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Recruiting
NCT NCT07212868
The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery
Not yet reported
The University of Texas Health Science Center at San Antonio
150 participants
Est. completion 2030-06-30
2 sites
Stand-alone
Other conditions: Non-Diabetic
View official trial listing →
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Completed
NCT NCT02455011
Dose Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of REMD-477 in Subjects With Type 2 Diabetes Mellitus
Not yet reported, Not yet reported
REMD Biotherapeutics, Inc.
75 participants
Est. completion 2018-02
3 sites
Stand-alone
Type 2 diabetes
Other conditions: Diabetes
View official trial listing →
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Completed
NCT NCT02715193
Single-dose Study to Evaluate Safety, Tolerability, and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus
Not yet reported
REMD Biotherapeutics, Inc.
21 participants
Est. completion 2017-01
2 sites
Stand-alone
Other conditions: Type 1 Diabetes Mellitus, Diabetes
View official trial listing →
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Completed
NCT NCT03117998
Multiple Dose Study to Evaluate the Efficacy, Safety and Pharmacodynamics of REMD-477 in Subjects With Type 1 Diabetes Mellitus
Not yet reported
REMD Biotherapeutics, Inc.
154 participants
Est. completion 2021-03-05
11 sites
Stand-alone
Other conditions: Type1 Diabetes Mellitus
View official trial listing →
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Completed
NCT NCT03919617
Metabolic Pathways of GRA in Patients With Type 1 Diabetes
Not yet reported, Not yet reported
University of California, San Diego
4 participants
Est. completion 2022-05-31
1 site
Stand-alone
Other conditions: Type 1 Diabetes Mellitus
View official trial listing →
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Terminated
NCT NCT04253223
A Study to Determine Safety and Efficacy of (REMD-477) in Controlling Hyperglycemia Due to Copanlisib
Not yet reported
Duke University
1 participants
Est. completion 2021-05-05
1 site
Stand-alone
Other conditions: Hyperglycemia Drug Induced
View official trial listing →
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Terminated
NCT NCT04330625
Glucagon Receptor Inhibition to Enable Breast Cancer Patients to Benefit From PI3K Inhibitor Therapy (REMD-477)
Not yet reported
Duke University
1 participants
Est. completion 2021-05-05
1 site
Stand-alone
Other conditions: Hyperglycemia Drug Induced
View official trial listing →
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Completed
NCT NCT04545411
Combination GRA and SGLT-2i Treatment in Type 1 Diabetes
Not yet reported, Not yet reported
University of California, San Diego
12 participants
Est. completion 2022-10-31
1 site
Other conditions: Type 1 Diabetes
View official trial listing →
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Active, not recruiting
NCT NCT04779645
Effects of GRA in Patients With Type 1
Not yet reported
University of California, San Diego
30 participants
Est. completion 2025-12-31
1 site
Stand-alone
Other conditions: Type 1 Diabetes
View official trial listing →
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Completed
NCT NCT05093517
Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM
Not yet reported
The University of Texas Health Science Center at San Antonio
4 participants
Est. completion 2022-03-16
1 site
Stand-alone
Type 2 diabetes
Other conditions: Glucose Tolerance Impaired, Insulin Sensitivity
View official trial listing →