GLP-1 Market
LLY $1137.82 ▲ +0.2% NVO $41.71 ▼ -1.9% PFE $27.46 ▼ -0.3% VKTX $29.52 ▼ -1.4% KLRA $12.70 ▼ -5.6% GPCR $35.50 ▼ -8.9% RHHBY $55.15 ▲ +0.4%
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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Methotrexate Sodium

Company
Amgen
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
47 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

47 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Sep 17, 2026

Find a Clinical Trial Near Me

See recruiting studies for Methotrexate Sodium and check eligibility with the study team.

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Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT01848028

    PsoBest - The German Psoriasis Registry

    Universitätsklinikum Hamburg-Eppendorf 3500 participants Est. completion 2032-12 1 site
    Other conditions: Psoriasis, Psoriatic-arthritis
    View official trial listing →
  • Recruiting NCT NCT02836158

    Therapeutic Effects of R-IDARAM and Intrathecal Immunochemotherapy on Elderly Patients With PCNSL

    Not yet reported, Not yet reported Navy General Hospital, Beijing 100 participants Est. completion 2030-12 1 site Stand-alone
    Other conditions: Primary Central Nervous System Lymphoma
    View official trial listing →
  • Recruiting NCT NCT03703271

    Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia

    Not yet reported Women's Hospital School Of Medicine Zhejiang University 70 participants Est. completion 2026-12-31 1 site
    Other conditions: Gestational Trophoblastic Neoplasia
    View official trial listing →
  • Recruiting NCT NCT03719105

    Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

    Not yet reported New York Medical College 40 participants Est. completion 2028-12-31 6 sites Stand-alone
    Other conditions: NK-Cell Lymphoma, NK-Cell Leukemia, Peripheral T Cell Lymphoma
    View official trial listing →
  • Recruiting NCT NCT03785574

    Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule

    Not yet reported Women's Hospital School Of Medicine Zhejiang University 30 participants Est. completion 2030-09-01 1 site Stand-alone
    Other conditions: Hydatidiform Mole, Gestational Trophoblastic Neoplasia
    View official trial listing →
  • Recruiting NCT NCT03959085

    Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

    Not yet reported Children's Oncology Group 5951 participants Est. completion 2032-03-31 231 sites Stand-alone
    Other conditions: B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma, Central Nervous System Leukemia, Mixed Phenotype Acute Leukemia, Testicular Leukemia
    View official trial listing →
  • Recruiting NCT NCT03970096

    Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)

    Not yet reported Fred Hutchinson Cancer Center 120 participants Est. completion 2029-12-31 3 sites Stand-alone
    Other conditions: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm
    View official trial listing →
  • Recruiting NCT NCT04216524

    Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

    Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2026-12-31 1 site Stand-alone
    Other conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm
    View official trial listing →
  • Recruiting NCT NCT04380740

    Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

    Not yet reported Boston Children's Hospital 160 participants Est. completion 2028-06 15 sites Stand-alone
    Other conditions: Graft Vs Host Disease
    View official trial listing →
  • Recruiting NCT NCT04440267

    Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage

    Not yet reported Institute of Hematology & Blood Diseases Hospital, China 50 participants Est. completion 2027-12-20 1 site Stand-alone
    Other conditions: Acute Leukemia of Ambiguous Lineage
    View official trial listing →
  • Recruiting NCT NCT04656431

    Feasibility of Acquiring Hyperpolarized Imaging in Patients With Primary CNS Lymphoma

    Not yet reported James Rubenstein 26 participants Est. completion 2027-03-31 1 site Stand-alone
    Other conditions: Primary CNS Lymphoma
    View official trial listing →
  • Recruiting NCT NCT04725422

    CHronic Nonbacterial Osteomyelitis International Registry

    Seattle Children's Hospital 2000 participants Est. completion 2050-08 1 site
    Other conditions: Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal Osteomyelitis
    View official trial listing →
  • Recruiting NCT NCT05149768

    Open Label Extension Study of Brentuximab Vedotin in Early dcSSc

    Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 11 participants Est. completion 2026-07-01 1 site Stand-alone
    Other conditions: Diffuse Cutaneous Systemic Sclerosis
    View official trial listing →
  • Recruiting NCT NCT05427136

    Early Pulmonary Dysfunction in Childhood Cancer Patients

    University Children's Hospital Basel 140 participants Est. completion 2051-06 5 sites
    Other conditions: Pulmonary Dysfunction
    View official trial listing →
  • Recruiting NCT NCT05428488

    Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis

    Not yet reported University Hospital, Montpellier 220 participants Est. completion 2027-11 17 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Recruiting NCT NCT05518383

    B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021

    Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 300 participants Est. completion 2027-05-16 1 site Stand-alone
    Other conditions: Non-hodgkin Lymphoma,B Cell, Burkitt Lymphoma, Primary Mediastinal Lymphoma, Primary CNS Lymphoma, Diffuse Large B-cell Lymphoma
    View official trial listing →
  • Recruiting NCT NCT05519579

    Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia

    Not yet reported Northside Hospital, Inc. 20 participants Est. completion 2026-12-01 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Recruiting NCT NCT05540938

    Post-marketing Re-evaluation of WangBi Granules for Rheumatoid Arthritis

    Not yet reported China-Japan Friendship Hospital 340 participants Est. completion 2026-03-31 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Recruiting NCT NCT05725200

    Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer

    Not yet reported Oslo University Hospital 40 participants Est. completion 2040-12-31 1 site Stand-alone
    Other conditions: Metastatic Colorectal Cancer
    View official trial listing →
  • Recruiting NCT NCT05998642

    Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary CNS Lymphoma

    Not yet reported Canadian Cancer Trials Group 30 participants Est. completion 2028-12-31 8 sites Stand-alone
    Other conditions: Non-hodgkin Lymphoma
    View official trial listing →
  • Recruiting NCT NCT06099366

    Treatment of Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia in Children

    Not yet reported Hee Young Ju 116 participants Est. completion 2033-12-31 13 sites Stand-alone
    Other conditions: Lymphoblastic Leukemia in Children
    View official trial listing →
  • Recruiting NCT NCT06199557

    A Study to Investigate Treatment of HU and VPA, or 6-MP and VPA in Unfit AML/HR-MDS Patients

    Not yet reported, Not yet reported Haukeland University Hospital 48 participants Est. completion 2029-09-30 1 site
    Other conditions: Acute Myeloid Leukemia, Adult, Myelodysplastic Syndromes, Adult
    View official trial listing →
  • Recruiting NCT NCT06252870

    Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation

    Not yet reported Nantes University Hospital 82 participants Est. completion 2028-07-18 3 sites Stand-alone
    Other conditions: Graft Versus Host Disease, Hematologic Malignancy
    View official trial listing →
  • Recruiting NCT NCT06262438

    CHIP-AML22/Quizartinib: Quizartinib + Chemotherapy in Newly Diagnosed Pediatric FLT3-ITD+ and NPM1wt AML Patients

    Not yet reported Princess Maxima Center for Pediatric Oncology 60 participants Est. completion 2032-06 1 site Stand-alone
    Other conditions: Acute Myeloid Leukemia in Children
    View official trial listing →
  • Recruiting NCT NCT06265584

    Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

    Not yet reported University of Alabama at Birmingham 56 participants Est. completion 2028-11 1 site Stand-alone
    Other conditions: Acute Leukemia, Myelodysplastic Syndrome, Myeloproliferative Disorders
    View official trial listing →
  • Recruiting NCT NCT06289673

    Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

    Not yet reported St. Jude Children's Research Hospital 850 participants Est. completion 2039-05 5 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Mixed Phenotype Acute Leukemia
    View official trial listing →
  • Recruiting NCT NCT06298071

    A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.

    Not yet reported Shanghai Institute Of Biological Products 36 participants Est. completion 2026-12-30 1 site Stand-alone
    Other conditions: Gout
    View official trial listing →
  • Recruiting NCT NCT06373055

    Prediction of Therapeutic Response to Neoadjuvant Chemotherapy in Muscle Invasive Bladder Cancer Patients Using Spatial Transcriptomics

    Yonsei University 250 participants Est. completion 2033-11 1 site
    Other conditions: Muscle-invasive Bladder Cancer
    View official trial listing →
  • Recruiting NCT NCT06516679

    Efficacy of Risk-Stratified Treatment in Newly Diagnosed Infant Leukemia

    Not yet reported Yonsei University 40 participants Est. completion 2032-12-31 10 sites Stand-alone
    Other conditions: Leukemia, Lymphoid
    View official trial listing →
  • Recruiting NCT NCT06528431

    Design and Evaluation of an Individualized Biodrug Tapering Strategy Based on Biodrug Dosage: the MONITORA Study

    Not yet reported Centre Hospitalier Universitaire de Saint Etienne 180 participants Est. completion 2027-12-19 8 sites Stand-alone
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Recruiting NCT NCT06541574

    Prevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) Trial

    Not yet reported Cincinnati Eye Institute, Southwest Ohio 860 participants Est. completion 2026-06 1 site Stand-alone
    Other conditions: Proliferative Vitreoretinopathy, Rhegmatogenous Retinal Detachment
    View official trial listing →
  • Recruiting NCT NCT06615050

    A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

    Not yet reported Incyte Corporation 572 participants Est. completion 2031-01-17 30 sites Stand-alone
    Other conditions: Graft-versus-host Disease (GVHD)
    View official trial listing →
  • Recruiting NCT NCT06682169

    Evaluation of Rovadicitinib Compared to the Protocol Selected by Researchers in Third Line and Subsequent Studies of Moderate to Severe Chronic Graft-versus-host Disease

    Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 182 participants Est. completion 2030-12 41 sites
    Other conditions: Graft-versus-host Disease
    View official trial listing →
  • Recruiting NCT NCT06764238

    Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol

    Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 1800 participants Est. completion 2031-06 27 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia ALL, Childhood Leukemia, Acute Lymphoblastic, B Cell Acute Lymphoblastic Leukemia (B-ALL)
    View official trial listing →
  • Recruiting NCT NCT06855810

    Newly-diagnosed Pediatric T-cell ALL Protocol

    Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 610 participants Est. completion 2031-06 27 sites
    Other conditions: Acute Lymphoblastic Leukemia, Childhood Leukemia, Acute Lymphoblastic, T Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
    View official trial listing →
  • Recruiting NCT NCT06936215

    Safety and Efficacy of Baricitinib on Skin Tightening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate

    Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 24 participants Est. completion 2025-05 1 site
    Other conditions: Diffuse Cutaneous Systemic Sclerosis
    View official trial listing →
  • Recruiting NCT NCT06949982

    Efficacy And Safety Of Hydroxychloroquine Combined With Methotrexate, Capecitabine And Bevacizumab Vs. Regorafenib In Participants With Refractory Metastatic Colorectal Cancer With Mutations In RAS Genes

    Not yet reported Sergey Orlov, MD 60 participants Est. completion 2027-10 1 site Stand-alone
    Other conditions: Metastatic Colorectal Cancer (mCRC), Colorectal Neoplasms
    View official trial listing →
  • Recruiting NCT NCT07124078

    A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)

    Not yet reported Incyte Corporation 60 participants Est. completion 2029-07-31 41 sites
    Other conditions: Chronic Graft-versus-host-disease
    View official trial listing →
  • Recruiting NCT NCT07138898

    Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty

    Not yet reported NYU Langone Health 80 participants Est. completion 2028-01 1 site Stand-alone
    Other conditions: Rheumatic Disease
    View official trial listing →
  • Recruiting NCT NCT07152041

    Newly-diagnosed Pediatric Ph-positive B-ALL Protocol

    Not yet reported Institute of Hematology & Blood Diseases Hospital, China 150 participants Est. completion 2030-06 24 sites
    Other conditions: Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+), Childhood Leukemia, Acute Lymphoblastic
    View official trial listing →
  • Recruiting NCT NCT07228624

    Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes

    Not yet reported Fred Hutchinson Cancer Center 50 participants Est. completion 2030-09-01 1 site Stand-alone
    Other conditions: Myelodysplastic/Myeloproliferative Neoplasm, Primary Myelofibrosis, Secondary Myelofibrosis
    View official trial listing →
  • Recruiting NCT NCT07261306

    Comparison Between Oral Methotrexate and Tofacitinib in Chronic Plaque Psoriasis

    Not yet reported Lahore General Hospital 75 participants Est. completion 2025-12-25 1 site
    Other conditions: Psoriasis
    View official trial listing →
  • Recruiting NCT NCT07294677

    CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL

    Not yet reported, Not yet reported University of Chicago 104 participants Est. completion 2032-03 1 site Stand-alone
    Other conditions: Leukemia, Lymphoma
    View official trial listing →
  • Recruiting NCT NCT07321912

    Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

    Not yet reported Milton S. Hershey Medical Center 406 participants Est. completion 2036-06-01 2 sites Stand-alone
    Obstructive sleep apnea Other conditions: Ewing Sarcoma
    View official trial listing →
  • Recruiting NCT NCT07503652

    Clinical Observation of Xeligekimab in the Treatment of Moderate to Severe Palmoplantar Pustulosis

    Not yet reported First Hospital of China Medical University 10 participants Est. completion 2027-12 1 site Stand-alone
    Other conditions: Palmoplantar Pustulosis (PPP)
    View official trial listing →
  • Recruiting NCT NCT07627893

    Complementary Herbal Approach to Rheumatoid Management Study (CHARMS)

    Not yet reported, Not yet reported Singapore General Hospital 132 participants Est. completion 2030-06-30 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis (RA)
    View official trial listing →
  • Recruiting NCT NCT07689630

    Anti-CD25 Monoclonal Antibody for Prevention of Acute GVHD After Haploidentical HSCT

    Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 186 participants Est. completion 2028-05 1 site
    Other conditions: Graft Versus Host Disease, Hematologic Neoplasms
    View official trial listing →
  • Status unknown NCT NCT00002498

    Combination Chemotherapy Compared With Mitoxantrone in Treating Older Patients With Advanced Breast Cancer

    Not yet reported Leiden University Medical Center 2 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT00002557

    Combination Chemotherapy in Patients With Advanced or Recurrent Mycosis Fungoides

    Not yet reported National Cancer Institute (NCI) 3 participants 1 site
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00002571

    SWOG-9320 Combination Chemotherapy, Radiation Therapy, and Antiviral Therapy in Treating Patients With AIDS-Related Lymphoma

    Not yet reported SWOG Cancer Research Network 52 participants Est. completion 2011-07 85 sites Stand-alone
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00002579

    Tamoxifen Following Combination Chemotherapy in Treating Women With Operable Invasive Breast Cancer

    Not yet reported Scottish Cancer Therapy Network 2000 participants 10 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00002665

    SWOG-9400 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Previously Untreated Acute Lymphocytic Leukemia

    Not yet reported SWOG Cancer Research Network 50 participants Est. completion 2003-12 83 sites
    Other conditions: Leukemia, Neutropenia, Thrombocytopenia
    View official trial listing →
  • Completed NCT NCT00002704

    Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia

    Not yet reported National Cancer Institute (NCI) 156 participants 70 sites Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00002744

    Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia

    Not yet reported Children's Oncology Group 1970 participants Est. completion 2007-03 34 sites Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00002755

    Standard Chemotherapy Compared With High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer

    Not yet reported Scottish Cancer Therapy Network 600 participants Est. completion 1999-06 21 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00002766

    Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma

    Not yet reported Memorial Sloan Kettering Cancer Center 170 participants Est. completion 2011-09 7 sites Stand-alone
    Other conditions: Leukemia, Lymphoma
    View official trial listing →
  • Completed NCT NCT00002798

    Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

    Not yet reported National Cancer Institute (NCI) 880 participants 1 site Stand-alone
    Other conditions: Childhood Acute Erythroleukemia (M6), Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloblastic Leukemia With Maturation (M2), Childhood Acute Myeloblastic Leukemia Without Maturation (M1), Childhood Acute Myelomonocytic Leukemia (M4), Childhood Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes, Refractory Anemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Excess Blasts in Transformation, Refractory Anemia With Ringed Sideroblasts, Secondary Myelodysplastic Syndromes, Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies
    View official trial listing →
  • Completed NCT NCT00002809

    Bone Marrow Transplant Plus Cyclophosphamide and Total-Body Irradiation in Treating Patients With Hematologic Cancer

    Not yet reported Temple University 10 participants Est. completion 2003-12 1 site
    Other conditions: Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
    View official trial listing →
  • Completed NCT NCT00002812

    Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia

    Not yet reported Children's Oncology Group 2078 participants 35 sites Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00002835

    Combination Chemotherapy in Treating Patients With Lymphoma

    Not yet reported M.D. Anderson Cancer Center 116 participants Est. completion 2004-02-04 1 site Stand-alone
    Other conditions: Lymphoma
    View official trial listing →
  • Terminated NCT NCT00003056

    Prevention of Graft-Versus-Host Disease in Patients With Advanced Leukemia or Lymphoma Who Are Eligible for Peripheral Stem Cell Transplantation

    Not yet reported Baxalta now part of Shire 105 participants Est. completion 2003-06-01 13 sites
    Other conditions: Leukemia, Lymphoma, Graft Versus Host Disease
    View official trial listing →
  • Completed NCT NCT00003215

    Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Aggressive Non-Hodgkin's Lymphoma

    Not yet reported Swiss Cancer Institute 400 participants Est. completion 2004-03 12 sites
    Other conditions: Lymphoma
    View official trial listing →
  • Withdrawn NCT NCT00003273

    Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor

    Not yet reported NYU Langone Health 19 sites
    Other conditions: Brain and Central Nervous System Tumors, Neuroblastoma, Retinoblastoma, Sarcoma
    View official trial listing →
  • Completed NCT NCT00003436

    Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myeloid Leukemia

    Not yet reported Medical Research Council 2000 participants Est. completion 2005-12 1 site
    Other conditions: Leukemia, Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00003549

    S9716: Combination Chemotherapy in Treating Patients With Merkel Cell Cancer

    Not yet reported SWOG Cancer Research Network 80 participants Est. completion 2003-01 84 sites
    Other conditions: Neuroendocrine Carcinoma of the Skin
    View official trial listing →
  • Completed NCT NCT00003593

    Chemotherapy in Treating Children With Down Syndrome and Myeloproliferative Disorder, Acute Myelogenous Leukemia, or Myelodysplastic Syndrome

    Not yet reported Children's Oncology Group 254 participants Est. completion 2012-04 237 sites Stand-alone
    Other conditions: Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
    View official trial listing →
  • Completed NCT NCT00003671

    Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia

    Not yet reported Children's Oncology Group 59 participants Est. completion 2009-02 57 sites Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00003700

    Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia

    Not yet reported Alliance for Clinical Trials in Oncology 163 participants Est. completion 2010-01 50 sites Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00004323

    Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia

    Not yet reported National Center for Research Resources (NCRR) 10 participants 1 site
    Other conditions: Aplastic Anemia
    View official trial listing →
  • Completed NCT NCT00004748

    Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis

    Not yet reported National Center for Research Resources (NCRR) 90 participants
    Other conditions: Liver Cirrhosis, Biliary
    View official trial listing →
  • Completed NCT NCT00005086

    Combination Chemotherapy in Treating Patients With Stage IV Locally Advanced or Metastatic Bladder Cancer

    Not yet reported University of Chicago 6 participants Est. completion 2005-04 4 sites Stand-alone
    Other conditions: Bladder Cancer
    View official trial listing →
  • Completed NCT NCT00005802

    Chemotherapy Followed by Donor White Blood Cells Plus Interleukin-2 in Treating Patients With Acute Myeloid or Lymphocytic Leukemia

    Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2005-03 1 site
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00006033

    Interleukin-2 Gene or Methotrexate in Treating Patients With Recurrent or Refractory Stage III or Stage IV Head and Neck Cancer

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute Est. completion 2004-06 1 site
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Completed NCT NCT00008151

    Gemtuzumab Ozogamicin, Fludarabine, and Total-body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

    Not yet reported Fred Hutchinson Cancer Center Est. completion 2002-07 1 site
    Other conditions: Leukemia, Myelodysplastic Syndromes
    View official trial listing →
  • Status unknown NCT NCT00012311

    Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Chemotherapy Alone in Treating Women With Stage IV Breast Cancer

    Not yet reported Herbert Irving Comprehensive Cancer Center 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT00019864

    Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma

    Not yet reported National Cancer Institute (NCI) 100 participants Est. completion 2011-10 4 sites
    Other conditions: Cardiac Toxicity, Sarcoma
    View official trial listing →
  • Completed NCT NCT00024050

    Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Myelodysplastic Syndrome

    Not yet reported Fred Hutchinson Cancer Center Est. completion 2007-08 1 site
    Other conditions: Leukemia, Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00028509

    Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201

    Children's Oncology Group 66 participants 26 sites
    Other conditions: Long-term Effects Secondary to Cancer Therapy in Children, Neurotoxicity
    View official trial listing →
  • Completed NCT NCT00029523

    DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor

    Not yet reported Pacira Pharmaceuticals, Inc 100 participants Est. completion 2004-11 23 sites
    Other conditions: Meningeal Neoplasms
    View official trial listing →
  • Completed NCT NCT00030264

    Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas

    Not yet reported Children's Hospital of Philadelphia 23 participants Est. completion 2016-03 1 site Stand-alone
    Other conditions: Neurofibromatosis Type 1, Precancerous Condition
    View official trial listing →
  • Completed NCT NCT00035074

    A Pharmacokinetic Study to Determine the Oral Bioavailability of Methotrexate in Patients With Inflammatory Bowel Disease

    Not yet reported National Center for Research Resources (NCRR) 1 site
    Other conditions: Inflammatory Bowel Disease
    View official trial listing →
  • Completed NCT NCT00036387

    A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Rheumatoid Arthritis.

    Not yet reported Centocor, Inc. 347 participants Est. completion 2003-11
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Terminated NCT NCT00042406

    Trial With HuMax-CD4 in Participants With Rheumatoid Arthritis (RA) Failing Treatment With Methotrexate (MTX) and a TNF-alpha Blocker

    Not yet reported, Not yet reported Genmab 83 participants Est. completion 2003-03-31 54 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00045539

    Methotrexate and Thiotepa in Treating Patients With Newly Diagnosed Primary CNS Lymphoma

    Not yet reported New Approaches to Brain Tumor Therapy Consortium Est. completion 2006-01 9 sites
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00054340

    Combination Chemotherapy and Antithymocyte Globulin in Reducing Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplantation For Myelodysplastic Syndrome or Myeloproliferative Disorder

    Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2006-09 1 site
    Other conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
    View official trial listing →
  • Completed NCT NCT00074191

    Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma

    Not yet reported OHSU Knight Cancer Institute 1 participants Est. completion 2000-10 1 site
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00083031

    Metronomic Low-Dose Cyclophosphamide and Methotrexate With or Without Bevacizumab in Treating Women With Metastatic Breast Cancer

    Not yet reported Dana-Farber Cancer Institute 57 participants Est. completion 2009-08 4 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT00083759

    Natalizumab in the Treatment of Rheumatoid Arthritis in Subjects Receiving Methotrexate

    Not yet reported Biogen 299 participants 12 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00095147

    Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis

    Not yet reported Bristol-Myers Squibb 431 participants Est. completion 2009-07 76 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00095342

    Study Evaluating TMI-005 in Active Rheumatoid Arthritis

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 390 participants Est. completion 2005-08 8 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00122382

    Remission and Joint Damage Progression in Early Rheumatoid Arthritis

    Not yet reported Bristol-Myers Squibb 1052 participants Est. completion 2009-02 89 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00124982

    Study of Abatacept (BMS-188667) in Subjects With Active Rheumatoid Arthritis on Background Non-biologic DMARDS (Disease Modifying Antirheumatic Drugs) Who Have an Inadequate Response to Anti-TNF Therapy

    Not yet reported Bristol-Myers Squibb 1286 participants Est. completion 2009-08 148 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00132691

    Multicenter Uveitis Steroid Treatment (MUST) Trial

    Not yet reported JHSPH Center for Clinical Trials 255 participants Est. completion 2010-12 23 sites
    Other conditions: Uveitis
    View official trial listing →
  • Completed NCT NCT00134030

    Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma

    Not yet reported Children's Oncology Group 1334 participants Est. completion 2022-09-30 218 sites Stand-alone
    Obstructive sleep apnea
    View official trial listing →
  • Status unknown NCT NCT00137982

    Evaluation of Therapeutic Strategies for Treatment of Ectopic Pregnancies (EP) and Evaluation of Subsequent Fertility

    Not yet reported Hopital Antoine Beclere 600 participants Est. completion 2008-07 18 sites
    Other conditions: Tubal Pregnancy
    View official trial listing →
  • Completed NCT NCT00141830

    Study Evaluating ERB-041 With Methotrexate in Rheumatoid Arthritis

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 159 participants Est. completion 2006-10-19 35 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00147966

    Assessment of Rituximab's Immunomodulatory Synovial Effects (The ARISE Study)

    Not yet reported University of California, San Diego 24 participants Est. completion 2009-12 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00161655

    Study Evaluating Etanercept and Methotrexate in Plaque Psoriasis

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 60 participants Est. completion 2006-12 8 sites
    Other conditions: Psoriasis, Arthritis, Psoriatic
    View official trial listing →
  • Completed NCT NCT00174707

    Study of Docetaxel in Breast Cancer Patients

    Not yet reported Sanofi 998 participants Est. completion 2007-12 1 site Stand-alone
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Completed NCT NCT00194272

    Two-Dose Methotrexate for Ectopic Pregnancy

    Not yet reported University of Pennsylvania 100 participants Est. completion 2007-06 3 sites
    Other conditions: Ectopic Pregnancy
    View official trial listing →
  • Completed NCT NCT00195702

    Efficacy and Safety of Adalimumab in Patients With Active Rheumatoid Arthritis Treated Concomitantly With Methotrexate.

    Not yet reported Abbott 619 participants Est. completion 2010-08 87 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00198978

    German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

    Not yet reported Goethe University 377 participants Est. completion 2014-06 1 site Stand-alone
    Other conditions: Adult Acute Lymphocytic Leukemia
    View official trial listing →
  • Completed NCT NCT00198991

    German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)

    Not yet reported Goethe University 1883 participants Est. completion 2013-06-30 1 site Stand-alone
    Other conditions: Adult Acute Lymphocytic Leukemia
    View official trial listing →
  • Completed NCT NCT00199069

    German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93)

    Not yet reported Goethe University 720 participants Est. completion 2001-05 1 site
    Other conditions: Adult Acute Lymphocytic Leukemia
    View official trial listing →
  • Completed NCT NCT00206219

    Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX)

    Not yet reported AstraZeneca 477 participants Est. completion 2007-09 109 sites
    Other conditions: Squamous Cell Carcinoma of the Head and Neck
    View official trial listing →
  • Completed NCT NCT00209859

    Methotrexate and Cyclosporine in Treatment of Early Rheumatoid Arthritis

    Not yet reported Hvidovre University Hospital 160 participants Est. completion 2007-11 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00221325

    A Safety Study of Rituximab Plus MTX Injected Into the Cerebrospinal Fluid in the Treatment of Brain Lymphoma

    Not yet reported University of California, San Francisco 14 participants Est. completion 2013-03 4 sites Stand-alone
    Other conditions: Central Nervous System Lymphoma, Intraocular Lymphoma
    View official trial listing →
  • Terminated NCT NCT00233558

    Open-Label Steroid Reduction Study of Adalimumab With Methotrexate in Patients With Active Rheumatoid Arthritis

    Not yet reported Abbott 160 participants 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00245037

    Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

    Not yet reported, Not yet reported OHSU Knight Cancer Institute 147 participants Est. completion 2015-08 1 site Stand-alone
    Other conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous Condition
    View official trial listing →
  • Completed NCT NCT00252668

    Study Evaluating the Combination of Etanercept and Methotrexate in Rheumatoid Arthritis Subjects

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 300 participants Est. completion 2005-09
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT00262925

    Combination Chemotherapy and Alemtuzumab in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

    Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2013-02 58 sites Stand-alone
    Other conditions: Recurrent Adult Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00264537

    A Study of the Safety and Efficacy of Golimumab in Subjects With Rheumatoid Arthritis That Are Methotrexate-naive

    Not yet reported Centocor, Inc. 637 participants Est. completion 2012-06 75 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00264550

    An Efficacy and Safety Study of Golimumab in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy

    Not yet reported Centocor, Inc. 444 participants Est. completion 2012-05 50 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00276601

    Combination Chemotherapy in Treating Patients With Acute Promyelocytic Leukemia

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Est. completion 2013-06 7 sites
    Other conditions: Leukemia
    View official trial listing →
  • Status unknown NCT NCT00281905

    Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors

    Not yet reported Children's Cancer and Leukaemia Group 50 participants 21 sites
    Other conditions: Brain and Central Nervous System Tumors, Neuroblastoma
    View official trial listing →
  • Completed NCT NCT00282308

    A Study to Evaluate the Effects of Rituximab on Immune Responses in Subjects With Active Rheumatoid Arthritis Receiving Background Methotrexate

    Not yet reported Genentech, Inc. 103 participants Est. completion 2012-05-28 34 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT00287924

    High-Dose Methotrexate in Treating Young Patients With Residual Ependymoma

    Not yet reported Children's Cancer and Leukaemia Group 29 participants 21 sites
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Completed NCT NCT00290433

    Efficacy of the HCVIDDOXIL Regimen in Patients With Newly Diagnosed Peripheral T-Cell Lymphoma

    Not yet reported M.D. Anderson Cancer Center 55 participants Est. completion 2015-07 1 site Stand-alone
    Other conditions: Lymphoma
    View official trial listing →
  • Status unknown NCT NCT00295997

    Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, or Aplastic Anemia

    Not yet reported University of California, San Francisco 35 participants 2 sites
    Other conditions: Chronic Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
    View official trial listing →
  • Terminated NCT NCT00296010

    Liposomal Doxorubicin Compared With Observation or Cyclophosphamide and Methotrexate in Treating Older Women Who Have Undergone Surgery for Breast Cancer

    Not yet reported ETOP IBCSG Partners Foundation 77 participants Est. completion 2011-12 33 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Withdrawn NCT NCT00298012

    Methotrexate in the Treatment of Axial Spondyloarthritis

    Not yet reported Rheumatism Foundation Hospital 120 participants 5 sites
    Other conditions: Spondylarthropathies, Spondylitis, Ankylosing
    View official trial listing →
  • Completed NCT NCT00299182

    Study of AMG 531 to Evaluate the Safety & Efficacy in Patients With Non-Hodgkin's Lymphoma

    Not yet reported, Not yet reported M.D. Anderson Cancer Center 50 participants Est. completion 2012-04 1 site Stand-alone
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00303810

    Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma

    Not yet reported Universitätsklinikum Hamburg-Eppendorf 567 participants 1 site
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Completed NCT NCT00307671

    Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years

    Not yet reported Assistance Publique - Hôpitaux de Paris 108 participants Est. completion 2011-07 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Vasculitis, Wegener's Granulomatosis, Microscopic Polyangiitis, Churg-Strauss Syndrome
    View official trial listing →
  • Completed NCT NCT00316771

    A Study of P38 Inhibitor (4) in Patients With Active Rheumatoid Arthritis (RA) on Stable Methotrexate Therapy

    Not yet reported Hoffmann-La Roche 374 participants Est. completion 2008-03 114 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT00317408

    Combination Chemotherapy Followed By Stem Cell Transplant in Treating Young Patients With Progressive or Relapsed Anaplastic Large Cell Lymphoma

    Not yet reported European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma 96 participants 98 sites
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00317785

    Total-Body Irradiation and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer and Other Diseases

    Not yet reported Fred Hutchinson Cancer Center 50 participants 2 sites
    Other conditions: Leukemia, Lymphoma, Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00322101

    Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia

    Not yet reported Fred Hutchinson Cancer Center 25 participants Est. completion 2014-10 8 sites Stand-alone
    Other conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Childhood Acute Myeloid Leukemia in Remission, Childhood Myelodysplastic Syndromes, de Novo Myelodysplastic Syndromes, Myelodysplastic Syndrome With Isolated Del(5q), Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00336024

    Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma

    Not yet reported Children's Oncology Group 91 participants Est. completion 2025-09-30 145 sites Stand-alone
    Other conditions: Anaplastic Medulloblastoma, Medulloblastoma, Supratentorial Embryonal Tumor, Not Otherwise Specified, Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
    View official trial listing →
  • Completed NCT NCT00344253

    Randomized, Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediate Uveitis

    Not yet reported Heidelberg University 19 participants Est. completion 2012-01 1 site
    Other conditions: Uveitis, Intermediate, Macular Edema, Multiple Sclerosis
    View official trial listing →
  • Completed NCT NCT00355199

    Comparison of HD Chemotherapy Followed by Auto-transplant and R-CHOP in High Risk Patients With DLBCL.

    Not yet reported Gruppo Italiano Terapie Innovative nei Linfomi 246 participants Est. completion 2013-03 16 sites Stand-alone
    Other conditions: Diffuse Large B-Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT00365001

    A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis.

    Not yet reported Hoffmann-La Roche 23 participants Est. completion 2008-04 11 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00372619

    Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia

    Not yet reported, Not yet reported Children's Oncology Group 74 participants Est. completion 2012-08 79 sites Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00390793

    Combination Chemotherapy and Dasatinib in Treating Participants With Philadelphia Positive or BCR-ABL Positive Acute Lymphoblastic Leukemia.

    Not yet reported M.D. Anderson Cancer Center 107 participants Est. completion 2024-02-02 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, BCR-ABL1 Fusion Protein Expression, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Philadelphia Chromosome Positive, Recurrent Acute Lymphoblastic Leukemia, t(9;22)
    View official trial listing →
  • Completed NCT NCT00392990

    Doxorubicin Hydrochloride Liposome and Rituximab With Combination Chemotherapy in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or Burkitt-Like Lymphoma

    Not yet reported Northwestern University 25 participants Est. completion 2013-05-28 8 sites Stand-alone
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00395577

    A Study in Rheumatoid Arthritis With an Investigational Oral p38 MAP Kinase Inhibitor VX-702

    Not yet reported Vertex Pharmaceuticals Incorporated 120 participants Est. completion 2007-07 17 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT00396812

    Rituximab for the Treatment of Early Rheumatoid Arthritis (RA)

    Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 4 participants Est. completion 2009-07 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00408005

    Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma

    Not yet reported National Cancer Institute (NCI) 1895 participants Est. completion 2025-03-31 215 sites Stand-alone
    Other conditions: T Acute Lymphoblastic Leukemia, T Lymphoblastic Lymphoma
    View official trial listing →
  • Completed NCT NCT00416819

    Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Primary CNS Lymphoma

    Not yet reported University of California, San Francisco 10 participants Est. completion 2012-02 Stand-alone
    Other conditions: Brain and Central Nervous System Tumors, Lymphoma
    View official trial listing →
  • Completed NCT NCT00422227

    Study Comparing Etanercept With Usual DMARD Therapy in Subjects With Rheumatoid Arthritis in the Asia Pacific Region

    Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 300 participants Est. completion 2009-03 27 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00422383

    A Study of Retreatment With MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (RA)

    Not yet reported Hoffmann-La Roche 378 participants Est. completion 2013-03 91 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT00424294

    A Study Of CP-195543 And Celecoxib Dual Therapy In Subjects With Rheumatoid Arthritis

    Not yet reported Pfizer 70 participants Est. completion 2008-02 39 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Terminated NCT NCT00424645

    Voraxaze for Delayed Methotrexate Clearance

    Not yet reported, Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2008-01 1 site
    Other conditions: Hematologic Malignancy, Solid Tumor
    View official trial listing →
  • Terminated NCT NCT00427934

    Maraviroc in Rheumatoid Arthritis

    Not yet reported Pfizer 128 participants Est. completion 2008-10 44 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Completed NCT NCT00440726

    Bortezomib With Chemotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia (ALL)

    Not yet reported, Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 31 participants Est. completion 2011-02-26 24 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00445770

    Study Evaluating the Efficacy and Safety of Etanercept and Methotrexate in Japanese Subjects With Rheumatoid Arthritis

    Not yet reported Pfizer 550 participants Est. completion 2010-07 41 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Completed NCT NCT00448201

    Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease

    Not yet reported UNC Lineberger Comprehensive Cancer Center 71 participants Est. completion 2012-05-23 1 site
    Other conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
    View official trial listing →
  • Terminated NCT NCT00450983

    Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseases

    Not yet reported Fred Hutchinson Cancer Center 1 participants Est. completion 2010-07 2 sites
    Other conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes
    View official trial listing →
  • Completed NCT NCT00458848

    Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia

    Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 470 participants Est. completion 2014-03 66 sites
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00462072

    Centocor Microarray Study of Patients

    Not yet reported University of Rochester 31 participants Est. completion 2010-08 1 site
    Other conditions: Rheumatoid Arthritis, Psoriatic Arthritis, Psoriasis, Crohn's Disease
    View official trial listing →
  • Completed NCT NCT00465933

    Treatment of Acute Promyelocytic Leukemia With All-Trans Retinoic Acid (ATRA) and Idarubicin (AIDA)

    Not yet reported PETHEMA Foundation Est. completion 2007-11 2 sites
    Other conditions: Acute Promyelocytic Leukemia
    View official trial listing →
  • Completed NCT NCT00466258

    LINFOTARGAM: Treatment With Chemotherapy Plus Rituximab and Highly Active Antiretroviral Therapy in Patients With Diffuse Large B Cell Lymphoma and Infection With the Human Immunodeficiency Virus (HIV)

    Not yet reported PETHEMA Foundation 50 participants Est. completion 2009-11 15 sites
    Other conditions: HIV Infections, Diffuse Large B Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT00468546

    A Study to Evaluate the Safety and Efficacy of MabThera (Rituximab) in Combination With Methotrexate (MTX) in Participants With Active Rheumatoid Arthritis Who Failed on Anti-Tumor Necrosis Factor Alpha Therapy

    Not yet reported Hoffmann-La Roche 520 participants Est. completion 2012-07 115 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT00485589

    A Study of Ocrelizumab in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Are Naive to Methotrexate (FILM)

    Not yet reported Genentech, Inc. 613 participants Est. completion 2013-08-29 Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00487825

    Safety and Efficacy of Intravenous ACZ885 and Oral Methotrexate Therapy in Patients With Early Rheumatoid Arthritis

    Not yet reported Novartis 78 participants Est. completion 2008-12 22 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00502853

    A Pilot Study of MabThera (Rituximab) Evaluated by MRI in Patients With Rheumatoid Arthritis.

    Not yet reported Hoffmann-La Roche 10 participants Est. completion 2010-07-23 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00508768

    A Study of Oral SCIO-469 Pharmacokinetics (Study of a Drug in the Body to Watch How the Drug is Absorbed, Distributed, Metabolized and Eliminated Over a Period of Time) in the Body of Female Patients With Active Rheumatoid Arthritis

    Not yet reported Scios, Inc. 16 participants Est. completion 2002-12
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT00517699

    A Study of MabThera (Rituximab) in Primary Central Nervous System Lymphoma.

    Not yet reported Hoffmann-La Roche 5 participants Est. completion 2009-03 2 sites Stand-alone
    Other conditions: Lymphoma
    View official trial listing →
  • No Longer Available NCT NCT00517894

    Dose-Dense Therapy in Aggressive Lymphoma

    Arbeitsgemeinschaft medikamentoese Tumortherapie
    Other conditions: Lymphoma
    View official trial listing →
  • Completed NCT NCT00520130

    Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune System

    Not yet reported, Not yet reported National Cancer Institute (NCI) 92 participants Est. completion 2018-12-31 1 site Stand-alone
    Other conditions: Myelodysplastic Syndrome, Hodgkin's Lymphoma, Non-Hodgkin's Disease, Acute Leukemia, Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT00526175

    LAL-BR/2001: Study Treatment to Low Risk ALL

    Not yet reported PETHEMA Foundation 150 participants Est. completion 2015-12 25 sites
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00537550

    Adult ALL Treatment at Diagnosis

    Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto Est. completion 2006-06 5 sites
    Other conditions: Leukemia, Lymphocytic, Acute
    View official trial listing →
  • Completed NCT NCT00544154

    Efficacy and Safety of CDP870 and Methotrexate Compared to Methotrexate Alone in Subjects With Rheumatoid Arthritis

    Not yet reported UCB Pharma 247 participants Est. completion 2004-01
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Completed NCT NCT00544232

    Preoperative Epirubicin Paclitaxel Aranesp Study (PREPARE)

    Not yet reported GBG Forschungs GmbH 720 participants Est. completion 2006-09 Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00549848

    Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia

    Not yet reported St. Jude Children's Research Hospital 600 participants Est. completion 2022-03-26 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00551460

    S0535, Gemtuzumab and Combination Chemotherapy in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia

    Not yet reported SWOG Cancer Research Network 78 participants Est. completion 2018-02-05 192 sites Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00554164

    Positron Emission Tomography Guided Therapy of Aggressive Non-Hodgkin's Lymphomas

    Not yet reported University Hospital, Essen 1073 participants Est. completion 2017-03 1 site Stand-alone
    Other conditions: Lymphoma, High-grade
    View official trial listing →
  • Completed NCT NCT00554710

    Top Down Versus Step Up Strategies in Crohn's Disease

    Not yet reported Belgian Inflammatory Bowel Disease Research and Development (BIRD) VZW 129 participants Est. completion 2004-01 1 site Stand-alone
    Other conditions: Crohn's Disease
    View official trial listing →
  • Completed NCT NCT00557193

    Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

    Not yet reported Children's Oncology Group 218 participants Est. completion 2024-06-30 170 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Acute Undifferentiated Leukemia, Childhood T Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00558519

    Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

    Not yet reported Alliance for Clinical Trials in Oncology 318 participants Est. completion 2024-06-24 Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00578305

    A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate

    Not yet reported Hoffmann-La Roche 185 participants Est. completion 2013-05 60 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT00578903

    Allogeneic Stem Cell Transplant for Patients With Severe Aplastic Anemia

    Not yet reported Baylor College of Medicine 22 participants Est. completion 2012-07 2 sites Stand-alone
    Other conditions: Aplastic Anemia
    View official trial listing →
  • Completed NCT NCT00579644

    Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone

    Not yet reported University of Nebraska 91 participants Est. completion 2006-05-31 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00586846

    Phase II Study of Chemotherapy and Pamidronate for the Treatment of Newly Diagnosed Osteosarcoma

    Not yet reported Memorial Sloan Kettering Cancer Center 40 participants Est. completion 2009-02 1 site Stand-alone
    Obstructive sleep apnea
    View official trial listing →
  • Completed NCT NCT00587873

    Sequential Administration of Oral 6-Thioguanine (6-TG) After Methotrexate (MTX) in Patients With Relapsed Hodgkin's Disease (Phase II)

    Not yet reported Memorial Sloan Kettering Cancer Center 18 participants Est. completion 2009-06 1 site Stand-alone
    Other conditions: Hodgkin's Disease
    View official trial listing →
  • Completed NCT NCT00588536

    Study of Sequential Administration of Oral 6-Thioguanine After Methotrexate in Patients With LCH

    Not yet reported Memorial Sloan Kettering Cancer Center 5 participants Est. completion 2009-06 1 site Stand-alone
    Other conditions: Langerhans Cell Histiocytosis
    View official trial listing →
  • Completed NCT NCT00599937

    APL93: Timing of CxT and Role of Maintenance

    Not yet reported Groupe d'etude et de travail sur les leucemies aigues promyelocytaires 576 participants Est. completion 1998-12 Stand-alone
    Other conditions: Leukemia, Promyelocytic, Acute
    View official trial listing →
  • Active, not recruiting NCT NCT00602667

    Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma

    Not yet reported St. Jude Children's Research Hospital 293 participants Est. completion 2029-04 6 sites Stand-alone
    Other conditions: Brain and Central Nervous System Tumors
    View official trial listing →
  • Completed NCT NCT00603512

    Comparison Of 4 CP-690,550 Doses Vs. Placebo, Each Combined With Methotrexate, For The Treatment Of Rheumatoid Arthritis in Japan

    Not yet reported Pfizer 140 participants Est. completion 2008-09 18 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Terminated NCT NCT00611455

    Investigating Clinical Efficacy of Ofatumumab in Adult Rheumatoid Arthritis (RA) Patients Who Had an Inadequate Response to MTX Therapy

    Not yet reported GlaxoSmithKline 265 participants Est. completion 2013-07-15 45 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Completed NCT NCT00615901

    Dose Dense Adjuvant CMF (Cyclophosphamide, Methotrexate, Fluorouracil) at 14 and 10-11 Day Intervals for Women With Early Stage Breast Cancer

    Not yet reported Memorial Sloan Kettering Cancer Center 38 participants Est. completion 2010-06 5 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT00616122

    Sunitinib, Cyclophosphamide, and Methotrexate in Treating Patients With Metastatic Breast Cancer

    Not yet reported, Not yet reported University of California, San Francisco 32 participants Est. completion 2012-12-01 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00620685

    A Study To Evaluate The Safety And Pharmacokinetic Profile Of A P38 Inhibitor (PH-797804) In Subjects With Rheumatoid Arthritis Who Are Also Taking Methotrexate

    Not yet reported Pfizer 27 participants Est. completion 2008-10 7 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Withdrawn NCT NCT00621036

    Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma

    Not yet reported University of Texas Southwestern Medical Center Est. completion 2008-12-08 1 site Stand-alone
    Other conditions: Brain and Central Nervous System Tumors, Lymphoma, Lymphoproliferative Disorder, Small Intestine Cancer
    View official trial listing →
  • Completed NCT NCT00639834

    Study of the Safety of MDX-1342 in Combination With Methotrexate in Patients With Rheumatoid Arthritis

    Not yet reported Bristol-Myers Squibb 26 participants Est. completion 2010-06 24 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00642460

    A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA)

    Not yet reported Hoffmann-La Roche 112 participants Est. completion 2014-08 54 sites Stand-alone
    Other conditions: Juvenile Idiopathic Arthritis
    View official trial listing →
  • Completed NCT NCT00653068

    Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System

    Not yet reported Children's Oncology Group 70 participants Est. completion 2024-03-31 94 sites Stand-alone
    Other conditions: Childhood Atypical Teratoid/Rhabdoid Tumor
    View official trial listing →
  • Status unknown NCT NCT00656591

    Community-Based Interventions for Infant Health in Nepal

    Institute of Child Health 192000 participants Est. completion 2008-12 1 site
    Other conditions: Child Mortality
    View official trial listing →
  • Status unknown NCT NCT00666354

    Dose Response and Safety Study of Topical Methotrexate for the Treatment of Fingernail Psoriasis

    Not yet reported MediQuest Therapeutics 83 participants Est. completion 2009-01 7 sites
    Other conditions: Fingernail Psoriasis
    View official trial listing →
  • Completed NCT NCT00669877

    Rituximab and Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) for Burkitt's and Burkitt's -Like Leukemia/Lymphoma

    Not yet reported M.D. Anderson Cancer Center 56 participants Est. completion 2015-10 1 site Stand-alone
    Other conditions: Burkitt's Lymphoma, Burkitt'S-like Lymphoma
    View official trial listing →
  • Completed NCT NCT00673101

    Prospective Evaluation of FibroScan in Patients Treated With Methotrexate

    Association HGE CHU Bordeaux Sud 1871 participants Est. completion 2019-07 1 site
    Other conditions: Liver Fibrosis
    View official trial listing →
  • Terminated NCT NCT00673920

    A Study to Evaluate Ocrelizumab Compared With Placebo in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate Therapy

    Not yet reported Genentech, Inc. 314 participants Est. completion 2009-10-26 Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT00687648

    Cyclophosphamide, Methotrexate, and Prednisolone With or Without Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer

    Not yet reported National Cancer Centre, Singapore 70 participants 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT00697593

    ChangE From Any Systemic psoriasiS therapY to Raptiva

    Not yet reported Merck KGaA, Darmstadt, Germany 70 participants Est. completion 2009-04 1 site
    Other conditions: Chronic Plaque Psoriasis
    View official trial listing →
  • Completed NCT NCT00707083

    Two Combination Chemotherapy Regimens in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia

    Not yet reported Prince of Wales Hospital, Shatin, Hong Kong 2231 participants Est. completion 2020-03-01 2 sites Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT00712114

    Safety, Tolerance, Pharmacokinetics and Activity of HE3286 in Patients With Rheumatoid Arthritis

    Not yet reported, Not yet reported Harbor Therapeutics 14 participants Est. completion 2009-07 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00720798

    An Extension Study of Tocilizumab (Myeloma Receptor Antibody [MRA]) in Patients Completing Treatment in Tocilizumab Core Studies

    Not yet reported Hoffmann-La Roche 2067 participants Est. completion 2013-04 295 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00741455

    Chemotherapy Followed by Allogeneic Stem Cell Transplantation for Hematologic Malignancies

    Not yet reported Dartmouth-Hitchcock Medical Center 18 participants Est. completion 2020-05-01 1 site Stand-alone
    Other conditions: Hematologic Malignancies
    View official trial listing →
  • Terminated NCT NCT00779142

    Utility of Intravitreal Methotrexate in Diabetic Macular Edema Resistant to Conventional Therapies

    Not yet reported Wake Forest University 2 participants Est. completion 2012-08 1 site
    Other conditions: Diabetic Macular Edema
    View official trial listing →
  • Terminated NCT NCT00779220

    A Study to Evaluate the Efficacy, Safety and Pharmacokinetics/Pharmacodynamics (PK/PD) of Ocrelizumab in Patients With Rheumatoid Arthritis

    Not yet reported Chugai Pharmaceutical 152 participants Est. completion 2015-03 7 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT00781469

    A Study to Evaluate the RNA Signature of Rheumatoid Arthritis From Synovium and Whole Blood

    Imperial College London 29 participants Est. completion 2010-10 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00791921

    Efficacy Confirmation Trial of CDP870 Without Coadministration of Methotrexate (MTX) in Japanese Rheumatoid Arthritis (RA)

    Not yet reported Otsuka Pharmaceutical Co., Ltd. 230 participants Est. completion 2010-01 7 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00809172

    Study of Methotrexate Efficacy Versus Cyclosporine in Moderate to Severe Atopic Dermatitis Patients

    Not yet reported Hospices Civils de Lyon 100 participants Est. completion 2012-04 1 site Stand-alone
    Other conditions: Atopic Dermatitis
    View official trial listing →
  • Completed NCT NCT00844298

    Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

    Not yet reported Asan Medical Center 91 participants Est. completion 2014-07 16 sites Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Terminated NCT NCT00845832

    A Study of Combination Treatment With MabThera (Rituximab) and RoActemra (Tocilizumab) Versus RoActemra in Patients With Rheumatoid Arthritis With an Incomplete Response to Methotrexate

    Not yet reported Hoffmann-La Roche 24 participants Est. completion 2013-03 24 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT00846703

    The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia

    Not yet reported Sun Yat-sen University 600 participants Est. completion 2018-12 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT00847613

    A 2-Year Phase 3 Study Of CP-690,550 In Patients With Active Rheumatoid Arthritis On Background Methotrexate

    Not yet reported Pfizer 800 participants Est. completion 2012-02 115 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Completed NCT NCT00847886

    Study of LX3305 and Methotrexate in Subjects With Stable Rheumatoid Arthritis

    Not yet reported Lexicon Pharmaceuticals 15 participants Est. completion 2009-03 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00866749

    Augmented Berlin-Frankfurt-Munster (BFM) Therapy for Adolescent/Young Adults With Acute Lymphoblastic Leukemia or Acute Lymphoblastic Lymphoma

    Not yet reported M.D. Anderson Cancer Center 120 participants Est. completion 2018-07-26 1 site Stand-alone
    Other conditions: Lymphoblastic Leukemia, Lymphoblastic Lymphoma
    View official trial listing →
  • Completed NCT NCT00867516

    Safety, Efficacy and Pharmacokinetics Study of ALD518 in Patients With Active Rheumatoid Arthritis

    Not yet reported CSL Behring 127 participants Est. completion 2009-12 26 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Terminated NCT NCT00882206

    Pre-reinductive Decitabine and Vorinostat in Relapsed Lymphoblastic Lymphoma or Acute Lymphoblastic Leukemia

    Not yet reported Masonic Cancer Center, University of Minnesota 15 participants Est. completion 2013-01 1 site Stand-alone
    Other conditions: Leukemia, Lymphoma
    View official trial listing →
  • Completed NCT NCT00905073

    Low Dose Cyclosporin and Methotrexate Therapy in Diabetes

    Not yet reported Georgetown University 8 participants Est. completion 1994-06 1 site Stand-alone
    Other conditions: Type 1 Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT00941707

    An Efficacy and Safety Study of JNJ-38518168 in Adult Participants With Rheumatoid Arthritis

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 86 participants Est. completion 2010-11 34 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT00967057

    Combination Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

    Not yet reported Children's Cancer and Leukaemia Group 470 participants Est. completion 2011-12 6 sites Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Status unknown NCT NCT00989352

    Methotrexate-based Chemo-immunotherapy Followed by Maintenance Therapy for Patients > 65 Years With Central Nervous System (CNS)-Lymphoma

    Not yet reported University Hospital Freiburg 56 participants Est. completion 2011-09 1 site
    Other conditions: Primary Non Hodgkin Lymphoma of the Central Nervous System
    View official trial listing →
  • Completed NCT NCT01001208

    The Efficacy and Safety of Adding Methotrexate to Etanercept in Psoriasis

    Not yet reported Amgen 478 participants Est. completion 2011-02 Stand-alone
    Other conditions: Psoriasis
    View official trial listing →
  • Completed NCT NCT01015547

    Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic Arthritis

    Not yet reported Helsinki University Central Hospital 60 participants Est. completion 2013-12 6 sites Stand-alone
    Other conditions: Juvenile Idiopathic Arthritis
    View official trial listing →
  • Completed NCT NCT01026519

    A Safety and Tolerability Study of REGN88(SAR153191) in Subjects With Rheumatoid Arthritis

    Not yet reported Regeneron Pharmaceuticals 32 participants Est. completion 2009-05 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01050998

    A Study to Evaluate the Efficacy and Safety of CAM-3001 (Drug) in Subjects With Rheumatoid Arthritis

    Not yet reported MedImmune LLC 516 participants Est. completion 2012-07-27 55 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT01067989

    Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast Cancer

    Not yet reported HaEmek Medical Center, Israel 22 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: Chemotherapy, Breast Cancer, Metastatic
    View official trial listing →
  • Completed NCT NCT01083342

    High-Dose (HD) Methotrexate (MTX) Induction Chemotherapy Followed by Alternative HD MTX-based and HD Cytarabine-based Combination Consolidation Chemotherapy for Newly Diagnosed Primary CNS Lymphoma; CISL 10-01 Study

    Not yet reported Samsung Medical Center 36 participants Est. completion 2012-05 1 site
    Other conditions: CNS Lymphoma
    View official trial listing →
  • Completed NCT NCT01085617

    Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia

    University College, London Est. completion 2025-02-24 Stand-alone
    Other conditions: Leukemia, Mucositis, Oral Complications
    View official trial listing →
  • Status unknown NCT NCT01087398

    Hematopoietic Stem Cell Transplantation for Malignant Infantile Osteopetrosis

    Not yet reported, Not yet reported Tehran University of Medical Sciences 10 participants Est. completion 2012-12 1 site Stand-alone
    Other conditions: Osteopetrosis
    View official trial listing →
  • Completed NCT NCT01093885

    Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis

    Not yet reported University of Pennsylvania 15 participants Est. completion 2016-07 1 site
    Other conditions: Systemic Sclerosis, Scleroderma
    View official trial listing →
  • Terminated NCT NCT01117129

    A Study of Efficacy of Rituximab [Mabthera/Rituxan] in Patients With Rheumatoid Arthritis Using Magnetic Resonance Imaging of the Hand (RESONAR)

    Not yet reported Hoffmann-La Roche 2 participants Est. completion 2010-06 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT01118013

    Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Malignancies or Secondary Myelodysplasia Previously Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant

    Not yet reported Alliance for Clinical Trials in Oncology 6 participants Est. completion 2013-08 10 sites Stand-alone
    Other conditions: Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
    View official trial listing →
  • Completed NCT NCT01162421

    A Canadian Study to Evaluate Early Use of Adalimumab After Methotrexate Failure in Early Rheumatoid Arthritis

    Not yet reported AbbVie (prior sponsor, Abbott) 77 participants Est. completion 2015-07 Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01164579

    Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)

    Not yet reported Pfizer 109 participants Est. completion 2013-11 40 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01185353

    A Study in Participants With Rheumatoid Arthritis on Background Methotrexate Therapy

    Not yet reported Eli Lilly and Company 301 participants Est. completion 2014-03 68 sites Stand-alone
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Completed NCT NCT01188798

    Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies

    Not yet reported St. Jude Children's Research Hospital 6 participants Est. completion 2012-02 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia, Chronic Myelocytic Leukemia, Hodgkin's Disease, Myelodysplastic Syndrome
    View official trial listing →
  • Terminated NCT NCT01198002

    A Rheumatoid Arthritis Study in Participants on a Background Treatment of Methotrexate

    Not yet reported Eli Lilly and Company 1041 participants Est. completion 2014-01 234 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT01217814

    Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers

    Not yet reported Sanofi 16 participants Est. completion 2011-09 14 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01238159

    Concomitant Chemo-radiotherapy Followed by MIDLE Chemotherapy in Stage I/II Extranodal NK/T-cell Lymphoma

    Not yet reported Samsung Medical Center 30 participants Est. completion 2014-12 1 site
    Other conditions: Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-Type
    View official trial listing →
  • Completed NCT NCT01248780

    Study of Subcutaneous Golimumab in Chinese Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy

    Not yet reported Centocor, Inc. 264 participants Est. completion 2012-07 9 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01256398

    Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

    Not yet reported National Cancer Institute (NCI) 66 participants Est. completion 2021-11-15 101 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
    View official trial listing →
  • Terminated NCT NCT01258634

    A Study of Pre-Operative Treatment of Newly-Diagnosed, Surgically-Resectable Osteosarcoma With Doxorubicin, Ifosfamide, Etoposide, and Cisplatin With Early Metabolic Assessment of Response

    Not yet reported University of Chicago 2 participants Est. completion 2011-11 1 site
    Obstructive sleep apnea Other conditions: Lung Metastases
    View official trial listing →
  • Completed NCT NCT01283399

    An Observational Study of Rituximab in Combination With Methotrexate in Participants With Active Rheumatoid Arthritis

    Hoffmann-La Roche 79 participants Est. completion 2014-04 5 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT01285310

    Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid Arthritis

    Not yet reported Amgen 237 participants Est. completion 2012-09-10 50 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01305655

    Glucarpidase Effect on Severe Delayed HDM-clearance in Children Treated With High-dose Mtx in ALL

    Not yet reported Nordic Society for Pediatric Hematology and Oncology 47 participants Est. completion 2014-12 5 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia (ALL)
    View official trial listing →
  • Completed NCT NCT01306474

    Observation on the Treg in the Uveitis Patients

    Xijing Hospital 30 participants Est. completion 2010-08 1 site
    Other conditions: Uveitis
    View official trial listing →
  • Completed NCT NCT01319981

    Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia

    Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2020-11-11 1 site Stand-alone
    Other conditions: Leukemia
    View official trial listing →
  • Completed NCT NCT01323920

    Bortezomib-based GVHD Prophylaxis After Allogeneic Transplant for Patients Without Matched Related Donors

    Not yet reported Dana-Farber Cancer Institute 35 participants Est. completion 2013-11 1 site Stand-alone
    Other conditions: Leukemia, Lymphoma, Myelodysplastic Syndrome
    View official trial listing →
  • Completed NCT NCT01328522

    Comparison of the Safety and Pharmacokinetics of Two SAR153191 (REGN88) Drug Products in Rheumatoid Arthritis Patients

    Not yet reported Sanofi 32 participants Est. completion 2011-09 4 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01360970

    Hepatitis A Vaccine in Patients With Immunomodulating Drugs

    Not yet reported Lars Rombo 68 participants Est. completion 2011-05 4 sites
    Other conditions: Response to Hepatitis A Vaccine
    View official trial listing →
  • Status unknown NCT NCT01366898

    Protocol For the Treatment Acute Lymphoblastic Leukemia With Ph 'Negative in Elderly Patients (> 55 Years)

    Not yet reported PETHEMA Foundation 100 participants Est. completion 2022-12 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT01379209

    Intravenous Administration of RGI-2001 in Patient Undergoing Allogenic Hematopoietic Stem Cell Transplantation (AHSCT)

    Not yet reported, Not yet reported Regimmune Corporation 68 participants Est. completion 2017-04 6 sites Stand-alone
    Other conditions: Graft Versus Host Disease
    View official trial listing →
  • Completed NCT NCT01384461

    An Observational Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (ACTIVATE)

    Hoffmann-La Roche 251 participants Est. completion 2013-05 20 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01412879

    S1106 Rituximab With Combination Chemotherapy or Bendamustine Hydrochloride Followed by Consolidation Chemotherapy and Stem Cell Transplantation in Older Patients With Previously Untreated Mantle Cell Lymphoma

    Not yet reported SWOG Cancer Research Network 53 participants Est. completion 2021-03 204 sites Stand-alone
    Other conditions: Lymphoma
    View official trial listing →
  • Active, not recruiting NCT NCT01424982

    Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

    Not yet reported M.D. Anderson Cancer Center 88 participants Est. completion 2027-10-31 1 site Stand-alone
    Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia, Adult Acute Lymphoblastic Leukemia in Complete Remission, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Philadelphia Chromosome Positive, Untreated Adult Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT01430507

    A Clinical Trial to Study the Effects of Revamilast in Patients With Rheumatoid Arthritis

    Not yet reported Glenmark Pharmaceuticals Ltd. India 406 participants Est. completion 2012-12 36 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01450982

    A Study to Investigate How JNJ-38518168 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis Participants

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 20 participants Est. completion 2011-10 4 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT01483690

    A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL

    Not yet reported, Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 23 participants Est. completion 2015-07-31 28 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Precursor B-Cell Lymphoblastic Leukemia, Precursor T-Cell Lymphoblastic Leukemia
    View official trial listing →
  • Status unknown NCT NCT01501149

    Treatment of Natural Killer/T Cell Lymphoma-Ⅲ/Ⅳ

    Not yet reported Mingzhi Zhang 80 participants Est. completion 2019-05 1 site Stand-alone
    Other conditions: Nasal and Nasal-type NK/T-cell Lymphoma
    View official trial listing →
  • Completed NCT NCT01516593

    Short Term Intensified Chemo-immunotherapy in HIV-positive Patients With Burkitt Lymphoma

    Not yet reported Andres J. M. Ferreri 19 participants Est. completion 2015-08 8 sites Stand-alone
    Other conditions: HIV, Burkitt's Lymphoma
    View official trial listing →
  • Completed NCT NCT01519791

    A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis

    Not yet reported UCB Pharma SA 880 participants Est. completion 2015-09 178 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01521923

    A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis

    Not yet reported UCB Pharma 359 participants Est. completion 2015-09 178 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01528163

    Study Comparing Two Treatments in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

    Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 101 participants Est. completion 2014-11 16 sites
    Other conditions: Squamous Cell Carcinoma of the Head and Neck
    View official trial listing →
  • Completed NCT NCT01554696

    A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects Who Have Had an Inadequate Response to Methotrexate

    Not yet reported Astellas Pharma Inc 379 participants Est. completion 2014-02-11 49 sites Stand-alone
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Completed NCT NCT01567358

    Study of NI-071 in Comparison With Remicade in Patients With Rheumatoid Arthritis

    Not yet reported Nichi-Iko Pharmaceutical Co., Ltd. 14 participants Est. completion 2013-04 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01572662

    Allogeneic Transplantation Using Timed Sequential Busulfan and Fludarabine Conditioning

    Not yet reported M.D. Anderson Cancer Center 201 participants Est. completion 2022-08-11 1 site Stand-alone
    Other conditions: Leukemia, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia, Myeloproliferative Diseases, Non-Hodgkins Lymphoma, Hodgkins Lymphoma, Multiple Myeloma, Myelodysplastic Syndrome
    View official trial listing →
  • Completed NCT NCT01578850

    Study Conducted in Subjects With Rheumatoid Arthritis Who Have Moderate to Severe Disease Activity Despite Methotrexate Therapy With or Without Other Non Biologic Disease Modifying Antirheumatic Drugs (DMARDs)for at Least 12 Weeks Prior to Screening

    Not yet reported Pfizer 491 participants Est. completion 2015-03 62 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT01629511

    Allogeneic Stem Cell Transplant for CLL

    Not yet reported, Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2018-04-25 1 site Stand-alone
    Other conditions: Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia, Richter Syndrome
    View official trial listing →
  • Status unknown NCT NCT01633983

    Methotrexate for Central Serous Chorioretinopathy Treatment Trial

    Not yet reported Edward Averbukh 20 participants Est. completion 2015-07 1 site Stand-alone
    Other conditions: Central Serous Chorioretinopathy
    View official trial listing →
  • Completed NCT NCT01646385

    Study to Assess the Safety and Efficacy of Etanercept in Patients Treated Over the Long-term in Real-world Clinical Practice, Using Data Collected by the British Society of Rheumatology Biologics Registry

    Pfizer 6393 participants Est. completion 2012-08
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01654575

    Methotrexate in Symptomatic Knee Osteoarthritis

    Not yet reported University of Alexandria 88 participants Est. completion 2012-01 1 site Stand-alone
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT01662167

    Comparison of Single and Multiple-dose Methotrexate Therapy for Ectopic Pregnancy

    Not yet reported Hormozgan University of Medical Sciences 87 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Pregnancy, Ectopic
    View official trial listing →
  • Completed NCT NCT01665677

    Atorvastatin as GVHD Prophylaxis for Allogeneic Hematopoietic Cell Transplantation

    Not yet reported Mehdi Hamadani 69 participants Est. completion 2021-07-09 2 sites
    Other conditions: Graft vs Host Disease
    View official trial listing →
  • Completed NCT NCT01668641

    Dose-ranging Study With GLPG0634 in Methotrexate-refractory Active Rheumatoid Arthritis Patients

    Not yet reported Lakefront Biotherapeutics NV 91 participants Est. completion 2012-10 19 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT01679951

    A Dose Range Finding Study of JNJ-38518168 in Patients With Active Rheumatoid Arthritis in Spite of Treatment With Methotrexate

    Not yet reported Janssen Research & Development, LLC 272 participants Est. completion 2014-07-03 85 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01700946

    Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma

    Not yet reported St. Jude Children's Research Hospital 80 participants Est. completion 2021-07-24 3 sites
    Other conditions: Recurrent B-Cell Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood B-Lymphoblastic Lymphoma
    View official trial listing →
  • Completed NCT NCT01706926

    A Study of Mavrilimumab in Subjects With Moderate-to-Severe Rheumatoid Arthritis

    Not yet reported MedImmune LLC 420 participants Est. completion 2014-01 42 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01711359

    A Study in Participants With Moderate to Severe Rheumatoid Arthritis

    Not yet reported Eli Lilly and Company 588 participants Est. completion 2015-08 154 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01737671

    Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study

    Not yet reported M.D. Anderson Cancer Center 7 participants Est. completion 2018-01-11 2 sites Stand-alone
    Other conditions: Brain Tumor, Malignant Neoplasm of Fourth Ventricle of Brain
    View official trial listing →
  • Completed NCT NCT01743131

    Abatacept as GVHD Prophylaxis Phase 2

    Not yet reported Boston Children's Hospital 186 participants Est. completion 2024-03-30 14 sites Stand-alone
    Other conditions: Graft vs Host Disease, Malignancy
    View official trial listing →
  • Completed NCT NCT01745055

    Co-Administration Of Methotrexate And CP-690,550

    Not yet reported Pfizer 12 participants Est. completion 2006-06 4 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01751997

    Family-mismatched/Haploidentical Donors Versus Matched Unrelated Donors

    Not yet reported, Not yet reported Byung-Sik Cho 116 participants Est. completion 2019-12-31 1 site Stand-alone
    Other conditions: Acute Myeloid Leukemia
    View official trial listing →
  • Completed NCT NCT01760226

    Dose Adjusted EPOCH-R, to Treat Mature B Cell Malignancies

    Not yet reported Baylor College of Medicine 4 participants Est. completion 2016-12 1 site Stand-alone
    Other conditions: Diffuse Large B Cell Lymphoma, Post Transplant Lymphoproliferative Disorder, Primary Mediastinal (Thymic) Large B-cell Lymphoma
    View official trial listing →
  • Terminated NCT NCT01764997

    An Evaluation of Sarilumab Plus Methotrexate Compared to Etanercept Plus Methotrexate in RA Patients Not Responding to Adalimumab Plus Methotrexate

    Not yet reported Sanofi 776 participants Est. completion 2015-01 257 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT01773395

    GVAX vs. Placebo for MDS/AML After Allo HSCT

    Not yet reported Dana-Farber Cancer Institute 123 participants Est. completion 2021-11-24 4 sites
    Other conditions: Myelodysplastic Syndrome, Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia
    View official trial listing →
  • Completed NCT NCT01782339

    A Novel Single Arm Phase II Study for Relapsed Germ Cell Tumours With Poor Prognosis

    Not yet reported Barts & The London NHS Trust 45 participants Est. completion 2021-05-05 1 site Stand-alone
    Other conditions: Germ Cell Tumour
    View official trial listing →
  • Terminated NCT NCT01783015

    Study of Etanercept in Subjects With Rheumatoid Arthritis Who Have Had an Inadequate Response to Adalimumab or Infliximab Plus Methotrexate

    Not yet reported Pfizer 16 participants Est. completion 2014-08 15 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01785810

    Phase II Maraviroc for GVHD Prevention

    Not yet reported Abramson Cancer Center at Penn Medicine 37 participants Est. completion 2018-07-12 1 site Stand-alone
    Other conditions: Hematologic Malignancy
    View official trial listing →
  • Terminated NCT NCT01802593

    Comparison of 2 Immunomodulator Withdrawal Schemes for Infliximab Monotherapy in Active Pediatric Crohn's Disease After Thiopurine Failure

    Not yet reported Prof. Arie Levine 20 participants Est. completion 2015-12 1 site Stand-alone
    Other conditions: Crohn's Disease
    View official trial listing →
  • Completed NCT NCT01813617

    Outcome in Patients With Recent Onset Polymyositis and Dermatomyositis

    Karolinska University Hospital 72 participants 1 site
    Other conditions: Polymyositis, Dermatomyositis
    View official trial listing →
  • Status unknown NCT NCT01823315

    Methotrexate Single-dose Treatment and Methotrexate/Actinomycin-D Single-dose Treatment in Low-Risk Gestational Trophoblastic Neoplasia

    Not yet reported Ding Ma 300 participants Est. completion 2019-12 3 sites Stand-alone
    Other conditions: Gestational Trophoblastic Disease, Gestational Trophoblastic Neoplasia, Gestational Trophoblastic Tumor, Gestational Trophoblastic Neoplasms
    View official trial listing →
  • Completed NCT NCT01850121

    Remicade in the Treatment of Patients With Active Ankylosing Spondylitis

    Göteborg University 19 participants Est. completion 2008-05 1 site
    Other conditions: Ankylosing Spondylitis
    View official trial listing →
  • Completed NCT NCT01855568

    Methotrexate Treatment for Ectopic Pregnancy

    Not yet reported CHA University 92 participants Est. completion 2015-04 1 site Stand-alone
    Other conditions: Ectopic Pregnancy
    View official trial listing →
  • Completed NCT NCT01856478

    LUX-Head&Neck 3: Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy

    Not yet reported Boehringer Ingelheim 340 participants Est. completion 2024-10-02 53 sites
    Other conditions: Head and Neck Neoplasms
    View official trial listing →
  • Terminated NCT NCT01862224

    A Synovial Biopsy Study of JNJ-38518168 in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy

    Not yet reported Janssen Research & Development, LLC 21 participants Est. completion 2014-07 2 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01884623

    Phase III Trial Comparing Methotrexate and Cetuximab in First-line Treatment of Recurrent and/or Metastatic Squamous Cell Head and Neck Cancer

    Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 82 participants Est. completion 2021-10-12 1 site
    Other conditions: Head Neck Cancer Squamous Cell Recurrent
    View official trial listing →
  • Completed NCT NCT01884636

    A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Methotrexate

    Not yet reported Astellas Pharma Global Development, Inc. 24 participants Est. completion 2013-03 1 site Stand-alone
    Other conditions: Pharmacokinetics of Isavuconazole, Pharmacokinetics of Methotrexate, Pharmacokinetics of 7-hydroxymethotrexate, Healthy Subjects
    View official trial listing →
  • Completed NCT NCT01896752

    Renal and Hepatic Clearance Following High-Dose Methotrexate in Childhood ALL

    Rigshospitalet, Denmark 43 participants Est. completion 2013-01 1 site
    Other conditions: Lymphoblastic Leukemia, Acute, Childhood
    View official trial listing →
  • Withdrawn NCT NCT01903317

    Evaluation of Vitamin D Levels in Psoriasis Patients

    University of California, Irvine Est. completion 2015-07 1 site
    Other conditions: Psoriasis
    View official trial listing →
  • Completed NCT NCT01914770

    Effectiveness of Belimumab Treatment in a Subpopulation of Systemic Lupus Erythematosus (SLE) Patients: a Pooled Analysis of BLISS-52 and BLISS-76

    GlaxoSmithKline 1016 participants Est. completion 2010-11
    Other conditions: Systemic Lupus Erythematosus
    View official trial listing →
  • Status unknown NCT NCT01933282

    MESA Treatment for NK/T Cell Lymphoma

    Not yet reported Air Force Military Medical University, China 100 participants Est. completion 2015-01 1 site Stand-alone
    Other conditions: Lymphoma, Extranodal NK-T-Cell
    View official trial listing →
  • Completed NCT NCT01941095

    A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid Arthritis

    Not yet reported Hoffmann-La Roche 100 participants Est. completion 2016-07-10 10 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01949116

    Safety and Effectiveness of Low-Dose Methotrexate for Reducing Inflammation in HIV-Infected Adults on ARV Medications

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 176 participants Est. completion 2016-12-08 22 sites Stand-alone
    Other conditions: HIV Infections
    View official trial listing →
  • Terminated NCT NCT01964755

    Chemotherapy for Relapsed Epstein Barr Virus Associated Lymphoma

    Not yet reported University of Miami 6 participants Est. completion 2018-06-07 2 sites Stand-alone
    Other conditions: Epstein Barr Virus Associated Non Hodgkin's Lymphoma, Epstein Barr Virus Associated Hodgkin's Lymphoma, Post-Transplant Lymphoproliferative Disease
    View official trial listing →
  • Completed NCT NCT01976182

    Prospective, Multicentric, Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (methotrexate, Cyclophosphamide) in Large Granular Lymphocytes Leukemia

    Not yet reported Rennes University Hospital 166 participants Est. completion 2024-10-07 59 sites
    Other conditions: Large Granular Lymphocytes Leukemia
    View official trial listing →
  • Completed NCT NCT01979536

    Brentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma

    Not yet reported National Cancer Institute (NCI) 137 participants Est. completion 2024-03-31 154 sites Stand-alone
    Other conditions: Anaplastic Large Cell Lymphoma, ALK-Positive, Ann Arbor Stage II Noncutaneous Childhood Anaplastic Large Cell Lymphoma, Ann Arbor Stage III Noncutaneous Childhood Anaplastic Large Cell Lymphoma, Ann Arbor Stage IV Noncutaneous Childhood Anaplastic Large Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT01984099

    RCT on the Efficacy of Methotrexate for the Prevention of GTD

    Not yet reported University of the Philippines 99 participants Est. completion 2013-08 1 site
    Other conditions: Hydatidiform Mole
    View official trial listing →
  • Terminated NCT NCT01984268

    ACTHAR for Acute Treatment of Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate

    Not yet reported Dartmouth-Hitchcock Medical Center 15 participants Est. completion 2016-09-01 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT01998906

    A Study of Herceptin (Trastuzumab) in Combination Chemotherapy in Women With Locally Advanced Breast Cancer

    Not yet reported Hoffmann-La Roche 330 participants Est. completion 2012-07 36 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT02003222

    Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

    Not yet reported National Cancer Institute (NCI) 488 participants Est. completion 2027-02-25 544 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
    View official trial listing →
  • Completed NCT NCT02011022

    Pharmacokinetic Analysis of High Dose Methotrexate in Pediatric Lymphoblastic Malignancies

    Not yet reported The Children's Hospital of Zhejiang University School of Medicine 291 participants Est. completion 2010-02 1 site
    Other conditions: Methotrexate Adverse Reaction
    View official trial listing →
  • Completed NCT NCT02045368

    Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R

    Not yet reported IGF Oncology, LLC 92 participants Est. completion 2016-09-30 1 site Stand-alone
    Other conditions: Breast Cancer, Brain Cancer, Gastrointestinal Cancers, Genitourinary Cancers, Gynecologic Cancers, Head and Neck Cancers, Melanoma, Thoracic Cancers
    View official trial listing →
  • Status unknown NCT NCT02087696

    Uncontrolled Study to Evaluate Efficacy of Tocilizumab in Patients With Moderate or Severe Rheumatoid Arthritis

    Not yet reported Spanish Foundation of Rheumatology 122 participants Est. completion 2016-07 20 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Completed NCT NCT02097173

    Bioavailability in Patient With Psoriasis: Metoject Prefilled Pen

    Not yet reported medac GmbH 35 participants 1 site
    Other conditions: Psoriasis
    View official trial listing →
  • Active, not recruiting NCT NCT02101853

    Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

    Not yet reported National Cancer Institute (NCI) 669 participants Est. completion 2026-09-16 186 sites Stand-alone
    Other conditions: Recurrent B Acute Lymphoblastic Leukemia
    View official trial listing →
  • Active, not recruiting NCT NCT02112916

    Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

    Not yet reported National Cancer Institute (NCI) 847 participants Est. completion 2026-09-16 212 sites Stand-alone
    Other conditions: Adult T Acute Lymphoblastic Leukemia, Ann Arbor Stage II Adult Lymphoblastic Lymphoma, Ann Arbor Stage II Childhood Lymphoblastic Lymphoma, Ann Arbor Stage III Adult Lymphoblastic Lymphoma, Ann Arbor Stage III Childhood Lymphoblastic Lymphoma, Ann Arbor Stage IV Adult Lymphoblastic Lymphoma, Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma, Childhood T Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT02115750

    Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Rheumatoid Arthritis (RA)

    Not yet reported Coherus Oncology, Inc. 647 participants Est. completion 2016-05 141 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02122081

    Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

    Not yet reported Sumithira Vasu 33 participants Est. completion 2022-09-06 1 site Stand-alone
    Other conditions: Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid Leukemia
    View official trial listing →
  • Completed NCT NCT02141997

    A Study to Investigate the Safety and Efficacy of ABT-122 Given With Methotrexate in Subjects With Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate

    Not yet reported AbbVie 222 participants Est. completion 2015-11
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02151851

    A Study of Certolizumab Pegol as Additional Therapy in Chinese Patients With Active Rheumatoid Arthritis

    Not yet reported UCB Pharma SA, Belgium 430 participants Est. completion 2016-06 30 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT02174354

    Methotrexate Polyglutamates as a Marker of Clinical Response and Toxicity in the Treatment of Psoriasis

    King's College London 350 participants Est. completion 2018-08 1 site
    Other conditions: Psoriasis Chronic, Injury of Liver
    View official trial listing →
  • Completed NCT NCT02187055

    An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With Methotrexate

    Not yet reported Pfizer 1152 participants Est. completion 2016-12 215 sites Stand-alone
    Other conditions: Rhematoid Arthritis
    View official trial listing →
  • Completed NCT NCT02200978

    A Study for Improving the Outcome of Childhood Acute Promyeloid Leukemia

    Not yet reported South China Children's Leukemia Group 176 participants Est. completion 2021-10 1 site
    Other conditions: Childhood Acute Promyelocytic Leukemia
    View official trial listing →
  • Completed NCT NCT02219347

    Biomarkers of Remission in Rheumatoid Arthritis (BioRRA)

    Not yet reported Newcastle-upon-Tyne Hospitals NHS Trust 74 participants Est. completion 2017-08 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02228772

    Phase I Study of MLN 9708 in Addition to Chemotherapy for the Treatment of Acute Lymphoblastic Leukemia in Older Adults

    Not yet reported Massachusetts General Hospital 19 participants Est. completion 2019-11 3 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, B-cell Adult Acute Lymphoblastic Leukemia, T-cell Adult Acute Lymphoblastic Leukemia
    View official trial listing →
  • Status unknown NCT NCT02273583

    Prospective Clinical Trial Evaluating Metronomic Chemotherapy in Patients With High-grade, Operable, Non-metastatic Osteosarcoma of the Extremity

    Not yet reported Grupo de Apoio ao Adolescente e a Crianca com Cancer 738 participants 1 site Stand-alone
    Obstructive sleep apnea
    View official trial listing →
  • Active, not recruiting NCT NCT02299999

    SAFIR02_Breast - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breast Cancer

    Not yet reported UNICANCER 1460 participants Est. completion 2025-12 25 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT02313922

    Optimizing Psoriasis Treatment of Etanercept Combined Methotrexate

    Not yet reported Zhejiang University 466 participants Est. completion 2018-08 1 site Stand-alone
    Other conditions: Psoriasis
    View official trial listing →
  • Completed NCT NCT02330380

    Comparative Effectiveness of Psoriasis Treatments on Systemic Inflammation

    University Hospitals Cleveland Medical Center 26 participants Est. completion 2016-12 1 site
    Other conditions: Psoriasis, Inflammation
    View official trial listing →
  • Completed NCT NCT02378298

    Rituximab (RTX) Therapy in Patients With Active TAO

    Not yet reported Göteborg University 38 participants Est. completion 2020-02-01 5 sites
    Other conditions: Ophthalmopathy, Thyroid-Associated
    View official trial listing →
  • Completed NCT NCT02379091

    Dose Finding Study of Namilumab in Combination With Methotrexate in Participants With Moderate to Severe Rheumatoid Arthritis (RA)

    Not yet reported Takeda 108 participants Est. completion 2016-12-05 31 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT02383680

    Yellow Fever Vaccination Under Low Dose Methotrexate Therapy

    University of Zurich 30 participants Est. completion 2016-06 6 sites
    Other conditions: Rheumatic, Dermatologic Disorders
    View official trial listing →
  • Completed NCT NCT02383901

    A Retrospective Non-intervention Study to Characterize FOlate Rescue Treatment in Osteosarcoma Patients Treated With HDMTX

    Isofol Medical AB 116 participants Est. completion 2016-05 5 sites
    Obstructive sleep apnea
    View official trial listing →
  • Status unknown NCT NCT02396043

    Modified BFM-95 Regimen as First-Line Chemotherapy in Adults With T- Lymphoblastic Lymphoma

    Not yet reported Sun Yat-sen University 50 participants Est. completion 2025-03 1 site Stand-alone
    Other conditions: Lymphoma, Lymphoblastic
    View official trial listing →
  • Completed NCT NCT02405780

    A Study to Compare FKB327 Long-term Safety, Efficacy and Immunogenicity With Humira® in Rheumatoid Arthritis Patients

    Not yet reported Fujifilm Kyowa Kirin Biologics Co., Ltd. 645 participants Est. completion 2018-01-18 92 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Terminated NCT NCT02413047

    Evaluate if Response to Infliximab or Adalimumab May be Regained With an Immunomodulator

    Not yet reported Indiana University 3 participants Est. completion 2018-02 1 site Stand-alone
    Other conditions: Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's Disease
    View official trial listing →
  • Terminated NCT NCT02429895

    A Phase 2, Multicenter Open-Label Extension (OLE) Study With ABT-122 in Active Psoriatic Arthritis Subjects Who Have Completed a Preceding Study M14-197

    Not yet reported AbbVie 168 participants Est. completion 2016-05 36 sites
    Other conditions: Psoriatic Arthritis
    View official trial listing →
  • Completed NCT NCT02433340

    Phase 2, Multicenter, Open-Label Extension Study With ABT-122 in Rheumatoid Arthritis Subjects Who Have Completed the Preceding M12-963 Study

    Not yet reported AbbVie 158 participants Est. completion 2016-05
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02456844

    Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy Patients

    Not yet reported Bristol-Myers Squibb 24 participants Est. completion 2015-07 Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02467504

    Low-dose Recombinant Human IL-2 for the Treatment of Rheumatoid Arthritis

    Not yet reported Peking University People's Hospital 47 participants Est. completion 2017-08-31 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT02525172

    Immune Modulation Therapy for Pompe Disease

    Not yet reported National Taiwan University Hospital 8 participants Est. completion 2020-07 1 site Stand-alone
    Other conditions: Pompe Disease
    View official trial listing →
  • Terminated NCT NCT02531633

    Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis

    Not yet reported GlaxoSmithKline 161 participants Est. completion 2018-03-21 63 sites Stand-alone
    Other conditions: Giant Cell Arteritis
    View official trial listing →
  • Completed NCT NCT02557100

    Study to Assess Changes in the Immune Profile in Adults With Early Rheumatoid Arthritis

    Not yet reported Bristol-Myers Squibb 80 participants Est. completion 2019-03-28 28 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02576067

    Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study

    Not yet reported Icahn School of Medicine at Mount Sinai 123 participants Est. completion 2019-03-29 3 sites Stand-alone
    Cardiovascular disease Other conditions: Vascular Inflammation
    View official trial listing →
  • Status unknown NCT NCT02644044

    Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study

    Not yet reported Tel-Aviv Sourasky Medical Center 30 participants Est. completion 2018-01 Stand-alone
    Other conditions: To Evaluate the Effect of Therapy With IT MTX on the Disease Course of Patients With Progressive MS
    View official trial listing →
  • Terminated NCT NCT02647762

    CF101 Therapy Compared to Methotrexate Therapy for Active Rheumatoid Arthritis

    Not yet reported Can-Fite BioPharma 244 participants Est. completion 2020-11-30 35 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02698657

    A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASP5094 Following Multiple Intravenous Doses in Subjects With Rheumatoid Arthritis on Methotrexate

    Not yet reported Astellas Pharma Global Development, Inc. 30 participants Est. completion 2017-09-07 13 sites
    Other conditions: Rheumatoid Arthritis (RA)
    View official trial listing →
  • Terminated NCT NCT02701517

    Cyclosporine Plus Methotrexate or Alemtuzumab

    Not yet reported Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea 72 participants Est. completion 2009-11 5 sites
    Other conditions: Unrecognized Condition: Mature B or T-cell Neoplasm
    View official trial listing →
  • Completed NCT NCT02746380

    A Study Comparing LBAL to Humira® in Subjects With Active Rheumatoid Arthritis Despite Methotrexate Therapy

    Not yet reported LG Life Sciences 383 participants Est. completion 2018-02-23 2 sites
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Completed NCT NCT02748785

    MTX Discontinuation and Vaccine Response

    Not yet reported Seoul National University Hospital 277 participants Est. completion 2016-08 1 site Stand-alone
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Withdrawn NCT NCT02786563

    Changes in Ultrasonographic Assessment of Inflammation Upon Initiation of Adalimumab Combination Therapy in Chinese Rheumatoid Arthritis (RA) Patients With Inadequate Response to Methotrexate

    AbbVie Est. completion 2018-11-21 4 sites
    Other conditions: Rheumatoid Arthritis (RA)
    View official trial listing →
  • Completed NCT NCT02788201

    Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma

    Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2019-10-23 1 site Stand-alone
    Other conditions: Urothelial Carcinoma, Bladder Cancer, Urinary Bladder Neoplasms
    View official trial listing →
  • Completed NCT NCT02814175

    A Study of Subjects With Psoriatic Arthritis to Investigate the Effectiveness of Adalimumab Introduction Compared With Methotrexate Dose Escalation (CONTROL)

    Not yet reported AbbVie 246 participants Est. completion 2020-03-19 60 sites Stand-alone
    Other conditions: Psoriatic Arthritis
    View official trial listing →
  • Completed NCT NCT02833350

    Safety and Efficacy Study of GDC-0853 Compared With Placebo and Adalimumab in Participants With Rheumatoid Arthritis (RA)

    Not yet reported Genentech, Inc. 578 participants Est. completion 2018-07-02 150 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02879643

    Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy

    Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 29 participants Est. completion 2024-12-31 35 sites Stand-alone
    Other conditions: ALL, Childhood, Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Leukemia, Acute
    View official trial listing →
  • Completed NCT NCT02881086

    Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment

    Not yet reported Goethe University 1023 participants Est. completion 2024-12 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma
    View official trial listing →
  • Status unknown NCT NCT02894645

    Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study

    Not yet reported National University Hospital, Singapore 500 participants 4 sites
    Other conditions: Acute Lymphoblastic Leukemia (ALL)
    View official trial listing →
  • Status unknown NCT NCT02897011

    2-week dc of MTX and Influenza Vaccination in RA

    Not yet reported Seoul National University Hospital 318 participants Est. completion 2017-08 3 sites Stand-alone
    Other conditions: Rheumatoid Arthritis, Influenza, Methotrexate
    View official trial listing →
  • Completed NCT NCT02897817

    Treatment Adherence to Injectable Methotrexate in Rheumatoid Arthritis

    Nordic Pharma SAS 471 participants Est. completion 2017-12 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02926560

    Study Medication Adherence and Its Determinants in Chronic Disease Through the Example of Methotrexate in Chronic Inflammatory Rheumatism

    Centre Hospitalier Universitaire de Nīmes 137 participants Est. completion 2018-05-30 1 site
    Other conditions: Rheumatic Diseases
    View official trial listing →
  • Terminated NCT NCT02930343

    Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate Monotherapy

    Not yet reported Jawaharlal Institute of Postgraduate Medical Education & Research 136 participants Est. completion 2018-08 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02960438

    A Dose Response Study of E6011 in Participants With Rheumatoid Arthritis Inadequately Responding to Methotrexate

    Not yet reported Eisai Co., Ltd. 273 participants Est. completion 2019-09-17 90 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Active, not recruiting NCT NCT02981628

    Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

    Not yet reported Children's Oncology Group 80 participants Est. completion 2026-12-31 157 sites Stand-alone
    Other conditions: Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma, Refractory B Acute Lymphoblastic Leukemia, Refractory B Lymphoblastic Lymphoma
    View official trial listing →
  • Completed NCT NCT02986503

    European Study in Bone Sarcoma Patients Over 40 Years

    Italian Sarcoma Group 100 participants Est. completion 2016-11 3 sites
    Obstructive sleep apnea Other conditions: Spindle Cell Sarcoma of Bone
    View official trial listing →
  • Terminated NCT NCT03001219

    A Study of RO7123520 to Evaluate the Safety and Efficacy in Participants With Moderately To Severely Active Rheumatoid Arthritis (RA) Who Are Inadequately Responding to Anti-Tumor Necrosis Factor (TNF)-Alpha Therapy

    Not yet reported Hoffmann-La Roche 109 participants Est. completion 2018-11-06 81 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT03011281

    Effectiveness and Safety of Tofacitinib in Korean Patients With Rheumatoid Arthritis

    Hanyang University 378 participants Est. completion 2021-12 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT03016013

    A Study of the Efficacy and Safety of TACI-antibody Fusion Protein Injection (RC18) in Subjects with Inadequate Response to MTX Due to Treat Moderate and Severe Rheumatoid Arthritis.

    Not yet reported RemeGen Co., Ltd. 479 participants Est. completion 2022-12-29 1 site
    Other conditions: Moderate and Severe RheumatoId Arthritis
    View official trial listing →
  • Completed NCT NCT03123887

    Evaluate the Hematological Remission Rates and Survival Among Chinese Adult Patients With B-precursor ALL

    Harbin Hematology and Oncology Institute 632 participants Est. completion 2016-10-10 1 site
    Other conditions: B-precursor Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT03131973

    Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin

    Not yet reported Bristol-Myers Squibb 26 participants Est. completion 2017-11-10 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Terminated NCT NCT03175978

    IGF-MTX Conjugate in the Treatment of Myelodysplastic Syndrome

    Not yet reported, Not yet reported IGF Oncology, LLC 2 participants Est. completion 2021-09-30 2 sites Stand-alone
    Other conditions: Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic, Anemia, Refractory, With Excess of Blasts
    View official trial listing →
  • Completed NCT NCT03244462

    Food Effect, Oral & Intravenous Pharmacokinetics and Absolute Bioavailability of BAY1834845 Including Drug-drug Interaction With Methotrexate

    Not yet reported Bayer 10 participants Est. completion 2018-07-20 1 site Stand-alone
    Other conditions: Inflammation
    View official trial listing →
  • Completed NCT NCT03320928

    Skin Disease and Pulmonary Mortality After Transplantation

    Karolinska University Hospital 79 participants Est. completion 2016-11-24
    Other conditions: Pulmonary Mortality, Acute GVH Disease
    View official trial listing →
  • Completed NCT NCT03327116

    Effect of Methotrexate on Inflammatory Response in Adult Atopic Dermatitis Patients

    Not yet reported University of Sao Paulo General Hospital 10 participants Est. completion 2018-12-01 1 site Stand-alone
    Other conditions: Atopic Dermatitis
    View official trial listing →
  • Status unknown NCT NCT03408210

    Total Marrow and Lymphoid Irradiation and Chemotherapy for Myelodysplastic Syndrome or Acute Leukemia

    Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 191 participants Est. completion 2022-08 1 site Stand-alone
    Other conditions: Myelodysplastic Syndromes, Acute Leukemia
    View official trial listing →
  • Status unknown NCT NCT03408223

    Total Marrow and Lymphoid Irradiation and Chemotherapy for High-Risk Acute Leukemia

    Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 100 participants Est. completion 2022-12 1 site Stand-alone
    Other conditions: Acute Leukemia
    View official trial listing →
  • Completed NCT NCT03472274

    Durvalumab (MEDI4736) and TREmelimumab in NEOadjuvant Bladder Cancer Patients (DUTRENEO)

    Not yet reported Fundacion CRIS de Investigación para Vencer el Cáncer 101 participants Est. completion 2023-04-12 11 sites
    Other conditions: Bladder Cancer
    View official trial listing →
  • Completed NCT NCT03522415

    Study of Safety and Efficacy of HLX01+MTX in Patients With Rheumatoid Arthritis

    Not yet reported Shanghai Henlius Biotech 275 participants Est. completion 2020-09-11 1 site Stand-alone
    Other conditions: Moderately to Severely Active Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT03564704

    Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL

    Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 80 participants Est. completion 2021-05-30 1 site Stand-alone
    Other conditions: Leukemia, Leukemia, Acute, Adult Lymphoblastic Lymphoma, Leukemia, Lymphoblastic, Leukemia, T Cell, Adult Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Lymphoblastic Leukemia
    View official trial listing →
  • Status unknown NCT NCT03582254

    Role of [18F]-FDG Brain PET in Newly Diagnosed Primary Cerebral Lymphoma, in Immunocompetent Patient Older Than 60 Years

    Not yet reported Assistance Publique - Hôpitaux de Paris 62 participants Est. completion 2023-05-12 1 site Stand-alone
    Other conditions: Primary Central Nervous System Lymphoma
    View official trial listing →
  • Status unknown NCT NCT03599960

    Combination Chemotherapy in Patients With Newly Diagnosed BPDCN

    Not yet reported Centre Hospitalier Universitaire de Besancon 26 participants Est. completion 2024-11 2 sites Stand-alone
    Other conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
    View official trial listing →
  • Active, not recruiting NCT NCT03613532

    Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN

    Not yet reported Jacqueline Garcia, MD 102 participants Est. completion 2030-03-05 1 site Stand-alone
    Other conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), MDS/Myeloproliferative Neoplasm-unclassifiable (MDS/MPN-unclassifiable), Hematopoietic Stem Cell Transplant
    View official trial listing →
  • Completed NCT NCT03652961

    Rheumatoid Arthritis Memory B Cells and Abatacept

    Not yet reported NYU Langone Health 25 participants Est. completion 2021-09-27 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT03674424

    Avelumab as Neoadjuvant Therapy in Subjects With Urothelial Muscle Invasive Bladder Cancers (AURA Trial)

    Not yet reported Jules Bordet Institute 137 participants Est. completion 2025-01-30 10 sites Stand-alone
    Other conditions: Non-metastatic Muscle Invasive Bladder Cancer
    View official trial listing →
  • Status unknown NCT NCT03692416

    The Effect of Some Drugs Used in Treatment of Vasculitis on the Complement System in Children

    Not yet reported Assiut University 70 participants Est. completion 2022-05-11 1 site
    Other conditions: Vasculitis
    View official trial listing →
  • Completed NCT NCT03696173

    Safety Study of Abatacept in Rheumatoid Arthritis Participants

    Bristol-Myers Squibb 5800 participants Est. completion 2018-06-29 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT03736044

    Reconstitution of CD4+CD25highCD127low/-Tcell

    Not yet reported University Hospital of Ferrara 48 participants Est. completion 2017-03-13
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT03757364

    Methotrexate in the Treatment of Distal Interphalangeal Joint Extensor Tendon Enthesopathy in Nail Psoriasis

    Ryszard Górecki 32 participants Est. completion 2018-09-30 1 site
    Other conditions: Nail Psoriasis
    View official trial listing →
  • Completed NCT NCT03760003

    Dose-Ranging Phase 2b Study of ABX464 in Moderate to Severe Ulcerative Colitis

    Not yet reported Abivax S.A. 355 participants Est. completion 2021-04-16 130 sites
    Other conditions: Ulcerative Colitis
    View official trial listing →
  • Active, not recruiting NCT NCT03769506

    ASP-1929 Photoimmunotherapy (PIT) Study in Recurrent Head/Neck Cancer for Patients Who Have Failed at Least Two Lines of Therapy

    Not yet reported Rakuten Medical, Inc. 135 participants Est. completion 2025-12 22 sites
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Completed NCT NCT03775824

    Faecal Analyses in Rheumatoid Arthritis Therapy

    Region Skane 50 participants Est. completion 2019-06-01
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Active, not recruiting NCT NCT03817320

    PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

    Not yet reported, Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 24 participants Est. completion 2025-06-30 18 sites Stand-alone
    Other conditions: ALL, Childhood, Lymphoblastic Lymphoma, Childhood, Lymphoblastic Leukemia, Acute, Childhood
    View official trial listing →
  • Completed NCT NCT03830203

    Comparative Study of BAT1806 to RoActemra® in Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate

    Not yet reported Bio-Thera Solutions 621 participants Est. completion 2021-01-05 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT03833271

    The Efficacy of Influenza Vaccine Program in Children With Juvenile Idiopathic Arthritis. A Single Centre Results From Hungary

    Not yet reported University of Pecs 62 participants Est. completion 2019-09-30 1 site
    Other conditions: Juvenile Idiopathic Arthritis
    View official trial listing →
  • Status unknown NCT NCT03860012

    Folic Acid in Pediatric Inflammatory Bowel Disease

    Not yet reported Le Bonheur Children's Hospital 100 participants Est. completion 2020-05-01 1 site
    Other conditions: Inflammatory Bowel Diseases
    View official trial listing →
  • Terminated NCT NCT03860844

    Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia

    Not yet reported Sanofi 67 participants Est. completion 2023-05-26 41 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
    View official trial listing →
  • Completed NCT NCT03885037

    Infliximab Biosimilar for Intravenous Drip Infusion 100 mg "Pfizer" Drug Use Investigation (Rheumatoid Arthritis)

    Pfizer 77 participants Est. completion 2024-11-29 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT03904680

    Studying the Effect of Methotrexate Alone Versus Methotrexate and Vitamin D on the Cardiovascular Risk of Psoriatic Patients

    Not yet reported Cairo University 30 participants Est. completion 2019-11
    Other conditions: Psoriasis
    View official trial listing →
  • Terminated NCT NCT03913559

    Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia

    Not yet reported St. Jude Children's Research Hospital 5 participants Est. completion 2025-09-15 2 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT03964259

    Reduced IV Fluids to Improve Clearance of HDMTX in Children w/Lymphoma or Acute Lymphoblastic Leukemia

    Not yet reported Virginia Commonwealth University 10 participants Est. completion 2022-12-28 1 site
    Other conditions: Lymphoma, Acute Lymphoblastic Leukemia, Pediatric Cancer, Pediatric ALL, Pediatric Lymphoma
    View official trial listing →
  • Completed NCT NCT03965728

    Study to Investigate Safety, Tolerability, Pharmacokinetics, and Drug-drug Interaction of Multiple Oral Doses of BAY1830839 in Healthy Male Participants

    Not yet reported Bayer 67 participants Est. completion 2022-05-11 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT04022980

    Nivolumab Consolidation in Older (≥ 65) Patients With Primary CNS Lymphoma

    Not yet reported Wake Forest University Health Sciences 14 participants Est. completion 2025-12-22 4 sites
    Other conditions: Brain and Nervous System, Eye and Orbit
    View official trial listing →
  • Status unknown NCT NCT04077957

    Treat-to-target Strategy in Ankylosing Spondylitis Using Etanercept and Conventional Synthetic DMARDs

    Not yet reported Nanfang Hospital, Southern Medical University 100 participants Est. completion 2022-07-02 1 site Stand-alone
    Other conditions: Ankylosing Spondylitis, Spondyloarthritis
    View official trial listing →
  • Status unknown NCT NCT04120350

    R2-MTX With Lenalidomide Maintenance in Newly-diagnosed PCNSL：a Multicenter Phase Ib/II Stuty

    Not yet reported, Not yet reported Peking Union Medical College Hospital 47 participants Est. completion 2024-08 1 site Stand-alone
    Other conditions: Primary Central Nervous System Lymphoma
    View official trial listing →
  • Status unknown NCT NCT04129710

    A Trial to Compare Ibrutinib Versus Lenalidomide in Combination With MRE-chemotherapy for Adult Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL)

    Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 120 participants Est. completion 2025-12-31 1 site Stand-alone
    Other conditions: Recurrent/RefractoryPrimary Central Nervous System Lymphoma (PCNSL)
    View official trial listing →
  • Completed NCT NCT04170504

    Efficacy of Chinese Herbal Medicine Qing Re Huo Xue in Patients With Rheumatoid Arthritis

    Not yet reported, Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 204 participants Est. completion 2022-06-28 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT04192617

    A Study to Evaluate the Safety and Efficacy of SM03 in Patients With Rheumatoid Arthritis Receiving Methotrexate

    Not yet reported SinoMab BioScience Ltd 156 participants Est. completion 2016-02-03 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT04283955

    A Retrospective Cohort Study: The Influence of MTHFR C677T and A1298C on the High-dose Methotrexate-Related Toxicities in Pediatric Patients With Non-Hodgkin Lymphoma

    Sun Yat-sen University 93 participants Est. completion 2019-03-01 1 site
    Other conditions: Pediatric NHL
    View official trial listing →
  • Status unknown NCT NCT04308343

    The Aromatase Inhibitor and Gnrh Antagonist Versus Methotrexate for Management of Undisturbed Ectopic Pregnancy

    Not yet reported Assiut University 120 participants Est. completion 2022-09-01
    Other conditions: Ectopic Pregnancy
    View official trial listing →
  • Status unknown NCT NCT04356222

    Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

    Not yet reported Hui Bu 30 participants Est. completion 2023-06 Stand-alone
    Other conditions: Leptomeningeal Metastasis, Durvalumab
    View official trial listing →
  • Completed NCT NCT04360785

    Effect of Two Methotrexate in Sync With the First Adalimumab to Prevent the Immunisation Anti Ada in Spondyloarthritis

    Not yet reported Assistance Publique - Hôpitaux de Paris 124 participants Est. completion 2023-02-27 17 sites Stand-alone
    Other conditions: Spondyloarthritis
    View official trial listing →
  • Completed NCT NCT04383743

    Pembrolizumab and Combination Chemotherapy Before Surgery for the Treatment of Muscle-Invasive Bladder Cancer

    Not yet reported University of Washington 17 participants Est. completion 2025-03-04 1 site Stand-alone
    Other conditions: Stage II Bladder Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8, Muscle Invasive Bladder Carcinoma
    View official trial listing →
  • Completed NCT NCT04401774

    Nivolumab Maintenance in Newly Diagnosed PCNSL With Persistent CSF Circulating Tumor DNA After Completion of First-Line Chemotherapy

    Not yet reported Memorial Sloan Kettering Cancer Center 14 participants Est. completion 2026-01-22 7 sites Stand-alone
    Other conditions: Primary Central Nervous System Lymphoma (PCNSL)
    View official trial listing →
  • Completed NCT NCT04433650

    Pictorial Support in Person-centred Care for Children (PicPecc)

    Not yet reported Göteborg University 29 participants Est. completion 2025-03-31 1 site Stand-alone
    Other conditions: Childhood Cancer, Communication, Symptoms and Signs
    View official trial listing →
  • Withdrawn NCT NCT04434118

    Anti-rheumatic Drug Use and Risk of COVID-19 Infection in Rheumatoid Arthritis Patients

    Sadat City University Est. completion 2021-12-30 1 site
    Other conditions: Rheumatoid Arthritis, COVID
    View official trial listing →
  • Active, not recruiting NCT NCT04435288

    Spondyloarthritis: Inducing Drug-free Remission by Early TNF-alpha Blockade

    Not yet reported University Hospital, Ghent 90 participants Est. completion 2028-12-31 6 sites
    Other conditions: Peripheral Spondyloarthritis
    View official trial listing →
  • Status unknown NCT NCT04453345

    TPM Regimen (Thalidomide, Prednisone and Methotrexate) in LGLL

    Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 42 participants Est. completion 2025-05-20 9 sites Stand-alone
    Other conditions: T-LGL Leukemia, Clpd-Nk
    View official trial listing →
  • Status unknown NCT NCT04469829

    Methotrexate Versus Secukinumab Safety in Psoriasis Patients With Metabolic Syndrome

    Not yet reported Universita di Verona 70 participants Est. completion 2022-12-31 1 site
    Metabolic syndrome Other conditions: Psoriasis
    View official trial listing →
  • Status unknown NCT NCT04481815

    Rituximab Plus Methotrexate With or Without Lenalidomide in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

    Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 240 participants Est. completion 2025-12-30 1 site Stand-alone
    Other conditions: PCNSL
    View official trial listing →
  • Terminated NCT NCT04501614

    A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

    Not yet reported, Not yet reported Takeda 11 participants Est. completion 2024-07-19 64 sites Stand-alone
    Other conditions: Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL), Ph+ Mixed Phenotype Acute Leukemia (MPAL), Philadelphia Chromosome-Like ALL (Ph-like ALL)
    View official trial listing →
  • Active, not recruiting NCT NCT04562558

    Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia

    Not yet reported xiang yang 228 participants Est. completion 2025-12 1 site Stand-alone
    Other conditions: Gestational Trophoblastic Tumor, Gestational Trophoblastic Neoplasia, Stage I Gestational Trophoblastic Tumor, Stage II Gestational Trophoblastic Tumor, Stage III Gestational Trophoblastic Tumor, Invasive Mole, Choriocarcinoma
    View official trial listing →
  • Active, not recruiting NCT NCT04579848

    Methotrexate in Erosive Inflammatory Hand Osteoarthritis

    Not yet reported Diakonhjemmet Hospital 163 participants Est. completion 2026-12 1 site
    Osteoarthritis
    View official trial listing →
  • Status unknown NCT NCT04610476

    Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic Arthritis

    Not yet reported University of Erlangen-Nürnberg Medical School 270 participants Est. completion 2025-10-19 1 site Stand-alone
    Other conditions: Psoriatic Arthritis, Withdrawal, Reduction
    View official trial listing →
  • Status unknown NCT NCT04616872

    Treatment of Patients With Atherosclerotic Disease With Methotrexate-associated to LDL Like Nanoparticles

    Not yet reported, Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2023-10-12 2 sites Stand-alone
    Cardiovascular disease Other conditions: Atherosclerosis, Inflammation
    View official trial listing →
  • Status unknown NCT NCT04649697

    Rebamipide (Regular & Nanoparticulated) vs. Clobetasol in Management of Methotrexate-Induced Oral Ulceration in Rheumatoid Arthritis Patients

    Not yet reported Cairo University 39 participants Est. completion 2023-12-30 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT04691505

    Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Methotrexate vs Hydroxychloroquine

    Brigham and Women's Hospital 133553 participants Est. completion 2021-08-31 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT04762498

    A Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients With Uncontrolled Gout (FORWARD OL)

    Not yet reported Amgen 54 participants Est. completion 2023-12-20 12 sites Stand-alone
    Other conditions: Uncontrolled Gout, Chronic Gout
    View official trial listing →
  • Completed NCT NCT04772313

    Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapy

    Not yet reported Amgen 11 participants Est. completion 2023-04-24 15 sites Stand-alone
    Other conditions: Uncontrolled Gout
    View official trial listing →
  • Terminated NCT NCT04809623

    Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)

    Not yet reported Gilead Sciences 3 participants Est. completion 2022-10-18 5 sites Stand-alone
    Other conditions: Cutaneous Lupus Erythematosus
    View official trial listing →
  • Status unknown NCT NCT04895423

    Evaluation of the Effectiveness and Safety of Immunosuppressive and Biological Therapy of Atopic Dermatitis in Childhood

    Not yet reported National Medical Research Center for Children's Health, Russian Federation 160 participants Est. completion 2023-07-25 1 site Stand-alone
    Other conditions: Atopic Dermatitis
    View official trial listing →
  • Active, not recruiting NCT NCT04898894

    Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

    Not yet reported St. Jude Children's Research Hospital 37 participants Est. completion 2027-09 8 sites Stand-alone
    Other conditions: Acute Leukemia of Ambiguous Lineage in Relapse, Acute Myeloid Leukemia, in Relapse, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid Leukemia
    View official trial listing →
  • Status unknown NCT NCT04899453

    Intravitreal MTX and ZR Regimen in Newly Diagnosed PVRL

    Not yet reported Peking Union Medical College Hospital 42 participants Est. completion 2024-08-01 1 site Stand-alone
    Other conditions: Primary Vitreoretinal Lymphoma
    View official trial listing →
  • Completed NCT NCT04916847

    Comparative Analysis of Anti-COVID-19 (Severe Acute Respiratory Syndrome) Humoral and Memory T Cell Responses in Children With Various Degrees of Immunosuppression:

    Assistance Publique - Hôpitaux de Paris 205 participants Est. completion 2022-12-07 1 site
    Other conditions: Immune Response
    View official trial listing →
  • Status unknown NCT NCT04958538

    MTX and Steroid for III-IV aGVHD Treatment

    Not yet reported Peking University People's Hospital 30 participants Est. completion 2023-01-30 1 site Stand-alone
    Other conditions: Acute Graft Versus Host Disease
    View official trial listing →
  • Completed NCT NCT04965597

    Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

    Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2026-02-18 24 sites Stand-alone
    Other conditions: Bone Marrow Failure Syndrome, Congenital Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Hereditary Sideroblastic Anemia, Paroxysmal Nocturnal Hemoglobinuria, Shwachman-Diamond Syndrome, Hematologic Neoplasm With Germline GATA2 Mutation, Hematologic Neoplasm With Germline SAMD9 Mutation, Hematologic Neoplasm With Germline SAMD9L Mutation
    View official trial listing →
  • Status unknown NCT NCT04967950

    An Efficacy Study of Secukinumab In Enthesitis of Psoriatic Arthritis Patients

    Not yet reported Peking Union Medical College Hospital 60 participants Est. completion 2022-12-31 1 site Stand-alone
    Other conditions: Psoriatic Arthritis
    View official trial listing →
  • Status unknown NCT NCT05026229

    A Study of Dasatinib Plus Reduced Intensive Consolidation Chemotherapy in Ph+ Adult ALL

    Not yet reported First Affiliated Hospital Xi'an Jiaotong University 60 participants Est. completion 2023-06-30 1 site Stand-alone
    Other conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma, Philadelphia-Positive Acute Lymphoblastic Leukemia, ALL, Adult
    View official trial listing →
  • Status unknown NCT NCT05049473

    Treatment of Mature B-ALL and Burkitt Lymphoma (BL) in Adult Patients. BURKIMAB-14.

    Not yet reported PETHEMA Foundation 100 participants Est. completion 2024-01 29 sites Stand-alone
    Other conditions: Mature B-Cell Leukemia Burkitt Type, Burkitt Lymphoma (BL), Unclassifiable Lymphoma Between DCBL and BL
    View official trial listing →
  • Status unknown NCT NCT05057130

    Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors

    Not yet reported, Not yet reported Blokhin's Russian Cancer Research Center 50 participants Est. completion 2024-12 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Neoplasms, Connective Tissue, Neoplasms, Connective and Soft Tissue, Sarcoma, Sarcoma of Bone
    View official trial listing →
  • Completed NCT NCT05117593

    Investigate the Safety, Tolerability and Pharmacokinetics of FBL-MTX

    Not yet reported SOLFARCOS - Pharmaceutical and Cosmetic Solutions Ltd 32 participants Est. completion 2021-10-19 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Active, not recruiting NCT NCT05146739

    Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane

    Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2027-05-09 19 sites Stand-alone
    Other conditions: Acute Myeloid Leukemia Post Cytotoxic Therapy, Myelodysplastic Syndrome Post Cytotoxic Therapy, Myeloid Leukemia Associated With Down Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Mixed Phenotype Acute Leukemia, Refractory Myelodysplastic Syndrome
    View official trial listing →
  • Completed NCT NCT05149365

    Sitagliptin for Prevention of aGVHD After Alternative Donor Transplation

    Not yet reported The First Affiliated Hospital of Soochow University 190 participants Est. completion 2025-06-16 1 site
    Other conditions: Acute-graft-versus-host Disease, Allogeneic Hematopoietic Stem Cell Transplantation
    View official trial listing →
  • Active, not recruiting NCT NCT05192889

    Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax

    Not yet reported, Not yet reported St. Jude Children's Research Hospital 35 participants Est. completion 2027-02 2 sites Stand-alone
    Other conditions: Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic Leukemia
    View official trial listing →
  • Terminated NCT NCT05306353

    CD40L Antagonism in Rheumatoid Arthritis (RA)

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 2 participants Est. completion 2025-07-28 5 sites Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Active, not recruiting NCT NCT05316701

    Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

    Not yet reported Orca Biosystems, Inc. 187 participants Est. completion 2026-07 19 sites
    Other conditions: Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Mixed Phenotype Acute Leukemia, Undifferentiated Leukemia, Myelodysplastic Syndrome, Acute Leukemia, Therapy-Related Myelodysplastic Syndrome
    View official trial listing →
  • Completed NCT NCT05320159

    Treatment Effectiveness Among Psoriasis Patients Treated With Cosentyx (Secukinumab)

    Novartis Pharmaceuticals 17743 participants Est. completion 2021-03-31 1 site
    Other conditions: Psoriasis
    View official trial listing →
  • Completed NCT NCT05374785

    Efficacy and Safety Study Comparing CPL409116 to Placebo in Participants With Active Rheumatoid Arthritis

    Not yet reported Celon Pharma SA 106 participants Est. completion 2024-05-27 10 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT05380934

    A Clinical Trial of Safety and Tolerance of TQH3821 Tablets in Adult Healthy Subjects

    Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 63 participants Est. completion 2023-05-20 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT05390749

    Sequential Treatment With RO-MTX After Pomalidomide, Orelabrutinib, Rituximab (POR) in Newly-diagnosed PCNSL

    Not yet reported Peking Union Medical College Hospital 50 participants Est. completion 2026-04-01 3 sites Stand-alone
    Other conditions: Primary Central Nervous System Lymphoma
    View official trial listing →
  • Completed NCT NCT05392179

    A Study in Subjects With Retinitis Pigmentosa

    Not yet reported Aldeyra Therapeutics, Inc. 8 participants Est. completion 2023-06-23 1 site
    Obstructive sleep apnea
    View official trial listing →
  • Status unknown NCT NCT05393050

    Efficacy and Safety of Colquhounia Root Tablet in Patients With Rheumatoid Arthritis

    Not yet reported Quan Jiang 120 participants Est. completion 2024-06 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT05408208

    Intralesional Injection Of Methotrexate Versus Triamcinolone Acetonid In Treatment Of Localized Psoriasis

    Not yet reported Sohag University 30 participants Est. completion 2023-05-21 1 site
    Other conditions: Localized Psoriasis
    View official trial listing →
  • Completed NCT NCT05421299

    A Study to Assess 7/8 HLA-matched Hematopoietic Stem Cell Transplantation Participants Treated With or Without Abatacept in Combination With a Calcineurin Inhibitor and Methotrexate

    Bristol-Myers Squibb 378 participants Est. completion 2021-02-15 1 site
    Other conditions: Stem Cell Transplantation
    View official trial listing →
  • Status unknown NCT NCT05424393

    Real-World Study on Long-term Treatment With YISAIPU for Fujian RA Patients

    The First Affiliated Hospital of Xiamen University 500 participants Est. completion 2025-12-31 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT05426824

    The Whole-course Management of Pegaspargase in ENKTL

    Not yet reported The First Affiliated Hospital with Nanjing Medical University 72 participants Est. completion 2025-07-15 1 site Stand-alone
    Other conditions: Extranodal NK/T Cell Lymphoma
    View official trial listing →
  • Active, not recruiting NCT NCT05457556

    Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

    Not yet reported Children's Oncology Group 66 participants Est. completion 2027-07-07 63 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome
    View official trial listing →
  • Completed NCT NCT05489224

    A Study to Compare Efficacy and Safety of CT-P47 and RoActemra in Patients With Rheumatoid Arthritis

    Not yet reported Celltrion 471 participants Est. completion 2023-11-23 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Withdrawn NCT NCT05494593

    A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)

    Not yet reported Takeda Est. completion 2025-08-29 8 sites Stand-alone
    Other conditions: Mucopolysaccharidosis (MPS), Hunter Syndrome
    View official trial listing →
  • Completed NCT NCT05533372

    MAD Study of IA-14069

    Not yet reported ILAb Co., Ltd. 78 participants Est. completion 2025-10-15 1 site Stand-alone
    Other conditions: Healthy, Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT05576532

    Venetoclax Plus IM2 Regimen for Relapsed and Refractory T Lymphoblastic Lymphoma/Leukemia

    Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 30 participants Est. completion 2025-10-10 1 site Stand-alone
    Other conditions: T-lymphoblastic Lymphoma, Relapsed Disease, Refractory Lymphoma, Refractory Leukemia, Safety, Efficacy, Self
    View official trial listing →
  • Active, not recruiting NCT NCT05600426

    A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)

    Not yet reported Boston Children's Hospital 53 participants Est. completion 2029-12 52 sites
    Other conditions: Severe Aplastic Anemia
    View official trial listing →
  • Completed NCT NCT05602675

    A Drug Interaction Study of LY3871801 in Healthy Participants

    Not yet reported Eli Lilly and Company 39 participants Est. completion 2023-03-29 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05616871

    An Observational Study to Assess Change in Disease Activity and Treatment Patterns of Upadacitinib When Given Alone or Co-Administered With Methotrexate in Adult Participants With Active Psoriatic Arthritis

    AbbVie 464 participants Est. completion 2026-06-11 89 sites
    Other conditions: Psoriatic Arthritis
    View official trial listing →
  • Status unknown NCT NCT05623592

    Methotrexate as Remission Maintenance Therapy After Remission-Induction With Tocilizumab and Glucocorticoids in Giant Cell Arteritis

    Not yet reported University of Bonn 52 participants Est. completion 2025-11 1 site Stand-alone
    Other conditions: Giant Cell Arteritis
    View official trial listing →
  • Active, not recruiting NCT NCT05663866

    Premedication to Reduce Amivantamab Associated Infusion Related Reactions

    Not yet reported Janssen Research & Development, LLC 68 participants Est. completion 2027-03-31 36 sites Stand-alone
    Other conditions: Carcinoma, Non-Small-Cell Lung
    View official trial listing →
  • Suspended NCT NCT05691478

    A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 1122 participants Est. completion 2030-03-20 202 sites Stand-alone
    Obstructive sleep apnea
    View official trial listing →
  • Completed NCT NCT05745831

    Development and Validation of a Therapeutic Decision Aid in Ectopic Pregnancy: GEUDECID Study

    Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 109 participants Est. completion 2024-04-22 15 sites
    Other conditions: To Validate a Decision Aid for Ectopic Pregnancy
    View official trial listing →
  • Status unknown NCT NCT05875285

    Methotrexate Iontophoresis Versus Coal Tar Ointement in the Treatment of Primary Palmer Hyper Hidrosis

    Not yet reported Cairo University 60 participants Est. completion 2023-10-01 1 site Stand-alone
    Other conditions: Hyperhidrosis, Iontophore
    View official trial listing →
  • Status unknown NCT NCT05899751

    Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate

    Protherics Medicines Development Limited 1000 participants Est. completion 2024-12 5 sites
    Other conditions: Acute Kidney Injury, Drug Toxicity
    View official trial listing →
  • Status unknown NCT NCT05918718

    Assessment of the Efficacy of Letrozole in the Treatment of Ectopic Pregnancy

    Not yet reported, Not yet reported Tehran University of Medical Sciences 150 participants Est. completion 2024-12-20 1 site Stand-alone
    Other conditions: Ectopic Pregnancy
    View official trial listing →
  • Completed NCT NCT06038968

    Methotrexate Infusion and Intrasilicone Injection During Diabetic Vitrectomy

    Not yet reported Minia University 60 participants Est. completion 2024-01-01 1 site Stand-alone
    Other conditions: Diabetic Retinopathy, Vitreomacular Traction
    View official trial listing →
  • Completed NCT NCT06048224

    Phase III Clinical Trial Comparing the Safety, Efficacy, and Immunogenicity of Recombinant Anti-interleukin-6 Receptor Humanized Monoclonal Antibody Injection in Combination With Methotrexate and Jamelor ® in the Treatment of Moderate to Severe Rheumatoid Arthritis

    Not yet reported Zhejiang Hisun Pharmaceutical Co. Ltd. 669 participants Est. completion 2022-01-31 1 site
    Other conditions: Moderate to Severe Active Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT06073093

    A Study to Evaluate SAR441566 Efficacy and Safety in Adults With Rheumatoid Arthritis

    Not yet reported Sanofi 264 participants Est. completion 2025-07-02 102 sites
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT06115824

    New-diagnosed PCNSL Treated With Methotrexate (MTX) and Orelabrutinib-based Regimen

    Huashan Hospital 136 participants Est. completion 2024-07-30 1 site
    Other conditions: Primary Central Nervous System Lymphoma
    View official trial listing →
  • Status unknown NCT NCT06150794

    Methotrexate Alone vs Combination With Excimer Light in Nail Psoriasis

    Not yet reported Assiut University 20 participants Est. completion 2025-03-01 1 site
    Other conditions: Nail Psoriasis
    View official trial listing →
  • Not yet recruiting NCT NCT06154590

    Anastrozole Adjuvant Trial - Study of Anastrozole Compared to NOLVADEX (Tamoxifen Citrate) for Adjuvant Treatment of Early Breast Cancer Clinical Studies), Adjunct Cytotoxic Chemotherapy and Malignant Joint Tumor

    DR. DIANE CHISESI NFS. MD. PHD. 100 participants Est. completion 2026-09 1 site
    Other conditions: Metastatic Breast Cancer, Tumor, Muscle Neoplasms, Chronic Pain
    View official trial listing →
  • Enrolling by invitation NCT NCT06204614

    Drug Screening Using IMD in Bladder Cancer

    Not yet reported Brigham and Women's Hospital 18 participants Est. completion 2028-08-01 1 site Stand-alone
    Other conditions: Muscle Invasive Bladder Urothelial Carcinoma
    View official trial listing →
  • Completed NCT NCT06229145

    A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout

    Not yet reported Amgen 306 participants Est. completion 2026-03-26 74 sites Stand-alone
    Other conditions: Gout
    View official trial listing →
  • Enrolling by invitation NCT NCT06281184

    A 30-month Follow-up of MERINO Participants to Evaluate Long-term Effects of Methotrexate in Erosive Hand OA.

    Diakonhjemmet Hospital 108 participants Est. completion 2027-12-01 1 site
    Osteoarthritis
    View official trial listing →
  • Status unknown NCT NCT06289205

    "Comparing Methotrexate Usage Techniques to Prevent Proliferative Vitreoretinopaty After Retinal Detachment Vitrectomy"

    Not yet reported, Not yet reported University of Health Sciences Lahore 120 participants Est. completion 2025-05 1 site Stand-alone
    Other conditions: Proliferative Vitreoretinopathy
    View official trial listing →
  • Completed NCT NCT06512766

    a Retrospective Study on the Systemic Treatment of LPP and FFA

    Erasmus Medical Center 315 participants Est. completion 2023-02-01 1 site
    Other conditions: Cicatricial Alopecia, Lichen Planopilaris, Lichen Plano-Pilaris, Frontal Fibrosing Alopecia, Hair Diseases, Scarring Alopecia, Hair Loss/Baldness
    View official trial listing →
  • Status unknown NCT NCT06554470

    Local vs Systemic Methotrexate in Management of Uterine Ectopic Pregnancy

    Not yet reported Tanta University 34 participants Est. completion 2025-07-01 1 site Stand-alone
    Other conditions: Local, Systemic, Methotrexate, Uterine Ectopic Pregnancy
    View official trial listing →
  • Active, not recruiting NCT NCT06673134

    Prospective Cohort Establishment and Clinical Observation of Children With Crohn's Disease

    Tongji Hospital 100 participants Est. completion 2028-07-24 1 site
    Other conditions: Crohn Disease
    View official trial listing →
  • Not yet recruiting NCT NCT06719479

    A Clinical Trial to Evaluate Effect of IAE0972 Combined with Chemotherapy for R/M HNSCC or NPC(Note: It is Currently Phase II.).

    Not yet reported, Not yet reported SUNHO（China）BioPharmaceutical CO., Ltd. 60 participants Est. completion 2028-01-01 Stand-alone
    Other conditions: NPC, HNSCC, Recurrence, Metastasis
    View official trial listing →
  • Not yet recruiting NCT NCT06724952

    Effect of Silymarin in Rheumatoid Arthritis Patients Treated With Methotrexate

    Not yet reported Tanta University 44 participants Est. completion 2025-04-10 1 site
    Other conditions: Rheumatoid Arthritis (RA)
    View official trial listing →
  • Enrolling by invitation NCT NCT06773936

    Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

    Not yet reported SWOG Cancer Research Network 55 participants Est. completion 2033-07 11 sites
    Other conditions: Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia, CD19+ Acute Leukemia
    View official trial listing →
  • Not yet recruiting NCT NCT06877455

    Topical Methotrexate with Fractional CO2 Laser in Treatment of Non Segmental Vitiligo

    Not yet reported Assiut University 50 participants Est. completion 2026-12-30 Stand-alone
    Other conditions: Vitiligo
    View official trial listing →
  • Not yet recruiting NCT NCT06943482

    Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease

    Not yet reported National University Hospital, Singapore 40 participants Est. completion 2028-02-01 1 site Stand-alone
    Other conditions: Idiopathic Granulomatous Mastitis
    View official trial listing →
  • Not yet recruiting NCT NCT06949267

    A Study of iMSC for the Prevention of Acute Graft-versus-host Disease After Allogeneic Hematopoietic Stem Cell Transplantation

    Not yet reported Ruijin Hospital 56 participants Est. completion 2028-03-31 Stand-alone
    Other conditions: Acute Graft-versus-Host Disease
    View official trial listing →
  • Not yet recruiting NCT NCT06965244

    Lenalidomide vs Methotrexate in Difficult-to-treat Cutaneous Lupus Erythematosus

    Not yet reported Assistance Publique - Hôpitaux de Paris 122 participants Est. completion 2029-04-01
    Other conditions: Cutaneous Lupus Erythematosus (CLE)
    View official trial listing →
  • Active, not recruiting NCT NCT07008846

    Efficacy of Tofacitinib, Methotrexate Combination Therapy Versus Upadacitinib, Methotrexate Combination Therapy in Moderate to Severe Rheumatoid Arthritis

    Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 96 participants Est. completion 2026-09-30 1 site Stand-alone
    Other conditions: Moderate to Severe Rheumatoid Arthritis
    View official trial listing →
  • Not yet recruiting NCT NCT07156604

    Vebreltinib for Neoadjuvant in METex 14 Skipping Mutant Stage IIA-IIIB (N2) Non-small Cell Lung Cancer (NSCLC)

    Not yet reported Fudan University 30 participants Est. completion 2030-09-30 1 site
    Other conditions: NSCLC, Neoadjuvant Therapy
    View official trial listing →
  • Active, not recruiting NCT NCT07176390

    A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)

    Not yet reported Merck Sharp & Dohme LLC 182 participants Est. completion 2029-03-03 62 sites Stand-alone
    Other conditions: Arthritis, Rheumatoid
    View official trial listing →
  • Not yet recruiting NCT NCT07288307

    Surgical Evacuation Versus Methotrexate Injection in Treatment of Caesarean Scar Pregnancy [Clinical Trial ]

    Not yet reported Minia University 42 participants Est. completion 2027-02-01 Stand-alone
    Other conditions: Caesarean Scar Pregnancy
    View official trial listing →
  • Not yet recruiting NCT NCT07291102

    Comparison of Neurocognitive Outcome in Two Standard Regimen for Treatment of Low-risk Medulloblastoma

    Not yet reported Nationwide Children's Hospital 96 participants Est. completion 2038-10 2 sites Stand-alone
    Other conditions: Medulloblastoma
    View official trial listing →
  • Not yet recruiting NCT NCT07327476

    Effect of Oral Ice Chips to Prevent Chemotherapy-Induced Oral Mucositis in Patient With Solid Tumor Treated With 5 Fluorouracil and Methotrexate

    Not yet reported University of Health Sciences Lahore 102 participants Est. completion 2026-11-30 1 site
    Other conditions: Chemotherapy Induced Oral Mucositis
    View official trial listing →
  • Not yet recruiting NCT NCT07357649

    Baricitinib Effects on Procoagulant State in Rheumatoid Arthritis

    Not yet reported Tanta University 100 participants Est. completion 2026-12 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Not yet recruiting NCT NCT07361133

    Cyclophosphamide and Etoposide as a Metronomic Therapy in Advanced Head and Neck Squamous Cell Cancer

    Not yet reported National Cancer Institute, Egypt 120 participants Est. completion 2026-09 1 site
    Other conditions: Squamous Cell Carcinoma, Advanced Head and Neck Cancer
    View official trial listing →
  • Not yet recruiting NCT NCT07406230

    Methotrexate Early Toxicity Monitoring

    Not yet reported Assistance Publique Hopitaux De Marseille 50 participants Est. completion 2027-12 1 site Stand-alone
    Other conditions: Primary Central Nervous System Lymphoma
    View official trial listing →
  • Withdrawn NCT NCT07498465

    A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia

    Not yet reported Children's Oncology Group Est. completion 2028-11-12 Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia, Childhood Mixed Phenotype Acute Leukemia, Mixed Phenotype Acute Leukemia
    View official trial listing →
  • Not yet recruiting NCT NCT07562568

    SHR2554/AZA + Overlapped TBF for High-risk/Relapsed Leukemia/MDS

    Not yet reported The First Affiliated Hospital of Soochow University 160 participants Est. completion 2030-06 1 site Stand-alone
    Other conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, MDS, Transplantation, Stem Cell, Conditioning Therapy, SHR2554, Azacytidine
    View official trial listing →
  • Not yet recruiting NCT NCT07581418

    Comparison of Methotrexate and Tofacitinib in Chronic Plaque Psoriasis

    Not yet reported Pak Emirates Military Hospital 88 participants Est. completion 2026-12-01
    Other conditions: Chronic Plaque Psoriasis
    View official trial listing →
  • Not yet recruiting NCT NCT07636564

    Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More Treatment

    Not yet reported SWOG Cancer Research Network 90 participants Est. completion 2032-04-16 Stand-alone
    Other conditions: Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, T Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT07662265

    Tocilizumab in Refractory ASS-ILD

    Hu Yinan 111 participants Est. completion 2025-10-31 1 site
    Other conditions: Antisynthetase Syndrome, Tocilizumab
    View official trial listing →
  • Not yet recruiting NCT NCT07677813

    Orelabrutinib Combined With Induction Therapy Followed by Sequential Monotherapy Maintenance in MCD Subtype Diffuse Large B-cell Lymphoma

    Not yet reported Ou Bai, MD/PHD 66 participants Est. completion 2031-12-31 1 site Stand-alone
    Other conditions: DLBCL - Diffuse Large B Cell Lymphoma
    View official trial listing →
  • Not yet recruiting NCT NCT07758621

    SYS6010 vs Investigator's Choice of Monotherapy in Patients With Recurrent or Metastatic HNSCC

    Not yet reported CSPC Megalith Biopharmaceutical Co.,Ltd. 340 participants Est. completion 2028-12-01
    Other conditions: Head and Neck Squamous Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT07806357

    Prednisolone Monotherapy Versus Prednisolone Plus Methotrexate in ENL

    Not yet reported Chittagong Medical College 19 participants Est. completion 2019-12-31 1 site Stand-alone
    Other conditions: Leprosy
    View official trial listing →
  • Not yet recruiting NCT NCT07812493

    Pirtobrutinib Plus Methotrexate-Based Chemoimmunotherapy for Systemic DLBCL With CNS Involvement

    Not yet reported Pengpeng Xu 24 participants Est. completion 2030-09-01 1 site
    Other conditions: Pirtobrutinib, Immunochemotherapy, DLBCL - Diffuse Large B Cell Lymphoma, CNS Involvement of Systemic Lymphoma
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: Methotrexate Sodium, METHOTREXATE

Related On The Pen coverage

No related coverage yet.

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