About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Semaglutide Treatment
- Company
- University Health Network, Toronto
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 13 recruiting
Efficacy results: Not yet reported
13 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 15, 2026
Find a Clinical Trial Near Me
See recruiting studies for Semaglutide Treatment and check eligibility with the study team.
Trial details
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Recruiting NCT NCT05305794
Effect of Weekly GLP1 Agonist Treatment in "Double Diabetes"
Not yet reported Centre Hospitalier Universitaire Dijon 76 participants Est. completion 2028-08 1 site Added to GLP-1Other conditions: Double DiabetesView official trial listing → -
Recruiting NCT NCT05340868
Genetics of the Acute Response to Oral Semaglutide
Not yet reported Medical University of Bialystok 1000 participants Est. completion 2025-12-31 1 site Added to GLP-1Prediabetes Other conditions: Prediabetic State, ObesityView official trial listing → -
Recruiting NCT NCT05702931
Semaglutide Treatment for Hyperglycaemia After Renal Transplantation
Not yet reported Copenhagen University Hospital, Rigshospitalet 104 participants Est. completion 2027-12 1 siteOther conditions: Hyperglycemia, Renal Transplant Complication Primary Non-Function, DiabetesView official trial listing → -
Recruiting NCT NCT06836284
The Evira Study: Additional Support During Obesity Treatment
Not yet reported Karolinska Institutet 40 participants Est. completion 2027-05-01 3 sitesOther conditions: Childhood Obesity, Treatment AdherenceView official trial listing → -
Recruiting NCT NCT07178145
Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction
Not yet reported University of Virginia 192 participants Est. completion 2029-12 1 siteHeart failure Other conditions: Epicardial Adipose TissueView official trial listing → -
Recruiting NCT NCT07187830
Visceral Adipose Tissue and Liver Changes Associated With Semaglutide in CKD
University of Alberta 52 participants Est. completion 2028-01-15 1 siteType 2 diabetesChronic kidney disease Other conditions: Obesity & OverweightView official trial listing → -
Recruiting NCT NCT07302802
Efficacy of Semaglutide s.c. Once-weekly on Weight Loss and Management in Adolescents With Monogenic Obesity in Clinical Practice
Prof. Dr. Martin Wabitsch 70 participants Est. completion 2028-12 7 sitesOther conditions: Monogenic ObesityView official trial listing → -
Recruiting NCT NCT07336862
Bariatric Surgery Combined With GLP-1 Receptor Agonists Study
Not yet reported, Not yet reported China-Japan Friendship Hospital 200 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07374328
Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Second Affiliated Hospital of Guangzhou Medical University 240 participants Est. completion 2026-08-31 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Recruiting NCT NCT07478653
MODERN-Dental: Pediatric Obesity, Cardiometabolic Risks, And Periodontal Disease
Not yet reported Oelisoa Andriankaja 50 participants Est. completion 2028-07-31 1 siteOther conditions: Obesity, Dental Care for ChildrenView official trial listing → -
Recruiting NCT NCT07633639
GLP-1 Therapy After Bariatric Surgery in Chinese Patients With Obesity
Not yet reported China-Japan Friendship Hospital 200 participants Est. completion 2028-05-01 1 site Added to GLP-1Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT07732426
Effects of Semaglutide on Brain Dopamine Responses to Food Cues in Adults With Obesity and Food Addiction Tendencies
Not yet reported Seoul National University Hospital 30 participants Est. completion 2028-06-30 1 site Added to GLP-1Other conditions: Food Addiction Tendency, Obesity, OverweightView official trial listing → -
Recruiting NCT NCT07732738
Bariatric Surgery Combined With GLP-1RA: A Multicenter Study.
Not yet reported China-Japan Friendship Hospital 400 participants Est. completion 2027-12-30 7 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT02022254
Influence of Semaglutide on Pharmacokinetics and Pharmacodynamics of Warfarin and Pharmacokinetics of Metformin in Healthy Subjects
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2014-08-28 1 site Added to GLP-1Type 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02064348
A Thorough QTc Evaluation of the Effect of Semaglutide on Cardiac Repolarisation in Healthy Subjects
Not yet reported Novo Nordisk A/S 168 participants Est. completion 2015-04-23 1 site Added to GLP-1Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT03574597
Semaglutide Effects on Heart Disease and Stroke in Patients With Overweight or Obesity
Not yet reported Novo Nordisk A/S 17604 participants Est. completion 2023-06-29 833 sites Added to GLP-1Other conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT03789578
A Research Study to Look at How Insulin 287 and Semaglutide Work in the Body of People With Type 2 Diabetes When Taken Alone or Together
Not yet reported Novo Nordisk A/S 30 participants Est. completion 2019-10-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03985384
Semaglutide Treatment On Coronary Progression
Not yet reported Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center 140 participants Est. completion 2022-12-27 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT04383197
Exercise and GLP-1 RA on Insulin Secretion
Not yet reported University of Copenhagen 30 participants Est. completion 2022-08 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT04596631
A Research Study to Compare a New Medicine Oral Semaglutide to a Dummy Medicine in Children and Teenagers With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 132 participants Est. completion 2026-02-03 97 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT05193578
Home-based Intervention With Semaglutide Treatment Of Neuroleptica-Related Prediabetes
Not yet reported Jan Frystyk 154 participants Est. completion 2024-05-01 1 siteOther conditions: Schizophrenia, Prediabetic StateView official trial listing → -
Active, not recruiting NCT NCT05195944
Semaglutide vs Sitagliptin
Not yet reported University Health Network, Toronto 58 participants Est. completion 2026-12 1 site Added to GLP-1MASHMASLD Other conditions: Liver Transplant; Complications, Diabetes MellitusView official trial listing → -
Completed NCT NCT05371496
Cardiac and Metabolic Effects of Semaglutide in Heart Failure With Preserved Ejection Fraction
Not yet reported Mayo Clinic 81 participants Est. completion 2026-07-17 1 siteHeart failure Other conditions: Cardiomyopathy, ObesityView official trial listing → -
Completed NCT NCT05537233
ADJUnct Semaglutide Treatment in Type 1 Diabetes
Not yet reported Viral N. Shah 115 participants Est. completion 2024-08-06 4 sitesOther conditions: Type 1 Diabetes, ObesityView official trial listing → -
Completed NCT NCT05548647
Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects
Not yet reported University of Pennsylvania 120 participants Est. completion 2025-05-12 1 siteOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT05597202
Does the Hematopoietic Stem Cell Govern Residual Inflammatory Cardiovascular Risk in Type 2 Diabetes
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 22 participants Est. completion 2024-04 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT05716724
O-SEMA-Fast: A Research Study to Understand How Oral Semaglutide Works in People With Type 2 Diabetes Who Plan to Fast During Ramadan in the United Arab Emirates, Saudi Arabia, and Kuwait
Novo Nordisk A/S 288 participants Est. completion 2023-07-09 20 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05751226
A Study in People With Overweight or Obesity to Test How Well Different Doses of BI 1820237 Are Tolerated When Given Alone or in Combination With Either Semaglutide or BI 456906
Not yet reported Boehringer Ingelheim 88 participants Est. completion 2024-08-01 1 site Added to GLP-1Other conditions: Healthy, ObesityView official trial listing → -
Active, not recruiting NCT NCT06005012
Semaglutide Treatment in the Real-world for Fibrosis Due to NAFLD in Obesity and T2DM
Not yet reported University of California, San Diego 120 participants Est. completion 2026-12-31 1 siteType 2 diabetes Other conditions: Fibrosis, Liver, Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Active, not recruiting NCT NCT06042153
DIALYSIS-TIR Study
Not yet reported University of Texas Southwestern Medical Center 43 participants Est. completion 2028-09 5 sites Added to GLP-1Type 2 diabetes Other conditions: End Stage Renal Disease on DialysisView official trial listing → -
Completed NCT NCT06221696
Preventing Weight Regain Post-Semaglutide Treatment With Active Fiber Supplement (Soloways)
Not yet reported S.LAB (SOLOWAYS) 160 participants Est. completion 2023-12-01 1 siteOther conditions: Overweight and ObesityView official trial listing → -
Completed NCT NCT06390501
The Effect of Weekly Semaglutide Treatment on Energy Expenditure
Not yet reported Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences 60 participants Est. completion 2025-09-15 1 siteOther conditions: Obesity; DrugView official trial listing → -
Not yet recruiting NCT NCT06449625
Semaglutide in Auto-HSCT
Not yet reported Klaus Gottlob Müller 40 participants Est. completion 2027-02-01Other conditions: Intestinal Mucositis, Inflammation, Chemotherapeutic ToxicityView official trial listing → -
Withdrawn NCT NCT06468748
The Effects of Semaglutide on Body Composition and Performance in Military Personnel
Not yet reported United States Army Research Institute of Environmental Medicine Est. completion 2025-03-27 1 site Added to GLP-1Other conditions: ObesityView official trial listing → -
Completed NCT NCT06489457
The Effects of Semaglutide vs Testosterone Replacement Therapy on Functional Hypogonadism and Sperm Quality in Men With Type 2 Diabetes Mellitus and Obesity
Not yet reported University Medical Centre Ljubljana 25 participants Est. completion 2023-06-30 1 site Added to GLP-1Type 2 diabetes Other conditions: Obesity, Functional HypogonadismView official trial listing → -
Completed NCT NCT06856291
Response to Semaglutide in Non-diabetic Obese Patients With Varying Degrees of Insulin Resistance
ETH Zurich 40 participants Est. completion 2026-09-06 1 siteOther conditions: Obesity and Obesity-related Medical Conditions, Obesity and Overweight, Insulin Sensitivity/Resistance, SemaglutideView official trial listing → -
Not yet recruiting NCT NCT06909006
Semaglutide Treatment in Type 1 Diabetes
Not yet reported Nordsjaellands Hospital 122 participants Est. completion 2028-06 1 siteOther conditions: Obesity in Diabetes, Obesity/Therapy, Type 1 Diabetes Mellitus (T1DM), Insulin Sensitivity/Resistance, Semaglutide, Lipidomics, Metabolomics, Weight Loss, Glycemic Control for Diabetes MellitusView official trial listing → -
Completed NCT NCT07171723
Studying the Influence of LEAP2 on Integrated Endocrine Control of Eating During Semaglutide Treatment
Not yet reported, Not yet reported University Hospital, Gentofte, Copenhagen 24 participants Est. completion 2026-08-12 1 siteOther conditions: Obesity &Amp; OverweightView official trial listing → -
Completed NCT NCT07190144
Coronary Flow Reserve Changes After Semaglutide Treatment
Ekrem Bilal Karaayvaz 122 participants Est. completion 2025-08-01 1 siteOther conditions: The Study Focused on the Vascular Effects of Semaglutide in Both Diabetic and Non-diabetic Patients, Obesity &Amp; OverweightView official trial listing → -
Active, not recruiting NCT NCT07223983
Semaglutide (SEMA) for Alcohol Use Disorder (AUD) After Metabolic and Bariatric Surgery (MBS)
Not yet reported Yale University 4 participants Est. completion 2027-02 1 siteAlcohol use disorder Other conditions: Weight Loss, Bariatric Surgery PatientsView official trial listing → -
Completed NCT NCT07281196
Semaglutide Effects on Sleep Apnea in Patients With Type 2 Diabetes/Obesity and Comorbid Obstructive Sleep Apnea
Shanghai Fengxian District Central Hospital 15 participants Est. completion 2026-01-31 1 siteObstructive sleep apneaView official trial listing → -
Not yet recruiting NCT NCT07282769
Semaglutide (Wegovy) Treatment for Trichotillomania
Not yet reported University of Chicago 10 participants Est. completion 2027-02Other conditions: Trichotillomania (Hair-Pulling Disorder), Trichotillomania, Hair Pulling Disorder, Hair Pulling, Hair-Pulling DisorderView official trial listing → -
Not yet recruiting NCT NCT07430332
GLP-1 RA for Stage 1 Type 1 Diabetes
Not yet reported Children's Hospital Medical Center, Cincinnati 15 participants Est. completion 2030-01-01 1 site Added to GLP-1Other conditions: Stage 1 Diabetes Mellitus, Type 1View official trial listing → -
Active, not recruiting NCT NCT07457424
Direct Measurement of Microstructure of Ingestive Behaviour After Initiation of GLP-1 Receptor Agonist Treatment at Maximum Dose (DIGRAT)
University College Dublin 140 participants Est. completion 2027-01-31 1 siteOther conditions: Metabolic Disease, Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07621640
Brown Adipose Tissue as a Mechanistic Determinant of Semaglutide Treatment Response in Obesity (BAT-Sema Study)
Not yet reported Hallym University 80 participants Est. completion 2031-02 2 sitesMetabolic syndrome Other conditions: Obesity, Brown Adipose TissueView official trial listing → -
Not yet recruiting NCT NCT07820722
Assessing Heart and Brain Metabolism in Type II Diabetes Mellitus Patients Using Carbon-13 MRI
Not yet reported Sunnybrook Health Sciences Centre 32 participants Est. completion 2029-08-01 Added to GLP-1Other conditions: Diabete Type 2View official trial listing → -
Completed NCT NCT07847593
Probiotics in Obese Patients Treated With Semaglutide
Not yet reported Nordic Biotic Sp. z o.o. 102 participants Est. completion 2026-07-15 3 sites Stand-aloneType 2 diabetes Other conditions: Obesity (Disorder), GLP-1 Receptor Agonist Treatment, Probiotic InterventionView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.