Data source: ClinicalTrials.gov · trial data as of Oct 10, 2026
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See recruiting studies for NIO752 and check eligibility with the study team.
Trial details
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Recruiting
NCT NCT06372821
A Trial Evaluating the Effect of NIO752 on Tau Synthesis Measured by a Process Known as SILK
Not yet reported
University College, London
10 participants
Est. completion 2026-07
2 sites
Stand-alone
Other conditions: Alzheimer Disease, Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 1 (Disorder), Autosomal Dominant Alzheimer Disease Due to Mutation of Presenilin 2 (Disorder), Autosomal Dominant Alzheimer Disease Due to Mutation of Amyloid Precursor Protein (Disorder)
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Recruiting
NCT NCT07498426
A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy
Not yet reported
Novartis Pharmaceuticals
300 participants
Est. completion 2031-07-18
42 sites
Stand-alone
Other conditions: Progressive Supranuclear Palsy Richardson Syndrome (PSP-RS)
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Completed
NCT NCT04539041
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy
Not yet reported
Novartis Pharmaceuticals
59 participants
Est. completion 2024-10-17
12 sites
Stand-alone
Other conditions: Progressive Supranuclear Palsy (PSP)
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Active, not recruiting
NCT NCT05469360
Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants
Not yet reported
Novartis Pharmaceuticals
38 participants
Est. completion 2027-09-24
10 sites
Stand-alone
Other conditions: Alzheimer Disease, Mild Cognitive Impairment
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Not yet recruiting
NCT NCT07868328
A Study to Evaluate the Safety, Tolerability and Pharmacodynamics of NIO752 in Primary Tauopathies
Not yet reported
Novartis Pharmaceuticals
48 participants
Est. completion 2030-05-20
Stand-alone
Other conditions: Progressive Supranuclear Palsy, Corticobasal Degeneration, Frontotemporal Lobar Degeneration, Tauopathies
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Efficacy history
Safety
Sources
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