About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Ritlecitinib
- Company
- Massachusetts General Hospital
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 8 recruiting
Efficacy results: Not yet reported
8 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 16, 2026
Find a Clinical Trial Near Me
See recruiting studies for Ritlecitinib and check eligibility with the study team.
Trial details
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Recruiting NCT NCT06373458
Ritlecitinib in Patients With Keloids or Those Undergoing Keloidectomy
Not yet reported Icahn School of Medicine at Mount Sinai 30 participants Est. completion 2028-01 1 site Stand-aloneOther conditions: KeloidView official trial listing → -
Recruiting NCT NCT06573593
Efficacy and Safety of JAK Inhibitors in Patients With AA: RWE Study
Second Affiliated Hospital, Zhejiang University, School of Medicine 150 participants Est. completion 2026-12-31 1 siteOther conditions: Alopecia Areata, Janus Kinase InhibitorsView official trial listing → -
Recruiting NCT NCT06873945
A Study of 2 Doses of Ritlecitinib in People 12 Years of Age and Older With Alopecia Areata
Not yet reported Pfizer 1330 participants Est. completion 2028-03-19 146 sites Stand-aloneOther conditions: Alopecia AreataView official trial listing → -
Recruiting NCT NCT07029828
A Long-Term Study to Learn About The Study Medicine Called Ritlecitinib in Children With Severe Alopecia Areata.
Not yet reported Pfizer 140 participants Est. completion 2030-06-26 41 sites Stand-aloneOther conditions: Severe Alopecia AreataView official trial listing → -
Recruiting NCT NCT07152119
A Study to Learn About Litfulo Capsule in People With Severe Alopecia Areata in Routine Clinical Practice.
Pfizer 3000 participants Est. completion 2030-03-23 1 siteOther conditions: Severe Alopecia AreataView official trial listing → -
Recruiting NCT NCT07152626
Combination Approach With Ritlecitinib and nbUVB Compared to Ritlecitinib Alone for Treating Vitiligo
Not yet reported Centre Hospitalier Universitaire de Nice 56 participants Est. completion 2029-06-01 5 sites Stand-aloneOther conditions: VitiligoView official trial listing → -
Recruiting NCT NCT07219615
A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.
Not yet reported Pfizer 200 participants Est. completion 2027-04-23 69 sites Stand-aloneOther conditions: Chronic Spontaneous UrticariaView official trial listing → -
Recruiting NCT NCT07733765
A Study in Young People and Adults to Learn About the Medicine Ritlecitinib for Treatment of Patchy Hair Loss, Known by the Medical Term as Moderate Alopecia Areata
Not yet reported Pfizer 336 participants Est. completion 2028-04-26 20 sites Stand-aloneOther conditions: Alopecia AreataView official trial listing → -
Completed NCT NCT03732807
PF-06651600 for the Treatment of Alopecia Areata
Not yet reported, Not yet reported Pfizer 718 participants Est. completion 2021-06-24 155 sitesOther conditions: Alopecia AreataView official trial listing → -
Completed NCT NCT04006457
Long-Term PF-06651600 for the Treatment of Alopecia Areata
Not yet reported Pfizer 1057 participants Est. completion 2026-02-26 144 sitesOther conditions: Alopecia AreataView official trial listing → -
Completed NCT NCT04413617
TO ASSESS THE EFFICACY AND SAFETY OF PF-06650833, PF-06651600, AND TOFACITINIB ALONE AND IN COMBINATION IN PARTICIPANTS WITH ACTIVE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATE
Not yet reported Pfizer 460 participants Est. completion 2022-02-07 144 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT04517864
PLACEBO-CONTROLLED SAFETY STUDY OF RITLECITINIB (PF-06651600) IN ADULTS WITH ALOPECIA AREATA
Not yet reported Pfizer 71 participants Est. completion 2024-05-07 38 sites Stand-aloneOther conditions: Alopecia AreataView official trial listing → -
Completed NCT NCT04655040
Estimation of the Effect of Multiple Dose Ritlecitinib (PF-06651600) on the Pharmacokinetics of a Single Dose of Caffeine in Healthy Participants
Not yet reported Pfizer 12 participants Est. completion 2021-03-05 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT05040295
A Single Dose Study To Test Two Pediatric Forms Of Ritlecitinib Compared With Adult Ritlecitinib In Healthy Adults
Not yet reported Pfizer 12 participants Est. completion 2021-11-19 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT05097716
Study to Evaluate the Effect of Multiple-Dose Ritlecitinib on the Pharmacokinetics (PK) of Tolbutamide
Not yet reported Pfizer 12 participants Est. completion 2022-01-10 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT05128058
A Target Occupancy Study With Ritlecitinib.
Not yet reported Pfizer 16 participants Est. completion 2022-01-14 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Available NCT NCT05522556
Pre-approval Single-patient Expanded Access for Ritlecitinib (PF-06651600)
PfizerOther conditions: Alopecia AreataView official trial listing → -
Completed NCT NCT05549934
Ritlecitinib for Cicatricial Alopecia
Not yet reported Emma Guttman 50 participants Est. completion 2025-03-20 1 site Stand-aloneOther conditions: Cicatricial AlopeciaView official trial listing → -
Completed NCT NCT05583526
A 52-Week Study of Ritlecitinib Oral Capsules in Adults and Adolescents With Nonsegmental Vitiligo (Active and Stable) Tranquillo
Not yet reported Pfizer 607 participants Est. completion 2026-02-05 115 sites Stand-aloneOther conditions: Stable Nonsegmental Vitiligo, Active Nonsegmental VitiligoView official trial listing → -
Completed NCT NCT05636293
Double Blind, Placebo-controlled Trial to Establish Safety and Efficacy of Ritlecitinib in Celiac Disease Patients in Remission
Not yet reported Massachusetts General Hospital 62 participants Est. completion 2026-04-09 1 siteOther conditions: Celiac DiseaseView official trial listing → -
Completed NCT NCT05650333
A Study to Learn About the Study Medicine (Called Ritlecitinib) For the Potential Treatment of Severe Alopecia Areata (AA) In Children 6 To Less Than 12 Years of Age
Not yet reported Pfizer 15 participants Est. completion 2023-08-11 9 sites Stand-aloneOther conditions: Alopecia AreataView official trial listing → -
Active, not recruiting NCT NCT05743244
Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D)
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 78 participants Est. completion 2027-10-30 30 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT05852340
A Study to Assess Two Forms of The Study Medicine (Ritlecitinib) in Healthy Adult Participants
Not yet reported Pfizer 12 participants Est. completion 2023-07-24 1 siteOther conditions: Healthy Volunteers, Adult, PharmacokineticsView official trial listing → -
Terminated NCT NCT05879458
Ritlecitinib in CTCL
Not yet reported Icahn School of Medicine at Mount Sinai 7 participants Est. completion 2025-06-25 1 site Stand-aloneOther conditions: CTCL, Mycosis Fungoides, Sezary SyndromeView official trial listing → -
Active, not recruiting NCT NCT06072183
A 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranquillo 2
Not yet reported Pfizer 1571 participants Est. completion 2027-07-30 229 sites Stand-aloneOther conditions: Stable Nonsegmental Vitiligo, Active Nonsegmental VitiligoView official trial listing → -
Active, not recruiting NCT NCT06163326
A 52-Week Study to Learn About the Safety and Effects of Ritlecitinib in Participants With Nonsegmental Vitiligo
Not yet reported Pfizer 394 participants Est. completion 2027-03-31 73 sites Stand-aloneOther conditions: VitiligoView official trial listing → -
Completed NCT NCT06172348
A Study to Learn About Three Forms of The Study Medicine (Ritlecitinib) in Healthy Adults
Not yet reported Pfizer 12 participants Est. completion 2024-03-28 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Active, not recruiting NCT NCT06279221
Litfulo Capsules Special Investigation
Pfizer 664 participants Est. completion 2030-01-18 1 siteOther conditions: Alopecia AreataView official trial listing → -
Completed NCT NCT06369454
A Study to Learn About How Different Forms of the Study Medicine Called Ritlecitinib Pass the Intestines of Healthy Male Adults When Taken With or Without Food
Not yet reported Pfizer 12 participants Est. completion 2024-07-31 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Active, not recruiting NCT NCT06531109
Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib
Pfizer 450 participants Est. completion 2028-04-15 70 sitesOther conditions: Alopecia AreataView official trial listing → -
Withdrawn NCT NCT06795373
Ritlecitinib (PF-06651600) in Participants With Chronic Spontaneous Urticaria
Not yet reported Ahuva D Cices Est. completion 2026-03-31 1 site Stand-aloneOther conditions: Chronic Spontaneous Urticaria, CSUView official trial listing → -
Active, not recruiting NCT NCT07029711
A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata
Not yet reported Pfizer 208 participants Est. completion 2027-01-06 83 sites Stand-aloneOther conditions: Severe Alopecia AreataView official trial listing → -
Completed NCT NCT07200128
A Study to Learn About the Medicine Called Ritlecitinib in Adults With Severe Alopecia Areata in Real-world Settings
Pfizer 123 participants Est. completion 2025-05-30 1 siteOther conditions: Severe Alopecia AreataView official trial listing → -
Completed NCT NCT07226531
Utilization and Effectiveness of Ritlecitinib in a Real-World Population With Severe AA in the US
Pfizer 300 participants Est. completion 2026-03-06 1 siteOther conditions: Alopecia AreataView official trial listing → -
Active, not recruiting NCT NCT07228390
A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.
Not yet reported Pfizer 128 participants Est. completion 2027-01-05 67 sites Stand-aloneOther conditions: Hidradenitis SuppurativaView official trial listing → -
Not yet recruiting NCT NCT07821216
Real-World Effectiveness of Ritlecitinib in Alopecia Areata Patients in the US: A Retrospective Analysis Using EHR and Claims Data
Pfizer 7500 participants Est. completion 2027-04-20Other conditions: Alopecia AreataView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Ritlecitinib, Litfulo
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
