Polymer Everolimus-Eluting Stent for Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

    Not yet reported Insel Gruppe AG, University Hospital Bern 1300 participants Est. completion 2020-05 10 sites
    Cardiovascular disease Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Enrolling by invitation NCT NCT02579044

    Phase I/II Trial of Everolimus in Combination With Lonafarnib in Progeria

    Not yet reported, Not yet reported Boston Children's Hospital 80 participants Est. completion 2027-03 1 site
    Other conditions: Progeria
    View official trial listing →
  • Status unknown NCT NCT02583542

    A Study of AZD2014 in Combination With Selumetinib in Patients With Advanced Cancers

    Not yet reported, Not yet reported Queen Mary University of London 118 participants Est. completion 2020-03 4 sites
    Other conditions: Triple-Negative Breast Cancer, Squamous Cell Lung Cancer, Non-squamous Cell Lung Cancer With KRAS Mutations, Non-squamous Cell Lung Cancer With Wild-type KRAS
    View official trial listing →
  • Completed NCT NCT02583893

    Biomarkers in Predicting Treatment Response to Sirolimus and Chemotherapy in Patients With High-Risk Acute Myeloid Leukemia

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 39 participants Est. completion 2023-05-17 1 site Stand-alone
    Other conditions: Recurrent Adult Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Untreated Adult Acute Myeloid Leukemia
    View official trial listing →
  • Terminated NCT NCT02584647

    PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors

    Not yet reported, Not yet reported Gulam Manji 39 participants Est. completion 2024-10-01 5 sites Stand-alone
    Other conditions: Sarcoma, Malignant Peripheral Nerve Sheath Tumors
    View official trial listing →
  • Completed NCT NCT02587325

    Phase 1/1b Study With Nab-sirolimus for Patients With Severe Pulmonary Arterial Hypertension

    Not yet reported Aadi Bioscience, Inc. 15 participants Est. completion 2022-09-16 6 sites Stand-alone
    Other conditions: Pulmonary Hypertension
    View official trial listing →
  • Completed NCT NCT02588339

    Panobinostat (LBH589): Acute Graft Versus Host Disease (aGVHD) Prevention

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 42 participants Est. completion 2021-07-13 1 site Stand-alone
    Other conditions: Graft Versus Host Disease, GVHD
    View official trial listing →
  • Completed NCT NCT02596828

    Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade Pineoblastoma

    Not yet reported University of Regensburg 4 participants Est. completion 2021-04 1 site
    Other conditions: Pineoblastoma
    View official trial listing →
  • Withdrawn NCT NCT02597283

    Coronary Bifurcation Lesions Treated With Biguard Stent System

    Not yet reported Nanjing First Hospital, Nanjing Medical University Est. completion 2015-12 Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02599324

    Study to Evaluate Ibrutinib Combination Therapy in Patients With Selected Gastrointestinal and Genitourinary Tumors

    Not yet reported, Not yet reported Pharmacyclics LLC. 263 participants Est. completion 2021-08-20 65 sites
    Other conditions: Metastatic Renal Cell Carcinoma, Advanced Urothelial Carcinoma, Advanced Gastric Adenocarcinoma, Metastatic Colorectal Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT02601157

    Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial

    Not yet reported Seoul National University Hospital 2173 participants Est. completion 2022-08-14 12 sites Stand-alone
    Cardiovascular disease Other conditions: Stable Angina, Unstable Angina
    View official trial listing →
  • Status unknown NCT NCT02616848

    Safety and Tolerability of Everolimus in Combination With Eribulin in Triple-negative Breast Cancers

    Not yet reported Istituti Ospitalieri di Cremona 1 participants 1 site
    Other conditions: Triple Negative Breast Cancer
    View official trial listing →
  • Withdrawn NCT NCT02619669

    Neoadjuvant Run-In Study With TAK-228 Followed by Letrozole/TAK-228 in Women With High-Risk ER+/HER2- Breast Cancer

    Not yet reported Gary Schwartz Est. completion 2019-06-14 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT02623140

    BIOFREEDOM Stent Versus ORSIRO Stent: SORT OUT IX

    Not yet reported Odense University Hospital 3150 participants Est. completion 2023-10 1 site
    Other conditions: Ischaemic Heart Disease
    View official trial listing →
  • Active, not recruiting NCT NCT02629120

    High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 45 participants Est. completion 2028-12-30 1 site
    Other conditions: Chronic Granulomatous Disease Transplant
    View official trial listing →
  • Completed NCT NCT02629575

    Coroflex ISAR 2000 Registry

    B. Braun Melsungen AG 2877 participants Est. completion 2017-12 3 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02634931

    Long-term Trial of Topical Sirolimus to Angiofibroma in Patient With Tuberous Sclerosis Complex

    Not yet reported Nobelpharma 94 participants Est. completion 2018-10 1 site Stand-alone
    Other conditions: Tuberous Sclerosis, Angiofibroma, Hypomelanotic Macule, Plaque
    View official trial listing →
  • Completed NCT NCT02635789

    Phase III Trial of Topical Formulation of Sirolimus to Skin Lesions in Patients With Tuberous Sclerosis Complex (TSC)

    Not yet reported Nobelpharma 62 participants Est. completion 2016-10 1 site Stand-alone
    Other conditions: Tuberous Sclerosis, Angiofibroma, Hypomelanotic Macule, Plaque
    View official trial listing →
  • Status unknown NCT NCT02638428

    Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy

    Not yet reported Samsung Medical Center 90 participants Est. completion 2023-12 1 site
    Other conditions: Relapsed Pediatric Solid Tumor, Refractory Pediatric Solid Tumor, Relapsed Pediatric AML, Refractory Pediatric AML
    View official trial listing →
  • Terminated NCT NCT02642094

    Aging Mammary Stem Cells and Breast Cancer Prevention

    Not yet reported LuZhe Sun 58 participants Est. completion 2022-05-01 1 site
    Other conditions: Cancer of Breast
    View official trial listing →
  • Completed NCT NCT02646319

    Nanoparticle Albumin-Bound Rapamycin in Treating Patients With Advanced Cancer With mTOR Mutations

    Not yet reported Mayo Clinic 2 participants Est. completion 2018-04-24 2 sites
    Other conditions: Advanced Malignant Neoplasm, Cervical Squamous Cell Carcinoma, Endometrial Carcinoma, Malignant Uterine Neoplasm, Recurrent Bladder Carcinoma, Recurrent Breast Carcinoma, Recurrent Cervical Carcinoma, Recurrent Head and Neck Carcinoma, Recurrent Malignant Neoplasm, Recurrent Ovarian Carcinoma, Recurrent Prostate Carcinoma, Recurrent Renal Cell Carcinoma, Solid Neoplasm, Stage III Bladder Cancer, Stage III Prostate Cancer, Stage III Renal Cell Cancer, Stage IIIA Breast Cancer, Stage IIIA Cervical Cancer, Stage IIIA Ovarian Cancer, Stage IIIB Breast Cancer, Stage IIIB Cervical Cancer, Stage IIIB Ovarian Cancer, Stage IIIC Breast Cancer, Stage IIIC Ovarian Cancer, Stage IV Breast Cancer, Stage IV Ovarian Cancer, Stage IV Prostate Cancer, Stage IV Renal Cell Cancer, Stage IVA Bladder Cancer, Stage IVA Cervical Cancer, Stage IVB Bladder Cancer, Stage IVB Cervical Cancer
    View official trial listing →
  • Completed NCT NCT02659254

    A First-in-Man Study of the Firesorb BVS (FUTURE-I)

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 45 participants Est. completion 2021-03 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT02663323

    Pilot Clinical Study of MeRes100 Sirolimus Eluting Bioresorbable Vascular Scaffold System

    Not yet reported Meril Life Sciences Pvt. Ltd. 64 participants Est. completion 2020-07-05 4 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02669511

    PQR309 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma

    Not yet reported PIQUR Therapeutics AG 21 participants Est. completion 2018-01-12
    Other conditions: Primary Central Nervous System Lymphoma
    View official trial listing →
  • Status unknown NCT NCT02671318

    Conversion to Sirolimus: Effects in Cytomegalovirus Infection Recurrence

    Not yet reported Hospital do Rim e Hipertensão 250 participants Est. completion 2020-08 1 site
    Other conditions: Cytomegalovirus Infections
    View official trial listing →
  • Status unknown NCT NCT02675153

    To Evaluate the Efficacy and Safety of Rapamycin for Crohn's Disease-related Stricture

    Not yet reported The Second Hospital of Nanjing Medical University 15 participants Est. completion 2020-10 1 site Stand-alone
    Other conditions: Crohn's Diseases
    View official trial listing →
  • Terminated NCT NCT02678143

    Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease

    Not yet reported Washington University School of Medicine 1 participants Est. completion 2021-11-16 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Completed NCT NCT02681016

    Sirolimus-eluting Stent CALYPSO vs Everolimus-eluting Stent XIENCE

    Not yet reported Meshalkin Research Institute of Pathology of Circulation 610 participants Est. completion 2017-07 1 site Stand-alone
    Cardiovascular disease Other conditions: Ischemic Heart Disease, Coronary Atherosclerosis, Coronary Artery Stenosis
    View official trial listing →
  • Completed NCT NCT02683291

    Sirolimus Associated With Tacrolimus at Low Doses in Elderly Kidney Transplant Patients

    Not yet reported Associação Médico Espírita de Botucatu 48 participants Est. completion 2016-01 Stand-alone
    Other conditions: Disorder Related to Renal Transplantation, Cytomegalovirus Infections
    View official trial listing →
  • Completed NCT NCT02684032

    A Study To Assess The Tolerability And Clinical Activity Of Gedatolisib In Combination With Palbociclib/Letrozole Or Palbociclib/Fulvestrant In Women With Metastatic Breast Cancer

    Not yet reported Celcuity Inc 141 participants Est. completion 2022-01-19 41 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT02686619

    Study Comparing Efficacy and Safety of Mycophenolate Mofetil (Cellcept) With Delayed Introduction of Sirolimus and Discontinuation of Cyclosporine, With Those of Mycophenolate Mofetil and Long Term Continuation of Cyclosporine in Renal Transplant Recipients

    Not yet reported Hoffmann-La Roche 237 participants Est. completion 2011-01 17 sites Stand-alone
    Other conditions: Renal Transplantation
    View official trial listing →
  • Status unknown NCT NCT02687958

    Study of Everolimus as Maintenance Therapy for Metastatic NEC With Pulmonary or Gastroenteropancreatic Origin

    Not yet reported Gruppo Oncologico Italiano di Ricerca Clinica 30 participants Est. completion 2023-12 5 sites
    Other conditions: Neuroendocrine Carcinoma
    View official trial listing →
  • Completed NCT NCT02688829

    The First-In-Man Pilot Study of Firehawk

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 21 participants Est. completion 2015-01
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT02688842

    Evaluation of New Specifications (38mm) of FirehawkTM in the Treatment of Coronary Heart Disease

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 38 participants Est. completion 2021-01 1 site
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT02688868

    Evaluation of New Specifications (2.25mm) of FirehawkTM in the Treatment of Coronary Heart Disease ( Firehawk_2.25 )

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 38 participants Est. completion 2020-12 1 site
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT02688881

    Study to Evaluate the Safety and Efficacy of Sirolimus, in Subject With Refractory Solid Tumors

    Not yet reported Samsung Medical Center 6 participants Est. completion 2021-02-24 1 site Stand-alone
    Other conditions: Refractory Solid Tumors
    View official trial listing →
  • Completed NCT NCT02693158

    The Direct III Post Market Study

    Svelte Medical Systems, Inc. 440 participants Est. completion 2020-01 8 sites
    Cardiovascular disease
    View official trial listing →
  • Withdrawn NCT NCT02694770

    A Study Evaluating the Efficacy and Safety of Neihulizumab vs "Conventional Treatment" to Treat Sr-aGvHD

    Not yet reported AbGenomics B.V Taiwan Branch Est. completion 2018-02 2 sites
    Other conditions: Steroid-refractory aGvHD Subsequent to Allogeneic Hematopoietic Cell Transplantation
    View official trial listing →
  • Status unknown NCT NCT02695459

    Cisplatinum and Everolimus in Patients With Metastatic or Unresectable NEC of Extrapulmonary Origin

    Not yet reported The Netherlands Cancer Institute 39 participants Est. completion 2021-08 3 sites
    Other conditions: Neuroendocrine Carcinomas
    View official trial listing →
  • Status unknown NCT NCT02698839

    A Study to Evaluate the Efficacy and Safety of BuMA Supreme Drug Eluting Stent(DES)

    Not yet reported Sino Medical Sciences Technology Inc. 539 participants Est. completion 2025-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT02698852

    A Study to Evaluate the Efficacy and Safety of BuMA Supreme Drug Eluting Stent(DES)

    Not yet reported Sino Medical Sciences Technology Inc. 1000 participants Est. completion 2025-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02711202

    Sequential Targeting of Cluster of Differentiation 52 (CD52) and Tumor Necrosis Factor (TNF) Allows Early Minimization Therapy in Kidney Transplantation

    Not yet reported Institute for Clinical and Experimental Medicine 20 participants Est. completion 2009-03
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT02711826

    Treg Therapy in Subclinical Inflammation in Kidney Transplantation

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 32 participants Est. completion 2023-08-04 6 sites
    Other conditions: Kidney Transplant, Adult Living Donor Kidney Transplant Recipients, Renal Transplant, Living Kidney Donor
    View official trial listing →
  • Completed NCT NCT02722668

    UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep

    Not yet reported Masonic Cancer Center, University of Minnesota 15 participants Est. completion 2024-02-22 1 site Stand-alone
    Other conditions: Acute Leukemia, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia/Lymphoma, Burkitt's Lymphoma, Natural Killer Cell Malignancies, Chronic Myelogenous Leukemia, Myelodysplastic Syndrome, Large-cell Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Relapsed Chronic Lymphocytic Leukemia, Relapsed Small Lymphocytic Lymphoma, Marginal Zone B-cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-cell Lymphoma, Prolymphocytic Leukemia, Bone Marrow Failure Syndromes, Myeloproliferative Neoplasms/Myelofibrosis, Biphenotypic/Undifferentiated/Prolymphocytic Leukemias, MRD Positive Leukemia, Leukemia or MDS in Aplasia, Relapsed T-Cell Lymphoma, Relapsed Multiple Myeloma, Plasma Cell Leukemia
    View official trial listing →
  • Completed NCT NCT02723877

    PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)

    Not yet reported, Not yet reported PIQUR Therapeutics AG 41 participants Est. completion 2018-10-03 5 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Withdrawn NCT NCT02723981

    COMBO-Stent in Patients on Chronic Anticoagulant Therapy (COSTA) COSTA-Bleed and COSTA-Outcome Trials

    Not yet reported IHF GmbH - Institut für Herzinfarktforschung Est. completion 2018-12 10 sites Stand-alone
    Other conditions: Stable Angina, Unstable Angina, STEMI, NSTEMI, Coronary Disease
    View official trial listing →
  • Completed NCT NCT02724020

    MLN0128 and MLN0128 + MLN1117 Compared With Everolimus in the Treatment of Adults With Advanced or Metastatic Clear-Cell Renal Cell Carcinoma

    Not yet reported Millennium Pharmaceuticals, Inc. 96 participants Est. completion 2020-10-13 36 sites
    Other conditions: Clear-cell Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT02724332

    Adjuvant Anti-Recurrence Treatment With Rapamycin on Early-stage HCC

    Not yet reported Eastern Hepatobiliary Surgery Hospital 300 participants Est. completion 2015-12 1 site
    Other conditions: Hepatocellular Carcinoma, Rapamycin
    View official trial listing →
  • Terminated NCT NCT02728700

    Sirolimus and Mycophenolate Mofetil in Preventing GVHD in Patients With Hematologic Malignancies Undergoing HSCT

    Not yet reported Stanford University 1 participants Est. completion 2018-07 1 site Stand-alone
    Other conditions: Adult Hodgkin Lymphoma, Adult Myelodysplastic Syndrome, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Hodgkin Lymphoma, Childhood Myelodysplastic Syndrome, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Myelofibrosis, Primary Myelofibrosis, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Non-Hodgkin Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Non-Hodgkin Lymphoma, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Non-Hodgkin Lymphoma
    View official trial listing →
  • Status unknown NCT NCT02730923

    Hormone Receptor Positive endometrIal Carcinoma Treated by Dual mTORC1/mTORC2 Inhibitor and Anastrozole (VICTORIA)

    Not yet reported, Not yet reported Centre Leon Berard 72 participants Est. completion 2024-12 12 sites
    Other conditions: Endometrial Carcinoma, Metastatic Carcinoma, Hormone Receptor Positive Tumor
    View official trial listing →
  • Completed NCT NCT02732119

    Study of Ribociclib With Everolimus + Exemestane in HR+ HER2- Locally Advanced/Metastatic Breast Cancer Post Progression on CDK 4/6 Inhibitor.

    Not yet reported, Not yet reported Novartis Pharmaceuticals 104 participants Est. completion 2020-02-25 25 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT02732899

    Sirolimus in Conjunction With Eylea vs Eylea Alone for Exudative AMD

    Not yet reported Maturi, Raj K., M.D., P.C. 20 participants Est. completion 2017-04-04 1 site Stand-alone
    Other conditions: Exudative Age Related Macular Degeneration
    View official trial listing →
  • Completed NCT NCT02742051

    A Trial of Neoadjuvant Everolimus Plus Letrozole Versus FEC in Women With ER-positive, HER2-negative Breast Cancer

    Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 40 participants Est. completion 2020-03-14 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT02753309

    A Study of Rapamycin Combined With Intravesical BCG in Patients With Non-muscle Invasive Bladder Cancer

    Not yet reported The University of Texas Health Science Center at San Antonio 33 participants Est. completion 2021-03-02 1 site
    Other conditions: Bladder Cancer
    View official trial listing →
  • Completed NCT NCT02756572

    Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms

    Not yet reported University of Washington 30 participants Est. completion 2020-07-01 1 site Stand-alone
    Other conditions: Blasts 10 Percent or More of Bone Marrow Nucleated Cells, Chronic Myelomonocytic Leukemia-2, High Grade Malignant Neoplasm, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts-2, Myeloid Neoplasm, Previously Treated Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia
    View official trial listing →
  • Completed NCT NCT02766465

    Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)

    Not yet reported Medical College of Wisconsin 138 participants Est. completion 2023-08-02 35 sites Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Status unknown NCT NCT02768116

    The Study of Active Transfer of Plaque Technique for Non-Left Main Coronary Bifurcation Lesions

    Not yet reported Beijing Anzhen Hospital 316 participants Est. completion 2021-12 Stand-alone
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Status unknown NCT NCT02776202

    HLA-Identical Sibling Donor Bone Marrow Transplantation for Individuals With Severe Sickle Cell Disease Using a Reduced Intensity Conditioning Regimen

    Not yet reported National Guard Health Affairs 15 participants Est. completion 2019-12 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Completed NCT NCT02776644

    Clinical Outcome Of Advanced Renal Cell Carcinoma In Taiwan

    Pfizer 1349 participants Est. completion 2017-12-30
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT02788201

    Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma

    Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2019-10-23 1 site
    Other conditions: Urothelial Carcinoma, Bladder Cancer, Urinary Bladder Neoplasms
    View official trial listing →
  • Active, not recruiting NCT NCT02790515

    Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation

    Not yet reported St. Jude Children's Research Hospital 170 participants Est. completion 2026-07-01 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Myeloid Sarcoma, Chronic Myeloid Leukemia (CML), Juvenile Myelomonocytic Leukemia (JMML), Myelodysplastic Syndrome (MDS), Non-Hodgkin Lymphoma (NHL)
    View official trial listing →
  • Completed NCT NCT02793544

    HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide

    Not yet reported Center for International Blood and Marrow Transplant Research 80 participants Est. completion 2020-03 11 sites
    Other conditions: Myelodysplastic Syndrome (MDS), Chronic Lymphocytic Leukemia (CLL), Chemotherapy-sensitive Lymphoma, Acute Lymphoblastic Leukemia (ALL)/T Lymphoblastic Lymphoma, Acute Myelogenous Leukemia (AML), Acute Biphenotypic Leukemia (ABL), Acute Undifferentiated Leukemia (AUL)
    View official trial listing →
  • Completed NCT NCT02796898

    Study of the Efficacy, Safety, and Pharmacokinetics of SM88 in Patients With Prostate Cancer

    Not yet reported, Not yet reported Tyme, Inc 23 participants Est. completion 2019-05-30 5 sites Stand-alone
    Other conditions: Prostate Cancer, Rising Prostate Specific Antigen (PSA)
    View official trial listing →
  • Status unknown NCT NCT02802644

    The Effect of DPP4 Inhibitor on Vasclular Healing

    Not yet reported Chung-Ang University 66 participants 6 sites
    Type 2 diabetes Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Completed NCT NCT02803892

    Monotherapy With Rapamycin in Long-standing Type 1 Diabetes

    Not yet reported Piemonti Lorenzo 55 participants Est. completion 2019-03 1 site
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT02806947

    A Study to Evaluate Steroid-free Treatment for Standard-Risk aGVHD (BMT CTN 1501)

    Not yet reported Medical College of Wisconsin 127 participants Est. completion 2019-02-19 21 sites Stand-alone
    Other conditions: Acute GVHD
    View official trial listing →
  • Completed NCT NCT02809404

    Dried Blood SPOT Analysis of Everolimus in Cancer Patients (SPOT-study)

    Radboud University Medical Center 75 participants Est. completion 2017-01 1 site
    Other conditions: Breast Cancer, Renal Cell Carcinoma
    View official trial listing →
  • Active, not recruiting NCT NCT02811861

    Lenvatinib/Everolimus or Lenvatinib/Pembrolizumab Versus Sunitinib Alone as Treatment of Advanced Renal Cell Carcinoma

    Not yet reported Eisai Inc. 1069 participants Est. completion 2027-03-31 183 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT02812940

    Single-centre Study of Everolimus as GvHD Prophylaxis After Post-Transplantation Cyclophosphamide After Allogeneic SCT

    Not yet reported University of Cologne 19 participants Est. completion 2020-12 1 site
    Other conditions: Graft-versus-Host Disease
    View official trial listing →
  • Status unknown NCT NCT02817802

    BIOTRONIKS - Safety and Performance in de NOvo Lesion of NatiVE Coronary Arteries With Magmaris- Registry: BIOSOLVE-IV

    Biotronik AG 2066 participants Est. completion 2025-10 2 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02821026

    Omental Islet Transplant

    Not yet reported, Not yet reported University of Alberta 4 participants Est. completion 2019-11-13 1 site Stand-alone
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT02821507

    Sirolimus and Cyclophosphamide in Metastatic or Unresectable Myxoid Liposarcoma and Chondrosarcoma

    Not yet reported Leiden University Medical Center 70 participants Est. completion 2021-12 7 sites Stand-alone
    Obstructive sleep apnea
    View official trial listing →
  • Withdrawn NCT NCT02833506

    Sirolimus and Vaccine Therapy in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

    Not yet reported Roswell Park Cancer Institute Est. completion 2019-08-15 1 site Stand-alone
    Other conditions: Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal Carcinoma, Stage IIA Fallopian Tube Cancer, Stage IIA Ovarian Cancer, Stage IIB Fallopian Tube Cancer, Stage IIB Ovarian Cancer, Stage IIC Fallopian Tube Cancer, Stage IIC Ovarian Cancer, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Cancer, Stage IIIA Primary Peritoneal Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Cancer, Stage IIIB Primary Peritoneal Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Cancer, Stage IIIC Primary Peritoneal Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Cancer, Stage IV Primary Peritoneal Cancer
    View official trial listing →
  • Status unknown NCT NCT02836847

    Molecularly Target Therapy With GEMOX in Advanced or Recurrent Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

    Not yet reported Shanghai Jiao Tong University School of Medicine 152 participants Est. completion 2020-12 1 site
    Other conditions: Cholangiocarcinoma of the Extrahepatic Bile Duct, Gallbladder Cancer
    View official trial listing →
  • Status unknown NCT NCT02837003

    3-Month Discontinuation of Dual Antiplatelet Therapy After Ultimaster Sirolimus-Eluting Stent Implantation

    Teikyo University 1500 participants Est. completion 2019-03 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02842749

    Phase IV Study of the Safety and Efficacy of Everolimus in Adult Patients With Progressive pNET in China

    Not yet reported Novartis Pharmaceuticals 61 participants Est. completion 2024-02-22 5 sites
    Other conditions: Pancreatic Neuroendocrine Tumors
    View official trial listing →
  • Status unknown NCT NCT02844270

    Galaxy Rapamycin Drug-Eluting Bioresorbable Coronary Stent System First-in-man Study

    Not yet reported Shanghai Bio-heart Biological Technology Co., Ltd. 45 participants Est. completion 2021-12
    Other conditions: Heart Diseases
    View official trial listing →
  • Status unknown NCT NCT02853994

    Safety and Efficacy of the DEVOIR Sirolimus-Coated Coronary Balloon in the Real-world Clinical Practice

    MINVASYS 500 participants Est. completion 2018-09
    Other conditions: CAD
    View official trial listing →
  • Withdrawn NCT NCT02860494

    Topical Everolimus in Patients With Tuberous Sclerosis Complex

    Not yet reported, Not yet reported Hospices Civils de Lyon Est. completion 2024-12 1 site
    Other conditions: Facial Angiofibromas
    View official trial listing →
  • Completed NCT NCT02864706

    SCHEDULE Follow Up Visit 5-7 yr

    Not yet reported Novartis Pharmaceuticals 95 participants Est. completion 2017-09-25 6 sites
    Other conditions: Heart Transplantation
    View official trial listing →
  • Completed NCT NCT02867800

    Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease

    Not yet reported Monica Bhatia 24 participants Est. completion 2023-12-30 7 sites Stand-alone
    Other conditions: Sickle Cell Disease, Graft Versus Host Disease
    View official trial listing →
  • Status unknown NCT NCT02868203

    OCT Based Edge and In-stent Vascular Response After Cordimax Stent in patIents With NSTE-ACS

    Not yet reported Xijing Hospital 80 participants Est. completion 2020-08
    Cardiovascular disease Other conditions: Angina, Unstable
    View official trial listing →
  • Completed NCT NCT02869087

    The DESappear Study: Drug Eluting Scaffold

    Not yet reported Elixir Medical Corporation 21 participants Est. completion 2021-04-30 11 sites Stand-alone
    Other conditions: Peripheral Vascular Disease
    View official trial listing →
  • Completed NCT NCT02870140

    Thin Strut Sirolimus-eluting Stent in All Comers Population vs Everolimus-eluting Stent

    Not yet reported ECRI bv 1435 participants Est. completion 2020-08-26 23 sites Stand-alone
    Other conditions: Coronary Stenosis
    View official trial listing →
  • Completed NCT NCT02871791

    Palbociclib With Everolimus + Exemestane In BC

    Not yet reported, Not yet reported Dana-Farber Cancer Institute 41 participants Est. completion 2021-09 1 site
    Other conditions: Human Epidermal Growth Factor 2 Negative Carcinoma of Breast, Hormone Receptor (HR)-Positive Breast Cancer
    View official trial listing →
  • Completed NCT NCT02874924

    Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly

    Not yet reported The University of Texas Health Science Center at San Antonio 34 participants Est. completion 2018-09 1 site
    Other conditions: Aging
    View official trial listing →
  • Completed NCT NCT02890069

    A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat

    Not yet reported Novartis Pharmaceuticals 298 participants Est. completion 2022-02-22 25 sites
    Other conditions: Colorectal Cancer, Non-small Cell Lung Carcinoma (Adenocarcinoma), Triple Negative Breast Cancer, Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT02890160

    A Trial of Firesorb in Patients With Coronary Artery Disease: FUTURE-II

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 430 participants Est. completion 2024-10-03 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02891603

    A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression

    Not yet reported, Not yet reported H. Lee Moffitt Cancer Center and Research Institute 40 participants Est. completion 2022-04-18 2 sites Stand-alone
    Other conditions: Graft Vs Host Disease, GVHD
    View official trial listing →
  • Status unknown NCT NCT02901353

    A Prospective, Single-arm, Multi-centre, Observational, Real World Registry

    Meril Life Sciences Pvt. Ltd. 400 participants Est. completion 2022-12-01 5 sites
    Other conditions: Angina Pectoris
    View official trial listing →
  • Completed NCT NCT02905214

    Coroflex ISAR 2000 Extended Registry (ISAR2000 Extended)

    B. Braun Melsungen AG 4369 participants Est. completion 2021-12 3 sites
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT02908035

    Temsirolimus Adventitial Delivery to Improve Angiographic Outcomes Below the Knee (TANGO)

    Not yet reported Mercator MedSystems, Inc. 100 participants Est. completion 2021-09 8 sites
    Other conditions: Chronic Limb Ischemia
    View official trial listing →
  • Withdrawn NCT NCT02909335

    De Novo Everolimus Versus Tacrolimus in Combination With Mofetil Mycophenolate and Low Dose Corticosteroids to Reduce Tacrolimus Induced Nephrotoxicity in Liver Transplantation: a Prospective, Multicentric, Randomised Study

    Not yet reported Rennes University Hospital Est. completion 2021-11
    Other conditions: Liver Transplantation
    View official trial listing →
  • Completed NCT NCT02913261

    Safety and Efficacy of Ruxolitinib Versus Best Available Therapy in Patients With Corticosteroid-refractory Acute Graft vs. Host Disease After Allogeneic Stem Cell Transplantation

    Not yet reported Novartis Pharmaceuticals 310 participants Est. completion 2021-04-23 103 sites
    Other conditions: Corticosteroid Refractory Acute Graft vs Host Disease
    View official trial listing →
  • Status unknown NCT NCT02915107

    The SORT OUT IX STEMI OCT Trial

    Not yet reported Odense University Hospital 80 participants Est. completion 2023-09 3 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02915783

    A Trial to Evaluate Efficacy and Safety of Lenvatinib in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Non Clear Cell Renal Cell Carcinoma (nccRCC) Who Have Not Received Any Chemotherapy for Advanced Disease

    Not yet reported Eisai Inc. 41 participants Est. completion 2021-11-02 8 sites
    Other conditions: Non Clear Cell Renal Cell Carcinoma (nccRCC)
    View official trial listing →
  • Suspended NCT NCT02916485

    Safety and Clinical Performance of a Sirolimus-eluting Absorbable Metal Scaffold

    Not yet reported Biotronik AG 100 participants Est. completion 2018-09 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT02917096

    Ruxolitinib Phosphate and Chemotherapy Given Before and After Reduced Intensity Donor Stem Cell Transplant in Treating Patients With Myelofibrosis

    Not yet reported City of Hope Medical Center 18 participants Est. completion 2023-08-31 1 site Stand-alone
    Other conditions: Primary Myelofibrosis, Secondary Myelofibrosis
    View official trial listing →
  • Terminated NCT NCT02920450

    Study of Paclitaxel, Carboplatin, and PF-05212384 in Advanced or Metastatic NSCLC (UF-STO-LUNG-002)

    Not yet reported, Not yet reported University of Florida 3 participants Est. completion 2019-04-04 1 site
    Other conditions: Non-Small Cell Lung Cancer
    View official trial listing →
  • Status unknown NCT NCT02929030

    Clinical Performance of Nano Plus Sirolimus-Eluting Stents in Patients With Coronary Artery Disease

    Xijing Hospital 2500 participants Est. completion 2022-01 1 site
    Cardiovascular disease
    View official trial listing →
  • Withdrawn NCT NCT02939365

    Precision Medicine Offers Belatacept Monotherapy

    Not yet reported University of California, San Francisco Est. completion 2022-12
    Other conditions: Transplantation
    View official trial listing →
  • Completed NCT NCT02941224

    First-in-human Evaluation of the SELUTION DCB, a Novel Sirolimus Coated Balloon in Peripheral Arteries

    Not yet reported M.A. Med Alliance S.A. 50 participants Est. completion 2019-09 4 sites Stand-alone
    Other conditions: Patients With Peripheral Artery Disease in the SFA or PA
    View official trial listing →
  • Completed NCT NCT02954198

    Once-daily Regimen With Envarsus® to Optimize Immunosuppression Management and Outcomes in Kidney Transplant Recipients

    Not yet reported Medical University of South Carolina 40 participants Est. completion 2018-12-27 1 site
    Other conditions: Immunosuppression
    View official trial listing →
  • Completed NCT NCT02959918

    Multi-Dose Safety/Pharmacodynamic Study of SEL-212/SEL-037 in Subjects With Symptomatic Gout & Elevated Blood Uric Acid

    Not yet reported Selecta Biosciences, Inc. 152 participants Est. completion 2019-01 13 sites
    Other conditions: Gout Chronic, Hyperuricemia
    View official trial listing →
  • Completed NCT NCT02960997

    Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study

    Not yet reported Stanford University 8 participants Est. completion 2021-12-01 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Weber-Cockayne Syndrome
    View official trial listing →
  • Active, not recruiting NCT NCT02962414

    Roll-over Study to Collect and Assess Long-term Safety of Everolimus in Patients With TSC and Refractory Seizures Who Have Completed the EXIST-3 Study [CRAD001M2304] and Who Are Benefitting From Continued Treatment

    Not yet reported Novartis Pharmaceuticals 206 participants Est. completion 2026-12-30 67 sites
    Other conditions: Tuberous Sclerosis Complex
    View official trial listing →
  • Status unknown NCT NCT02968927

    TB Host Directed Therapy

    Not yet reported The Aurum Institute NPC 200 participants Est. completion 2020-12 1 site
    Other conditions: Tuberculosis
    View official trial listing →
  • Completed NCT NCT02970630

    Envarsus® Once Daily With Everolimus in Elderly Kidney Transplant Recipients: Pharmacokinetic and Clinical Study

    Not yet reported Chiesi Farmaceutici S.p.A. 28 participants Est. completion 2018-02-22 6 sites
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Status unknown NCT NCT02972671

    Trial of MiStent Compared to Xience in Japan

    Not yet reported Micell Technologies 120 participants Est. completion 2022-04-30 10 sites Stand-alone
    Other conditions: Coronary (Artery); Disease
    View official trial listing →
  • Completed NCT NCT02973204

    Circulating Tumor Cells and Tumor DNA in HCC and NET

    University of Aarhus 167 participants Est. completion 2020-01-08 1 site
    Other conditions: Carcinoma, Hepatocellular, Neuroendocrine Tumors
    View official trial listing →
  • Terminated NCT NCT02974686

    Conversion From MPA to Zortress (Everolimus) for GI Toxicity Post-renal Transplantation

    Not yet reported Washington University School of Medicine 1 participants Est. completion 2019-09 1 site
    Other conditions: Kidney Transplant Rejection, Gastrointestinal Disorder, Functional
    View official trial listing →
  • Completed NCT NCT02975882

    Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

    Not yet reported Children's Oncology Group 33 participants Est. completion 2024-12-31 21 sites Stand-alone
    Other conditions: Childhood Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Recurrent Primary Central Nervous System Neoplasm, Refractory Malignant Solid Neoplasm, Refractory Primary Central Nervous System Neoplasm
    View official trial listing →
  • Completed NCT NCT02978456

    Quantitative Coronary Angiography Versus Intravascular Ultrasound GUIDancE for Drug-Eluting Stent Implantation

    Not yet reported CHEOL WHAN LEE, M.D., Ph.D 1528 participants Est. completion 2022-08-23 6 sites Stand-alone
    Other conditions: Coronary Disease, Coronary Stenoses
    View official trial listing →
  • Active, not recruiting NCT NCT02979873

    Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

    Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 84 participants Est. completion 2030-06-30 1 site Stand-alone
    Other conditions: Severe Aplastic Anemia
    View official trial listing →
  • Completed NCT NCT02985125

    LEE011 Plus Everolimus in Patients With Metastatic Pancreatic Adenocarcinoma Refractory to Chemotherapy

    Not yet reported, Not yet reported Georgetown University 12 participants Est. completion 2020-09-28 1 site
    Other conditions: Metastatic Pancreatic Adenocarcinoma
    View official trial listing →
  • Terminated NCT NCT02987959

    Study of TAK-228 (MLN0128) in Soft Tissue Sarcomas

    Not yet reported Fox Chase Cancer Center 6 participants Est. completion 2020-07-24 1 site
    Other conditions: Soft-tissue Sarcoma
    View official trial listing →
  • Withdrawn NCT NCT02990312

    Impact of Sirolimus and Maraviroc on CCR5 Expression and the HIV-1 Reservoir in HIV-infected Kidney Transplant Recipients

    Not yet reported University of Maryland, Baltimore Est. completion 2019-07-17 1 site Stand-alone
    Other conditions: Hiv, Kidney Transplant, HIV Reservoir, CCR5
    View official trial listing →
  • Completed NCT NCT02991807

    RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

    Not yet reported, Not yet reported Boston Children's Hospital 46 participants Est. completion 2021-12-22 3 sites
    Other conditions: PTEN Gene Mutation, PTEN Hamartoma Tumor Syndrome
    View official trial listing →
  • Terminated NCT NCT02991898

    Adoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme Malignancies

    Not yet reported Masonic Cancer Center, University of Minnesota 3 participants Est. completion 2019-06-20 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Burkitt Lymphoma, Natural Killer Cell Malignancies, Chronic Myelogenous Leukemia, Myelodysplastic Syndromes, Large-cell Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone B-Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Leukemia, Hodgkin Lymphoma, Multiple Myeloma, Acute Myelogenous Leukemia, Biphenotypic Leukemia, Undifferentiated Leukemia
    View official trial listing →
  • Completed NCT NCT02995096

    Tumor Characteristics, Pre-transplant Treatments and Immunosuppression After Liver Transplantation for Hepatocellular Carcinoma

    Rigshospitalet, Denmark 23124 participants Est. completion 2019-03
    Other conditions: Liver Transplantation
    View official trial listing →
  • Completed NCT NCT02996318

    Treatment of Coronary In-Stent Restenosis by a Sirolimus (Rapamycin) Coated Balloon or a Paclitaxel Coated Balloon

    Not yet reported InnoRa GmbH 50 participants Est. completion 2017-12-01 5 sites Stand-alone
    Other conditions: DES In-stent Stenosis
    View official trial listing →
  • Status unknown NCT NCT03008083

    Comparison Three vs Twelve Months of Dual Anti-Platelet Therapy After Stent Implantation

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 2446 participants Est. completion 2022-10 1 site
    Other conditions: Drug-Eluting Stents, Percutaneous Coronary Intervention
    View official trial listing →
  • Status unknown NCT NCT03008148

    Phase II/III Trial of CCRT With or Without JP001 for Newly Diagnosed GBM

    Not yet reported, Not yet reported Johnpro Biotech, Inc. 288 participants Est. completion 2025-04 2 sites
    Other conditions: Glioblastoma
    View official trial listing →
  • Active, not recruiting NCT NCT03008408

    A Phase II, Two-Arm Study of Everolimus and Letrozole, +/- Ribociclib (Lee011) in Patients With Advanced or Recurrent Endometrial Carcinoma

    Not yet reported M.D. Anderson Cancer Center 90 participants Est. completion 2028-08-31 2 sites
    Other conditions: Recurrent Endometrial Carcinoma, Recurrent Endometrial Endometrioid Adenocarcinoma, Refractory Endometrial Carcinoma, Refractory Endometrial Endometrioid Adenocarcinoma, Stage III Uterine Corpus Cancer AJCC v8, Stage IIIA Uterine Corpus Cancer AJCC v8, Stage IIIB Uterine Corpus Cancer AJCC v8, Stage IIIC Uterine Corpus Cancer AJCC v8, Stage IIIC1 Uterine Corpus Cancer AJCC v8, Stage IIIC2 Uterine Corpus Cancer AJCC v8, Stage IV Uterine Corpus Cancer AJCC v8, Stage IVA Uterine Corpus Cancer AJCC v8, Stage IVB Uterine Corpus Cancer AJCC v8
    View official trial listing →
  • Terminated NCT NCT03014297

    Fosbretabulin With Everolimus in Neuroendocrine Tumors With Progression

    Not yet reported Lowell Anthony, MD 17 participants Est. completion 2018-11-16 1 site
    Other conditions: Neuroendocrine Tumors, Everolimus
    View official trial listing →
  • Status unknown NCT NCT03016715

    Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study

    Not yet reported Premier Specialists, Australia 8 participants 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Weber-Cockayne Syndrome
    View official trial listing →
  • Completed NCT NCT03018223

    Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 32 participants Est. completion 2021-03-18 1 site Stand-alone
    Other conditions: Non-Hodgkin's Lymphoma, Acute Leukemia in Remission, Chronic Myeloid Leukemia, Primary Myelofibrosis, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Hodgkin Lymphoma, Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT03026465

    Vessel Injury in Relation With Strut Thickness Assessed by OCT

    Not yet reported Fundacion Investigacion Interhospitalaria Cardiovascular 50 participants Est. completion 2018-07-27 3 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT03027856

    The BIFSORB Pilot Study II

    Not yet reported Aarhus University Hospital Skejby 20 participants Est. completion 2024-12-31 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT03032406

    CLEVER Pilot Trial: A Phase II Pilot Trial of HydroxyChLoroquine, EVErolimus or the Combination for Prevention of Recurrent Breast Cancer

    Not yet reported Abramson Cancer Center at Penn Medicine 53 participants Est. completion 2027-01-01 1 site
    Other conditions: Breast Cancer Stage IIB
    View official trial listing →
  • Status unknown NCT NCT03040934

    Firehawk™ Coronary Stent System in the Treatment of Coronary Chronic Total Occlusion Lesion(s)

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 196 participants Est. completion 2023-10 1 site
    Other conditions: Drug-Eluting Stents, Percutaneous Coronary Intervention, Tomography, Optical Coherence
    View official trial listing →
  • Active, not recruiting NCT NCT03047213

    Sapanisertib in Treating Patients With Locally Advanced or Metastatic Bladder Cancer With TSC1 and/or TSC2 Mutations

    Not yet reported National Cancer Institute (NCI) 17 participants Est. completion 2026-11-12 20 sites
    Other conditions: Locally Advanced Bladder Urothelial Carcinoma, Metastatic Transitional Cell Carcinoma, Metastatic Urothelial Carcinoma, Recurrent Bladder Carcinoma, Stage III Bladder Urothelial Carcinoma AJCC v6 and v7, Stage IV Bladder Urothelial Carcinoma AJCC v7
    View official trial listing →
  • Completed NCT NCT03047980

    Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome

    Not yet reported, Not yet reported Anne Comi, MD 10 participants Est. completion 2020-10-27 2 sites Stand-alone
    Other conditions: Sturge-Weber Syndrome
    View official trial listing →
  • Active, not recruiting NCT NCT03049189

    Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients

    Not yet reported ITM Solucin GmbH 324 participants Est. completion 2029-11 52 sites
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Terminated NCT NCT03061708

    Trial of Single Agent AZD2014 in RICTOR Amplified GC Patients as Second-line Therapy

    Not yet reported Samsung Medical Center 1 participants Est. completion 2018-11-16 1 site
    Other conditions: Stomach Neoplasms
    View official trial listing →
  • Suspended NCT NCT03065062

    Study of the CDK4/6 Inhibitor Palbociclib (PD-0332991) in Combination With the PI3K/mTOR Inhibitor Gedatolisib (PF-05212384) for Patients With Advanced Squamous Cell Lung, Pancreatic, Head & Neck and Other Solid Tumors

    Not yet reported Dana-Farber Cancer Institute 75 participants Est. completion 2027-01-31 3 sites
    Other conditions: Lung Cancer Squamous Cell, Solid Tumors, Head & Neck Cancer, Pancreatic Cancer
    View official trial listing →
  • Terminated NCT NCT03065387

    Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

    Not yet reported M.D. Anderson Cancer Center 84 participants Est. completion 2026-04-23 1 site
    Other conditions: Advanced Malignant Solid Neoplasm, EGFR Gene Amplification, EGFR Gene Mutation, ERBB2 Gene Amplification, ERBB2 Gene Mutation, ERBB3 Gene Mutation, ERBB4 Gene Mutation, KRAS Gene Mutation, Metastatic Malignant Solid Neoplasm, Refractory Malignant Solid Neoplasm
    View official trial listing →
  • Completed NCT NCT03070301

    A Study of LEE011 With Everolimus in Patients With Advanced Neuroendocrine Tumors

    Not yet reported Memorial Sloan Kettering Cancer Center 21 participants Est. completion 2024-01-31 5 sites
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Completed NCT NCT03072485

    Phase 1 Study of the Effects of Combining Topical FDA-approved Drugs on Age-related Pathways on the Skin of Healthy Volunteers

    Not yet reported Anne Chang 10 participants Est. completion 2019-02-22 1 site
    Other conditions: Aging
    View official trial listing →
  • Active, not recruiting NCT NCT03077542

    Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

    Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 57 participants Est. completion 2026-08-31 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Terminated NCT NCT03082833

    Phase II Trial of AZD2014 in TSC1/2 Mutated or TSC1/2 Null GC Patients as Second-line Chemotherapy

    Not yet reported Samsung Medical Center 1 participants Est. completion 2018-11-16 1 site
    Other conditions: Cancer of Stomach
    View official trial listing →
  • Completed NCT NCT03085823

    The All-comers Sirolimus-coated Balloon European Registry

    Fatebenefratelli and Ophthalmic Hospital 2123 participants Est. completion 2022-01 1 site
    Other conditions: Percutaneous Coronary Intervention, Angioplasty, Balloon, Coronary, Coronary Angioplasty, Transluminal Balloon, Arteriosclerosis, Coronary
    View official trial listing →
  • Status unknown NCT NCT03089450

    To Evaluate Safety and Efficacy of CGBIO Stent Compared to Biomatrix Flex Stent

    Not yet reported CGBio Inc. 112 participants Est. completion 2018-06 1 site Stand-alone
    Cardiovascular disease Other conditions: Ischemic Heart Disease, Stable Angina, Unstable Angina, NSTEMI - Non-ST Segment Elevation MI
    View official trial listing →
  • Completed NCT NCT03091465

    Validation of the International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) Prognostic Classification for Targeted Therapies (TKI/mTOR Inhibitors) in Second Line After First Line Treatment With Pazopanib

    Spanish Oncology Genito-Urinary Group 530 participants Est. completion 2017-04-17 57 sites
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT03095040

    CM082 Combined With Everolimus in Chinese Patients With Metastatic Renal Cell Carcinoma

    Not yet reported AnewPharma 390 participants Est. completion 2021-12 1 site
    Other conditions: Renal Cell Cancer Metastatic
    View official trial listing →
  • Completed NCT NCT03095703

    Sirolimus and Familial Adenomatous Polyposis (FAP)

    Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 4 participants Est. completion 2018-12-10 1 site Stand-alone
    Other conditions: Adenomatous Polyposis Coli
    View official trial listing →
  • Completed NCT NCT03103893

    Novel Compositions for Treating or Preventing Dermal Disorders

    Not yet reported, Not yet reported Drexel University 36 participants Est. completion 2017-11-30 1 site
    Other conditions: Dermal Atrophy
    View official trial listing →
  • Completed NCT NCT03112603

    A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)

    Not yet reported Incyte Corporation 330 participants Est. completion 2022-12-15 191 sites
    Other conditions: Graft-versus-host Disease (GVHD)
    View official trial listing →
  • Active, not recruiting NCT NCT03114527

    Phase II Trial of Ribociclib and Everolimus in Advanced Dedifferentiated Liposarcoma (DDL) and Leiomyosarcoma (LMS)

    Not yet reported Fox Chase Cancer Center 48 participants Est. completion 2026-12 2 sites
    Other conditions: Soft Tissue Sarcoma
    View official trial listing →
  • Withdrawn NCT NCT03120000

    PQR309 in Phase 2 in Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma

    Not yet reported PIQUR Therapeutics AG Est. completion 2019-12 4 sites
    Other conditions: Primary Central Nervous System Lymphoma
    View official trial listing →
  • Completed NCT NCT03125772

    Trial on Safety & Performance of TAXUS Element vs. XIENCE Prime Stent in Treatment of Coronary Lesion in Diabetics

    Not yet reported Fortis Escorts Heart Institute 1830 participants Est. completion 2016-05 1 site
    Type 2 diabetes Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT03131999

    LAM Pilot Study With Imatinib Mesylate

    Not yet reported, Not yet reported Medical University of South Carolina 18 participants Est. completion 2019-03-07 2 sites Stand-alone
    Other conditions: Lymphangioleiomyomatosis
    View official trial listing →
  • Suspended NCT NCT03139747

    UPCC 36315 A Phase II Study Of Everolimus (RAD001) And Lenvatinib (E7080) In Patients With Metastatic Differentiated Thyroid Cancer Who Have Progressed on Lenvatinib Alone

    Not yet reported Thomas Jefferson University 5 participants Est. completion 2022-05-30 1 site
    Other conditions: Thyroid Cancer
    View official trial listing →
  • Completed NCT NCT03140449

    Topical Rapamycin and Calcitriol for Angiofibroma of Tuberous Sclerosis

    Not yet reported National Taiwan University Hospital 52 participants Est. completion 2017-04-25
    Other conditions: Facial Angiofibroma
    View official trial listing →
  • Active, not recruiting NCT NCT03150914

    Multicenter Interventional Lymphangioleiomyomatosis (LAM) Early Disease Trial

    Not yet reported University of Cincinnati 60 participants Est. completion 2025-06-30 8 sites
    Other conditions: LAM, Lymphangioleiomyomatosis
    View official trial listing →
  • Completed NCT NCT03154281

    Evaluation of the Safety and Tolerability of Niraparib With Everolimus in Advanced Gynecologic Malignancies and Breast

    Not yet reported Avera McKennan Hospital & University Health Center 14 participants Est. completion 2023-05-01 1 site
    Other conditions: Breast Cancer, Ovarian Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT03155620

    Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

    Not yet reported National Cancer Institute (NCI) 1377 participants Est. completion 2027-01-06 172 sites
    Obstructive sleep apnea Other conditions: Advanced Malignant Solid Neoplasm, Ann Arbor Stage III Non-Hodgkin Lymphoma, Ann Arbor Stage IV Non-Hodgkin Lymphoma, Histiocytic Sarcoma, Juvenile Xanthogranuloma, Langerhans Cell Histiocytosis, Malignant Glioma, Recurrent Ependymoma, Recurrent Ewing Sarcoma, Recurrent Glioma, Recurrent Hepatoblastoma, Recurrent Langerhans Cell Histiocytosis, Recurrent Malignant Germ Cell Tumor, Recurrent Malignant Solid Neoplasm, Recurrent Medulloblastoma, Recurrent Neuroblastoma, Recurrent Non-Hodgkin Lymphoma, Recurrent Peripheral Primitive Neuroectodermal Tumor, Recurrent Primary Central Nervous System Neoplasm, Recurrent Rhabdoid Tumor, Recurrent Soft Tissue Sarcoma, Refractory Ewing Sarcoma, Refractory Glioma, Refractory Hepatoblastoma, Refractory Langerhans Cell Histiocytosis, Refractory Malignant Germ Cell Tumor, Refractory Malignant Solid Neoplasm, Refractory Medulloblastoma, Refractory Neuroblastoma, Refractory Non-Hodgkin Lymphoma, Refractory Peripheral Primitive Neuroectodermal Tumor, Refractory Primary Central Nervous System Neoplasm, Refractory Rhabdoid Tumor, Rhabdoid Tumor, Stage III Soft Tissue Sarcoma AJCC v7, Stage IV Soft Tissue Sarcoma AJCC v7, Wilms Tumor
    View official trial listing →
  • Completed NCT NCT03158389

    NCT Neuro Master Match - N²M² (NOA-20)

    Not yet reported, Not yet reported University Hospital Heidelberg 228 participants Est. completion 2023-02-22 13 sites
    Other conditions: Glioblastoma, Adult
    View official trial listing →
  • Completed NCT NCT03161340

    Immunomodulatory Effects of Rapamycin on Pregnancy Rate of Patient With Recurrent Implantation Failure

    Not yet reported Mehdi Yousefi 121 participants Est. completion 2018-06-20 2 sites
    Other conditions: Recurrent Implantation Failure
    View official trial listing →
  • Completed NCT NCT03163667

    CB-839 With Everolimus vs. Placebo With Everolimus in Participants With Renal Cell Carcinoma (RCC)

    Not yet reported Calithera Biosciences, Inc 69 participants Est. completion 2020-06-01 38 sites
    Other conditions: Clear Cell Renal Cell Carcinoma
    View official trial listing →
  • Withdrawn NCT NCT03166904

    Phase II Trial of AZD2014 in RICTOR Amplified Solid Cancer Patients Refractory to Standard Chemotherapy

    Not yet reported Samsung Medical Center Est. completion 2018-07-31 1 site
    Other conditions: Solid Tumor
    View official trial listing →
  • Completed NCT NCT03173560

    Trial to Assess Safety and Efficacy of Lenvatinib (18 mg vs. 14 mg) in Combination With Everolimus in Participants With Renal Cell Carcinoma

    Not yet reported Eisai Inc. 343 participants Est. completion 2024-06-20 93 sites
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT03174171

    Open-label Study on Treatment of Primary Aldosteronism With Everolimus

    Not yet reported University Hospital, Basel, Switzerland 12 participants Est. completion 2018-06-25 1 site
    Other conditions: Primary Aldosteronism
    View official trial listing →
  • Completed NCT NCT03176238

    Study in Post-menopausal Women With Hormone Receptor Positive, HER2-negative Advanced Breast Cancer

    Not yet reported Novartis Pharmaceuticals 235 participants Est. completion 2019-01-29 55 sites
    Other conditions: Post Menopausal Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT03185221

    Cordimax China Post Market Surveillance

    Not yet reported Shandong Branden Med.Device Co.,Ltd 3660 participants Est. completion 2020-06-20 1 site
    Other conditions: Coronary Artery Stenosis
    View official trial listing →
  • Completed NCT NCT03188068

    Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma

    Not yet reported West China Hospital 30 participants Est. completion 2021-12-31 1 site
    Other conditions: Kaposiform Hemangioendothelioma, Kasabach Merritt Phenomenon
    View official trial listing →
  • Completed NCT NCT03190174

    Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers

    Not yet reported, Not yet reported Sarcoma Oncology Research Center, LLC 34 participants Est. completion 2021-12-02 1 site
    Other conditions: Ewing Sarcoma, PEComa, Epithelioid Sarcoma, Desmoid Tumor, Chordoma, Non Small Cell Lung Cancer, Urothelial Carcinoma, Melanoma, Renal Cell Carcinoma, Squamous Cell Carcinoma, Hepatocellular Carcinoma, Classical Hodgkin Lymphoma, Colorectal Cancer, MTOR Activating Mutation
    View official trial listing →
  • Terminated NCT NCT03190473

    OPTIMIZE IDE for the Treatment of ACS

    Not yet reported Svelte Medical Systems, Inc. 1630 participants Est. completion 2023-03-08 72 sites
    Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Active, not recruiting NCT NCT03192397

    Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

    Not yet reported, Not yet reported Roswell Park Cancer Institute 35 participants Est. completion 2027-05-21 1 site Stand-alone
    Other conditions: Acute Myeloid Leukemia in Remission, Adult Acute Lymphoblastic Leukemia in Complete Remission, Chronic Myelogenous Leukemia, BCR-ABL1 Positive in Remission, Chronic Myelomonocytic Leukemia in Remission, Graft Versus Host Disease, Hodgkin Lymphoma, Minimal Residual Disease, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Non-Hodgkin Lymphoma, Plasma Cell Myeloma, Severe Aplastic Anemia, Waldenstrom Macroglobulinemia
    View official trial listing →
  • Completed NCT NCT03198949

    A Study Investigating the Anti-epileptic Efficacy of Afinitor (Everolimus) in Patients With Refractory Seizures Who Have Focal Cortical Dysplasia Type II (FCD II)

    Not yet reported Yonsei University 23 participants Est. completion 2020-09-11 1 site
    Other conditions: Epilepsy and Focal Cortical Dysplasia II
    View official trial listing →
  • Status unknown NCT NCT03199014

    the Effect of Prolonged Inflation Time During Stents Deployment for ST-elevation Myocardial Infarction

    Not yet reported West China Hospital 60 participants Est. completion 2017-07 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT03203525

    Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

    Not yet reported M.D. Anderson Cancer Center 38 participants Est. completion 2026-07-22 1 site
    Other conditions: Advanced Malignant Neoplasm, Colorectal Carcinoma Metastatic in the Liver, Metastatic Malignant Neoplasm in the Liver, Refractory Malignant Neoplasm
    View official trial listing →
  • Terminated NCT NCT03205046

    A Study of Acalabrutinib and Vistusertib in Subjects With Relapsed/Refractory B-cell Malignancies

    Not yet reported, Not yet reported Acerta Pharma BV 25 participants Est. completion 2019-11-20 11 sites
    Other conditions: DLBCL, Richter Syndrome
    View official trial listing →
  • Active, not recruiting NCT NCT03216733

    SORT OUT X - Combo Stent Versus ORSIRO Stent

    Not yet reported Aarhus University Hospital Skejby 3148 participants Est. completion 2028-12-31 4 sites
    Cardiovascular disease Other conditions: Coronary Heart Disease, Angina Pectoris
    View official trial listing →
  • Completed NCT NCT03216967

    Multicenter Randomized Two-arms Study Evaluating the BK Viral Clearance in Kidney Transplant Recipients With BK Viremia.

    Not yet reported University Hospital, Strasbourg, France 130 participants Est. completion 2024-08-01 15 sites
    Other conditions: BK Virus Nephropathy After Kidney Transplantation
    View official trial listing →
  • Status unknown NCT NCT03217669

    Epacadostat (INCB24360) in Combination With Sirolimus in Advanced Malignancy

    Not yet reported Chao Huang 15 participants Est. completion 2025-08-01 2 sites Stand-alone
    Other conditions: Advanced Solid Tumor, Non-small Cell Lung Cancer (NSCLC)
    View official trial listing →
  • Status unknown NCT NCT03225417

    Ixazomib in the Prophylaxis of Chronic Graft-versus-host Disease.

    Not yet reported, Not yet reported Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 142 participants Est. completion 2024-12-31 8 sites Stand-alone
    Other conditions: Hematopoietic Stem Cell Transplantation, Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT03234348

    MAGnesium-based Bioresorbable Scaffold in ST Segment Elevation Myocardial Infarction

    Not yet reported Hospital Clinic of Barcelona 151 participants Est. completion 2019-10-31 11 sites Stand-alone
    Cardiovascular disease Other conditions: Acute Coronary Syndrome, Stent
    View official trial listing →
  • Status unknown NCT NCT03239015

    Efficacy and Safety of Precision Therapy in Refractory Tumor

    Not yet reported Baodong Qin 300 participants Est. completion 2023-12-31 1 site
    Other conditions: Rare Tumor, Refractory Tumor
    View official trial listing →
  • Completed NCT NCT03240731

    HLA Haploidentical Bone Marrow Transplant in Patients With Severe Sickle Cell Disease

    Not yet reported Centre Hospitalier Intercommunal Creteil 25 participants Est. completion 2024-04-08 7 sites Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Completed NCT NCT03242096

    Treatment of Coronary In-stent Restenosis (ISR) by a Sirolimus Coated or a Paclitaxel Coated Balloon

    Not yet reported InnoRa GmbH 50 participants Est. completion 2021-01-31 5 sites Stand-alone
    Other conditions: Coronary Restenosis
    View official trial listing →
  • Completed NCT NCT03245151

    Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric Solid Tumors, Including Central Nervous System Tumors

    Not yet reported, Not yet reported Eisai Inc. 64 participants Est. completion 2022-09-30 50 sites
    Other conditions: Recurrent and Refractory Solid Tumors
    View official trial listing →
  • Terminated NCT NCT03246906

    Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation

    Not yet reported Fred Hutchinson Cancer Center 150 participants Est. completion 2025-05-03 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Aggressive Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma, Mantle Cell Lymphoma, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Hodgkin Lymphoma, Recurrent Plasma Cell Myeloma, Recurrent Small Lymphocytic Lymphoma, Recurrent Waldenstrom Macroglobulinemia, Hematologic and Lymphocytic Disorder, Blastic Plasmacytoid Dendritic Cell Neoplasm
    View official trial listing →
  • Completed NCT NCT03253913

    Resveratrol and Sirolimus in Lymphangioleiomyomatosis Trial

    Not yet reported University of Cincinnati 25 participants Est. completion 2022-10-15 1 site Stand-alone
    Other conditions: Lymphangioleiomyomatosis
    View official trial listing →
  • Completed NCT NCT03256864

    Twice-daily Tacrolimus and Everolimus Convert to Once-daily Tacrolimus and Everolimus in Liver Transplant Recipient

    Not yet reported Chang Gung Memorial Hospital 10 participants Est. completion 2020-05-30 1 site
    Other conditions: Liver Transplantation
    View official trial listing →
  • Completed NCT NCT03263260

    Post-marketing Registry of Inspiron Sirolimus Eluting Coronary Stent

    Scitech Produtos Medicos SA 2504 participants Est. completion 2024-01-21 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT03263559

    Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)

    Not yet reported Medical College of Wisconsin 95 participants Est. completion 2025-01-29 32 sites Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Status unknown NCT NCT03284255

    Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System Clinical Study

    Not yet reported Shanghai Bio-heart Biological Technology Co., Ltd. 431 participants Est. completion 2024-08-30 25 sites
    Cardiovascular disease Other conditions: Antineoplastic Agents
    View official trial listing →
  • Terminated NCT NCT03284957

    Phase 1/2 Study of Amcenestrant (SAR439859) Single Agent and in Combination With Other Anti-cancer Therapies in Postmenopausal Women With Estrogen Receptor Positive Advanced Breast Cancer

    Not yet reported, Not yet reported Sanofi 136 participants Est. completion 2024-11-08 25 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT03285802

    Treatment Plan for an Individual Patient With Recurrent Uterine Papillary Serous Carcinoma (UPSC) With PIK3CA Gene Mutation

    Not yet reported, Not yet reported Greater Baltimore Medical Center 1 participants Est. completion 2019-02-12 1 site
    Other conditions: Uterine Cancer
    View official trial listing →
  • Status unknown NCT NCT03287167

    Comparison One vs Six Months of Dual Antiplatelet Therapy After Implanted Firehawk TM Stent in High Bleeding Risk Patients With Coronary Artery Disease

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 1720 participants Est. completion 2023-07-30 1 site
    Other conditions: Coronary Disease, Drug Eluting Stent, Percutaneous Coronary Intervention, Dual Antiplatelet Therapy
    View official trial listing →
  • Enrolling by invitation NCT NCT03292861

    The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant Recipients

    Not yet reported Cedars-Sinai Medical Center 60 participants Est. completion 2026-03-31 2 sites
    Other conditions: Heart Transplantation
    View official trial listing →
  • Withdrawn NCT NCT03298958

    Secondary Prevention Trial of Rapamycin in Patients With Resected Non-muscle Invasive Bladder Cancer

    Not yet reported The University of Texas Health Science Center at San Antonio Est. completion 2022-05-01 1 site
    Other conditions: Bladder Cancer
    View official trial listing →
  • Completed NCT NCT03304678

    Discovery of Sirolimus Sensitive Biomarkers in Blood

    Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 33 participants Est. completion 2025-03-14 1 site
    Other conditions: Lymphangioleiomyomatosis
    View official trial listing →
  • Completed NCT NCT03312738

    A Study of Everolimus Plus Exemestane in Chinese Postmenopausal Women With Estrogen Receptor Positive, Locally Advanced, Recurrent, or Metastatic Breast Cancer After Recurrence or Progression on Non-steroidal Aromatase Inhibitor

    Not yet reported Novartis Pharmaceuticals 159 participants Est. completion 2022-04-25 15 sites
    Other conditions: Advanced Breast Cancer
    View official trial listing →
  • Completed NCT NCT03324373

    Lenvatinib and Everolimus in Renal Cell Carcinoma (RCC)

    Not yet reported Yousef Zakharia 11 participants Est. completion 2024-08-28 1 site
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT03328104

    Everolimus in Combination With Nelarabine, Cyclophosphamide and Etoposide in Lymphoblastic Leukemia/Lymphoma

    Not yet reported Emory University 8 participants Est. completion 2023-06-29 4 sites
    Other conditions: Lymphoblastic Leukemia, Lymphoblastic Lymphoma
    View official trial listing →
  • Terminated NCT NCT03333694

    Safety, Tolerability, and Efficacy Study of CLL442 in Patients With Cutaneous Squamous Cell Carcinoma in Situ (SCCis)

    Not yet reported Novartis Pharmaceuticals 40 participants Est. completion 2018-11-01 8 sites
    Other conditions: Cutaneous Squamous Cell Carcinoma in Situ (CSCCis)
    View official trial listing →
  • Active, not recruiting NCT NCT03334617

    Phase II Umbrella Study of Novel Anti-cancer Agents in Participants With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy

    Not yet reported AstraZeneca 528 participants Est. completion 2026-09-11 45 sites
    Other conditions: Non-Small Cell Lung Cancer
    View official trial listing →
  • Terminated NCT NCT03352427

    Study of Dasatinib in Combination With Everolimus for Children and Young Adults With Gliomas Harboring Platelet-Derived Growth Factor Receptor (PDGFR) Alterations

    Not yet reported University of Michigan Rogel Cancer Center 3 participants Est. completion 2019-05-15 1 site
    Other conditions: Glioma, High Grade Glioma, Pontine Tumors
    View official trial listing →
  • Completed NCT NCT03355794

    A Study of Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)

    Not yet reported Children's Hospital Medical Center, Cincinnati 19 participants Est. completion 2022-07-31 7 sites
    Other conditions: Diffuse Intrinsic Pontine Glioma, Malignant Glioma of Brain, High Grade Glioma, Bithalamic High Grade Glioma, Brainstem Glioma, Glioblastoma, Anaplastic Astrocytoma
    View official trial listing →
  • Completed NCT NCT03359538

    Rapamycin Treatment for ALS

    Not yet reported Azienda Ospedaliero-Universitaria di Modena 63 participants Est. completion 2022-02-15 7 sites
    Other conditions: Amyotrophic Lateral Sclerosis
    View official trial listing →
  • Terminated NCT NCT03363763

    Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex

    Not yet reported Aucta Pharmaceuticals, Inc 24 participants Est. completion 2023-03-24 8 sites
    Other conditions: Angiofibroma of Face, Tuberous Sclerosis
    View official trial listing →
  • Completed NCT NCT03364764

    Sirolimus Treatment for Refractory PRCA

    Not yet reported Bing Han 64 participants Est. completion 2021-05-01 1 site Stand-alone
    Other conditions: Pure Red Cell Aplasia
    View official trial listing →
  • Status unknown NCT NCT03365869

    A Pilot-Study of Sirolimus for the Treatment of Systemic Sclerosis

    Not yet reported Peking University People's Hospital 72 participants Est. completion 2019-06-30
    Other conditions: Systemic Sclerosis
    View official trial listing →
  • Completed NCT NCT03383380

    Rapamycin Treatment for Activated Phosphoinositide 3-Kinase δ Syndrome

    Not yet reported, Not yet reported Children's Hospital of Fudan University 30 participants Est. completion 2023-11-30 2 sites
    Other conditions: Activated PI3K-delta Syndrome, Immunodeficiency Primary
    View official trial listing →
  • Completed NCT NCT03386539

    Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score

    Not yet reported Boston Children's Hospital 211 participants Est. completion 2023-05-17 25 sites
    Chronic kidney disease Other conditions: Pediatric Heart Transplantation, Immunosuppression, Cardiac Allograft Vasculopathy, Heart Transplant Failure and Rejection, Post-transplant Lymphoproliferative Disorder, Heart Transplant Infection
    View official trial listing →
  • Completed NCT NCT03387020

    Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

    Not yet reported Pediatric Brain Tumor Consortium 22 participants Est. completion 2020-04-01 12 sites
    Other conditions: CNS Embryonal Tumor, Not Otherwise Specified, Malignant Glioma, Recurrent Atypical Teratoid/Rhabdoid Tumor, Recurrent Childhood Ependymoma, Recurrent Diffuse Intrinsic Pontine Glioma, Recurrent Medulloblastoma, Refractory Diffuse Intrinsic Pontine Glioma
    View official trial listing →
  • Completed NCT NCT03399994

    Clinical Trial of Abluminus DES+ Sirolimus Eluting Stent Versus Everolimus-eluting DES

    Not yet reported Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS 137 participants Est. completion 2022-07-26 6 sites
    Cardiovascular disease Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT03413722

    Alterations in Cognitive Function and Cerebral Blood Flow After Conversion From Calcineurin Inhibitors (CNIs) to Everolimus

    University of Kansas Medical Center 30 participants Est. completion 2022-10-01 1 site
    Other conditions: End Stage Renal Disease
    View official trial listing →
  • Completed NCT NCT03415750

    Everolimus and Tacrolimus Combination for Regression of Left Ventricular Hypertrophy in Renal Transplants

    Not yet reported Edoardo Melilli 20 participants Est. completion 2020-05 1 site
    Other conditions: Hypertrophy, Left Ventricular
    View official trial listing →
  • Terminated NCT NCT03421756

    Stem Cell Transplant in Patients With Severe Sickle Cell Disease

    Not yet reported Kathleen Dorritie 1 participants Est. completion 2022-05-15 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Completed NCT NCT03433183

    SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

    Not yet reported Sarcoma Alliance for Research through Collaboration 21 participants Est. completion 2023-10-01 5 sites Stand-alone
    Other conditions: Malignant Peripheral Nerve Sheath Tumors, Neurofibromatosis 1
    View official trial listing →
  • Completed NCT NCT03434704

    Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazole

    Not yet reported Ciceri Fabio 10 participants Est. completion 2019-10-13 1 site Stand-alone
    Other conditions: Transplant-Related Hematologic Malignancy, Leukemia, Acute, Myelodysplastic Syndromes, Graft Vs Host Disease, Fungal Infection
    View official trial listing →
  • Terminated NCT NCT03436732

    Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesothelioma

    Not yet reported National Cancer Institute (NCI) 5 participants Est. completion 2019-04-30 1 site
    Other conditions: Mesothelioma
    View official trial listing →
  • Completed NCT NCT03439462

    Nab-Sirolimus in Combination With FOLFOX & BEV as 1st Line Therapy in Patients With Advanced or Metastatic Colorectal Cancer

    Not yet reported, Not yet reported Aadi Bioscience, Inc. 60 participants Est. completion 2022-08-26 6 sites Stand-alone
    Other conditions: Colorectal Cancer Metastatic
    View official trial listing →
  • Status unknown NCT NCT03454724

    Study of MeRes100 in the Treatment of Patient With Coronary Artery Disease.

    Not yet reported Meril Life Sciences Pvt. Ltd. 484 participants Est. completion 2024-12-01 Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT03456700

    Auranofin and Sirolimus in Treating Participants With Ovarian Cancer

    Not yet reported Mayo Clinic 22 participants Est. completion 2019-07-31 1 site Stand-alone
    Other conditions: Ovarian Serous Tumor, Recurrent Ovarian Carcinoma
    View official trial listing →
  • Completed NCT NCT03463265

    Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed Glioblastoma

    Not yet reported Aadi Bioscience, Inc. 62 participants Est. completion 2022-08-26 3 sites Stand-alone
    Other conditions: High Grade Recurrent Glioma and Newly Diagnosed Glioblastoma
    View official trial listing →
  • Completed NCT NCT03468478

    Comparison of the Efficacy and Safety of Sirolimus Versus Everolimus Versus Mycophenolate in Kidney Transplantation

    Not yet reported Hospital do Rim e Hipertensão 1209 participants Est. completion 2021-08-23 1 site Stand-alone
    Other conditions: Kidney Transplant Infection
    View official trial listing →
  • Completed NCT NCT03471234

    Latin America Real World Study With Inspiron Drug Eluting Stent - INSPIRON LATITUDE

    Scitech Produtos Medicos SA 299 participants Est. completion 2022-08-02 2 sites
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT03475563

    BiOSS Study (BiOSS LIM C Stent Registry in Bifurcated Lesions)

    Hospital Universitari Vall d'Hebron Research Institute 100 participants Est. completion 2019-12-30 3 sites
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT03484234

    Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-VII: Sirolimus-eluting (Ultimaster) vs. Everolimus-Eluting Stents (Xience)

    Not yet reported Seung-Jung Park 36 participants Est. completion 2019-09-06 2 sites
    Cardiovascular disease Other conditions: Coronary Stenosis
    View official trial listing →
  • Status unknown NCT NCT03486366

    Application of Novel Diagnostic and Therapeutical Methods in Epilepsy and Neurodevelopmental Abnormalities in Children.

    Not yet reported Medical University of Warsaw 120 participants Est. completion 2020-03-30 1 site
    Other conditions: Epilepsy
    View official trial listing →
  • No Longer Available NCT NCT03493152

    Expanded Access to Everolimus, for an Individual Patient With GIST (Gastrointestinal Stromal Tumors)(CTMS#18-0019)

    The University of Texas Health Science Center at San Antonio
    Other conditions: Gastrointestinal Stromal Tumor
    View official trial listing →
  • No Longer Available NCT NCT03493165

    Expanded Access to Everolimus, for an Individual Patient With Uterine Sarcoma (CTMS#18-0020)

    The University of Texas Health Science Center at San Antonio
    Other conditions: Uterine Sarcoma
    View official trial listing →
  • Status unknown NCT NCT03500367

    Efficacy and Safety of Rapamycin (Sirolimus) in the Treatment of Symptomatic Uterine Fibroids and Leiomyomatosis

    Not yet reported Peking Union Medical College Hospital 25 participants Est. completion 2022-12-31 1 site
    Other conditions: Uterine Fibroids
    View official trial listing →
  • Status unknown NCT NCT03500848

    Sirolimus-based Immunosuppression Treatment Regimen for Liver Transplantation

    Not yet reported, Not yet reported Southern Medical University, China 130 participants Est. completion 2023-05-31 3 sites Stand-alone
    Other conditions: Liver Transplantation
    View official trial listing →
  • Completed NCT NCT03502902

    The Safety, Tolerability and Pharmacokinetic Study of HEC68498 in Healthy Male and Female Subjects

    Not yet reported Sunshine Lake Pharma Co., Ltd. 55 participants Est. completion 2019-03-15 1 site
    Other conditions: Idiopathic Pulmonary Fibrosis
    View official trial listing →
  • Completed NCT NCT03504241

    Tolerance by Engaging Antigen During Cellular Homeostasis

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 8 participants Est. completion 2025-09-16 1 site Stand-alone
    Other conditions: Kidney Transplantation, Renal Transplantation, Renal Transplant Recipient
    View official trial listing →
  • Completed NCT NCT03507205

    Korean Nationwide Multicenter Pooled Registry of Drug-Eluting Stents

    Seoul National University Hospital 17286 participants Est. completion 2017-11-30 37 sites
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT03508219

    POLish Bifurcation Optimal Treatment Strategy Study for Left Main Bifurcation Percutaneous Coronary Intervention (PCI)

    Not yet reported ECRI bv 130 participants Est. completion 2021-04-15 15 sites Stand-alone
    Other conditions: Coronary Stenosis
    View official trial listing →
  • Completed NCT NCT03509142

    A First-in-Man Study of IBS

    Not yet reported Lifetech Scientific (Shenzhen) Co., Ltd. 45 participants Est. completion 2023-12-10 1 site Stand-alone
    Other conditions: Single Coronary Vessel Disease
    View official trial listing →
  • Status unknown NCT NCT03509532

    DRUG ELUTING STENT FOR DIABETIC PATIENTS IN CORONARY ARTERY DISEASE TREATMENT

    I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio 5000 participants Est. completion 2022-01 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT03510676

    The ILLUMINA Study. (ILLUMINA)

    Not yet reported CID - Carbostent & Implantable Devices 100 participants Est. completion 2019-03-07 10 sites
    Other conditions: Peripheral Arterial Disease
    View official trial listing →
  • Terminated NCT NCT03512756

    A Randomized Phase 2/3 Multi-Center Study of SM-88 in Participants With Metastatic Pancreatic Cancer

    Not yet reported, Not yet reported Tyme, Inc 130 participants Est. completion 2021-12-28 20 sites Stand-alone
    Other conditions: Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT03522298

    Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

    Not yet reported Kazia Therapeutics Limited 30 participants Est. completion 2023-03-30 6 sites
    Other conditions: Glioblastoma, Adult
    View official trial listing →
  • Completed NCT NCT03525834

    Safety and Efficacy of Everolimus (Afinitor®) in Chinese Adult Patients With Angiomyolipoma Associated With Tuberous Sclerosis Complex.

    Not yet reported Novartis Pharmaceuticals 40 participants Est. completion 2020-09-25 5 sites
    Other conditions: Renal Angiomyolipoma
    View official trial listing →
  • Withdrawn NCT NCT03531281

    Human Lysozyme Goat Milk in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant

    Not yet reported City of Hope Medical Center Est. completion 2022-12-30 1 site Stand-alone
    Other conditions: Hematopoietic and Lymphoid Cell Neoplasm, Hematopoietic Cell Transplantation Recipient
    View official trial listing →
  • Status unknown NCT NCT03548272

    BiOSS LIM C vs 2nd Generation DES in Non-LM Bifurcations

    Not yet reported Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland 518 participants Est. completion 2020-06 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT03563989

    STENTYS Xposition S in the Treatment of Chronic Total Artery Occlusion

    Not yet reported Assistance Publique - Hôpitaux de Paris 50 participants Est. completion 2019-12 1 site Stand-alone
    Cardiovascular disease Other conditions: Chronic Total Occlusion
    View official trial listing →
  • Status unknown NCT NCT03571438

    Evaluation of a Promising New Combination of Protein Kinase Inhibitors on Organotypic Cultures of Human Renal Tumors

    Not yet reported University Hospital, Grenoble 100 participants Est. completion 2024-09-30 1 site
    Other conditions: Kidney Cancer
    View official trial listing →
  • Completed NCT NCT03577431

    Liver Transplantation With Tregs at MGH

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 9 participants Est. completion 2026-02-05 1 site
    Other conditions: Liver Transplant
    View official trial listing →
  • Terminated NCT NCT03578432

    Everolimus in Restoring Salivary Gland Function in Participants With Locally Advanced Head and Neck Cancer Treated With Radiation Therapy

    Not yet reported University of Arizona 2 participants Est. completion 2019-11-15 1 site
    Other conditions: Salivary Gland Dysfunction, Xerostomia, Head and Neck Cancer
    View official trial listing →
  • Status unknown NCT NCT03580239

    Everolimus in Castrated Resistant Prostate Cancer(CRPC)Patients With PI3K-AKT-mTOR Signaling Pathway Deficiency

    Not yet reported Tianjin Medical University Second Hospital 120 participants Est. completion 2023-12-01 4 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT03582878

    Sirolimus vs Mycophenolate With Tacrolimus in Simultaneous Pancreas and Kidney Transplantation

    Not yet reported Institute for Clinical and Experimental Medicine 238 participants Est. completion 2019-01-01 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT03583307

    Efficacy and Safety of Sirolimus to Vascular Anomalies

    Not yet reported West China Hospital 126 participants Est. completion 2021-02-19 1 site Stand-alone
    Other conditions: Vascular Anomaly
    View official trial listing →
  • Status unknown NCT NCT03587922

    FANTOM Post Market Clinical Trial

    Not yet reported REVA Medical, Inc. 1500 participants Est. completion 2025-05-01 10 sites
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT03589976

    A Futility Trial of Sirolimus in Multiple System Atrophy

    Not yet reported NYU Langone Health 47 participants Est. completion 2021-01-01 1 site Stand-alone
    Other conditions: Multiple System Atrophy
    View official trial listing →
  • Withdrawn NCT NCT03596970

    Study of the Effect of Everolimus Immunosuppressive Combination Therapies on Renal Function When Used as a Maintenance Treatment for Liver Transplant Patients.

    Not yet reported Novartis Pharmaceuticals Est. completion 2020-12
    Other conditions: Liver Transplantation
    View official trial listing →
  • Terminated NCT NCT03600948

    BIOFLOW-SV All Comers Registry

    Biotronik AG 261 participants Est. completion 2021-10-06 2 sites
    Other conditions: de Novo, Symptomatic Ischemic Heart Disease, Restenoses, Coronary
    View official trial listing →
  • Terminated NCT NCT03600961

    BIOFLOW-SV Portugal Registry

    Biotronik AG 173 participants Est. completion 2021-12-21 4 sites
    Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Completed NCT NCT03605927

    CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 45 participants Est. completion 2023-07-25 3 sites Stand-alone
    Other conditions: Graft-versus-host-disease, GVHD, GVHD, Acute
    View official trial listing →
  • Terminated NCT NCT03610347

    Paclitaxel Eluting Balloon After Bare Metal Stent Implantation vs. Drug-Eluting Stent in St Elevation Myocardial Infarction

    Not yet reported Fundacion Investigacion Interhospitalaria Cardiovascular 199 participants Est. completion 2020-03-31 16 sites
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT03616132

    A First-in-Man Study to Evaluate the Feasibility and Safety of Sirolimus-eluting Iron Bioresorbable Coronary Scaffold System

    Not yet reported Lifetech Scientific (Shenzhen) Co., Ltd. 15 participants Est. completion 2023-03-30 2 sites Stand-alone
    Other conditions: Single Coronary Vessel Disease
    View official trial listing →
  • Active, not recruiting NCT NCT03616587

    Study of AZD9833 Alone or in Combination in Women With Advanced Breast Cancer.

    Not yet reported AstraZeneca 396 participants Est. completion 2027-06-24 17 sites
    Other conditions: ER+ HER2- Advanced Breast Cancer
    View official trial listing →
  • Completed NCT NCT03618355

    Trial of eRapa in Prostate Cancer Patients

    Not yet reported Rapamycin Holdings, Inc. dba Emtora Biosciences 15 participants Est. completion 2019-12-02 1 site Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT03621501

    Direct Complete Versus Staged Complete Revascularization in Patients Presenting With Acute Coronary Syndromes and Multivessel Disease

    Not yet reported Erasmus Medical Center 1525 participants Est. completion 2026-10-31 1 site
    Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Status unknown NCT NCT03629847

    Treatment of Neuroendocrine Tumors (NETs) With Combination of Everolimus and Radiolabeled Somatostatin Analogue

    Not yet reported, Not yet reported King Faisal Specialist Hospital & Research Center 30 participants Est. completion 2018-12 1 site
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Withdrawn NCT NCT03632317

    A Study of Panobinostat in Combination With Everolimus for Children and Young Adults With Gliomas

    Not yet reported University of Michigan Rogel Cancer Center Est. completion 2025-10 1 site
    Other conditions: Glioma, Diffuse Intrinsic Pontine Glioma
    View official trial listing →
  • Completed NCT NCT03634020

    DynamX Sirolimus Study Sirolimus Eluting Coronary Bioadaptor System

    Not yet reported Elixir Medical Corporation 44 participants Est. completion 2021-03-08 7 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT03646240

    ABI-009 (Nab-rapamycin) for Surgically-Refractory Epilepsy (RaSuRE)

    Not yet reported Seattle Children's Hospital 14 participants Est. completion 2022-12-31 1 site
    Other conditions: Epilepsy Intractable
    View official trial listing →
  • Terminated NCT NCT03654040

    Liver Transplantation With Tregs at UCSF

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 42 participants Est. completion 2023-03-06 1 site
    Other conditions: Liver Transplant
    View official trial listing →
  • Withdrawn NCT NCT03657420

    Safety and Efficacy of ABI-009 (Nab-rapamycin) in Combination With Pomalidomide and Dexamethasone for Relapsed and Refractory Multiple Myeloma

    Not yet reported Massachusetts General Hospital Est. completion 2024-09-30 1 site
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT03659136

    The XENERA™ 1 Study Tests Xentuzumab in Combination With Everolimus and Exemestane in Women With Hormone Receptor Positive and HER2-negative Breast Cancer That Has Spread

    Not yet reported Boehringer Ingelheim 103 participants Est. completion 2022-05-11 54 sites
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Status unknown NCT NCT03660202

    Trial for MicroPort's Firesorb BVS: FUTURE-III

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 1200 participants Est. completion 2024-06 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT03660930

    Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas

    Not yet reported, Not yet reported University of Washington 19 participants Est. completion 2024-07-31 1 site Stand-alone
    Other conditions: Advanced Soft Tissue Sarcoma, Locally Advanced Soft Tissue Sarcoma, Metastatic Soft Tissue Sarcoma
    View official trial listing →
  • Status unknown NCT NCT03662412

    Study of Sirolimus in Patients With Advanced Pancreatic Cancer

    Not yet reported, Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 36 participants Est. completion 2023-06-30 1 site Stand-alone
    Other conditions: Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT03666208

    Sirolimus Coated Angioplasty Balloon in the Salvage of Thrombosed Arteriovenous Graft

    Not yet reported Singapore General Hospital 20 participants Est. completion 2019-09-02 1 site Stand-alone
    Other conditions: End Stage Renal Failure on Dialysis, Arteriovenous Graft Occlusion
    View official trial listing →
  • Completed NCT NCT03667313

    Treatment of In-Stent Restenosis 2 Study

    Not yet reported University Hospital Ostrava 200 participants Est. completion 2021-12-31 1 site Stand-alone
    Other conditions: Coronary Restenosis
    View official trial listing →
  • Terminated NCT NCT03670030

    A Study to testABI-009 in Patients With Metastatic, Unresectable, Low or Intermediate Grade Neuroendocrine Tumors of the Lung or Gastroenteropancreatic System

    Not yet reported Robert Ramirez 5 participants Est. completion 2021-02-26 1 site
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Status unknown NCT NCT03688191

    Study of Sirolimus in CTD-TP in China

    Not yet reported Peking Union Medical College Hospital 20 participants Est. completion 2019-09-30 1 site Stand-alone
    Other conditions: Connective Tissue Diseases, Thrombocytopenia
    View official trial listing →
  • Completed NCT NCT03696355

    Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas

    Not yet reported St. Jude Children's Research Hospital 27 participants Est. completion 2022-09-04 1 site
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Active, not recruiting NCT NCT03697408

    Itacitinib + Everolimus in Hodgkin Lymphoma

    Not yet reported, Not yet reported University of Pennsylvania 23 participants Est. completion 2027-06 1 site
    Other conditions: Classical Hodgkin Lymphoma
    View official trial listing →
  • Terminated NCT NCT03711929

    LUMINA Phase III Study Assessing the Efficacy and Safety of Intravitreal Injections of 440 ug DE-109 Sirolimus for the Treatment of Active, Non-Infectious Uveitis of the Posterior Segment of the Eye

    Not yet reported Santen Inc. 145 participants Est. completion 2022-06-14 65 sites
    Other conditions: Non Infectious Uveitis
    View official trial listing →
  • Status unknown NCT NCT03716011

    A Postmarket Clinical Trial for EXCROSSAL Stent in CAD Patients With 3-month DAPT or 12-month DAPT

    Not yet reported JW Medical Systems Ltd 2700 participants Est. completion 2025-12-20 1 site
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT03716102

    OPTIMIZE Sirolimus-Eluting Coronary Stent Systems Pharmacokinetics (PK) Study

    Not yet reported Svelte Medical Systems, Inc. 12 participants Est. completion 2021-07-15 2 sites Stand-alone
    Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Status unknown NCT NCT03721614

    Clinical Study Comparing Single Long BioMimeTM Morph Coronary Stent System vs. Two Overlapping Xience Family Coronary Stent Systems in the Treatment of Patients With Long de Novo Lesions.

    Not yet reported Meril Life Sciences Pvt. Ltd. 200 participants Est. completion 2022-06-22 Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT03730142

    A Study of WXFL10030390 in Patients With Advanced Solid Tumors or Lymphoma

    Not yet reported Shanghai Jiatan Pharmatech Co., Ltd 82 participants Est. completion 2020-07-25 1 site
    Other conditions: Advanced Cancer
    View official trial listing →
  • Completed NCT NCT03730428

    Everolimus Related Pneumonitis in MBC

    Fudan University 86 participants Est. completion 2020-06-15 1 site
    Other conditions: Everolimus, Pneumonitis
    View official trial listing →
  • Completed NCT NCT03732248

    Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders

    Not yet reported Medical University of South Carolina 21 participants Est. completion 2020-01-20 1 site
    Alcohol use disorder
    View official trial listing →
  • Terminated NCT NCT03740100

    Single-arm Study With Bimiralisib in Patients With HNSCC Harboring NOTCH1 Loss of Function Mutations

    Not yet reported M.D. Anderson Cancer Center 8 participants Est. completion 2020-12-09 1 site
    Other conditions: HNSCC
    View official trial listing →
  • Active, not recruiting NCT NCT03740334

    Ribociclib in Combination With Everolimus and Dexamethasone in Relapsed ALL

    Not yet reported Dana-Farber Cancer Institute 45 participants Est. completion 2027-04-30 12 sites
    Other conditions: Acute Lymphoblastic Leukemia ALL
    View official trial listing →
  • Withdrawn NCT NCT03747328

    ABI-009 (Nab-sirolimus) in Patients With Genetically-confirmed Leigh or Leigh-like Syndrome

    Not yet reported Aadi Bioscience, Inc. Est. completion 2025-03-31 Stand-alone
    Other conditions: Leigh Syndrome
    View official trial listing →
  • Completed NCT NCT03765944

    Bioequivalence Study of NPC-12 (Sirolimus) Granules and Tablets

    Not yet reported Nobelpharma 10 participants Est. completion 2018-12-29 1 site
    Other conditions: Bioequivalence Study
    View official trial listing →
  • Status unknown NCT NCT03767660

    Efficacy of Rapamycin (Sirolimus) in the Treatment of BRBNS, Hereditary or Sporadic Venous Malformation

    Not yet reported Peking Union Medical College Hospital 20 participants Est. completion 2022-07-01 1 site
    Other conditions: Blue Rubber Bleb Nevus Syndrome, Venous Malformation
    View official trial listing →
  • Active, not recruiting NCT NCT03778996

    SM-88 Maintenance Therapy for Advanced Ewing's Sarcoma and as Salvage Therapy for Sarcoma

    Not yet reported Sarcoma Oncology Research Center, LLC 31 participants Est. completion 2028-03-31 1 site Stand-alone
    Other conditions: Sarcoma, Ewing, Sarcoma
    View official trial listing →
  • Status unknown NCT NCT03780192

    INSPIRON Sirolimus Eluting Stent Performance in Bifurcation Coronary Arteries Treated Using Provisional Technique

    Scitech Produtos Medicos SA 80 participants Est. completion 2022-02-15 1 site
    Cardiovascular disease Other conditions: Bifurcation Lesion
    View official trial listing →
  • Status unknown NCT NCT03781050

    Efficacy of Rapamycin (Sirolimus) in the Treatment of Peutz-Jeghers Syndrome

    Not yet reported Peking Union Medical College Hospital 10 participants Est. completion 2022-07-01 1 site
    Other conditions: Peutz-Jeghers Syndrome
    View official trial listing →
  • Status unknown NCT NCT03785431

    Vascular Healing After Implantation of FANTOM Bioresorbable Scaffold in STEMI: A FANTOM STEMI Study

    Not yet reported Medical University of Warsaw 20 participants Est. completion 2022-06-06 1 site
    Cardiovascular disease Other conditions: STEMI, Bioresorbable Scaffold
    View official trial listing →
  • Active, not recruiting NCT NCT03797196

    RCT Comparing Immunosuppressive Regimens in Elderly Renal Transplant Recipients

    Not yet reported University Medical Center Groningen 374 participants Est. completion 2026-12 7 sites
    Other conditions: Renal Transplant Recipients, Elderly Patients, Immunosuppression
    View official trial listing →
  • Status unknown NCT NCT03805399

    FUSCC Refractory TNBC Umbrella (FUTURE)

    Not yet reported, Not yet reported Fudan University 140 participants Est. completion 2022-12-01 1 site
    Other conditions: Triple-negative Breast Cancer
    View official trial listing →
  • Approved For Marketing NCT NCT03817515

    Expanded Access for ABI-009 in Patients With Advanced PEComa and Patients With a Malignancy With Relevant Genetic Mutations or mTOR Pathway Activation

    Aadi Bioscience, Inc.
    Other conditions: PEComa, Malignant, TSC1, TSC2, mTOR Pathway Abberation
    View official trial listing →
  • Completed NCT NCT03826628

    Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

    Not yet reported, Not yet reported Dermatology Specialties Limited Partnership 107 participants Est. completion 2022-09-01 17 sites
    Other conditions: Facial Angiofibroma, Tuberous Sclerosis
    View official trial listing →
  • Completed NCT NCT03834740

    A Phase 0/I Study of Ribociclib (LEE011) in Combination With Everolimus in Preoperative Recurrent High-Grade Glioma Patients Scheduled for Resection

    Not yet reported St. Joseph's Hospital and Medical Center, Phoenix 27 participants Est. completion 2022-02-18 3 sites
    Other conditions: Glioblastoma Multiforme, Glioma of Brain
    View official trial listing →
  • Terminated NCT NCT03839940

    Dexamethasone in Reducing Everolimus-Induced Oral Stomatitis in Patients With Cancer

    Not yet reported Alliance for Clinical Trials in Oncology 39 participants Est. completion 2022-08-03 319 sites
    Other conditions: Malignant Neoplasm
    View official trial listing →
  • Status unknown NCT NCT03842813

    Safety and Performance Assessment of Drug-Eluting Stent CRE8 in Diabetic Patients

    Alvimedica Medical Technologies France 1030 participants Est. completion 2022-07 22 sites
    Other conditions: Diabetes, Coronaropathy
    View official trial listing →
  • Status unknown NCT NCT03866681

    Sirolimus Combined With Low-dose Warfarin for the Treatment of Refractory PNH

    Not yet reported Peking Union Medical College Hospital 40 participants Est. completion 2022-04-01 1 site Stand-alone
    Other conditions: Paroxysmal Nocturnal Hemoglobinuria
    View official trial listing →
  • Completed NCT NCT03871127

    Ten-Year Outcomes of PRE-COMBAT Trial

    Seung-Jung Park 600 participants Est. completion 2020-02-24 9 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT03871361

    Abatacept in Patients With Birdshot HLA A29 Uveitis

    Not yet reported Universitaire Ziekenhuizen KU Leuven 15 participants Est. completion 2023-12-01 1 site Stand-alone
    Other conditions: Eye Diseases, Uveitis
    View official trial listing →
  • Completed NCT NCT03871972

    Umbilical Cord Blood Transfusion in Progeria Syndrome

    Not yet reported, Not yet reported Bundang CHA Hospital 2 participants Est. completion 2020-06-01 1 site Stand-alone
    Other conditions: Hutchinson-Gilford Progeria Syndrome
    View official trial listing →
  • Completed NCT NCT03877809

    Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients

    Not yet reported Rare Partners srl Impresa Sociale 26 participants Est. completion 2022-04-30 2 sites Stand-alone
    Other conditions: Beta-Thalassemia
    View official trial listing →
  • Terminated NCT NCT03878524

    Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

    Not yet reported OHSU Knight Cancer Institute 2 participants Est. completion 2020-12-10 1 site Stand-alone
    Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Anatomic Stage IV Breast Cancer AJCC v8, Anemia, Ann Arbor Stage III Hodgkin Lymphoma, Ann Arbor Stage III Non-Hodgkin Lymphoma, Ann Arbor Stage IV Hodgkin Lymphoma, Ann Arbor Stage IV Non-Hodgkin Lymphoma, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Castration-Resistant Prostate Carcinoma, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid System Neoplasm, Locally Advanced Pancreatic Adenocarcinoma, Metastatic Breast Carcinoma, Metastatic Malignant Solid Neoplasm, Metastatic Pancreatic Adenocarcinoma, Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Primary Myelofibrosis, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Hematologic Malignancy, Recurrent Hodgkin Lymphoma, Recurrent Myelodysplastic Syndrome, Recurrent Myelodysplastic/Myeloproliferative Neoplasm, Recurrent Myeloproliferative Neoplasm, Recurrent Non-Hodgkin Lymphoma, Recurrent Plasma Cell Myeloma, Recurrent Small Lymphocytic Lymphoma, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Chronic Lymphocytic Leukemia, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Chronic Myelomonocytic Leukemia, Refractory Hematologic Malignancy, Refractory Hodgkin Lymphoma, Refractory Malignant Solid Neoplasm, Refractory Myelodysplastic Syndrome, Refractory Myelodysplastic/Myeloproliferative Neoplasm, Refractory Non-Hodgkin Lymphoma, Refractory Plasma Cell Myeloma, Refractory Primary Myelofibrosis, Refractory Small Lymphocytic Lymphoma, Stage II Pancreatic Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8, Unresectable Pancreatic Adenocarcinoma
    View official trial listing →
  • Status unknown NCT NCT03886233

    Treatment Outcome of Uveitis in Autoimmune Diseases

    Assiut University 1 participants Est. completion 2021-02
    Other conditions: Autoimmune Uveitis
    View official trial listing →
  • Status unknown NCT NCT03901001

    Adjunctive Sirolimus and Oseltamivir Versus Oseltamivir Alone for Treatment of Influenza

    Not yet reported Chinese University of Hong Kong 160 participants Est. completion 2025-12-31 1 site
    Other conditions: Influenza
    View official trial listing →
  • Completed NCT NCT03908450

    Treatment of Coronary De-novo Stenosis by a Sirolimus Coated Balloon or a Paclitaxel Coated Balloon Catheter

    Not yet reported InnoRa GmbH 70 participants Est. completion 2023-07-31 4 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT03910452

    Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 4 participants Est. completion 2034-06-15 1 site Stand-alone
    Other conditions: Chronic Granulomatous Disease
    View official trial listing →
  • Status unknown NCT NCT03913832

    TReAtmeNt of Small Coronary Vessels: MagicTouch Sirolimus Coated Balloon

    Not yet reported Concept Medicals BV 121 participants Est. completion 2023-09-10 6 sites Stand-alone
    Cardiovascular disease Other conditions: DCB
    View official trial listing →
  • Status unknown NCT NCT03916432

    HELIOS China Registry: Evaluation of the HELIOS Stent in a 'Real-World' Patient Population

    Not yet reported Xijing Hospital 3000 participants Est. completion 2025-12-01 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT03918070

    Observatory to Assess the Yukon Choice PC & the Yukon Chrome PC Sirolimus Eluting Bioabsorbable Polymer Stents Systems

    Translumina GmbH 2722 participants Est. completion 2024-05-24 19 sites
    Other conditions: Coronaropathy
    View official trial listing →
  • Active, not recruiting NCT NCT03922724

    Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

    Not yet reported National Cancer Institute (NCI) 91 participants Est. completion 2030-10-31 2 sites Stand-alone
    Other conditions: Peripheral T-cell Lymphomas, Lymphoproliferative Disorders, Immune System Diseases
    View official trial listing →
  • Status unknown NCT NCT03932539

    Improving Immunosuppressive Therapy in Heart Transplantation

    Fondazione IRCCS Policlinico San Matteo di Pavia 25 participants Est. completion 2021-12 4 sites
    Other conditions: Rejection Heart Transplant, Immunosuppression
    View official trial listing →
  • Active, not recruiting NCT NCT03933904

    Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease

    Not yet reported University of Pennsylvania 7 participants Est. completion 2027-06-30 2 sites Stand-alone
    Other conditions: Castleman Disease, Castleman's Disease, Multicentric
    View official trial listing →
  • Terminated NCT NCT03942601

    Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization

    Not yet reported Mercator MedSystems, Inc. 10 participants Est. completion 2021-04-30 11 sites
    Other conditions: Peripheral Arterial Disease
    View official trial listing →
  • Status unknown NCT NCT03942926

    The Efficacy and Safety of Sirolimus for Plastic Bronchitis

    Not yet reported Peking Union Medical College Hospital 10 participants Est. completion 2020-05-05 1 site Stand-alone
    Other conditions: Plastic Bronchitis
    View official trial listing →
  • Terminated NCT NCT03946774

    Dietary Protein and Monocyte/Macrophage Mammalian Target of Rapamycin (mTOR) Signaling

    Not yet reported Washington University School of Medicine 21 participants Est. completion 2023-05-04 1 site
    Other conditions: Dietary Protein
    View official trial listing →
  • Active, not recruiting NCT NCT03950609

    Lenvatinib and Everolimus in Treating Patients With Advanced, Unresectable Carcinoid Tumors

    Not yet reported M.D. Anderson Cancer Center 36 participants Est. completion 2028-03-30 1 site
    Other conditions: Advanced Carcinoid Tumor, Digestive System Neuroendocrine Neoplasm, Multiple Endocrine Neoplasia Type 1, Neuroendocrine Neoplasm, Unresectable Carcinoid Tumor
    View official trial listing →
  • Active, not recruiting NCT NCT03952273

    Sort Out XI - Combo Stent Versus BioMatrix Alpha Stent

    Not yet reported Phillip Freeman 3141 participants Est. completion 2030-11-30 2 sites
    Cardiovascular disease
    View official trial listing →
  • Terminated NCT NCT03963024

    Treosulfan-TMI Conditioning and Rapamycin GvHD Prophylaxis Before Allo-HSCT

    Not yet reported IRCCS San Raffaele 9 participants Est. completion 2019-01-31 1 site
    Other conditions: Irradiated Bone Marrow, Transplant-Related Hematologic Malignancy, Leukemia, Acute, Multiple Myeloma, Graft Vs Host Disease
    View official trial listing →
  • Completed NCT NCT03972462

    NPC-12G Gel 0.2% Sirolimus PK Bridging Study

    Not yet reported Nobelpharma 12 participants Est. completion 2019-06-17 1 site Stand-alone
    Other conditions: Bioavailability Study
    View official trial listing →
  • Completed NCT NCT03972592

    Topical Sirolimus in Cutaneous Lymphatic Malformations

    Not yet reported University Hospital, Tours 55 participants Est. completion 2024-08-14 17 sites Stand-alone
    Other conditions: Vascular Malformations, Lymphatic Malformation
    View official trial listing →
  • Active, not recruiting NCT NCT03983850

    Optimizing PTCy Dose and Timing

    Not yet reported, Not yet reported National Cancer Institute (NCI) 105 participants Est. completion 2026-10-26 1 site Stand-alone
    Other conditions: Graft Versus Host Disease, Hematologic Neoplasms
    View official trial listing →
  • Status unknown NCT NCT03987152

    Treatment of Congenital Vascular Malformations Using Sirolimus: Improving Quality of Life

    Not yet reported Radboud University Medical Center 75 participants Est. completion 2023-03-01 1 site
    Other conditions: Vascular Malformations
    View official trial listing →
  • Status unknown NCT NCT04014595

    PREPARE-CALC-COMBO: Severely Calcified Coronary Lesions Prepared With Rotational Atherectomy and Modified Balloons

    Segeberger Kliniken GmbH 100 participants Est. completion 2025-07-31 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT04017364

    Treatment of Coronary De-novo Stenosis by a Sirolimus Coated Balloon or a Paclitaxel Coated Balloon Catheter Malaysia

    Not yet reported InnoRa GmbH 70 participants Est. completion 2021-01-31 6 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT04047576

    Study of Sirolimus in Idiopathic Retroperitoneal Fibrosis

    Not yet reported, Not yet reported Peking University International Hospital 64 participants Est. completion 2026-06-28 1 site Stand-alone
    Other conditions: Retroperitoneal Fibrosis
    View official trial listing →
  • Completed NCT NCT04049552

    RAPA-Keloid Study of Keloid Regression

    Not yet reported The University of Texas Health Science Center at San Antonio 4 participants Est. completion 2021-05-02 1 site
    Other conditions: Keloid
    View official trial listing →
  • Completed NCT NCT04066114

    Treg Modulation With CD28 and IL-6 Receptor Antagonists

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 24 participants Est. completion 2023-09-14 7 sites
    Other conditions: Living-Donor Kidney Transplant, Kidney Transplant Recipients
    View official trial listing →
  • Completed NCT NCT04071782

    Investigating the Safety and Efficacy of the Treatment With the Selution Sirolimus Coated Balloon in TASC C and D Tibial Occlusive Disease in Patients With Critical Limb Ischemia From Singapore

    Not yet reported Singapore General Hospital 25 participants Est. completion 2021-01-30 1 site Stand-alone
    Other conditions: Critical Limb Ischemia
    View official trial listing →
  • Completed NCT NCT04077515

    Safety and Efficacy of Low-dose Sirolimus to Kaposiform Hemangioendothelioma

    Not yet reported Children's Hospital of Fudan University 92 participants Est. completion 2022-12-31 1 site Stand-alone
    Other conditions: Hemangioma, Kaposiform Hemangioendothelioma
    View official trial listing →
  • Completed NCT NCT04094675

    Sirolimus for Cowden Syndrome With Colon Polyposis

    Not yet reported Ohio State University 5 participants Est. completion 2025-06-05 1 site Stand-alone
    Other conditions: PTEN Gene Mutation, PTEN Hamartoma Tumor Syndrome, PTEN Hamartoma Syndrome, Cowden Syndrome, Bannayan Syndrome, Bannayan Zonana Syndrome, Polyposis
    View official trial listing →
  • Completed NCT NCT04104438

    Examination of Immunosuppression Adjustment Impact on Kidney Function in Liver Transplant

    Not yet reported Fady M Kaldas, M.D., F.A.C.S. 71 participants Est. completion 2024-09-30 1 site
    Other conditions: Asses Immunosuppression Modulation on Renal Recovery Post LT
    View official trial listing →
  • Completed NCT NCT04107298

    Safety and Feasibility of Surmodics SUNDANCE™ Drug Coated Balloon

    Not yet reported SurModics, Inc. 35 participants Est. completion 2024-01-30 8 sites Stand-alone
    Other conditions: Peripheral Arterial Disease, Critical Lower Limb Ischemia
    View official trial listing →
  • Completed NCT NCT04115800

    Liposomal Sirolimus in Dry Eye Disease

    Not yet reported Instituto de Oftalmología Fundación Conde de Valenciana 52 participants Est. completion 2020-08-01 1 site Stand-alone
    Other conditions: Dry Eye
    View official trial listing →
  • Terminated NCT NCT04118556

    Decidua Stroma Cells for Steroid Resistent Acute Graft-versus-host Disease After Allo-HSCT

    Not yet reported Mats Remberger 12 participants Est. completion 2026-04-29 4 sites
    Other conditions: GVHD, Acute
    View official trial listing →
  • Active, not recruiting NCT NCT04127578

    Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)

    Not yet reported, Not yet reported Prevail Therapeutics 32 participants Est. completion 2031-08-31 15 sites Stand-alone
    Other conditions: Parkinson Disease
    View official trial listing →
  • Completed NCT NCT04128722

    TOPical Sirolimus in linGUal Microcystic Lymphatic Malformation -TOPGUN

    Not yet reported University Hospital, Tours 12 participants Est. completion 2025-01-08 2 sites Stand-alone
    Other conditions: Lingual Microcystic Lymphatic Malformations
    View official trial listing →
  • Status unknown NCT NCT04135989

    Personalized Vs. Standard Duration of Dual Antiplatelet Therapy and New-generation Polymer-Free vs- Biodegradable-Polymer DES

    Not yet reported Federico II University 2106 participants Est. completion 2024-10-24 13 sites
    Cardiovascular disease Other conditions: Acute Coronary Syndrome, Chronic Coronary Syndrome
    View official trial listing →
  • Completed NCT NCT04138238

    Cruz HBR Registry - Post-market Registry to Evaluate the Safety and Efficacy of the Supraflex Cruz Stent

    Sahajanand Medical Technologies Limited 1200 participants Est. completion 2022-05-31 26 sites
    Cardiovascular disease
    View official trial listing →
  • Withdrawn NCT NCT04139915

    Effect of RTB101 on Illness Associated With Respiratory Tract Infections in the Elderly

    Not yet reported Restorbio Inc. Est. completion 2019-11-15
    Other conditions: Clinically Symptomatic Respiratory Illness
    View official trial listing →
  • Status unknown NCT NCT04150016

    In-stent Repair and Vessel Reaction of STEMI Patients With OCT

    Not yet reported Xijing Hospital 44 participants Est. completion 2021-12-01 1 site Stand-alone
    Cardiovascular disease Other conditions: Drug-eluting Stents, Percutaneous Coronary Intervention, Optical Coherence Tomography
    View official trial listing →
  • Active, not recruiting NCT NCT04157153

    First in Men Study: BIOMAG-I

    Not yet reported Biotronik AG 116 participants Est. completion 2027-02 14 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT04161144

    Enhancing Self Regulation Among Smokers

    Not yet reported Medical University of South Carolina 22 participants Est. completion 2019-12-20 1 site
    Other conditions: Smoking Cessation, Smoking, Cigarette, Nicotine Dependence
    View official trial listing →
  • Status unknown NCT NCT04168944

    Lenvatinib Following Liver Transplantation in Patients With High-Risk Hepatocellular Carcinoma

    Not yet reported, Not yet reported RenJi Hospital 108 participants Est. completion 2022-09 Stand-alone
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Terminated NCT NCT04172922

    Topical Rapamycin/Sirolimus for Complicated Vascular Anomalies and Other Susceptible Lesions

    Not yet reported Nemours Children's Clinic 5 participants Est. completion 2024-02-15 2 sites Stand-alone
    Other conditions: Vascular Anomaly
    View official trial listing →
  • Completed NCT NCT04175626

    Safety and Effectiveness of the Orsiro Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

    Biotronik, Inc. 556 participants Est. completion 2026-01-08 33 sites
    Cardiovascular disease Other conditions: Atherosclerosis, Coronary, Myocardial Ischemia, Ischemic Heart Disease, Acute Coronary Syndrome, Angina Pectoris
    View official trial listing →
  • Completed NCT NCT04176380

    RAPA-201 T Cell Therapy for Relapsed, Refractory Multiple Myeloma

    Not yet reported Rapa Therapeutics LLC 15 participants Est. completion 2023-06-06 1 site
    Other conditions: Relapsed, Refractory Multiple Myeloma
    View official trial listing →
  • Active, not recruiting NCT NCT04177004

    Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

    Not yet reported City of Hope Medical Center 52 participants Est. completion 2026-10-27 1 site Stand-alone
    Other conditions: Allogeneic Hematopoietic Stem Cell Transplant Recipient, Hematopoietic and Lymphoid Cell Neoplasm
    View official trial listing →
  • Completed NCT NCT04177095

    Immune Monitoring to Facilitate Belatacept Monotherapy

    Not yet reported Massachusetts General Hospital 17 participants Est. completion 2023-06-01 1 site Stand-alone
    Other conditions: Kidney Transplant Rejection, Immunosuppression
    View official trial listing →
  • Status unknown NCT NCT04179045

    A Registry Trial of The Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System

    Not yet reported Shanghai Bio-heart Biological Technology Co., Ltd. 785 participants Est. completion 2026-07 5 sites
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT04185831

    A MolEcularly Guided Anti-Cancer Drug Off-Label Trial

    Not yet reported Uppsala University Hospital 167 participants Est. completion 2024-10 3 sites
    Other conditions: Solid Tumor
    View official trial listing →
  • Active, not recruiting NCT NCT04185883

    Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

    Not yet reported Amgen 610 participants Est. completion 2027-12-05 90 sites
    Other conditions: Advanced Solid Tumors, Kirsten Rat Sarcoma (KRAS) pG12C Mutation
    View official trial listing →
  • Active, not recruiting NCT NCT04188548

    A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer

    Not yet reported Eli Lilly and Company 379 participants Est. completion 2027-12 74 sites
    Other conditions: Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer, Endometrial Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT04192747

    The Elixir Bioadaptor vs. The Onyx Stent in De Novo Native Coronary Arteries

    Not yet reported Elixir Medical Corporation 445 participants Est. completion 2027-02-28 36 sites
    Cardiovascular disease Other conditions: Coronary Artery Stenosis, Coronary Disease, Coronary Stenosis
    View official trial listing →
  • Active, not recruiting NCT NCT04195750

    A Study of Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005)

    Not yet reported Merck Sharp & Dohme LLC 755 participants Est. completion 2026-09-17 172 sites
    Other conditions: Carcinoma, Renal Cell
    View official trial listing →
  • Completed NCT NCT04200911

    Cognition, Age, and RaPamycin Effectiveness - DownregulatIon of thE mTor Pathway

    Not yet reported The University of Texas Health Science Center at San Antonio 10 participants Est. completion 2022-01-13 1 site Stand-alone
    Other conditions: Cognitive Impairment, Mild, Alzheimer Disease
    View official trial listing →
  • Completed NCT NCT04202172

    Functional Assessment of the Infart-related Artery With Bioactive and Polymer-free Coronary Stents (The FUNCOMBO Trial)

    Not yet reported Institut d'Investigació Biomèdica de Bellvitge 60 participants Est. completion 2020-09-01 1 site
    Cardiovascular disease Other conditions: Endothelial Dysfunction, Coronary Microvascular Disease
    View official trial listing →
  • Terminated NCT NCT04203901

    Dendritic Cell Immunotherapy Plus Standard Treatment of Advanced Renal Cell Carcinoma

    Not yet reported CoImmune 16 participants Est. completion 2023-09-28 9 sites
    Other conditions: Advanced Renal Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT04212702

    ESR1 Mutations in Asian ER+ Metastatic Breast Cancer on Hormonal Therapy-based Treatments

    National Taiwan University Hospital 123 participants Est. completion 2021-12-31 2 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT04229004

    A Multi-center Trial to Evaluate Multiple Regimens in Metastatic Pancreatic Cancer

    Not yet reported Pancreatic Cancer Action Network 502 participants Est. completion 2025-02-05 25 sites Stand-alone
    Other conditions: Metastatic Pancreatic Cancer, Metastatic Pancreatic Adenocarcinoma
    View official trial listing →
  • Active, not recruiting NCT NCT04230499

    Trial of ERapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance

    Not yet reported Rapamycin Holdings Inc. 30 participants Est. completion 2025-03 4 sites
    Other conditions: Familial Adenomatous Polyposis
    View official trial listing →
  • Status unknown NCT NCT04236609

    Randomized Comparison of Abluminus DES+ Sirolimus-Eluting Stents Versus Everolimus-Eluting Stents in Coronary Artery Disease Patients With Diabetes Mellitus Global

    Not yet reported Concept Medical Inc. 3050 participants Est. completion 2024-09-30 90 sites
    Cardiovascular disease Other conditions: Diabetes, Acute Coronary Syndrome
    View official trial listing →
  • Active, not recruiting NCT NCT04238546

    Major Adverse Limb Events in Patients With Femoro-popliteal and Below-the-knee Peripheral Arterial Disease Treated With Either Sirolimus-coated Balloon or Standard Uncoated Balloon Angioplasty

    Not yet reported Nils Kucher 1200 participants Est. completion 2029-12-31 2 sites Stand-alone
    Other conditions: Peripheral Arterial Disease
    View official trial listing →
  • Completed NCT NCT04240444

    Sirolimus-Coated Balloon Versus Paclitaxel-Coated Balloon for the Treatment of Coronary In-Stent Restenosis

    Not yet reported B. Braun Medical International Trading Company Ltd. 260 participants Est. completion 2022-08-30 16 sites Stand-alone
    Cardiovascular disease Other conditions: In Stent Restenosis
    View official trial listing →
  • Status unknown NCT NCT04247750

    Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients (THALA-RAP)

    Not yet reported Università degli Studi di Ferrara 45 participants Est. completion 2022-04-30 4 sites Stand-alone
    Other conditions: Beta-Thalassemia
    View official trial listing →
  • Terminated NCT NCT04258423

    Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function

    Not yet reported Indiana University 4 participants Est. completion 2020-06-27 1 site
    Other conditions: Kidney Failure
    View official trial listing →
  • Active, not recruiting NCT NCT04280029

    SELUTION SLR™ 014 In-stent Restenosis

    Not yet reported M.A. Med Alliance S.A. 418 participants Est. completion 2029-08 48 sites Stand-alone
    Other conditions: Coronary Restenosis
    View official trial listing →
  • Terminated NCT NCT04305444

    Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas

    Not yet reported Zhejiang DTRM Biopharma 55 participants Est. completion 2024-12-31 8 sites
    Other conditions: Relapsed Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, Richter's Transformation
    View official trial listing →
  • Completed NCT NCT04323033

    Safety and Efficacy of Peripheral, Cobalt-chromium Sirolimus Eluting Stent (PERS) Versus Cobalt-chromium Stent (Neptune C)

    Not yet reported Balton Sp.zo.o. 40 participants Est. completion 2021-11-09 3 sites Stand-alone
    Other conditions: Peripheral Arterial Disease
    View official trial listing →
  • Completed NCT NCT04324372

    Clinical Study of HEC68498 in Patients With Advanced Refractory Solid Tumors

    Not yet reported Sunshine Lake Pharma Co., Ltd. 12 participants Est. completion 2021-03-26 1 site
    Other conditions: Advanced Refractory Solid Tumors
    View official trial listing →
  • Withdrawn NCT NCT04324411

    Sirolimus Combined With ATRA for the Treatment of Auto-Immune Anemia

    Not yet reported Peking Union Medical College Hospital Est. completion 2023-09-01 1 site Stand-alone
    Other conditions: Autoimmune Anemia
    View official trial listing →
  • Completed NCT NCT04327609

    SAVE Trial - Use of the Selution Sirolimus Eluting Balloon for Dysfunctional AV accEss Treatment Indications

    Not yet reported M.A. Med Alliance S.A. 84 participants Est. completion 2025-07-23 3 sites Stand-alone
    Other conditions: AV Fistula
    View official trial listing →
  • Completed NCT NCT04339062

    Cemiplimab in AlloSCT/SOT Recipients With CSCC

    Not yet reported, Not yet reported Dana-Farber Cancer Institute 12 participants Est. completion 2025-03-01 1 site Stand-alone
    Other conditions: Cutaneous Squamous Cell Carcinoma, Advanced Cancer
    View official trial listing →
  • Completed NCT NCT04339101

    Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation

    Not yet reported City of Hope Medical Center 59 participants Est. completion 2025-10-09 1 site Stand-alone
    Other conditions: Acute Leukemia, Hematologic and Lymphocytic Disorder, Myelodysplastic Syndrome, Primary Myelofibrosis, Secondary Myelofibrosis
    View official trial listing →
  • Completed NCT NCT04341675

    Sirolimus Treatment in Hospitalized Patients With COVID-19 Pneumonia

    Not yet reported University of Cincinnati 32 participants Est. completion 2020-09-15 2 sites
    Other conditions: COVID-19
    View official trial listing →
  • Status unknown NCT NCT04345965

    Sirolimus Eluting Balloon Utilization for Treatment of Vasculogenic Erectile Dysfunction

    Clinica San Gaudenzio 100 participants Est. completion 2023-12-01 1 site
    Other conditions: Erectile Dysfunction
    View official trial listing →
  • Terminated NCT NCT04348292

    Sirolimus and Durvalumab for the Treatment of Stage I-IIIA Non-small Cell Lung Cancer

    Not yet reported Emory University 3 participants Est. completion 2022-11-04 1 site Stand-alone
    Other conditions: Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8, Stage IA3 Lung Cancer AJCC v8, Stage IB Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8
    View official trial listing →
  • Status unknown NCT NCT04355858

    Molecularly Targeted Umbrella Study in Luminal Advanced Breast Cancer

    Not yet reported Fudan University 319 participants Est. completion 2025-04-01 1 site
    Other conditions: Breast Cancer, Metastatic Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT04362293

    Reduced Intensity Transplantation for Severe Sickle Cell Disease

    Not yet reported St. Jude Children's Research Hospital 46 participants Est. completion 2029-08-01 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Completed NCT NCT04368091

    Clinical Use and Safety of the Xtreme Touch (Magic Touch PTA)- Neo Sirolimus Coated PTA Balloon Catheter in the Treatment of Infrainguinal Peripheral Arterial Disease

    Concept Medical Inc. 50 participants Est. completion 2021-12-30 1 site
    Other conditions: Peripheral Artery Disease, Atherosclerosis
    View official trial listing →
  • Withdrawn NCT NCT04370795

    Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning With h-ATG, Radiation, and Sirolimus

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) Est. completion 2025-11-26 1 site
    Other conditions: Severe Combined Immune Deficiency (SCID)
    View official trial listing →
  • Withdrawn NCT NCT04371640

    Sirolimus in COVID-19 Phase 1

    Not yet reported Walter K. Kraft Est. completion 2021-07-30 1 site
    Other conditions: SARS-CoV-2, Covid-19
    View official trial listing →
  • Withdrawn NCT NCT04374903

    Hydroxychloroquine in Combination With Sirolimus and Dexamethasone for Treating COVID-19 Patients

    Not yet reported King Hussein Cancer Center Est. completion 2022-04-01 1 site Stand-alone
    Other conditions: COVID-19 Patients
    View official trial listing →
  • Active, not recruiting NCT NCT04375813

    Trial of Encapsulated Rapamycin (eRapa) for Bladder Cancer Prevention

    Not yet reported Robert Svatek 166 participants Est. completion 2027-07 2 sites
    Other conditions: Non-muscle Invasive Bladder Cancer
    View official trial listing →
  • Completed NCT NCT04388371

    Glutamine PET Imaging in LAM

    Not yet reported Vanderbilt University Medical Center 5 participants Est. completion 2021-08-10 1 site Stand-alone
    Other conditions: Lymphangioleiomyomatosis (LAM)
    View official trial listing →
  • Active, not recruiting NCT NCT04390672

    Multivessel TALENT

    Not yet reported National University of Ireland, Galway, Ireland 1550 participants Est. completion 2026-09 1 site Stand-alone
    Cardiovascular disease Other conditions: Myocardial Ischemia, Coronary Disease, Heart Diseases, Arterial Occlusive Diseases, Vascular Diseases
    View official trial listing →
  • Terminated NCT NCT04393454

    Study to Evaluate the Efficacy and Safety of Sirolimus in Subjects With Metastatic, Mismatch Repair Deficient Solid Tumors After Immunotherapy

    Not yet reported Albert Einstein College of Medicine 6 participants Est. completion 2023-05-16 1 site Stand-alone
    Other conditions: Metastatic dMMR Solid Cancer, Solid Tumor, Cancer, Metastatic Solid Tumor
    View official trial listing →
  • Status unknown NCT NCT04406870

    Sirolimus in the Treatment for Infantile Hepatic Hemangioendothelioma(IEEH)

    Not yet reported Shanghai Children's Medical Center 36 participants Est. completion 2025-06-30 1 site Stand-alone
    Other conditions: Hemangioendothelioma of Liver
    View official trial listing →
  • Active, not recruiting NCT NCT04408625

    Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

    Not yet reported, Not yet reported Prevail Therapeutics 35 participants Est. completion 2029-11-30 12 sites Stand-alone
    Other conditions: Frontotemporal Dementia
    View official trial listing →
  • Terminated NCT NCT04409327

    Phase 2 Study to Determine if RTB101 Reduces the Severity of COVID-19 in Older Adults Residing in Nursing Homes

    Not yet reported Restorbio Inc. 36 participants Est. completion 2021-01-24 1 site
    Other conditions: COVID19
    View official trial listing →
  • Status unknown NCT NCT04409691

    SCMC Trial on KHE With KMP (V.2020)

    Not yet reported Shanghai Children's Medical Center 20 participants Est. completion 2023-06-30 1 site Stand-alone
    Other conditions: Kaposiform Hemangioendothelioma (KHE) With Kasabach-Merritt Phenomenon (KMP)
    View official trial listing →
  • Status unknown NCT NCT04409912

    Sirolimus Coated Angioplasty Versus Plain Balloon Angioplasty

    Not yet reported Singapore General Hospital 170 participants Est. completion 2024-10 3 sites Stand-alone
    Other conditions: End Stage Renal Failure on Dialysis, Arteriovenous Graft Occlusion
    View official trial listing →
  • Active, not recruiting NCT NCT04411654

    Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)

    Not yet reported, Not yet reported Prevail Therapeutics 7 participants Est. completion 2027-02 6 sites Stand-alone
    Other conditions: Gaucher Disease, Type 2
    View official trial listing →
  • Withdrawn NCT NCT04415476

    Standard Therapy Using Tacrolimus, Mycophenolate Mofetil and Prednisone For Chronic Lung Transplant Rejection (BOS)

    Not yet reported University of Maryland, Baltimore Est. completion 2028-06-30 Stand-alone
    Other conditions: Disorder Related to Lung Transplantation, Chronic Rejection of Lung Transplant, Decreased Immunologic Activity
    View official trial listing →
  • Completed NCT NCT04448873

    Guided Discontinuation Versus Maintenance Treatment of Sirolimus in Pediatric Patients With Kaposiform Hemangioendothelioma

    Not yet reported Children's Hospital of Fudan University 30 participants Est. completion 2023-07-01 1 site Stand-alone
    Other conditions: Kaposiform Hemangioendothelioma, Kasabach-Merritt Syndrome
    View official trial listing →
  • Status unknown NCT NCT04461340

    Efficacy and Safety of Sirolimus in COVID-19 Infection

    Not yet reported Alexandria University 40 participants Est. completion 2020-11-30 1 site Stand-alone
    Other conditions: COVID 19
    View official trial listing →
  • Terminated NCT NCT04461886

    A Long-term Study of NPC-12G Gel in Neurofibromatosis Type I

    Not yet reported Nobelpharma 100 participants Est. completion 2021-12-07 4 sites Stand-alone
    Other conditions: Neurofibromatosis
    View official trial listing →
  • Completed NCT NCT04470804

    Sirolimus Treatment for Newly Diagnosed Primary Acquired PRCA

    Not yet reported Bing Han 56 participants Est. completion 2022-07-31 1 site Stand-alone
    Other conditions: Pure Red Cell Aplasia, Acquired
    View official trial listing →
  • Active, not recruiting NCT NCT04470934

    SeQuent® SCB "All Comers" Post Market Clinical Follow-up (PMCF)

    B. Braun Melsungen AG 1302 participants Est. completion 2027-03-31 1 site
    Cardiovascular disease Other conditions: Myocardial Ischaemia
    View official trial listing →
  • Completed NCT NCT04471441

    Efficacy and Safety of Everolimus Versus Mycophenolate Mofetil in Liver Transplant Recipients.

    Not yet reported Chong Kun Dang Pharmaceutical 150 participants Est. completion 2024-07-24 1 site
    Other conditions: Liver Transplant
    View official trial listing →
  • Completed NCT NCT04473911

    Haplo Peripheral Blood Sct In GVHD Prevention

    Not yet reported Zachariah Michael DeFilipp 25 participants Est. completion 2024-08-19 1 site Stand-alone
    Other conditions: GVHD, AML, ALL, MDS, MPN, CMML, Hodgkin Lymphoma, Non Hodgkin Lymphoma, Blood Stem Cell Transplant Failure, Graft Vs Host Disease, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorder, Chronic Myelomonocytic Leukemia, Chemosensitive Hodgkin Lymphoma
    View official trial listing →
  • Completed NCT NCT04475536

    A Prospective Study, Single-arm, Multicentre, Observational to Evaluate Safety and Effectiveness of Stent Ultimaster Tansei Coronary Stent in Complex Coronary Lesions.

    Fundación EPIC 501 participants Est. completion 2024-02-01 17 sites
    Cardiovascular disease Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Active, not recruiting NCT NCT04475783

    Sirolimus- vs. Paclitaxel-Drug Coated Ballons in Patients With Peripheral Artery Disease

    Not yet reported Jena University Hospital 478 participants Est. completion 2027-12-31 22 sites Stand-alone
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Withdrawn NCT NCT04482712

    Effects of mTOR Inhibition With Sirolimus (RAPA) in Patients With COVID-19 to Moderate the Progression of ARDS

    Not yet reported, Not yet reported The University of Texas Health Science Center at San Antonio Est. completion 2023-01 2 sites
    Other conditions: Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS), Respiratory Failure, Sars-CoV2
    View official trial listing →
  • Completed NCT NCT04488601

    Participatory Evaluation (of) Aging (With) Rapamycin (for) Longevity Study

    Not yet reported AgelessRx 129 participants Est. completion 2023-12-30 1 site
    Other conditions: Aging
    View official trial listing →
  • Status unknown NCT NCT04534257

    Prospective Registry to Investigate the Safety and Efficacy of the Treatment With the Selution Sirolimus Drug Coated Balloon in TASC C and D Atheroma-occlusive Infra-Inguinal Disease in Patients With Chronic Limb Threatening Ischemia From Singapore

    Not yet reported Singapore General Hospital 75 participants Est. completion 2022-05-20 1 site Stand-alone
    Other conditions: Critical Lower Limb Ischemia, Peripheral Artery Disease
    View official trial listing →
  • Active, not recruiting NCT NCT04542733

    The Efficacy of Everolimus With Reduced-dose Tacrolimus Versus Reduced-dose Tacrolimus and Leflunomide in Treatment of BK Virus Infection in Kidney Transplantation Recipient

    Not yet reported King Chulalongkorn Memorial Hospital 50 participants Est. completion 2028-07 1 site
    Other conditions: Kidney Transplant Infection, BK Virus Infection
    View official trial listing →
  • Active, not recruiting NCT NCT04561739

    Paclitaxel-coated Balloon for Treatment of De-novo Non-complex Coronary Artery Lesions

    Not yet reported Xijing Hospital 2272 participants Est. completion 2027-05-05 1 site
    Cardiovascular disease Other conditions: De Novo Stenosis
    View official trial listing →
  • Active, not recruiting NCT NCT04562532

    Firehawk Rapamycin Target Eluting Coronary Stent North American Trial

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 1720 participants Est. completion 2027-06-30 57 sites
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT04562740

    ABLUMINUS DES BTK Registry - FIM

    Not yet reported Concept Medical Inc. 30 participants Est. completion 2024-12-02 1 site Stand-alone
    Other conditions: Peripheral Artery Disease, Arterial Disease of Legs, Atherosclerosis
    View official trial listing →
  • Active, not recruiting NCT NCT04562805

    Infinity-Swedeheart Registry Based Randomized Clinical Trial (R-RCT)

    Not yet reported Elixir Medical Corporation 2400 participants Est. completion 2028-07-31 19 sites Stand-alone
    Cardiovascular disease Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Status unknown NCT NCT04570345

    3 Months Versus 12 Months Dual Antiplatelet Therapy After Drug-eluting Stent Implantation in STEMI

    Not yet reported Dong-A University 1002 participants Est. completion 2022-08 1 site
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT04582136

    Efficacy and Safety of Sirolimus in Active Systemic Lupus Erythematosus

    Not yet reported Chinese SLE Treatment And Research Group 146 participants Est. completion 2026-01 6 sites Stand-alone
    Other conditions: Systemic Lupus Erythematosus
    View official trial listing →
  • Active, not recruiting NCT NCT04584710

    A Phase 2 Study of RTB101 as COVID-19 Post-Exposure Prophylaxis in Older Adults

    Not yet reported Restorbio Inc. 60 participants Est. completion 2021-02 2 sites
    Other conditions: Covid19
    View official trial listing →
  • Status unknown NCT NCT04591431

    The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy

    Not yet reported Fondazione per la Medicina Personalizzata 400 participants Est. completion 2025-06 37 sites
    Other conditions: Breast Cancer, Gastrointestinal Cancer, Non Small Cell Lung Cancer, Other Cancer
    View official trial listing →
  • Status unknown NCT NCT04594889

    Comparison of Sirolimus vs Paclitaxel Drug Eluting Balloon for Below-the-knee Angioplasty in Critical Limb Ischemia

    Not yet reported Ospedale San Donato 170 participants Est. completion 2022-12-31 1 site Stand-alone
    Other conditions: Critical Limb Ischemia, Drug Effect
    View official trial listing →
  • Completed NCT NCT04595513

    Stopping TSC Onset and Progression 2: Epilepsy Prevention in TSC Infants

    Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 5 participants Est. completion 2022-12-15 1 site Stand-alone
    Other conditions: Tuberous Sclerosis Complex, Epilepsy
    View official trial listing →
  • Status unknown NCT NCT04598204

    Efficacy and Safety of Rapamycin to Complex Vascular Anomalies in Pediatric Patients

    Not yet reported, Not yet reported Zhujiang Hospital 30 participants Est. completion 2022-12-01 1 site
    Other conditions: Vascular Anomalies
    View official trial listing →
  • Status unknown NCT NCT04598815

    Sirolimus for Graves' Orbitopathy (GO)

    Not yet reported University of Pisa 54 participants Est. completion 2025-05-31 1 site Stand-alone
    Other conditions: Graves Ophthalmopathy
    View official trial listing →
  • Completed NCT NCT04608448

    Topical-RAPA Use in Inflammation Reversal and Re-setting the Epigenetic Clock

    Not yet reported The University of Texas Health Science Center at San Antonio 22 participants Est. completion 2022-04-15 1 site
    Other conditions: Aging, Epigenetics, Inflammatory Mediators
    View official trial listing →
  • Completed NCT NCT04612179

    Post-Market Registry to Evaluate the Safety and Efficacy of the The SUPRAFLEX CRUZ™ Sirolimus Eluting Coronary Stent System in the Treatment of an Octo- and Nonagenerian All-Comer Patient Cohort With Coronary Artery Disease - the Cruz Senior Study

    IHF GmbH - Institut für Herzinfarktforschung 2017 participants Est. completion 2025-06-12 1 site
    Other conditions: Coronary Disease
    View official trial listing →
  • Status unknown NCT NCT04629118

    Intervention With Selution SLR™ Agent Balloon for Endovascular Latent Limus Therapy for Failing AV Fistulas (ISABELLA) Trial

    Singapore General Hospital 40 participants Est. completion 2023-10-30 1 site
    Other conditions: Arteriovenous Fistula, Dialysis Access Malfunction
    View official trial listing →
  • Active, not recruiting NCT NCT04629495

    Rapamycin - Effects on Alzheimer's and Cognitive Health

    Not yet reported The University of Texas Health Science Center at San Antonio 40 participants Est. completion 2027-03-05 1 site
    Other conditions: Mild Cognitive Impairment, Alzheimer Disease
    View official trial listing →
  • Status unknown NCT NCT04660240

    Randomized Trial Comparing Two Sirolimus-Eluting Stents in Diabetes Mellitus

    Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 860 participants Est. completion 2025-09-01 1 site Stand-alone
    Cardiovascular disease Other conditions: Diabetes Mellitus, Acute Coronary Syndrome
    View official trial listing →
  • Status unknown NCT NCT04661254

    Treg Cell Therapy in Liver and Kidney Transplantation - Preclinical Validation of Batches of Treg Cells Amplified in Vitro

    Not yet reported Assistance Publique - Hôpitaux de Paris 4 participants Est. completion 2024-04-30 2 sites
    Other conditions: Kidney Transplantation, Liver Transplantation
    View official trial listing →
  • Completed NCT NCT04698512

    MAgicTouch™ Intervention Leap for Dialysis Access (MATILDA) Trial

    Singapore General Hospital 35 participants Est. completion 2021-01-30 1 site
    Other conditions: Dialysis Access Malfunction, End Stage Renal Failure on Dialysis, End Stage Renal Disease, Fistulas Arteriovenous, Stenosis
    View official trial listing →
  • Status unknown NCT NCT04700709

    Efficacy and Safety of Sirolimus Plus CNI Compared With MMF Plus CNI in ABO-i Kidney Transplant Recipients.

    Not yet reported Chong Kun Dang Pharmaceutical 158 participants Est. completion 2025-01 1 site Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT04707209

    Sirolimus for Retinal Astrocytic Hamartoma

    Not yet reported The Hospital for Sick Children 1 participants Est. completion 2024-03-22 1 site Stand-alone
    Other conditions: Retinal Astrocytic Hamartoma
    View official trial listing →
  • Terminated NCT NCT04720664

    Oral SM-88 in Patients With Metastatic HR+/HER2- Breast Cancer

    Not yet reported Georgetown University 11 participants Est. completion 2023-02-10 5 sites Stand-alone
    Other conditions: Breast Cancer, Metastatic Breast Cancer, Hormone Receptor Positive Breast Carcinoma
    View official trial listing →
  • Not yet recruiting NCT NCT04736589

    Inetetamab Plus Rapamycin and Chemotherapy for HER2+ Metastatic Breast Cancer With Abnormal Activation of PAM Pathway

    Not yet reported Peking Union Medical College 270 participants Est. completion 2027-02-02 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Not yet recruiting NCT NCT04736953

    Sirolimus Treatment Of Patients With SLE

    Not yet reported State University of New York - Upstate Medical University 220 participants Est. completion 2029-01-01
    Other conditions: Lupus Erythematosus, Systemic
    View official trial listing →
  • Active, not recruiting NCT NCT04742777

    Effect of mTOR Inhibition & Other Metabolism Modulating Interventions on the Elderly [SubStudy Rapa & cMRI to Evaluate Cardiac Function]

    Not yet reported The University of Texas Health Science Center at San Antonio 20 participants Est. completion 2026-10-16 2 sites
    Other conditions: Aging
    View official trial listing →
  • Active, not recruiting NCT NCT04772300

    Trial to Assess the Safety and Efficacy of Sirolimus-Coated Balloon vs. Uncoated Standard Angioplasty for the Treatment of Below-the-knee Peripheral Arterial Disease

    Not yet reported Jena University Hospital 230 participants Est. completion 2028-11-17 19 sites Stand-alone
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Completed NCT NCT04775173

    Efficacy and Safety of Different Concentrations of Sirolimus in the Treatment of Kaposiform Hemangioendothelioma.

    Not yet reported West China Hospital 79 participants Est. completion 2023-08-10 1 site Stand-alone
    Other conditions: Kaposiform Hemangioendothelioma
    View official trial listing →
  • Active, not recruiting NCT NCT04776434

    SUCCESS (SelUtion, Safety, effiCaCy, hEalth economicS and promS) PTA Study

    Not yet reported M.A. Med Alliance S.A. 723 participants Est. completion 2028-12-31 27 sites Stand-alone
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Active, not recruiting NCT NCT04789070

    Phase III Trial of Sirolimus in IBM

    Not yet reported University of Kansas Medical Center 140 participants Est. completion 2027-12 10 sites
    Other conditions: Inclusion Body Myositis
    View official trial listing →
  • Completed NCT NCT04805619

    Evaluation of the Neointimal Healing by OCT of the Tapered DES Biomime Morph (TAPER-I Study)

    Not yet reported University of Sao Paulo General Hospital 35 participants Est. completion 2021-12-08 1 site Stand-alone
    Other conditions: Atherosclerosis
    View official trial listing →
  • Completed NCT NCT04818632

    AZD9833 China PK Study

    Not yet reported AstraZeneca 28 participants Est. completion 2023-09-07 4 sites
    Other conditions: ER+, HER2-, Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT04849325

    IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease

    Not yet reported Biotyx Medical (Shenzhen) Co., Ltd. 120 participants Est. completion 2024-10 29 sites Stand-alone
    Other conditions: Critical Limb Ischemia (CLI)
    View official trial listing →
  • Status unknown NCT NCT04849533

    Belatacept With Early Steroid Withdrawal rATG and Everolimus in Renal Transplantation (BETTER Trial)

    Not yet reported University of Cincinnati 120 participants Est. completion 2024-07 2 sites
    Other conditions: Kidney Transplant Rejection
    View official trial listing →
  • Completed NCT NCT04862052

    Optimal Treatment for Coronary Drug Eluting Stent In-stent Restenosis

    Not yet reported Semmelweis University Heart and Vascular Center 108 participants Est. completion 2025-01-30 2 sites Stand-alone
    Other conditions: Coronary Stent Restenosis
    View official trial listing →
  • Status unknown NCT NCT04867720

    Efficacy and Safety of CertiroBell® Tablet Plus Tacrolimus in Primary Living Donor Liver Transplant Recipients

    Not yet reported Chong Kun Dang Pharmaceutical 112 participants Est. completion 2023-02-22 1 site
    Other conditions: Liver Transplant
    View official trial listing →
  • Terminated NCT NCT04885816

    Drug-eluting Balloon Versus Drug-eluting Stent for High Bleeding Risk Angioplasty

    Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 5 participants Est. completion 2021-09-29 1 site
    Cardiovascular disease Other conditions: High Bleeding Risk, Percutaneous Coronary Intervention (PCI)
    View official trial listing →
  • Status unknown NCT NCT04892212

    Sirolimus in Treatment of Proteinuric Flares of Lupus Nephritis

    Not yet reported, Not yet reported Peking Union Medical College Hospital 20 participants Est. completion 2023-10-30 Stand-alone
    Other conditions: Lupus Nephritis, Immunosuppression, Effect of Drug
    View official trial listing →
  • Active, not recruiting NCT NCT04893291

    Sirolimus-coated Balloon Versus Drug-eluting Stent in Native Coronary Vessels - TRANSFORM II

    Not yet reported Fondazione Ricerca e Innovazione Cardiovascolare ETS 1820 participants Est. completion 2030-08-30 53 sites Stand-alone
    Cardiovascular disease Other conditions: Coronary Artery Stenosis
    View official trial listing →
  • Completed NCT NCT04893486

    CODY: A Study Evaluating The Safety And Efficacy Of QTORIN 3.9% Sirolimus Topical Gel For The Prevention Of Basal Cell Carcinomas (BCCs) In Patients With Gorlin Syndrome

    Not yet reported Palvella Therapeutics, Inc. 73 participants Est. completion 2023-03-13 16 sites Stand-alone
    Other conditions: BCCs in Gorlin Syndrome Patients
    View official trial listing →
  • Terminated NCT NCT04895748

    DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies

    Not yet reported Novartis Pharmaceuticals 40 participants Est. completion 2026-02-13 11 sites
    Other conditions: Carcinoma, Renal Cell
    View official trial listing →
  • Status unknown NCT NCT04896177

    Sirolimus DEB in Coronary Bifurcation Lesions

    Not yet reported Shenzhen Salubris Pharmaceuticals Co., Ltd. 280 participants Est. completion 2026-09-18 1 site Stand-alone
    Other conditions: Coronary Bifurcation Lesions
    View official trial listing →
  • Active, not recruiting NCT NCT04899141

    Prospective Registry of ihtDEStiny® Coronary Stent in Regular PCI Practice

    Fundación EPIC 400 participants Est. completion 2028-05-01 20 sites
    Cardiovascular disease Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Status unknown NCT NCT04899583

    ACOART SCB BIF: Treatment of Coronary Bifurcation Lesion by Sirolimus Coated Balloon vs Paclitaxel Coated Balloon

    Not yet reported Acotec Scientific Co., Ltd 230 participants Est. completion 2025-11-01 1 site Stand-alone
    Other conditions: Coronary Bifurcation Lesions
    View official trial listing →
  • Completed NCT NCT04906304

    Comparison of Safety and Efficacy of de Novo Everolimus

    Not yet reported Shahid Beheshti University of Medical Sciences 35 participants Est. completion 2020-08-01 1 site
    Other conditions: Cytomegalovirus Infections
    View official trial listing →
  • Status unknown NCT NCT04918615

    Compare Sirolimus Coated Balloon Catheter With Paclitaxel Coated Balloon Catheter in De Novo Coronary Bifurcated Lesions

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 236 participants Est. completion 2024-12-31 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT04919226

    Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE

    Not yet reported ITM Solucin GmbH 259 participants Est. completion 2027-09 42 sites
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Status unknown NCT NCT04921722

    Percutaneous Administration of Sirolimus in the Treatment of Superficial Complicated Vascular Anomalies

    Not yet reported Children's Hospital of Fudan University 75 participants Est. completion 2025-11-01 1 site Stand-alone
    Other conditions: Kaposiform Hemangioendothelioma, Tufted Angioma, Superficial Vascular Anomalies, Superficial Lymphatic Malformations
    View official trial listing →
  • Withdrawn NCT NCT04936971

    Introduction of mTor Inhibitors and the Activation of the Cytomegalovirus (CMV) -Specific Cellular Immune Response

    Not yet reported Edoardo Melilli Est. completion 2021-09 1 site
    Other conditions: Kidney Transplantation, Cytomegalovirus Infections
    View official trial listing →
  • Active, not recruiting NCT NCT04948203

    Assessing the Efficacy of Sirolimus in Patients With COVID-19 Pneumonia for Prevention of Post-COVID Fibrosis

    Not yet reported, Not yet reported University of Chicago 60 participants Est. completion 2026-12 1 site
    Other conditions: Pulmonary Fibrosis, COVID-19 Pneumonia, Long COVID
    View official trial listing →
  • Status unknown NCT NCT04949880

    A Single-Arm Trial of Neurovascular Drug-Eluting Balloon Dilatation Catheter Treating Symptomatic Intracranial Atherosclerotic Stenosis

    Not yet reported Zhejiang Zylox Medical Device Co., Ltd. 132 participants Est. completion 2023-05 11 sites Stand-alone
    Other conditions: Intracranial Atherosclerosis
    View official trial listing →
  • Active, not recruiting NCT NCT04951050

    TARGET-PREMIER Trail in Evaluating the Safety and Efficacy of the Rapamycin Target Eluting Stent in CAS Treatment

    Not yet reported Shanghai MicroPort Medical (Group) Co., Ltd. 200 participants Est. completion 2027-12-31 1 site
    Cardiovascular disease Other conditions: Coronary Stenosis
    View official trial listing →
  • Terminated NCT NCT04965688

    Biology Guided Therapy for Breast Cancer for ER Positive

    Not yet reported Inova Health Care Services 2 participants Est. completion 2024-03-13 1 site
    Other conditions: Breast Cancer, Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT04982367

    Acoart SCB SFA: Sirolimus Coated Balloon Catheter in the Treatment of Femoropopliteal Artery Stenosis

    Not yet reported Acotec Scientific Co., Ltd 166 participants Est. completion 2024-07 1 site Stand-alone
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Status unknown NCT NCT04987463

    Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants

    Not yet reported, Not yet reported Katarzyna Kotulska 60 participants Est. completion 2026-03 2 sites
    Other conditions: Tuberous Sclerosis Complex
    View official trial listing →
  • Completed NCT NCT04989686

    Microsampling Assays for Immunosuppressive Drugs in Children

    Children's Hospital of Philadelphia 66 participants Est. completion 2025-05-01 1 site
    Other conditions: Immunosuppression
    View official trial listing →
  • Status unknown NCT NCT04993872

    Pharmacokinetics of Calcineurin & mTOR Inhibitors in HIV-1 Infected Kidney Transplant Recipients After Switch to BIC/FTC/TAF

    Not yet reported Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba 5 participants Est. completion 2024-07-01 2 sites
    Other conditions: HIV-infected Patient Kidney Transplant Recipient
    View official trial listing →
  • Withdrawn NCT NCT04994561

    VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements

    Not yet reported Vitality in Aging Research Group, Inc. Est. completion 2023-12
    Other conditions: Aging
    View official trial listing →
  • Not yet recruiting NCT NCT04995159

    Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVas™ BRS System

    Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 2150 participants Est. completion 2028-01 114 sites
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT04996719

    Effect of Rapamycin to Improve Cardiac Function in Frail Older Adults

    Not yet reported Mayo Clinic 24 participants Est. completion 2023-08-25 1 site
    Heart failure
    View official trial listing →
  • Active, not recruiting NCT NCT05012371

    Lenvatinib With Everolimus Versus Cabozantinib for Second-Line or Third-Line Treatment of Metastatic Renal Cell Cancer

    Not yet reported M.D. Anderson Cancer Center 90 participants Est. completion 2027-10-25 3 sites
    Other conditions: Advanced Clear Cell Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8
    View official trial listing →
  • Status unknown NCT NCT05032131

    Cell Therapy for IBM by Muscle Injection of ADSVF

    Not yet reported Assistance Publique - Hôpitaux de Paris 32 participants Est. completion 2024-04 1 site Stand-alone
    Other conditions: Inclusion Body Myositis
    View official trial listing →
  • Status unknown NCT NCT05033964

    The DESyne BDS Plus RCT: A Randomized Clinical Trial to Assess the Elixir DESyne BDS Plus Drug Eluting Coronary Stent System for the Treatment of de Novo Native Coronary Artery Lesions

    Not yet reported Elixir Medical Corporation 200 participants Est. completion 2026-03 14 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT05050149

    Study Evaluating the Safety and Efficacy of PTX-022 (QTORIN Sirolimus) in the Treatment of Microcystic Lymphatic Malformations

    Not yet reported Palvella Therapeutics, Inc. 12 participants Est. completion 2022-12-15 7 sites
    Other conditions: Microcystic Lymphatic Malformation
    View official trial listing →
  • Terminated NCT NCT05065411

    Efficacy & Safety Evaluation of Enobosarm in Combo With Abemaciclib in Treatment of ER+HER2- Metastatic Breast Cancer

    Not yet reported Veru Inc. 5 participants Est. completion 2024-01-09 30 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Terminated NCT NCT05066789

    CHoice of Optimal Anti-Thrombotic Strategy in Patients Undergoing Implantation of Coronary Drug-Eluting Stents 4

    Not yet reported Samsung Medical Center 100 participants Est. completion 2024-03-22 1 site
    Cardiovascular disease
    View official trial listing →
  • Withdrawn NCT NCT05079360

    Efficacy Evaluation of Sabizabulin Monotherapy Versus Active Control for Treatment of ER+HER2- Metastatic Breast Cancer

    Not yet reported Veru Inc. Est. completion 2024-05-26 26 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT05088356

    Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

    Not yet reported Stanford University 66 participants Est. completion 2028-05 1 site Stand-alone
    Other conditions: Allogeneic Hematopoietic Cell Transplantation (HCT), Advanced Hematologic Malignancies, Acute Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorders
    View official trial listing →
  • Status unknown NCT NCT05101005

    Long-term Efficacy of Drug-coated Balloon Versus Drug-eluting Stent in Large de Novo Coronary Lesions

    Not yet reported Lepu Medical Technology (Beijing) Co., Ltd. 400 participants Est. completion 2023-11
    Cardiovascular disease Other conditions: Drug-coated Balloon
    View official trial listing →
  • Completed NCT NCT05103358

    Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

    Not yet reported Aadi Bioscience, Inc. 128 participants Est. completion 2024-12-23 166 sites Stand-alone
    Other conditions: Tumor, Tumor, Solid, Metastasis, Metastatic Cancer, Cancer, Cancer Metastatic, Tumors, Neoplasms, Neoplasm Metastasis, Solid Tumor, Advanced Solid Tumor, Advanced Cancer, Malignant Solid Tumor, Malignant Solid Neoplasm, Malignant Neoplasm, Malignant Tumor, TSC, TSC1, TSC2, Metastatic Solid Tumor, Metastatic Neoplasm
    View official trial listing →
  • No Longer Available NCT NCT05108740

    MAP Treatment Plan With Afinitor for Postmenopausal Women With Advanced HR+ Breast Cancer

    Novartis Pharmaceuticals
    Other conditions: Advanced Hormone Receptor Positive (HR+) Breast Cancer
    View official trial listing →
  • Completed NCT NCT05120570

    PTCy + Sirolimus/VIC-1911 as GVHD Prophylaxis in Myeloablative PBSC Transplantation

    Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 16 participants Est. completion 2025-06-30 1 site Stand-alone
    Other conditions: Acute Leukemia, Myelodysplastic Syndromes, Myeloproliferative Neoplasm, Lymphoma
    View official trial listing →
  • Status unknown NCT NCT05124431

    Anlotinib Plus Everolimus as First-line Treatment for Advanced Non Clear Cell Renal Cell Carcinoma

    Not yet reported Fudan University 30 participants Est. completion 2024-12 1 site
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT05125523

    A Study of Sirolimus for Injection (Albumin Bound) in Patients With Advanced Solid Tumors

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 264 participants Est. completion 2024-11 1 site Stand-alone
    Other conditions: Advanced Solid Tumors
    View official trial listing →
  • Active, not recruiting NCT NCT05132166

    A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to the Best Available Treatment in Graft Versus Host Disease

    Not yet reported University Health Network, Toronto 50 participants Est. completion 2026-04-26 1 site
    Other conditions: Graft Vs Host Disease
    View official trial listing →
  • Active, not recruiting NCT NCT05132361

    SELUTION4SFA Trial

    Not yet reported M.A. Med Alliance S.A. 300 participants Est. completion 2030-12-01 38 sites Stand-alone
    Other conditions: Peripheral Arterial Disease, Superficial Femoral Artery Stenosis
    View official trial listing →
  • Available NCT NCT05134922

    Expanded Access Protocol for Subjects Previously Treated With Gedatolisib in B2151009

    Celcuity Inc 5 sites
    Other conditions: Breast Neoplasm Malignant Female
    View official trial listing →
  • Completed NCT NCT05153668

    Everolimus Trial in Laryngotracheal Stenosis

    Not yet reported Johns Hopkins University 8 participants Est. completion 2025-10-23 1 site
    Other conditions: Idiopathic Subglottic Tracheal Stenosis
    View official trial listing →
  • Withdrawn NCT NCT05170828

    Cryopreserved MMUD BM With PTCy for Hematologic Malignancies

    Not yet reported Ossium Health, Inc. Est. completion 2024-11
    Other conditions: Acute Leukemia, Myelodysplastic Syndromes, T-lymphoblastic Lymphoma, Acute Lymphocytic Leukemia, Acute Myeloid Leukemia, Acute Biphenotypic Leukemia, Acute Undifferentiated Leukemia
    View official trial listing →
  • Completed NCT NCT05180708

    A Multicenter, Phase 3 Randomized, Double-Blind, Vehicle-Controlled Study Evaluating the Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Pachyonychia Congenita

    Not yet reported Palvella Therapeutics, Inc. 87 participants Est. completion 2023-06-30 8 sites
    Other conditions: Pachyonychia Congenita
    View official trial listing →
  • Completed NCT NCT05188118

    Rapid Sequencing of Approved Therapies in Patients With Metastatic or Unresectable Clear Cell Renal Cell Carcinoma

    Not yet reported Icahn School of Medicine at Mount Sinai 10 participants Est. completion 2026-06-05 1 site
    Other conditions: Renal Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT05190627

    Effect of Loratadine in Lymphangioleiomyomatosis

    Not yet reported Institut d'Investigació Biomèdica de Bellvitge 62 participants Est. completion 2023-12-30 6 sites
    Other conditions: Lymphangioleiomyomatosis
    View official trial listing →
  • Active, not recruiting NCT NCT05193565

    Study to Compare the Efficacy and Safety After Conversion to RaparoBell® or My-Rept® in Kidney Transplant Patients

    Not yet reported Chong Kun Dang Pharmaceutical 206 participants Est. completion 2026-11 1 site Stand-alone
    Other conditions: Kidney Transplantation
    View official trial listing →
  • Completed NCT NCT05198427

    mTOR Inhibitors: the Lesions Induced by Papillomavirus for Transplant Patients.

    Hospices Civils de Lyon 45 participants Est. completion 2022-03-31 1 site
    Other conditions: Transplantation Organ
    View official trial listing →
  • Active, not recruiting NCT NCT05205499

    A Clinical Trial to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease

    Not yet reported Biotyx Medical (Shenzhen) Co., Ltd. 1059 participants Est. completion 2028-08 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT05206084

    A Clinical Investigation to Evaluate the Safety and Efficacy of IBS in Patients With Coronary Artery Disease

    Not yet reported Biotyx Medical (Shenzhen) Co., Ltd. 518 participants Est. completion 2028-01 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT05240781

    Zotarolimus vs Sirolimus Eluting Stent in High Bleeding Risk

    Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 280 participants Est. completion 2025-02-28 1 site Stand-alone
    Cardiovascular disease Other conditions: High Bleeding Risk, Percutaneous Coronary Intervention
    View official trial listing →
  • Active, not recruiting NCT NCT05252585

    A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML)

    Not yet reported Novartis Pharmaceuticals 4 participants Est. completion 2026-10-10 4 sites
    Other conditions: Renal Angiomyolipoma
    View official trial listing →
  • Status unknown NCT NCT05267548

    Investigating the Safety and Clinical Performance of Seven iVascular Devices for Endovascular Intervention in the Popliteal and/or Infrapopliteal Arteries

    iVascular S.L.U. 143 participants Est. completion 2025-05 8 sites
    Other conditions: Peripheral Arterial Disease Below The Knee
    View official trial listing →
  • Completed NCT NCT05269849

    Sirolimus for Nosebleeds in HHT

    Not yet reported Unity Health Toronto 10 participants Est. completion 2024-12-02 1 site Stand-alone
    Other conditions: Hereditary Hemorrhagic Telangiectasia, Nosebleeds, Epistaxis
    View official trial listing →
  • Completed NCT NCT05274308

    Stability of Tacrolimus, Cyclosporine A, Everolimus and Sirolimus in Whole Blood Patient Samples

    Thermo Fisher Scientific Oy 46 participants Est. completion 2022-07-26 1 site
    Other conditions: Transplantation Drugs Stability
    View official trial listing →
  • Active, not recruiting NCT NCT05293964

    Phase I Study to Evaluate SIM0270 Alone or in Combination in ER+, HER2- Locally Advanced or Metastatic Breast Cancer

    Not yet reported Jiangsu Simcere Pharmaceutical Co., Ltd. 214 participants Est. completion 2025-09-08 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT05294822

    Autologous Regenerative Islet Transplantation for Insulin-dependent Diabetes

    Not yet reported Shanghai Changzheng Hospital 20 participants Est. completion 2023-12 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT05298358

    RIC alloBMT With Post-transplant Cyclophosphamide for Refractory Systemic Sclerosis

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 1 participants Est. completion 2024-11-21 1 site Stand-alone
    Other conditions: Systemic Sclerosis
    View official trial listing →
  • Active, not recruiting NCT NCT05306340

    A Study Evaluating the Efficacy and Safety of Giredestrant Plus Everolimus Compared With the Physician's Choice of Endocrine Therapy Plus Everolimus in Participants With Estrogen Receptor-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer (evERA Breast Cancer)

    Not yet reported Genentech, Inc. 373 participants Est. completion 2026-10-15 136 sites
    Other conditions: Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT05324384

    Different Doses of Sirolimus for the Maintenance Treatment of Kaposiform Hemangioendothelioma

    Not yet reported West China Hospital 30 participants Est. completion 2025-11-30 1 site Stand-alone
    Other conditions: Hemangioendothelioma
    View official trial listing →
  • Status unknown NCT NCT05333640

    A Real-world Registry Investigating Sirolimus-coated Balloon Versus Paclitaxel-coated Balloon Angioplasty for the Treatment of Dysfunctional Arteriovenous Fistula

    Singapore General Hospital 200 participants Est. completion 2024-04-30 1 site
    Other conditions: Dialysis Access Malfunction, Stenosis
    View official trial listing →
  • Active, not recruiting NCT NCT05342519

    Daily Topical Rapamycin for Vitiligo

    Not yet reported Medical University of South Carolina 20 participants Est. completion 2027-12-01 1 site
    Other conditions: Vitiligo
    View official trial listing →
  • Active, not recruiting NCT NCT05357482

    Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

    Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 40 participants Est. completion 2027-01-31 1 site Stand-alone
    Other conditions: Sickle Cell Anemia, Beta Thalassemia
    View official trial listing →
  • Status unknown NCT NCT05362994

    Selution Sirolimus-eluting Balloon for Internal Pudendal-penile Artery Disease-related Erectile Dysfunction

    Not yet reported National Taiwan University Hospital 54 participants Est. completion 2025-02-28 1 site Stand-alone
    Other conditions: Erectile Dysfunction, Peripheral Arterial Disease, Arterial Stenosis
    View official trial listing →
  • Active, not recruiting NCT NCT05384756

    TMLI and Alemtuzumab for Treatment of Sickle Cell Disease

    Not yet reported City of Hope Medical Center 20 participants Est. completion 2026-12-01 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Active, not recruiting NCT NCT05386914

    This Study Consists of Two Study Parts Conducted Under a Single IRB. Part I: Short Term ApoE-dependent Cerebral Blood Flow Response to Sirolimus in Cognitively Normal Adults Part II: Short Term ApoE-dependent Cerebral Blood Flow and Lung Perfusion Response to Sirolimus in Cognitively Normal Adults

    Not yet reported University of Missouri-Columbia 205 participants Est. completion 2027-12 1 site Stand-alone
    Other conditions: Genetic Predisposition to Disease, Healthy Volunteers
    View official trial listing →
  • Active, not recruiting NCT NCT05406622

    MOTIV BTK Randomized Controlled Trial

    Not yet reported REVA Medical, Inc. 292 participants Est. completion 2030-03-31 26 sites Stand-alone
    Other conditions: Critical Limb Ischemia
    View official trial listing →
  • Withdrawn NCT NCT05417893

    Non-inferiority Clinical Trial to Compare the Safety and Performance of MeRes100 Sirolimus-eluting BioResorbable Vascular Scaffold System Versus Contemporary DES Platforms in Patients With de Novo Coronary Artery Lesions

    Not yet reported Meril Life Sciences Pvt. Ltd. Est. completion 2023-09-23
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT05425056

    A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery

    Not yet reported Vascular Therapies, Inc. 136 participants Est. completion 2025-08-29 22 sites Stand-alone
    Other conditions: Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD, Chronic Kidney Failure, Complication of Hemodialysis, Vascular Access Complication, Arteriovenous Fistula
    View official trial listing →
  • Status unknown NCT NCT05429684

    Precise Therapy for Refractory HER2 Positive Advanced Breast Cancer

    Not yet reported First Affiliated Hospital Xi'an Jiaotong University 120 participants Est. completion 2024-02-28 2 sites
    Other conditions: HER2+ Breast Cancer
    View official trial listing →
  • Completed NCT NCT05448625

    Genoss DES in Patients With a High Risk of Ischemic Events (GENTLE Registry)

    Yonsei University 200 participants Est. completion 2025-09-23 1 site
    Cardiovascular disease Other conditions: Drug-eluting Stent
    View official trial listing →
  • Not yet recruiting NCT NCT05458492

    Sirolimus in Cutaneous Sarcoidosis

    Not yet reported Assistance Publique - Hôpitaux de Paris 10 participants Est. completion 2027-05 Stand-alone
    Other conditions: Sarcoidosis, Cutaneous Sarcoidosis
    View official trial listing →
  • Active, not recruiting NCT NCT05467397

    Feasibility of [11C]Acetate-PET in LAM and TSC

    Not yet reported, Not yet reported Brigham and Women's Hospital 7 participants Est. completion 2026-06-30 1 site
    Other conditions: Lymphangioleiomyomatosis, Tuberous Sclerosis Complex
    View official trial listing →
  • Completed NCT NCT05471245

    AnGiographic Performance With A Sirolimus-elutiNG Balloon in the TrEatment of De Novo CoronaRy Artery Disease

    Not yet reported Fondazione Evidence per Attività e Ricerche Cardiovascolari ONLUS 110 participants Est. completion 2025-10-08 7 sites
    Other conditions: Coronary Restenosis
    View official trial listing →
  • Completed NCT NCT05490095

    Randomized Crossover of SVG101(Dispersible Tab. of Everolimus) and Afinitor 5mg in Healthy Adults

    Not yet reported Sovargen 26 participants Est. completion 2022-02-07 1 site
    Other conditions: Pharmacokinetics
    View official trial listing →
  • Completed NCT NCT05495425

    Clinical Study of NPC-12Y Gel in Patients With Skin Lesions Associated With TSC

    Not yet reported Nobelpharma 43 participants Est. completion 2024-10-30 5 sites Stand-alone
    Other conditions: Tuberous Sclerosis Complex
    View official trial listing →
  • Completed NCT NCT05501769

    ARV-471 in Combination With Everolimus for the Treatment of Advanced or Metastatic ER+, HER2- Breast Cancer

    Not yet reported Arvinas Estrogen Receptor, Inc. 32 participants Est. completion 2025-08-25 9 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT05508620

    A Study of Sirolimus for Injection (Albumin-bound) in Patients With Advanced Solid Tumors

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 270 participants Est. completion 2024-12 Stand-alone
    Other conditions: Malignant Solid Tumors
    View official trial listing →
  • Active, not recruiting NCT NCT05508906

    Phase 1b Study of OP-1250 (Palazestrant) in Combination With Ribociclib, Alpelisib, Everolimus, or Atirmociclib in ER+, HER2- Breast Cancer

    Not yet reported Olema Pharmaceuticals, Inc. 190 participants Est. completion 2028-01-31 16 sites
    Other conditions: Metastatic Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, Breast Cancer, Locally Advanced Breast Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT05522231

    Efficacy and Safety of Fruquintinib in Combination With Sintilimab in Advanced Renal Cell Carcinoma (FRUSICA-2)

    Not yet reported, Not yet reported Hutchmed 265 participants Est. completion 2025-03 48 sites
    Other conditions: Advanced Renal Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT05532072

    Rapamycin Plus Methylprednisolone Versus Methylprednisolone Alone in Active, Moderate-to-severe Graves' Orbitopathy.

    Not yet reported First Affiliated Hospital Xi'an Jiaotong University 140 participants Est. completion 2023-09 1 site
    Other conditions: Graves Ophthalmopathy
    View official trial listing →
  • Active, not recruiting NCT NCT05540223

    Safety and Clinical Performance of the Freesolve Resorbable Magnesium Scaffold System

    Not yet reported Biotronik AG 1861 participants Est. completion 2032-02 1 site Stand-alone
    Cardiovascular disease Other conditions: Atherosclerosis, Coronary, Myocardial Ischemia, Ischemic Heart Disease, Acute Coronary Syndrome, Angina Pectoris
    View official trial listing →
  • Status unknown NCT NCT05548023

    Time-trend Analysis of Clinical Characteristic and Outcomes in Patients With Unprotected Left Main Coronary Artery Disease Treated With PCI Over a 10-year Period

    Not yet reported Chinese University of Hong Kong 500 participants Est. completion 2025-02-07 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT05556681

    Study of BD Sirolimus Drug Coated Catheter for Treatment of Femoropopliteal Arteries

    Not yet reported C. R. Bard 34 participants Est. completion 2025-11-24 10 sites Stand-alone
    Other conditions: Peripheral Arterial Disease, Peripheral Artery Disease, Stenosis Artery
    View official trial listing →
  • Terminated NCT NCT05557292

    RMC-5552 Monotherapy in Adult Subjects With Recurrent Glioblastoma

    Not yet reported Nicholas Butowski 7 participants Est. completion 2025-12-31 1 site
    Other conditions: Glioblastoma, Recurrent Glioblastoma
    View official trial listing →
  • Active, not recruiting NCT NCT05563220

    Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer

    Not yet reported, Not yet reported Stemline Therapeutics, Inc. 435 participants Est. completion 2028-12-28 83 sites
    Other conditions: Breast Cancer, Metastatic Breast Cancer
    View official trial listing →
  • Terminated NCT NCT05571670

    Bile Acids in Acute Insulin Resistance

    Columbia University 3 participants Est. completion 2022-06-10 1 site
    Other conditions: PI3K Gene Mutation, AKT Gene Mutation, MTOR Gene Mutation, Cancer, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT05605665

    Low-dose Interleukin-2 and Rapamycin on sjögren's Syndrome

    Not yet reported, Not yet reported Peking University People's Hospital 30 participants Est. completion 2024-03-31 1 site
    Other conditions: Sjögren's Syndrome
    View official trial listing →
  • Active, not recruiting NCT NCT05613010

    Leveraging Technology to Improve Medication Adherence in Youth With Kidney or Liver Transplant

    Not yet reported Johns Hopkins University 65 participants Est. completion 2027-08-30 1 site Stand-alone
    Other conditions: Transplant;Failure,Kidney, Transplant; Failure, Liver, Adherence, Medication, Adherence, Patient, Adherence, Treatment
    View official trial listing →
  • Status unknown NCT NCT05613166

    Adjunctive Everolimus Treatment of Refractory Epilepsy

    Not yet reported National Institute on Drug Dependence, China 108 participants Est. completion 2023-03 1 site
    Other conditions: Epilepsy
    View official trial listing →
  • Status unknown NCT NCT05616156

    The Cre8™ BTK Post Market Clinical Follow-up Study

    CID S.p.A. 50 participants Est. completion 2023-07 2 sites
    Other conditions: Peripheral Arterial Disease
    View official trial listing →
  • Status unknown NCT NCT05625919

    A Study of Safety and Efficacy of Sirolimus for Injection (Albumin-bound) in Patients With Advanced Malignant Perivascular Epithelioid Cell Tumor (PEComa)

    Not yet reported, Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 54 participants Est. completion 2024-11 1 site Stand-alone
    Other conditions: Advanced Malignant Perivascular Epithelioid Cell Tumor (PEComa)
    View official trial listing →
  • Status unknown NCT NCT05662618

    To Verify the Efficacy and Safety of Rapamycin Coated Peripheral Balloon Catheter in the Treatment of Femoral Popliteal Artery Disease

    Not yet reported Shanghai Bomaian Medical Technology Co., Ltd 276 participants Est. completion 2025-06-30 1 site
    Other conditions: Peripheral Arterial Disease
    View official trial listing →
  • Completed NCT NCT05663944

    REpurposing SirolimUS in Compensated Advanced Chronic Liver Disease. the RESUS Proof of Concept Study

    Not yet reported Nottingham University Hospitals NHS Trust 41 participants Est. completion 2024-06-25 1 site Stand-alone
    Other conditions: Advanced Chronic Liver Disease
    View official trial listing →
  • Terminated NCT NCT05667285

    BIOFLOW-china Post-marketing Study (BIOTRONIK)

    Biotronik (Beijing) Medical Device Ltd. 122 participants Est. completion 2024-09-27 2 sites
    Other conditions: In-Stent Stenosis (Restenosis) of Coronary Artery Stent, Native Coronary Artery Stenosis
    View official trial listing →
  • Completed NCT NCT05677711

    Safety and Efficacy of the Ultimaster Stent

    Yonsei University 204 participants Est. completion 2025-01-03 1 site
    Cardiovascular disease Other conditions: Drug-eluting Stents
    View official trial listing →
  • Status unknown NCT NCT05703646

    Safety and Clinical Performance of the Yukon Choice PC, Yukon Chrome PC & Yukon Choice Flex Stents in Routine Practice

    Translumina GmbH 5000 participants Est. completion 2026-03-30 1 site
    Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Active, not recruiting NCT NCT05705973

    Ultimaster Nagomi™ Sirolimus Eluting Coronary Stent System in Complex PCI Patients

    Terumo Europe N.V. 3000 participants Est. completion 2027-04-29 52 sites
    Cardiovascular disease Other conditions: Coronary Artery Occlusion, Ischemic Heart Disease
    View official trial listing →
  • Completed NCT NCT05719883

    Evaluating the Safety and Efficacy of the Maurora® DES in ICAS

    Not yet reported Beijing Tiantan Hospital 156 participants Est. completion 2025-05-15 1 site Stand-alone
    Cardiovascular disease Other conditions: Intracranial Arteriosclerosis
    View official trial listing →
  • Not yet recruiting NCT NCT05746689

    Study of Sirolimus in IgG4-related Disease

    Not yet reported Peking University International Hospital 20 participants Est. completion 2028-12-31 Stand-alone
    Other conditions: IgG4-related Disease
    View official trial listing →
  • Terminated NCT NCT05773326

    Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

    Not yet reported Nader Sanai 5 participants Est. completion 2025-10-16 1 site
    Other conditions: High Grade Glioma, Glioma, Glioma, Malignant, Glioblastoma
    View official trial listing →
  • Status unknown NCT NCT05780359

    Evaluating the Safety and Efficacy of the G-stream® Drug-Eluting Stent in the Above-the-Knee Femoropopliteal Artery

    Not yet reported Shenzhen Salubris Pharmaceuticals Co., Ltd. 280 participants Est. completion 2026-08-31 1 site Stand-alone
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Status unknown NCT NCT05801003

    Cutting Balloon Predilation Prior to Abluminus Sirolimus-eluting Stent Implantation (CUT-DRESS).

    Not yet reported Hospital Universitario La Fe 96 participants Est. completion 2025-01-01 3 sites
    Cardiovascular disease Other conditions: Percutaneous Coronary Intervention, Cutting Balloon
    View official trial listing →
  • Active, not recruiting NCT NCT05810870

    PIK3CA/PTEN-altered Advanced Breast Cancer Treated With MEN1611 Monotherapy or in Combination With Eribulin

    Not yet reported MedSIR 14 participants Est. completion 2027-07 13 sites
    Other conditions: Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT05826964

    Levels of Circulating Tumor DNA as a Predictive Marker for Early Switch in Treatment for Patients With Metastatic (Stage IV) Breast Cancer

    Not yet reported University of Miami 24 participants Est. completion 2029-07-31 1 site
    Other conditions: Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT05833815

    Addition of Everolimus to Standard of Care in Carcinoma Gallbladder

    Not yet reported, Not yet reported Banaras Hindu University 56 participants Est. completion 2024-12-30 1 site
    Other conditions: Gallbladder Cancer
    View official trial listing →
  • Completed NCT NCT05835999

    Everolimus Aging Study

    Not yet reported University of Wisconsin, Madison 106 participants Est. completion 2026-07-22 1 site
    Other conditions: Aging, Insulin Resistance
    View official trial listing →
  • Active, not recruiting NCT NCT05836025

    Effect of Rapamycin in Ovarian Aging

    Not yet reported Columbia University 50 participants Est. completion 2026-09 1 site
    Other conditions: Perimenopausal
    View official trial listing →
  • Terminated NCT NCT05840510

    Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19)

    Not yet reported Mirati Therapeutics Inc. 6 participants Est. completion 2024-12-27 3 sites Stand-alone
    Other conditions: Solid Tumor, Adult, NSCLC, Advanced Cancer, Metastatic Cancer, Malignant Neoplastic Disease
    View official trial listing →
  • Active, not recruiting NCT NCT05860881

    Topical Sirolimus in Chemoprevention of Facial Squamous Cell Carcinomas in Solid Organ Transplant Recipients (SiroSkin)

    Not yet reported Melanoma and Skin Cancer Trials Limited 146 participants Est. completion 2027-09-30 6 sites Stand-alone
    Other conditions: Solid Organ Transplant Recipients, Skin Cancer
    View official trial listing →
  • Completed NCT NCT05915468

    Large De-NOVo Coronary artEry Disease Treated With Sirolimus Drug Eluting Balloon (LOVE DEB)

    Wrightington, Wigan and Leigh NHS Foundation Trust 306 participants Est. completion 2025-12-11 1 site
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT05920512

    Combination Regimen With Sodium Valproate for Severe Hemophilia: a Single-arm, Phase 1, Pilot Trial.

    Not yet reported, Not yet reported Xue-chun Lu 10 participants Est. completion 2025-04-01 1 site Stand-alone
    Other conditions: Hemophilia
    View official trial listing →
  • Status unknown NCT NCT05938530

    Sirolimus Drug-coated Balloon Versus Stent Graft

    Not yet reported Singapore General Hospital 100 participants Est. completion 2026-08 1 site Stand-alone
    Other conditions: Arteriovenous Shunt Thrombosis, Blood Vessel Prosthesis
    View official trial listing →
  • Active, not recruiting NCT NCT05946629

    SELUTION 4 De Novo Small Vessel IDE Trial

    Not yet reported M.A. Med Alliance S.A. 960 participants Est. completion 2031-09 70 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT05952206

    Ischemic and Bleeding Outcomes After Angiolite Stent Implantation and an Abbreviated Dual Antiplatelet Therapy

    Not yet reported iVascular S.L.U. 2312 participants Est. completion 2030-01-13 38 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT05954442

    Everolimus With Investigator's Choice of Chemotherapy in Advanced Triple-Negative Breast Cancer (TNBC) With Luminal Androgen Receptor (LAR) Subtype

    Not yet reported Fudan University 203 participants Est. completion 2026-08 1 site
    Other conditions: Triple Negative Breast Cancer, Metastatic Breast Cancer, Mutation
    View official trial listing →
  • Status unknown NCT NCT05963620

    Long-term Follow-up of a Randomized Comparison of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Surgery

    Heart Center Leipzig - University Hospital 201 participants Est. completion 2024-02 4 sites
    Cardiovascular disease Other conditions: Coronary Stenosis
    View official trial listing →
  • Status unknown NCT NCT05971394

    IBS Titan™ Sirolimus-eluting Iron Bioresorbable Peripheral Scaffold System Clinical Trial

    Not yet reported Biotyx Medical (Shenzhen) Co., Ltd. 100 participants Est. completion 2026-07 1 site Stand-alone
    Other conditions: Infrapopliteal Lesions, Critical Limb Ischemia
    View official trial listing →
  • Completed NCT NCT05997056

    Trial of Nab-sirolimus in Patients With Well-differentiated Neuroendocrine Tumors (NETs) of the Gastrointestinal Tract, Lung, or Pancreas Who Have Not Received Prior Treatment With mTOR Inhibitors

    Not yet reported Aadi Bioscience, Inc. 12 participants Est. completion 2025-10-03 4 sites Stand-alone
    Other conditions: Neuroendocrine Tumors, NET, Pancreatic Neuroendocrine Tumor, Gastrointestinal Neuroendocrine Tumor, Pulmonary Neuroendocrine Tumor
    View official trial listing →
  • Completed NCT NCT06013007

    Joint Inflation With Nominal-pressure and Stability Approach in DES Optimization

    Not yet reported Zunyi Medical College 161 participants Est. completion 2026-03-05 1 site Stand-alone
    Other conditions: Acute Coronary Syndrome, De Novo Stenosis
    View official trial listing →
  • Completed NCT NCT06022068

    Evaluating Rapamycin Treatment in Alzheimer's Disease Using Positron Emission Tomography

    Not yet reported, Not yet reported Karolinska Institutet 14 participants Est. completion 2025-01-17 1 site Stand-alone
    Other conditions: Alzheimer Disease
    View official trial listing →
  • Withdrawn NCT NCT06056193

    The SIR-POBA Bypass Trial

    Not yet reported Paracelsus Medical University Est. completion 2027-10-01 1 site
    Alcohol use disorder Other conditions: Peripheral Arterial Occlusive Disease, Bypass Complication, Femoropopliteal Artery Occlusion, Femoropopliteal Stenosis, Critical Limb-Threatening Ischemia
    View official trial listing →
  • Withdrawn NCT NCT06056206

    The SIR-POBA Shunt Trial

    Not yet reported Paracelsus Medical University Est. completion 2027-10-01 1 site
    Other conditions: Arteriovenous Fistula Stenosis
    View official trial listing →
  • Completed NCT NCT06065345

    BRight Pharmacokinetic Study

    Not yet reported Biotronik CRC Inc. 6 participants Est. completion 2025-07-22 1 site
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Completed NCT NCT06066476

    Efficacy and Safety of GENOSS® DES in Patients with Coronary Artery Disease

    Genoss Co., Ltd. 1022 participants Est. completion 2024-10-31 1 site
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT06075368

    Efficacy and Safety of GENOSS® SES in Patients With Acute Coronary Syndrome (GENOSS ACS)

    Genoss Co., Ltd. 757 participants Est. completion 2027-12-31 1 site
    Other conditions: Acute Coronary Syndrome, Percutaneous Coronary Intervention
    View official trial listing →
  • Terminated NCT NCT06078696

    Siplizumab for Sickle Cell Disease Transplant

    Not yet reported, Not yet reported Columbia University 1 participants Est. completion 2025-12-11 1 site Stand-alone
    Other conditions: Anemia, Sickle Cell
    View official trial listing →
  • Withdrawn NCT NCT06080165

    Sirolimus for Improving Social Abilities in People With PTEN Germline Mutations

    Not yet reported, Not yet reported Stanford University Est. completion 2028-06 3 sites Stand-alone
    Other conditions: PTEN Gene Mutation, PTEN Hamartoma Tumor Syndrome, PTEN Hamartoma Syndrome
    View official trial listing →
  • Enrolling by invitation NCT NCT06086496

    Effectiveness and Safety of Abluminal Biodegradable Polymer Sirolimus-eluting Stent (GENOSS® DES)

    Genoss Co., Ltd. 1000 participants Est. completion 2027-12-31 1 site
    Cardiovascular disease Other conditions: Percutaneous Coronary Intervention
    View official trial listing →
  • Active, not recruiting NCT NCT06105632

    A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment

    Not yet reported Pfizer 333 participants Est. completion 2028-01-21 48 sites
    Other conditions: Advanced or Metastatic Breast Cancer
    View official trial listing →
  • Not yet recruiting NCT NCT06122974

    Drug Eluting Temporary Spur Stent System vs Percutaneous Balloon Angioplasty for the Treatment of Critical Limb Ischemia

    Not yet reported ReFlow Medical, Inc. 518 participants Est. completion 2037-12
    Other conditions: Critical Limb Ischemia
    View official trial listing →
  • Active, not recruiting NCT NCT06145282

    Non-myeloablative Haploidentical HCT Study for Patients With Sickle Cell Disease, Including Compromised Organ Function

    Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 6 participants Est. completion 2027-11-26 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Status unknown NCT NCT06160739

    Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular Malformations

    Sohag University 10 participants Est. completion 2024-09-01 1 site
    Other conditions: Microcystic Lymphatic Malformation, Combined Vascular Malformation, Vascular Malformations
    View official trial listing →
  • Enrolling by invitation NCT NCT06168305

    Safety and Effectiveness of GENOSS® DES in Patients With Multivessel Coronary Artery Disease

    Genoss Co., Ltd. 1000 participants Est. completion 2028-02-28 1 site
    Cardiovascular disease Other conditions: Percutaneous Coronary Intervention
    View official trial listing →
  • Status unknown NCT NCT06197022

    Scoring-Balloon Angioplasty and Sirolimus-Eluting Balloon Angioplasty for the Treatment of Diffuse, Small Vessel Coronary Artery Disease (SCA-DEB Study)

    Not yet reported University National Heart Hospital 106 participants Est. completion 2024-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Active, not recruiting NCT NCT06214819

    Plan to Evaluate Early Endothelialization of a Polymer Free Sirolimus-eluting Coronary Stent System (VIVO ISARTM) Compared With Everolimus-eluting Durable Polymer Stent (XIENCE SkypointTM) in Patients Undergoing Percutaneous Coronary Intervention.

    Not yet reported Fundación EPIC 40 participants Est. completion 2026-08-31 4 sites
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT06225206

    Analysis of Donor-derived Cell Free DNA in Liver Transplant Patients

    Methodist Health System 300 participants Est. completion 2024-12-31 1 site
    Other conditions: Liver Transplant Failure
    View official trial listing →
  • Completed NCT NCT06235905

    Open-Label of SPN-820 in Adults With Major Depressive Disorder

    Not yet reported Navitor Pharmaceuticals, Inc. 40 participants Est. completion 2024-08-18 1 site
    Other conditions: Major Depressive Disorder
    View official trial listing →
  • Active, not recruiting NCT NCT06239480

    SELVA: A Phase 3 Study Evaluating QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations

    Not yet reported Palvella Therapeutics, Inc. 51 participants Est. completion 2026-07 15 sites
    Other conditions: Microcystic Lymphatic Malformation
    View official trial listing →
  • Enrolling by invitation NCT NCT06257420

    Low Dose Rapamycin in ME/CFS, Long-COVID, and Other Infection Associated Chronic Conditions

    Simmaron Research Inc. 150 participants Est. completion 2027-07-01 5 sites
    Other conditions: Myalgic Encephalomyelitis, Long-COVID
    View official trial listing →
  • Status unknown NCT NCT06279494

    Sirolimus+Abatacept+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to Calcineurin Inhibitors

    Not yet reported, Not yet reported Peking University People's Hospital 6 participants Est. completion 2025-03 Stand-alone
    Other conditions: Acute Leukemia, Myelodysplastic Syndromes, Severe Aplastic Anemia
    View official trial listing →
  • Not yet recruiting NCT NCT06300268

    Advapro Coronary Stent System in Coronary Artery Diseased Patients.

    Not yet reported Advanced MedTech Solutions Pvt. Ltd. 120 participants Est. completion 2026-12
    Cardiovascular disease Other conditions: De Novo Stenosis Lesion, Coronary Stent Implantation
    View official trial listing →
  • Not yet recruiting NCT NCT06301386

    Everolimus Combined With PD-1 in Advanced Colorectal Cancer Patients

    Not yet reported Fudan University 25 participants Est. completion 2026-12-01 2 sites
    Other conditions: Colon Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT06308419

    A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions

    Not yet reported M.D. Anderson Cancer Center 18 participants Est. completion 2031-02-01 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Soft-tissue Sarcomas
    View official trial listing →
  • Not yet recruiting NCT NCT06308445

    Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis

    Not yet reported University Hospital, Toulouse 25 participants Est. completion 2030-09 4 sites
    Other conditions: Familial Adenomatous Polyposis
    View official trial listing →
  • Status unknown NCT NCT06317298

    Fruquintinib Plus Everolimus as 2nd Line Therapy of ccRCC Patients Progressed Post IO and TKI Therapy

    Not yet reported Peking University First Hospital 36 participants Est. completion 2025-12-01 1 site
    Other conditions: Renal Cell Carcinoma, Clear Cell, Somatic
    View official trial listing →
  • Status unknown NCT NCT06338306

    Tacrolimus and Personalized Therapy to Prevent Acute Rejection Episodes

    Fondazione IRCCS Policlinico San Matteo di Pavia 25 participants Est. completion 2025-06-30 1 site
    Other conditions: Heart Transplant Failure
    View official trial listing →
  • Status unknown NCT NCT06340373

    Clinical and Angiographic Outcomes of Post-drug-coated Balloon Angioplasty in Native Coronary Lesions

    National Institute of Cardiovascular Diseases, Bangladesh 303 participants Est. completion 2025-06-30 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT06341998

    Clinical Study of Chemotherapy in the Treatment of Recurrent/Refractory Yolk Sac Tumor in Children

    Not yet reported, Not yet reported Shandong First Medical University 32 participants Est. completion 2024-02-01 1 site Stand-alone
    Other conditions: Germ Cell Tumor, Yolk Sac Tumor
    View official trial listing →
  • Status unknown NCT NCT06345209

    Efficacy and Safety of Sirolimus-coated Coronary Balloon Dilatation Catheter for Coronary Small Vessels

    Not yet reported BrosMed Medical Co., Ltd 236 participants Est. completion 2025-12 Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT06409507

    Research and Application for New Clinical Diagnosis and Treatment System for HBV Related HCC Liver Transplantation

    First People's Hospital of Hangzhou 178 participants Est. completion 2023-08-01
    Other conditions: Hepatocellular Carcinoma, Liver Transplantation, Prognosis
    View official trial listing →
  • Active, not recruiting NCT NCT06428396

    Study of Belzutifan (MK-6482) Plus Fulvestrant for ER+/HER2- Metastatic Breast Cancer (MK-6482-029/LITESPARK-029)

    Not yet reported Merck Sharp & Dohme LLC 120 participants Est. completion 2028-12-25 41 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT06494150

    Nab-Sirolimus and Endocrine Therapy in Recurrent Low Grade Serous Ovarian Cancer (NARETO)

    Not yet reported University of Oklahoma 37 participants Est. completion 2029-09 1 site Stand-alone
    Other conditions: Low Grade Ovarian Serous Adenocarcinoma
    View official trial listing →
  • Status unknown NCT NCT06504225

    EVEROLD LONG TERM FOLLOW-UP

    University Hospital, Brest 260 participants Est. completion 2025-08-01 14 sites
    Other conditions: Transplant; Complication, Failure
    View official trial listing →
  • Completed NCT NCT06550271

    The Bioavailability of Compounded and Generic Rapamycin in Normative Aging Individuals

    AgelessRx 67 participants Est. completion 2023-12-15 1 site
    Other conditions: Aging
    View official trial listing →
  • Status unknown NCT NCT06561022

    Precision Treatment of HR+ HER2- Advanced Breast Cancer Based on SNF Molecular Subtyping

    Not yet reported Fudan University 260 participants Est. completion 2026-06-30 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT06563817

    The Safety and Efficacy of Rapamycin on Communicating Hydrocephalus Secondary to Intraventricular Hemorrhage

    Not yet reported Beijing Tiantan Hospital 53 participants Est. completion 2025-07 1 site Stand-alone
    Other conditions: Communicating Hydrocephalus, Cerebral Intraventricular Hemorrhage, Secondary Normal Pressure Hydrocephalus, Post Hemorrhagic Hydrocephalus
    View official trial listing →
  • Status unknown NCT NCT06584773

    Efficacy of a Quadruple Immunosuppressor Regimen With mTOR Inhibitors in Sensitized Kidney Transplant Patients

    Not yet reported University of Sao Paulo General Hospital 80 participants Est. completion 2025-07 1 site
    Other conditions: Disorder Related to Renal Transplantation
    View official trial listing →
  • Not yet recruiting NCT NCT06607198

    Clinical-pathological Evaluation of Pit-NETs

    Fondazione Policlinico Universitario Agostino Gemelli IRCCS 940 participants Est. completion 2026-10-01 1 site
    Other conditions: Pituitary, Cancer, Neuroendocrine Tumors
    View official trial listing →
  • Not yet recruiting NCT NCT06614972

    Balloon-expandable DES for ICAS Registry Study (BDES-ICAS Registry)

    RenJi Hospital 520 participants Est. completion 2030-09-30
    Cardiovascular disease Other conditions: Atheroscleroses, Cerebral, Intracranial Atherosclerosis
    View official trial listing →
  • Active, not recruiting NCT NCT06621524

    EucaLimus Post-Market Registry

    OrbusNeich 251 participants Est. completion 2029-01 10 sites
    Other conditions: Coronary Arterioscleroses
    View official trial listing →
  • Active, not recruiting NCT NCT06653842

    A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Cutaneous Venous Malformations

    Not yet reported Palvella Therapeutics, Inc. 15 participants Est. completion 2026-03 10 sites
    Other conditions: Cutaneous Venous Malformations
    View official trial listing →
  • Active, not recruiting NCT NCT06680921

    A Study of SIM0270 Combined With Everolimus vs. Treatment of Physician's Choice in Patients With ER+/HER2- Advanced Breast Cancer (SIMRISE)

    Not yet reported Jiangsu Simcere Pharmaceutical Co., Ltd. 482 participants Est. completion 2028-08-31 57 sites
    Other conditions: Locally Advanced or Metastatic Breast Cancer
    View official trial listing →
  • Not yet recruiting NCT NCT06682611

    Safety and Efficacy of SYHA1813 Single Agent or in Combination With Different Regimens in Unresectable Locally Advanced or Metastatic Solid Tumors.

    Not yet reported, Not yet reported Shanghai Runshi Pharmaceutical Technology Co., Ltd 380 participants Est. completion 2027-11-13
    Other conditions: Unresectable Locally Advanced or Metastatic Solid Tumors
    View official trial listing →
  • Not yet recruiting NCT NCT06682767

    A Nutritional and Pharmacological Intervention for Body, Brain, and Longevity Effects (NIBBLE)

    Not yet reported, Not yet reported Cedars-Sinai Medical Center 60 participants Est. completion 2028-06 1 site
    Other conditions: Cerebral Blood Flow, APOE 4
    View official trial listing →
  • Status unknown NCT NCT06683118

    Registration Trial of the Drug-coated Balloon for the Symptomatic Cerebral Atherosclerotic Stenosis

    Not yet reported MicroPort NeuroTech Co., Ltd. 212 participants Est. completion 2026-07-27 2 sites
    Other conditions: Cerebral Atherosclerotic Stenosis
    View official trial listing →
  • Not yet recruiting NCT NCT06708455

    Phase 2b of RAPA-201 Cell Therapy in Post-PD-(L)-1 Melanoma

    Not yet reported Rapa Therapeutics LLC 65 participants Est. completion 2029-09-30 1 site
    Other conditions: Malignant Melanoma With Metastasis, Malignant Melanoma, Malignant Melanoma Stage IIIc, Malignant Melanoma Stage IV
    View official trial listing →
  • Active, not recruiting NCT NCT06752694

    Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia

    Not yet reported Fred Hutchinson Cancer Center 1 participants Est. completion 2026-10-15 1 site Stand-alone
    Other conditions: Aplastic Anemia
    View official trial listing →
  • Active, not recruiting NCT NCT06789900

    Everolimus and/or Exercise to Prevent Bone Loss in Postmenopausal Women

    Not yet reported Odense University Hospital 136 participants Est. completion 2026-10-01 1 site
    Other conditions: Postmenopausal Women
    View official trial listing →
  • Active, not recruiting NCT NCT06821542

    A Study to Evaluate Axatilimab Versus Best Available Therapy in Participants With Chronic Graft Versus Host Disease After at Least 2 Prior Lines of Systemic Therapy

    Not yet reported Incyte Corporation 9 participants Est. completion 2032-11-30 130 sites
    Other conditions: Chronic Graft-versus-host-disease
    View official trial listing →
  • Active, not recruiting NCT NCT06841510

    Efficacy and Safety of GENOSS SES in Patients With Coronary Artery Disease

    Genoss Co., Ltd. 1118 participants Est. completion 2025-11-30 1 site
    Other conditions: Coronary Arterial Disease (CAD)
    View official trial listing →
  • Enrolling by invitation NCT NCT06843811

    Sirolimus for Leigh Syndrome

    Not yet reported Matthew Demczko 15 participants Est. completion 2027-12 1 site Stand-alone
    Other conditions: Leigh Syndrome
    View official trial listing →
  • Withdrawn NCT NCT06857045

    Comparison Three vs Six Months of Dual Anti-platelet Therapy After Sirolimus-eluting Stent Implantation

    Not yet reported Sino Medical Sciences Technology Inc. Est. completion 2026-06 1 site Stand-alone
    Other conditions: Intracranial Arteriosclerosis, Intracranial Artery Stenosis, Drug-Eluting Stents
    View official trial listing →
  • Suspended NCT NCT06876142

    Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple Myeloma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 54 participants Est. completion 2033-01-01 1 site Stand-alone
    Other conditions: Multiple Myeloma, Relapsed and/or Refractory Multiple Myeloma (RRMM)
    View official trial listing →
  • Completed NCT NCT06914089

    Thin Versus Thicker Strut Thickness Stents in Primary Percutaneous Intervention

    Not yet reported Assiut University 146 participants Est. completion 2023-09-30 1 site
    Other conditions: Primary Percutaneous Coronary Intervention
    View official trial listing →
  • Not yet recruiting NCT NCT06925971

    A Randomized Trial of the Rapamycin Target Eluting Stent for the Treatment of Symptomatic Cerebral Artery Atherosclerotic Disease(TARGET-DREAM)

    Not yet reported MicroPort NeuroTech Co., Ltd. 279 participants Est. completion 2027-10-01 1 site
    Other conditions: Intracranial Arteriosclerosis
    View official trial listing →
  • Not yet recruiting NCT NCT06928883

    Ticin Pilot Study: Sirolimus-Eluting Balloon for Stabilization and Regression of Non-Obstructive Coronary Plaques.

    Not yet reported Cardiocentro Ticino 24 participants Est. completion 2028-12-31 1 site Stand-alone
    Cardiovascular disease Other conditions: Coronary Arterial Disease (CAD), Vulnerable Coronary Plaques, Coronary Vessel, Acute Coronary Syndromes (ACS)
    View official trial listing →
  • Not yet recruiting NCT NCT06929325

    Sirolimus for Injection (Albumin-bound) Combined With Fulvestrant for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Previously Treated With CDK4/6 Inhibitors

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 312 participants Est. completion 2027-12 1 site Stand-alone
    Other conditions: HR+/HER2- Advanced/Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT06940895

    Evaluating the Safety and Efficacy of Topical Sirolimus 0.2% to Treat Acanthosis Nigricans

    Not yet reported Narrows Institute for Biomedical Research 5 participants Est. completion 2025-07-18 1 site Stand-alone
    Other conditions: Acanthosis Nigricans
    View official trial listing →
  • Not yet recruiting NCT NCT06941142

    A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast Cancer

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 382 participants Est. completion 2028-06 Stand-alone
    Other conditions: Advanced Breast Cancer
    View official trial listing →
  • Not yet recruiting NCT NCT06942156

    Optimize Immunosuppressive Therapy Using Everolimus and Low-dose Calcineurin Inhibitors in Heart Transplant Patients in Korea

    Not yet reported Chong Kun Dang Pharmaceutical 140 participants Est. completion 2030-12 1 site
    Other conditions: Heart Transplant
    View official trial listing →
  • Active, not recruiting NCT NCT06957379

    Sirolimus for Injection (Albumin-bound) in Combination With Endocrine Therapy for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Who Have Failed Standard Therapy

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 78 participants Est. completion 2025-12 1 site Stand-alone
    Other conditions: HR+/HER2- Advanced/Metastatic Breast Cancer
    View official trial listing →
  • Not yet recruiting NCT NCT06981845

    Sirolimus With corTicOsteroid TheraPy for Rapid rEcurrences of Coronary Unexplained In-stent Restenosis

    Not yet reported China National Center for Cardiovascular Diseases 52 participants Est. completion 2028-06-01 Stand-alone
    Cardiovascular disease Other conditions: In-stent Restenosis Lesion
    View official trial listing →
  • Not yet recruiting NCT NCT06994572

    Study of CT-01 as Monotherapy and Combination Therapy in Subjects With Intermediate or Advanced Hepatocellular Carcinoma

    Not yet reported Captor Therapeutics S.A. 141 participants Est. completion 2030-04-01
    Other conditions: Hepatocellular Carcinoma (HCC)
    View official trial listing →
  • Active, not recruiting NCT NCT07054320

    Rapamycin and Infection-related Illness

    Hoskinson Health and Wellness Clinic 15 participants Est. completion 2026-06 1 site
    Other conditions: Infectious Diseases
    View official trial listing →
  • Active, not recruiting NCT NCT07058974

    A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation

    Not yet reported Icahn School of Medicine at Mount Sinai 20 participants Est. completion 2027-06-15 1 site Stand-alone
    Other conditions: Smokers, Former Smokers
    View official trial listing →
  • Not yet recruiting NCT NCT07081763

    Immunotherapy With Baricitinib and Sirolimus, Alone and in Combination, for the Control of HIV-1 Replication After Antiretroviral Treatment Interruption

    Not yet reported ANRS, Emerging Infectious Diseases 191 participants Est. completion 2030-11 Stand-alone
    Other conditions: HIV-1-infection
    View official trial listing →
  • Enrolling by invitation NCT NCT07113743

    Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 10 participants Est. completion 2029-09-01 1 site Stand-alone
    Other conditions: Chronic Granulomatous Disease (CGD)
    View official trial listing →
  • Active, not recruiting NCT NCT07151157

    Therapeutic Value of Sirolimus in Refractory Adult-Onset Still's Disease

    Not yet reported Ruijin Hospital 3 participants Est. completion 2026-08-30 1 site Stand-alone
    Other conditions: Adult-Onset Still's Disease
    View official trial listing →
  • Enrolling by invitation NCT NCT07159087

    The Safety and Efficacy for In-segment Late Lumen Loss of the 'Genoss® SCB' Versus 'SeQuent® Please NEO' in Patients With Coronary ISR

    Not yet reported Genoss Co., Ltd. 94 participants Est. completion 2027-01-31 1 site Stand-alone
    Other conditions: Coronary Arterial Disease (CAD)
    View official trial listing →
  • Not yet recruiting NCT NCT07166354

    Clinical Study of mTOR Inhibitor as a Treatment for Grey Hair (Canities)

    Not yet reported, Not yet reported Applied Biology, Inc. 100 participants Est. completion 2027-09-15
    Other conditions: Canities, Grey Hair
    View official trial listing →
  • Not yet recruiting NCT NCT07173556

    A Phase Ib/II Study of QLC1401 Combined With CDK4/6 or mTOR Inhibitors in ER+/HER2- Advanced Breast Cancer

    Not yet reported, Not yet reported Qilu Pharmaceutical Co., Ltd. 96 participants Est. completion 2028-10
    Other conditions: Advanced Breast Cancer
    View official trial listing →
  • Not yet recruiting NCT NCT07203664

    Use of Tacrolimus and MTOR Inhibitors With Anticipatory Therapy vs. Tacrolimus and Mycophenolic Acid With Universal Prophylaxis in Renal Recipients at High Risk of Posttransplant Cytomegalovirus.

    Not yet reported Hospital Universitario La Paz 30 participants Est. completion 2026-12-31 1 site
    Other conditions: Evaluate the Effectiveness of CMV Prevention Strategies in Kidney Transplant Recipients
    View official trial listing →
  • Not yet recruiting NCT NCT07218575

    Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations

    Not yet reported, Not yet reported Boston Children's Hospital 60 participants Est. completion 2030-09 3 sites
    Other conditions: Cowden's Disease, Cowden's Syndrome, Lhermitte-Duclos Disease, Cerebellum Dysplastic Gangliocytoma, Bannayan Zonana Syndrome, Myhre Riley Smith Syndrome, Riley Smith Syndrome, PTEN Hamartoma Tumor Syndrome, Bannayan Riley Ruvalcaba Syndrome
    View official trial listing →
  • Completed NCT NCT07302932

    Metformin and Molecular Aging in Prediabetes

    Not yet reported Diabetes Foundation, India 112 participants Est. completion 2025-01-30 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT07326735

    MIRAGE Study: Clinical Outcomes of the Mamba Sirolimus-Eluting PTCA Balloon

    Not yet reported Frisch Medical Device Private Limited 360 participants Est. completion 2024-03-03 2 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Withdrawn NCT NCT07329088

    Isoleucine Addition Treatment Effects in a Controlled Diet Study

    Not yet reported Jean L. Fry Est. completion 2029-01-31 1 site
    PrediabetesMetabolic syndrome Other conditions: Obesity & Overweight
    View official trial listing →
  • Not yet recruiting NCT NCT07350057

    A Preliminary Clinical Study on the Efficacy of Cyclophosphamide and Sirolimus Combined With VIC-1911 in Preventing Graft-versus-Host Disease After Haploidentical Stem Cell Transplantation in Children

    Not yet reported Shanghai Jiao Tong University School of Medicine 9 participants Est. completion 2027-12-01 Stand-alone
    Other conditions: GVHD (Acute or Chronic)
    View official trial listing →
  • Active, not recruiting NCT NCT07354620

    A Pilot Study on Reverse Aging (The REVERSE Study)

    Not yet reported The Christ Hospital 52 participants Est. completion 2026-05 1 site
    Other conditions: Aging
    View official trial listing →
  • Not yet recruiting NCT NCT07359807

    A Study Comparing the MAGICTouch™ Sirolimus-coated Balloon With a Paclitaxel-coated Balloon for Treating Severe Narrowing or Blockage in the Femoropopliteal Arteries.

    Not yet reported, Not yet reported Concept Medical Inc. 478 participants Est. completion 2033-01 Stand-alone
    Other conditions: Popliteal Artery Disease, Superficial Femoral Artery Disease
    View official trial listing →
  • Not yet recruiting NCT NCT07407517

    Adjuvant Intensification for LAR

    Not yet reported Fudan University 904 participants Est. completion 2033-02-01
    Other conditions: Breast Cancer Females, Triple Negative Breast Cancer (TNBC)
    View official trial listing →
  • Not yet recruiting NCT NCT07408674

    COMPETE-LM Trial: Drug-Coated Balloon-Enhanced Provisional Stenting in Complex Left Main Disease.

    Not yet reported Rede Optimus Hospitalar SA 186 participants Est. completion 2029-05
    Other conditions: Complex Left Main Bifurcation Stenosis, Left Main Coronary Artery Stenosis, Coronary Bifurcation Stenosis
    View official trial listing →
  • Not yet recruiting NCT NCT07435584

    Everolimus in CDK12-Deficient Metastatic Colorectal Cancer (EVER-RECODE)

    Not yet reported, Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 38 participants Est. completion 2028-12-31
    Other conditions: Colorectal Cancer
    View official trial listing →
  • Not yet recruiting NCT NCT07436611

    Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains

    Not yet reported AFT Pharmaceuticals, Ltd. 30 participants Est. completion 2027-10 2 sites
    Other conditions: Port Wine Stains
    View official trial listing →
  • Active, not recruiting NCT NCT07475546

    Combination Gerotherapeutic Interventions for Healthspan Improvement

    Not yet reported AgelessRx 30 participants Est. completion 2026-04 1 site
    Other conditions: Healthspan Improvement, Aging, Longevity
    View official trial listing →
  • Not yet recruiting NCT NCT07477548

    A Study to Evaluate the Efficacy and Safety of Everolimus in Patients With Teratment-refractory Vascular Anomalies

    Not yet reported Yonsei University 67 participants Est. completion 2030-11-30
    Other conditions: Vascular Malformations, Arteriovenous Malformations, Venous Malformation, Lymphangioma, Nevus, Port-Wine, Hemangioendothelioma, Hemangioma
    View official trial listing →
  • Not yet recruiting NCT NCT07514988

    Sirolimus-Coated vs Paclitaxel-Coated DCBs in ACS Treatment

    Not yet reported China National Center for Cardiovascular Diseases 60 participants Est. completion 2028-07-01 1 site Stand-alone
    Other conditions: Acute Coronary Syndromes (ACS)
    View official trial listing →
  • Not yet recruiting NCT NCT07518277

    A Multicenter, Prospective, Randomized Controlled Study Comparing Glucocorticoid Combined With Sirolimus With Monotherapy of Glucocorticoid in the Treatment of Newly Diagnosed Mild Autoimmune Hemolytic Anemia

    Not yet reported Chen Miao 216 participants Est. completion 2028-04-01 1 site Stand-alone
    Other conditions: Autoimmune Hemolytic Anemia (AIHA)
    View official trial listing →
  • Not yet recruiting NCT NCT07542314

    Study to Evaluate the Safety and Effectiveness of ELEVIDYS in Participants With Duchenne Muscular Dystrophy Treated in a Post-Marketing Setting

    Not yet reported Sarepta Therapeutics, Inc. 20 participants Est. completion 2027-08-31 1 site
    Other conditions: Duchenne Muscular Dystrophy
    View official trial listing →
  • Not yet recruiting NCT NCT07563231

    Polymer-free Sirolimus Eluting Stent: Real-world Investigation of Safety and Outcomes

    Dorian Garin 300 participants Est. completion 2036-06 1 site
    Cardiovascular disease Other conditions: Acute Coronary Syndrome, Stent Thrombosis, Percutaneous Coronary Intervention
    View official trial listing →
  • Not yet recruiting NCT NCT07566091

    Noninferiority Trial Of Sirolimus With Ascorbic Acid Versus Everolimus in All-comers

    Not yet reported Jung-min Ahn 2034 participants Est. completion 2028-06-15 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Not yet recruiting NCT NCT07570433

    HORUS-Cytomegalovirus Open Proof-of-concept Exploratory Trial

    Not yet reported Oriol Manuel 100 participants Est. completion 2028-03 4 sites
    Other conditions: CMV Infection
    View official trial listing →
  • Not yet recruiting NCT NCT07587801

    Vaccination Response Modulation With a Targeted Rapamycin Protocol Study

    Not yet reported Central Adelaide Local Health Network Incorporated 60 participants Est. completion 2026-07 3 sites Stand-alone
    Other conditions: Vaccine Immune Response, Haemodialysis Patients, Older Adults
    View official trial listing →
  • Not yet recruiting NCT NCT07619950

    EVERolimus and LenvAtinib Versus Everolimus for Bone Sarcoma

    Not yet reported Yonsei University 94 participants Est. completion 2028-11-30
    Other conditions: Neoplasms of Bone and Articular Cartilage With Unspecified Anatomical Site
    View official trial listing →
  • Not yet recruiting NCT NCT07634120

    Vertebrobasilar Dolichoectasia Treatment With Sirolimus

    Not yet reported Huashan Hospital 12 participants Est. completion 2027-12 1 site Stand-alone
    Other conditions: Vertebrobasilar Dolichoectasia
    View official trial listing →
  • Not yet recruiting NCT NCT07634601

    Elacestrant With Everolimus for the Treatment of Recurrent Advanced or Metastatic ER-Positive Endometrial Cancer

    Not yet reported Jonsson Comprehensive Cancer Center 50 participants Est. completion 2029-12-18 1 site
    Other conditions: Advanced Endometrial Carcinoma, Metastatic Endometrial Carcinoma, Recurrent Endometrial Carcinoma, Stage III Endometrial Cancer, Stage IV Endometrial Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT07649798

    Initial Study of a MOTHER-DAUGHTER SIDE-BRANCH ACCESS™ DES System (FIH Feasibility Study)

    Not yet reported Advanced Bifurcation Systems Inc. 13 participants Est. completion 2028-11-19 1 site Stand-alone
    Cardiovascular disease Other conditions: Coronary Angioplasty, Ischemic Heart Disease (IHD), Percutaneous Coronary Intervention (PCI)
    View official trial listing →
  • Not yet recruiting NCT NCT07662174

    Ventricular mTOR Inhibition to Prevent Hydrocephalus After Brain Hemorrhage

    Not yet reported, Not yet reported Massachusetts General Hospital 15 participants Est. completion 2027-12-31 1 site Stand-alone
    Other conditions: Post-hemorrhagic Hydrocephalus (PHH)
    View official trial listing →
  • Not yet recruiting NCT NCT07667413

    Topical TOR-582 Treatment of Epistaxis in HHT

    Not yet reported Columbia University 27 participants Est. completion 2027-12 1 site Stand-alone
    Other conditions: Hereditary Hemorrhagic Telangiectasia (HHT), Epistaxis
    View official trial listing →
  • Not yet recruiting NCT NCT07680322

    Safety and Efficacy of AV078 in Participants With Tuberous Sclerosis Complex (TSC) Refractory Epilepsy (RESTOR-1)

    Not yet reported Aeovian Pharmaceuticals, Inc. 42 participants Est. completion 2027-12-21 1 site
    Other conditions: Tuberous Sclerosis Complex, Epilepsy
    View official trial listing →
  • Not yet recruiting NCT NCT07684287

    A Phase 2 Study of Sirolimus for Injection (Albumin-bound) in Patients With Progressive or Symptomatic Epithelioid Hemangioendothelioma

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 40 participants Est. completion 2027-11-30 1 site Stand-alone
    Other conditions: Epithelioid Hemangioendothelioma
    View official trial listing →
  • Available NCT NCT07689942

    Expanded Access to 0.5 mg eRapa for Familial Adenomatous Polyposis

    Biodexa Pharmaceuticals
    Other conditions: Familial Adenomatous Polyposis (FAP)
    View official trial listing →
  • Not yet recruiting NCT NCT07715734

    Cemiplimab for Kidney Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma

    Not yet reported Washington University School of Medicine 22 participants Est. completion 2031-03-31 1 site Stand-alone
    Other conditions: Kidney Transplant Recipient, Cutaneous Squamous Cell Carcinoma (CSCC), Advanced Cutaneous Squamous Cell Carcinoma, Kidney Transplant
    View official trial listing →
  • Not yet recruiting NCT NCT07728175

    Effects of Sirolimus on Asymptomatic ApoE4 Carriers

    Not yet reported University of Missouri-Columbia 225 participants Est. completion 2028-07-07 1 site
    Other conditions: Genetic Predisposition to Disease, Healthy Volunteer, APOE-4 Positive
    View official trial listing →
  • Not yet recruiting NCT NCT07735533

    A Phase 1/2 Study of UB-VV400 With Rapamycin in Relapsed/Refractory B-cell Malignancies

    Not yet reported, Not yet reported Umoja Biopharma 274 participants Est. completion 2031-08 Stand-alone
    Other conditions: Lymphoma, B Cell, Lymphoma Non-Hodgkin, High Grade B Cell Lymphoma, Richter Transformation Lymphoma, Grade 3b Follicular Lymphoma, Primary Mediastinal B Cell Lymphoma, Diffuse Large B Cell Lymphoma (DLBCL)
    View official trial listing →
  • Not yet recruiting NCT NCT07735546

    A Phase 1 Study of UB-VV500 With Rapamycin in Relapsed/Refractory Multiple Myeloma

    Not yet reported Umoja Biopharma 100 participants Est. completion 2029-12-31 Stand-alone
    Other conditions: Multiple Myeloma in Relapse, Multiple Myeloma (MM)
    View official trial listing →
  • Not yet recruiting NCT NCT07739914

    Everolimus bAsed caLcineurin inhibiTor frEe immunosuppRession oNe Year AfTer lIver transplantatiON (ALTERNATION)

    Not yet reported Hannover Medical School 150 participants Est. completion 2031-06-30 16 sites
    Other conditions: Liver Allograft, Liver Diseases, Liver Transplantation
    View official trial listing →
  • Not yet recruiting NCT NCT07767877

    A Study of Clinical Practice and Real-world Care of Patients Treated With mTOR, PI3K, and MEK Inhibitors for Extracranial Vascular Anomalies

    Novartis Pharmaceuticals 200 participants Est. completion 2027-10-29
    Other conditions: Vascular Anomalies
    View official trial listing →
  • Not yet recruiting NCT NCT07796412

    IVUS-Guided Sirolimus-Coated Balloon Versus Sirolimus-Eluting Stent for De Novo Large Vessel Lesions in ACS

    Not yet reported China National Center for Cardiovascular Diseases 150 participants Est. completion 2028-05-01 1 site Stand-alone
    Other conditions: Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
    View official trial listing →
  • Not yet recruiting NCT NCT07796620

    Sirolimus+Ruxolitinib+Mycophenolate Mofetil for Prophylaxis of aGVHD in Patients Receiving Haplo-HSCT Who Are Intolerant to CNI

    Not yet reported, Not yet reported Peking University People's Hospital 40 participants Est. completion 2028-09-30 Stand-alone
    Other conditions: Acute Leukemia, Myelodysplastic Syndromes, Severe Aplastic Anemia (SAA)
    View official trial listing →
  • Not yet recruiting NCT NCT07811232

    A Study of AL58805 in Advanced, Metastatic GYN, STS or Breast Cancers

    Not yet reported, Not yet reported Advenchen Pharmaceuticals, LLC. 138 participants Est. completion 2031-09-01 1 site
    Other conditions: Endometrial Neoplasms, Soft Tissue Sarcoma (STS), Breast Neoplasms
    View official trial listing →
  • Not yet recruiting NCT NCT07811297

    A Study of Catequentinib Hydrochloride (AL3818) in Endometrial, LGSOC, STS or GBM Cancers

    Not yet reported, Not yet reported Advenchen Pharmaceuticals, LLC. 138 participants Est. completion 2031-09-01 1 site
    Other conditions: Endometrial Neoplasms, Ovarian Neoplasms, Soft Tissue Sarcoma (STS), Glioblastoma
    View official trial listing →
  • Not yet recruiting NCT NCT07813533

    A Pilot Study to Examine the Efficacy and Tolerability of Sirolimus on Epidermal Nevi Lesions in Patients 6 Years Old and Above.

    Not yet reported Northwestern University 14 participants Est. completion 2028-12 1 site Stand-alone
    Other conditions: Epidermal Nevi
    View official trial listing →
  • Completed NCT NCT07820579

    Sirolimus Treatment in Pediatric Patients With Ataxia-Telangiectasia

    Not yet reported Sara Elva Espinosa Padilla, MD 6 participants Est. completion 2026-08-20 1 site Stand-alone
    Other conditions: Ataxia-Telangiectasia (A-T), Ataxia-Telangiectasia
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: Sirolimus, Rapamune (sirolimus/rapamycin)

Related On The Pen coverage

No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.