Modafinil

• Recruiting NCT NCT05333250

  Modafinil to Improve Fatiguability

  Not yet reported, Not yet reported Ottawa Hospital Research Institute 40 participants Est. completion 2028-03 1 site Stand-alone
  Other conditions: Cancer-related Cognitive Difficulties, Cancer-related Problem/Condition, Fatigue
  View official trial listing →
• Recruiting NCT NCT05536011

  WAKIX® (Pitolisant) Pregnancy Registry

  Harmony Biosciences Management, Inc. 1329 participants Est. completion 2030-06-30 1 site
  Other conditions: Pregnancy Related, Narcolepsy
  View official trial listing →
• Recruiting NCT NCT06041048

  Investigation of Locus Coeruleus Function in Sustained Attention

  Not yet reported University of California, Davis 40 participants Est. completion 2026-12-19 1 site
  Other conditions: Attention - no Condition is Being Assessed - Healthy Adults
  View official trial listing →
• Recruiting NCT NCT06592352

  MODAFIMS: A Trial to Evaluate Predictors of Response to MODAFinil in Patients With Multiple Sclerosis

  Not yet reported Clinical Academic Center (2CA-Braga) 64 participants Est. completion 2026-09 1 site Stand-alone
  Other conditions: Multiple Sclerosis, Cognitive Impairment
  View official trial listing →
• Recruiting NCT NCT07231497

  Cognitive Strategies in Early Psychosis 1

  Not yet reported University of Minnesota 103 participants Est. completion 2030-04-30 1 site Stand-alone
  Other conditions: Cognition, Healthy Participants
  View official trial listing →
• Recruiting NCT NCT07263022

  Cognitive Strategies in Early Psychosis 2

  Not yet reported University of Minnesota 24 participants Est. completion 2030-04-30 1 site Stand-alone
  Other conditions: Psychosis, Schizophrenia Disorder, Schizoaffective Disorder, Major Depressive Disorder With Psychotic Features, Bipolar Disorder With Psychotic Features, Psychosis NOS, Schizophreniform Disorder, Psychotic Disorder, Cognition
  View official trial listing →
• Recruiting NCT NCT07582458

  Modafinil for Debilitating Fatigue in Quiescent Inflammatory Bowel Disease MODIFI-IBD Trial)

  Not yet reported, Not yet reported Radboud University Medical Center 60 participants Est. completion 2027-06 2 sites
  Other conditions: Inflammatory Bowel Disease (Crohn's Disease and Ulcerative Colitis), Chronic Fatigue
  View official trial listing →
• Recruiting NCT NCT07830056

  Modafinil to Optimize the Performance of Cold-Stressed Sleep-Deprived Personnel

  Not yet reported United States Army Research Institute of Environmental Medicine 33 participants Est. completion 2026-12 1 site
  Other conditions: Sleep Deprivation, Cold Exposure
  View official trial listing →
• Status unknown NCT NCT00033046

  Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions With Cocaine - 1

  Not yet reported National Institute on Drug Abuse (NIDA) 12 participants Est. completion 2002-04 1 site
  Other conditions: Cocaine-Related Disorders, Drug Administration Schedule, Infusions, Intravenous
  View official trial listing →
• Completed NCT NCT00042848

  Modafinil in Treating Fatigue in Patients Receiving Chemotherapy for Cancer

  Not yet reported Gary Morrow 837 participants Est. completion 2007-10 35 sites
  Other conditions: Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
  View official trial listing →
• Completed NCT NCT00052286

  Modafinil in Treating Fatigue and Behavioral Change in Patients With Primary Brain Cancer

  Not yet reported Jonsson Comprehensive Cancer Center 29 participants Est. completion 2010-08 1 site Stand-alone
  Other conditions: Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Fatigue
  View official trial listing →
• Completed NCT NCT00057707

  Effects of Modafinil on Brain Function in Patients With Schizophrenia

  Not yet reported National Institute of Mental Health (NIMH) 176 participants Est. completion 2017-06-16 1 site
  Other conditions: Schizophrenia, Schizoaffective Disorder
  View official trial listing →
• Completed NCT NCT00066170

  Trial Comparing Effects of Xyrem Taken Orally and Modafinil With Placebo in Treating Daytime Sleepiness in Narcolepsy

  Not yet reported Jazz Pharmaceuticals 231 participants Est. completion 2004-11 40 sites Stand-alone
  Other conditions: Narcolepsy
  View official trial listing →
• Terminated NCT NCT00067496

  Modafinil to Treat Fatigue in Post-Polio Syndrome

  Not yet reported National Institute of Neurological Disorders and Stroke (NINDS) 30 participants Est. completion 2006-08 1 site
  Other conditions: Postpoliomyelitis Syndrome
  View official trial listing →
• Completed NCT NCT00078312

  Armodafinil (CEP-10953) for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder

  Not yet reported Cephalon 328 participants Est. completion 2006-07 50 sites
  Obstructive sleep apnea Other conditions: Narcolepsy, Sleep Apnea, Obstructive, Shift-Work Sleep Disorder
  View official trial listing →
• Completed NCT NCT00078325

  Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome(OSAHS)

  Not yet reported Cephalon 395 participants Est. completion 2004-11
  Obstructive sleep apnea Other conditions: Hypopnea
  View official trial listing →
• Completed NCT NCT00078377

  Safety and Efficacy Study of Armodafinil (CEP-10953) in the Treatment of Excessive Sleepiness Associated With Narcolepsy

  Not yet reported Cephalon 196 participants Est. completion 2005-01
  Other conditions: Narcolepsy
  View official trial listing →
• Completed NCT NCT00079677

  Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea (OSA/H) Syndrome

  Not yet reported Cephalon 263 participants Est. completion 2004-10
  Obstructive sleep apnea Other conditions: Sleep Hypopnea
  View official trial listing →
• Completed NCT NCT00080288

  Safety/Efficacy Study With Armodafinil (CEP-10953) in Treatment of Excessive Sleepiness Associated With Chronic SWSD

  Not yet reported Cephalon 254 participants Est. completion 2004-12
  Other conditions: Excessive Sleepiness, Shift Work Sleep Disorder
  View official trial listing →
• Completed NCT NCT00086281

  Trial of Effects of Oral Xyrem and Zolpidem on Sleep-Disordered Breathing in Obstructive Sleep Apnea Patients

  Not yet reported Jazz Pharmaceuticals 60 participants Est. completion 2005-11 2 sites Stand-alone
  Obstructive sleep apnea
  View official trial listing →
• Completed NCT NCT00100100

  Modafinil for the Treatment of Cocaine Dependence - 1

  Not yet reported National Institute on Drug Abuse (NIDA) 210 participants Est. completion 2006-12 6 sites
  Other conditions: Cocaine-Related Disorders
  View official trial listing →
• Terminated NCT NCT00102284

  Neuromodulation and Language Acquisition (Project Stage Ia)

  Not yet reported University Hospital Muenster 100 participants Est. completion 2005-04 1 site
  Other conditions: Healthy
  View official trial listing →
• Completed NCT NCT00107796

  Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy

  Not yet reported Cephalon 140 participants Est. completion 2005-09 73 sites
  Other conditions: Narcolepsy
  View official trial listing →
• Completed NCT NCT00107809

  Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea Syndrome

  Not yet reported Cephalon 140 participants Est. completion 2005-09 64 sites
  Other conditions: Sleep Apnea, Obstructive
  View official trial listing →
• Completed NCT NCT00107848

  PROVIGIL® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome

  Not yet reported Cephalon 280 participants Est. completion 2005-09 61 sites
  Other conditions: Narcolepsy, Sleep Apnea, Obstructive
  View official trial listing →
• Status unknown NCT NCT00112515

  Modafinil in Treating Fatigue in Patients With Cancer

  Not yet reported University of Virginia 1 site
  Other conditions: Cognitive/Functional Effects, Depression, Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
  View official trial listing →
• Completed NCT NCT00118378

  Effectiveness of Modafinil for Treating Fatigue in Adults With HIV/AIDS

  Not yet reported New York State Psychiatric Institute 115 participants Est. completion 2010-11 1 site Stand-alone
  Other conditions: HIV Infections, Fatigue
  View official trial listing →
• Status unknown NCT NCT00123370

  Trial of Modafinil for Methamphetamine Dependence

  Not yet reported The University of New South Wales 87 participants Est. completion 2007-09 2 sites
  Other conditions: Amphetamine Dependence
  View official trial listing →
• Status unknown NCT NCT00123383

  Randomised Placebo-Controlled Trial of Modafinil for Cocaine Dependence

  Not yet reported The University of New South Wales 10 participants Est. completion 2007-09 2 sites
  Other conditions: Cocaine Dependence
  View official trial listing →
• Completed NCT NCT00124384

  The Effects of Modafinil on Waking Function and on Sleep in Individuals With Primary Insomnia

  Not yet reported University of Rochester 40 participants Est. completion 2007-08 1 site
  Other conditions: Primary Insomnia
  View official trial listing →
• Completed NCT NCT00129285

  Modafinil Treatment for Cocaine-Dependent Individuals

  Not yet reported University of Pennsylvania 210 participants Est. completion 2008-04 1 site Stand-alone
  Other conditions: Cocaine-Related Disorders
  View official trial listing →
• Completed NCT NCT00142402

  Modafinil in Multiple Sclerosis

  Not yet reported Kessler Foundation 20 participants Est. completion 2006-09 1 site
  Other conditions: Multiple Sclerosis
  View official trial listing →
• Completed NCT NCT00142818

  Modafinil and Naltrexone to Reduce Cocaine and Alcohol Dependence

  Not yet reported Kyle Kampman 164 participants Est. completion 2013-08 1 site Stand-alone
  Other conditions: Alcohol-Related Disorders, Alcoholism, Cocaine-Related Disorders
  View official trial listing →
• Completed NCT NCT00174174

  Provigil (Modafinil) Study by Taiwan Biotech Co.

  Not yet reported National Taiwan University Hospital 30 participants
  Other conditions: Narcolepsy, Cataplexy, Sleep Disorders, Hypersomnolence, Excessive Sleepiness
  View official trial listing →
• Completed NCT NCT00178373

  Modafinil to Reduce Persistent Fatigue in Patients Following Treatment for Cancer

  Not yet reported University of Rochester 96 participants Est. completion 2006-03 1 site Stand-alone
  Other conditions: Cancer, Fatigue, Chemotherapy
  View official trial listing →
• Completed NCT NCT00208715

  Provigil in Conjunction With SSRIs for the Treatment of Mild or Moderate Depression With Attendant Symptoms of Sleepiness and Fatigue.

  Not yet reported Emory University 100 participants Est. completion 2004-10 4 sites
  Other conditions: Major Depression, Mental Health
  View official trial listing →
• Status unknown NCT NCT00210301

  Combination Therapy (Provigil + Avonex) to Treat Cognitive Problems in MS

  Not yet reported Institute for Clinical Research 60 participants 1 site
  Other conditions: Relapsing-Remitting Multiple Sclerosis
  View official trial listing →
• Completed NCT NCT00214968

  Assess the Safety and Effectiveness of PROVIGIL Treatment in Children and Adolescents With Excessive Sleepiness

  Not yet reported Cephalon 92 participants Est. completion 2005-10 Stand-alone
  Other conditions: Narcolepsy
  View official trial listing →
• Completed NCT NCT00214981

  Evaluate the Safety and Efficacy of Modafinil in Children and Adolescents With ADHD

  Not yet reported Cephalon Est. completion 2006-09 57 sites
  Other conditions: Attention Deficit/Hyperactivity Disorder, ADHD
  View official trial listing →
• Completed NCT NCT00215176

  Modafinil for Atypical Depression

  Not yet reported, Not yet reported Duke University 65 participants Est. completion 2005-04
  Other conditions: Atypical Depression
  View official trial listing →
• Completed NCT NCT00218023

  Medications for Stopping Cocaine Dependence and Preventing Relapse

  Not yet reported The University of Texas Health Science Center, Houston 101 participants Est. completion 2012-04 1 site Stand-alone
  Other conditions: Cocaine Abuse, Cocaine-Related Disorders
  View official trial listing →
• Terminated NCT NCT00218036

  Pharmacotherapy Dosing Regimen in Cocaine and Opiate Dependent Individuals - 8

  Not yet reported The University of Texas Health Science Center, Houston 54 participants Est. completion 2010-02 1 site Stand-alone
  Other conditions: Cocaine Abuse, Opiate Dependence
  View official trial listing →
• Completed NCT NCT00218062

  Effectiveness of Modafinil and D-amphetamine in Treating Cocaine Dependent Individuals

  Not yet reported The University of Texas Health Science Center, Houston 73 participants Est. completion 2012-01 1 site Stand-alone
  Other conditions: Cocaine-Related Disorders
  View official trial listing →
• Completed NCT NCT00218387

  Modafinil Combined With Cognitive Behavior Therapy to Treat Cocaine Addiction - 1

  Not yet reported Medical University of South Carolina 123 participants Est. completion 2010-07 1 site Stand-alone
  Other conditions: Cocaine Dependence
  View official trial listing →
• Status unknown NCT NCT00220506

  Fatigue Treatment Using Provigil

  Not yet reported Sheba Medical Center 50 participants Est. completion 2006-12 1 site
  Other conditions: All Multiple Sclerosis Patients
  View official trial listing →
• Completed NCT NCT00223691

  Treatment of Orthostatic Hypotension in Autonomic Failure

  Not yet reported Vanderbilt University 389 participants Est. completion 2017-01 1 site Stand-alone
  Other conditions: Autonomic Failure, Orthostatic Hypotension
  View official trial listing →
• Completed NCT NCT00228540

  Study to Assess Satisfaction With Modafinil Treatment in Children and Adolescents With ADHD

  Not yet reported Cephalon Est. completion 2006-09 39 sites
  Other conditions: ADHD
  View official trial listing →
• Completed NCT NCT00228566

  Study to Assess Patient Reported Outcomes With Armodafinil Treatment for Excessive Sleepiness in Adults With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome

  Not yet reported Cephalon 247 participants Est. completion 2006-07 43 sites
  Obstructive sleep apnea Other conditions: Excessive Daytime Sleepiness, Narcolepsy
  View official trial listing →
• Terminated NCT NCT00233090

  Post-Traumatic Brain Injury (Post-TBI) Fatigue and Its Treatment

  Not yet reported Icahn School of Medicine at Mount Sinai 21 participants Est. completion 2008-12 1 site Stand-alone
  Other conditions: Fatigue
  View official trial listing →
• Completed NCT NCT00236080

  Study of the Efficacy and Multiple-Dose Plasma Concentration-Time Profiles of Armodafinil and PROVIGIL

  Not yet reported Cephalon 136 participants Est. completion 2005-12 20 sites
  Other conditions: Chronic Shift Work Sleep Disorder
  View official trial listing →
• Completed NCT NCT00258479

  Safety of Combining Modafinil and Nicotine Replacement Therapy in Treating Nicotine Dependent Adolescents

  Not yet reported Catherine Martin, MD 24 participants Est. completion 2011-12 1 site Stand-alone
  Other conditions: Tobacco Use Disorder
  View official trial listing →
• Active, not recruiting NCT NCT00262470

  Treatment of Orthostatic Intolerance

  Not yet reported, Not yet reported Satish R. Raj 150 participants Est. completion 2029-12 1 site Stand-alone
  Other conditions: Tachycardia, Chronic Orthostatic Intolerance
  View official trial listing →
• Status unknown NCT NCT00265278

  Assessment of Interactions Between Intravenous Methamphetamine and Modafinil - 1

  Not yet reported National Institute on Drug Abuse (NIDA) 16 participants Est. completion 2006-03 1 site
  Other conditions: Amphetamine-Related Disorders
  View official trial listing →
• Terminated NCT NCT00267332

  Modafinil in Opioid Induced Sedation

  Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 90 participants Est. completion 2006-12 1 site
  Other conditions: Cancer, Pain
  View official trial listing →
• Terminated NCT NCT00297284

  Memory and Attention Problems in Lupus: New Treatment Trial With Modafinil

  Not yet reported Hospital for Special Surgery, New York 20 participants Est. completion 2007-02 1 site
  Other conditions: Systemic Lupus Erythematosus
  View official trial listing →
• Terminated NCT NCT00305292

  Modafinil-Alcohol Interactions in Healthy Volunteers

  Not yet reported University of California, San Francisco 32 participants Est. completion 2006-08 1 site
  Other conditions: Alcohol
  View official trial listing →
• Completed NCT NCT00314639

  Modafinil as an Adjunctive on Cognitive Functioning in Patients With Schizophrenia

  Not yet reported, Not yet reported Laval University 30 participants 1 site
  Other conditions: Schizophrenia and Schizophrenia Spectrum Psychosis
  View official trial listing →
• Completed NCT NCT00315276

  Dose-Finding Study to Evaluate the Efficacy and Safety of Modafinil as Treatment for Adults With ADHD

  Not yet reported Cephalon 370 participants Est. completion 2007-01 18 sites
  Other conditions: Attention Deficit Hyperactivity Disorder, ADHD
  View official trial listing →
• Completed NCT NCT00343811

  Study to Evaluate the Efficacy of Modafinil Treatment in Patients With Attention Deficit Hyperactivity Disorder (ADHD) Who Are Responders to Modafinil Treatment

  Not yet reported Cephalon 120 participants Est. completion 2006-09 23 sites
  Other conditions: Attention Deficit Hyperactivity Disorder
  View official trial listing →
• Completed NCT NCT00344565

  A Placebo-Controlled Double-Blind Combined Treatment of Modafinil and CBT for Cocaine Dependence

  Not yet reported Research Foundation for Mental Hygiene, Inc. 15 participants Est. completion 2007-03
  Other conditions: Cocaine Dependence
  View official trial listing →
• Completed NCT NCT00368290

  Modafinil Treatment for Cocaine Dependence and HIV High-Risk Behavior

  Not yet reported Kyle Kampman 94 participants Est. completion 2013-01 Stand-alone
  Other conditions: Cocaine Dependence
  View official trial listing →
• Completed NCT NCT00373672

  Effects of Armodafinil on Cognition for Patients With Schizophrenia or Schizoaffective Disorder

  Not yet reported Northwestern University 58 participants Est. completion 2010-01 1 site
  Other conditions: Schizophrenia, Schizoaffective Disorder
  View official trial listing →
• Withdrawn NCT NCT00393562

  Comparison of Modafinil and Methylphenidate in Treatment of Excessive Daytime Sleepiness in Patients With Parkinson's Disease

  Not yet reported US Department of Veterans Affairs Est. completion 2007-10 1 site
  Other conditions: Parkinson's Disease
  View official trial listing →
• Suspended NCT NCT00396734

  The Effects of Pharmacotherapy on Brain Mechanisms Underlying Cocaine Dependence.

  Not yet reported Hadassah Medical Organization 40 participants Est. completion 2011-04 1 site
  Other conditions: Opioid-Related Disorders, Cocaine-Related Disorders
  View official trial listing →
• Terminated NCT NCT00418691

  Effects of Methylphenidate Versus Sustained Release Methylphenidate on Cognitive Functioning

  Not yet reported M.D. Anderson Cancer Center 34 participants Est. completion 2009-11 1 site
  Other conditions: Brain Tumor
  View official trial listing →
• Completed NCT NCT00423943

  Modafinil for Treatment of Cognitive Dysfunction in Schizophrenia

  Not yet reported University of California, Los Angeles 33 participants Est. completion 2012-12 1 site Stand-alone
  Other conditions: Schizophrenia, Schizoaffective Disorder
  View official trial listing →
• Completed NCT NCT00424931

  A Safety and Effectiveness Study of a Single Dose of JNJ-17216498 in Patients With Narcolepsy

  Not yet reported Alza Corporation, DE, USA 16 participants Est. completion 2007-12 16 sites
  Other conditions: Narcolepsy
  View official trial listing →
• Status unknown NCT NCT00439049

  Substance Abuse Pre-Treatment Screening Study

  The University of Texas Health Science Center, Houston 7500 participants Est. completion 2026-06 1 site
  Alcohol use disorder Other conditions: Cocaine Abuse, Cocaine Dependence, Opiate Dependence, Substance Abuse
  View official trial listing →
• Completed NCT NCT00469508

  Modafinil vs Placebo for the Treatment of Methamphetamine Dependence

  Not yet reported University of California, Los Angeles 71 participants Est. completion 2009-01 1 site
  Other conditions: Methamphetamine Dependence
  View official trial listing →
• Completed NCT NCT00481195

  Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

  Not yet reported Cephalon 257 participants Est. completion 2008-12 55 sites
  Other conditions: Bipolar I Depression
  View official trial listing →
• Completed NCT NCT00487942

  Efficacy and Safety of Armodafinil as Adjunctive Therapy in Schizophrenic Adults With Cognitive Deficits

  Not yet reported Cephalon 60 participants Est. completion 2007-12 12 sites
  Other conditions: Schizophrenia
  View official trial listing →
• Status unknown NCT NCT00489892

  Efficacy of Pharmacological Treatment of Working Memory Impairment After Traumatic Brain Injury: Evaluation With fMRI

  Not yet reported Kessler Foundation 20 participants Est. completion 2008-12 1 site
  Other conditions: Traumatic Brain Injury, Severe Traumatic Brain Injury
  View official trial listing →
• Completed NCT NCT00518986

  Efficacy and Safety of Armodafinil for Adults With Excessive Sleepiness Obstructive Sleep Apnea/Hypopnea and Depression

  Not yet reported Cephalon 249 participants Est. completion 2009-03 62 sites
  Obstructive sleep apnea Other conditions: Sleep Disorders, Major Depressive Disorder, Dysthymic Disorder
  View official trial listing →
• Completed NCT NCT00520286

  Phase 2, Multi-Center Trial of Modafinil for Methamphetamine Dependence

  Not yet reported National Institute on Drug Abuse (NIDA) 210 participants Est. completion 2010-03 8 sites
  Other conditions: Methamphetamine Dependence
  View official trial listing →
• Completed NCT NCT00538655

  A Pilot Trial of Modafinil for Treatment of Methamphetamine Dependence

  Not yet reported California Pacific Medical Center Research Institute 20 participants Est. completion 2011-06 1 site Stand-alone
  Other conditions: Methamphetamine Addiction
  View official trial listing →
• Completed NCT NCT00546403

  Modafinil Augmentation Therapy for Excessive Daytime Sleepiness and Negative Symptoms in Patients With Schizophrenia

  Not yet reported Veterans Medical Research Foundation 26 participants Est. completion 2008-02 1 site Stand-alone
  Other conditions: Schizophrenia
  View official trial listing →
• Completed NCT NCT00555347

  Use of Armodafinil for Fatigue in Sarcoidosis

  Not yet reported, Not yet reported University of Cincinnati 20 participants Est. completion 2011-08 1 site
  Other conditions: Sarcoidosis, Fatigue, Sleepiness
  View official trial listing →
• Completed NCT NCT00569374

  Safety and Tolerability of Modafinil for Methamphetamine Dependence

  Not yet reported University of Arkansas 8 participants 1 site
  Other conditions: Methamphetamine Dependence
  View official trial listing →
• Completed NCT NCT00573417

  A Placebo-Controlled Trial of Modafinil (Provigil) Added to Clozapine in Patients With Schizophrenia

  Not yet reported North Suffolk Mental Health Association 40 participants Est. completion 2007-11 1 site Stand-alone
  Other conditions: Schizophrenia
  View official trial listing →
• Completed NCT NCT00582491

  Modafinil, Sleep, and Cognition in Cocaine Dependence

  Not yet reported Yale University 44 participants Est. completion 2009-02 1 site Stand-alone
  Other conditions: Cocaine Dependence, Substance-induced Sleep Disorder, Substance-induced Cognitive Disorder
  View official trial listing →
• Terminated NCT NCT00591019

  Use of Modafinil in the Treatment of Tinnitus

  Not yet reported University of Arkansas 7 participants Est. completion 2008-06 1 site
  Other conditions: Tinnitus
  View official trial listing →
• Completed NCT NCT00592943

  PET Study Examining the Dopaminergic Activity of Armodafinil in Adults

  Not yet reported, Not yet reported Massachusetts General Hospital 12 participants Est. completion 2010-05 1 site
  Other conditions: Healthy
  View official trial listing →
• Completed NCT NCT00613015

  Stress and Medication Effects on Cocaine Cue Reactivity

  Not yet reported Medical University of South Carolina 109 participants Est. completion 2012-07 1 site Stand-alone
  Other conditions: Cocaine Related Disorders
  View official trial listing →
• Completed NCT NCT00614926

  Modafinil for Treatment of Fatigue in ALS Patients

  Not yet reported New York State Psychiatric Institute 32 participants Est. completion 2008-07 1 site Stand-alone
  Other conditions: Fatigue
  View official trial listing →
• Terminated NCT NCT00620659

  Treatment of Refractory Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome (OSA/HS) Using Nasal Continuous Positive Airway Pressure (nCPAP) Therapy (0249-015)

  Not yet reported Merck Sharp & Dohme LLC 125 participants Est. completion 2009-02 Stand-alone
  Other conditions: Sleep Apnea, Obstructive, Hypopnea Syndrome, Excessive Daytime Sleepiness
  View official trial listing →
• Terminated NCT NCT00626210

  Modafinil Treatment for Sleep/Wake Disturbances in Older Adults

  Not yet reported VA Palo Alto Health Care System 2 participants Est. completion 2012-10 1 site Stand-alone
  Other conditions: Insomnia, Sleep Initiation and Maintenance Disorders, Alzheimer Disease
  View official trial listing →
• Status unknown NCT NCT00630097

  A Dose Ranging Study of Modafinil for Methamphetamine Dependence

  Not yet reported California Pacific Medical Center Research Institute 90 participants Est. completion 2011-06 1 site
  Other conditions: Substance Dependence, Amphetamine Dependence
  View official trial listing →
• Completed NCT NCT00636896

  Effects of Modafinil on Olanzapine Weight Gain

  Not yet reported Neuropsychiatric Research Institute, Fargo, North Dakota 50 participants Est. completion 2007-08 1 site Stand-alone
  Other conditions: Weight Gain
  View official trial listing →
• Completed NCT NCT00650000

  Fasting Study of Modafinil Tablets 200 mg and Provigil® Tablets 200 mg

  Not yet reported Mylan Pharmaceuticals Inc 32 participants Est. completion 2002-10 1 site Stand-alone
  Other conditions: Healthy
  View official trial listing →
• Completed NCT NCT00650286

  Food Study of Modafinil Tablets 200 mg to Provigil® Tablets 200 mg

  Not yet reported Mylan Pharmaceuticals Inc 20 participants Est. completion 2002-10 1 site Stand-alone
  Other conditions: Healthy
  View official trial listing →
• Withdrawn NCT NCT00670813

  Enhancing the Therapeutic Efficacy of Sleep Deprivation by Modafinil

  Not yet reported Technical University of Munich 30 participants Est. completion 2009-11 1 site Stand-alone
  Other conditions: Depression
  View official trial listing →
• Completed NCT NCT00678691

  An Eight Week, Double-Blind Efficacy Study of Armodafinil Augmentation to Alleviate Fibromyalgia Fatigue

  Not yet reported State University of New York - Upstate Medical University 55 participants Est. completion 2009-12 1 site
  Other conditions: Fibromyalgia, Primary
  View official trial listing →
• Completed NCT NCT00701532

  Brain Imaging Study of the Effects of Modafinil in Cocaine Addiction

  Not yet reported Assistance Publique - Hôpitaux de Paris 29 participants Est. completion 2013-01 2 sites Stand-alone
  Other conditions: Cocaine Addiction, Cocaine Dependence
  View official trial listing →
• Completed NCT NCT00702637

  Study of Modafinil to Treat Fatigue in Persons With Traumatic Brain Injury

  Not yet reported Craig Hospital 60 participants Est. completion 2005-03
  Other conditions: Fatigue
  View official trial listing →
• Completed NCT NCT00711464

  Modafinil Effects on Cognition in Schizophrenia Patients

  Not yet reported University of California, Los Angeles 29 participants Est. completion 2012-07 2 sites Stand-alone
  Other conditions: Schizophrenia
  View official trial listing →
• Completed NCT NCT00711516

  Study to Evaluate Armodafinil Treatment in Improving Prefrontal Cortical Activation and Working Memory Performance

  Not yet reported Cephalon 40 participants Est. completion 2009-10 9 sites
  Other conditions: Excessive Sleepiness
  View official trial listing →
• Completed NCT NCT00737204

  Effectiveness of Armodafinil for Treating Fatigue in Adults With HIV/AIDS

  Not yet reported New York State Psychiatric Institute 70 participants Est. completion 2010-09 1 site
  Other conditions: HIV Infections, Fatigue
  View official trial listing →
• Completed NCT NCT00751023

  Effects of Modafinil in Methamphetamine Dependence

  Not yet reported Medical University of South Carolina 40 participants Est. completion 2010-07 1 site Stand-alone
  Other conditions: Methamphetamine Dependence
  View official trial listing →
• Completed NCT NCT00758498

  Study of the Effect of Armodafinil Treatment in Healthy Subjects With Excessive Sleepiness Associated With Jet Lag Disorder

  Not yet reported Cephalon 427 participants Est. completion 2009-02 4 sites
  Other conditions: Excessive Sleepiness
  View official trial listing →
• Completed NCT NCT00766467

  A Randomized Placebo-Controlled Trial of Armodafinil (Nuvigil) for Fatigue in Patients With Malignant Gliomas

  Not yet reported Eudocia Quant Lee, MD 81 participants Est. completion 2014-07 4 sites
  Other conditions: Malignant Glioma
  View official trial listing →
• Completed NCT NCT00772005

  Study to Evaluate the Efficacy and Safety of Armodafinil as Adjunctive Therapy in Adults With Schizophrenia

  Not yet reported Cephalon 287 participants Est. completion 2010-05 39 sites
  Other conditions: Schizophrenia
  View official trial listing →
• Terminated NCT NCT00825227

  Safety and Efficacy of Armodafinil for Fatigue Associated With Taxanes Alone or in Combination With Other Agents

  Not yet reported Cephalon 10 participants Est. completion 2010-02 29 sites
  Other conditions: Fatigue, Chemotherapy Side Effects
  View official trial listing →
• Completed NCT NCT00829322

  Modafinil for the Treatment of Fatigue in Lung Cancer V9.0

  Not yet reported University of Oxford 208 participants Est. completion 2012-05 24 sites Stand-alone
  Other conditions: Carcinoma, Non-Small-Cell Lung
  View official trial listing →
• Withdrawn NCT NCT00838227

  Modafinil Augmentation in Chronic Schizophrenia and Schizoaffective Disorder

  Not yet reported Manhattan Psychiatric Center Est. completion 2012-06 Stand-alone
  Other conditions: Schizophrenia
  View official trial listing →
• Completed NCT NCT00838981

  Pharmacotherapy & CM for Opioid and Cocaine Dependence

  Not yet reported, Not yet reported Yale University 91 participants Est. completion 2014-03 1 site
  Other conditions: Cocaine Dependence
  View official trial listing →
• Completed NCT NCT00842985

  Dronabinol Interactions With Cognitive Enhancing Drug in Humans

  Not yet reported Yale University 53 participants Est. completion 2009-10 1 site
  Other conditions: Cannabis, Marijuana Abuse
  View official trial listing →
• Terminated NCT NCT00859573

  Modafinil for Methamphetamine Dependence

  Not yet reported University of Arkansas 9 participants Est. completion 2010-01 1 site
  Other conditions: Methamphetamine Dependence
  View official trial listing →
• Terminated NCT NCT00893789

  Study to Evaluate the Efficacy and Safety of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain Injury

  Not yet reported Cephalon, Inc. 117 participants Est. completion 2011-01-31 73 sites
  Other conditions: Traumatic Brain Injury
  View official trial listing →
• Completed NCT NCT00895570

  The Effects of Modafinil to Counteract the Adverse Metabolic Consequences of Sleep Restriction

  Not yet reported Brigham and Women's Hospital 20 participants Est. completion 2007-04 1 site Stand-alone
  Other conditions: Sleep Restriction, Impaired Glucose Metabolism
  View official trial listing →
• Completed NCT NCT00916253

  Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies

  Not yet reported University Hospital, Bordeaux 27 participants Est. completion 2012-08 2 sites Stand-alone
  Other conditions: Narcolepsy, Hypersomnia
  View official trial listing →
• Completed NCT NCT00917748

  Study With Modafinil in Patients Treated With Docetaxel-Based Chemotherapy for Metastatic Breast or Prostate Cancer (MOTIF)

  Not yet reported Sanofi 84 participants Est. completion 2011-03 1 site Stand-alone
  Other conditions: Prostatic Neoplasms, Breast Cancer
  View official trial listing →
• Completed NCT NCT00943176

  Modafinil in the Treatment of Fatigue in Patients With Primary Biliary Cirrhosis (PBC)

  Not yet reported Mayo Clinic 40 participants Est. completion 2011-04 1 site Stand-alone
  Other conditions: Fatigue, Primary Biliary Cirrhosis
  View official trial listing →
• Completed NCT NCT00972985

  Acute Effect of Three Neuroactive Drugs Measured by Magnetoencephalography (MEG), Electroencephalography (EEG) and the Synchronous Neural Interaction Test

  Not yet reported Orasi Medical, Inc. 15 participants Est. completion 2009-12 1 site Stand-alone
  Other conditions: Healthy
  View official trial listing →
• Completed NCT NCT00981084

  Impact of Armodafinil on Neurocognition and Cognitive Fatigue in Multiple Sclerosis (MS)

  Not yet reported, Not yet reported University of Missouri, Kansas City 33 participants Est. completion 2011-04 1 site
  Other conditions: Multiple Sclerosis
  View official trial listing →
• Terminated NCT NCT00983437

  Study to Evaluate the Safety, Tolerability, and Efficacy of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain Injury

  Not yet reported Cephalon, Inc. 49 participants Est. completion 2011-01-31 61 sites
  Other conditions: Traumatic Brain Injury
  View official trial listing →
• Completed NCT NCT01010789

  Armodafinil in Binge Eating Disorder (BED)

  Not yet reported Lindner Center of HOPE 60 participants Est. completion 2015-05 1 site
  Other conditions: Binge Eating Disorder, Overweight, Obese
  View official trial listing →
• Completed NCT NCT01011218

  Management of Insomnia in Breast Cancer Patients

  Not yet reported Stanford University 70 participants Est. completion 2016-07 1 site Stand-alone
  Other conditions: Insomnia, Fatigue
  View official trial listing →
• Completed NCT NCT01019187

  Cognitive Behavioral Therapy With or Without Armodafinil in Treating Cancer Survivors With Insomnia and Fatigue After Chemotherapy

  Not yet reported Abramson Cancer Center at Penn Medicine 226 participants Est. completion 2015-08 1 site
  Other conditions: Unspecified Adult Solid Tumor, Protocol Specific
  View official trial listing →
• Completed NCT NCT01023672

  "Pilot Study of Armodafinil in Patients With Dementia With Lewy Bodies"

  Not yet reported Mayo Clinic 20 participants Est. completion 2012-03 1 site
  Other conditions: Dementia With Lewy Bodies
  View official trial listing →
• Completed NCT NCT01032200

  Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors

  Not yet reported Wake Forest University Health Sciences 54 participants Est. completion 2013-01-08 1 site
  Other conditions: Brain Tumors, Nervous System Tumors, Cognition Disorders, Fatigue
  View official trial listing →
• Withdrawn NCT NCT01044004

  Evaluate the Efficacy of Armodafinil for Patients With B-cell Lymphoma and Severe Fatigue

  Not yet reported Washington University School of Medicine Est. completion 2012-06
  Other conditions: B-cell Lymphoma, Fatigue
  View official trial listing →
• Withdrawn NCT NCT01048983

  Reducing Symptom Burden - Non Small Cell Lung Cancer (NSCLC)

  Not yet reported, Not yet reported M.D. Anderson Cancer Center
  Other conditions: Non Small Cell Lung Cancer
  View official trial listing →
• Completed NCT NCT01067222

  Efficacy and Safety Study of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy

  Not yet reported Bioprojet 110 participants Est. completion 2010-12 1 site
  Other conditions: Narcolepsy, Excessive Daytime Sleepiness, Cataplexy, Sleep Disorders
  View official trial listing →
• Completed NCT NCT01067235

  Efficacy and Safety Study of BF2.649 and BF2.649 Add on Modafinil on Cataplexy in Patients With Narcolespy

  Not yet reported Bioprojet 14 participants Est. completion 2010-07 1 site Stand-alone
  Other conditions: Narcolepsy, Cataplexy, Excessive Daytime Sleepiness
  View official trial listing →
• Completed NCT NCT01072630

  Study to Evaluate the Efficacy and Safety of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

  Not yet reported Cephalon 492 participants Est. completion 2012-11 92 sites
  Other conditions: Depression
  View official trial listing →
• Completed NCT NCT01072929

  A Study to Evaluate the Efficacy and Safety of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

  Not yet reported Cephalon 433 participants Est. completion 2012-03 40 sites
  Other conditions: Depression
  View official trial listing →
• Completed NCT NCT01080807

  Efficacy and Tolerability of Armodafinil in Adults With Excessive Sleepiness Associated With Shift Work Disorder

  Not yet reported Cephalon 385 participants Est. completion 2010-10 63 sites
  Other conditions: Excessive Sleepiness
  View official trial listing →
• Completed NCT NCT01085903

  Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia

  Not yet reported University of Arkansas 28 participants Est. completion 2015-08 2 sites
  Other conditions: Spatial Neglect, Dysphagia
  View official trial listing →
• Completed NCT NCT01091974

  Cognitive Behavioral Therapy +/- Armodafinil for Insomnia and Fatigue Following Chemotherapy

  Not yet reported University of Rochester 138 participants Est. completion 2013-04 2 sites
  Other conditions: Insomnia, Fatigue, Breast Cancer
  View official trial listing →
• Completed NCT NCT01092780

  Pharmacodynamics and Efficacy of MK-7288 in Adults With Sleep Apnea (MK-7288-010)

  Not yet reported Merck Sharp & Dohme LLC 56 participants Est. completion 2011-05-31 Stand-alone
  Other conditions: Apnea, Sleep
  View official trial listing →
• Completed NCT NCT01096680

  Pharmacodynamic Profile of SPD489 in Healthy Adult Males Undergoing a Nocturnal Period of Acute Sleep Loss

  Not yet reported Shire 135 participants Est. completion 2010-07-18 1 site
  Other conditions: Sleep Deprivation
  View official trial listing →
• Terminated NCT NCT01121536

  Extension Study of the Safety and Efficacy of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

  Not yet reported Cephalon 867 participants Est. completion 2013-10-31 158 sites
  Other conditions: Depression
  View official trial listing →
• Completed NCT NCT01137396

  Modafinil, Sleep Architecture and Cocaine Relapse

  Not yet reported Yale University 114 participants Est. completion 2015-02 1 site Stand-alone
  Other conditions: Cocaine Dependence
  View official trial listing →
• Completed NCT NCT01160380

  A Study of the Effectiveness of Armodafinil to Treat Cancer-Related Fatigue in Patients With Multiple Myeloma

  Not yet reported Oncotherapeutics 50 participants Est. completion 2014-05 3 sites
  Other conditions: Fatigue, Multiple Myeloma
  View official trial listing →
• Terminated NCT NCT01169753

  Nuvigil in Treatment of Cancer-Related Fatigue in Chronic Myeloid Leukemia Patients

  Not yet reported M.D. Anderson Cancer Center 1 participants Est. completion 2013-02 1 site
  Other conditions: Chronic Myeloid Leukemia
  View official trial listing →
• Completed NCT NCT01172145

  Treatment of Apathy in Alzheimer's Disease With Modafinil

  Not yet reported Brown University 22 participants Est. completion 2007-09 1 site Stand-alone
  Other conditions: Apathy, Alzheimer's Disease
  View official trial listing →
• Terminated NCT NCT01219673

  Symptom Burden in Head and Neck Cancer

  Not yet reported, Not yet reported M.D. Anderson Cancer Center 1 participants Est. completion 2014-01 1 site
  Other conditions: Head And Neck Cancer
  View official trial listing →
• Withdrawn NCT NCT01256905

  Attention Modulation for Treatment of Parkinson's Disease and Dementia With Lewy Bodies

  Not yet reported NYU Langone Health Est. completion 2011-08-08 1 site
  Other conditions: Parkinsons Disease, Lewy Bodies Disease
  View official trial listing →
• Completed NCT NCT01305408

  Study to Evaluate the Efficacy and Safety of Armodafinil Treatment (150 mg/Day) as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

  Not yet reported Cephalon 399 participants Est. completion 2013-07 130 sites
  Other conditions: Depression
  View official trial listing →
• Completed NCT NCT01317550

  A Study for Reducing Symptom Burden Produced by Chemoradiation Treatment for Non Small Cell Lung Cancer by Minocycline and Armodafinil

  Not yet reported M.D. Anderson Cancer Center 14 participants Est. completion 2016-02 1 site
  Other conditions: Lung Cancer
  View official trial listing →
• Completed NCT NCT01330446

  Single Agent Armodafinil for Patient-Reported Fatigue Following Radiation Therapy for Head and Neck Cancer

  Not yet reported, Not yet reported M.D. Anderson Cancer Center 26 participants Est. completion 2022-12-08 2 sites
  Other conditions: Head And Neck Cancer, Fatigue
  View official trial listing →
• Terminated NCT NCT01348607

  Methylphenidate HCl or Modafinil in Treating Young Patients With Excessive Daytime Sleepiness After Cancer Therapy

  Not yet reported University of South Florida 1 participants Est. completion 2012-12 Stand-alone
  Other conditions: Central Nervous System Tumor, Pediatric, Fatigue, Specific Disorders of Sleep
  View official trial listing →
• Completed NCT NCT01354470

  A Randomized, Placebo-Controlled Trial of Modafinil for Methamphetamine Dependence

  Not yet reported California Pacific Medical Center Research Institute 72 participants 2 sites Stand-alone
  Other conditions: Methamphetamine Dependence
  View official trial listing →
• Completed NCT NCT01365897

  Effectiveness of Modafinil in Improving Cognitive Performance of University Students

  Not yet reported Universidad de Valparaiso 128 participants Est. completion 2011-01 2 sites Stand-alone
  Other conditions: Attention, Memory, Short-Term, Executive Function
  View official trial listing →
• Completed NCT NCT01381718

  Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

  Not yet reported University of South Florida 112 participants Est. completion 2016-08 60 sites Stand-alone
  Other conditions: Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Fatigue, Neurotoxicity, Psychosocial Effects of Cancer and Its Treatment
  View official trial listing →
• Terminated NCT NCT01400958

  Nuvigil or Placebo in Newly Diagnosed Malignant Glioma

  Not yet reported H. Lee Moffitt Cancer Center and Research Institute 6 participants Est. completion 2013-09 1 site
  Other conditions: Malignant Glioma
  View official trial listing →
• Completed NCT NCT01440621

  Modafinil in Cancer Related Fatigue

  Not yet reported Indira Gandhi Medical College, Shimla 217 participants Est. completion 2012-02 1 site
  Other conditions: Cancer Related Fatigue, Quality of Life
  View official trial listing →
• Completed NCT NCT01460628

  Effect of Nuvigil on Fatigue

  Not yet reported Massachusetts General Hospital 25 participants Est. completion 2013-12 1 site
  Other conditions: Menopause
  View official trial listing →
• Completed NCT NCT01461174

  Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Deprivation Challenge in Healthy Volunteers

  Not yet reported Qualissima 36 participants Est. completion 2014-11 2 sites Stand-alone
  Other conditions: Healthy
  View official trial listing →
• Terminated NCT NCT01470651

  Armodafinil for Patients Starting Hepatitis C Virus Treatment

  Not yet reported Research Foundation for Mental Hygiene, Inc. 26 participants Est. completion 2014-06 2 sites
  Other conditions: Hepatitis C
  View official trial listing →
• Completed NCT NCT01601730

  Modafinil - Escitalopram Study for Cocaine Dependence

  Not yet reported Baylor College of Medicine 68 participants Est. completion 2011-07 1 site
  Other conditions: Cocaine Dependence, Cocaine Abuse, Cocaine Addiction, Substance Abuse
  View official trial listing →
• Completed NCT NCT01624480

  Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Armodafinil in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy

  Not yet reported Teva Branded Pharmaceutical Products R&D, Inc. 40 participants Est. completion 2015-12 24 sites
  Other conditions: Narcolepsy
  View official trial listing →
• Completed NCT NCT01638403

  Effects of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy.

  Not yet reported Bioprojet 180 participants Est. completion 2012-07 1 site
  Other conditions: Treatment of Excessive Daytime Sleepiness in Narcolepsy
  View official trial listing →
• Completed NCT NCT01684306

  Pharmacological Cognitive Enhancement

  Not yet reported Università degli Studi 'G. d'Annunzio' Chieti e Pescara 26 participants Est. completion 2012-01 1 site Stand-alone
  Other conditions: Fluid Inteligence, Modafinil, Healthy Young Subjects, Resting State Networks
  View official trial listing →
• Status unknown NCT NCT01726088

  Modafinil in the Treatment of PTSD (Posttraumatic Stress Disorder)

  Not yet reported, Not yet reported Biomedical Research Foundation 40 participants Est. completion 2014-05 1 site
  Other conditions: Posttraumatic Stress Disorder
  View official trial listing →
• Completed NCT NCT01746043

  A Phase II Study of Minocycline and Armodafinil for Reducing the Symptom Burden Produced by Chemoradiation Treatment for Esophageal Cancer

  Not yet reported M.D. Anderson Cancer Center 22 participants Est. completion 2017-01 1 site
  Other conditions: Esophageal Cancer
  View official trial listing →
• Status unknown NCT NCT01766323

  Palliative Morphine With or Without Concurrent Modafinil

  Not yet reported Dr. Rajendra Prasad Government Medical College 200 participants Est. completion 2013-08 1 site
  Other conditions: Cancer, Pain Palliation, Excessive Sleepiness
  View official trial listing →
• Completed NCT NCT01778010

  Modafinil for Smoked Cocaine Self-Administration

  Not yet reported New York State Psychiatric Institute 8 participants Est. completion 2013-06 1 site Stand-alone
  Other conditions: Cocaine Dependence
  View official trial listing →
• Completed NCT NCT01781468

  Armodafinil in Reducing Cancer-Related Fatigue in Patients With High Grade Glioma

  Not yet reported Alliance for Clinical Trials in Oncology 328 participants Est. completion 2019-12-15 365 sites
  Other conditions: Fatigue
  View official trial listing →
• Terminated NCT NCT01792583

  The Nuvigil and Provigil Pregnancy Registry

  Cephalon, Inc. 191 participants Est. completion 2023-11-30 1 site
  Obstructive sleep apnea Other conditions: Narcolepsy, Shift Work Sleep Disorder
  View official trial listing →
• Terminated NCT NCT01800097

  Treatment of Post Stroke Fatigue With a Wakefulness Promoting Agent

  Not yet reported Herlev Hospital 41 participants Est. completion 2015-03 1 site
  Cardiovascular disease
  View official trial listing →
• Completed NCT NCT01834547

  Cognitive Hyper-performance - Effects of Stimulating Substances in Chess-players

  Not yet reported K. Lieb 40 participants Est. completion 2013-04 1 site Stand-alone
  Other conditions: Cognitively Healthy Subjects Influenced by Psychoactive Drugs
  View official trial listing →
• Completed NCT NCT01896128

  Combining Armodafinil With Neuro-rehabilitation to Improve Neurological Recovery and Reduce Disability Post-Stroke

  Not yet reported Burke Rehabilitation Hospital 19 participants Est. completion 2015-07 1 site
  Cardiovascular disease Other conditions: Cerebrovascular Accident, Hemiparesis
  View official trial listing →
• Completed NCT NCT01903824

  Pharmacokinetics and Pharmacodynamics (PK/PD) of CEP-26401 in Healthy Subjects

  Not yet reported Teva Branded Pharmaceutical Products R&D, Inc. 40 participants Est. completion 2013-12 1 site Stand-alone
  Other conditions: Cognitive Impairment
  View official trial listing →
• Terminated NCT NCT01913327

  Antipsychotic Effects on Brain Function in Schizophrenia

  Not yet reported University of California, San Francisco 4 participants Est. completion 2017-01 1 site Stand-alone
  Other conditions: Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder
  View official trial listing →
• Completed NCT NCT01951508

  Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study

  Not yet reported University Hospital, Basel, Switzerland 24 participants Est. completion 2014-12 1 site
  Other conditions: Healthy, Substance-related Disorder, Mood Disorder
  View official trial listing →
• Completed NCT NCT01965925

  Targeting Circadian and Cognitive Dysfunction in Bipolar Disorder With Modafinil

  Not yet reported Icahn School of Medicine at Mount Sinai 18 participants Est. completion 2017-11-09 1 site Stand-alone
  Other conditions: Bipolar Disorder
  View official trial listing →
• Active, not recruiting NCT NCT01988883

  Modafinil and Cognitive Function in POTS

  Not yet reported Vanderbilt University Medical Center 20 participants Est. completion 2026-12 1 site Stand-alone
  Other conditions: Postural Tachycardia Syndrome
  View official trial listing →
• Withdrawn NCT NCT02028260

  Modafinil Versus Placebo for Hypoactive Delirium in the Critically Ill

  Not yet reported Brigham and Women's Hospital Est. completion 2015-10 2 sites
  Other conditions: Delirium, Respiratory Failure
  View official trial listing →
• Completed NCT NCT02051153

  Neurochemical Modulation Cognitive Performance and Subjective Wellbeing In Healthy Controls

  Not yet reported Cambridge University Hospitals NHS Foundation Trust 64 participants Est. completion 2011-09 1 site Stand-alone
  Other conditions: Cognitive Performance, Creativity, Motivation, Reward, Healthy Volunteers, Subjective Pleasure
  View official trial listing →
• Completed NCT NCT02071615

  Effects of Modafinil, Caffeine and Methylphenidate in Healthy Volunteers

  Not yet reported Charite University, Berlin, Germany 48 participants Est. completion 2014-03 1 site Stand-alone
  Other conditions: Healthy
  View official trial listing →
• Completed NCT NCT02151253

  Cross-over Study of Armodafinil Treatment of Daytime Sleepiness Associated With Treated Nocturia

  Not yet reported, Not yet reported Duke University 81 participants Est. completion 2015-09 1 site
  Other conditions: Nocturia, Daytime Sleepiness
  View official trial listing →
• Completed NCT NCT02155257

  Pain Expectations in Subjects With Osteoarthritis

  Not yet reported Wake Forest University Health Sciences 30 participants Est. completion 2017-10 1 site
  Osteoarthritis
  View official trial listing →
• Completed NCT NCT02222441

  Effect Of Modafinil And Pioglitazone On The Pharmacokinetics Of Palbociclib (PD-0332991)

  Not yet reported Pfizer 14 participants Est. completion 2014-12 1 site Stand-alone
  Other conditions: Healthy
  View official trial listing →
• Completed NCT NCT02376257

  Improving Therapeutic Learning in Depression: Proof of Concept

  Not yet reported Boston University Charles River Campus 36 participants Est. completion 2017-05 1 site
  Other conditions: Major Depressive Disorder
  View official trial listing →
• Status unknown NCT NCT02385656

  The Efficacy and Tolerability of Modafinil for Fatigue and Daytime Sleepiness in Cancer Patients: Preliminary Study

  Not yet reported Seoul National University Bundang Hospital 20 participants Est. completion 2016-02 1 site Stand-alone
  Other conditions: Fatigue
  View official trial listing →
• Completed NCT NCT02468856

  Effect of Armodafinil on Simulated Driving

  Not yet reported University of Florida 12 participants Est. completion 2017-11-30 1 site
  Other conditions: Healthy Volunteers
  View official trial listing →
• Completed NCT NCT02478580

  Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese Patients

  Not yet reported University of Texas Southwestern Medical Center 67 participants Est. completion 2016-01 1 site
  Other conditions: Obesity, Premature Recovery From Anesthesia
  View official trial listing →
• Terminated NCT NCT02494102

  Evaluation of Modafinil vs Placebo for Treatment of Anesthesia Delayed Emergence in Obstructive Sleep Apnea

  Not yet reported Milton S. Hershey Medical Center 105 participants Est. completion 2018-04-01 1 site
  Obstructive sleep apnea Other conditions: Delayed Emergence From Anesthesia
  View official trial listing →
• Completed NCT NCT02538744

  Complementary Combination Therapy for Cocaine Dependence

  Not yet reported Baylor College of Medicine 45 participants Est. completion 2018-08-21 1 site
  Other conditions: Cocaine Dependence
  View official trial listing →
• Completed NCT NCT02552303

  The Treatment of Insomnia Comorbid With Sleep Disordered Breathing Using Armodafinil and/or Cognitive Behavioral Therapy for Insomnia

  Not yet reported University of Pennsylvania 39 participants Est. completion 2015-07
  Other conditions: Sleep Apnea, Insomnia
  View official trial listing →
• Completed NCT NCT02603861

  A Study of LY3154207 on Sleep in Healthy Male Participants

  Not yet reported Eli Lilly and Company 16 participants Est. completion 2016-03 1 site
  Other conditions: Healthy
  View official trial listing →
• Status unknown NCT NCT02696512

  A Study of IBRF Disorders of Consciousness Advanced Care/MultiModal Care Protocol in Severe Disorders of Consciousness

  Not yet reported, Not yet reported International Brain Research Foundation 30 participants Est. completion 2017-04 1 site Stand-alone
  Other conditions: Brain Injury
  View official trial listing →
• Completed NCT NCT02821715

  Safety and Efficacy of THN102 on Sleepiness in Narcoleptic Patients

  Not yet reported Theranexus 51 participants Est. completion 2019-02 8 sites Stand-alone
  Other conditions: Narcolepsy
  View official trial listing →
• Completed NCT NCT02855229

  Novel Cross-Species Neurophysiological Assays of Reward and Cognitive Domains

  Mclean Hospital 222 participants Est. completion 2021-08-31 1 site
  Other conditions: Translational Electrophysiology
  View official trial listing →
• Withdrawn NCT NCT02857244

  A Multidisciplinary Approach to Manage Gait Difficulty in Parkinson Patients

  Not yet reported University of Chicago Est. completion 2017-11 1 site
  Other conditions: Parkinson's Disease
  View official trial listing →
• Completed NCT NCT02896712

  Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention

  Not yet reported The University of Texas Health Science Center, Houston 118 participants Est. completion 2021-09-13 1 site Stand-alone
  Other conditions: Cocaine-Related Disorders
  View official trial listing →
• Completed NCT NCT03083132

  Modafinil for Freezing of Gait (FOG) in Parkinson's Disease (PD)

  Not yet reported University of Arkansas 21 participants Est. completion 2019-11-12 1 site
  Other conditions: Parkinson Disease
  View official trial listing →
• Completed NCT NCT03182413

  Impact of THN102 on Attention, Wakefulness and Cognitive Performance During Total Sleep Deprivation

  Not yet reported Theranexus 20 participants Est. completion 2016-03 Stand-alone
  Other conditions: Sleep Deprivation
  View official trial listing →
• Completed NCT NCT03185065

  Treatment of Fatigue With Methylphenidate, Modafinil and Amantadine in Multiple Sclerosis

  Not yet reported Johns Hopkins University 141 participants Est. completion 2019-11-21 2 sites Stand-alone
  Other conditions: Fatigue in Multiple Sclerosis
  View official trial listing →
• Completed NCT NCT03424681

  Modafinil for the Treatment of Alcohol Use Disorders

  Not yet reported The Mind Research Network 12 participants Est. completion 2018-08-31 1 site Stand-alone
  Alcohol use disorder
  View official trial listing →
• Status unknown NCT NCT03426202

  The Effect of Modafinil on Affective and Cognitive Processing

  Not yet reported University of Electronic Science and Technology of China 60 participants Est. completion 2020-07-01 1 site Stand-alone
  Other conditions: Healthy
  View official trial listing →
• Status unknown NCT NCT03469089

  Touchscreen-based Cognitive Tests in Healthy Volunteers

  Not yet reported University of Eastern Finland 16 participants Est. completion 2019-12-31 1 site Stand-alone
  Other conditions: Cognitive Symptom, Schizophrenia
  View official trial listing →
• Completed NCT NCT03522506

  A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of TAK-925 Study in Sleep-Deprived Healthy Adults

  Not yet reported Takeda 20 participants Est. completion 2018-11-07 1 site Stand-alone
  Other conditions: Healthy Volunteers
  View official trial listing →
• Completed NCT NCT03616717

  Modafinil Effects on EEG Biomarkers of Reward and Motivation

  Not yet reported University of California, San Diego 23 participants Est. completion 2021-09-30 1 site
  Other conditions: Healthy Adults
  View official trial listing →
• Terminated NCT NCT03620253

  Modafinil's Effects on Cognition in Remitted MDD

  Not yet reported Unity Health Toronto 9 participants Est. completion 2019-08-06 1 site Stand-alone
  Other conditions: Major Depressive Disorder, Cognitive Impairment
  View official trial listing →
• Completed NCT NCT03621761

  Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis Fatigue

  Not yet reported University of Michigan 343 participants Est. completion 2021-11-30 2 sites
  Other conditions: Multiple Sclerosis
  View official trial listing →
• Completed NCT NCT03624920

  Safety and Efficacy of THN102 in Patients With Parkinson's Disease and Excessive Daytime Sleepiness

  Not yet reported Theranexus 77 participants Est. completion 2020-02-24 34 sites Stand-alone
  Other conditions: Parkinson Disease
  View official trial listing →
• Completed NCT NCT03772314

  Modafinil Versus Amphetamines for the Treatment of Narcolepsy Type 2 and Idiopathic Hypersomnia

  Not yet reported Emory University 44 participants Est. completion 2023-05-04 1 site
  Other conditions: Idiopathic Hypersomnia, Narcolepsy Without Cataplexy
  View official trial listing →
• Completed NCT NCT03864042

  Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

  Not yet reported Pfizer 56 participants Est. completion 2023-05-29 29 sites Stand-alone
  Other conditions: Advanced Solid Tumors, Metastatic Melanoma
  View official trial listing →
• Status unknown NCT NCT03893032

  Enhancing Operational Performance in Healthy Rested Soldiers With Pharmacological Stimulants

  Not yet reported United States Army Aeromedical Research Laboratory 80 participants Est. completion 2019-10 1 site Stand-alone
  Other conditions: Cognition
  View official trial listing →
• Completed NCT NCT03914118

  Modafinil to Prevent Postoperative Cognitive Decline

  Not yet reported The Cooper Health System 137 participants Est. completion 2013-01-31
  Other conditions: Postoperative Cognitive Dysfunction
  View official trial listing →
• Completed NCT NCT03961997

  Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants

  Not yet reported Pfizer 16 participants Est. completion 2019-12-09 1 site
  Other conditions: Adult, Drug Interactions, Healthy Volunteers, Humans
  View official trial listing →
• Withdrawn NCT NCT04317001

  Treatment for Cognitive Impairment in Depression

  Not yet reported Stanford University Est. completion 2024-11-30
  Other conditions: Major Depressive Disorder
  View official trial listing →
• Completed NCT NCT04751227

  Modafinil for Wakefulness in the Critical Care Units

  King Faisal Specialist Hospital & Research Center 8 participants Est. completion 2021-01-30 1 site
  Other conditions: Critical Illness, COVID-19, Cognitive Dysfunction
  View official trial listing →
• Completed NCT NCT05066009

  Sleep/Wake State Assessment with Non-invasive Earbuds

  Not yet reported Emory University 8 participants Est. completion 2023-10-27 1 site Stand-alone
  Other conditions: Hypersomnolence
  View official trial listing →
• Active, not recruiting NCT NCT05351541

  Psilocybin Therapy for Chronic Low Back Pain

  Not yet reported, Not yet reported Joshua Woolley, MD, PhD 30 participants Est. completion 2026-09 1 site Stand-alone
  Other conditions: Chronic Low-back Pain
  View official trial listing →
• Not yet recruiting NCT NCT05675098

  Central Nervous System Stimulants and Physical Function in Children With Cerebral Palsy

  Not yet reported Kuwait University 30 participants Est. completion 2027-02-01 1 site Stand-alone
  Other conditions: Neurodevelopmental Disorders, Cerebral Palsy
  View official trial listing →
• Completed NCT NCT05855187

  Bioequivalence Study of Modafinil From Bravamax 200 mg Scored Tablets (Chemipharm Pharmaceutical Industries, Egypt) Versus Vigil 200 mg Tablets (Teva GmbH, Germany)

  Not yet reported Genuine Research Center, Egypt 30 participants Est. completion 2023-01-10 1 site Stand-alone
  Other conditions: Healthy
  View official trial listing →
• Not yet recruiting NCT NCT06354985

  Modafinil and Exercise for Post Stroke Fatigue

  Not yet reported University Health Network, Toronto 212 participants Est. completion 2027-09
  Cardiovascular disease Other conditions: Fatigue, Modafinil, Exercise
  View official trial listing →
• Completed NCT NCT06404086

  RECOVER-SLEEP: Platform Protocol

  Not yet reported Duke University 830 participants Est. completion 2025-12-31 47 sites
  Other conditions: Long COVID, Long COVID-19, Hypersomnia, Sleep Disturbance
  View official trial listing →
• Completed NCT NCT06404099

  RECOVER-SLEEP: Platform Protocol, Appendix_A (Hypersomnia)

  Not yet reported Duke University 361 participants Est. completion 2026-04-20 1 site
  Other conditions: Long COVID, Long COVID-19, Hypersomnia
  View official trial listing →
• Completed NCT NCT06619665

  A Study of MK-6552 in Sleep Deprived Healthy Participants (MK-6552-003)

  Not yet reported Merck Sharp & Dohme LLC 18 participants Est. completion 2024-07-16 2 sites Stand-alone
  Other conditions: Healthy, Narcolepsy
  View official trial listing →
• Completed NCT NCT06665230

  A Clinical Study of MK-6552 and Modafinil in Healthy Men (MK-6552-005)

  Not yet reported Merck Sharp & Dohme LLC 12 participants Est. completion 2023-11-20 1 site Stand-alone
  Other conditions: Healthy, Narcolepsy
  View official trial listing →
• Completed NCT NCT07128719

  Study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia

  Not yet reported Ain Shams University 20 participants Est. completion 2025-06-01 1 site
  Other conditions: Obese Adolescents, Bariatric Surgery
  View official trial listing →
• Not yet recruiting NCT NCT07295834

  Modafinil For Fatigue in IBD: A Feasibility Randomised Controlled Trial

  Not yet reported Imperial College London 70 participants Est. completion 2028-02-01 4 sites
  Other conditions: Crohn Disease (CD), Ulcerative Colitis (UC), Fatigue
  View official trial listing →
• Enrolling by invitation NCT NCT07568574

  Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes

  Not yet reported Enhanced Emirates Limited 60 participants Est. completion 2033-03-01 1 site Stand-alone
  Other conditions: Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes
  View official trial listing →
• Completed NCT NCT07852130

  Reliability of Standardized IQ Testing Under Modafinil, Racetam-Class Compounds, Sleep Restriction and Daily Activity

  Not yet reported Abdulraheem Mohamed Gouda 70 participants Est. completion 2026-09-12 1 site Stand-alone
  Other conditions: Healthy, Cognition, Sleep Deprivation
  View official trial listing →
• Not yet recruiting NCT NCT07887412

  Efficacy and Safety of Modafinil to Treat Fatigue in People With Mitochondrial Disease.

  Not yet reported Kenneth Myers, MD 15 participants Est. completion 2031-01-31 1 site Stand-alone
  Other conditions: Mitochondrial Disease
  View official trial listing →
• Not yet recruiting NCT NCT07895134

  Psilocybin for Depression in Veterans

  Not yet reported VA Office of Research and Development 150 participants Est. completion 2031-12-31 4 sites Stand-alone
  Other conditions: Major Depression
  View official trial listing →

Not yet reported.

Not yet reported.

• ClinicalTrials.gov — NCT07887412

Also known as: Modafinil, Modafinil (M)

No related coverage yet.