About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
SHR3824
- Company
- Jiangsu HengRui Medicine Co., Ltd.
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 3 recruiting
Efficacy results: Not yet reported
3 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Find a Clinical Trial Near Me
See recruiting studies for SHR3824 and check eligibility with the study team.
Trial details
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Recruiting NCT NCT06818851
The Effects of Henagliflozin on Glucose Fluctuation and Immunosenescence in Type 2 Diabetes Patients on Insulin Therapy
Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 64 participants Est. completion 2028-03-30 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06888050
Efficacy and Safety of Henagliflozin Proline and Metformin Hydrochloride Extended-release Tablets (Ⅰ) Versus Metformin Tablets in Patients With New-onset Type 2 Diabetes: a Multicenter, Randomized Controlled Study
Not yet reported Zhejiang Provincial People's Hospital 268 participants Est. completion 2026-12-30 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06959030
An Observational Study on the Safety and Efficacy of Henagliflozin in Chinese Patients With Type 2 Diabetes
Second Affiliated Hospital of Guangxi Medical University 10000 participants Est. completion 2026-09-01 7 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02346175
Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of SHR3824 in Type 2 Diabetes Mellitus Patients
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 30 participants Est. completion 2014-12 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02353975
Effect of a High-fat Meal on the Pharmacokinetics of SHR3824 and Mass Balance Study in Healthy Subjects
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 12 participants Est. completion 2014-09 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02354027
The Drug-drug Interaction of SHR3824 and Metformin
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 12 participants Est. completion 2015-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02356224
The PK/PD Study of Single Dose of SHR3824 in Healthy Volunteers
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 84 participants Est. completion 2013-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02361138
The PK/PD Study of Multiple Dose of SHR3824 in Healthy Volunteers
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 48 participants Est. completion 2014-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02366351
The PK/PD, Efficacy, Safety and Tolerability Study of SHR3824 in Type 2 Diabetes Mellitus Patients
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 168 participants 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02366377
The PK/PD, Efficacy, Safety and Tolerability Study of SHR3824 in Combination With Metformin in Type 2 Diabetes Mellitus Patients
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 168 participants Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02500485
The Drug-drug Interaction of SHR3824 and SP2086
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 12 participants 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03159052
Efficacy and Safety of SHR3824 as Monotherapy in Subjects With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 450 participants Est. completion 2019-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03159832
Safety and Pharmacokinetics/Pharmacodynamics of SHR3824 in Type 2 Diabetes Patients With Renal Insufficient
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 24 participants Est. completion 2017-12 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03160014
Safety and Pharmacokinetics/Pharmacodynamics of SHR3824 in Patients With Hepatic Impairment
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 32 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: Hepatic ImpairmentView official trial listing → -
Status unknown NCT NCT03329118
Drug-drug Interaction Between Simvastatin and SHR3824
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 12 participants Est. completion 2017-12-08 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04390295
Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 450 participants Est. completion 2020-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05108350
A Study to Assess the Bioequivalence of Fixed Dose Combination of HR20033 Relative to Co-administration of the Individual Components in Healthy Chinese Subjects
Not yet reported Shandong Suncadia Medicine Co., Ltd. 80 participants Est. completion 2021-12-10 Stand-aloneOther conditions: Type II DiabetesView official trial listing → -
Status unknown NCT NCT05252624
Henagliflozin in Patients With Atrial Fibrillation
Not yet reported Beijing Anzhen Hospital 100 participants Est. completion 2023-09-30 1 siteOther conditions: Atrial FibrillationView official trial listing → -
Completed NCT NCT05677334
Combination of Henagliflozin and Continuous Subcutaneous Insulin Infusion in T2DM
Not yet reported First Affiliated Hospital of Guangxi Medical University 210 participants Est. completion 2024-10-30 1 siteOther conditions: Type2diabetesView official trial listing → -
Completed NCT NCT05682495
A HR20031 BE Study on Healthy Subjects
Not yet reported Shandong Suncadia Medicine Co., Ltd. 96 participants Est. completion 2023-04-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05742230
Effect of Henagliflozin on Cardiac Function in Type 2 Diabetes Patients With Chronic Heart Failure (HERO-HF)
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 1932 participants Est. completion 2025-12-31 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT06031389
Henagliflozin Delays the Progress of Diabetic Nephropathy Via Regulates Gut-Renal Axis
Not yet reported Qianfoshan Hospital 120 participants Est. completion 2025-12-31Other conditions: Diabetic NephropathiesView official trial listing → -
Status unknown NCT NCT06059287
The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics
Not yet reported RenJi Hospital 64 participants Est. completion 2025-12-31Type 2 diabetes Other conditions: Obesity, Sodium-glucose Co-transporter-2 Inhibitor, Myocardial Fibrosis, Magnetic Resonance ImagingView official trial listing → -
Completed NCT NCT06083116
Drug-Drug Interaction Study Between Henagliflozin Proline and Hydrochlorothiazide
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 12 participants Est. completion 2019-10-10 1 siteOther conditions: Diabetes in AdultsView official trial listing → -
Completed NCT NCT06085703
Effects of Henagliflozin on the Brain Function in T2DM Patients With Mild Cognitive Impairment: a Randomized, Parallel Controlled Clinical Trial
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 24 participants Est. completion 2025-06-30 1 siteType 2 diabetes Other conditions: Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT06187727
Henagliflozin Reducing Infarct Size After Priamry PCI in Patients With ST Segment Elevation Myocardial Infarction
Not yet reported Qian geng 248 participants Est. completion 2025-10-01 1 siteCardiovascular diseaseHeart failureView official trial listing → -
Not yet recruiting NCT NCT06216340
Efficacy of Henagliflozin for Weight Loss in Obesity Without Diabetes
Not yet reported The First People's Hospital of Changzhou 300 participants Est. completion 2026-10-01Prediabetes Other conditions: Obese, Weight LossView official trial listing → -
Status unknown NCT NCT06218342
Henagliflozin in Relieving Type 2 Diabetes With Non-alcoholic Fatty Liver Disease
Not yet reported Sir Run Run Shaw Hospital 156 participants Est. completion 2025-12-31Type 2 diabetes Other conditions: Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT06221059
Efficacy and Safety of HRS-1780 Tablets and Henagliflozin Proline Tablets in Patients With Chronic Kidney Disease
Not yet reported Shandong Suncadia Medicine Co., Ltd. 181 participants Est. completion 2025-06-24 1 siteChronic kidney diseaseView official trial listing → -
Not yet recruiting NCT NCT06417489
Evaluation of Efficacy and Safety of Combination Therapy of Henagliflozin Proline, Retagliptin and Metformin in New Diagnosed Type 2 Diabetes Patients
Not yet reported Peking University First Hospital 160 participants Est. completion 2026-12-31Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06448130
Henagliflozin's Impact on Prediabetes Remission
Not yet reported Shandong Provincial Hospital 984 participants Est. completion 2027-12 50 sitesPrediabetesType 2 diabetes Other conditions: Prediabetic State, Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT06495931
Study on Drug Interaction of HRS-1780 Tablets, Henagliflozin Tablets, Metformin Tablets and HRS-7535 Tablets in Healthy Human
Not yet reported Shandong Suncadia Medicine Co., Ltd. 24 participants Est. completion 2024-08-13 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06762223
Henagliflozin on Liver Fibrosis in Patients with MASLD and T2DM
Not yet reported Xiqiao Zhou 190 participants Est. completion 2026-12-31 1 site Stand-aloneMASLDType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07027774
Effect of Henagliflozin on Renal Outcomes in Non-dialysis Patients With Advanced Chronic Kidney Disease : A Multicenter Prospective, Randomized Controlled Trial（HERO -aCKD）
Not yet reported First Affiliated Hospital of Wannan Medical College 429 participants Est. completion 2027-12-30Chronic kidney diseaseView official trial listing → -
Not yet recruiting NCT NCT07294495
Effect of Henagliflozin on Myocardial Fibrosis in Non-Obstructive HCM: A Randomized, Double-Blind, Placebo-Controlled Trial Using 68Ga/18F-FAPI PET/CMR
Not yet reported Shanghai East Hospital 150 participants Est. completion 2028-12-31 1 siteOther conditions: HCM - Hypertrophic CardiomyopathyView official trial listing → -
Not yet recruiting NCT NCT07323381
Effects of Henagliflozin Proline and Metformin XR on Body Composition in Geriatric Patients With Newly Diagnosed T2DM
Not yet reported Bin Lu 116 participants Est. completion 2027-09-30Other conditions: Diabetes Type 2View official trial listing → -
Not yet recruiting NCT NCT07441187
Efficacy and Safety of Henagliflozin, Retagliptin, and Metformin Extended-Release Tablets in Chinese Patients With Type 2 Diabetes Mellitus
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 300 participants Est. completion 2027-12-31Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07687212
Randomized Double-blind Controlled Clinical Study of SGLT-2i Combined With Probiotic Preparations in Elderly Patients With HFpEF
Not yet reported, Not yet reported The First Affiliated Hospital of Air Force Medicial University 162 participants Est. completion 2027-11 1 siteHeart failureView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.