About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Oyster Shell Calcium Carbonate, Crude
- Company
- Duquesne University
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 89 recruiting
Efficacy results: Not yet reported
89 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Nov 12, 2026
Find a Clinical Trial Near Me
See recruiting studies for Oyster Shell Calcium Carbonate, Crude and check eligibility with the study team.
Trial details
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Recruiting NCT NCT02621944
Melatonin as a Neuroprotective Therapy in Neonates With HIE Undergoing Hypothermia
Not yet reported University of Florida 70 participants Est. completion 2027-03 2 sites Stand-aloneOther conditions: Hypoxic Ischemic EncephalopathyView official trial listing → -
Recruiting NCT NCT03438526
The Basel BOMP-AID Randomized Trial
Not yet reported University Hospital, Basel, Switzerland 190 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Hypoactive DeliriumView official trial listing → -
Recruiting NCT NCT03954899
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging
Not yet reported Natalie Denburg 230 participants Est. completion 2028-02 1 site Stand-aloneOther conditions: Mild Cognitive Impairment, Cognitive Decline, Healthy AgingView official trial listing → -
Recruiting NCT NCT04400266
Buspirone and Melatonin for Depression Following Traumatic Brain Injury
Not yet reported Massachusetts General Hospital 10 participants Est. completion 2028-07-31 2 sites Stand-aloneOther conditions: Depression, Brain Injuries, TraumaticView official trial listing → -
Recruiting NCT NCT04521972
Impact of Room Light on Uterine Contractions and Labor Progression in Pregnancy
Not yet reported Michigan State University 100 participants Est. completion 2029-09-01 1 site Stand-aloneOther conditions: Pregnancy Related, Labor; Poor, Uterine Contractions WeakView official trial listing → -
Recruiting NCT NCT04547439
Sleep, Diabetic Retinopathy and Melatonin
Not yet reported University of Illinois Chicago 42 participants Est. completion 2026-06 1 siteOther conditions: Diabetes Mellitus, Diabetic RetinopathyView official trial listing → -
Recruiting NCT NCT04580134
CLOZAPINE Response in Biotype-1
Not yet reported University of Texas Southwestern Medical Center 524 participants Est. completion 2027-04-30 5 sites Stand-aloneOther conditions: Schizophrenia, Schizoaffective Disorder, Bipolar 1 DisorderView official trial listing → -
Recruiting NCT NCT04588233
Melatonin Adolescent Research Study
Not yet reported Loma Linda University 80 participants Est. completion 2027-05 2 sites Stand-aloneOther conditions: Sleep Disorders in ChildrenView official trial listing → -
Recruiting NCT NCT05084196
Melatonin for Prevention of Kidney Injury
Not yet reported Rutgers, The State University of New Jersey 300 participants Est. completion 2027-12-31 2 sites Stand-aloneOther conditions: Acute Kidney Injury, Adverse Drug EventView official trial listing → -
Recruiting NCT NCT05116904
Smith Magenis Syndrome and Autism Spectrum Disorders
Not yet reported Hospices Civils de Lyon 40 participants Est. completion 2027-04 2 sitesOther conditions: Smith-Magenis Syndrome, Autism Spectrum DisorderView official trial listing → -
Recruiting NCT NCT05184933
Sleep and Circadian Mechanisms in Hypertension
Not yet reported Oregon Health and Science University 32 participants Est. completion 2029-03-30 1 site Stand-aloneCardiovascular disease Other conditions: Hypertension, Cardiovascular Risk Factors, Circadian Rhythms, SleepView official trial listing → -
Recruiting NCT NCT05247125
The Role of Circadian Factors in Regulation of Neuroplasticity in Ischemic Stroke (Interventional)
Not yet reported Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health 80 participants Est. completion 2026-12-31 1 site Stand-aloneCardiovascular disease Other conditions: Sleep Disorders, Circadian RhythmView official trial listing → -
Recruiting NCT NCT05358834
Testing Effects of Melatonin on Uterine Contractions in Women
Not yet reported Brigham and Women's Hospital 120 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Pregnant WomenView official trial listing → -
Recruiting NCT NCT05502900
Adjuvant Melatonin for Uveal Melanoma
Not yet reported Gustav Stalhammar 100 participants Est. completion 2031-01-01 1 site Stand-aloneOther conditions: Uveal Melanoma, Uveal Melanoma, Posterior, Medium/Large Size, Eye Cancer, Intraocular MelanomaView official trial listing → -
Recruiting NCT NCT05541276
MELAtonin for Prevention of Postoperative Agitation and Emergence Delirium in Children
Not yet reported Arash Afshari 676 participants Est. completion 2027-04-01 1 site Stand-aloneOther conditions: Emergence DeliriumView official trial listing → -
Recruiting NCT NCT05617833
Safety of Erythropoietin and Melatonin for Very Preterm Infants With Intraventricular Hemorrhage
Not yet reported Johns Hopkins University 60 participants Est. completion 2027-09 2 sites Stand-aloneOther conditions: Intraventricular Hemorrhage of PrematurityView official trial listing → -
Recruiting NCT NCT05629871
Biomarkers of Sleep-wake Cycle in Prodromal Alzheimer's Disease: Role in Cognitive Decline?
Not yet reported University Hospital, Montpellier 132 participants Est. completion 2027-07-01 3 sites Stand-aloneOther conditions: NeuropathologyView official trial listing → -
Recruiting NCT NCT05651347
Antenatal Melatonin Supplementation for Neuroprotection in Fetal Growth Restriction
Not yet reported Monash University 336 participants Est. completion 2027-04-30 12 sitesOther conditions: Fetal Growth Retardation, Stillbirth and Fetal Death, Pregnancy PretermView official trial listing → -
Recruiting NCT NCT05701969
Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift
Not yet reported University of Virginia 50 participants Est. completion 2028-06-30 1 site Stand-aloneOther conditions: Sleep Disorders, Circadian RhythmView official trial listing → -
Recruiting NCT NCT05713877
Melatonin for Treatment of Delirium in Critically Ill Adult Patients
Not yet reported Ciusss de L'Est de l'Île de Montréal 30 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: DeliriumView official trial listing → -
Recruiting NCT NCT05829044
Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms
Not yet reported Massachusetts General Hospital 48 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Normal PhysiologyView official trial listing → -
Recruiting NCT NCT05878730
Melatonin and Response to Lithium
Assistance Publique - Hôpitaux de Paris 60 participants Est. completion 2026-12 1 siteOther conditions: Bipolar Disorder IView official trial listing → -
Recruiting NCT NCT05958940
BioClock: Bright Light Therapy for Depressive Disorders
Not yet reported Universiteit Leiden 231 participants Est. completion 2026-12 2 sitesOther conditions: Depression, Unipolar, Depression, BipolarView official trial listing → -
Recruiting NCT NCT06062953
Efficacy of Melatonin, Low-dose Quetiapine, or Placebo in Patients With Psychiatric Disorders and Comorbid Insomnia
Not yet reported, Not yet reported Lone Baandrup 255 participants Est. completion 2029-02-28 1 site Stand-aloneOther conditions: Psychiatric Disorders, InsomniaView official trial listing → -
Recruiting NCT NCT06093477
Studying Melatonin and Recovery in Teens
Not yet reported Stanford University 45 participants Est. completion 2027-10-31 1 site Stand-aloneOther conditions: Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital, Kyphosis, Spondylolisthesis, Pectus Surgery, Hip SurgeryView official trial listing → -
Recruiting NCT NCT06104280
Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment
University of Alabama at Birmingham 200 participants Est. completion 2029-01-01 1 siteSubstance use disorder Other conditions: Sleep DisturbanceView official trial listing → -
Recruiting NCT NCT06194162
Weighted Blankets for Sleep Disturbance Among Children With ADHD
Not yet reported University Hospital Bispebjerg and Frederiksberg 340 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Attention-deficit Hyperactivity, Attention Deficit Hyperactivity Disorder, Neurodevelopmental Disorders, Sleep Disturbance, Attention Deficit Disorder, Hyperkinetic Conduct Disorder, Attention-Deficit Hyperactivity Disorder, Unspecified TypeView official trial listing → -
Recruiting NCT NCT06226025
Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder
Not yet reported Leslie Swanson 50 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Bipolar Disorder, Delayed Sleep-Wake Phase DisorderView official trial listing → -
Recruiting NCT NCT06236932
Susceptibility to Infectious Diseases in obEsity: an endocRine trAnslational socioLogic Evaluation, "SIDERALE"
Not yet reported Federico II University 100 participants Est. completion 2026-10-29 4 sitesOther conditions: Obesity, Type2diabetes, Lipodystrophy, Infections, Obesity Associated DisorderView official trial listing → -
Recruiting NCT NCT06245434
Circadian Rhythmicity During Coma Awakening
Not yet reported Hospices Civils de Lyon 90 participants Est. completion 2029-06-02 1 site Stand-aloneOther conditions: Acute Brain Injury ComaView official trial listing → -
Recruiting NCT NCT06252571
a Chronobiological Treatment Combining Evening Melatonin and Morning Light Therapy in Idiopathic Hypersomnia: a Prospective, Double Bind, Randomized, Placebo-controlled -Trial
Not yet reported University Hospital, Strasbourg, France 72 participants Est. completion 2027-09-07 1 site Stand-aloneOther conditions: Idiopathic HypersomniaView official trial listing → -
Recruiting NCT NCT06380491
Melatonin's Effect on Nighttime Blood Pressure and Sleep in OSA Patients (MEBP-OSA)
Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 50 participants Est. completion 2028-01-22 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Recruiting NCT NCT06422741
Effect of a Grape Seed Proanthocyanidin Extract (GSPE) on LDL Cholesterol Levels in Rotating Night Shift Workers
Not yet reported Fundació Eurecat 22 participants Est. completion 2026-02 2 sitesCardiovascular disease Other conditions: Circadian Rhythm Sleep Disorder, Shift Work Type, Cholesterol Level, HighView official trial listing → -
Recruiting NCT NCT06430086
Mechanistic Effect of Walnut Consumption on Sleep Quality
Not yet reported Columbia University 24 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Poor Sleep QualityView official trial listing → -
Recruiting NCT NCT06430333
Sleep to Reduce Incident Depression Effectively in Peripartum
Not yet reported Henry Ford Health System 500 participants Est. completion 2028-02-29 1 siteOther conditions: Insomnia, DepressionView official trial listing → -
Recruiting NCT NCT06487533
Sensing Physiological Symptoms of Opioid Withdrawal and Cravings in Patients With Opioid Use Disorder
Spark Biomedical, Inc. 20 participants Est. completion 2027-05-31 2 sitesSubstance use disorder Other conditions: Opioid WithdrawalView official trial listing → -
Recruiting NCT NCT06489327
Comparing Two Doses of Oral Melatonin as Premedication in Children Undergoing Surgery
Not yet reported Al-Azhar University 120 participants Est. completion 2026-12-15 2 sitesOther conditions: Preoperative AnxietyView official trial listing → -
Recruiting NCT NCT06502613
Idiopathic Scoliosis New Onset and Melatonin Phase Delay in Children
Second Affiliated Hospital of Wenzhou Medical University 956 participants Est. completion 2027-07-15 1 siteOther conditions: Scoliosis Idiopathic, Circadian Rhythm, MelatoninView official trial listing → -
Recruiting NCT NCT06505447
PICU-related Sleep and Circadian Dysregulation Pilot Study
Not yet reported State University of New York at Buffalo 30 participants Est. completion 2027-01-01 1 site Stand-aloneOther conditions: Circadian Dysrhythmia, Sleep Disturbance, Critical Illness, Children, OnlyView official trial listing → -
Recruiting NCT NCT06509191
The Use of Melatonin for Delirium Prevention in Medically Hospitalized Patients
Not yet reported, Not yet reported Sultan Qaboos University 240 participants Est. completion 2025-06 2 sites Stand-aloneOther conditions: DeliriumView official trial listing → -
Recruiting NCT NCT06544018
Circadian Rhythm Deregulation in Patients With CAPS
Not yet reported Hospices Civils de Lyon 30 participants Est. completion 2029-02-25 6 sitesOther conditions: Cryopyrin Associated Periodic Syndrome, Familial Cold Urticaria, Muckle-Wells Syndrome, CINCA SyndromeView official trial listing → -
Recruiting NCT NCT06627504
Type 1 Diabetes REst for Metabolic Health
Not yet reported University of Colorado, Denver 50 participants Est. completion 2029-08-31 1 site Stand-aloneOther conditions: Type 1 Diabetes (T1D), Sleep HealthView official trial listing → -
Recruiting NCT NCT06669507
The Sleep Clinic Outcome and Practice Study
Not yet reported St. Olavs Hospital 3400 participants Est. completion 2030-12-31 1 siteOther conditions: Insomnia Disorder, Circadian Rhythm Sleep DisorderView official trial listing → -
Recruiting NCT NCT06678880
Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction
Not yet reported University of California, San Diego 120 participants Est. completion 2029-02-28 1 siteOther conditions: Depression, Depression During the Menopausal Transition, Menopausal DepressionView official trial listing → -
Recruiting NCT NCT06694441
Noradrenergic Dysregulation, Sleep and Cognition in Older Adults With Insomnia
Not yet reported Northwestern University 60 participants Est. completion 2029-08-31 1 site Stand-aloneOther conditions: InsomniaView official trial listing → -
Recruiting NCT NCT06768580
Effect of Oral Melatonin Versus Intraoperative Lidocaine Infusion on Incidence of Postoperative Delirium in Elderly Patients Undergoing Total Hip Arthroplasty
Not yet reported Tanta University 135 participants Est. completion 2026-10-01 1 site Stand-aloneOther conditions: Oral Melatonin, Lidocaine Infusion, Postoperative Delirium, Elderly Patients, Total Hip ArthroplastyView official trial listing → -
Recruiting NCT NCT06768749
The Impact of Melatonin Lotion on Sleep and Mental Health
Not yet reported University of Redlands 60 participants Est. completion 2028-04-01 1 site Stand-aloneOther conditions: Sleep Problems, Depressive Disorder and Anxiety DisordersView official trial listing → -
Recruiting NCT NCT06802913
A Novel Inhaled Formulation of Melatonin to Treat Adults With Insomnia: Efficacy Study
Not yet reported Woolcock Institute of Medical Research 10 participants Est. completion 2026-05 1 site Stand-aloneOther conditions: InsomniaView official trial listing → -
Recruiting NCT NCT06808425
Intervention With Weighted Blankets for Children With ADHD and Sleep Problems: Implementation and Effectiveness
Not yet reported Halmstad University 200 participants Est. completion 2034-02 1 siteOther conditions: ADHD, Sleep Disturbances, Sleep, Sleep ProblemsView official trial listing → -
Recruiting NCT NCT06826755
Melatonin Effects on Cardiovascular Disease Mechanisms in Midlife Women: A Randomized Clinical Trial
Not yet reported Mayo Clinic 70 participants Est. completion 2028-01 1 siteOther conditions: Perimenopause, HypertensionView official trial listing → -
Recruiting NCT NCT06846086
Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy
Not yet reported Tanta University 46 participants Est. completion 2026-02-01 1 site Stand-aloneOther conditions: CardiomyopathiesView official trial listing → -
Recruiting NCT NCT06949904
The Role of Melatonin as an Adjuvant Therapy in Childhood Pneumonia
Not yet reported, Not yet reported Mian Muhammad Hassan Ahmed 60 participants Est. completion 2026-01 1 site Stand-aloneOther conditions: Pneumonia ChildhoodView official trial listing → -
Recruiting NCT NCT06971640
Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition
Duke University 250 participants Est. completion 2029-11 1 siteOther conditions: ADHD - Attention Deficit Disorder With Hyperactivity, ADHDView official trial listing → -
Recruiting NCT NCT06996171
Comparative Efficacy of Magnesium Supplement and Melatonin Congener in Young Adults With Primary Insomnia
Not yet reported CMH Kharian Medical College 60 participants Est. completion 2025-10-30 1 siteOther conditions: Primary InsomniaView official trial listing → -
Recruiting NCT NCT07036367
The Use of Sublingual Melatonin Premedication in Geriatric Cataract Surgery
Not yet reported Al-Azhar University 60 participants Est. completion 2026-06-15 2 sitesOther conditions: Cataract Surgery AnesthesiaView official trial listing → -
Recruiting NCT NCT07036796
Effect of Melatonin in Patients With Diabetic Peripheral Neuropathy
Not yet reported Ain Shams University 60 participants Est. completion 2027-07-04 1 siteOther conditions: Diabetic Peripheral Neuropathy, Diabetic Neuropathy, Diabetic Peripheral Neuropathy in Type 2 Diabetic PatientsView official trial listing → -
Recruiting NCT NCT07046429
Affect of Melatonin on Sleep and Cognition in Cirrhosis
Not yet reported Weill Medical College of Cornell University 18 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Hepatic Encephalopathy, Covert Hepatic Encephalopathy, Cirrhosis, Sleep Disturbances and InsomniaView official trial listing → -
Recruiting NCT NCT07119567
Impact of Cocaine Use and Withdrawal on Sleep
Hôpital le Vinatier 32 participants Est. completion 2028-12-31 3 sitesOther conditions: Cocaine Use DisorderView official trial listing → -
Recruiting NCT NCT07120880
Efficacy of Chronotherapeutic Combination for Major Depressive Episode With Insomnia
Not yet reported Assistance Publique - Hôpitaux de Paris 184 participants Est. completion 2029-01 1 siteOther conditions: Major Depressive Disorder (MDD) With InsomniaView official trial listing → -
Recruiting NCT NCT07167732
CTNNB1 Neurodevelopmental Syndrome - Natural History Study
University Medical Centre Ljubljana 250 participants Est. completion 2030-01 2 sitesOther conditions: CTNNB1 Neurodevelopmental SyndromeView official trial listing → -
Recruiting NCT NCT07294781
Circadian Rhythms and Time Perception in Healthy Adults During Constant Wakefulness
Not yet reported University of Aarhus 30 participants Est. completion 2027-12-30 1 siteOther conditions: Sleep Deprivation, Circadian Rhythm, Healthy Volunteers, Time PerceptionView official trial listing → -
Recruiting NCT NCT07307677
Melatonin & Metformin on Clinical & Biochemical Parameters in Insulin Resistant PCOS Compared to Metformin
Not yet reported Mst.Sumyara Khatun 60 participants Est. completion 2026-08-10 1 site Stand-aloneOther conditions: PCOS(Insulin Resistant)View official trial listing → -
Recruiting NCT NCT07315074
Effect of Esketamine on Postoperative Sleep in Postmenopausal Women
Not yet reported Zhuan Zhang 164 participants Est. completion 2026-12-31 2 sitesOther conditions: Circadian Rhythm, Postoperative Sleep DisturbanceView official trial listing → -
Recruiting NCT NCT07336277
Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients
Not yet reported Emory University 30 participants Est. completion 2027-07 1 site Stand-aloneOther conditions: Orthopedic Trauma, Sleep QualityView official trial listing → -
Recruiting NCT NCT07344467
Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine Surgery
Not yet reported Tanta University 105 participants Est. completion 2027-06-01 1 site Stand-aloneOther conditions: Oral, Melatonin, Pregabalin, Postoperative Pain, Anxiety, Spine SurgeryView official trial listing → -
Recruiting NCT NCT07345715
Oral Melatonin Versus Nebulized Dexmedetomidine on Emergence Agitation in Children Undergoing Adenotonsillectomy
Not yet reported Tanta University 96 participants Est. completion 2027-07-01 1 site Stand-aloneOther conditions: Oral Melatonin, Nebulized Dexmedetomidine, Emergence Agitation, Children, AdenotonsillectomyView official trial listing → -
Recruiting NCT NCT07375342
Melatonin for Post Tonsillectomy Emergence Agitation in Pediatric
Not yet reported Benha University 120 participants Est. completion 2026-08-01 1 siteOther conditions: Post Tonsillectomy Emergence AgitationView official trial listing → -
Recruiting NCT NCT07391852
Circadian Light Exposure Adjustment for Restfulness
Not yet reported University of Arizona 60 participants Est. completion 2030-03-31 1 site Stand-aloneOther conditions: Sleep Onset LatencyView official trial listing → -
Recruiting NCT NCT07401836
Standardized Sleep Bundle for Cardiac Surgery Patients
Not yet reported Horizon Health Network 20 participants Est. completion 2026-06 1 site Stand-aloneOther conditions: SleepView official trial listing → -
Recruiting NCT NCT07411404
Assessment and Characterization of Sleep Among Video Game Adult Players Without Video Game Use Disorder : a Feasability Study
Not yet reported Centre Hospitalier Universitaire de Besancon 40 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: Sleep, Video GamersView official trial listing → -
Recruiting NCT NCT07433491
Blue-blocking Glasses for Sleep Disorders in Child and Adolescent Psychiatry
Not yet reported Helse Fonna 40 participants Est. completion 2027-06-01 2 sitesOther conditions: Insomnia, Delayed Sleep Phase Disorder, Hyperarousal, Transdiagnostic Psychopathology, Child and Adolescent PsychiatryView official trial listing → -
Recruiting NCT NCT07472075
Melatonin Versus Placebo for Bipolar Disorder
Not yet reported Lars Vedel Kessing 200 participants Est. completion 2028-06 1 siteOther conditions: Bipolar Affective DisorderView official trial listing → -
Recruiting NCT NCT07542756
A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia
Not yet reported University of Pennsylvania 1200 participants Est. completion 2032-01-01 1 site Stand-aloneOther conditions: Insomnia, Insomnia Disorder, Chronic Insomnia, Chronic Insomnia DisorderView official trial listing → -
Recruiting NCT NCT07544355
A Mindfulness-Based Stress Reduction Training Program Model
Not yet reported Istanbul Medeniyet University 93 participants Est. completion 2027-10-30 1 siteOther conditions: Depression, Anxiety, Stress, Well-Being, PsychologicalView official trial listing → -
Recruiting NCT NCT07553143
Effect of Preoperative Melatonin on Quality of Recovery After Elective Laparoscopic Cholecystectomy
Not yet reported Armed Forces Medical Institute Bangladesh 84 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Laparoscopic Cholecystectomy, Postoperative Quality of Recovery, Preoperative Anxiety, Postoperative Sleep Quality, Opioid Consumption, Postoperative, PONV in Laparoscopic CholocystectomiesView official trial listing → -
Recruiting NCT NCT07554703
Chronobiology and Home Parenteral Nutrition Study. CHRONO-HPN Study
Not yet reported Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud 20 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Patients With Home Parenteral NutritionView official trial listing → -
Recruiting NCT NCT07554716
Chronobiology and Enteral Nutrition
Not yet reported Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud 60 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Hospitalised Patients With Enteral NutritionView official trial listing → -
Recruiting NCT NCT07558642
Effects of Stellate Ganglion Block on Delirium and Circadian Rhythm in Geriatric Intensive Care Patients
Not yet reported Antalya Training and Research Hospital 130 participants Est. completion 2027-02-01 2 sitesOther conditions: Stellate Ganglion BlockView official trial listing → -
Recruiting NCT NCT07617922
Melatonin and Solifenacin for Double-J Ureteral Stent Symptoms
Not yet reported Beni-Suef University 189 participants Est. completion 2027-05 1 site Stand-aloneOther conditions: Ureteral Stent-Related Symptoms, Ureteral Calculi, Lower Urinary Tract SymptomsView official trial listing → -
Recruiting NCT NCT07618117
Improving Sleep Health and Circadian Timing to Support Cardiometabolic Health in Adolescents
Not yet reported University of Colorado, Denver 60 participants Est. completion 2030-08-30 1 site Stand-aloneOther conditions: Overweight Adolescents, Sleep, Insulin SensitivityView official trial listing → -
Recruiting NCT NCT07651514
The Effect of a Daily Magnesium and Melatonin Supplement on Sleep Quality in People With Nighttime Leg Cramps
Not yet reported StudySetGo 50 participants Est. completion 2027-09-10 7 sites Stand-aloneOther conditions: Poor Sleep Quality, Leg Cramps, Nocturnal, Melatonin, Magnesium, Muscle CrampsView official trial listing → -
Recruiting NCT NCT07661966
Bright Light Therapy in Patients With Melanoma or Non-small Cell Lung Cancer (NSCLC) Who Are Receiving First-Line Immune Checkpoint Blockade
Not yet reported Weill Medical College of Cornell University 12 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Melanoma (Skin Cancer), NSCLC (Non-small Cell Lung Cancer)View official trial listing → -
Recruiting NCT NCT07695246
Efficacy of CBT-I With Adjuvant Melatonin in Older Adults Chronic Insomnia
Not yet reported The University of Hong Kong 183 participants Est. completion 2029-08-01 1 site Stand-aloneOther conditions: Insomnia, Aging, Sleep DisordersView official trial listing → -
Recruiting NCT NCT07737665
Efficacy of Melatonin Treatment on Sleep Quality Improvement in Inflammatory Bowel Disease Patients With Clinical Remission
Not yet reported Mahidol University 90 participants Est. completion 2027-04-30 1 site Stand-aloneOther conditions: IBD (Inflammatory Bowel Disease)View official trial listing → -
Recruiting NCT NCT07850934
Effect of Melatonin on Pulmonary Hypertension in Full Term Neonates
Not yet reported Ain Shams University 52 participants Est. completion 2026-12-01 1 siteOther conditions: Congenital Peumonia, Persistent Pulmonary Hypertension of Newborn, Congenital Diaphragmatic HerniaView official trial listing → -
Recruiting NCT NCT07853976
Clinical and Radiographic Evaluation of UV-Treated Dental Implants With or Without Melatonin in the Upper Posterior Jaw
Not yet reported Mansoura University 21 participants Est. completion 2026-11-21 1 site Stand-aloneOther conditions: Jaw, Edentulous, Partially, Bone Resorption, Dental Implant FailureView official trial listing → -
Recruiting NCT NCT07859488
Perioperative Biomarkers and Postoperative Delirium in Older Adults Undergoing Abdominal Cancer Surgery
Fatma Cigdem Ozakin 100 participants Est. completion 2027-09-06 1 siteOther conditions: Postoperative Delirium (POD), Abdominal NeoplasmsView official trial listing → -
Recruiting NCT NCT07863232
Melatonin and Immunonutrition for Pain Relief in Fibromyalgia
Not yet reported University of Thessaly 60 participants Est. completion 2027-10 1 site Stand-aloneOther conditions: FibromyalgiaView official trial listing → -
Recruiting NCT NCT07869030
Melatonin Effect on Immediate Dental Implants in the Posterior Mandible
Not yet reported Future University in Egypt 16 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Dental Implant, Immediate Dental Implant Placement, Alveolar Bone Loss, Bone Density, OsseointegrationView official trial listing → -
Completed NCT NCT00000171
Study of Melatonin: Sleep Problems in Alzheimer's Disease
Not yet reported National Institute on Aging (NIA) 31 sitesOther conditions: Alzheimer Disease, DyssomniasView official trial listing → -
Completed NCT NCT00001285
Effects of Sex Hormones on Circadian Rhythm in Men and Women
National Institute of Mental Health (NIMH) 73 participants Est. completion 2000-06 1 siteOther conditions: Bipolar Disorder, Circadian Rhythm, Depressive DisorderView official trial listing → -
Completed NCT NCT00001485
Effects of Season on Melatonin Secretion in Healthy Men and Women and Patients With Seasonal Affective Disorder
National Institute of Mental Health (NIMH) 116 participants Est. completion 2000-04 1 siteOther conditions: Seasonal Affective DisorderView official trial listing → -
Completed NCT NCT00001546
Circadian Regulation of Sleep in Habitual Short Sleepers and Long Sleepers
National Institute of Mental Health (NIMH) 38 participants Est. completion 2000-06 1 siteOther conditions: Sleep DisordersView official trial listing → -
Completed NCT NCT00016666
Clinical Trial of Propranolol for Seasonal Affective Disorder
Not yet reported National Institute of Mental Health (NIMH) 70 participants Est. completion 2007-01-19 1 siteOther conditions: Seasonal Affective Disorder, HealthyView official trial listing → -
Completed NCT NCT00031967
Melatonin and Radiation Therapy in Treating Patients With Brain Metastases
Not yet reported Radiation Therapy Oncology Group 234 sitesOther conditions: Metastatic Cancer, Radiation Toxicity, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00097474
Effects of Hydrocortisone, Melatonin, and Placebo on Jet Lag
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 57 participants Est. completion 2007-11-14 1 site Stand-aloneOther conditions: Jet LagView official trial listing → -
Completed NCT NCT00113906
Melatonin Treatment After Laparoscopic Cholecystectomy
Not yet reported, Not yet reported University Hospital, Gentofte, Copenhagen 200 participants Est. completion 2006-08 2 sitesOther conditions: Postoperative Complications, Fatigue, DyssomniasView official trial listing → -
Completed NCT NCT00200863
Effects of Different Colors of Light on Human Physiology
Not yet reported Brigham and Women's Hospital 47 participants Est. completion 2007-02 1 siteOther conditions: Healthy, Circadian RhythmView official trial listing → -
Completed NCT NCT00230737
Effects of Melatonin on Insomnia Symptoms in Older Adults
Not yet reported Nalaka Gooneratne 27 participants Est. completion 2008-05 1 site Stand-aloneOther conditions: Sleep Initiation and Maintenance DisordersView official trial listing → -
Completed NCT NCT00238108
Melatonin Supplements for Improving Sleep in Individuals With Hypertension
Not yet reported Brigham and Women's Hospital 16 participants Est. completion 2010-08 1 site Stand-aloneOther conditions: Sleep Disorders, HypertensionView official trial listing → -
Status unknown NCT NCT00261183
The Contribution of Melatonin Vs. Placebo in Benzodiazepine Withdrawal in Methadone Maintenance Treatment Patients
Not yet reported Tel-Aviv Sourasky Medical Center 100 participants Est. completion 2006-12 1 siteOther conditions: BenzodiazepinesView official trial listing → -
Active, not recruiting NCT NCT00262470
Treatment of Orthostatic Intolerance
Not yet reported, Not yet reported Satish R. Raj 150 participants Est. completion 2029-12 1 site Stand-aloneOther conditions: Tachycardia, Chronic Orthostatic IntoleranceView official trial listing → -
Status unknown NCT NCT00282061
Synchronization and Desynchronization Between Circadian Rhythms in Patients With Delayed Sleep Phase Syndrome (DSPS)
Not yet reported Sheba Medical Center 1 siteOther conditions: Delayed Sleep Phase SyndromeView official trial listing → -
Status unknown NCT NCT00287794
Quality of Sleep in Patients With Rheumatoid Arthritis
Kobe University 1000 participants Est. completion 2010-12 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00288262
Melatonin Effects on Luteinizing Hormone
Not yet reported, Not yet reported Scripps Health 20 participants Est. completion 2005-02 1 siteOther conditions: Hot FlashesView official trial listing → -
Status unknown NCT NCT00311259
Melatonin Treatment and Inflammation, Oxidative Stress and Autonomic Function in Connection With Surgery
University Hospital, Gentofte, Copenhagen 40 participants Est. completion 2006-11 1 siteOther conditions: Oxidative Stress, Inflammatory Stress, Myocardial IschaemiaView official trial listing → -
Completed NCT NCT00315926
Melatonin and Cardiac Outcome After Major Surgery
Not yet reported, Not yet reported University Hospital, Gentofte, Copenhagen 52 participants Est. completion 2008-07 1 site Stand-aloneOther conditions: Aortic AneurysmView official trial listing → -
Terminated NCT NCT00332670
Light Therapy for Elderly Depression
Not yet reported, Not yet reported GGZ Buitenamstel 89 participants Est. completion 2007-06 1 siteOther conditions: Major Depressive DisorderView official trial listing → -
Completed NCT NCT00376818
Stress Reduction Program in Patients With Malignant Brain Tumors and Their Family Caregivers
Not yet reported Case Comprehensive Cancer Center 4 participants Est. completion 2008-04 1 siteOther conditions: Brain and Central Nervous System Tumors, Psychosocial Effects of Cancer and Its TreatmentView official trial listing → -
Status unknown NCT NCT00387179
Effectiveness of Combining Light and Non-Light Treatments for Jet Lag and Sleep Disorders
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 48 participants Est. completion 2010-03 1 site Stand-aloneOther conditions: Sleep Disorders, Circadian RhythmView official trial listing → -
Completed NCT NCT00388661
Melatonin and Quality of Life in Dialysis Patients
Not yet reported Meander Medical Center 68 participants Est. completion 2009-12 2 sitesOther conditions: Sleep Problems, HaemodialysisView official trial listing → -
Completed NCT NCT00397189
Efficacy and Safety of Circadin® 2 mg in the Treatment of Primary Insomnia Patients
Not yet reported Neurim Pharmaceuticals Ltd. 930 participants Est. completion 2009-04 1 site Stand-aloneOther conditions: Primary InsomniaView official trial listing → -
Completed NCT NCT00404456
The Efficacy of Melatonin in Sleep Problems of Hemodialysis and Peritoneal Dialysis Patients
Not yet reported Meander Medical Center 40 participants Est. completion 2007-07 1 siteOther conditions: Hemodialysis, Peritoneal Dialysis, Sleep ProblemsView official trial listing → -
Suspended NCT NCT00427323
Light Exposure to Treat Sleep Disruption in Older People
Not yet reported National Institute on Aging (NIA) 60 participants Est. completion 2007-09 1 siteOther conditions: Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders, HypersomniaView official trial listing → -
Terminated NCT NCT00444249
Influence of Blue Light Filtering Intraocular Lenses on Daytime Levels of Melatonin
Not yet reported The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery 136 participants Est. completion 2008-08 1 siteOther conditions: Macular DegenerationView official trial listing → -
Completed NCT NCT00470821
Oral Melatonin in Critically Ill High-risk Patients
Not yet reported University of Milan 96 participants Est. completion 2010-05 1 siteOther conditions: Critically Ill Patients, Mechanically Ventilated PatientsView official trial listing → -
Completed NCT NCT00498576
Melatonin and Adiponectin in Hypertensive Kidney Transplant
Sheba Medical Center 60 participants 1 siteOther conditions: Hypertension, Kidney TransplantView official trial listing → -
Terminated NCT NCT00506064
Melatonin Postoperative Sleep Study in Breast Cancer Patients
Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2008-09 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00506259
Treatment Strategies for Children With Smith-Magenis Syndrome
Not yet reported National Human Genome Research Institute (NHGRI) 23 participants Est. completion 2018-05-22 1 siteOther conditions: Developmental Delay Disorders, Chromosome Deletion, Mental Retardation, Sleep Disorders, Circadian Rhythm, Self Injurious BehaviorView official trial listing → -
Completed NCT NCT00507546
Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia
Not yet reported US Department of Veterans Affairs 12 participants Est. completion 2011-07 1 siteOther conditions: Insomnia, Spinal Cord Injury, Tetraplegia, Sleep DisordersView official trial listing → -
Completed NCT NCT00512070
Melatonin Metabolism Abnormality in Patients With Schizophrenia or Schizoaffective Disorder Treated With Olanzapine
Not yet reported Seattle Institute for Biomedical and Clinical Research 40 participants Est. completion 2024-12 1 site Stand-aloneMetabolic syndrome Other conditions: Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, ObesityView official trial listing → -
Completed NCT NCT00513357
Melatonin Versus Placebo and the Effect on Appetite in Advanced Cancer Patients
Not yet reported M.D. Anderson Cancer Center 82 participants Est. completion 2012-12 2 sites Stand-aloneOther conditions: Gastrointestinal Cancer, Lung CancerView official trial listing → -
Status unknown NCT NCT00544791
The Effect of Melatonin on Cognitive Function in Patients Diagnosed With Mild Cognitive Impairment
Not yet reported Assaf-Harofeh Medical Center 50 participants Est. completion 2010-10 1 site Stand-aloneOther conditions: Mild Cognitive Impairment (MCI)View official trial listing → -
Status unknown NCT NCT00564590
SThe Effects of Melatonin on GERD Symptoms
Not yet reported, Not yet reported Rabin Medical Center 150 participants Est. completion 2011-01 1 site Stand-aloneOther conditions: Gastroesophageal Reflux DiseaseView official trial listing → -
Completed NCT NCT00607204
Examining the Biological Factors That Affect Sleep Duration
Brigham and Women's Hospital 119 participants Est. completion 2011-11 1 siteOther conditions: Sleep, Circadian Rhythm, Cognitive PerformanceView official trial listing → -
Terminated NCT NCT00625742
Multimodal Treatment Strategy for Cancer Cachexia
Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2014-06 1 site Stand-aloneOther conditions: Advanced Cancer, CachexiaView official trial listing → -
Terminated NCT NCT00640094
The Melatonin Adjunct in the Acute myocaRdial Infarction Treated With Angioplasty
Not yet reported Alberto Domínguez Rodríguez 272 participants Est. completion 2016-11 3 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00649961
Melatonin As A Novel Neuroprotectant In Preterm Infants- Dosage Study
Not yet reported Imperial College London 18 participants Est. completion 2011-02 2 sites Stand-aloneOther conditions: Premature Birth, Brain InjuryView official trial listing → -
Completed NCT NCT00668707
Adjuvant Melatonin for Prevention of Lung Cancer Recurrence and Mortality
Not yet reported The Canadian College of Naturopathic Medicine 709 participants Est. completion 2017-11-30 8 sites Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT00675181
Effects of Melatonin and Oxygen Consumption and Choroidal Blood Flow
Not yet reported University Hospital, Basel, Switzerland 16 participants Est. completion 2010-01 1 siteOther conditions: Vasospastic SyndromeView official trial listing → -
Terminated NCT NCT00688935
Young Blind Child Melatonin Treatment Study
Not yet reported Oregon Health and Science University 9 participants Est. completion 2015-05 1 site Stand-aloneOther conditions: BlindnessView official trial listing → -
Completed NCT NCT00691080
Understanding Sleep Problems in Children With Autism Spectrum Disorder
Baylor College of Medicine 58 participants Est. completion 2011-11 3 sitesOther conditions: Sleep ProblemsView official trial listing → -
Terminated NCT NCT00691444
Blind Child Melatonin Treatment Study
Not yet reported Oregon Health and Science University 10 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: BlindnessView official trial listing → -
Terminated NCT NCT00691574
Melatonin Levels in Smith Magenis Syndrome (SMS)
Not yet reported Oregon Health and Science University 5 participants Est. completion 2009-05 1 site Stand-aloneOther conditions: Chromosome DisordersView official trial listing → -
Terminated NCT NCT00692094
Blind Elderly Melatonin Treatment Study
Not yet reported Oregon Health and Science University 12 participants Est. completion 2008-12 1 site Stand-aloneOther conditions: BlindnessView official trial listing → -
Completed NCT NCT00698360
Circadian Rhythm of Erythropoietin And Melatonin in Renal Disease
Meander Medical Center 34 participants Est. completion 2008-06 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT00705003
Efficacy and Safety Study of a Combination Product [Drug:BCI-024 (Buspirone) and Drug:BCI-049 (Melatonin)] to Treat Major Depressive Disorder (MDD)
Not yet reported Massachusetts General Hospital 142 participants Est. completion 2008-12 9 sites Stand-aloneOther conditions: Major Depressive DisorderView official trial listing → -
Terminated NCT NCT00739024
A Study of a Melatonin Receptor Agonist to Prevent Migraine
Not yet reported Swedish Medical Center 18 participants Est. completion 2010-09 1 siteOther conditions: Migraine, Migraine With Aura, Migraine Without AuraView official trial listing → -
Status unknown NCT NCT00749814
Sleep Disturbances in Hospitalized Children
Not yet reported Tel-Aviv Sourasky Medical Center 60 participants 1 site Stand-aloneOther conditions: Sleep DisordersView official trial listing → -
Completed NCT NCT00775723
Melatonin Production Delay in Preterm Infants
Tel Aviv University 46 participants Est. completion 2008-05 1 siteOther conditions: Melatonin ProductionView official trial listing → -
Completed NCT NCT00786123
Exploring the Mechanism of a Probiotic Combination VSL#3 in Irritable Bowel Syndrome
Not yet reported National University Hospital, Singapore 40 participants Est. completion 2009-12 1 siteOther conditions: Irritable Bowel SyndromeView official trial listing → -
Terminated NCT NCT00790478
Melatonin and Ulcerative Colitis: A Pilot Clinical Trial
Not yet reported Emory University 3 participants Est. completion 2010-04 2 sitesOther conditions: Ulcerative ColitisView official trial listing → -
Terminated NCT NCT00795236
Melatonin Studies of Totally Blind Children
Not yet reported Oregon Health and Science University 13 participants Est. completion 2015-06 1 site Stand-aloneOther conditions: Sleep Disorder, BlindnessView official trial listing → -
Completed NCT NCT00816673
Sleep Inducing And Maintaining Efficacy Of Circadin In Elderly Insomniacs
Not yet reported Neurim Pharmaceuticals Ltd. 40 participants Est. completion 1997-09 1 site Stand-aloneOther conditions: Primary InsomniaView official trial listing → -
Completed NCT NCT00825591
Biological Clock Dysfunction in Optic Nerve Hypoplasia
Not yet reported Yale University 100 participants Est. completion 2011-09 1 siteOther conditions: Biological Clock Dysfunction, Optic Nerve HypoplasiaView official trial listing → -
Completed NCT NCT00834886
Randomized Controlled Trial on the Treatment Effects of Melatonin and Light Therapy on Delayed Sleep Phase Syndrome
Not yet reported University of Bergen 40 participants Est. completion 2012-01 1 siteOther conditions: Delayed Sleep Phase SyndromeView official trial listing → -
Status unknown NCT NCT00840515
PraevoSkin Emulsion in the Prevention of Radiation Induced Dermatitis
Pharm Olam Pharmaceuticals Ltd. 1 participants Est. completion 2009-08Other conditions: Prevention of Radiation Induced Dermatitis.View official trial listing → -
Completed NCT NCT00849511
Melatonin for Migraine Prevention
Not yet reported Nordlandssykehuset HF 48 participants Est. completion 2009-10 2 sitesOther conditions: MigraineView official trial listing → -
Completed NCT NCT00867451
Improving Sleep and Daytime Functioning Among Children Diagnosed With Attention Deficit Hyperactivity Disorder (ADHD)
Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 8 participants Est. completion 2011-07 1 site Stand-aloneOther conditions: Attention Deficit Hyperactivity DisorderView official trial listing → -
Completed NCT NCT00869128
A Study of the Efficacy of Prolonged-Release Melatonin Versus Placebo in Diabetic Patients Suffering From Insomnia
Not yet reported Neurim Pharmaceuticals Ltd. 36 participants Est. completion 1997-03Type 2 diabetes Other conditions: InsomniaView official trial listing → -
Terminated NCT NCT00869167
Ramelteon for Insomnia Comorbid With Asthma
Not yet reported Northwestern University 2 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Insomnia, AsthmaView official trial listing → -
Withdrawn NCT NCT00869869
Melatonin Supplementation to Improve Sleep in Patients With Heart Failure
Not yet reported Brigham and Women's Hospital Est. completion 2011-03 1 site Stand-aloneHeart failure Other conditions: Sleep DisordersView official trial listing → -
Completed NCT NCT00873379
Melatonin Supplementation for Delirium Prevention in Acutely Hospitalized Elderly
Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 122 participants Est. completion 2008-03 1 siteOther conditions: DeliriumView official trial listing → -
Completed NCT NCT00876499
Fatigue, Sleep and Cytokines in Primary Brain Tumor (PBT) Patients
M.D. Anderson Cancer Center 20 participants Est. completion 2013-12 1 siteOther conditions: Brain CancerView official trial listing → -
Terminated NCT NCT00911053
Melatonin for Circadian Sleep Disorders in the Blind
Not yet reported Oregon Health and Science University 59 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: Insomnia, Blindness, Daytime SleepinessView official trial listing → -
Withdrawn NCT NCT00915616
The Potential Therapeutic Effect of Melatonin in Gastro-Esophageal Reflux Disease
Not yet reported Mansoura UniversityOther conditions: Gastroesophageal Reflux DiseaseView official trial listing → -
Completed NCT NCT00925899
Melatonin for Fatigue and Other Symptoms in Patients With Advanced Cancer
Not yet reported, Not yet reported Bispebjerg Hospital 72 participants Est. completion 2013-03 1 site Stand-aloneOther conditions: Cancer, FatigueView official trial listing → -
Completed NCT NCT00927030
Melatonin for Sleep in Children With Autism
Not yet reported Vanderbilt University 17 participants Est. completion 2010-10 1 site Stand-aloneOther conditions: Autistic Disorder, InsomniaView official trial listing → -
Completed NCT NCT00940550
Study to Investigate the Effects of Melatonin, Temazepam & Zolpidem on Sleep EEG in Men and Women
Not yet reported University of Surrey 16 participants Est. completion 2009-08 1 site Stand-aloneOther conditions: InsomniaView official trial listing → -
Completed NCT NCT00940589
Efficacy of Circadin® 2 mg in Patients With Mild to Moderate Alzheimer Disease Treated With AChE Inhibitor
Not yet reported Neurim Pharmaceuticals Ltd. 73 participants Est. completion 2013-05 6 sites Stand-aloneOther conditions: Alzheimer's Disease, Sleep DisorderView official trial listing → -
Completed NCT NCT00950885
Melatonin Treatment for Induced Transient Insomnia
Not yet reported Brigham and Women's Hospital 42 participants Est. completion 2013-08 1 site Stand-aloneOther conditions: Delayed Sleep Phase Disorder, Jet-lag, Shift-work DisorderView official trial listing → -
Completed NCT NCT00965575
Pilot Study of Melatonin and Epilepsy
Not yet reported Children's Hospital Medical Center, Cincinnati 11 participants Est. completion 2014-08 1 site Stand-aloneOther conditions: EpilepsyView official trial listing → -
Completed NCT NCT00972075
Efficacy and Safety of Circadin for Non-24 Hour Sleep-Wake Disorder in Totally Blind Subjects
Not yet reported Neurim Pharmaceuticals Ltd. 13 participants Est. completion 2007-10 2 sites Stand-aloneOther conditions: Non-24 Hour Sleep-Wake Disorder, BlindnessView official trial listing → -
Status unknown NCT NCT00988078
Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome
Not yet reported Federal University of São Paulo 90 participants Est. completion 2013-12 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01014533
Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence
Not yet reported Dr. Kirk Brower 59 participants Est. completion 2011-09 1 siteAlcohol use disorder Other conditions: InsomniaView official trial listing → -
Terminated NCT NCT01033565
Melatonin CR for the Treatment of Impaired Sleep Maintenance in 4-8 Year Old Children With Autism Spectrum Disorders
Not yet reported University of Nebraska 1 participants Est. completion 2010-10-01 1 site Stand-aloneOther conditions: Sleep DisorderView official trial listing → -
Completed NCT NCT01038921
Melatonin and the Metabolic Syndrome
Not yet reported Emory University 39 participants Est. completion 2013-07 2 sites Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT01064544
Study on Hemodialysis: Illumination Effects
Not yet reported Meander Medical Center 14 participants Est. completion 2010-09 1 siteOther conditions: Sleep ProblemsView official trial listing → -
Completed NCT NCT01087359
Antiinflammatoric and Antioxidative Effect of Melatonin in Human Endotoxaemia
Not yet reported Herlev Hospital 12 participants Est. completion 2011-02 1 site Stand-aloneOther conditions: Human EndotoxaemiaView official trial listing → -
Completed NCT NCT01114360
Melatonin and Nighttime Blood Pressure in African Americans-8 mg Study
Not yet reported Emory University 37 participants Est. completion 2014-09 1 siteOther conditions: HypertensionView official trial listing → -
Completed NCT NCT01114373
Melatonin and Nighttime Blood Pressure in African Americans--24 mg Study
Not yet reported Emory University 40 participants Est. completion 2014-09 1 siteOther conditions: HypertensionView official trial listing → -
Completed NCT NCT01115127
Myo-inositol and Melatonin in Pre-menopausal Women
Not yet reported, Not yet reported University of Messina 90 participants Est. completion 2011-12 1 siteOther conditions: Pre-menopausal Irregular Cycles and BleedingsView official trial listing → -
Status unknown NCT NCT01126294
Perioperative Melatonin in Lumbar Laminectomy
Not yet reported University Health Network, Toronto 84 participants Est. completion 2011-09 1 site Stand-aloneOther conditions: Pain and Anxiety in Patients Undergoing Surgery for Lumbar Laminectomy.View official trial listing → -
Completed NCT NCT01152580
Melatonin Osteoporosis Prevention Study
Not yet reported Duquesne University 19 participants Est. completion 2010-07 1 siteOther conditions: Osteoporosis, OsteopeniaView official trial listing → -
Completed NCT NCT01161108
Trial of Melatonin to Improve Sleep in Children With Epilepsy and Neurodevelopmental Disabilities
Not yet reported The Hospital for Sick Children 13 participants Est. completion 2012-06 1 siteOther conditions: Epilepsy, Insomnia, Developmental DisabilityView official trial listing → -
Completed NCT NCT01171508
Circadian Disturbances After Breast Cancer Surgery
Melissa Voigt Hansen 12 participants Est. completion 2011-11 1 siteOther conditions: Circadian Rhythm Disorders, Anxiety, Breast CancerView official trial listing → -
Completed NCT NCT01172171
The Effect of Melatonin on Ischemia-reperfusion Injury Following Acute Myocardial Infarction
Not yet reported Herlev Hospital 41 participants Est. completion 2016-12 2 sitesCardiovascular disease Other conditions: Ischemia-reperfusion InjuryView official trial listing → -
Status unknown NCT NCT01180855
Effects of Ramelteon (8mg) Alone and in Combination With Multi-Component Behavioral Therapy on Sleep and Circadian Phase in Patients With Chronic Insomnia
Not yet reported University of Arizona 30 participants Est. completion 2010-09 1 siteOther conditions: InsomniaView official trial listing → -
Completed NCT NCT01198938
Postoperative Melatonin Administration and Delirium Prevention in Patients Undergoing Vascular and Cardiac Surgery
Not yet reported University Health Network, Toronto 100 participants Est. completion 2013-02 1 siteOther conditions: Cardiac SurgeryView official trial listing → -
Completed NCT NCT01200641
Evaluation of Anxiolysis and Pain Associated With Retrobulbar Eye Block for Cataract Surgery : Melatonin Versus Gabapentin
Not yet reported, Not yet reported Qazvin University Of Medical Sciences 90 participants Est. completion 2011-01 1 siteOther conditions: Anxiety, PainView official trial listing → -
Status unknown NCT NCT01207050
Effect of Rozerem on Sleep Among People With Traumatic Brain Injury
Not yet reported Kessler Foundation 20 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Insomnia, Brain InjuryView official trial listing → -
Withdrawn NCT NCT01267604
Ovarian Stimulation: Inositol and Melatonin
Not yet reported AGUNCO Obstetrics and Gynecology Centre 2 sites Stand-aloneOther conditions: InfertilityView official trial listing → -
Withdrawn NCT NCT01269671
Efficacy of Combination Therapy vs Placebo for Pediatric Functional Abdominal Pain
Not yet reported Medical College of Wisconsin Est. completion 2012-04 1 site Stand-aloneOther conditions: Functional Abdominal Pain, Irritable Bowel Syndrome, Functional DyspepsiaView official trial listing → -
Completed NCT NCT01279876
Melatonin in Relapsing-Remitting Multiple Sclerosis Patients
Not yet reported Tehran University of Medical Sciences 25 participants Est. completion 2014-02 1 siteOther conditions: Multiple Sclerosis, Relapsing-RemittingView official trial listing → -
Completed NCT NCT01280734
Investigation of Melatonin and Zolpidem Effect on Postural Instability in Healthy Adult Subjects
Not yet reported Neurim Pharmaceuticals Ltd. 26 participants Est. completion 2011-05 1 siteOther conditions: Postural InstabilityView official trial listing → -
Completed NCT NCT01290432
The Potential Effects of Inofolic Plus on Abnormal Ovarian Reserve Parameters in Subfertile Women
Not yet reported Palm Beach Center for Reproductive Medicine 15 participants Est. completion 2012-02 1 site Stand-aloneOther conditions: Infertility, FemaleView official trial listing → -
Completed NCT NCT01311193
Circadian Sleep-wake Cycles and Light Therapy in Borderline Personality Disorder
Not yet reported University Hospital, Basel, Switzerland 1 siteOther conditions: Borderline Personality Disorder, Sleep Disturbances, DepressionView official trial listing → -
Status unknown NCT NCT01325389
Myo-inositol Plus Melatonin in Perimenopausal Women
Not yet reported AGUNCO Obstetrics and Gynecology Centre 1 site Stand-aloneOther conditions: PerimenopauseView official trial listing → -
Completed NCT NCT01327040
Light Sensitization Study
Not yet reported Brigham and Women's Hospital 32 participants Est. completion 2020-12 1 siteOther conditions: Chronobiology Disorders, Circadian Rhythm Disorders, Sleep Disorders, Circadian RhythmView official trial listing → -
Completed NCT NCT01329510
Sleep and Nocturnal Melatonin in Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Not yet reported Assaf-Harofeh Medical Center 19 participants Est. completion 2007-05 1 siteOther conditions: Attention Deficit Hyperactivity DisorderView official trial listing → -
Completed NCT NCT01330992
Human Circadian Sensitivity to Very Short Light Pulses
Not yet reported Brigham and Women's Hospital 400 participants Est. completion 2011-08 1 siteOther conditions: Circadian Rhythm DisordersView official trial listing → -
Completed NCT NCT01340417
Melatonin Levels in Preterm and Term Newborn Infants
Not yet reported Assistance Publique - Hôpitaux de Paris 380 participants Est. completion 2013-06 1 site Stand-aloneOther conditions: Pregnancy PretermView official trial listing → -
Terminated NCT NCT01355523
The Effect of Melatonin on Depression, Anxiety, Cognitive Function and Sleep Disturbances in Breast Cancer Patients
Not yet reported, Not yet reported Melissa Voigt Hansen 54 participants Est. completion 2013-01 1 siteOther conditions: Breast Cancer, DepressionView official trial listing → -
Completed NCT NCT01357031
Study With Amitriptylin to Evaluate the Efficacy of Melatonin in Treatment of Migraine
Not yet reported Hospital Israelita Albert Einstein 192 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: MigraineView official trial listing → -
Completed NCT NCT01357083
The Study of Serum Melatonin Rhythm Levels in Patients With Major Depressive Disorder
Science & Research Islamic Azad University Branch Khozestan 92 participants Est. completion 2010-10 1 siteOther conditions: Major Depressive DisorderView official trial listing → -
Status unknown NCT NCT01360346
Enteral Versus Intravenous Sedation in Critically Ill High-risk ICU Patients
Not yet reported University of Milan 300 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Critical Illness, Mechanical Ventilation ComplicationView official trial listing → -
Withdrawn NCT NCT01370486
Melatonin Versus Placebo in the Lennox-Gastaut Syndrome: Neurophysiological and Neuropsychological Effects
Not yet reported Institution de Lavigny Est. completion 2012-01 1 siteOther conditions: Lennox-Gastaut SyndromeView official trial listing → -
Completed NCT NCT01391390
Melatonin Treatment for Tardive Dyskinesia in Schizophrenia
Not yet reported Beijing HuiLongGuan Hospital 120 participants Est. completion 2011-05 1 site Stand-aloneOther conditions: Tardive DyskinesiaView official trial listing → -
Status unknown NCT NCT01393574
Comparing Treatment With Melatonin to Treatment With Stimulants (Methylphenidate) in Children With Attention Deficit Hyperactivity Disorder and Sleep Difficulties
Not yet reported Assaf-Harofeh Medical Center 46 participants 1 site Stand-aloneOther conditions: Attention Deficit Hyperactivity Disorder, Sleep Onset InsomniaView official trial listing → -
Completed NCT NCT01428661
Melatonin Agonist Effects of Tasimelteon Versus Placebo in Patients With Major Depressive Disorder
Not yet reported, Not yet reported Vanda Pharmaceuticals 507 participants Est. completion 2013-05 40 sitesOther conditions: Major Depressive DisorderView official trial listing → -
Completed NCT NCT01431092
Melatonin Versus Placebo for Benzodiazepine Discontinuation in Patients With Schizophrenia
Not yet reported Lone Baandrup 86 participants Est. completion 2014-06 1 site Stand-aloneOther conditions: Schizophrenia, Schizoaffective Disorder, Bipolar Affective DisorderView official trial listing → -
Completed NCT NCT01450228
Efficacy and Safety of KI1001 in ≥ 55 Years Old Insomnia Patients
Not yet reported Kuhnil Pharmaceutical Co., Ltd. 170 participants Est. completion 2012-03 10 sites Stand-aloneOther conditions: Sleep Initiation and Maintenance DisordersView official trial listing → -
Completed NCT NCT01486615
Premedication With Melatonin and Alprazolam Combination Versus Alprazolam or Melatonin Alone
Not yet reported B.P. Koirala Institute of Health Sciences 80 participants Est. completion 2012-01 2 sitesOther conditions: AnxietyView official trial listing → -
Completed NCT NCT01489969
Sleep Laboratory Study to Investigate the Safety and Efficacy of Neu-P11 in Primary Insomnia Patients
Not yet reported Neurim Pharmaceuticals Ltd. 137 participants Est. completion 2013-01 9 sitesOther conditions: Primary InsomniaView official trial listing → -
Completed NCT NCT01505465
Study of Melatonin on Sleep, Pain, and Confusion After Joint Replacement Surgery
Not yet reported Hospital for Special Surgery, New York 50 participants Est. completion 2013-06 1 site Stand-aloneOther conditions: Postoperative Pain, Delirium, Confusion, SleepView official trial listing → -
Completed NCT NCT01528202
Tart Cherries and Melatonin Content
Not yet reported Northumbria University 20 participants Est. completion 2011-06 1 siteOther conditions: SleepView official trial listing → -
Completed NCT NCT01540747
Role of Melatonin Supplementation in Follicular Fluid of in Vitro Fertilization (IVF) Patients With Polycystic Ovarian Syndrome
Not yet reported AGUNCO Obstetrics and Gynecology Centre 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT01557478
Melatonin as Adjuvant Therapy in Breast Cancer Patients
Not yet reported, Not yet reported Khon Kaen University 166 participants 2 sitesOther conditions: Stage II and III Breast CancerView official trial listing → -
Completed NCT NCT01558284
The Effect of Neu-P11 on Symptoms in Patients With D-IBS
Ludwig-Maximilians - University of Munich 40 participants Est. completion 2014-02 1 siteOther conditions: Diarrhea- Irritable Bowel SyndromeView official trial listing → -
Completed NCT NCT01566474
Melatonin Associated to Acid Inhibition for Chemoprevention in Barret Esophagus: a Pilot Study
Not yet reported Aragon Institute of Health Sciences 80 participants Est. completion 2017-06 1 site Stand-aloneOther conditions: Barrett's EsophagusView official trial listing → -
Completed NCT NCT01570881
Association of Plasma Melatonin Levels With Delirium
Okayama University 33 participants Est. completion 2011-01 1 siteOther conditions: Postoperative DeliriumView official trial listing → -
Completed NCT NCT01572805
Evaluation of Melatonin's Effect on Pain and Blood Loss After Cesarean Section
Not yet reported, Not yet reported Qazvin University Of Medical Sciences 120 participants Est. completion 2012-10 1 siteOther conditions: Post Partum Haemorrhage in Patients Undergoing Cesarean SectionView official trial listing → -
Status unknown NCT NCT01575678
The Effect of Melatonin on Nocturnal Enuresis
Not yet reported University of Aarhus 40 participants Est. completion 2013-08 1 siteOther conditions: Nocturnal EnuresisView official trial listing → -
Completed NCT NCT01586039
Investigating the Effects of Evening Light Exposure on Melatonin Suppression, Alertness and Nocturnal Sleep
Not yet reported Brigham and Women's Hospital 33 participants Est. completion 2014-03 1 site Stand-aloneOther conditions: Non-visual PhotoreceptionView official trial listing → -
Completed NCT NCT01593774
Melatonin for Prevention of Metabolic Side Effects of Olanzapine
Not yet reported Guilan University of Medical Sciences 36 participants Est. completion 2013-03 1 site Stand-aloneOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT01596101
Circadian Rhythm of Melatonin in Burns
Shriners Hospitals for Children 86 participants Est. completion 2014-08 1 siteOther conditions: Sleep, BurnsView official trial listing → -
Terminated NCT NCT01598259
Randomized Controlled Trial to Assess Efficacy of Melatonin for Children During Burn Rehabilitation
Not yet reported Shriners Hospitals for Children 10 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: BurnsView official trial listing → -
Completed NCT NCT01617070
Effects of Kuvan on Melatonin Secretion
Not yet reported University of Southern California 10 participants Est. completion 2014-12 1 siteOther conditions: Phenylketonuria (PKU)View official trial listing → -
Active, not recruiting NCT NCT01628029
Cognitive Behavioral Therapy and Multimodal Therapy in Treating Sleep Disturbance in Patients With Cancer
Not yet reported M.D. Anderson Cancer Center 68 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Sleep DisorderView official trial listing → -
Completed NCT NCT01638234
Effectiveness of Melatonin for Sleep Disturbances in Children With Atopic Dermatitis
Not yet reported, Not yet reported National Taiwan University Hospital 48 participants Est. completion 2013-04 1 site Stand-aloneOther conditions: Atopic DermatitisView official trial listing → -
Completed NCT NCT01690000
Treatment of Osteopenia With Melatonin
Not yet reported University of Aarhus 81 participants Est. completion 2014-06 1 siteOther conditions: OsteoporosisView official trial listing → -
Completed NCT NCT01695070
Melatonin to Prevent Brain Injury in Unborn Growth Restricted Babies
Not yet reported Monash University 16 participants Est. completion 2014-11 1 site Stand-aloneOther conditions: Fetal Growth RetardationView official trial listing → -
Completed NCT NCT01700959
Melatonin Intervention For Neurocognitive Deficits in the St. Jude Lifetime Cohort
Not yet reported St. Jude Children's Research Hospital 911 participants Est. completion 2017-04-19 1 siteOther conditions: Cancer MalignanciesView official trial listing → -
Completed NCT NCT01705639
Melatonin and Glucose Tolerance Among Individuals With a Variant of the MTNR1B Gene
Not yet reported University of Helsinki 45 participants Est. completion 2014-08 2 sites Stand-aloneOther conditions: Diabetes, Glucose ToleranceView official trial listing → -
Completed NCT NCT01706627
Melatonin In Reduction of Chemotherapy-Induced Toxicity (MIRCIT) Trial
Not yet reported, Not yet reported Khon Kaen University 175 participants Est. completion 2012-06 2 sitesOther conditions: Advanced Stage CancerView official trial listing → -
Completed NCT NCT01718678
Effect of Melatonin on Multiple Sclerosis Related Fatigue
Not yet reported Isfahan University of Medical Sciences 44 participants Est. completion 2012-10 1 siteOther conditions: FatigueView official trial listing → -
Completed NCT NCT01724424
Melatonin in Healthy Volunteers
Not yet reported University of Aberdeen 20 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: SepsisView official trial listing → -
Completed NCT NCT01741389
The Role of Melatonin in the Regulation of Blood Coagulation
Not yet reported University of Oslo 12 participants Est. completion 2014-03 1 siteOther conditions: Spinal Cord Injured, TetraplegiaView official trial listing → -
Completed NCT NCT01780883
Melatonin Dose-effect Relation in Childhood Autism
Not yet reported Rennes University Hospital 34 participants Est. completion 2013-09 4 sites Stand-aloneOther conditions: Childhood AutismView official trial listing → -
Completed NCT NCT01784341
Circadian Phase in Bipolar Depression: Is it Delayed and Does it Normalize With Remission?
Northwestern University 10 participants Est. completion 2016-12 1 siteOther conditions: Bipolar DisorderView official trial listing → -
Completed NCT NCT01805089
Melatonin Versus Placebo in Breast Cancer
Not yet reported Dana-Farber Cancer Institute 95 participants Est. completion 2009-07 2 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01811160
Metabolic Effects of Melatonin in Patients Treated With Second Generation Antipsychotics
Not yet reported Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente 50 participants Est. completion 2011-11 1 site Stand-aloneOther conditions: Second Generation Antipsychotic Induced Metabolic Adverse EffectsView official trial listing → -
Completed NCT NCT01855126
Individually Tailored Lighting System to Improve Sleep in Older Adults
Not yet reported Rensselaer Polytechnic Institute 46 participants Est. completion 2017-04 1 siteOther conditions: Sleep DisturbancesView official trial listing → -
Completed NCT NCT01858155
Phase I Dose Finding Study for Melatonin in Pediatric Oncology Patients With Relapsed Solid Tumors
Not yet reported C17 Council 9 participants Est. completion 2017-12-31 5 sites Stand-aloneOther conditions: Relapsed Malignant Solid TumorView official trial listing → -
Status unknown NCT NCT01858909
Efficacy of Melatonin in Patients With Severe Sepsis or Septic Shock
Not yet reported Aragon Institute of Health Sciences 110 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Severe Sepsis, Septic ShockView official trial listing → -
Status unknown NCT NCT01860716
Impact of Melatonin in the Pretreatment of Organ Donor and the Influence in the Evolution of Liver Transplant.
Not yet reported Aragon Institute of Health Sciences 60 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Evidence of Liver TransplantationView official trial listing → -
Status unknown NCT NCT01863277
Safety Study of Melatonin in Stroke Patients
Not yet reported Wolfson Medical Center 140 participants 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01863446
Effects of Light on Melatonin and Contractions in Pregnant Women
Not yet reported Brigham and Women's Hospital 51 participants Est. completion 2023-12 1 siteOther conditions: PregnancyView official trial listing → -
Completed NCT NCT01870115
Melatonin-Micronutrients for Osteopenia Treatment Study
Not yet reported Duquesne University 23 participants Est. completion 2017-02-09 1 siteOther conditions: Osteoporosis, OsteopeniaView official trial listing → -
Completed NCT NCT01873430
The Sun Protective Effect of Melatonin
Not yet reported Herlev Hospital 22 participants Est. completion 2013-08 1 siteOther conditions: SunburnView official trial listing → -
Status unknown NCT NCT01874847
PLAY GAME: Post-concussion Syndrome in Youth - Assessing the GABAergic Effects of Melatonin
Not yet reported, Not yet reported University of Calgary 99 participants Est. completion 2019-09 1 site Stand-aloneOther conditions: Post-concussion Syndrome, Post-concussive Symptoms, Traumatic Brain Injury, Concussion, ChildrenView official trial listing → -
Completed NCT NCT01881854
Sleep Wake and Melatonin Pattern in Craniopharyngioma
Copenhagen University Hospital, Rigshospitalet 30 participants Est. completion 2016-09Other conditions: Sleep Disorders, Circadian Rhythm, CraniopharyngiomaView official trial listing → -
Completed NCT NCT01903681
Assessment of the Pharmacokinetics of Circadin® in Children With Neurodevelopmental Disorders and Sleep Disturbances
Not yet reported Neurim Pharmaceuticals Ltd. 16 participants Est. completion 2014-04 1 siteOther conditions: Sleep ProblemsView official trial listing → -
Withdrawn NCT NCT01904786
Melatonin Treatment for Newborn Infants With Moderate to Severe Hypoxic Ischemic Encephalopathy
Not yet reported St. Louis University Est. completion 2018-11 1 site Stand-aloneOther conditions: Newborn Hypoxic Ischemic EncephalopathyView official trial listing → -
Completed NCT NCT01906866
Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities
Not yet reported Neurim Pharmaceuticals Ltd. 125 participants Est. completion 2018-03-27 28 sitesOther conditions: Sleep DisordersView official trial listing → -
Status unknown NCT NCT01922999
Different Doses of Oral Melatonin Supplements in Chronic Kidney Disease (CKD)-Associated Sleep Disorders
Not yet reported, Not yet reported Southeast Renal Research Institute 53 participants Est. completion 2017-12 1 siteChronic kidney disease Other conditions: End Stage Renal Disease, Sleep DisorderView official trial listing → -
Completed NCT NCT01923974
The Analgesic Effects of Melatonin
Not yet reported, Not yet reported Lars Peter Holst Andersen 36 participants Est. completion 2014-08 1 siteOther conditions: Analgesia, AntihyperalgesiaView official trial listing → -
Completed NCT NCT01965522
Anti-proliferative Effects of Vitamin D and Melatonin in Breast Cancer
Not yet reported Juravinski Cancer Center 100 participants Est. completion 2017-05 2 sites Stand-aloneOther conditions: Early Stage Breast CancerView official trial listing → -
Completed NCT NCT01993251
Does Melatonin Restore Sleep Architecture in Autistic Children
Not yet reported Hospices Civils de Lyon 26 participants Est. completion 2018-06-12 5 sitesOther conditions: Sleep DisordersView official trial listing → -
Status unknown NCT NCT02041455
Immune-Pineal Axis Function in Fibromyalgia
Not yet reported, Not yet reported Hospital de Clinicas de Porto Alegre 66 participants Est. completion 2014-03 1 site Stand-aloneOther conditions: FibromyalgiaView official trial listing → -
Completed NCT NCT02071160
Melatonin for Neuroprotection Following Perinatal Asphyxia
Not yet reported, Not yet reported Tanta University 45 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Perinatal AsphyxiaView official trial listing → -
Completed NCT NCT02087722
Efficacy and Safety of KI1001 in the Treatment of ≥ 55 Years Old Insomnia Patients
Not yet reported Kuhnil Pharmaceutical Co., Ltd. 80 participants Est. completion 2014-01 4 sitesOther conditions: Sleep Initiation and Maintenance DisordersView official trial listing → -
Withdrawn NCT NCT02099331
Cardiac Surgery and the Risk of Atrial Fibrillation: an Intervention Trial Evaluating Melatonin
Not yet reported Johns Hopkins University Est. completion 2015-07-06 1 site Stand-aloneOther conditions: Atrial FibrillationView official trial listing → -
Completed NCT NCT02107079
The Relative Bio-availability of Oral and Oromucosal Melatonin in Different Formulations in Healthy Human Volunteers.
Not yet reported Utrecht University 10 participants Est. completion 2012-01 1 siteOther conditions: Pharmacokinetics of MelatoninView official trial listing → -
Completed NCT NCT02108353
Circadian Phase Adjustment and Improvement of Metabolic Control in Night Shift Workers
Not yet reported Universitätsklinikum Hamburg-Eppendorf 46 participants Est. completion 2017-03-29 3 sitesOther conditions: Sleep Disorders, Circadian RhythmView official trial listing → -
Completed NCT NCT02156271
Mechanisms of Sleep Latency and Health: The Effect of a Melatonin Receptor Agonist in Inflammation and Insulin Resistance
Not yet reported Duke University 75 participantsOther conditions: InsomniaView official trial listing → -
Status unknown NCT NCT02180451
Observational Study to Investigate the Melatonin and Cortisol Circadian Rhythms of Individuals With Smith-Magenis Syndrome (SMS)
Vanda Pharmaceuticals 8 participants Est. completion 2017-01 1 siteOther conditions: Smith Magenis SyndromeView official trial listing → -
Completed NCT NCT02186392
The Impact of Ergonomic Circadian Light on Hospitalized Stroke Patients in a Rehabilitation Unit
Not yet reported Glostrup University Hospital, Copenhagen 90 participants Est. completion 2016-08-15 1 siteCardiovascular diseaseObstructive sleep apnea Other conditions: Depression, AnxietyView official trial listing → -
Terminated NCT NCT02190838
Comparison of Melatonin or Metformin and Dacarbazine Combination Versus Dacarbazine Alone in Disseminated Melanoma
Not yet reported N.N. Petrov National Medical Research Center of Oncology 57 participants Est. completion 2018-12-31 3 sites Stand-aloneOther conditions: MelanomaView official trial listing → -
Status unknown NCT NCT02195271
Neuroplasticity:Melatonin and Transcranial Current Stimulation in Healthy Subjects.
Not yet reported Hospital de Clinicas de Porto Alegre 50 participants Est. completion 2014-08 1 siteOther conditions: Analgesia Disorder, PainView official trial listing → -
Completed NCT NCT02195661
The Role of Melatonin in the Effective Attainment of Sleep Electroencephalograms (EEG) in Children
Not yet reported University of Cape Town 194 participants Est. completion 2017-10 1 siteOther conditions: Epilepsy, Electroencephalogram, Children, SedationView official trial listing → -
Completed NCT NCT02200172
The Preventative Role of Exogenous Melatonin Administration in Patients With Advanced Cancer Who Are at Risk of Delirium: a Feasibility Study
Not yet reported Bruyère Health Research Institute. 60 participants Est. completion 2016-04 1 siteOther conditions: CancerView official trial listing → -
Completed NCT NCT02224937
MELATOX: Evaluation of Percutaneous Dissolvement of Melatonin When Used as Sunscreen; a Randomized, Placebo Controlled, Double-blind Crossover Study on Healthy Volunteers.
Not yet reported Zealand University Hospital 10 participants 1 site Stand-aloneOther conditions: Solar Skin DamageView official trial listing → -
Completed NCT NCT02251041
Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL)
Not yet reported Universitaire Ziekenhuizen KU Leuven 143 participants Est. completion 2019-08 1 siteOther conditions: Reperfusion InjuryView official trial listing → -
Completed NCT NCT02265822
Melatonin Premedication in Children Undergoing Surgery
Not yet reported Azienda Ospedaliera Universitaria Policlinico "G. Martino" 92 participants Est. completion 2013-10 Stand-aloneOther conditions: Premedication, AnaesthesiaView official trial listing → -
Withdrawn NCT NCT02282241
Melatonin for Delirium Prophylaxis
Not yet reported University of British Columbia Est. completion 2021-09 1 site Stand-aloneOther conditions: DeliriumView official trial listing → -
Status unknown NCT NCT02304224
the Relationship of the Use of Eye Masks and Outcomes of Patients With Sepsis in Intensive Care Unit
Not yet reported Shanghai 10th People's Hospital 100 participants Est. completion 2016-02 1 siteOther conditions: Sepsis, Sleep Deprivation, Immune SuppressionView official trial listing → -
Withdrawn NCT NCT02319265
Dose Assessment of Melatonin in Sepsis Trial
Not yet reported, Not yet reported University of Aberdeen Est. completion 2019-12 1 site Stand-aloneOther conditions: SepsisView official trial listing → -
Completed NCT NCT02321449
The Effectiveness of Circadin in Improving Quality of Sleep in Patients Aged 55 or Over
Ipsen 40 participants Est. completion 2015-02 3 sitesOther conditions: InsomniaView official trial listing → -
Terminated NCT NCT02332928
Melatonin Supplementation for Cancer-related Fatigue in Patients Receiving Radiotherapy
Not yet reported Virginia Commonwealth University 80 participants Est. completion 2021-06-02 1 siteOther conditions: Breast Cancer - FemaleView official trial listing → -
Withdrawn NCT NCT02333149
Melatonin in Youth: N-of-1 Trials in a Stimulant-treated Attention Deficit Hyperactivity Disorder (ADHD) Population
Not yet reported University of Alberta Est. completion 2021-11-04 1 site Stand-aloneOther conditions: Attention Deficit/Hyperactivity Disorder, Initial InsomniaView official trial listing → -
Completed NCT NCT02344316
Bringing Relief to Adolescents Naturally Using Melatonin for Migraine
Not yet reported Amy Gelfand 31 participants Est. completion 2016-04 2 sitesOther conditions: Migraine in AdolescentsView official trial listing → -
Status unknown NCT NCT02359448
Melatonin for Nocturia in Parkinson's Disease
Not yet reported University College, London 20 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: Parkinson's Disease, NocturiaView official trial listing → -
Completed NCT NCT02373189
Bright Light Treatment At Home To Manage Chronic Pain In U.S. Veterans
Not yet reported Rush University Medical Center 37 participants Est. completion 2018-02 1 site Stand-aloneOther conditions: Chronic Low Back PainView official trial listing → -
Terminated NCT NCT02374567
Pharmacovigilance in Gerontopsychiatric Patients
Not yet reported Hannover Medical School 407 participants Est. completion 2017-06-28 5 sites Stand-aloneOther conditions: Dementia, Depression, Schizophrenia, Psychosomatic Disorders, Anxiety DisordersView official trial listing → -
Completed NCT NCT02386319
Anxiolytic and Analgesic Effects of Melatonin
Not yet reported Herlev Hospital 36 participants Est. completion 2021-04 1 siteOther conditions: AnxietyView official trial listing → -
Terminated NCT NCT02395783
Therapeutic Effects of Maternal Melatonin Administration on Brain Injury and White Matter Disease
Not yet reported, Not yet reported Assistance Publique - Hôpitaux de Paris 14 participants Est. completion 2018-02 1 siteOther conditions: Premature BirthView official trial listing → -
Status unknown NCT NCT02403921
Association Between Cortisol, Cortisone, Cotinine, Nicotine, Caffeine, Melatonin Levels in Hair, Serum, Urine, Saliva and Chronic Stress
National Taiwan University Hospital 80 participants Est. completion 2016-01 1 siteOther conditions: HydrocortisoneView official trial listing → -
Completed NCT NCT02415309
Premedication With Melatonin in Lumbar Medial Branch Block Procedure
Not yet reported United States Naval Medical Center, San Diego 25 participants Est. completion 2022-05 2 sitesOther conditions: AnxietyView official trial listing → -
Completed NCT NCT02424071
The Effect of Premedication With Melatonin on Postoperative Recovery From Bariatric Surgery
Not yet reported Sheba Medical Center 60 participants Est. completion 2016-04 1 siteOther conditions: Recovery From Bariatric SurgeryView official trial listing → -
Completed NCT NCT02430298
Topical/Oral Melatonin for Preventing Concurrent Radiochemotherapy Induced Oral Mucositis/Xerostomia Cancer Patients
Not yet reported Khon Kaen University 39 participants Est. completion 2015-12 1 siteOther conditions: Head and Neck CancerView official trial listing → -
Completed NCT NCT02431728
The Effect of Melatonin Upon Post-Acute Withdrawal Among Males in a Residential Treatment Program
Not yet reported, Not yet reported Duquesne University 70 participants Est. completion 2016-01 1 siteOther conditions: Substance Withdrawal SyndromeView official trial listing → -
Completed NCT NCT02451293
The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome
Not yet reported, Not yet reported Zealand University Hospital 252 participants Est. completion 2018-07-20 6 sitesOther conditions: Depression, Acute Coronary SyndromeView official trial listing → -
Terminated NCT NCT02454855
Impact of a Melatonin Supplementation on the Quality of Life in Elderly Metastatic Cancer Patients
Not yet reported Centre Jean Perrin 123 participants Est. completion 2022-02 12 sites Stand-aloneOther conditions: CancerView official trial listing → -
Completed NCT NCT02463318
The Effect of Melatonin on Gene Expression and Activity of the Sirt1 and Its Target Genes Catalase and MnSOD in Multiple Sclerosis Patients and Healthy Subjects
Not yet reported Tehran University of Medical Sciences 34 participants Est. completion 2015-09 1 site Stand-aloneOther conditions: Multiple Sclerosis, Oxidative StressView official trial listing → -
Completed NCT NCT02483559
Seeing the World Through Assorted Glasses
Not yet reported University of North Carolina, Chapel Hill 15 participants Est. completion 2016-05 1 siteOther conditions: SleepView official trial listing → -
Completed NCT NCT02484300
The Effect of Melatonin on Sleep and Ventilatory Control in Obstructive Sleep Apnea
Not yet reported University of California, San Diego 20 participants Est. completion 2017-11 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Terminated NCT NCT02486796
Immediate or Delayed Naturopathic Medicine in Combination With Neo-Adjuvant Chemotherapy for Breast Cancer
Not yet reported, Not yet reported Midwestern Regional Medical Center 5 participants Est. completion 2017-03-03Other conditions: Quality of LifeView official trial listing → -
Terminated NCT NCT02487082
Pilot Study of Sleep Therapy and Biomarkers in Children With Autism Spectrum Disorders
Not yet reported Stony Brook University 12 participants Est. completion 2021-01-29 1 siteOther conditions: Autism Spectrum DisorderView official trial listing → -
Terminated NCT NCT02500017
Melatonin Treatment for Night-Eating Syndrome
Not yet reported Yale University 2 participants Est. completion 2017-04-25 1 site Stand-aloneOther conditions: Night-eating SyndromeView official trial listing → -
Status unknown NCT NCT02506777
Neoadjuvant FDC With Melatonin or Metformin for Locally Advanced Breast Cancer.
Not yet reported N.N. Petrov National Medical Research Center of Oncology 96 participants Est. completion 2020-08 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT02506790
Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer
Not yet reported N.N. Petrov National Medical Research Center of Oncology 96 participants Est. completion 2022-08 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02536417
Efficacy of Melatonin in Decreasing the Incidence of Delirium in End of Life Patients
Not yet reported Fraser Health 19 participants Est. completion 2020-09 1 siteOther conditions: DeliriumView official trial listing → -
Completed NCT NCT02560324
Effect of Ramelteon on Smoking Abstinence
Not yet reported University of Pennsylvania 140 participants Est. completion 2018-08 1 siteOther conditions: Tobacco Use DisorderView official trial listing → -
Completed NCT NCT02580734
Efficacy of Melatonin in Burning Mouth Syndrome (BMS)
Not yet reported University of Milan 20 participants Est. completion 2015-10 Stand-aloneOther conditions: Burning Mouth SyndromeView official trial listing → -
Terminated NCT NCT02588742
The Effect of Melatonin on Postoperative Delirium in Elderly ICU Patients
Not yet reported Yonsei University 3 participants Est. completion 2016-01-15 1 site Stand-aloneOther conditions: DeliriumView official trial listing → -
Completed NCT NCT02591238
Melatonin in Smoke-induced Vascular Injury
Not yet reported Peking Union Medical College Hospital 68 participants Est. completion 2015-10 1 siteOther conditions: Smoking, Vascular System InjuriesView official trial listing → -
Completed NCT NCT02597231
Melatonin and Sleep in Preventing Delirium in the Hospital
Not yet reported, Not yet reported Scripps Health 94 participants Est. completion 2016-12-31 1 site Stand-aloneOther conditions: DeliriumView official trial listing → -
Completed NCT NCT02604095
Effect of Melatonin on Body Composition, Glucose Metabolism and Lipid Metabolism
Not yet reported Shanghai 10th People's Hospital 16 participants Est. completion 2015-10 1 site Stand-aloneOther conditions: Acanthosis Nigricans, ObesityView official trial listing → -
Status unknown NCT NCT02615340
Melatonin for Prevention of Delirium in Critically Ill Patients
Not yet reported Mount Sinai Hospital, Canada 69 participants Est. completion 2019-10-12 3 sitesOther conditions: DeliriumView official trial listing → -
Completed NCT NCT02630004
Melatonin Oral Gel for Oral Mucositis in Patients With Head and Neck Cancer Undergoing Chemoradiation
Not yet reported, Not yet reported Spherium Biomed 84 participants Est. completion 2017-12-22 11 sites Stand-aloneOther conditions: Oral MucositisView official trial listing → -
Terminated NCT NCT02631148
Effects of Melatonin Supplementation on Renal Physiology in a Habitual Sleep Restricted Population.
Not yet reported Brigham and Women's Hospital 12 participants Est. completion 2017-12-31 1 site Stand-aloneOther conditions: Obesity, Prediabetic StateView official trial listing → -
Completed NCT NCT02639741
Preoperative Melatonin or Vitamin C Administration on Postoperative Analgesia
Not yet reported Cukurova University 55 participants Est. completion 2020-12-30 1 siteOther conditions: Postoperative PainView official trial listing → -
Completed NCT NCT02642640
Interaction of Melatonin and MTNR1B Genotype on Glucose Control - Study 1
Not yet reported Brigham and Women's Hospital 23 participants Est. completion 2022-03-24 1 siteOther conditions: Glucose, Circadian Rhythm, Melatonin, GenesView official trial listing → -
Status unknown NCT NCT02644590
The Effect of Melatonin on Early Signs of Hypertension in Teenagers With Diabetes Mellitus Type 1
Not yet reported Sheba Medical Center 30 participants Est. completion 2017-02 Stand-aloneOther conditions: Diabetes Mellitus, Type 1, HypertensionView official trial listing → -
Terminated NCT NCT02654314
Prevention of Delirium in Inpatients Utilizing Melatonin
Not yet reported Yale University 277 participants Est. completion 2017-11-03 1 site Stand-aloneOther conditions: DeliriumView official trial listing → -
Status unknown NCT NCT02663570
Effects of Melatonin in PCOS Women
Not yet reported Catholic University of the Sacred Heart 40 participants 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT02681887
Effect of Melatonin on Cardiometabolic Risk- FULL
Not yet reported Brigham and Women's Hospital 120 participants Est. completion 2021-12 1 site Stand-aloneOther conditions: Obesity, Prediabetic StateView official trial listing → -
Completed NCT NCT02691702
Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers
Not yet reported Biogen 97 participants Est. completion 2017-01-12 2 sites Stand-aloneOther conditions: Healthy Adult Subjects, Healthy Elderly SubjectsView official trial listing → -
Status unknown NCT NCT02691897
Melatonin's Effects on Treatment Of Diabetes Mellitus
Not yet reported Shiraz University of Medical Sciences 60 participants Est. completion 2020-07 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02726126
Transdermal Fentanyl and Melatonin Patches for Postoperative Pain Relief
Ain Shams University 75 participants Est. completion 2015-04Other conditions: Postoperative PainView official trial listing → -
Terminated NCT NCT02732288
Exploratory Study of Melatonin Induced Sleep Regularization in Severe Brain Injury
Not yet reported Rockefeller University 1 participants Est. completion 2018-06-19 1 site Stand-aloneOther conditions: Disorders of ConsciousnessView official trial listing → -
Completed NCT NCT02747628
Transdermal Nicotine and Melatonin Patches for Postoperative Pain Relief
Not yet reported Ain Shams University 60 participants Est. completion 2015-07Other conditions: Postoperative Pain ReliefView official trial listing → -
Completed NCT NCT02750631
Out-patient Wake Therapy, Light Therapy and Sleep Phase Advance for Depression
Not yet reported New York State Psychiatric Institute 30 participants Est. completion 2017-07 1 siteOther conditions: Unipolar DepressionView official trial listing → -
Completed NCT NCT02757066
Verification of the Efficacy of NPC-15 for Sleep Disorders of Children With Autism Spectrum Disorders
Not yet reported, Not yet reported Nobelpharma 196 participants Est. completion 2018-09-14 Stand-aloneOther conditions: Sleep Disorders, Autism Spectrum DisorderView official trial listing → -
Completed NCT NCT02757079
Study of the Efficacy and Safety of NPC-15 for Sleep Disorders of Children With Neurodevelopmental Disorders
Not yet reported Nobelpharma 99 participants Est. completion 2018-07-06 Stand-aloneOther conditions: Sleep Disorders, Neurodevelopmental DisorderView official trial listing → -
Completed NCT NCT02767102
Bioavailability and Bioactivity of Red Wine Melatonin in Humans
Not yet reported University of Milan 12 participants Est. completion 2015-07 1 site Stand-aloneOther conditions: BioavailabilityView official trial listing → -
Status unknown NCT NCT02768077
Effect of Melatonin on Sleep Disturbances in Patients With Parkinson's Disease
Not yet reported Kuhnil Pharmaceutical Co., Ltd. 100 participants Est. completion 2017-02 Stand-aloneOther conditions: Parkinson's DiseaseView official trial listing → -
Completed NCT NCT02776215
Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents
Not yet reported Vanda Pharmaceuticals 24 participants Est. completion 2017-12-20 1 site Stand-aloneOther conditions: Circadian Rhythm Sleep Disorders, Non-24 Hour Sleep-Wake Disorder, Autism Spectrum Disorder, Smith-Magenis SyndromeView official trial listing → -
Status unknown NCT NCT02789592
Efficacy and Safety of Melatonin PR and Clonazepam in Patients With REM Sleep Behavior Disorder in Parkinson Disease
Not yet reported Seoul National University Hospital 30 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: REM Sleep Behavior Disorder, Parkinson DiseaseView official trial listing → -
Status unknown NCT NCT02798367
Melatonin 3mg and 5mg Compared to Cognitive Behavioral Therapy for Insomnia (CBT-I) in the Treatment of Insomnia
Not yet reported, Not yet reported Ache Laboratorios Farmaceuticos S.A. 307 participants Est. completion 2021-11-30 8 sites Stand-aloneOther conditions: Insomnia DisorderView official trial listing → -
Status unknown NCT NCT02824770
Effects of Sleep Quality on Melatonin Levels and Inflammatory Response After Major Abdominal Surgery
Not yet reported Eskisehir Osmangazi University 40 participants Est. completion 2017-07-01 1 siteOther conditions: Sleep DeprivationView official trial listing → -
Status unknown NCT NCT02836743
Effect of Slow-release Melatonin (Circadin®) Therapy on Idiopathic RBD: a Pilot Study
Not yet reported Seoul National University Hospital 30 participants Est. completion 2017-12-31 1 site Stand-aloneOther conditions: REM Sleep Behavior DisorderView official trial listing → -
Completed NCT NCT02839395
The Effects of Acute vs. Chronic of Screen Illumination on: Sleep Efficacy and Architecture, Physiology, Emotion and Behavior: Possible Effect on Human Health
Not yet reported Assuta Medical Center 19 participants Est. completion 2016-12Other conditions: Sleep, EmotionView official trial listing → -
Status unknown NCT NCT02845778
Pharmacokinetics of Melatonin Niosomes Oral Gel in Healthy Volunteers
Not yet reported, Not yet reported Khon Kaen University 15 participants Est. completion 2017-03 1 site Stand-aloneOther conditions: Pharmacokinetics of MelatoninView official trial listing → -
Terminated NCT NCT02876770
Melatonin Supplementation and Performance
Not yet reported kais 12 participants Est. completion 2013-01 Stand-aloneOther conditions: Motor ActivityView official trial listing → -
Status unknown NCT NCT02878499
Do Sleep and Circadian Rhythm Disturbances Impact the Cognitive and Behavioural Development of Children With Autism?
Not yet reported University Hospital, Strasbourg, France 105 participants Est. completion 2023-02 5 sitesOther conditions: Autism Spectrum DisorderView official trial listing → -
Terminated NCT NCT02883790
Effects of Somnage® in the Management on Sleep and Mood in Cancer Patients
Not yet reported Helsinn Healthcare SA 3 participants Est. completion 2018-02 5 sites Stand-aloneOther conditions: Breast Cancer, Lung Cancer, Colon CancerView official trial listing → -
Status unknown NCT NCT02889432
Effects of Oral Melatonin on Neurosensory Recovery Following Facial Osteotomies
Not yet reported The University of Hong Kong 40 participants Est. completion 2017-09 1 site Stand-aloneOther conditions: Dentofacial DeformitiesView official trial listing → -
Withdrawn NCT NCT02903901
Melatonin for Prevention of Post- Operative Delirium Pilot Study Protocol
Not yet reported Loyola University Est. completion 2018-06 1 siteOther conditions: DeliriumView official trial listing → -
Completed NCT NCT02936674
Color-dependent Melatonin Suppression
Not yet reported VA Palo Alto Health Care System 10 participants Est. completion 2017-06 1 site Stand-aloneOther conditions: MelatoninView official trial listing → -
Terminated NCT NCT02940769
Neurobiological Effects of Light on MDD
Not yet reported University of Michigan 7 participants Est. completion 2017-02-14 1 siteOther conditions: Major Depressive DisorderView official trial listing → -
Completed NCT NCT02957383
Evning Exposure to Computer Screen Disrupts Sleep, Attention and Biological Rhythms
Not yet reported Assuta Medical Center 19 participants Est. completion 2016-08Other conditions: Sleep DisorderView official trial listing → -
Status unknown NCT NCT02962037
Are Patients Suffering From DSPS Show Compromising in Everyday Functions and Abilities Before Handling the Disorder?
Not yet reported Lilach Kemer 20 participants Est. completion 2017-11 Stand-aloneOther conditions: Delayed Sleep Phase SyndromeView official trial listing → -
Terminated NCT NCT02963181
Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic Hypotension
Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 10 participants Est. completion 2019-05-28 1 site Stand-aloneOther conditions: Hypotension, Orthostatic, Hypertension, Autonomic Nervous System DiseasesView official trial listing → -
Status unknown NCT NCT02993588
Impact of Melatonin on IVF/ICSI Outcomes in Prospective Poor Responders
Not yet reported, Not yet reported Assiut University 100 participants 2 sites Stand-aloneOther conditions: In Vitro Fertilization, Poor Ovarian ResponseView official trial listing → -
Completed NCT NCT03000777
Oral Melatonin Plus Zinc Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)
Not yet reported Laboratorios Viñas, S.A. 60 participants Est. completion 2017-09 1 site Stand-aloneOther conditions: Fatigue Syndrome, Chronic, Myalgic EncephalomyelitisView official trial listing → -
Completed NCT NCT03003936
Glucose Tolerance, Meal Timing and MTNR1B
Not yet reported Universidad de Murcia 280 participants Est. completion 2017-06 1 site Stand-aloneOther conditions: Non-Diabetic Disorder of Endocrine PancreasView official trial listing → -
Status unknown NCT NCT03013790
Melatonin Use in the Intensive Care Elderly Population
Not yet reported MICE Trial Group 600 participants Est. completion 2018-01 1 siteOther conditions: Delirium, MelatoninView official trial listing → -
Completed NCT NCT03014245
Melatonin in Pregnancy Compared to Non-pregnant
University of Aberdeen 60 participants Est. completion 2017-05-18 1 siteOther conditions: Pregnancy Transient HypertensionView official trial listing → -
Completed NCT NCT03043443
Melatonin Use for Sleep Problems in Alcohol Dependent Patients
Not yet reported Centre for Addiction and Mental Health 60 participants Est. completion 2019-01-10 2 sitesOther conditions: Alcohol-Related DisordersView official trial listing → -
Status unknown NCT NCT03062839
Melatonin as Adjuvant Treatment for ADHD in Adults
Not yet reported Hospital Israelita Albert Einstein 120 participants Est. completion 2019-06-30 1 site Stand-aloneOther conditions: Attention Deficit Hyperactivity DisorderView official trial listing → -
Completed NCT NCT03066518
Effect of Melatonin on Sleep Quality in Patients Dementia
Not yet reported Hospital Universitario Dr. Jose E. Gonzalez 40 participants Est. completion 2017-01-25Other conditions: Sleep Disorders, DementiaView official trial listing → -
Status unknown NCT NCT03107702
Melatonin Level and Postoperative Analgesia Consumption in Bariatric Surgery Patients.
Inonu University 35 participants Est. completion 2017-07-30 1 siteOther conditions: Bariatric Surgery, Melatonin, POSTOPERATIVE PAINView official trial listing → -
Status unknown NCT NCT03109054
Endogenous Melatonin Level and Pre- Postoperative Anxiety in Bariatric Surgery Patients.
Inonu University 50 participants Est. completion 2017-06-15 1 siteOther conditions: Anxiety Disorders, MelatoninView official trial listing → -
Active, not recruiting NCT NCT03114072
Blocking Blue Light in Pregnancy, Effects on Melatonin Profile and Sleep
Not yet reported University of Bergen 60 participants Est. completion 2026-07 1 siteOther conditions: Sleep DisturbanceView official trial listing → -
Completed NCT NCT03115034
Melatonin in Patients Under Carotid Endarterectomy
Not yet reported Peking Union Medical College Hospital 60 participants Est. completion 2017-11-01 1 siteOther conditions: Carotid StenosisView official trial listing → -
Status unknown NCT NCT03117725
Melatonin Study Between Diminished and Normal Responder in IVF
Not yet reported Bundang CHA Hospital 100 participants Est. completion 2019-10-31 1 site Stand-aloneOther conditions: Infertility, FemaleView official trial listing → -
Completed NCT NCT03121521
The Effects of Melatonin on Elevated Liver Enzymes During Statins Treatment
Not yet reported Medical University of Lodz 60 participants Est. completion 2016-12-15 Stand-aloneOther conditions: HepatopathyView official trial listing → -
Terminated NCT NCT03150797
Melatonin for Adolescent Migraine Prevention Study
Not yet reported Amy Gelfand 72 participants Est. completion 2019-12-01 2 sites Stand-aloneOther conditions: MigraineView official trial listing → -
Completed NCT NCT03153917
Biological Rhythms Impact of 12 Hours Shift Work
Not yet reported Hospices Civils de Lyon 15 participants Est. completion 2017-07-28 1 site Stand-aloneOther conditions: Shift-Work Sleep DisorderView official trial listing → -
Completed NCT NCT03156205
Effects of Patient-Directed Interactive Music Therapy on Sleep, Delirium and Melatonin Levels is Critically Ill Elderly Patients
Not yet reported Yonsei University 152 participants Est. completion 2017-09-25 1 siteOther conditions: Critically Ill Adult Patients in Intensive Care UnitsView official trial listing → -
Completed NCT NCT03167801
Melatonin Secretion and Sleep Quality in Spinal Cord Injury Patients
Centre d'Investigation Clinique et Technologique 805 18 participants Est. completion 2018-07-31 1 siteOther conditions: Spinal Cord InjuriesView official trial listing → -
Completed NCT NCT03178396
Effects and Mechanisms of Melatonin on Blood Pressure, Insulin Resistance, and Platelets
Not yet reported Thomas Jefferson University 31 participants Est. completion 2016-08-09 1 site Stand-aloneOther conditions: Prehypertension, HealthyView official trial listing → -
Completed NCT NCT03193112
Melatonin Decreases Eye Pressure in Normotensive Patients
Kahramanmaras Sutcu Imam University 20 participants Est. completion 2018-06-15 1 siteOther conditions: Depressive DisorderView official trial listing → -
Status unknown NCT NCT03202121
Relationship of Nocturnal Concentrations of Melatonin, γ-aminobutyric Acid and Total Antioxidants With Insomnia
China Rehabilitation Research Center 75 participants Est. completion 2019-03Other conditions: InsomniaView official trial listing → -
Completed NCT NCT03203538
Light Intervention for Adaptation to Night Work
Not yet reported University of Bergen 97 participants Est. completion 2019-03-27 1 site Stand-aloneOther conditions: Shift-Work Related Sleep Disturbance, Sleep Deprivation, SleepView official trial listing → -
Completed NCT NCT03204877
Acute Metabolic Effects of Melatonin Treatment
Not yet reported, Not yet reported University of Aarhus 36 participants Est. completion 2020-02-01 1 siteOther conditions: Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT03205033
Melatonin as a Circadian Clock Regulator, Neuromodulator and Myelo-protector in Adjuvant Breast Cancer Chemotherapy
Not yet reported Hospital de Clinicas de Porto Alegre 36 participants Est. completion 2017-01Other conditions: Sleep Disorders, Circadian Rhythm, Depression, Genotoxicity, PainView official trial listing → -
Status unknown NCT NCT03219008
Multi-Dimensional Diagnosis,Individualized Therapy,and Management Technique for Major Depressive Disorder:Based on Clinical and Pathological Characteristics
Not yet reported Shanghai Mental Health Center 800 participants Est. completion 2020-12 1 site Stand-aloneOther conditions: Depressive DisorderView official trial listing → -
Completed NCT NCT03230630
Plasma Melatonin AND Mortality After Acute Myocardial Infarction
Chinese PLA General Hospital 732 participants Est. completion 2017-01-01Cardiovascular disease Other conditions: MelatoninView official trial listing → -
Terminated NCT NCT03241004
Does Melatonin Affect Anesthetic MAC (Minimum Alveolar Concentration)?
Not yet reported Englewood Hospital and Medical Center 12 participants Est. completion 2021-07-08 1 siteOther conditions: AnesthesiaView official trial listing → -
Completed NCT NCT03255642
Efficacy and Safety of Melatonin and Clonazepam for IRBD
Not yet reported Kyung Hee University Hospital at Gangdong 34 participants Est. completion 2020-12-01 1 siteOther conditions: REM Sleep Behavior DisorderView official trial listing → -
Status unknown NCT NCT03258294
Effect of Melatonin on Sleep Disturbances in Patients With Parkinson's Disease
Not yet reported KIMJisun 82 participants Est. completion 2018-12-30 Stand-aloneOther conditions: Parkinson's DiseaseView official trial listing → -
Completed NCT NCT03295162
Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsis
Not yet reported, Not yet reported Mohamed Hussein Metwally 55 participants Est. completion 2017-09-01 Stand-aloneOther conditions: Neonatal SepsisView official trial listing → -
Status unknown NCT NCT03303378
Effects of Melatonin on Reperfusion Injury
Not yet reported Chinese PLA General Hospital 190 participants Est. completion 2019-11-01 1 site Stand-aloneOther conditions: Reperfusion Injury, MyocardialView official trial listing → -
Completed NCT NCT03306303
Association Between Plasma Melatonin and No-reflow
Chinese PLA General Hospital 1700 participants Est. completion 2017-10-01Cardiovascular diseaseView official trial listing → -
Completed NCT NCT03313115
Sleep/Wake Protocol Implementation to Improve Sleep Quality in the ICU
University of Utah 685 participants Est. completion 2018-03-14 1 siteOther conditions: Sleep Deprivation, DeliriumView official trial listing → -
Completed NCT NCT03316989
Melatonin Levels and the Relation to Obesity and the Metabolic Syndrome in Children and Adolescents
Sheba Medical Center 20 participants Est. completion 2013-05-30Metabolic syndromeView official trial listing → -
Status unknown NCT NCT03343470
The Circadian Rhythm in CusHing SyndrOme in Active Phase and dUring RemiSsion (TheHOURS)
University of Roma La Sapienza 15 participants Est. completion 2023-12-30 1 siteOther conditions: Cushing SyndromeView official trial listing → -
Status unknown NCT NCT03348982
Examining the Association Between Physical Activity and Sleep Quality in Children With Autism Spectrum Disorder
Not yet reported The Hong Kong Polytechnic University 32 participants Est. completion 2019-06Other conditions: Physical Activity, Sleep Apnea, Autism Spectrum DisorderView official trial listing → -
Completed NCT NCT03364101
The Poweroff Sleep Study
Not yet reported NYU Langone Health 60 participants Est. completion 2018-04-24 1 site Stand-aloneOther conditions: SleepView official trial listing → -
Completed NCT NCT03368352
Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude.
Not yet reported University of California, San Diego 20 participants Est. completion 2018-12-20 1 site Stand-aloneOther conditions: Altitude Hypoxia, Ventilation, Sleep, Oxidative Stress, Neurocognitive DysfunctionView official trial listing → -
Completed NCT NCT03368430
Melatonin as an Adjunctive Therapy for Chronic Periodontitis.
Not yet reported Mansoura University 74 participants Est. completion 2017-09-07 1 site Stand-aloneOther conditions: Periodontal DiseasesView official trial listing → -
Completed NCT NCT03403959
Seasonal Affective Disorder and Visual Impairment
Not yet reported Psychiatric Centre Rigshospitalet 18 participants Est. completion 2020-03-12 1 site Stand-aloneOther conditions: Seasonal Affective Disorder, Visual ImpairmentView official trial listing → -
Status unknown NCT NCT03419767
Insulin Resistance in Patients After Carotid Revascularization
Not yet reported Peking Union Medical College Hospital 60 participants Est. completion 2018-06-01 1 siteOther conditions: Carotid StenosisView official trial listing → -
Completed NCT NCT03432091
Melatonin Receptor Agonist and Peripheral Biological Markers
National Science and Technology Council, Taiwan 40 participants Est. completion 2019-07-31Other conditions: InsomniaView official trial listing → -
Completed NCT NCT03461042
The Study of Combination Use of Melatonin Receptor Agonist for Dose Reduction or Interruptions of Benzodiazepine (BZD) and Non-BZD Hypnotics on Chronic Insomnia
Not yet reported Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan 17 participants Est. completion 2020-03-16 1 siteOther conditions: Chronic InsomniaView official trial listing → -
Completed NCT NCT03464084
Interaction of Melatonin With MTNR1B Genotype on Glucose Control - Study 2
Not yet reported Brigham and Women's Hospital 24 participants Est. completion 2022-07-19 1 siteOther conditions: Glucose, Circadian Rhythm, Melatonin, Genes, LightView official trial listing → -
Completed NCT NCT03475459
Investigation of Arrhythmogenic Effect of NPC-15 (NPC-15-7)
Not yet reported Nobelpharma 12 participants Est. completion 2018-04-29 1 site Stand-aloneOther conditions: Qt Interval, Variation inView official trial listing → -
Completed NCT NCT03478306
Diabetic Retinopathy: Effects of Melatonin Treatment on Visual Functions and Circadian Rhythm
Not yet reported Glostrup University Hospital, Copenhagen 31 participants Est. completion 2021-06-12 1 siteOther conditions: Diabetic Retinopathy, Melatonin, Circadian Dysrhythmia, Circadian Rhythm Sleep Disorder, Unspecified TypeView official trial listing → -
Completed NCT NCT03490825
Aging Program Project Grant 6
Not yet reported Northwestern University 32 participants Est. completion 2024-05-31 1 site Stand-aloneOther conditions: Improving Cardiometabolic Outcomes in Older AdultsView official trial listing → -
Completed NCT NCT03490864
Strengthening Circadian Signals
Not yet reported Northwestern University 43 participants Est. completion 2024-07-31 1 site Stand-aloneOther conditions: Improving Cardiometabolic Outcomes in AdultsView official trial listing → -
Terminated NCT NCT03492736
Effects of Melatonin in Untreated Obstructive Sleep Apnea
Not yet reported Naomi Deacon 1 participants Est. completion 2018-10-01 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT03492970
Melatonin in Adults With SMS
Not yet reported Hôpital le Vinatier 10 participants Est. completion 2019-03-30 1 siteOther conditions: Smith Magenis SyndromeView official trial listing → -
Completed NCT NCT03498131
Melatonin in Patients With Multiple Sclerosis (MS).
Not yet reported Providence Health & Services 30 participants Est. completion 2023-12-11 1 site Stand-aloneOther conditions: Relapsing Remitting Multiple SclerosisView official trial listing → -
Status unknown NCT NCT03500458
Impact of Sleep Extension in Adolescents
Not yet reported University of Colorado, Denver 75 participants Est. completion 2025-05-31 1 site Stand-aloneOther conditions: Insulin Sensitivity, Sleep, Dietary HabitsView official trial listing → -
Completed NCT NCT03505411
The Influence of Melatonin Supplementation in the Group of Persons Performing Competitive Sport.
Not yet reported Nicolaus Copernicus University 81 participants Est. completion 2012-12-31 Stand-aloneOther conditions: Antioxidants, Oxidative Stress, Inflammation, Lipid PeroxidationView official trial listing → -
Completed NCT NCT03514732
Study to Evaluate Improvements of the Quality of Sleep With NOVANUIT® Triple Action in Healthy Volunteers With Sleep Disorders
Not yet reported Sanofi 40 participants Est. completion 2017-07-05 1 site Stand-aloneOther conditions: Sleep Disorder (Healthy Volunteers)View official trial listing → -
Completed NCT NCT03519750
Pharmacokinetics of Intravenous, Rectal, Intravesical, Vaginal, and Transdermal Melatonin in Healthy Female Volunteers
Not yet reported Dennis Bregner Zetner 10 participants Est. completion 2019-02-21 1 site Stand-aloneOther conditions: Melatonin, Pharmacokinetics, SafetyView official trial listing → -
Completed NCT NCT03524937
Prevention of Delirium in Intensive Care by Melatonin
Not yet reported, Not yet reported Assistance Publique - Hôpitaux de Paris 355 participants Est. completion 2021-05-20 1 site Stand-aloneOther conditions: Mechanically Ventilated PatientsView official trial listing → -
Terminated NCT NCT03540485
Safety and Efficacy of Melatonin in Patients With Multiple Progressive Primary Sclerosis
Not yet reported, Not yet reported Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 25 participants Est. completion 2026-02-18 3 sites Stand-aloneOther conditions: Sclerosis, Multiple, Autoimmune Diseases of the Nervous System, Nervous System Diseases, Autoimmune DiseasesView official trial listing → -
Status unknown NCT NCT03557229
Clinical Trial of Antioxidant Therapy in Patients With Septic Shock
Not yet reported American British Cowdray Medical Center 131 participants Est. completion 2022-06 1 site Stand-aloneOther conditions: Oxidative Stress, Septic ShockView official trial listing → -
Completed NCT NCT03563287
Effects of LRYGB on Pharmacokinetics of Nine CYP Probe Drugs
Not yet reported University of Eastern Finland 13 participants Est. completion 2014-12-10 1 site Stand-aloneOther conditions: Obesity, Morbid, Bariatric Surgery CandidateView official trial listing → -
Completed NCT NCT03567395
Honey to Improve Sleep Quality: a Feasibility Study
Not yet reported University of Saskatchewan 20 participants Est. completion 2018-12-15 1 siteOther conditions: Poor Quality SleepView official trial listing → -
Completed NCT NCT03588676
Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude
Not yet reported Robert L. Owens 39 participants Est. completion 2018-12-10 1 site Stand-aloneOther conditions: Intermittent HypoxiaView official trial listing → -
Completed NCT NCT03590197
Effect of Melatonin on Seizure Outcome, Neuronal Damage and Quality of Life in Patients With Generalized Epilepsy
Not yet reported All India Institute of Medical Sciences, Bhubaneswar 104 participants Est. completion 2020-04-12 1 site Stand-aloneOther conditions: Generalized EpilepsyView official trial listing → -
Completed NCT NCT03591341
Melatonin Degradation Rate in Human Milk
Carmel Medical Center 10 participants Est. completion 2018-12-31 1 siteOther conditions: Preterm Infant, LactationView official trial listing → -
Completed NCT NCT03597529
CHOCOlate MeLatonin for AdolescenT MigrainE
Not yet reported Amy Gelfand 84 participants Est. completion 2019-12-01 1 site Stand-aloneOther conditions: MigraineView official trial listing → -
Completed NCT NCT03609086
Melatonin in Pregnancy
University of Aberdeen 15 participants Est. completion 2019-03-30 2 sitesOther conditions: PregnancyView official trial listing → -
Completed NCT NCT03631901
Comparison Between Melatonin and Diazepam for Prevention of Recurrent Simple Febrile Seizures
Not yet reported Tanta University 60 participants Est. completion 2018-09-01 1 siteOther conditions: Febrile SeizuresView official trial listing → -
Status unknown NCT NCT03655184
An Observation Study on Neuropsychology and Serum Melatonin Level in Patients With Medication Overuse Headache
The First Affiliated Hospital with Nanjing Medical University 90 participants Est. completion 2019-06-30 1 siteOther conditions: Medication Overuse HeadacheView official trial listing → -
Completed NCT NCT03656484
New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin
Not yet reported Concordia Dent Srl 50 participants Est. completion 2019-12-20 2 sites Stand-aloneOther conditions: Chronic PeriodontitisView official trial listing → -
Completed NCT NCT03659760
: Association of Melatonin Levels and Light and Noise Isolation in ICU
Not yet reported Diskapi Yildirim Beyazit Education and Research Hospital 41 participants Est. completion 2019-04-25 1 siteOther conditions: Cranial Nerve DiseasesView official trial listing → -
Withdrawn NCT NCT03688464
Treatment of Nighttime Pruritus in Atopic Dermatitis
Not yet reported University of Nebraska Est. completion 2019-02-02Other conditions: Atopic DermatitisView official trial listing → -
Completed NCT NCT03689998
Evaluation of Melatonin Application of Immediate Dental Implant
Not yet reported Cairo University 24 participants Est. completion 2021-05-30 1 site Stand-aloneOther conditions: Immediate Dental ImplantView official trial listing → -
Status unknown NCT NCT03691740
Uterine Contractions Under Blue Light
Not yet reported University of South Florida 30 participants Est. completion 2019-06 1 siteOther conditions: Preterm ContractionsView official trial listing → -
Status unknown NCT NCT03692026
Assessment of Immediate Implant Stability When Adding Mixture of Hyaluronic Acid and Melatonin
Not yet reported Cairo University 24 participants Est. completion 2020-06 Stand-aloneOther conditions: Immediate Dental ImplantView official trial listing → -
Status unknown NCT NCT03708341
Exogenous Melatonin in Intensive Care Unit Chronodisruption
Not yet reported Saint-Joseph University 98 participants Est. completion 2024-03-01 1 site Stand-aloneOther conditions: Sleep Deprivation, Intensive Care PsychosisView official trial listing → -
Completed NCT NCT03715465
The Clinical Utility of Measuring the Circadian Clock in Treatment of Delayed Sleep-Wake Phase Disorder
Not yet reported University of Michigan 44 participants Est. completion 2021-11-05 1 site Stand-aloneOther conditions: Delayed Sleep Phase SyndromeView official trial listing → -
Completed NCT NCT03716583
Melatonin Cream Against Acute Radiation Dermatitis in Patients With Early Breast Cancer
Not yet reported Dennis Bregner Zetner 48 participants Est. completion 2021-01-31 1 site Stand-aloneOther conditions: Radiation Dermatitis, Radiation Dermatitis Acute, Breast CancerView official trial listing → -
Terminated NCT NCT03725267
Melatonin for Renal Protection in Patients Receiving Polymyxin B
Not yet reported Hospital de Clinicas de Porto Alegre 88 participants Est. completion 2021-07-01 2 sites Stand-aloneOther conditions: Acute Kidney Injury, Melatonin, Polymyxin B Adverse ReactionView official trial listing → -
Completed NCT NCT03730194
A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders
Not yet reported University of Nebraska 40 participants Est. completion 2021-11-01 1 site Stand-aloneOther conditions: Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Sleep DisturbanceView official trial listing → -
Completed NCT NCT03732963
Oral Melatonin as Premedication During MAC for Patients Undergoing Loco-regional Chronic Subdural Hematoma Evacuation
Not yet reported Cairo University 40 participants Est. completion 2018-11-07 1 siteOther conditions: Monitored Anaesthesia Care, Loco-regional Chronic Subdural Hematoma EvacuationView official trial listing → -
Status unknown NCT NCT03764020
Trial of Oral Melatonin in Elevated Blood Pressure
Not yet reported Tehran University of Medical Sciences 320 participants Est. completion 2019-12-01 Stand-aloneOther conditions: Elevated Blood PressureView official trial listing → -
Completed NCT NCT03779243
Treatment for Sleep Disturbance in Orthopaedic Trauma Patients
Not yet reported Stanford University 90 participants Est. completion 2021-08-24 1 site Stand-aloneOther conditions: Sleep Disturbance, TraumaView official trial listing → -
Completed NCT NCT03782740
Effect of Melatonin on Reduction of Pelvic Pain
Not yet reported Karolinska Institutet 80 participants Est. completion 2021-06-30 1 site Stand-aloneOther conditions: Dysmenorrhea, EndometriosisView official trial listing → -
Completed NCT NCT03784495
Melatonin Plus Aminoacids for Sarcopenic Elderly
Not yet reported Azienda di Servizi alla Persona di Pavia 159 participants Est. completion 2015-06-01 1 site Stand-aloneOther conditions: SarcopeniaView official trial listing → -
Completed NCT NCT03785158
MIND After Surgery
Not yet reported McMaster University 88 participants Est. completion 2025-07-05 2 sitesOther conditions: Post-operative Delirium, Major Non-cardiac SurgeryView official trial listing → -
Status unknown NCT NCT03788733
The Efficacy of Melatonin in the Burning Mouth Syndrome
Not yet reported Universidad de Murcia 80 participants Est. completion 2019-12-14 1 site Stand-aloneOther conditions: Sleep Disorders, Circadian RhythmView official trial listing → -
Completed NCT NCT03788993
Testing the Effectiveness of an Evening Blue-depleted Light Environment in an Acute Psychiatric Ward
Not yet reported St. Olavs Hospital 475 participants Est. completion 2021-12-01 1 site Stand-aloneOther conditions: Mental DisorderView official trial listing → -
Status unknown NCT NCT03804177
The Effect Of Hyaluronic Acid And Melatonin With Systemic Administration of Vitamin C On Implant Stability After Immediate Implant in Anterior Region
Not yet reported Cairo University 24 participants Est. completion 2022-04-30 Stand-aloneOther conditions: Immediate Dental ImplantView official trial listing → -
Status unknown NCT NCT03806816
Use of Melatonin for Neuroprotection in Asphyxiated Newborns
Not yet reported University Hospital of Ferrara 100 participants Est. completion 2022-12-31 6 sites Stand-aloneOther conditions: Hypoxic-Ischemic Encephalopathy, Cell Damage, Asphyxia PerinatalView official trial listing → -
Completed NCT NCT03826563
Melatonin Effects on Sleep and Circadian Rhythm in Youth and Young Adults With At-risk Symptoms
Not yet reported Children's Hospital of Philadelphia 21 participants Est. completion 2023-04-07 1 site Stand-aloneOther conditions: Psychosis, SleepView official trial listing → -
Completed NCT NCT03831165
Melatonin Effects on Genital Herpes in Brazilian Women
Not yet reported University of Sao Paulo General Hospital 90 participants Est. completion 2021-12-28 2 sites Stand-aloneOther conditions: Genital HerpesView official trial listing → -
Completed NCT NCT03833570
Melatonin for Prevention of Radiation Induced Oral Mucositis
Not yet reported Hams Hamed Abdelrahman 40 participants Est. completion 2018-12-01 1 site Stand-aloneOther conditions: Oral Mucositis (Ulcerative) Due to RadiationView official trial listing → -
Withdrawn NCT NCT03843008
Melatonin in Acute Stroke
Not yet reported University of Florida Est. completion 2023-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT03848533
Effect of Melatonin and Metformin on Glycemic Control Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes
Not yet reported University of Guadalajara 42 participants Est. completion 2021-12 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT03859934
Metabolic Effects of Melatonin Treatment
Not yet reported University of Aarhus 17 participants Est. completion 2021-08-18 1 siteType 2 diabetes Other conditions: Metabolic Disease, Insulin Sensitivity, Glucose Metabolism Disorders (Including Diabetes Mellitus), Blood Pressure, InflammationView official trial listing → -
Withdrawn NCT NCT03879707
Improving Sleep Quality After Total Joint Arthroplasty ( TJA)
Not yet reported Stanford University Est. completion 2028-06 1 site Stand-aloneOther conditions: Pain After TJAView official trial listing → -
Completed NCT NCT03885258
Melatonin Replacement Therapy in Pinealectomized Patients
Not yet reported University of Sao Paulo 5 participants Est. completion 2019-02-28 1 site Stand-aloneOther conditions: Pineal TumorView official trial listing → -
Status unknown NCT NCT03894683
Effect of Melatonin on Cardiovascular and Muscle Mass and Function in Patients With Heart Failure
Not yet reported Isfahan University of Medical Sciences 90 participants Est. completion 2020-12 1 site Stand-aloneHeart failureView official trial listing → -
Status unknown NCT NCT03897101
Inflammation and Metabolic Acidosis at Birth (AGAIN: AutophaGy AcIdosis Newborn)
University Hospital of Ferrara 150 participants Est. completion 2020-12-31 2 sitesOther conditions: Neonatal Encephalopathy, Cell Damage, Metabolic Acidosis, InflammationView official trial listing → -
Completed NCT NCT03945955
Melatonin and DNA Damage Study
Not yet reported University of British Columbia 40 participants Est. completion 2023-11-01 1 site Stand-aloneOther conditions: Sleep Quality, DNA Damage Repair Deficiency, Oxidative StressView official trial listing → -
Completed NCT NCT03951025
Study of the Bioavailability of a Food Supplement Rich in Melatonin Administered Sublingually and Orally (MELATONIN)
Not yet reported Technological Centre of Nutrition and Health, Spain 13 participants Est. completion 2019-08-07 1 site Stand-aloneOther conditions: Biological AvailabilityView official trial listing → -
Completed NCT NCT03953066
Colostral Milk and Blood IL-6 Levels in Types of Labour
Not yet reported Samsun Education and Research Hospital 90 participants Est. completion 2019-08-20 1 siteOther conditions: Indications for Care in Pregnancy; Labor; and DeliveryView official trial listing → -
Status unknown NCT NCT03956420
Enhanced Recovery After Surgery (ERAS) in Coronary Artery Bypass Graft / Off Pump Coronary Artery Bypass (CABG/OPCAB)
Silesian University of Medicine 100 participants Est. completion 2021-05 1 siteCardiovascular disease Other conditions: Coronary StenosisView official trial listing → -
Status unknown NCT NCT03966235
Melatonin on Coronary Artery Calcification
Not yet reported Chinese PLA General Hospital 74 participants Est. completion 2021-06-01 1 site Stand-aloneOther conditions: Coronary Artery CalcificationView official trial listing → -
Status unknown NCT NCT03966950
Use of Melatonin for Preventing POCD in Transurethral Prostate Resection Under Spinal Anesthesia
Not yet reported University of Sao Paulo 104 participants Est. completion 2021-11-26 1 site Stand-aloneOther conditions: Melatonin, Cognitive Dysfunction, Postoperative Complications, Prostate HyperplasiaView official trial listing → -
Completed NCT NCT03967366
Melatonin and Coronary Artery Calcification
Chinese PLA General Hospital 574 participants Est. completion 2019-04-30 1 siteOther conditions: Coronary Artery CalcificationView official trial listing → -
Completed NCT NCT03968939
Total Joint Arthroplasty and Sleep
Not yet reported James A. Keeney 55 participants Est. completion 2022-05-22 1 siteOther conditions: Primary Total Hip Arthroplasty, Primary Total Knee ArthroplastyView official trial listing → -
Suspended NCT NCT03995004
The Effect of Melatonin on Postoperative Pain Reduction After Orthognathic Surgery
Not yet reported The University of Hong Kong 87 participants Est. completion 2024-09 1 site Stand-aloneOther conditions: Effect of DrugsView official trial listing → -
Completed NCT NCT04005222
Effects of Selenium and Melatonin on Ocular Ischemic Syndrome
Not yet reported Beytepe Murat Erdi Eker State Hospital 28 participants Est. completion 2016-11Other conditions: Anterior Segment Ischemia (Diagnosis)View official trial listing → -
Completed NCT NCT04013464
Effects of Escitalopram on the Sleep EEG Power in Patients With Major Depressive Disorder
Not yet reported Peking University Sixth Hospital 31 participants Est. completion 2018-12-30Other conditions: Depressive Disorder, MajorView official trial listing → -
Completed NCT NCT04019899
Myo-inositol and Vitamin D3 During IVF
Not yet reported Lo.Li.Pharma s.r.l 120 participants Est. completion 2019-05-31 1 site Stand-aloneOther conditions: Female InfertilityView official trial listing → -
Completed NCT NCT04020848
Observe Alternating Hemiplegia of Childhood (OBSERV-AHC) Study
Hospices Civils de Lyon 34 participants Est. completion 2022-11-17 1 siteOther conditions: Alternating HemiplegiaView official trial listing → -
Completed NCT NCT04034771
The Effect of Melatonin Administration on Sedation Level as Adjuvant to Propofol
Not yet reported Cairo University 38 participants Est. completion 2018-04-05 1 site Stand-aloneOther conditions: TBI (Traumatic Brain Injury)View official trial listing → -
Completed NCT NCT04035889
Melatonin for Sleep in MS
Not yet reported University of California, San Francisco 30 participants Est. completion 2020-11-17 1 site Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Status unknown NCT NCT04063332
Functionality of Endogenous Biological Clock in Sepsis
University of Athens 60 participants Est. completion 2024-06 2 sitesOther conditions: Circadian Rhythm Disorders, SepsisView official trial listing → -
Completed NCT NCT04067791
A Study to Investigate the Pharmacokinetics of Prolonged-release Melatonin Compared to Standard, Immediate-release Melatonin in Healthy Adults
Not yet reported Pharmavite LLC 18 participants Est. completion 2019-08-27 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT04093271
Investigating the Efficacy of Rest-ZZZ Formula in Healthy Participants With Difficulty Falling Asleep or Staying a Sleep
Not yet reported LifeSeasons Inc. 27 participants Est. completion 2019-12-23 1 site Stand-aloneOther conditions: Sleep, HealthyView official trial listing → -
Terminated NCT NCT04105218
Exercise, Sleep Quality and Nocturnal Fat Oxidation in Metabolic Syndrome
Not yet reported University of Colorado, Denver 12 participants Est. completion 2021-03-02 1 site Stand-aloneMetabolic syndromePrediabetes Other conditions: Hypertension, Obesity, HyperlipidemiasView official trial listing → -
Status unknown NCT NCT04122599
Melatonin for Prevention of Post Stroke Delirium
Not yet reported, Not yet reported University Hospital Tuebingen 2000 participants Est. completion 2019-12-31 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT04137627
Melatonin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response in Locally Advanced Oral Squamous Cell Carcinoma
Not yet reported Universitas Indonesia 50 participants Est. completion 2018-12-18 1 site Stand-aloneOther conditions: Oral Squamous Cell Carcinoma, Neoadjuvant ChemotherapyView official trial listing → -
Status unknown NCT NCT04187807
Efficacy of the Administration of Melatonin 5mg in the Prevention of Delirium in Older Adults Hospitalized in the Emergency Department
Not yet reported Universidad Autonoma de San Luis Potosí 145 participants Est. completion 2020-05 1 site Stand-aloneOther conditions: Delirium in Old AgeView official trial listing → -
Completed NCT NCT04189666
Rivastigmine Patch Compared to Melatonin Patch in Prevention of Postoperative Delirium
Not yet reported, Not yet reported Ain Shams University 180 participants Est. completion 2020-05-01 1 siteOther conditions: DeliriumView official trial listing → -
Status unknown NCT NCT04193501
Frequency of Sleep Abnormalities in Patients With Irritable Bowel Syndrome and Effect of Pharmacological Intervention
Not yet reported Sanjay Gandhi Postgraduate Institute of Medical Sciences 194 participants Est. completion 2022-02 2 sites Stand-aloneOther conditions: Irritable Bowel SyndromeView official trial listing → -
Status unknown NCT NCT04229719
Effect of Topical Melatonin Application on Dental Implant Osseointegration and Marginal Bone Level
Not yet reported University of Baghdad 10 participants Est. completion 2020-11-01 1 site Stand-aloneOther conditions: Alveolar Bone LossView official trial listing → -
Status unknown NCT NCT04230707
Endogenous Melatonin Levels on Anxiety in Living Liver Donors
Inonu University 60 participants Est. completion 2020-03-01 1 siteOther conditions: Liver Transplantation, Anxiety, MelatoninView official trial listing → -
Completed NCT NCT04233112
Melatonin and Osteogenic Loading on Osteopenia
Not yet reported Duquesne University 27 participants Est. completion 2024-08-08 2 sites Stand-aloneOther conditions: OsteopeniaView official trial listing → -
Withdrawn NCT NCT04233502
Efficacy and Safety of Slenyto for Insomnia in Children With ASD
Not yet reported Neurim Pharmaceuticals Ltd. Est. completion 2022-12 Stand-aloneOther conditions: Autism Spectrum DisorderView official trial listing → -
Completed NCT NCT04235673
Oral Melatonin as Neuroprotectant in Preterm Infants
Not yet reported Francesca Garofoli 60 participants Est. completion 2022-10-11 4 sites Stand-aloneOther conditions: Malondialdehyde, MelatoninView official trial listing → -
Active, not recruiting NCT NCT04247646
SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty
Not yet reported Scripps Health 120 participants Est. completion 2028-12-31 1 siteOther conditions: Opioid Use, Pain, Postoperative, Sleep, DeliriumView official trial listing → -
Status unknown NCT NCT04251845
Evaluation of Effect of Topical Melatonin in Treatment of Oral Leukoplakia
Not yet reported Postgraduate Institute of Dental Sciences Rohtak 66 participants Est. completion 2020-09-30 1 siteOther conditions: Oral LeukoplakiaView official trial listing → -
Status unknown NCT NCT04278456
Postpartum Depression
Erzincan University 300 participants Est. completion 2020-07-21 1 siteOther conditions: Postpartum Depression, MelatoninView official trial listing → -
Status unknown NCT NCT04278677
Sleep Quality and Pain Medication Use Following Arthroscopic Rotator Cuff Repair
Not yet reported Rothman Institute Orthopaedics 80 participants Est. completion 2021-03 1 siteOther conditions: Sleep DisturbanceView official trial listing → -
Withdrawn NCT NCT04287543
Melatonin on Clock Genes in Parkinson's Disease
Not yet reported, Not yet reported Instituto Mexicano del Seguro Social Est. completion 2022-08 1 site Stand-aloneOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT04304807
Effect of Melatonin on Feeding Intolerance and Incidence of Necrotizing Enterocolitis in Preterm Infants
Not yet reported Ain Shams University 90 participants Est. completion 2019-12-31 1 site Stand-aloneOther conditions: Preterm Infant, Feeding Intolerance, Necrotizing EnterocolitisView official trial listing → -
Status unknown NCT NCT04318067
Melatonin in ADHD and Sleep Problems
Not yet reported Allan Hvolby 80 participants Est. completion 2024-11 1 site Stand-aloneOther conditions: Attention Deficit Hyperactivity Disorder, Sleep DisorderView official trial listing → -
Status unknown NCT NCT04325191
Melatonin and Salt on Blood Vessel Function
Not yet reported University of Delaware 15 participants Est. completion 2022-09-30 1 site Stand-aloneOther conditions: Cardiovascular Risk FactorView official trial listing → -
Completed NCT NCT04335968
Melatonin for Prevention of Postoperative Delirium After Lower Limb Fracture Surgery in Elderly Patients
Not yet reported Assistance Publique - Hôpitaux de Paris 357 participants Est. completion 2025-04-18 1 site Stand-aloneOther conditions: Orthopedic SurgeryView official trial listing → -
Completed NCT NCT04336566
Renal Effects of Melatonin Trial in Chronic Kidney Disease
Not yet reported University of Oklahoma 31 participants Est. completion 2020-05-13 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT04350567
Sleep/Wake Cycle and Depression: An Imaging and Treatment Study
Not yet reported Stony Brook University 61 participants Est. completion 2025-05-31 1 site Stand-aloneOther conditions: Depression; Major Depressive DisorderView official trial listing → -
Completed NCT NCT04352062
Melatonin Supplementation in Postmenopausal Women With H. Pylori-associated Dyspepsia
Not yet reported Medical University of Lodz 152 participants Est. completion 2018-10-26 1 site Stand-aloneOther conditions: Melatonin DeficiencyView official trial listing → -
Completed NCT NCT04353128
Efficacy of Melatonin in the Prophylaxis of Coronavirus Disease 2019 (COVID-19) Among Healthcare Workers.
Not yet reported, Not yet reported Instituto de Investigación Hospital Universitario La Paz 450 participants Est. completion 2020-12-01 1 site Stand-aloneOther conditions: Covid19, SARS-CoV 2, Coronavirus InfectionView official trial listing → -
Status unknown NCT NCT04364347
Chemotherapy-induced Circadian Rhythm Disruption
Seoul National University Hospital 27 participants Est. completion 2023-02 1 siteOther conditions: Breast NeoplasmsView official trial listing → -
Completed NCT NCT04392063
Melatonin for Cerebral Palsy Children's Sleep and Health
Not yet reported Ain Shams University 40 participants Est. completion 2018-09 1 siteOther conditions: Cerebral Palsy, Melatonin, Growth, Children, OnlyView official trial listing → -
Status unknown NCT NCT04409522
Evaluation of Therapeutic Effects of Melatonin by Inhibition of NLRP3 Inflammasome in COVID19 Patients
Not yet reported Mohammad Sadegh Bagheri Baghdasht 55 participants Est. completion 2020-09-25 1 site Stand-aloneOther conditions: COVID-19View official trial listing → -
Completed NCT NCT04420611
Use of Endogenous Melatonin and 6-hydroxymelatonin as Biomarkers for CYP1A2
Youssef Daali 12 participants Est. completion 2020-12-30 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT04421339
Melatonin for Huntington's Disease (HD) Gene Carriers With HD Related Sleep Disturbance - a Pilot Study
Not yet reported The University of Texas Health Science Center, Houston 15 participants Est. completion 2022-09-16 1 site Stand-aloneOther conditions: Huntington DiseaseView official trial listing → -
Completed NCT NCT04424875
The Effect of Melatonin Application Following Removal of Impacted Third Molar
Not yet reported Fayoum University 38 participants Est. completion 2021-05-01 1 site Stand-aloneOther conditions: Impacted Third Molar ToothView official trial listing → -
Status unknown NCT NCT04470297
Melatonin Agonist on Hospitalized Patients With Confirmed or Suspected COVID-19
Not yet reported Associação Fundo de Incentivo à Pesquisa 100 participants Est. completion 2021-03Other conditions: Covid19, Lung InjuryView official trial listing → -
Terminated NCT NCT04474483
Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19
Not yet reported State University of New York at Buffalo 8 participants Est. completion 2022-07-22 1 site Stand-aloneOther conditions: COVID-19View official trial listing → -
Completed NCT NCT04483596
Melatonin to Decrease the Incidence of Postoperative Delirium in Geriatric Patients
Cairo University 100 participants Est. completion 2020-12-03 1 siteOther conditions: Postoperative DeliriumView official trial listing → -
Completed NCT NCT04505800
Tryptophan Supplementation to Improve Night Shift Workers' Health
Not yet reported National Yang Ming Chiao Tung University 30 participants Est. completion 2020-12-31 1 siteOther conditions: Sleep, Mood, Burnout, Melatonin Deficiency, Cortisol DeficiencyView official trial listing → -
Status unknown NCT NCT04522960
Melatonin in Alzheimer's Disease: Effect on Disease Progression and Epileptiform Activity.
Not yet reported Universitair Ziekenhuis Brussel 60 participants Est. completion 2023-07 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT04530097
Radiofrequency Ablation Combined With Melatonin in the Treatment of Stage IA NSCLC
Not yet reported Shanghai 10th People's Hospital 260 participants Est. completion 2022-09-30 1 site Stand-aloneOther conditions: NSCLC and TheropyView official trial listing → -
Completed NCT NCT04530539
The Effect of Melatonin and Vitamin C on COVID-19
Not yet reported Lancaster General Hospital 122 participants Est. completion 2022-08-11 1 site Stand-aloneOther conditions: Covid19, SARS-CoV InfectionView official trial listing → -
Withdrawn NCT NCT04531748
Selective Estrogen Modulation and Melatonin in Early COVID-19
Not yet reported Reena Mehra, MD Est. completion 2022-09Other conditions: Covid19View official trial listing → -
Completed NCT NCT04568863
Efficacy of Intravenous Melatonin on Mortality in Adult Patients Admitted to the Intensive Care Unit With COVID-19
Not yet reported Pharmamel S.L. 18 participants Est. completion 2020-11-30 1 site Stand-aloneOther conditions: COVID-19, SARS-CoV 2, Coronavirus InfectionView official trial listing → -
Completed NCT NCT04570254
Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19
Not yet reported Unidad Temporal COVID-19 en Centro Citibanamex 110 participants Est. completion 2020-12-01 1 site Stand-aloneOther conditions: Pneumonia, Viral, Covid19, ARDS, Oxidative StressView official trial listing → -
Completed NCT NCT04574141
Kinetic of Melatonin Subsequent to the Consumption of Melatonin-rich Food Supplements
Not yet reported PiLeJe 14 participants Est. completion 2020-10-05 1 site Stand-aloneOther conditions: Melatonin BioavailabilityView official trial listing → -
Status unknown NCT NCT04588220
Melatonin, Soluble Urokinase-type Plasminogen Activator Receptor, and Orosomucoid 2 Levels in PPROM
Cengiz Gokcek Women's and Children's Hospital 88 participants Est. completion 2021-12-30 1 siteOther conditions: Preterm Premature Rupture of MembranesView official trial listing → -
Status unknown NCT NCT04590742
Randomized Trial Investigating Melatonin Supplementation vs Placebo on Sleep Disturbance Following Total Joint Arthroplasty
Not yet reported Rothman Institute Orthopaedics 154 participants Est. completion 2021-11-30 1 siteOther conditions: Sleep Disturbance, Total Joint ArthroplastyView official trial listing → -
Completed NCT NCT04625179
Melatonin and Hyaluronic Acid in Maxillary Sinus Augmentation
Not yet reported Hams Hamed Abdelrahman 16 participants Est. completion 2020-12-07 1 site Stand-aloneOther conditions: Edentulous; Alveolar Process, AtrophyView official trial listing → -
Not yet recruiting NCT NCT04631341
Melatonin and Risk Of Cardiovascular Events And Malignant Tumors In The Elderly
Not yet reported RenJi Hospital 10000 participants Est. completion 2026-12-31 Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT04642313
Comparison of Mg Vs. K Supplementation on Insomnia in Diabetics
Not yet reported University of Lahore 320 participants Est. completion 2022-04-26 2 sitesOther conditions: Focus of Study is on Insomnia Among Diabetic PatientsView official trial listing → -
Completed NCT NCT04665453
Dexmedetomidine and Melatonin for Sleep Induction for EEG in Children
Not yet reported University Medical Centre Ljubljana 150 participants Est. completion 2022-10-01 1 site Stand-aloneOther conditions: Electroencephalography, Child, Dexmedetomidine, Melatonin, Sleep, EpilepsyView official trial listing → -
Completed NCT NCT04670393
Antioxidant Supplement Associated With Oral Probiotics in Patients With PCOS in IVF
Not yet reported Fertypharm 20 participants Est. completion 2025-01-23 1 site Stand-aloneOther conditions: Infertility, Female, Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04684199
Melatonin in Pediatric FD Population
Not yet reported Children's Mercy Hospital Kansas City 14 participants Est. completion 2015-04 1 siteOther conditions: DyspepsiaView official trial listing → -
Completed NCT NCT04690504
Validation of Circadian Biomarkers in Patients With Sleep Disorders
Brigham and Women's Hospital 50 participants Est. completion 2024-07-01 1 siteOther conditions: Sleep Disorders, Circadian Rhythm, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder, Advanced Sleep Phase Syndrome (ASPS), Delayed Sleep Phase Syndrome, Sleep Wake Disorders, Sleep DisorderView official trial listing → -
Completed NCT NCT04721613
Circadian Melatonin Rhythms in Critically Ill Patients With Delirium
University Hospital, Basel, Switzerland 60 participants Est. completion 2023-05-25 1 siteOther conditions: ICU DeliriumView official trial listing → -
Completed NCT NCT04724668
The Role of the Circadian System in Binge Eating Disorder
Not yet reported University of Cincinnati 84 participants Est. completion 2025-05-30 1 siteOther conditions: Binge-Eating Disorder, Circadian Rhythm DisordersView official trial listing → -
Status unknown NCT NCT04731974
Acute Concussion and Melatonin
Not yet reported Children's National Research Institute 254 participants Est. completion 2024-06-30 1 siteOther conditions: Concussion, Mild, Concussion, Brain, Pediatric ALLView official trial listing → -
Completed NCT NCT04751019
The Use of Amber Glasses in Improving Sleep
Not yet reported Surrey and Borders Partnership NHS Foundation Trust 15 participants Est. completion 2020-01-31 1 siteOther conditions: Sleep Disturbance, InsomniaView official trial listing → -
Withdrawn NCT NCT04784754
Dose-Ranging Study to Assess the Safety and Efficacy of Melatonin in Outpatients Infected With COVID-19
Not yet reported State University of New York at Buffalo Est. completion 2022-12-31 1 site Stand-aloneOther conditions: COVID-19View official trial listing → -
Completed NCT NCT04785183
Antioxidant Effects of Melatonin in Preterm
Not yet reported Azienda Ospedaliera Universitaria Policlinico "G. Martino" 50 participants Est. completion 2020-09-01 1 site Stand-aloneOther conditions: Newborn Morbidity, Oxidative Stress, Pre-Term, Melatonin DeficiencyView official trial listing → -
Status unknown NCT NCT04788979
The Adjunctive Use of Melatonin Therapy in the Treatment of Obese Periodontitis Patients (Clinical and Immunological Study).
Not yet reported, Not yet reported University of Baghdad 80 participants Est. completion 2022-02 1 siteOther conditions: Periodontal DiseasesView official trial listing → -
Completed NCT NCT04791943
Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery
Not yet reported Montefiore Medical Center 60 participants Est. completion 2025-10-20 1 site Stand-aloneOther conditions: Pain, Postoperative, Narcotic UseView official trial listing → -
Completed NCT NCT04795336
Melatonin Use After Primary Total Joint Arthroplasty
Not yet reported NYU Langone Health 294 participants Est. completion 2024-04-18 1 siteOther conditions: Osteo Arthritis KneeView official trial listing → -
Status unknown NCT NCT04802785
The Impact of Air Travel on Passenger Cognitive Functions
Not yet reported, Not yet reported Dinara Zhumanbayeva 50 participants Est. completion 2022-05Other conditions: Air TravelView official trial listing → -
Completed NCT NCT04810975
Strength Training Effects on Musculoskeletal Health
Not yet reported Duquesne University 56 participants Est. completion 2023-11-25 1 siteOther conditions: Musculoskeletal DiseasesView official trial listing → -
Active, not recruiting NCT NCT04831398
The Effects of Acute Melatonin Supplementation on Cardiovascular Responses to Sympathetic Activation
Not yet reported University of Oklahoma 100 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT04864509
The Effects of Melatonin Treatment on Bone, Marrow, Sleep and Blood Pressure
Not yet reported University of Aarhus 40 participants Est. completion 2024-06-01Other conditions: Osteoporosis, PostmenopausalView official trial listing → -
Completed NCT NCT04868539
Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep Restriction
Not yet reported Brigham and Women's Hospital 14 participants Est. completion 2024-05-30 1 siteOther conditions: Glucose Intolerance, Sleep Deprivation, SleepView official trial listing → -
Completed NCT NCT04872712
Comparing Press and Filiform Needle Acupuncture Effectiveness for Improving Insomnia in COVID-19 Healthcare Workers
Not yet reported Universitas Indonesia 34 participants Est. completion 2021-10-31 1 siteOther conditions: InsomniaView official trial listing → -
Completed NCT NCT04878198
Treatment of Sleep Disturbance in Children With ASD
Not yet reported Education University of Hong Kong 62 participants Est. completion 2023-12-30 1 site Stand-aloneOther conditions: Physical Exercise, Sleep Disturbance, Autism Spectrum Disorder, Melatonin DeficiencyView official trial listing → -
Completed NCT NCT04908605
Emergence Agitation After Nasal Surgery: a Randomized Controlled Comparison Between Melatonin and Mirtazapine
Not yet reported Ain Shams University 165 participants Est. completion 2022-03-31 1 siteOther conditions: AgitationView official trial listing → -
Completed NCT NCT04932096
Sleep Management And Recovery After Traumatic Brain Injury in Kids: Pilot Intervention of Melatonin
Not yet reported Oregon Health and Science University 21 participants Est. completion 2025-03-01 1 site Stand-aloneOther conditions: Traumatic Brain Injury, Critical Illness, SleepView official trial listing → -
Completed NCT NCT04934436
The Effect of Nursing Care on Circadian Rhythm
Not yet reported Sakarya University 44 participants Est. completion 2023-02-01 1 site Stand-aloneOther conditions: Circadian Rhythm, Chronobiology Disorders, Biological Clock Disturbance, Nursing Care, Sleep QualityView official trial listing → -
Status unknown NCT NCT04953754
Melatonin and Vaccine Response, Immunity, and Chronobiology Study
Not yet reported Walter Reed National Military Medical Center 200 participants Est. completion 2025-06 1 site Stand-aloneOther conditions: Vaccine Response, Sleep, Circadian Rhythm DisordersView official trial listing → -
Completed NCT NCT04959825
The Role of Preoperative Melatonin in Reducing the Inhaled Isoflurane Requirements in Open Nephrectomy
Not yet reported Cairo University 30 participants Est. completion 2022-05-15 1 siteOther conditions: Postoperative PainView official trial listing → -
Status unknown NCT NCT04995263
A Multicomponent Intervention for Prevention and Treatment of Sleep Disturbances in a Psychiatric Intensive Care Unit
Not yet reported Pontificia Universidad Catolica de Chile 120 participants Est. completion 2023-08-01 1 site Stand-aloneOther conditions: DyssomniasView official trial listing → -
Completed NCT NCT05033639
Efficacy Of Oral Melatonin To Prevent Necrotizing Enterocolitis
Not yet reported, Not yet reported Ilocos Training and Regional Medical Center 100 participants Est. completion 2021-12-31 1 site Stand-aloneOther conditions: Necrotizing EnterocolitisView official trial listing → -
Status unknown NCT NCT05034809
Effectiveness Of High Dose Melatonin As Adjunctive Therapy For Dengue Fever With Warning Signs
Not yet reported Ilocos Training and Regional Medical Center 140 participants Est. completion 2022-10-30 Stand-aloneOther conditions: Dengue Fever With Warning SignsView official trial listing → -
Status unknown NCT NCT05042700
The Effect of Melatonin in Patients With Low Anterior Resection Syndrome
Not yet reported Ismail Gögenur 21 participants Est. completion 2023-12 1 site Stand-aloneOther conditions: Low Anterior Resection SyndromeView official trial listing → -
Status unknown NCT NCT05045937
Observational Study on the Use of Ivermectin as an Outpatient Treatment Option for COVID-19
Patrick Robinson 1000 participants Est. completion 2024-05-01 1 siteOther conditions: Covid19, COVID-19 Pneumonia, COVID-19 Respiratory Infection, COVID-19 Acute BronchitisView official trial listing → -
Status unknown NCT NCT05122130
Effect of Melatonin on Palatal Wound Healing (Randomized Controlled Clinical Trial)
Not yet reported Salma Nabil 26 participants Est. completion 2022-12-20 1 site Stand-aloneOther conditions: Wound HealView official trial listing → -
Completed NCT NCT05141344
Effect of Oral Melatonin on Postoperative Analgesia After Thoracotomy in Infants
Not yet reported Cairo University 50 participants Est. completion 2022-06-10 1 siteOther conditions: Postoperative PainView official trial listing → -
Completed NCT NCT05221151
Melatonin vs Pregabalin for Anxiolysis and Sedation
Not yet reported Menoufia University 78 participants Est. completion 2022-10-02 1 siteOther conditions: AnxietyView official trial listing → -
Completed NCT NCT05223010
Melatonin for Pediatric Emergence Agitation
Not yet reported Menoufia University 117 participants Est. completion 2022-12-03 1 siteOther conditions: Emergence AgitationView official trial listing → -
Status unknown NCT NCT05224167
Melatonin Versus Hydroxizin for Pre Operative Anxiety in Elderly Patients With Hip Fracture
Not yet reported Mongi Slim Hospital 50 participants Est. completion 2022-07-30Other conditions: Preoperative AnxietyView official trial listing → -
Completed NCT NCT05230706
Light/Dark Cycle Promotes Weight Gain in Preterm Infants
Not yet reported Universidad Nacional Autonoma de Mexico 300 participants Est. completion 2020-01-31Other conditions: Preterm InfantsView official trial listing → -
Status unknown NCT NCT05236504
Effects of a Novel Supplement on Sleep, Metabolism, Body Composition and Performance
Not yet reported Bettery S.A. 35 participants Est. completion 2022-07-30 1 site Stand-aloneOther conditions: Sleep Hygiene, Sleep DisturbanceView official trial listing → -
Completed NCT NCT05236907
The Efficacy of Oral Melatonin in Preventing Postoperative Delirium for Patients Undergoing Orthopedic Surgery Under General Anesthesia
Not yet reported University of Baghdad 36 participants Est. completion 2020-11-01 2 sites Stand-aloneOther conditions: Delirium, Anesthesia Emergence, DeliriumView official trial listing → -
Status unknown NCT NCT05256173
Clinical Study on the Effect of Improving Sleep Quality on Cognitive Function in Patients With Epilepsy
Not yet reported Xijing Hospital 100 participants Est. completion 2022-11 1 site Stand-aloneOther conditions: Epilepsy,CognitionView official trial listing → -
Status unknown NCT NCT05257291
Study MIPAE - Melatonin and Essential Arterial Hypertension
Not yet reported Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 23 participants Est. completion 2024-08 1 siteOther conditions: Essential HypertensionView official trial listing → -
Status unknown NCT NCT05285124
HD-tDCS Combined With Circadian Rhythm Reconstruction and Micro Expression Changes on Consciousness Recovery in Patients With Chronic Disturbance of Consciousness
Not yet reported First Affiliated Hospital of Zhejiang University 90 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Disorder of ConsciousnessView official trial listing → -
Status unknown NCT NCT05298657
The Angiotensin-Melatonin Axis in Poor and Hyper Responders for IVF Treatment
Fatima College of Health Sciences 200 participants Est. completion 2024-08-31 1 siteOther conditions: Poor Response to Ovulation Induction, PCOS, Endometriosis, Infertility, FemaleView official trial listing → -
Completed NCT NCT05300594
Effect of Audistim® Day/Night on Hearing Comfort and Patient Quality of Life of Patients With Chronic Tinnitus.
Not yet reported CEN Biotech 110 participants Est. completion 2023-06-05 1 site Stand-aloneOther conditions: TinnitusView official trial listing → -
Terminated NCT NCT05307770
Extended-Release Melatonin in Patients With Rapid Eye Movement Sleep Behavior Disorder
Not yet reported Mayo Clinic 25 participants Est. completion 2024-02-01 1 site Stand-aloneOther conditions: Rapid Eye Movement Sleep Behavior Disorder, Parkinson DiseaseView official trial listing → -
Completed NCT NCT05309681
Salivary Melatonin Levels and Sleep Quality in Patients With Burning Mouth Syndrome
University of Zagreb 45 participants Est. completion 2021-12-15 1 siteOther conditions: Burning Mouth Syndrome, MelatoninView official trial listing → -
Completed NCT NCT05318144
Melatonin Levels on COVID-19 Positive Pregnant Women
Nazan Yurtcu MD 228 participants Est. completion 2022-02-01 1 siteOther conditions: COVID-19 Acute Respiratory Distress Syndrome, Pregnancy Related, Pregnancy ComplicationsView official trial listing → -
Completed NCT NCT05319301
Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study)
Not yet reported Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 40 participants Est. completion 2023-11-01 1 site Stand-aloneOther conditions: Oxytocin Deficiency, Hypopituitarism, Hypothalamic Obesity, Pituitary Dysfunction, Central Diabetes Insipidus, Social IsolationView official trial listing → -
Completed NCT NCT05324267
Determinants of Sleep Quality in Spanish Population (SSQD Study)
University of Salamanca 500 participants Est. completion 2024-08-31 1 siteOther conditions: Sleep QualityView official trial listing → -
Completed NCT NCT05332717
TKA Melatonin and Sleep Quality
Not yet reported Hospital for Special Surgery, New York 176 participants Est. completion 2022-04-30 1 site Stand-aloneOther conditions: Arthroplasty, Replacement, Knee, Sleep Initiation and Maintenance DisordersView official trial listing → -
Completed NCT NCT05349188
Feasibility Study of Personalized Trials to Improve Sleep Quality
Not yet reported Northwell Health 60 participants Est. completion 2023-05-22 1 site Stand-aloneOther conditions: Sleep DisturbanceView official trial listing → -
Completed NCT NCT05368909
Clinical Study to Assess a Dietary Supplement on Sleep Health and Quality
Not yet reported 4Life Research, LLC 30 participants Est. completion 2022-05-31 1 site Stand-aloneOther conditions: Sleep Quality, Sleep HealthView official trial listing → -
Status unknown NCT NCT05372874
Treatment of Hepatitis c by Using Direct-acting Antiviral
Tanta University 50 participants Est. completion 2022-07-30Other conditions: Hepatitis CView official trial listing → -
Completed NCT NCT05378932
Impact of Dysregulation of Core Body Temperature on Sleep in Patients With Hypohidrotic Ectodermal Dysplasia
Not yet reported Assistance Publique - Hôpitaux de Paris 22 participants Est. completion 2024-01-16 1 site Stand-aloneOther conditions: Hypohidrotic Ectodermal DysplasiaView official trial listing → -
Status unknown NCT NCT05382923
Facilitating Adjustment to Simulated Jet Lag
Not yet reported University of Arizona 36 participants Est. completion 2023-05 1 site Stand-aloneOther conditions: Circadian Rhythm Sleep Disorder, Jet Lag TypeView official trial listing → -
Status unknown NCT NCT05413486
Sleep, Obesity and Mental Disease - Biological Markers for the Evaluation of Circadian Rhythmicity
Esbjerg Hospital - University Hospital of Southern Denmark 86 participants Est. completion 2024-07-31 1 siteOther conditions: Bipolar Disorder, Schizophrenia, Obesity, Circadian Rhythm DisordersView official trial listing → -
Completed NCT NCT05419466
Kinetic of Compounds of a Melatonin-based Formulation in Healthy Subjects
Not yet reported Larena SAS 14 participants Est. completion 2023-05-22 1 site Stand-aloneOther conditions: Melatonin BioavailabilityView official trial listing → -
Completed NCT NCT05422599
Enhancement of Sleep Quality and Mood Following Supplementation With Lemon Balm in an Adult Population (Lemslp)
Not yet reported University of Reading 99 participants Est. completion 2023-05-23 1 siteOther conditions: Sleep Disturbance, Mood DisturbanceView official trial listing → -
Completed NCT NCT05439876
Getting SMART for Pediatric Epilepsy
Not yet reported, Not yet reported National Taiwan University Hospital 147 participants Est. completion 2025-01-03 1 site Stand-aloneOther conditions: Epilepsy in ChildrenView official trial listing → -
Terminated NCT NCT05440734
Exogenous Melatonin in Postmenopausal Women with Insomnia
Not yet reported Douglas Mental Health University Institute 6 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: InsomniaView official trial listing → -
Status unknown NCT NCT05454683
Melatonin and Zinc Administration on Cardinal Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Not yet reported Laboratorios Viñas, S.A. 106 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Chronic Fatigue Syndrome, Myalgic EncephalomyelitisView official trial listing → -
Status unknown NCT NCT05459272
Clinical Trial on a Food Supplement With Melatonin and Herbal Products to Improve Sleep Quality
Not yet reported Uriach Consumer Healthcare 50 participants Est. completion 2023-10-30 1 site Stand-aloneOther conditions: Sleep DisordersView official trial listing → -
Active, not recruiting NCT NCT05474846
Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer
Not yet reported, Not yet reported M.D. Anderson Cancer Center 169 participants Est. completion 2027-02-28 1 site Stand-aloneOther conditions: Sleep, Fatigue, Anxiety, Cancer, DepressionView official trial listing → -
Status unknown NCT NCT05483231
The Effect of Family Integrated Care on Melatonin Level in Very Low Birth Weight Infants
Not yet reported Children's Hospital of Fudan University 64 participants Est. completion 2024-04-30 1 siteOther conditions: Very Low Birth Weight InfantView official trial listing → -
Completed NCT NCT05483296
Effects of Afternoon and Evening Light on Teenagers' Melatonin Levels, Alertness, Sleepiness and Sleep
Not yet reported University Psychiatric Clinics Basel 27 participants Est. completion 2023-06-20 1 siteOther conditions: Healthy, Teenager, Healthy LifestyleView official trial listing → -
Completed NCT NCT05492812
Sedation and Nursing Management in EEG Recording in Children
Not yet reported Suleyman Demirel University 180 participants Est. completion 2021-12-31 1 site Stand-aloneOther conditions: Electroencephalography, Melatonin, Chloral Hydrate, Hydroxyzine, Sleep DeprivationView official trial listing → -
Completed NCT NCT05511740
Circadian as A Prognostic Factor For Radiation Response in Cervical Cancer
Not yet reported Universitas Indonesia 71 participants Est. completion 2014-07Other conditions: Cervical Cancer, Radiotherapy Side EffectView official trial listing → -
Completed NCT NCT05513547
Beneficial Effects of Daytime Light Exposure and Physical Activity on the Human Circadian Clock and Sleep
Not yet reported University Hospital, Basel, Switzerland 51 participants Est. completion 2025-09-12 1 siteOther conditions: Circadian SystemView official trial listing → -
Completed NCT NCT05521243
An Exploratory Investigation of a Supplement to Enhance Sleep Quality and Quantity
Not yet reported Beam 64 participants Est. completion 2022-09-30 1 site Stand-aloneOther conditions: Sleep, Sleep Disturbance, Sleep HygieneView official trial listing → -
Status unknown NCT NCT05536596
Pharmacological Treatment on the Recovery of Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy
Not yet reported, Not yet reported Universitat Internacional de Catalunya 220 participants Est. completion 2024-12-31 Stand-aloneOther conditions: Retrognathism, Prognathism, Orthognathic Surgery, Neurosensory DisorderView official trial listing → -
Active, not recruiting NCT NCT05543681
Clinical Trial on Agitation in Alzheimer's Dementia
Not yet reported IGC Pharma, LLC 164 participants Est. completion 2026-11 28 sitesOther conditions: Alzheimer Disease, Agitation,Psychomotor, Care Giving Burden, NPS, AggressionView official trial listing → -
Status unknown NCT NCT05552586
Melatonin Impact on the Outcomes of Myocardial Ischemia/Reperfusion Injury During Coronary Artery Bypass Grafting Surgery
Not yet reported Ain Shams University 22 participants Est. completion 2023-09Cardiovascular disease Other conditions: Coronary Artery Bypass GraftingView official trial listing → -
Completed NCT NCT05556811
HEaling LIght Algorithms for the ICU Patient
Not yet reported Charite University, Berlin, Germany 60 participants Est. completion 2024-05-31 1 siteOther conditions: Critical Care, PhototherapyView official trial listing → -
Status unknown NCT NCT05570526
Effect of Melatonin in Pediatric Hemodialysis Patients
Not yet reported Ain Shams University 40 participants Est. completion 2023-03-25 1 site Stand-aloneOther conditions: Hemodialysis Complication, Oxidative Stress, InflammationView official trial listing → -
Completed NCT NCT05593731
Platelet Rich Fibrin Versus Melatonin Around Dental Implants
Not yet reported Misr University for Science and Technology 30 participants Est. completion 2022-08-10 1 siteOther conditions: Patients With Missing TeethView official trial listing → -
Completed NCT NCT05596617
Safety and Efficacy of Medications COVID-19
Not yet reported Hospital San Carlos, Madrid 335 participants Est. completion 2022-03-31 1 site Stand-aloneOther conditions: Severe Covid-19View official trial listing → -
Completed NCT NCT05640934
Melatonin for Post Operative Delirium Prevention in Elderly Patients
Not yet reported Menoufia University 100 participants Est. completion 2023-07-05 1 siteOther conditions: Delirium in Old AgeView official trial listing → -
Status unknown NCT NCT05647148
The Effect of Progressive Relaxation Exercises on Sleep Quality
Not yet reported Ataturk University 60 participants Est. completion 2022-12-30 2 sitesOther conditions: Sleep Disturbance, Nursing CareView official trial listing → -
Status unknown NCT NCT05654415
Melatonin vs Sleep Deprivation for Nap EEG
Not yet reported IRCCS National Neurological Institute "C. Mondino" Foundation 30 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: EpilepsyView official trial listing → -
Enrolling by invitation NCT NCT05656768
Sleep and Circadian Contributions to Nighttime Blood Pressure
Not yet reported University of Alabama at Birmingham 1427 participants Est. completion 2028-12-30 1 site Stand-aloneOther conditions: Sleep, Circadian Rhythm, Blood Pressure, HypertensionView official trial listing → -
Completed NCT NCT05670444
Melatonin, Vitamins and Minerals Supplements for the Treatment of Covid-19 and Covid-like Illness
Not yet reported Hôpital Universitaire Sahloul 150 participants Est. completion 2023-02-28 1 siteOther conditions: Influenza -Like IllnessView official trial listing → -
Status unknown NCT NCT05680584
Comparison Between Oral Melatonin and Hydroxyzine in Pediatric Patients Undergoing Adenotonsillectomy
Not yet reported Minia University 78 participants Est. completion 2024-01-30 1 siteOther conditions: Effect of Drug, AnxietyView official trial listing → -
Status unknown NCT NCT05699876
Melatonin vs Gabapentin for Post Trauma Surgery
Not yet reported All India Institute of Medical Sciences 70 participants Est. completion 2023-11-30 1 site Stand-aloneOther conditions: Anxiety, PreoperarativeView official trial listing → -
Active, not recruiting NCT NCT05716906
Melatonin and Sleep Spindles in Autism
Not yet reported Massachusetts General Hospital 30 participants Est. completion 2027-01-01 1 site Stand-aloneOther conditions: Autism Spectrum DisorderView official trial listing → -
Status unknown NCT NCT05728892
Melatonin and Its Effect on the Perioperative Opioid Needs in Pediatric Patients Undergoing Laparoscopic Surgery.
Not yet reported Ain Shams University 72 participants Est. completion 2025-05-30 1 siteOther conditions: Postoperative PainView official trial listing → -
Status unknown NCT NCT05740969
Gene and Protein Expression Profiles After Treatment of Actinic Keratoses
Not yet reported Ismail Gögenur 48 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Actinic KeratosesView official trial listing → -
Completed NCT NCT05759416
Evaluation Efficacy of Melatonin Gel as Adjunctive Therapy in Chronic Periodontitis
Not yet reported Al-Azhar University 40 participants Est. completion 2021-03-01 1 siteOther conditions: Chronic PeriodontitisView official trial listing → -
Completed NCT NCT05759429
Effect of Melatonin on Oxidative Stress in Obese Adults (MELASTRESSOB)
Not yet reported Istituto Auxologico Italiano 20 participants Est. completion 2024-10-01 1 siteOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT05766436
Nebulized Dexmedetomidine VS ODF Melatonin for Peri Operative Anxiety and Emergence Agitation in Pediatric Day Surgery
Not yet reported nada moahmed aboelrouse 50 participants Est. completion 2023-09-30 1 siteOther conditions: Anxiety Acute, Emergence AgitationView official trial listing → -
Status unknown NCT NCT05784090
Correlation Between Melatonin Levels in Different Biological Fluids
Istituto Auxologico Italiano 36 participants Est. completion 2023-12-31 1 siteOther conditions: Neurodegenerative DiseasesView official trial listing → -
Status unknown NCT NCT05803174
Screening and Identification of Biomarkers for High Myopia by a Rapid Method
Beijing Tongren Hospital 120 participants Est. completion 2023-07-31 1 siteOther conditions: High MyopiaView official trial listing → -
Completed NCT NCT05820555
The Goodnight Screen Media Study
Not yet reported Baylor College of Medicine 170 participants Est. completion 2026-05-16 1 site Stand-aloneOther conditions: Sleep, Sleep HygieneView official trial listing → -
Status unknown NCT NCT05829148
The Effect of Dexmedetomidine, Melatonin and Pregabalin
Not yet reported Egymedicalpedia 120 participants Est. completion 2024-11-20 1 siteOther conditions: Endoscopic Sinus SurgeryView official trial listing → -
Completed NCT NCT05835258
Oral Bioavailability of Two Melatonin Supplements
Not yet reported Fundació Eurecat 12 participants Est. completion 2023-07-14 1 site Stand-aloneOther conditions: BioavailabilityView official trial listing → -
Completed NCT NCT05853757
A Clinical Study to Assess the Safety and Effectiveness of Herbal Supplement in Adult Human Subjects.
Not yet reported NovoBliss Research Pvt Ltd 32 participants Est. completion 2023-05-30 1 site Stand-aloneOther conditions: Difficulty in Sleep InitiationView official trial listing → -
Status unknown NCT NCT05857046
Cerebroprotective Effect of Melatonin in Stroke
Not yet reported Coordinación de Investigación en Salud, Mexico 100 participants Est. completion 2025-07-14 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT05870358
Melatonin Supports Non Surgical Periodontal Treatment in Patients With Type 2 Diabetes and Periodontitis
Not yet reported Yağmur Saraç Gül 55 participants Est. completion 2022-06-18 1 siteOther conditions: Diabetes Mellitus, Periodontitis, Melatonin, Matrix MetalloproteinasesView official trial listing → -
Status unknown NCT NCT05906563
Evaluation of Melatonin and Metformin Loaded Nanoparticles in the Treatment of Periodontal Intra-bony Defects
Not yet reported Amira ragab 52 participants Est. completion 2024-06 1 siteOther conditions: Bone Loss in JawView official trial listing → -
Status unknown NCT NCT05949827
Healing Light Algorithms for Nurses in the ICU
Charite University, Berlin, Germany 80 participants Est. completion 2024-12-31 1 siteOther conditions: Critical Care, PhototherapyView official trial listing → -
Completed NCT NCT05971485
Melatonin As an Analgesic in Preterm Neonate
Not yet reported Ain Shams University 40 participants Est. completion 2024-10-30 1 site Stand-aloneOther conditions: Preterm Neonate AnalgesiaView official trial listing → -
Completed NCT NCT05976451
Time Effect on the Predictability of Different Grafting for Gingival Recession RT 1
Not yet reported Ain Shams University 22 participants Est. completion 2023-03-03 1 site Stand-aloneOther conditions: Gingival Recession Types One(RT1)View official trial listing → -
Completed NCT NCT06012175
Melatonin for Knee Osteoarthritis Patients
Not yet reported Xiangya Hospital of Central South University 340 participants Est. completion 2025-09-24 1 site Stand-aloneOsteoarthritisView official trial listing → -
Status unknown NCT NCT06031961
The Premedication Properties of Oral Melatonin in Pediatrics Undergoing Therapeutic Cardiac Catheterization
Not yet reported Al-Azhar University 80 participants Est. completion 2024-08-15 1 siteOther conditions: AnesthesiaView official trial listing → -
Completed NCT NCT06053385
Impact of Commercial "Sleep Lotion" on Salivary Melatonin Levels and Sleep Quality in Undergraduates
Not yet reported University of Redlands 63 participants Est. completion 2023-04-20 1 site Stand-aloneOther conditions: SleepView official trial listing → -
Status unknown NCT NCT06076668
Dexmedetomidine Infusion Versus Oral Melatonin for Prevention of Intensive Care Delirium
Not yet reported Tanta University 90 participants Est. completion 2024-10-20 1 site Stand-aloneOther conditions: Dexmedetomidine, Melatonin, DeliriumView official trial listing → -
Completed NCT NCT06094699
Improving Sleep in the Neurology In-Patient Population
Not yet reported University of Pennsylvania 145 participants Est. completion 2025-07-01 1 site Stand-aloneOther conditions: SleepView official trial listing → -
Status unknown NCT NCT06096558
The Effects of Melatonin on Cardiovascular and Bone Metabolism Markers in Peritoneal Dialysis Patients
Not yet reported National Nutrition and Food Technology Institute 46 participants Est. completion 2024-05-01Other conditions: Peritoneal DialysisView official trial listing → -
Completed NCT NCT06103188
Comparing the Effect of Melatonin, Diazepam, and Placebo on Decreasing the Level of Anxiety Preoperatively
Not yet reported University of Jordan 87 participants Est. completion 2023-10-30 1 site Stand-aloneOther conditions: Anxiety, Preoperative AnxietyView official trial listing → -
Completed NCT NCT06125353
The Effect of Melatonin Supplementation on Fatigue Symptoms During Chemotherapy Treatment of Breast Cancer Patients
Not yet reported Harokopio University 56 participants Est. completion 2022-05-31 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT06146712
A Single-Group Study to Examine the Efficacy of a Melatonin Lotion With Magnesium to Improve Sleep Quality and Quantity
Not yet reported Asutra 35 participants Est. completion 2023-10-02 1 site Stand-aloneOther conditions: SleepView official trial listing → -
Status unknown NCT NCT06156059
Oral Bedtime Melatonin in Critically Ill Patients
Not yet reported Hospital San Carlos, Madrid 160 participants Est. completion 2026-04-01Cardiovascular disease Other conditions: Septic Shock, Cardiac ArrestView official trial listing → -
Completed NCT NCT06191523
The Effect of Melatonin as an Adjuvant Therapy for Preterm Neonates With Sepsis
Not yet reported Universitas Sebelas Maret 42 participants Est. completion 2023-10-20 1 site Stand-aloneOther conditions: Sepsis NewbornView official trial listing → -
Completed NCT NCT06192641
Melatonin Use in Patients With Climacterious Symptoms in the Perimenopause
Not yet reported Univates 24 participants Est. completion 2024-12-20 1 siteOther conditions: Perimenopausal DisorderView official trial listing → -
Completed NCT NCT06215573
Effect of a Novel Melatonin Supplement on Sleep Quality
Not yet reported University of Exeter 15 participants Est. completion 2024-04-18 1 site Stand-aloneOther conditions: SleepView official trial listing → -
Status unknown NCT NCT06236191
Improving Sleep of Children With Neurodevelopmental Disorders: Pulsed Current Stimulation Versus Melatonin
Not yet reported KK Women's and Children's Hospital 40 participants Est. completion 2024-09-30 1 siteOther conditions: Insomnia, Neurodevelopmental DisordersView official trial listing → -
Status unknown NCT NCT06237556
Melatonin on Anxiety and Sleep Quality in Adults Undergoing Coronary Artery Bypass Graft Surgery
Not yet reported Ain Shams University 30 participants Est. completion 2024-12-01 1 site Stand-aloneOther conditions: Melatonin, Anxiety, Sleep Quality, Coronary Artery Bypass GraftView official trial listing → -
Status unknown NCT NCT06260020
Development and Validation of a Comprehensive Module for Management of Sleep Disorders in ASD Children
Not yet reported All India Institute of Medical Sciences 25 participants Est. completion 2025-06-30 Stand-aloneOther conditions: Sleep Disorder, Autism Spectrum Disorder, Polysomnography, Actigraphy, Children, Behavior TherapyView official trial listing → -
Withdrawn NCT NCT06292000
Examining the Effects of Morning and Evening Exercise on Glucose Regulation in Adults With Prediabetes
Not yet reported University of Colorado, Denver Est. completion 2026-06 1 sitePrediabetes Other conditions: Obesity, Inactivity/Low Levels of ExerciseView official trial listing → -
Completed NCT NCT06310135
Filtered Eyewear to Prevent Light-induced Melatonin Suppression - Aim 1
Not yet reported Icahn School of Medicine at Mount Sinai 29 participants Est. completion 2024-10-31 1 siteOther conditions: Sleep QualityView official trial listing → -
Status unknown NCT NCT06355687
Melatonin in Obese Patients in Laparoscopic Cholecystectomy
Not yet reported Ain Shams University 60 participants Est. completion 2025-04Other conditions: AnesthesiaView official trial listing → -
Status unknown NCT NCT06372561
Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study
Not yet reported Suez Canal University 45 participants Est. completion 2024-10-02 1 site Stand-aloneOther conditions: Dental Caries in Children, Vital Pulp TherapyView official trial listing → -
Status unknown NCT NCT06374771
Analgesic Effect of Melatonin and Vitamin C Administration, Alone or In Combination in Major Abdominal Surgery.
Not yet reported Cairo University 60 participants Est. completion 2024-07-10 1 siteOther conditions: Postoperative PainView official trial listing → -
Completed NCT NCT06382610
Pharmacokinetics of Melatonin Administered in Oral, Lotion, and Bubble Bath Formulations
Not yet reported University of Redlands 12 participants Est. completion 2026-07-31 1 site Stand-aloneOther conditions: SleepView official trial listing → -
Completed NCT NCT06393296
A Study of Melatonin Concentration During Lactation
Mayo Clinic 88 participants Est. completion 2026-06-18 1 siteOther conditions: BreastfeedingView official trial listing → -
Completed NCT NCT06404086
RECOVER-SLEEP: Platform Protocol
Not yet reported Duke University 830 participants Est. completion 2025-12-31 47 sitesOther conditions: Long COVID, Long COVID-19, Hypersomnia, Sleep DisturbanceView official trial listing → -
Completed NCT NCT06404112
RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)
Not yet reported Duke University 469 participants Est. completion 2026-04-01 1 siteOther conditions: Long COVID, Long COVID-19, Sleep DisturbanceView official trial listing → -
Status unknown NCT NCT06405204
of Myo-inositol, Melatonin and Co-enzyme q10 on Ovarian Reserve
Not yet reported Beni-Suef University 200 participants Est. completion 2024-12-30 1 site Stand-aloneOther conditions: IVFView official trial listing → -
Status unknown NCT NCT06421454
Clinical Trial for the Evaluation of Melatonin in the Treatment of Pressure Ulcers
Not yet reported Fundacion Rioja Salud 50 participants Est. completion 2025-11-01 Stand-aloneOther conditions: Pressure UlcerView official trial listing → -
Completed NCT NCT06429059
ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize Treatments
Not yet reported Duke University 50 participants Est. completion 2025-06-24 2 sites Stand-aloneOther conditions: Amyotrophic Lateral Sclerosis ALSView official trial listing → -
Completed NCT NCT06455579
Bedtime Stories: A Sleep Health Education Program for Healthcare Providers
Not yet reported Boston Children's Hospital 25 participants Est. completion 2025-07-01 1 site Stand-aloneOther conditions: Sleep, Health-Related BehaviorView official trial listing → -
Completed NCT NCT06476392
Melatonin fOr CHronic bAck Pain (The MOCHA Trial)
Not yet reported Odense University Hospital 220 participants Est. completion 2026-04-13 1 site Stand-aloneOther conditions: Back Pain Lower Back Chronic, InsomniaView official trial listing → -
Completed NCT NCT06524674
Clinical Study to Compare the Effect of an Oral Rehydration Solution on the Rate of Absorption of Functional Ingredients
Not yet reported Liquid I.V. 37 participants Est. completion 2024-05-31 1 siteOther conditions: Absorption, PharmacokineticView official trial listing → -
Status unknown NCT NCT06533033
Melatonin Epigenetic Potential in Preventing Malignant Transformation of Oral Lichen Planus
Not yet reported Hams Hamed Abdelrahman 50 participants Est. completion 2024-08-01 1 site Stand-aloneOther conditions: Oral Lichen PlanusView official trial listing → -
Status unknown NCT NCT06546774
The Effect of Melatonin Supplementation on Cumulus Cells and IVF Outcomes
Not yet reported Kaohsiung Veterans General Hospital. 200 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Unrecognized ConditionView official trial listing → -
Status unknown NCT NCT06553963
Athlete Biochemical Monitoring and Nutritional Support
Not yet reported Chengdu Sport University 28 participants Est. completion 2024-09-20 Stand-aloneOther conditions: Weight ReductionView official trial listing → -
Completed NCT NCT06600633
Efficacy of Dietary Supplementation With Melatonin in Targeting Sleep Quality
Not yet reported Institute of Nutrition, Slovenia (Nutris) 32 participants Est. completion 2025-02-20 1 site Stand-aloneOther conditions: Sleep Onset Latency, Sleep QualityView official trial listing → -
Completed NCT NCT06606899
A Comparison Between Oral Melatonin With Nasal Sevoflurane Versus Oral Chloral Hydrate With Nasal Sevoflurane in Sedation of Children Undergoing Brain MRI
Not yet reported Ain Shams University 60 participants Est. completion 2024-12-30 1 site Stand-aloneOther conditions: Sedation for Children Undergoing MRIView official trial listing → -
Status unknown NCT NCT06617351
This Repeated Measures Parallel-group Investigation Will Examine the Influence of Short-term Melatonin Supplementation (5mg, 3 x Day for 72 Hours) on Cellular Responses, Functional Performance and Recovery Following an Acute Bout of Dynamic Resistance Exercise in Resistance Trained Men and Women
Not yet reported University of Central Florida 24 participants Est. completion 2025-07-31 1 site Stand-aloneOther conditions: Cell Migration, Cell Invasion, Exercise RecoveryView official trial listing → -
Status unknown NCT NCT06623643
"Salivary Melatonin and Cortisol Levels in Individuals with Bruxism"
Yuzuncu Yil University 100 participants Est. completion 2025-02-28Other conditions: BruxismView official trial listing → -
Completed NCT NCT06685679
Melatonin for Pulmonary Hypertension in Full Term Neonates
Not yet reported Ain Shams University 40 participants Est. completion 2025-03-15 1 site Stand-aloneOther conditions: Neonatal Diseases and Abnormalities, Neonatal Mortality, Pulmonary Arterial Hypertension, Pulmonary Arterial Hypertension, ChildrenView official trial listing → -
Completed NCT NCT06696378
Melatonin Supplementation and Exercise Program in Breast Cancer Women
Not yet reported University of Valladolid 42 participants Est. completion 2025-05-05 1 site Stand-aloneOther conditions: Female Breast Cancer, Older Adults, Exercise Trainning ProgrmamView official trial listing → -
Completed NCT NCT06724432
Analgesic and Antioxidant Effects of Melatonin in Pediatric Surgery
Not yet reported University of Parma 44 participants Est. completion 2024-09-01 2 sites Stand-aloneOther conditions: Postoperative Pain, Oxidative Stress ResponseView official trial listing → -
Completed NCT NCT06736821
Maxillary Sinus Augmentation by Xenograft Mixed With Melatonin
Not yet reported rehab soliman 16 participants Est. completion 2024-08-27 1 site Stand-aloneOther conditions: Bone HealingView official trial listing → -
Not yet recruiting NCT NCT06756828
Effects of 3-Month Melatonin Treatment on Regional Cerebellar Structure and Blood Biomarkers in Alzheimer's Disease Spectrum
Not yet reported Saint Vincent's Hospital, Korea 40 participants Est. completion 2026-12-30 Stand-aloneOther conditions: Elderly, Alzheimer Disease, Melatonin, Cognitive Decline, Biomarker with Neurodegeneration Patients, CerebellumView official trial listing → -
Not yet recruiting NCT NCT06777342
Effect of Preoperative Sleep Intervention on Postoperative Delirium in Adult Patients Undergoing Cardiac Surgery
Not yet reported Yan Fuxia 1281 participants Est. completion 2026-12-31 Stand-aloneOther conditions: Delirium - Postoperative, Sleep Problems, CABG, Valve SurgeryView official trial listing → -
Status unknown NCT NCT06801379
A Novel Inhaled Formulation of Melatonin to Treat Adults With Insomnia: Pharmacokinetic Study
Not yet reported Woolcock Institute of Medical Research 5 participants Est. completion 2026-05-01 1 site Stand-aloneOther conditions: InsomniaView official trial listing → -
Not yet recruiting NCT NCT06809751
Evaluating Efficacy and Safety of Oral Melatonin in Acute Central Serous Chorioretinopathy
Not yet reported, Not yet reported Mohsen Pourazizi 48 participants Est. completion 2025-06-01 Stand-aloneOther conditions: Central Serous Chorioretinopathy, Melatonin, Ocular Diseases, Visual Acuity, Macula AbnormalityView official trial listing → -
Active, not recruiting NCT NCT06812026
Effects of Melatonin and Massage After Third Molar Surgery
Bezmialem Vakif University 60 participants Est. completion 2026-05-10 1 siteOther conditions: MelatoninView official trial listing → -
Status unknown NCT NCT06816225
Association Between Sleep and Psychomotor Development in Early Childhood
Universidade do Porto 119 participants Est. completion 2025-12-01 1 siteOther conditions: SleepView official trial listing → -
Completed NCT NCT06816277
Application of Local Melatonin in Peri-implantitis
Not yet reported Universidad Complutense de Madrid 30 participants Est. completion 2023-07-15 1 site Stand-aloneOther conditions: PeriimplantitisView official trial listing → -
Completed NCT NCT06821425
Melatonin Gel as an Adjuvant in the Surgical Management of Intrabony Defects
Not yet reported Ain Shams University 20 participants Est. completion 2025-08-01 1 site Stand-aloneOther conditions: Periodontal Disease, AVDC Stage 3View official trial listing → -
Active, not recruiting NCT NCT06838104
Effect of Melatonin on Schizophrenic Symptoms: a Randomized Placebo-Controlled Trial
Not yet reported Lahore General Hospital 76 participants Est. completion 2025-06-05 1 site Stand-aloneOther conditions: Schizophrenia Disorders, Psychotic DisorderView official trial listing → -
Active, not recruiting NCT NCT06859957
Melatonin for Patients With Chronic Low Back Pain
Not yet reported Bart Koes 222 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Chronic Low-back Pain (cLBP)View official trial listing → -
Completed NCT NCT06868745
Effects of Melatonin Supplementation on Sleep Quality in Patients With Advanced Glaucoma
Not yet reported University of Sao Paulo 64 participants Est. completion 2024-06-26 1 site Stand-aloneOther conditions: Glaucoma, Sleep Disturbance, Circadian Rhythm, Melatonin, ActigraphyView official trial listing → -
Completed NCT NCT06872944
Effect of Melatonin on Postoperative Pain After Simple Nephrectomy
Not yet reported Cairo University 40 participants Est. completion 2025-07-07 2 sites Stand-aloneOther conditions: Pain Score (VAS) at 24 h PostoperativelyView official trial listing → -
Completed NCT NCT06894108
The Effectiveness of a Proprietary of a Botanical Extract on Sleep Quality
Not yet reported Nutraceuticals Research Institute 89 participants Est. completion 2025-04-30 1 siteOther conditions: SleepView official trial listing → -
Completed NCT NCT06898008
Characterization of Children with Complaints of Excessive Daytime Sleepiness
Hospices Civils de Lyon 400 participants Est. completion 2024-10-31 1 siteOther conditions: Excessive Daytime SleepinessView official trial listing → -
Completed NCT NCT06898463
Comparison Of The Effects Of Melatonin Premedication And Ketamine On Postoperative Sleep Quality İn Rhinoplasty
Not yet reported Konya City Hospital 183 participants Est. completion 2024-12-25 1 siteOther conditions: Postoperative Sleep DisturbancesView official trial listing → -
Completed NCT NCT06910345
Effect of Melatonin Patches on Sleep in Urological Surgery
Not yet reported Atlas University 60 participants Est. completion 2025-05-15 1 site Stand-aloneOther conditions: Urological SurgeryView official trial listing → -
Not yet recruiting NCT NCT06935292
Oral Melatonin VS Nebulized Dexmedetomidine Premedication on Attenuation of Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation in Hypertensive Patients
Not yet reported, Not yet reported Tanta University 70 participants Est. completion 2026-04 1 site Stand-aloneOther conditions: Tracheal Intubation Morbidity, Laryngoscopy, Hemodynamic ResponseView official trial listing → -
Completed NCT NCT06997263
Sublingual Melatonin for Anxiety and Pain in Elective Gynecologic Surgery
Not yet reported Benha University 96 participants Est. completion 2025-01-15 1 site Stand-aloneOther conditions: Anxiety, Postoperative Pain, AnesthesiaView official trial listing → -
Not yet recruiting NCT NCT07003243
Effectiveness of Topical Application of Melatonin On Bone Density and Implant Stability In Immediate Implantation
Not yet reported University of Baghdad 25 participants Est. completion 2026-05 1 site Stand-aloneOther conditions: Immediate Implant Placement, Melatonin ProductionView official trial listing → -
Active, not recruiting NCT NCT07034560
Effectiveness of Oral Melatonin vs Oral Tranexamic Acid in the Treatment and Recurrence of Melasma
Not yet reported Thammasat University 75 participants Est. completion 2025-11-06 1 site Stand-aloneOther conditions: Melasma, Treatment Outcome, RecurrenceView official trial listing → -
Completed NCT NCT07049783
Examining the Circadian Timing Effects of the Hypotensive Response to Exercise
Not yet reported Freda Patterson 8 participants Est. completion 2026-10-01 1 site Stand-aloneOther conditions: Young Adults, Hypertension, Post-Exercise Hypotension, Circadian RhythmView official trial listing → -
Enrolling by invitation NCT NCT07062757
Lymphatic Drainage Massage and Melatonin in Post-Orthognathic Surgery Pain and Edema
Not yet reported Bezmialem Vakif University 40 participants Est. completion 2027-05-30 1 site Stand-aloneOther conditions: Dentofacial Deformities, Edema, PainView official trial listing → -
Not yet recruiting NCT NCT07067307
Melatonin in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
Not yet reported, Not yet reported Mansoura University 80 participants Est. completion 2026-03 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT07090720
Melatonin Effects on the Left Ventricular Function in Neonates With Persistent Pulmonary Hypertension
Not yet reported Tanta University 80 participants Est. completion 2025-01-01 1 site Stand-aloneOther conditions: Melatonin, Left Ventricular Function, Neonates, Persistent Pulmonary HypertensionView official trial listing → -
Completed NCT NCT07095270
Evaluation of Circadian OS Technology on Melatonin Suppression
Not yet reported Icahn School of Medicine at Mount Sinai 10 participants Est. completion 2025-12-31 1 siteOther conditions: Circadian DisruptionView official trial listing → -
Not yet recruiting NCT NCT07096635
Oral Melatonin With Intra Articular Analgesia on Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction
Not yet reported Assiut University 50 participants Est. completion 2027-10-01Other conditions: Pain Relief After Arthroscopic Anterior Cruciate Ligament ReconstructionView official trial listing → -
Completed NCT NCT07103564
The Effect of Local Melatonin Application Around Immediately Placed Implants in the Maxillary Premolar
Not yet reported Hams Hamed Abdelrahman 24 participants Est. completion 2025-07-15 1 site Stand-aloneOther conditions: Dental Implants, Osteoprotegerin, MelatoninView official trial listing → -
Completed NCT NCT07138443
Influence of Melatonin on Cardiovascular and Thermoregulatory Responses to Stress
Not yet reported Baylor University 16 participants Est. completion 2026-07-20 1 site Stand-aloneOther conditions: Stress, Mental StressView official trial listing → -
Completed NCT NCT07162272
The Efficacy of Melatonin Patches on Dental Anxiety in Children
Not yet reported Ain Shams University 52 participants Est. completion 2025-08-29 1 site Stand-aloneOther conditions: Dental Anxiety, ChildrenView official trial listing → -
Enrolling by invitation NCT NCT07169383
Oral Melatonin Versus Oral Tranexamic Acid in the Management of Melasma
Not yet reported Hina Malik 160 participants Est. completion 2025-12-28 1 siteOther conditions: Melasma (Facial Melasma)View official trial listing → -
Active, not recruiting NCT NCT07173699
Evaluation of the Effect of Salivary Melatonin Levels on Postoperative Pain and Sleep Quality Following Endodontic Treatments Performed at Different Days and Times
Not yet reported Ataturk University 45 participants Est. completion 2026-07-20 1 site Stand-aloneOther conditions: Postoperative Pain After Endodontic TreatmentView official trial listing → -
Completed NCT NCT07192835
Effect of Fruit Elicitation With Melatonin on Human Health
Not yet reported Universidad Miguel Hernandez de Elche 22 participants Est. completion 2025-08-01 1 site Stand-aloneOther conditions: Healthy, Dietary Bioavailability, Plant Extracts, Phenolic Compounds, MelatoninView official trial listing → -
Completed NCT NCT07200167
Study of the Efficacy of Dietary Supplementation in Targeting Sleep Quality (NutriSom-01B)
Not yet reported Institute of Nutrition, Slovenia (Nutris) 70 participants Est. completion 2026-07-13 1 siteOther conditions: Sleep Onset Latency, Sleep QualityView official trial listing → -
Not yet recruiting NCT NCT07221968
Melatonin for the Treatment of DEE-SWAS
Not yet reported Hugo W. Moser Research Institute at Kennedy Krieger, Inc. 3 participants Est. completion 2028-12-30 Stand-aloneOther conditions: CSWS, Developmental and/or Epileptic Encephalopathies, Electrical Status Epilepticus in SleepView official trial listing → -
Enrolling by invitation NCT NCT07295470
Sleep and Activity For Eating Disorders
Not yet reported Istituto Auxologico Italiano 75 participants Est. completion 2027-07 1 siteObstructive sleep apnea Other conditions: Eating Disorders, Binge Eating DisorderView official trial listing → -
Active, not recruiting NCT NCT07305350
EFFICACY OF MELATONIN IN MANAGEMENT OF HYPOXIC ISCHEMIC ENCEPHALOPATHY (HIE) IN NEONATES
Not yet reported University of Child Health Sciences and Children's Hospital, Lahore 110 participants Est. completion 2026-05-10 1 site Stand-aloneOther conditions: Hypoxic Ischaemic Encephalopathy (HIE)View official trial listing → -
Completed NCT NCT07316582
Melatonin Loaded in Injectable Platelet-Rich Fibrin in the Management Periodontitis
Not yet reported Al-Azhar University 30 participants Est. completion 2026-07-01 1 site Stand-aloneOther conditions: Periodontitis Stage IIView official trial listing → -
Active, not recruiting NCT NCT07318974
Melatonin Therapy for Improving ICSI Outcomes in Women With Diminished Ovarian Reserve
Not yet reported Benha University 64 participants Est. completion 2026-03 1 siteOther conditions: ICSView official trial listing → -
Not yet recruiting NCT NCT07334197
Effect of Melatonin on Left Ventricular Reverse Remodeling and Inflammation in Peripartum Cardiomyopathy
Not yet reported Tanta University 25 participants Est. completion 2029-12-30 Stand-aloneOther conditions: Ppm, CardiomyopathyView official trial listing → -
Not yet recruiting NCT NCT07336095
Melatonin vs Midazolam in Children Undergoing Tonsillectomy
Not yet reported Ain Shams University 195 participants Est. completion 2026-08Other conditions: Emergence Delirium, Anesthesia, Child, Anxiety, Midazolam Premedication, Melatonin Bioavailability, TonsillectomyView official trial listing → -
Completed NCT NCT07343947
Melatonin Supplementation in Ovarian Response
Not yet reported University of Sao Paulo General Hospital 80 participants Est. completion 2023-12-01 1 site Stand-aloneOther conditions: Infertility, Infertility (IVF Patients), Infertile Women Undergoing IVF or ICSIView official trial listing → -
Completed NCT NCT07349459
Cardioprotective Effect of Melatonin Versus Vitamin D in Breast Cancer Patients Receiving Doxorubicin
Not yet reported Tanta University 90 participants Est. completion 2026-05-30 1 site Stand-aloneOther conditions: Melatonin, Breast Cancer Patients Diagnosed, Vitamin D Concentration, DoxorubicinView official trial listing → -
Not yet recruiting NCT NCT07369284
Melatonin for Glycemic Control in Gestational Diabetes Mellitus
Not yet reported Obstetrics & Gynecology Hospital of Fudan University 150 participants Est. completion 2027-08 Stand-aloneOther conditions: Gestational DiabetesView official trial listing → -
Active, not recruiting NCT NCT07374523
Clinical and Radiographic Evaluation of Local Melatonin Application on Osseointegration of Immediate Mandibular Implants
Not yet reported Suez Canal University 16 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: Implant TherapyView official trial listing → -
Active, not recruiting NCT NCT07374536
Clinical and Radiographic Evaluation of Local Application of Melatonin on Postoperative Outcomes After Surgical Removal of Impacted Mandibular Third Molar
Not yet reported Suez Canal University 20 participants Est. completion 2026-08-15 1 site Stand-aloneOther conditions: Impact MolarView official trial listing → -
Enrolling by invitation NCT NCT07375693
Effect of Melatonin on Oxidative Stress Parameters in Levodopa-Treated Parkinson's Disease Patients
Not yet reported Bangladesh Medical University 70 participants Est. completion 2026-09-15 1 site Stand-aloneOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT07380568
Melatonin on Post Operative Pain After CS
Not yet reported Benha University 60 participants Est. completion 2026-04-01 1 siteOther conditions: Pain Management, Pain After Surgery, Cesarean Section PainView official trial listing → -
Completed NCT NCT07382843
Melatonin Agonist for Shift-time Workers.
Not yet reported Tri-Service General Hospital (TSGH) 61 participants Est. completion 2025-12-31 1 siteOther conditions: Circadian Rhythm DisordersView official trial listing → -
Completed NCT NCT07385768
Effect of an Eye Mask-Based Blackout Protocol on Sleep Quality and Melatonin
Not yet reported Ataturk University 60 participants Est. completion 2025-06-01 1 siteOther conditions: Sleep Disturbance, Circadian Rhythm Sleep Disorders, Intensive Care Unit PatientsView official trial listing → -
Not yet recruiting NCT NCT07418554
Sleep Disturbances in Children and Adolescents With Post-traumatic Stress Disorder (PTSD): a Randomized Double-blind Placebo-controlled Trial to Investigate the Efficacy of Pediatric Prolonged-release Melatonin
Not yet reported University Hospital, Strasbourg, France 120 participants Est. completion 2029-06-01 1 site Stand-aloneOther conditions: Post-traumatic Stress Disorder (PTSD), Current Significant Sleep DisturbancesView official trial listing → -
Enrolling by invitation NCT NCT07442162
Effects of Melatonin on Excessive Crying in Neonates. A Randomized Controlled Clinical Trial.
Not yet reported, Not yet reported Al-Hadba university 165 participants Est. completion 2026-04-01 1 siteOther conditions: CryingView official trial listing → -
Completed NCT NCT07443150
The Effect of BWSTT on Neuroendocrine Profile and Functional Recovery in Stroke Patients
Not yet reported Jagiellonian University 40 participants Est. completion 2024-05-24 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT07461402
Plant Protein With Ashwagandha-Rhodiola for Sleep Quality
Not yet reported Universidad Pablo de Olavide 100 participants Est. completion 2025-12-04 1 site Stand-aloneOther conditions: Sleep Quality, Sleep Disorders, InsomniaView official trial listing → -
Completed NCT NCT07475156
The Effect of Dexmedetomidine Infusion Alone Versus the Combination of Dexmedetomidine and Melatonin on Reduction of Post-operative Delirium (POD) After Open Brain Surgeries
Not yet reported Ain Shams University 100 participants Est. completion 2026-02-01 1 siteOther conditions: Post Operative DeleriumView official trial listing → -
Not yet recruiting NCT NCT07495605
Effect of 1% Melatonin Gel Versus Calcium Hydroxide as an Intracanal Medicament on the Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic Pulp.
Not yet reported Cairo University 50 participants Est. completion 2027-12 Stand-aloneOther conditions: Intensity of Postoperative Pain, Bacterial Load Reduction and Periapical MMP-9 Levels in Patients With Necrotic PulpView official trial listing → -
Not yet recruiting NCT NCT07503600
The Effect of Adjunctive Melatonin With Colistin in Patients With Multidrug-Resistant Gram-Negative Bacterial Infections
Not yet reported Ain Shams University 70 participants Est. completion 2026-08-26 Stand-aloneOther conditions: Multidrug-Resistant Gram-Negative Bacterial Infections, Antimicrobial ResistanceView official trial listing → -
Not yet recruiting NCT NCT07514507
Optimization of Melatonin Administration in Healthy Adults
Not yet reported IRCCS Fondazione Stella Maris 14 participants Est. completion 2026-08 1 site Stand-aloneOther conditions: Sleep DisordersView official trial listing → -
Not yet recruiting NCT NCT07533578
Chrononutrition in Preterm Infants: a Randomised Controlled Trial of Time-matched Breast Milk Feeding and Its Effects on Sleep and Circadian Development
Not yet reported Luzerner Kantonsspital 200 participants Est. completion 2031-12-30 1 siteOther conditions: Infant Sleep Problems, Circadian Rhythm, NeurodevelopmentView official trial listing → -
Enrolling by invitation NCT NCT07549295
Melatonin and Perinatal Outcomes in MVM-Related Fetal Growth Restriction (MIMVMFGR)
Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 240 participants Est. completion 2028-11-30 1 site Stand-aloneOther conditions: Fetal Growth Restriction (FGR)View official trial listing → -
Completed NCT NCT07550751
Optimal Dosage of Melatonin for Preoperative Sedation in FESS
Not yet reported Aswan University Hospital 160 participants Est. completion 2025-10-01 1 siteOther conditions: Clinical TrialView official trial listing → -
Completed NCT NCT07568873
Melatonin vs Metoprolol or Dexmedetomidine to Improve Surgical Field in FESS
Not yet reported Zagazig University 28 participants Est. completion 2025-01-15 1 siteOther conditions: Stress Response of Endotracheal Intubation and Surgical Field Clarity in FESSView official trial listing → -
Not yet recruiting NCT NCT07576764
Pediatric Prolonged-Release Melatonin for Sleep Disturbances in Children and Adolescents With Anorexia Nervosa (MELSom-ANOREXIA)
Not yet reported Assistance Publique Hopitaux De Marseille 120 participants Est. completion 2029-01-01 1 site Stand-aloneObstructive sleep apnea Other conditions: Sleep Disorders in ChildrenView official trial listing → -
Completed NCT NCT07592442
Effect of Melatonin Supplementation on Excecutive Functions, Sleep Quality and Glycemic Metrics Among Adolescents With Type 1 Diabetes Mellitus
Not yet reported Ain Shams University 70 participants Est. completion 2026-01-24 1 siteOther conditions: Type 1 Diabetes (T1D)View official trial listing → -
Completed NCT NCT07600528
A Exploratory Study of NatureU Sweet Dream on Sleep Outcomes
Not yet reported OmniSolutions Laboratory Holdings Limited 17 participants Est. completion 2024-04-17 1 site Stand-aloneOther conditions: Sleep Disturbance, Sleep QualityView official trial listing → -
Completed NCT NCT07605767
Adjunctive Topical Melatonin Gel in Non-Surgical Periodontal Therapy for Periodontitis
Not yet reported Liaquat College of Medicine and Dentistry 30 participants Est. completion 2026-04-10 1 site Stand-aloneOther conditions: Periodontal Disease, MelatoninView official trial listing → -
Completed NCT NCT07610876
Autologous Demineralized Dentin Graft With or Without Melatonin for Immediate Implant Osseointegration
Not yet reported Suez Canal University 30 participants Est. completion 2026-10-15 1 site Stand-aloneOther conditions: Dental Implants, Immediate Implant Placement, OsseointegrationView official trial listing → -
Completed NCT NCT07651605
Pistacho and Sleep Quality
Not yet reported Universidad Autonoma de Queretaro 28 participants Est. completion 2021-11-01 1 site Stand-aloneOther conditions: Circadian RhythmView official trial listing → -
Not yet recruiting NCT NCT07652801
COMPARISON OF OUTCOME OF HYPOXIC ISCHEMIC ENCEPHLOPATHY MANAGED WITH COMBINATION OF MAGNESIUM SULPHATE AND MELATONIN VERSUS MAGNESIUM SULPHATE ALONE
Not yet reported University of Child Health Sciences and Children's Hospital, Lahore 80 participants Est. completion 2026-12-31 Stand-aloneOther conditions: HIE - Hypoxic - Ischemic EncephalopathyView official trial listing → -
Completed NCT NCT07669766
Somato® (Phytomelatonin) Versus Synthetic Melatonin and Placebo on Sleep Quality
Not yet reported Nutraland USA, Inc. 244 participants Est. completion 2026-04-17 1 site Stand-aloneOther conditions: SleepView official trial listing → -
Not yet recruiting NCT NCT07691996
Effects of Melatonin on Sleep Architecture of Critically Ill Patients in the ICU
Not yet reported Rutgers, The State University of New Jersey 30 participants Est. completion 2028-01 Stand-aloneOther conditions: Critical Illness, ICU, ICU Hospitalization, Melatonin, SleepView official trial listing → -
Not yet recruiting NCT NCT07721324
Effect of Melatonin Administration on Systemic Lupus Erythematosus Patients
Not yet reported, Not yet reported Ain Shams University 64 participants Est. completion 2026-11-21 1 site Stand-aloneOther conditions: Therapy, TreatmentView official trial listing → -
Not yet recruiting NCT NCT07732725
Comparison Between the Effect of Two Different Doses of Oral Melatonin on Sleep Quality After Total Hip Arthroplasty
Not yet reported Benha University 150 participants Est. completion 2026-11-04 1 site Stand-aloneOther conditions: Sleep DisturbanceView official trial listing → -
Completed NCT NCT07735806
The Effect of Topical Application of Hyaluronic Acid and Melatonin Mixture Following Surgical Extraction of Impacted Mandibular Third Molars .
Not yet reported Kafrelsheikh University 40 participants Est. completion 2026-08-02 1 site Stand-aloneOther conditions: Impacted Mandibular Third MolarView official trial listing → -
Enrolling by invitation NCT NCT07743255
Preventive Role of Melatonin and Propranolol Administration in Pediatric Migraine
Not yet reported Nishtar Medical University 60 participants Est. completion 2026-12-10 1 site Stand-aloneOther conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT07769164
A Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Effects of Various Cannabinoids on Sleep Quality
Not yet reported Cannabis Science Innovations, LLC 332 participants Est. completion 2024-08-31 1 site Stand-aloneOther conditions: Sleep Disturbance, Sleep QualityView official trial listing → -
Active, not recruiting NCT NCT07811492
CIRCA-MED WP1 & WP3 - Circadian Rhythms in ICU Patients
Charite University, Berlin, Germany 25000 participants Est. completion 2029-09-30 1 siteOther conditions: Circadian RhythmView official trial listing → -
Not yet recruiting NCT NCT07813936
Locally Delivered Melatonin Gel in Management of Stage II Grade B Periodontitis
Not yet reported Alexandria University 23 participants Est. completion 2027-09-30 1 site Stand-aloneOther conditions: Periodontal DiseasesView official trial listing → -
Completed NCT NCT07825961
Efficacy of Melatonin in the Treatment of Diabetic Nephropathy Compared With Folic Acid
Not yet reported Tanta University 75 participants Est. completion 2026-07-01 1 site Stand-aloneChronic kidney disease Other conditions: Melatonin, Folic AcidView official trial listing → -
Completed NCT NCT07829393
Topical Melatonin for Immediate Implants in Chronically Infected Extraction Sockets
Not yet reported Mansoura University 60 participants Est. completion 2026-07-25 1 site Stand-aloneOther conditions: Chronic Apical Periodontitis, Dental Implantation, Infected Extraction SocketView official trial listing → -
Not yet recruiting NCT NCT07840560
Sleep Harmonization Via Bundled Team-Based Interventions in the ICU
Not yet reported University of California, San Diego 62500 participants Est. completion 2031-03 8 sitesOther conditions: Sleep Deprivation, Critical Illness, Sleep-Wake Disorders, Bundle Care, Implementation Science, DeliriumView official trial listing → -
Not yet recruiting NCT NCT07842900
Oral Melatonin as Adjunctive Therapy in Adults With Atopic Dermatitis
Not yet reported Can Tho University of Medicine and Pharmacy 130 participants Est. completion 2027-12-10 Stand-aloneOther conditions: Atopic DermatitisView official trial listing → -
Completed NCT NCT07848464
Cronobióticos Naturales
Not yet reported Universidad San Sebastián 20 participants Est. completion 2026-09-16 1 site Stand-aloneOther conditions: Circadian Rhythm Disruption, Healthy VolunteersView official trial listing → -
Completed NCT NCT07865988
Efficacy of High-Dose Melatonin in Alleviating Radiotherapy-Induced Fatigue in Breast Cancer Patients
Not yet reported, Not yet reported Menoufia University 51 participants Est. completion 2026-08-20 1 site Stand-aloneOther conditions: Breast Cancer, Radiotherapy Induced FatigueView official trial listing → -
Completed NCT NCT07889466
Circadian-informed Optimal Bedtime
Not yet reported Massachusetts Institute of Technology 203 participants Est. completion 2026-01-30 1 siteOther conditions: Sleep, Alertness, Fatigue, Mood, and Performance, Well-beingView official trial listing → -
Active, not recruiting NCT NCT07900321
Equivalence of Oral Melatonin and Oral Midazolam in Preoperative Anxiolysis for Pediatric Fast-Track Cardiac Surgery
Not yet reported, Not yet reported Ain Shams University 100 participants Est. completion 2026-12-01 1 siteOther conditions: Comparative EffectivenessView official trial listing → -
Enrolling by invitation NCT NCT07906184
Recreational Badminton, Sleep and Melatonin
Not yet reported Inonu University 18 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: Sedentary BehaviorView official trial listing → -
Not yet recruiting NCT NCT07921355
Melatonin in Posterior Mandible Extraction Socket
Not yet reported Cairo University 40 participants Est. completion 2027-11-10 Stand-aloneOther conditions: Bone LossView official trial listing → -
Not yet recruiting NCT NCT07926282
Adjunctive Melatonin Gel With MINST on GCF Galectin-3 and IL-1 in Stage III-IV Periodontitis
Not yet reported Badr University 40 participants Est. completion 2027-04 Stand-aloneOther conditions: Periodontitis, Periodontitis (Stage 3), Periodontitis Stage IVView official trial listing → -
Active, not recruiting NCT NCT07932444
Melatonin in Stroke
Not yet reported King Edward Medical University 130 participants Est. completion 2027-12-31 1 site Stand-aloneCardiovascular disease Other conditions: CVAView official trial listing → -
Not yet recruiting NCT NCT07932938
The Pediatric Sleep Study
Not yet reported Olly, PBC 200 participants Est. completion 2027-07 1 siteOther conditions: Sleep Quality, Sleep and Circadian ProblemsView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Oyster Shell Calcium Carbonate, Crude, Melatonin Pro, Melatonin, Melatonin Phenolic, MELATONIN CORD, Melatonin 5 mg
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
