GLP-1 Market
LLY $1188.72 ▲ +2.7% NVO $38.26 ▲ +1.9% PFE $28.00 ▲ +1.8% VKTX $28.54 ▲ +0.6% KLRA $10.53 ▼ -2.8% GPCR $26.68 ▼ -2.9% RHHBY $53.97 ▲ +2.7%
Market data delayed up to 20 min · Source: Twelve Data

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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Prazosin Hydrochloride

Company
VA Office of Research and Development
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
2 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

2 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Oct 8, 2026

Find a Clinical Trial Near Me

See recruiting studies for Prazosin Hydrochloride and check eligibility with the study team.

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Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT06629077

    Brain Blood Vessel Responses to Changes in Blood Flow

    Not yet reported University of Wisconsin, Madison 36 participants Est. completion 2027-05 1 site Stand-alone
    Other conditions: Magnetic Resonance Imaging, Cerebrovascular Circulation
    View official trial listing →
  • Recruiting NCT NCT06629090

    Brain Blood Vessel Responses to Changes in Blood Flow: Younger Cohort

    Not yet reported University of Wisconsin, Madison 36 participants Est. completion 2027-05 1 site Stand-alone
    Other conditions: Magnetic Resonance Imaging, Cerebrovascular Circulation
    View official trial listing →
  • Completed NCT NCT00000522

    Treatment of Mild Hypertension Study (TOMHS)

    Not yet reported University of Minnesota Est. completion 1994-05
    Cardiovascular disease Other conditions: Heart Diseases, Hypertension, Vascular Diseases
    View official trial listing →
  • Completed NCT NCT00000542

    Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

    Not yet reported National Heart, Lung, and Blood Institute (NHLBI) Est. completion 2002-03
    Cardiovascular diseaseHeart failure Other conditions: Coronary Disease, Diabetes Mellitus, Heart Diseases, Hypercholesterolemia, Hypertension, Myocardial Ischemia
    View official trial listing →
  • Completed NCT NCT00006294

    Genetics of Hypertension Associated Treatments (GenHAT)

    Donna Arnett, 257-5678 37939 participants Est. completion 2005-08 1 site
    Cardiovascular disease Other conditions: Heart Diseases, Hypertension, Coronary Disease
    View official trial listing →
  • Completed NCT NCT00021814

    Medical Therapy of Prostatic Symptoms

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 3407 participants Est. completion 2001-11-30 17 sites
    Other conditions: Prostatic Hyperplasia, Prostatic Hypertrophy, Benign
    View official trial listing →
  • Completed NCT NCT00108420

    Prazosin Treatment for Combat Trauma PTSD (Post-Traumatic Stress Disorder) Nightmares and Sleep Disturbance

    Not yet reported US Department of Veterans Affairs Est. completion 2007-03 1 site
    Other conditions: Stress Disorder, Post-Traumatic
    View official trial listing →
  • Completed NCT NCT00130156

    Effects of Combination Therapy With Alpha-1 Blocker (Bunazosin or Doxazosin) in the Treatment of Patients With Mild to Moderate Essential Hypertension

    Not yet reported Eisai Inc. 93 participants Est. completion 2009-03 1 site
    Other conditions: High Blood Pressure
    View official trial listing →
  • Terminated NCT NCT00141596

    Extracellular Fluid in Resistant Hypertension

    Not yet reported St George's, University of London 32 participants Est. completion 2006-10 1 site
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT00148837

    Efficacy of Prazosin Versus Placebo Associated With Peg-interferon Alpha 2b and Ribavirin in Chronic Hepatitis C With Genotype 1 or 4 and Severe Fibrosis

    Not yet reported French National Agency for Research on AIDS and Viral Hepatitis 112 participants Est. completion 2008-12 1 site Stand-alone
    Other conditions: Hepatitis C, Chronic, Fibrosis
    View official trial listing →
  • Completed NCT NCT00161473

    Alzheimer's in Long-Term Care--Treatment for Agitation

    Not yet reported University of Washington 24 participants Est. completion 2009-09 1 site
    Other conditions: Alzheimer Disease, Psychomotor Agitation
    View official trial listing →
  • Completed NCT NCT00167687

    Prazosin Alcohol Dependence IVR Study

    Not yet reported University of Washington 23 participants Est. completion 2007-10 1 site
    Other conditions: Alcoholism
    View official trial listing →
  • Status unknown NCT NCT00174551

    Feasibility Study: The Effect of Prazosin for Nighttime Symptoms of Civilian PTSD

    Not yet reported Rainier Associates 20 participants Est. completion 2005-11 1 site
    Other conditions: Stress Disorders, Post-Traumatic
    View official trial listing →
  • Completed NCT NCT00175682

    Prazosin Vibrostimulation Autonomic Dysreflexia and Spinal Cord Injury Study

    Not yet reported University of British Columbia 7 participants Est. completion 2011-07-28 1 site
    Other conditions: Autonomic Dysreflexia
    View official trial listing →
  • Terminated NCT NCT00183430

    Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder

    Not yet reported Seattle Institute for Biomedical and Clinical Research 20 participants Est. completion 2010-12 1 site Stand-alone
    Other conditions: Post-Traumatic Stress Disorder, Sleep Initiation and Maintenance Disorders
    View official trial listing →
  • Terminated NCT NCT00202449

    Prazosin vs Paroxetine in Combat Stress-Related Post-Traumatic Stress Disorder (PTSD) Nightmares & Sleep Disturbance

    Not yet reported Seattle Institute for Biomedical and Clinical Research 59 participants Est. completion 2008-02 2 sites Stand-alone
    Other conditions: Stress Disorders, Post-Traumatic, Sleep Disorders
    View official trial listing →
  • Completed NCT NCT00223717

    Treatment of Supine Hypertension in Autonomic Failure

    Not yet reported Vanderbilt University 152 participants Est. completion 2017-01 1 site Stand-alone
    Other conditions: Hypertension
    View official trial listing →
  • Terminated NCT NCT00240227

    Prazosin for ETOH or Cocaine Craving

    Not yet reported US Department of Veterans Affairs 8 participants Est. completion 2009-01 1 site
    Other conditions: Alcoholism, Cocaine Dependence
    View official trial listing →
  • Completed NCT NCT00261729

    Prazosin vs. Paroxetine in Combat Stress Symptoms in OIF/OEF Returnees

    Not yet reported US Department of Veterans Affairs 210 participants Est. completion 2009-12 1 site Stand-alone
    Other conditions: Sleep Disorders, Stress Disorders, Post-Traumatic
    View official trial listing →
  • Completed NCT NCT00285519

    Japan Morning Surge-1 Study

    Not yet reported Japan Heart Foundation 600 participants Est. completion 2005-08 1 site
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT00295542

    Ambulatory Blood Pressure Monitoring in the Prediction of Cardiovascular Events and Effects of Chronotherapy

    Not yet reported University of Vigo 3344 participants Est. completion 2009-04 1 site
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT00393874

    Efficacy of Sleep Interventions for Posttraumatic Stress Disorder (PTSD)

    Not yet reported University of Pittsburgh 50 participants Est. completion 2011-06 1 site
    Other conditions: Anxiety Disorders, Mood Disorders, Insomnia, Nightmares
    View official trial listing →
  • Terminated NCT NCT00424801

    Effects of Intensive Long-Term Vasodilation in Hypertensive Patients With Microvascular Angina Pectoris

    Not yet reported University of Aarhus 10 participants Est. completion 2008-12 1 site
    Other conditions: Microvascular Angina, Hypertension
    View official trial listing →
  • Completed NCT NCT00450164

    Secondary Prophylaxis After Variceal Bleeding in Non-Responders

    Not yet reported Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 50 participants Est. completion 2004-06 1 site
    Other conditions: Gastrointestinal Hemorrhage, Portal Hypertension, Cirrhosis
    View official trial listing →
  • Completed NCT NCT00487032

    Differential Adrenoreceptor Mediated Tachyphylaxis and Upregulation

    Not yet reported Brian J Lipworth 19 participants Est. completion 2009-05 2 sites Stand-alone
    Obstructive sleep apnea Other conditions: Allergic Rhinitis, Tachyphylaxis
    View official trial listing →
  • Completed NCT NCT00532493

    Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD

    Not yet reported VA Office of Research and Development 304 participants Est. completion 2013-05-31 15 sites
    Other conditions: PTSD, Sleep Disorders
    View official trial listing →
  • Completed NCT NCT00535925

    Nephropathy In Type 2 Diabetes and Cardio-renal Events

    Not yet reported University of Campania Luigi Vanvitelli 850 participants Est. completion 2019-05 1 site
    Chronic kidney disease
    View official trial listing →
  • Terminated NCT NCT00563485

    Randomized Trial Comparing Terazosin 5 mg Daily and Doxazosin GITS 4 mg Daily for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up

    Not yet reported Hospital Authority, Hong Kong 120 participants Est. completion 2006-11 1 site
    Other conditions: Prostatic Hyperplasia, Urinary Retention
    View official trial listing →
  • Status unknown NCT NCT00563602

    Treatment for Prevention of Variceal Rebleeding Guided by the Hemodynamic Response

    Not yet reported Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 140 participants Est. completion 2007-11 1 site Stand-alone
    Other conditions: Portal Hypertension, Complications of Cirrhosis
    View official trial listing →
  • Completed NCT NCT00585780

    Prazosin to Reduce Stress-Induced Alcohol/Drug Craving and Relapse

    Not yet reported, Not yet reported Yale University 100 participants Est. completion 2019-05-13 1 site
    Alcohol use disorder
    View official trial listing →
  • Status unknown NCT NCT00602186

    Effect of Tamsulosin vs Prazosin in Treatment of Female Voiding Dysfunction

    Not yet reported, Not yet reported Tabriz University 80 participants Est. completion 2008-03
    Other conditions: Neurogenic Bladder
    View official trial listing →
  • Completed NCT NCT00661895

    Black Education and Treatment of Hypertension (BEAT HTN)

    Not yet reported Creighton University 99 participants Est. completion 2009-11 1 site
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT00684489

    Renin-Guided Therapeutics in the Management of Untreated, Uncontrolled, or Complicated Hypertension

    Not yet reported Medical University of South Carolina 52 participants Est. completion 2005-09
    Other conditions: Hypertension
    View official trial listing →
  • Withdrawn NCT NCT00687388

    The Clinical Efficacy of Non-steroidal Anti-inflammation Drugs in Patients With Benign Prostatic Hyperplasia

    Not yet reported Samsung Medical Center 3 sites
    Other conditions: Benign Prostatic Hyperplasia
    View official trial listing →
  • Status unknown NCT NCT00713739

    Alfuzosin for Medical Expulsion Therapy of Ureteral Stones

    Not yet reported United States Naval Medical Center, San Diego 240 participants Est. completion 2012-12 1 site Stand-alone
    Other conditions: Kidney Stones
    View official trial listing →
  • Completed NCT NCT00730418

    Effects of Chronic Use of Doxazosin in Men With Benign Prostatic Hyperplasia

    Not yet reported Samsung Medical Center 25 participants Est. completion 2010-03 1 site
    Other conditions: Benign Prostatic Hyperplasia
    View official trial listing →
  • Completed NCT NCT00741585

    Prognostic Value of the Circadian Pattern of Ambulatory Blood Pressure for Multiple Risk Assessment

    Not yet reported University of Vigo 21983 participants Est. completion 2018-06-30 20 sites
    Cardiovascular diseaseChronic kidney disease Other conditions: Essential Hypertension
    View official trial listing →
  • Completed NCT NCT00744055

    Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).

    Not yet reported Yale University 96 participants Est. completion 2014-10 1 site Stand-alone
    Alcohol use disorder Other conditions: Stress Disorders, Post-Traumatic
    View official trial listing →
  • Completed NCT NCT00753064

    AScVS and/ or Prazosin for Scorpion Envenomation

    Not yet reported Haffkine Bio-Pharmaceutical Corporation Ltd. 81 participants Est. completion 2007-12 5 sites
    Other conditions: Scorpion Envenomation
    View official trial listing →
  • Completed NCT NCT00762710

    Study of the Medication Prazosin for Alcohol Dependence

    Not yet reported Seattle Institute for Biomedical and Clinical Research 92 participants Est. completion 2014-06 1 site Stand-alone
    Other conditions: Alcoholism
    View official trial listing →
  • Completed NCT NCT00880997

    The Efficacy of Doxazosin for Cocaine Users

    Not yet reported Baylor College of Medicine 35 participants Est. completion 2011-12 1 site
    Other conditions: Cocaine Dependence
    View official trial listing →
  • Withdrawn NCT NCT00890643

    Effect of Prazosin on Neurophysiology and Cognition in Post-Traumatic Stress Disorder (PTSD)

    Not yet reported US Department of Veterans Affairs Est. completion 2011-09 1 site Stand-alone
    Other conditions: Posttraumatic Stress Disorder
    View official trial listing →
  • Completed NCT NCT00922506

    Combination Treatment With Doxazosin Plus TolterodineSR 2 mg Versus 4mg in Men With an Overactive Bladder (OAB) and Benign Prostatic Hyperplasia (BPH)

    Not yet reported Samsung Medical Center 83 participants Est. completion 2014-06 1 site
    Other conditions: Overactive Bladder, Benign Prostatic Hyperplasia
    View official trial listing →
  • Completed NCT NCT00990106

    Augmentation Trial of Prazosin for Post-Traumatic Stress Disorder (PTSD)

    Not yet reported Seattle Institute for Biomedical and Clinical Research 67 participants Est. completion 2013-03 2 sites
    Other conditions: Stress Disorders, Post-Traumatic, Combat Disorders, Sleep Disorders
    View official trial listing →
  • Completed NCT NCT01030874

    Orthostatic Hypotension Treatment on Rehab Unit

    Not yet reported VA Office of Research and Development 356 participants Est. completion 2016-05 1 site Stand-alone
    Other conditions: Orthostatic Hypotension, Falls
    View official trial listing →
  • Completed NCT NCT01062945

    The Effects of Doxazosin on the Cardiovascular and Subjective Effects of Cocaine

    Not yet reported Baylor College of Medicine 13 participants Est. completion 2011-01 1 site
    Other conditions: Cocaine Addiction, Cocaine Abuse, Cocaine Dependence, Substance Abuse
    View official trial listing →
  • Completed NCT NCT01100021

    Hemodynamic Study of Avanafil and Two α-Adrenergic Blockers,Doxazosin and Tamsulosin

    Not yet reported VIVUS LLC 48 participants Est. completion 2010-04 1 site
    Other conditions: Erectile Dysfunction
    View official trial listing →
  • Completed NCT NCT01126099

    Prazosin Treatment for Disruptive Agitation in Alzheimer's Disease

    Not yet reported Seattle Institute for Biomedical and Clinical Research 20 participants Est. completion 2014-03 1 site Stand-alone
    Other conditions: Alzheimer's Disease
    View official trial listing →
  • Completed NCT NCT01145183

    Pharmacogenetics of Doxazosin for Cocaine Dependence

    Not yet reported Baylor College of Medicine 96 participants Est. completion 2015-09 1 site
    Other conditions: Cocaine Dependence
    View official trial listing →
  • Completed NCT NCT01178138

    Monoamine Antagonist Therapies for Methamphetamine Abuse Prazosin

    Not yet reported University of Arkansas 24 participants Est. completion 2013-06 1 site
    Other conditions: Continuous Methamphetamine Abuse
    View official trial listing →
  • Completed NCT NCT01323998

    Benign Prostatic Hypertrophy Treatment Patterns & Outcomes: Marketscan

    GlaxoSmithKline 35032 participants Est. completion 2010-06
    Other conditions: Prostatic Hyperplasia
    View official trial listing →
  • Completed NCT NCT01332487

    Evaluating the Impact of Early Versus Delayed 5 Alpha Reductase Inhibitor Treatment on the Risk of Emergent Surgery in Men With Benign Prostatic Hyperplasia

    GlaxoSmithKline 4068 participants Est. completion 2010-08
    Other conditions: Prostatic Hyperplasia
    View official trial listing →
  • Completed NCT NCT01379898

    Phenoxybenzamine Versus Doxazosin in PCC Patients

    Not yet reported University Medical Center Groningen 134 participants Est. completion 2018-01 1 site
    Other conditions: Pheochromocytoma
    View official trial listing →
  • Completed NCT NCT01386177

    Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA)

    Not yet reported University Hospital, Basel, Switzerland 16 participants Est. completion 2012-01 1 site
    Substance use disorder Other conditions: Mood Disorder, Amphetamine-Related Disorders
    View official trial listing →
  • Completed NCT NCT01389609

    Bioequivalence Study of Doxazosin 4 Mg Orally-Disintegrating Tablet With Or Without Water To Doxazosin 4 Mg Japanese Marketed Immediate Release Tablet Under Fasted Condition

    Not yet reported Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 24 participants Est. completion 2011-08 1 site
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT01437046

    Doxazosin an a1 Antagonist for Alcohol Dependence

    Not yet reported Brown University 41 participants Est. completion 2015-03-01 2 sites
    Alcohol use disorder Other conditions: Anxiety
    View official trial listing →
  • Completed NCT NCT01518972

    Prazosin for Alcohol Dependence and Posttraumatic Stress Disorder

    Not yet reported Seattle Institute for Biomedical and Clinical Research 30 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Alcohol Abuse, Posttraumatic Stress Disorder
    View official trial listing →
  • Terminated NCT NCT01542372

    Two Stepped Care Models for Posttraumatic Stress Disorder (PTSD) Among Cambodian Refugees With PTSD

    Not yet reported Massachusetts General Hospital 114 participants Est. completion 2014-03 1 site
    Other conditions: Posttraumatic Stress Disorder (PTSD)
    View official trial listing →
  • Withdrawn NCT NCT01621165

    Prazosin as an Antimanic Agent in Severe Mania or Mixed States

    Not yet reported Mclean Hospital Est. completion 2009-11
    Other conditions: Bipolar, Mania, Bipolar, Mixed State
    View official trial listing →
  • Completed NCT NCT01637584

    Neurobiology of Sleep and Sleep Treatment Response in Returning Veterans

    Not yet reported University of Pittsburgh 40 participants Est. completion 2012-11 1 site Stand-alone
    Other conditions: Non PTSD, PTSD
    View official trial listing →
  • Terminated NCT NCT01642433

    Prazosin for Smoking Cessation

    Not yet reported Centre for Addiction and Mental Health 1 participants Est. completion 2013-09 1 site
    Other conditions: Nicotine Dependence
    View official trial listing →
  • Completed NCT NCT01661621

    Antimuscarinics as the First-line Treatment for Male With IPSS-V/S≤1

    Not yet reported Buddhist Tzu Chi General Hospital 395 participants Est. completion 2013-08 1 site
    Other conditions: Bladder Outlet Obstruction
    View official trial listing →
  • Completed NCT NCT01678313

    Cyclooxygenase-2 (COX-2) Inhibitor Reduces Serum Prostatic Specific Antigen (PSA) Levels

    Not yet reported Buddhist Tzu Chi General Hospital 140 participants Est. completion 2013-08 1 site
    Other conditions: Benign Prostatic Hyperplasia
    View official trial listing →
  • Completed NCT NCT01730846

    Does Doxazosin Attenuate Stress-induced Smoking and Improve Clinical Outcomes?

    Not yet reported Yale University 35 participants Est. completion 2016-11 1 site
    Other conditions: Smoking
    View official trial listing →
  • Completed NCT NCT01783704

    Improving Community Ambulation After Hip Fracture

    Not yet reported University of Maryland, Baltimore 210 participants Est. completion 2017-10-17 4 sites Stand-alone
    Other conditions: Hip Fracture
    View official trial listing →
  • Completed NCT NCT01798992

    Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart

    Not yet reported University of Colorado, Denver 56 participants Est. completion 2009-03 2 sites
    Other conditions: Idiopathic Dilated Cardiomyopathy
    View official trial listing →
  • Completed NCT NCT01862497

    Mechanisms of Increased Ambulatory Blood Pressure in Patients With Intradialytic Hypertension

    University of Texas Southwestern Medical Center 76 participants Est. completion 2018-04 1 site
    Other conditions: Intradialytic Hypertension
    View official trial listing →
  • Completed NCT NCT01916941

    Neural Mechanisms of Change During the Treatment of Alcohol Use Disorders With Prazosin

    Not yet reported University of New Mexico 36 participants Est. completion 2017-09 1 site
    Alcohol use disorder
    View official trial listing →
  • Completed NCT NCT01923129

    Optimal Duration of Indwelling Urinary Catheter Following Pelvic Surgery

    Not yet reported Cedars-Sinai Medical Center 142 participants Est. completion 2017-11-22 1 site Stand-alone
    Other conditions: Urinary Retention
    View official trial listing →
  • Completed NCT NCT01953432

    Pharmacogenetic Trial of Doxazosin for Treatment of Cocaine Abuse

    Not yet reported VA Office of Research and Development 43 participants Est. completion 2017-10-01 1 site
    Other conditions: Cocaine Dependence
    View official trial listing →
  • Completed NCT NCT01959022

    A Pilot Study to Assess the Effects of Doxazosin on Polysomnography in PTSD

    Not yet reported San Francisco Veterans Affairs Medical Center 15 participants Est. completion 2016-06 1 site
    Other conditions: Stress Disorders, Post-Traumatic
    View official trial listing →
  • Completed NCT NCT01999530

    The Effects of Prazosin on Dopamine in Healthy Humans: A PET Pilot Study

    Not yet reported Centre for Addiction and Mental Health 20 participants Est. completion 2016-08 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02193256

    Varenicline + Prazosin for Heavy Drinking Smokers

    Not yet reported Yale University 5 participants Est. completion 2015-06 1 site
    Alcohol use disorder Other conditions: Cigarette Smoking
    View official trial listing →
  • Completed NCT NCT02199652

    Reducing Suicidal Ideation Through Treatment of Nightmares-Post Traumatic Stress Disorder (PTSD)

    Not yet reported Augusta University 20 participants Est. completion 2017-12-01 1 site Stand-alone
    Other conditions: Post Traumatic Stress Disorder, Suicidal Ideation, Nightmares
    View official trial listing →
  • Completed NCT NCT02226367

    Prazosin Augmentation of Outpatient Treatment of Alcohol Use Disorders in Active Duty Soldiers With and Without PTSD

    Not yet reported Seattle Institute for Biomedical and Clinical Research 158 participants Est. completion 2018-10-20 1 site
    Alcohol use disorder Other conditions: Stress Disorders, Posttraumatic, Combat Disorders
    View official trial listing →
  • Completed NCT NCT02266329

    Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

    Not yet reported, Not yet reported VA Office of Research and Development 89 participants Est. completion 2023-09-30 1 site
    Other conditions: Posttraumatic Headache, Combat Disorders, Post Concussion Syndrome, Headache, Mild Traumatic Brain Injury, Posttraumatic Migraine
    View official trial listing →
  • Completed NCT NCT02266537

    Study to Assess the Influence of Three Different α-antagonists and Placebo on the Extent of Weekly Phenylephrine-induced Mydriasis at Three Different Concentrations of Phenylephrine in Healthy Male Volunteers

    Not yet reported Boehringer Ingelheim 97 participants
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02308202

    DOXAZOSIN FOR PTSD

    Not yet reported Baylor College of Medicine 30 participants Est. completion 2014-06-30 1 site
    Other conditions: PTSD
    View official trial listing →
  • Completed NCT NCT02322047

    Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders

    Not yet reported Seattle Institute for Biomedical and Clinical Research 31 participants Est. completion 2018-10-10 1 site Stand-alone
    Alcohol use disorder Other conditions: Posttraumatic Stress Disorder (PTSD)
    View official trial listing →
  • Completed NCT NCT02364089

    Surgery of Subclinical Cortisol Secreting Adrenal Incidentalomas

    Not yet reported University Hospital, Bordeaux 78 participants Est. completion 2022-11-23 17 sites
    Other conditions: Adrenal Incidentalomas
    View official trial listing →
  • Status unknown NCT NCT02369081

    Optimum Treatment for Drug-Resistant Hypertension

    Not yet reported University of Cambridge 348 participants Est. completion 2015-08 16 sites
    Other conditions: Hypertension, Resistant to Conventional Therapy
    View official trial listing →
  • Completed NCT NCT02382848

    Effectiveness of Prazosin in Bulimic Patients Experiencing Nightmares Due to PTSD

    Not yet reported Milton S. Hershey Medical Center 9 participants Est. completion 2018-03-09 1 site
    Obstructive sleep apnea Other conditions: Stress Disorders, Post-Traumatic
    View official trial listing →
  • Withdrawn NCT NCT02384369

    Trial of Oral SNC-102 in Subjects With Combat-Related Posttraumatic Stress Disorder

    Not yet reported Synchroneuron Inc. Est. completion 2017-08
    Other conditions: Post-Traumatic Stress Disorders, Posttraumatic Stress Disorders, Stress Disorders, Post-Traumatic, Post-Traumatic Stress Disorders, Combat-related
    View official trial listing →
  • Completed NCT NCT02431936

    Effectiveness of Prazosin on the Urinary Sodium Excretion Response to Mental Stress

    Not yet reported Augusta University 50 participants Est. completion 2019-04-16 1 site Stand-alone
    Other conditions: Hypertension, Stress, Psychological, Blood Pressure
    View official trial listing →
  • Completed NCT NCT02500602

    CAP: Doxazosin in the Treatment of Co-Occurring PTSD and Alcohol Use Disorders

    Not yet reported VA Office of Research and Development 144 participants Est. completion 2019-12-16 1 site
    Alcohol use disorder Other conditions: Posttraumatic Stress Disorder
    View official trial listing →
  • Completed NCT NCT02538744

    Complementary Combination Therapy for Cocaine Dependence

    Not yet reported Baylor College of Medicine 45 participants Est. completion 2018-08-21 1 site
    Other conditions: Cocaine Dependence
    View official trial listing →
  • Terminated NCT NCT02539810

    Renal Artery Stenting in Patients With Documented Resistant Hypertension and Atherosclerotic Renal Artery Stenosis (ANDORRA)

    Not yet reported Assistance Publique - Hôpitaux de Paris 4 participants Est. completion 2017-07 15 sites Stand-alone
    Other conditions: Hypertension, Hypertension Resistant to Conventional Therapy, Angiographically Proven Grade III Unilateral or Bilateral Atherosclerotic Renal Artery Stenosis (ARAS) Greater Than or Equal to 60 Percent
    View official trial listing →
  • Status unknown NCT NCT02563405

    The Effects of Doxazosin and Nifedipine on Blood Pressure Variability and Uric Acid in Plasma in Hypertensive Patients

    Not yet reported, Not yet reported First Affiliated Hospital of Harbin Medical University 30 participants Est. completion 2018-10 1 site
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT02616094

    Multimodal Neuroimaging of Stress and Reward Cues to Assess Alcoholism Risk and Relapse

    Not yet reported Yale University 224 participants Est. completion 2022-06-30 1 site
    Alcohol use disorder
    View official trial listing →
  • Completed NCT NCT02655354

    A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity

    Not yet reported University of Washington 635 participants Est. completion 2019-11 24 sites Stand-alone
    Substance use disorder Other conditions: Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation, Mild Cognitive Impairment, Quality of Life, Pain, Wounds and Injury, Brain Injuries, Chronic Disease
    View official trial listing →
  • Completed NCT NCT02785393

    DOX as a Potential Treatment for Methamphetamine Dependence

    Not yet reported Baylor College of Medicine 11 participants Est. completion 2016-03 1 site
    Substance use disorder
    View official trial listing →
  • Completed NCT NCT02901977

    Doxazosin and Ramipril in Hypertension

    Not yet reported Karolinska Institutet 71 participants Est. completion 2015-04 1 site
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT02965027

    Prazosin for Post-Concussive Headaches

    Not yet reported Seattle Institute for Biomedical and Clinical Research 89 participants Est. completion 2023-06-07 2 sites Stand-alone
    Other conditions: Post-Traumatic Headache
    View official trial listing →
  • Completed NCT NCT02966340

    Repurposing alpha1 Noradrenergic Antagonists for Alcoholism Treatment

    Not yet reported, Not yet reported University of Wisconsin, Madison 70 participants Est. completion 2018-03-12 1 site Stand-alone
    Other conditions: Alcoholism
    View official trial listing →
  • Completed NCT NCT02989493

    Testing Doxazosin to Treat Stress Mechanisms in Alcoholism

    Not yet reported University of Wisconsin, Madison 61 participants Est. completion 2020-03-13 1 site
    Other conditions: Alcoholism
    View official trial listing →
  • Withdrawn NCT NCT03010995

    The Acute Cardiovascular Effects of Nicotine in E-cigarettes (ACE) Study

    Not yet reported University of Louisville Est. completion 2018-07-24 1 site
    Cardiovascular disease Other conditions: Cigarette Smoking Toxicity, Nicotine
    View official trial listing →
  • Completed NCT NCT03045016

    Efficacy of Prazosin in Preventing Post-traumatic Stress Disorder

    Not yet reported Hospices Civils de Lyon 15 participants Est. completion 2020-03-30 1 site Stand-alone
    Other conditions: Acute Stress Disorder
    View official trial listing →
  • Completed NCT NCT03176693

    Preoperative Alpha Blockade for Pheochromocytoma

    Not yet reported University of California, Los Angeles 39 participants Est. completion 2021-10-10 1 site
    Other conditions: Pheochromocytoma, Paraganglioma
    View official trial listing →
  • Terminated NCT NCT03221751

    Prazosin and Cerebrospinal Fluid (CSF) Biomarkers in Mild Traumatic Brain Injury (mTBI)

    Not yet reported VA Office of Research and Development 9 participants Est. completion 2023-12-05 1 site Stand-alone
    Other conditions: Dementia
    View official trial listing →
  • Status unknown NCT NCT03339258

    A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD

    Not yet reported San Francisco Veterans Affairs Medical Center 80 participants Est. completion 2024-06 1 site Stand-alone
    Other conditions: Stress Disorders, Post-Traumatic
    View official trial listing →
  • Withdrawn NCT NCT03398252

    Targeting Stress-Induced Alcohol Relapse Risk With Doxazosin XL

    Not yet reported The University of Texas Health Science Center, Houston Est. completion 2023-10-01
    Alcohol use disorder
    View official trial listing →
  • Terminated NCT NCT03410823

    PUSH Plus Protein Pilot for Hip Fracture Patients

    Not yet reported University of Maryland, Baltimore 20 participants Est. completion 2020-12-12 2 sites Stand-alone
    Other conditions: Hip Fracture
    View official trial listing →
  • Withdrawn NCT NCT03416569

    Effects of Prazosin on the Attention-Enhancing Effects of Nicotine

    Not yet reported University of Maryland, Baltimore Est. completion 2019-01 Stand-alone
    Other conditions: no Condition, Basic Science
    View official trial listing →
  • Active, not recruiting NCT NCT03539614

    Predicting Responses to PTSD Treatment With Iris and Cardiovascular Tests

    Not yet reported VA Office of Research and Development 87 participants Est. completion 2026-12-31 1 site Stand-alone
    Other conditions: Posttraumatic Stress Disorder
    View official trial listing →
  • Completed NCT NCT03710642

    Prazosin for Agitation in Alzheimer's Disease

    Not yet reported Alzheimer's Disease Cooperative Study (ADCS) 35 participants Est. completion 2022-01-05 14 sites
    Other conditions: Alzheimer's Disease, Disruptive Behavior
    View official trial listing →
  • Suspended NCT NCT03894345

    Prazosin Use in Adults With Anxiety Disorders

    Not yet reported University of Manitoba 20 participants Est. completion 2023-12 1 site Stand-alone
    Other conditions: Anxiety, Anxiety Disorders
    View official trial listing →
  • Withdrawn NCT NCT03997864

    Administration of Prazosin to Prevent PTSD in Adult Women After Sexual Assault

    Not yet reported University of Colorado, Denver Est. completion 2021-08-20 1 site
    Other conditions: Posttraumatic Stress Disorder
    View official trial listing →
  • Completed NCT NCT04108104

    Clinical Outcome of a Patented Pharmaceutical Composition (KT-110) to Treat Alcohol Use Disorder While Avoiding Major Side Effects

    Not yet reported Kinnov Therapeutics 154 participants Est. completion 2022-01-31 35 sites
    Alcohol use disorder
    View official trial listing →
  • Active, not recruiting NCT NCT04135846

    Alpha-1 Blockade for Alcohol Use Disorder (AUD)

    Not yet reported Brown University 184 participants Est. completion 2026-12-31 1 site
    Alcohol use disorder
    View official trial listing →
  • Completed NCT NCT04280965

    Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury

    Not yet reported The University of Texas Health Science Center at San Antonio 28 participants Est. completion 2022-10-17 1 site
    Other conditions: Post Traumatic Stress Disorder
    View official trial listing →
  • Completed NCT NCT04320589

    the Effect of Dexmedetomidine and Magnesium Sulfate in Open Resection of Pheochromocytoma

    Not yet reported National Cancer Institute, Egypt 30 participants Est. completion 2021-08-30 1 site
    Other conditions: Pheochromocytoma
    View official trial listing →
  • Terminated NCT NCT04365257

    Prazosin to Prevent COVID-19 (PREVENT-COVID Trial)

    Not yet reported Johns Hopkins University 5 participants Est. completion 2022-03-31 1 site Stand-alone
    Other conditions: COVID-19
    View official trial listing →
  • Status unknown NCT NCT04371757

    Influence of the Autonomic Nervous System in Response to Exercise in Hypertensive Individuals

    Not yet reported Instituto de Cardiologia do Rio Grande do Sul 39 participants Est. completion 2021-12-23 1 site
    Other conditions: Autonomic Nervous System, Hypertension
    View official trial listing →
  • Completed NCT NCT04467931

    ACEI or ARB and COVID-19 Severity and Mortality in US Veterans

    University of Utah 22213 participants Est. completion 2020-12-31 1 site
    Other conditions: Hypertension, COVID
    View official trial listing →
  • Completed NCT NCT04557072

    Selective Versus Nonselective Alpha-blockade Prior to Pheochromocytoma Resection - Systematic Review and Meta-analysis

    Jagiellonian University 1344 participants Est. completion 2020-11-02 1 site
    Other conditions: Pheochromocytoma
    View official trial listing →
  • Completed NCT NCT04721353

    Reducing Cannabis Overuse With Prazosin

    Not yet reported VA Puget Sound Health Care System 11 participants Est. completion 2025-06-01 1 site Stand-alone
    Other conditions: Cannabis Dependence, Posttraumatic Stress Disorder, Cannabis Use Disorder
    View official trial listing →
  • Completed NCT NCT04793685

    Prazosin for Alcohol Use Disorder With Withdrawal Symptoms

    Not yet reported Yale University 152 participants Est. completion 2026-06-30 1 site Stand-alone
    Other conditions: Alcohol Withdrawal
    View official trial listing →
  • Completed NCT NCT04967443

    Pivotal Bioequivalence Study to Qualify Manufacturing Site Transfer for Prazosin Hydrochloride Capsules

    Not yet reported Pfizer 72 participants Est. completion 2022-02-15 1 site Stand-alone
    Heart failure Other conditions: Hypertension
    View official trial listing →
  • Terminated NCT NCT05189977

    A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline

    Not yet reported Otsuka Pharmaceutical Development & Commercialization, Inc. 34 participants Est. completion 2023-08-03 1 site
    Other conditions: Post-traumatic Stress Disorder (PTSD)
    View official trial listing →
  • Suspended NCT NCT05360953

    Treating Nightmares in Posttraumatic Stress Disorder With Clonidine and Doxazosin

    Not yet reported Charite University, Berlin, Germany 53 participants Est. completion 2026-07-31 5 sites
    Other conditions: Posttraumatic Stress Disorder
    View official trial listing →
  • Completed NCT NCT06147622

    A Study to Assess the Pharmacokinetic Profile of Prazosin and Cyproheptadine

    Not yet reported Kinnov Therapeutics 12 participants Est. completion 2024-12-31 1 site Stand-alone
    Alcohol use disorder
    View official trial listing →
  • Completed NCT NCT06282731

    The Changes of Urine Growth Factors Level

    Not yet reported En Chu Kong Hospital 74 participants Est. completion 2017-04-27 1 site
    Other conditions: Benign Prostatic Hyperplasia
    View official trial listing →
  • Status unknown NCT NCT06287905

    A Comparative Study of Using Scorpion Antivenom Versus Scorpion Antivenom and Prazosin

    Not yet reported Sohag University 80 participants Est. completion 2024-07-01 1 site Stand-alone
    Other conditions: Morality
    View official trial listing →
  • Not yet recruiting NCT NCT06615440

    Management and Outcome of Scorpion Sting in Children

    Assiut University 70 participants Est. completion 2026-10 1 site
    Other conditions: Scorpion Stings
    View official trial listing →
  • Completed NCT NCT07231978

    A Study to Learn How Different Forms of the Study Medicine Called Prazosin Are Taken up Into the Blood in Healthy Adults

    Not yet reported Pfizer 69 participants Est. completion 2026-04-30 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Not yet recruiting NCT NCT07862712

    Assessing Trauma-related Links Between Affective and Metabolic Systems

    Not yet reported VA Office of Research and Development 70 participants Est. completion 2032-12-31 1 site Stand-alone
    Metabolic syndrome Other conditions: Posttraumatic Stress Disorder, Insulin Resistance
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: Prazosin Hydrochloride, Prazosin HCL, prazosin, Minipress

Related On The Pen coverage

No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.