About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Naproxen Sodium
- Company
- Rockefeller University
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 14 recruiting
Efficacy results: Not yet reported
14 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 29, 2026
Find a Clinical Trial Near Me
See recruiting studies for Naproxen Sodium and check eligibility with the study team.
Trial details
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Recruiting NCT NCT04725422
CHronic Nonbacterial Osteomyelitis International Registry
Seattle Children's Hospital 2000 participants Est. completion 2050-08 1 siteOther conditions: Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal OsteomyelitisView official trial listing → -
Recruiting NCT NCT04875702
Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout
Not yet reported Massachusetts General Hospital 650 participants Est. completion 2028-10-31 7 sitesOther conditions: GoutView official trial listing → -
Recruiting NCT NCT05050409
SMART Embedded Intervention for Military Postsurgical Engagement Readiness
Not yet reported University of Utah 500 participants Est. completion 2027-10 1 siteOther conditions: Knee Pain ChronicView official trial listing → -
Recruiting NCT NCT05411718
A Phase IIa Randomized, Double-Blinded Clinical Trial of Naproxen or Aspirin for Cancer Immune Interception in Lynch Syndrome
Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2026-11-30 1 siteOther conditions: T Cells, Colorectal Cancer, Lynch SyndromeView official trial listing → -
Recruiting NCT NCT05413525
Ultrasound-guided Manual Vacuum Aspiration (USG-MVA)
Chinese University of Hong Kong 200 participants Est. completion 2026-06-30 2 sitesOther conditions: Ultrasound-guided Manual Vacuum Aspiration, First Trimester Spontaneous AbortionView official trial listing → -
Recruiting NCT NCT05722002
Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial
Not yet reported University of Michigan 900 participants Est. completion 2027-08-31 8 sitesOther conditions: Surgery, Pain, PostoperativeView official trial listing → -
Recruiting NCT NCT05851976
Duloxetine for LBP
Not yet reported Montefiore Medical Center 120 participants Est. completion 2027-05 1 siteOther conditions: Back Pain, LowView official trial listing → -
Recruiting NCT NCT06562816
Comparing Trypsin-Chymotrypsin and Naproxen Sodium for Post-endodontic Treatment Pain
Not yet reported Dow University of Health Sciences 100 participants Est. completion 2025-01-31 1 siteOther conditions: Effect of DrugView official trial listing → -
Recruiting NCT NCT06693362
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of Uterine Blood Mesenchymal Stem Cells Injection for the Treatment of Severe Pneumonia Caused by Viruses
Not yet reported Ruijin Hospital 60 participants Est. completion 2028-06-30 1 siteOther conditions: Severe Viral Pneumonia(Not Include COVID-19)View official trial listing → -
Recruiting NCT NCT06861920
NSAID Use for Treating Dysmenorrhea and Preventing Chronic Pelvic Pain (NSAID HEAL)
Not yet reported Endeavor Health 600 participants Est. completion 2030-07 1 siteOther conditions: Dysmenorrhea, Chronic Pelvic Pain, Pelvic PainView official trial listing → -
Recruiting NCT NCT07103694
i-NEED: NEw migrainE Drugs Database
IRCCS San Raffaele Roma 2641 participants Est. completion 2026-12-31 2 sitesOther conditions: Episodic Migraine, Chronic Migraine, Medication Overuse HeadacheView official trial listing → -
Recruiting NCT NCT07173231
Use of VR for Diagnostic Hysteroscopy
Not yet reported St. Justine's Hospital 45 participants Est. completion 2027-07 1 siteOther conditions: Hysteroscopy, Anxiety, PainView official trial listing → -
Recruiting NCT NCT07493226
Efficacy of Chemically Distinct Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Pain Phenotypes in Adhesive Capsulitis
Not yet reported Konya Beyhekim Training and Research Hospital 120 participants Est. completion 2027-03-30 1 siteOther conditions: Frozen Shoulder, Adhesive Capsulitis, Shoulder Pain, NSAID (Non-Steroidal Anti-Inflammatory Drug), Nociplastic Pain, Neuropathic PainView official trial listing → -
Recruiting NCT NCT07901959
Safety and Tolerability of Metformin and Naproxen for Cancer Prevention in Fanconi Anemia
Not yet reported Rockefeller University 80 participants Est. completion 2031-10-14 2 sitesOther conditions: Fanconi Anemia, Head and Neck Cancer, Squamous Cell Carcinoma, Squamous Cell Cancer of Head and Neck (SCCHN)View official trial listing → -
Completed NCT NCT00004845
A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study)
Not yet reported, Not yet reported National Institute on Aging (NIA) Est. completion 2001-12 40 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00007189
Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT)
Not yet reported Seattle Institute for Biomedical and Clinical Research 2625 participants 6 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00034853
Meloxicam [Mobic] in Juvenile Rheumatoid Arthritis (JRA)
Not yet reported Boehringer Ingelheim 180 participants 37 sitesOther conditions: Arthritis, Juvenile RheumatoidView official trial listing → -
Completed NCT NCT00092729
An Investigational Drug Study in the Treatment of Primary Dysmenorrhea (0663-064)
Not yet reported Organon and Co 129 participants Est. completion 2002-12-06 Stand-aloneOther conditions: DysmenorrheaView official trial listing → -
Completed NCT NCT00114049
Dental Pain (Following Third Molar Tooth Extraction) Study
Not yet reported GlaxoSmithKline 300 participants Est. completion 2005-04 1 siteOther conditions: Dental Pain, Surgery, DentalView official trial listing → -
Completed NCT NCT00137033
Celebrex Low Dose ASA Study Examining the Incidence of Gastroduodenal Ulcers in a Healthy Population
Not yet reported Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 605 participants Est. completion 2005-07 23 sitesOther conditions: Peptic UlcersView official trial listing → -
Completed NCT NCT00153660
Celecoxib Versus Naproxen for Prevention of Recurrent Ulcer Bleeding in Arthritis Patients
Not yet reported Chinese University of Hong Kong 514 participants Est. completion 2016-12 1 siteCardiovascular disease Other conditions: Arthritis, Cerebrovascular DisordersView official trial listing → -
Completed NCT NCT00157872
A Study of Rofecoxib Versus Naproxen in the Treatment of Chinese Patient With Rheumatoid Arthritis (0966-231)
Not yet reported Merck Sharp & Dohme LLC 150 participants Est. completion 2004-09-19Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00170898
Safety and Efficacy of Lumiracoxib Versus Naproxen in Acute Musculoskeletal Pain
Not yet reported Novartis 419 participants 1 siteOther conditions: Musculoskeletal PainView official trial listing → -
Completed NCT NCT00175032
A Comparison of Safety and Treatment in Subjects With Osteoarthritis Taking Low Dose Aspirin
Not yet reported Takeda 1045 participants Est. completion 2004-07Osteoarthritis Other conditions: Peptic UlcerView official trial listing → -
Completed NCT NCT00211549
An Effectiveness and Safety Study of IDEA-033 in Comparison to Oral Naproxen and Placebo for the Treatment of Osteoarthritis of the Knee
Not yet reported IDEA AG 875 participants 100 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00222976
Oral vs Rectal Admin of Naproxen for Post-Vag Perineal Pain Control
Not yet reported University of Saskatchewan 60 participants Est. completion 2007-05 1 siteOther conditions: Post-Vaginal Delivery Perineal PainView official trial listing → -
Completed NCT NCT00240617
Study Of Treximet, Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks
Not yet reported GlaxoSmithKline 623 participants Est. completion 2006-06 52 sitesOther conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT00240630
Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as Trexima, In The Acute Treatment Of Multiple Migraine Attacks
Not yet reported GlaxoSmithKline 646 participants Est. completion 2006-06 50 sites Stand-aloneOther conditions: Migraine Disorders, MigraineView official trial listing → -
Completed NCT NCT00240773
A Safety and Effectiveness Study of Acetaminophen (4000 mg/Day) and Naproxen (750 mg/Day) in the Treatment of Osteoarthritis of the Hip or Knee
Not yet reported Johnson & Johnson Consumer and Personal Products Worldwide 581 participants Est. completion 2003-06OsteoarthritisView official trial listing → -
Completed NCT NCT00261586
A Safety Trial to Compare Different Analgesics in Combination With Low Dose Aspirin to Study Their Bleeding Properties and Their Effects on the Stomach
Not yet reported Johnson & Johnson Consumer and Personal Products Worldwide 92 participants Est. completion 2004-03Other conditions: AnalgesicsView official trial listing → -
Completed NCT NCT00265304
A Long-Term Safety Study of IDEA-033 in Comparison to Oral Naproxen for the Treatment of Osteoarthritis of the Knee
Not yet reported IDEA AG 550 participants 93 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00279747
A One Year Double-blind Trial to Investigate the Efficacy and Safety of Meloxicam Oral Suspension in Juvenile Rheumatoid Arthritis (JRA/JIA)
Not yet reported Boehringer Ingelheim 226 participants Est. completion 2003-01 34 sitesOther conditions: Arthritis, Juvenile RheumatoidView official trial listing → -
Completed NCT NCT00285649
Predicting Patients' Response to Spinal Manipulation
Not yet reported Palmer College of Chiropractic 192 participants Est. completion 2007-03 1 siteOther conditions: Low Back PainView official trial listing → -
Completed NCT NCT00303017
Safety, Efficacy and Acceptability of Flavocoxid (Limbrel)A Pilot Study
Not yet reported Primus Pharmaceuticals 60 participants Est. completion 2006-09 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT00329355
Menstrual Migraine Treatment With TREXIMET (Formerly Known as TREXIMA)
Not yet reported GlaxoSmithKline 351 participants Est. completion 2006-11 35 sitesOther conditions: Migraine, Migraine DisordersView official trial listing → -
Completed NCT NCT00329459
Treximet (Sumatriptan/Naproxen Sodium), Formerly Known as TREXIMA, for Menstrual Migraine in Women With Dysmenorrhea
Not yet reported GlaxoSmithKline 320 participants Est. completion 2006-11 34 sites Stand-aloneOther conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT00346216
Prospective Randomized Evaluation Of Celecoxib Integrated Safety Vs Ibuprofen Or Naproxen
Not yet reported Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 24081 participants Est. completion 2016-04-12 1066 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00350155
Video Capsule Endoscopy to Investigate the Safety and Tolerability of Lumiracoxib in the Small Bowel
Not yet reported Novartis 150 participants 2 sitesOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT00366262
Study Evaluating the Gastrointestinal Safety of PLA-695 Compared to Placebo and Naproxen
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer Est. completion 2007-03 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00367211
Study to Evaluate the Incidence of Gastric Ulcers Following Administration of Either PN 200 or Naproxen in Subjects Who Are at Risk for Developing NSAID-Associated Ulcers.
Not yet reported POZEN 400 participants Est. completion 2007-09 1 siteOsteoarthritis Other conditions: Rheumatoid Arthritis, Ankylosing SpondylitisView official trial listing → -
Completed NCT NCT00382993
A Study of Combination Product (Sumatriptan Succinate and Naproxen Sodium) in Migraine Subjects Who Report Poor Response or Intolerance to Short Acting Triptans (Study 2 of 2)
Not yet reported GlaxoSmithKline 169 participants Est. completion 2007-11 28 sitesOther conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT00383162
A Study of Combination Product (Sumatriptan Succinate and Naproxen Sodium) in Migraine Subjects Who Report Poor Response or Intolerance to Short Acting Triptans (Study 1 of 2)
Not yet reported GlaxoSmithKline 173 participants Est. completion 2007-10 26 sitesOther conditions: Migraine DisordersView official trial listing → -
Terminated NCT NCT00383487
A Phase II Trial of Calcitriol and Naproxen in Patients With Recurrent Prostate Cancer
Not yet reported Stanford University 20 participants Est. completion 2007-07 1 siteOther conditions: Prostatic Neoplasms, Prostate CancerView official trial listing → -
Completed NCT NCT00385008
TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine
Not yet reported GlaxoSmithKline 20 participants Est. completion 2006-11-24 1 siteOther conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT00387881
TREXIMET (Formerly Known as TREXIMA) for the Acute Treatment of Probable Migraine (ICHD-II 1.6.1)
Not yet reported GlaxoSmithKline 679 participants Est. completion 2008-02 70 sites Stand-aloneOther conditions: Migraine, Without AuraView official trial listing → -
Completed NCT NCT00392080
A Study Of The Effect Of CJ-023,423 On The Incidence Of Stomach Ulcers
Not yet reported Pfizer 340 participants Est. completion 2008-02 11 sitesOsteoarthritisView official trial listing → -
Terminated NCT NCT00396955
A Study Comparing 4 Dose Regimens of PLA-695, Naproxen, and Placebo In Subjects With Osteoarthritis Of The Knee
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 560 participants Est. completion 2007-11 83 sitesOsteoarthritisView official trial listing → -
Terminated NCT NCT00410995
Effects of Naproxen on Physical Performance
Not yet reported University of Oklahoma 40 participants Est. completion 2006-08 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT00418782
A Study Of The Effect Of CE-224535 On Knee OA (Osteoarthritis) Pain
Not yet reported Pfizer 212 participants Est. completion 2007-08 46 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00433732
To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migraine Headaches
Not yet reported POZEN 1400 participants Est. completion 2005-04 2 sitesOther conditions: Migraine HeadachesView official trial listing → -
Completed NCT NCT00434083
To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migrane Headaches
Not yet reported POZEN 1200 participants Est. completion 2005-01 2 sitesOther conditions: Migraine HeadachesView official trial listing → -
Completed NCT NCT00435292
Study of Flavocoxid (Limbrel) vs Naproxen in Subjects With Mod-Severe Osteoarthritis of the Knee
Not yet reported Primus Pharmaceuticals 350 participants Est. completion 2007-12 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT00442208
An Open-Label, Randomized, Comparative 3-Way Cross-Over Study to Evaluate the Effect of Food on the 24-Hour Intragastric pH at Day 5 After Twice Daily Oral Administration of PN 200 (Omeprazole/Naproxen) in Healthy Volunteers
Not yet reported POZEN 24 participants Est. completion 2008-02 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00442221
The Safety Of Combo Formulation In The Treatment Of Multiple Episodes Of Acute Migraine Over 12 Months
Not yet reported POZEN 500 participants Est. completion 2004-08 2 sitesOther conditions: Migraine HeadachesView official trial listing → -
Completed NCT NCT00447486
A Study of GW842166 in Adults With Osteoarthritis Pain
Not yet reported GlaxoSmithKline 308 participants 22 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00447759
The Standard Care Versus Celecoxib Outcome Trial
Not yet reported University of Dundee 7297 participants Est. completion 2015-08 10 sitesOsteoarthritis Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00449787
Comparing Naproxen to Sumatriptan for Emergency Headache Patients
Not yet reported Montefiore Medical Center 401 participants Est. completion 2009-07 2 sitesOther conditions: Migraine, Tension-type Headache, Primary Headache DisorderView official trial listing → -
Completed NCT NCT00488514
Long-Term Safety of Treximet (Sumatriptan/Naproxen Sodium) for Migraine in Adolescents
Not yet reported GlaxoSmithKline 656 participants Est. completion 2009-08-20 77 sitesOther conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT00503828
Derris Scandens Benth Extract VS Naproxen in Knee OA
Not yet reported Mahidol University 120 participants Est. completion 2009-03 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT00504127
Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee
Not yet reported NicOx 1020 participants 73 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00527787
Evaluating PN 400 (VIMOVO) in Reducing Gastric Ulcers Compared to Non-steroidal Antiinflammatory Drug (NSAID) Naproxen
Not yet reported POZEN 434 participants Est. completion 2008-10 1 siteOther conditions: Gastric UlcerView official trial listing → -
Completed NCT NCT00527904
A 12-month, Phase 3, Open-label, Multi-center Study to Evaluate the Long-term Safety of PN400 (VIMOVO)
Not yet reported POZEN 239 participants Est. completion 2009-03 1 siteOther conditions: Gastric UlcerView official trial listing → -
Completed NCT NCT00536068
Platelet Inhibition by Aspirin, Acetaminophen and NSAID
Not yet reported Kantonsspital Graubünden 11 participants Est. completion 2007-08 1 siteOther conditions: HemostasisView official trial listing → -
Completed NCT NCT00541489
Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Hip
Not yet reported NicOx 800 participants 48 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00542555
Analgesic Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee
Not yet reported NicOx 918 participants Est. completion 2007-09OsteoarthritisView official trial listing → -
Completed NCT NCT00573170
TREXIMET® Versus Butalbital-containing Combination Medications for the Acute Treatment of Migraine in Adults
Not yet reported GlaxoSmithKline 375 participants Est. completion 2009-08 107 sitesOther conditions: Migraine Disorders, Migraine, AcuteView official trial listing → -
Completed NCT NCT00584870
RN624 In Adult Patients With Chronic Low Back Pain
Not yet reported Pfizer 220 participants Est. completion 2008-09-02 38 sitesOther conditions: Low Back PainView official trial listing → -
Withdrawn NCT NCT00586365
Naproxen for the Prevention of HO After Complex Elbow Trauma
Not yet reported Massachusetts General Hospital Est. completion 2010-10 1 siteOther conditions: Heterotopic OssificationView official trial listing → -
Terminated NCT NCT00594854
Evaluating PN 400 (VIMOVO) in Reducing Gastric Ulcers in High Risk Subjects Compared to Arthrotec
Not yet reported POZEN 20 participants Est. completion 2008-09 1 siteOther conditions: Gastric UlcerView official trial listing → -
Completed NCT NCT00596245
Open-Label, Placebo-Controlled, Parallel Group Study in Healthy Volunteers to Evaluate the Effects of Two Single MT 400 or Naproxen Sodium Tablets
Not yet reported GlaxoSmithKline 42 participants Est. completion 2007-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00599404
PK Study to Evaluate Esomeprazole Plasma Levels Following Administration of PN 400
Not yet reported POZEN 18 participants Est. completion 2008-02Other conditions: HealthyView official trial listing → -
Completed NCT NCT00601458
Bunionectomy Study (0000-063)
Not yet reported Merck Sharp & Dohme LLC 100 participants Est. completion 2008-01Other conditions: Acute PainView official trial listing → -
Completed NCT NCT00602420
Prevention of Pegfilgrastim-Induced Bone Pain (PIBP)
Not yet reported Gary Morrow 510 participants Est. completion 2012-03 16 sitesOther conditions: Musculoskeletal Complications, Pain, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00602901
Elderly Back Pain: Comparing Chiropractic to Medical Care
Not yet reported Palmer College of Chiropractic 240 participants Est. completion 2007-03 2 sitesOther conditions: Subacute Low Back Pain, Chronic Low Back PainView official trial listing → -
Status unknown NCT NCT00615875
Naproxen for Acute Pain After Surgery: A Randomized, Placebo-Controlled Trial
Not yet reported Hamilton Health Sciences Corporation 24 participants Est. completion 2008-06 1 siteOther conditions: Pain, PostoperativeView official trial listing → -
Completed NCT NCT00621881
A Phase 1 Study to Compare the PK and Safety of Naproxcinod in Hepatic Impaired Patients and Matching Healthy Subjects
Not yet reported NicOx 24 participants 1 siteOther conditions: Liver DiseaseView official trial listing → -
Completed NCT NCT00626275
Study Evaluating the Analgesic Efficacy and Safety of ADL5859 in Participants With Rheumatoid Arthritis
Not yet reported Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 46 participants Est. completion 2008-09 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00638807
Safety and Efficacy of Celecoxib Versus Placebo in the Treatment of Knee Osteoarthritis in Patients Who Were Unresponsive to Naproxen and Ibuprofen
Not yet reported Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 388 participants Est. completion 2004-07 33 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00640627
Efficacy and Safety of Celecoxib Versus Placebo in the Treatment of Patients With Osteoarthritis of the Knee Who Were Unresponsive to Naproxen and Ibuprofen
Not yet reported Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 380 participants Est. completion 2004-09 30 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00643799
Safety and Efficacy of Celecoxib Versus Naproxen in the 6-month Treatment of Knee Osteoarthritis
Not yet reported Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 586 participants Est. completion 2005-01 51 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00648258
A Double-Blind, Double Dummy, Randomized Comparison Study Of The Efficacy And Safety Of Valdecoxib 10mg Once Daily And Naproxen 500mg Twice Daily In Treating The Signs And Symptoms Of Osteoarthritis Of The Knee Or Hip In Taiwan
Not yet reported Pfizer 130 participants Est. completion 2004-04 4 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00650455
Efficacy and Safety of Valdecoxib and Naproxen in Treating the Signs and Symptoms of Rheumatoid Arthritis (RA) in a Severe Rheumatoid Arthritis Patients
Not yet reported Pfizer 489 participants Est. completion 2005-01 55 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00652808
Double-Blind, Double Dummy, Randomized Comparison Study to Evaluate the Efficacy and Safety of Valdecoxib 10 mg Once Daily and Naproxen 500 mg Twice Daily in Treating the Signs and Symptoms of Osteoarthritis of the Knee
Not yet reported Pfizer 265 participants Est. completion 2004-09 8 sitesOsteoarthritis Other conditions: KneeView official trial listing → -
Completed NCT NCT00652925
A Study to Evaluate the Efficacy and Safety of Celecoxib Suspension Compared to Naproxen Suspension in Patients With JRA
Not yet reported Pfizer 225 participants Est. completion 2005-04 58 sitesOther conditions: Arthritis, Juvenile RheumatoidView official trial listing → -
Completed NCT NCT00659490
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1940
Not yet reported AstraZeneca 151 participants Est. completion 2008-05 1 siteOther conditions: PainView official trial listing → -
Completed NCT NCT00662610
A Study to Assess the Effects of Naproxcinod and Naproxen on Blood Pressure Measurements in Osteoarthritis Patients With Controlled High Blood Pressure
Not yet reported NicOx 120 participants Est. completion 2008-11 29 sitesOsteoarthritis Other conditions: HypertensionView official trial listing → -
Completed NCT NCT00662896
To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension
Not yet reported NicOx 300 participants Est. completion 2008-12 57 sitesOsteoarthritis Other conditions: HypertensionView official trial listing → -
Completed NCT NCT00664560
Efficacy Study of PN400 (VIMOVO) Twice Daily and Celebrex Once Daily in Patients With Osteoarthritis
Not yet reported POZEN 614 participants Est. completion 2009-01 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT00665431
Efficacy Study of PN400 (VIMOVO) Twice Daily and Celebrex Once Daily in Patients With Osteoarthritis
Not yet reported POZEN 610 participants Est. completion 2009-01 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT00665743
Study Evaluating the Bioavailability of Naproxen 500 mg in Three Formulations
Not yet reported POZEN 30 participants Est. completion 2008-06 1 siteOther conditions: ArthritisView official trial listing → -
Completed NCT NCT00672646
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1386
Not yet reported AstraZeneca 103 participants Est. completion 2008-06 1 siteOther conditions: PainView official trial listing → -
Completed NCT NCT00674856
A Pharmacokinetics and Safety Study of Naproxcinod in Subjects With Impaired Renal Function
Not yet reported NicOx 32 participants Est. completion 2008-10 3 sitesOther conditions: Renal FailureView official trial listing → -
Completed NCT NCT00676442
Study Evaluating the Effect of Food on the Bioavailability of PN400 Components
Not yet reported POZEN 24 participants Est. completion 2008-06 1 siteOther conditions: ArthritisView official trial listing → -
Completed NCT NCT00692016
Fast & Fed Pharmacokinetic (PK) Study
Not yet reported Bayer 32 participants Est. completion 2008-03 1 siteOther conditions: BioavailabilityView official trial listing → -
Completed NCT NCT00692055
Study Evaluating the Bioavailability of Naproxen 375 mg in Two Formulations
Not yet reported POZEN 30 participants Est. completion 2008-07 1 siteOther conditions: ArthritisView official trial listing → -
Completed NCT NCT00720057
Assessing the Analgesic Efficacy of Naproxen Sodium in Postsurgical Dental Pain.
Not yet reported Bayer 312 participants Est. completion 2008-08 3 sites Stand-aloneOther conditions: ToothacheView official trial listing → -
Completed NCT NCT00743587
A Study To Assess The Ability Of Tramadol, Naproxen And Oxycodone To Affect The Pain Thresholds Of Patients With Osteoarthritis Of The Thumb
Not yet reported Pfizer 36 participants Est. completion 2009-03 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT00749385
A Pharmacokinetic (PK) Study Evaluating Naproxen and Esomeprazole Plasma Levels
Not yet reported POZEN 40 participants Est. completion 2008-10 1 siteOther conditions: ArthritisView official trial listing → -
Completed NCT NCT00750243
Comparator Study of LT-NS001 in Healthy Subjects With Endoscopic Evaluation
Not yet reported Logical Therapeutics 120 participants Est. completion 2009-04 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00751400
Naproxen Sodium Extended-Release Actual Use Study
Not yet reported Bayer 497 participants Est. completion 2008-11 24 sites Stand-aloneOther conditions: PainView official trial listing → -
Completed NCT NCT00751556
Single/Multiple Dose Bioavailability Trial
Not yet reported Bayer 32 participants Est. completion 2008-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00761501
Phase I Study to Evaluate Bioavailability of Naproxen as PN400 Compared to Naproxen as Proxen S and Naprosyn E
Not yet reported AstraZeneca 38 participants Est. completion 2008-12 2 sitesOther conditions: Healthy VolunteerView official trial listing → -
Completed NCT NCT00772967
A Study to Evaluate the Effect of Analgesics on a Walking Model of Knee Pain (0000-105)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 22 participants Est. completion 2008-11OsteoarthritisView official trial listing → -
Completed NCT NCT00778193
Effect of Naproxen, Aspirin, Celecoxib, or Clopidogrel on the Healing of Stomach and Intestinal Ulcers
Not yet reported Research Associates of New York, LLP 125 participants Est. completion 2008-03 1 siteOther conditions: Gastroduodenal UlcerView official trial listing → -
Terminated NCT NCT00780325
Effects of Dual Cyclooxygenase-2 and Carbonic Anhydrase Inhibition
Not yet reported University of Pennsylvania 26 participants Est. completion 2013-07 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT00789802
A Randomized Controlled Trial of Oral Naproxen and Transdermal Estradiol for Bleeding in LNG-IUC
Not yet reported Washington University School of Medicine 129 participants Est. completion 2011-01 1 siteOther conditions: Contraception, BleedingView official trial listing → -
Completed NCT NCT00790985
Efficacy of Flavocoxid 500 mg Compared With Naproxen 500 mg in Subjects With Moderate-severe Osteoarthritis of the Knee
Not yet reported Primus Pharmaceuticals 223 participants Est. completion 2008-08OsteoarthritisView official trial listing → -
Completed NCT NCT00792636
A Study to Determine the Effect of Sumatriptan and Naproxen Sodium Combination Tablet, Sumatriptan Tablet, and Naproxen Sodium Tablet on Blood Pressure When Treating Migraine Headaches That Occur During a 6-month Period
Not yet reported GlaxoSmithKline 407 participants Est. completion 2009-11 49 sites Stand-aloneOther conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT00803764
Bioequivalence Study Between Two Oral Formulations of Naproxen 500 mg Tablets Under Fed Conditions
Not yet reported Perrigo Company 34 participantsOther conditions: BioequivalencyView official trial listing → -
Completed NCT NCT00804401
Bioequivalence Study Between Two Oral Formulations of Naproxen 500 mg Tablets Under Fasting Conditions
Not yet reported Perrigo Company 34 participantsOther conditions: BioequivalencyView official trial listing → -
Completed NCT NCT00807846
A Study To Evaluate The Effects Of Celecoxib (Celebrex®) Or Naproxen On Blood Pressure In Pediatric Subjects
Not yet reported Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 201 participants Est. completion 2012-12 39 sitesOther conditions: Arthritis, Juvenile RheumatoidView official trial listing → -
Terminated NCT NCT00809354
Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip
Not yet reported Pfizer 2720 participants Est. completion 2011-01-12 333 sitesOsteoarthritis Other conditions: ArthritisView official trial listing → -
Completed NCT NCT00818415
Naproxen Sodium ER Pharmacokinetic Study
Not yet reported Bayer 32 participants Est. completion 2008-11 1 site Stand-aloneOther conditions: PainView official trial listing → -
Completed NCT NCT00826462
Treatment Study of Steroid Injection and Physical Therapy for Acute Lateral Epicondylitis
Not yet reported University of Oslo 177 participants Est. completion 2013-06 1 siteOther conditions: Tennis Elbow, Epicondylitis, Lateral HumeralView official trial listing → -
Completed NCT NCT00830050
Brain Imaging To Examine The Effect Of Naproxen In Hand Osteoarthritis Patients
Not yet reported Pfizer 24 participants Est. completion 2010-12 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT00830063
Tanezumab In Osteoarthritis Of The Knee (2)
Not yet reported Pfizer 832 participants Est. completion 2010-08-31 94 sitesOsteoarthritis Other conditions: ArthritisView official trial listing → -
Status unknown NCT NCT00837044
Treximet in Acute Migraine Headache: Assessing Cognitive Function
Not yet reported Neurological Research Center 30 participants Est. completion 2009-09 1 siteOther conditions: Migraine Headache, Cognitive ImpairmentView official trial listing → -
Completed NCT NCT00843024
Migraine Study in Adolescent Patients
Not yet reported GlaxoSmithKline 589 participants Est. completion 2010-06 79 sites Stand-aloneOther conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT00844805
Infliximab for Treatment of Axial Spondyloarthritis (P05336 AM1)
Not yet reported Merck Sharp & Dohme LLC 158 participants Est. completion 2011-09Other conditions: Ankylosing Spondylitis, Axial SpondyloarthritisView official trial listing → -
Completed NCT NCT00863304
Tanezumab in Osteoarthritis of the Hip or Knee (2)
Not yet reported Pfizer 849 participants Est. completion 2010-08-16 95 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00875784
An Open-label, Randomized, 3-period Crossover Study to Evaluate Sumatriptan Pharmacokinetics for a TREXIMA™ (Sumatriptan Succinate / Naproxen Sodium) Tablet Followed by IMITREX® (Sumatriptan Succinate)
Not yet reported GlaxoSmithKline 30 participants Est. completion 2008-06-14 1 site Stand-aloneOther conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT00876187
A Study of Tanezumab in Adults With Chronic Low Back Pain
Not yet reported Pfizer 1359 participants Est. completion 2011-02-01 135 sitesOther conditions: Low Back PainView official trial listing → -
Status unknown NCT NCT00893594
Efficacy of Sumatriptan With Naprosyn in Migraine With Aura
Not yet reported Dent Neurologic Institute 30 participants Est. completion 2015-12 1 siteOther conditions: Migraine With AuraView official trial listing → -
Completed NCT NCT00893737
"Completeness of Response" Following Treatment With Treximet™ for Migraine
Not yet reported Cady, Roger, M.D. 147 participants Est. completion 2010-01 8 sites Stand-aloneOther conditions: MigraineView official trial listing → -
Completed NCT NCT00907400
Phase I Study to Evaluate Bioavailability of Naproxen as PN400 Compared to Naproxen as Naprosyn E
Not yet reported AstraZeneca 48 participants Est. completion 2009-09 2 sitesOther conditions: HealthyView official trial listing → -
Completed NCT NCT00909519
Effect of Repeated Dosing of Naproxcinod on Renal Hemodynamic and on Sodium Balance in Healthy Volunteers Before and After a Single Dose of Furosemide
Not yet reported NicOx 31 participants Est. completion 2009-04Other conditions: Renal HemodynamicsView official trial listing → -
Completed NCT NCT00913627
Study Evaluating Ibuprofen 600 mg Extended Release (ER) For Dental Pain
Not yet reported Pfizer 196 participants Est. completion 2009-08-05 1 siteOther conditions: PainView official trial listing → -
Completed NCT NCT00928837
Study of Flavocoxid (Limbrel) Versus Naproxen in Subjects With Moderate-Severe Osteoarthritis of the Knee
Not yet reported Primus Pharmaceuticals 350 participants Est. completion 2007-09 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT00933582
A Clinical Study to Investigate the Effect on Pain Relief of a Single Dose of JNJ-39439335 in Patients With Chronic Osteoarthritis Pain of the Knee
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 33 participants Est. completion 2010-06OsteoarthritisView official trial listing → -
Terminated NCT NCT00945178
Double-blind Placebo-controlled 2-part Study Assessing the Safety, Tolerability and PK of AZD1386 in Healthy Volunteers
Not yet reported AstraZeneca 11 participants Est. completion 2009-09 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT00959439
Relative Bioavailability Study of Naproxen Delayed-Release Tablets (375 mg)
Not yet reported Sandoz 34 participants Est. completion 2002-05Osteoarthritis Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00966641
Oral Bioequivalence Study of PL 3100 and Naproxen in Healthy Adults
Not yet reported, Not yet reported PLx Pharma 34 participants Est. completion 2009-10 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT00969449
Pharmacokinetics Study Comparing Naproxen Sodium Extended Release and Naprelan
Not yet reported Bayer 28 participants Est. completion 2009-05 1 site Stand-aloneOther conditions: PharmacokineticsView official trial listing → -
Completed NCT NCT00981357
A Study To Investigate Whether PF-04457845 Is Effective In Treating Pain, Is Safe And Tolerable In Patients With Osteoarthritis Of The Knee
Not yet reported Pfizer 76 participants Est. completion 2010-05 7 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT00989625
A Pharmacokinetic Study to Evaluate TREXIMET in Adolescents With Migraine and Healthy Subjects Administered at Three Doses.
Not yet reported GlaxoSmithKline 50 participants Est. completion 2009-09-10 3 sitesOther conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT00992381
Comparison Study of a New Combination of 2 Marketed Medications (Esomeprazole and Naprosyn) Versus Naprosyn Alone
Not yet reported AstraZeneca 24 participants Est. completion 2009-10 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01003639
Idiopathic Intracranial Hypertension Treatment Trial
Not yet reported, Not yet reported St. Luke's-Roosevelt Hospital Center 165 participants Est. completion 2014-01 41 sitesOther conditions: Idiopathic Intracranial HypertensionView official trial listing → -
Completed NCT NCT01016678
Treximet Early Intervention Adolescent Migraine
Not yet reported, Not yet reported Premiere Research Institute 104 participants Est. completion 2014-07 4 sitesOther conditions: MigraineView official trial listing → -
Completed NCT NCT01052129
Bioequivalence Study of Naproxen Sodium 550 mg Tablets Under Fasting Condition
Not yet reported Dr. Reddy's Laboratories Limited 26 participants Est. completion 2006-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01052792
Bioequivalence Study of Naproxen Sodium 550 mg Tablets Under Fed Conditions
Not yet reported Dr. Reddy's Laboratories Limited 26 participants Est. completion 2006-06 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT01053507
Treximet for Prevention of Post Traumatic Headache Associated With Cognitive Dysfunction
Not yet reported Cady, Roger, M.D. 23 participants Est. completion 2012-11 3 sitesOther conditions: Post-Traumatic HeadacheView official trial listing → -
Completed NCT NCT01059604
Sumatriptan and Naratriptan Pregnancy Registry
GlaxoSmithKline 868 participants Est. completion 2013-04Other conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT01063920
Rates of Gastric Ulcer by Endoscopy in Knee Osteoarthritis Patients Receiving LT-NS001 Versus Naprosyn®
Not yet reported, Not yet reported Logical Therapeutics 534 participants Est. completion 2010-11 65 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT01071317
Trial of Comprehensive Migraine Intervention
Not yet reported Montefiore Medical Center 50 participants Est. completion 2012-01 1 siteOther conditions: MigraineView official trial listing → -
Completed NCT NCT01086358
Does Treximet Improve Productivity and Patient Satisfaction Due to Sustained Response and Consistency of Response?
Not yet reported The Cleveland Clinic 60 participants Est. completion 2016-08 1 siteOther conditions: Workplace Migraine TreatmentView official trial listing → -
Completed NCT NCT01090050
Treximet in the Treatment of Chronic Migraine
Not yet reported Cady, Roger, M.D. 56 participants Est. completion 2012-07 2 sitesOther conditions: Chronic MigraineView official trial listing → -
Completed NCT NCT01090596
Changes in mRNA Expression Following Exposure to Naproxen
Not yet reported Research Associates of New York, LLP 48 participants Est. completion 2008-07Other conditions: HealthyView official trial listing → -
Completed NCT NCT01094483
A Study Assessing Inhibition of Serum Thromboxane B2 Levels With PN400 and Low Dose Aspirin
Not yet reported AstraZeneca 40 participants Est. completion 2010-05 1 siteOther conditions: Platelet InhibitionView official trial listing → -
Completed NCT NCT01102660
Clinical Trial to Examine the Pain Relief of PH-797804 Alone Or With Naproxen in Subjects With Osteoarthritis of the Knee
Not yet reported Pfizer 172 participants Est. completion 2011-03 26 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT01107236
Study to Evaluate Efficacy and Safety of IW-6118 in Patients Undergoing Third Molar Extraction
Not yet reported Ironwood Pharmaceuticals, Inc. 90 participants Est. completion 2010-08 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT01112553
Treximet Migraine Brain Imaging Research Study
Mclean Hospital 2 participants Est. completion 2012-10 1 siteOther conditions: Acute MigraineView official trial listing → -
Completed NCT NCT01118273
Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine
Not yet reported Bayer 162 participants Est. completion 2008-02 1 site Stand-aloneOther conditions: SleepView official trial listing → -
Completed NCT NCT01129011
Evaluating PN 400 (VIMOVO) in Reducing Gastric Ulcers Compared to Non-steroidal Antiinflammatory Drug (NSAID) Naproxen
Not yet reported POZEN 420 participants Est. completion 2008-10Other conditions: Gastric UlcerView official trial listing → -
Completed NCT NCT01131728
Bioequivalence Study of Naproxen Sodium 220 mg & Pseudoephedrine HCl 120 mg ER Tablets of Dr. Reddy's Under Fasting Conditions
Not yet reported Dr. Reddy's Laboratories Limited 26 participants Est. completion 2004-09 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01131767
Bioequivalence Study of Naproxen Sodium 220 mg & Pseudoephedrine HCl 120 mg ER Tablets of Dr. Reddy's Under Fed Conditions
Not yet reported Dr. Reddy's Laboratories Limited 26 participants Est. completion 2004-09 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01138150
Ictal and Interictal Inflammatory Markers in Migraine
Not yet reported Johns Hopkins University 36 participants Est. completion 2013-06 1 siteOther conditions: MigraineView official trial listing → -
Completed NCT NCT01139190
Clinical Trial Evaluating Gastrointestinal Damage Following Administration PL3100 or Naproxen in At-Risk Adults
Not yet reported PLx Pharma 77 participants Est. completion 2010-12 2 sitesOther conditions: Gastroduodenal Ulcerations, ErosionView official trial listing → -
Terminated NCT NCT01147458
A Study Of The Safety And Efficacy Of PF-04191834 In Patients With Osteoarthritis Of The Knee
Not yet reported Pfizer 190 participants Est. completion 2011-02 31 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT01154790
Phase I Study on Multiple Oral Dosing of CG100649
Not yet reported CrystalGenomics, Inc. 120 participants Est. completion 2011-01 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01160822
To Determine the Safety, Tolerability, Pharmacokinetics and Effect on Pain of a Single Intra-articular Administration of Canakinumab in Patients With Osteoarthritis in the Knee
Not yet reported Novartis Pharmaceuticals 169 participants Est. completion 2011-07 13 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT01165307
Medical Therapy Versus Radiofrequency Endometrial Ablation in the Initial Treatment of Menorrhagia
Not yet reported Abimbola Famuyide 77 participants Est. completion 2015-10 1 siteOther conditions: MenorrhagiaView official trial listing → -
Completed NCT NCT01165814
Naproxen Versus Tramadol for Post Cesarean Pain Control
Not yet reported Bnai Zion Medical Center 120 participants Est. completion 2009-03 1 siteOther conditions: Pain, Cesarean SectionView official trial listing → -
Completed NCT NCT01178203
The Effects of Three Oral Medications on Post-operative Pain Following Endodontic Treatment
Not yet reported, Not yet reported Azad University of Medical Sciences Est. completion 2010-08Other conditions: Pulpitis, Pain ManagementView official trial listing → -
Completed NCT NCT01207115
A Study of ABT-652 in Adults With Osteoarthritis Pain of the Knee
Not yet reported AbbVie (prior sponsor, Abbott) 322 participants Est. completion 2011-05 38 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT01208207
A Two-Part 26-Week Study of Etoricoxib as Treatment for Ankylosing Spondylitis (AS) (MK-0663-108)
Not yet reported Organon and Co 1015 participants Est. completion 2014-11-12Other conditions: Spondylitis, AnkylosingView official trial listing → -
Completed NCT NCT01229228
Study of Naproxen Capsules to Treat Dental Pain
Not yet reported Iroko Pharmaceuticals, LLC 254 participants Est. completion 2011-04 1 siteOther conditions: Dental PainView official trial listing → -
Completed NCT NCT01231490
Acute Osteoarthritis Experimental Model Study.
Not yet reported GlaxoSmithKline 53 participants Est. completion 2009-03 3 sitesOsteoarthritisView official trial listing → -
Terminated NCT NCT01267825
CT Guided Injection for Low Back Radiculopathy: A Randomized Clinical Trial
Not yet reported Montefiore Medical Center 1 participants Est. completion 2013-08 1 siteObstructive sleep apnea Other conditions: Disc HerniationView official trial listing → -
Terminated NCT NCT01279395
Anti-inflammatory Agents and Cholesterol Metabolism
Winthrop University Hospital 3 participants Est. completion 2018-01-18 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT01280591
Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine in Patients With Postsurgical Dental Pain
Not yet reported Bayer 712 participants Est. completion 2011-02 2 sites Stand-aloneOther conditions: Pain, PostoperativeView official trial listing → -
Completed NCT NCT01300546
Treximet Trademark (TM) in the Prevention and Modification of Disease Progression in Migraine
Not yet reported Cady, Roger, M.D. 40 participants Est. completion 2012-04 2 sitesOther conditions: MigraineView official trial listing → -
Completed NCT NCT01329562
CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After Treximet
Not yet reported Cady, Roger, M.D. 41 participants Est. completion 2012-06 2 sitesOther conditions: Menstrual MigraineView official trial listing → -
Completed NCT NCT01331993
A Bioequivalence Study to Compare VIMOVO Manufactured at AstraZenca AB to VIMOVO Manufactured by Patheon Pharmaceuticals and Marketed Enteric-coated Naproxen Formulation
Not yet reported AstraZeneca 36 participants Est. completion 2011-10 1 siteOther conditions: Healthy Volunteers, BioequivalenceView official trial listing → -
Completed NCT NCT01332500
Treximet ™ Pharmacy Budget Impact Model Database Validation Study
GlaxoSmithKline 61737 participants Est. completion 2010-03Other conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT01343303
A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With Osteoarthritis
Not yet reported Janssen Research & Development, LLC 43 participants Est. completion 2011-12 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT01358383
Assessment of Pharmacokinetics of a Single Oral Dose of VIMOVO in Healthy Adult Volunteers
Not yet reported AstraZeneca 28 participants Est. completion 2011-06 1 siteOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT01365052
Safety Trial of Naproxen Sodium/ Diphenhydramine
Not yet reported Bayer 326 participants Est. completion 2011-07 19 sites Stand-aloneOther conditions: PainView official trial listing → -
Completed NCT NCT01374269
Improvement in Pain,Function and HRQoL ( Health Related Quality of Life) in Subacute Low Back Pain: A Controlled Clinical Trial of Exercise vs NSAIDs (Nonsteroidal Antiinflammatory)
Not yet reported Grupo Rehabilitacion en Salud 90 participants Est. completion 2012-03 2 sitesOther conditions: Back Pain Lower BackView official trial listing → -
Completed NCT NCT01381497
Impact of Migraine on Work Productivity in Patients Treated With a Combination Product Containing Sumatriptan and Naproxen Sodium or Triptan Monotherapy
GlaxoSmithKline 1 participants Est. completion 2011-10Other conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT01381523
A Combination Product of Sumatriptan and Naproxen Sodium Versus Single-entity Oral Triptans: An Analysis of Real World Data
GlaxoSmithKline 1 participants Est. completion 2011-06Other conditions: Migraine DisordersView official trial listing → -
Completed NCT NCT01383486
Self Selection Trial of Naproxen Sodium
Not yet reported Bayer 253 participants Est. completion 2011-08 10 sites Stand-aloneOther conditions: PainView official trial listing → -
Completed NCT NCT01389284
Evaluate Efficacy and Safety of Extended Release (ER) Naproxen Sodium
Not yet reported Bayer 300 participants Est. completion 2011-09 1 site Stand-aloneOther conditions: Pain, PostoperativeView official trial listing → -
Withdrawn NCT NCT01390324
Efficacy and Safety of a Fixed-dose Combination of Naratriptan and Naproxen in Acute Treatment of Migraine
Not yet reported Ache Laboratorios Farmaceuticos S.A. Est. completion 2012-03Other conditions: Migraine, HeadacheView official trial listing → -
Completed NCT NCT01404598
Pharmacokinetics Study: Determination of Naproxcinod and Its Metabolites After Oral Administration in Male
Not yet reported NicOx 24 participants Est. completion 2010-02Other conditions: PharmacokineticsView official trial listing → -
Completed NCT NCT01409603
To Evaluate Whether Naproxen and Darexaban (YM150) Interact in Their Effects
Not yet reported Astellas Pharma Inc 26 participants Est. completion 2010-05 1 siteOther conditions: Pharmacodynamic Interaction, Healthy SubjectsView official trial listing → -
Status unknown NCT NCT01417130
Follow-up Study of the Alzheimer's Disease Anti-Inflammatory Prevention Trial
Seattle Institute for Biomedical and Clinical Research 1650 participants Est. completion 2012-08 6 sitesOther conditions: Alzheimer Disease, DementiaView official trial listing → -
Completed NCT NCT01427803
Actual Use Trial of Naproxen Sodium
Not yet reported Bayer 778 participants Est. completion 2011-12 34 sites Stand-aloneOther conditions: PainView official trial listing → -
Withdrawn NCT NCT01442428
Paradoxical Tuberculosis Immune Reconstitution Inflammatory Syndrome (TB-IRIS) Treatment Trial
Not yet reported, Not yet reported University of Minnesota Est. completion 2016-06 3 sitesOther conditions: Immune Reconstitution Inflammatory Syndrome, Immune Reconstitution Syndrome, Tuberculosis, HIV-infection/AidsView official trial listing → -
Completed NCT NCT01450995
Migraine Treatment Satisfaction With Treximet Versus Concomitant 2 Aleve and Imitrex
Not yet reported Stephen H. Landy, M.D. 50 participants Est. completion 2011-05 1 siteOther conditions: MigraineView official trial listing → -
Completed NCT NCT01468025
Effectiveness of Theramine on Chronic Back Pain
Not yet reported Targeted Medical Pharma 127 participants Est. completion 2009-07Other conditions: Low Back PainView official trial listing → -
Completed NCT NCT01471886
Comparison Of Ketorolac Tromethamine Versus Naproxen For Moderate to Severe Back Pain Treatment
Not yet reported EMS 83 participants Est. completion 2013-11-11 1 siteOther conditions: Back PainView official trial listing → -
Completed NCT NCT01471899
Comparison Of Ketorolac Tromethamine Oral Drops Versus Naproxen For Moderate to Severe Back Pain Treatment
Not yet reported EMS 78 participants Est. completion 2014-04-30Other conditions: Back PainView official trial listing → -
Completed NCT NCT01495858
Evaluate Analgesic / Sedative Efficacy of Naproxen Sodium and Diphenhydramine in Patients With Postsurgical Dental Pain
Not yet reported Bayer 267 participants Est. completion 2012-02 2 sites Stand-aloneOther conditions: Pain, PostoperativeView official trial listing → -
Withdrawn NCT NCT01511627
Randomized Controlled Trial Comparing Postoperative Pain Following TAH With GA vs. Combined GA + SAB
Not yet reported University of Saskatchewan Est. completion 2012-07 1 siteOther conditions: HysterectomyView official trial listing → -
Completed NCT NCT01525043
Study to Evaluate the Efficacy of the Synera Patch Compared to Naproxen Sodium for Epicondylitis of the Elbow
Not yet reported International Clinical Research Institute 78 participants Est. completion 2013-09 1 siteOther conditions: Epicondylitis of the ElbowView official trial listing → -
Completed NCT NCT01539447
Influence of Naproxen on Heterotropic Bone Formation Following Hip Arthroscopy
Not yet reported University of Utah 108 participants Est. completion 2022-03-16 1 siteOther conditions: Heterotopic OssificationView official trial listing → -
Completed NCT NCT01544114
A Safety Study of VIMOVO in Adolescents With Juvenile Idiopathic Arthritis (JIA)
Not yet reported Amgen 46 participants Est. completion 2015-02 17 sitesOther conditions: Juvenile Idiopathic Arthritis (JIA)View official trial listing → -
Status unknown NCT NCT01557816
Trial of Naproxen to Evaluate Various Methods of Measuring Analgesic Effect in Osteoarthritis Pain of the Knee
Not yet reported Analgesic Solutions 70 participants Est. completion 2012-06 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT01587274
A Randomized Study of Three Medication Regimens for Acute Low Back Pain
Not yet reported Montefiore Medical Center 323 participants Est. completion 2014-12 1 siteOther conditions: Acute Low Back PainView official trial listing → -
Terminated NCT NCT01612975
The Effect of Non-Steroidal Anti-Inflammatory Drug Naproxen on Pleural Effusion Formation After Lung Resection
Not yet reported McMaster University 7 participants Est. completion 2018-01 1 siteOther conditions: Pleural Effusion, Pleural Effusion MalignantView official trial listing → -
Completed NCT NCT01638962
The Effect on Knee Joint Loads of Analgesic Use Compared With Exercise in Patients With Knee Osteoarthritis - An RCT
Not yet reported University of Southern Denmark 93 participants Est. completion 2016-07 1 siteOsteoarthritisView official trial listing → -
Status unknown NCT NCT01659372
Low Level Laser Therapy Versus Pharmacotherapy in in Improving Masticatory Muscle Pain
Not yet reported Shahid Beheshti University 40 participants Est. completion 2013-03 2 sitesOther conditions: TMDView official trial listing → -
Completed NCT NCT01666678
Compare Pharmacokinetic (PK) Profiles of Naproxen Sodium, Diphenhydramine Hydrochloride, and Naproxen Sodium and Diphenhydramine Hydrochloride Combination
Not yet reported Bayer 32 participants Est. completion 2012-03 1 site Stand-aloneOther conditions: Therapeutic EquivalenceView official trial listing → -
Completed NCT NCT01670552
Evaluation of Two Therapies for the Treatment of Osteoarticular Inflammation in Dyspeptic Patients
Not yet reported EMS 490 participants Est. completion 2017-03-17 1 siteOther conditions: Acute and Chronic Inflammation, DyspepsiaView official trial listing → -
Completed NCT NCT01688934
Analgesic Efficacy and Safety of V116517 in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis (OA) of the Knee
Not yet reported Purdue Pharma LP 230 participants Est. completion 2013-08 18 sitesOsteoarthritis Other conditions: PainView official trial listing → -
Completed NCT NCT01712009
NOLAN: Naproxen or Loratadine and Neulasta
Not yet reported Amgen 600 participants Est. completion 2015-03-18 83 sitesOther conditions: Bone Pain in Stage I - III Breast CancerView official trial listing → -
Withdrawn NCT NCT01726920
Efficacy and Safety of a Fixed-dose Combination of Naratriptan and Naproxen in Acute Treatment of Migraine.
Not yet reported Ache Laboratorios Farmaceuticos S.A.Other conditions: Migraine, HeadacheView official trial listing → -
Completed NCT NCT01884272
NSAID Drug Interaction Study
Not yet reported Ardea Biosciences, Inc. 24 participants Est. completion 2013-10 1 siteOther conditions: GoutView official trial listing → -
Completed NCT NCT01916395
Comparison of Treximet & Imitrex as They Affect the Levels of Inflammatory Markers When the Patient is Actively Having a Migraine Headache
Gary E. Ruoff, M.D. 30 participants Est. completion 2011-07 1 siteOther conditions: MigraineView official trial listing → -
Completed NCT NCT01939002
Characterize Flu-like Symptoms in Relapsing Multiple Sclerosis Patients Transitioning From Non-Pegylated Interferon Beta (IFN-β) Therapies to Peginterferon Beta-1a (BIIB017)
Not yet reported Biogen 251 participants Est. completion 2015-11 38 sitesOther conditions: Relapsing Multiple SclerosisView official trial listing → -
Completed NCT NCT01951105
Effect of L-dopa In Subacute Back Pain Population
Not yet reported Northwestern University 72 participants Est. completion 2017-09-25 1 siteOther conditions: Sub-acute Back PainView official trial listing → -
Completed NCT NCT01952652
Naproxen Codeine in Arthroscopic Surgery
Not yet reported Baskent University 61 participants Est. completion 2013-07 1 siteOther conditions: Arthroscopic Meniscus SurgeryView official trial listing → -
Withdrawn NCT NCT01982799
Local Anesthesia and Analgesics in Endodontic Pain
Not yet reported University of Minnesota Est. completion 2015-09 1 siteOther conditions: OdontalgiaView official trial listing → -
Completed NCT NCT01994226
Colchicine Or Naproxen Treatment for ACute gouT
Not yet reported Keele University 399 participants Est. completion 2016-03 1 siteOther conditions: GoutView official trial listing → -
Completed NCT NCT01995006
Effect of Metamizole (Dipyrone) on Renal Function in Salt-depleted Healthy Subjects
Not yet reported University Hospital, Basel, Switzerland 15 participants Est. completion 2014-04 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02013427
Placebo In Chronic Back Pain - Double-Blind Randomized Control Trial
Not yet reported Northwestern University 82 participants Est. completion 2016-05 1 siteOther conditions: Chronic Low Back PainView official trial listing → -
Completed NCT NCT02052908
Naproxen in Preventing DNA Mismatch Repair Deficient Colorectal Cancer in Patients With Lynch Syndrome
Not yet reported National Cancer Institute (NCI) 81 participants Est. completion 2021-01-05 4 sitesOther conditions: Lynch SyndromeView official trial listing → -
Withdrawn NCT NCT02094807
Pain as Indication for Operative Treatment of Traumatic Rib Fractures
Not yet reported Sahlgrenska University Hospital Est. completion 2020-01 1 siteOther conditions: Trauma, Rib Fractures, Surgery, PainView official trial listing → -
Terminated NCT NCT02108548
A Study to Assess the Safety and Tolerability, Including Gastrointestinal Safety, Pharmacokinetics and Pharmacodynamics of ASP7657 in Caucasian Healthy Male and Female Subjects
Not yet reported Astellas Pharma Europe B.V. 89 participants Est. completion 2015-03 1 siteOther conditions: Pharmacokinetics of ASP7657, Pharmacodynamics of ASP7657, Healthy SubjectsView official trial listing → -
Withdrawn NCT NCT02116790
Efficacy of Co-administration of an NSAID With a Dopamine Agonist In Healthy Subjects
Not yet reported Northwestern University Est. completion 2015-01Other conditions: Acute PainView official trial listing → -
Completed NCT NCT02128490
Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout and Moderate Renal Impairment
Not yet reported Takeda 189 participants Est. completion 2015-10 89 sitesOther conditions: Gout, Moderate Renal ImpairmentView official trial listing → -
Completed NCT NCT02132416
Operative Treatment of Unstable Thoracic Cage Injuries and Chest Wall Deformity in Trauma
Not yet reported Sahlgrenska University Hospital 92 participants Est. completion 2018-12 2 sitesOther conditions: Trauma, Flail Chest, Rib Fractures, SurgeryView official trial listing → -
Completed NCT NCT02139046
Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout
Not yet reported Takeda 1790 participants Est. completion 2015-11 192 sitesOther conditions: GoutView official trial listing → -
Completed NCT NCT02152592
Controlled-Release Oxycodone Versus Naproxen at Home After Ambulatory Surgery: A Randomized Controlled Trial
Not yet reported Maastricht University Medical Center 105 participants 1 siteOther conditions: Postoperative Pain After Ambulatory SurgeryView official trial listing → -
Completed NCT NCT02183038
Efficacy and Safety of Meloxicam vs. Naproxen Sodium in Patients With Acute Non Bacterial Pharyngitis or Pharyngo-tonsillitis
Not yet reported Boehringer Ingelheim 390 participants Stand-aloneOther conditions: PharyngitisView official trial listing → -
Completed NCT NCT02202512
Effect of Repeated Doses of BI 1060469 and BI 1021958 on Glomerular Filtration Rate (GFR) in Healthy Volunteers
Not yet reported Boehringer Ingelheim 53 participants Est. completion 2014-12 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02229461
Naproxen Sodium/ASA Platelet Study
Not yet reported Bayer 117 participants Est. completion 2015-05 1 site Stand-aloneOther conditions: HematologyView official trial listing → -
Status unknown NCT NCT02252614
Efficacy of Intravenous Naproksen Sodium+Codein and Paracetamol+Codein on Postoperative Pain on Postoperative Pain
Not yet reported Diskapi Yildirim Beyazit Education and Research Hospital 75 participants Est. completion 2014-12Other conditions: Postoperative Pain, PCA Contramal ConsumptionView official trial listing → -
Status unknown NCT NCT02255955
Postoperative Analgesia in Laminectomy
Not yet reported Diskapi Yildirim Beyazit Education and Research Hospital 75 participants Est. completion 2014-12 Stand-aloneOther conditions: Postoperative Pain, Postoperative Laminectomy PainView official trial listing → -
Completed NCT NCT02262754
PF-06372865 In Subjects With Chronic Low Back Pain
Not yet reported Pfizer 302 participants Est. completion 2015-08 46 sitesOther conditions: Chronic Low Back PainView official trial listing → -
Completed NCT NCT02268305
The Use of Methylsulfonylmethane (MSM) in the Treatment of Low Back Pain
Not yet reported Mike O'Callaghan Military Hospital 100 participants Est. completion 2018-06-05 1 siteOther conditions: Low Back PainView official trial listing → -
Withdrawn NCT NCT02281968
NSAIDs for Pain After Ankle Fracture Surgery
Not yet reported Northwell Health Est. completion 2015-12Other conditions: Closed Fracture of AnkleView official trial listing → -
Terminated NCT NCT02293681
An Observational Study of Infliximab in Participants Suffering From Ankylosing Spondylitis With Hip Involvement
Janssen Research & Development, LLC 76 participants Est. completion 2017-05-31 6 sitesOther conditions: Spondylitis, AnkylosingView official trial listing → -
Status unknown NCT NCT02307305
Does Duloxetine Reduce Chronic Pain After Total Knee Arthroplasty?
Not yet reported Hanyang University Seoul Hospital 168 participants Est. completion 2016-12 1 siteOther conditions: Neuropathic PainView official trial listing → -
Withdrawn NCT NCT02322996
Phenotyping Acute Pain for Discovery Research and Directed Therapeutics
East Carolina University Est. completion 2018-02-21 1 siteOther conditions: Post op PainView official trial listing → -
Completed NCT NCT02351024
Phase I Study PK Study With OXP005 and Naprosyn
Not yet reported Oxford Pharmascience Ltd Est. completion 2015-03 1 siteOther conditions: PharmacokineticsView official trial listing → -
Status unknown NCT NCT02355236
Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis
Not yet reported Severance Hospital 106 participants Est. completion 2015-12 10 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT02388191
Naproxen for Pain Control With Intrauterine Device Insertion
Not yet reported Planned Parenthood League of Massachusetts 119 participants Est. completion 2016-04 1 site Stand-aloneOther conditions: ContraceptionView official trial listing → -
Completed NCT NCT02408978
Pilot Study of OXP005 to Assess Gastroduodenal Irritation
Not yet reported Oxford Pharmascience Ltd Est. completion 2015-06 1 siteOther conditions: Gastroduodenal ErosionsView official trial listing → -
Completed NCT NCT02451748
IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIA
Not yet reported University of Illinois at Chicago 32 participants Est. completion 2017-12 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02463552
Naproxen on Tooth Sensitivity Caused by In-office Bleaching
Not yet reported Universidade Federal de Sergipe 50 participants Est. completion 2016-10 1 siteOther conditions: Toothache, Tooth BleachingView official trial listing → -
Completed NCT NCT02494856
Comparison of the Clinical Efficacy of Naproxen, Associated or Not With Esomeprazol, in Lower Third Molar Removal
Not yet reported Giovana Maria Weckwerth 50 participants Est. completion 2016-03 1 siteOther conditions: Pain, Other Surgical Procedures, Impacted Third Molar ToothView official trial listing → -
Completed NCT NCT02500641
Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout
Not yet reported Menarini International Operations Luxembourg SA 196 participants Est. completion 2017-05-10 26 sites Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT02501564
Evaluation of NaproxenSodium and CodeinePhosphate Combination in Osteoarthritis
Not yet reported Istanbul Medeniyet University 135 participants Est. completion 2015-11 Stand-aloneOsteoarthritisView official trial listing → -
Terminated NCT NCT02502006
Variability in Response to Non-steroidal Anti-inflammatory Drugs
Not yet reported University of Pennsylvania 16 participants Est. completion 2022-09 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02519231
Copper IUD Treatment Observation Study
Not yet reported University of Washington 34 participants Est. completion 2017-11 5 sitesOther conditions: MenorrhagiaView official trial listing → -
Status unknown NCT NCT02522130
Different Analgesics Prior to Intrauterine Device (IUD) Insertion: Is There Any Evidence?
Not yet reported Al Hayat National Hospital 200 participants Est. completion 2016-12 2 sitesOther conditions: IUD Insertion ComplicationView official trial listing → -
Completed NCT NCT02528188
Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee
Not yet reported Pfizer 3021 participants Est. completion 2019-02-27 507 sitesOsteoarthritis Other conditions: Chronic PainView official trial listing → -
Completed NCT NCT02549469
Bioequivalence of Single Dose Extended Release Naproxen Sodium (660 mg) Tablet Versus Naproxen Sodium (220 mg) Tablet Three Times Daily
Not yet reported Bayer 32 participants Est. completion 2007-05 Stand-aloneOther conditions: PainView official trial listing → -
Completed NCT NCT02604550
Anterior Cruciate Ligament Pain Study
Not yet reported Emory University 115 participants Est. completion 2016-04 1 siteOther conditions: Anterior Cruciate Ligament ReconstructionView official trial listing → -
Completed NCT NCT02611466
A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee
Not yet reported Astellas Pharma Europe B.V. 215 participants Est. completion 2017-09-29 34 sitesOsteoarthritis Other conditions: Chronic Lower Back PainView official trial listing → -
Completed NCT NCT02632812
Gastrointestinal Integrity After Naproxen + Rebamipide Versus Naproxen + Placebo
Not yet reported Biolab Sanus Farmaceutica 24 participants Est. completion 2014-11Other conditions: Gastrointestinal LesionsView official trial listing → -
Withdrawn NCT NCT02643719
Migraine Treatment in ED
Not yet reported NYU Langone Health Est. completion 2017-10Other conditions: MigraineView official trial listing → -
Completed NCT NCT02646124
Diazepam Use With Standard Management for Acute Low Back Pain
Not yet reported, Not yet reported Montefiore Medical Center 114 participants Est. completion 2016-05 1 siteOther conditions: Low Back PainView official trial listing → -
Completed NCT NCT02665286
Orphenadrine and Methocarbamol for LBP
Not yet reported Montefiore Medical Center 240 participants Est. completion 2017-05 1 siteOther conditions: Low Back PainView official trial listing → -
Completed NCT NCT02667730
Correlation Between Acute Analgesia and Long-Term Function Following Ankle Injuries
Not yet reported Canadian Department of National Defence 168 participants Est. completion 2021-12 1 siteOther conditions: Ligament InjuryView official trial listing → -
Completed NCT NCT02674386
Long-term Observational Study of Subjects From Tanezumab Studies Who Undergo a Total Knee, Hip or Shoulder Replacement
Not yet reported Pfizer 154 participants Est. completion 2019-07-15 79 sitesOsteoarthritisView official trial listing → -
Terminated NCT NCT02689024
Delirium in Elderly Patients With Trauma of the Hip
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 239 participants Est. completion 2023-07-19 5 sitesOther conditions: Hip Fractures, AnesthesiaView official trial listing → -
Completed NCT NCT02702817
Randomized Trial of Low-dose Naproxen in Cognitively Intact Persons at Risk of Alzheimer's Dementia
Not yet reported Douglas Mental Health University Institute 200 participants Est. completion 2017-07-15 1 siteOther conditions: Alzheimer Disease, Cognitive Decline Due to Alzheimer Disease, Mild Cognitive Impairment Due to Alzheimer DiseaseView official trial listing → -
Completed NCT NCT02707094
A Pilot Study Examining the Efficacy of Biomodulator Treatment for Chronic Low Back Pain
Not yet reported Brooke Army Medical Center 75 participants Est. completion 2016-08-31 1 site Stand-aloneOther conditions: Chronic Low Back PainView official trial listing → -
Completed NCT NCT02712957
A Proof-of-Concept Study Assessing NEO6860 in Osteoarthritis Pain
Not yet reported Neomed Institute 54 participants Est. completion 2016-11-24 3 sitesOsteoarthritis Other conditions: PainView official trial listing → -
Completed NCT NCT02769247
Efficacy of Intrauterine Lidocaine and Naproxen for Pain Control With Intrauterine Device Insertion
Not yet reported Walter Reed National Military Medical Center 160 participants Est. completion 2016-12 1 siteOther conditions: Contraception, PainView official trial listing → -
Completed NCT NCT02786446
Comparison of Different Analgesia Drug Regimens for Pain Control During ESWL for Renal Stones
Not yet reported Shifa International Hospital 135 participants Est. completion 2016-01Other conditions: Renal StoneView official trial listing → -
Terminated NCT NCT02847702
A Study to Evaluate the Analgesic Efficacy and Safety of VM902A in Subjects With Osteoarthritis (OA) of the Knee
Not yet reported Purdue Pharma LP 75 participants Est. completion 2016-11-22 31 sitesOsteoarthritisView official trial listing → -
Withdrawn NCT NCT02945839
Improving Health Outcomes of Migraine Patients Who Present to the Emergency Department
Not yet reported NYU Langone Health Est. completion 2019-12 1 siteOther conditions: MigraineView official trial listing → -
Completed NCT NCT02986334
Placebo In Chronic Back Pain (Phase 2)
Not yet reported Apkar Apkarian 94 participants Est. completion 2018-06 1 siteOther conditions: Chronic Low Back PainView official trial listing → -
Completed NCT NCT03028870
A Study to Evaluate the Analgesic Efficacy and Safety of V120083 in Subjects With Osteoarthritis (OA) of the Knee
Not yet reported Purdue Pharma LP 291 participants Est. completion 2017-11-21 30 sitesOther conditions: Osteo Arthritis KneeView official trial listing → -
Completed NCT NCT03031938
Protocol to Monitor the Neurological Development of Infants With Exposure in Utero From Birth to 15 Months in Tanezumab Clinical Studies
Not yet reported Pfizer 4 participants Est. completion 2020-06-04 6 sitesOsteoarthritis Other conditions: Cancer Pain, Recurrent Low Back PainView official trial listing → -
Completed NCT NCT03084536
PECS Block vs. Multimodal Analgesia for Prevention of Persistent Postoperative Pain in Breast Surgery
Not yet reported Washington University School of Medicine 134 participants Est. completion 2021-02-25 1 siteOther conditions: Breast Cancer, Breast Cancer Female, Cancer of BreastView official trial listing → -
Completed NCT NCT03092193
Pharmacogenetic and Pharmacokinetics of Naproxen and Associated Naproxen-esomeprazole
Not yet reported University of Sao Paulo 8 participants Est. completion 2017-10-01 1 siteOther conditions: Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant, Poor Metabolizer Due to Cytochrome p450 CYP2C19 VariantView official trial listing → -
Completed NCT NCT03161093
A Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Naproxen for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip
Not yet reported Regeneron Pharmaceuticals 3307 participants Est. completion 2021-08-27 139 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT03167541
Naproxen Sodium (2 x 220 mg) Fasted Comparative Bioavailability Study
Not yet reported Reckitt Benckiser Healthcare (UK) Limited 18 participants Est. completion 2016-12-02 Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT03183297
Study to Evaluate the Pharmacokinetics and Pharmacodynamics of JMI-001
Not yet reported Sen-Jam Pharmaceutical 48 participants Est. completion 2017-12Other conditions: VeisalgiaView official trial listing → -
Completed NCT NCT03245008
Efficacy and Safety of MT-5547 in Patients With Osteoarthritis Accompanied by Moderate to Severe Pain
Not yet reported, Not yet reported Tanabe Pharma Corporation 626 participants Est. completion 2021-03-09 27 sitesOsteoarthritisView official trial listing → -
Completed NCT NCT03291418
To Compare the Gastrointestinal Safety of a 14-Day Oral Dosing Regimen of ATB-346 to Sodium Naproxen in Healthy Subjects
Not yet reported, Not yet reported Antibe Therapeutics Inc. 258 participants Est. completion 2018-04-30 1 siteOther conditions: Gastric UlcerView official trial listing → -
Completed NCT NCT03347929
NSAIDs in Sciatica NSAIDS IN SCIATICA
Not yet reported Ostfold Hospital Trust 123 participants Est. completion 2023-06-22 4 sitesOther conditions: SciaticaView official trial listing → -
Completed NCT NCT03351439
Efficacy of Multimodal Analgesia Following Hip Arthroscopy
Not yet reported Western University, Canada 100 participants Est. completion 2021-09-30 1 siteOther conditions: Hip Pain ChronicView official trial listing → -
Completed NCT NCT03396250
A Pharmacokinetic Trial of Naproxen Sodium and Diphenhydramine Hydrochloride Soft Capsules Versus Naproxen Sodium and Diphenhydramine Hydrochloride Tablets in Healthy Adult Subjects
Not yet reported Bayer 36 participants Est. completion 2018-03-29 1 site Stand-aloneOther conditions: PainView official trial listing → -
Completed NCT NCT03401177
Treatment of Early Phase Achilles Tendinopathy - the Effect of NSAIDs
Not yet reported Bispebjerg Hospital 70 participants Est. completion 2020-04-27 1 siteOther conditions: Tendon Injuries, Achilles Tendinopathy, InflammationView official trial listing → -
Completed NCT NCT03404206
A Trial to Compare the Duration of Analgesic Efficacy and Safety of Naproxen Sodium Tablets and Ibuprofen Tablets in Postsurgical Dental Pain
Not yet reported Bayer 387 participants Est. completion 2018-07-10 1 site Stand-aloneOther conditions: Pain, PostoperativeView official trial listing → -
Completed NCT NCT03424135
A Pharmacokinetic Trial of Naproxen Sodium and Diphenhydramine Hydrochloride Soft Capsules Versus Naproxen Sodium and Diphenhydramine Hydrochloride Tablets in Healthy Adult Subjects Under Fed Conditions
Not yet reported Bayer 60 participants Est. completion 2018-04-04 1 site Stand-aloneOther conditions: Clinical PharmacologyView official trial listing → -
Completed NCT NCT03448536
A Study to Assess Menstrual Cramp Pain Associated With Primary Dysmenorrhea
Not yet reported Bayer 201 participants Est. completion 2018-09-05 8 sites Stand-aloneOther conditions: DysmenorrheaView official trial listing → -
Completed NCT NCT03472469
MAST Trial: Multi-modal Analgesic Strategies in Trauma
Not yet reported The University of Texas Health Science Center, Houston 1561 participants Est. completion 2019-07-03 1 siteOther conditions: Nonspecific Pain Post Traumatic InjuryView official trial listing → -
Completed NCT NCT03493945
Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (QuEST1)
Not yet reported, Not yet reported National Cancer Institute (NCI) 59 participants Est. completion 2024-10-08 1 siteOther conditions: Metastatic Castration-resistant Prostate Cancer, Prostate Cancer, Prostate Neoplasm, Advanced Solid Tumor, Solid Tumor, Non-metastatic Castration-resistant Prostate CancerView official trial listing → -
Completed NCT NCT03566979
Efficacy and Safety Study of a Test Naproxen Sodium 220mg Tablet in Postoperative Dental Pain
Not yet reported Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division 501 participants Est. completion 2019-04-15 1 site Stand-aloneOther conditions: Post-operative Dental PainView official trial listing → -
Completed NCT NCT03570554
A Pilot Study Assessing the Treatment Responsiveness of a Novel Osteoarthritis Stiffness Scale
Not yet reported Bayer 41 participants Est. completion 2019-06-14 5 sites Stand-aloneOsteoarthritisView official trial listing → -
Withdrawn NCT NCT03651804
Radiofrequency Ablation: Treatment for Posterior Element Pain From Vertebral Compression Fractures
Not yet reported University of California, Davis Est. completion 2023-12-19 1 siteOther conditions: Vertebral Compression Fracture, Facet Joint PainView official trial listing → -
Completed NCT NCT03654326
A Study to Evaluate the Efficacy and Safety of Gefapixant (MK-7264) in Women With Endometriosis-Related Pain (MK-7264-034)
Not yet reported Merck Sharp & Dohme LLC 187 participants Est. completion 2020-06-30 78 sites Stand-aloneOther conditions: Endometriosis-related PainView official trial listing → -
Completed NCT NCT03658473
Evaluation of Rebamipide and Rabeprazole Effect Associated or Not to Prevent Naproxen-induced Gastric Lesions
Not yet reported Galeno Desenvolvimento de Pesquisas Clínicas 32 participants Est. completion 2015-02-04 1 siteOther conditions: Gastric LesionView official trial listing → -
Completed NCT NCT03697720
Examining the Role of Improved NSAID Management in Treating Dysmenorrhea and Bladder Pain
Not yet reported Endeavor Health 26 participants Est. completion 2023-09-27 1 siteOther conditions: Dysmenorrhea, PainView official trial listing → -
Completed NCT NCT03697889
A Study to Assess Bioquivalence Between a Novel Naproxen Sodium 275 mg Film-coated Tablet and Nalgesin Naproxen Sodium 275 mg Film-coated Tablet in Healthy Adult Volunteers
Not yet reported McNeil AB 28 participants Est. completion 2019-01-21 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT03699293
NSAIDs vs. Coxibs in the Presence of Aspirin
Not yet reported Platelet and Thrombosis Research, LLC 8 participants Est. completion 2023-01-01 1 siteCardiovascular disease Other conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03727412
Post Implantation Syndrome and Administration on NSAIDs in Patients Undergoing EVAR for AAA
Not yet reported University of Thessaly 186 participants Est. completion 2021-10-01 1 siteOther conditions: Aneurysm Abdominal, Endovacular RepairView official trial listing → -
Completed NCT NCT03771612
Inflammation and Daily Life Study
Not yet reported University of California, Los Angeles 144 participants Est. completion 2024-06-21 1 siteOther conditions: InflammationView official trial listing → -
Withdrawn NCT NCT03779659
Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children
Not yet reported Boston University Est. completion 2023-02 1 siteOther conditions: Dental Fear, Anesthesia, Local, Pediatric DentistryView official trial listing → -
Completed NCT NCT03794219
Is Kinesio Taping Effective to the Radial Nerve in Patients With Lateral Epicondylitis?
Not yet reported Ankara Education and Research Hospital 80 participants Est. completion 2019-08-01 1 siteOther conditions: Lateral EpicondylitisView official trial listing → -
Completed NCT NCT03879408
Naproxen Sodium/Acetaminophen Proof of Concept Dosing Study
Not yet reported Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division 290 participants Est. completion 2019-11-13 1 site Stand-aloneOther conditions: PainView official trial listing → -
Status unknown NCT NCT03881319
The Efficacy of Different Doses of Acupuncture in Dysmenorrhea
Not yet reported Taipei City Hospital 105 participants Est. completion 2019-12-31 1 siteOther conditions: Premenstrual Syndrome, DysmenorrheaView official trial listing → -
Completed NCT NCT03911570
Crystalline Glucosamine Sulfate Therapy in Hand Osteoarthritis
University of Siena 108 participants Est. completion 2019-02-01 1 siteOsteoarthritisView official trial listing → -
Terminated NCT NCT03949673
Study to Evaluate Arthroplasty Specimens for Osteoarthritis of the Knee and Hip
Not yet reported Regeneron Pharmaceuticals 23 participants Est. completion 2020-08-25 15 sitesOsteoarthritisView official trial listing → -
Terminated NCT NCT04015596
Trial of Naproxen Sodium for the Treatment of OCD in Children With PANDAS
Not yet reported Massachusetts General Hospital 2 participants Est. completion 2025-04-30 1 site Stand-aloneOther conditions: PANDAS, Anxiety Disorder, Autoimmune Diseases, Obsessive-Compulsive DisorderView official trial listing → -
Terminated NCT NCT04038346
Symptomatic Management of Lyme Arthritis
Not yet reported Desiree Neville, MD 3 participants Est. completion 2025-05-12 1 siteOther conditions: Lyme Arthritis, Lyme Disease, ArthritisView official trial listing → -
Completed NCT NCT04066426
Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial Pain
Not yet reported Yuzuncu Yil University 200 participants Est. completion 2019-07-15 1 site Stand-aloneOther conditions: Temporomandibular DisorderView official trial listing → -
Terminated NCT NCT04115098
Individualizing Anti-Inflammatory Medications for Adults With Axial Spondyloarthritis: A Series of N-of 1 Trials
Not yet reported The University of Texas Health Science Center, Houston 42 participants Est. completion 2023-08-11 1 siteOther conditions: Axial SpondyloarthritisView official trial listing → -
Completed NCT NCT04129086
Ketamine for Acute Pain Management After Trauma
Not yet reported The University of Texas Health Science Center, Houston 305 participants Est. completion 2022-09-30 1 siteOther conditions: Trauma Injury, Pain, Opioid UseView official trial listing → -
Completed NCT NCT04132336
Study to Find Out the Optimal Dose of Caffeine in the Combination Tablet of Naproxen Sodium and Caffeine in Patients Experiencing Moderate to Severe Pain After Having Wisdom Teeth Removed
Not yet reported Bayer 193 participants Est. completion 2020-03-03 1 site Stand-aloneOther conditions: Pain, PostoperativeView official trial listing → -
Completed NCT NCT04139824
The Effect of Naproxen on the Pharmacokinetic Profile of LC350189 in Healthy Adults
Not yet reported LG Chem 24 participants Est. completion 2020-02-25 1 siteOther conditions: Gout, HyperuricemiaView official trial listing → -
Completed NCT NCT04145518
Mechanistic Characterization of Uterine Pain
Not yet reported Endeavor Health 183 participants Est. completion 2025-07-23 1 site Stand-aloneOther conditions: Dysmenorrhea (Disorder), Dysmenorrhea Primary, Dysmenorrhea Secondary, Endometrial Diseases, Leiomyoma, Fibroid UterusView official trial listing → -
Completed NCT NCT04183556
The Effect of Turmeric on New Onset Primary Dysmenorrhea
Not yet reported Batman Training and Research Hospital 90 participants Est. completion 2020-04-23 1 siteOther conditions: Primary DysmenorrheaView official trial listing → -
Completed NCT NCT04221165
Opioid Therapy vs Multimodal Analgesia in Head and Neck Cancer
Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 49 participants Est. completion 2023-09-15 1 siteOther conditions: Head and Neck Cancer, Radiation-Induced MucositisView official trial listing → -
Completed NCT NCT04236908
Accessible Acupuncture for the Warrior With Acute Low Back Pain
Not yet reported David Moss 276 participants Est. completion 2025-12-09 1 siteOther conditions: Acupuncture, Low Back PainView official trial listing → -
Completed NCT NCT04285853
Are Opioids Needed After ACL Reconstruction
Not yet reported Emory University 98 participants Est. completion 2022-09-19 3 sitesOther conditions: Anterior Cruciate Ligament RuptureView official trial listing → -
Status unknown NCT NCT04296422
Different Does of Acupuncture on Premenstrual Syndrome Efficacy Analysis
Not yet reported Taipei City Hospital 105 participants Est. completion 2020-09-18 1 siteOther conditions: Premenstrual SyndromeView official trial listing → -
Completed NCT NCT04307940
Study to Collect Information on How Well the Study Drug Naproxen Sodium Tablets Works Compared to Hydrocodone/Acetaminophen Tablets in Order to Relieve Pain in Participants Experiencing Moderate to Severe Pain After Having Their Wisdom Teeth Removed
Not yet reported Bayer 221 participants Est. completion 2020-10-05 1 site Stand-aloneOther conditions: PainView official trial listing → -
Completed NCT NCT04315194
Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination Therapy vs. Oseltamivir Alone for Hospitalised Paediatric Influenza Patients
Mackay Memorial Hospital 54 participants Est. completion 2019-12-29 1 siteOther conditions: Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination Therapy vs. Oseltamivir Alone for Hospitalised Paediatric Influenza PatientsView official trial listing → -
Terminated NCT NCT04325633
Efficacy of Addition of Naproxen in the Treatment of Critically Ill Patients Hospitalized for COVID-19 Infection
Not yet reported Assistance Publique - Hôpitaux de Paris 30 participants Est. completion 2020-12-15 2 sitesOther conditions: COVID-19View official trial listing → -
Completed NCT NCT04384367
Efficacy and Safety of Rizatriptan-Naproxen (10/550 mg) in the Acute Treatment of Migraine
Not yet reported Eurofarma Laboratorios S.A. 2068 participants Est. completion 2024-11-30 2 sitesOther conditions: MigraineView official trial listing → -
Status unknown NCT NCT04438434
Evaluation of Hydrogen Peroxide and Hyaluronic Acid (BMG0703) in the Healing of Post-extraction Sites
Not yet reported University of Milan 57 participants Est. completion 2020-07 1 siteOther conditions: Impacted Third Molar Tooth, Healing Surgical WoundsView official trial listing → -
Completed NCT NCT04447040
Acetaminophen/Naproxen Sodium Dose Ranging Study
Not yet reported Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division 304 participants Est. completion 2021-05-03 1 site Stand-aloneOther conditions: PainView official trial listing → -
Status unknown NCT NCT04449471
Naproxen Pharmacogenetic Study (Project 1, Aim 2)
Not yet reported University of Washington 30 participants Est. completion 2022-07-31 1 site Stand-aloneOther conditions: PharmacogeneticsView official trial listing → -
Status unknown NCT NCT04463420
Safety and Efficacy of PHR 160 Spray on the Outcomes of Patients With COVID-19
Not yet reported Baqiyatallah Medical Sciences University 224 participants Est. completion 2020-12-15 1 siteOther conditions: COVID-19View official trial listing → -
Status unknown NCT NCT04490434
Drug-drug Interaction Between DWP14012 and Three Different Kinds of NSAIDs
Not yet reported Daewoong Pharmaceutical Co. LTD. 110 participants Est. completion 2020-11-30 1 siteOther conditions: Healthy Male VolunteersView official trial listing → -
Completed NCT NCT04499209
Pharmacokinetics Study of XG005 Capsule
Not yet reported Xgene Pharmaceutical Group 50 participants Est. completion 2018-03-19 1 siteOther conditions: PainView official trial listing → -
Completed NCT NCT04566250
Non-Opioid Prescriptions After Arthroscopic Surgery in Canada (NO PAin)
Not yet reported McMaster University 200 participants Est. completion 2022-04-01 3 sitesOther conditions: Knee Arthroscopy, Shoulder ArthroscopyView official trial listing → -
Completed NCT NCT04572828
Effectiveness of Paracervical Block in Endometrial Sampling Procedures for Pain Control
Not yet reported Ege University 120 participants Est. completion 2020-12-28 1 siteOther conditions: Office-based Endometrial Sampling ProceduresView official trial listing → -
Completed NCT NCT04622839
Post-Operative Pain Control Following Shoulder Surgery
Not yet reported Johns Hopkins University 74 participants Est. completion 2022-07-31 1 siteOther conditions: Shoulder PainView official trial listing → -
Completed NCT NCT04639804
Pharmacokinetic Interaction Between Tegoprazan and NSAIDs After Multiple Oral Dosing in Healthy Male Volunteers
Not yet reported HK inno.N Corporation 60 participants Est. completion 2020-07-29 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT04687852
Comparison of the Efficacy of Pharmacology and Non-pharmacological Treatment in Women With Primary Dysmenorrhea.
Not yet reported Istanbul Medipol University Hospital 85 participants Est. completion 2021-12-10 1 siteOther conditions: Pelvic Floor, Exercise, Telerehabilitation, Acupressure, Dysmenorrhea Primary, Drug EffectView official trial listing → -
Completed NCT NCT04694300
OTC Naproxen and Acetaminophen Anti-Inflammatory Action in Dental Implant Patients
Not yet reported Hersh, Elliot V., DMD, MS, PhD 30 participants Est. completion 2022-08-28 1 site Stand-aloneOther conditions: Osseointegrated Dental Implantation, Pain, AcuteView official trial listing → -
Completed NCT NCT04837014
Eliminating Narcotic Prescriptions from Outpatient Minimally Invasive Gynecologic Surgery
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 110 participants Est. completion 2024-10-21 1 siteOther conditions: Pain, Postoperative, Opioid UseView official trial listing → -
Completed NCT NCT04947566
Comparison of Efficacy of Naproxen Versus Ibuprofen
Not yet reported Fatima Memorial Hospital 116 participants Est. completion 2020-02-25 2 sitesOther conditions: Pain, PostoperativeView official trial listing → -
Status unknown NCT NCT04948164
Study of Sumatriptan Naproxen Sodium Succinate Tablets for the Treatment of Acute Migraine Attacks
Not yet reported Peking University Third Hospital 240 participants Est. completion 2021-12-01 1 site Stand-aloneOther conditions: Migraine in AdultsView official trial listing → -
Terminated NCT NCT04990804
Opioid Free vs. Standard Perioperative Pain Regimen for Anterior Cervical Discectomy and Fusion (ACDF) Surgery
Not yet reported Vanderbilt University Medical Center 8 participants Est. completion 2022-02-01 1 siteOther conditions: Opioid Use, Spinal Diseases, Surgery--Complications, Surgery, Postoperative PainView official trial listing → -
Completed NCT NCT05021718
Strengthening Exercise and Activities of Daily Living Instructions for Patients With Lumbar Disc Herniation
Not yet reported Chittagong Medical College 70 participants Est. completion 2019-09-30 1 siteOther conditions: Lumbar Disc HerniationView official trial listing → -
Completed NCT NCT05026320
A Clinical Trial to Compare Safety and Effectiveness for Relieving Tenderness of 10% Naproxen Gel vs. a 2.32% Diclofenac Diethylamine Gel in the Treatment of Strains and Bruises of the Legs.
Not yet reported Bayer 76 participants Est. completion 2021-12-20 1 siteOther conditions: Soft Tissue InjuryView official trial listing → -
Withdrawn NCT NCT05087914
Novel Non-opioid Post-surgical Pain Treatment in Females
Not yet reported Northwestern University Est. completion 2024-01-30 1 siteOther conditions: Acute Pain, Bunionectomy, Toe FusionView official trial listing → -
Completed NCT NCT05099055
Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study
Not yet reported St. Justine's Hospital 42 participants Est. completion 2023-05-05 1 siteOther conditions: Analgesia, Analgesics, Opioid, Anesthesia, Obstetrical, Anesthesia, Spinal, Analgesics, Non-Narcotic, Dexmedetomidine, Analgesia, ObstetricalView official trial listing → -
Status unknown NCT NCT05154682
Pain Management After Surgery
Not yet reported Rothman Institute Orthopaedics 200 participants Est. completion 2022-11-30 1 siteOther conditions: Pain, PostoperativeView official trial listing → -
Status unknown NCT NCT05161221
Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL Reconstruction
Not yet reported Rothman Institute Orthopaedics 154 participants Est. completion 2022-12-31 1 siteOther conditions: Pain, Postoperative, ACLView official trial listing → -
Completed NCT NCT05181124
Compare Pharmacokinetics and Safety of JP-1366 Between Korean and Caucasian
Not yet reported Onconic Therapeutics Inc. 88 participants Est. completion 2021-03-23 1 siteOther conditions: Anti-Ulcer AgentsView official trial listing → -
Completed NCT NCT05237297
Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Naproxen, Aceclofenac, Celecoxib and Ilaprazole
Not yet reported Il-Yang Pharm. Co., Ltd. 72 participants Est. completion 2022-07-27 1 siteOther conditions: Drug Interaction PotentiationView official trial listing → -
Active, not recruiting NCT NCT05430230
Study of Nonsteroidal Anti-inflammatory Drugs in People With Painful Knee Osteoarthritis
Not yet reported Northwestern University 20 participants Est. completion 2027-09-01 1 siteOsteoarthritisView official trial listing → -
Active, not recruiting NCT NCT05463367
Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure
Not yet reported Northwestern University 60 participants Est. completion 2025-06-01 1 siteOther conditions: Opioid Use, Opioid Dependence, Opioid-use Disorder, Narcotic Use, Back Pain, Back Injuries, Chronic Pain, Chronic Low-back Pain, Pain, Chronic, Pain;Back Low;Chronic, Pain, BackView official trial listing → -
Completed NCT NCT05485805
A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo
Not yet reported Bayer 541 participants Est. completion 2024-01-29 1 site Stand-aloneOther conditions: Postoperative Dental PainView official trial listing → -
Status unknown NCT NCT05504382
Effect of Electroacupuncture on Refractory Pain in Juvenile Rheumatoid Arthritis: Randomized Controlled Trial
Not yet reported Mohamed Abdelmoneim El Meligy 42 participants Est. completion 2023-05-01 1 siteOther conditions: Juvenile Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05541185
Effects of Nigella Sativa Oil on Pain Intensity and Physical Functions in Patients With Knee Osteoarthritis
Not yet reported Sultan ÇEÇEN 75 participants Est. completion 2021-03-31 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT05548660
Pharmacogenetic-guided Choice of Post-surgery Analgesics
Not yet reported University of Pennsylvania 112 participants Est. completion 2025-02-01 1 siteOther conditions: Acute Pain, Post Operative PainView official trial listing → -
Completed NCT NCT05761574
A Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen and Naproxen Sodium in Postoperative Dental Pain
Not yet reported Johnson & Johnson Consumer Inc. (J&JCI) 447 participants Est. completion 2024-05-30 1 site Stand-aloneOther conditions: PainView official trial listing → -
Terminated NCT NCT05820685
Dronabinol On the Pain Experience
Not yet reported The University of Texas Health Science Center, Houston 484 participants Est. completion 2024-04-29 1 siteOther conditions: Trauma InjuryView official trial listing → -
Completed NCT NCT05844995
A Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With Pain
Not yet reported Johnson & Johnson Consumer Inc. (J&JCI) 24 participants Est. completion 2024-02-14 1 site Stand-aloneOther conditions: Orthodontic PainView official trial listing → -
Withdrawn NCT NCT05845008
A Multiple-Dose Safety Study of Fixed Combination of Acetaminophen/Naproxen Sodium in Adolescents With Orthodontic Pain
Not yet reported Johnson & Johnson Consumer Inc. (J&JCI) Est. completion 2024-07-26 1 site Stand-aloneOther conditions: Orthodontic PainView official trial listing → -
Completed NCT NCT05854992
Treatments of Migraine with Triptans in Individuals with Elevated Cardiovascular Risk and in Pregnant Women
Mayo Clinic 68419 participants Est. completion 2024-11-01 3 sitesCardiovascular disease Other conditions: Migraine, PregnancyView official trial listing → -
Completed NCT NCT05868122
A Study to Evaluate a Fixed Combination of Acetaminophen/Naproxen Sodium in Acute Postoperative Pain Following Bunionectomy
Not yet reported Johnson & Johnson Consumer Inc. (J&JCI) 143 participants Est. completion 2024-05-30 4 sites Stand-aloneOther conditions: PainView official trial listing → -
Completed NCT NCT05900336
Non-Steroidal Anti-Inflammatory Drug (NSAID) Response and Central Sensitization of Pain in Women With Dysmenorrhea
Not yet reported Mclean Hospital 70 participants Est. completion 2025-08-01 1 siteOther conditions: Dysmenorrhea, Menstrual Pain, Non-steroidal Anti-inflammatory DrugView official trial listing → -
Completed NCT NCT05982392
Effect of Preoperative Tramadol and Naproxen Sodium on Post Operative Pain
Not yet reported, Not yet reported Dow University of Health Sciences 139 participants Est. completion 2023-08-15 1 siteOther conditions: Symptomatic Irreversible Pulpitis, Post Operative PainView official trial listing → -
Completed NCT NCT05995912
Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain
Not yet reported Laboratorios Liomont 58 participants Est. completion 2022-10-14 1 siteOther conditions: Acute Pain, Postoperative PainView official trial listing → -
Not yet recruiting NCT NCT06274151
Optimal Treatment of Acute Skeletal Muscle Injury
Not yet reported Bispebjerg Hospital 20 participants Est. completion 2029-12-31Other conditions: Muscle Strain, Multiple Sites, InflammationView official trial listing → -
Completed NCT NCT06291337
Ibuprofen Inhibits Human Sweet Taste
Not yet reported Rutgers, The State University of New Jersey 32 participants Est. completion 2023-09-30 1 siteOther conditions: Treatment of Sweet Taste Receptors Without or With an Oral Rinse of Ibuprofen Solution in Healthy Participants, Treatment of Sweet Taste Receptors Without or With an Oral Rinse of Naproxen Solution in Healthy ParticipantsView official trial listing → -
Status unknown NCT NCT06344195
Valacyclovir Monotherapy in Pain Management of Acute Periapical Abscesses After Emergency Chamber Opening
Not yet reported Dow University of Health Sciences 82 participants Est. completion 2024-05 1 site Stand-aloneOther conditions: Acute Apical AbscessView official trial listing → -
Completed NCT NCT06415019
A Study to Learn About Whether BAY H006689 Causes an Allergic Reaction When Applied as a Topical Gel in Healthy Participants
Not yet reported Bayer 236 participants Est. completion 2024-08-01 1 siteOther conditions: Pain, Healthy VolunteersView official trial listing → -
Completed NCT NCT06435442
PK,PD and DDI of Epaminurad and Naproxen in Healthy Volunteers
Not yet reported JW Pharmaceutical 57 participants Est. completion 2025-12-30 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT06453291
Assessment of Different Clinical Techniques to Treat Patients With Chronic Low Back Pain
Not yet reported Iffat Anwar Medical Complex 100 participants Est. completion 2025-05 1 siteOther conditions: Chronic Low Back Pain (CLBP)View official trial listing → -
Status unknown NCT NCT06484192
Pain Control After Lumbar Spine Fusion
Not yet reported Rothman Institute Orthopaedics 428 participants Est. completion 2025-06-30 1 siteOther conditions: Spine Fusion, NSAID (Non-Steroidal Anti-Inflammatory Drug), Postoperative PainView official trial listing → -
Completed NCT NCT06511973
A Study to Learn About Whether BAYH006689 Causes Skin Irritation When Applied as a Topical Gel in Healthy Participants
Not yet reported Bayer 42 participants Est. completion 2024-08-20 1 siteOther conditions: Pain, Healthy VolunteersView official trial listing → -
Completed NCT NCT06603181
Effect of Extracorporeal Shock Wave Therapy (ESWT) and Phonophoresis Treatment in Patients With Lateral Epicondylitis
Not yet reported Kirsehir Ahi Evran Universitesi 60 participants Est. completion 2025-04-30 1 siteOther conditions: Lateral Epicondylitis, Extracorporeal Shock Wave Therapy, PhonophoresisView official trial listing → -
Not yet recruiting NCT NCT06868953
Use of the Combination of Sumatriptan and Naproxen in the Acute Treatment of Migraine: Real World Evidence Study
IRCCS San Raffaele Roma 300 participants Est. completion 2026-12-31Other conditions: MigraineView official trial listing → -
Not yet recruiting NCT NCT06903585
Non Steroidal Anti-inflammatory Drugs in the Prevention of Bone Pain Flares After Palliative Radiotherapy
Not yet reported American University of Beirut Medical Center 385 participants Est. completion 2029-04 1 siteOther conditions: Bone Pain Flare, Bone MetastasisView official trial listing → -
Completed NCT NCT06916234
Evaluation of the Analgesic Efficacy of the Combination of Dexketoprofen + Paracetamol and the Combination of Naproxen Sodium + Codeine in Patients With Acute Dental Pain
Not yet reported ibrahim doğru 100 participants Est. completion 2024-01-20 1 siteOther conditions: Acute Dental PainView official trial listing → -
Not yet recruiting NCT NCT06917118
Multimodal Pain Management After Wide Awake Local Anesthesia No Tourniquet Orthopedic Hand Surgery: A Randomized Control Trial
Not yet reported University of Puerto Rico 100 participants Est. completion 2025-12-01 1 siteOther conditions: Pain ManagementView official trial listing → -
Completed NCT NCT06948513
Effect of Over-the-counter Analgesics on Postoperative Pain
Not yet reported Zitelli & Brodland Skin Cancer Center 200 participants Est. completion 2023-06-30 1 siteOther conditions: Pain ManagementView official trial listing → -
Completed NCT NCT07192770
G-CSF-Related Bone Pain and Supportive Care Strategies in Patients With Solid Tumors
Ankara Etlik City Hospital 190 participants Est. completion 2026-02-19 2 sitesOther conditions: Solid Tumors, Chemotherapy-induced NeutropeniaView official trial listing → -
Completed NCT NCT07204379
Effect of Oral Analgesics on Post-op Pain
Not yet reported Armed Forces Institute of Dentistry, Pakistan 100 participants Est. completion 2023-07-31 1 siteOther conditions: Post Operative PainView official trial listing → -
Not yet recruiting NCT NCT07277712
A Study to Evaluate the Pharmacokinetics and Food-effect of IN-M00002 Tablet in Healthy Adult Volunteers
Not yet reported HK inno.N Corporation 74 participants Est. completion 2026-09-30 1 siteOther conditions: Healthy VolunteerView official trial listing → -
Not yet recruiting NCT NCT07296770
An Artificial Intelligence Driven Approach to Optimize Patient Selection for a Transitional Pain Service
Not yet reported University of California, San Francisco 474 participants Est. completion 2029-12-01 1 siteOther conditions: Postsurgical Pain Management, Postsurgical Pain, Chronic, Opioid Use After SurgeryView official trial listing → -
Not yet recruiting NCT NCT07355166
Suzetrigine Versus Usual-care Opioids for Postop Pain in Sports
Not yet reported University of California, Los Angeles 140 participants Est. completion 2027-03Other conditions: Postoperative Pain ManagementView official trial listing → -
Completed NCT NCT07487909
A Study of SJP-001 in Comparison With Fexofenadine and Naproxen Administered With Alcohol
Not yet reported, Not yet reported Sen-Jam Pharmaceutical 47 participants Est. completion 2025-11-21 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Not yet recruiting NCT NCT07546370
The Effectiveness of Topical Prilocaine-Lidocaine Cream Plus Acetaminophen and Naproxen Compared to Lidocaine Injection Plus Acetaminophen and Naproxen to Manage Pain During IntraUterine Device Insertion
Not yet reported Monakshi Sawhney 66 participants Est. completion 2027-04-14 1 siteOther conditions: Pain During Intrauterine Device InsertionView official trial listing → -
Not yet recruiting NCT NCT07549490
Human Experimental Models of Pain (HEMP)
Not yet reported National Center for Complementary and Integrative Health (NCCIH) 25 participants Est. completion 2030-12-31 1 siteOther conditions: Acute PainView official trial listing → -
Enrolling by invitation NCT NCT07606638
Effectiveness of Opioid vs Pregabalin Plus Naproxen Sodium in Pain Management of Oral Cancer Patients
Not yet reported Mayo Hospital Lahore 98 participants Est. completion 2026-07-30 1 site Stand-aloneOther conditions: Oral Cancer, Oral Cavity Cancer, Oral Squamous Cell Carcinoma (OSCC)View official trial listing → -
Not yet recruiting NCT NCT07665476
Naproxen Versus Placebo as Adjunct Treatment of Cellulitis
Not yet reported Ottawa Hospital Research Institute 884 participants Est. completion 2031-12-01 1 siteOther conditions: Cellulitis, Skin Disease, Infectious, Infection, Skin and Soft Tissue Infections (SSTIs)View official trial listing → -
Active, not recruiting NCT NCT07692516
Clinical and Economic Evaluation of Point-of-care Ultrasound-guided Infiltration for Subacromial and Carpal Tunnel Syndromes in Primary Care: a Cluster-randomized Study Protocol.
Not yet reported Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina 225 participants Est. completion 2028-06-30 1 siteOther conditions: Subacromial Impingement Syndrome, Carpal Tunnel Syndrome (CTS), Pain ManagementView official trial listing → -
Completed NCT NCT07706036
Naproxen and Lidocaine Gel Combination for Rib Fracture
Not yet reported Ankara City Hospital Bilkent 110 participants Est. completion 2024-07-02 1 siteOther conditions: Thorax; Fracture, Rib Fracture, Pain ManagementView official trial listing → -
Enrolling by invitation NCT NCT07743606
NSAIDS Following Elective Lumbar Spine Fusion
Not yet reported Rothman Institute Orthopaedics 428 participants Est. completion 2028-12-31 1 siteOther conditions: NSAID (Non-Steroidal Anti-Inflammatory Drug), Lumbar Spine Fusion, Ketorolac, Postoperative PainView official trial listing → -
Enrolling by invitation NCT NCT07750639
Reducing Opioid Use After Upper Extremity Surgery: Testing Lower Prescriptions and Pill Quantity
Not yet reported AdventHealth 300 participants Est. completion 2027-12-30 1 siteOther conditions: Opioid Abuse (Disorder), Opioid Analgesia, Opioid Analgesic Adverse Reaction, Opioid ConsumptionView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Naproxen Sodium, Naproxen Sodium 220mg, up and up naproxen sodium, Naproxen Sodium PM
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
