About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Methotrexate Sodium
- Company
- Amgen
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 217 recruiting
Efficacy results: Not yet reported
217 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 7, 2026
Find a Clinical Trial Near Me
See recruiting studies for Methotrexate Sodium and check eligibility with the study team.
Trial details
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Recruiting NCT NCT00501826
Combination Chemotherapy and Nelarabine in Treating Patients With T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Not yet reported M.D. Anderson Cancer Center 160 participants Est. completion 2026-10-31 1 site Stand-aloneOther conditions: T Acute Lymphoblastic Leukemia, T Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT00920972
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
Not yet reported, Not yet reported Washington University School of Medicine 220 participants Est. completion 2031-12 28 sites Stand-aloneOther conditions: Metabolic Disorders, Hematologic, Immune, or Bone Marrow Disorders, Hemoglobinopathies, Non-malignant DisordersView official trial listing → -
Recruiting NCT NCT01371630
Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 276 participants Est. completion 2027-12-25 1 site Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, Burkitt-Like Lymphoma With 11q Aberration, High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements, High Grade B-Cell Lymphoma, Not Otherwise Specified, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Burkitt Lymphoma, Refractory B Acute Lymphoblastic Leukemia, Refractory Burkitt LymphomaView official trial listing → -
Recruiting NCT NCT01706692
Swiss Dermatology Network of Targeted Therapies (SDNTT)
Swiss Dermatology Network for Targeted Therapies 1121 participants Est. completion 2032-03-15 6 sitesOther conditions: PsoriasisView official trial listing → -
Recruiting NCT NCT01848028
PsoBest - The German Psoriasis Registry
Universitätsklinikum Hamburg-Eppendorf 3500 participants Est. completion 2032-12 1 siteOther conditions: Psoriasis, Psoriatic-arthritisView official trial listing → -
Recruiting NCT NCT02265770
An International Clinical Program for the Diagnosis and Treatment of Children With Ependymoma
Not yet reported, Not yet reported Centre Leon Berard 536 participants Est. completion 2031-08 40 sites Stand-aloneOther conditions: Childhood EpendymomaView official trial listing → -
Recruiting NCT NCT02416388
Study to Improve OS in 18 to 60 Year-old Patients, Comparing Daunorubicin Versus High Dose Idarubicin Induction Regimens, High Dose Versus Intermediate Dose Cytarabine Consolidation Regimens, and Standard Versus MMF Prophylaxis of GvHD in Allografted Patients in First CR
Not yet reported, Not yet reported University Hospital, Angers 3100 participants Est. completion 2032-01 56 sitesOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT02422641
Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis
Not yet reported Wake Forest University Health Sciences 16 participants Est. completion 2027-07 3 sites Stand-aloneOther conditions: Metastatic Breast Cancer, Leptomeningeal DiseaseView official trial listing → -
Recruiting NCT NCT02657785
Treatment of PCNSL With R-IDARAM and Intrathecal Immunochemotherapy
Not yet reported, Not yet reported Navy General Hospital, Beijing 100 participants Est. completion 2030-12 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT02714634
Clinical Trial Evaluating Methotrexate or Leflunomide + Targeted Therapy Versus Methotrexate or Leflunomide + Sulfasalazine + Hydroxychloroquine in Patients With Rheumatoid Arthritis and Insufficient Response to Methotrexate or Leflunomide
Not yet reported University Hospital, Strasbourg, France 286 participants Est. completion 2029-03 1 site Stand-aloneOther conditions: Rheumatoid Arthritis, Insufficient Response to Methotrexate or LeflunomideView official trial listing → -
Recruiting NCT NCT02836158
Therapeutic Effects of R-IDARAM and Intrathecal Immunochemotherapy on Elderly Patients With PCNSL
Not yet reported, Not yet reported Navy General Hospital, Beijing 100 participants Est. completion 2030-12 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT02877303
Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center 80 participants Est. completion 2026-11-01 1 site Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, B Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT02897700
A Randomized Trial of Chemotherapy in Surgical Patients With Infiltrating Ductal Carcinoma of Breast
Not yet reported Shanghai Jiao Tong University School of Medicine 300 participants Est. completion 2027-12 3 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Recruiting NCT NCT03150693
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
Not yet reported Alliance for Clinical Trials in Oncology 303 participants Est. completion 2027-08 460 sites Stand-aloneOther conditions: B Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT03263572
Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center 90 participants Est. completion 2027-11-30 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia, BCR-ABL1 Fusion Protein Expression, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Philadelphia Chromosome Positive, Recurrent Acute Lymphoblastic Leukemia, Refractory Acute Lymphoblastic Leukemia, t(9;22)View official trial listing → -
Recruiting NCT NCT03414502
Treatment of Rheumatoid Arthritis With DMARDs: Predictors of Response
Not yet reported University of Nebraska 400 participants Est. completion 2029-03 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT03571321
Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia
Not yet reported University of Chicago 15 participants Est. completion 2027-09-05 2 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, ALL, Childhood, ALLView official trial listing → -
Recruiting NCT NCT03593759
Cardiac Sarcoidosis Randomized Trial
Not yet reported Ottawa Heart Institute Research Corporation 160 participants Est. completion 2026-12 31 sites Stand-aloneOther conditions: Cardiac Sarcoidosis, SarcoidosisView official trial listing → -
Recruiting NCT NCT03609112
Neurocognitive Risks in Children With Solid Tumors
Gustave Roussy, Cancer Campus, Grand Paris 1000 participants Est. completion 2025-09 1 siteOther conditions: Solid Tumor in ChildrenView official trial listing → -
Recruiting NCT NCT03643276
Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017
Not yet reported Martin Schrappe 5000 participants Est. completion 2028-07-14 115 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, PediatricView official trial listing → -
Recruiting NCT NCT03703271
Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia
Not yet reported Women's Hospital School Of Medicine Zhejiang University 70 participants Est. completion 2026-12-31 1 siteOther conditions: Gestational Trophoblastic NeoplasiaView official trial listing → -
Recruiting NCT NCT03719105
Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma
Not yet reported New York Medical College 40 participants Est. completion 2028-12-31 6 sites Stand-aloneOther conditions: NK-Cell Lymphoma, NK-Cell Leukemia, Peripheral T Cell LymphomaView official trial listing → -
Recruiting NCT NCT03728478
STep-up and Step-down Therapeutic Strategies in Childhood ARthritiS
Not yet reported Istituto Giannina Gaslini 260 participants Est. completion 2025-02-28 1 site Stand-aloneOther conditions: Oligoarthritis, Juvenile, Polyarthritis, Juvenile, Rheumatoid Factor NegativeView official trial listing → -
Recruiting NCT NCT03785574
Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule
Not yet reported Women's Hospital School Of Medicine Zhejiang University 30 participants Est. completion 2030-09-01 1 site Stand-aloneOther conditions: Hydatidiform Mole, Gestational Trophoblastic NeoplasiaView official trial listing → -
Recruiting NCT NCT03818334
Post Transplant Cyclophosphamide in Matched Unrelated Donor Stem Cell Transplantation for Hematological Malignancies
Not yet reported, Not yet reported Hospital Israelita Albert Einstein 50 participants Est. completion 2026-11-01 1 siteOther conditions: Bone Marrow Transplant Complications, Graft Versus Host Disease, Infection Viral, Engraft Failure, Immunologic SuppressionView official trial listing → -
Recruiting NCT NCT03959085
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Not yet reported Children's Oncology Group 5951 participants Est. completion 2032-03-31 231 sites Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma, Central Nervous System Leukemia, Mixed Phenotype Acute Leukemia, Testicular LeukemiaView official trial listing → -
Recruiting NCT NCT03970096
Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)
Not yet reported Fred Hutchinson Cancer Center 120 participants Est. completion 2029-12-31 3 sites Stand-aloneOther conditions: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative NeoplasmView official trial listing → -
Recruiting NCT NCT04006561
Prospective Neurobehavioral Functions in Newly-diagnosed Patients With Primary CNS Lymphoma Treated With Hyperfractionated Conformal Whole-brain Radiation Therapy Plus Simultaneous Integrated Boost
Chang Gung Memorial Hospital 36 participants Est. completion 2029-02-18 1 siteOther conditions: Primary CNS Lymphoma, Brain LymphomaView official trial listing → -
Recruiting NCT NCT04043494
International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma
Not yet reported University Hospital Muenster 683 participants Est. completion 2030-04-22 228 sites Stand-aloneOther conditions: Lymphoblastic Lymphoma, ChildhoodView official trial listing → -
Recruiting NCT NCT04179929
Treatment of Breakpoint Cluster Region-Abelson (BCR-ABL) Negative ALL in Adults
Not yet reported PETHEMA Foundation 300 participants Est. completion 2027-02 108 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT04216524
Venetoclax, SL-401, and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm
Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Blastic Plasmacytoid Dendritic Cell NeoplasmView official trial listing → -
Recruiting NCT NCT04293562
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
Not yet reported Children's Oncology Group 1400 participants Est. completion 2029-06-30 206 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT04314219
Comparing Post-Transplant Cyclophosphamide As GVHD Prophylaxis to Standard of Care for Acute Leukemia Patients
Not yet reported King Faisal Specialist Hospital & Research Center 264 participants Est. completion 2026-12 1 siteOther conditions: Acute Lymphoblastic Leukemia (ALL) in Complete Remission, Acute Myeloid Leukemia (AML) in RemissionView official trial listing → -
Recruiting NCT NCT04380740
Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis
Not yet reported Boston Children's Hospital 160 participants Est. completion 2028-06 15 sites Stand-aloneOther conditions: Graft Vs Host DiseaseView official trial listing → -
Recruiting NCT NCT04440267
Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 50 participants Est. completion 2027-12-20 1 site Stand-aloneOther conditions: Acute Leukemia of Ambiguous LineageView official trial listing → -
Recruiting NCT NCT04537689
Outcomes With Treatment and Withdraw of Ixekizumab in Patients With Plaque Psoriasis
Not yet reported Singapore General Hospital 40 participants Est. completion 2027-12-31 1 siteOther conditions: Plaque PsoriasisView official trial listing → -
Recruiting NCT NCT04540432
Evolution of Intestinal Microbiota in Patients With Juvenile Spondylarthropathy According to Typology of Treatment
Not yet reported Centre Hospitalier Universitaire de Nīmes 25 participants Est. completion 2029-06-28 4 sites Stand-aloneOther conditions: SpondylarthropathiesView official trial listing → -
Recruiting NCT NCT04546399
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Not yet reported National Cancer Institute (NCI) 461 participants Est. completion 2028-06-30 227 sites Stand-aloneOther conditions: Down Syndrome, Recurrent B Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT04628767
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 131 participants Est. completion 2027-09-30 257 sites Stand-aloneOther conditions: Renal Pelvis and Ureter Urothelial CarcinomaView official trial listing → -
Recruiting NCT NCT04656431
Feasibility of Acquiring Hyperpolarized Imaging in Patients With Primary CNS Lymphoma
Not yet reported James Rubenstein 26 participants Est. completion 2027-03-31 1 site Stand-aloneOther conditions: Primary CNS LymphomaView official trial listing → -
Recruiting NCT NCT04725422
CHronic Nonbacterial Osteomyelitis International Registry
Seattle Children's Hospital 2000 participants Est. completion 2050-08 1 siteOther conditions: Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal OsteomyelitisView official trial listing → -
Recruiting NCT NCT04737889
Rituximab, Lenalidomide Combined With Methotrexate and Temozolomide For Primary Central Nervous System Lymphoma
Not yet reported Henan Cancer Hospital 30 participants Est. completion 2026-01-13 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT04747912
Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)
Not yet reported University of Chicago 25 participants Est. completion 2028-03-01 1 site Stand-aloneOther conditions: Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia, ph+ Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT04871191
Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis
Not yet reported Assistance Publique - Hôpitaux de Paris 42 participants Est. completion 2029-03 1 siteOther conditions: Granulomatosis With Polyangiitis, Anti-neutrophil Cytoplasmic Antibody-associated VasculitisView official trial listing → -
Recruiting NCT NCT04972760
Baricitinib in Patients With Relapsing or naïve Dermatomyositis
Not yet reported Assistance Publique - Hôpitaux de Paris 62 participants Est. completion 2028-02-28 1 site Stand-aloneOther conditions: DermatomyositisView official trial listing → -
Recruiting NCT NCT05040464
Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial
Not yet reported Centre Hospitalier Universitaire, Amiens 166 participants Est. completion 2027-05 1 siteOther conditions: Crohn Disease, Azathioprine, MethotrexateView official trial listing → -
Recruiting NCT NCT05043870
Combined Immunosuppression for Pediatric Crohn's Disease
Not yet reported Children's Hospital of Fudan University 128 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Crohn Disease, Infliximab, Immunosuppression, Children, OnlyView official trial listing → -
Recruiting NCT NCT05102448
Comparison of Tofacitinib and Methotrexate in Takayasu's Arteritis
Not yet reported Shanghai Zhongshan Hospital 76 participants Est. completion 2025-12-31 1 siteOther conditions: Takayasu ArteritisView official trial listing → -
Recruiting NCT NCT05139095
Camrelizumab Plus Apatinib in Patients With High-risk Gestational Trophoblastic Neoplasia
Not yet reported Peking Union Medical College Hospital 70 participants Est. completion 2027-01-01 1 site Stand-aloneOther conditions: Gestational Trophoblastic NeoplasiaView official trial listing → -
Recruiting NCT NCT05253495
Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma
Not yet reported New York Medical College 80 participants Est. completion 2028-06-30 3 sites Stand-aloneOther conditions: Non-hodgkin Lymphoma, Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT05257018
R-CDOP Combined With Intrathecal Methotrexate for DLBCL Patients With High-risk of CNS Relapse
Not yet reported Fudan University 83 participants Est. completion 2028-12-30 2 sitesOther conditions: Diffuse Large B-cell LymphomaView official trial listing → -
Recruiting NCT NCT05260619
Lenalidomide Maintenance Treatment in Patients With Primary Central Nervous System Lymphoma
Not yet reported Seoul National University Bundang Hospital 28 participants Est. completion 2028-04-01 1 site Stand-aloneOther conditions: Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT05289687
Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL
Not yet reported Eastern Cooperative Oncology Group 20 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: T-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT05292664
Venetoclax Basket Trial for High Risk Hematologic Malignancies
Not yet reported Andrew E. Place, MD 30 participants Est. completion 2030-07-02 5 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, de Novo, Myelodysplastic Syndromes, Secondary, Myelodysplastic Syndromes, Previously Treated, Treatment-Related Acute Myeloid Leukemia, Therapy-Related Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia With Failed Remission, Lymphoblastic Lymphoma, in Relapse, Lymphoblastic Lymphoma, Refractory, Acute Leukemia of Ambiguous Lineage in Relapse, Acute Leukemia of Ambiguous LineageView official trial listing → -
Recruiting NCT NCT05427136
Early Pulmonary Dysfunction in Childhood Cancer Patients
University Children's Hospital Basel 140 participants Est. completion 2051-06 5 sitesOther conditions: Pulmonary DysfunctionView official trial listing → -
Recruiting NCT NCT05428488
Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis
Not yet reported University Hospital, Montpellier 220 participants Est. completion 2027-11 17 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT05476770
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 54 participants Est. completion 2027-11-11 31 sites Stand-aloneOther conditions: Hematologic Malignancy, AML, ALL, BPDCN, MDS, Lymphoblastic Lymphoma, Lymphoma, B-Cell, Lymphoma, T-Cell, Hodgkin Lymphoma, Mixed Phenotype Acute Leukemia, Acute Undifferentiated LeukemiaView official trial listing → -
Recruiting NCT NCT05503875
Immunoclassification of Psoriasis: a Strategy for Precision Medicine
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 100 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Immunoclassification, PsoriasisView official trial listing → -
Recruiting NCT NCT05518383
B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021
Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 300 participants Est. completion 2027-05-16 1 site Stand-aloneOther conditions: Non-hodgkin Lymphoma,B Cell, Burkitt Lymphoma, Primary Mediastinal Lymphoma, Primary CNS Lymphoma, Diffuse Large B-cell LymphomaView official trial listing → -
Recruiting NCT NCT05519579
Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia
Not yet reported Northside Hospital, Inc. 20 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT05535166
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
Not yet reported St. Jude Children's Research Hospital 130 participants Est. completion 2035-07 10 sites Stand-aloneOther conditions: MedulloblastomaView official trial listing → -
Recruiting NCT NCT05540938
Post-marketing Re-evaluation of WangBi Granules for Rheumatoid Arthritis
Not yet reported China-Japan Friendship Hospital 340 participants Est. completion 2026-03-31 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT05581030
CalPeg for Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 7 participants Est. completion 2026-10 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT05583071
Methotrexate, Tafasitamab, Lenalidomide and Rituximab in Patients With PCNSL
Not yet reported University of Cologne 20 participants Est. completion 2027-04 6 sites Stand-aloneOther conditions: Non-Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT05600660
Orelabrutinib,Rituximab and Methotrexate in Newly Diagnosed Primary Central Nervous System Lymphoma
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 28 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT05626348
The Clinical Efficacy of Immunomodulators in RA Patients
Not yet reported Qilu Hospital of Shandong University 400 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Recruiting NCT NCT05645718
Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia
Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Recruiting NCT NCT05658640
HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies
Not yet reported, Not yet reported Princess Maxima Center for Pediatric Oncology 26 participants Est. completion 2029-04-01 36 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) RefractoryView official trial listing → -
Recruiting NCT NCT05660473
Pediatric-inspired Regimen Combined With Venetoclax for Adolescent and Adult Patients With de Novo Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 100 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Precursor Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Recruiting NCT NCT05674695
Spanish Academy of Dermatology and Venereology Registry of Atopic Dermatitis Therapy
Fundación Academia Española de Dermatología 2500 participants Est. completion 2029-01-01 9 sitesOther conditions: Dermatitis, AtopicView official trial listing → -
Recruiting NCT NCT05681260
Capizzi Escalating Methotrexate Versus High Dose Methotrexate in Children With Newly Diagnosed T-cell Lymphoblastic Lymphoma (T-LBL)
Not yet reported Children's Cancer Group, China 200 participants Est. completion 2029-12-31 2 sites Stand-aloneOther conditions: T-cell Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT05698147
Selinexor in Combination With MTX+Ritu to Treat R/R CNSL
Not yet reported, Not yet reported Tong Chen, MD 30 participants Est. completion 2026-12-31 5 sites Stand-aloneOther conditions: Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT05725200
Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer
Not yet reported Oslo University Hospital 40 participants Est. completion 2040-12-31 1 site Stand-aloneOther conditions: Metastatic Colorectal CancerView official trial listing → -
Recruiting NCT NCT05745714
HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Not yet reported, Not yet reported Princess Maxima Center for Pediatric Oncology 26 participants Est. completion 2032-02-02 33 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) RefractoryView official trial listing → -
Recruiting NCT NCT05751044
HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Not yet reported, Not yet reported Princess Maxima Center for Pediatric Oncology 26 participants Est. completion 2032-02-01 33 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) RefractoryView official trial listing → -
Recruiting NCT NCT05751512
A Study to Evaluate MRG003 vs Cetuximab/Methotrexate in in the Treatment of Patients With RM-SCCHN
Not yet reported Lepu Biopharma Co., Ltd. 180 participants Est. completion 2027-12 1 siteOther conditions: Squamous Cell Carcinoma of the Head and NeckView official trial listing → -
Recruiting NCT NCT05756179
Effect of Diosmin and Hesperidin in Treatment of Patients With Rheumatoid Arthritis
Not yet reported Alexandria University 80 participants Est. completion 2026-09 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT05790330
Mind and Skin - the Neurocutaneous Axis in Atopic Eczema
King's College London 90 participants Est. completion 2027-06-01 1 siteOther conditions: Atopic DermatitisView official trial listing → -
Recruiting NCT NCT05827549
Evaluation of Treatment Efficacy According to Risk Group in Relapsed Childhood Acute Lymphoblastic Leukemia
Not yet reported Ho Joon Im 90 participants Est. completion 2032-12-31 10 sites Stand-aloneOther conditions: Acute Lymphoid LeukemiaView official trial listing → -
Recruiting NCT NCT05848687
TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II
Not yet reported, Not yet reported Tanja Andrea Gruber 90 participants Est. completion 2033-12 24 sites Stand-aloneOther conditions: Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT05921305
Mini-dose MTX Plus Standard-dose Steroid for the Initial Treatment of Acute GVHD
Not yet reported Peking University People's Hospital 218 participants Est. completion 2026-09-30 2 sitesOther conditions: Acute Graft Versus Host DiseaseView official trial listing → -
Recruiting NCT NCT05959720
Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil
Instituto do Cancer do Estado de São Paulo 180 participants Est. completion 2030-06 1 siteOther conditions: Acute Lymphoid Leukemia, Minimal Residual Disease, Gene Abnormality, Chemotherapeutic ToxicityView official trial listing → -
Recruiting NCT NCT05998642
Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary CNS Lymphoma
Not yet reported Canadian Cancer Trials Group 30 participants Est. completion 2028-12-31 8 sites Stand-aloneOther conditions: Non-hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT05998759
Telitacicept for the Treatment of Connective Tissue Disease-associated Thrombocytopenia
Not yet reported Beijing Hospital 296 participants Est. completion 2025-12 23 sites Stand-aloneOther conditions: Connective Tissue Diseases, ThrombocytopeniaView official trial listing → -
Recruiting NCT NCT06034561
Bortezomib-based Regimen for Refractory or Relapsed Acute Lymphoblastic Leukemia
Not yet reported Instituto do Cancer do Estado de São Paulo 50 participants Est. completion 2029-08 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia With Failed RemissionView official trial listing → -
Recruiting NCT NCT06037811
Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis
Not yet reported Tom Appleton 30 participants Est. completion 2028-12 1 siteOther conditions: Inflammatory Arthritis, Immune-related Adverse EventView official trial listing → -
Recruiting NCT NCT06059989
InDuctIon TREatment with SubCuTaneous Infliximab for Crohn's Disease
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 158 participants Est. completion 2025-12 1 siteOther conditions: Inflammatory Disease, Disease Crohn, Bowel DiseaseView official trial listing → -
Recruiting NCT NCT06081400
Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting
Not yet reported University Hospital, Strasbourg, France 150 participants Est. completion 2029-06 13 sitesOther conditions: Desmoid TumorView official trial listing → -
Recruiting NCT NCT06085742
BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer
Not yet reported University of Illinois at Chicago 25 participants Est. completion 2034-09 1 siteOther conditions: Breast CancerView official trial listing → -
Recruiting NCT NCT06089590
Ibd CAncer and seRious Infections in France (I-CARE 2)
Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives 6000 participants Est. completion 2031-03-01 2 sitesOther conditions: IBD, Ulcerative Colitis, Crohn DiseaseView official trial listing → -
Recruiting NCT NCT06099366
Treatment of Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia in Children
Not yet reported Hee Young Ju 116 participants Est. completion 2033-12-31 13 sites Stand-aloneOther conditions: Lymphoblastic Leukemia in ChildrenView official trial listing → -
Recruiting NCT NCT06124157
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
Not yet reported National Cancer Institute (NCI) 222 participants Est. completion 2030-12-01 159 sites Stand-aloneOther conditions: B Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06128070
Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome
Not yet reported City of Hope Medical Center 40 participants Est. completion 2030-11-22 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT06136767
Registry for Systemic Eczema Treatments
Johns Hopkins University 400 participants Est. completion 2030-12-31 1 siteOther conditions: Atopic DermatitisView official trial listing → -
Recruiting NCT NCT06177067
Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 24 participants Est. completion 2027-04 10 sites Stand-aloneOther conditions: Refractory Acute Myeloid Leukemia, Relapsed Acute Myeloid Leukemia, Acute Leukemia of Ambiguous LineageView official trial listing → -
Recruiting NCT NCT06193759
Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)
Not yet reported Children's National Research Institute 12 participants Est. completion 2032-12-29 1 site Stand-aloneOther conditions: Medulloblastoma, Childhood, Atypical Teratoid/Rhabdoid Tumor of CNS, Embryonal Tumor With Multilayered Rosettes, Pineoblastoma, Embryonal Brain Tumor Not Otherwise Specified, EpendymomaView official trial listing → -
Recruiting NCT NCT06199557
A Study to Investigate Treatment of HU and VPA, or 6-MP and VPA in Unfit AML/HR-MDS Patients
Not yet reported, Not yet reported Haukeland University Hospital 48 participants Est. completion 2029-09-30 1 siteOther conditions: Acute Myeloid Leukemia, Adult, Myelodysplastic Syndromes, AdultView official trial listing → -
Recruiting NCT NCT06207123
A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)
Not yet reported, Not yet reported University of Chicago 15 participants Est. completion 2026-12-01 2 sites Stand-aloneOther conditions: Acute Leukemia, Lymphoblastic Leukemia, Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT06239311
Efficacy and Safety of Methotrexate Versus Placebo in Adults With Atopic Dermatitis.
Not yet reported medac GmbH 277 participants Est. completion 2027-04 30 sitesOther conditions: Moderate to Severe Atopic DermatitisView official trial listing → -
Recruiting NCT NCT06247787
A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy
Not yet reported Children's Oncology Group 36 participants Est. completion 2028-03-31 19 sites Stand-aloneOther conditions: Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Myelodysplastic Syndrome, Recurrent Juvenile Myelomonocytic Leukemia, Refractory Childhood Acute Myeloid Leukemia, Refractory Childhood Myelodysplastic Syndrome, Refractory Juvenile Myelomonocytic LeukemiaView official trial listing → -
Recruiting NCT NCT06252870
Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation
Not yet reported Nantes University Hospital 82 participants Est. completion 2028-07-18 3 sites Stand-aloneOther conditions: Graft Versus Host Disease, Hematologic MalignancyView official trial listing → -
Recruiting NCT NCT06262438
CHIP-AML22/Quizartinib: Quizartinib + Chemotherapy in Newly Diagnosed Pediatric FLT3-ITD+ and NPM1wt AML Patients
Not yet reported Princess Maxima Center for Pediatric Oncology 60 participants Est. completion 2032-06 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia in ChildrenView official trial listing → -
Recruiting NCT NCT06265584
Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant
Not yet reported University of Alabama at Birmingham 56 participants Est. completion 2028-11 1 site Stand-aloneOther conditions: Acute Leukemia, Myelodysplastic Syndrome, Myeloproliferative DisordersView official trial listing → -
Recruiting NCT NCT06269536
Stress-reducing Intervention in Urothelial Carcinoma
Not yet reported Comenius University 50 participants Est. completion 2029-02-15 1 siteOther conditions: Bladder CancerView official trial listing → -
Recruiting NCT NCT06289673
Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma
Not yet reported St. Jude Children's Research Hospital 850 participants Est. completion 2039-05 5 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Mixed Phenotype Acute LeukemiaView official trial listing → -
Recruiting NCT NCT06297096
Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease
Not yet reported National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland 86 participants Est. completion 2028-03-30 1 site Stand-aloneOther conditions: Systemic Sclerosis, Interstitial Lung DiseaseView official trial listing → -
Recruiting NCT NCT06298071
A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.
Not yet reported Shanghai Institute Of Biological Products 36 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: GoutView official trial listing → -
Recruiting NCT NCT06301373
Methotrexate Combined With Tofacitinib in Rheumatoid Arthritis
Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 130 participants Est. completion 2029-12-31 5 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT06302465
Narlumosbartmab Combined With Neoadjuvant Chemotherapy in Bone-derived Malignancies With Osteolytic Lesions and Multinucleated Giant Cells
Not yet reported Peking University People's Hospital 60 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Malignant Bone TumorView official trial listing → -
Recruiting NCT NCT06315309
Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant
Not yet reported University of Alabama at Birmingham 29 participants Est. completion 2027-05 1 site Stand-aloneOther conditions: GVHD,Acute, Acute Leukemia, Myelodysplastic Syndromes, Myeloproliferative DisordersView official trial listing → -
Recruiting NCT NCT06317662
Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia
Not yet reported National Cancer Institute (NCI) 153 participants Est. completion 2028-12-31 116 sites Stand-aloneOther conditions: Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06333899
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Not yet reported Nationwide Children's Hospital 15 participants Est. completion 2035-06-01 18 sites Stand-aloneOther conditions: High Grade Glioma, Diffuse Intrinsic Pontine Glioma, Anaplastic Astrocytoma, Infant Type Hemispheric Glioma, Glioblastoma, Glioblastoma Multiforme, WHO Grade III Glioma, WHO Grade IV Glioma, Diffuse Midline Glioma, H3K27-alteredView official trial listing → -
Recruiting NCT NCT06336395
Ma-Spore ALL 2020 Study
Not yet reported National University Hospital, Singapore 500 participants Est. completion 2030-03 3 sites Stand-aloneOther conditions: B Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06354439
Use of Letrozole for Ectopic Pregnancy
Not yet reported Hospital de Clinicas de Porto Alegre 130 participants Est. completion 2026-12-31 1 siteOther conditions: Ectopic PregnancyView official trial listing → -
Recruiting NCT NCT06373055
Prediction of Therapeutic Response to Neoadjuvant Chemotherapy in Muscle Invasive Bladder Cancer Patients Using Spatial Transcriptomics
Yonsei University 250 participants Est. completion 2033-11 1 siteOther conditions: Muscle-invasive Bladder CancerView official trial listing → -
Recruiting NCT NCT06387121
Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Adult Ph- B-ALL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 53 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Precursor Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Recruiting NCT NCT06390319
Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)
Not yet reported St. Jude Children's Research Hospital 100 participants Est. completion 2033-12 4 sites Stand-aloneOther conditions: T-cell Acute Lymphoblastic Leukemia, T-cell Lymphoma, Mixed Phenotype Acute LeukemiaView official trial listing → -
Recruiting NCT NCT06475235
Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL
Not yet reported Dana-Farber Cancer Institute 15 participants Est. completion 2027-06-30 2 sites Stand-aloneOther conditions: Lymphoma, Primary Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT06498089
A Randomized, Controlled, Open-label, Multicenter Clinical Trial Comparing the Efficacy and Safety of a Precision Treatment Regimen Based on Clinical-molecular Phenotypes with a Conventional Treatment Regimen in the Treatment of Patients with Active Takayasu's Arteritis
Not yet reported Shanghai Zhongshan Hospital 124 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Takayasu ArteritisView official trial listing → -
Recruiting NCT NCT06516679
Efficacy of Risk-Stratified Treatment in Newly Diagnosed Infant Leukemia
Not yet reported Yonsei University 40 participants Est. completion 2032-12-31 10 sites Stand-aloneOther conditions: Leukemia, LymphoidView official trial listing → -
Recruiting NCT NCT06520163
Comparison Study of EAP and Disease-Specific Chemotherapy Regimens in Hematopoietic Stem Cell Mobilization for Lymphoma
Not yet reported The Affiliated People's Hospital of Ningbo University 99 participants Est. completion 2026-08 17 sitesOther conditions: Non-Hodgkin's Lymphoma, Hematopoietic Stem Cell MobilizationView official trial listing → -
Recruiting NCT NCT06528431
Design and Evaluation of an Individualized Biodrug Tapering Strategy Based on Biodrug Dosage: the MONITORA Study
Not yet reported Centre Hospitalier Universitaire de Saint Etienne 180 participants Est. completion 2027-12-19 8 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Recruiting NCT NCT06530576
Thalidomide for the Symptomatic Large Granular Lymphocytic Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 48 participants Est. completion 2027-07-01 1 site Stand-aloneOther conditions: T-LGL Leukemia, NK-LGL LeukemiaView official trial listing → -
Recruiting NCT NCT06533748
Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma
Not yet reported St. Jude Children's Research Hospital 128 participants Est. completion 2034-05 3 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT06541249
MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial
Not yet reported Icahn School of Medicine at Mount Sinai 54 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Polycythemia Vera (PV), Essential Thrombocythemia (ET), Myelofibrosis (MF)View official trial listing → -
Recruiting NCT NCT06541574
Prevention of ProliFerative Vitreoretinopathy with Intravitreal MethotreXate in Primary Retinal DEtachment Repair (FIXER) Trial
Not yet reported Cincinnati Eye Institute, Southwest Ohio 860 participants Est. completion 2026-06 1 site Stand-aloneOther conditions: Proliferative Vitreoretinopathy, Rhegmatogenous Retinal DetachmentView official trial listing → -
Recruiting NCT NCT06543992
Efficacy and Safety of Intrathecal Administration of Thiotepa in Combination With Methotrexate in Breast Cancer With Leptomeningeal Metastasis
Not yet reported The First Affiliated Hospital with Nanjing Medical University 22 participants Est. completion 2026-12-13 1 site Stand-aloneOther conditions: Leptomeningeal Metastasis of Breast CancerView official trial listing → -
Recruiting NCT NCT06554561
A Study of Pomadomide in Combination With Rituximab and Methotrexate for Newly-diagnosed Primary Central Nervous System Lymphoma
Not yet reported, Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 43 participants Est. completion 2029-08-31 1 site Stand-aloneOther conditions: PCNSLView official trial listing → -
Recruiting NCT NCT06554626
Blinatumomab Plus Venetoclax Sequenced With Inotuzumab Ozogamicin in Treating B-ALL
Not yet reported First Affiliated Hospital of Zhejiang University 20 participants Est. completion 2027-08-01 1 site Stand-aloneOther conditions: Precursor B-Cell Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06615050
A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)
Not yet reported Incyte Corporation 572 participants Est. completion 2031-01-17 30 sites Stand-aloneOther conditions: Graft-versus-host Disease (GVHD)View official trial listing → -
Recruiting NCT NCT06649136
MethMax Trial: MAXimising the METHotrexate Therapy Potential in Patients with Active Rheumatoid Arthritis
Not yet reported Medical University of Vienna 182 participants Est. completion 2026-09-30 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT06650553
Umbilical Cord Blood-Supported Haplo-HSCT for Aplastic Anemia Treatment Study
Not yet reported Shanxi Bethune Hospital 110 participants Est. completion 2027-07 1 site Stand-aloneOther conditions: Aplastic AnemiasView official trial listing → -
Recruiting NCT NCT06653634
Optimizing Treatment for Patients With Juvenile Idiopathic Arthritis in Sustained Remission: The MOVE-JIA Trial
Not yet reported Oslo University Hospital 150 participants Est. completion 2029-12 7 sites Stand-aloneOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Recruiting NCT NCT06671054
A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis
Not yet reported SynAct Pharma Aps 240 participants Est. completion 2025-12 11 sites Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Recruiting NCT NCT06674382
Haplo-HSCT for Myelofibrosis
Not yet reported Peking University People's Hospital 39 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: MyelofibrosisView official trial listing → -
Recruiting NCT NCT06682169
Evaluation of Rovadicitinib Compared to the Protocol Selected by Researchers in Third Line and Subsequent Studies of Moderate to Severe Chronic Graft-versus-host Disease
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 182 participants Est. completion 2030-12 41 sitesOther conditions: Graft-versus-host DiseaseView official trial listing → -
Recruiting NCT NCT06730542
Zanubrutinib in Combination With Pola-R-CHP and High-dose Methotrexate in Patients With Secondary CNS Lymphoma
Not yet reported Juan P. Alderuccio, MD 20 participants Est. completion 2030-04-30 1 site Stand-aloneOther conditions: CNS LymphomaView official trial listing → -
Recruiting NCT NCT06753565
L-carnitine Supplementation in Rheumatoid Arthritis Patients
Not yet reported German University in Cairo 60 participants Est. completion 2025-06 1 site Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Recruiting NCT NCT06764238
Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 1800 participants Est. completion 2031-06 27 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia ALL, Childhood Leukemia, Acute Lymphoblastic, B Cell Acute Lymphoblastic Leukemia (B-ALL)View official trial listing → -
Recruiting NCT NCT06816134
Study on the Efficacy and Safety of the TmBU Conditioning Regimen in High-risk or Relapsed/Refractory Acute Leukemia
Not yet reported The First Affiliated Hospital of Soochow University 48 participants Est. completion 2030-01-30 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Transplantation, Stem Cell, Conditioning TherapyView official trial listing → -
Recruiting NCT NCT06830421
Adjusted High-dose Chemotherapy With Autologous Stem Cell Transplant vs. Conventional Immunochemotherapy in Elderly PCNSL Patients
Not yet reported University Hospital Freiburg 340 participants Est. completion 2031-08-31 35 sites Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT06855810
Newly-diagnosed Pediatric T-cell ALL Protocol
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 610 participants Est. completion 2031-06 27 sitesOther conditions: Acute Lymphoblastic Leukemia, Childhood Leukemia, Acute Lymphoblastic, T Cell Acute Lymphoblastic Leukemia/Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT06869265
Thiotepa Combined With Busulfan and Fludarabine Conditioning Regimen for Haploidentical Hematopoietic Stem Cell Transplantation in Elderly Patients With High-Risk Acute Myeloid Leukemia
Not yet reported Peking University People's Hospital 56 participants Est. completion 2029-04-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), High Risk Acute Myeloid Leukemia(AML), Relapsed/Refractory Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT06895473
Intrathecal Cytarabine, Methotrexate, and Hydrocortisone for the Prevention of High-Grade Chimeric Antigen Receptor T-Cell-Associated Neurotoxicity Syndrome
Not yet reported OHSU Knight Cancer Institute 26 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Hematopoietic and Lymphatic System NeoplasmView official trial listing → -
Recruiting NCT NCT06913907
Changes in MTX-PG Concentrations During Subcutaneous MTX Therapy in Patients With Rheumatoid Arthritis(COSMOS Study)
Not yet reported Keio University 100 participants Est. completion 2027-12-31 1 siteOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Recruiting NCT NCT06918431
Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Not yet reported City of Hope Medical Center 53 participants Est. completion 2029-03-30 8 sites Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT06936215
Safety and Efficacy of Baricitinib on Skin Tightening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 24 participants Est. completion 2025-05 1 siteOther conditions: Diffuse Cutaneous Systemic SclerosisView official trial listing → -
Recruiting NCT NCT06941376
Pragmatic, Open-Label Study to Pilot Evaluation for Clinical Trials in Relapsing Polychondritis
Not yet reported University of Pennsylvania 20 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Relapsing PolychondritisView official trial listing → -
Recruiting NCT NCT06949982
Efficacy And Safety Of Hydroxychloroquine Combined With Methotrexate, Capecitabine And Bevacizumab Vs. Regorafenib In Participants With Refractory Metastatic Colorectal Cancer With Mutations In RAS Genes
Not yet reported Sergey Orlov, MD 60 participants Est. completion 2027-10 1 site Stand-aloneOther conditions: Metastatic Colorectal Cancer (mCRC), Colorectal NeoplasmsView official trial listing → -
Recruiting NCT NCT06960577
Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)
Not yet reported AstraZeneca 150 participants Est. completion 2028-10-31 59 sites Stand-aloneOther conditions: Urinary Bladder Neoplasms, Immune Checkpoint Inhibitors, Methotrexate, Vinblastine, Doxorubicin, Cisplatin, GemcitabineView official trial listing → -
Recruiting NCT NCT06973811
ZR-MTX for PIOL Phase II Trial
Not yet reported Peking Union Medical College Hospital 47 participants Est. completion 2029-10-30 1 site Stand-aloneOther conditions: Primary Intraocular LymphomaView official trial listing → -
Recruiting NCT NCT06985485
Full-Course Immunotherapy Consolidation for Unfit or Fit B-ALL Who Decline Chemotherapy
Not yet reported The First Affiliated Hospital of Soochow University 26 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Immunotherapy, Blinatumomab, Inotuzumab OzogamicinView official trial listing → -
Recruiting NCT NCT06997068
Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population
Not yet reported Mayo Clinic 25 participants Est. completion 2029-08-05 1 site Stand-aloneOther conditions: Metastatic Oral Cavity Carcinoma, Recurrent Oral Cavity Carcinoma, Stage IVC Lip and Oral Cavity Cancer AJCC v8, Head and Neck Cancer, Hypopharynx Cancer, Oropharynx Cancer, Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Metastatic Hypopharyngeal Carcinoma, Metastatic Laryngeal Carcinoma, Metastatic Malignant Head and Neck Neoplasm, Metastatic Oropharyngeal Carcinoma, Recurrent Hypopharyngeal Carcinoma, Recurrent Laryngeal Carcinoma, Recurrent Malignant Head and Neck Neoplasm, Recurrent Oropharyngeal Carcinoma, Stage IVC Hypopharyngeal Carcinoma AJCC v8, Stage IVC Laryngeal Cancer AJCC v8, Stage IVC Oropharyngeal (p16-Negative) Carcinoma AJCC v8View official trial listing → -
Recruiting NCT NCT07002099
Selinexor, High-dose Methotrexate, and Rituximab Combined With Radiotherapy for Newly Diagnosed, Transplant-ineligible Patients With Central Nervous System Lymphoma: An Open-label, Single-arm, Multicenter Phase II Study
Not yet reported Second Affiliated Hospital of Soochow University 26 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: LymphomasView official trial listing → -
Recruiting NCT NCT07015242
A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 65 participants Est. completion 2028-12-10 40 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Recruiting NCT NCT07021495
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
Leiden University Medical Center 840 participants Est. completion 2029-12-31 8 sitesOther conditions: Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS), Psoriasis (PsO), Atopic Dermatitis (AD), CTCL/ Mycosis FungoidesView official trial listing → -
Recruiting NCT NCT07059156
Multicenter Study of Combined Chemotherapy and Transplantation for Adult ALL
Not yet reported, Not yet reported Shanxi Bethune Hospital 50 participants Est. completion 2027-07 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, AdultView official trial listing → -
Recruiting NCT NCT07059975
UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML
Not yet reported Baylor College of Medicine 36 participants Est. completion 2031-08 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Pediatric AMLView official trial listing → -
Recruiting NCT NCT07077486
Effects of Telitacicept vs Cyclophosphamide on Lupus Related Interstitial Lung Disease
Not yet reported Tongji Hospital 100 participants Est. completion 2027-03-25 1 site Stand-aloneOther conditions: Lupus or SLE, Interstitial Lung Disease, Systemic Lupus ErythematosusView official trial listing → -
Recruiting NCT NCT07086924
Genetic Variation in TRAF3IP2 (rs13190932)
Not yet reported South Valley University 50 participants Est. completion 2026-06-10 1 site Stand-aloneOther conditions: Psoriasis, Psoriatic ArthritisView official trial listing → -
Recruiting NCT NCT07089381
Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis.
Not yet reported Ain Shams University 118 participants Est. completion 2026-06-01 1 siteOther conditions: Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention, Inflamation, Antioxidant, Anti Oxidative Stress, Anti Aging, C Reactive Protein, Methotrexate, Quality of Life OutcomesView official trial listing → -
Recruiting NCT NCT07104799
Momelotinib During and After HCT in Myelofibrosis
Not yet reported Massachusetts General Hospital 28 participants Est. completion 2030-01 1 site Stand-aloneOther conditions: Myelofibrosis, Hematopoietic Cell Transplantation (HCT)View official trial listing → -
Recruiting NCT NCT07108530
Efficacy of Integrated Induction-Consolidation Chemotherapy and Transplantation for Adult Acute Myeloid Leukemia: Multicenter Study
Not yet reported Shanxi Bethune Hospital 50 participants Est. completion 2027-08-06 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07124078
A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
Not yet reported Incyte Corporation 60 participants Est. completion 2029-07-31 41 sitesOther conditions: Chronic Graft-versus-host-diseaseView official trial listing → -
Recruiting NCT NCT07138898
Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty
Not yet reported NYU Langone Health 80 participants Est. completion 2028-01 1 site Stand-aloneOther conditions: Rheumatic DiseaseView official trial listing → -
Recruiting NCT NCT07152041
Newly-diagnosed Pediatric Ph-positive B-ALL Protocol
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 150 participants Est. completion 2030-06 24 sitesOther conditions: Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+), Childhood Leukemia, Acute LymphoblasticView official trial listing → -
Recruiting NCT NCT07161336
Role of Methotrexate in Ultrasound Proven Synovitis in Primary Knee OA
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 70 participants Est. completion 2026-08-30 1 siteOther conditions: Osteo Arthritis of the Knee, Synovitis of Knee, MethotrexateView official trial listing → -
Recruiting NCT NCT07168980
Chemotherapy With Rituximab for Aggressive B-NHL in Children and Adolescents
Not yet reported, Not yet reported Children's Cancer Group, China 87 participants Est. completion 2030-06-30 1 siteOther conditions: Mature B-cell Non-Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT07169019
Microbiome and Clinical Response to Probiotics and Methotrexate in Early Psoriasis: a Pilot Study
Not yet reported Alexandria University 24 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: Psoriasis (PsO)View official trial listing → -
Recruiting NCT NCT07171983
A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986454 in Participants With Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 46 participants Est. completion 2027-08-25 9 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT07185373
Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSL
Not yet reported, Not yet reported Huashan Hospital 215 participants Est. completion 2029-07-30 15 sites Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT07186127
Methotrexate Treatment in Cases of Ectopic Pregnancy With Relative Contraindications
Bagcilar Training and Research Hospital 230 participants Est. completion 2026-05-01 1 siteOther conditions: Ectopic PregnancyView official trial listing → -
Recruiting NCT NCT07191431
A Clinical Study on the Efficacy and Safety of Methotrexate (MTX) or Thiotepa (for MTX Intolerance) or Temozolomide (TMZ) Combined With Orelabrutinib and Selinexor in Relapsed/Refractory Primary or Secondary Central Nervous System Lymphoma(SELINA)
Not yet reported Ruijin Hospital 25 participants Est. completion 2029-09-02 1 site Stand-aloneOther conditions: Lymphoma CnsView official trial listing → -
Recruiting NCT NCT07202819
Effect of Neoadjuvant Chemotherapy on MRI Accuracy Before Cystectomy
Not yet reported Assiut University 76 participants Est. completion 2026-08-20 2 sitesOther conditions: Muscle Invasive Bladder CancerView official trial listing → -
Recruiting NCT NCT07227584
ALL Backbone in AYAs
Not yet reported Dana-Farber Cancer Institute 67 participants Est. completion 2035-07-31 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Philadelphia Chromosome-Negative Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia (ALL), LeukemiaView official trial listing → -
Recruiting NCT NCT07228624
Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes
Not yet reported Fred Hutchinson Cancer Center 50 participants Est. completion 2030-09-01 1 site Stand-aloneOther conditions: Myelodysplastic/Myeloproliferative Neoplasm, Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Recruiting NCT NCT07234838
Effect of Anti-Psoriatic Biologics on Risk of Anogenital Warts (CONDYPSO)
Jonathan Krygier 600 participants Est. completion 2028-08-01 3 sitesOther conditions: Psoriasis, Condyloma Acuminata, BiotherapiesView official trial listing → -
Recruiting NCT NCT07242092
Influence of Methotrexate Discontinuation on Immunogenicity After PCV-20 Vaccine in Patients ARDs
Not yet reported University of Sao Paulo General Hospital 192 participants Est. completion 2028-12-30 1 site Stand-aloneOther conditions: Autoimmune Rheumatic DiseasesView official trial listing → -
Recruiting NCT NCT07258043
Efficacy of Dose-Adjusted Regimen on Survival in Frail Adults With Acute Lymphoblastic Leukemia
Hospital General de Mexico 45 participants Est. completion 2026-07-26 1 siteOther conditions: Acute Lymphobkastic Leukemia, Leukemia, Overall SurvivalView official trial listing → -
Recruiting NCT NCT07261306
Comparison Between Oral Methotrexate and Tofacitinib in Chronic Plaque Psoriasis
Not yet reported Lahore General Hospital 75 participants Est. completion 2025-12-25 1 siteOther conditions: PsoriasisView official trial listing → -
Recruiting NCT NCT07280156
A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)
Not yet reported Protalix 150 participants Est. completion 2028-06 35 sites Stand-aloneOther conditions: GoutView official trial listing → -
Recruiting NCT NCT07290803
This Study is a Non-interventional Disease Registry of Adolescent and Adult Patients With Atopic Dermatitis Who Initiate or Switch Any Systemic Treatment
Sanofi 1000 participants Est. completion 2034-01-30 82 sitesOther conditions: Atopic DermatitisView official trial listing → -
Recruiting NCT NCT07294677
CApivasertib, Venetoclax And Low-intensity chemotheRapY for Adults With ALL/LBL
Not yet reported, Not yet reported University of Chicago 104 participants Est. completion 2032-03 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Recruiting NCT NCT07313878
Evaluation of Acute and Chronic Nephrotoxicity in Acute Lymphatic Leukemia Patients Using Ultrasound Localization Microscopy
Not yet reported University of Erlangen-Nürnberg Medical School 30 participants Est. completion 2026-11-30 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukaemias (ALL), Long Term Follow-UpView official trial listing → -
Recruiting NCT NCT07321912
Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma
Not yet reported Milton S. Hershey Medical Center 406 participants Est. completion 2036-06-01 3 sites Stand-aloneObstructive sleep apnea Other conditions: Ewing SarcomaView official trial listing → -
Recruiting NCT NCT07337434
To Check Comparison of Apremilast and Methotrexate Efficacy in Patients With Moderate to Severe Plaque Psoriasis Presented to Tertiary Care Hospital
Not yet reported Syeda Sana Zaman 106 participants Est. completion 2026-06-25 1 site Stand-aloneOther conditions: Chronic Plaque PsoriasisView official trial listing → -
Recruiting NCT NCT07350850
A Multicenter, Prospective Clinical Trial With a Concurrent Control Evaluating Methotrexate Combined With Rituximab,Sintilimab and Pirtobrutinib vs. Investigator-Selected Standard of Care in Treatment-Naive PCNSL
Not yet reported Tongji Hospital 77 participants Est. completion 2029-06-30 4 sites Stand-aloneOther conditions: PCNSL, Primary Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT07352917
Methotrexate for Severe Vulvar Lichen Sclerosus
Not yet reported Clinica Dermatologica Arbache ltda 12 participants Est. completion 2027-01 1 site Stand-aloneOther conditions: Vulvar Lichen SclerosusView official trial listing → -
Recruiting NCT NCT07381556
Cyclosporine Or Methotrexate for Pediatric Alopecia Areata: Routine Clinical Care Effectiveness Study
Not yet reported Erasmus Medical Center 50 participants Est. completion 2027-11-01 1 siteOther conditions: Alopecia Areata(AA), Alopecia Areata (AA), Alopecia Totalis/Universalis, Alopecia Universalis (AU), Alopecia Totalis (AT), Alopecia Areata (& Ophiasis)View official trial listing → -
Recruiting NCT NCT07387926
Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+) or ABL-class Ph-like Acute Lymphoblastic Leukemia (ALL)
Not yet reported, Not yet reported Novartis Pharmaceuticals 50 participants Est. completion 2036-05-30 3 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Leukemia, Lymphoblastic, Acute, Philadelphia-Positive, Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT07388498
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout
Not yet reported Amgen 270 participants Est. completion 2028-06-18 71 sites Stand-aloneOther conditions: Uncontrolled GoutView official trial listing → -
Recruiting NCT NCT07402876
A Clinical Trial Evaluating Patients With Primary Vitreoretinal Lymphoma
Not yet reported Aldeyra Therapeutics, Inc. 20 participants Est. completion 2026-12 1 siteOther conditions: Primary Vitreoretinal LymphomaView official trial listing → -
Recruiting NCT NCT07409103
A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)
Not yet reported Elevara Medicines Limited 180 participants Est. completion 2028-03-31 30 sitesOther conditions: Active Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT07410520
PD-1 Inhibitor Combined With Rituximab, Methotrexate, and Orelabrutinib (PD-1i+RMO) for Newly Diagnosed PCNSL and SCNSL.
Not yet reported The First Affiliated Hospital with Nanjing Medical University 50 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Primary Central Nervous System Lymphoma (PCNSL), Secondary Central Nervous System Lymphoma (SCNSL)View official trial listing → -
Recruiting NCT NCT07443514
Cognitive Impairment in Patients With Diffuse Large B-Cell Lymphoma
Not yet reported Institute of Oncology Ljubljana 3 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Diffuse Large B-Cell LymphomaView official trial listing → -
Recruiting NCT NCT07446400
A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together
Not yet reported Otsuka Pharmaceutical Development & Commercialization, Inc. 48 participants Est. completion 2026-11-07 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Recruiting NCT NCT07463937
A RWS of SC MTX in Chinese RA Patients
Peking University People's Hospital 10000 participants Est. completion 2028-12-31 1 siteOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Recruiting NCT NCT07477457
A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma
Not yet reported Memorial Sloan Kettering Cancer Center 45 participants Est. completion 2028-03-11 7 sites Stand-aloneObstructive sleep apnea Other conditions: MetastasisView official trial listing → -
Recruiting NCT NCT07477691
Immune Modulation During Palynziq® Treatment in Adults (IMPALA)
Not yet reported BioMarin Pharmaceutical 12 participants Est. completion 2027-09-30 12 sites Stand-aloneOther conditions: PhenylketonuriaView official trial listing → -
Recruiting NCT NCT07486843
Preventing Structural Damage in Early Psoriatic Arthritis
Not yet reported Chinese University of Hong Kong 108 participants Est. completion 2028-12-31 1 siteOther conditions: Psoriatic Arthritis (PsA)View official trial listing → -
Recruiting NCT NCT07493161
Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 110 participants Est. completion 2030-03-30 1 site Stand-aloneOther conditions: Ph+ ALLView official trial listing → -
Recruiting NCT NCT07501507
Methotrexate Treatment in Hand Osteoarthritis Refractory to Usual Treatments
Not yet reported, Not yet reported Centre Hospitalier Universitaire de Nice 170 participants Est. completion 2028-02 1 siteOsteoarthritisView official trial listing → -
Recruiting NCT NCT07503652
Clinical Observation of Xeligekimab in the Treatment of Moderate to Severe Palmoplantar Pustulosis
Not yet reported First Hospital of China Medical University 10 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Palmoplantar Pustulosis (PPP)View official trial listing → -
Recruiting NCT NCT07559097
Exploration of the Application of Methotrexate-loaded Drug Vesicles in Intrathecal Injection for Meningeal Metastasis of Lung Cancer
Not yet reported, Not yet reported Henan Cancer Hospital 14 participants Est. completion 2027-12-31 1 siteOther conditions: Leptomeningeal Metastasis From Lung CancerView official trial listing → -
Recruiting NCT NCT07560826
The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma
Not yet reported Wake Forest University Health Sciences 46 participants Est. completion 2028-12 9 sites Stand-aloneObstructive sleep apneaView official trial listing → -
Recruiting NCT NCT07572669
Moxibustion for Steroid-Refractory Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 42 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: Steroid-Refractory Acute Graft-Versus-Host Disease, Acute Graft-Versus-Host Disease, Graft-Versus-Host Disease, Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Recruiting NCT NCT07604987
R-PMDT Regimen in Newly Diagnosed PCNSL
Not yet reported Zou Dehui 33 participants Est. completion 2030-05-20 1 site Stand-aloneOther conditions: Primary Central Nervous System (CNS) LymphomaView official trial listing → -
Recruiting NCT NCT07627893
Complementary Herbal Approach to Rheumatoid Management Study (CHARMS)
Not yet reported, Not yet reported Singapore General Hospital 132 participants Est. completion 2030-06-30 1 site Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Recruiting NCT NCT07678229
BRIDGE-NK: Immunotherapy Versus Chemotherapy Induction Followed by Autologous HSCT in Advanced NKTCL
Not yet reported Rong Tao 150 participants Est. completion 2031-12-31 1 site Stand-aloneOther conditions: Extranodal NK/T-cell LymphomaView official trial listing → -
Recruiting NCT NCT07689630
Anti-CD25 Monoclonal Antibody for Prevention of Acute GVHD After Haploidentical HSCT
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 186 participants Est. completion 2028-05 1 siteOther conditions: Graft Versus Host Disease, Hematologic NeoplasmsView official trial listing → -
Recruiting NCT NCT07721142
Integrated Clinical Study of Traditional Chinese and Western Medicine for Refractory Rheumatoid Arthritis
Not yet reported Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine 300 participants Est. completion 2028-03-15 1 site Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Recruiting NCT NCT07724873
Study to Evaluate the Safety and Effectiveness of Withaferin A as a Treatment to Prevent GvHD in Transplant Patients
Not yet reported, Not yet reported Tata Memorial Centre 54 participants Est. completion 2029-12-03 2 sites Stand-aloneOther conditions: Hematopoietic Stem Cell Transplant (HSCT), GVHD - Graft-Versus-Host Disease, Hematological MalignancyView official trial listing → -
Recruiting NCT NCT07730723
The Effect of Nicorandil on Rheumatoid Arthritis Patients
Not yet reported, Not yet reported Ain Shams University 70 participants Est. completion 2027-07 1 siteOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Recruiting NCT NCT07768436
A Study of Cyclophosphamide, Methotrexate, Fluorouracil (CMF) for People With Breast Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 76 participants Est. completion 2030-08-11 7 sites Stand-aloneOther conditions: Adenocarcinoma of the Breast, Breast Cancer, Triple Negative Breast CancerView official trial listing → -
Recruiting NCT NCT07842835
Registry of an Integrated Longitudinal Multimodal Biospecimen Biobank for Primary CNS Lymphoma in China
Xiaohui Ren 400 participants Est. completion 2031-07-31 3 sitesOther conditions: Primary Central Nervous System Lymphoma (PCNSL)View official trial listing → -
Recruiting NCT NCT07843381
Clinical Efficacy of Telitacicept in Sjögren's Disease With Interstitial Lung Disease
Peking University People's Hospital 60 participants Est. completion 2027-11-20 1 siteOther conditions: Sjögren's Disease, Interstitial Lung DiseaseView official trial listing → -
Recruiting NCT NCT07844772
Serum Substance P, Neuropathic Pain, and Central Sensitization Across Treatment Groups in Chronic Plaque Psoriasis
Istanbul Training and Research Hospital 100 participants Est. completion 2027-01 1 siteOther conditions: Chronic Plaque-type PsoriasisView official trial listing → -
Terminated NCT NCT00000361
Autoimmunity in Inner Ear Disease
Not yet reported National Institute on Deafness and Other Communication Disorders (NIDCD) Est. completion 2002-11 9 sitesOther conditions: Hearing Loss, SensorineuralView official trial listing → -
Completed NCT NCT00000395
Antifolate Effectiveness in Arthritis
Not yet reported University of Alabama at Birmingham 40 participants Est. completion 2002-08 1 site Stand-aloneOther conditions: Rheumatoid Arthritis, Adjuvant ArthritisView official trial listing → -
Completed NCT NCT00000658
A Phase III Randomized Trial of Low-Dose Versus Standard-Dose mBACOD Chemotherapy With rGM-CSF for Treatment of AIDS-Associated Non-Hodgkin's Lymphoma
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 250 participants Est. completion 1996-02 22 sitesOther conditions: Lymphoma, Non-Hodgkin, HIV InfectionsView official trial listing → -
Completed NCT NCT00000689
Phase I Trial of mBACOD and Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in AIDS-Associated Large Cell, Immunoblastic, and Small Non-cleaved Lymphoma
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 18 participants Est. completion 1991-03 1 siteOther conditions: Lymphoma, Non-Hodgkin, HIV InfectionsView official trial listing → -
Completed NCT NCT00000703
Chemotherapy and Azidothymidine, With or Without Radiotherapy, for High Grade Lymphoma in AIDS-Risk Group Members
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 45 participants Est. completion 1990-03 14 sitesOther conditions: Lymphoma, Non-Hodgkin, HIV InfectionsView official trial listing → -
Terminated NCT NCT00000723
The Use of Chemotherapy Plus Radiotherapy Plus Azidothymidine in Patients With AIDS-Related Lymph Node Cancer
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 45 participants Est. completion 1990-03 1 siteOther conditions: Lymphoma, Non-Hodgkin, HIV InfectionsView official trial listing → -
Completed NCT NCT00000834
A Phase I Study of Methotrexate for HIV Infection
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 30 participants Est. completion 2002-06 7 sitesOther conditions: HIV InfectionsView official trial listing → -
Completed NCT NCT00001256
Steroids and Methotrexate to Treat Systemic Vasculitis
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 100 participants Est. completion 2004-02 1 siteOther conditions: Inflammation, Vasculitis, Wegener's GranulomatosisView official trial listing → -
Completed NCT NCT00001298
A Trial of Carboxypeptidase-G2 (CPDG2) and Thymidine for the Management of Patients With Methotrexate Toxicity and Renal Dysfunction
Not yet reported National Cancer Institute (NCI) 10 participants Est. completion 2001-01 1 siteOther conditions: Kidney DiseasesView official trial listing → -
Completed NCT NCT00001473
Cyclophosphamide and Prednisone Followed by Methotrexate To Treat Vasculitides
National Institute of Allergy and Infectious Diseases (NIAID) 100 participants Est. completion 2004-03 1 siteOther conditions: Vasculitis, Wegener's GranulomatosisView official trial listing → -
Completed NCT NCT00001498
A Pilot Trial of Sequential Chemotherapy With Antimetabolite Induction, High-Dose Alkylating Agent Consolidation With Peripheral Blood Progenitor Cell Support, and Intensification With Paclitaxel and Doxorubicin for Patients With High-Risk Breast Cancer
Not yet reported National Cancer Institute (NCI) 55 participants Est. completion 2000-12 1 siteOther conditions: Breast Cancer, Breast NeoplasmsView official trial listing → -
Completed NCT NCT00001677
Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthritis: Safety, Tolerance and Efficacy
Not yet reported National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 40 participants Est. completion 2000-04 1 siteOther conditions: Arthritis, Rheumatoid, SynovitisView official trial listing → -
Terminated NCT NCT00001880
Stem Cell Transplantation for Metastatic Solid Tumors
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 42 participants Est. completion 2020-08-13 1 site Stand-aloneOther conditions: Neoplasm MetastasisView official trial listing → -
Completed NCT NCT00001901
Etanercept to Treat Wegener's Granulomatosis
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 60 participants Est. completion 2005-03 1 siteOther conditions: Vasculitis, Wegener's GranulomatosisView official trial listing → -
Completed NCT NCT00002456
Graft-Versus-Host Disease Prevention in Treating Patients Who Are Undergoing Bone Marrow Transplantation
Not yet reported Fred Hutchinson Cancer Center Est. completion 2002-04 1 siteOther conditions: Graft Versus Host Disease, Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00002463
Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors
Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2008-01 1 site Stand-aloneOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00002471
Combination Chemotherapy in Treating Patients With Acute B-Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2003-01 4 sitesOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00002476
Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Head and Neck Cancer
Not yet reported Cancer Research UK Est. completion 2010-01 7 sitesOther conditions: Head and Neck CancerView official trial listing → -
Status unknown NCT NCT00002487
Methotrexate Plus Dipyridamole in Treating Patients With Advanced Ovarian Cancer
Not yet reported Ottawa Regional Cancer Centre 2 sitesOther conditions: Ovarian CancerView official trial listing → -
Completed NCT NCT00002489
Combination Chemotherapy in Treating Children With Non-testicular Malignant Germ Cell Tumors
Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2002-06 1 siteOther conditions: Extragonadal Germ Cell Tumor, Ovarian CancerView official trial listing → -
Completed NCT NCT00002494
Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia
Not yet reported Alliance for Clinical Trials in Oncology 134 participants Est. completion 2006-01 23 sites Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Status unknown NCT NCT00002498
Combination Chemotherapy Compared With Mitoxantrone in Treating Older Patients With Advanced Breast Cancer
Not yet reported Leiden University Medical Center 2 sitesOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT00002499
Combination Chemotherapy in Treating Children With Relapsed Acute Lymphocytic Leukemia
Not yet reported, Not yet reported Grupo Argentino de Tratamiento de la Leucemia Aguda 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002514
Stem Cell Transplantation Compared With Standard Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia in First Remission
Not yet reported Eastern Cooperative Oncology Group 1929 participants 94 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002524
Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma
Not yet reported M.D. Anderson Cancer Center 46 participants Est. completion 2005-10 2 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Status unknown NCT NCT00002531
Combination Chemotherapy in Treating Adults With Acute Lymphocytic Leukemia
Not yet reported Johann Wolfgang Goethe University Hospital 1 siteOther conditions: LeukemiaView official trial listing → -
Status unknown NCT NCT00002532
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia
Not yet reported Hannover Medical School 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002542
Tamoxifen in Treating Women With High-Risk Breast Cancer
Not yet reported NCIC Clinical Trials Group 672 participants Est. completion 2011-01-11 48 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00002547
Chemotherapy and Bone Marrow Transplantation in Treating Patients Acute Myeloid With Leukemia or Myelodysplastic Syndrome
Not yet reported Barbara Ann Karmanos Cancer Institute 280 participants Est. completion 2003-10 1 siteOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00002552
Chemotherapy Plus Bone Marrow Transplantation in Treating Patients With Refractory Non-Hodgkin's Lymphoma, Hodgkin's Disease, or Multiple Myeloma
Not yet reported Barbara Ann Karmanos Cancer Institute 40 participants Est. completion 2003-10 1 siteOther conditions: Lymphoma, Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00002554
Monoclonal Antibody Followed by Bone Marrow Transplantation in Treating Patients With Acute Myelogenous Leukemia in Remission or First Relapse
Not yet reported Fred Hutchinson Cancer Center 30 participants Est. completion 1999-12Other conditions: LeukemiaView official trial listing → -
Status unknown NCT NCT00002557
Combination Chemotherapy in Patients With Advanced or Recurrent Mycosis Fungoides
Not yet reported National Cancer Institute (NCI) 3 participants 1 siteOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00002571
SWOG-9320 Combination Chemotherapy, Radiation Therapy, and Antiviral Therapy in Treating Patients With AIDS-Related Lymphoma
Not yet reported SWOG Cancer Research Network 52 participants Est. completion 2011-07 85 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00002578
Gallium Nitrate in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma
Not yet reported Roswell Park Cancer Institute 35 participants 3 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00002579
Tamoxifen Following Combination Chemotherapy in Treating Women With Operable Invasive Breast Cancer
Not yet reported Scottish Cancer Therapy Network 2000 participants 10 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00002580
Tamoxifen, Ovarian Ablation, and/or Combination Chemotherapy in Treating Premenopausal Women With Stage I, Stage II, or Stage IIIA Invasive Breast Cancer
Not yet reported Scottish Cancer Therapy Network 1000 participants 10 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00002581
Tamoxifen With or Without Combination Chemotherapy in Treating Postmenopausal Women With Operable Invasive Breast Cancer
Not yet reported Scottish Cancer Therapy Network 1000 participants 9 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00002582
Tamoxifen, Ovarian Ablation, and/or Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA Breast Cancer
Not yet reported Institute of Cancer Research, United Kingdom 6000 participants Est. completion 2007-04 2 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00002590
Combination Chemotherapy in Treating Children With Lymphoma
Not yet reported Children's Oncology Group 221 participants Est. completion 2007-03 33 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00002598
Combination Chemotherapy and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 30 participants Est. completion 2004-06 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002618
Combination Chemotherapy in Treating Pediatric Patients With Advanced-Stage Large Cell Lymphoma
Not yet reported Children's Oncology Group 242 participants Est. completion 2006-09 10 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00002657
SWOG-9239 Reduction of Immunosuppression Plus Interferon Alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant
Not yet reported SWOG Cancer Research Network 20 participants Est. completion 2011-07 86 sites Stand-aloneOther conditions: Lymphoma, Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00002665
SWOG-9400 Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Previously Untreated Acute Lymphocytic Leukemia
Not yet reported SWOG Cancer Research Network 50 participants Est. completion 2003-12 83 sitesOther conditions: Leukemia, Neutropenia, ThrombocytopeniaView official trial listing → -
Completed NCT NCT00002676
Chemotherapy and Whole-Brain Radiation Therapy in Treating Patients With Primary Central Nervous System Non- Hodgkin's Lymphoma
Not yet reported Alliance for Clinical Trials in Oncology 36 participants Est. completion 2006-10 21 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00002691
Combination Chemotherapy in Treating Pediatric Patients With Stage III or IV Non-Hodgkin's Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2000-06 1 siteOther conditions: LymphomaView official trial listing → -
Suspended NCT NCT00002696
Combination Chemotherapy in Treating Women With Stage III Breast Cancer
Not yet reported Grupo Oncologico Cooperativo del Sur 7 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00002700
Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 392 participants 44 sitesOther conditions: Leukemia, LymphomaView official trial listing → -
Status unknown NCT NCT00002701
Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Promyelocytic Leukemia
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 750 participants 71 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002704
Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 156 participants 70 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002722
High-Dose Chemotherapy in Treating Patients With Advanced Stomach Cancer
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 135 participantsOther conditions: Gastric CancerView official trial listing → -
Completed NCT NCT00002744
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 1970 participants Est. completion 2007-03 34 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002755
Standard Chemotherapy Compared With High-Dose Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Women With Breast Cancer
Not yet reported Scottish Cancer Therapy Network 600 participants Est. completion 1999-06 21 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00002757
TITLE:Less Intensive Therapy for Children With Non-Hodgkin's Lymphoma
Not yet reported Children's Oncology Group 1148 participants Est. completion 2009-10 2 sitesOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00002766
Comparison of Two Combination Chemotherapy Regimens in Treating Adults With Previously Untreated Leukemia or Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 170 participants Est. completion 2011-09 7 sites Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00002768
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Acute Myeloid Leukemia in Second Remission
Not yet reported Alliance for Clinical Trials in Oncology 51 participants Est. completion 2009-03 3 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002784
High-Dose Combination Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Combination Chemotherapy in Treating Women With High-Risk Breast Cancer
Not yet reported ETOP IBCSG Partners Foundation 344 participants Est. completion 2011-12 11 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00002785
Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group Est. completion 2007-03 33 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002789
Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myeloid Leukemia
Not yet reported Fred Hutchinson Cancer Center 100 participants Est. completion 2001-09 1 siteOther conditions: LeukemiaView official trial listing → -
Withdrawn NCT NCT00002790
Prevention of Graft-Versus-Host Disease in Patients With Hematologic Malignancies Who Are Receiving a Bone Marrow Transplant
Not yet reported, Not yet reported Fred Hutchinson Cancer CenterOther conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00002792
Combination Chemotherapy Plus Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloproliferative Disorders
Not yet reported Fred Hutchinson Cancer Center 20 participants Est. completion 2003-04 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00002798
Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Not yet reported National Cancer Institute (NCI) 880 participants 1 site Stand-aloneOther conditions: Childhood Acute Erythroleukemia (M6), Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloblastic Leukemia With Maturation (M2), Childhood Acute Myeloblastic Leukemia Without Maturation (M1), Childhood Acute Myelomonocytic Leukemia (M4), Childhood Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes, Refractory Anemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Excess Blasts in Transformation, Refractory Anemia With Ringed Sideroblasts, Secondary Myelodysplastic Syndromes, Untreated Childhood Acute Myeloid Leukemia and Other Myeloid MalignanciesView official trial listing → -
Completed NCT NCT00002805
Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported Children's Oncology Group 115 participants Est. completion 2008-06 38 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002809
Bone Marrow Transplant Plus Cyclophosphamide and Total-Body Irradiation in Treating Patients With Hematologic Cancer
Not yet reported Temple University 10 participants Est. completion 2003-12 1 siteOther conditions: Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00002812
Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia
Not yet reported Children's Oncology Group 2078 participants 35 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002816
Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 120 participants Est. completion 2006-04 33 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002831
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous or Acute Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 24 participants Est. completion 2002-12-31 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002835
Combination Chemotherapy in Treating Patients With Lymphoma
Not yet reported M.D. Anderson Cancer Center 116 participants Est. completion 2004-02-04 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00002865
High-Intensity, Brief-Duration Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia
Not yet reported Wake Forest University Health Sciences 25 participants Est. completion 2001-08 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002919
Combination Chemotherapy in Treating Patients With Stage II Bladder Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 30 participants Est. completion 2003-01 1 siteOther conditions: Bladder CancerView official trial listing → -
Terminated NCT NCT00002961
Chemotherapy With or Without Total-Body Irradiation Prior to Bone Marrow Transplantation in Treating Children With Acute Lymphoblastic Leukemia
Not yet reported Children's Hospital of Philadelphia 43 participants Est. completion 2001-02 18 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00002970
506U78 in Treating Patients With Refractory Hematologic Cancer
Not yet reported National Cancer Institute (NCI) 148 participants 1 site Stand-aloneOther conditions: Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Lymphoblastic Lymphoma, T-cell Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00003012
Combination Chemotherapy Following Surgery in Treating Women With Early Stage Breast Cancer
Not yet reported Scottish Cancer Therapy Network 1000 participants 10 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00003013
Chemotherapy Plus Surgery in Treating Women With Breast Cancer
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 450 participants Est. completion 2009-03 28 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00003019
Vinblastine and Methotrexate in Treating Children With Desmoid Tumors
Not yet reported Children's Oncology Group 28 participants Est. completion 2006-09 39 sites Stand-aloneOther conditions: Desmoid TumorView official trial listing → -
Terminated NCT NCT00003056
Prevention of Graft-Versus-Host Disease in Patients With Advanced Leukemia or Lymphoma Who Are Eligible for Peripheral Stem Cell Transplantation
Not yet reported Baxalta now part of Shire 105 participants Est. completion 2003-06-01 13 sitesOther conditions: Leukemia, Lymphoma, Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT00003061
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Primary CNS Lymphoma
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 50 participants 7 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00003215
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Aggressive Non-Hodgkin's Lymphoma
Not yet reported Swiss Cancer Institute 400 participants Est. completion 2004-03 12 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00003217
Combination Chemotherapy in Treating Children With Stage III or Stage IV Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 20 participants Est. completion 2006-09 14 sites Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Status unknown NCT NCT00003261
Chemotherapy and Radiation Therapy in Treating Patients With HIV-Related Primary Central Nervous System Lymphoma
Not yet reported Centro di Riferimento Oncologico - Aviano 14 participants 1 siteOther conditions: LymphomaView official trial listing → -
Withdrawn NCT NCT00003273
Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Brain Tumor
Not yet reported NYU Langone Health 19 sitesOther conditions: Brain and Central Nervous System Tumors, Neuroblastoma, Retinoblastoma, SarcomaView official trial listing → -
Completed NCT NCT00003311
Combination Chemotherapy in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 19 participants Est. completion 2007-04-18 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00003376
Two-Drug Combination Chemotherapy Compared With Four-Drug Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium
Not yet reported Eastern Cooperative Oncology Group 330 participants 50 sitesOther conditions: Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral CancerView official trial listing → -
Completed NCT NCT00003388
Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma
Not yet reported Eastern Cooperative Oncology Group 38 participants 5 sitesOther conditions: LymphomaView official trial listing → -
Status unknown NCT NCT00003423
Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma
Not yet reported United Kingdom Children's Cancer Study Group 100 participants 1 siteOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00003436
Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myeloid Leukemia
Not yet reported Medical Research Council 2000 participants Est. completion 2005-12 1 siteOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT00003437
Hormone Therapy Plus Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
Not yet reported Medical Research Council 1800 participants 1 siteOther conditions: LeukemiaView official trial listing → -
Withdrawn NCT NCT00003536
Methotrexate With or Without Antineoplaston Therapy in Treating Postmenopausal Women With Advanced Refractory Breast Cancer
Not yet reported Burzynski Research Institute 1 siteOther conditions: Stage IV Breast Cancer, Recurrent Breast CancerView official trial listing → -
Completed NCT NCT00003549
S9716: Combination Chemotherapy in Treating Patients With Merkel Cell Cancer
Not yet reported SWOG Cancer Research Network 80 participants Est. completion 2003-01 84 sitesOther conditions: Neuroendocrine Carcinoma of the SkinView official trial listing → -
Completed NCT NCT00003577
Combination Chemotherapy With or Without Epirubicin in Treating Women With Stage I or Stage II Breast Cancer
Not yet reported University Hospital Birmingham 2000 participants Est. completion 2008-09 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00003592
Methotrexate Compared With Paclitaxel in Treating Patients With Advanced Head and Neck Cancer
Not yet reported Eastern Cooperative Oncology Group 230 participants Est. completion 2004-03-02 20 sitesOther conditions: Head and Neck CancerView official trial listing → -
Completed NCT NCT00003593
Chemotherapy in Treating Children With Down Syndrome and Myeloproliferative Disorder, Acute Myelogenous Leukemia, or Myelodysplastic Syndrome
Not yet reported Children's Oncology Group 254 participants Est. completion 2012-04 237 sites Stand-aloneOther conditions: Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00003632
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Central Nervous System Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 30 participants 1 siteOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT00003640
Transurethral Resection and Combination Chemotherapy in Treating Patients With Stage II or Stage III Bladder Cancer
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 73 participants 1 siteOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT00003650
Combination Chemotherapy in Treating Children With Non-Hodgkin's Lymphoma
Not yet reported UNICANCER 179 participants Est. completion 2013-11 1 siteOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00003671
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia
Not yet reported Children's Oncology Group 59 participants Est. completion 2009-02 57 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Status unknown NCT NCT00003680
Standard Chemotherapy Compared With High-Dose Chemotherapy Plus Peripheral Stem Cell Transplant in Treating Women With Advanced or Inflammatory Breast Cancer
Not yet reported Scottish Cancer Therapy Network 300 participants 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00003700
Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia
Not yet reported Alliance for Clinical Trials in Oncology 163 participants Est. completion 2010-01 50 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00003701
Combination Chemotherapy in Treating Patients With Bladder Cancer
Not yet reported Eastern Cooperative Oncology Group 490 participants Est. completion 2007-06-15 13 sitesOther conditions: Bladder Cancer, Urethral CancerView official trial listing → -
Completed NCT NCT00003702
Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia
Not yet reported Gynecologic Oncology Group 240 participants 1 site Stand-aloneOther conditions: Good Prognosis Metastatic Gestational Trophoblastic Tumor, Hydatidiform Mole, Non-Metastatic Gestational Trophoblastic Tumor, Uterine Corpus ChoriocarcinomaView official trial listing → -
Status unknown NCT NCT00003728
Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 1500 participants 23 sitesOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00003776
Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma
Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2000-03 1 siteOther conditions: SarcomaView official trial listing → -
Completed NCT NCT00003838
Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 202 participants Est. completion 2020-06-18 1 site Stand-aloneOther conditions: Myeloproliferative Disorders, Acute Myelogenous Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00003868
Radiolabeled Monoclonal Antibody, Cyclophosphamide, and Total Body Irradiation Followed By Donor Stem Cell Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia
Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2005-03 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00003870
Monoclonal Antibody Therapy, Cyclophosphamide, and Total-Body Irradiation Followed by Peripheral Stem Cell Transplantation in Treating Patients With Advanced Recurrent Acute Lymphocytic Leukemia
Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2001-11 2 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00003893
Adjuvant Chemotherapy Plus Radiation Therapy in Treating Women With Early-Stage Breast Cancer
Not yet reported University Hospital Birmingham 2250 participants Est. completion 2006-04 1 siteOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT00003910
Methotrexate With or Without Cyclophosphamide in Treating Patients With Lymphocytic Leukemia
Not yet reported Eastern Cooperative Oncology Group 59 participants Est. completion 2012-03 68 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00003934
Tretinoin, Cytarabine, and Daunorubicin Hydrochloride With or Without Arsenic Trioxide Followed by Tretinoin With or Without Mercaptopurine and Methotrexate in Treating Patients With Acute Promyelocytic Leukemia
Not yet reported National Cancer Institute (NCI) 420 participants 2 sites Stand-aloneOther conditions: Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Promyelocytic Leukemia (M3), Childhood Acute Promyelocytic Leukemia (M3), Untreated Adult Acute Myeloid Leukemia, Untreated Childhood Acute Myeloid Leukemia and Other Myeloid MalignanciesView official trial listing → -
Completed NCT NCT00003937
Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma
Not yet reported Children's Oncology Group 253 participants Est. completion 2008-06 148 sites Stand-aloneOther conditions: Cardiac Toxicity, SarcomaView official trial listing → -
Completed NCT NCT00003953
Chemotherapy Followed by Surgery in Treating Women With Stage II or Stage III Breast Cancer
Not yet reported Case Comprehensive Cancer Center 39 participants Est. completion 2013-01 2 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00004162
Liposomal Doxorubicin Plus Combination Chemotherapy in Treating Patients With AIDS-Associated Non-Hodgkin's Lymphoma
Not yet reported University of Alabama at Birmingham 48 participants Est. completion 2001-01 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00004228
Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma
Not yet reported Children's Oncology Group 393 participants Est. completion 2015-03-31 176 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00004231
Combination Chemotherapy, Bone Marrow or Peripheral Stem Cell Transplantation, and/or Biological Therapy in Treating Patients With Stage III or Stage IV Mantle Cell Lymphoma
Not yet reported Northwestern University Est. completion 2006-08 1 siteOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00004323
Phase II Study of Bone Marrow Transplantation Using Related Donors in Patients With Aplastic Anemia
Not yet reported National Center for Research Resources (NCRR) 10 participants 1 siteOther conditions: Aplastic AnemiaView official trial listing → -
Completed NCT NCT00004567
Comparison of Treatments to Maintain Disease Remission in Patients With Wegener's Granulomatosis and Related Vasculitis Syndromes
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 75 participants Est. completion 2004-06 1 siteOther conditions: Vasculitis, Wegener's GranulomatosisView official trial listing → -
Completed NCT NCT00004686
Phase II Randomized Study of Glucocorticoids With or Without Methotrexate for Treatment of Giant Cell Arteritis
Not yet reported The Cleveland Clinic 300 participants Est. completion 1999-09Other conditions: Giant Cell ArteritisView official trial listing → -
Completed NCT NCT00004748
Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis
Not yet reported National Center for Research Resources (NCRR) 90 participantsOther conditions: Liver Cirrhosis, BiliaryView official trial listing → -
Completed NCT NCT00004784
Phase III Randomized Study of Ursodiol With Vs Without Methotrexate for Primary Biliary Cirrhosis
Not yet reported National Center for Research Resources (NCRR) 315 participantsOther conditions: Liver Cirrhosis, BiliaryView official trial listing → -
Withdrawn NCT NCT00004878
Donor Lymphocytes to Prevent Graft-Versus-Host Disease in Patients With Chronic Myeloid Leukemia
Not yet reported Jonsson Comprehensive Cancer CenterOther conditions: Graft Versus Host Disease, LeukemiaView official trial listing → -
Terminated NCT NCT00005047
4B951, Combination Chemotherapy in Treating Patients With Bladder Cancer
Not yet reported SWOG Cancer Research Network 521 participants Est. completion 2014-12 74 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT00005086
Combination Chemotherapy in Treating Patients With Stage IV Locally Advanced or Metastatic Bladder Cancer
Not yet reported University of Chicago 6 participants Est. completion 2005-04 4 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT00005585
Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 838 participants 123 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00005596
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 1076 participants Est. completion 2007-07 123 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00005603
Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 276 participants 20 sitesOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00005641
Removal of T Cells to Prevent Graft-Versus-Host Disease in Patients Undergoing Bone Marrow Transplantation
Not yet reported H. Lee Moffitt Cancer Center and Research Institute Est. completion 2000-09 1 siteOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00005802
Chemotherapy Followed by Donor White Blood Cells Plus Interleukin-2 in Treating Patients With Acute Myeloid or Lymphocytic Leukemia
Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2005-03 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00005854
Bone Marrow Transplantation in Treating Patients With Hematologic Cancer
Not yet reported Fred Hutchinson Cancer Center Est. completion 2000-10 4 sitesOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00005866
S9920 Busulfan Compared With Cyclophosphamide in Patients Undergoing Total-Body Irradiation Plus Peripheral Stem Cell Transplantation for Advanced Myelodysplastic Syndrome or Related Acute Myeloid Leukemia
Not yet reported SWOG Cancer Research Network 240 participants Est. completion 2006-03 66 sites Stand-aloneOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00005945
Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 3054 participants Est. completion 2008-06 130 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00005977
Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia
Not yet reported Children's Oncology Group 83 participants Est. completion 2006-09 119 sites Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00005988
Bone Marrow Transplantation With Specially Treated Bone Marrow in Treating Patients With Hematologic Cancer That Have Not Responded to Previous Therapy
Not yet reported Dana-Farber Cancer Institute 5 participants Est. completion 2002-03-08 2 sites Stand-aloneOther conditions: Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes, MyelomaView official trial listing → -
Completed NCT NCT00006033
Interleukin-2 Gene or Methotrexate in Treating Patients With Recurrent or Refractory Stage III or Stage IV Head and Neck Cancer
Not yet reported H. Lee Moffitt Cancer Center and Research Institute Est. completion 2004-06 1 siteOther conditions: Head and Neck CancerView official trial listing → -
Terminated NCT NCT00006054
Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
Not yet reported Fairview University Medical Center Est. completion 2002-12 1 siteOther conditions: Immunologic Deficiency Syndromes, Chediak-Higashi Syndrome, Common Variable Immunodeficiency, Graft Versus Host Disease, X-Linked Lymphoproliferative Syndrome, Familial Erythrophagocytic Lymphohistiocytosis, Hemophagocytic Lymphohistiocytosis, X-linked Agammaglobulinemia, Wiskott-Aldrich Syndrome, Chronic Granulomatous Disease, X-linked Hyper IgM Syndrome, Severe Combined Immunodeficiency, Leukocyte Adhesion Deficiency Syndrome, Virus-Associated Hemophagocytic SyndromeView official trial listing → -
Status unknown NCT NCT00006056
Pilot Study of Unrelated Donor Hematopoietic Stem Cell Transplantation in Patients With Life Threatening Hemophagocytic Disorders
Not yet reported Fairview University Medical Center 40 participants 1 siteOther conditions: Chediak-Higashi Syndrome, Graft Versus Host Disease, X-Linked Lymphoproliferative Syndrome, Familial Erythrophagocytic Lymphohistiocytosis, Hemophagocytic Lymphohistiocytosis, Virus-Associated Hemophagocytic SyndromeView official trial listing → -
Completed NCT NCT00006168
Ursodiol-Methotrexate for Primary Biliary Cirrhosis
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Est. completion 2004-03 12 sitesOther conditions: Liver Cirrhosis, BiliaryView official trial listing → -
Completed NCT NCT00006184
Chemotherapy, Stem Cell Transplantation and Donor and Patient Vaccination for Treatment of Multiple Myeloma
Not yet reported National Cancer Institute (NCI) 20 participants Est. completion 2008-01-12 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00006258
Combination Chemotherapy Followed by Radiation Therapy in Treating Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma
Not yet reported Children's Hospital Los Angeles Est. completion 2005-01 3 sitesOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Withdrawn NCT NCT00006451
Bone Marrow Transplantation in Treating Patients With Leukemia
Not yet reported Masonic Cancer Center, University of Minnesota Est. completion 2000-11 1 siteOther conditions: Graft Versus Host Disease, Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00006455
Combination Chemotherapy in Treating Children With Anaplastic Large Cell Lymphoma (ALCL 99)
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 885 participants Est. completion 2020-09-03 10 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00006747
Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma
Not yet reported Alliance for Clinical Trials in Oncology 4 participants Est. completion 2003-02 48 sites Stand-aloneOther conditions: Graft Versus Host Disease, LymphomaView official trial listing → -
Completed NCT NCT00008151
Gemtuzumab Ozogamicin, Fludarabine, and Total-body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported Fred Hutchinson Cancer Center Est. completion 2002-07 1 siteOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00012051
Chemotherapy and Peripheral Stem Cell Transplant With or Without Monoclonal Antibody Therapy in Treating Patients With Non-Hodgkin's Lymphoma
Not yet reported Commissie Voor Klinisch Toegepast Onderzoek 340 participants Est. completion 2007-10 17 sitesOther conditions: LymphomaView official trial listing → -
Status unknown NCT NCT00012311
Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Chemotherapy Alone in Treating Women With Stage IV Breast Cancer
Not yet reported Herbert Irving Comprehensive Cancer Center 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00014274
Combination Chemotherapy in Treating Patients With Transitional Cell Cancer of the Urothelium
Not yet reported, Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 238 participants 29 sitesOther conditions: Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral CancerView official trial listing → -
Completed NCT NCT00014469
Combination Chemotherapy Followed by Bone Marrow Transplantation in Treating Patients With Advanced Hematologic Cancer
Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2007-05 1 siteOther conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00015873
Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia
Not yet reported Dutch Childhood Oncology Group 350 participants Est. completion 2009-12 33 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00016302
Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 100 participants 1 site Stand-aloneOther conditions: T-cell Childhood Acute Lymphoblastic Leukemia, Untreated Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00018967
Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Methotrexate
Not yet reported National Cancer Institute (NCI) 10 participants 103 sitesOther conditions: Neurotoxicity, Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol SpecificView official trial listing → -
Withdrawn NCT NCT00019409
Radiation Therapy to the Head or Intrathecal Chemotherapy Plus High Dose Cytarabine in Preventing CNS Disease in Children With Acute Lymphoblastic Leukemia
Not yet reported National Institutes of Health Clinical Center (CC) Est. completion 2001-07 6 sitesOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00019864
Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma
Not yet reported National Cancer Institute (NCI) 100 participants Est. completion 2011-10 4 sitesOther conditions: Cardiac Toxicity, SarcomaView official trial listing → -
Completed NCT NCT00020943
Chemotherapy and Rituximab With Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma
Not yet reported Alliance for Clinical Trials in Oncology 79 participants Est. completion 2009-09 81 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00022126
Combination Chemotherapy With or Without Donor Bone Marrow Transplantation in Treating Infants With Previously Untreated Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 6 participants Est. completion 2006-04 51 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00022516
Low-dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-negative Early Breast Cancer
Not yet reported ETOP IBCSG Partners Foundation 1086 participants Est. completion 2016-08 36 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00022737
Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 220 participants 1 site Stand-aloneOther conditions: Childhood Acute Lymphoblastic Leukemia in Remission, Recurrent Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00023998
Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma
Not yet reported National Cancer Institute (NCI) 80 participants Est. completion 2007-05 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT00024050
Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Myelodysplastic Syndrome
Not yet reported Fred Hutchinson Cancer Center Est. completion 2007-08 1 siteOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00025545
Filgrastim-Treated Donor Peripheral Stem Cell Transplantation in Treating Patients With Acute Leukemia</p>
Not yet reported Fred Hutchinson Cancer Center Est. completion 2002-10 1 siteOther conditions: LeukemiaView official trial listing → -
Status unknown NCT NCT00025636
Combination Chemotherapy and Peripheral Stem Cell Transplant in Treating Patients With Relapsed Hodgkin's Lymphoma
Not yet reported German Hodgkin's Lymphoma Study Group 220 participants 44 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00027547
Combination Chemotherapy and Total-Body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2004-07 3 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00027573
Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic or Unresectable Kidney Cancer
Not yet reported Alliance for Clinical Trials in Oncology 36 participants Est. completion 2006-06 6 sites Stand-aloneOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00027924
Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia or Myelodysplastic Syndrome
Not yet reported Fred Hutchinson Cancer Center Est. completion 2003-05 1 siteOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00028509
Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201
Children's Oncology Group 66 participants 26 sitesOther conditions: Long-term Effects Secondary to Cancer Therapy in Children, NeurotoxicityView official trial listing → -
Completed NCT NCT00028600
Peripheral Stem Cell Transplant in Treating Patients With Multiple Myeloma
Not yet reported Alliance for Clinical Trials in Oncology 60 participants Est. completion 2010-02 15 sites Stand-aloneOther conditions: Multiple Myeloma, Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00028756
Comparison of Immediate and Delayed Adjuvant Chemotherapy in Treating Patients Who Have Undergone a Radical Cystectomy for Stage III or Stage IV Transitional Cell Carcinoma of the Bladder Urothelium
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 285 participants Est. completion 2014-07 Stand-aloneOther conditions: Stage III Bladder Cancer, Stage IV Bladder Cancer, Transitional Cell Carcinoma of the BladderView official trial listing → -
Completed NCT NCT00029523
DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor
Not yet reported Pacira Pharmaceuticals, Inc 100 participants Est. completion 2004-11 23 sitesOther conditions: Meningeal NeoplasmsView official trial listing → -
Completed NCT NCT00030264
Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas
Not yet reported Children's Hospital of Philadelphia 23 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: Neurofibromatosis Type 1, Precancerous ConditionView official trial listing → -
Status unknown NCT NCT00033683
Combination Chemotherapy in Treating Women With Resected Breast Cancer
Not yet reported Institute of Cancer Research, United Kingdom 69 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00035074
A Pharmacokinetic Study to Determine the Oral Bioavailability of Methotrexate in Patients With Inflammatory Bowel Disease
Not yet reported National Center for Research Resources (NCRR) 1 siteOther conditions: Inflammatory Bowel DiseaseView official trial listing → -
Terminated NCT NCT00035958
Understanding the Pathogenesis and Treatment of Childhood Onset Dermatomyositis
Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 75 participants Est. completion 2002-08 1 siteOther conditions: DermatomyositisView official trial listing → -
Completed NCT NCT00036153
Study to Assess Efficacy of Tacrolimus + Methotrexate Versus Placebo + Methotrexate in Treatment of Rheumatoid Arthritis
Not yet reported Astellas Pharma Inc 210 participants Est. completion 2004-01 45 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00036374
A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Juvenile Rheumatoid Arthritis
Not yet reported Centocor, Inc. 123 participants Est. completion 2006-12Other conditions: Rheumatoid Arthritis, JuvenileView official trial listing → -
Completed NCT NCT00036387
A Study of the Safety and Effectiveness of Infliximab (Remicade) in Patients With Rheumatoid Arthritis.
Not yet reported Centocor, Inc. 347 participants Est. completion 2003-11Other conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00036868
Combination Chemotherapy With Trastuzumab in Treating Women With Metastatic Breast Cancer
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 90 participants Est. completion 2010-02 13 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00037102
Combination Therapy With Avonex and BiMonthly High Dose Intravenous Methotrexate in Multiple Sclerosis
Not yet reported MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute 16 participants Est. completion 2003-12Other conditions: Multiple SclerosisView official trial listing → -
Withdrawn NCT NCT00037115
Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event.
Not yet reported MidAmerica Neuroscience Research Foundation at Rowe Neurology Institute Est. completion 2002-12 1 siteOther conditions: Demyelinating Disorders, Multiple Sclerosis, Optic Neuritis, Myelitis, NeuritisView official trial listing → -
Completed NCT NCT00038298
A Rheumatoid Arthritis (RA) Study Treating Signs and Symptoms of RA in People With RA & Receiving Methotrexate
Not yet reported Amgen 53 participants Est. completion 2004-05Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00038610
Study of Hyper-CVAD Plus Imatinib Mesylate for Philadelphia-Positive Acute Lymphocytic Leukemia
Not yet reported M.D. Anderson Cancer Center 54 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00039130
Rituximab, Chemotherapy, and Filgrastim in Treating Patients With Burkitt's Lymphoma or Burkitt's Leukemia
Not yet reported Alliance for Clinical Trials in Oncology 105 participants Est. completion 2014-10 31 sites Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00039377
Chemotherapy, Imatinib Mesylate, and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 58 participants Est. completion 2014-02 97 sites Stand-aloneOther conditions: Adult Acute Lymphoblastic Leukemia in RemissionView official trial listing → -
Completed NCT NCT00040690
Combination Chemotherapy in Treating Patients With Burkitt's Lymphoma or Burkitt's Leukemia
Not yet reported Medical Research Council 120 participants Est. completion 2008-12 1 siteOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00041132
S0213 Chemotherapy Plus Rituximab in Treating Patients With Mantle Cell Lymphoma
Not yet reported SWOG Cancer Research Network 56 participants Est. completion 2011-06 Stand-aloneOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT00041288
Study Of Two Non-Myeloablative Stem Cell Transplant Strategies For Low-Grade Lymphoma And CLL
Not yet reported University of Texas Southwestern Medical Center 10 participants Est. completion 2003-01 23 sitesOther conditions: Leukemia, LymphomaView official trial listing → -
Status unknown NCT NCT00041613
Study to Compare the Overall Survival of Patients Receiving INGN 201 (Study Drug) With Patients Receiving Methotrexate
Not yet reported Introgen Therapeutics 5 sitesOther conditions: Carcinoma, Squamous CellView official trial listing → -
Terminated NCT NCT00042406
Trial With HuMax-CD4 in Participants With Rheumatoid Arthritis (RA) Failing Treatment With Methotrexate (MTX) and a TNF-alpha Blocker
Not yet reported, Not yet reported Genmab 83 participants Est. completion 2003-03-31 54 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00043732
Safety Study of SCIO-469 to Treat Patients With Active Rheumatoid Arthritis Receiving Methotrexate
Not yet reported Scios, Inc. 120 participants Est. completion 2003-09Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00045305
Reduced-Intensity Regimen Before Donor Bone Marrow Transplant in Treating Patients With Myelodysplastic Syndromes
Not yet reported Eastern Cooperative Oncology Group 17 participants Est. completion 2014-09 6 sites Stand-aloneOther conditions: Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00045539
Methotrexate and Thiotepa in Treating Patients With Newly Diagnosed Primary CNS Lymphoma
Not yet reported New Approaches to Brain Tumor Therapy Consortium Est. completion 2006-01 9 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00048542
Study of Human Anti-TNF Monoclonal Antibody Adalimumab in Children With Polyarticular Juvenile Idiopathic Arthritis (JIA)
Not yet reported Abbott 171 participants Est. completion 2010-06 31 sites Stand-aloneOther conditions: Arthritis, Juvenile IdiopathicView official trial listing → -
Completed NCT NCT00048568
A Phase III Study of Abatacept (BMS-188667) in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate
Not yet reported Bristol-Myers Squibb 1250 participants Est. completion 2009-10 48 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00049569
Combination Chemotherapy and Imatinib Mesylate in Treating Children With Relapsed Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 126 participants 1 site Stand-aloneOther conditions: L1 Childhood Acute Lymphoblastic Leukemia, L2 Childhood Acute Lymphoblastic Leukemia, Non-T, Non-B Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00049634
Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome, Acute Myeloid Leukemia, or Myeloproliferative Disorder
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 30 participants 2 sitesOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00051311
Modified Stem Cell Transplant Procedure to Treat Patients With Blood and Immune System Cancers
Not yet reported National Cancer Institute (NCI) 62 participants Est. completion 2014-09-25 1 site Stand-aloneOther conditions: Hematologic NeoplasmsView official trial listing → -
Completed NCT NCT00053196
Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Cancer
Not yet reported Alliance for Clinical Trials in Oncology 82 participants Est. completion 2010-08 12 sites Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma, Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00054340
Combination Chemotherapy and Antithymocyte Globulin in Reducing Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplantation For Myelodysplastic Syndrome or Myeloproliferative Disorder
Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2006-09 1 siteOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00057811
Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma
Not yet reported Children's Oncology Group 97 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Stage I Childhood Large Cell Lymphoma, Stage I Childhood Small Noncleaved Cell Lymphoma, Stage II Childhood Large Cell Lymphoma, Stage II Childhood Small Noncleaved Cell Lymphoma, Stage III Childhood Large Cell Lymphoma, Stage III Childhood Small Noncleaved Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma, Stage IV Childhood Small Noncleaved Cell Lymphoma, Untreated Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT00057954
Reduced-Intensity Regimen Before Allogeneic Transplant for Patients With Relapsed Non-Hodgkin's or Hodgkin's Lymphoma
Not yet reported Eastern Cooperative Oncology Group 6 participants Est. completion 2011-05 19 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT00058461
Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 82 participants 1 site Stand-aloneOther conditions: B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, L3 Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell LymphomaView official trial listing → -
Completed NCT NCT00059839
Comparison of Two Combination Chemotherapy Regimens With Either Vincristine or Vinblastine in Treating Patients With Advanced Anaplastic Large Cell Lymphoma
Not yet reported Children's Oncology Group 129 participants Est. completion 2014-07 159 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00061945
Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported National Cancer Institute (NCI) 302 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: Acute Undifferentiated Leukemia, B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, L1 Adult Acute Lymphoblastic Leukemia, L1 Childhood Acute Lymphoblastic Leukemia, L2 Adult Acute Lymphoblastic Leukemia, L2 Childhood Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia, Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia, Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia, T-cell Adult Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic Leukemia, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00068250
Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma
Not yet reported, Not yet reported Radiation Therapy Oncology Group 60 participants Est. completion 2016-12 26 sites Stand-aloneOther conditions: Brain and Central Nervous System Tumors, LymphomaView official trial listing → -
Completed NCT NCT00069017
Effects of MEDI-522 On Disease Activity and Progression of Joint Damage in Patients With Active Rheumatoid Arthritis Suboptimally Responding to Methotrexate
Not yet reported MedImmune LLC 300 participants Est. completion 2006-04 40 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00070135
Fludarabine and Busulfan Followed by Allogeneic Stem Cell Transplant in Treating Older Patients With Acute Myeloid Leukemia in First Complete Remission
Not yet reported Alliance for Clinical Trials in Oncology 121 participants Est. completion 2016-06-15 21 sites Stand-aloneOther conditions: Adult Acute Myeloid Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00070174
Gemtuzumab Ozogamicin in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia Undergoing Remission Induction and Intensification Therapy
Not yet reported Children's Oncology Group 350 participants Est. completion 2013-12 148 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00074178
Methotrexate, Cyclophosphamide, and Etoposide Phosphate Given With Osmotic Blood-Brain Barrier Disruption Plus Dexamethasone and Cytarabine in Treating Patients With Primary CNS Lymphoma
Not yet reported OHSU Knight Cancer Institute 22 participants Est. completion 2006-07 1 siteOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00074191
Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma
Not yet reported OHSU Knight Cancer Institute 1 participants Est. completion 2000-10 1 siteOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT00074269
Allogeneic Stem Cell Transplant After ATG, High-Dose Melphalan, and Fludarabine for Patients With Breast Cancer
Not yet reported University of California, San Diego 5 participants Est. completion 2008-03 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00074438
Study to Assess the Efficacy and Safety of Rituximab in Patients With Rheumatoid Arthritis
Not yet reported Genentech, Inc. 465 participants Est. completion 2011-07 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00075725
Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 3154 participants Est. completion 2021-03-31 234 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia, Childhood B Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT00076206
Study Evaluating CCI-779 in Active Rheumatoid Arthritis on Concomitant Methotrexate Therapy
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer Est. completion 2005-08Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00077870
A Study to Evaluate the Safety of Escalating Doses of Ocrelizumab in Subjects With Rheumatoid Arthritis
Not yet reported, Not yet reported Genentech, Inc. 237 participants Est. completion 2006-12Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00078793
Registry of Etanercept (Enbrel®) In Children With Juvenile Rheumatoid Arthritis
Amgen 600 participants Est. completion 2008-01Other conditions: Juvenile Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT00081055
OTI-010 for Graft-Versus-Host Disease Prophylaxis in Treating Patients Who Are Undergoing Donor Peripheral Stem Cell Transplantation for Hematologic Malignancies
Not yet reported Mesoblast International Sàrl 1 siteOther conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00082797
High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Not yet reported Eastern Cooperative Oncology Group 36 participants 65 sitesOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00083031
Metronomic Low-Dose Cyclophosphamide and Methotrexate With or Without Bevacizumab in Treating Women With Metastatic Breast Cancer
Not yet reported Dana-Farber Cancer Institute 57 participants Est. completion 2009-08 4 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT00083759
Natalizumab in the Treatment of Rheumatoid Arthritis in Subjects Receiving Methotrexate
Not yet reported Biogen 299 participants 12 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00084838
Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RT
Not yet reported Dana-Farber Cancer Institute 25 participants Est. completion 2013-03 12 sites Stand-aloneOther conditions: Central Nervous System Tumor, PediatricView official trial listing → -
Completed NCT NCT00089037
Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation
Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2005-04 1 siteOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00089349
Alemtuzumab With or Without Methotrexate and Mercaptopurine in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 25 participants 1 site Stand-aloneOther conditions: Recurrent Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00095147
Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 431 participants Est. completion 2009-07 76 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00095342
Study Evaluating TMI-005 in Active Rheumatoid Arthritis
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 390 participants Est. completion 2005-08 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00095498
Efficacy, Safety and Tolerability of Denosumab in the Treatment of Rheumatoid Arthritis
Not yet reported Amgen 227 participants Est. completion 2007-04-01Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00096135
Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or Testes
Not yet reported Children's Oncology Group 168 participants 153 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00096460
Autologous or Donor Stem Cell Transplantation in Treating Patients With Recurrent Non-Hodgkin's Lymphoma (BMT CTN 0202)
Not yet reported, Not yet reported Medical College of Wisconsin 30 participants Est. completion 2009-03 30 sitesOther conditions: Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Follicular LymphomaView official trial listing → -
Completed NCT NCT00098774
Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Primary CNS Lymphoma
Not yet reported Alliance for Clinical Trials in Oncology 47 participants Est. completion 2014-09 30 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00098839
Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL)
Not yet reported, Not yet reported Children's Oncology Group 134 participants Est. completion 2011-04 46 sites Stand-aloneOther conditions: Recurrent Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00101101
Universal Granulocyte Macrophage-colony Stimulating Factor (GM-CSF)-Producing and GM.CD40L for Autologous Tumor Vaccine in Mantle Cell Lymphoma
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 43 participants Est. completion 2021-06-14 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00103285
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 5377 participants Est. completion 2021-03-31 236 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Childhood B Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00105976
Efficacy Study of MM-093 in Rheumatoid Arthritis Patients on Methotrexate (MTX)
Not yet reported Merrimack Pharmaceuticals 260 participants 38 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00106522
A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis Currently on Methotrexate Therapy
Not yet reported Hoffmann-La Roche 499 participants Est. completion 2007-11 168 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00106535
A Study to Assess the Effect of Tocilizumab + Methotrexate on Prevention of Structural Joint Damage in Patients With Moderate to Severe Active Rheumatoid Arthritis (RA)
Not yet reported Hoffmann-La Roche 1196 participants Est. completion 2012-07 152 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00106548
A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 623 participants Est. completion 2007-10 74 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00109408
A Study to Assess the Safety and Efficacy of Tocilizumab in Patients With Active Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 673 participants Est. completion 2007-12 147 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00109837
S0333 Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported SWOG Cancer Research Network 79 participants Est. completion 2014-11 78 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00112034
AVONEX® Combination Trial - "ACT"
Not yet reported Biogen 350 participants Est. completion 2007-05 1 siteOther conditions: Multiple Sclerosis, Relapsing-RemittingView official trial listing → -
Completed NCT NCT00112645
Donor Stem Cell Transplant in Treating Young Patients With Relapsed or Refractory Solid Tumors
Not yet reported Milton S. Hershey Medical Center 10 participants Est. completion 2011-02 1 siteOther conditions: Neuroblastoma, Sarcoma, Unspecified Childhood Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00115219
Evaluating Efficacy and Safety of Etanercept 50 mg Twice Weekly (BIW) in Rheumatoid Arthritis (RA) Subjects Who Are Sub-Optimal Responders to Etanercept 50 mg Once Weekly (QW)
Not yet reported Amgen 200 participantsOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00119301
Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma
Not yet reported Memorial Sloan Kettering Cancer Center 18 participants 1 siteOther conditions: SarcomaView official trial listing → -
Completed NCT NCT00121134
Bevacizumab With or Without Cyclophosphamide and Methotrexate: A Pilot Study in Women With Operable Breast Cancer
Not yet reported Harold J. Burstein, MD, PhD 164 participants Est. completion 2011-05 5 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00122382
Remission and Joint Damage Progression in Early Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 1052 participants Est. completion 2009-02 89 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00124111
A Study of Cyclophosphamide/Methotrexate/5-Fluorouracil (CMF) With Pegfilgrastim in Subjects With Breast Cancer
Not yet reported AmgenOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00124982
Study of Abatacept (BMS-188667) in Subjects With Active Rheumatoid Arthritis on Background Non-biologic DMARDS (Disease Modifying Antirheumatic Drugs) Who Have an Inadequate Response to Anti-TNF Therapy
Not yet reported Bristol-Myers Squibb 1286 participants Est. completion 2009-08 148 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00126191
Intensive Chemotherapy and Rituximab in the Treatment of Burkitt Lymphoma
Not yet reported Dana-Farber Cancer Institute 10 participants Est. completion 2011-06 2 sites Stand-aloneOther conditions: Burkitt Lymphoma, Non-Hodgkins Lymphoma, Atypical Burkitt LymphomaView official trial listing → -
Completed NCT NCT00129506
Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion
Not yet reported Wiebe, Ellen, M.D. 300 participants Est. completion 2005-10 1 siteOther conditions: Unwanted PregnanciesView official trial listing → -
Completed NCT NCT00130195
Study of Imatinib-Combined Chemotherapy for BCR-ABL-Positive Acute Lymphoblastic Leukemia (ALL)
Not yet reported Japan Adult Leukemia Study Group 100 participants Est. completion 2008-05 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT00131027
High-Dose Methotrexate (MTX) for Adult Acute Lymphoblastic Leukemia (ALL)
Not yet reported Japan Adult Leukemia Study Group 240 participants Est. completion 2011-09 1 site Stand-aloneOther conditions: Lymphoblastic Leukemia, AcuteView official trial listing → -
Status unknown NCT NCT00131053
Applying Pediatric Regimens to Younger Adult Patients With Acute Lymphoblastic Leukemia (ALL)
Not yet reported Japan Adult Leukemia Study Group 120 participants Est. completion 2011-09 1 site Stand-aloneOther conditions: Lymphoblastic Leukemia, AcuteView official trial listing → -
Completed NCT NCT00132691
Multicenter Uveitis Steroid Treatment (MUST) Trial
Not yet reported JHSPH Center for Clinical Trials 255 participants Est. completion 2010-12 23 sitesOther conditions: UveitisView official trial listing → -
Completed NCT NCT00132899
COMMIT (Combination Of Maintenance Methotrexate-Infliximab Trial)
Not yet reported University of Western Ontario, Canada 128 participants Est. completion 2008-07 1 siteOther conditions: Crohn's DiseaseView official trial listing → -
Completed NCT NCT00133991
Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or Leukemia
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 23 participants Est. completion 2013-08 2 sites Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00134030
Combination Chemotherapy, PEG-Interferon Alfa-2b, and Surgery in Treating Patients With Osteosarcoma
Not yet reported Children's Oncology Group 1334 participants Est. completion 2022-09-30 218 sites Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT00136084
Treatment of Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplasia
Not yet reported St. Jude Children's Research Hospital 238 participants Est. completion 2012-06 8 sites Stand-aloneOther conditions: Leukemia, Myelocytic, AcuteView official trial listing → -
Completed NCT NCT00136435
A Study in Adults With Untreated Acute Lymphoblastic Leukemia
Not yet reported Dana-Farber Cancer Institute 100 participants Est. completion 2011-05 12 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00137111
Therapy for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
Not yet reported St. Jude Children's Research Hospital 501 participants Est. completion 2014-04 2 sitesOther conditions: Lymphoblastic Leukemia, AcuteView official trial listing → -
Status unknown NCT NCT00137982
Evaluation of Therapeutic Strategies for Treatment of Ectopic Pregnancies (EP) and Evaluation of Subsequent Fertility
Not yet reported Hopital Antoine Beclere 600 participants Est. completion 2008-07 18 sitesOther conditions: Tubal PregnancyView official trial listing → -
Completed NCT NCT00141830
Study Evaluating ERB-041 With Methotrexate in Rheumatoid Arthritis
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 159 participants Est. completion 2006-10-19 35 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00141934
A Multicentre Trial to Determine the Efficacy of AD 452 in RA Subjects.
Not yet reported Sosei 232 participants 10 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00143845
Study of Low-Intensity Conditioning for Allogeneic Stem Cell Transplant
Not yet reported University of Michigan Rogel Cancer Center 54 participants Est. completion 2013-02 1 site Stand-aloneOther conditions: Multiple Myeloma, Lymphocytic Leukemia, Chronic, Lymphoma, Low-GradeView official trial listing → -
Completed NCT NCT00146614
Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation
Not yet reported Dana-Farber Cancer Institute 105 participants Est. completion 2003-04 3 sitesOther conditions: Graft Versus Host Disease, Hematologic MalignanciesView official trial listing → -
Completed NCT NCT00147966
Assessment of Rituximab's Immunomodulatory Synovial Effects (The ARISE Study)
Not yet reported University of California, San Diego 24 participants Est. completion 2009-12 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00152139
Stem Cell Transplantation for Patients With Hematologic Malignancies
Not yet reported St. Jude Children's Research Hospital 33 participants Est. completion 2009-01 1 siteOther conditions: Acute Lymphoblastic Leukemias, Acute Myelocytic Leukemia, Chronic Myeloid Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndrome, Hemoglobinuria, Paroxysmal, Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT00152178
The Comparative Trial of UFT + TAM With CMF + TAM in Adjuvant Therapy for Breast Cancer (CUBC)
Not yet reported Taiho Pharmaceutical Co., Ltd. 680 participants Est. completion 2008-08 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00152191
A Randomized Controlled Study of Postoperative Adjuvant Therapy of Uracil-tegafur (UFT) Compared With Cyclophosphamide/Methotrexate/5-fluorouracil (CMF) in Breast Cancer (NSAS-BC)
Not yet reported Taiho Pharmaceutical Co., Ltd. 1300 participants Est. completion 2008-01 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00152386
A Placebo Controlled Study to Assess Efficacy and Safety of Certolizumab Pegol in the Treatment of Rheumatoid Arthritis
Not yet reported UCB Pharma 950 participants Est. completion 2006-10 76 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00153530
Whole Brain Irradiation in Primary Central Nervous System (CNS) Lymphoma (PCNSL)
Not yet reported Charite University, Berlin, Germany 604 participants Est. completion 2009-05 1 site Stand-aloneOther conditions: Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT00154336
A Study of Imatinib 400 mg Once Daily in Combination With Methotrexate in the Treatment of Rheumatoid Arthritis.
Not yet reported Novartis Pharmaceuticals 50 participants Est. completion 2005-08 15 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00160602
A Study of Liquid Certolizumab Pegol as Additional Medication to Methotrexate in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis
Not yet reported UCB Pharma 590 participants Est. completion 2006-09 70 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00160641
A Study of the Safety and Effectiveness of Liquid Certolizumab Pegol in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis
Not yet reported UCB Pharma 567 participants Est. completion 2012-02 67 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00161239
LAMPP Trial for Peripheral and Cutaneous T-Cell Lymphoma
Not yet reported University of Medicine and Dentistry of New Jersey 64 participants Est. completion 2007-10 1 siteOther conditions: T-Cell LymphomaView official trial listing → -
Completed NCT NCT00161655
Study Evaluating Etanercept and Methotrexate in Plaque Psoriasis
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 60 participants Est. completion 2006-12 8 sitesOther conditions: Psoriasis, Arthritis, PsoriaticView official trial listing → -
Completed NCT NCT00162266
Abatacept With Methotrexate- Phase IIB
Not yet reported Bristol-Myers Squibb 524 participants Est. completion 2009-09 57 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00162292
Multiple Ascending Dose Study of BMS-582949 in Patients With Stable Rheumatoid Arthritis on the Methotrexate Background
Not yet reported Bristol-Myers Squibb 33 participants Est. completion 2007-10 10 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00165178
Treatment of Acute Lymphoblastic Leukemia in Children
Not yet reported Dana-Farber Cancer Institute 498 participants Est. completion 2011-05 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00174655
BIG 02/98 Docetaxel - Breast Cancer
Not yet reported Sanofi 2887 participants Est. completion 2011-09 21 sitesOther conditions: Breast NeoplasmsView official trial listing → -
Completed NCT NCT00174707
Study of Docetaxel in Breast Cancer Patients
Not yet reported Sanofi 998 participants Est. completion 2007-12 1 site Stand-aloneOther conditions: Breast NeoplasmsView official trial listing → -
Completed NCT NCT00175877
A Study of the Safety and Effectiveness of Lyophilized Certolizumab Pegol in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis
Not yet reported UCB Pharma 857 participants Est. completion 2012-02 121 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00176462
CINJALL: Treatment for Children With Acute Lymphocytic Leukemia
Not yet reported Rutgers, The State University of New Jersey 60 participants Est. completion 2008-09 2 sites Stand-aloneOther conditions: Acute Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT00176553
A Pilot Study of Dextromethorphan for the Prevention and Treatment of Methotrexate Neurotoxicity
Not yet reported University of Medicine and Dentistry of New Jersey 20 participants Est. completion 2007-05 1 siteOther conditions: Neurotoxicity SyndromesView official trial listing → -
Completed NCT NCT00180908
Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 226 participants 1 siteObstructive sleep apneaView official trial listing → -
Completed NCT NCT00184886
The Influence of Methotrexate on the Metabolism and Vascular Effects of Adenosine in Humans
Not yet reported Radboud University Medical Center 10 participants Est. completion 2005-01 1 siteOther conditions: Methotrexate, VasodilationView official trial listing → -
Completed NCT NCT00186810
Stem Cell Transplantation With Identical Donors for Patients With Sickle Cell Disease
Not yet reported St. Jude Children's Research Hospital 15 participants Est. completion 2007-10 1 siteOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT00186875
Therapy for Pediatric Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported St. Jude Children's Research Hospital 47 participants Est. completion 2016-08 2 sitesOther conditions: Acute Lymphoblastic Leukemia, Lymphoma, LymphoblasticView official trial listing → -
Terminated NCT NCT00187005
Total Therapy Study XIV for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
Not yet reported St. Jude Children's Research Hospital 53 participants Est. completion 2002-07 1 siteOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00187057
Study for Treatment of Cancer in Children With Ataxia-telangiectasia
Not yet reported St. Jude Children's Research Hospital 6 participants Est. completion 2013-06 1 siteOther conditions: Ataxia-TelangiectasiaView official trial listing → -
Completed NCT NCT00187070
Large Cell Lymphoma Pilot Study III
Not yet reported St. Jude Children's Research Hospital 8 participants Est. completion 2001-07 1 siteOther conditions: Lymphoma, Large Cell, Lymphoma, Non-HodgkinView official trial listing → -
Completed NCT NCT00187083
A Study of Children With Refractory or Relapsed ALL
Not yet reported St. Jude Children's Research Hospital 40 participants Est. completion 2003-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00187122
Treatment for Patients With Stage III or IV Non-Hodgkin Lymphoma
Not yet reported St. Jude Children's Research Hospital 42 participants Est. completion 2004-06 1 siteOther conditions: Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT00187161
Treatment of Burkitt Lymphoma/Leukemia and B Large Cell NHL
Not yet reported St. Jude Children's Research Hospital 68 participants Est. completion 2007-01 1 site Stand-aloneOther conditions: Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, Mature B-CellView official trial listing → -
Completed NCT NCT00189488
Trial to Evaluate Palifermin in the Reduction of Acute Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Allogeneic Marrow/Peripheral Blood Progenitor Cell (PBPC) Transplantation
Not yet reported Swedish Orphan Biovitrum 155 participants Est. completion 2013-08 Stand-aloneOther conditions: Graft Versus Host Disease, Hematologic MalignanciesView official trial listing → -
Terminated NCT NCT00189878
A Study of the Use of Methotrexate in the Treatment of Chronic Idiopathic Urticaria
Not yet reported Barnsley Hospital 3 participants Est. completion 2008-08Other conditions: UrticariaView official trial listing → -
Completed NCT NCT00193973
Idarubicin Based Combined Modality Therapy in Primary CNS Lymphoma
Not yet reported Trans Tasman Radiation Oncology Group 20 participants Est. completion 2013-08 15 sitesOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT00194272
Two-Dose Methotrexate for Ectopic Pregnancy
Not yet reported University of Pennsylvania 100 participants Est. completion 2007-06 3 sitesOther conditions: Ectopic PregnancyView official trial listing → -
Completed NCT NCT00194779
Combination Chemotherapy and Filgrastim Before Surgery in Treating Patients With HER2-Positive Breast Cancer That Can Be Removed By Surgery
Not yet reported University of Washington 50 participants Est. completion 2011-06 1 site Stand-aloneOther conditions: Estrogen Receptor-negative Breast Cancer, Estrogen Receptor-positive Breast Cancer, HER2-positive Breast Cancer, Progesterone Receptor-negative Breast Cancer, Progesterone Receptor-positive Breast Cancer, Stage IA Breast Cancer, Stage IB Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast CancerView official trial listing → -
Terminated NCT NCT00194792
Hormone Therapy and Combination Chemotherapy Before and After Surgery in Treating Patients With Stage I-IIIA Breast Cancer
Not yet reported University of Washington 28 participants Est. completion 2011-07 1 site Stand-aloneOther conditions: Estrogen Receptor-positive Breast Cancer, HER2-negative Breast Cancer, Progesterone Receptor-positive Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast CancerView official trial listing → -
Completed NCT NCT00195494
Study Comparing Etanercept and Methotrexate vs. Methotrexate Alone in Rheumatoid Arthritis
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 542 participants Est. completion 2008-03 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00195663
Efficacy and Safety of Adalimumab and Methotrexate (MTX) Versus MTX Monotherapy in Subjects With Early Rheumatoid Arthritis
Not yet reported AbbVie (prior sponsor, Abbott) 799 participants Est. completion 2012-04 123 sites Stand-aloneOther conditions: Early Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00195702
Efficacy and Safety of Adalimumab in Patients With Active Rheumatoid Arthritis Treated Concomitantly With Methotrexate.
Not yet reported Abbott 619 participants Est. completion 2010-08 87 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00195871
Safety and Efficacy of an Adult Acute Lymphoblastic Leukemia Chemotherapy for Adult Lymphoblastic Lymphoma
Not yet reported Centre Henri Becquerel 155 participants Est. completion 2015-12 19 sitesOther conditions: Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT00198978
German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Goethe University 377 participants Est. completion 2014-06 1 site Stand-aloneOther conditions: Adult Acute Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00198991
German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)
Not yet reported Goethe University 1883 participants Est. completion 2013-06-30 1 site Stand-aloneOther conditions: Adult Acute Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00199004
Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab
Not yet reported Johann Wolfgang Goethe University Hospital 60 participants Est. completion 2009-03 1 siteOther conditions: Adult Acute Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00199017
German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adults
Not yet reported Johann Wolfgang Goethe University Hospital 75 participants 1 siteOther conditions: Lymphoma, LymphoblasticView official trial listing → -
Completed NCT NCT00199056
German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99)
Not yet reported Goethe University 225 participants Est. completion 2005-12 1 siteOther conditions: Adult Acute Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00199069
German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93)
Not yet reported Goethe University 720 participants Est. completion 2001-05 1 siteOther conditions: Adult Acute Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00199082
Newly Diagnosed Mature B-ALL, Burkitt's Lymphoma and Other High-grade Lymphoma in Adults
Not yet reported Nicola Goekbuget 650 participants Est. completion 2010-06 1 site Stand-aloneOther conditions: Burkitt's Lymphoma, Burkitt's Leukemia, Mediastinal Neoplasms, Lymphoblastic Lymphoma, Large Cell Anaplastic LymphomaView official trial listing → -
Completed NCT NCT00199095
Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia
Not yet reported Goethe University 40 participants Est. completion 2003-06 1 siteOther conditions: Adult Acute Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT00199186
Study Comparing Imatinib With Chemotherapy as Induction in Elderly Patients With Philadelphia Positive Acute Lymphoblastic Leukemia (ALL)
Not yet reported Johann Wolfgang Goethe University Hospital 1 siteOther conditions: Philadelphia Positive Acute Lymphoblastic Leukemia, Lymphoid Blastic Phase of Chronic Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00202852
A Placebo-Controlled, Double-Blinded, Randomized Trial of Remicade in Korean Patients With Rheumatoid Arthritis Despite Methotrexate (Study P04280)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 143 participants Est. completion 2006-03-01Other conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00206219
Head and Neck Phase III Iressa Versus Methotrexate Refractory: Iressa Versus Methotrexate (IMEX)
Not yet reported AstraZeneca 477 participants Est. completion 2007-09 109 sitesOther conditions: Squamous Cell Carcinoma of the Head and NeckView official trial listing → -
Completed NCT NCT00207714
An Efficacy and Safety Study of CNTO 148 Subcutaneous Injection Compared With Placebo in Patients With Active Rheumatoid Arthritis
Not yet reported Centocor, Inc. 172 participants Est. completion 2006-02 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00209859
Methotrexate and Cyclosporine in Treatment of Early Rheumatoid Arthritis
Not yet reported Hvidovre University Hospital 160 participants Est. completion 2007-11 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00210314
Phase II Trial of Combined Modality Treatment in Primary Central Nervous System Lymphoma
Not yet reported International Extranodal Lymphoma Study Group (IELSG) 79 participants Est. completion 2007-12 1 site Stand-aloneOther conditions: Lymphoma, B CellView official trial listing → -
Completed NCT NCT00210379
Phase II Study of Combined Modality Treatment in Primary Testicular Non-Hodgkin's Lymphoma
Not yet reported International Extranodal Lymphoma Study Group (IELSG) 64 participants Est. completion 2007-03 1 siteOther conditions: Lymphoma, B CellView official trial listing → -
Completed NCT NCT00213538
Gene Expression Profiling in PBMCs as a Tool for Prediction of Anakinra Responsiveness in Rheumatoid Arthritis
University Hospital, Rouen 341 participants Est. completion 2016-12 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00215046
Vinblastine and Methotrexate in Children With Pulmonary Vein Stenosis
Not yet reported Boston Children's Hospital 28 participants Est. completion 2006-10 2 sites Stand-aloneOther conditions: Intraluminal Pulmonary Vein StenosisView official trial listing → -
Completed NCT NCT00219791
Study of Glucarpidase (CPG2) for the Management of Patients With Delayed Methotrexate Clearance
Not yet reported BTG International Inc. Est. completion 2003-06 1 siteOther conditions: NeoplasmsView official trial listing → -
Completed NCT NCT00221325
A Safety Study of Rituximab Plus MTX Injected Into the Cerebrospinal Fluid in the Treatment of Brain Lymphoma
Not yet reported University of California, San Francisco 14 participants Est. completion 2013-03 4 sites Stand-aloneOther conditions: Central Nervous System Lymphoma, Intraocular LymphomaView official trial listing → -
Status unknown NCT NCT00222612
Medical Research Council (MRC) Working Party on Leukaemia in Children UK National Acute Lymphoblastic Leukaemia (ALL) Trial: UKALL 2003
Not yet reported University of Oxford 2100 participants Est. completion 2013-08 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Withdrawn NCT NCT00230035
Lupus Immunosuppressive/Immunomodulatory Therapy or Stem Cell Transplant (LIST)
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 5 sitesOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Terminated NCT NCT00233558
Open-Label Steroid Reduction Study of Adalimumab With Methotrexate in Patients With Active Rheumatoid Arthritis
Not yet reported Abbott 160 participants 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00234845
Adalimumab in Combination With Methotrexate vs Methotrexate Alone in Early Rheumatoid Arthritis
Not yet reported Abbott 148 participants 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00234936
Quality of Life Study With Adalimumab in Rheumatoid Arthritis
Not yet reported Abbott 200 participantsOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00235820
Safety and Efficacy of Adalimumab to Methotrexate and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis
Not yet reported Abbott 271 participants 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT00235859
Adalimumab Administered in Korean Rheumatoid Arthritis Subjects Treated With Methotrexate
Not yet reported Abbott 128 participantsOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00236028
A Safety and Efficacy Study for Infliximab (Remicade) With Methotrexate in Patients With Early Rheumatoid Arthritis
Not yet reported Centocor, Inc. 607 participants Est. completion 2003-04Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00241189
Rapamycin vs Methotrexate in Diffuse SSc
Not yet reported, Not yet reported University of California, Los Angeles 17 participants Est. completion 2006-06 1 siteOther conditions: Systemic SclerosisView official trial listing → -
Completed NCT NCT00243412
A Study of the Safety and Efficacy of Rituximab in Patients With Moderate to Severe Rheumatoid Arthritis Receiving Methotrexate
Not yet reported Genentech, Inc. 42 participants Est. completion 2009-02 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00243750
Methotrexate in Ankylosing Spondylitis (MTX in AS)
Not yet reported Charite University, Berlin, Germany 20 participants Est. completion 2005-11 1 siteOther conditions: Ankylosing SpondylitisView official trial listing → -
Completed NCT NCT00244556
Study Comparing Enbrel (Etanercept) Plus Methotrexate Versus Enbrel Alone in Active Rheumatoid Arthritis Despite Current Methotrexate Therapy
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 300 participants Est. completion 2004-05Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00245037
Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer
Not yet reported, Not yet reported OHSU Knight Cancer Institute 147 participants Est. completion 2015-08 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous ConditionView official trial listing → -
Completed NCT NCT00246064
The Infliximab Rheumatoid Arthritis Methotrexate Tapering (iRAMT) Protocol
Not yet reported Centocor Ortho Biotech Services, L.L.C. 210 participants Est. completion 2003-11Other conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00249808
A Study of Efalizumab in Participants With Moderate to Severe Chronic Psoriasis Who Have Failed, Have a Contraindication to, or Are Intolerant of Other Systemic Therapies
Not yet reported Merck KGaA, Darmstadt, Germany 1266 participants Est. completion 2007-01-25 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT00251641
The Effects of Infliximab Versus Methotrexate in the Treatment of Moderate to Severe Psoriasis (Study P04271AM2)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 868 participants Est. completion 2008-06-01Other conditions: PsoriasisView official trial listing → -
Completed NCT NCT00252668
Study Evaluating the Combination of Etanercept and Methotrexate in Rheumatoid Arthritis Subjects
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 300 participants Est. completion 2005-09Other conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00253552
G-CSF-Treated Donor Bone Marrow Transplant in Treating Patients With Hematologic Disorders
Not yet reported OHSU Knight Cancer Institute 4 participants Est. completion 2006-05 1 siteOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, SarcomaView official trial listing → -
Completed NCT NCT00254982
Infliximab in High Need Versus Low Need Psoriasis Patients: The IHELP Study (Study P04320)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 593 participants Est. completion 2006-09 Stand-aloneOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT00259610
Treatment of Early Aggressive Rheumatoid Arthritis (TEAR)
Not yet reported University of Alabama at Birmingham 755 participants Est. completion 2009-06 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00262925
Combination Chemotherapy and Alemtuzumab in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2013-02 58 sites Stand-aloneOther conditions: Recurrent Adult Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00264537
A Study of the Safety and Efficacy of Golimumab in Subjects With Rheumatoid Arthritis That Are Methotrexate-naive
Not yet reported Centocor, Inc. 637 participants Est. completion 2012-06 75 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00264550
An Efficacy and Safety Study of Golimumab in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Centocor, Inc. 444 participants Est. completion 2012-05 50 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00266227
A Study of Retreatment With Rituximab in Patients With Rheumatoid Arthritis Receiving Background Methotrexate
Not yet reported Genentech, Inc. 559 participants Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00267865
Chemotherapy and HAART to Treat AIDS-related Primary Brain Lymphoma
Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2019-09-19 1 site Stand-aloneOther conditions: AIDS-Related-Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT00268528
Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission
Children's Oncology Group 720 participants Est. completion 2020-06-30 135 sitesOther conditions: Childhood Acute Lymphoblastic Leukemia in RemissionView official trial listing → -
Completed NCT NCT00269867
Infliximab Plus Methotrexate for the Treatment of Rheumatoid Arthritis
Not yet reported Centocor, Inc. 428 participants Est. completion 2000-03Other conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00275106
Prednisolone or Dexamethasone Combined With Chemotherapy in Treating Young Patients With Newly Diagnosed Lymphoblastic Lymphoma
Not yet reported Children's Cancer and Leukaemia Group 600 participants Est. completion 2012-08 22 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00276601
Combination Chemotherapy in Treating Patients With Acute Promyelocytic Leukemia
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Est. completion 2013-06 7 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00276757
Combination Chemotherapy in Treating Young Patients With Langerhans Cell Histiocytosis
Not yet reported Histiocyte Society 376 participants Est. completion 2013-06 33 sitesOther conditions: Childhood Langerhans Cell HistiocytosisView official trial listing → -
Terminated NCT NCT00278265
Methotrexate Followed by Fludarabine in Patients With T-Cell Large Granular Lymphocytic Leukemia
Not yet reported German CLL Study Group 12 participants Est. completion 2009-12 7 sitesOther conditions: T-Cell Large Granular Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT00278278
Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Newly Diagnosed Gliomas
Not yet reported German Society for Pediatric Oncology and Hematology GPOH gGmbH 150 participants 1 site Stand-aloneOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00280917
Oral CF101 and Methotrexate Treatment in Rheumatoid Arthritis Patients
Not yet reported Can-Fite BioPharma 254 participants Est. completion 2007-04 35 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00281879
Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer
Not yet reported OHSU Knight Cancer Institute 200 participants Est. completion 2008-03 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Unusual Cancers of ChildhoodView official trial listing → -
Status unknown NCT NCT00281905
Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors
Not yet reported Children's Cancer and Leukaemia Group 50 participants 21 sitesOther conditions: Brain and Central Nervous System Tumors, NeuroblastomaView official trial listing → -
Completed NCT NCT00281983
Fludarabine and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Lymphocytic Leukemia or Waldenstrom's Macroglobulinemia
Not yet reported, Not yet reported German CLL Study Group 100 participants Est. completion 2010-07 13 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00282308
A Study to Evaluate the Effects of Rituximab on Immune Responses in Subjects With Active Rheumatoid Arthritis Receiving Background Methotrexate
Not yet reported Genentech, Inc. 103 participants Est. completion 2012-05-28 34 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00283985
Association of L-asparaginase-Methotrexate-Dexamethasone for Nasal and Nasal-type Natural Killer (NK)-T-cell Lymphoma
Not yet reported University Hospital, Limoges 40 participants Est. completion 2012-06 25 sitesOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Status unknown NCT NCT00287924
High-Dose Methotrexate in Treating Young Patients With Residual Ependymoma
Not yet reported Children's Cancer and Leukaemia Group 29 participants 21 sitesOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00290433
Efficacy of the HCVIDDOXIL Regimen in Patients With Newly Diagnosed Peripheral T-Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 55 participants Est. completion 2015-07 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00290498
Study of Rituximab-HCVAD Alternating With Rituximab-Methotrexate-Cytarabine Versus Standard Rituximab-CHOP Every 21 Days for Patients With Newly Diagnosed High Risk Aggressive B-Cell Non-Hodgkin's Lymphomas in Patients 60 Years Old or Younger
Not yet reported M.D. Anderson Cancer Center 67 participants Est. completion 2017-08-11 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Status unknown NCT NCT00291915
Multicenter Randomized Prospective Trial Comparing Methotrexate Alone or in Combination With Adalimumab in Early Arthritis
Not yet reported Goupe d'Etudes et de Recherche Clinique En Rhumatologie 80 participants Est. completion 2007-03 1 siteOther conditions: Rheumatoid Arthritis, ArthritisView official trial listing → -
Completed NCT NCT00292422
Dose-Escalating Study of BG9924 in Combination With Methotrexate in Active Rheumatoid Arthritis
Not yet reported Biogen 50 participants Est. completion 2007-05 10 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00293475
Methotrexate, Mannitol, Rituximab, and Carboplatin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
Not yet reported, Not yet reported OHSU Knight Cancer Institute 81 participants Est. completion 2023-01-31 4 sites Stand-aloneOther conditions: Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT00293826
A Multiple Dose Study to Evaluate Subcutaneous AMG 108 in Subjects With Rheumatoid Arthritis
Not yet reported Amgen 813 participants Est. completion 2008-02Other conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00295997
Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, or Aplastic Anemia
Not yet reported University of California, San Francisco 35 participants 2 sitesOther conditions: Chronic Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Terminated NCT NCT00296010
Liposomal Doxorubicin Compared With Observation or Cyclophosphamide and Methotrexate in Treating Older Women Who Have Undergone Surgery for Breast Cancer
Not yet reported ETOP IBCSG Partners Foundation 77 participants Est. completion 2011-12 33 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00296023
Donor Stem Cell Transplant in Treating Older or Frail Patients With Hematologic Cancer
Not yet reported University of California, San Francisco 25 participants Est. completion 2008-06 2 sites Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00296257
Assessment of Safety, Pharmacokinetics and Efficacy in a Combination Treatment With SMP-114
Not yet reported Dainippon Sumitomo Pharma Europe LTd. 312 participants Est. completion 2008-04 46 sitesOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Withdrawn NCT NCT00298012
Methotrexate in the Treatment of Axial Spondyloarthritis
Not yet reported Rheumatism Foundation Hospital 120 participants 5 sitesOther conditions: Spondylarthropathies, Spondylitis, AnkylosingView official trial listing → -
Terminated NCT NCT00298272
Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis
Not yet reported Biogen 54 participants Est. completion 2011-07 18 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00299104
A Study to Evaluate Rituximab in Combination With Methotrexate in Methotrexate-Naive Patients With Active Rheumatoid Arthritis
Not yet reported Genentech, Inc. 755 participants Est. completion 2013-07 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00299130
A Study to Evaluate the Safety and Efficacy of Rituximab in Combination With Methotrexate Compared to Methotrexate Alone in Patients With Active Rheumatoid Arthritis
Not yet reported Genentech, Inc. 511 participants Est. completion 2013-07 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00299182
Study of AMG 531 to Evaluate the Safety & Efficacy in Patients With Non-Hodgkin's Lymphoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 50 participants Est. completion 2012-04 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00301834
Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Patients With Hematologic Disorders
Not yet reported University of California, San Francisco 35 participants Est. completion 2011-09 2 sites Stand-aloneOther conditions: Congenital Amegakaryocytic Thrombocytopenia, Diamond-blackfan Anemia, Leukemia, Myelodysplastic Syndromes, Severe Congenital NeutropeniaView official trial listing → -
Terminated NCT NCT00301860
Donor Stem Cell Transplant Followed By Donor White Blood Cell Infusions in Treating Young Patients With Hematologic Cancer
Not yet reported University of California, San Francisco 8 participants Est. completion 2007-11 1 siteOther conditions: Leukemia, LymphomaView official trial listing → -
Withdrawn NCT NCT00301912
Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer
Not yet reported University of California, San Francisco 1 siteOther conditions: Anemia, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Status unknown NCT NCT00301925
Combination Chemotherapy in Treating Patients With Early Stage Breast Cancer That Has Been Removed By Surgery
Not yet reported Institute of Cancer Research, United Kingdom 4400 participants Est. completion 2024-09 152 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00303563
A Study of P38 Inhibitor (4) Monotherapy in Patients With Active Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 204 participants Est. completion 2007-12 61 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00303810
Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Ependymoma
Not yet reported Universitätsklinikum Hamburg-Eppendorf 567 participants 1 siteOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00307671
Treatment of Necrotizing Vasculitides for Patients Older Than 65 Years
Not yet reported Assistance Publique - Hôpitaux de Paris 108 participants Est. completion 2011-07 1 site Stand-aloneObstructive sleep apnea Other conditions: Vasculitis, Wegener's Granulomatosis, Microscopic Polyangiitis, Churg-Strauss SyndromeView official trial listing → -
Completed NCT NCT00308282
A Multi-Site Study to Evaluate the Safety and Effect of Study Drug on Participants With Rheumatoid Arthritis
Not yet reported Eli Lilly and Company 136 participants Est. completion 2007-10-18 14 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00309478
Randomized Study Comparing CMF and Goserelin + Tamoxifen in Premenopausal Receptor-positive Patients
Not yet reported Austrian Breast & Colorectal Cancer Study Group 1099 participants Est. completion 2004-06 Stand-aloneOther conditions: Early-stage Breast CancerView official trial listing → -
Completed NCT NCT00309569
Randomized Study Comparing Pre- and Postoperative vs. Conventional Adjuvant Treatment in Receptor-negative Patients
Not yet reported Austrian Breast & Colorectal Cancer Study Group 429 participants Est. completion 2000-09 Stand-aloneOther conditions: Early Stage Breast CancerView official trial listing → -
Completed NCT NCT00311636
Triptorelin in Preventing Early Menopause in Premenopausal Women Who Are Receiving Chemotherapy for Stage I, Stage II, or Stage III Breast Cancer That Has Been Removed By Surgery
Not yet reported Gruppo Italiano Mammella (GIM) 280 participants Est. completion 2008-04 18 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00313625
Melphalan and Busulfan Followed By Donor Peripheral Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Multiple Myeloma
Not yet reported Fred Hutchinson Cancer Center 20 participants 1 siteOther conditions: Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00316771
A Study of P38 Inhibitor (4) in Patients With Active Rheumatoid Arthritis (RA) on Stable Methotrexate Therapy
Not yet reported Hoffmann-La Roche 374 participants Est. completion 2008-03 114 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00317408
Combination Chemotherapy Followed By Stem Cell Transplant in Treating Young Patients With Progressive or Relapsed Anaplastic Large Cell Lymphoma
Not yet reported European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma 96 participants 98 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00317785
Total-Body Irradiation and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer and Other Diseases
Not yet reported Fred Hutchinson Cancer Center 50 participants 2 sitesOther conditions: Leukemia, Lymphoma, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00318110
Matched Unrelated Donor Transplant for Metastatic Renal Cell Carcinoma
Not yet reported Center for International Blood and Marrow Transplant Research 4 participants Est. completion 2009-03 5 sites Stand-aloneOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00322101
Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia
Not yet reported Fred Hutchinson Cancer Center 25 participants Est. completion 2014-10 8 sites Stand-aloneOther conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Childhood Acute Myeloid Leukemia in Remission, Childhood Myelodysplastic Syndromes, de Novo Myelodysplastic Syndromes, Myelodysplastic Syndrome With Isolated Del(5q), Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00323960
Five-year Actively Controlled Clinical Trial in New Onset Juvenile Dermatomyositis
Not yet reported Istituto Giannina Gaslini 139 participants Est. completion 2015-11-29 1 siteOther conditions: Juvenile DermatomyositisView official trial listing → -
Completed NCT NCT00326339
Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)
Not yet reported Rigel Pharmaceuticals 189 participants Est. completion 2007-12 38 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00331097
ELDA: Elderly Breast Cancer - Docetaxel in Adjuvant Treatment
Not yet reported National Cancer Institute, Naples 300 participants Est. completion 2014-11 8 sitesOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT00334672
Combination Chemotherapy Followed By Donor Stem Cell Transplant in Treating Patients With Hemophagocytic Lymphohistiocytosis
Not yet reported Children's Cancer and Leukaemia Group 288 participants 13 sitesOther conditions: Nonneoplastic ConditionView official trial listing → -
Terminated NCT NCT00335140
Rituximab and Combination Chemotherapy in Treating Patients With Primary Central Nervous System Lymphoma
Not yet reported Eastern Cooperative Oncology Group 26 participants Est. completion 2015-07 68 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00336024
Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma
Not yet reported Children's Oncology Group 91 participants Est. completion 2025-09-30 145 sites Stand-aloneOther conditions: Anaplastic Medulloblastoma, Medulloblastoma, Supratentorial Embryonal Tumor, Not Otherwise Specified, Untreated Childhood Supratentorial Primitive Neuroectodermal TumorView official trial listing → -
Status unknown NCT NCT00343369
Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia
Not yet reported Universitätsklinikum Hamburg-Eppendorf 550 participants 16 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00343785
Cyclophosphamide and Anti-thymocyte Globulin Followed By Methotrexate and Cyclosporine in Preventing Chronic Graft-Versus-Host Disease in Patients With Severe Aplastic Anemia Undergoing Donor Bone Marrow Transplant
Not yet reported Fred Hutchinson Cancer Center 21 participants Est. completion 2012-08 3 sites Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Completed NCT NCT00344253
Randomized, Controlled Trial to Test the Efficacy of Interferon Beta in the Treatment of Intermediate Uveitis
Not yet reported Heidelberg University 19 participants Est. completion 2012-01 1 siteOther conditions: Uveitis, Intermediate, Macular Edema, Multiple SclerosisView official trial listing → -
Completed NCT NCT00345748
A Study of Abatacept in Japanese Patients With Active Rheumatoid Arthritis While Receiving Methotrexate
Not yet reported Bristol-Myers Squibb 194 participants Est. completion 2007-11 38 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00346359
Fludarabine and Busulfan Followed by Donor Peripheral Stem Cell Transplant and Antithymocyte Globulin, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Cancer
Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2007-11 1 siteOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00348413
Thyroid Treatment Trial
Not yet reported Singapore National Eye Centre 80 participants Est. completion 2008-07 1 siteOther conditions: Graves OphthalmopathyView official trial listing → -
Status unknown NCT NCT00349674
WEGENT - Comparison of Methotrexate or Azathioprine as Maintenance Therapy for ANCA-Associated Vasculitides
Not yet reported Hospices Civils de Lyon 126 participants 1 siteOther conditions: Systemic Wegener's GranulomatosisView official trial listing → -
Terminated NCT NCT00354107
Ifosfamide, Carboplatin, Etoposide, and SGN-30 in Treating Young Patients With Recurrent Anaplastic Large Cell Lymphoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 5 participants Est. completion 2010-01 1 site Stand-aloneOther conditions: Anaplastic Large Cell Lymphoma, Recurrent Childhood Anaplastic Large Cell LymphomaView official trial listing → -
Completed NCT NCT00354393
Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma
Not yet reported The Cleveland Clinic 9 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Malignant MesotheliomaView official trial listing → -
Completed NCT NCT00355199
Comparison of HD Chemotherapy Followed by Auto-transplant and R-CHOP in High Risk Patients With DLBCL.
Not yet reported Gruppo Italiano Terapie Innovative nei Linfomi 246 participants Est. completion 2013-03 16 sites Stand-aloneOther conditions: Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT00357084
Methotrexate and Glucocorticoids in Treating Patients With Newly Diagnosed Acute Graft-Versus-Host Disease After Donor Stem Cell Transplant
Not yet reported Fred Hutchinson Cancer Center 53 participants 1 siteOther conditions: CancerView official trial listing → -
Completed NCT NCT00360685
Tacrolimus and Mycophenolate Mofetil (MMF) in GVHD Prophylactic Regimen Compared to Tacrolimus and Methotrexate (MTX
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 89 participants Est. completion 2011-01 1 siteOther conditions: Mucositis, Graft-versus-host DiseaseView official trial listing → -
Completed NCT NCT00361335
A Study of Safety and Effectiveness of Golimumab in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Centocor, Inc. 643 participants Est. completion 2009-09 72 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00365001
A Drug Interaction Study Between Tocilizumab, Methotrexate and Simvastatin on Patients With Rheumatoid Arthritis.
Not yet reported Hoffmann-La Roche 23 participants Est. completion 2008-04 11 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00368654
Evaluate Whether Combination Therapy With Methotrexate and Raptiva in Psoriasis Patients is Safe and Increases Efficacy
Not yet reported, Not yet reported University of California, Davis 12 participants Est. completion 2008-05 1 site Stand-aloneOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT00369226
Bortezomib Plus Tacrolimus and Methotrexate to Prevent Graft Versus Host Disease (GVHD) After Mismatched Allogeneic Non-Myeloablative Blood Stem Cell Transplantation
Not yet reported, Not yet reported Dana-Farber Cancer Institute 45 participants Est. completion 2011-09 2 sites Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT00369928
Evaluation of 2 Oral Doses of PG-760564 in Rheumatoid Arthritis (RA) Patients Receiving Methotrexate
Not yet reported Procter and Gamble 254 participants Est. completion 2008-01 53 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00372619
Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported Children's Oncology Group 74 participants Est. completion 2012-08 79 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00381680
Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 275 participants 173 sites Stand-aloneOther conditions: B-cell Childhood Acute Lymphoblastic Leukemia, L1 Childhood Acute Lymphoblastic Leukemia, L2 Childhood Acute Lymphoblastic Leukemia, Intermediate Risk Recurrent Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00382109
Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remission
Not yet reported Children's Oncology Group 146 participants Est. completion 2017-06-30 50 sites Stand-aloneOther conditions: B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Graft Versus Host Disease, L1 Childhood Acute Lymphoblastic Leukemia, L2 Childhood Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00385788
Allogeneic Blood Stem Cell Transplantation and Adoptive Immunotherapy for Hodgkin's Disease
Not yet reported M.D. Anderson Cancer Center 52 participants Est. completion 2016-08 1 site Stand-aloneOther conditions: Hodgkin's DiseaseView official trial listing → -
Completed NCT NCT00390793
Combination Chemotherapy and Dasatinib in Treating Participants With Philadelphia Positive or BCR-ABL Positive Acute Lymphoblastic Leukemia.
Not yet reported M.D. Anderson Cancer Center 107 participants Est. completion 2024-02-02 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, BCR-ABL1 Fusion Protein Expression, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Philadelphia Chromosome Positive, Recurrent Acute Lymphoblastic Leukemia, t(9;22)View official trial listing → -
Completed NCT NCT00392834
Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma
Not yet reported AIDS Malignancy Consortium 34 participants Est. completion 2013-07 13 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Status unknown NCT NCT00392886
Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating Young Patients With Previously Untreated Malignant Brain Tumors
Not yet reported Children's Hospital Los Angeles 120 participants 37 sites Stand-aloneOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00392990
Doxorubicin Hydrochloride Liposome and Rituximab With Combination Chemotherapy in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or Burkitt-Like Lymphoma
Not yet reported Northwestern University 25 participants Est. completion 2013-05-28 8 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00393471
Study Comparing Etanercept Plus Methotrexate to Either Etanercept or Methotrexate Alone in Rheumatoid Arthritis.
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 615 participants Est. completion 2001-10 88 sitesOther conditions: Active Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00395577
A Study in Rheumatoid Arthritis With an Investigational Oral p38 MAP Kinase Inhibitor VX-702
Not yet reported Vertex Pharmaceuticals Incorporated 120 participants Est. completion 2007-07 17 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00396747
A Comparison of Methotrexate Alone or Combined to Infliximab or to Pulse Methylprednisolone in Early Rheumatoid Arthritis: A Magnetic Resonance Imaging Study
Not yet reported Université Catholique de Louvain 45 participants Est. completion 2005-09 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00396812
Rituximab for the Treatment of Early Rheumatoid Arthritis (RA)
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 4 participants Est. completion 2009-07 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT00397501
BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer That Has Spread to the Brain
Not yet reported, Not yet reported OHSU Knight Cancer Institute Est. completion 2013-10Other conditions: Brain and Central Nervous System Tumors, Breast Cancer, Cognitive/Functional Effects, Drug/Agent Toxicity by Tissue/Organ, Psychosocial Effects of Cancer and Its TreatmentView official trial listing → -
Completed NCT NCT00400946
05-001: Treatment of Acute Lymphoblastic Leukemia in Children
Not yet reported Dana-Farber Cancer Institute 800 participants Est. completion 2019-06 8 sites Stand-aloneOther conditions: Drug/Agent Toxicity by Tissue/Organ, LeukemiaView official trial listing → -
Completed NCT NCT00402558
Alloreactive NK Cells for Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, LeukemiaView official trial listing → -
Completed NCT NCT00405275
Rheumatoid Arthritis: Comparison of Active Therapies in Patients With Active Disease Despite Methotrexate Therapy
Not yet reported US Department of Veterans Affairs 353 participants Est. completion 2012-05 37 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00406393
Sirolimus/Tacrolimus Versus Tacrolimus/Methotrexate for Preventing Graft-Versus-Host Disease (GVHD) (BMT CTN 0402)
Not yet reported Medical College of Wisconsin 304 participants Est. completion 2015-10 24 sitesOther conditions: Leukemia, Myelocytic, Acute, Leukemia, Lymphocytic, Acute, Leukemia, Myeloid, Chronic, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00406419
A Study of Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Continuing Methotrexate Treatment (STAGE)
Not yet reported Genentech, Inc. 1015 participants Est. completion 2015-04-22 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00408005
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
Not yet reported National Cancer Institute (NCI) 1895 participants Est. completion 2025-03-31 215 sites Stand-aloneOther conditions: T Acute Lymphoblastic Leukemia, T Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT00408278
Treatment of Newly Diagnosed Patients With Acute Promyelocytic Leukemia (PETHEMA LPA 2005)
Not yet reported PETHEMA Foundation 300 participants Est. completion 2013-12 42 sitesOther conditions: Acute Promyelocytic LeukemiaView official trial listing → -
Completed NCT NCT00409838
A Phase III Study of Abatacept in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Not yet reported Bristol-Myers Squibb 113 participants Est. completion 2011-12 7 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00413660
Comparison Of 6 CP-690,550 Doses Vs.Placebo, Each Combined With Methotrexate, For The Treatment Of Rheumatoid Arthritis
Not yet reported Pfizer 509 participants Est. completion 2008-08 82 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT00415935
PRINTO (the Paediatric Rheumatology International Trials Organisation)
Institute of Child Health Est. completion 2006-12 1 siteOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT00416819
Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Primary CNS Lymphoma
Not yet reported University of California, San Francisco 10 participants Est. completion 2012-02 Stand-aloneOther conditions: Brain and Central Nervous System Tumors, LymphomaView official trial listing → -
Completed NCT NCT00419809
SB-681323-Methotrexate Interaction Study
Not yet reported GlaxoSmithKline 18 participants Est. completion 2005-12 2 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00420199
A Phase IIIb Study of BMS-188667 in Subjects With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate
Not yet reported Bristol-Myers Squibb 50 participants Est. completion 2010-05 10 sitesOther conditions: Active Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00420927
Study of the Optimal Protocol for Methotrexate and Adalimumab Combination Therapy in Early Rheumatoid Arthritis
Not yet reported Abbott 1032 participants Est. completion 2010-07 170 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00422227
Study Comparing Etanercept With Usual DMARD Therapy in Subjects With Rheumatoid Arthritis in the Asia Pacific Region
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 300 participants Est. completion 2009-03 27 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00422383
A Study of Retreatment With MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (RA)
Not yet reported Hoffmann-La Roche 378 participants Est. completion 2013-03 91 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00422942
A Pharmacokinetic and Pharmacodynamic Study of MabThera (Rituximab) Plus Methotrexate in Patients With Rheumatoid Arthritis (RA)
Not yet reported Hoffmann-La Roche 3 participants Est. completion 2010-06 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00424294
A Study Of CP-195543 And Celecoxib Dual Therapy In Subjects With Rheumatoid Arthritis
Not yet reported Pfizer 70 participants Est. completion 2008-02 39 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00424346
Efficacy, Safety and Tolerability of ACZ885 in Patients With Active Rheumatoid Arthritis
Not yet reported Novartis 274 participants Est. completion 2009-10 17 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00424502
A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a TNF-Blocker.
Not yet reported Hoffmann-La Roche 20 participants Est. completion 2009-10 3 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00424645
Voraxaze for Delayed Methotrexate Clearance
Not yet reported, Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2008-01 1 siteOther conditions: Hematologic Malignancy, Solid TumorView official trial listing → -
Completed NCT NCT00425321
Safety and Effectiveness Study of RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 259 participants Est. completion 2008-01 42 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00426101
Treatment Protocol for Hemophagocytic Lymphohistiocytosis 2004
Not yet reported Karolinska University Hospital 368 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: Hemophagocytic LymphohistiocytosisView official trial listing → -
Terminated NCT NCT00427934
Maraviroc in Rheumatoid Arthritis
Not yet reported Pfizer 128 participants Est. completion 2008-10 44 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00430118
Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia
Not yet reported University Hospital Schleswig-Holstein 4559 participants Est. completion 2012-01 76 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00432432
Combination Methotrexate and Infliximab
Not yet reported Chinese University of Hong Kong 38 participants Est. completion 2006-10Other conditions: Ankylosing SpondylitisView official trial listing → -
Completed NCT NCT00437060
Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia
Children's Oncology Group 233 participants 112 sitesOther conditions: Childhood B Acute Lymphoblastic Leukemia, Childhood T Acute Lymphoblastic Leukemia, Cognitive Side Effects of Cancer Therapy, Long-Term Effects Secondary to Cancer Therapy in Children, Neurotoxicity Syndrome, Psychological Impact of Cancer, Untreated Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00439283
Study of Two Schedules of Infliximab Maintenance Therapy in Ankylosing Spondylitis
Not yet reported Association de Recherche Clinique en Rhumatologie 240 participants Est. completion 2004-12 31 sitesOther conditions: Ankylosing SpondylitisView official trial listing → -
Terminated NCT NCT00439296
ABT-751 With Chemotherapy for Relapsed Pediatric ALL
Not yet reported, Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 9 participants Est. completion 2009-09-23 5 sites Stand-aloneOther conditions: Recurrent Pediatric ALL, Relapsed Pediatric ALL, Acute Lymphoblastic Leukemia, Refractory Pediatric ALLView official trial listing → -
Completed NCT NCT00439556
Bortezomib and Chemotherapy in Treating Participants With Lymphoid Malignancies Undergoing Stem Cell Transplant
Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2018-06-07 1 site Stand-aloneOther conditions: CD20 Positive, Hematopoietic and Lymphoid Cell Neoplasm, Lymphocytic Neoplasm, LymphomaView official trial listing → -
Completed NCT NCT00440492
Study To Evaluate The Pharmacokinetic Interaction Between PLA-695 And Methotrexate In Adults With Rheumatoid Arthritis
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer Est. completion 2007-11 9 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00440726
Bortezomib With Chemotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia (ALL)
Not yet reported, Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 31 participants Est. completion 2011-02-26 24 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00441961
Treatment With High Dose Methotrexate in Patients With Eosinophilic Fasciitis
Not yet reported Radboud University Medical Center 6 participants Est. completion 2011-06 1 siteOther conditions: FasciitisView official trial listing → -
Completed NCT NCT00443430
Trial of Early Aggressive Drug Therapy in Juvenile Idiopathic Arthritis
Not yet reported Seattle Children's Hospital 85 participants Est. completion 2010-10 15 sitesOther conditions: Juvenile Chronic Polyarthritis, Juvenile Idiopathic Arthritis, Juvenile Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00443950
Study Evaluating the Efficacy and Safety of Etanercept in Chinese Subjects With Rheumatoid Arthritis
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 150 participants Est. completion 2007-07 6 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00445744
Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome
Not yet reported Fred Hutchinson Cancer Center 52 participants Est. completion 2013-06 1 site Stand-aloneOther conditions: Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Childhood Acute Myeloid Leukemia in Remission, Childhood Myelodysplastic Syndromes, de Novo Myelodysplastic Syndromes, Essential Thrombocythemia, Myelodysplastic Syndrome With Isolated Del(5q), Polycythemia Vera, Previously Treated Myelodysplastic Syndromes, Primary Myelofibrosis, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Secondary Myelofibrosis, Untreated Adult Acute Myeloid Leukemia, Untreated Childhood Acute Myeloid Leukemia and Other Myeloid MalignanciesView official trial listing → -
Completed NCT NCT00445770
Study Evaluating the Efficacy and Safety of Etanercept and Methotrexate in Japanese Subjects With Rheumatoid Arthritis
Not yet reported Pfizer 550 participants Est. completion 2010-07 41 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00446784
Study Of The Safety Of CE 224,545 And Methotrexate In Patients With Rheumatoid Arthritis
Not yet reported Pfizer 20 participants Est. completion 2007-08 5 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00448201
Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease
Not yet reported UNC Lineberger Comprehensive Cancer Center 71 participants Est. completion 2012-05-23 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00448357
Allogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen
Not yet reported, Not yet reported UNC Lineberger Comprehensive Cancer Center 54 participants Est. completion 2015-11 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00450801
R-MACLO-IVAM and Thalidomide in Untreated Mantle Cell Lymphoma
Not yet reported University of Miami 22 participants Est. completion 2015-07 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT00450983
Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseases
Not yet reported Fred Hutchinson Cancer Center 1 participants Est. completion 2010-07 2 sitesOther conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT00455286
a Phase II Study in Primary Central Nervous System Lymphoma
Not yet reported National Health Research Institutes, Taiwan 25 participants Est. completion 2011-11 4 sitesOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT00458146
A Phase 2 Study to Evaluate the Efficacy and Safety of 60mg of MM-093 in Patients With Active Rheumatoid Arthritis
Not yet reported Merrimack Pharmaceuticals 100 participants 20 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00458250
Feasibility of Haploidentical Hematopoietic Stem Cell Transplantation Using CAMPATH-1H
Not yet reported Tehran University of Medical Sciences 10 participants Est. completion 2008-02 1 siteOther conditions: Leukemia, Myeloid, Acute, Leukemia, Lymphoblastic, AcuteView official trial listing → -
Completed NCT NCT00458848
Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 470 participants Est. completion 2014-03 66 sitesOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00458861
BG9924 in Combination With Methotrexate for Participants With Active Rheumatoid Arthritis
Not yet reported Biogen 115 participants Est. completion 2008-10 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00462072
Centocor Microarray Study of Patients
Not yet reported University of Rochester 31 participants Est. completion 2010-08 1 siteOther conditions: Rheumatoid Arthritis, Psoriatic Arthritis, Psoriasis, Crohn's DiseaseView official trial listing → -
Completed NCT NCT00462345
A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Therapies.
Not yet reported Hoffmann-La Roche 40 participants Est. completion 2009-07 4 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00463008
Pharmacologic Study of Methotrexate in Patients Undergoing Stereotactic Biopsy for Recurrent High-Grade Glioma
Not yet reported New Approaches to Brain Tumor Therapy Consortium 12 participants Est. completion 2007-04Other conditions: Brain and Central Nervous System TumorsView official trial listing → -
Status unknown NCT NCT00464997
The Effect of Low Dose Aspirin on the Pharmacokinetics of Methotrexate
Tel-Aviv Sourasky Medical Center 30 participantsOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00465933
Treatment of Acute Promyelocytic Leukemia With All-Trans Retinoic Acid (ATRA) and Idarubicin (AIDA)
Not yet reported PETHEMA Foundation Est. completion 2007-11 2 sitesOther conditions: Acute Promyelocytic LeukemiaView official trial listing → -
Completed NCT NCT00466258
LINFOTARGAM: Treatment With Chemotherapy Plus Rituximab and Highly Active Antiretroviral Therapy in Patients With Diffuse Large B Cell Lymphoma and Infection With the Human Immunodeficiency Virus (HIV)
Not yet reported PETHEMA Foundation 50 participants Est. completion 2009-11 15 sitesOther conditions: HIV Infections, Diffuse Large B Cell LymphomaView official trial listing → -
Completed NCT NCT00468546
A Study to Evaluate the Safety and Efficacy of MabThera (Rituximab) in Combination With Methotrexate (MTX) in Participants With Active Rheumatoid Arthritis Who Failed on Anti-Tumor Necrosis Factor Alpha Therapy
Not yet reported Hoffmann-La Roche 520 participants Est. completion 2012-07 115 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT00470223
Combined Chemotherapy With or Without Zoledronic Acid for Patients With Osteosarcoma
Not yet reported UNICANCER 318 participants Est. completion 2026-12 37 sites Stand-aloneOther conditions: SarcomaView official trial listing → -
Completed NCT NCT00470522
Study of Methotrexate in Lupus Erythematosus
Not yet reported University Health Network, Toronto 86 participants Est. completion 2001-12 1 siteOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Completed NCT NCT00476190
ALL Adult Consortium Trial: Adult ALL Trial
Not yet reported Dana-Farber Cancer Institute 112 participants Est. completion 2020-03 15 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT00476996
A Study of Ocrelizumab Compared to Placebo in Patients With Active Rheumatoid Arthritis Who Don't Have a Response to Anti-TNF-α Therapy (SCRIPT)
Not yet reported Genentech, Inc. 836 participants Est. completion 2018-05-14 266 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00477412
Bortezomib, Rituximab and Combination Chemotherapy in Treating Participants With Mantle Cell Lymphoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 107 participants Est. completion 2020-10-28 1 site Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT00480272
Prospective Study on Intensive Early Rheumatoid Arthritis Treatment
Not yet reported Fondazione IRCCS Policlinico San Matteo di Pavia 251 participants Est. completion 2017-03-01 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Approved For Marketing NCT NCT00481559
Treatment Protocol of Voraxaze for Patients Experiencing or at Risk of Methotrexate Toxicity
BTG International Inc.Other conditions: NeoplasmsView official trial listing → -
Completed NCT NCT00482833
Phase III Trial in Acute Promyelocytic Leukemia Patients
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 276 participants Est. completion 2019-10-17 110 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00484289
A Phase III Study of Abatacept in Japanese Subjects With Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 217 participants Est. completion 2010-12 39 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00485589
A Study of Ocrelizumab in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Are Naive to Methotrexate (FILM)
Not yet reported Genentech, Inc. 613 participants Est. completion 2013-08-29 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00487825
Safety and Efficacy of Intravenous ACZ885 and Oral Methotrexate Therapy in Patients With Early Rheumatoid Arthritis
Not yet reported Novartis 78 participants Est. completion 2008-12 22 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT00488605
H-9926-LCH III: Treatment Protocol of the Third International Study for Langerhans Cell Histiocytosis
Not yet reported University of New Mexico Est. completion 2023-08-01 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00489203
Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer
Not yet reported Fred Hutchinson Cancer Center 140 participants 2 sites Stand-aloneObstructive sleep apnea Other conditions: Hematopoietic/Lymphoid Cancer, Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Atypical Chronic Myeloid Leukemia, Blastic Phase Chronic Myelogenous Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Chronic Eosinophilic Leukemia, Chronic Myelomonocytic Leukemia, Chronic Neutrophilic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Contiguous Stage II Adult Burkitt Lymphoma, Contiguous Stage II Adult Diffuse Large Cell Lymphoma, Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Contiguous Stage II Adult Lymphoblastic Lymphoma, Contiguous Stage II Grade 1 Follicular Lymphoma, Contiguous Stage II Grade 2 Follicular Lymphoma, Contiguous Stage II Grade 3 Follicular Lymphoma, Contiguous Stage II Mantle Cell Lymphoma, Contiguous Stage II Marginal Zone Lymphoma, Contiguous Stage II Small Lymphocytic Lymphoma, de Novo Myelodysplastic Syndromes, Essential Thrombocythemia, Extramedullary Plasmacytoma, Graft Versus Host Disease, Isolated Plasmacytoma of Bone, Juvenile Myelomonocytic Leukemia, Meningeal Chronic Myelogenous Leukemia, Myelodysplastic/Myeloproliferative Disease, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Burkitt Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Grade 1 Follicular Lymphoma, Noncontiguous Stage II Grade 2 Follicular Lymphoma, Noncontiguous Stage II Grade 3 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Noncontiguous Stage II Marginal Zone Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Previously Treated Myelodysplastic Syndromes, Primary Myelofibrosis, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic Syndromes, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Diffuse Small Cleaved Cell Lymphoma, Stage I Adult Hodgkin Lymphoma, Stage I Adult Immunoblastic Large Cell Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Adult T-cell Leukemia/Lymphoma, Stage I Childhood Hodgkin Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage I Cutaneous T-cell Non-Hodgkin Lymphoma, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Multiple Myeloma, Stage I Mycosis Fungoides/Sezary Syndrome, Stage I Small Lymphocytic Lymphoma, Stage II Adult Hodgkin Lymphoma, Stage II Adult T-cell Leukemia/Lymphoma, Stage II Chronic Lymphocytic Leukemia, Stage II Cutaneous T-cell Non-Hodgkin Lymphoma, Stage II Multiple Myeloma, Stage II Mycosis Fungoides/Sezary Syndrome, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Hodgkin Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Adult T-cell Leukemia/Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage III Cutaneous T-cell Non-Hodgkin Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Multiple Myeloma, Stage III Mycosis Fungoides/Sezary Syndrome, Stage III Small Lymphocytic Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Hodgkin Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Adult T-cell Leukemia/Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Mycosis Fungoides/Sezary Syndrome, Stage IV Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT00492856
S0521, Combination Chemotherapy With or Without Gemtuzumab Followed By Tretinoin, Mercaptopurine, and Methotrexate or Observation in Treating Patients With Acute Promyelocytic Leukemia
Not yet reported SWOG Cancer Research Network 105 participants Est. completion 2016-05-04 210 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00494897
PETHEMA LAL-RI/96: Treatment for Patients With Standard Risk Acute Lymphoblastic Leukemia
Not yet reported PETHEMA Foundation 374 participants Est. completion 2007-12 87 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00496665
ZD6474 (Zactima) and Metronomic Chemotherapy in Advanced Breast Cancer
Not yet reported Dana-Farber Cancer Institute 25 participants Est. completion 2009-03 2 sites Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT00498589
Comparison of Methotrexate vs Placebo in Corticosteroid-dependent Ulcerative Colitis
Not yet reported Centre Hospitalier Universitaire de Besancon 110 participants Est. completion 2014-06 22 sitesOther conditions: Ulcerative ColitisView official trial listing → -
Terminated NCT NCT00499889
Imatinib Mesylate, Busulfan, Fludarabine, and Antithymocyte Globulin for CML Patients
Not yet reported M.D. Anderson Cancer Center 42 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00502853
A Pilot Study of MabThera (Rituximab) Evaluated by MRI in Patients With Rheumatoid Arthritis.
Not yet reported Hoffmann-La Roche 10 participants Est. completion 2010-07-23 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00502996
A Non-Comparative Study to Assess the Safety of MabThera (Rituximab) in Patients With Rheumatoid Arthritis.
Not yet reported Hoffmann-La Roche 246 participants Est. completion 2008-12 49 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00503594
Methotrexate and Temozolomide Versus Methotrexate, Procarbazine, Vincristine and Cytarabine
Not yet reported Assistance Publique - Hôpitaux de Paris 92 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00504777
A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Agents.
Not yet reported Hoffmann-La Roche 36 participants Est. completion 2010-03 10 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00505232
Safety Study to Evaluate Induction and Consolidation Treatment in Patients With Mantle Cell Lymphoma (LCM-04-02)
Not yet reported CABYC 30 participants Est. completion 2011-05 16 sites Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT00506155
Neoadjuvant Chemotherapy With Methotrexate, Vinblastine, Adriamycin and Cisplatin (M-VAC) Plus Avastin in Patients With Urothelial Cancer
Not yet reported M.D. Anderson Cancer Center 60 participants Est. completion 2014-08 1 site Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT00506922
Phase I/II Study of Pentostatin Combined With Tacrolimus and Mini-Methotrexate for GVHD Prevention After MUD BMT
Not yet reported, Not yet reported M.D. Anderson Cancer Center 150 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00507403
Infliximab and Methotrexate in Ankylosing Spondylitis
Not yet reported University Hospital, Tours 30 participants Est. completion 2009-12 2 sites Stand-aloneOther conditions: Ankylosing SpondylitisView official trial listing → -
Completed NCT NCT00508768
A Study of Oral SCIO-469 Pharmacokinetics (Study of a Drug in the Body to Watch How the Drug is Absorbed, Distributed, Metabolized and Eliminated Over a Period of Time) in the Body of Female Patients With Active Rheumatoid Arthritis
Not yet reported Scios, Inc. 16 participants Est. completion 2002-12Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00509678
Rituxan With or Without Methotrexate in Psoriatic Arthritis
Not yet reported Swedish Medical Center 6 participants Est. completion 2010-03 4 sitesOther conditions: Psoriatic ArthritisView official trial listing → -
Withdrawn NCT NCT00513188
Combination Chemotherapy and Denileukin Diftitox in Treating Patients With Newly Diagnosed T-Cell Non-Hodgkin Lymphoma
Not yet reported University of Miami 1 siteOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00513474
Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant
Not yet reported Massachusetts General Hospital 46 participants Est. completion 2013-02-12 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00513981
High-Dose Methotrexate in Treating Young Patients With Solid Tumors
Not yet reported Children's Cancer and Leukaemia Group 36 participants Est. completion 2009-08 21 sitesOther conditions: Brain and Central Nervous System Tumors, Sarcoma, Unspecified Childhood Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00516152
Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT
Not yet reported University of California, San Francisco 36 participants Est. completion 2007-11 1 siteOther conditions: Chronic Myeloid Leukemia, Acute Myelogenous Leukemia, Myelodysplasia, Acute Lymphocytic Leukemia, Severe Aplastic Anemia, Non-Hodgkin's Lymphoma, Lymphoproliferative Disease, Multiple Myeloma, Advanced Myeloproliferative DiseaseView official trial listing → -
Terminated NCT NCT00516750
Gene Expression Profiling in Patients With Invasive Bladder Cancer Receiving Methotrexate, Vinblastine, Doxorubicin, and Cisplatin
Not yet reported Kyoto University 100 participants Est. completion 2009-02 5 sitesOther conditions: Bladder CancerView official trial listing → -
Terminated NCT NCT00517699
A Study of MabThera (Rituximab) in Primary Central Nervous System Lymphoma.
Not yet reported Hoffmann-La Roche 5 participants Est. completion 2009-03 2 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
No Longer Available NCT NCT00517894
Dose-Dense Therapy in Aggressive Lymphoma
Arbeitsgemeinschaft medikamentoese TumortherapieOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00520130
Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune System
Not yet reported, Not yet reported National Cancer Institute (NCI) 92 participants Est. completion 2018-12-31 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, Hodgkin's Lymphoma, Non-Hodgkin's Disease, Acute Leukemia, Multiple MyelomaView official trial listing → -
Completed NCT NCT00520572
A 6-month Randomised, Double-blind, Open Arm Comparator, Phase IIb, With AZD9056, in Patients With Rheumatoid Arthritis (RA)
Not yet reported AstraZeneca 385 participants Est. completion 2009-03 51 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00521924
Induction of Remission in RA Patients at Low Disease Activity by Additional Infliximab Therapy (Study P04644AM1) (TERMINATED)
Not yet reported Merck Sharp & Dohme LLC 8 participants Est. completion 2008-04Other conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00523328
BG9924 in Combination With Methotrexate Extension of Study 104RA203 (NCT 00458861)
Not yet reported Biogen 72 participants Est. completion 2008-10 4 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00523692
Remission Induction in Very Early Rheumatoid Arthritis
Not yet reported University Hospital Birmingham 20 participants 2 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00525213
Study to Evaluate the Efficacy and Safety of Orally Administered Rob 803 When Added to Methotrexate
Not yet reported OxyPharma 224 participants Est. completion 2009-08 34 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00526175
LAL-BR/2001: Study Treatment to Low Risk ALL
Not yet reported PETHEMA Foundation 150 participants Est. completion 2015-12 25 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00526409
LAL-AR-N-2005:Study Treatment for Children High Risk Acute Lymphoblastic Leukemia
Not yet reported PETHEMA Foundation 40 participants Est. completion 2014-10 4 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00531817
A Study of Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 619 participants Est. completion 2011-03 157 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00535782
A Study of the Effect of Tocilizumab on Markers of Atherogenic Risk in Patients With Moderate to Severe Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 132 participants Est. completion 2011-01-31 40 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00536978
Natural Killer (NK) Cell Adback After Allogeneic Stem Cell Transplant With Campath-IH Plus Chemorx for Patients With Lymphoid Malignancies
Not yet reported M.D. Anderson Cancer Center 22 participants Est. completion 2010-11 1 site Stand-aloneOther conditions: Lymphoma, LeukemiaView official trial listing → -
Completed NCT NCT00537550
Adult ALL Treatment at Diagnosis
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto Est. completion 2006-06 5 sitesOther conditions: Leukemia, Lymphocytic, AcuteView official trial listing → -
Completed NCT NCT00538902
Safety and Efficacy Study of Adalimumab in Adult Chinese Rheumatoid Arthritis Subjects Treated With Methotrexate
Not yet reported, Not yet reported Abbott 302 participants Est. completion 2009-12 11 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00539838
A Study to Evaluate Two Doses of Ocrelizumab in Patients With Active Systemic Lupus Erythematosus (BEGIN)
Not yet reported Genentech, Inc. 33 participants Est. completion 2011-07-12 Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Terminated NCT NCT00540995
Busulfan, Etoposide, and Intensity-Modulated Radiation Therapy Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Myeloid Cancer
Not yet reported, Not yet reported City of Hope Medical Center 25 participants Est. completion 2011-08-09 1 site Stand-aloneOther conditions: Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Blastic Phase Chronic Myelogenous Leukemia, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Refractory Anemia With Excess BlastsView official trial listing → -
Completed NCT NCT00544154
Efficacy and Safety of CDP870 and Methotrexate Compared to Methotrexate Alone in Subjects With Rheumatoid Arthritis
Not yet reported UCB Pharma 247 participants Est. completion 2004-01Other conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00544232
Preoperative Epirubicin Paclitaxel Aranesp Study (PREPARE)
Not yet reported GBG Forschungs GmbH 720 participants Est. completion 2006-09 Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00548431
NOPHO ALL-2008 Pilot Study on Consolidation Therapy for Children and Adolescents With Acute Lymphoblastic Leukemia
Not yet reported Copenhagen University Hospital, Rigshospitalet 38 participants Est. completion 2009-05 3 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, AcuteView official trial listing → -
Completed NCT NCT00549848
Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
Not yet reported St. Jude Children's Research Hospital 600 participants Est. completion 2022-03-26 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00550355
Dose-Escalating Multiple Dose Study of PD-0360324 in Combination With Methotrexate in Patients With Rheumatoid Arthritis
Not yet reported Pfizer 78 participants Est. completion 2009-06 25 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT00550992
Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia
Not yet reported Dutch Childhood Oncology Group 445 participants 13 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00551460
S0535, Gemtuzumab and Combination Chemotherapy in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia
Not yet reported SWOG Cancer Research Network 78 participants Est. completion 2018-02-05 192 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00553202
Donor Stem Cell Transplant in Treating Young Patients With Acute Myeloid Leukemia With Monosomy 7, -5/5q-, High FLT3-ITD AR, or Refractory or Relapsed Acute Myelogenous Leukemia
Not yet reported Children's Oncology Group 158 participants Est. completion 2020-03-31 52 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00554164
Positron Emission Tomography Guided Therapy of Aggressive Non-Hodgkin's Lymphomas
Not yet reported University Hospital, Essen 1073 participants Est. completion 2017-03 1 site Stand-aloneOther conditions: Lymphoma, High-gradeView official trial listing → -
Completed NCT NCT00554710
Top Down Versus Step Up Strategies in Crohn's Disease
Not yet reported Belgian Inflammatory Bowel Disease Research and Development (BIRD) VZW 129 participants Est. completion 2004-01 1 site Stand-aloneOther conditions: Crohn's DiseaseView official trial listing → -
Terminated NCT NCT00555048
Alemtuzumab, Busulfan, and Cyclophosphamide Followed By a Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 1 participants 2 sites Stand-aloneOther conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00555542
An Analysis of Peripheral Blood T Cell Subsets on Rheumatoid Arthritis
Not yet reported Chinese University of Hong Kong 10 participants Est. completion 2008-05 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00556894
Oral CF101 Tablets and Methotrexate Treatment in Rheumatoid Arthritis Patients
Not yet reported Can-Fite BioPharma 253 participants Est. completion 2009-04 26 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00557193
Combination Chemotherapy With or Without Lestaurtinib in Treating Younger Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 218 participants Est. completion 2024-06-30 170 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Undifferentiated Leukemia, Childhood T Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00558519
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Alliance for Clinical Trials in Oncology 318 participants Est. completion 2024-06-24 Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00559585
Methotrexate-Inadequate Response Study
Not yet reported Bristol-Myers Squibb 2492 participants Est. completion 2014-09 203 sitesOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Status unknown NCT NCT00563589
Mycophenolate Mofetil for the Prophylaxis of Graft-versus-host Disease in High Risk Allogeneic Stem Cell Transplantation
Not yet reported Hospital Authority, Hong Kong 30 participants Est. completion 2008-12 1 siteOther conditions: Graft vs Host Disease, Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT00563849
Leflunomide + Methotrexate in Rheumatoid Arthritis
Not yet reported Sanofi 74 participants Est. completion 2004-08 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00565409
Study Comparing Etanercept in Combination With Methotrexate in Subjects With Rheumatoid Arthritis
Not yet reported Pfizer 834 participants Est. completion 2011-05 81 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00570817
Prevention of Methotrexate Induced Nephrotoxicity and Prolonged Drug Elimination Time With 12 Hours Prehydration
Not yet reported University of Aarhus 47 participants Est. completion 2010-10 1 siteOther conditions: Methotrexate Induced NephrotoxicityView official trial listing → -
Completed NCT NCT00574496
Combination Chemotherapy Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or High-Risk Primary Refractory Hodgkin Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 25 participants Est. completion 2022-08-02 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00576433
A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor.
Not yet reported Hoffmann-La Roche 60 participants Est. completion 2010-11 18 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00577122
Medroxyprogesterone +/- Cyclophosphamide & Methotrexate in Hormone Receptor-Negative Recurrent/Metastatic Breast Cancer
Not yet reported Indiana University 30 participants Est. completion 2011-12 7 sites Stand-aloneOther conditions: Estrogen Receptor-negative Breast Cancer, Progesterone Receptor-negative Breast Cancer, Recurrent Breast Cancer, Stage IV Breast CancerView official trial listing → -
Completed NCT NCT00578305
A Study of Rituximab (MabThera®/Rituxan®) in Patients With Rheumatoid Arthritis and Inadequate Response to Methotrexate
Not yet reported Hoffmann-La Roche 185 participants Est. completion 2013-05 60 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00578903
Allogeneic Stem Cell Transplant for Patients With Severe Aplastic Anemia
Not yet reported Baylor College of Medicine 22 participants Est. completion 2012-07 2 sites Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Completed NCT NCT00579644
Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone
Not yet reported University of Nebraska 91 participants Est. completion 2006-05-31 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00579878
Triple III Comparison of Leflunomide Alone Versus Two DMARD Combinations in the Treatment of Rheumatoid Arthritis
Not yet reported University of Nebraska 69 participants Est. completion 2010-03-11 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00580840
Dosing Flexibility Study in Patients With Rheumatoid Arthritis
Not yet reported UCB Pharma 333 participants Est. completion 2011-03 66 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00584766
Intensive Combo Chemo With Autologous BM Rescue for Metastatic Breast Cancer
Not yet reported University of Oklahoma 21 participants Est. completion 2002-05 1 site Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT00586846
Phase II Study of Chemotherapy and Pamidronate for the Treatment of Newly Diagnosed Osteosarcoma
Not yet reported Memorial Sloan Kettering Cancer Center 40 participants Est. completion 2009-02 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT00587873
Sequential Administration of Oral 6-Thioguanine (6-TG) After Methotrexate (MTX) in Patients With Relapsed Hodgkin's Disease (Phase II)
Not yet reported Memorial Sloan Kettering Cancer Center 18 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Hodgkin's DiseaseView official trial listing → -
Completed NCT NCT00588536
Study of Sequential Administration of Oral 6-Thioguanine After Methotrexate in Patients With LCH
Not yet reported Memorial Sloan Kettering Cancer Center 5 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Langerhans Cell HistiocytosisView official trial listing → -
Completed NCT NCT00589563
Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer
Not yet reported City of Hope Medical Center 32 participants Est. completion 2012-02 2 sites Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Infection, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous Condition, Secondary Myelofibrosis, Small Intestine CancerView official trial listing → -
Completed NCT NCT00594815
Combined Immunochemotherapy Followed By Reduced Dose Radiation Therapy (RT) for Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 52 participants Est. completion 2016-02-23 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00595413
Atacicept in Anti-Tumor Necrosis Factor Alpha-naïve Subjects With Rheumatoid Arthritis (AUGUST II)
Not yet reported EMD Serono 311 participants Est. completion 2009-10 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00596154
Rituximab, Methotrexate, Procarbazine and Vincristine Followed by High-dose Chemotherapy With Autologous Stem-cell Rescue in Newly-diagnosed Primary CNS Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 33 participants Est. completion 2023-02-02 3 sites Stand-aloneOther conditions: CNS Lymphoma, CNS Brain Cancer, Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT00599937
APL93: Timing of CxT and Role of Maintenance
Not yet reported Groupe d'etude et de travail sur les leucemies aigues promyelocytaires 576 participants Est. completion 1998-12 Stand-aloneOther conditions: Leukemia, Promyelocytic, AcuteView official trial listing → -
Active, not recruiting NCT NCT00602667
Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glioma or Ependymoma
Not yet reported St. Jude Children's Research Hospital 293 participants Est. completion 2029-04 6 sites Stand-aloneOther conditions: Brain and Central Nervous System TumorsView official trial listing → -
Completed NCT NCT00603512
Comparison Of 4 CP-690,550 Doses Vs. Placebo, Each Combined With Methotrexate, For The Treatment Of Rheumatoid Arthritis in Japan
Not yet reported Pfizer 140 participants Est. completion 2008-09 18 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00605735
PoC in Rheumatoid Arthritis With Methotrexate
Not yet reported Bristol-Myers Squibb 121 participants Est. completion 2009-09 28 sitesOther conditions: Rheumatoid Arthritis, NOSView official trial listing → -
Terminated NCT NCT00609739
Cytosine Arabinoside and Mitoxantrone for Patients With Juvenile Myelomonocytic Leukemia Receiving Repeat Stem Cell Transplantation
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 1 participants Est. completion 2010-06 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00610883
LSA4 Protocol for the Treatment of Advanced Pediatric and Adolescent Non-Hodgkins Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 17 participants Est. completion 2008-12 1 site Stand-aloneOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Terminated NCT NCT00611455
Investigating Clinical Efficacy of Ofatumumab in Adult Rheumatoid Arthritis (RA) Patients Who Had an Inadequate Response to MTX Therapy
Not yet reported GlaxoSmithKline 265 participants Est. completion 2013-07-15 45 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00612274
Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell Transplantation
Not yet reported Yale University 26 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: Stem Cell TransplantationView official trial listing → -
Completed NCT NCT00613457
Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia
Not yet reported Associazione Italiana Ematologia Oncologia Pediatrica 2039 participants Est. completion 2006-07 Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00615901
Dose Dense Adjuvant CMF (Cyclophosphamide, Methotrexate, Fluorouracil) at 14 and 10-11 Day Intervals for Women With Early Stage Breast Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 38 participants Est. completion 2010-06 5 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT00616122
Sunitinib, Cyclophosphamide, and Methotrexate in Treating Patients With Metastatic Breast Cancer
Not yet reported, Not yet reported University of California, San Francisco 32 participants Est. completion 2012-12-01 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00618501
Imatinib Mesylate and Combination Chemotherapy With or Without a Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Asan Medical Center 50 participants Est. completion 2009-01 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00619879
Myeloablative Hematopoietic Progenitor Cell Transplantation (HPCT) for Pediatric Malignancies
Ann & Robert H Lurie Children's Hospital of Chicago 81 participants Est. completion 2019-02-07 1 siteOther conditions: Leukemia, Myelogenous, Chronic, Leukemia, Lymphoblastic, Acute, Leukemia, Myelogenous, Acute, Myeloproliferative-Myelodysplastic Diseases, Lymphoma, MalignantView official trial listing → -
Completed NCT NCT00619905
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACZ885 in Patients With Rheumatoid Arthritis With Ongoing Treatment With Methotrexate
Not yet reported, Not yet reported Novartis 53 participants Est. completion 2005-08 10 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00620685
A Study To Evaluate The Safety And Pharmacokinetic Profile Of A P38 Inhibitor (PH-797804) In Subjects With Rheumatoid Arthritis Who Are Also Taking Methotrexate
Not yet reported Pfizer 27 participants Est. completion 2008-10 7 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Withdrawn NCT NCT00621036
Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma
Not yet reported University of Texas Southwestern Medical Center Est. completion 2008-12-08 1 site Stand-aloneOther conditions: Brain and Central Nervous System Tumors, Lymphoma, Lymphoproliferative Disorder, Small Intestine CancerView official trial listing → -
Completed NCT NCT00627666
Donor Stem Cell Transplant After Busulfan, Fludarabine, and Antithymocyte Globulin in Treating Patients With Hematological Cancer
Not yet reported Asan Medical Center 52 participants Est. completion 2010-06 1 siteOther conditions: Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00628095
Study of CE-224,535 A Twice Daily Pill To Control Rheumatoid Arthritis In Patients Who Have Not Totally Improved With Methotrexate
Not yet reported Pfizer 100 participants Est. completion 2009-02-04 27 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Terminated NCT NCT00632827
Treatment of PTCL With Aggressive Induction Therapy Followed by Autologous SCT Using Denileukin Diftitox (Ontak)
Not yet reported University of California, San Francisco 21 participants Est. completion 2016-06-23 1 site Stand-aloneOther conditions: Peripheral T-Cell LymphomaView official trial listing → -
Terminated NCT NCT00634322
High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma
Not yet reported BTG International Inc. 7 participants Est. completion 2009-04Obstructive sleep apneaView official trial listing → -
Completed NCT NCT00634504
Open-label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze
Not yet reported BTG International Inc. 20 participants Est. completion 2009-08 25 sites Stand-aloneObstructive sleep apnea Other conditions: Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT00634933
Study Evaluating 2 Dosing Regimens Of TRU-015 In Rheumatoid Arthritis
Not yet reported Pfizer 222 participants Est. completion 2012-10 65 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Terminated NCT NCT00635726
Methotrexate, Vinblastine, Doxorubicin and Cisplatin (MVAC) Followed by Gemcitabine Plus Cisplatin (GEM+CDDP) in Locally Advanced or Metastatic Bladder Cancer
Not yet reported Hellenic Oncology Research Group 41 participants Est. completion 2013-02 7 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT00636909
Nonmyeloablative Allo SCT for the Treatment of Hematologic Disorders
Not yet reported Beth Israel Deaconess Medical Center 25 participants Stand-aloneOther conditions: AML, ALL, CML Chronic Phase, Accelerated Phase, or Blast Crisis, CLL, MDS, RELAPSED NON-HODGKIN'S OR HODGKIN'S LYMPHOMA, APLASTIC ANEMIA, MULTIPLE MYELOMA, MYELOPROLIFERATIVE DISORDER (P Vera, CMML, ET)View official trial listing → -
Completed NCT NCT00639834
Study of the Safety of MDX-1342 in Combination With Methotrexate in Patients With Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 26 participants Est. completion 2010-06 24 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00642460
A Study of RoActemra/Actemra (Tocilizumab) in Patients With Active Systemic Juvenile Idiopathic Arthritis (JIA)
Not yet reported Hoffmann-La Roche 112 participants Est. completion 2014-08 54 sites Stand-aloneOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT00645632
Combination Chemotherapy in Treating Patients Undergoing Surgery for Newly Diagnosed High-Grade Osteosarcoma
Not yet reported Mayo Clinic 60 participants Est. completion 2008-01Other conditions: SarcomaView official trial listing → -
Status unknown NCT NCT00647049
Freiburg ZNS-NHL Study
Not yet reported University Hospital Freiburg 78 participants Est. completion 2013-08 1 site Stand-aloneOther conditions: Primary Non Hodgkin Lymphoma of the Central Nervous SystemView official trial listing → -
Completed NCT NCT00647920
Study of Adalimumab Administered as Subcutaneous Injections in Adult Chinese Rheumatoid Arthritis Subjects Treated With Methotrexate
Not yet reported Abbott 47 participants 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00651040
Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM
Not yet reported Institute of Rheumatology, Prague 31 participants Est. completion 2014-11 1 siteOther conditions: Polymyositis, DermatomyositisView official trial listing → -
Completed NCT NCT00653068
Combination Chemotherapy, Radiation Therapy, and an Autologous Peripheral Blood Stem Cell Transplant in Treating Young Patients With Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System
Not yet reported Children's Oncology Group 70 participants Est. completion 2024-03-31 94 sites Stand-aloneOther conditions: Childhood Atypical Teratoid/Rhabdoid TumorView official trial listing → -
Completed NCT NCT00654368
CAMEO: Canadian Methotrexate and Etanercept Outcome Study
Not yet reported Amgen 258 participants Est. completion 2013-02 28 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00655343
Acute Graft-Versus-Host Disease (aGvHD) Prophylaxis With ATG-Fresenius in Matched Unrelated Donor-Stem Cell Transplantation (MUD-SCT)
Not yet reported Neovii Biotech 202 participants Est. completion 2009-03 1 site Stand-aloneOther conditions: Graft vs Host DiseaseView official trial listing → -
Status unknown NCT NCT00656591
Community-Based Interventions for Infant Health in Nepal
Institute of Child Health 192000 participants Est. completion 2008-12 1 siteOther conditions: Child MortalityView official trial listing → -
Completed NCT NCT00658047
A Study to Assess CH1504 in Patients With Active Rheumatoid Arthritis
Not yet reported Chelsea Therapeutics 201 participants Est. completion 2009-06 1 siteOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00659412
A Placebo-controlled Study With an Extension Examining the Safety and Efficacy of Alefacept in Psoriatic Arthritis
Not yet reported Astellas Pharma Inc 185 participants Est. completion 2005-03 27 sites Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT00660647
Optimized Treatment Algorithm for Patients With Early Rheumatoid Arthritis (RA)
Not yet reported University of Aarhus 180 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Terminated NCT NCT00664573
104RA204 Assessment of the Safety and Efficacy of BG9924 in Rheumatoid Arthritis (RA) Participants
Not yet reported Biogen 339 participants Est. completion 2008-10 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00664599
Rituximab for the Treatment of Severe Ocular Manifestations of Behcet's Disease
Not yet reported Tehran University of Medical Sciences 20 participants Est. completion 2008-01 1 site Stand-aloneOther conditions: Behcet's SyndromeView official trial listing → -
Completed NCT NCT00664716
Assessment Of The Safety And Efficacy Of BG9924 In Rheumatoid Arthritis (RA) Participants
Not yet reported Biogen 391 participants Est. completion 2008-10 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00665925
Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis
Not yet reported Rigel Pharmaceuticals 457 participants Est. completion 2009-06 65 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00666354
Dose Response and Safety Study of Topical Methotrexate for the Treatment of Fingernail Psoriasis
Not yet reported MediQuest Therapeutics 83 participants Est. completion 2009-01 7 sitesOther conditions: Fingernail PsoriasisView official trial listing → -
Completed NCT NCT00667342
A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma
Not yet reported St. Jude Children's Research Hospital 43 participants Est. completion 2017-08 5 sites Stand-aloneObstructive sleep apnea Other conditions: Malignant Fibrous Histiocytoma (MFH) of BoneView official trial listing → -
Completed NCT NCT00669877
Rituximab and Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) for Burkitt's and Burkitt's -Like Leukemia/Lymphoma
Not yet reported M.D. Anderson Cancer Center 56 participants Est. completion 2015-10 1 site Stand-aloneOther conditions: Burkitt's Lymphoma, Burkitt'S-like LymphomaView official trial listing → -
Completed NCT NCT00671034
Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 166 participants Est. completion 2021-03-31 27 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia, Childhood B Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00671658
Modified Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) Program for Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center 220 participants Est. completion 2013-07 1 site Stand-aloneOther conditions: Leukemia, Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00673101
Prospective Evaluation of FibroScan in Patients Treated With Methotrexate
Association HGE CHU Bordeaux Sud 1871 participants Est. completion 2019-07 1 siteOther conditions: Liver FibrosisView official trial listing → -
Terminated NCT NCT00673179
Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient Chemotherapy
Not yet reported M.D. Anderson Cancer Center 7 participants Est. completion 2010-11 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Terminated NCT NCT00673920
A Study to Evaluate Ocrelizumab Compared With Placebo in Patients With Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate Therapy
Not yet reported Genentech, Inc. 314 participants Est. completion 2009-10-26 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00679731
A Study of Safety and Efficacy Comparing ABT-874 Versus Methotrexate in Subjects With Moderate to Severe Plaque Psoriasis
Not yet reported AbbVie (prior sponsor, Abbott) 317 participants Est. completion 2009-11 43 sitesOther conditions: PsoriasisView official trial listing → -
Active, not recruiting NCT NCT00683319
Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy
Children's Cancer and Leukaemia Group 50 participants 10 sitesOther conditions: Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Long-term Effects Secondary to Cancer Therapy in Children, OtotoxicityView official trial listing → -
Completed NCT NCT00686868
Study to Evaluate SC Route of Administration of Ofatumumab in RA Patients
Not yet reported GlaxoSmithKline 35 participants Est. completion 2011-05-02 17 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT00687648
Cyclophosphamide, Methotrexate, and Prednisolone With or Without Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer
Not yet reported National Cancer Centre, Singapore 70 participants 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00688103
Efficacy and Safety of Etanercept in Active RA Despite Methotrexate Therapy in Japan
Not yet reported Japan Biological Agent Study Integrated Consortium 151 participants Est. completion 2010-10 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00689845
Combination Chemotherapy and Rituximab in Treating Patients With Primary Mediastinal Diffuse Large B-Cell Lymphoma
Not yet reported University Hospital Southampton NHS Foundation Trust 120 participants 8 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00695188
Methotrexate Polyglutamate Levels as a Marker for the Clinical Outcome in the Treatment of Rheumatoid Arthritis
Not yet reported Ludwig-Boltzmann Institut fuer Rheumatologie, Balneologie und Rehabilitation 19 participants Est. completion 2010-12 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00696735
High-Dose Therapy Treatment in Patients With Follicular Lymphoma
Not yet reported French Innovative Leukemia Organisation 172 participants Est. completion 2006-05 2 sites Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Terminated NCT NCT00697593
ChangE From Any Systemic psoriasiS therapY to Raptiva
Not yet reported Merck KGaA, Darmstadt, Germany 70 participants Est. completion 2009-04 1 siteOther conditions: Chronic Plaque PsoriasisView official trial listing → -
Completed NCT NCT00700544
Treatment Outcome in Elderly Patients
Not yet reported University Hospital, Grenoble 330 participants Est. completion 2008-05 1 site Stand-aloneOther conditions: AML, Elderly PatientsView official trial listing → -
Completed NCT NCT00701129
An Exploratory Study of the Safety and Efficacy of Prophylactic Immunomodulatory Treatment in Myozyme-naive Cross-Reacting Immunologic Material (CRIM[-]) Patients With Infantile-Onset Pompe Disease
Not yet reported Genzyme, a Sanofi Company 4 participants Est. completion 2013-03 2 sites Stand-aloneOther conditions: Pompe Disease, Glycogen Storage Disease Type IIView official trial listing → -
Terminated NCT NCT00701701
Immune Tolerance Induction Study
Not yet reported Genzyme, a Sanofi Company 4 participants Est. completion 2020-02-18 5 sites Stand-aloneOther conditions: Pompe Disease, Glycogen Storage Disease Type II (GSD-II), Glycogenesis 2 Acid Maltase DeficiencyView official trial listing → -
Terminated NCT NCT00706797
Study Evaluating Efficacy / Safety of Etanercept + Methotrexate Compared to Usual Treatment in Moderate RA Subjects
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 141 participants Est. completion 2010-05 45 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00707083
Two Combination Chemotherapy Regimens in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Prince of Wales Hospital, Shatin, Hong Kong 2231 participants Est. completion 2020-03-01 2 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00712114
Safety, Tolerance, Pharmacokinetics and Activity of HE3286 in Patients With Rheumatoid Arthritis
Not yet reported, Not yet reported Harbor Therapeutics 14 participants Est. completion 2009-07 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00713544
A Proof of Concept and Dose Ranging Study in Patients With Rheumatoid Arthritis
Not yet reported AstraZeneca 373 participants Est. completion 2009-04 49 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00716248
Bucillamine Study of Holding Remission After Infliximab Dose-off
Not yet reported Saitama Medical University 40 participants 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT00717808
Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA)
Not yet reported Imperial College London Est. completion 2009-09Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00718718
A Study of Effectiveness and Safety of CNTO 136 in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Centocor, Inc. 187 participants Est. completion 2011-03-03 38 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00720109
Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported National Cancer Institute (NCI) 63 participants Est. completion 2020-03-31 134 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1View official trial listing → -
Terminated NCT NCT00720629
Visilizumab for the Prevention of Graft-versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 8 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT00720798
An Extension Study of Tocilizumab (Myeloma Receptor Antibody [MRA]) in Patients Completing Treatment in Tocilizumab Core Studies
Not yet reported Hoffmann-La Roche 2067 participants Est. completion 2013-04 295 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00727831
Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
Not yet reported, Not yet reported University College, London 4 participants Est. completion 2011-07 2 sitesOther conditions: Chemotherapeutic Agent Toxicity, Lymphoma, Mucositis, NeurotoxicityView official trial listing → -
Completed NCT NCT00727987
A Safety and Efficacy Study of Golimumab (CNTO 148) in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Janssen Pharmaceutical K.K. 269 participants Est. completion 2011-12 65 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT00730717
Safety and Efficacy Study of Humira in Treatment of Pyoderma Gangrenosum
Not yet reported Wright State University Est. completion 2010-12 1 site Stand-aloneOther conditions: Pyoderma GangrenosumView official trial listing → -
Completed NCT NCT00732875
A Trial of Anti-TNF Chimeric Monoclonal Antibody (cA2) in Korean Patients With Active Rheumatoid Arthritis Despite Methorexate (Extension Part)(Study P05645)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 92 participants Est. completion 2008-05 Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Withdrawn NCT NCT00734773
Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL
Not yet reported Northwestern UniversityOther conditions: Brain and Central Nervous System Tumors, Lymphoma, NeurotoxicityView official trial listing → -
Completed NCT NCT00741455
Chemotherapy Followed by Allogeneic Stem Cell Transplantation for Hematologic Malignancies
Not yet reported Dartmouth-Hitchcock Medical Center 18 participants Est. completion 2020-05-01 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT00742924
Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma
Not yet reported Children's Oncology Group 24 participants 88 sites Stand-aloneOther conditions: SarcomaView official trial listing → -
Completed NCT NCT00745420
Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601)
Not yet reported Medical College of Wisconsin 30 participants Est. completion 2016-09 19 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT00747214
A Study Comparing CRx-102 Plus Disease-modifying Anti-rheumatic Drug (DMARD) Therapy to Placebo Plus DMARD Therapy in RA
Not yet reported Zalicus 59 participants Est. completion 2006-11 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00748826
Remicade Safety Line (Study P03236)(COMPLETED)
Merck Sharp & Dohme LLC 576 participants Est. completion 2010-12Other conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT00751517
Cyclophosphamide Versus Methotrexate for Remission Maintenance in Systemic Necrotizing Vasculitides
Not yet reported University of Parma 1 site Stand-aloneObstructive sleep apnea Other conditions: Wegener's Granulomatosis, Churg-Strauss Syndrome, Microscopic PolyangiitisView official trial listing → -
Completed NCT NCT00753454
Open Label Extension for Patients Coming From the Dosing Flexibility Study in Patients With Rheumatoid Arthritis (RA)
Not yet reported UCB Pharma 168 participants Est. completion 2011-05 40 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00754572
A Study to Assess the Effect of Tocilizumab Plus Methotrexate on Safety and Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 418 participants Est. completion 2012-10 69 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00759811
METhotrexate Therapy Effects in the Physical Capacity of Patients With ISchemic Heart Failure (METIS Trial)
Not yet reported, Not yet reported Instituto de Cardiologia do Rio Grande do Sul 50 participants Est. completion 2008-11 1 site Stand-aloneHeart failure Other conditions: Myocardial IschemiaView official trial listing → -
Completed NCT NCT00760669
An Observational Study of Infliximab Injection in Ankylosing Spondylitis, Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis Participants
Janssen Korea, Ltd., Korea 1061 participants Est. completion 2011-04Other conditions: Spondylitis, Ankylosing, Arthritis, Rheumatoid, Psoriasis, Arthritis, PsoriaticView official trial listing → -
Completed NCT NCT00760864
Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis
Not yet reported Takeda 432 participants Est. completion 2005-09 Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00760968
Efficacy and Safety of TAK-783 in Subjects With Rheumatoid Arthritis
Not yet reported Takeda 224 participants Est. completion 2009-02 25 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00764725
Comparison of MTX+Anti-TNF to MTX+Conventional DMARDs in Patients With Early Rheumatoid Arthritis (RA) Who Failed MTX Alone (SWEFOT)
Not yet reported Karolinska Institutet 487 participants Est. completion 2008-12Other conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00764907
Risk-Adjusted Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia
Not yet reported University Hospital, Motol 4000 participants 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00767325
A Rheumatoid Arthritis Study to Assess Early Response to Abatacept+MTX as Defined by Improvement of Synovitis Measures by Power Doppler Ultrasonography
Not yet reported Bristol-Myers Squibb 104 participants Est. completion 2011-10 21 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00775632
Alemtuzumab and Cyclosporine for the Prevention of Graft vs Host Disease After Stem Cell Transplants
Not yet reported University Health Network, Toronto 78 participants Est. completion 2010-09 1 siteOther conditions: Graft Versus Host Disease, Bone Marrow TransplantationView official trial listing → -
Terminated NCT NCT00779142
Utility of Intravitreal Methotrexate in Diabetic Macular Edema Resistant to Conventional Therapies
Not yet reported Wake Forest University 2 participants Est. completion 2012-08 1 siteOther conditions: Diabetic Macular EdemaView official trial listing → -
Terminated NCT NCT00779220
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics/Pharmacodynamics (PK/PD) of Ocrelizumab in Patients With Rheumatoid Arthritis
Not yet reported Chugai Pharmaceutical 152 participants Est. completion 2015-03 7 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00781469
A Study to Evaluate the RNA Signature of Rheumatoid Arthritis From Synovium and Whole Blood
Imperial College London 29 participants Est. completion 2010-10 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00783510
Juvenile Idiopathic Arthritis (JIA) Registry
AbbVie 849 participants Est. completion 2024-02-01 92 sitesOther conditions: Juvenile Idiopathic Arthritis, JIAView official trial listing → -
Withdrawn NCT NCT00783536
A Multicenter Study to Compare the Efficacy and Safety of the Combination of Etanercept and Methotrexate in Treatment of Rheumatoid Arthritis
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer Est. completion 2010-06 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00785928
A Study for Patients With Active Rheumatoid Arthritis Despite Ongoing Methotrexate Therapy
Not yet reported Eli Lilly and Company 158 participants Est. completion 2010-12 48 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00787761
Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer
Not yet reported Northside Hospital, Inc. 24 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00791531
Assessment of Safety and Pharmacokinetics of a Low Dose of Methotrexate in Healthy Adult Male Kenyan Volunteers
Not yet reported KEMRI-Wellcome Trust Collaborative Research Program 25 participants Est. completion 2009-08 1 site Stand-aloneOther conditions: MalariaView official trial listing → -
Completed NCT NCT00791921
Efficacy Confirmation Trial of CDP870 Without Coadministration of Methotrexate (MTX) in Japanese Rheumatoid Arthritis (RA)
Not yet reported Otsuka Pharmaceutical Co., Ltd. 230 participants Est. completion 2010-01 7 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00791999
Efficacy Confirmation Trial of CDP870 as add-on Medication to Methotrexate (MTX) in Japanese Rheumatoid Arthritis (RA)
Not yet reported, Not yet reported Otsuka Pharmaceutical Co., Ltd. 316 participants Est. completion 2011-01 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT00792948
Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 97 participants Est. completion 2027-01-06 157 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Adult L1 Acute Lymphoblastic Leukemia, Adult L2 Acute Lymphoblastic Leukemia, Adult T Acute Lymphoblastic Leukemia, Recurrent Adult Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00794898
Efficacy of Remicade in the Treatment of Active Rheumatoid Arthritis Despite Methotrexate (Study P03027)
Not yet reported Merck Sharp & Dohme LLC 19 participants Est. completion 2004-04-01Other conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00795756
Intrathecal DepoCyte and Lineage-targeted Minimal Residual Disease-oriented Therapy of Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported Northern Italy Leukemia Group 145 participants Est. completion 2013-10 16 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00796809
Risk of Coccidioidomycosis in Patients Receiving Anti-TNF and Other Biologic Agents for an Inflammatory Arthritis
University of Arizona 598 participants Est. completion 2008-10 1 siteOther conditions: Coccidioidomycosis, Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00801216
High-dose Sequential Chemoimmunotherapy for B-cell Lymphomas With Central Nervous System Involvement
Not yet reported Andrés José Maria Ferreri 40 participants Est. completion 2013-01 1 site Stand-aloneOther conditions: B-cell LymphomasView official trial listing → -
Status unknown NCT NCT00801580
My-HyperCVAD in the Treatment of Relapsed Refractory Adult Acute Lymphoid Leukemia
Not yet reported University of Bologna 3 participants Est. completion 2010-09 1 site Stand-aloneOther conditions: Lymphoid LeukemiaView official trial listing → -
Completed NCT NCT00803010
Graft-Versus-Host Disease (GVHD) Prophylaxis After Allogeneic Peripheral Blood Hematopoietic Cell Transplantation
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 74 participants Est. completion 2012-12 1 siteOther conditions: Acute Graft Versus Host DiseaseView official trial listing → -
Terminated NCT NCT00808210
A Study to Evaluate Ocrelizumab in Combination With Methotrexate Compared With Infliximab Plus Methotrexate in Patients With Active Rheumatoid Arthritis Currently Responding Inadequately to Etanercept or Adalimumab
Not yet reported Genentech, Inc. 28 participants Est. completion 2012-11-14 53 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00808509
A Pilot Study of the Feasibility of Discontinuation of Adalimumab in Stable Rheumatoid Arthritis Patients in Clinical Remission
Not yet reported AbbVie (prior sponsor, Abbott) 33 participants Est. completion 2012-09 8 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00808639
Dose-Dense MVAC With Pegfilgrastim Support in Subjects With Muscle-Invasive Urothelial Carcinoma
Not yet reported Dana-Farber Cancer Institute 39 participants Est. completion 2016-09 4 sites Stand-aloneOther conditions: Bladder Cancer, Muscle-invasive Bladder CancerView official trial listing → -
Completed NCT NCT00809172
Study of Methotrexate Efficacy Versus Cyclosporine in Moderate to Severe Atopic Dermatitis Patients
Not yet reported Hospices Civils de Lyon 100 participants Est. completion 2012-04 1 site Stand-aloneOther conditions: Atopic DermatitisView official trial listing → -
Completed NCT NCT00810199
A Study of Tocilizumab and Methotrexate Treatment Strategies (Adding Tocilizumab to Methotrexate Versus Switching to Tocilizumab) in Patients With Active Rheumatoid Arthritis With Inadequate Response to Prior Methotrexate Treatment
Not yet reported Hoffmann-La Roche 556 participants Est. completion 2013-01 137 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00810836
Efficacy and Safety Study of BG00012 With Methotrexate in Patients With Active Rheumatoid Arthritis
Not yet reported Biogen 153 participants Est. completion 2010-03 24 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00813124
Azacitidine After Allo Blood And Marrow Transplantation (BMT) for Chronic Myelogenous Leukemia (CML)
Not yet reported M.D. Anderson Cancer Center 24 participants Est. completion 2014-09 1 siteOther conditions: Stem Cell Transplantation, LeukemiaView official trial listing → -
Completed NCT NCT00814138
Efficacy of Methotrexate in Myasthenia Gravis
Not yet reported University of Kansas Medical Center 50 participants Est. completion 2014-01 16 sitesOther conditions: Myasthenia GravisView official trial listing → -
Terminated NCT NCT00818961
Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Cancer
Not yet reported Northside Hospital, Inc. 36 participants Est. completion 2012-03 1 siteOther conditions: Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00819351
ALL2008 Protocol for Childhood Acute Lymphoblastic Leukemia Intermittent Versus Continuous PEG Asparaginase
Not yet reported Copenhagen University Hospital, Rigshospitalet 650 participants Est. completion 2016-03-02 6 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00822432
Coproporphyrine Isomers and Methotrexate Elimination
Assistance Publique - Hôpitaux de Paris 85 participants Est. completion 2011-08 2 sitesOther conditions: Central Nervous System Neoplasms, Lymphoma, Large B-Cell, Diffuse, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Burkitt LymphomaView official trial listing → -
Terminated NCT NCT00833053
Dose Optimization of Infliximab in Moderate to Severe Plaque Psoriasis (Study P05315)
Not yet reported Merck Sharp & Dohme LLC 39 participants Est. completion 2011-04 Stand-aloneOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT00838565
Phase I Study Of The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Multiple Intravenously Administered Doses Of PF-04236921 In Patients With Rheumatoid Arthritis
Not yet reported Pfizer 41 participants Est. completion 2012-02-02 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00844298
Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Asan Medical Center 91 participants Est. completion 2014-07 16 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00845832
A Study of Combination Treatment With MabThera (Rituximab) and RoActemra (Tocilizumab) Versus RoActemra in Patients With Rheumatoid Arthritis With an Incomplete Response to Methotrexate
Not yet reported Hoffmann-La Roche 24 participants Est. completion 2013-03 24 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00846703
The GD-2008 ALL Protocol for Childhood Acute Lymphoblastic Leukemia
Not yet reported Sun Yat-sen University 600 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00847613
A 2-Year Phase 3 Study Of CP-690,550 In Patients With Active Rheumatoid Arthritis On Background Methotrexate
Not yet reported Pfizer 800 participants Est. completion 2012-02 115 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00847886
Study of LX3305 and Methotrexate in Subjects With Stable Rheumatoid Arthritis
Not yet reported Lexicon Pharmaceuticals 15 participants Est. completion 2009-03 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00848354
Open-Label Study Comparing Etanercept to Conventional Disease Modifying Antirheumatic Drug (DMARD) Therapy
Not yet reported Pfizer 429 participants Est. completion 2013-04 33 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00850343
Long-term Treatment Study of Certolizumab Pegol Without Coadministration of Methotrexate in Japanese Rheumatoid Arthritis (RA) Patients
Not yet reported Astellas Pharma Inc 208 participants Est. completion 2013-05 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00851318
Long-term Treatment Study of Certolizumab Pegol (CDP870) as Add-on Medication to Methotrexate in Japanese Rheumatoid Arthritis (RA) Patients
Not yet reported Astellas Pharma Inc 285 participants Est. completion 2013-06 8 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00853008
Treatment of High Risk Adult Acute Lymphoblastic Leukemia
Not yet reported PETHEMA Foundation 100 participants Est. completion 2012-12 38 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00853385
A Phase 3 Study Comparing 2 Doses Of CP-690,550 And The Active Comparator, Humira (Adalimumab) Vs. Placebo For Treatment Of Rheumatoid Arthritis
Not yet reported Pfizer 717 participants Est. completion 2011-03 125 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00854685
Dose Optimisation Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate
Not yet reported Arana Therapeutics Ltd 27 participants Est. completion 2010-01 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00858780
Study Comparing The Effect On Disease Activity When Reducing Or Discontinuing Etanercept In Subjects With RA
Not yet reported Pfizer 91 participants Est. completion 2012-06 16 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00860574
Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia
Not yet reported Fred Hutchinson Cancer Center 96 participants 3 sites Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Blastic Phase Chronic Myelogenous Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT00863460
Cranial Radiotherapy or Intensive Chemotherapy With Hematopoietic Stem Cell Rescue for Primary Central Nervous System Lymphoma in Young Patients
Not yet reported Institut Curie 140 participants Est. completion 2026-05 23 sitesOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT00866307
Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia (Closed to Accrual 4-22-2011)
Not yet reported Children's Oncology Group 104 participants Est. completion 2021-03-31 28 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia, Childhood B Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00866749
Augmented Berlin-Frankfurt-Munster (BFM) Therapy for Adolescent/Young Adults With Acute Lymphoblastic Leukemia or Acute Lymphoblastic Lymphoma
Not yet reported M.D. Anderson Cancer Center 120 participants Est. completion 2018-07-26 1 site Stand-aloneOther conditions: Lymphoblastic Leukemia, Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT00866918
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia
Not yet reported Children's Oncology Group 106 participants Est. completion 2022-09-30 121 sites Stand-aloneOther conditions: Childhood Acute Promyelocytic Leukemia With PML-RARA, Myeloid NeoplasmView official trial listing → -
Completed NCT NCT00867516
Safety, Efficacy and Pharmacokinetics Study of ALD518 in Patients With Active Rheumatoid Arthritis
Not yet reported CSL Behring 127 participants Est. completion 2009-12 26 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00870467
A Study of Adalimumab in Japanese Subjects With Rheumatoid Arthritis
Not yet reported Abbott 334 participants Est. completion 2011-08 88 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00873093
Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Not yet reported National Cancer Institute (NCI) 148 participants Est. completion 2014-09 171 sites Stand-aloneOther conditions: B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Lymphoblastic Lymphoma, T-cell Adult Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00880815
Fludarabine, Bendamustine, and Rituximab in Treating Participants With Lymphoid Cancers Undergoing Stem Cell Transplant
Not yet reported M.D. Anderson Cancer Center 60 participants Est. completion 2019-05-28 1 site Stand-aloneOther conditions: CD20 Positive, Chronic Lymphocytic Leukemia, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, T-Cell Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT00882024
Safety and Efficacy Study of Tranilast in Patients With Active Rheumatoid Arthritis (RA)
Not yet reported Nuon Therapeutics, Inc. 250 participants Est. completion 2010-12 32 sitesOther conditions: Active Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00882206
Pre-reinductive Decitabine and Vorinostat in Relapsed Lymphoblastic Lymphoma or Acute Lymphoblastic Leukemia
Not yet reported Masonic Cancer Center, University of Minnesota 15 participants Est. completion 2013-01 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00890656
Study of Augmented Hyper-CVAD in Acute Lymphoblastic Leukemia Salvage
Not yet reported M.D. Anderson Cancer Center 90 participants Est. completion 2011-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00896168
An Efficacy and Safety Study of Infliximab in Participants With Rheumatoid Arthritis
Not yet reported Xian-Janssen Pharmaceutical Ltd. 234 participants Est. completion 2008-04 Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00898404
Response or Resistance to Chemotherapy in Young Patients With Acute Lymphoblastic Leukemia Treated With Methotrexate
Children's Oncology Group 150 participants Est. completion 2016-05 1 siteOther conditions: B-cell Childhood Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Recurrent Childhood Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00899899
Resistance to Methotrexate in Patients With Acute Lymphoblastic Leukemia in Relapse or Remission
Children's Oncology Group 135 participants Est. completion 2006-04Other conditions: LeukemiaView official trial listing → -
Completed NCT NCT00901550
The Chinese University of Hong Kong Early Arthritis Study
Not yet reported Chinese University of Hong Kong 40 participants Est. completion 2011-10 3 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00903383
Study of LX3305 in Subjects With Active Rheumatoid Arthritis on Stable Methotrexate
Not yet reported Lexicon Pharmaceuticals 208 participants 38 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00905034
Methotrexate, Vincristine, Pegylated L-Asparaginase and Dexamethasone (MOAD) in Acute Lymphoblastic Leukemia (ALL) Salvage
Not yet reported M.D. Anderson Cancer Center 37 participants Est. completion 2015-02 1 site Stand-aloneOther conditions: Leukemia, Lymphocytic, AcuteView official trial listing → -
Completed NCT NCT00905073
Low Dose Cyclosporin and Methotrexate Therapy in Diabetes
Not yet reported Georgetown University 8 participants Est. completion 1994-06 1 site Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT00908089
TNF-blocking Therapy in Combination With Disease-modifying Antirheumatic Drugs in Early Rheumatoid Arthritis
Not yet reported University of Helsinki 100 participants Est. completion 2015-12 13 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00912223
Blood Stem Cell Transplant With Low Dose Chemotherapy for Relapsed Follicular Non-Hodgkin's Lymphoma (BMT CTN 0701)
Not yet reported Medical College of Wisconsin 65 participants Est. completion 2016-08 21 sites Stand-aloneOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Completed NCT NCT00913432
Masitinib in Combination With Methotrexate, in Treatment of Patients With Active Rheumatoid Arthritis
Not yet reported AB Science 20 participants Est. completion 2010-09Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00913458
Study Evaluating Etanercept Plus Methotrexate in Early Rheumatoid Arthritis
Not yet reported Pfizer 306 participants Est. completion 2012-12 59 sites Stand-aloneOther conditions: Active Rheumatoid Arthritis, Arthritis, Rheumatoid, Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00918554
Efficacy Study of Methotrexate to Treat Sarcoid-associated Uveitis
Not yet reported Assistance Publique - Hôpitaux de Paris 7 participants Est. completion 2010-08 2 sites Stand-aloneOther conditions: Sarcoid-associated Uveitis, Ocular Sarcoidosis, Macular EdemaView official trial listing → -
Completed NCT NCT00919503
Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders
Not yet reported Fred Hutchinson Cancer Center 98 participants Est. completion 2020-06-10 6 sites Stand-aloneOther conditions: Non-Neoplastic Hematologic and Lymphocytic DisorderView official trial listing → -
Withdrawn NCT NCT00920608
A Study to Assess the Pharmacokinetics of Methotrexate Given With and Without AZD9056 in Rheumatoid Arthritis Patients
Not yet reported AstraZeneca 12 participants Est. completion 2009-09 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00925652
Bevacizumab, Metronomic Chemotherapy (CM), Diet and Exercise After Preoperative Chemotherapy for Breast Cancer
Not yet reported Dana-Farber Cancer Institute 55 participants Est. completion 2019-01-30 9 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00928018
Tacrolimus/Sirolimus/Methotrexate vs Tacrolimus/Methotrexate or Cyclosporine/Mycophenolate Mofetil for GVHD Prophylaxis After Reduced Intensity Allogeneic Stem Cell Transplantation for Patients With Lymphoma
Not yet reported Dana-Farber Cancer Institute 139 participants Est. completion 2014-11 5 sitesOther conditions: Non-hodgkin Lymphoma, Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT00928200
Erwinase for Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) (IND 104224)
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 1 participants Est. completion 2010-06-04 1 site Stand-aloneOther conditions: Relapsed Acute Lymphoblastic Leukemia, Allergy to PEG e.Coli Asparaginase, Allergy to Native e.Coli AsparaginaseView official trial listing → -
Terminated NCT NCT00928317
Dose Ranging Study of ART621 in Subjects Diagnosed With Rheumatoid Arthritis Taking Methotrexate
Not yet reported Arana Therapeutics Ltd 13 participants Est. completion 2009-12 46 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00928512
Efficacy, Safety and Tolerability of AIN457 in Patients With Rheumatoid Arthritis (RA) Taking Methotrexate (MTX)
Not yet reported Novartis Pharmaceuticals 237 participants Est. completion 2011-03 58 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00929864
Abatacept Versus Adalimumab Head-to-Head
Not yet reported Bristol-Myers Squibb 869 participants Est. completion 2012-11 83 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00931957
Etanercept: Single Blind Control Study in Ocular Manifestations of Behcet's Disease
Not yet reported Tehran University of Medical Sciences 80 participants Est. completion 2013-10 1 siteOther conditions: Behcet Syndrome, Uveal DiseaseView official trial listing → -
Completed NCT NCT00932113
Mechanism of Action Study for Psoriasis
Not yet reported Tufts Medical Center 33 participants Est. completion 2017-05-01 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT00934648
A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Methotrexate
Not yet reported Hoffmann-La Roche 15 participants Est. completion 2010-11 5 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00940524
Induction Therapy With Cytarabine, High-Dose Mitoxantrone and Dasatinib for Patients With Philadelphia-Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 7 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Leukemia, Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT00941707
An Efficacy and Safety Study of JNJ-38518168 in Adult Participants With Rheumatoid Arthritis
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 86 participants Est. completion 2010-11 34 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00945724
Safety and Feasibility Study of Combination of State of Art Chemoimmunotherapy, Intensive Central Nervous System Prophylaxis and Scrotal Irradiation to Treat Primary Diffuse Large B-cell Lymphoma of Testis
Not yet reported International Extranodal Lymphoma Study Group (IELSG) 54 participants Est. completion 2023-09-26 22 sites Stand-aloneOther conditions: Large B-cell Diffuse Lymphoma of TestisView official trial listing → -
Completed NCT NCT00945815
S0910 Epratuzumab, Cytarabine, and Clofarabine in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported SWOG Cancer Research Network 35 participants Est. completion 2017-08 81 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00948753
Maraviroc in Patients Undergoing Non-Myeloablative Allogeneic Stem-Cell Transplantation
Not yet reported, Not yet reported Abramson Cancer Center at Penn Medicine 38 participants Est. completion 2011-04 Stand-aloneOther conditions: Graft-versus-host Disease, Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT00950989
Brodalumab (AMG 827) in Rheumatoid Arthritis (RA) Participants With Inadequate Response to Methotrexate
Not yet reported Amgen 252 participants Est. completion 2011-02-11 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00952016
Methotrexate in Metastatic Colorectal Cancer With MSH2 Deficiency
Not yet reported Royal Marsden NHS Foundation Trust 2 participants Est. completion 2014-09 1 siteOther conditions: Advanced Colorectal CancerView official trial listing → -
Withdrawn NCT NCT00957320
Study of Sirolimus With PEG-Asparaginase in Acute Lymphoblastic Leukemia (ALL)
Not yet reported Emory University Est. completion 2012-08 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00959036
Study Evaluating Multiple Doses Of ATN-103 In Subjects With Active Rheumatoid Arthritis
Not yet reported, Not yet reported Ablynx, a Sanofi company 252 participants Est. completion 2011-01 67 sites Stand-aloneOther conditions: Active Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00960440
Study of CP-690,550 Versus Placebo In Rheumatoid Arthritis Patients On Background Methotrexate With Inadequate Response To Tumor Necrosis Factor (TNF) Inhibitors
Not yet reported Pfizer 399 participants Est. completion 2011-03 92 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00962767
Comparison of Two Treatments in Intermediate and High-risk Acute Promyelocytic Leukemia (APL) Patients to Assess Efficacy in 1st Hematological Complete Remission and Molecular Remission
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 168 participants Est. completion 2007-12Other conditions: Leukemia, Myelocytic, AcuteView official trial listing → -
Completed NCT NCT00965289
High-dose Chemotherapy With Rituximab for Adults With Aggressive Large B-cell Lymphoma
Not yet reported Nantes University Hospital 42 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: B-Cell LymphomaView official trial listing → -
Completed NCT NCT00965653
A Study of Subcutaneously Administered Tocilizumab in Patients With Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 29 participants Est. completion 2011-07 7 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00965757
A Multicenter, Randomized, Double-blind, Placebo-controlled Study of the Combination Therapy of T-614 and Methotrexate in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate
Not yet reported Eisai Co., Ltd. 253 participants Est. completion 2011-09-30 72 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00967057
Combination Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported Children's Cancer and Leukaemia Group 470 participants Est. completion 2011-12 6 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00968253
RAD001 Study in Treatment of Relapsed or Refractory Acute Lymphocytic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 24 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: Leukemia, Acute Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT00972660
Safety and Efficacy Study of Allogenic Mesenchymal Stem Cells to Treat Extensive Chronic Graft Versus Host Disease
Not yet reported Guangdong Provincial People's Hospital 52 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT00973479
An Effectiveness and Safety Study of Intravenous Golimumab in Patients With Active Rheumatoid Arthritis Despite Treatment With Methotrexate Therapy
Not yet reported Centocor, Inc. 592 participants Est. completion 2013-02 88 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT00973752
Treatment of Older Adults With Acute Lymphoblastic Leukemia
Not yet reported Massachusetts General Hospital 30 participants Est. completion 2016-04 3 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT00974792
Combination Chemotherapy and Rituximab in Treating Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma
Not yet reported Cancer Research UK 150 participants 1 siteOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00976599
A Study To Evaluate The Mechanism Of Action Of CP-690,550 In Patients With Rheumatoid Arthritis
Not yet reported Pfizer 29 participants Est. completion 2011-07 15 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT00981799
Trial of Nelarabine, Etoposide and Cyclophosphamide in Relapsed T-cell ALL and T-cell LL
Not yet reported, Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 23 participants Est. completion 2016-07-18 37 sites Stand-aloneOther conditions: Relapsed T-Cell Acute Lymphoblastic Leukemia, Relapsed T-Cell Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT00987831
Biomarkers of Lupus Disease: Serial Biomarker Sampling in Patients With Active Systemic Lupus Erythematosus (SLE)
Not yet reported, Not yet reported Oklahoma Medical Research Foundation 158 participants Est. completion 2012-12 2 sites Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Completed NCT NCT00989235
Substudy - Low Dose of Abatacept in Subjects With Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 108 participants Est. completion 2009-10Other conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT00989352
Methotrexate-based Chemo-immunotherapy Followed by Maintenance Therapy for Patients > 65 Years With Central Nervous System (CNS)-Lymphoma
Not yet reported University Hospital Freiburg 56 participants Est. completion 2011-09 1 siteOther conditions: Primary Non Hodgkin Lymphoma of the Central Nervous SystemView official trial listing → -
Completed NCT NCT00989703
GLPG0259 Multiple Ascending Dose and Methotrexate Drug-drug Interaction (DDI) in Healthy Subjects
Not yet reported Lakefront Biotherapeutics NV 24 participants Est. completion 2010-01 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00991133
A Safety and Tolerability Study of Clofarabine, Etoposide, Cyclophosphamide, PEG-asparaginase, and Vincristine in Pediatric Acute Lymphoblastic Leukemia (ALL)
Not yet reported Genzyme, a Sanofi Company 8 participants Est. completion 2011-04 6 sites Stand-aloneOther conditions: Lymphoblastic Leukemia, Acute, ChildhoodView official trial listing → -
Suspended NCT NCT00991744
Liposomal Cytarabine for Central Nervous System (CNS)-Treatment in High-risk Acute Lymphoblastic Leukemia (ALL)
Not yet reported Nordic Society for Pediatric Hematology and Oncology 100 participants Est. completion 2018-12 5 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00992602
Liposomal Cytarabine and High-Dose Methotrexate in Treating Patients With Central Nervous System Metastases From Breast Cancer
Not yet reported University of Washington 3 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: Central Nervous System Metastases, Leptomeningeal Metastases, Recurrent Breast Cancer, Stage IV Breast Cancer, Tumors Metastatic to BrainView official trial listing → -
Completed NCT NCT00993135
Kidney Dysfunction in Children and Young Adults Who Have Received Methotrexate for Acute Lymphoblastic Leukemia
Vanderbilt University Medical Center 10 participants 2 sitesOther conditions: Leukemia, Renal ToxicityView official trial listing → -
Completed NCT NCT00993317
A Study of CDP870 as Add-on Meditation to Methotrexate (MTX) in Patients With Rheumatoid Arthritis
Not yet reported Korea Otsuka Pharmaceutical Co., Ltd. 127 participants Est. completion 2011-08 15 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00993343
Randomized Trial Comparing Sirolimus and Tacrolimus Versus Cyclosporine and Methotrexate as Graft-versus-host Disease (GVHD) Prophylaxis After Allogeneic Stem Cell Transplantation
Not yet reported Karolinska Institutet 215 participants Est. completion 2015-04 1 siteOther conditions: Graft-versus-host Disease, SurvivalView official trial listing → -
Completed NCT NCT01000610
A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Not yet reported Hoffmann-La Roche 18 participants Est. completion 2012-05-16 4 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01001208
The Efficacy and Safety of Adding Methotrexate to Etanercept in Psoriasis
Not yet reported Amgen 478 participants Est. completion 2011-02 Stand-aloneOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT01001832
Efficacy, Pharmacokinetics, Safety, and Immunogenicity Study of Abatacept Administered Subcutaneously to Treat Rheumatoid Arthritis in Japanese Patients
Not yet reported, Not yet reported Bristol-Myers Squibb 118 participants Est. completion 2012-10 33 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01004432
Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)
Not yet reported Janssen Biotech, Inc. 433 participants Est. completion 2013-10 117 sites Stand-aloneOther conditions: Arthritis, Arthritis, Rheumatoid, Autoimmune DiseasesView official trial listing → -
Status unknown NCT NCT01005758
Combination Chemotherapy in Treating Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Ohio State University Comprehensive Cancer Center 180 participantsOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT01005914
Pegaspargase and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported OHSU Knight Cancer Institute 11 participants Est. completion 2014-05 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT01007175
Study Evaluating Multiple Ascending Doses Of ATN-103 In Japanese Subjects With Rheumatoid Arthritis
Not yet reported, Not yet reported Ablynx, a Sanofi company 60 participants Est. completion 2010-09 15 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01007435
A Study of Tocilizumab as Monotherapy and in Combination With Methotrexate Versus Methotrexate in Patients With Early Moderate to Severe Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 1162 participants Est. completion 2014-01-28 236 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01008852
Study Evaluating The Efficacy And Safety Of SBI-087 In Seropositive Subjects With Active Rheumatoid Arthritis
Not yet reported Pfizer 210 participants Est. completion 2013-07 55 sites Stand-aloneOther conditions: Active Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01009242
To Evaluate the Blood Levels and Safety of IV and Subcutaneous CDP6038 in Subjects With Rheumatoid Arthritis Using Methotrexate
Not yet reported, Not yet reported UCB Pharma 40 participants Est. completion 2010-09 6 sites Stand-aloneOther conditions: Arthritis, Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01010503
A Study of Tocilizumab With or Without Methotrexate in Patients With Rheumatoid Arthritis.
Not yet reported Hoffmann-La Roche 32 participants Est. completion 2010-05 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01010581
SC12267 (4SC-101) in Combination With Methotrexate in Patients With Rheumatoid Arthritis
Not yet reported 4SC AG 266 participants Est. completion 2011-07 27 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01011920
Trial for Patients With Newly Diagnosed Primary Central Nervous System (CNS) Lymphoma
Not yet reported International Extranodal Lymphoma Study Group (IELSG) 227 participants Est. completion 2024-12-19 54 sites Stand-aloneOther conditions: Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT01011959
A Multiple-dose Study of the Safety and Tolerability of REGN88(SAR153191) in Rheumatoid Arthritis Subjects
Not yet reported Regeneron Pharmaceuticals 60 participants Est. completion 2009-08 24 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01012492
Pilot of Abatacept-based Immunosuppression for Prevention of Acute GvHD During Unrelated Donor HCT
Not yet reported Boston Children's Hospital 11 participants Est. completion 2013-01 1 site Stand-aloneOther conditions: AML, ALL, Undifferentiated Leukemia, Biphenotypic Leukemia, Refractory Anemia, Refractory Anemia With Ringed Sideroblasts, Refractory Cytopenia With Multilineage Dysplasia, Ref. Cytopenia w Multilineage Dysplasia & Ringed Sideroblasts, Refractory Anemia With Excess Blasts-1 (5-10% Blasts), Refractory Anemia With Excess Blasts-2 (10-20% Blasts), Myelodysplastic Syndrome, Unclassified, MDS Associated With Isolated Del (5q)View official trial listing → -
Terminated NCT NCT01014767
Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors
Not yet reported Tufts Medical Center 27 participants Est. completion 2014-01 5 sites Stand-aloneOther conditions: Brain Cancer, Choroid Plexus TumorsView official trial listing → -
Completed NCT NCT01015547
Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic Arthritis
Not yet reported Helsinki University Central Hospital 60 participants Est. completion 2013-12 6 sites Stand-aloneOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT01017367
Study of MDX-1100 (Anti-CXCL10 Human Monoclonal Antibody) in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (RA)
Not yet reported Bristol-Myers Squibb 70 participants Est. completion 2009-05 18 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01020539
Allogeneic Stem Cell Transplantation Followed By Targeted Immune Therapy In Average Risk Leukemia
Not yet reported Columbia University 18 participants Est. completion 2020-12 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Juvenile Myelomonocytic LeukemiaView official trial listing → -
Completed NCT NCT01020734
Donor Stem Cell Transplant or Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia in Remission
Not yet reported Asan Medical Center 263 participants Est. completion 2015-07 2 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT01026519
A Safety and Tolerability Study of REGN88(SAR153191) in Subjects With Rheumatoid Arthritis
Not yet reported Regeneron Pharmaceuticals 32 participants Est. completion 2009-05 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01027000
Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported Alliance for Clinical Trials in Oncology 68 participants Est. completion 2023-04 25 sites Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT01027702
Donor Lymphocyte Infusion After Alternative Donor Transplantation
Not yet reported, Not yet reported Wake Forest University Health Sciences 38 participants Est. completion 2016-11 1 siteOther conditions: ImmunodeficiencyView official trial listing → -
Status unknown NCT NCT01031030
Cyclophosphamide, Methotrexate, and Fluorouracil, With or Without Epirubicin Hydrochloride, in Treating Women Who Have Undergone Surgery for Breast Cancer (Group III Closed to New Patients as of 12/7/2009)
Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 800 participantsOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01031420
Dose Dense MVAC for Muscle Invasive Bladder Cancer
Not yet reported Fox Chase Cancer Center 54 participants Est. completion 2013-08-07 2 sites Stand-aloneOther conditions: Muscle Invasive Bladder Cancer, High Risk Urothelial Carcinoma of the Upper Urinary TractsView official trial listing → -
Completed NCT NCT01033656
Treatment of Refractory Adult-onset Still's Disease With Anakinra: a Randomized Study
Not yet reported University of Helsinki 23 participants Est. completion 2010-04 1 siteOther conditions: Adult-Onset Still's DiseaseView official trial listing → -
Completed NCT NCT01034137
A Study of Tocilizumab and Methotrexate in Combination or as Monotherapy in Treatment-Naïve Patients With Early Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 317 participants Est. completion 2014-09 21 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01038349
Applications for Methotrexate Optimization in Rheumatoid Arthritis
Cypress Bioscience, Inc. 256 participants Est. completion 2010-02Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01039688
Comparing The Effectiveness And Safety Of 2 Doses Of An Experimental Drug, CP-690,550, To Methotrexate (MTX) In Patients With Rheumatoid Arthritis Who Have Not Previously Received MTX
Not yet reported Pfizer 956 participants Est. completion 2013-03 176 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT01040195
Combination Disease-Modifying Antirheumatic Drugs (DMARDs) Versus Sulfasalazine in Inflammatory Back Pain
Not yet reported Sanjay Gandhi Postgraduate Institute of Medical Sciences 33 participants Est. completion 2012-12 1 siteOther conditions: Seronegative SpondyloarthropathiesView official trial listing → -
Completed NCT NCT01050998
A Study to Evaluate the Efficacy and Safety of CAM-3001 (Drug) in Subjects With Rheumatoid Arthritis
Not yet reported MedImmune LLC 516 participants Est. completion 2012-07-27 55 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01056614
Fludarabine Phosphate, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Peripheral Blood Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Malignancies
Not yet reported Fred Hutchinson Cancer Center 23 participants Est. completion 2016-04 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Blastic Phase Chronic Myelogenous Leukemia, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Chronic Phase Chronic Myelogenous Leukemia, de Novo Myelodysplastic Syndromes, Hematopoietic/Lymphoid Cancer, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Relapsing Chronic Myelogenous LeukemiaView official trial listing → -
Terminated NCT NCT01059448
Safety and Efficacy of AMG 827 in Subjects With RA
Not yet reported Amgen 211 participants Est. completion 2011-04-05 44 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01059773
A Safety and Efficacy Study of Ustekinumab in Patients With Plaque Psoriasis Who Have Had an Inadequate Response to Methotrexate
Not yet reported Janssen-Cilag International NV 490 participants Est. completion 2011-08 76 sites Stand-aloneOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT01063062
A Study With Tocilizumab [RoActemra/Actemra] Monotherapy or in Combination With Methotrexate in Patients With Rheumatoid Arthritis (PICTURE)
Not yet reported Hoffmann-La Roche 107 participants Est. completion 2011-01-17 9 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01067989
Low-Dose/Metronomic(LDM)Chemotherapy for Metastatic Breast Cancer
Not yet reported HaEmek Medical Center, Israel 22 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Chemotherapy, Breast Cancer, MetastaticView official trial listing → -
Completed NCT NCT01068405
Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo
Not yet reported Centre Hospitalier Universitaire de Nice 64 participants Est. completion 2018-10-15 1 site Stand-aloneOther conditions: PolyarthritisView official trial listing → -
Completed NCT NCT01079988
Study of Therapeutic Options for Subjects Discontinuing Efalizumab and Experiencing Disease Recurrence
Not yet reported Merck KGaA, Darmstadt, Germany 41 participants Est. completion 2005-04 Stand-aloneOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT01083342
High-Dose (HD) Methotrexate (MTX) Induction Chemotherapy Followed by Alternative HD MTX-based and HD Cytarabine-based Combination Consolidation Chemotherapy for Newly Diagnosed Primary CNS Lymphoma; CISL 10-01 Study
Not yet reported Samsung Medical Center 36 participants Est. completion 2012-05 1 siteOther conditions: CNS LymphomaView official trial listing → -
Terminated NCT NCT01083563
Draining PLN and Synovial Inflammation in RA Knee Joints Pre and Post Anti-TNF or B Cell Depletion Therapy
University of Rochester 7 participants Est. completion 2015-03 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01085617
Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia
University College, London Est. completion 2025-02-24 Stand-aloneOther conditions: Leukemia, Mucositis, Oral ComplicationsView official trial listing → -
Status unknown NCT NCT01087398
Hematopoietic Stem Cell Transplantation for Malignant Infantile Osteopetrosis
Not yet reported, Not yet reported Tehran University of Medical Sciences 10 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: OsteopetrosisView official trial listing → -
Completed NCT NCT01093885
Study of Ambrisentan With Antifibrotic Agent Combination Therapy in Diffuse Systemic Sclerosis
Not yet reported University of Pennsylvania 15 participants Est. completion 2016-07 1 siteOther conditions: Systemic Sclerosis, SclerodermaView official trial listing → -
Completed NCT NCT01104025
Hybrid Immunotherapy for Hemophagocytic LymphoHistiocytosis
Not yet reported Children's Hospital Medical Center, Cincinnati 31 participants Est. completion 2016-04 15 sites Stand-aloneOther conditions: Hemophagocytic LymphohistiocytosisView official trial listing → -
Completed NCT NCT01106079
TIght COntrol of Psoriatic Arthritis
Not yet reported Julia Brown 206 participants Est. completion 2013-01 3 sites Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Status unknown NCT NCT01108952
The Impact of Chemotherapy on Memory Function and the Development of Traumatic Symptoms in Children With Cancer
Tel-Aviv Sourasky Medical Center 45 participants Est. completion 2013-12 1 siteOther conditions: Oncology, Trauma, PediatricView official trial listing → -
Completed NCT NCT01116141
A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)
Not yet reported Chelsea Therapeutics 250 participants Est. completion 2012-05Other conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01117129
A Study of Efficacy of Rituximab [Mabthera/Rituxan] in Patients With Rheumatoid Arthritis Using Magnetic Resonance Imaging of the Hand (RESONAR)
Not yet reported Hoffmann-La Roche 2 participants Est. completion 2010-06 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01117441
International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia
Not yet reported University Hospital Schleswig-Holstein 6136 participants Est. completion 2021-12-31 139 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT01118013
Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Malignancies or Secondary Myelodysplasia Previously Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant
Not yet reported Alliance for Clinical Trials in Oncology 6 participants Est. completion 2013-08 10 sites Stand-aloneOther conditions: Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT01120366
Success of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After Discontinuation
Not yet reported SURPRISE Study Group 233 participants Est. completion 2014-12 30 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01123265
National Psoriasis Foundation - Dendritic Cell-Specific Transmembrane Protein (DC-Stamp) Biomarker Study
University of Rochester 22 participants Est. completion 2014-06 1 siteOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT01131910
TBE-vaccine to Patients With Rheumatoid Arthritis Who Are Using Immunosuppressive Drugs
Not yet reported Sormland County Council, Sweden 68 participants Est. completion 2011-05 6 sitesOther conditions: Rheumatoid Arthritis, Exposed to TBE-virus, ImmunosuppressionView official trial listing → -
Completed NCT NCT01142726
Efficacy and Safety Study of Abatacept Subcutaneous Plus Methotrexate in Inducing Remission in Adults With Very Early Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 511 participants Est. completion 2014-10 73 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01148173
High-dose Chemotherapy and Stem Cell Transplantation for Central Nervous System (CNS) Relapse of Aggressive Lymphomas
Not yet reported Charite University, Berlin, Germany 30 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Completed NCT NCT01156883
Combination Chemotherapy in Treating Young Adult Patients With Acute Lymphoblastic Leukemia
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 76 participants Est. completion 2017-10-31 43 sitesOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT01158885
Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 2 participants Est. completion 2012-10-24 2 sites Stand-aloneOther conditions: Minimal Residual Disease, Leukemia, Lymphoblastic, Acute, Leukemia, Myelogenous, AcuteView official trial listing → -
Completed NCT NCT01162421
A Canadian Study to Evaluate Early Use of Adalimumab After Methotrexate Failure in Early Rheumatoid Arthritis
Not yet reported AbbVie (prior sponsor, Abbott) 77 participants Est. completion 2015-07 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01162551
Trial of Sirolimus and Methotrexate in Relapsed/Refractory Lymphoblastic Leukemia and Lymphoma
Not yet reported Children's Hospital of Philadelphia 5 participants Est. completion 2017-02 1 site Stand-aloneOther conditions: Cancer, Leukemia, LymphomaView official trial listing → -
Completed NCT NCT01163747
A Study of the Effects of RoActemra/Actemra on Vaccination in Patients With Rheumatoid Arthritis on Background Methotrexate (VISARA)
Not yet reported Genentech, Inc. 91 participants Est. completion 2012-06 47 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01164579
Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)
Not yet reported Pfizer 109 participants Est. completion 2013-11 40 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01168219
Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia
Not yet reported National Cancer Institute (NCI) 68 participants Est. completion 2020-02-01 17 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Adult Acute Megakaryoblastic Leukemia, Adult Acute Monoblastic Leukemia, Adult Acute Monocytic Leukemia, Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11, Adult Acute Myeloid Leukemia With Maturation, Adult Acute Myeloid Leukemia With Minimal Differentiation, Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11, Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1, Adult Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3); MLLT3-MLL, Adult Acute Myeloid Leukemia Without Maturation, Adult Acute Myelomonocytic Leukemia, Adult Erythroleukemia, Adult Pure Erythroid Leukemia, Alkylating Agent-Related Acute Myeloid Leukemia, de Novo Myelodysplastic Syndrome, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts, Recurrent Adult Acute Myeloid Leukemia, Secondary Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01172639
Effectiveness in Daily Practice of Different Treatment Strategies for Early Rheumatoid Arthritis.
Not yet reported P. Verschueren 400 participants Est. completion 2015-06 17 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01175772
Maintenance Treatment for Ovarian Carcinoma in Remission by an Antiangiogenic Treatment Strategy
Not yet reported HaEmek Medical Center, Israel 6 participants Est. completion 2013-04 1 site Stand-aloneOther conditions: Ovarian CarcinomaView official trial listing → -
Completed NCT NCT01176981
Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With Osteosarcoma
Not yet reported The Hospital for Sick Children 6 participants Est. completion 2012-10 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT01177371
High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma
Not yet reported Case Comprehensive Cancer Center 13 participants Est. completion 2010-02 1 site Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With T(15;17)(q22;q12), Adult Acute Myeloid Leukemia With T(16;16)(p13;q22), Adult Acute Myeloid Leukemia With T(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Acute Promyelocytic Leukemia (M3), Adult Erythroleukemia (M6a), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Adult Pure Erythroid Leukemia (M6b), Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Burkitt Lymphoma, Childhood Acute Erythroleukemia (M6), Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloblastic Leukemia With Maturation (M2), Childhood Acute Myeloblastic Leukemia Without Maturation (M1), Childhood Acute Myeloid Leukemia in Remission, Childhood Acute Myelomonocytic Leukemia (M4), Childhood Acute Promyelocytic Leukemia (M3), Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Chronic Phase Chronic Myelogenous Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, De Novo Myelodysplastic Syndromes, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Peripheral T-Cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult Non-Hodgkin Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic Syndromes, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Testicular Lymphoma, Waldenstrom MacroglobulinemiaView official trial listing → -
Completed NCT NCT01180361
Atherosclerosis in Rheumatoid Arthritis and Lupus: Restoring Cholesterol Balance
NYU Langone Health 176 participants Est. completion 2025-06-20 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01181271
Tandem Auto-Allo Transplant for Lymphoma
Not yet reported Massachusetts General Hospital 42 participants Est. completion 2016-02 2 sites Stand-aloneOther conditions: Diffuse, Large B-Cell, Lymphoma, Lymphoma, Low-Grade, T-Cell Lymphoma, Mantle-Cell Lymphoma, Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Lymphoma, Small LymphocyticView official trial listing → -
Completed NCT NCT01184885
A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapy
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 7 participants Est. completion 2013-04 2 sites Stand-aloneOther conditions: Lymphoid Malignancies (New or Relapsed), Acute Lymphoblastic Leukemia, Burkitt Lymphoma, Lymphoblastic Lymphoma, Mantle Cell Lymphoma, Adult T-cell Leukemia/LymphomaView official trial listing → -
Completed NCT NCT01185288
A Study to Determine the Effect of Methotrexate (MTX) Dose on Clinical Outcome and Ultrasonographic Signs in Subjects With Moderately to Severely Active Rheumatoid Arthritis (RA) Treated With Adalimumab (MUSICA)
Not yet reported AbbVie (prior sponsor, Abbott) 309 participants Est. completion 2013-01 49 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01185301
Study to Determine the Effects of Different Doses of Methotrexate (MTX) When Taken With Adalimumab in Subjects With Early Rheumatoid Arthritis (RA)
Not yet reported AbbVie (prior sponsor, Abbott) 395 participants Est. completion 2012-09 68 sitesOther conditions: Early Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01185353
A Study in Participants With Rheumatoid Arthritis on Background Methotrexate Therapy
Not yet reported Eli Lilly and Company 301 participants Est. completion 2014-03 68 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Terminated NCT NCT01186328
EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL)
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 6 participants Est. completion 2012-01-10 7 sites Stand-aloneOther conditions: Lymphoblastic Leukemia, Acute, Lymphoblastic Leukemia, Acute, Childhood, Leukemia, Lymphoblastic, Acute, T Cell, Leukemia, Lymphoblastic, AcuteView official trial listing → -
Completed NCT NCT01187264
Dose Ranging Study to Compare the Efficacy and Safety of Methotrexate in Plaque Type Psoriasis
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 100 participants Est. completion 2009-09 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT01187563
A Study of Tocilizumab in Patients With Rheumatoid Arthritis
Regeneron Pharmaceuticals 16 participants Est. completion 2010-12 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01187810
Fenretinide in Children With Recurrent/Resistant ALL, AML, and NHL
Not yet reported South Plains Oncology Consortium 3 participants Est. completion 2018-04 2 sites Stand-aloneOther conditions: Acute Myelogenous Leukemia, Acute Lymphoblastic Leukemia, Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT01188798
Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies
Not yet reported St. Jude Children's Research Hospital 6 participants Est. completion 2012-02 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia, Chronic Myelocytic Leukemia, Hodgkin's Disease, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01190930
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma
Not yet reported Children's Oncology Group 9350 participants Est. completion 2026-03-31 243 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult B Lymphoblastic Lymphoma, Ann Arbor Stage I B Lymphoblastic Lymphoma, Ann Arbor Stage II B Lymphoblastic Lymphoma, Childhood B Acute Lymphoblastic Leukemia, Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Childhood B Lymphoblastic Lymphoma, Down Syndrome, Hypodiploid B Acute Lymphoblastic Leukemia, Philadelphia Chromosome PositiveView official trial listing → -
Completed NCT NCT01197066
Open-label, Extension Study of CDP870 in Patients With Rheumatoid Arthritis
Not yet reported Korea Otsuka Pharmaceutical Co., Ltd. 110 participants Est. completion 2016-11Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01197521
Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Not Responding.
Not yet reported AstraZeneca 923 participants Est. completion 2012-11 127 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01197755
Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate and Have Had Inadequate Response to Single TNF-alpha Antagonist
Not yet reported AstraZeneca 323 participants Est. completion 2013-02 135 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01198002
A Rheumatoid Arthritis Study in Participants on a Background Treatment of Methotrexate
Not yet reported Eli Lilly and Company 1041 participants Est. completion 2014-01 234 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT01204138
Concomitant Use of Apremilast for the Treatment of Active RA Despite TNF-Inhibition and Methotrexate- CATARA
Not yet reported Stanford University Est. completion 2011-12 1 siteOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT01204437
Adjuvant Chemotherapy for Elderly Non Frail Patients With an Increased Risk for Relapse of a Primary Carcinoma of the Breast
Not yet reported, Not yet reported GBG Forschungs GmbH 400 participants Est. completion 2014-01 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01208896
Allogeneic Hematopoietic Stem Cell Transplantation After Reduced-intensity Conditioning for Relapsed Follicular Lymphoma
Not yet reported University Hospital, Bordeaux 32 participants Est. completion 2017-09-28 26 sites Stand-aloneOther conditions: Lymphoma, Follicular, Stem Cell TransplantationView official trial listing → -
Completed NCT NCT01211249
GLPG0259 in Methotrexate-refractory Rheumatoid Arthritis
Not yet reported Lakefront Biotherapeutics NV 30 participants Est. completion 2011-04 32 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01211834
Efficacy and Safety of Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis
Not yet reported JW Pharmaceutical 90 participants Est. completion 2010-10 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01213017
The Effect of Certolizumab Pegol on MRI Synovitis and Bone Edema in Rheumatoid Arthritis Patients
Not yet reported Oklahoma Medical Research Foundation 20 participants Est. completion 2012-04 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01217814
Effect of SAR153191 (REGN88) With Methotrexate in Patients With Active Rheumatoid Arthritis Who Failed TNF-α Blockers
Not yet reported Sanofi 16 participants Est. completion 2011-09 14 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01224041
Study to Evaluate the Efficacy of Tacrolimus in Rheumatoid Arthritis Patients Shown Unsuccessful Response to Methotrexate
Not yet reported Astellas Pharma Inc 78 participants Est. completion 2011-06 5 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01224418
A Study to Evaluate the Efficacy of Tacrolimus in Rheumatoid Arthritis Patients Shown Unsuccessful Response to Methotrexate
Not yet reported Astellas Pharma Inc 50 participants Est. completion 2009-08 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01225393
A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis
Not yet reported Genentech, Inc. 211 participants 67 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01225874
Biomarkers to Classify Young Patients With Acute Lymphoblastic Leukemia (ALL) and Remission Induction Therapy in Young Patients With B-Precursor ALL
Not yet reported Children's Oncology Group 3762 participants Stand-aloneOther conditions: LeukemiaView official trial listing → -
Withdrawn NCT NCT01227408
Neoadjuvant Doxorubicin, Polyglutamate Paclitaxel, Capecitabine and Metronomic Chemotherapy in Breast Cancer
Not yet reported University of Southern California Est. completion 2011-02 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01228331
Clofarabine or High-Dose Cytarabine and Pegaspargase in Children with ALL
Not yet reported, Not yet reported Universitätsklinikum Hamburg-Eppendorf 745 participants Est. completion 2024-11-20 14 sitesOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT01230827
A Study of the Safety and Efficacy of CNTO 148 (Golimumab) in Children With Juvenile Idiopathic Arthritis (JIA) and Multiple Joint Involvement Who Have Poor Response to Methotrexate (GO KIDS)
Not yet reported Janssen Research & Development, LLC 173 participants Est. completion 2014-05 35 sites Stand-aloneOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT01230983
Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma
Not yet reported Children's Oncology Group 573 participants Est. completion 2004-10 Stand-aloneOther conditions: Cardiac Toxicity, Leukemia, LymphomaView official trial listing → -
Completed NCT NCT01232920
First-line Antimetabolites as Steroid-sparing Treatment Uveitis Pilot Trial
Not yet reported University of California, San Francisco 80 participants Est. completion 2012-06 2 sitesOther conditions: UveitisView official trial listing → -
Completed NCT NCT01235507
A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Disease-Modifying Antirheumatic Drugs (DMARDs) (ALABASTER)
Not yet reported Hoffmann-La Roche 71 participants Est. completion 2012-12 3 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01236118
A Study of LY2439821 in Rheumatoid Arthritis
Not yet reported Eli Lilly and Company 28 participants Est. completion 2013-01 6 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01238159
Concomitant Chemo-radiotherapy Followed by MIDLE Chemotherapy in Stage I/II Extranodal NK/T-cell Lymphoma
Not yet reported Samsung Medical Center 30 participants Est. completion 2014-12 1 siteOther conditions: Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-TypeView official trial listing → -
Status unknown NCT NCT01240850
Methotrexate as a Steroid-sparing Agent in Idiopathic Retroperitoneal Fibrosis: a Randomised, Multicenter Trial
Not yet reported University of Parma 200 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Idiopathic Retroperitoneal Fibrosis, Perianeurysmal Retroperitoneal Fibrosis, Chronic PeriaortitisView official trial listing → -
Completed NCT NCT01242488
Efficacy and Safety of CDP6038 in Patients With Rheumatoid Arthritis With an Unsuccessful Response to Anti-Tumor Necrosis Factor (Anti-TNF) Therapy
Not yet reported UCB Pharma 221 participants Est. completion 2012-06 82 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01242917
A Study to Evaluate the Safety and Efficacy of CCX354-C in Subjects With Rheumatoid Arthritis Partially Responsive to Methotrexate Therapy
Not yet reported Amgen 159 participants Est. completion 2011-07 41 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01245452
Study of the Response and Cardiorespiratory Endurance in Early RA Patients Treated With Tocilizumab or Methotrexate
Not yet reported Patrick Durez 30 participants Est. completion 2013-06 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01248780
Study of Subcutaneous Golimumab in Chinese Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Centocor, Inc. 264 participants Est. completion 2012-07 9 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01251120
A Study of RoActemra/Actemra (Tocilizumab) in Combination With DMARDs Versus Current Best Practice DMARD Therapy in Patients With Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 2 participants Est. completion 2013-01 6 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01251614
A Double Blind Study in Pediatric Subjects With Chronic Plaque Psoriasis, Studying Adalimumab vs. Methotrexate
Not yet reported AbbVie (prior sponsor, Abbott) 114 participants Est. completion 2015-02 Stand-aloneOther conditions: Plaque PsoriasisView official trial listing → -
Completed NCT NCT01253226
A Study for Japanese Participants With Rheumatoid Arthritis (RA)
Not yet reported Eli Lilly and Company 32 participants Est. completion 2011-08 10 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01253265
A Study in Rheumatoid Arthritis
Not yet reported Eli Lilly and Company 32 participants Est. completion 2011-12 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01253291
A Study of Japanese Rheumatoid Arthritis Participants
Not yet reported Eli Lilly and Company 26 participants Est. completion 2014-03 9 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01256398
Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 66 participants Est. completion 2021-11-15 101 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1View official trial listing → -
Terminated NCT NCT01258634
A Study of Pre-Operative Treatment of Newly-Diagnosed, Surgically-Resectable Osteosarcoma With Doxorubicin, Ifosfamide, Etoposide, and Cisplatin With Early Metabolic Assessment of Response
Not yet reported University of Chicago 2 participants Est. completion 2011-11 1 siteObstructive sleep apnea Other conditions: Lung MetastasesView official trial listing → -
Completed NCT NCT01258712
Study of Tocilizumab in Combination With Methotrexate for Treatment of Moderate to Severe Rheumatoid Arthritis Patients
Not yet reported Chugai Pharma Taiwan 86 participants Est. completion 2012-10 12 sites Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Status unknown NCT NCT01270035
Efficacy and Safety of Adalimumab 80 mg Every Other Week With Methotrexate
Not yet reported Keio University 40 participants 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01270997
Randomized Double-blind Parallel Trial to Evaluate Equivalence in Efficacy and Safety of HD203 and Enbrel in RA Patients
Not yet reported Hanwha Chemical 294 participants Est. completion 2012-05 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01281696
Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis
Not yet reported National Taiwan University Hospital 40 participants Est. completion 2013-10 1 site Stand-aloneOther conditions: Breast Neoplasms, Leptomeningeal Metastasis, Brain MetastasesView official trial listing → -
Completed NCT NCT01283399
An Observational Study of Rituximab in Combination With Methotrexate in Participants With Active Rheumatoid Arthritis
Hoffmann-La Roche 79 participants Est. completion 2014-04 5 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01283971
A Study of RoActemra/Actemra (Tocilizumab) Versus Adalimumab in Combination With Methotrexate (MTX) in Patients With Moderate to Severe Active Rheumatoid Arthritis And an Inadequate Response to Treatment With Only One Tumor Necrosis Factor (TNF)-Inhibitor
Not yet reported Hoffmann-La Roche 96 participants Est. completion 2012-08 170 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01285310
Study of Apremilast to Evaluate the Safety and Effectiveness for Patients With Rheumatoid Arthritis
Not yet reported Amgen 237 participants Est. completion 2012-09-10 50 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01285817
A Clinical Trial Using Metronomic Oral Low-dose Cyclophosphamide Alternating With Low-dose Oral Methotrexate With Continuous Celecoxib and Weekly Vinblastine in Children and Adolescents With Relapsed or Progressing soliD Tumours.
Not yet reported Assistance Publique Hopitaux De Marseille 79 participants Est. completion 2023-03-09 1 site Stand-aloneOther conditions: Survival Without ProgressionView official trial listing → -
Completed NCT NCT01290120
Chemotherapy Plus Rituximab Combination for Adult Lymphoblastic Leukemia (B-ALL) and Burkitt's Non-Hodgkin Lymphoma
Not yet reported Northern Italy Leukemia Group 182 participants Est. completion 2014-06 12 sitesOther conditions: Burkitt Lymphoma, B-ALLView official trial listing → -
Terminated NCT NCT01299545
Validation Study of RA-INF-Dx, a Multigene Molecular Test Used to Predict Non-Response to INfliximab Therapy
TcLand Expression S.A. 123 participants Est. completion 2012-10 37 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01303874
Etanercept and Methotrexate in Patients to Induce Remission in Early Arthritis (EMPIRE)
Not yet reported University of Leeds 112 participants Est. completion 2010-11-05 1 site Stand-aloneOther conditions: Rheumatoid Arthritis, Inflammatory ArthritisView official trial listing → -
Completed NCT NCT01305655
Glucarpidase Effect on Severe Delayed HDM-clearance in Children Treated With High-dose Mtx in ALL
Not yet reported Nordic Society for Pediatric Hematology and Oncology 47 participants Est. completion 2014-12 5 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL)View official trial listing → -
Completed NCT NCT01306474
Observation on the Treg in the Uveitis Patients
Xijing Hospital 30 participants Est. completion 2010-08 1 siteOther conditions: UveitisView official trial listing → -
Completed NCT NCT01308255
Infliximab as Induction Therapy in Early Rheumatoid Arthritis (IDEA)
Not yet reported University of Leeds 112 participants Est. completion 2011-02 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01312818
Bortezomib, Vorinostat and Dexamethasone for Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL)
Not yet reported Masonic Cancer Center, University of Minnesota 2 participants Est. completion 2013-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01313208
Moderate Rheumatoid Arthritis (RA) With Etanercept (Enbrel)
Not yet reported Amgen 210 participants Est. completion 2013-05 47 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01313858
A Study to Investigate the Use of Golimumab (Simponi®) in Participants With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis (P06554)
Merck Sharp & Dohme LLC 1613 participants Est. completion 2015-09Other conditions: Arthritis, Rheumatoid, Arthritis, Psoriatic, Spondylitis, AnkylosingView official trial listing → -
Terminated NCT NCT01314417
Treatment of Non-infectious Intermediate and Posterior Uveitis Associated Macular Edema With Intravitreal Methotrexate
Not yet reported, Not yet reported National Eye Institute (NEI) 2 participants Est. completion 2013-01 1 site Stand-aloneOther conditions: Non-infectious Intermediate and Posterior UveitisView official trial listing → -
Completed NCT NCT01317797
A Trial to Evaluate the Safety and Tolerability of Namilumab (MT203) in Patients With Mild to Moderate Rheumatoid Arthritis
Not yet reported Takeda 24 participants Est. completion 2013-08 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01319591
Comparison of Creatinine Clearance Calculation for Estimation of GFR in Patients Receiving HD Methotrexate
Dana-Farber Cancer Institute 40 participants Est. completion 2017-09-01 1 siteOther conditions: CNS Lymphoma, CNS Involvement of Systemic LymphomaView official trial listing → -
Completed NCT NCT01319981
Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2020-11-11 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT01323920
Bortezomib-based GVHD Prophylaxis After Allogeneic Transplant for Patients Without Matched Related Donors
Not yet reported Dana-Farber Cancer Institute 35 participants Est. completion 2013-11 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01324180
Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 14 participants Est. completion 2017-07-27 5 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01328522
Comparison of the Safety and Pharmacokinetics of Two SAR153191 (REGN88) Drug Products in Rheumatoid Arthritis Patients
Not yet reported Sanofi 32 participants Est. completion 2011-09 4 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01329991
Phase 1b Study of PLX5622 in Rheumatoid Arthritis Patients Who Are Receiving Methotrexate
Not yet reported Plexxikon 26 participants Est. completion 2011-10 4 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01338987
Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantation
Not yet reported National Cancer Institute (NCI) 76 participants Est. completion 2020-11-19 3 sites Stand-aloneOther conditions: Myelodysplastic Syndrome, Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia, Chronic Myelogenous Leukemia, Chronic Myelomonocytic LeukemiaView official trial listing → -
Completed NCT NCT01345682
LUX-Head&Neck 1: A Phase III Trial of Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic (R/M) Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy
Not yet reported Boehringer Ingelheim 483 participants Est. completion 2016-12-06 101 sitesOther conditions: Head and Neck Neoplasms, Carcinoma, Squamous CellView official trial listing → -
Completed NCT NCT01347983
Extension Study of Tocilizumab Long Term Treatment of Moderate to Severe Rheumatoid Arthritis Patients
Not yet reported Chugai Pharma Taiwan 72 participants Est. completion 2013-04 12 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01353859
A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Non-biologic DMARDs
Not yet reported Hoffmann-La Roche 39 participants Est. completion 2012-07 5 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01358201
PETHEMA LAL-07FRAIL: All Treatment In Fragile Patients Ph' Negative Over 55 Years
Not yet reported PETHEMA Foundation 100 participants Est. completion 2022-12 75 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01358253
Rituximab Plus Chemotherapy for CD20+ Adult Acute Lymphoblastic Leukemia
Not yet reported Ruijin Hospital 100 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01359150
A Study To Assess the Immune Response Following Administration Of Influenza and Pneumococcal Vaccines To Subjects With Rheumatoid Arthritis Receiving CP-690,550 Or Placebo
Not yet reported Pfizer 223 participants Est. completion 2012-02 57 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01359943
Efficacy, Safety and Tolerability of Secukinumab in Patients With Rheumatoid Arthritis Taking Methotrexate
Not yet reported Novartis Pharmaceuticals 221 participants Est. completion 2013-12 39 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01360970
Hepatitis A Vaccine in Patients With Immunomodulating Drugs
Not yet reported Lars Rombo 68 participants Est. completion 2011-05 4 sitesOther conditions: Response to Hepatitis A VaccineView official trial listing → -
Completed NCT NCT01362530
A Study of the Safety and Efficacy of Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting (CINV) in Pediatric Participants (MK-0869-208)
Not yet reported Merck Sharp & Dohme LLC 307 participants Est. completion 2013-08-16 Stand-aloneOther conditions: Chemotherapy Induced Nausea and VomitingView official trial listing → -
Completed NCT NCT01363128
Combination Chemotherapy and Ofatumumab in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Not yet reported M.D. Anderson Cancer Center 72 participants Est. completion 2020-04-08 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult Acute Lymphoblastic Leukemia in Complete Remission, Burkitt Leukemia, Burkitt Lymphoma, CD20 Positive, Childhood Acute Lymphoblastic Leukemia in Complete Remission, Lymphoblastic LymphomaView official trial listing → -
Status unknown NCT NCT01366898
Protocol For the Treatment Acute Lymphoblastic Leukemia With Ph 'Negative in Elderly Patients (> 55 Years)
Not yet reported PETHEMA Foundation 100 participants Est. completion 2022-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01373151
Phase IIB Rheumatoid Arthritis Dose Ranging Study for BMS-945429 in Subjects Who Are Not Responding to Methotrexate
Not yet reported CSL Behring 418 participants Est. completion 2015-06 100 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01376427
Treatment of Acute Lymphoblastic Leukemia Ph '(BCR / ABL) Positive Patients Aged > 55 Years
Not yet reported PETHEMA Foundation 100 participants Est. completion 2022-12 1 siteOther conditions: Acute Lymphoblastic Leukemia Ph PositiveView official trial listing → -
Completed NCT NCT01379209
Intravenous Administration of RGI-2001 in Patient Undergoing Allogenic Hematopoietic Stem Cell Transplantation (AHSCT)
Not yet reported, Not yet reported Regimmune Corporation 68 participants Est. completion 2017-04 6 sites Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT01382940
A Study on The Safety of Administering Rituximab at A More Rapid Rate in Patients With Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 351 participants Est. completion 2013-01-06 86 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01384461
An Observational Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (ACTIVATE)
Hoffmann-La Roche 251 participants Est. completion 2013-05 20 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01389076
Trial of Low-Dose Methotrexate and I 131 Tositumomab for Previously Untreated, Advanced-Stage, Follicular Lymphoma
Not yet reported University of Michigan Rogel Cancer Center 22 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Completed NCT NCT01390402
Alloreactive Haploidentical Natural Killer (NK) Cells With Busulfan and Fludarabine/ATG
Not yet reported M.D. Anderson Cancer Center 6 participants Est. completion 2014-11 1 site Stand-aloneOther conditions: Leukemia, Chronic Myelogenous LeukemiaView official trial listing → -
Terminated NCT NCT01390441
A Study of the Pharmacokinetics and Safety of MK-8808 (MK-8808-002)
Not yet reported Merck Sharp & Dohme LLC 100 participants Est. completion 2014-04 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01390545
VELVET, a Dose Range Finding Trial of Veltuzumab in Subjects With Moderate to Severe Rheumatoid Arthritis
Not yet reported Takeda 300 participants Est. completion 2012-10 63 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01393405
Methotrexate in Induction and Maintenance of Steroid Free Remission in Ulcerative Colitis
Not yet reported University of North Carolina, Chapel Hill 179 participants Est. completion 2017-04 31 sitesOther conditions: Ulcerative ColitisView official trial listing → -
Completed NCT NCT01393639
Study Comparing Doses Of An Experimental Glucocorticoid Compound To Prednisone And Placebo In Rheumatoid Arthritis
Not yet reported Pfizer 323 participants Est. completion 2014-06-09 93 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01399281
Pharmacovigilance in Juvenile Idiopathic Arthritis Patients Treated With Biologic Agents and/or Methotrexate
Istituto Giannina Gaslini 9000 participants Est. completion 2021-12 1 siteOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT01399372
Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphoma
Not yet reported Radiation Therapy Oncology Group 91 participants Est. completion 2022-05-20 45 sites Stand-aloneOther conditions: Chemotherapeutic Agent Toxicity, Cognitive/Functional Effects, Lymphoma, Neurotoxicity, Radiation ToxicityView official trial listing → -
Completed NCT NCT01399697
A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate Versus RoActemra/Actemra Monotherapy in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Not yet reported Hoffmann-La Roche 261 participants Est. completion 2014-05 54 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01403415
Temsirolimus, Dexamethasone, Mitoxantrone Hydrochloride, Vincristine Sulfate, and Pegaspargase in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma
Not yet reported National Cancer Institute (NCI) 13 participants 31 sites Stand-aloneOther conditions: Childhood B Acute Lymphoblastic Leukemia, Childhood T Acute Lymphoblastic Leukemia, Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT01404429
Study of Two Different Starting Doses of Methotrexate When Starting Treatment in Rheumatoid Arthritis
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 100 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01404585
Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 123 participants Est. completion 2013-02 29 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01407419
The CORRONA Treat to Target Trial: Outcomes and Feasibility in a US Population
Not yet reported CorEvitas 538 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01410695
Masitinib in Refractory Active Rheumatoid Arthritis
Not yet reported, Not yet reported AB Science 324 participants Est. completion 2015-10 1 site Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT01411267
AC220 for Children With Relapsed/Refractory ALL or AML
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 24 participants Est. completion 2013-09-12 11 sites Stand-aloneOther conditions: Lymphoblastic Leukemia, Acute, Childhood, Myelogenous Leukemia, Acute, ChildhoodView official trial listing → -
Completed NCT NCT01412879
S1106 Rituximab With Combination Chemotherapy or Bendamustine Hydrochloride Followed by Consolidation Chemotherapy and Stem Cell Transplantation in Older Patients With Previously Untreated Mantle Cell Lymphoma
Not yet reported SWOG Cancer Research Network 53 participants Est. completion 2021-03 204 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Status unknown NCT NCT01420432
Safety and Efficacy Study of Umbilical Cord/Placenta-Derived Mesenchymal Stem Cells to Treat Ankylosing Spondylitis (AS)
Not yet reported Shandong University 10 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Ankylosing SpondylitisView official trial listing → -
Active, not recruiting NCT NCT01424982
Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center 88 participants Est. completion 2027-10-31 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia, Adult Acute Lymphoblastic Leukemia in Complete Remission, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Philadelphia Chromosome Positive, Untreated Adult Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT01429610
Rituximab+mVPDL for CD20(+) Adult Acute Lymphoblastic Leukemia
Not yet reported Asan Medical Center 78 participants Est. completion 2019-01-01 19 sites Stand-aloneOther conditions: Precursor Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Completed NCT NCT01430507
A Clinical Trial to Study the Effects of Revamilast in Patients With Rheumatoid Arthritis
Not yet reported Glenmark Pharmaceuticals Ltd. India 406 participants Est. completion 2012-12 36 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01432145
A Clinical Trial in Patients With Breast Cancer Susceptibility Gene (BRCA) Defective Tumours
Not yet reported University of Oxford 74 participants Est. completion 2015-05 1 site Stand-aloneOther conditions: Breast Cancer, Ovarian CancerView official trial listing → -
Withdrawn NCT NCT01438021
Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease
Not yet reported City of Hope Medical Center Stand-aloneOther conditions: Leptomeningeal MetastasesView official trial listing → -
Completed NCT NCT01442545
A Study to Investigate How JNJ-39758979 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis Participants
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 21 participants Est. completion 2011-12 5 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01443364
Open Label Study to Assess the Predictability of Early Response to Certolizumab Pegol in Patients With Rheumatoid Arthritis
Not yet reported UCB Italy s.p.a. 132 participants Est. completion 2015-05 18 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01446211
Clinical Study Comparing the New Immunosuppressive Drug Gusperimus With the Conventional Treatment in Wegener's Granulomatosis
Not yet reported Nordic Pharma SAS 4 participants Est. completion 2015-01 1 siteOther conditions: Wegeners GranulomatosisView official trial listing → -
Status unknown NCT NCT01446978
Three Doses of Hepatitis A Vaccine in Patients With Immunomodulating Drugs
Not yet reported Sormland County Council, Sweden 150 participants Est. completion 2016-08 4 sitesOther conditions: Vaccine Response ImpairedView official trial listing → -
Status unknown NCT NCT01447381
Systemic Therapies for Pediatric Atopic Dermatitis
Rady Children's Hospital, San Diego 250 participants Est. completion 2021-07 3 sitesOther conditions: Dermatitis, AtopicView official trial listing → -
Completed NCT NCT01448096
Study in Patients With Primary Breast Diffuse Large B-cell Lymphoma
Not yet reported Chonbuk National University Hospital 33 participants Est. completion 2019-07-10 1 site Stand-aloneOther conditions: Large B Cell Diffuse LymphomaView official trial listing → -
Completed NCT NCT01450982
A Study to Investigate How JNJ-38518168 May Affect the Plasma Levels of Methotrexate in Rheumatoid Arthritis Participants
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 20 participants Est. completion 2011-10 4 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01451203
Efficacy Confirmation Study of CDP870 in Early Rheumatoid Arthritis
Not yet reported Astellas Pharma Inc 319 participants Est. completion 2014-10-20 8 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01451515
NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma
Not yet reported St. Jude Children's Research Hospital 23 participants Est. completion 2022-05-31 2 sites Stand-aloneOther conditions: Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT01451879
Observational Study for Subjects With Pompe Disease Undergoing Immune Modulation Therapies
University of Florida 11 participants Est. completion 2017-10 1 siteOther conditions: Pompe DiseaseView official trial listing → -
Completed NCT NCT01459484
ABCB1/P-glycoprotein Expression as Biologic Stratification Factor for Patients With Non Metastatic Osteosarcoma
Not yet reported Italian Sarcoma Group 225 participants Est. completion 2024-04-30 11 sites Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT01469013
Oral Baricitinib (LY3009104)Treatment in Japanese Participants With Active Rheumatoid Arthritis on Background Methotrexate Therapy
Not yet reported Eli Lilly and Company 145 participants Est. completion 2013-12 14 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT01471444
Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
Not yet reported M.D. Anderson Cancer Center 256 participants Est. completion 2020-12-14 1 site Stand-aloneOther conditions: Disorder Related to Bone Marrow Transplantation, Leukemia, Transplantation InfectionView official trial listing → -
Withdrawn NCT NCT01480388
A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate
Not yet reported Janssen Research & Development, LLC Est. completion 2014-03Other conditions: Active Rheumatoid Arthritis; Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01481272
Ofatumumab With IVAC Salvage Chemotherapy in Diffuse Large B Cell Lymphoma Patients
Not yet reported Polish Lymphoma Research Group 77 participants Est. completion 2018-12 8 sites Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Completed NCT NCT01481493
Dose-finding of Multiple Dose of BT061 in Patients With Active Rheumatoid Arthritis Incompletely Controlled on Stable Methotrexate (MTX)
Not yet reported Biotest 127 participants Est. completion 2013-11 39 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01483690
A Pilot Study of Decitabine and Vorinostat With Chemotherapy for Relapsed ALL
Not yet reported, Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 23 participants Est. completion 2015-07-31 28 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Precursor B-Cell Lymphoblastic Leukemia, Precursor T-Cell Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT01488253
Sirolimus/Tacrolimus Combination After HLA Matched Related Peripheral Blood Stem Cell Transplants
Not yet reported The Korean Society of Blood and Marrow Transplantation 3 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: Acute Leukemia in Remission, Myelodysplastic Syndromes, Leukemia, Myeloid, Chronic-Phase, Leukemia, Myeloid, Accelerated-PhaseView official trial listing → -
Completed NCT NCT01490723
Zevalin-Containing Nonmyeloablative Conditioning for Stem Cell Transplantation (SCT)
Not yet reported M.D. Anderson Cancer Center 20 participants Est. completion 2019-04-24 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Status unknown NCT NCT01491815
Active Conventional Therapy Compared to Three Different Biologic Treatments in Early Rheumatoid Arthritis With Subsequent Dose Reduction
Not yet reported Karolinska Institutet 812 participants Est. completion 2023-12 30 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01491958
Safety & Efficacy of Atorvastatin for Prophylaxis of Acute Graft Versus Host Disease in Patients With Hematological Malignancies HLA- Donor Hematopoietic Stem Cell Transplantation
Not yet reported Ohio State University Comprehensive Cancer Center 40 participants Est. completion 2016-06-27 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01499732
Exploratory Trial to Evaluate Premature Endothelial Dysfunction in Early Rheumatoid Arthritis(RA)Compared to Patients With Established RA, and Normal Subjects
Orrin M Troum, M.D. and Medical Associates 15 participants Est. completion 2012-11 1 siteOther conditions: Premature Endothelial Dysfunction, Rheumatoid Arthritis, HealthyView official trial listing → -
Completed NCT NCT01500278
Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate
Not yet reported UCB Pharma SA 915 participants Est. completion 2016-01 175 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01501149
Treatment of Natural Killer/T Cell Lymphoma-Ⅲ/Ⅳ
Not yet reported Mingzhi Zhang 80 participants Est. completion 2019-05 1 site Stand-aloneOther conditions: Nasal and Nasal-type NK/T-cell LymphomaView official trial listing → -
Completed NCT NCT01516580
Intergroup Randomized Trial for Children or Adolescents With B-Cell Non Hodgkin Lymphoma or B-Acute Leukemia: Rituximab Evaluation in High Risk Patients
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 482 participants Est. completion 2022-11-16 10 sites Stand-aloneOther conditions: B-cell Non Hodgkin Lymphoma, Mature B-cell Leukemia Burkitt-typeView official trial listing → -
Completed NCT NCT01516593
Short Term Intensified Chemo-immunotherapy in HIV-positive Patients With Burkitt Lymphoma
Not yet reported Andres J. M. Ferreri 19 participants Est. completion 2015-08 8 sites Stand-aloneOther conditions: HIV, Burkitt's LymphomaView official trial listing → -
Terminated NCT NCT01518153
Planned Donor Lymphocyte Infusion (DLI) After Allogeneic Stem Cell Transplantation (SCT)
Not yet reported M.D. Anderson Cancer Center 16 participants Est. completion 2014-08 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Myeloma, Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT01519791
A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis
Not yet reported UCB Pharma SA 880 participants Est. completion 2015-09 178 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01521923
A Multi-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Certolizumab Pegol in Combination With Methotrexate in the Treatment of Disease Modifying Antirheumatic Drugs (DMARD)-naïve Adults With Early Active Rheumatoid Arthritis
Not yet reported UCB Pharma 359 participants Est. completion 2015-09 178 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01526057
A Pharmacokinetic/Pharmacodynamic Study Comparing PF-05280586 To Rituximab In Subjects With Active Rheumatoid Arthritis With An Inadequate Response To TNF Inhibitors (REFLECTIONS B328-01)
Not yet reported Pfizer 220 participants Est. completion 2014-05-07 84 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01527149
Ofatumumab in Combination With Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine Sulfate, and Dexamethasone Alternating With Ofatumumab in Combination With Cytarabine and Methotrexate in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma
Not yet reported Roswell Park Cancer Institute 37 participants Est. completion 2024-01-11 2 sites Stand-aloneOther conditions: Stage I Mantle Cell Lymphoma, Stage II Contiguous Mantle Cell Lymphoma, Stage II Non-Contiguous Mantle Cell Lymphoma, Stage III Mantle Cell Lymphoma, Stage IV Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT01528163
Study Comparing Two Treatments in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 101 participants Est. completion 2014-11 16 sitesOther conditions: Squamous Cell Carcinoma of the Head and NeckView official trial listing → -
Completed NCT NCT01529827
Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
Not yet reported Roswell Park Cancer Institute 94 participants Est. completion 2019-08-29 1 site Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Aplastic Anemia, Burkitt Lymphoma, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Grade III Lymphomatoid Granulomatosis, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Congenital Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Hepatosplenic T-cell Lymphoma, Juvenile Myelomonocytic Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Paroxysmal Nocturnal Hemoglobinuria, Peripheral T-cell Lymphoma, Polycythemia Vera, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Primary Myelofibrosis, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Secondary Myelofibrosis, Severe Combined Immunodeficiency, Severe Congenital Neutropenia, Shwachman-Diamond Syndrome, Splenic Marginal Zone Lymphoma, T-cell Large Granular Lymphocyte Leukemia, Waldenstrom Macroglobulinemia, Wiskott-Aldrich SyndromeView official trial listing → -
Completed NCT NCT01535053
Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia
Not yet reported GOG Foundation 57 participants Est. completion 2020-07-17 289 sitesOther conditions: Choriocarcinoma, FIGO Stage I Gestational Trophoblastic Tumor, FIGO Stage II Gestational Trophoblastic Tumor, FIGO Stage III Gestational Trophoblastic Tumor, Hydatidiform MoleView official trial listing → -
Completed NCT NCT01540812
Treatment of Acute Lymphoblastic Leukemia HIGH RISK BCR / ABL NEGATIVE IN ADULTS
PETHEMA Foundation 418 participants Est. completion 2019-12-01 1 siteOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT01548001
Long-term Efficacy of Iguratimod Alone or Iguratimod in Combination With Methotrexate in Patients With Rheumatoid Arthritis
Not yet reported Jiangsu Simcere Pharmaceutical Co., Ltd. 910 participants Est. completion 2017-01 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01548768
RHYTHM (Formerly Escape II Myocardium)
Not yet reported Columbia University 149 participants Est. completion 2019-09 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01554696
A Study to Evaluate the Safety and Efficacy of ASP015K in Moderate to Severe Rheumatoid Arthritis Subjects Who Have Had an Inadequate Response to Methotrexate
Not yet reported Astellas Pharma Inc 379 participants Est. completion 2014-02-11 49 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT01557322
Characterize Patients With Moderately Active Rheumatoid Arthritis (RA)
Pfizer 1754 participants Est. completion 2012-09Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01558089
Good EULAR Response In Patients With Early Rheumatoid Arthritis
Pfizer 76 participants Est. completion 2015-05 9 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01565616
Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease
Not yet reported Emory University 22 participants Est. completion 2016-06-30 8 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT01567358
Study of NI-071 in Comparison With Remicade in Patients With Rheumatoid Arthritis
Not yet reported Nichi-Iko Pharmaceutical Co., Ltd. 14 participants Est. completion 2013-04 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01569074
Evaluation of Safety and Effectiveness of Fostamatinib Compared to Placebo in Patients in Asia With Rheumatoid Arthritis
Not yet reported AstraZeneca 163 participants Est. completion 2013-07 34 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01569152
Safety and Efficacy of MK-8457 and Methotrexate (MTX) in Participants With Active Rheumatoid Arthritis Despite MTX Therapy (P08683, MK-8457-008)
Not yet reported Merck Sharp & Dohme LLC 82 participants Est. completion 2013-10-03 Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT01571219
An Extension Study to Demonstrate Long-Term Efficacy and Safety of CT-P13 When Co-administered With Methotrexate in Patient With Rheumatoid Arthritis Who Were Treated With Infliximab (Remicade or CT-P13) in Study CT-P13 3.1
Not yet reported Celltrion 302 participants Est. completion 2013-07 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01572662
Allogeneic Transplantation Using Timed Sequential Busulfan and Fludarabine Conditioning
Not yet reported M.D. Anderson Cancer Center 201 participants Est. completion 2022-08-11 1 site Stand-aloneOther conditions: Leukemia, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia, Myeloproliferative Diseases, Non-Hodgkins Lymphoma, Hodgkins Lymphoma, Multiple Myeloma, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01578499
A Phase 3 Trial of Brentuximab Vedotin(SGN-35) Versus Physician's Choice (Methotrexate or Bexarotene) in Participants With CD30-Positive Cutaneous T-Cell Lymphoma (ALCANZA Study)
Not yet reported Millennium Pharmaceuticals, Inc. 131 participants Est. completion 2018-07-06 41 sitesOther conditions: Primary Cutaneous Anaplastic Large Cell Lymphoma, Mycosis Fungoides, Cutaneous T-Cell LymphomaView official trial listing → -
Completed NCT NCT01578850
Study Conducted in Subjects With Rheumatoid Arthritis Who Have Moderate to Severe Disease Activity Despite Methotrexate Therapy With or Without Other Non Biologic Disease Modifying Antirheumatic Drugs (DMARDs)for at Least 12 Weeks Prior to Screening
Not yet reported Pfizer 491 participants Est. completion 2015-03 62 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01583959
Study of Different Doses of Folic Acid in Combination With Methotrexate in Rheumatoid Arthritis
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 100 participants Est. completion 2013-12 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01587989
A Study of RoActemra/Actemra (Tocilizumab) With or Without Methotrexate in Patients With Mild to Moderate Rheumatoid Arthritis With an Inadequate Response to Methotrexate
Not yet reported Hoffmann-La Roche 77 participants Est. completion 2014-02 13 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01590459
24-week Study With Open Label Extension of VX-509, an Oral JAK3 Inhibitor, in Subjects Taking Methotrexate
Not yet reported Vertex Pharmaceuticals Incorporated 359 participants Est. completion 2014-07 94 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01593332
Low Dose Rituximab as a First Line Biologic Therapy for the Treatment of DMARD Resistant Patients With Rheumatoid Arthritis
Not yet reported Mashhad University of Medical Sciences 44 participants Est. completion 2011-10 1 siteOther conditions: DMARD Resistant Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01594333
Cardiovascular Inflammation Reduction Trial
Not yet reported Brigham and Women's Hospital 4786 participants Est. completion 2019-10-30 470 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT01596075
Safety and Efficacy of Cannabidiol for Grade I/II Acute Graft Versus Host Disease (GVHD) After Allogeneic Stem Cell Transplantation
Not yet reported, Not yet reported Rabin Medical Center 40 participants 1 site Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Withdrawn NCT NCT01598857
BIANCA-SC: A Study of the Efficacy, Safety, and Tolerability of Blisibimod in Addition to Methotrexate During Induction of Remission in Subjects With ANCA-Associated Small Vessel Vasculitis
Not yet reported Anthera PharmaceuticalsOther conditions: Granulomatosis With Polyangiitis, Microscopic PolyangiitisView official trial listing → -
Completed NCT NCT01600521
A Clinical Study of a Natural Remedy for Rheumatoid Arthritis vs. Commonly Used Conventional Medications
Not yet reported University of Minnesota 1748 participants Est. completion 2012-03 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01613001
Obesity as a Risk Factor for Musculoskeletal Diseases in the U.S. Air Force: Associations and Implications for Force Readiness
Mike O'Callaghan Military Hospital 67904 participants Est. completion 2013-11Other conditions: ObesityView official trial listing → -
Completed NCT NCT01613079
Efficacy and Safety of Tripterygium Wilfordii in Patients With Rheumatoid Arthritis
Not yet reported, Not yet reported Peking Union Medical College Hospital 201 participants Est. completion 2013-06 1 site Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT01613963
Causes of Visual Loss in Retinal Disease
Royal Surrey County Hospital NHS Foundation Trust 2000 participants Est. completion 2012-12 2 sitesOther conditions: Uveitis, ScleritisView official trial listing → -
Completed NCT NCT01614197
A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 16 participants Est. completion 2020-09-04 32 sites Stand-aloneOther conditions: Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Lymphoma, Peripheral T-cell LymphomaView official trial listing → -
Completed NCT NCT01617018
Assessing the Long Term Effectiveness and Safety of Biotherapies in the Treatment of Cutaneous Psoriasis
Assistance Publique - Hôpitaux de Paris 4613 participants Est. completion 2021-09-05 1 siteOther conditions: PsoriasisView official trial listing → -
Status unknown NCT NCT01617590
Disease-Modifying Antirheumatic Drugs Cycle Combination Therapy Research
Not yet reported Shanxi Medical University 500 participants Est. completion 2014-05 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01618955
Actual Human Use of Methotrexate (MTX) Subcutaneously Administered Via the VIBEX™ MTX Auto-Injector Device
Not yet reported Antares Pharma Inc. 101 participants Est. completion 2012-07 1 siteOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT01618968
Comparison of Methotrexate (MTX) and the VIBEX™ MTX Device
Not yet reported Antares Pharma Inc. 49 participants Est. completion 2012-08 1 site Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT01619176
Acupuncture Study on Rheumatoid Arthritis, Monitoring Microbiome and Blood
Not yet reported Chinese Academy of Sciences 10 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01629511
Allogeneic Stem Cell Transplant for CLL
Not yet reported, Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2018-04-25 1 site Stand-aloneOther conditions: Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia, Richter SyndromeView official trial listing → -
Status unknown NCT NCT01633983
Methotrexate for Central Serous Chorioretinopathy Treatment Trial
Not yet reported Edward Averbukh 20 participants Est. completion 2015-07 1 site Stand-aloneOther conditions: Central Serous ChorioretinopathyView official trial listing → -
Terminated NCT NCT01636843
A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Methotrexate
Not yet reported Novo Nordisk A/S 298 participants Est. completion 2014-11-10 139 sitesOther conditions: Inflammation, Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT01639521
Gemcitabine Hydrochloride and Cisplatin or High-Dose Methotrexate, Vinblastine, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Urothelial Cancer
Not yet reported University of Southern California Est. completion 2013-05 Stand-aloneOther conditions: Anterior Urethral Cancer, Localized Transitional Cell Cancer of the Renal Pelvis and Ureter, Posterior Urethral Cancer, Recurrent Bladder Cancer, Recurrent Urethral Cancer, Regional Transitional Cell Cancer of the Renal Pelvis and Ureter, Stage III Bladder Cancer, Transitional Cell Carcinoma of the Bladder, Ureter Cancer, Urethral Cancer Associated With Invasive Bladder CancerView official trial listing → -
Completed NCT NCT01645280
A Study of the Effectiveness and Safety of Ustekinumab (STELARA) and CNTO 1959 Administered Under the Skin of Patients With Active Rheumatoid Arthritis, Despite Existing Methotrexate Therapy
Not yet reported Janssen Research & Development, LLC 274 participants Est. completion 2014-05 47 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT01646385
Study to Assess the Safety and Efficacy of Etanercept in Patients Treated Over the Long-term in Real-world Clinical Practice, Using Data Collected by the British Society of Rheumatology Biologics Registry
Pfizer 6393 participants Est. completion 2012-08Other conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01651936
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Trial to Evaluate the Safety, Tolerability, and Efficacy of MK-8457 in Participants With Rheumatoid Arthritis (MK-8457-010)
Not yet reported Merck Sharp & Dohme LLC 56 participants Est. completion 2013-10-08 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01654575
Methotrexate in Symptomatic Knee Osteoarthritis
Not yet reported University of Alexandria 88 participants Est. completion 2012-01 1 site Stand-aloneOsteoarthritisView official trial listing → -
Terminated NCT NCT01659242
Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study
Not yet reported Singapore General Hospital 1 participants 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01661140
A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate in Patients With Severe Active Rheumatoid Arthritis, Comparing Tapering Versus Maintaining the Methotrexate Dosage
Not yet reported Hoffmann-La Roche 427 participants Est. completion 2015-02 67 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01661413
Nausea and Vomiting in Children Receiving Chemotherapeautic Monotherapy
The Hospital for Sick Children 88 participants Est. completion 2015-10-31 1 siteOther conditions: Acute LeukemiaView official trial listing → -
Completed NCT NCT01662167
Comparison of Single and Multiple-dose Methotrexate Therapy for Ectopic Pregnancy
Not yet reported Hormozgan University of Medical Sciences 87 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Pregnancy, EctopicView official trial listing → -
Terminated NCT NCT01663766
Phase I Study of Milatuzumab for Graft Versus Host Disease
Not yet reported Gilead Sciences 12 participants Est. completion 2015-03 1 site Stand-aloneOther conditions: GVHD (Acute or Chronic), Acute Myeloid or Lymphoblastic Leukemia (AML or ALL), Myelodysplastic Syndrome, Chronic Myelogenous Leukemia (CML), Multiple Myeloma (MM), Non-Hodgekin Lymphoma (NHL-both Follicular & Diffuse Large Cell), Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia (CLL or SLL)View official trial listing → -
Completed NCT NCT01664910
CMC-544 and Allogeneic Transplantation for CD22 Positive-Lymphoid Malignancies
Not yet reported, Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2023-06-28 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell NeoplasmView official trial listing → -
Status unknown NCT NCT01665001
Personalized Therapy of Precursor Lymphoid Neoplasms
Not yet reported Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice 200 participants Est. completion 2018-08 1 site Stand-aloneOther conditions: Precursor Lymphoid NeoplasmsView official trial listing → -
Completed NCT NCT01665677
Atorvastatin as GVHD Prophylaxis for Allogeneic Hematopoietic Cell Transplantation
Not yet reported Mehdi Hamadani 69 participants Est. completion 2021-07-09 2 sitesOther conditions: Graft vs Host DiseaseView official trial listing → -
Terminated NCT NCT01667289
Radiotherapy Alone Versus Concurrent Chemoradiation in Low Risk NK/T-cell Lymphoma
Not yet reported Fudan University 4 participants Est. completion 2017-06 1 site Stand-aloneOther conditions: Extranodal NK/T-cell Lymphoma, Nasal TypeView official trial listing → -
Completed NCT NCT01668641
Dose-ranging Study With GLPG0634 in Methotrexate-refractory Active Rheumatoid Arthritis Patients
Not yet reported Lakefront Biotherapeutics NV 91 participants Est. completion 2012-10 19 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01668680
Maintenance Metronomic Chemotherapy for Metastatic Colorectal Carcinoma
Not yet reported HaEmek Medical Center, Israel 80 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Colorectal Cancer MetastaticView official trial listing → -
Withdrawn NCT NCT01670084
Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia
Not yet reported Mayo Clinic Est. completion 2017-09 2 sites Stand-aloneOther conditions: B-cell Adult Acute Lymphoblastic Leukemia, Blastic Phase Chronic Myelogenous Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia, Untreated Adult Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT01676701
Evaluation of Tabalumab Using Auto-Injector or Prefilled Syringe in Participants With Rheumatoid Arthritis (RA)
Not yet reported Eli Lilly and Company 8 participants Est. completion 2013-08 37 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01679951
A Dose Range Finding Study of JNJ-38518168 in Patients With Active Rheumatoid Arthritis in Spite of Treatment With Methotrexate
Not yet reported Janssen Research & Development, LLC 272 participants Est. completion 2014-07-03 85 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01689532
A Study of CNTO 136 (Sirukumab) Administered Subcutaneously in Japanese Patients With Active Rheumatoid Arthritis Unresponsive to Methotrexate or Sulfasalazine
Not yet reported Janssen Pharmaceutical K.K. 122 participants Est. completion 2015-03 17 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT01700946
Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma
Not yet reported St. Jude Children's Research Hospital 80 participants Est. completion 2021-07-24 3 sitesOther conditions: Recurrent B-Cell Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood B-Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT01706926
A Study of Mavrilimumab in Subjects With Moderate-to-Severe Rheumatoid Arthritis
Not yet reported MedImmune LLC 420 participants Est. completion 2014-01 42 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01709578
To Evaluate The Effect Of SAR153191 (REGN88) Added To Other RA Drugs In Patients With RA Who Are Not Responding To Or Intolerant Of Anti-TNF Therapy (SARIL-RA-TARGET)
Not yet reported Sanofi 546 participants Est. completion 2015-03 196 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01709760
A Phase III Study to Evaluate the Efficacy and Safety of ENIA11 in Combination With Methotrexate Versus Methotrexate Alone in Patients With RA
Not yet reported Mycenax Biotech Inc. 91 participants Est. completion 2019-12 8 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01710358
A Study in Moderate to Severe Rheumatoid Arthritis
Not yet reported Eli Lilly and Company 1307 participants Est. completion 2015-09 213 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01711359
A Study in Participants With Moderate to Severe Rheumatoid Arthritis
Not yet reported Eli Lilly and Company 588 participants Est. completion 2015-08 154 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01715896
A Study of Mavrilimumab Versus Anti Tumor Necrosis Factor in Subjects With Rheumatoid Arthritis
Not yet reported MedImmune LLC 215 participants Est. completion 2015-02 39 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01716039
Pharmacokinetics of Adalimumab With Methotrexate for Treatment of Patients With Ulcerative Colitis (UC)
Not yet reported Alimentiv Inc. 22 participants Est. completion 2016-07-18Other conditions: Ulcerative ColitisView official trial listing → -
Status unknown NCT NCT01724268
Corticosteroids and Anti TNF in Methotrexate Inadequate Responder Rheumatoid Arthritis Patient
Not yet reported Hamad Medical Corporation 80 participants Est. completion 2014-09 1 site Stand-aloneOther conditions: RHEUMATOID ARTHRITISView official trial listing → -
Completed NCT NCT01724931
Aminopterin Dose Finding Treatment for Methotrexate-Naïve Rheumatoid Arthritis
Not yet reported Syntrix Biosystems, Inc. 175 participants Est. completion 2015-02 15 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01726959
Prediction of Methotrexate Response - A Pilot Study
Wake Forest University Health Sciences 36 participants Est. completion 2014-12 1 siteOther conditions: Rheumatoid Arthritis, Rheumatic DiseasesView official trial listing → -
Completed NCT NCT01736189
Assessment of Clinical Effectiveness and Safety of Adalimumab and High Dose Methotrexate in Routine Clinical Practice
AbbVie (prior sponsor, Abbott) 346 participants Est. completion 2018-04-16Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01737671
Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study
Not yet reported M.D. Anderson Cancer Center 7 participants Est. completion 2018-01-11 2 sites Stand-aloneOther conditions: Brain Tumor, Malignant Neoplasm of Fourth Ventricle of BrainView official trial listing → -
Completed NCT NCT01737944
Exposure Study Comparing 3 Routes of Methotrexate (MTX) Administration
Not yet reported, Not yet reported Antares Pharma Inc. 38 participants Est. completion 2011-06 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01741493
A Study in Healthy Adults and Adult Subjects With Rheumatoid Arthritis to Evaluate the Safety, Tolerability and Pharmacokinetics After Multiple Doses of ABT-494
Not yet reported AbbVie (prior sponsor, Abbott) 67 participants Est. completion 2013-12 5 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01741558
The Effects of mETHotrexate Therapy on ST Segment Elevation MYocardial InfarctionS (TETHYS Trial)
Not yet reported Instituto de Cardiologia do Rio Grande do Sul 80 participants Est. completion 2014-12 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01743131
Abatacept as GVHD Prophylaxis Phase 2
Not yet reported Boston Children's Hospital 186 participants Est. completion 2024-03-30 14 sites Stand-aloneOther conditions: Graft vs Host Disease, MalignancyView official trial listing → -
Completed NCT NCT01745055
Co-Administration Of Methotrexate And CP-690,550
Not yet reported Pfizer 12 participants Est. completion 2006-06 4 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01746680
Efficacy and Safety Study of Tacrobell to Treat Rheumatoid Arthritis
Not yet reported Chong Kun Dang Pharmaceutical 111 participants Est. completion 2015-06 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01746992
CTOP/ITE/MTX Compared With CHOP as the First-line Therapy for Newly Diagnosed Young Patients With T Cell Lymphoma
Not yet reported Ruijin Hospital 200 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: ALK-negative Anaplastic Large Cell Lymphoma, Peripherial T Cell Lymphoma,Not Otherwise Specified, Angioimmunoblastic T Cell Lymphoma, Enteropathy Associated T Cell Lymphoma, Hepatosplenic T Cell Lymphoma, Subcutaneous Panniculitis Like T Cell LymphomaView official trial listing → -
Terminated NCT NCT01749111
Comparison Between Cyclophosphamide and Combination of Methotrexate + Calcineurin Inhibitor for GVHD Prophylaxis
Not yet reported Hospital Israelita Albert Einstein 3 participants Est. completion 2016-08 1 siteOther conditions: Acute Myelogenous Leukemia, Acute Lymphoid Leukemia, Myeloproliferative Disease, Myelodysplastic Syndrome, Chronic Myeloid Leukemia, Chronic Myelomonocytic LeukemiaView official trial listing → -
Completed NCT NCT01749787
Safety Study of PRTX-100 With Methotrexate or Leflunomide to Treat Active Rheumatoid Arthritis
Not yet reported Protalex, Inc. 61 participants Est. completion 2014-08 8 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT01751776
Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effects of Multiple Rising Subcutaneous Doses of BI 655064 in Healthy Volunteers and in Rheumatoid Arthritis Patients With Prior Inadequate Response to Methotrexate Therapy
Not yet reported Boehringer Ingelheim 107 participants Est. completion 2015-04-27 25 sitesOther conditions: Arthritis, Rheumatoid, HealthyView official trial listing → -
Completed NCT NCT01751997
Family-mismatched/Haploidentical Donors Versus Matched Unrelated Donors
Not yet reported, Not yet reported Byung-Sik Cho 116 participants Est. completion 2019-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01754389
Standard of Care vs. Bortezomib in Graft-Versus Host Disease After Hematopoietic Stem Cell Transplant
Not yet reported Dana-Farber Cancer Institute 138 participants Est. completion 2016-11 4 sites Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT01754805
A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Methotrexate in Patients With Rheumatoid Arthritis
Not yet reported Astellas Pharma Inc 15 participants Est. completion 2010-03-25 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01758198
Abatacept Post-marketing Clinical Study in Japan
Not yet reported Bristol-Myers Squibb 405 participants Est. completion 2016-12-26 74 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01758666
A Clinical Research on the Relation of Blood Drug Concentration and Calcium Folinate Rescued in High-dose MTX Therapy
Not yet reported Tianjin Medical University Cancer Institute and Hospital 40 participants Est. completion 2016-12 Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT01759030
Study of Safety and Efficacy of BCD-020 Comparing to MabThera in Patients With Rheumatoid Arthritis
Not yet reported Biocad 181 participants Est. completion 2015-07 40 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01760226
Dose Adjusted EPOCH-R, to Treat Mature B Cell Malignancies
Not yet reported Baylor College of Medicine 4 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Diffuse Large B Cell Lymphoma, Post Transplant Lymphoproliferative Disorder, Primary Mediastinal (Thymic) Large B-cell LymphomaView official trial listing → -
Completed NCT NCT01761019
A Study to Determine the Efficacy of Taclonex Topical Suspension as a Supplement to Non-biologic Systemic Therapy
Not yet reported University of Pittsburgh 8 participants Est. completion 2014-09 1 siteOther conditions: PsoriasisView official trial listing → -
Terminated NCT NCT01764997
An Evaluation of Sarilumab Plus Methotrexate Compared to Etanercept Plus Methotrexate in RA Patients Not Responding to Adalimumab Plus Methotrexate
Not yet reported Sanofi 776 participants Est. completion 2015-01 257 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01766375
the Effects and Safety of Idarubicin-strengthened Pretreatment Program and Conventional Busulfan Cyclophosphamide Pretreatment Program on High-risk Acute Myeloid Leukemia Patient
Not yet reported Guangxi Medical University 200 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01768572
To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)
Not yet reported Sanofi 202 participants Est. completion 2014-10 78 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01769209
Bortezomib and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported Stanford University 18 participants Est. completion 2017-07-04 1 site Stand-aloneOther conditions: B-cell Adult Acute Lymphoblastic Leukemia (ALL), Ph-positive Adult Acute Lymphoblastic Leukemia (ALL), Recurrent Adult Acute Lymphoblastic Leukemia (ALL), T-cell Adult Acute Lymphoblastic Leukemia (ALL)View official trial listing → -
Terminated NCT NCT01773395
GVAX vs. Placebo for MDS/AML After Allo HSCT
Not yet reported Dana-Farber Cancer Institute 123 participants Est. completion 2021-11-24 4 sitesOther conditions: Myelodysplastic Syndrome, Acute Myeloid Leukemia, Chronic Myelomonocytic LeukemiaView official trial listing → -
Completed NCT NCT01782339
A Novel Single Arm Phase II Study for Relapsed Germ Cell Tumours With Poor Prognosis
Not yet reported Barts & The London NHS Trust 45 participants Est. completion 2021-05-05 1 site Stand-aloneOther conditions: Germ Cell TumourView official trial listing → -
Terminated NCT NCT01783015
Study of Etanercept in Subjects With Rheumatoid Arthritis Who Have Had an Inadequate Response to Adalimumab or Infliximab Plus Methotrexate
Not yet reported Pfizer 16 participants Est. completion 2014-08 15 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01785810
Phase II Maraviroc for GVHD Prevention
Not yet reported Abramson Cancer Center at Penn Medicine 37 participants Est. completion 2018-07-12 1 site Stand-aloneOther conditions: Hematologic MalignancyView official trial listing → -
Status unknown NCT NCT01786018
Thiotepa, Busulfan and Fludarabin for pt With Refractory/Early Relapsed Aggressive B-cell Non Hodgkin Lymphomas
Not yet reported Azienda Ospedaliera San Giovanni Battista 42 participants Est. completion 2015-02 1 site Stand-aloneOther conditions: B-cell Lymphoma RefractoryView official trial listing → -
Completed NCT NCT01788189
Lenalidomide, MTX, Ara-C and Rituximab in Relapsed Aggressive B-cell Lymphomas
Not yet reported, Not yet reported University Hospital, Essen 37 participants Est. completion 2020-02-20 1 site Stand-aloneOther conditions: B-cell LymphomaView official trial listing → -
Completed NCT NCT01788501
Tacrolimus/Methotrexate Versus Cyclosporine/Methotrexate for Prophylaxis of Graft Versus Host Disease
Not yet reported, Not yet reported Seoul National University Hospital 50 participants Est. completion 2017-03-01 3 sites Stand-aloneOther conditions: Graft vs Host DiseaseView official trial listing → -
Completed NCT NCT01789255
Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies
Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2014-03 1 site Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Grade III Lymphomatoid Granulomatosis, B-cell Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Contiguous Stage II Adult Burkitt Lymphoma, Contiguous Stage II Adult Diffuse Large Cell Lymphoma, Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Contiguous Stage II Adult Lymphoblastic Lymphoma, Contiguous Stage II Grade 1 Follicular Lymphoma, Contiguous Stage II Grade 2 Follicular Lymphoma, Contiguous Stage II Grade 3 Follicular Lymphoma, Contiguous Stage II Mantle Cell Lymphoma, Contiguous Stage II Marginal Zone Lymphoma, Contiguous Stage II Small Lymphocytic Lymphoma, Cutaneous B-cell Non-Hodgkin Lymphoma, Graft Versus Host Disease, Intraocular Lymphoma, Myelodysplastic Syndrome With Isolated Del(5q), Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Burkitt Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Grade 1 Follicular Lymphoma, Noncontiguous Stage II Grade 2 Follicular Lymphoma, Noncontiguous Stage II Grade 3 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Noncontiguous Stage II Marginal Zone Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Post-transplant Lymphoproliferative Disorder, Primary Central Nervous System Hodgkin Lymphoma, Primary Central Nervous System Non-Hodgkin Lymphoma, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory Anemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Ringed Sideroblasts, Refractory Chronic Lymphocytic Leukemia, Refractory Cytopenia With Multilineage Dysplasia, Refractory Hairy Cell Leukemia, Relapsing Chronic Myelogenous Leukemia, Secondary Central Nervous System Hodgkin Lymphoma, Secondary Central Nervous System Non-Hodgkin Lymphoma, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Diffuse Small Cleaved Cell Lymphoma, Stage I Adult Hodgkin Lymphoma, Stage I Adult Immunoblastic Large Cell Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Small Lymphocytic Lymphoma, Stage II Adult Hodgkin Lymphoma, Stage II Chronic Lymphocytic Leukemia, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Hodgkin Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Hodgkin Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Small Lymphocytic Lymphoma, Testicular Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT01790568
Vorinostat Plus Tacrolimus & Methotrexate to Prevent Graft vs Host Disease Following Unrelated Stem Cell Transplant
Not yet reported University of Michigan Rogel Cancer Center 26 participants Est. completion 2017-10-31 1 site Stand-aloneOther conditions: Graft vs Host Disease, Hematologic Neoplasms, Non-Neoplastic Hematologic and Lymphocytic DisorderView official trial listing → -
Completed NCT NCT01791153
An Efficacy and Safety Study of Tocilizumab (RoActemra/Actemra) in Participants With Giant Cell Arteritis (GCA)
Not yet reported Hoffmann-La Roche 251 participants Est. completion 2018-06-04 78 sites Stand-aloneOther conditions: Giant Cell ArteritisView official trial listing → -
Completed NCT NCT01793259
Preference Methotrexate (MTX) Pre-filled Syringe Versus Pre-filled Pen in Rheumatoid Arthritis (RA)
Not yet reported medac GmbH 120 participants Est. completion 2013-06 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01800162
RCT for Women With a Persisting Pregnancy of Unknown Location
Not yet reported, Not yet reported University of Pennsylvania 2 participants Est. completion 2013-12 2 sitesOther conditions: Persistent Pregnancy of Unknown Location, Ectopic PregnancyView official trial listing → -
Terminated NCT NCT01802593
Comparison of 2 Immunomodulator Withdrawal Schemes for Infliximab Monotherapy in Active Pediatric Crohn's Disease After Thiopurine Failure
Not yet reported Prof. Arie Levine 20 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: Crohn's DiseaseView official trial listing → -
Status unknown NCT NCT01810926
T&B Depletion Non Malignant
Not yet reported Franco Locatelli 130 participants Est. completion 2016-10 4 sites Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT01812369
Perioperative Chemotherapy for Patients With Locally Advanced Bladder Cancer
Not yet reported University Hospital, Rouen 500 participants Est. completion 2023-09-25 1 siteOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT01812954
Economic Evaluation of Systemic Treatments for Moderate-to-severe Psoriasis
Jochen Schmitt. 1 participants Est. completion 2014-06Other conditions: PsoriasisView official trial listing → -
Completed NCT NCT01813617
Outcome in Patients With Recent Onset Polymyositis and Dermatomyositis
Karolinska University Hospital 72 participants 1 siteOther conditions: Polymyositis, DermatomyositisView official trial listing → -
Status unknown NCT NCT01823315
Methotrexate Single-dose Treatment and Methotrexate/Actinomycin-D Single-dose Treatment in Low-Risk Gestational Trophoblastic Neoplasia
Not yet reported Ding Ma 300 participants Est. completion 2019-12 3 sites Stand-aloneOther conditions: Gestational Trophoblastic Disease, Gestational Trophoblastic Neoplasia, Gestational Trophoblastic Tumor, Gestational Trophoblastic NeoplasmsView official trial listing → -
Completed NCT NCT01829295
Methotrexate and Mycophenolate Mofetil for UVEITIS
Not yet reported University of California, San Francisco 216 participants Est. completion 2018-08-09 9 sites Stand-aloneOther conditions: UveitisView official trial listing → -
Completed NCT NCT01830010
A Two-part Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of KRP203 in Patients Undergoing Stem Cell Transplant for Hematological Malignancies
Not yet reported Novartis Pharmaceuticals 23 participants Est. completion 2018-08-21 8 sites Stand-aloneOther conditions: Hematological MalignanciesView official trial listing → -
Status unknown NCT NCT01834157
Improvement of Hand Dysfunction by Arthritis in Systemic Sclerosis
Prof. Laszlo Czirjak 160 participants Est. completion 2017-11 33 sitesOther conditions: Systemic Sclerosis, ArthritisView official trial listing → -
Completed NCT NCT01835470
Efficacy, Safety, Pharmacokinetics and Immunogenicity Study of Abatacept Administered Intravenously to Treat Active Polyarticular-course Juvenile Idiopathic Arthritis in Japan
Not yet reported Bristol-Myers Squibb 23 participants Est. completion 2018-07-30 13 sitesOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT01844895
Methotrexate-Inadequate Response Autoinjector Device Sub Study
Not yet reported Bristol-Myers Squibb 120 participants Est. completion 2014-07Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01848457
Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy
Not yet reported Children's Hospital of Philadelphia 13 participants Est. completion 2016-10-01 1 site Stand-aloneObstructive sleep apnea Other conditions: Nephrotoxicity, OtotoxicityView official trial listing → -
Terminated NCT NCT01848652
Phase II Study Evaluating a Combination of Pegylated Liposomal Doxorubicin and Dexamethasone for the Treatment of Immunocompetent Patients With Cerebral Lymphoma Relapsed or Refractory to First-line Chemotherapy With High Dose Methotrexate (MTXHD) and / or High-dose Cytarabine.
Not yet reported University Hospital, Brest 5 participants Est. completion 2015-05 3 sitesOther conditions: Cerebral Lymphoma B Cell RefractoryView official trial listing → -
Completed NCT NCT01850121
Remicade in the Treatment of Patients With Active Ankylosing Spondylitis
Göteborg University 19 participants Est. completion 2008-05 1 siteOther conditions: Ankylosing SpondylitisView official trial listing → -
Completed NCT NCT01850680
Single Ascending Dose Study of Safety and Tolerability of Sarilumab and Methotrexate in Japanese Patients With Rheumatoid Arthritis
Not yet reported Sanofi 61 participants Est. completion 2013-12 2 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01851707
A Double-Blind Study Evaluating Duvelisib in Subjects With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to Methotrexate Alone
Not yet reported SecuraBio 322 participants Est. completion 2015-02 64 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT01854372
Rituximab-HyperCVAD (R-HCVAD) Alternating With Rituximab-Methotrexate-Cytarabine- (R-MC) in Newly Diagnosed Patients With Diffuse Large B-Cell Lymphoma With MYC-Rearrangement.
Not yet reported The University of Texas Health Science Center at San Antonio Est. completion 2013-11 Stand-aloneOther conditions: Newly Diagnosed Diffuse Large B-Cell Lymphoma, Intermediate (Burkitt-Like) LymphomaView official trial listing → -
Completed NCT NCT01855568
Methotrexate Treatment for Ectopic Pregnancy
Not yet reported CHA University 92 participants Est. completion 2015-04 1 site Stand-aloneOther conditions: Ectopic PregnancyView official trial listing → -
Completed NCT NCT01855789
A Study of the Impact of Methotrexate (MTX) Discontinuation on the Efficacy of Subcutaneous (SC) Tocilizumab (TCZ) With MTX
Not yet reported Hoffmann-La Roche 718 participants Est. completion 2016-10-14 155 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01856478
LUX-Head&Neck 3: Afatinib (BIBW2992) Versus Methotrexate for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer After Platinum Based Chemotherapy
Not yet reported Boehringer Ingelheim 340 participants Est. completion 2024-10-02 53 sitesOther conditions: Head and Neck NeoplasmsView official trial listing → -
Status unknown NCT NCT01858259
Treatment and Prevention of Progression of Interstitial Lung Disease in Systemic Sclerosis
Gabriela Riemekasten 1372 participants Est. completion 2016-06 11 sitesOther conditions: Systemic Sclerosis, Interstitial Lung DiseasesView official trial listing → -
Completed NCT NCT01858740
Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children
Not yet reported Fred Hutchinson Cancer Center 20 participants Est. completion 2023-07-30 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Leukemia of Ambiguous Lineage, Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Myelodysplastic Syndrome With Excess Blasts-1, Myelodysplastic Syndrome With Excess Blasts-2, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Refractory Adult Acute Lymphoblastic Leukemia, Refractory Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01859819
Treatment for Advanced B-Cell Lymphoma
Not yet reported New York Medical College 45 participants Est. completion 2021-06 5 sites Stand-aloneOther conditions: Diffuse Large Cell Lymphoma, Burkitt's Lymphoma, High Grade B-cell LymphomaView official trial listing → -
Status unknown NCT NCT01860690
BHCG Level in Day 4,7, in Comparison to Day 10 as an Indicator for Treatment Success
Not yet reported Meir Medical Center 100 participants Est. completion 2014-02 1 site Stand-aloneOther conditions: Ectopic PregnancyView official trial listing → -
Completed NCT NCT01860963
Anal Dysplasia in Patients With Inflammatory Bowel Disease and Healthy Controls
Not yet reported Stanford University 310 participants Est. completion 2013-06 1 siteOther conditions: Anal Squamous Intraepithelial Lesion (ASIL), HPV DNAView official trial listing → -
Completed NCT NCT01861002
A Phase I Study of 5-Azacytidine in Combination With Chemotherapy for Children With Relapsed or Refractory ALL or AML
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 15 participants Est. completion 2014-07-28 23 sites Stand-aloneOther conditions: Lymphoblastic Leukemia, Acute, Childhood, Myelogenous Leukemia, Acute, ChildhoodView official trial listing → -
Terminated NCT NCT01862224
A Synovial Biopsy Study of JNJ-38518168 in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Janssen Research & Development, LLC 21 participants Est. completion 2014-07 2 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01866150
A Retrospective, Observational Chart Review of Biologics in Monotherapy Versus the Combination Biologic Plus Methotrexate in Patients With Rheumatoid Arthritis
Hoffmann-La Roche 476 participants Est. completion 2014-03 15 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01870128
Comparison of Three Different Treatment Regimes in Early Rheumatoid Arthritis: A Randomized Open-labelled Trial
Not yet reported All India Institute of Medical Sciences 60 participants Est. completion 2011-06 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01871649
Initial Treatment With Golimumab in Early PsA
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 51 participants Est. completion 2018-11 2 sites Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT01871961
Evaluation of Patient Performance Using the Metoject Device for Subcutaneous Injection in Rheumatoid Arthritis (RA)Patient
Not yet reported medac GmbH 105 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Terminated NCT NCT01875237
Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene
Not yet reported, Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2017-03-07 1 site Stand-aloneOther conditions: Leukemia, Myeloma, Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT01876004
Effectiveness Of Expectant Management In The Tubal Ectopic Pregnancy
Not yet reported Federal University of São Paulo 25 participants Est. completion 2013-06 1 site Stand-aloneOther conditions: Ectopic PregnancyView official trial listing → -
Completed NCT NCT01876082
PAZOPANIB Efficacy and Tolerance in Desmoids Tumors
Not yet reported Institut Bergonié 72 participants Est. completion 2019-09 1 siteOther conditions: Progressive Desmoids TumorsView official trial listing → -
Withdrawn NCT NCT01878318
A Study of The Effect of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate on Articular Damage in The Hand in Patients With Moderate to Severe Rheumatoid Arthritis Who Have an Inadequate Response to Non-Biological DMARDs
Not yet reported Hoffmann-La Roche Est. completion 2015-06 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01883180
ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis
Not yet reported Nanfang Hospital, Southern Medical University 412 participants Est. completion 2018-01 1 site Stand-aloneOther conditions: Hematopoietic Stem Cell Transplantation, Antithymocyte Globulin, Viral InfectionView official trial listing → -
Completed NCT NCT01884623
Phase III Trial Comparing Methotrexate and Cetuximab in First-line Treatment of Recurrent and/or Metastatic Squamous Cell Head and Neck Cancer
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 82 participants Est. completion 2021-10-12 1 siteOther conditions: Head Neck Cancer Squamous Cell RecurrentView official trial listing → -
Completed NCT NCT01884636
A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Methotrexate
Not yet reported Astellas Pharma Global Development, Inc. 24 participants Est. completion 2013-03 1 site Stand-aloneOther conditions: Pharmacokinetics of Isavuconazole, Pharmacokinetics of Methotrexate, Pharmacokinetics of 7-hydroxymethotrexate, Healthy SubjectsView official trial listing → -
Completed NCT NCT01886651
The Influence of Thiopurine Methyltransferase Activity on Toxicity After High-dose Methotrexate in Childhood Acute Lymphoblastic Leukemia
Copenhagen University Hospital, Rigshospitalet 411 participants Est. completion 2012-02 1 siteOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT01887587
Vincristine, Doxorubicin, And Dexamethasone + Ixazomib in Acute Lymphoblastic Leukemia (ALL), Lymphoblastic Lymphoma Or Mixed Phenotype Acute Leukemia
Not yet reported Ehab L Atallah 5 participants Est. completion 2016-02-29 1 site Stand-aloneOther conditions: Relapsed or Refractory Acute Lymphoblastic Leukemia, Relapsed or Refractory Lymphoblastic Lymphoma, Mixed Phenotype Acute LeukemiaView official trial listing → -
Completed NCT NCT01888874
Dose-finding Study of GLPG0634 as add-on to Methotrexate in Active Rheumatoid Arthritis Participants (DARWIN1)
Not yet reported Lakefront Biotherapeutics NV 599 participants Est. completion 2015-05-14 142 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01894516
Dose-finding Study of GLPG0634 as Monotherapy in Active Rheumatoid Arthritis (RA) Participants (DARWIN2)
Not yet reported Lakefront Biotherapeutics NV 287 participants Est. completion 2015-05-29 82 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01895309
A Study Comparing SB4 to Enbrel® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Samsung Bioepis Co., Ltd. 596 participants Est. completion 2015-10 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01895764
Effect of the Combination of Methotrexate and Adalimumab on Reduction of Immunization in Ankylosing Spondylitis (COMARIS)
Not yet reported University Hospital, Tours 110 participants Est. completion 2015-04-27 11 sites Stand-aloneOther conditions: Ankylosing SpondylitisView official trial listing → -
Completed NCT NCT01896752
Renal and Hepatic Clearance Following High-Dose Methotrexate in Childhood ALL
Copenhagen University Hospital, Rigshospitalet 43 participants Est. completion 2013-01 1 siteOther conditions: Lymphoblastic Leukemia, Acute, ChildhoodView official trial listing → -
Completed NCT NCT01900431
Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis
Not yet reported Sanofi 58 participants Est. completion 2016-04 20 sites Stand-aloneOther conditions: UveitisView official trial listing → -
Withdrawn NCT NCT01903317
Evaluation of Vitamin D Levels in Psoriasis Patients
University of California, Irvine Est. completion 2015-07 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT01909427
An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Janssen Research & Development, LLC 257 participants Est. completion 2015-05 32 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01911234
Clinical Efficacy of TNF-Kinoid in Patients With Rheumatoid Arthritis
Not yet reported Neovacs 143 participants Est. completion 2014-09 31 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01913093
N-PhenoGENICS: Neurocognitive-Phenome, Genome, Epigenome and Nutriome In Childhood Leukemia Survivors
The Hospital for Sick Children 204 participants Est. completion 2019-06 1 siteOther conditions: Childhood Leukemia SurvivorsView official trial listing → -
Completed NCT NCT01914770
Effectiveness of Belimumab Treatment in a Subpopulation of Systemic Lupus Erythematosus (SLE) Patients: a Pooled Analysis of BLISS-52 and BLISS-76
GlaxoSmithKline 1016 participants Est. completion 2010-11Other conditions: Systemic Lupus ErythematosusView official trial listing → -
Status unknown NCT NCT01915537
Infliximab and Classic DMARDs in the Rheumatoid Arthritis Patients
Not yet reported Zhang, Xiao, M.D. 170 participants Est. completion 2017-12 3 sitesOther conditions: Rheumatoid Arthritis(RA)View official trial listing → -
Completed NCT NCT01918267
U-Act-After: An Observational Study on Long-Term Efficacy of Tight Control RoActemra/Actemra (Tocilizumab) and/or Methotrexate in Patients With Early Rheumatoid Arthritis Who Have Participated in the U-Act-Early Study (ML22497)
Hoffmann-La Roche 226 participants Est. completion 2017-10-10 19 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT01920737
A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 39 participants Est. completion 2027-08 3 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT01927484
Hand OA AND Methotrexate Use
Not yet reported University of Alexandria 2 participants Est. completion 2020-03-11 1 site Stand-aloneOther conditions: Reduction in Pain, Reduction of Inflammation, Improvement in FunctionView official trial listing → -
Terminated NCT NCT01927757
Evaluating Etanercept Use in Patients With Moderate to Severe Rheumatoid Arthritis Who Have Lost Response to Adalimumab
Not yet reported Amgen 90 participants Est. completion 2015-06-11 45 sites Stand-aloneOther conditions: Moderate to Severe Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01933282
MESA Treatment for NK/T Cell Lymphoma
Not yet reported Air Force Military Medical University, China 100 participants Est. completion 2015-01 1 site Stand-aloneOther conditions: Lymphoma, Extranodal NK-T-CellView official trial listing → -
Completed NCT NCT01936181
A Study Comparing SB2 to Remicade® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Samsung Bioepis Co., Ltd. 584 participants Est. completion 2015-09 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01941095
A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 100 participants Est. completion 2016-07-10 10 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01941940
A Study to Evaluate Efficacy of Tocilizumab Administered as Monotherapy or in Combination With Methotrexate and/or Other Disease Modifying Antirheumatic Drugs (DMARDs) in Rheumatoid Arthritis (RA) Participants
Not yet reported Hoffmann-La Roche 227 participants Est. completion 2016-07-05 49 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01942174
VACcination In Methotrexate Treated Rheumatoid Arthritis Patients
Not yet reported University Hospital, Montpellier 276 participants Est. completion 2019-07-10 21 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01943279
Comparison of Telephone Follow-up With In-person Follow-up After Medical Abortion
Not yet reported Women's College Hospital 139 participants Est. completion 2014-12 2 sitesOther conditions: Medical; Abortion, FetusView official trial listing → -
Completed NCT NCT01948388
The Effect of Corticotrophin (ACTH) in Combination With Methotrexate in Newly Diagnosed Rheumatoid Arthritis Patients
Not yet reported Gaylis, Norman B., M.D. 20 participants Est. completion 2016-09 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01949116
Safety and Effectiveness of Low-Dose Methotrexate for Reducing Inflammation in HIV-Infected Adults on ARV Medications
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 176 participants Est. completion 2016-12-08 22 sites Stand-aloneOther conditions: HIV InfectionsView official trial listing → -
Completed NCT NCT01951885
Tac, Mini-MTX, MMF Versus Tac, MTX for GVHD Prevention
Not yet reported Case Comprehensive Cancer Center 101 participants Est. completion 2021-08-11 1 site Stand-aloneOther conditions: Chronic Myelogenous Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Biphenotypic Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Non-Hodgkin Lymphoma, Hodgkins Disease, Chronic Lymphocytic Leukemia, Multiple MyelomaView official trial listing → -
Status unknown NCT NCT01953770
Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2008
Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 3000 participants Est. completion 2020-07 46 sites Stand-aloneOther conditions: Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01960283
Methotrexate in the Treatment of Chronic Idiopathic Urticaria
Not yet reported University Hospital, Tours 83 participants Est. completion 2016-05 11 sitesOther conditions: Chronic UrticariaView official trial listing → -
Completed NCT NCT01960855
A Study Investigating the Efficacy and Safety of ABT-494 Given With Methotrexate in Subjects With Rheumatoid Arthritis Who Failed Anti-Tumor Necrosis Factor (TNF) Biologic Therapy
Not yet reported AbbVie 276 participants Est. completion 2015-07Other conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT01964755
Chemotherapy for Relapsed Epstein Barr Virus Associated Lymphoma
Not yet reported University of Miami 6 participants Est. completion 2018-06-07 2 sites Stand-aloneOther conditions: Epstein Barr Virus Associated Non Hodgkin's Lymphoma, Epstein Barr Virus Associated Hodgkin's Lymphoma, Post-Transplant Lymphoproliferative DiseaseView official trial listing → -
Completed NCT NCT01975610
Efficacy and Safety Study of CC-292 Versus Placebo as Co-therapy With Methotrexate in Active Rheumatoid Arthritis
Not yet reported Celgene 47 participants Est. completion 2016-02 27 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01976182
Prospective, Multicentric, Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (methotrexate, Cyclophosphamide) in Large Granular Lymphocytes Leukemia
Not yet reported Rennes University Hospital 166 participants Est. completion 2024-10-07 59 sitesOther conditions: Large Granular Lymphocytes LeukemiaView official trial listing → -
Completed NCT NCT01976364
Open-Label Extension Study Of Tofacitinib In Psoriatic Arthritis
Not yet reported Pfizer 686 participants Est. completion 2019-05-20 153 sites Stand-aloneOther conditions: Arthritis, PsoriaticView official trial listing → -
Completed NCT NCT01979536
Brentuximab Vedotin or Crizotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage II-IV Anaplastic Large Cell Lymphoma
Not yet reported National Cancer Institute (NCI) 137 participants Est. completion 2024-03-31 154 sites Stand-aloneOther conditions: Anaplastic Large Cell Lymphoma, ALK-Positive, Ann Arbor Stage II Noncutaneous Childhood Anaplastic Large Cell Lymphoma, Ann Arbor Stage III Noncutaneous Childhood Anaplastic Large Cell Lymphoma, Ann Arbor Stage IV Noncutaneous Childhood Anaplastic Large Cell LymphomaView official trial listing → -
Completed NCT NCT01984099
RCT on the Efficacy of Methotrexate for the Prevention of GTD
Not yet reported University of the Philippines 99 participants Est. completion 2013-08 1 siteOther conditions: Hydatidiform MoleView official trial listing → -
Terminated NCT NCT01984268
ACTHAR for Acute Treatment of Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate
Not yet reported Dartmouth-Hitchcock Medical Center 15 participants Est. completion 2016-09-01 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01987102
Investigation of [6R] 5,10-methylenetetrahydrofolate (Arfolitixorin) as Rescue Therapy for Osteosarcoma Patients Treated With HDMTX.
Not yet reported, Not yet reported Isofol Medical AB 18 participants Est. completion 2017-01-03 5 sitesObstructive sleep apneaView official trial listing → -
Completed NCT NCT01987479
A Study on Safety and Efficacy of Tocilizumab (RoActemra/Actemra) Alone or in Combination With Non-Biologic Antirheumatics in Participants With Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 150 participants Est. completion 2016-05-26 20 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01990157
Safety, Tolerability, Pharmacodynamics and Efficacy Study of TAB08 in Patients With Rheumatoid Arthritis
Not yet reported, Not yet reported Theramab LLC 18 participants Est. completion 2017-02 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT01990807
Treatment Protocol of Children With Philadelphia Chromosome Negative High Risk Acute Lymphoblastic Leukemia
Not yet reported Chinese Academy of Medical Sciences 20 participants Est. completion 2014-10 1 siteOther conditions: Childhood Acute Lymphoblastic Leukemia, Philadelphia Chromosome, Ph^1^, Absent, B-cell Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT01991158
GAD-M Regimen As First-Line Treatment in Untreated Extranodal NK/T Cell Lymphoma
Not yet reported Sun Yat-sen University 30 participants Est. completion 2020-11 1 site Stand-aloneOther conditions: Extranodal NK/T-cell Lymphoma, Nasal TypeView official trial listing → -
Completed NCT NCT01995201
A Study of Subcutaneous RoActemra/Actemra (Tocilizumab) as Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Patients With Active Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 401 participants Est. completion 2016-03 53 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT01998906
A Study of Herceptin (Trastuzumab) in Combination Chemotherapy in Women With Locally Advanced Breast Cancer
Not yet reported Hoffmann-La Roche 330 participants Est. completion 2012-07 36 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT01999192
Study to Investigate the Safety and Efficacy of Tregalizumab in Subjects (MTX-IR) With Active Rheumatoid Arthritis
Not yet reported Biotest 321 participants Est. completion 2015-07 84 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02000336
Comparison of the Effectiveness of Two Different Dosages of Cortisone Compared to Placebo in Rheumatoid Arthritis
Not yet reported Prof. Dr. rer. nat. H.J. Trampisch 395 participants Est. completion 2019-09 25 sites Stand-aloneOther conditions: Progression of Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02001987
A Study of Tocilizumab (RoActemra) in Tocilizumab-Naive Participants With Rheumatoid Arthritis and Inadequate Response to Non-Biologic Disease-Modifying Antirheumatic Drugs (DMARDs) and/or Biologic Therapy
Not yet reported Hoffmann-La Roche 139 participants Est. completion 2015-12 32 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT02003222
Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 488 participants Est. completion 2027-02-25 544 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeView official trial listing → -
Completed NCT NCT02006706
A Study of MabThera/Rituxan (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis and Inadequate Response to DMARD Therapy
Not yet reported Hoffmann-La Roche 15 participants Est. completion 2007-11-23 3 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02011022
Pharmacokinetic Analysis of High Dose Methotrexate in Pediatric Lymphoblastic Malignancies
Not yet reported The Children's Hospital of Zhejiang University School of Medicine 291 participants Est. completion 2010-02 1 siteOther conditions: Methotrexate Adverse ReactionView official trial listing → -
Terminated NCT NCT02013167
Blinatumomab Versus Standard of Care Chemotherapy in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)
Not yet reported Amgen 405 participants Est. completion 2017-03-14 117 sitesOther conditions: Relapsed/Refractory B-precursor Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02015520
Phase IIB Dose Ranging Study in Subjects With Moderate to Severe Rheumatoid Arthritis
Not yet reported CSL Behring 143 participants Est. completion 2015-06 55 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02017964
Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma
Not yet reported Children's Oncology Group 26 participants Est. completion 2022-12-31 173 sites Stand-aloneOther conditions: Desmoplastic/Nodular Medulloblastoma, Medulloblastoma, Medulloblastoma With Extensive Nodularity, Nevoid Basal Cell Carcinoma SyndromeView official trial listing → -
Status unknown NCT NCT02020161
Clinical Guidelines for APL Treatment
Not yet reported PETHEMA Foundation 200 participants Est. completion 2021-12 1 site Stand-aloneOther conditions: APLView official trial listing → -
Terminated NCT NCT02022358
Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?
Not yet reported University College, London 34 participants Est. completion 2015-06 1 site Stand-aloneObstructive sleep apnea Other conditions: Spindle Cell Sarcoma of BoneView official trial listing → -
Status unknown NCT NCT02024334
Efficacy Study of Leflunomide to Treat Juvenile Idiopathic Arthritis
Not yet reported Mashhad University of Medical Sciences 30 participants Est. completion 2014-12 1 siteOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT02029599
The Efficacy and Safety of Fang yi Qing Feng Shi Granules in Subjects With Rheumatoid Arthritis
Not yet reported Maoxiang Group Jilin Pharmaceutical Co., Ltd. 240 participants 5 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02037191
The Efficiency Of The Methotrexate At Patients Affected By Grave Pelade
Not yet reported University Hospital, Rouen 90 participants Est. completion 2017-12 2 sitesOther conditions: ALOPECIA AREATAView official trial listing → -
Completed NCT NCT02037737
Impact and Use of Abatacept IV for Rheumatoid Arthritis in Real Life Setting
Bristol-Myers Squibb 153 participants Est. completion 2018-01-31Other conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT02043587
Chemotherapy With Liposomal Cytarabine CNS Prophylaxis for Adult Acute Lymphoblastic Leukemia & Lymphoblastic Lymphoma
Not yet reported University of California, San Diego 31 participants Est. completion 2022-04-14 4 sites Stand-aloneOther conditions: Acute Lymphocytic Leukemia, Adult Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT02045368
Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R
Not yet reported IGF Oncology, LLC 92 participants Est. completion 2016-09-30 1 site Stand-aloneOther conditions: Breast Cancer, Brain Cancer, Gastrointestinal Cancers, Genitourinary Cancers, Gynecologic Cancers, Head and Neck Cancers, Melanoma, Thoracic CancersView official trial listing → -
Completed NCT NCT02046603
A Study of Tocilizumab (RoActemra/Actemra) in Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Participants With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biologic DMARD Therapy or the First Anti-TNF Biologic Agent
Not yet reported Hoffmann-La Roche 162 participants Est. completion 2016-08-04 38 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02046616
A Study of Subcutaneous (SC) Tocilizumab (RoActemra/Actemra) in Participants With Active Rheumatoid Arthritis (RA) and Inadequate Response to Disease-Modifying Anti-Rheumatic Drugs (DMARDs)
Not yet reported Hoffmann-La Roche 133 participants Est. completion 2016-09-13 27 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02046694
A Pilot Study of Allopurinol As A Modifier of 6-MP Metabolism in Pediatric ALL
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 34 participants Est. completion 2020-04-06 3 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL)View official trial listing → -
Completed NCT NCT02052167
Human Factors Study of Methotrexate Prefilled Pen (50 mg/mL) in Patients With Juvenile Idiopathic Arthritis
Not yet reported medac GmbH 30 participants Est. completion 2014-08 1 site Stand-aloneOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT02052375
A Study To Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of ASP2408 After Multiple Dose Subcutaneous Injections in Patients With Rheumatoid Arthritis on Methotrexate
Not yet reported Astellas Pharma Global Development, Inc. 24 participants Est. completion 2013-12 3 sitesOther conditions: Rheumatoid Arthritis, Pharmacokinetics of ASP2408View official trial listing → -
Status unknown NCT NCT02054442
A Study of the Combination of Cetuximab and Methotrexate in Recurrent or Metastatic Cancer of the Head and Neck
Not yet reported, Not yet reported Radboud University Medical Center 52 participants Est. completion 2022-12 8 sites Stand-aloneOther conditions: Squamous Cell Carcinoma of the Head and NeckView official trial listing → -
Completed NCT NCT02057250
To Evaluate Sarilumab - SAR153191 (REGN88) - Auto-injector Device In Patients With Rheumatoid Arthritis
Not yet reported Sanofi 217 participants Est. completion 2016-03 53 sites Stand-aloneOther conditions: RAView official trial listing → -
Completed NCT NCT02065700
Long-term Follow-up Study of GLPG0634 in Active Rheumatoid Arthritis Participants
Not yet reported Lakefront Biotherapeutics NV 739 participants Est. completion 2023-01-19 111 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02065713
Efficacy of Golimumab in Combination With Methotrexate (MTX) Versus MTX Monotherapy, in Improving Dactylitis, in MTX naïve Psoriatic Arthritis Patients
Not yet reported Instituto de Medicina Molecular João Lobo Antunes 44 participants Est. completion 2017-06 1 site Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT02066389
A Study Investigating the Efficacy and Safety of Upadacitinib (ABT-494) Given With Methotrexate (MTX) in Adults With Rheumatoid Arthritis Who Have Had an Inadequate Response to MTX Alone
Not yet reported AbbVie 300 participants Est. completion 2015-07-02 63 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02067143
MRD/Risk-oriented Therapy of Adult Ph- ALL Including Pegylated Asparaginase and Lineage-targeted Methotrexate
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 204 participants Est. completion 2020-12-07 61 sitesOther conditions: Untreated Philadelphia Positive Acute Lymphoblastic Leukemia, De Novo, Secondary, Low-dose Corticosteroids PretreatmentView official trial listing → -
Completed NCT NCT02074319
RCT of Methotrexate Added to Treatment As Usual in Schizophrenia
Not yet reported Pakistan Institute of Living and Learning 92 participants Est. completion 2015-08 4 sites Stand-aloneOther conditions: Schizophrenia, Schizoaffective Disorder, Schizophreniform DisorderView official trial listing → -
Status unknown NCT NCT02075697
Spanish Registry of Systemic Treatments in Psoriasis
Fundación Academia Española de Dermatología 3500 participants Est. completion 2025-10 13 sitesOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT02076659
Combination Therapy of F8IL10 and Methotrexate in Rheumatoid Arthritis Patients
Not yet reported Philogen S.p.A. 36 participants Est. completion 2017-04-13 5 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02076997
Individualized High Dose Methotrexate to Treat Cancer in Children Who Have a Significant Risk for Side Effects to Methotrexate
Not yet reported Baylor College of Medicine 23 participants Est. completion 2019-05-10 1 site Stand-aloneOther conditions: CancerView official trial listing → -
Withdrawn NCT NCT02079948
Inflammation Control For Elders: ICE Study
Not yet reported University of Florida Est. completion 2014-09 Stand-aloneOther conditions: Inflammation, AgingView official trial listing → -
Status unknown NCT NCT02085655
PEG-ASP+Gemox Regimen and Thalidomide for NK/T Lymphoma
Not yet reported Huiqiang Huang 264 participants Est. completion 2022-12-31 1 siteOther conditions: Extranodal NK-T-Cell Lymphoma, Nasal and Nasal-TypeView official trial listing → -
Status unknown NCT NCT02087696
Uncontrolled Study to Evaluate Efficacy of Tocilizumab in Patients With Moderate or Severe Rheumatoid Arthritis
Not yet reported Spanish Foundation of Rheumatology 122 participants Est. completion 2016-07 20 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT02093026
Extension Study to Assess the Efficacy and Safety of Repeat Treatment With Rituximab (MabThera) in Participants With Active Rheumatoid Arthritis (RA)
Not yet reported Hoffmann-La Roche 465 participants Est. completion 2012-12 92 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02097173
Bioavailability in Patient With Psoriasis: Metoject Prefilled Pen
Not yet reported medac GmbH 35 participants 1 siteOther conditions: PsoriasisView official trial listing → -
Withdrawn NCT NCT02097264
A Trial Investigating the Mechanism of Action of NNC0109-0012 (Anti-IL-20 mAb) Through Synovial Biopsies in Subjects With Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Not yet reported Novo Nordisk A/S Est. completion 2015-09Other conditions: Inflammation, Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02097524
Single-dose Study to Describe the Pharmacodynamics (PD) and Safety of Sarilumab (REGN88/SAR153191) and Tocilizumab in Adults With Rheumatoid Arthritis (RA)
Not yet reported Regeneron Pharmaceuticals 105 participants Est. completion 2015-04 19 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02097745
A Study of the Efficacy and Safety of Re-treatments With Rituximab in Patients With Active Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-tnfa Therapies
Not yet reported Hoffmann-La Roche 341 participants Est. completion 2013-06 97 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT02101853
Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 669 participants Est. completion 2026-09-16 186 sites Stand-aloneOther conditions: Recurrent B Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02105636
Trial of Nivolumab vs Therapy of Investigator's Choice in Recurrent or Metastatic Head and Neck Carcinoma (CheckMate 141)
Not yet reported Bristol-Myers Squibb 361 participants Est. completion 2021-09-10 64 sitesOther conditions: Squamous Cell Carcinoma of the Head and NeckView official trial listing → -
Terminated NCT NCT02109289
Etanercept in Rheumatoid Arthritis and Vascular Inflammation
Not yet reported Innovaderm Research Inc. 5 participants Est. completion 2016-11 1 site Stand-aloneOther conditions: Rheumatoid Arthritis, Vascular InflammationView official trial listing → -
Active, not recruiting NCT NCT02112916
Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma
Not yet reported National Cancer Institute (NCI) 847 participants Est. completion 2026-09-16 212 sites Stand-aloneOther conditions: Adult T Acute Lymphoblastic Leukemia, Ann Arbor Stage II Adult Lymphoblastic Lymphoma, Ann Arbor Stage II Childhood Lymphoblastic Lymphoma, Ann Arbor Stage III Adult Lymphoblastic Lymphoma, Ann Arbor Stage III Childhood Lymphoblastic Lymphoma, Ann Arbor Stage IV Adult Lymphoblastic Lymphoma, Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma, Childhood T Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT02114229
Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors
Not yet reported St. Jude Children's Research Hospital 125 participants Est. completion 2027-09 9 sites Stand-aloneOther conditions: Malignant Rhabdoid Tumor, Atypical Teratoid Rhabdoid TumorView official trial listing → -
Completed NCT NCT02115204
4 x Epirubicin, Cyclophosphamide, Followed by 4 x Docetaxel Versus 6 x CMF / 6 x CEF
Not yet reported Women's Cancer Study Group GmbH 2011 participants Est. completion 2010-08 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02115750
Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Rheumatoid Arthritis (RA)
Not yet reported Coherus Oncology, Inc. 647 participants Est. completion 2016-05 141 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02122081
Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies
Not yet reported Sumithira Vasu 33 participants Est. completion 2022-09-06 1 site Stand-aloneOther conditions: Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT02124226
Low-dose Methotrexate for Change in Global Initiative for Asthma Step 5 Medications in Chronic Severe Asthma
Not yet reported University of Catania 102 participants Est. completion 2022-07 Stand-aloneOther conditions: Low Dose Methotrexate in Severe Chronic AsthmaView official trial listing → -
Terminated NCT NCT02125266
Safety and Preliminary Efficacy Study of V404 PDS in Uveitis
Not yet reported, Not yet reported Forsight Vision4 7 participants Est. completion 2015-03 5 sites Stand-aloneOther conditions: Uveitis, Posterior, Uveitis, IntermediateView official trial listing → -
Completed NCT NCT02129582
Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignancies
Not yet reported Case Comprehensive Cancer Center 14 participants Est. completion 2020-03-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Hematologic Malignancies, Acute Lymphocytic Leukemia, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Myelodysplastic Syndrome, Chronic Lymphocytic Leukemia, Chronic Myeloid Leukemia, Myelofibrosis, Myeloproliferative SyndromeView official trial listing → -
Completed NCT NCT02133599
Prediction of Excretion and Toxicity of High Dose Methotrexate in Children and Adolescents With ALL
Not yet reported Ann & Robert H Lurie Children's Hospital of Chicago 23 participants Est. completion 2019-02-27 1 siteOther conditions: ALLView official trial listing → -
Withdrawn NCT NCT02141100
Study of 6-Thioguanine in Combination With 6-Mercaptopurine During Maintenance Therapy of Childhood Lymphoma
Not yet reported, Not yet reported Kjeld Schmiegelow Est. completion 2016-10 1 site Stand-aloneOther conditions: Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT02141997
A Study to Investigate the Safety and Efficacy of ABT-122 Given With Methotrexate in Subjects With Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate
Not yet reported AbbVie 222 participants Est. completion 2015-11Other conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT02143414
Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 53 participants Est. completion 2027-06-06 195 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Recurrent Acute Lymphoblastic Leukemia, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02147587
A Study to Assess Immune Response Following Zoster Vaccination to Subjects With Rheumatoid Arthritis Receiving Tofacitinib or Placebo With Background Methotrexate
Not yet reported Pfizer 112 participants Est. completion 2015-07 36 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT02150473
The Effect of Adalimumab Plus Methotrexate (MTX) Versus Placebo Plus MTX on Cartilage in (RA) Patients
Not yet reported Heinrich-Heine University, Duesseldorf 21 participants Est. completion 2017-09-14 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02151851
A Study of Certolizumab Pegol as Additional Therapy in Chinese Patients With Active Rheumatoid Arthritis
Not yet reported UCB Pharma SA, Belgium 430 participants Est. completion 2016-06 30 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02152696
Optimal Treatment for Women With a Persisting Pregnancy of Unknown Location
Not yet reported Yale University 255 participants Est. completion 2019-08-19 17 sitesOther conditions: Persistent Pregnancy of Unknown Location, Ectopic PregnancyView official trial listing → -
Completed NCT NCT02162472
Videocapillaroscopy Assessment During Systemic Agent Therapy in Psoriasis
Northwestern University 19 participants Est. completion 2021-12-31 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT02167139
A Study Comparing SB5 to Humira® in Subjects With Moderate to Severe Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported Samsung Bioepis Co., Ltd. 544 participants Est. completion 2015-10 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02171143
A Dose Escalation Study to Assess Safety, Tolerability and Pharmacokinetics of ASP2409 Following a Single Intravenous Dose in Patients With Rheumatoid Arthritis on Methotrexate
Not yet reported Astellas Pharma Global Development, Inc. 58 participants Est. completion 2014-04 10 sitesOther conditions: Rheumatoid Arthritis, Pharmacokinetics of ASP2409View official trial listing → -
Status unknown NCT NCT02174354
Methotrexate Polyglutamates as a Marker of Clinical Response and Toxicity in the Treatment of Psoriasis
King's College London 350 participants Est. completion 2018-08 1 siteOther conditions: Psoriasis Chronic, Injury of LiverView official trial listing → -
Completed NCT NCT02177071
A proSpective Randomized Controlled Trial comParing infliximAb-antimetabolites Combination Therapy to Anti-metabolites monotheRapy and Infliximab monothErapy in Crohn's Disease Patients in Sustained Steroid-free Remission on Combination Therapy
Not yet reported Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives 211 participants Est. completion 2021-10 27 sitesOther conditions: Crohn's DiseaseView official trial listing → -
Completed NCT NCT02177695
S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer
Not yet reported SWOG Cancer Research Network 237 participants Est. completion 2022-12-01 566 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT02187055
An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With Methotrexate
Not yet reported Pfizer 1152 participants Est. completion 2016-12 215 sites Stand-aloneOther conditions: Rhematoid ArthritisView official trial listing → -
Status unknown NCT NCT02188017
Acthar Gel for Chronic Pulmonary Sarcoidosis (ACPS)
Not yet reported University of Cincinnati 20 participants Est. completion 2017-09 1 siteOther conditions: Sarcoidosis, Pulmonary SarcoidosisView official trial listing → -
Completed NCT NCT02196480
23-valent Polysaccharide Pneumococcal Vaccine in Juvenile Idiopathic Arthritis Patients Under Anti-TNF Therapy
Not yet reported University of Sao Paulo 27 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT02196701
Concomitant Longitudinal Evaluation of Adalimumab With Methotrexate in the Real World: the CLEAR Study
Not yet reported AbbVie 46 participants Est. completion 2017-03-17 Stand-aloneOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT02200978
A Study for Improving the Outcome of Childhood Acute Promyeloid Leukemia
Not yet reported South China Children's Leukemia Group 176 participants Est. completion 2021-10 1 siteOther conditions: Childhood Acute Promyelocytic LeukemiaView official trial listing → -
Completed NCT NCT02202395
Hydroxytriptolide in Active Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate
Not yet reported, Not yet reported Shanghai Pharmaceuticals Holding Co., Ltd 120 participants Est. completion 2016-12-28 5 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT02203526
Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphoma
Not yet reported National Cancer Institute (NCI) 68 participants Est. completion 2028-06-15 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Active, not recruiting NCT NCT02205762
LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
Not yet reported, Not yet reported North American Consortium for Histiocytosis 1400 participants Est. completion 2026-07 42 sites Stand-aloneOther conditions: Langerhans Cell HistiocytosisView official trial listing → -
Completed NCT NCT02206035
A Study of Tacrolimus/Methotrexate and Tocilizumab to Prevent Acute Graft-Versus-Host Disease (AGVD) After Allogeneic Hematopoietic Stem Cell Transplant
Not yet reported William R. Drobyski, MD 45 participants Est. completion 2018-09 1 site Stand-aloneOther conditions: Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT02208037
Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 279 participants Est. completion 2017-10 30 sites Stand-aloneOther conditions: Acute Leukemia, Chronic Myelogenous Leukemia, Myelodysplasia, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Lymphoma, B-Cell, Lymphoma, Follicular, Lymphoma, Large B-Cell, Diffuse, Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT02212561
Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome
Not yet reported St. Jude Children's Research Hospital 19 participants Est. completion 2015-12 6 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Myelodysplastic Syndrome (MDS), Mixed Phenotype Acute Leukemia (MPAL)View official trial listing → -
Completed NCT NCT02219347
Biomarkers of Remission in Rheumatoid Arthritis (BioRRA)
Not yet reported Newcastle-upon-Tyne Hospitals NHS Trust 74 participants Est. completion 2017-08 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02220985
Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD
Not yet reported Fred Hutchinson Cancer Center 84 participants Est. completion 2025-05-01 2 sites Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Leukemia of Ambiguous Lineage, Acute Undifferentiated Leukemia, Allogeneic Hematopoietic Stem Cell Transplant Recipient, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Blastic Plasmacytoid Dendritic Cell Neoplasm, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Donor, Lymphoblastic Lymphoma, Myelodysplastic Syndrome With Excess Blasts, Myelodysplastic Syndrome With Excess Blasts-1, Myelodysplastic Syndrome With Excess Blasts-2, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in RemissionView official trial listing → -
Completed NCT NCT02222493
A Study of PF-06438179 (Infliximab-Pfizer) and Infliximab in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (REFLECTIONS B537-02).
Not yet reported Pfizer 650 participants Est. completion 2017-06-01 184 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02228772
Phase I Study of MLN 9708 in Addition to Chemotherapy for the Treatment of Acute Lymphoblastic Leukemia in Older Adults
Not yet reported Massachusetts General Hospital 19 participants Est. completion 2019-11 3 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, B-cell Adult Acute Lymphoblastic Leukemia, T-cell Adult Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT02242474
Anti-TNFα Use During Elective Foot and Ankle Surgery in Patients With Rheumatoid Arthritis
Not yet reported CHU de Quebec-Universite Laval 660 participants Est. completion 2019-10 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02248792
Quality of Life of Patients With Psoriasis Treated With Methotrexate: Prospective, Randomized, Double-blind, Parallel Group Study.
Not yet reported Narayana Medical College & Hospital 50 participants 1 site Stand-aloneOther conditions: Severe Plaque Type PsoriasisView official trial listing → -
Completed NCT NCT02251821
JAK Inhibitor Before Donor Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis
Not yet reported Fred Hutchinson Cancer Center 61 participants Est. completion 2026-01-22 1 site Stand-aloneOther conditions: Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Completed NCT NCT02252042
Pembrolizumab (MK-3475) Versus Standard Treatment for Recurrent or Metastatic Head and Neck Cancer (MK-3475-040/KEYNOTE-040)
Not yet reported Merck Sharp & Dohme LLC 495 participants Est. completion 2022-08-15Other conditions: Head and Neck Squamous Cell CancerView official trial listing → -
Completed NCT NCT02260791
A Study to Compare FKB327 Efficacy and Safety With Humira® in Rheumatoid Arthritis Patients
Not yet reported Fujifilm Kyowa Kirin Biologics Co., Ltd. 728 participants Est. completion 2016-07 100 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT02265705
A Study of Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis (RA)
Not yet reported Eli Lilly and Company 290 participants Est. completion 2017-05 30 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02269358
Salvage Therapy With High/Low Methotrexate for Loss of Response to Infliximab Dose Escalation
Not yet reported Prof. Arie Levine 22 participants Est. completion 2018-10-09 1 site Stand-aloneOther conditions: Crohn's DiseaseView official trial listing → -
Terminated NCT NCT02270632
A Randomized, Placebo-controlled Phase II Clinical Trial to Evaluate the Safety and Efficacy of F8IL10 (Dekavil) in Patients With Active RA Receiving MTX
Not yet reported Philogen S.p.A. 27 participants Est. completion 2023-06-08 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02270788
Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies
Not yet reported St. Jude Children's Research Hospital 10 participants Est. completion 2016-10-17 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02271971
Effect of Vitamin D Supplementation on Metabolic Parameters of Patients With Psoriasis
Not yet reported Pontificia Universidad Catolica de Chile 39 participants Est. completion 2015-10 1 siteMetabolic syndrome Other conditions: Psoriasis, Vitamin D DeficiencyView official trial listing → -
Status unknown NCT NCT02273583
Prospective Clinical Trial Evaluating Metronomic Chemotherapy in Patients With High-grade, Operable, Non-metastatic Osteosarcoma of the Extremity
Not yet reported Grupo de Apoio ao Adolescente e a Crianca com Cancer 738 participants 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Status unknown NCT NCT02275299
Study of Iguratimod Plus Methotrexate Compared to Leflunomid Plus Methotrexate in Patients With Rheumatoid Arthritis
Not yet reported Jiangsu Simcere Pharmaceutical Co., Ltd. 240 participants Est. completion 2016-02 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02277444
A Study to Evaluate the Pharmacokinetics, Efficacy and Safety of Intravenous Golimumab in Pediatric Participants With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate Therapy
Not yet reported Janssen Research & Development, LLC 130 participants Est. completion 2024-09-27 38 sites Stand-aloneOther conditions: Arthritis, JuvenileView official trial listing → -
Completed NCT NCT02280694
Low Dose Metronomic Poly-chemotherapy for Metastatic CRC
Not yet reported HaEmek Medical Center, Israel 45 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Completed NCT NCT02281552
A Study To Evaluate The Safety And Efficacy Of Tofacitinib Modified Release Tablets Compared To Tofacitinib Immediate Release Tablets In Adult Patients With Rheumatoid Arthritis
Not yet reported Pfizer 209 participants Est. completion 2017-03-15 36 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02287922
A Phase IIb Study for ALX-0061 Monotherapy in Subjects With Rheumatoid Arthritis
Not yet reported Ablynx, a Sanofi company 251 participants Est. completion 2016-07 83 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02288520
Therapeutic Strategy in Patients Treated With Methotrexate for Rheumatoid Arthritis
Nordic Pharma SAS 854 participants Est. completion 2016-03 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02293109
Carfilzomib and Hyper-CVAD in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoma
Not yet reported Mehrdad Abedi, MD 10 participants Est. completion 2018-01-11 1 site Stand-aloneOther conditions: Contiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Untreated Adult Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT02293681
An Observational Study of Infliximab in Participants Suffering From Ankylosing Spondylitis With Hip Involvement
Janssen Research & Development, LLC 76 participants Est. completion 2017-05-31 6 sitesOther conditions: Spondylitis, AnkylosingView official trial listing → -
Completed NCT NCT02293902
A Study Assessing the Efficacy and Safety of Sarilumab Added to MTX in Japanese Patients With Moderately to Severely Active Rheumatoid Arthritis (SARIL-RA-KAKEHASI)
Not yet reported Sanofi 243 participants Est. completion 2016-10 96 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02297126
A Prospective Trial to Assess Cost and Clinical Outcomes of a Clinical Pharmacogenomic Program
Not yet reported Indiana University 4465 participants Est. completion 2019-05-03 1 siteOther conditions: Adverse Drug ReactionView official trial listing → -
Active, not recruiting NCT NCT02299999
SAFIR02_Breast - Efficacy of Genome Analysis as a Therapeutic Decision Tool for Patients With Metastatic Breast Cancer
Not yet reported UNICANCER 1460 participants Est. completion 2025-12 25 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT02303821
Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported Amgen 141 participants Est. completion 2024-06-28 122 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL)View official trial listing → -
Completed NCT NCT02305849
A Study to Evaluate Efficacy and Safety of ASP015K in Patients With Rheumatoid Arthritis (RA) Who Had an Inadequate Response to Methotrexate (MTX) Treatment
Not yet reported Astellas Pharma Inc 519 participants Est. completion 2017-11-28 146 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02309359
A Dose-Range Finding Study for ALX-0061 Combination Therapy in Subjects With Rheumatoid Arthritis
Not yet reported Ablynx, a Sanofi company 345 participants Est. completion 2016-08 94 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02312219
PET/CT Imaging Companion Study To ACTG A5314
Massachusetts General Hospital 35 participants Est. completion 2016-12-08 1 siteOther conditions: HIV, Inflammation, AtherosclerosisView official trial listing → -
Status unknown NCT NCT02313389
Maintenance Treatment Versus Observation in Elderly Patients With PCNS Lymphoma
Not yet reported Assistance Publique - Hôpitaux de Paris 428 participants Est. completion 2023-04 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT02313870
Topical Steroids Alone or Associated With Methotrexate in Bullous Pemphigoid
Not yet reported University Hospital, Montpellier 322 participants Est. completion 2015-12-31 1 site Stand-aloneOther conditions: Bullous PemphigoidView official trial listing → -
Completed NCT NCT02313922
Optimizing Psoriasis Treatment of Etanercept Combined Methotrexate
Not yet reported Zhejiang University 466 participants Est. completion 2018-08 1 site Stand-aloneOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT02315326
Bruton's Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Patients With Newly Diagnosed or Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)
Not yet reported, Not yet reported Memorial Sloan Kettering Cancer Center 93 participants Est. completion 2026-01-28 7 sites Stand-aloneOther conditions: Adult Patients With Newly Diagnosed or Relapsed or Refractory Primary Central Nervous System Lymphoma (PCNSL), Or Relapsed or Refractory Secondary Central Nervous System Lymphoma (SCNSL)View official trial listing → -
Completed NCT NCT02319642
An Open-label Extension Study of Certolizumab Pegol in Chinese Patients With Rheumatoid Arthritis Who Enrolled in RA0044
Not yet reported UCB Pharma SA 347 participants Est. completion 2016-12 30 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02320630
Combination Therapy Prevents the Relapse of RA
Not yet reported Peking University First Hospital 240 participants Est. completion 2020-09 1 siteOther conditions: Recurrence (Disease Attribute)View official trial listing → -
Terminated NCT NCT02323659
Comparison of Methotrexate Versus Interferon-alfa 2b in Patients With Primary Cutaneous T-cell Lymphomas
Not yet reported Polish Lymphoma Research Group 100 participants Est. completion 2018-03-31 1 siteOther conditions: Lymphoma, T-Cell, Cutaneous, Mycosis FungoidesView official trial listing → -
Completed NCT NCT02328755
Peginterferon Alfa-2a to Enhance Anti-leukemic Responses After Allogeneic Transplantation in Acute Myeloid Leukemia
Not yet reported, Not yet reported University of Michigan Rogel Cancer Center 37 participants Est. completion 2019-03-25 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02329080
New Combination of Chemoimmunotherapy for Systemic B-cell Lymphoma With Central Nervous System Involvement
Not yet reported International Extranodal Lymphoma Study Group (IELSG) 79 participants Est. completion 2024-03-22 36 sites Stand-aloneOther conditions: Diffuse Large B-cell LymphomaView official trial listing → -
Completed NCT NCT02330380
Comparative Effectiveness of Psoriasis Treatments on Systemic Inflammation
University Hospitals Cleveland Medical Center 26 participants Est. completion 2016-12 1 siteOther conditions: Psoriasis, InflammationView official trial listing → -
Status unknown NCT NCT02339350
Treatment of Newly Diagnosed High Risk Acute Lymphoblastic Leukemia in Children
Not yet reported The Korean Society of Pediatric Hematology Oncology 110 participants Est. completion 2023-04 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, ChildView official trial listing → -
Completed NCT NCT02339441
Treatment Outcome in Early Diffuse Cutaneous Systemic Sclerosis
University of Manchester 320 participants Est. completion 2016-03Other conditions: Early Diffuse Cutaneous Systemic SclerosisView official trial listing → -
Completed NCT NCT02342145
Efficacy of Basiliximab in the Prevention of Acute Graft-versus-host Disease in Unrelated Allogeneic Hematopoietic Stem Cell Transplantation Therapy for Thalassemia Major
Not yet reported Zhongming Zhang 205 participants Est. completion 2022-08-20 3 sites Stand-aloneOther conditions: Beta-Thalassemia Major, Graft-versus-host Disease (GVHD)View official trial listing → -
Completed NCT NCT02345850
Calcineurin Inhibitor-Free Interventions BMT CTN 1301 for Prevention of Graft-versus-Host Disease (BMT CTN 1301)
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 346 participants Est. completion 2020-10-05 28 sitesOther conditions: Acute Leukemia, MyelodysplasiaView official trial listing → -
Completed NCT NCT02347332
Phase III Study of Vinflunine Plus Methotrexate Versus Methotrexate Alone in Patients With Head and Neck Cancer
Not yet reported Pierre Fabre Medicament 459 participants Est. completion 2018-11-23 1 site Stand-aloneOther conditions: Recurrent or Metastatic Head and Neck CarcinomaView official trial listing → -
Completed NCT NCT02349061
A Phase 2a, Efficacy and Safety Study of Ustekinumab in Systemic Lupus Erythematosus
Not yet reported Janssen Research & Development, LLC 102 participants Est. completion 2019-03-13 43 sites Stand-aloneOther conditions: Lupus Erythematosus, SystemicView official trial listing → -
Completed NCT NCT02349451
A Phase 2 Study to Investigate the Safety, Tolerability and Efficacy of ABT-122 in Subjects With Active Psoriatic Arthritis (PsA) Who Have an Inadequate Response to Methotrexate (MTX)
Not yet reported AbbVie 240 participants Est. completion 2016-07-04Other conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT02356159
Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation
Not yet reported, Not yet reported National Cancer Institute (NCI) 34 participants Est. completion 2025-03-25 2 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Acute Leukemia, Multiple MyelomaView official trial listing → -
Status unknown NCT NCT02356445
Use of Immunosuppressive Therapy for Sarcoidosis
University of Cincinnati 2000 participants Est. completion 2018-12 1 siteOther conditions: SarcoidosisView official trial listing → -
Status unknown NCT NCT02357069
A Study Comparing LBEC0101 to Enbrel® in Subjects With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported LG Life Sciences 372 participants 2 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT02366091
Inflammation and Coronary Endothelial Function
Not yet reported Johns Hopkins University 111 participants Est. completion 2020-09-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02373579
Effect of Omega-3 Fatty Acids on Methotrexate Induced Hepatotoxicity in Children With Acute Lymphoblastic Leukemia
Not yet reported Nancy Samir Elbarbary 70 participants Est. completion 2014-10Other conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02373813
Study of Etanercept Monotherapy vs Methotrexate Monotherapy for Maintenance of Rheumatoid Arthritis Remission
Not yet reported Amgen 371 participants Est. completion 2019-12-06 136 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02374021
Treatments Against RA and Effect on FDG-PET/CT
Not yet reported Brigham and Women's Hospital 159 participants Est. completion 2021-05 31 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT02376478
On the Impact of Therapeutic Tumor Necrosis Factor-alpha Inhibition on Anogenital Human Papillomavirus Infection
Medical University of Vienna 222 participants Est. completion 2011-01Other conditions: Psoriasis, Inflammatory Bowel DiseasesView official trial listing → -
Completed NCT NCT02376790
Etanercept and Methotrexate in Combination or as Monotherapy in Psoriatic Arthritis
Not yet reported Amgen 851 participants Est. completion 2018-07-06 138 sites Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT02378298
Rituximab (RTX) Therapy in Patients With Active TAO
Not yet reported Göteborg University 38 participants Est. completion 2020-02-01 5 sitesOther conditions: Ophthalmopathy, Thyroid-AssociatedView official trial listing → -
Completed NCT NCT02379091
Dose Finding Study of Namilumab in Combination With Methotrexate in Participants With Moderate to Severe Rheumatoid Arthritis (RA)
Not yet reported Takeda 108 participants Est. completion 2016-12-05 31 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02383680
Yellow Fever Vaccination Under Low Dose Methotrexate Therapy
University of Zurich 30 participants Est. completion 2016-06 6 sitesOther conditions: Rheumatic, Dermatologic DisordersView official trial listing → -
Completed NCT NCT02383901
A Retrospective Non-intervention Study to Characterize FOlate Rescue Treatment in Osteosarcoma Patients Treated With HDMTX
Isofol Medical AB 116 participants Est. completion 2016-05 5 sitesObstructive sleep apneaView official trial listing → -
Completed NCT NCT02385110
Alemtuzumab or Tocilizumab in Combination With Etoposide and Dexamethasone for the Treatment of Adult Patients With Hemophagocytic Lymphohistiocytosis
Not yet reported M.D. Anderson Cancer Center 18 participants Est. completion 2023-01-24 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT02387762
ACP-196 Versus Placebo in Subjects With Rheumatoid Arthritis on Background Methotrexate
Not yet reported Acerta Pharma BV 31 participants Est. completion 2016-06 17 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02389400
Methotrexate and Cytosine in Adult Langerhans Cell Histiocytosis
Not yet reported Peking Union Medical College Hospital 43 participants Est. completion 2017-09 1 site Stand-aloneOther conditions: Langerhans Cell HistiocytosisView official trial listing → -
Terminated NCT NCT02393378
Namilumab vs Adalimumab in Participants With Moderate to Severe Early Rheumatoid Arthritis Inadequately Responding to Methotrexate
Not yet reported Takeda 7 participants Est. completion 2016-11-16 13 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02393859
Phase 3 Trial of Blinatumomab vs Standard Chemotherapy in Pediatric Subjects With HIgh-Risk (HR) First Relapse B-precursor Acute Lymphoblastic Leukemia (ALL)
Not yet reported Amgen 111 participants Est. completion 2022-11-21 103 sitesOther conditions: Leukemia, Acute LymphoblasticView official trial listing → -
Status unknown NCT NCT02396043
Modified BFM-95 Regimen as First-Line Chemotherapy in Adults With T- Lymphoblastic Lymphoma
Not yet reported Sun Yat-sen University 50 participants Est. completion 2025-03 1 site Stand-aloneOther conditions: Lymphoma, LymphoblasticView official trial listing → -
Status unknown NCT NCT02399189
MT-R Followed by Autologous Stem Cells Transplantation in Newly-diagnosed Primary Central Nervous System Lymphoma
Not yet reported Jun Zhu 39 participants Est. completion 2019-04 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Active, not recruiting NCT NCT02405676
BNHL-2015 for Children or Adolescents in China
Not yet reported, Not yet reported Children's Cancer Group, China 200 participants Est. completion 2029-12 1 siteOther conditions: Mature B-cell Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT02405780
A Study to Compare FKB327 Long-term Safety, Efficacy and Immunogenicity With Humira® in Rheumatoid Arthritis Patients
Not yet reported Fujifilm Kyowa Kirin Biologics Co., Ltd. 645 participants Est. completion 2018-01-18 92 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT02412670
Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer
Not yet reported ECOG-ACRIN Cancer Research Group 36 participants Est. completion 2022-05-10 134 sites Stand-aloneOther conditions: High Grade Upper Tract Urothelial CarcinomaView official trial listing → -
Terminated NCT NCT02413047
Evaluate if Response to Infliximab or Adalimumab May be Regained With an Immunomodulator
Not yet reported Indiana University 3 participants Est. completion 2018-02 1 site Stand-aloneOther conditions: Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's DiseaseView official trial listing → -
Terminated NCT NCT02419469
Augmented Berlin-Frankfurt-Munster Therapy Plus Ofatumumab for Young Adults With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Not yet reported M.D. Anderson Cancer Center 1 participants Est. completion 2017-06-22 1 site Stand-aloneOther conditions: Leukemia, Precursor-B Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, LymphomaView official trial listing → -
Terminated NCT NCT02419755
Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies
Not yet reported St. Jude Children's Research Hospital 12 participants Est. completion 2016-12-31 1 site Stand-aloneOther conditions: Mixed Lineage Acute Leukemia, Acute Myeloid Leukemia, Acute Lymphoid LeukemiaView official trial listing → -
Terminated NCT NCT02420717
Ruxolitinib Phosphate or Dasatinib With Chemotherapy in Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center 11 participants Est. completion 2021-01-20 1 site Stand-aloneOther conditions: Recurrent B Acute Lymphoblastic Leukemia, Recurrent Ph-Like Acute Lymphoblastic Leukemia, Refractory B Acute Lymphoblastic Leukemia, Refractory Ph-Like Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT02427620
Ibrutinib, Rituximab, and Consolidation Chemotherapy in Treating Young Patients With Newly Diagnosed Mantle Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 131 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Blastoid Variant Mantle Cell Lymphoma, Mantle Cell Lymphoma, Pleomorphic Variant Mantle Cell LymphomaView official trial listing → -
Terminated NCT NCT02429895
A Phase 2, Multicenter Open-Label Extension (OLE) Study With ABT-122 in Active Psoriatic Arthritis Subjects Who Have Completed a Preceding Study M14-197
Not yet reported AbbVie 168 participants Est. completion 2016-05 36 sitesOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT02433184
Very Early Versus Delayed Etanercept in Patients With RA
Not yet reported University of Leeds 120 participants Est. completion 2019-07 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02433340
Phase 2, Multicenter, Open-Label Extension Study With ABT-122 in Rheumatoid Arthritis Subjects Who Have Completed the Preceding M12-963 Study
Not yet reported AbbVie 158 participants Est. completion 2016-05Other conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT02433483
Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients
Not yet reported St. Jude Children's Research Hospital 4 participants Est. completion 2017-05-08 1 siteOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)View official trial listing → -
Completed NCT NCT02434133
Cross Sectional Study of Vaccine Antibody Response in Inflammatory Bowel Disease Patients
University of Wisconsin, Madison 110 participants Est. completion 2017-12 1 siteOther conditions: Inflammatory Bowel Disease (IBD)View official trial listing → -
Completed NCT NCT02440464
Allogeneic Hematopoietic Stem Cell Transplantation With Ixazomib for High Risk Multiple Myeloma (BMT CTN 1302)
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 57 participants Est. completion 2020-10-01 15 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT02451748
IL-7 and IL-7R Expression in RA Patients With Active vs. Inactive Disease Treated With DMARD or CIMZIA
Not yet reported University of Illinois at Chicago 32 participants Est. completion 2017-12 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02451774
Pentoxifylline In Pediatric Acute Lymphoblastic Leukemia During Induction
Not yet reported, Not yet reported Ramón Óscar González-Ramella, Ph.D 44 participants Est. completion 2020-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02456844
Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy Patients
Not yet reported Bristol-Myers Squibb 24 participants Est. completion 2015-07 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02458339
Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors
Not yet reported The University of Texas Health Science Center, Houston 7 participants Est. completion 2019-03-01 1 site Stand-aloneOther conditions: Brain Tumor, Recurrent, Malignant Neoplasm of Fourth Ventricle of BrainView official trial listing → -
Terminated NCT NCT02461784
The Effect of Methotrexate on Sperm Quality in Men With Inflammatory Bowel Disease
University of Wisconsin, Madison 30 participants Est. completion 2020-03-10 1 siteOther conditions: Inflammatory Bowel Disease (IBD)View official trial listing → -
Status unknown NCT NCT02466581
Dose Reduction for Early Rheumatoid Arthritis Patients With Low Disease Activity
Not yet reported Karolinska Institutet 25 participants Est. completion 2023-12 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02467504
Low-dose Recombinant Human IL-2 for the Treatment of Rheumatoid Arthritis
Not yet reported Peking University People's Hospital 47 participants Est. completion 2017-08-31 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02476084
Biomarker Signature and Musculoskeletal Ultrasound Profile in Rheumatoid Arthritis Patients
University of Oxford 43 participants Est. completion 2021-10-01 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02478424
Extended Use of Cannabidiol for the Prevention of Graft-versus-host-disease
Not yet reported Rabin Medical Center 10 participants Est. completion 2017-06 Stand-aloneOther conditions: Graft vs Host DiseaseView official trial listing → -
Completed NCT NCT02480153
A Study Of PF-06410293 (Adalimumab-Pfizer) And Adalimumab (Humira®) In Combination With Methotrexate In Subjects With Active Rheumatoid Arthritis (REFLECTIONS B538-02).
Not yet reported Pfizer 597 participants Est. completion 2017-12-06 183 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02480946
Safety and Tolerability Study of MBS2320 in Healthy Subjects and Subjects With Rheumatoid Arthritis
Not yet reported Modern Biosciences Ltd 105 participants Est. completion 2017-03 3 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT02481310
Combination Chemotherapy, Rituximab, and Ixazomib Citrate in Treating Patients With Non-Hodgkin Lymphoma
Not yet reported, Not yet reported Northwestern University 38 participants Est. completion 2024-07 5 sites Stand-aloneOther conditions: Adult Burkitt Lymphoma, B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Burkitt Lymphoma, Diffuse Large B-Cell Lymphoma, MYC Gene Mutation, Plasmablastic LymphomaView official trial listing → -
Completed NCT NCT02487069
Allo-HSCT With Alternative Donor in Treatment of Hematologic Malignancy
Not yet reported Nanfang Hospital, Southern Medical University 876 participants Est. completion 2020-02-29 1 site Stand-aloneOther conditions: Acute Leukemia, Chronic Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT02494882
Adding Ruxolitinib to a Combination of Dasatinib Plus Dexamethasone in Remission Induction Therapy in Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Patients Aged 40 Years or Older
Not yet reported Memorial Sloan Kettering Cancer Center 12 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02504268
Effects of Abatacept in Patients With Early Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 994 participants Est. completion 2020-03-19 201 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02504359
Combination Chemotherapy and Donor Stem Cell Transplant Followed by Ixazomib Citrate Maintenance Therapy in Treating Patients With Relapsed High-Risk Multiple Myeloma
Not yet reported OHSU Knight Cancer Institute 11 participants Est. completion 2020-09-09 2 sites Stand-aloneOther conditions: Plasma Cell Leukemia, Recurrent Plasma Cell MyelomaView official trial listing → -
Completed NCT NCT02504671
Study to Evaluate the Efficacy and Safety of GSK3196165 Plus Methotrexate in Subjects With Active Moderate-Severe Rheumatoid Arthritis
Not yet reported GlaxoSmithKline 222 participants Est. completion 2017-12-29 64 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT02506231
The Effect of Folinic Acid Rescue Following MTX GVHD Prophylaxis on Regimen Related Toxicity and Transplantation Outcome
Not yet reported, Not yet reported Rabin Medical Center 160 participantsOther conditions: Graft vs Host Disease, Allogeneic Hematopoietic Cell Transplantation, MucositisView official trial listing → -
Completed NCT NCT02517918
Metronomic Chemotherapy in Patients With Advanced Solid Tumor With Bone Metastasis and Advanced Pretreated Osteosarcoma
Not yet reported Institut Bergonié 23 participants Est. completion 2021-11-16 3 sites Stand-aloneObstructive sleep apnea Other conditions: Solid TumorView official trial listing → -
Completed NCT NCT02523976
Dasatinib Combined With Chemotherapy in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 30 participants Est. completion 2021-12-31 1 site Stand-aloneOther conditions: Acute,Leukemia, LymphoidView official trial listing → -
Status unknown NCT NCT02525172
Immune Modulation Therapy for Pompe Disease
Not yet reported National Taiwan University Hospital 8 participants Est. completion 2020-07 1 site Stand-aloneOther conditions: Pompe DiseaseView official trial listing → -
Completed NCT NCT02528435
Understanding Methotrexate Induced Gastrointestinal Intolerance in Juvenile Idiopathic Arthritis and Childhood Leukemia
University of Aarhus 145 participants Est. completion 2017-09Other conditions: Juvenile Idiopathic Arthritis, ALLView official trial listing → -
Terminated NCT NCT02531633
Efficacy and Safety Study of Sirukumab in Patients With Giant Cell Arteritis
Not yet reported GlaxoSmithKline 161 participants Est. completion 2018-03-21 63 sites Stand-aloneOther conditions: Giant Cell ArteritisView official trial listing → -
Status unknown NCT NCT02531841
High-dose Chemotherapy and ASCT or Consolidating Conventional Chemotherapy in Primary CNS Lymphoma
Not yet reported University Hospital Freiburg 250 participants Est. completion 2019-12 2 sitesOther conditions: Diffuse Large B-cell-lymphomaView official trial listing → -
Terminated NCT NCT02535806
Four Drug Reinduction With Bortezomib for Relapsed or Refractory ALL or LL in Children and Young Adults
Not yet reported Children's Mercy Hospital Kansas City 2 participants Est. completion 2017-05-25 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic LymphomaView official trial listing → -
Terminated NCT NCT02543931
Curcuma Longa L in Rheumatoid Arthritis
Not yet reported University of Arizona 3 participants Est. completion 2017-09 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02551575
Efficacy and Safety of Traditional Chinese Medicine (TCM) Comprehensive Therapy in Patients With Rheumatoid Arthritis
Not yet reported, Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 468 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02551718
High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia
Not yet reported University of Washington 34 participants Est. completion 2021-05-13 1 site Stand-aloneOther conditions: Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Acute Leukemia of Ambiguous LineageView official trial listing → -
Completed NCT NCT02553018
Comparison of Compliance and Evolution of Functional Capacity of Patients With Rheumatoid Arthritis Treated by Methotrexate Either by Auto-injector or by Conventional Sub-cutaneous Syringe
Not yet reported Nordic Pharma SAS 278 participants Est. completion 2017-08 2 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Active, not recruiting NCT NCT02553460
Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I
Not yet reported, Not yet reported St. Jude Children's Research Hospital 50 participants Est. completion 2031-10 15 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02557100
Study to Assess Changes in the Immune Profile in Adults With Early Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 80 participants Est. completion 2019-03-28 28 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02569736
Characterization of the Effect of Tocilizumab in Vivo and in Vitro on T Follicular Helper Cells in Rheumatoid Arthritis Patients and Consequence on B Cells Maturation
Association Aquitaine de Recherche Clinique en Rhumatologie 60 participants Est. completion 2016-12 1 siteOther conditions: Arthritis, Rheumatoid, Tocilizumab, T-Lymphocytes, Helper-InducerView official trial listing → -
Completed NCT NCT02576067
Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study
Not yet reported Icahn School of Medicine at Mount Sinai 123 participants Est. completion 2019-03-29 3 sites Stand-aloneCardiovascular disease Other conditions: Vascular InflammationView official trial listing → -
Withdrawn NCT NCT02578511
Standard Maintenance POMP/D Plus Ixazomib Maintenance Therapy in Adult Patients With Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma or Mixed Phenotype Acute Leukemia in Complete Remission (CR)
Not yet reported Ehab L Atallah Est. completion 2018-02-13 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia in Complete Remission, Lymphoblastic Lymphoma in Complete Remission, Mixed Phenotype Acute Leukemia in Complete RemissionView official trial listing → -
Completed NCT NCT02586246
Long-term Treatment Study of CDP870 Self-injection in Patients With Active Rheumatoid Arthritis Who Are Participating in the Long-term Treatment Studies (Study 275-08-002 or Study 275-08-004) of CDP870
Not yet reported Astellas Pharma Inc 86 participants Est. completion 2013-05 15 sitesOther conditions: Active Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02590510
Different Dose of Methotrexate for the Treatment of Meningeal Carcinomatosis
Not yet reported Hui Bu 50 participants Stand-aloneOther conditions: Meningeal CarcinomatosisView official trial listing → -
Status unknown NCT NCT02591823
Hair Fall in Patients on Low Dose Methotrexate
Columbia Asia 80 participants Est. completion 2016-05 1 siteOther conditions: Alopecia, Rheumatoid Arthritis, Methotrexate Adverse ReactionView official trial listing → -
Completed NCT NCT02608112
Study to Describe Real World Drug Retention Rate of the Tocilizumab at One Year
Hoffmann-La Roche 291 participants Est. completion 2018-07-26 77 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02611037
Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesothelioma
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 34 participants Est. completion 2024-01-26 1 site Stand-aloneOther conditions: Malignant Pleural Mesothelioma, MesotheliomaView official trial listing → -
Status unknown NCT NCT02611492
A Phase III Randomized Trial of the Reduction of Chemotherapy in Philadelphia Chromosome-positive ALL of Young Adults
Not yet reported Assistance Publique - Hôpitaux de Paris 265 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: Philadelphia Chromosome Positive Adult Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02623426
Macular Edema Ranibizumab v. Intravitreal Anti-inflammatory Therapy Trial
Not yet reported JHSPH Center for Clinical Trials 194 participants Est. completion 2022-02-02 33 sitesOther conditions: Uveitis, Macular EdemaView official trial listing → -
Active, not recruiting NCT NCT02629159
A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Adults With Rheumatoid Arthritis Who Are on a Stable Dose of Methotrexate and Who Have an Inadequate Response to Methotrexate
Not yet reported AbbVie 1629 participants Est. completion 2027-09-30 370 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02631239
MESA Versus ESA in the Treatment of Early Stage NK/T-cell Lymphoma
Not yet reported Ruijin Hospital 256 participants Est. completion 2022-07-17 1 siteOther conditions: Extranodal NK/T-cell Lymphoma, Nasal TypeView official trial listing → -
Completed NCT NCT02634801
A Study of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque Psoriasis Naive to Systemic Treatment
Not yet reported Eli Lilly and Company 162 participants Est. completion 2017-11-14 21 sitesOther conditions: Plaque PsoriasisView official trial listing → -
Completed NCT NCT02638948
Efficacy and Safety Study of BMS-986142 in Patients With Moderate to Severe Rheumatoid Arthritis
Not yet reported Bristol-Myers Squibb 508 participants Est. completion 2018-05-03 104 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02639650
Study of Paclitaxel Plus Cisplatin as the First-line Chemotherapy in High Risk Gestational Trophoblastic Tumor
Not yet reported Weiguo Lv 214 participants Est. completion 2026-03-01 1 siteOther conditions: Gestational Trophoblastic NeoplasmsView official trial listing → -
Completed NCT NCT02641977
Longterm Followup of Patients With Rheumatoid Arthritis Treated With Methotrexate
Ruhr University of Bochum 271 participants Est. completion 2016-08 1 siteOther conditions: External Causes of Morbidity and MortalityView official trial listing → -
Status unknown NCT NCT02643589
Dose Study of Antithymocyteglobulin in Haploidentical Allogeneic Stem Cell Transplantation
Not yet reported Nanfang Hospital, Southern Medical University 200 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Hematopoietic Stem Cell TransplantationView official trial listing → -
Status unknown NCT NCT02643823
Human Umbilical Cord-Mesenchymal Stem Cells for Rheumatoid Arthritis
Not yet reported Shenzhen Hornetcorn Bio-technology Company, LTD 40 participants Est. completion 2017-06 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02644044
Intrathecal Methotrexate for Progressive Multiple Sclerosis: An Open Label Single Arm Study
Not yet reported Tel-Aviv Sourasky Medical Center 30 participants Est. completion 2018-01 Stand-aloneOther conditions: To Evaluate the Effect of Therapy With IT MTX on the Disease Course of Patients With Progressive MSView official trial listing → -
Completed NCT NCT02644499
Comparison of Combination Disease Modifying Antirheumatic Drugs With Methotrexate Therapy in Early Rheumatoid Arthritis
Not yet reported Jawaharlal Institute of Postgraduate Medical Education & Research 186 participants Est. completion 2017-09-15 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT02647762
CF101 Therapy Compared to Methotrexate Therapy for Active Rheumatoid Arthritis
Not yet reported Can-Fite BioPharma 244 participants Est. completion 2020-11-30 35 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02655705
Comparison Study of Psoriasis Severity Assessment Tools
Not yet reported Seoul National University Hospital 34 participants Est. completion 2016-03 1 siteOther conditions: PsoriasisView official trial listing → -
Status unknown NCT NCT02657460
Clinical Trial of Tumor Cell-derived Microparticles Packaging Chemotherapeutic Drugs to Treat Malignant Pleural Effusion
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 90 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Malignant Pleural EffusionView official trial listing → -
Completed NCT NCT02660684
Study to Assess the Safety and Efficacy of Tacrolimus (Prograf Capsule/Injection) and Methotrexate (MTX) Combination Therapy for Prevention of Graft Versus Host Disease (GVHD) in Patients Who Received Peripheral Hematopoietic Stem Cell Transplantation From a Sibling Donor
Not yet reported Astellas Pharma Korea, Inc. 39 participants Est. completion 2010-02 3 sites Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Status unknown NCT NCT02660762
Modified MRCUKALLⅫ/ECOGE2993 Regimen for ALL
Not yet reported Sun Yat-sen University 100 participants Est. completion 2019-01 1 site Stand-aloneOther conditions: Leukaemia,LymphoblasticView official trial listing → -
Completed NCT NCT02663622
Phase II Trial of Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft-Versus-Host Disease (GVHD) Following Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-002)
Not yet reported Oncoimmune, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 44 participants Est. completion 2021-05-18 4 sites Stand-aloneOther conditions: Graft Versus Host Disease, Hematopoietic Stem Cell Transplantation, LeukemiaView official trial listing → -
Completed NCT NCT02667132
Granulomatous Mastitis Current Approach and Treatment
Granulomatous Mastitis Working Group 400 participants Est. completion 2018-01-04 1 siteOther conditions: Granulomatous, MastitisView official trial listing → -
Terminated NCT NCT02676323
Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported St. Jude Children's Research Hospital 19 participants Est. completion 2018-04-09 7 sitesOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT02677181
Efficacy and Safety Study of ATG for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT
Not yet reported Chinese PLA General Hospital 100 participants Est. completion 2022-04 1 site Stand-aloneOther conditions: aGVHDView official trial listing → -
Completed NCT NCT02680314
Is More Than One Dose of Misoprostol Needed to Expedite Vaginal Delivery in a Patient With an Unripe Cervix?
Not yet reported Montefiore Medical Center 243 participants Est. completion 2021-06-16Other conditions: Labor; Forced or Induced, Affecting Fetus or NewbornView official trial listing → -
Status unknown NCT NCT02683564
BOW015 (Infliximab-EPIRUS) and Infliximab in Patients With Active Rheumatoid Arthritis: The UNIFORM Study
Not yet reported Epirus Biopharmaceuticals (Switzerland) GmbH 548 participantsOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT02684071
Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors
Not yet reported Nicklaus Children's Hospital f/k/a Miami Children's Hospital 3 participants Est. completion 2019-12-09 1 site Stand-aloneOther conditions: Recurrent Childhood Medulloblastoma, Recurrent Childhood Ependymoma, Childhood Atypical Teratoid/Rhabdoid Tumor, Embryonal Tumor With Abundant Neuropil and True Rosettes, Metastatic Malignant Neoplasm to the LeptomeningesView official trial listing → -
Completed NCT NCT02688140
Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia
Not yet reported Technische Universität Dresden 133 participants Est. completion 2025-01-20 8 sitesOther conditions: Acute Promyelocytic LeukemiaView official trial listing → -
Status unknown NCT NCT02690922
Low-dose Chemotherapy Combine With Tyrosine Kinase Inhibitor to Treat ph+ Acute Lymphoblastic Leukemia Patients
Not yet reported Tongji Hospital 40 participants Est. completion 2017-05 1 site Stand-aloneOther conditions: ph+ Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02693210
A Study to Evaluate the Efficacy and Safety of Mabthera Alone and in Combination With Either Cyclophosphamide or Methotrexate in Patients With Rheumatoid Arthritis
Not yet reported Hoffmann-La Roche 161 participants Est. completion 2004-08 33 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02698657
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ASP5094 Following Multiple Intravenous Doses in Subjects With Rheumatoid Arthritis on Methotrexate
Not yet reported Astellas Pharma Global Development, Inc. 30 participants Est. completion 2017-09-07 13 sitesOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT02699710
Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy Subjects
Not yet reported Genentech, Inc. 50 participants Est. completion 2016-05-26 1 site Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Terminated NCT NCT02701517
Cyclosporine Plus Methotrexate or Alemtuzumab
Not yet reported Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea 72 participants Est. completion 2009-11 5 sitesOther conditions: Unrecognized Condition: Mature B or T-cell NeoplasmView official trial listing → -
Completed NCT NCT02706873
A Study to Compare Upadacitinib (ABT-494) Monotherapy to Methotrexate (MTX) Monotherapy in Adults With Rheumatoid Arthritis (RA) Who Have Not Previously Taken Methotrexate
Not yet reported AbbVie 1002 participants Est. completion 2022-11-10 290 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02706951
A Study Comparing Upadacitinib (ABT-494) Monotherapy to Methotrexate (MTX) Monotherapy in Adults With Rheumatoid Arthritis (RA) Who Have an Inadequate Response to MTX (SELECT-MONOTHERAPY)
Not yet reported AbbVie 648 participants Est. completion 2022-08-10 153 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02710734
Risk Enabled Therapy After Initiating Neoadjuvant Chemotherapy for Bladder Cancer (RETAIN)
Not yet reported Fox Chase Cancer Center 78 participants Est. completion 2025-12 4 sites Stand-aloneOther conditions: Urothelial Carcinoma of the BladderView official trial listing → -
Completed NCT NCT02714998
The Impact of Salpingectomy and Single Dose Systemic Methotrexate Treatments on Ovarian Reserve in Ectopic Pregnancy
Not yet reported Ege University 131 participants Est. completion 2015-02 1 siteOther conditions: Ectopic Pregnancy, InfertilityView official trial listing → -
Completed NCT NCT02715908
A Study to Evaluate the Long-term Safety and Efficacy of LBEC0101 in Subjects With Active RA Despite Methotrexate (MTX)
Not yet reported LG Life Sciences 148 participants Est. completion 2018-04 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02715947
Pharmacogenomics Study on Treatment of Psoriasis Vulgaris by Methotrexate
Not yet reported Central South University 400 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: Psoriasis VulgarisView official trial listing → -
Terminated NCT NCT02720120
A Study of Ocrelizumab in Participants With Moderate to Severe Rheumatoid Arthritis (RA)
Not yet reported, Not yet reported Hoffmann-La Roche 175 participants Est. completion 2013-02 49 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02722694
A Phase 3 Study of Abatacept in Chinese Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate
Not yet reported Jiangsu Simcere Pharmaceutical Co., Ltd. 360 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT02723994
A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia
Not yet reported Incyte Corporation 171 participants Est. completion 2026-03-03 111 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Withdrawn NCT NCT02724904
Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplant (HSCT) For Lymphoma
Not yet reported, Not yet reported Massachusetts General Hospital Est. completion 2021-12 2 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT02744196
Clinical Trial to Evaluate Efficacy and Safety of Acellbia® (JSC "BIOCAD") With Methotrexate in First Line Biological Therapy of Patients With Active Rheumatoid Arthritis
Not yet reported Biocad 159 participants Est. completion 2017-08 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02746380
A Study Comparing LBAL to Humira® in Subjects With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Not yet reported LG Life Sciences 383 participants Est. completion 2018-02-23 2 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT02748785
MTX Discontinuation and Vaccine Response
Not yet reported Seoul National University Hospital 277 participants Est. completion 2016-08 1 site Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Terminated NCT NCT02755194
"Drugs in Lactation" Analysis Consortium
The Hospital for Sick Children 68 participants Est. completion 2019-09-25 1 siteOther conditions: LactationView official trial listing → -
Completed NCT NCT02760368
Evaluation of the Effectiveness and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo, in Subjects With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Have Active Disease
Not yet reported R-Pharm International, LLC 428 participants Est. completion 2018-10 40 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02760407
Evaluation of the Efficacy and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo and Adalimumab, in Subjects With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Have Active Disease
Not yet reported R-Pharm International, LLC 1648 participants Est. completion 2019-11-05 203 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02760433
Evaluation of the Efficacy and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo, in Subjects With Rheumatoid Arthritis (RA) Who Were Taking an Existing Medication Called a Tumour Necrosis Factor Alpha Inhibitor But Had Active Disease
Not yet reported R-Pharm International, LLC 368 participants Est. completion 2019-10-01 116 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02762838
Comparative Clinical Trial of Efficacy and Safety of BCD-055 and Remicade® in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis
Not yet reported Biocad 426 participants Est. completion 2018-07 39 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02764281
MEDA Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation for Stage IV Natural Killer/T-cell Lymphoma
Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 53 participants Est. completion 2020-02 7 sites Stand-aloneOther conditions: Extranodal NK-T-Cell Lymphoma, Nasal TypeView official trial listing → -
Completed NCT NCT02764762
Triple Combination Therapy in High Risk Crohn's Disease (CD)
Not yet reported Takeda 55 participants Est. completion 2022-07-05 32 sites Stand-aloneOther conditions: Crohn DiseaseView official trial listing → -
Completed NCT NCT02766465
Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)
Not yet reported Medical College of Wisconsin 138 participants Est. completion 2023-08-02 35 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT02772965
Low Dose Oral Methotrexate in Pediatric Crohn's Disease Patients Initiating Anti-Tumor Necrosis Factor (Anti-TNF) Therapy
Not yet reported University of North Carolina, Chapel Hill 306 participants Est. completion 2022-04-07 32 sites Stand-aloneOther conditions: Pediatric Crohn's DiseaseView official trial listing → -
Status unknown NCT NCT02776605
Ponatinib With Chemotherapy for Young Adults Ph Positive Acute Lymphoblastic Leukemia
Not yet reported PETHEMA Foundation 30 participants Est. completion 2023-08 10 sites Stand-aloneOther conditions: ALLView official trial listing → -
Status unknown NCT NCT02777736
CNS Prophylaxis in Diffuse Large B-cell Lymphoma
Not yet reported Czech Lymphoma Study Group 500 participants Est. completion 2019-12 6 sites Stand-aloneOther conditions: Diffuse Large B-cell LymphomaView official trial listing → -
Status unknown NCT NCT02779114
RETRO (REduction of Therapy in RA Patients in Ongoing Remission)
Not yet reported University of Erlangen-Nürnberg Medical School 318 participants Est. completion 2018-06 12 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02779283
Personalized Kinase Inhibitor Therapy Combined With Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia
Not yet reported OHSU Knight Cancer Institute 7 participants Est. completion 2018-09-20 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02784106
Safety and Efficacy Study of M2951 in Participants With Rheumatoid Arthritis
Not yet reported EMD Serono Research & Development Institute, Inc. 65 participants Est. completion 2017-11-14 2 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02786134
Coronary Flow Reserve to Assess Cardiovascular Inflammation (CIRT-CFR)
Not yet reported Brigham and Women's Hospital 50 participants Est. completion 2019-10 1 site Stand-aloneMetabolic syndrome Other conditions: Coronary Heart Disease, Diabetes MellitusView official trial listing → -
Withdrawn NCT NCT02786563
Changes in Ultrasonographic Assessment of Inflammation Upon Initiation of Adalimumab Combination Therapy in Chinese Rheumatoid Arthritis (RA) Patients With Inadequate Response to Methotrexate
AbbVie Est. completion 2018-11-21 4 sitesOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT02788201
Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma
Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2019-10-23 1 site Stand-aloneOther conditions: Urothelial Carcinoma, Bladder Cancer, Urinary Bladder NeoplasmsView official trial listing → -
Withdrawn NCT NCT02795299
Study Evaluating Gerilimzumab´s Safety/Efficacy for Patients MTX or TNFα Antagonist Failed in Rheumatoid Arthritis
Not yet reported Bird Rock Bio, Inc. Est. completion 2019-09Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02799472
Mechanistic Study of GSK3196165 Plus Methotrexate (MTX) in Subjects With Active Rheumatoid Arthritis
Not yet reported GlaxoSmithKline 39 participants Est. completion 2017-10-30 16 sitesOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT02799888
Maraviroc-Based GVHD Prophylaxis in HLA-Unrelated and HLA-Mismatched Related Transplantation
Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 40 participants Est. completion 2017-04 1 site Stand-aloneOther conditions: Graft-versus-host Disease, Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT02814175
A Study of Subjects With Psoriatic Arthritis to Investigate the Effectiveness of Adalimumab Introduction Compared With Methotrexate Dose Escalation (CONTROL)
Not yet reported AbbVie 246 participants Est. completion 2020-03-19 60 sites Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT02818725
I-MVAC +/- Panitumumab as First-line Treatment of Advanced Urothelial Carcinoma Without H-Ras Nor K-Ras Mutations
Not yet reported UNICANCER 133 participants Est. completion 2017-09 17 sites Stand-aloneOther conditions: Infiltrating Urothelial Carcinoma, KRAS Gene MutationView official trial listing → -
Completed NCT NCT02825147
Pegaspargase and Methotrexate Based Regimens for Newly Diagnosed Extranodal NK/T Cell Lymphoma
Not yet reported Ruijin Hospital 40 participants Est. completion 2017-07 1 site Stand-aloneOther conditions: Nasal Type Extranodal NK/T-Cell LymphomaView official trial listing → -
Completed NCT NCT02828358
Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement
Not yet reported National Cancer Institute (NCI) 78 participants Est. completion 2024-12-31 170 sites Stand-aloneOther conditions: Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia, Mixed Phenotype Acute LeukemiaView official trial listing → -
Terminated NCT NCT02829424
Multicenter Randomized Double Blind Controlled-study to Assess the Potential of Methotrexate Versus Placebo to Improve and Maintain Response to Anti TNF- Alpha Agents in Adult Patients With Moderate to Severe Psoriasis
Not yet reported Assistance Publique Hopitaux De Marseille 78 participants Est. completion 2024-02-10 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT02831855
Methotrexate Withdrawal Study of Tofacitinib Modified Release Formulation in Subjects With Rheumatoid Arthritis
Not yet reported Pfizer 694 participants Est. completion 2018-12-17 136 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02833350
Safety and Efficacy Study of GDC-0853 Compared With Placebo and Adalimumab in Participants With Rheumatoid Arthritis (RA)
Not yet reported Genentech, Inc. 578 participants Est. completion 2018-07-02 150 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02842931
R-Dose-adjusted (DA) - EPOCH-21 Versus R-modified Non-Hodgkin Lymphoma (NHL)-Berlin-Frankfurt-Munster (BFM)-90 Program (mNHL-BFM-90) and Autologous Stem Cells Transplantation (Auto-SCT) in DLBCL With Poor Prognosis
Not yet reported National Research Center for Hematology, Russia 300 participants Est. completion 2023-02 1 siteOther conditions: Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT02845232
Economic Analysis of Blood Product Transfusions According to the Treatment of Acute Myeloid Leukaemia in the Elderly
Hospices Civils de Lyon 214 participants Est. completion 2015-05 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02845596
Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia
Not yet reported Michael Pulsipher 40 participants Est. completion 2023-07-19 13 sitesOther conditions: Severe Aplastic AnemiaView official trial listing → -
Active, not recruiting NCT NCT02845882
LBL-2016 for Children or Adolescents in China
Not yet reported Children's Cancer Group, China 150 participants Est. completion 2031-12 2 sitesOther conditions: Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT02852694
Reduce Risk for Crohn's Disease Patients
Not yet reported PIBD-Net 192 participants Est. completion 2021-06-14 1 siteOther conditions: Crohn's DiseaseView official trial listing → -
Terminated NCT NCT02862574
Andecaliximab as Add-On Therapy to a Tumor Necrosis Factor Inhibitor and Methotrexate Regimen in Adults With Moderately to Severely Active Rheumatoid Arthritis
Not yet reported Gilead Sciences 15 participants Est. completion 2017-08-07 8 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02867306
A Study to Evaluate the Pharmacokinetics of ASP1707 and Methotrexate in Patients With Rheumatoid Arthritis
Not yet reported Astellas Pharma Global Development, Inc. 10 participants Est. completion 2016-08-30 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02873936
Filgotinib Versus Placebo in Adults With Active Rheumatoid Arthritis (RA) Who Have an Inadequate Response to Biologic Disease-modifying Anti-rheumatic Drug(s) (DMARDs) Treatment
Not yet reported Gilead Sciences 449 participants Est. completion 2018-06-26 104 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02874092
Ticagrelor in Methotrexate-Resistant Rheumatoid Arthritis
Not yet reported NYU Langone Health 9 participants Est. completion 2019-06-19 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT02875314
HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors
Not yet reported Parth Patel 250 participants Est. completion 2030-12 62 sites Stand-aloneOther conditions: Medulloblastoma, Central Nervous System Embryonal TumorsView official trial listing → -
Status unknown NCT NCT02878161
Predictability Studies on the Efficacy of TNF-α Inhibitors in Chinese RA From "Real World"
Not yet reported Fen Li 240 participants Est. completion 2019-12 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02879643
Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 29 participants Est. completion 2024-12-31 35 sites Stand-aloneOther conditions: ALL, Childhood, Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Leukemia, AcuteView official trial listing → -
Completed NCT NCT02881086
Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment
Not yet reported Goethe University 1023 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic LymphomaView official trial listing → -
Terminated NCT NCT02882087
A Study of the Efficacy and Safety of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Inadequate Response to TNF-α Antagonists Due to Treat Moderate and Severe Rheumatoid Arthritis
Not yet reported RemeGen Co., Ltd. 60 participants Est. completion 2019-02-25 1 siteOther conditions: Moderate and Severe Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02883049
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations
Not yet reported National Cancer Institute (NCI) 5949 participants Est. completion 2026-03-31 239 sites Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, BCR-ABL1-Like, Central Nervous System Leukemia, Testicular LeukemiaView official trial listing → -
Completed NCT NCT02885181
Safety, Tolerability, and Efficacy of GS-9876 in Participants With Active Rheumatoid Arthritis on Background Therapy With Methotrexate
Not yet reported Gilead Sciences 83 participants Est. completion 2017-09-20 19 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02885597
Juanbi Pill for Rheumatoid Arthritis
Not yet reported, Not yet reported Cui xuejun 120 participants Est. completion 2020-12 1 site Stand-aloneOther conditions: Juanbi Pill, Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02885610
Study of RC18 Administered Subcutaneously to Subjects With Systemic Lupus Erythematosus(SLE)
Not yet reported RemeGen Co., Ltd. 249 participants Est. completion 2019-07-09 1 site Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Completed NCT NCT02886728
Filgotinib Alone and in Combination With Methotrexate (MTX) in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Are Naive to MTX Therapy
Not yet reported Gilead Sciences 1252 participants Est. completion 2019-05-08 186 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02889796
Filgotinib in Combination With Methotrexate in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate
Not yet reported Gilead Sciences 1759 participants Est. completion 2019-06-20 230 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02894645
Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study
Not yet reported National University Hospital, Singapore 500 participants 4 sitesOther conditions: Acute Lymphoblastic Leukemia (ALL)View official trial listing → -
Status unknown NCT NCT02897011
2-week dc of MTX and Influenza Vaccination in RA
Not yet reported Seoul National University Hospital 318 participants Est. completion 2017-08 3 sites Stand-aloneOther conditions: Rheumatoid Arthritis, Influenza, MethotrexateView official trial listing → -
Completed NCT NCT02897817
Treatment Adherence to Injectable Methotrexate in Rheumatoid Arthritis
Nordic Pharma SAS 471 participants Est. completion 2017-12 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02902861
Trial in Patients With Psoriasis Treated With Methotrexate Using an Optimized Treatment Schedule (METOP)
Not yet reported Prof. Kristian Reich 120 participants Est. completion 2015-05 1 siteOther conditions: Psoriasis VulgarisView official trial listing → -
Completed NCT NCT02905110
Methotrexate and Etoposide Infusions Into the Fourth Ventricle in Children with Recurrent Posterior Fossa Brain Tumors
Not yet reported The University of Texas Health Science Center, Houston 3 participants Est. completion 2022-03-04 1 site Stand-aloneOther conditions: Brain Tumor RecurrentView official trial listing → -
Completed NCT NCT02912676
Thiopurine EnhAnced Maintenance Therapy
Not yet reported, Not yet reported Kjeld Schmiegelow 30 participants Est. completion 2020-04 4 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT02913261
Safety and Efficacy of Ruxolitinib Versus Best Available Therapy in Patients With Corticosteroid-refractory Acute Graft vs. Host Disease After Allogeneic Stem Cell Transplantation
Not yet reported Novartis Pharmaceuticals 310 participants Est. completion 2021-04-23 103 sitesOther conditions: Corticosteroid Refractory Acute Graft vs Host DiseaseView official trial listing → -
Completed NCT NCT02916979
Myeloid-Derived Suppressor Cells and Checkpoint Immune Regulators' Expression in Allogeneic SCT Using FluBuATG
Not yet reported Dartmouth-Hitchcock Medical Center 20 participants Est. completion 2022-02-11 1 siteOther conditions: Leukemia, Lymphoid, Leukemia, Myeloid, Myelodysplastic Syndromes, Myelofibrosis, Lymphoma, Malignant, Multiple Myeloma, Waldenstrom MacroglobulinemiaView official trial listing → -
Completed NCT NCT02926560
Study Medication Adherence and Its Determinants in Chronic Disease Through the Example of Methotrexate in Chronic Inflammatory Rheumatism
Centre Hospitalier Universitaire de Nīmes 137 participants Est. completion 2018-05-30 1 siteOther conditions: Rheumatic DiseasesView official trial listing → -
Terminated NCT NCT02930343
Comparison of Disease Modifying Antirheumatic Drugs Therapy in Patients With RA Failing Methotrexate Monotherapy
Not yet reported Jawaharlal Institute of Postgraduate Medical Education & Research 136 participants Est. completion 2018-08 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02934204
Temozolomide in Treatment of Patients With Primary Central Nervous System Lymphoma
Not yet reported Guangdong Provincial People's Hospital 51 participants Est. completion 2019-02 1 site Stand-aloneOther conditions: Primary CNS LymphomaView official trial listing → -
Terminated NCT NCT02935387
REMission INDuction in Very Early Rheumatoid Arthritis
Not yet reported UMC Utrecht 53 participants Est. completion 2019-01-09 2 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT02940561
BE Study in Patients - Methotrexate Tablets
Not yet reported Amneal Pharmaceuticals, LLC 48 participants Est. completion 2016-10 3 sites Stand-aloneOther conditions: Psoriasis, Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02960438
A Dose Response Study of E6011 in Participants With Rheumatoid Arthritis Inadequately Responding to Methotrexate
Not yet reported Eisai Co., Ltd. 273 participants Est. completion 2019-09-17 90 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02969044
Study To Assess The Efficacy And Safety Of Pf-06651600 In Subjects With Rheumatoid Arthritis With An Inadequate Response To Methotrexate
Not yet reported Pfizer 70 participants Est. completion 2017-12-12 30 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02969083
Feasibility of Neo-adjuvant Versus Adjuvant Chemotherapy in Upper Tract Urothelial Carcinoma
Not yet reported The European Uro-Oncology Group 200 participants Est. completion 2025-12 29 sitesOther conditions: Upper Tract Urothelial CarcinomaView official trial listing → -
Active, not recruiting NCT NCT02981628
Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 80 participants Est. completion 2026-12-31 157 sites Stand-aloneOther conditions: Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma, Refractory B Acute Lymphoblastic Leukemia, Refractory B Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT02983227
A Study to Evaluate the Long-Term Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Rheumatoid Arthritis Enrolled in Study GA29350
Not yet reported Genentech, Inc. 496 participants Est. completion 2019-07-17 104 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02983942
Ketogenic Diet Adjunctive to HD-MTX Chemotherapy for Primary Central Nervous System Lymphoma
Not yet reported, Not yet reported Beijing Tiantan Hospital 50 participants Est. completion 2019-12 1 siteOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT02986503
European Study in Bone Sarcoma Patients Over 40 Years
Italian Sarcoma Group 100 participants Est. completion 2016-11 3 sitesObstructive sleep apnea Other conditions: Spindle Cell Sarcoma of BoneView official trial listing → -
Completed NCT NCT02996500
Safety and Efficacy of Pf-06650833 In Subjects With Rheumatoid Arthritis, With An Inadequate Response To Methotrexate
Not yet reported Pfizer 269 participants Est. completion 2018-08-15 103 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT02996617
PEG-rhG-CSF in Patients With Non-Hodgkin Lymphoma Receiving Chemotherapy to Prevent Neutropenia
Not yet reported Shandong Provincial Hospital 240 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: Lymphoma,Non-HodgkinView official trial listing → -
Terminated NCT NCT03001219
A Study of RO7123520 to Evaluate the Safety and Efficacy in Participants With Moderately To Severely Active Rheumatoid Arthritis (RA) Who Are Inadequately Responding to Anti-Tumor Necrosis Factor (TNF)-Alpha Therapy
Not yet reported Hoffmann-La Roche 109 participants Est. completion 2018-11-06 81 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03006991
Study of Methotrexate Given to Juvenile Idiopathic Arthritis Patients Based on Pharmacogenomics and Pharmacometrics
Guangzhou Women and Children's Medical Center 100 participants Est. completion 2023-12 1 siteOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Active, not recruiting NCT NCT03007147
Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Not yet reported Children's Oncology Group 352 participants Est. completion 2034-09-30 226 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia, T Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT03011281
Effectiveness and Safety of Tofacitinib in Korean Patients With Rheumatoid Arthritis
Hanyang University 378 participants Est. completion 2021-12 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03016013
A Study of the Efficacy and Safety of TACI-antibody Fusion Protein Injection (RC18) in Subjects with Inadequate Response to MTX Due to Treat Moderate and Severe Rheumatoid Arthritis.
Not yet reported RemeGen Co., Ltd. 479 participants Est. completion 2022-12-29 1 siteOther conditions: Moderate and Severe RheumatoId ArthritisView official trial listing → -
Terminated NCT NCT03016260
RABIOPRED - a Validation Study of Theranostic Test to PREDict Treatment Response of Anti-TNFα BIologicals in Rheumatoid Arthritis
TcLand Expression S.A. 250 participants Est. completion 2019-12-20 8 sitesOther conditions: RheumatoId ArthritisView official trial listing → -
Active, not recruiting NCT NCT03020030
Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents
Not yet reported Dana-Farber Cancer Institute 560 participants Est. completion 2034-11 9 sitesOther conditions: Acute Lymphoblastic Leukemia, PediatricView official trial listing → -
Status unknown NCT NCT03022747
Optimizing 6-mercaptopurine Therapy in Pediatric Acute Lymphoblastic Leukemia by Using Allopurinol
Not yet reported Vastra Gotaland Region 60 participants Est. completion 2019-04 3 sites Stand-aloneOther conditions: Lymphoblastic Leukemia, Acute, ChildhoodView official trial listing → -
Completed NCT NCT03028467
Evaluation of Pharmacokinetics and Safety of GSK3196165 in Combination With Methotrexate in Japanese Subjects With Rheumatoid Arthritis
Not yet reported, Not yet reported GlaxoSmithKline 15 participants Est. completion 2017-12-20 32 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT03056924
Immunogenicity of Influenza, Pneumococcal and Hepatitis B Vaccines in IBD Patients Treated With Vedolizumab
Boston Medical Center 173 participants Est. completion 2019-01-15 1 siteOther conditions: Inflammatory Bowel DiseasesView official trial listing → -
Completed NCT NCT03058471
Efficacy of Starting Methotrexate Early in Chikungunya Arthritis
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 60 participants Est. completion 2018-05 1 siteOther conditions: Early Chikungunya ArthritisView official trial listing → -
Completed NCT NCT03058900
Efficacy and Safety of Fecal Microbiota Transplantation in Peripheral Psoriatic Arthritis
Not yet reported Odense University Hospital 31 participants Est. completion 2020-06-02 2 sites Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Status unknown NCT NCT03063983
Clinical Trial Evaluating Metronomic Chemotherapy in Patients With Metastatic Osteosarcoma
Not yet reported Grupo de Apoio ao Adolescente e a Crianca com Cancer 158 participants Est. completion 2022-01-31 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Withdrawn NCT NCT03066466
Randomized Study: Standard of Care With or Without Atorvastatin for Prevention of GVHD for Matched Unrelated Donor BMT
Not yet reported Loyola University Est. completion 2021-02-28 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT03071276
Selinexor in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 37 participants Est. completion 2019-04-30 7 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Status unknown NCT NCT03088059
Biomarker-based Study in R/M SCCHN
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 340 participants Est. completion 2025-12 36 sites Stand-aloneOther conditions: Carcinoma, Squamous Cell of Head and NeckView official trial listing → -
Completed NCT NCT03096275
Comparison of Mycophenolate Mofetil and Cyclophosphamide for Active Takayasu's Arteritis
Not yet reported Chinese SLE Treatment And Research Group 138 participants Est. completion 2022-11-11 7 sites Stand-aloneOther conditions: Takayasu ArteritisView official trial listing → -
Completed NCT NCT03103334
A Bioavailability Study of Methotrexate 25 mg Administered by Needle Injection and a Pre Filled Needle-free Device in Healthy Volunteers.
Not yet reported Crossject 58 participants Est. completion 2014-12 Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03107299
Evaluation of the Impact of 3 Methods of Communication on the Adherence of Methotrexate in Patients With Rheumatoid Arthritis
Not yet reported Centre Hospitalier Universitaire, Amiens 98 participants Est. completion 2019-04-05 1 siteOther conditions: Methotrexate, Polyarthritis; RheumatoidView official trial listing → -
Completed NCT NCT03112603
A Study of Ruxolitinib vs Best Available Therapy (BAT) in Patients With Steroid-refractory Chronic Graft vs. Host Disease (GvHD) After Bone Marrow Transplantation (REACH3)
Not yet reported Incyte Corporation 330 participants Est. completion 2022-12-15 191 sitesOther conditions: Graft-versus-host Disease (GVHD)View official trial listing → -
Active, not recruiting NCT NCT03117751
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma
Not yet reported, Not yet reported St. Jude Children's Research Hospital 790 participants Est. completion 2028-09-30 8 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT03120949
Efficacy and Safety of Olokizumab in Subjects With Moderately to Severely Active Rheumatoid Arthritis
Not yet reported R-Pharm International, LLC 2106 participants Est. completion 2021-09-01 239 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT03121014
Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes
Not yet reported University of Illinois at Chicago 38 participants Est. completion 2026-04 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT03123718
High-dose Intravenous Methotrexate Versus Intrathecal Methotrexate for Central Nervous System Prophylaxis in DLBCL
Not yet reported Chonnam National University Hospital 205 participants Est. completion 2021-06-30 1 siteOther conditions: DLBCLView official trial listing → -
Completed NCT NCT03123887
Evaluate the Hematological Remission Rates and Survival Among Chinese Adult Patients With B-precursor ALL
Harbin Hematology and Oncology Institute 632 participants Est. completion 2016-10-10 1 siteOther conditions: B-precursor Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT03131973
Effects of Concomitant Administration of BMS-986195 on Methotrexate, Caffeine, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin
Not yet reported Bristol-Myers Squibb 26 participants Est. completion 2017-11-10 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03138694
Adnexal Mass After Methotrexate Treatment for Ectopic Pregnancies
Tel-Aviv Sourasky Medical Center 500 participants Est. completion 2019-10Other conditions: Ectopic PregnanciesView official trial listing → -
Completed NCT NCT03139136
Safety, Tolerability and Efficacy of MBS2320 in Patients With Rheumatoid Arthritis
Not yet reported Modern Biosciences Ltd 121 participants Est. completion 2019-08-13 3 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT03147612
Low-Intensity Chemotherapy, Ponatinib and Blinatumomab in Treating Patients With Philadelphia Chromosome-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center 22 participants Est. completion 2027-02-28 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia With BCR-ABL1, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Acute Lymphoblastic Leukemia, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT03148860
Impact of Concomitant MTX on Efficacy, Safety and Adherence of Ustekinumab-treatment in Patients With Active PsA
Not yet reported Dr. Frank Behrens 186 participants Est. completion 2021-10-21 1 siteOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT03155347
An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) Therapy
Not yet reported Hoffmann-La Roche 340 participants Est. completion 2022-08-08 20 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT03161457
A Study of JHL1101 Versus MabThera® in Subjects With Severe Rheumatoid Arthritis
Not yet reported JHL Biotech, Inc. 153 participants Est. completion 2019-04-16 32 sitesOther conditions: Rheumatoid Arthritis, Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT03163966
A Study of the EP4 Antagonist CR6086 in Combination With Methotrexate, in DMARD-naïve Patients With Early Rheumatoid Arthritis
Not yet reported Rottapharm Biotech 248 participants Est. completion 2019-01-08 1 site Stand-aloneOther conditions: Rheumatoid Arthritis, DMARD-naive and Early Disease PatientsView official trial listing → -
Active, not recruiting NCT NCT03164057
A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 206 participants Est. completion 2027-06 10 sitesOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT03171831
Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major
Not yet reported First Affiliated Hospital of Guangxi Medical University 30 participants Est. completion 2022-04-01 1 site Stand-aloneOther conditions: Thalassemia MajorView official trial listing → -
Completed NCT NCT03172325
Study to Demonstrate Non-Inferior Efficacy and Safety of CinnoRA® Versus Humira® for Treatment of Active RA
Not yet reported Cinnagen 136 participants Est. completion 2017-01-04 10 sites Stand-aloneOther conditions: Active Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03173040
The Efficacy of the Traditional Chinese Medicine Niubang Pill Combined With Methotrexate on Active Rheumatoid Arthritis
Not yet reported, Not yet reported Cui xuejun 100 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: Niu Bang Zi Pill, Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT03175978
IGF-MTX Conjugate in the Treatment of Myelodysplastic Syndrome
Not yet reported, Not yet reported IGF Oncology, LLC 2 participants Est. completion 2021-09-30 2 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, Leukemia, Myelomonocytic, Chronic, Anemia, Refractory, With Excess of BlastsView official trial listing → -
Terminated NCT NCT03193931
Study Comparing Pembrolizumab With Methotrexate in Elderly, Frail or Cisplatin-ineligible Patients With Head and Neck Cancers
Not yet reported AIO-Studien-gGmbH 47 participants Est. completion 2022-03-23 1 siteOther conditions: Cancer of Head and NeckView official trial listing → -
Completed NCT NCT03194204
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial
Not yet reported Assiut University 160 participants Est. completion 2020-02-20 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03194932
Study of Venetoclax in Combination With Chemotherapy in Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Leukemia of Ambiguous Lineage
Not yet reported St. Jude Children's Research Hospital 62 participants Est. completion 2022-06-22 3 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03198689
Brentuximab Vedotin in Early Diffuse Cutaneous Systemic Sclerosis
Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 11 participants Est. completion 2023-08-28 1 site Stand-aloneOther conditions: Diffuse Cutaneous Systemic SclerosisView official trial listing → -
Status unknown NCT NCT03204136
Tacrolimus Versus Methotrexate as Rescue Therapy for Refractory Inflammatory Bowel Disease
Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, China 60 participants Est. completion 2019-12-01 1 siteOther conditions: Inflammatory Bowel DiseasesView official trial listing → -
Active, not recruiting NCT NCT03206671
Treatment Protocol of the NHL-BFM and the NOPHO Study Groups for Mature Aggressive B-cell Lymphoma and Leukemia in Children and Adolescents
Not yet reported University Hospital Muenster 650 participants Est. completion 2027-06 88 sites Stand-aloneOther conditions: Mature B-cell Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT03217734
MAP Study: Methotrexate and Adalimumab in Psoriasis
Not yet reported, Not yet reported Jeffrey J Crowley MD 56 participants Est. completion 2018-12-31 4 sitesOther conditions: PsoriasisView official trial listing → -
Status unknown NCT NCT03218059
Outcome After MTX & Transvaginal Surgery or UAE & Uterine Curettage in Patients With Cesarean Scar Pregnancy
Not yet reported Shanghai First Maternity and Infant Hospital 100 participants Est. completion 2018-12 1 siteOther conditions: Cesarean Scar Pregnancy, MenstruationView official trial listing → -
Completed NCT NCT03219437
A Study Comparing the Safety and Efficacy of Risankizumab to Methotrexate in Subjects With Moderate to Severe Plaque Psoriasis
Not yet reported AbbVie 104 participants Est. completion 2021-11-26 11 sitesOther conditions: PsoriasisView official trial listing → -
Status unknown NCT NCT03230708
Clinical Study of Autologous Erythrocytes Derived MPs Packaging MTX Peritoneal Perfusion to Treat Malignant Ascites
Not yet reported, Not yet reported Hui ting Xu,MD 18 participants Est. completion 2018-02-01 1 siteOther conditions: Malignant AscitesView official trial listing → -
Completed NCT NCT03233230
Phase IIb Study of Evobrutinib in Subjects With Rheumatoid Arthritis
Not yet reported EMD Serono Research & Development Institute, Inc. 390 participants Est. completion 2019-09-23 97 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT03239600
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Proof of Mechanism of GSK2618960 in Primary Sjögren's Syndrome (pSS)
Not yet reported GlaxoSmithKline Est. completion 2017-10-12 1 site Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Completed NCT NCT03244462
Food Effect, Oral & Intravenous Pharmacokinetics and Absolute Bioavailability of BAY1834845 Including Drug-drug Interaction With Methotrexate
Not yet reported Bayer 10 participants Est. completion 2018-07-20 1 site Stand-aloneOther conditions: InflammationView official trial listing → -
Completed NCT NCT03246750
B-MAD Chemotherapy in Newly-diagnosed Extranodal NK/ T-cell Lymphoma
Not yet reported, Not yet reported The Thai Lymphoma Study Group 34 participants Est. completion 2024-04-10 1 site Stand-aloneOther conditions: Extranodal NK/T-cell LymphomaView official trial listing → -
Completed NCT NCT03254589
Methotrexate, Blood Pressure and Arterial Function in Rheumatoid Arthritis
Not yet reported Flinders University 124 participants Est. completion 2023-12-31 1 site Stand-aloneOther conditions: Rheumatoid Arthritis, Stiffness, Aortic, Endothelial Dysfunction, Cardiovascular Risk FactorView official trial listing → -
Completed NCT NCT03257852
A Study to Evaluate the Efficacy and Safety of ASP5094 in Patients With Rheumatoid Arthritis on Methotrexate
Not yet reported Astellas Pharma Inc 66 participants Est. completion 2018-10-16 31 sites Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT03275025
A Phase 2 Study to Evaluate the Safety and Efficacy of YRA-1909 in Patients With Rheumatoid Arthritis
Not yet reported Yungjin Pharm. Co., Ltd. 116 participants Est. completion 2019-11-19 14 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03277924
Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas
Not yet reported, Not yet reported Grupo Espanol de Investigacion en Sarcomas 197 participants Est. completion 2024-06-30 13 sites Stand-aloneOther conditions: Soft Tissue Sarcoma, Bone SarcomaView official trial listing → -
Status unknown NCT NCT03280979
Rescue Regimen and High Dose Methotrexate in Management of Presistent Gestational Trophoplastic Neoplasia
Not yet reported, Not yet reported Assiut University 170 participants Est. completion 2019-10Other conditions: Gestational Trophoblastic DiseaseView official trial listing → -
Active, not recruiting NCT NCT03286634
ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016
Not yet reported National Hospital Organization Nagoya Medical Center 60 participants Est. completion 2033-03-31 10 sites Stand-aloneOther conditions: Down Syndrome, Acute Lymphoblastic Leukemia, Childhood CancerView official trial listing → -
Status unknown NCT NCT03296306
Four Cycles Versus Six Cycles of Cisplatin-based Chemotherapy in Metastatic Urothelial Carcinoma
Not yet reported Asan Medical Center 330 participants Est. completion 2022-02 19 sites Stand-aloneOther conditions: Bladder Cancer, Ureter Cancer, Urethral Cancer, Transitional Cell CarcinomaView official trial listing → -
Terminated NCT NCT03320642
GRAVITAS-119: Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease
Not yet reported Incyte Corporation 84 participants Est. completion 2022-02-17 17 sites Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT03320928
Skin Disease and Pulmonary Mortality After Transplantation
Karolinska University Hospital 79 participants Est. completion 2016-11-24Other conditions: Pulmonary Mortality, Acute GVH DiseaseView official trial listing → -
Status unknown NCT NCT03321890
Chidamide Combined With PECM in Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)
Not yet reported Sun Yat-sen University 102 participants Est. completion 2020-12-31 1 site Stand-aloneOther conditions: Peripheral T-cell LymphomaView official trial listing → -
Status unknown NCT NCT03324412
Efficacy and Safety of TwHF and MTX in Patients With Rheumatoid Arthritis
Not yet reported, Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 216 participants Est. completion 2019-09-30 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03327116
Effect of Methotrexate on Inflammatory Response in Adult Atopic Dermatitis Patients
Not yet reported University of Sao Paulo General Hospital 10 participants Est. completion 2018-12-01 1 site Stand-aloneOther conditions: Atopic DermatitisView official trial listing → -
Completed NCT NCT03332719
Efficacy, Safety and Immunogenicity of Enerceptan Compared to Enbrel in Rheumatoid Arthritis
Not yet reported Gema Biotech S.A. 168 participants Est. completion 2017-09 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03337815
A Specification Clinical Application Research of Tripterygium Wilfordii Treating Rheumatoid Arthritis
Not yet reported, Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 264 participants Est. completion 2019-09-30 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03349281
Pevonedistat With VXLD Chemotherapy for Adolescent/Young Adults With Relapsed/Refractory ALL or Lymphoblastic NHL
Not yet reported Julio Barredo, MD 6 participants Est. completion 2022-10-12 1 site Stand-aloneOther conditions: Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT03352622
Pharmacogenomic in Colombian Patients With Rheumatoid Arthritis
Not yet reported Universidad de Antioquia 372 participants Est. completion 2020-09-17 1 siteOther conditions: Pharmacological ActionView official trial listing → -
Terminated NCT NCT03355482
MRI Evaluation Assessing Synovitis to Address the Unmet Need for Reliable Endpoints in SLE
Not yet reported Oklahoma Medical Research Foundation 9 participants Est. completion 2022-12-16 1 siteOther conditions: Systemic Lupus Erythematosus ArthritisView official trial listing → -
Status unknown NCT NCT03360760
Timing of Surgery in Nonmetastatic Osteosarcoma of the Pelvis and Sacrum
Not yet reported Peking University People's Hospital 100 participants Est. completion 2025-02 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Status unknown NCT NCT03369795
Add-on Methotrexate for the Treatment of Schizophrenia
Not yet reported Sheba Medical Center 100 participants Est. completion 2020-01-01 Stand-aloneOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT03371667
To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids
Not yet reported Assistance Publique - Hôpitaux de Paris 104 participants Est. completion 2025-01-24 1 site Stand-aloneOther conditions: Allogeneic Disease, GVH - Graft Versus Host Reaction, GVHD, Acute, Stem Cell Transplant ComplicationsView official trial listing → -
Status unknown NCT NCT03383406
A Phase II Trial of Ifosfamide, Etoposide, Cytarabine, and Methotrexate (IVAM) Chemotherapy for Refractory or Relapsed Diffuse Large B Cell Lymphoma
Not yet reported Asan Medical Center 30 participants Est. completion 2025-12-31 Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Completed NCT NCT03384654
A Study to Evaluate the Efficacy and Safety of Daratumumab in Pediatric and Young Adult Participants Greater Than or Equal to (>=)1 and Less Than or Equal to (<=) 30 Years of Age With Relapsed/Refractory Precursor B-cell or T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Not yet reported Janssen Research & Development, LLC 47 participants Est. completion 2022-09-27 53 sites Stand-aloneOther conditions: Precursor Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Status unknown NCT NCT03390387
Childhood Acute Lymphoblastic Leukemia Treatment Protocol Moscow-Berlin 2015 (ALL-MB 2015)
Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 4000 participants Est. completion 2025-11 58 sitesOther conditions: Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT03390946
Feasibility Study of Interval Compressed Regimen Using Four-drugs for Osteosarcoma
Not yet reported Byung-Kiu Park 23 participants Est. completion 2020-12-31 1 site Stand-aloneObstructive sleep apnea Other conditions: Feasibility, Treatment Response, BiomarkerView official trial listing → -
Completed NCT NCT03402087
A Study to Investigate BMS-986165 and Methotrexate in Healthy Male Patients
Not yet reported Bristol-Myers Squibb 30 participants Est. completion 2018-03-25 1 site Stand-aloneOther conditions: Lupus, Psoriatic ArthritisView official trial listing → -
Status unknown NCT NCT03403140
Long Term Efficacy, Safety and Immunogenicity of Enerceptan in Rheumatoid Arthritis ( GEMENE002 )
Not yet reported Gema Biotech S.A. 141 participants Est. completion 2018-10-31 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03408210
Total Marrow and Lymphoid Irradiation and Chemotherapy for Myelodysplastic Syndrome or Acute Leukemia
Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 191 participants Est. completion 2022-08 1 site Stand-aloneOther conditions: Myelodysplastic Syndromes, Acute LeukemiaView official trial listing → -
Status unknown NCT NCT03408223
Total Marrow and Lymphoid Irradiation and Chemotherapy for High-Risk Acute Leukemia
Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 100 participants Est. completion 2022-12 1 site Stand-aloneOther conditions: Acute LeukemiaView official trial listing → -
Status unknown NCT NCT03408756
Comparison of Oral Versus Subcutaneous Route of Methotrexate Administration in Moderate to Severe Psoriasis
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 100 participants Est. completion 2019-12-30Other conditions: Psoriasis VulgarisView official trial listing → -
Completed NCT NCT03411798
Sequential Application of Yisaipu® and DMARDs in Treating Mild-to-Moderate AS
Not yet reported Nanfang Hospital, Southern Medical University 76 participants Est. completion 2019-07-01 1 site Stand-aloneOther conditions: Ankylosing SpondylitisView official trial listing → -
Status unknown NCT NCT03424629
Safety and Efficacy of UC-MSCs in Patients With Plaque Psoriasis
Not yet reported Tianjin Ever Union Biotechnology Co., Ltd. 57 participants Est. completion 2019-12-31 2 sitesOther conditions: Moderate and Severe Plaque PsoriasisView official trial listing → -
Status unknown NCT NCT03440892
Effects of Antirheumatic Treatment on Levels of Survivin in Rheumatoid Arthritis Patients
Vastra Gotaland Region 2500 participants Est. completion 2025-01 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03445871
Association Between Methotrexate Erythrocyte Polyglutamate Concentration and Clinical Response in Rheumatoid Arthritis Patients Treated With Subcutaneous Injectable Methotrexate
Not yet reported Centre Hospitalier Universitaire de Saint Etienne 60 participants Est. completion 2020-05-28 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03449758
Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid Arthritis
Not yet reported Sanofi 84 participants Est. completion 2019-07-31 33 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT03456817
HIgh Dose Thymoglobulin Instead of Cyclosporine With a Low Dose of Thymoglobulin for GVHD Prophylaxis
Not yet reported AHS Cancer Control Alberta 68 participants Est. completion 2025-05-31 1 site Stand-aloneOther conditions: Graft-versus-host-disease, RelapseView official trial listing → -
Status unknown NCT NCT03465280
Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP)
Newcastle-upon-Tyne Hospitals NHS Trust 400 participants Est. completion 2022-08-31 48 sitesOther conditions: Recurrent Respiratory Papillomatosis, Human Papilloma VirusView official trial listing → -
Completed NCT NCT03472274
Durvalumab (MEDI4736) and TREmelimumab in NEOadjuvant Bladder Cancer Patients (DUTRENEO)
Not yet reported Fundacion CRIS de Investigación para Vencer el Cáncer 101 participants Est. completion 2023-04-12 11 sitesOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT03478111
CMAB008 With MTX Therapy in Adult Patients With Moderately to Severely Active Rheumatoid Arthritis
Not yet reported Shanghai Biomabs Pharmaceutical Co., Ltd. 390 participants Est. completion 2019-08-27 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03479918
R-BL-M-04 Versus R-(DA)-EPOCH and Autologous Stem Cells Transplantation in Patients With High-Grade B-cell Lymphoma Double-hit (HGBL DH) and High-Grade B-cell Lymphoma Not Otherwise Specified (HGBL NOS)
Not yet reported Elena N.Parovichnikova 80 participants Est. completion 2024-03-15 1 siteOther conditions: Lymphoma, High-GradeView official trial listing → -
Terminated NCT NCT03488225
Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2020-04-02 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia in Remission, B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeView official trial listing → -
Status unknown NCT NCT03488901
Chemoresistance of Trophoblastic Tumors
Hospices Civils de Lyon 72 participants Est. completion 2018-12 1 siteOther conditions: Trophoblastic TumorView official trial listing → -
Completed NCT NCT03492658
Abatacept to Silence Anti-citrullinated Protein Antibody-expressing B Cells in Rheumatoid Arthritis (ASCARA)
Not yet reported Leiden University Medical Center 46 participants Est. completion 2022-04-06 1 site Stand-aloneOther conditions: Rheumatoid Arthritis, Rheumatic DiseasesView official trial listing → -
Completed NCT NCT03495960
Study on Tailored Treatment in Elderly Patients With Newly Diagnosed Primary Lymphoma of Central Nervous System
Not yet reported International Extranodal Lymphoma Study Group (IELSG) 72 participants Est. completion 2024-12-12 34 sites Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT03505008
Evaluation of the Optimal MTX Dose as an Add-on Therapy to Adalimumab for RA Patients in Japan, South Korea and Taiwan
Not yet reported Keio University 300 participants Est. completion 2021-05-11 24 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT03515200
Treatment With Combination Chemotherapy for Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported St. Jude Children's Research Hospital 12 participants Est. completion 2020-07-29 1 siteOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia With Failed RemissionView official trial listing → -
Terminated NCT NCT03516903
Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After STEMI
Not yet reported, Not yet reported University of Sao Paulo 35 participants Est. completion 2020-12-17 1 siteCardiovascular disease Other conditions: Myocardial Remodeling, VentricularView official trial listing → -
Terminated NCT NCT03518112
Low-Intensity Chemotherapy and Blinatumomab in Treating Patients With Philadelphia Chromosome Negative Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center 6 participants Est. completion 2021-05-27 1 site Stand-aloneOther conditions: Philadelphia Chromosome Negative, Recurrent B Acute Lymphoblastic Leukemia, Refractory B Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT03518242
Molecular Profile of Breast Cancer in Ugandan Patients With Stage IIB-III Breast Cancer
Not yet reported Fred Hutchinson Cancer Center 100 participants Est. completion 2022-05-04 2 sites Stand-aloneOther conditions: Breast Cancer Female, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Invasive Breast Carcinoma, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8View official trial listing → -
Completed NCT NCT03520842
Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer
Not yet reported Stanford University 22 participants Est. completion 2022-06-15 1 site Stand-aloneOther conditions: KRAS Gene Mutation, Metastatic Malignant Neoplasm in the Brain, Recurrent Non-Small Cell Lung Carcinoma, Stage IV Non-Small Cell Lung Cancer AJCC v7View official trial listing → -
Completed NCT NCT03522415
Study of Safety and Efficacy of HLX01+MTX in Patients With Rheumatoid Arthritis
Not yet reported Shanghai Henlius Biotech 275 participants Est. completion 2020-09-11 1 site Stand-aloneOther conditions: Moderately to Severely Active Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03529279
CNG Staging Compared With 8th UICC of NPC for Treatment Decision-marking and Selection of Chemotherapy and Radiotherapy
Not yet reported Sun Yat-sen University 1324 participants Est. completion 2026-06-12Other conditions: Nasopharyngeal CarcinomaView official trial listing → -
Completed NCT NCT03531073
Multicentre ObservatioNal Initiative in Treat to Target Outcomes in Psoriatic Arthritis
University of Oxford 446 participants Est. completion 2024-12-31 1 siteOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT03531593
Dose Effect Relationship of MTX and IBD
Children's Mercy Hospital Kansas City 64 participants Est. completion 2018-05-31 1 siteOther conditions: Inflammatory Bowel Diseases, Liver Fibroses, MethotrexateView official trial listing → -
Status unknown NCT NCT03535402
Measurement of the Structural Efficacy in Active RA Patients Treated With Sarilumab in Combination With MTX and Naive to Biologics
Not yet reported Gaylis, Norman B., M.D. 20 participants Est. completion 2020-12-30 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03535519
Rheumatoid Arthritis Response to Methotrexate
Juan Carlos Nieto 50 participants Est. completion 2020-08-31 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03549715
NEoadjuvant Dose-dense MVAC In cOmbination With Durvalumab and Tremelimumab in Muscle-invasive Urothelial Carcinoma
Not yet reported, Not yet reported Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie 121 participants Est. completion 2025-09 15 sites Stand-aloneOther conditions: Infiltrating Bladder Urothelial CarcinomaView official trial listing → -
Status unknown NCT NCT03553238
Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALL
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 70 participants Est. completion 2020-08-30 1 site Stand-aloneOther conditions: Leukemia, Acute, Leukemia, T Cell, Leukemia, LymphoblasticView official trial listing → -
Completed NCT NCT03553472
Identifying Young Inflammatory Bowel Disease Patients at Risk for Herpes Zoster
University of Wisconsin, Madison 97 participants Est. completion 2019-05-31 1 siteOther conditions: Herpes Zoster, Inflammatory Bowel Diseases, Crohn Disease, Ulcerative ColitisView official trial listing → -
Status unknown NCT NCT03564470
Precision Diagnosis Directing HDACi and TKI Target Therapy for Adult Ph-like ALL
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 120 participants Est. completion 2023-08-30 1 site Stand-aloneOther conditions: Leukemia, Leukemia, Acute, Leukemia, Lymphoblastic, Leukemia, B-cellView official trial listing → -
Status unknown NCT NCT03564704
Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 80 participants Est. completion 2021-05-30 1 site Stand-aloneOther conditions: Leukemia, Leukemia, Acute, Adult Lymphoblastic Lymphoma, Leukemia, Lymphoblastic, Leukemia, T Cell, Adult Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT03569995
[CREMA]Combination of R-M Followed by R-A in Elderly Patients With Primary CNS Lymphoma
Not yet reported Won Seog Kim 35 participants Est. completion 2025-06 1 site Stand-aloneOther conditions: Primary CNS LymphomaView official trial listing → -
Status unknown NCT NCT03582254
Role of [18F]-FDG Brain PET in Newly Diagnosed Primary Cerebral Lymphoma, in Immunocompetent Patient Older Than 60 Years
Not yet reported Assistance Publique - Hôpitaux de Paris 62 participants Est. completion 2023-05-12 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Active, not recruiting NCT NCT03589326
A Study of Ponatinib Versus Imatinib in Adults With Acute Lymphoblastic Leukemia
Not yet reported Takeda 245 participants Est. completion 2027-07-31 92 sites Stand-aloneOther conditions: Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ALL)View official trial listing → -
Completed NCT NCT03589833
Effectiveness and Safety of Yisaipu Combined With Tripterygium Wilfordii for Active RA
Not yet reported Peking Union Medical College Hospital 504 participants Est. completion 2022-07-27 1 site Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT03599960
Combination Chemotherapy in Patients With Newly Diagnosed BPDCN
Not yet reported Centre Hospitalier Universitaire de Besancon 26 participants Est. completion 2024-11 2 sites Stand-aloneOther conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)View official trial listing → -
Withdrawn NCT NCT03602898
Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell Transplantation
Not yet reported Fred Hutchinson Cancer Center Est. completion 2023-09-17 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid System Neoplasm, Myelodysplastic Syndrome, Myelofibrosis, Myeloproliferative Neoplasm, Recurrent Acute Myeloid Leukemia, Recurrent Hodgkin Lymphoma, Recurrent Non-Hodgkin Lymphoma, Refractory Acute Myeloid Leukemia, Therapy-Related Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03605251
Efficacy and Safety Study of TAS5315 Compared With Placebo in Participants With Rheumatoid Arthritis.
Not yet reported Taiho Pharmaceutical Co., Ltd. 91 participants Est. completion 2020-05-28 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03606707
Efficacy of Fluoroscopic Guided Atlantoaxial Joint Injection on Head and Neck Pain and Sleep Quality in RA Patients
Not yet reported Assiut University 60 participants Est. completion 2018-08-01 2 sites Stand-aloneOther conditions: Pain, Head, Sleep DisturbanceView official trial listing → -
Status unknown NCT NCT03610217
Pragmatic Clinical Trials in Scleroderma
Not yet reported University of West London 400 participants Est. completion 2021-10 1 site Stand-aloneOther conditions: Scleroderma, Systemic, Sclerosis, SystemicView official trial listing → -
Status unknown NCT NCT03613181
ANG1005 in Leptomeningeal Disease From Breast Cancer
Not yet reported Angiochem Inc 150 participants Est. completion 2024-12Other conditions: Leptomeningeal Carcinomatosis, Leptomeningeal Metastases, Brain Metastases, HER2-negative Breast CancerView official trial listing → -
Active, not recruiting NCT NCT03613532
Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN
Not yet reported Jacqueline Garcia, MD 102 participants Est. completion 2030-03-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), MDS/Myeloproliferative Neoplasm-unclassifiable (MDS/MPN-unclassifiable), Hematopoietic Stem Cell TransplantView official trial listing → -
Status unknown NCT NCT03629639
Metformin for Treatment of Psoriasis Combined With Disorders of Glucose and Lipid Metabolism
Not yet reported Central South University 80 participants Est. completion 2020-12-01 Stand-aloneOther conditions: Psoriasis Vulgaris With Metabolic DisordersView official trial listing → -
Completed NCT NCT03635957
Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Gout
Not yet reported Amgen 14 participants Est. completion 2020-10-26 6 sites Stand-aloneOther conditions: GoutView official trial listing → -
Active, not recruiting NCT NCT03643133
Mifamurtide Combined With Post-operative Chemotherapy for Newly Diagnosed High Risk Osteosarcoma Patients
Not yet reported UNICANCER 60 participants Est. completion 2033-10 31 sites Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT03649061
COBRA-Slim With or Without Fast Access to TNF Blockade for Remission Induction in Early RA
Not yet reported P. Verschueren 276 participants Est. completion 2022-07-01 19 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Completed NCT NCT03652961
Rheumatoid Arthritis Memory B Cells and Abatacept
Not yet reported NYU Langone Health 25 participants Est. completion 2021-09-27 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03660059
A Study to Assess Safety and Efficacy of ASP015K in Participants With Rheumatoid Arthritis (RA) Who Had an Inadequate Response or Intolerance to Methotrexate (MTX)
Not yet reported Astellas Pharma China, Inc. 385 participants Est. completion 2021-11-02 43 sites Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT03674424
Avelumab as Neoadjuvant Therapy in Subjects With Urothelial Muscle Invasive Bladder Cancers (AURA Trial)
Not yet reported Jules Bordet Institute 137 participants Est. completion 2025-01-30 10 sites Stand-aloneOther conditions: Non-metastatic Muscle Invasive Bladder CancerView official trial listing → -
Completed NCT NCT03680092
Comparing Cyclophosphamide and Abatacept With Standard of Care Treatment Following Stem Cell Transplantation
Not yet reported Dimitrios Tzachanis, MD PhD 43 participants Est. completion 2023-06-15 1 siteOther conditions: GVHD, Hematologic NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT03684980
LTA Pilot Study of Glucarpidase in Patients With Central Nervous System Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 58 participants Est. completion 2027-11 11 sites Stand-aloneOther conditions: Central Nervous System LymphomaView official trial listing → -
Status unknown NCT NCT03689465
PTCy-ATG vs ATG in Haploidentical HSCT for Acute Graft-versus-host Disease Prophylaxis
Not yet reported Nanfang Hospital, Southern Medical University 260 participants Est. completion 2020-12-31 7 sitesOther conditions: Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT03690895
Long-term Outcome of AIDS-related Primary Central Nervous System Lymphoma Treated With High Dose Methotrexate and Combined Antiretroviral Therapy
Fondation Ophtalmologique Adolphe de Rothschild 51 participants Est. completion 2016-10-01 1 siteOther conditions: Central Nervous System Lymphoma, AIDS Related LymphomaView official trial listing → -
Status unknown NCT NCT03692416
The Effect of Some Drugs Used in Treatment of Vasculitis on the Complement System in Children
Not yet reported Assiut University 70 participants Est. completion 2022-05-11 1 siteOther conditions: VasculitisView official trial listing → -
Completed NCT NCT03696173
Safety Study of Abatacept in Rheumatoid Arthritis Participants
Bristol-Myers Squibb 5800 participants Est. completion 2018-06-29 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03699631
PROACTIVE: Preventing Acute/Chronic GVHD With TocIlizumab Combined With GVHD Prophylaxis Post allogEneic Transplant
Not yet reported Medical College of Wisconsin 29 participants Est. completion 2023-04-01 1 site Stand-aloneOther conditions: Hematologic MalignancyView official trial listing → -
Completed NCT NCT03707535
To Compare the Efficacy, Pharmacokinetics and Safety Between CT-P13 and China Approved Remicade When Co-administered With Methotrexate in Patients With Active Rheumatoid Arthritis
Not yet reported Celltrion 270 participants Est. completion 2021-03-05 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT03710772
Ibrutinib, Rituximab, Venetoclax, and Combination Chemotherapy in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 51 participants Est. completion 2027-03-22 1 site Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Withdrawn NCT NCT03719560
Early Systemic Central Nervous System Prophylaxis in Diffuse Large B-cell Lymphoma
Not yet reported Brown University Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Completed NCT NCT03736044
Reconstitution of CD4+CD25highCD127low/-Tcell
Not yet reported University Hospital of Ferrara 48 participants Est. completion 2017-03-13Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03736161
Safety and Efficacy of Tofacitinib vs Methotrexate in the Treatment of Psoriatic Arthritis
Not yet reported Globe Pharmaceuticals Limited 61 participants Est. completion 2019-09-28 1 siteOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT03737708
A Study Comparing Biologics + Methotrexate With Biologics + Tacrolimus in Patients With Rheumatoid Arthritis (RA)
Not yet reported Astellas Pharma Korea, Inc. 21 participants Est. completion 2020-06-16 10 sitesOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT03739853
Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial
Not yet reported University of Oxford 192 participants Est. completion 2024-10-31 1 site Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Status unknown NCT NCT03746223
Intravitreal Methotrexate and R2(Rituximab & Lenalidomide) Regimen in Newly-diagnosed Primary Vitreoretinal Lymphoma
Not yet reported Peking Union Medical College Hospital 42 participants Est. completion 2025-10-15 1 site Stand-aloneOther conditions: Primary Intraocular LymphomaView official trial listing → -
Completed NCT NCT03757013
A Study to Assess Benefits of Apremilast in Patients With Moderate to Severe Chronic Plaque Psoriasis Followed by Dermatologists Under Real Life Settings in France
Amgen 453 participants Est. completion 2021-09-10 93 sitesOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT03757364
Methotrexate in the Treatment of Distal Interphalangeal Joint Extensor Tendon Enthesopathy in Nail Psoriasis
Ryszard Górecki 32 participants Est. completion 2018-09-30 1 siteOther conditions: Nail PsoriasisView official trial listing → -
Completed NCT NCT03760003
Dose-Ranging Phase 2b Study of ABX464 in Moderate to Severe Ulcerative Colitis
Not yet reported Abivax S.A. 355 participants Est. completion 2021-04-16 130 sitesOther conditions: Ulcerative ColitisView official trial listing → -
Active, not recruiting NCT NCT03769506
ASP-1929 Photoimmunotherapy (PIT) Study in Recurrent Head/Neck Cancer for Patients Who Have Failed at Least Two Lines of Therapy
Not yet reported Rakuten Medical, Inc. 135 participants Est. completion 2025-12 22 sitesOther conditions: Head and Neck CancerView official trial listing → -
Active, not recruiting NCT NCT03775460
Methotrexate and Prednisolone Study in Erythema Nodosum Leprosum
Not yet reported London School of Hygiene and Tropical Medicine 550 participants Est. completion 2025-10-01 7 sites Stand-aloneOther conditions: Erythema Nodosum LeprosumView official trial listing → -
Completed NCT NCT03775824
Faecal Analyses in Rheumatoid Arthritis Therapy
Region Skane 50 participants Est. completion 2019-06-01Other conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT03779854
Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant
Not yet reported Fred Hutchinson Cancer Center 45 participants Est. completion 2027-08-31 9 sites Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Leukemia, Acute Leukemia of Ambiguous Lineage, Acute Lymphoblastic Leukemia, Acute Undifferentiated Leukemia, Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Blastic Plasmacytoid Dendritic Cell Neoplasm, Blasts Under 25 Percent of Bone Marrow Nucleated Cells, Blasts Under 5 Percent of Bone Marrow Nucleated Cells, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome With Excess Blasts-1, Myelodysplastic Syndrome/Acute Myeloid Leukemia, Burkitt Leukemia, Chronic Monocytic Leukemia, Lymphoblastic Lymphoma, Mast Cell Leukemia, Myeloproliferative NeoplasmView official trial listing → -
Terminated NCT NCT03781375
Etanercept Plus Methotrexate Versus Methotrexate Alone in Children With Polyarticular Course Juvenile Rheumatoid Arthritis
Not yet reported Amgen 25 participants Est. completion 2002-06-24 Stand-aloneOther conditions: Juvenile Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03789292
A Study to Compare Efficacy and Safety of CT-P17 With Humira in Patients With Active Rheumatoid Arthritis
Not yet reported Celltrion 648 participants Est. completion 2020-04-24 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT03793478
Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood
Not yet reported, Not yet reported Daiichi Sankyo 65 participants Est. completion 2027-05-01 27 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03797872
Psoriatic Oligoarthritis Intervention With Symptomatic thErapy
Not yet reported University of Oxford 1 participants Est. completion 2020-07-16 1 siteOther conditions: Psoriatic ArthritisView official trial listing → -
Status unknown NCT NCT03802890
Microbial Dysbiosis in Rheumatoid Arthritis
Quadram Institute Bioscience 30 participants Est. completion 2021-07-30 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT03808610
Low-Intensity Chemotherapy and Venetoclax in Treating Patients With Relapsed or Refractory B- or T-Cell Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 53 participants Est. completion 2026-05-05 1 site Stand-aloneOther conditions: Recurrent B Acute Lymphoblastic Leukemia, Recurrent T Acute Lymphoblastic Leukemia, Refractory B Acute Lymphoblastic Leukemia, Refractory T Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT03813147
Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2023-12-31 19 sites Stand-aloneOther conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT03813199
Study of Two Doses of ABX464 in Participants With Moderate to Severe Rheumatoid Arthritis
Not yet reported Abivax S.A. 60 participants Est. completion 2021-04-27 24 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03813771
Targeted Treatment Early With Etanercept + Methotrexate vs.T2T Care for DMARD-naïve Early RA Patients Based on naïve T-cell Stratification
Not yet reported University of Leeds 106 participants Est. completion 2023-02 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03815448
Methotrexate in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitis
Not yet reported Zhujiang Hospital 215 participants Est. completion 2023-12-01 11 sites Stand-aloneOsteoarthritis Other conditions: Effusion Synovial, Knee PainView official trial listing → -
Active, not recruiting NCT NCT03817320
PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma
Not yet reported, Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 24 participants Est. completion 2025-06-30 18 sites Stand-aloneOther conditions: ALL, Childhood, Lymphoblastic Lymphoma, Childhood, Lymphoblastic Leukemia, Acute, ChildhoodView official trial listing → -
Withdrawn NCT NCT03820934
FibroScan ® Study: Assessing Liver Fibrosis in Patients Using Methotrexate for Psoriasis
Not yet reported University Hospitals Cleveland Medical Center Est. completion 2019-05-15 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT03828019
Adalimumab vs. Conventional Immunosuppression for Uveitis Trial
Not yet reported JHSPH Center for Clinical Trials 227 participants Est. completion 2024-09-09 26 sitesOther conditions: UveitisView official trial listing → -
Completed NCT NCT03830203
Comparative Study of BAT1806 to RoActemra® in Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate
Not yet reported Bio-Thera Solutions 621 participants Est. completion 2021-01-05 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03833271
The Efficacy of Influenza Vaccine Program in Children With Juvenile Idiopathic Arthritis. A Single Centre Results From Hungary
Not yet reported University of Pecs 62 participants Est. completion 2019-09-30 1 siteOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Status unknown NCT NCT03840512
An Open Label Study of Multiple Doses of Cannabidiol in the Prevention of Acute Graft-Versus-Host Disease (GVHD)
Not yet reported Kalytera Therapeutics Israel, Ltd. 36 participants Est. completion 2022-12-15 5 sites Stand-aloneOther conditions: Prevention aGVHDView official trial listing → -
Active, not recruiting NCT NCT03842696
Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation
Not yet reported, Not yet reported University of Michigan Rogel Cancer Center 43 participants Est. completion 2026-04-01 7 sites Stand-aloneOther conditions: Hematologic Diseases, Acute Leukemia in Remission, Chronic Myelogenous Leukemia - Chronic Phase, Chronic Myelogenous Leukemia, Accelerated Phase, Chronic Myelogenous Leukemia, Blastic Phase, Myelodysplastic Syndromes, Mantle Cell Lymphoma, Follicular Lymphoma, Diffuse Large B Cell Lymphoma, Non Hodgkin Lymphoma, Graft Vs Host Disease, Graft-versus-host-diseaseView official trial listing → -
Completed NCT NCT03852888
Kinetics of Elimination of Methotrexate and Its Major Metabolite 7-OH-methotrexate for Observant Patients
Not yet reported CHU de Reims 62 participants Est. completion 2021-11-25 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03855007
The Clinical Efficacy and Safety of Iguratimod in RA and Early RA Patients for 6 Months Treatment
Not yet reported Qilu Hospital of Shandong University 400 participants Est. completion 2023-10-31 1 site Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT03860012
Folic Acid in Pediatric Inflammatory Bowel Disease
Not yet reported Le Bonheur Children's Hospital 100 participants Est. completion 2020-05-01 1 siteOther conditions: Inflammatory Bowel DiseasesView official trial listing → -
Terminated NCT NCT03860844
Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia
Not yet reported Sanofi 67 participants Est. completion 2023-05-26 41 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT03863405
Metformin Use in Rheumatoid Arthritis
Not yet reported Ain Shams University 60 participants Est. completion 2020-01-09 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT03864419
Rituximab Hyaluronidase in Combination With Chemotherapy in Treating Aggressive B-cell Lymphoma in Uganda
Not yet reported Fred Hutchinson Cancer Center 18 participants Est. completion 2023-07-26 1 site Stand-aloneOther conditions: Burkitt Lymphoma, KSHV-associated Multicentric Castleman Disease, Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT03871361
Abatacept in Patients With Birdshot HLA A29 Uveitis
Not yet reported Universitaire Ziekenhuizen KU Leuven 15 participants Est. completion 2023-12-01 1 site Stand-aloneOther conditions: Eye Diseases, UveitisView official trial listing → -
Completed NCT NCT03885037
Infliximab Biosimilar for Intravenous Drip Infusion 100 mg "Pfizer" Drug Use Investigation (Rheumatoid Arthritis)
Pfizer 77 participants Est. completion 2024-11-29 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03885388
Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma (GTN) Patients With Score of 5-6
Not yet reported, Not yet reported Women's Hospital School Of Medicine Zhejiang University 300 participants Est. completion 2023-12-31 1 site Stand-aloneOther conditions: Gestational Trophoblastic Tumor, Effects of Chemotherapy, Drug ToxicityView official trial listing → -
Completed NCT NCT03886038
Subunit Vaccine Against Herpes Zoster in RA Patients Treated With JAK-inhibitors (VACCIMIL-ZOSTER)
Not yet reported Region Skane 142 participants Est. completion 2022-02-15 1 siteOther conditions: Rheumatoid Arthritis, Healthy ControlsView official trial listing → -
Status unknown NCT NCT03886233
Treatment Outcome of Uveitis in Autoimmune Diseases
Assiut University 1 participants Est. completion 2021-02Other conditions: Autoimmune UveitisView official trial listing → -
Status unknown NCT NCT03889808
Seroprevalence of Anti-bodies Against Clostridium Difficile Toxins and Prevalence of Asymptomatic Carriage of Clostridium Difficile in IBD Patients.
Hospital Universitari de Bellvitge 500 participants Est. completion 2021-12 1 siteOther conditions: Clostridium Difficile, Inflammatory Bowel DiseasesView official trial listing → -
Active, not recruiting NCT NCT03892785
MEthotrexate Versus TOcilizumab for Treatment of GIant Cell Arteritis: a Multicenter, Randomized, Controlled Trial
Not yet reported Centre Hospitalier Universitaire Dijon 230 participants Est. completion 2027-01 1 siteOther conditions: Giant Cell ArteritisView official trial listing → -
Status unknown NCT NCT03904680
Studying the Effect of Methotrexate Alone Versus Methotrexate and Vitamin D on the Cardiovascular Risk of Psoriatic Patients
Not yet reported Cairo University 30 participants Est. completion 2019-11Other conditions: PsoriasisView official trial listing → -
Terminated NCT NCT03912818
Durvalumab and Standard Chemotherapy Before Surgery in Treating Patients With Variant Histology Bladder Cancer
Not yet reported Stanford University 7 participants Est. completion 2022-08-11 1 site Stand-aloneOther conditions: Bladder Adenocarcinoma, Bladder Mixed Adenocarcinoma, Bladder Squamous Cell Carcinoma, Bladder Urothelial Carcinoma, Infiltrating Bladder Urothelial Carcinoma Sarcomatoid Variant, Infiltrating Bladder Urothelial Carcinoma With Giant Cells, Infiltrating Bladder Urothelial Carcinoma With Glandular Differentiation, Infiltrating Bladder Urothelial Carcinoma With Trophoblastic Differentiation, Infiltrating Bladder Urothelial Carcinoma, Clear Cell Variant, Infiltrating Bladder Urothelial Carcinoma, Micropapillary Variant, Infiltrating Bladder Urothelial Carcinoma, Nested Variant, Infiltrating Bladder Urothelial Carcinoma, Plasmacytoid VariantView official trial listing → -
Terminated NCT NCT03913559
Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia
Not yet reported St. Jude Children's Research Hospital 5 participants Est. completion 2025-09-15 2 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT03913728
Methotrexate Use Improvement in Rheumatoid Arthritis Using Biomarker Feedback
Not yet reported University of Manchester 57 participants Est. completion 2022-07-31 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT03914625
A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 6720 participants Est. completion 2027-09-30 228 sites Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, B Lymphoblastic Lymphoma, Down SyndromeView official trial listing → -
Status unknown NCT NCT03925233
Breast Cancer Treatment Based on Organ-like Culture
Xijing Hospital 300 participants Est. completion 2021-12-15 1 siteOther conditions: Breast Cancer OrganoidsView official trial listing → -
Status unknown NCT NCT03932058
Proteomics Research of Osteosarcoma
Second Affiliated Hospital, Zhejiang University, School of Medicine 400 participants Est. completion 2020-09-01 1 siteObstructive sleep apnea Other conditions: ProteomicsView official trial listing → -
Status unknown NCT NCT03944096
Efficacy and Safety of Fecal Microbiota Transplantation in Patients With Rheumatoid Arthritis Refractory to Methotrexate
Not yet reported Peking Union Medical College Hospital 30 participants Est. completion 2020-07-31 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT03959241
TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)
Not yet reported Medical College of Wisconsin 431 participants Est. completion 2022-09-19 39 sitesOther conditions: Acute Leukemia, Chronic Myelogenous Leukemia (CML), Myelodysplasia, LymphomaView official trial listing → -
Completed NCT NCT03960177
Glucarpidase After High-Dose Methotrexate in Patients With Osteosarcoma
Not yet reported OHSU Knight Cancer Institute 11 participants Est. completion 2025-12-31 3 sitesObstructive sleep apneaView official trial listing → -
Status unknown NCT NCT03962465
Phase I Study of Inotuzumab With Augmented BFM Re-Induction for Patients With Relapsed/Refractory B-cell ALL
Not yet reported University of Virginia 36 participants Est. completion 2026-07 4 sites Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03964090
Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS)
Not yet reported National Cancer Institute (NCI) 48 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Central Nervous System Lymphoma, Secondary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT03964259
Reduced IV Fluids to Improve Clearance of HDMTX in Children w/Lymphoma or Acute Lymphoblastic Leukemia
Not yet reported Virginia Commonwealth University 10 participants Est. completion 2022-12-28 1 siteOther conditions: Lymphoma, Acute Lymphoblastic Leukemia, Pediatric Cancer, Pediatric ALL, Pediatric LymphomaView official trial listing → -
Completed NCT NCT03965728
Study to Investigate Safety, Tolerability, Pharmacokinetics, and Drug-drug Interaction of Multiple Oral Doses of BAY1830839 in Healthy Male Participants
Not yet reported Bayer 67 participants Est. completion 2022-05-11 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT03980483
Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate
Not yet reported GlaxoSmithKline 1537 participants Est. completion 2022-08-16 76 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Withdrawn NCT NCT03982992
Allogeneic Donor Lymphocyte Infusions Combined With Blinatumomab
Not yet reported Ludwig-Maximilians - University of Munich Est. completion 2021-11-30 1 site Stand-aloneOther conditions: B Cell Precursor Acute Lymphoblastic Leukemia With Mixed Chimerism or Minimal Residual Disease After Allogeneic Stem Cell Transplantation, B-Cell Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia in Remission, Acute Lymphoblastic Leukemia, AdultView official trial listing → -
Completed NCT NCT03994731
Study of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled Gout
Not yet reported Amgen 152 participants Est. completion 2022-04-11 60 sites Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT04009525
Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major: A Multicenter, Prospective Clinical Study
Not yet reported First Affiliated Hospital of Guangxi Medical University 823 participants Est. completion 2023-10-31 1 site Stand-aloneOther conditions: Thalassemia MajorView official trial listing → -
Active, not recruiting NCT NCT04018937
Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation
Not yet reported Emory University 43 participants Est. completion 2026-11 15 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT04022980
Nivolumab Consolidation in Older (≥ 65) Patients With Primary CNS Lymphoma
Not yet reported Wake Forest University Health Sciences 14 participants Est. completion 2025-12-22 4 sitesOther conditions: Brain and Nervous System, Eye and OrbitView official trial listing → -
Completed NCT NCT04038970
Efficacy and Safety Study of KN019 in Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate
Not yet reported Jiangsu Alphamab Biopharmaceuticals Co., Ltd 145 participants Est. completion 2022-07-28 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04042792
Characterization of Adalimumab Concentrations in Pediatric Patients With Inflammatory Rheumatic Disease With and Without Methotrexate
University Hospital, Basel, Switzerland 28 participants Est. completion 2021-06-28 2 sitesOther conditions: Rheumatic DiseasesView official trial listing → -
Completed NCT NCT04046250
Phase 2a Study to Evaluate Suppression of Methotrexate-induced Mucositis by TK112690
Not yet reported Tosk, Inc. 22 participants Est. completion 2020-03-31 3 sites Stand-aloneOther conditions: MucositisView official trial listing → -
Terminated NCT NCT04047693
Neoadjuvant Dose Dense MVAC in MIBC and Locally Advanced Urothelial Carcinoma
Not yet reported Pusan National University Yangsan Hospital 24 participants Est. completion 2023-10-31 1 site Stand-aloneOther conditions: Muscle Invasive Bladder Cancer, Urothelial Carcinoma, Neoadjuvant ChemotherapyView official trial listing → -
Status unknown NCT NCT04066803
Optimal MTX Dose With Folic Acid Randomized Case-control Trial
Not yet reported Sun Yat-sen University 160 participants Est. completion 2020-07-30 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04068246
The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Rheumatoid Arthritis Patients
Not yet reported, Not yet reported Sadat City University 120 participants Est. completion 2021-02-28 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT04077957
Treat-to-target Strategy in Ankylosing Spondylitis Using Etanercept and Conventional Synthetic DMARDs
Not yet reported Nanfang Hospital, Southern Medical University 100 participants Est. completion 2022-07-02 1 site Stand-aloneOther conditions: Ankylosing Spondylitis, SpondyloarthritisView official trial listing → -
Completed NCT NCT04082416
Study of Recombinant Human B Lymphocyte(RC18) Administered Subcutaneously to Subjects With Systemic Lupus Erythematosus(SLE)
Not yet reported RemeGen Co., Ltd. 335 participants Est. completion 2022-06-30 1 site Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Status unknown NCT NCT04083066
Open Randomized Prospective Clinical Study of R-FPD Versus R-MAD Regimen in the Treatment of Primary Central Nervous System Lymphoma
Not yet reported Mingzhi Zhang 20 participants Est. completion 2024-04-01 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Terminated NCT NCT04084223
JAKPOT (JAK Inhibitors and Predictors of Outcome in RheumaToid Arthritis)
Not yet reported University Hospital, Montpellier 51 participants Est. completion 2024-09-24 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT04095858
Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005)
Not yet reported Oncoimmune, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 11 participants Est. completion 2021-11-05 4 sites Stand-aloneOther conditions: Hematopoietic Stem Cell Transplantation, Acute Graft Versus Host Disease, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT04096846
Effect of Vitamin D Diffiency on Oral Mucosa in Patients Recieving Methotrexate Chemotherapy
Assiut University 100 participants Est. completion 2020-12-01Other conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT04101578
Clinical Prognosis and Progression of Myasthenia Gravis Patients
Da, Yuwei, M.D. 2000 participants Est. completion 2024-12-31 1 siteOther conditions: Myasthenia GravisView official trial listing → -
Completed NCT NCT04108468
GOLimumab and Methotrexate Versus Methotrexate in Very Early PsA
Not yet reported The Leeds Teaching Hospitals NHS Trust 84 participants Est. completion 2023-07 1 site Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Status unknown NCT NCT04109300
Preemptive HLA Genotyping for the Safe Use of Infliximab-combination Therapy in Inflammatory Bowel Disease
Not yet reported Western University, Canada 162 participants Est. completion 2023-09-01 1 site Stand-aloneOther conditions: Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn DiseaseView official trial listing → -
Terminated NCT NCT04118556
Decidua Stroma Cells for Steroid Resistent Acute Graft-versus-host Disease After Allo-HSCT
Not yet reported Mats Remberger 12 participants Est. completion 2026-04-29 4 sitesOther conditions: GVHD, AcuteView official trial listing → -
Status unknown NCT NCT04120350
R2-MTX With Lenalidomide Maintenance in Newly-diagnosed PCNSL:a Multicenter Phase Ib/II Stuty
Not yet reported, Not yet reported Peking Union Medical College Hospital 47 participants Est. completion 2024-08 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Status unknown NCT NCT04120831
TOLERA: Tolerance Enhancement in RA
Not yet reported University of Erlangen-Nürnberg Medical School 20 participants Est. completion 2022-12-01 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT04124861
Withdraw Drug in Stable IgG4-Related Disease
Not yet reported Peking Union Medical College Hospital 138 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Withdrawn NCT NCT04127721
Itacitinib for the Prevention of Graft Versus Host Disease in Patients Undergoing Donor Stem Cell Transplantation
Not yet reported M.D. Anderson Cancer Center Est. completion 2020-09-22 1 site Stand-aloneOther conditions: Allogeneic Stem Cell Transplant Recipient, Hematologic and Lymphocytic Disorder, Hematopoietic and Lymphoid Cell NeoplasmView official trial listing → -
Status unknown NCT NCT04129710
A Trial to Compare Ibrutinib Versus Lenalidomide in Combination With MRE-chemotherapy for Adult Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL)
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 120 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Recurrent/RefractoryPrimary Central Nervous System Lymphoma (PCNSL)View official trial listing → -
Status unknown NCT NCT04131231
Safety and Effectiveness of MPCD Therapy on the Treatment of Malignant Pleural Effusion
Not yet reported Peking Union Medical College 248 participants Est. completion 2021-06-15 Stand-aloneOther conditions: Lung Cancer, Breast Cancer, Malignant Pleural EffusionView official trial listing → -
Status unknown NCT NCT04136262
Tripterygium Wilfordii Hook F and Methotrexate for Postmenopausal Women With Rheumatoid Arthritis
Not yet reported, Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 300 participants Est. completion 2022-12 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04154852
ADalimumab in Persistent Early Oligoarthrits Study (ADEOS)
Not yet reported University of Leeds 22 participants Est. completion 2017-01-16 1 site Stand-aloneOther conditions: OligoarthritisView official trial listing → -
Completed NCT NCT04157010
Tocilizumab REMission in Early RA
Not yet reported University of Leeds 20 participants Est. completion 2016-03-29 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT04168619
MTX-related Liver Toxicity in Psoriasis Patients, Using Ultrasound-based Techniques as a Diagnostic Tool
The University of Hong Kong 50 participants Est. completion 2021-07-12 1 siteOther conditions: Psoriasis, Liver FibrosisView official trial listing → -
Completed NCT NCT04169828
The Ondansetron Premedication Trial in Juvenile Idiopathic Arthritis
Not yet reported University of British Columbia 52 participants Est. completion 2025-01-17 11 sites Stand-aloneOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Completed NCT NCT04170504
Efficacy of Chinese Herbal Medicine Qing Re Huo Xue in Patients With Rheumatoid Arthritis
Not yet reported, Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 204 participants Est. completion 2022-06-28 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04177173
Methotrexate and Statins With Methotrexate Alone in the Treatment of Rheumatoid Arthritis
Not yet reported King Edward Medical University 100 participants Est. completion 2018-12-14 1 site Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT04179513
A Study to Evaluate the Safety and Tolerability of Multiple Doses of Gerilimzumab in Rheumatoid Arthritis Patients
Not yet reported Genor Biopharma Co., Ltd. 24 participants Est. completion 2021-04 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04192617
A Study to Evaluate the Safety and Efficacy of SM03 in Patients With Rheumatoid Arthritis Receiving Methotrexate
Not yet reported SinoMab BioScience Ltd 156 participants Est. completion 2016-02-03 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04196868
Methotrexate and Metformin in Rheumatoid Arthritis Patients
Not yet reported University Hospital, Bordeaux 128 participants Est. completion 2026-06-16 12 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Status unknown NCT NCT04196920
Methotrexate-associated Anti-TNF Combination Therapy, the Neglected One !
University Hospital, Montpellier 200 participants Est. completion 2020-11-30 1 siteOther conditions: Chronic Inflammatory Bowel DiseaseView official trial listing → -
Completed NCT NCT04204603
A Study Evaluating the Efficacy and Safety of CKD-506 in Adult Subjects With Moderate-to-Severe Rheumatoid Arthritis and Inadequate Response to Methotrexate
Not yet reported Chong Kun Dang Pharmaceutical 122 participants Est. completion 2019-10-29 38 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT04205292
Cesarean Scar Pregnancy Managed by Dilatation and Evacuation (D&E) Versus Hysteroscopic Surgery
Not yet reported Federico II University 54 participants Est. completion 2022-01-15 1 site Stand-aloneOther conditions: Scar; Previous Cesarean SectionView official trial listing → -
Suspended NCT NCT04205734
Methotrexate Polyglutamate Measurements in Patients With Inflammatory Bowel Disease
Boston Children's Hospital 100 participants Est. completion 2024-12-31 1 siteOther conditions: IBDView official trial listing → -
Completed NCT NCT04214626
R-CHOP Combined With Lenalidomide in the First-line Treatment for Patients With Diffuse Large B Cell Lymphoma
Not yet reported Henan Cancer Hospital 60 participants Est. completion 2025-04-19 1 site Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Completed NCT NCT04227366
Study of the Efficacy and Safety of BCD-089 in Combination With Methotrexate in Patients With Active Rheumatoid Arthritis
Not yet reported Biocad 154 participants Est. completion 2022-03-01 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04230213
A Comparative Study Between PF-06410293 and Humira® in Combination With Methotrexate in Participants With Active Rheumatoid Arthritis
Not yet reported Pfizer 455 participants Est. completion 2021-06-22 72 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04237103
Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo
Not yet reported University Hospital, Bordeaux 32 participants Est. completion 2025-11-04 4 sites Stand-aloneOther conditions: VitiligoView official trial listing → -
Not yet recruiting NCT NCT04239859
Outcomes With Treatment and Withdraw of Secukinumab in Patients With Plaque Psoriasis
Not yet reported Singapore General Hospital 40 participants Est. completion 2027-12 1 siteOther conditions: Plaque PsoriasisView official trial listing → -
Completed NCT NCT04247815
Study of ATI-450 Plus Methotrexate (MTX) vs MTX Alone in Patients With Moderate to Severe RA
Not yet reported Aclaris Therapeutics, Inc. 25 participants Est. completion 2021-02-04 5 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04259138
Determination of the Optimal Treatment Target in Ulcerative Colitis
Not yet reported Alimentiv Inc. 672 participants Est. completion 2026-04-13 58 sitesOther conditions: Colitis, UlcerativeView official trial listing → -
Completed NCT NCT04267536
An Observational Study to Evaluate Impact of CRP-Level on Real World Effectiveness of Upadacitinib as Monotherapy or in Combination With MTX in Adult Participants With Rheumatoid Arthritis
AbbVie 534 participants Est. completion 2022-02-01 52 sitesOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Completed NCT NCT04268394
A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677
Not yet reported Celgene 48 participants Est. completion 2021-06-02 1 site Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Completed NCT NCT04283955
A Retrospective Cohort Study: The Influence of MTHFR C677T and A1298C on the High-dose Methotrexate-Related Toxicities in Pediatric Patients With Non-Hodgkin Lymphoma
Sun Yat-sen University 93 participants Est. completion 2019-03-01 1 siteOther conditions: Pediatric NHLView official trial listing → -
Status unknown NCT NCT04294511
Study of Camrelizumab in Combination With Neoadjuvant Chemotherapy in the Treatment of Osteosarcoma
Not yet reported Sun Yat-sen University 75 participants Est. completion 2023-09-16 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Status unknown NCT NCT04299971
Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients
Not yet reported Shanghai Zhongshan Hospital 130 participants Est. completion 2023-12-31 1 site Stand-aloneOther conditions: Takayasu Arteritis, Methotrexate, Inhibition, TreatmentView official trial listing → -
Status unknown NCT NCT04308343
The Aromatase Inhibitor and Gnrh Antagonist Versus Methotrexate for Management of Undisturbed Ectopic Pregnancy
Not yet reported Assiut University 120 participants Est. completion 2022-09-01Other conditions: Ectopic PregnancyView official trial listing → -
Terminated NCT NCT04311567
Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung Disease
Not yet reported Vastra Gotaland Region 3 participants Est. completion 2024-03-26 3 sites Stand-aloneOther conditions: Rheumatoid Arthritis, Interstitial Lung Disease Due to Systemic Disease (Disorder), RA, ILDView official trial listing → -
Status unknown NCT NCT04312815
A Study Assessing the Efficacy and Safety of SM03 in Patients With Active Rheumatoid Arthritis Receiving MTX
Not yet reported SinoMab BioScience Ltd 510 participants Est. completion 2022-07 1 site Stand-aloneOther conditions: Rheumatoid Arthritis(RA)View official trial listing → -
Status unknown NCT NCT04314193
Effectiveness of Methotrexate Versus Prednisone as First-line Therapy for Pulmonary Sarcoidosis
Not yet reported Erasmus Medical Center 138 participants Est. completion 2026-07 17 sites Stand-aloneOther conditions: Sarcoidosis, PulmonaryView official trial listing → -
Completed NCT NCT04326894
Methorexate and Knee Osteoarthritis
Not yet reported University of Alexandria 128 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Pain Reduction, Physical Function ImprovementView official trial listing → -
Active, not recruiting NCT NCT04329325
Blinatumomab and Tyrosine Kinase Inhibitor Therapy in People With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 17 participants Est. completion 2027-03 2 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Philadelphia Chromosome-PositiveView official trial listing → -
Status unknown NCT NCT04341545
Letrozole in Tubal Ectopic Pregnancy
Not yet reported Queen Mary Hospital, Hong Kong 214 participants Est. completion 2025-03-31 1 site Stand-aloneOther conditions: Tubal PregnancyView official trial listing → -
Status unknown NCT NCT04352465
Efficacy and Safety of MTX-loaded Nanoparticles to Treat Severe COVID-19 Patients
Not yet reported, Not yet reported Azidus Brasil 42 participants Est. completion 2020-11-30 1 site Stand-aloneOther conditions: COVID-19View official trial listing → -
Status unknown NCT NCT04356118
Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis
Not yet reported Hui Bu 30 participants Est. completion 2023-06 Stand-aloneOther conditions: Leptomeningeal MetastasisView official trial listing → -
Status unknown NCT NCT04356222
Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis
Not yet reported Hui Bu 30 participants Est. completion 2023-06 Stand-aloneOther conditions: Leptomeningeal Metastasis, DurvalumabView official trial listing → -
Completed NCT NCT04360785
Effect of Two Methotrexate in Sync With the First Adalimumab to Prevent the Immunisation Anti Ada in Spondyloarthritis
Not yet reported Assistance Publique - Hôpitaux de Paris 124 participants Est. completion 2023-02-27 17 sites Stand-aloneOther conditions: SpondyloarthritisView official trial listing → -
Status unknown NCT NCT04379219
Surgery Alone Versus Methotrexate Before Surgery in Cesarean Scar Pregnancy
Not yet reported Mansoura University 56 participants Est. completion 2020-12 1 siteOther conditions: Cesarean Scar PregnancyView official trial listing → -
Completed NCT NCT04383743
Pembrolizumab and Combination Chemotherapy Before Surgery for the Treatment of Muscle-Invasive Bladder Cancer
Not yet reported University of Washington 17 participants Est. completion 2025-03-04 1 site Stand-aloneOther conditions: Stage II Bladder Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8, Muscle Invasive Bladder CarcinomaView official trial listing → -
Active, not recruiting NCT NCT04384692
Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis
Not yet reported Fred Hutchinson Cancer Center 53 participants Est. completion 2030-04-23 1 site Stand-aloneOther conditions: Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Completed NCT NCT04401774
Nivolumab Maintenance in Newly Diagnosed PCNSL With Persistent CSF Circulating Tumor DNA After Completion of First-Line Chemotherapy
Not yet reported Memorial Sloan Kettering Cancer Center 14 participants Est. completion 2026-01-22 7 sites Stand-aloneOther conditions: Primary Central Nervous System Lymphoma (PCNSL)View official trial listing → -
Completed NCT NCT04413617
TO ASSESS THE EFFICACY AND SAFETY OF PF-06650833, PF-06651600, AND TOFACITINIB ALONE AND IN COMBINATION IN PARTICIPANTS WITH ACTIVE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATE
Not yet reported Pfizer 460 participants Est. completion 2022-02-07 144 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT04423471
Neuroinflammation, Affective and Cognitive Symptoms in Major Depression and Psoriasis
Germans Trias i Pujol Hospital Est. completion 2022-12 1 siteOther conditions: Psoriasis, Neuroinflammation, Major Depressive Disorder, Cognitive Symptom, Immunological AbnormalityView official trial listing → -
Completed NCT NCT04433650
Pictorial Support in Person-centred Care for Children (PicPecc)
Not yet reported Göteborg University 29 participants Est. completion 2025-03-31 1 site Stand-aloneOther conditions: Childhood Cancer, Communication, Symptoms and SignsView official trial listing → -
Withdrawn NCT NCT04434118
Anti-rheumatic Drug Use and Risk of COVID-19 Infection in Rheumatoid Arthritis Patients
Sadat City University Est. completion 2021-12-30 1 siteOther conditions: Rheumatoid Arthritis, COVIDView official trial listing → -
Active, not recruiting NCT NCT04435288
Spondyloarthritis: Inducing Drug-free Remission by Early TNF-alpha Blockade
Not yet reported University Hospital, Ghent 90 participants Est. completion 2028-12-31 6 sitesOther conditions: Peripheral SpondyloarthritisView official trial listing → -
Active, not recruiting NCT NCT04446962
LOC-R01 Study of Lenalidomide and Ibrutinib in Association With Rituximab-Methotrexate Procarbazine Vincristin (R-MPV)
Not yet reported, Not yet reported Institut Curie 118 participants Est. completion 2035-08-30 28 sitesOther conditions: Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, PrimaryView official trial listing → -
Status unknown NCT NCT04453345
TPM Regimen (Thalidomide, Prednisone and Methotrexate) in LGLL
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 42 participants Est. completion 2025-05-20 9 sites Stand-aloneOther conditions: T-LGL Leukemia, Clpd-NkView official trial listing → -
Status unknown NCT NCT04464642
Tofacitinib Versus Methotrexate as the First Line DMARD in the Treatment of Rheumatoid Arthritis
Not yet reported Dr. Mohammad Mamun Khan 110 participants Est. completion 2020-09 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT04469829
Methotrexate Versus Secukinumab Safety in Psoriasis Patients With Metabolic Syndrome
Not yet reported Universita di Verona 70 participants Est. completion 2022-12-31 1 siteMetabolic syndrome Other conditions: PsoriasisView official trial listing → -
Terminated NCT NCT04470453
Association Between Methotrexate Erythrocyte Polyglutamate Concentration and Biological Drug Concentration and Clinical Response in Rheumatoid Arthritis Patients Treated With Subcutaneous Injectable Methotrexate and a First Biological Drug
Not yet reported Centre Hospitalier Universitaire de Saint Etienne 16 participants Est. completion 2024-04-04 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT04475731
Ponatinib in Adult Ph+ ALL Patients With MRD Positivity or Hematological Relapse
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 67 participants Est. completion 2024-11 22 sites Stand-aloneOther conditions: Philadelphia-Positive ALL, Acute Lymphoblastic Leukemia, in RelapseView official trial listing → -
Status unknown NCT NCT04481815
Rituximab Plus Methotrexate With or Without Lenalidomide in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 240 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: PCNSLView official trial listing → -
Status unknown NCT NCT04482543
Repeated Methotrexate for Proliferative Vitreoretinopathy Grade C
Not yet reported, Not yet reported Shahid Beheshti University of Medical Sciences 74 participants Est. completion 2021-09-01 1 siteOther conditions: Proliferative VitreoretinopathyView official trial listing → -
Active, not recruiting NCT NCT04483466
Methotrexate Treatment of Arthritis Caused by Chikungunya Virus (MARCH)
Not yet reported George Washington University 150 participants Est. completion 2027-08-30 1 site Stand-aloneOther conditions: Investigate the Effect(s) of Methotrexate Treatment on Arthritis Disease SeverityView official trial listing → -
Completed NCT NCT04486027
Can Cytokines be Used as an Activation Marker
Maltepe University 60 participants Est. completion 2018-12-15 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT04488237
Vitamin D and Methotrexate Adverse Effects
Assiut University 50 participants Est. completion 2021-12Other conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT04493762
Liver Fibrosis and Gut Microbiota in Patients With Psoriasis Vulgaris and Rheumatoid Arthritis on Methotrexate
The University of Hong Kong 600 participants Est. completion 2022-12-11Other conditions: Psoriasis Vulgaris, Rheumatoid Arthritis, Fibrosis, LiverView official trial listing → -
Terminated NCT NCT04501614
A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported Takeda 11 participants Est. completion 2024-07-19 64 sites Stand-aloneOther conditions: Pediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL), Ph+ Mixed Phenotype Acute Leukemia (MPAL), Philadelphia Chromosome-Like ALL (Ph-like ALL)View official trial listing → -
Active, not recruiting NCT NCT04506554
A Study of Risk Enabled Therapy After Neoadjuvant Immunochemotherapy for Bladder Cancer
Not yet reported Fox Chase Cancer Center 81 participants Est. completion 2028-11 4 sites Stand-aloneOther conditions: Muscle-Invasive Bladder CarcinomaView official trial listing → -
Status unknown NCT NCT04514393
Ibrutinib With Methotrexate and Temozolomide for Patients With Newly Diagnosed Primary CNS Lymphoma
Not yet reported Huiqiang Huang 33 participants Est. completion 2024-06-01 3 sites Stand-aloneOther conditions: Primary Central Nervous System Lymphoma, PCNSL, Non Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT04516655
A Phase II Trail of Chidamide ,Rituximab and Methotrexate in Lymphoma Patients
Not yet reported Fudan University 51 participants Est. completion 2023-08-30 Stand-aloneOther conditions: Central Nervous System LymphomaView official trial listing → -
Active, not recruiting NCT NCT04530565
Testing the Use of Steroids and Tyrosine Kinase Inhibitors With Blinatumomab or Chemotherapy for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia in Adults
Not yet reported National Cancer Institute (NCI) 348 participants Est. completion 2028-07-01 211 sites Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1View official trial listing → -
Completed NCT NCT04532736
Comparison of Methylprednisolone or Methotrexate in the Maintenance Treatment of Nasal Polyposis
Not yet reported Dokuz Eylul University 41 participants Est. completion 2019-05-05 1 site Stand-aloneOther conditions: Nasal PolyposisView official trial listing → -
Completed NCT NCT04539470
Study to Evaluate the Safety and Pharmacokinetics of Efmarodocokin Alfa in Combination With Standard of Care in Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported Genentech, Inc. 18 participants Est. completion 2023-02-24 8 sites Stand-aloneOther conditions: Acute Graft-versus-host DiseaseView official trial listing → -
Completed NCT NCT04540250
Stratification of Oral Ulcers in Rheumatoid Arthritis Patients Kept on Methotrexate
Beni-Suef University 804 participants Est. completion 2019-08Other conditions: Methotrexate Adverse Reaction, Oral MucositisView official trial listing → -
Active, not recruiting NCT NCT04562558
Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia
Not yet reported xiang yang 228 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: Gestational Trophoblastic Tumor, Gestational Trophoblastic Neoplasia, Stage I Gestational Trophoblastic Tumor, Stage II Gestational Trophoblastic Tumor, Stage III Gestational Trophoblastic Tumor, Invasive Mole, ChoriocarcinomaView official trial listing → -
Completed NCT NCT04571697
A Study of Comparing Rates of Dementia and Alzheimer's Disease in Participants Initiating Methotrexate Versus Those Initiating Anti-tumor Necrosis Factor (TNF)-Alpha Therapy
Janssen Research & Development, LLC 34647 participants Est. completion 2020-10-27 1 siteOther conditions: Dementia, Alzheimer DiseaseView official trial listing → -
Completed NCT NCT04577781
A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 6 Weeks in Adults With Moderately to Severely Active Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Not yet reported Lakefront Biotherapeutics NV 28 participants Est. completion 2021-04-07 9 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT04579848
Methotrexate in Erosive Inflammatory Hand Osteoarthritis
Not yet reported Diakonhjemmet Hospital 163 participants Est. completion 2026-12 1 siteOsteoarthritisView official trial listing → -
Status unknown NCT NCT04588818
Adalimumab Plus Methotrexate for the Treatment of Pediatric Uveitis
Not yet reported Sun Yat-sen University 30 participants Est. completion 2023-12-31 1 site Stand-aloneOther conditions: UveitisView official trial listing → -
Active, not recruiting NCT NCT04609046
Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma
Not yet reported National Cancer Institute (NCI) 47 participants Est. completion 2027-04-01 56 sites Stand-aloneOther conditions: Primary Diffuse Large B-Cell Lymphoma of the Central Nervous SystemView official trial listing → -
Status unknown NCT NCT04610476
Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic Arthritis
Not yet reported University of Erlangen-Nürnberg Medical School 270 participants Est. completion 2025-10-19 1 site Stand-aloneOther conditions: Psoriatic Arthritis, Withdrawal, ReductionView official trial listing → -
Status unknown NCT NCT04610567
Treatment of Patients With Mild Coronavirus-19 (COVID-19) Disease With Methotrexate Associated to LDL Like Nanoparticles (Nano-COVID19)
Not yet reported, Not yet reported University of Sao Paulo General Hospital 100 participants Est. completion 2021-07-15 3 sites Stand-aloneOther conditions: Coronavirus, Inflammation, Covid19View official trial listing → -
Status unknown NCT NCT04616872
Treatment of Patients With Atherosclerotic Disease With Methotrexate-associated to LDL Like Nanoparticles
Not yet reported, Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2023-10-12 2 sites Stand-aloneCardiovascular disease Other conditions: Atherosclerosis, InflammationView official trial listing → -
Status unknown NCT NCT04622956
GVHD Prophylaxis With Methotrexate in Haploidentical HCT Using Posttransplant Cyclophosphamide
Not yet reported, Not yet reported University of Sao Paulo General Hospital 47 participants Est. completion 2025-12 4 sites Stand-aloneOther conditions: Graft Vs Host Disease, Hematopoietic NeoplasmView official trial listing → -
Status unknown NCT NCT04649697
Rebamipide (Regular & Nanoparticulated) vs. Clobetasol in Management of Methotrexate-Induced Oral Ulceration in Rheumatoid Arthritis Patients
Not yet reported Cairo University 39 participants Est. completion 2023-12-30 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04667988
JAK2 Mutation May Predict Response and Guide First Line Treatment in Rheumatoid Arthritis
Not yet reported Mansoura University 76 participants Est. completion 2020-05-01 1 site Stand-aloneOther conditions: Response Assessment in Newly Diagnosed RA Patients at 3rd Month Was Evaluated by DAS28 and ACR in Relation to JAK ExpressionView official trial listing → -
Suspended NCT NCT04668768
HM-178: Assessing Methods for Improvement in Methotrexate Toxicity Management and Detection of Central Nervous System Involvement of Aggressive Lymphoma
Not yet reported Fox Chase Cancer Center 3 participants Est. completion 2025-04 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Status unknown NCT NCT04677868
MTX and Steroid for aGVHD Treatment
Not yet reported Peking University People's Hospital 30 participants Est. completion 2022-06 1 site Stand-aloneOther conditions: Acute GVH DiseaseView official trial listing → -
Completed NCT NCT04691505
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines (DREAM) - Methotrexate vs Hydroxychloroquine
Brigham and Women's Hospital 133553 participants Est. completion 2021-08-31 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT04726553
Nature of Anifrolumab Impact on Vaccine-Emergent Immunity in SLE
Not yet reported Oklahoma Medical Research Foundation 20 participants Est. completion 2024-12-31 5 sitesOther conditions: Systemic Lupus Erythematosus (SLE)View official trial listing → -
Completed NCT NCT04749160
Smart Marker Annunciating Response to Rheumatologic Treatments SMART²T
Centre Hospitalier Universitaire de Saint Etienne 26 participants Est. completion 2022-02-20 13 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT04752163
DS-1594b With or Without Azacitidine, Venetoclax, or Mini-HCVD for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 17 participants Est. completion 2023-11-08 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell Neoplasm, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelomonocytic Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Chronic Myelomonocytic Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT04752748
Power Doppler in Hand Joints of Early RA Patients
Federal University of São Paulo 48 participants Est. completion 2016-08Other conditions: Early Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT04756713
Second Uterine Evacuation for Low-risk Gestational Trophoblastic Neoplasia
Not yet reported Brigham and Women's Hospital 150 participants Est. completion 2025-12-31 7 sitesOther conditions: Gestational Trophoblastic Neoplasia, Molar Pregnancy, Gestational Trophoblastic Tumor, Non-MetastaticView official trial listing → -
Completed NCT NCT04758689
Laser Acupuncture in Rheumatoid Arthritis Geriatric Patients
Not yet reported Cairo University 60 participants Est. completion 2020-12-22 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT04762498
A Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients With Uncontrolled Gout (FORWARD OL)
Not yet reported Amgen 54 participants Est. completion 2023-12-20 12 sites Stand-aloneOther conditions: Uncontrolled Gout, Chronic GoutView official trial listing → -
Completed NCT NCT04772313
Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapy
Not yet reported Amgen 11 participants Est. completion 2023-04-24 15 sites Stand-aloneOther conditions: Uncontrolled GoutView official trial listing → -
Status unknown NCT NCT04778618
Individualized Dose Study of ATG in Haploidentical Hematopoietic Stem Cell Transplantation
Not yet reported Chinese PLA General Hospital 63 participants Est. completion 2024-01-14 1 site Stand-aloneOther conditions: Haploidentical Hematopoietic Stem Cell TransplantationView official trial listing → -
Status unknown NCT NCT04798755
Efficacy, Safety and Costs of Methotrexate, Adalimumab, or Their Combination in Non-infectious Non-anterior Uveitis
Not yet reported Hospital San Carlos, Madrid 192 participants Est. completion 2025-10-01 14 sites Stand-aloneOther conditions: UveitisView official trial listing → -
Terminated NCT NCT04809623
Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)
Not yet reported Gilead Sciences 3 participants Est. completion 2022-10-18 5 sites Stand-aloneOther conditions: Cutaneous Lupus ErythematosusView official trial listing → -
Status unknown NCT NCT04811911
Evaluation of the Effect of Narrowband UVB Versus Methotrexate on Serum TWEAK Level in Psoriasis
Not yet reported Aswan University Hospital 30 participants Est. completion 2021-12-15 1 siteOther conditions: PsoriasisView official trial listing → -
Withdrawn NCT NCT04830878
Methotrexate For The Prevention and Treatment of Proliferative Vitreoretinopathy in Pediatric Patients
Not yet reported Stanford University Est. completion 2024-04 1 site Stand-aloneOther conditions: Proliferative VitreoretinopathyView official trial listing → -
Completed NCT NCT04838704
Ruxolitinib With Calcineurin Inhibitor and Methotrexate vs. Calcineurin Inhibitor Plus Methotrexate and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis for HLA-haploidentical Hematopoietic Stem Cell Transplantation
Not yet reported Zhejiang University 215 participants Est. completion 2024-12-01 1 site Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Withdrawn NCT NCT04845035
Pediatric-Inspired Chemotherapy Plus Tyrosine Kinase Inhibitor in Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Not yet reported University of Michigan Rogel Cancer Center Est. completion 2029-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04872790
Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia
Not yet reported OHSU Knight Cancer Institute 20 participants Est. completion 2027-12-02 1 site Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Mixed Phenotype Acute Leukemia, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Mixed Phenotype Acute LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04881838
CCCG-ALCL-2020 for Chinese Children and Adolescents With Newly Diagnosed High-risk ALCL
Not yet reported Children's Cancer Group, China 172 participants Est. completion 2029-03-01 1 site Stand-aloneOther conditions: Pediatric Anaplastic Large Cell LymphomaView official trial listing → -
Status unknown NCT NCT04895423
Evaluation of the Effectiveness and Safety of Immunosuppressive and Biological Therapy of Atopic Dermatitis in Childhood
Not yet reported National Medical Research Center for Children's Health, Russian Federation 160 participants Est. completion 2023-07-25 1 site Stand-aloneOther conditions: Atopic DermatitisView official trial listing → -
Active, not recruiting NCT NCT04898894
Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 37 participants Est. completion 2027-09 8 sites Stand-aloneOther conditions: Acute Leukemia of Ambiguous Lineage in Relapse, Acute Myeloid Leukemia, in Relapse, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT04899453
Intravitreal MTX and ZR Regimen in Newly Diagnosed PVRL
Not yet reported Peking Union Medical College Hospital 42 participants Est. completion 2024-08-01 1 site Stand-aloneOther conditions: Primary Vitreoretinal LymphomaView official trial listing → -
Active, not recruiting NCT NCT04909801
A Study to Compare the Response to Treatment With Abatacept vs Adalimumab, on Background Methotrexate, in Adults With Early, Seropositive, and Shared Epitope-positive Rheumatoid Arthritis and an Inadequate Response to Methotrexate
Not yet reported Bristol-Myers Squibb 338 participants Est. completion 2027-09-01 75 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT04914741
A Multicentre, Parallel Arm, Open-label Trial of Frontline R-CHOP/Pola-RCHP and Glofitamab in Younger, Higher Risk Patients With Diffuse Large B Cell Lymphoma (DLBCL)
Not yet reported, Not yet reported Peter MacCallum Cancer Centre, Australia 80 participants Est. completion 2025-07 15 sites Stand-aloneOther conditions: Diffuse Large B Cell Lymphoma, High-grade B-cell LymphomaView official trial listing → -
Completed NCT NCT04916847
Comparative Analysis of Anti-COVID-19 (Severe Acute Respiratory Syndrome) Humoral and Memory T Cell Responses in Children With Various Degrees of Immunosuppression:
Assistance Publique - Hôpitaux de Paris 205 participants Est. completion 2022-12-07 1 siteOther conditions: Immune ResponseView official trial listing → -
Status unknown NCT NCT04927000
The Role of Tofacitinib in Steroid Withdrawal in Rheumatoid Arthritis
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 170 participants Est. completion 2023-12-30 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT04931368
OptiMATe: De-escalated Induction Treatment in Primary CNS Lymphoma
Not yet reported Klinikum Stuttgart 331 participants Est. completion 2028-11 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT04934579
Rituximab,Methotrexate and Lenalidomide in Newly Diagnosed Primary Central Nervous System Lymphoma
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 17 participants Est. completion 2022-11-15 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT04942860
The Evaluation of Vitiligous Lesions Repigmentation After Topical Administration of Methotrexate in Patients With Active Vitiligo
Not yet reported Nicolaus Copernicus University 25 participants Est. completion 2023-08-31 1 siteOther conditions: Non-segmental VitiligoView official trial listing → -
Status unknown NCT NCT04944524
Comparison of Tofacitinib and Methotrexate in the Maintained Treatment of GPA
Not yet reported Shanghai Zhongshan Hospital 66 participants Est. completion 2024-07-01 1 siteOther conditions: Granulomatosis With PolyangiitisView official trial listing → -
Active, not recruiting NCT NCT04947319
Study of Tirabrutinib (ONO-4059) in Patients With Primary Central Nervous System Lymphoma (PROSPECT Study)
Not yet reported Ono Pharmaceutical Co., Ltd. 119 participants Est. completion 2027-03-31 39 sites Stand-aloneOther conditions: Refractory Primary Central Nervous System Lymphoma, Primary CNS LymphomaView official trial listing → -
Status unknown NCT NCT04958538
MTX and Steroid for III-IV aGVHD Treatment
Not yet reported Peking University People's Hospital 30 participants Est. completion 2023-01-30 1 site Stand-aloneOther conditions: Acute Graft Versus Host DiseaseView official trial listing → -
Active, not recruiting NCT NCT04960579
P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma
Not yet reported Poseida Therapeutics, Inc. 275 participants Est. completion 2042-03 23 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT04960644
MTX and Steroid as First-line Therapy for aGVHD
Not yet reported Peking University People's Hospital 157 participants Est. completion 2022-12-31 1 siteOther conditions: Acute GVH DiseaseView official trial listing → -
Withdrawn NCT NCT04961801
Acalabrutinib for GVHD Prophylaxis in Allogeneic Hematopoietic Stem Cell Transplantation in Lymphomas and Leukemia
Not yet reported, Not yet reported Shin Mineishi Est. completion 2030-01 Stand-aloneOther conditions: Lymphoma, LeukemiaView official trial listing → -
Completed NCT NCT04965597
Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)
Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2026-02-18 24 sites Stand-aloneOther conditions: Bone Marrow Failure Syndrome, Congenital Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Hereditary Sideroblastic Anemia, Paroxysmal Nocturnal Hemoglobinuria, Shwachman-Diamond Syndrome, Hematologic Neoplasm With Germline GATA2 Mutation, Hematologic Neoplasm With Germline SAMD9 Mutation, Hematologic Neoplasm With Germline SAMD9L MutationView official trial listing → -
Status unknown NCT NCT04967950
An Efficacy Study of Secukinumab In Enthesitis of Psoriatic Arthritis Patients
Not yet reported Peking Union Medical College Hospital 60 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Completed NCT NCT04989296
Informative Value of Determining the Level of NF-κB Translocation in Lymphocyte Populations in Children With Psoriasis
Not yet reported National Medical Research Center for Children's Health, Russian Federation 120 participants Est. completion 2020-01-15 1 site Stand-aloneOther conditions: Psoriasis VulgarisView official trial listing → -
Terminated NCT NCT05000216
COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 258 participants Est. completion 2024-03-28 29 sites Stand-aloneOther conditions: Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE), Pemphigus Vulgaris, Multiple Sclerosis (MS), Systemic Sclerosis (SSc), Pediatric SLE, Juvenile Idiopathic Arthritis (JIA), Juvenile Dermatomyositis (JDM), Pediatric-Onset Multiple Sclerosis (POMS)View official trial listing → -
Status unknown NCT NCT05008887
Fractional CO2 Laser-assisted Cutaneous Delivery of Methotrexate Versus 5-fluorouracil in Stable Non-segmental Vitiligo
Not yet reported Assiut University 50 participants Est. completion 2023-04 Stand-aloneOther conditions: VitiligoView official trial listing → -
Status unknown NCT NCT05014555
Sustained Humoral and Cell-Mediated Immunogenicity of COVID-19 Vaccines in Patients With Inflammatory Bowel Disease
GI Alliance 400 participants Est. completion 2024-01 4 sitesOther conditions: Inflammatory Bowel DiseasesView official trial listing → -
Status unknown NCT NCT05015335
The Efficacy and Safety of Adalimumab in Non-infectious Anterior Pediatric Uveitis With Peripheral Vascular Leakage
Not yet reported Peking Union Medical College Hospital 50 participants Est. completion 2023-07 1 siteOther conditions: Uveitis, Anterior, AdalimumabView official trial listing → -
Completed NCT NCT05021159
Assessing the Ontogeny of P-glycoprotein Expression in Blood of Pediatric Leukemic Patients
Tanta University 20 participants Est. completion 2021-08-01 3 sitesOther conditions: Acute Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT05022797
Reduction of MTX Levels After Glucarpidase Treatment in DLBCL Patients at Risk of CNS
Not yet reported Fundacion CRIS de Investigación para Vencer el Cáncer 3 participants Est. completion 2022-11-22 2 sites Stand-aloneOther conditions: Diffuse Large B-Cell Lymphoma, Drug ToxicityView official trial listing → -
Status unknown NCT NCT05026229
A Study of Dasatinib Plus Reduced Intensive Consolidation Chemotherapy in Ph+ Adult ALL
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 60 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma, Philadelphia-Positive Acute Lymphoblastic Leukemia, ALL, AdultView official trial listing → -
Terminated NCT NCT05032183
Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2024-07-31 1 site Stand-aloneOther conditions: Recurrent Adult Lymphoblastic Lymphoma, Recurrent B Acute Lymphoblastic Leukemia, Recurrent T Acute Lymphoblastic Leukemia, Refractory B Acute Lymphoblastic Leukemia, Refractory Lymphoblastic Lymphoma, Refractory T Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT05036577
A Dose-escalating Pilot Study of Orelabrutinib for Newly-diagnosed PCNSL
Not yet reported Huashan Hospital 13 participants Est. completion 2025-03-30 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Status unknown NCT NCT05049473
Treatment of Mature B-ALL and Burkitt Lymphoma (BL) in Adult Patients. BURKIMAB-14.
Not yet reported PETHEMA Foundation 100 participants Est. completion 2024-01 29 sites Stand-aloneOther conditions: Mature B-Cell Leukemia Burkitt Type, Burkitt Lymphoma (BL), Unclassifiable Lymphoma Between DCBL and BLView official trial listing → -
Completed NCT NCT05051137
Real-World Emulation of the SWEFOT Trial
Karolinska Institutet 509 participants Est. completion 2020-11-16 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05054426
Intermediate Dose of IV MTX as CNS Prophylaxis for High Risk DLBCL
Not yet reported Peking Union Medical College Hospital 488 participants Est. completion 2025-10-08 1 site Stand-aloneOther conditions: Diffuse Large B Cell Lymphoma, Central Nervous System LymphomaView official trial listing → -
Status unknown NCT NCT05057130
Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors
Not yet reported, Not yet reported Blokhin's Russian Cancer Research Center 50 participants Est. completion 2024-12 1 site Stand-aloneObstructive sleep apnea Other conditions: Neoplasms, Connective Tissue, Neoplasms, Connective and Soft Tissue, Sarcoma, Sarcoma of BoneView official trial listing → -
Completed NCT NCT05069714
One or Two Week Methotrexate Discontinuation on Efficacy of Influenza Vaccination in Rheumatoid Arthritis.
Not yet reported Seoul National University Hospital 184 participants Est. completion 2022-09-30 3 sites Stand-aloneOther conditions: Rheumatoid Arthritis, Autoimmune Diseases, Influenza, Vaccine ReactionView official trial listing → -
Status unknown NCT NCT05078294
Results in Real Clinical Practice of Treatment of Moderate-severe Atopic Dermatitis
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 300 participants Est. completion 2024-11-01 7 sitesOther conditions: Dermatitis, AtopicView official trial listing → -
Status unknown NCT NCT05090410
Efficacy and Safety of Selective JAK 1 Inhibitor Filgotinib in Active Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate
Not yet reported Atsushi Kawakami 400 participants Est. completion 2023-12-31 1 siteOther conditions: Rheumatoid Arthritis, JAK Inhibitor, IL-6 Inhibitor, Musculoskeletal Ultrasound, BiomarkerView official trial listing → -
Status unknown NCT NCT05097443
Orelabrutinib, Rituximab and Combination Chemotherapy in Newly-diagnosed Aggressive B-cell Non-Hodgkin Lymphoma
Not yet reported Shandong Provincial Hospital 130 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements, High Grade B-Cell Lymphoma, Not Otherwise Specified, Diffuse Large B-cell Lymphoma, Mantle Cell Lymphoma, B-cell NonHodgkin LymphomaView official trial listing → -
Completed NCT NCT05117593
Investigate the Safety, Tolerability and Pharmacokinetics of FBL-MTX
Not yet reported SOLFARCOS - Pharmaceutical and Cosmetic Solutions Ltd 32 participants Est. completion 2021-10-19 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05120687
Corticosteroid Combining Noncorticosteroid Systemic Immunomodulatory Therapy in VKH
Sun Yat-sen University 200 participants Est. completion 2025-10-06 1 siteOther conditions: Vogt Koyanagi Harada Disease (VKH)View official trial listing → -
Status unknown NCT NCT05121298
Discontinuation of Methotrexate in Rheumatoid Arthritis Patients Achieving Clinical Remission by Treatment With Upadacitinib Plus Methotrexate
Not yet reported Atsushi Kawakami 155 participants Est. completion 2024-09-30 1 siteOther conditions: Rheumatoid Arthritis, JAK Inhibitor, Musculoskeletal Ultrasound, BiomarkerView official trial listing → -
Completed NCT NCT05133297
The Safety and Efficacy of TLL-018 in Active Rheumatoid Arthritis
Not yet reported Hangzhou Highlightll Pharmaceutical Co., Ltd 101 participants Est. completion 2023-05-30 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05135858
Dose Dense Re-challenge of High Dose Methotrexate With Glucarpidase for Relapsed Primary Central Nervous System Lymphoma
Not yet reported Assistance Publique - Hôpitaux de Paris 18 participants Est. completion 2025-07-31 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Status unknown NCT NCT05136274
Evaluation of Ipsilateral Tubal Patency After Conservative Medical or Surgical Treatment.
Not yet reported EDGREM Investimentos 204 participants Est. completion 2023-08-17 1 siteOther conditions: Ectopic PregnancyView official trial listing → -
Active, not recruiting NCT NCT05137262
A Phase II Multicenter Study of Chemotherapy Versus Chemotherapy Plus Durvalumab (MEDI 4736) in Patients With Lymph Node Positive Urothelial Carcinoma of the Bladder
Not yet reported M.D. Anderson Cancer Center 12 participants Est. completion 2028-08-31 2 sites Stand-aloneOther conditions: Urothelial Carcinoma, Bladder CancerView official trial listing → -
Active, not recruiting NCT NCT05146739
Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane
Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2027-05-09 19 sites Stand-aloneOther conditions: Acute Myeloid Leukemia Post Cytotoxic Therapy, Myelodysplastic Syndrome Post Cytotoxic Therapy, Myeloid Leukemia Associated With Down Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Mixed Phenotype Acute Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT05149365
Sitagliptin for Prevention of aGVHD After Alternative Donor Transplation
Not yet reported The First Affiliated Hospital of Soochow University 190 participants Est. completion 2025-06-16 1 siteOther conditions: Acute-graft-versus-host Disease, Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT05149768
Open Label Extension Study of Brentuximab Vedotin in Early dcSSc
Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 3 participants Est. completion 2025-07-23 1 site Stand-aloneOther conditions: Diffuse Cutaneous Systemic SclerosisView official trial listing → -
Active, not recruiting NCT NCT05157971
Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia
Not yet reported City of Hope Medical Center 24 participants Est. completion 2027-04-12 1 site Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, Ph-Like Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT05164770
Study of Zanubrutinib, Rituximab and Combination Chemotherapy in Newly-diagnosed Aggressive B-cell Non-Hodgkin Lymphoma
Not yet reported Shandong Provincial Hospital 160 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: High Grade B-Cell Lymphoma, Not Otherwise Specified, High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements, Diffuse Large B Cell Lymphoma, B-cell Non Hodgkin Lymphoma, Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT05166304
Rebamipide in Patients With Active Rheumatoid Arthritis
Not yet reported, Not yet reported October 6 University 60 participants Est. completion 2025-09-01 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05166967
Targeted Dose Study of ATG in Haploidentical Hematopoietic Stem Cell Transplantation
Not yet reported Chinese PLA General Hospital 204 participants Est. completion 2025-07-29 1 site Stand-aloneOther conditions: Haploidentical Hematopoietic Stem Cell TransplantationView official trial listing → -
Active, not recruiting NCT NCT05192889
Trial Treating Relapsed Acute Lymphoblastic Leukemia With Venetoclax and Navitoclax
Not yet reported, Not yet reported St. Jude Children's Research Hospital 35 participants Est. completion 2027-02 2 sites Stand-aloneOther conditions: Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT05208034
Medical Treatment in Ectopic Tubal Pregnancy
Not yet reported Nishtar Medical University 100 participants Est. completion 2021-07-30 1 site Stand-aloneOther conditions: Ectopic PregnancyView official trial listing → -
Status unknown NCT NCT05214066
Efficacy and Safety Study of 4-Day ATG Regimen for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT
Not yet reported Chinese PLA General Hospital 60 participants Est. completion 2022-08-01 1 site Stand-aloneOther conditions: aGVHD, cGVHDView official trial listing → -
Status unknown NCT NCT05245448
Tetrandrine in the Treatment of Rheumatoid Arthritis
Not yet reported Peking University People's Hospital 240 participants Est. completion 2024-03-31 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05247203
Telitacicept Study in Chinese Subjects With Systemic Lupus Erythematosus
Not yet reported RemeGen Co., Ltd. 92 participants Est. completion 2023-11-13 19 sites Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Completed NCT NCT05249426
A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer
Not yet reported Boehringer Ingelheim 48 participants Est. completion 2026-06-22 25 sites Stand-aloneOther conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)View official trial listing → -
Terminated NCT NCT05263505
Baricitinib for the Treatment of Ocular Mucous Membrane Pemphigoid
Not yet reported Washington University School of Medicine 2 participants Est. completion 2023-09-11 1 siteOther conditions: Mucous Membrane Pemphigoid, Cicatrizing ConjunctivitisView official trial listing → -
Status unknown NCT NCT05267431
Outcomes of Biological Therapy on Rheumatoid Arthritis
Sohag University 200 participants Est. completion 2023-10 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05279417
ATI-450 Plus Methotrexate (MTX) Versus Placebo Plus MTX in Participants With Moderate to Severe Active Rheumatoid Arthritis (RA)
Not yet reported Aclaris Therapeutics, Inc. 251 participants Est. completion 2023-10-11 50 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05300009
Efficacy and Safety of Topical Methotrexate Gel 1% Coupled With Microneedling in Treatment of Warts
Not yet reported Assiut University 68 participants Est. completion 2023-08-15 Stand-aloneOther conditions: WartsView official trial listing → -
Not yet recruiting NCT NCT05303727
Allogeneic Hematopoietic Stem Cell Transplantation for 4/M Neuroblastoma
Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 64 participants Est. completion 2027-08 1 site Stand-aloneOther conditions: NeuroblastomaView official trial listing → -
Active, not recruiting NCT NCT05303792
Comparing Inotuzumab Combined With Low Intensity Chemotherapy Plus Blinatumomab to Usual Chemotherapy Plus Blinatumomab in Older Adults With CD22+ B-cell Acute Lymphoblastic Leukemia
Not yet reported Alliance for Clinical Trials in Oncology 68 participants Est. completion 2029-05 72 sites Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, B Lymphoblastic LymphomaView official trial listing → -
Terminated NCT NCT05306353
CD40L Antagonism in Rheumatoid Arthritis (RA)
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 2 participants Est. completion 2025-07-28 5 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05313061
MTX Hold During Covid-19 Booster
Not yet reported Seoul National University Hospital 40 participants Est. completion 2022-12-30 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05315128
Intralesional Versus Intramuscular Methotrexate for Non-melanoma Skin Cancers
Not yet reported Zagazig University 60 participants Est. completion 2021-12-06 1 siteOther conditions: Non-melanoma Skin CancersView official trial listing → -
Active, not recruiting NCT NCT05316701
Precision-T: A Randomized Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies
Not yet reported Orca Biosystems, Inc. 187 participants Est. completion 2026-07 19 sitesOther conditions: Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Mixed Phenotype Acute Leukemia, Undifferentiated Leukemia, Myelodysplastic Syndrome, Acute Leukemia, Therapy-Related Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT05320159
Treatment Effectiveness Among Psoriasis Patients Treated With Cosentyx (Secukinumab)
Novartis Pharmaceuticals 17743 participants Est. completion 2021-03-31 1 siteOther conditions: PsoriasisView official trial listing → -
Withdrawn NCT NCT05320380
A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat
Not yet reported, Not yet reported Children's Oncology Group Est. completion 2023-09-01 Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Recurrent T Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory B Acute Lymphoblastic Leukemia, Refractory Mixed Phenotype Acute Leukemia, Refractory T Acute Lymphoblastic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT05347641
Penpulimab Combined With RMA Treatment of Primary Diagnosis of Primary Central Nervous System Lymphoma
Not yet reported The First Affiliated Hospital with Nanjing Medical University 23 participants Est. completion 2029-06-01 Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Active, not recruiting NCT NCT05353829
Methotrexate in Patients with Early Rheumatoid Arthritis
Not yet reported Region Västerbotten 212 participants Est. completion 2026-12-31 13 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05363891
Natrunix or Placebo in Combination With Methotrexate in Rheumatoid Arthritis
Not yet reported XBiotech, Inc. 243 participants Est. completion 2024-10-31 26 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05363917
Natrunix Versus Methotrexate in Rheumatoid Arthritis
Not yet reported XBiotech, Inc. 150 participants Est. completion 2023-02-15Other conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05370690
Retrospective Comparison of the Efficacy of Methotrexate and Azathioprine as Background Treatment for Uveitis of Undetermined Origin: Single-centre Retrospective Study From 2005 to 2020
University Hospital, Brest 70 participants Est. completion 2022-11-01 1 siteOther conditions: UveitisView official trial listing → -
Completed NCT NCT05374785
Efficacy and Safety Study Comparing CPL409116 to Placebo in Participants With Active Rheumatoid Arthritis
Not yet reported Celon Pharma SA 106 participants Est. completion 2024-05-27 10 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05380934
A Clinical Trial of Safety and Tolerance of TQH3821 Tablets in Adult Healthy Subjects
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 63 participants Est. completion 2023-05-20 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05386290
A Multicentered Prospective Cohort Study of Chinese IBD Patients
Peking Union Medical College Hospital 200 participants Est. completion 2023-12 1 siteOther conditions: Ulcerative Colitis, Crohn DiseaseView official trial listing → -
Status unknown NCT NCT05390749
Sequential Treatment With RO-MTX After Pomalidomide, Orelabrutinib, Rituximab (POR) in Newly-diagnosed PCNSL
Not yet reported Peking Union Medical College Hospital 50 participants Est. completion 2026-04-01 3 sites Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT05392179
A Study in Subjects With Retinitis Pigmentosa
Not yet reported Aldeyra Therapeutics, Inc. 8 participants Est. completion 2023-06-23 1 siteObstructive sleep apneaView official trial listing → -
Status unknown NCT NCT05393050
Efficacy and Safety of Colquhounia Root Tablet in Patients With Rheumatoid Arthritis
Not yet reported Quan Jiang 120 participants Est. completion 2024-06 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Enrolling by invitation NCT NCT05395949
A Randomized Controlled Study of Conservative Treatment of Granulomatous Lobular Mastitis Combined With Psychiatric Disorders
Not yet reported Wuhan University 50 participants Est. completion 2027-01-30 1 site Stand-aloneOther conditions: Breast Diseases, Mastitis Granulomatous, Psychiatric DisorderView official trial listing → -
Status unknown NCT NCT05398224
R-MTX-zanbrutinib in Secondary CNS Lymphoma
Not yet reported Peking University 45 participants Est. completion 2024-05-26 1 site Stand-aloneOther conditions: Secondary Central Nervous System LymphomaView official trial listing → -
Status unknown NCT NCT05408208
Intralesional Injection Of Methotrexate Versus Triamcinolone Acetonid In Treatment Of Localized Psoriasis
Not yet reported Sohag University 30 participants Est. completion 2023-05-21 1 siteOther conditions: Localized PsoriasisView official trial listing → -
Completed NCT NCT05421299
A Study to Assess 7/8 HLA-matched Hematopoietic Stem Cell Transplantation Participants Treated With or Without Abatacept in Combination With a Calcineurin Inhibitor and Methotrexate
Bristol-Myers Squibb 378 participants Est. completion 2021-02-15 1 siteOther conditions: Stem Cell TransplantationView official trial listing → -
Status unknown NCT NCT05424393
Real-World Study on Long-term Treatment With YISAIPU for Fujian RA Patients
The First Affiliated Hospital of Xiamen University 500 participants Est. completion 2025-12-31 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05425654
RL-MPV Followed by BBC HCT Using Autologous Stem Cells and Maintenance Therapy With Nivolumab for Newly Diagnosed PCNSL
Not yet reported National Research Center for Hematology, Russia 30 participants Est. completion 2026-05 1 site Stand-aloneOther conditions: Primary CNS LymphomaView official trial listing → -
Status unknown NCT NCT05426824
The Whole-course Management of Pegaspargase in ENKTL
Not yet reported The First Affiliated Hospital with Nanjing Medical University 72 participants Est. completion 2025-07-15 1 site Stand-aloneOther conditions: Extranodal NK/T Cell LymphomaView official trial listing → -
Status unknown NCT NCT05427175
Evaluation of the Effect of Narrowband UVB Versus Methotrexate on Serum Chitotriosidase Level in Psoriasis
Not yet reported Aswan University Hospital 30 participants Est. completion 2023-09-15 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT05429450
Thyroid Associated Orbitopathy Treatment by Methotrexate Against Triamcinolone Periocular Injections
Not yet reported Cairo University 18 participants Est. completion 2022-07-15 1 site Stand-aloneOther conditions: Thyroid Associated OrbitopathyView official trial listing → -
Completed NCT NCT05445440
A Study to Assess the Effects of BMS-986371 on the Drug Levels of Methotrexate in the Presence and Absence of Sulfasalazine
Not yet reported Bristol-Myers Squibb 30 participants Est. completion 2022-11-23 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT05447520
Montelukast Use in Rheumatoid Arthritis
Not yet reported Noha Mansour 92 participants Est. completion 2022-12-30 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT05457556
Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome
Not yet reported Children's Oncology Group 66 participants Est. completion 2027-07-07 63 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT05458531
Monitoring of Inflammatory Conditions
University of Nottingham 664 participants Est. completion 2023-02-08 1 siteOther conditions: Inflammatory Disease, Crohn Disease, Ulcerative Colitis, Rheumatoid Arthritis, System; Lupus Erythematosus, Psoriatic Arthritis, Reactive Arthritis, Inflammatory Arthritis, PsoriasisView official trial listing → -
Completed NCT NCT05460832
Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA
Not yet reported Modern Biosciences Ltd 248 participants Est. completion 2024-01-03 46 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05485571
Efficacy of Combined Microneedling With Methotrexate in Treatment of Alopecia Areata
Not yet reported Sohag University 30 participants Est. completion 2023-02-01 1 siteOther conditions: Alopecia AreataView official trial listing → -
Completed NCT NCT05489224
A Study to Compare Efficacy and Safety of CT-P47 and RoActemra in Patients With Rheumatoid Arthritis
Not yet reported Celltrion 471 participants Est. completion 2023-11-23 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT05494593
A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)
Not yet reported Takeda Est. completion 2025-08-29 8 sites Stand-aloneOther conditions: Mucopolysaccharidosis (MPS), Hunter SyndromeView official trial listing → -
Status unknown NCT NCT05508815
Modified Zhiwang Decoction Combined With Methotrexate in the Treatment of Early Rheumatoid Arthritis
Not yet reported Beijing University of Chinese Medicine 150 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Active, not recruiting NCT NCT05522582
Methotrexate Combined With Immunotherapy During Radiotherapy for Solid Tumors
Not yet reported Yancheng First People's Hospital 50 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT05533372
MAD Study of IA-14069
Not yet reported ILAb Co., Ltd. 78 participants Est. completion 2025-10-15 1 site Stand-aloneOther conditions: Healthy, Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05535686
Methotrexate Adherence in Rheumatoid Arthritis Patients
Beni-Suef University 300 participants Est. completion 2022-01-01 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05543122
Drug Concentrations in Breast Milk and Prediction of Blood Levels of the Breastfed Infants
The Hospital for Sick Children 39 participants Est. completion 2024-03-31 1 siteOther conditions: Breast FeedingView official trial listing → -
Status unknown NCT NCT05549284
Orelabrutinib,Rituximab and Methotrexate in Newly-diagnosed Primary Central Nervous System Lymphoma(PCNSL)
Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 36 participants Est. completion 2026-05-30 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT05557110
Reduced-dose Chemotherapy Followed by Blinatumomab in Induction Therapy of Newly Diagnosed Non-elderly Ph-B-ALL
Not yet reported Chen Suning 35 participants Est. completion 2024-03-31 1 site Stand-aloneOther conditions: B Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT05567380
Comparative Study of Janus Kinase (JAK) Inhibitors Vs Tumor Necrosis Factor (TNF) Inhibitors in Rheumatoid Arthritis
Sohag University 150 participants Est. completion 2023-06Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05575297
A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy Subjects
Not yet reported Seoul National University Hospital 12 participants Est. completion 2022-05-09 1 site Stand-aloneOther conditions: Drug InteractionView official trial listing → -
Status unknown NCT NCT05576532
Venetoclax Plus IM2 Regimen for Relapsed and Refractory T Lymphoblastic Lymphoma/Leukemia
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 30 participants Est. completion 2025-10-10 1 site Stand-aloneOther conditions: T-lymphoblastic Lymphoma, Relapsed Disease, Refractory Lymphoma, Refractory Leukemia, Safety, Efficacy, SelfView official trial listing → -
Status unknown NCT NCT05578378
Cladribine Combined With G-CSF and Cytarabine as a Salvage Treatment in R/R ALL
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 32 participants Est. completion 2024-12-31 1 siteOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT05579769
Pediatric Study of GVHD Ppx w/o Calcineurin Inhibitors After Day60 Post First Allo HSCT for Hematological Malignancies.
Not yet reported St. Jude Children's Research Hospital 3 participants Est. completion 2024-05-08 1 site Stand-aloneOther conditions: Hematologic Malignancy, Myeloid MalignancyView official trial listing → -
Status unknown NCT NCT05594680
Cilostazol and Methotrexate in Rheumatoid Arthritis
Not yet reported Tanta University 70 participants Est. completion 2024-11-01 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT05600426
A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)
Not yet reported Boston Children's Hospital 53 participants Est. completion 2029-12 52 sitesOther conditions: Severe Aplastic AnemiaView official trial listing → -
Completed NCT NCT05602675
A Drug Interaction Study of LY3871801 in Healthy Participants
Not yet reported Eli Lilly and Company 39 participants Est. completion 2023-03-29 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05604885
A Dose-range Study of the Safety and Efficacy of Treatment in Adult Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate
Not yet reported SynAct Pharma Aps 125 participants Est. completion 2023-08-28 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05615012
A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants
Not yet reported Bristol-Myers Squibb 76 participants Est. completion 2023-12-13 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT05616871
An Observational Study to Assess Change in Disease Activity and Treatment Patterns of Upadacitinib When Given Alone or Co-Administered With Methotrexate in Adult Participants With Active Psoriatic Arthritis
AbbVie 464 participants Est. completion 2026-06-11 89 sitesOther conditions: Psoriatic ArthritisView official trial listing → -
Status unknown NCT NCT05623592
Methotrexate as Remission Maintenance Therapy After Remission-Induction With Tocilizumab and Glucocorticoids in Giant Cell Arteritis
Not yet reported University of Bonn 52 participants Est. completion 2025-11 1 site Stand-aloneOther conditions: Giant Cell ArteritisView official trial listing → -
Status unknown NCT NCT05634915
Clinical Study of rATG Individualized Administration in Haploidentical Hematopoietic Stem Cell Transplantation
Not yet reported The First Affiliated Hospital of Soochow University 90 participants Est. completion 2025-05-01 1 site Stand-aloneOther conditions: Hematopoietic Stem Cell Transplantation, Acute LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05656248
Study of CPX-351 (VYXEOS) in Individuals < 22 Years With Secondary Myeloid Neoplasms
Not yet reported St. Jude Children's Research Hospital 25 participants Est. completion 2028-08 1 site Stand-aloneOther conditions: Myeloid NeoplasmView official trial listing → -
Completed NCT NCT05660655
Efficacy and Safety of Baricitinib for the Treatment of Moderate to Severe Rheumatoid Arthritis
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 94 participants Est. completion 2023-09-30 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Active, not recruiting NCT NCT05663866
Premedication to Reduce Amivantamab Associated Infusion Related Reactions
Not yet reported Janssen Research & Development, LLC 68 participants Est. completion 2027-09-30 36 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT05671497
The Effect of Cilostazol on Rheumatoid Arthritis Patients
Not yet reported, Not yet reported Ain Shams University 70 participants Est. completion 2024-10-01 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05684744
Roflumilast Versus Methotrexate in Psoriasis
Not yet reported, Not yet reported Cairo University 30 participants Est. completion 2023-05-14 1 siteOther conditions: PsoriasisView official trial listing → -
Active, not recruiting NCT NCT05689879
Evaluation of TNF-alpha Antagonists (Infliximab) Withdrawal in Sarcoidosis
Not yet reported Assistance Publique - Hôpitaux de Paris 32 participants Est. completion 2027-01-12 1 siteOther conditions: SarcoidosisView official trial listing → -
Suspended NCT NCT05691478
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 1122 participants Est. completion 2030-03-20 202 sites Stand-aloneObstructive sleep apneaView official trial listing → -
Status unknown NCT NCT05696106
Risk of Incident IMID in Patients Treated With Biologics and Immunosuppressive Drugs for a Single IMID
Assistance Publique - Hôpitaux de Paris 750000 participants Est. completion 2024-01-15 1 siteOther conditions: Inflammatory DiseaseView official trial listing → -
Completed NCT NCT05715190
Development and Feasibility of a Nurse-led Person-centered Education Program
Not yet reported School of Health Sciences Geneva 24 participants Est. completion 2025-09-30 1 siteOther conditions: Self-Management, Behavior, Patient EmpowermentView official trial listing → -
Completed NCT NCT05718583
Effects of Administration of SCFA in Rheumatoid Arthritis Inadequate Responders
Not yet reported NYU Langone Health 20 participants Est. completion 2025-02-20 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT05740449
HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Not yet reported, Not yet reported Princess Maxima Center for Pediatric Oncology Est. completion 2029-10-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) RefractoryView official trial listing → -
Completed NCT NCT05745831
Development and Validation of a Therapeutic Decision Aid in Ectopic Pregnancy: GEUDECID Study
Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 109 participants Est. completion 2024-04-22 15 sitesOther conditions: To Validate a Decision Aid for Ectopic PregnancyView official trial listing → -
Active, not recruiting NCT NCT05761171
A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia
Not yet reported Children's Oncology Group 78 participants Est. completion 2027-12-31 84 sites Stand-aloneOther conditions: Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged, Refractory Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia, Refractory Mixed Phenotype Acute LeukemiaView official trial listing → -
Completed NCT NCT05814627
Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis
Not yet reported AbbVie 487 participants Est. completion 2026-07-15 218 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT05827497
Baricitinib, Methotrexate as Monotherapy or Combination in the Treatment of Rheumatoid Arthritis - an Open Label Randomized Clinical Trial
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 132 participants Est. completion 2024-03-31 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT05839561
Monotherapy With Letrozole in Tubal Pregnancy
Not yet reported Jagiellonian University 22 participants Est. completion 2023-06-30 1 siteOther conditions: Tubal Pregnancy UnrupturedView official trial listing → -
Status unknown NCT NCT05871086
Coenzyme Q10 in Juvenile Idiopathic Arthritis Patients
Not yet reported, Not yet reported Nourhan Elsherif 60 participants Est. completion 2023-12 1 site Stand-aloneOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Status unknown NCT NCT05875285
Methotrexate Iontophoresis Versus Coal Tar Ointement in the Treatment of Primary Palmer Hyper Hidrosis
Not yet reported Cairo University 60 participants Est. completion 2023-10-01 1 site Stand-aloneOther conditions: Hyperhidrosis, IontophoreView official trial listing → -
Active, not recruiting NCT NCT05879419
Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases
Not yet reported University of Sao Paulo General Hospital 2005 participants Est. completion 2032-06-30 1 siteOther conditions: Rheumatoid Arthritis, Spondylitis, Ankylosing, Spondyloarthritis, Systemic Lupus Erythematosus, Sjogren's Syndrome, Systemic Sclerosis, Idiopathic Inflammatory Myopathies, Vasculitis, Systemic, Juvenile Idiopathic Arthritis, Dermatomyositis, Juvenile, Behçet DiseaseView official trial listing → -
Status unknown NCT NCT05889338
Effect of Adalimumab Therapy on Psoriasis Patient
Not yet reported Sohag University 140 participants Est. completion 2024-01 1 siteOther conditions: PsoriasiView official trial listing → -
Status unknown NCT NCT05896007
Zanubrutinib Combined With Rituximab and Chemotherapy for Newly-Diagnosed PCNSLBCL Patients Intolerant to HSCT
Not yet reported Ruijin Hospital 29 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: PCNSLView official trial listing → -
Status unknown NCT NCT05899751
Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate
Protherics Medicines Development Limited 1000 participants Est. completion 2024-12 5 sitesOther conditions: Acute Kidney Injury, Drug ToxicityView official trial listing → -
Status unknown NCT NCT05918718
Assessment of the Efficacy of Letrozole in the Treatment of Ectopic Pregnancy
Not yet reported, Not yet reported Tehran University of Medical Sciences 150 participants Est. completion 2024-12-20 1 site Stand-aloneOther conditions: Ectopic PregnancyView official trial listing → -
Completed NCT NCT05927064
Study Evaluating the Persistence, Efficacy and Tolerability of Methotrexate in Inflammatory Bowel Disease Patients
Central Hospital, Nancy, France 1282 participants Est. completion 2024-01-12 1 siteOther conditions: Inflammatory Bowel Diseases, Crohn Disease, Ulcerative ColitisView official trial listing → -
Not yet recruiting NCT NCT05928754
Prospective CoHoRt Of Non-infectious Intermediate, pOsterior or panuveitiS
Not yet reported Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts 2000 participants Est. completion 2028-08 Stand-aloneOther conditions: Non-infectious UveitisView official trial listing → -
Completed NCT NCT05931042
Neoadjuvant Therapy With Trastuzumab and Chemotherapy and the Resultant Pathologic Complete Response Observed in HER2 Positive Breast Cancer;a Systematic Review
Rawalpindi Medical College 1209 participants Est. completion 2023-06-18 1 siteOther conditions: HER2+ Breast CancerView official trial listing → -
Completed NCT NCT05957120
Subclinical Impairment of Cardiovascular System in Patients With Psoriasis
University Medical Centre Ljubljana 100 participants Est. completion 2022-11-30 1 siteOther conditions: Psoriasis, Inflammation, Endothelial Dysfunction, Metabolic Disturbance, Insulin Resistance, Coagulation Disorder, Thrombocyte DisordersView official trial listing → -
Completed NCT NCT05984381
Efficacy and Safety of add-on Dapsone Versus add-on Methotrexate in Patients With Bullous Pemphigoid
Not yet reported All India Institute of Medical Sciences, Bhubaneswar 62 participants Est. completion 2025-04-01 1 siteOther conditions: Bullous PemphigoidView official trial listing → -
Terminated NCT NCT06001125
Methotrexate for Immune Related Arthritis or Arthralgias (IMPACT 2.1)
Not yet reported AHS Cancer Control Alberta 27 participants Est. completion 2025-10-07 1 site Stand-aloneOther conditions: Arthritis, ArthralgiaView official trial listing → -
Withdrawn NCT NCT06015750
Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia
Not yet reported Alexion Pharmaceuticals, Inc. Est. completion 2030-03-13 Stand-aloneOther conditions: HypophosphatasiaView official trial listing → -
Completed NCT NCT06031194
Pharmacogenomics Effects on High-Dose Methotrexate Clearance in Patients With Diffuse Large B-Cell Lymphoma
Ohio State University Comprehensive Cancer Center 20 participants Est. completion 2025-12-23 1 siteOther conditions: Central Nervous System Lymphoma, Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT06038968
Methotrexate Infusion and Intrasilicone Injection During Diabetic Vitrectomy
Not yet reported Minia University 60 participants Est. completion 2024-01-01 1 site Stand-aloneOther conditions: Diabetic Retinopathy, Vitreomacular TractionView official trial listing → -
Completed NCT NCT06048224
Phase III Clinical Trial Comparing the Safety, Efficacy, and Immunogenicity of Recombinant Anti-interleukin-6 Receptor Humanized Monoclonal Antibody Injection in Combination With Methotrexate and Jamelor ® in the Treatment of Moderate to Severe Rheumatoid Arthritis
Not yet reported Zhejiang Hisun Pharmaceutical Co. Ltd. 669 participants Est. completion 2022-01-31 1 siteOther conditions: Moderate to Severe Active Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT06066554
Tissue and Serum Level of NLRP1, NLRP3 and Il-18 in Early Stages of mf Patients
Not yet reported Cairo University 60 participants Est. completion 2024-05-30Other conditions: Early Disease OnsetView official trial listing → -
Completed NCT NCT06073093
A Study to Evaluate SAR441566 Efficacy and Safety in Adults With Rheumatoid Arthritis
Not yet reported Sanofi 264 participants Est. completion 2025-07-02 102 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT06088147
Methotrexate Versus Triamcinilone Acetonide in Treatment of Recalcitrant Alopecia Areata
Not yet reported Al-Azhar University 34 participants Est. completion 2024-06 1 siteOther conditions: Alopecia AreataView official trial listing → -
Status unknown NCT NCT06108453
A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin on the Pharmacokinetics of Methotrexate in Elderly Subjects
Not yet reported Seoul National University Bundang Hospital 10 participants Est. completion 2024-11-24 1 site Stand-aloneOther conditions: Drug InteractionsView official trial listing → -
Completed NCT NCT06115824
New-diagnosed PCNSL Treated With Methotrexate (MTX) and Orelabrutinib-based Regimen
Huashan Hospital 136 participants Est. completion 2024-07-30 1 siteOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Status unknown NCT NCT06123403
Evaluation of High Dose Methotrexate Toxicity
Sohag University 100 participants Est. completion 2025-06Other conditions: Methotrexate ToxicityView official trial listing → -
Status unknown NCT NCT06150794
Methotrexate Alone vs Combination With Excimer Light in Nail Psoriasis
Not yet reported Assiut University 20 participants Est. completion 2025-03-01 1 siteOther conditions: Nail PsoriasisView official trial listing → -
Status unknown NCT NCT06154590
Anastrozole Adjuvant Trial - Study of Anastrozole Compared to NOLVADEX (Tamoxifen Citrate) for Adjuvant Treatment of Early Breast Cancer Clinical Studies), Adjunct Cytotoxic Chemotherapy and Malignant Joint Tumor
DR. DIANE CHISESI NFS. MD. PHD. 100 participants Est. completion 2026-09 1 siteOther conditions: Metastatic Breast Cancer, Tumor, Muscle Neoplasms, Chronic PainView official trial listing → -
Status unknown NCT NCT06165770
Cornual Pregnancy: Results of a Single-center Retrospective Experience and Systematic Review on Reproductive Outcomes
University of Palermo 17 participants Est. completion 2024-01Other conditions: Ectopic PregnancyView official trial listing → -
Completed NCT NCT06172361
Induction and Tapering Therapy With Tofacitinib and Glucocorticoid in Patients With Polymyalgia Rheumatica
Not yet reported Zhejiang University 104 participants Est. completion 2026-05-30 1 siteOther conditions: Polymyalgia RheumaticaView official trial listing → -
Active, not recruiting NCT NCT06175338
Study, Evaluating Pharmacokinetics, Pharmacodynamics, Immunogenicity and Safety Profiles of Rituximab Compared to MabThera® in Patients With Rheumatoid Arthritis
Not yet reported Mabscale, LLC 208 participants Est. completion 2025-04 12 sites Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Not yet recruiting NCT NCT06175702
Treatment Protocol for Newky Diagnosed Adult Ph Positive ALL
PETHEMA Foundation 150 participants Est. completion 2030-12-25Other conditions: Lymphoblastic Leukemia, Philadelphia-Positive ALL, Adult ALLView official trial listing → -
Completed NCT NCT06186219
Recapturing Immune Tolerance to Pegloticase for the Management of Tophaceous Gout
Not yet reported University of California, Los Angeles 2 participants Est. completion 2024-11-22 1 site Stand-aloneOther conditions: Tophaceous GoutView official trial listing → -
Completed NCT NCT06190457
Safety and Efficacy of Intrathecal Rituximab in 16 Children of Stage Ⅲ、ⅣNon-Hodgkin Lymphoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 16 participants Est. completion 2022-08-30Other conditions: Lymphoma, Non-Hodgkin, Child, OnlyView official trial listing → -
Enrolling by invitation NCT NCT06204614
Drug Screening Using IMD in Bladder Cancer
Not yet reported Brigham and Women's Hospital 18 participants Est. completion 2028-08-01 1 site Stand-aloneOther conditions: Muscle Invasive Bladder Urothelial CarcinomaView official trial listing → -
Withdrawn NCT NCT06210750
Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)
Not yet reported National Cancer Institute (NCI) Est. completion 2026-09-22 Stand-aloneOther conditions: T Acute Lymphoblastic Leukemia, T Lymphoblastic LymphomaView official trial listing → -
Status unknown NCT NCT06217224
Evaluation of Prophylactic Photobiomodulation Therapy in Patients With Osteosarcoma
Not yet reported Instituto Nacional de Cancer, Brazil 53 participants Est. completion 2025-07-30 1 site Stand-aloneOther conditions: Mucositis OralView official trial listing → -
Completed NCT NCT06229145
A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout
Not yet reported Amgen 306 participants Est. completion 2026-03-26 74 sites Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT06231745
Paroxetine Safety and Efficacy in Rheumatoid Arthritis
Not yet reported Mostafa Bahaa 100 participants Est. completion 2025-07-20 1 siteOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT06260904
Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planus
Not yet reported All India Institute of Medical Sciences, Bhubaneswar 64 participants Est. completion 2025-10-30 1 siteOther conditions: Oral Lichen PlanusView official trial listing → -
Status unknown NCT NCT06277635
Effect of Silymarin Against Methotrexate-induced Liver Injury in Rheumatic Diseases
Not yet reported Phramongkutklao College of Medicine and Hospital 72 participants Est. completion 2025-04 1 siteOther conditions: Rheumatoid Arthritis, Psoriatic Arthritis, PsoriasisView official trial listing → -
Enrolling by invitation NCT NCT06281184
A 30-month Follow-up of MERINO Participants to Evaluate Long-term Effects of Methotrexate in Erosive Hand OA.
Diakonhjemmet Hospital 108 participants Est. completion 2027-12-01 1 siteOsteoarthritisView official trial listing → -
Status unknown NCT NCT06289205
"Comparing Methotrexate Usage Techniques to Prevent Proliferative Vitreoretinopaty After Retinal Detachment Vitrectomy"
Not yet reported, Not yet reported University of Health Sciences Lahore 120 participants Est. completion 2025-05 1 site Stand-aloneOther conditions: Proliferative VitreoretinopathyView official trial listing → -
Withdrawn NCT NCT06290687
Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy
Not yet reported Case Comprehensive Cancer Center Est. completion 2027-12-29 Stand-aloneOther conditions: Malignant Neoplasm of Bladder, Muscle Invasive Bladder CarcinomaView official trial listing → -
Status unknown NCT NCT06300333
Treatment of Ectopic Pregnancy by Low Dose of Methotrexate
Assiut University 20 participants Est. completion 2025-03Other conditions: Ectopic PregnancyView official trial listing → -
Status unknown NCT NCT06362720
The Comparison the CMV Infection and Reactivation After Allogeneic Hematopoietic Stem Cell Transplantation Between Standard Regimen, Methotrexate Plus Cyclosporin A, and Post-transplant Cyclophosphamide-based Regimen
Siriraj Hospital 158 participants Est. completion 2024-12-31Other conditions: CMV Infection or Reactivation After Allogenic HSCTView official trial listing → -
Status unknown NCT NCT06370156
Evaluation of TWEAK in Plaque Psoriasis and Psoriatic Arthritis Patients
Egymedicalpedia 100 participants Est. completion 2025-06-10 1 siteOther conditions: Plaque PsoriasisView official trial listing → -
Completed NCT NCT06373744
Metronomic Chemotherapy in a Real-world Population of Advanced Breast Cancer Patients
Sun Yat-sen University 597 participants Est. completion 2024-01-01 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT06381518
Switching From Intravenous to Subcutaneous Infliximab in Adult Patients With Inflammatory Bowel Disease
Not yet reported Zuyderland Medisch Centrum 38 participants Est. completion 2025-12-01 1 siteOther conditions: IBD, Infliximab, Crohn Disease, Ulcerative ColitisView official trial listing → -
Completed NCT NCT06426979
Sequential Letrozole and Methotrexate Therapy Role in Treatment of Tubal Ectopic Pregnancy
Not yet reported Zagazig University 200 participants Est. completion 2024-01-01 1 siteOther conditions: Pregnancy TubalView official trial listing → -
Status unknown NCT NCT06445257
A Clinical Study Evaluating the Safety and Efficacy of ZRMT Regimen in the Treatment of PCNSL
Not yet reported Huai'an First People's Hospital 30 participants Est. completion 2026-04-30 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT06454266
First-line Treatment of PCNSL With the Combination of Orelabrutinib, Rituximab, and Methotrexate (ORM Regimen)
Not yet reported Ningbo No. 1 Hospital 22 participants Est. completion 2024-07-25 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Withdrawn NCT NCT06466798
Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS Malignancies
Not yet reported Jeffrey Treiber Est. completion 2027-07-01 Stand-aloneOther conditions: Recurrent Ependymoma, Recurrent Medulloblastoma, CNS MalignanciesView official trial listing → -
Completed NCT NCT06476366
Comparison of Efficacy of Methotrexate and Azathioprine in Patients With Chronic Actinic Dermatitis: A Randomized Controlled Trial
Not yet reported Pak Emirates Military Hospital 50 participants Est. completion 2025-12-28 1 siteOther conditions: Chronic Actinic DermatitisView official trial listing → -
Active, not recruiting NCT NCT06496178
A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients (LiGeR-HN2)
Not yet reported Merus B.V. 621 participants Est. completion 2029-03 194 sitesOther conditions: Head and Neck Squamous Cell CarcinomaView official trial listing → -
Completed NCT NCT06504082
Comparison of the Effectiveness of Single-Dose Methotrexate Protocol With Letrozole + Single-Dose Methotrexate in the Medical Treatment of Patients Diagnosed With Ectopic Pregnancy
Not yet reported Yuzuncu Yil University 60 participants Est. completion 2022-09-05 1 siteOther conditions: Ectopic PregnancyView official trial listing → -
Status unknown NCT NCT06512753
The Effectiveness of Hydroxychloroquine Versus Methotrexate in the Treatment of Lichen Planopilaris in Routine Clinical Care: a Patient Preference Trial
Erasmus Medical Center 56 participants Est. completion 2026-07-01 1 siteOther conditions: Lichen Planopilaris, Cicatricial AlopeciaView official trial listing → -
Completed NCT NCT06512766
a Retrospective Study on the Systemic Treatment of LPP and FFA
Erasmus Medical Center 315 participants Est. completion 2023-02-01 1 siteOther conditions: Cicatricial Alopecia, Lichen Planopilaris, Lichen Plano-Pilaris, Frontal Fibrosing Alopecia, Hair Diseases, Scarring Alopecia, Hair Loss/BaldnessView official trial listing → -
Status unknown NCT NCT06554470
Local vs Systemic Methotrexate in Management of Uterine Ectopic Pregnancy
Not yet reported Tanta University 34 participants Est. completion 2025-07-01 1 site Stand-aloneOther conditions: Local, Systemic, Methotrexate, Uterine Ectopic PregnancyView official trial listing → -
Completed NCT NCT06555497
Topical 1% Methotrexate Gel Versus Clobetasol Propionate in Patients With Psoriasis
Not yet reported Dr. Jose N. Rodriguez Memorial Hospital and Sanitarium 2 participants Est. completion 2023-12-31 1 site Stand-aloneOther conditions: Pilot Study, PsoriasisView official trial listing → -
Completed NCT NCT06565273
Study to Investigate the Efficacy, Safety, and Tolerability of FBL-MTX in Patients With Rheumatoid Arthritis
Not yet reported SOLFARCOS - Pharmaceutical and Cosmetic Solutions Ltd 40 participants Est. completion 2026-07-20 8 sitesOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT06574594
Effect of MTX Discontinuation on Shingrix Response in RA
Not yet reported Konkuk University Medical Center 110 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Terminated NCT NCT06578728
Local Methotrexate Injections for the Treatment of Nail Psoriasis
Not yet reported Weill Medical College of Cornell University 1 participants Est. completion 2026-06-05 1 site Stand-aloneOther conditions: Nail PsoriasisView official trial listing → -
Not yet recruiting NCT NCT06590090
Natrunix in Combination With Methotrexate for Rheumatoid Arthritis Treatment
Not yet reported XBiotech, Inc. 108 participants Est. completion 2027-07-15 Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Not yet recruiting NCT NCT06601595
Prevelance of Axial Spondylosis Arthritis in Inflammatory Bowel Disease and Its RESPONSE to Tumour Necrosis Factor (TNF) Inhibitors Treatment in Assiut University Hospital
Mohamed Nasr 100 participants Est. completion 2026-03Other conditions: Inflammatory Bowel Disease (IBD), Spondylarthropathies, TNF-alpha InhibitorsView official trial listing → -
Not yet recruiting NCT NCT06641128
The Possible Efficacy and Protective Effect of Empagliflozin in Rheumatoid Arthritis Patients Treated with Methotrexate
Not yet reported Tanta University 44 participants Est. completion 2025-04-10 1 siteOther conditions: Rheumatoid Arthritis (RA), Methotrexate Induced Nephrotoxicity, Methotrexate Adverse ReactionView official trial listing → -
Not yet recruiting NCT NCT06646211
High-dose Methotrexate Combined with Thiotepa and Zanubrutinib in the Treatment of Newly Diagnosed PCNSL (MTZ)
Not yet reported Sun Yat-sen University 30 participants Est. completion 2028-01-01 1 site Stand-aloneOther conditions: Primary Central Nervous System Lymphoma (PCNSL), Non Hodgkin Lymphoma (NHL)View official trial listing → -
Active, not recruiting NCT NCT06673134
Prospective Cohort Establishment and Clinical Observation of Children With Crohn's Disease
Tongji Hospital 100 participants Est. completion 2028-07-24 1 siteOther conditions: Crohn DiseaseView official trial listing → -
Status unknown NCT NCT06712238
Evaluation The Effect of NB-UVB and Methotrexate on The Level of Serum Gelsolin in Psoriatic Patients
Not yet reported Aswan University 48 participants Est. completion 2025-06-10 1 siteOther conditions: Psoriatic ConditionsView official trial listing → -
Not yet recruiting NCT NCT06719479
A Clinical Trial to Evaluate Effect of IAE0972 Combined with Chemotherapy for R/M HNSCC or NPC(Note: It is Currently Phase II.).
Not yet reported, Not yet reported SUNHO(China)BioPharmaceutical CO., Ltd. 60 participants Est. completion 2028-01-01 Stand-aloneOther conditions: NPC, HNSCC, Recurrence, MetastasisView official trial listing → -
Not yet recruiting NCT NCT06724952
Effect of Silymarin in Rheumatoid Arthritis Patients Treated With Methotrexate
Not yet reported Tanta University 44 participants Est. completion 2025-04-10 1 siteOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Not yet recruiting NCT NCT06739551
Systemic Treatment Options for Generalized Lichen Planus
Not yet reported Sheikh Zayed Medical College 124 participants Est. completion 2025-03-20 1 siteOther conditions: Lichen PlanusView official trial listing → -
Not yet recruiting NCT NCT06741813
Allo-HSCT vs ASCT in Adult T-LBL
Not yet reported Peking University People's Hospital 230 participants Est. completion 2029-12-31 Stand-aloneOther conditions: T Lymphoblastic LymphomaView official trial listing → -
Enrolling by invitation NCT NCT06773936
Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia
Not yet reported SWOG Cancer Research Network 55 participants Est. completion 2033-07 16 sitesOther conditions: Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia, CD19+ Acute LeukemiaView official trial listing → -
Not yet recruiting NCT NCT06861348
Effectiveness and Safety of InO±DLI for Relapsed B-ALL/LBL After Allo-HSCT
Not yet reported First Affiliated Hospital of Zhejiang University 23 participants Est. completion 2027-04-30 1 site Stand-aloneOther conditions: Leukemia, Lymphocytic, AcuteView official trial listing → -
Not yet recruiting NCT NCT06872073
Assessment of Methotreaxate-induced Liver Fibrosis by Transient Elastography and Serological Markers
Assiut University 144 participants Est. completion 2027-05-01Other conditions: Liver FibrosisView official trial listing → -
Not yet recruiting NCT NCT06877455
Topical Methotrexate with Fractional CO2 Laser in Treatment of Non Segmental Vitiligo
Not yet reported Assiut University 50 participants Est. completion 2026-12-30 Stand-aloneOther conditions: VitiligoView official trial listing → -
Not yet recruiting NCT NCT06895278
Articular Damage in Patients With Juvenile Idiopathic Arthritis After Transition to Adult Care
IRCCS Burlo Garofolo 100 participants Est. completion 2025-12-31 3 sitesOther conditions: Juvenile Chronic ArthritisView official trial listing → -
Not yet recruiting NCT NCT06901999
Methotrexate or Thiotepa Combined With R-CHOP and Orelabrutinib in CNSL Patients
Not yet reported Ruijin Hospital 23 participants Est. completion 2028-11 Stand-aloneOther conditions: CNS LymphomaView official trial listing → -
Not yet recruiting NCT NCT06918886
Comparison of Liver Health in Psoriatic Arthritis Patients Using Anti-TNF or Anti-IL17 Treatments
Bezmialem Vakif University 90 participants Est. completion 2025-05-01 1 siteOther conditions: Psoriatic Arthritis (PsA), Liver Fibrosis, Liver DiseasesView official trial listing → -
Not yet recruiting NCT NCT06930105
Impact of Low-intensity Chemotherapy Combined With Short-course Blinatumomab on Allo-HSCT in Adults With Ph- B-ALL
Not yet reported Xianmin Song, MD 45 participants Est. completion 2028-05-01 Stand-aloneOther conditions: Acute Lymphoid Leukemia (ALL)View official trial listing → -
Not yet recruiting NCT NCT06943482
Comparing Effectiveness of Steroids and Methotrexate in Treatment of Chronic Inflammatory Breast Disease
Not yet reported National University Hospital, Singapore 40 participants Est. completion 2028-02-01 1 site Stand-aloneOther conditions: Idiopathic Granulomatous MastitisView official trial listing → -
Not yet recruiting NCT NCT06949267
A Study of iMSC for the Prevention of Acute Graft-versus-host Disease After Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported Ruijin Hospital 56 participants Est. completion 2028-03-31 Stand-aloneOther conditions: Acute Graft-versus-Host DiseaseView official trial listing → -
Completed NCT NCT06951282
Impact of Selenium on Methotrexate Induced Spermatotoxicity; A Comparative Study
Not yet reported, Not yet reported Ain Shams University 40 participants Est. completion 2024-12-31 1 siteOther conditions: Methotrexate SpermatotoxicityView official trial listing → -
Not yet recruiting NCT NCT06965244
Lenalidomide vs Methotrexate in Difficult-to-treat Cutaneous Lupus Erythematosus
Not yet reported Assistance Publique - Hôpitaux de Paris 122 participants Est. completion 2029-04-01Other conditions: Cutaneous Lupus Erythematosus (CLE)View official trial listing → -
Active, not recruiting NCT NCT07008846
Efficacy of Tofacitinib, Methotrexate Combination Therapy Versus Upadacitinib, Methotrexate Combination Therapy in Moderate to Severe Rheumatoid Arthritis
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 96 participants Est. completion 2026-09-30 1 site Stand-aloneOther conditions: Moderate to Severe Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT07058337
Methotrexate in Retinal Detachment With Proliferative Vitreoretinopathy
Not yet reported Benha University 20 participants Est. completion 2025-06-09 1 siteOther conditions: Retinal DetachmentView official trial listing → -
Not yet recruiting NCT NCT07072585
Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)
Not yet reported, Not yet reported Children's Oncology Group 1708 participants Est. completion 2035-09-01 Stand-aloneOther conditions: Stage II T Lymphoblastic Leukemia/Lymphoma, Stage III T Lymphoblastic Leukemia/Lymphoma, Stage IV T Lymphoblastic Leukemia/Lymphoma, T Acute Lymphoblastic Leukemia, T Lymphoblastic LymphomaView official trial listing → -
Active, not recruiting NCT NCT07080125
A Study Using a Disease Registry to Observe the Long-term Effects of Nintedanib in People With Scleroderma-related Lung Fibrosis
Boehringer Ingelheim 2000 participants Est. completion 2033-12-31 1 siteOther conditions: Interstitial Lung Diseases, Systemic Sclerosis Associated Interstitial Lung DiseaseView official trial listing → -
Completed NCT NCT07094880
Subcuteous Methotrexate in Rheumatoid Arthritis
Not yet reported Bangladesh Medical University 45 participants Est. completion 2016-06-01Other conditions: Methotrexate Adverse Reaction, Advantage of Using Subcutaneous Route for MethotrexateView official trial listing → -
Not yet recruiting NCT NCT07142863
Envafolimab Combined With Neoadjuvant Chemotherapy Treat Stage IIb Resectable Osteosarcoma Patients
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 23 participants Est. completion 2026-09-30 1 site Stand-aloneObstructive sleep apnea Other conditions: Neoadjuvant Therapy, Neoadjuvant Chemotherapy, PD-L1 Antibody, EnvafolimabView official trial listing → -
Not yet recruiting NCT NCT07156604
Vebreltinib for Neoadjuvant in METex 14 Skipping Mutant Stage IIA-IIIB (N2) Non-small Cell Lung Cancer (NSCLC)
Not yet reported Fudan University 30 participants Est. completion 2030-09-30 1 siteOther conditions: NSCLC, Neoadjuvant TherapyView official trial listing → -
Not yet recruiting NCT NCT07157514
Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML
Not yet reported, Not yet reported Actinium Pharmaceuticals 306 participants Est. completion 2034-02 Stand-aloneOther conditions: Acute Leukemia, Myeloid Leukemia, Acute Myelogenous Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia, in Relapse, Myelogenous Leukemia, Myelogenous Leukemia, Acute, Myelogenous Leukemia in Relapse, Transplant-Related Disorder, Allogeneic Disease, Refractory AMLView official trial listing → -
Not yet recruiting NCT NCT07175415
HEM-iSMART E: Capivasertib + Venetoclax + Dexamethasone in Pediatric Patients With Relapsed or Refractory Hematological Malignancies
Not yet reported, Not yet reported Princess Maxima Center for Pediatric Oncology 42 participants Est. completion 2032-10-01 Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent, Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) RefractoryView official trial listing → -
Active, not recruiting NCT NCT07176390
A Clinical Study of Tulisokibart (MK-7240) to Treat Rheumatoid Arthritis (RA) (MK-7240-014)
Not yet reported Merck Sharp & Dohme LLC 185 participants Est. completion 2029-03-01 61 sites Stand-aloneOther conditions: Arthritis, RheumatoidView official trial listing → -
Not yet recruiting NCT NCT07190534
The Effectiveness of Hydroxychloroquine Versus Methotrexate in the Treatment of Frontal Fibrosing Alopecia in Routine Clinical Care: a Patient Preference Trial (FFA Trial)
Erasmus Medical Center 50 participants Est. completion 2027-05 1 siteOther conditions: Frontal Fibrosing Alopecia, Cicatricial AlopeciaView official trial listing → -
Active, not recruiting NCT NCT07196449
Drug-Drug Interaction of Rifampicin and Cyclosporine on Methotrexate Pharmacokinetics in Healthy Subjects
Not yet reported Seoul National University Bundang Hospital 12 participants Est. completion 2026-04-14 1 site Stand-aloneOther conditions: Drug Drug Interaction (DDI)View official trial listing → -
Not yet recruiting NCT NCT07208890
Methotrexate Iontophoresis Versus Methotrexate 1% Gel on Depigmentation in Vitiligo Patients
Not yet reported Pharos University in Alexandria 30 participants Est. completion 2026-03-10 Stand-aloneOther conditions: Vitiligo - Evaluation of Methotrexate Iontophoresis and Topical Methotrexate Gel as Localized Treatment ApproacheView official trial listing → -
Not yet recruiting NCT NCT07288307
Surgical Evacuation Versus Methotrexate Injection in Treatment of Caesarean Scar Pregnancy [Clinical Trial ]
Not yet reported Minia University 42 participants Est. completion 2027-02-01 Stand-aloneOther conditions: Caesarean Scar PregnancyView official trial listing → -
Not yet recruiting NCT NCT07291102
Comparison of Neurocognitive Outcome in Two Standard Regimen for Treatment of Low-risk Medulloblastoma
Not yet reported Nationwide Children's Hospital 96 participants Est. completion 2038-10 2 sites Stand-aloneOther conditions: MedulloblastomaView official trial listing → -
Not yet recruiting NCT NCT07301138
BEBT-908 Plus Chemotherapy Treatment for CR MRD-Positive MEF2D-Rearranged and Pre-B Acute Lymphoblastic Leukemia Patients
Not yet reported Ruijin Hospital 23 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07319793
Pre-DLI or Pro-DLI in Relapsed/Refractory Myeloid Neoplasms After HSCT
Not yet reported Peking University People's Hospital 200 participants Est. completion 2028-06-30 Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes (MDS)View official trial listing → -
Not yet recruiting NCT NCT07327476
Effect of Oral Ice Chips to Prevent Chemotherapy-Induced Oral Mucositis in Patient With Solid Tumor Treated With 5 Fluorouracil and Methotrexate
Not yet reported University of Health Sciences Lahore 102 participants Est. completion 2026-11-30 1 siteOther conditions: Chemotherapy Induced Oral MucositisView official trial listing → -
Not yet recruiting NCT NCT07336641
LANDSCAPE: Demographics and Treatment Patterns of Patients With Immune-Mediated Inflammatory Skin Diseases in Italian Clinical Practice
Fondazione ISIDE 20000 participants Est. completion 2028-01 1 siteOther conditions: Psoriasis, Atopic Dermatitis, Vitiligo, Alopecia Areata, Hidradenitis SuppurativaView official trial listing → -
Active, not recruiting NCT NCT07338305
Methotrexat to Hand Eczema in the BIOSKIN Cohort
Lone Skov 50 participants Est. completion 2026-12 1 siteOther conditions: Atopic Dermatitis, Contact Dermatitis, Hand EczemaView official trial listing → -
Completed NCT NCT07352293
The Value of Methotrexate in NCES for Stable Vitiligo
Not yet reported Cairo University 21 participants Est. completion 2026-09-21 1 siteOther conditions: VitiligoView official trial listing → -
Not yet recruiting NCT NCT07352566
Utilization of a Microdevice for Psoriasis and Atopic Dermatitis
Not yet reported University of California, San Francisco 10 participants Est. completion 2030-06-01 1 site Stand-aloneOther conditions: Psoriasis, Atopic DermatitisView official trial listing → -
Not yet recruiting NCT NCT07357649
Baricitinib Effects on Procoagulant State in Rheumatoid Arthritis
Not yet reported Tanta University 100 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT07360340
Methotrexate Therapy and High-Resolution CT Chest and Spirometry Test Findings in Patients With Rheumatoid Arthritis.
Ain Shams University 50 participants Est. completion 2023-07-31 1 siteOther conditions: Methohexitone Pulmonary Adverse ReactionView official trial listing → -
Not yet recruiting NCT NCT07361133
Cyclophosphamide and Etoposide as a Metronomic Therapy in Advanced Head and Neck Squamous Cell Cancer
Not yet reported National Cancer Institute, Egypt 120 participants Est. completion 2026-09 1 siteOther conditions: Squamous Cell Carcinoma, Advanced Head and Neck CancerView official trial listing → -
Enrolling by invitation NCT NCT07386587
Methotrexate Alone vs Methotrexate + Etanercept for Minimal/Low Disease Activity in Juvenile Idiopathic Arthritis
Not yet reported University of Child Health Sciences and Children's Hospital, Lahore 60 participants Est. completion 2026-07-27 1 site Stand-aloneOther conditions: Juvenile Idiopathic ArthritisView official trial listing → -
Not yet recruiting NCT NCT07398651
Apremilast and Adalimumab in Psoriatic Arthritis Patients
Not yet reported Tanta University 60 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: Psoriatic Arthritis, Ultrasound Assessment, TNFView official trial listing → -
Not yet recruiting NCT NCT07406204
Tofacitinib vs Methotrexate for Severe Alopecia Areata (TOFA-MTX-AA)
Not yet reported Hayat Abad Medical Complex, Peshawar 78 participants Est. completion 2026-08-15Other conditions: Alopecia Areata, Alopecia Totalis (AT), Alopecia UniversalisView official trial listing → -
Not yet recruiting NCT NCT07406230
Methotrexate Early Toxicity Monitoring
Not yet reported Assistance Publique Hopitaux De Marseille 50 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT07428551
Comparative Study of Leflunomide Plus Methotrexate Versus Methotrexate Monotherapy in Refractory Polyarticular Juvenile Idiopathic Arthritis Patients
Not yet reported Bangladesh Medical University 50 participants Est. completion 2026-01-28 1 site Stand-aloneOther conditions: Juvenile Idiopathic Arthritis, Polyarticular Juvenile Idiopathic Arthritis, Refractory Polyarticular Juvenile Idiopathic ArthritisView official trial listing → -
Not yet recruiting NCT NCT07432386
Methotrexate Versus Apremilast for Pruritus in Psoriasis
Not yet reported Zarmeen Khawar 80 participants Est. completion 2026-10-14 1 site Stand-aloneOther conditions: Psoriasis, PruritusView official trial listing → -
Completed NCT NCT07432815
Treatment of Psoriasis With Depression and/or Anxiety With Methotrexate vs Combined Methotrexate and Antidepressant
Not yet reported Cairo University 40 participants Est. completion 2026-06-14 1 site Stand-aloneOther conditions: Depression, Anxiety, PsoriasisView official trial listing → -
Not yet recruiting NCT NCT07443592
Treatment for Ph-negative ALL for Adults up to 65 Years
Not yet reported PETHEMA Foundation 330 participants Est. completion 2033-06-01 95 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT07459335
TArget Trial Emulation Comparing Effectiveness of Tocilizumab vs Methotrexate In Corticosteroid-Treated GCA Patients
Groupe français d'étude des Maladies Inflammatoires de loeil 1667 participants Est. completion 2024-12-31 2 sitesCardiovascular disease Other conditions: Giant Cell Arteritis (GCA)View official trial listing → -
Not yet recruiting NCT NCT07459933
Topical Methotrexate vs Minoxidil for Localized Alopecia Areata
Not yet reported Jinnah Postgraduate Medical Centre 268 participants Est. completion 2026-09-15 Stand-aloneOther conditions: Alopecia AreataView official trial listing → -
Completed NCT NCT07472166
Efficacy of Tofacitinib on Skin Thickening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With Methotrexate
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 34 participants Est. completion 2025-08-30 1 siteOther conditions: Scleroderma, SystemicView official trial listing → -
Not yet recruiting NCT NCT07497282
Venlafaxine as Adjunct Therapy in Rheumatoid Arthritis
Not yet reported Ain Shams University 70 participants Est. completion 2026-12-26Other conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT07498465
A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia
Not yet reported Children's Oncology Group Est. completion 2028-11-12 Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia, Childhood Mixed Phenotype Acute Leukemia, Mixed Phenotype Acute LeukemiaView official trial listing → -
Completed NCT NCT07512401
Methotrexate Monitoring Target Trial Emulation
Mayo Clinic 2414 participants Est. completion 2025-12-31Other conditions: Rheumatic DiseasesView official trial listing → -
Not yet recruiting NCT NCT07543640
EFFICACY OF ROFLUMILAST IN THE TREATMENT OF FLEXURAL AND/OR GENITAL PSORIASIS: A RANDOMIZED CONTROLLED TRIAL.
Not yet reported Eman Raafat Said 56 participants Est. completion 2026-08Other conditions: Flexural Psoriasis (Also Known as Inverse or Intertriginous Psoriasis) and Genital PsoriasisView official trial listing → -
Not yet recruiting NCT NCT07557095
Serum Level of IL-33 in Egyptian Psoriatic Patients
scientific_committee 118 participants Est. completion 2027-03-01Other conditions: Egyptian Psoriatic PatientsView official trial listing → -
Not yet recruiting NCT NCT07562568
SHR2554/AZA + Overlapped TBF for High-risk/Relapsed Leukemia/MDS
Not yet reported The First Affiliated Hospital of Soochow University 160 participants Est. completion 2030-06 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, MDS, Transplantation, Stem Cell, Conditioning Therapy, SHR2554, AzacytidineView official trial listing → -
Not yet recruiting NCT NCT07581418
Comparison of Methotrexate and Tofacitinib in Chronic Plaque Psoriasis
Not yet reported Pak Emirates Military Hospital 88 participants Est. completion 2026-12-01Other conditions: Chronic Plaque PsoriasisView official trial listing → -
Not yet recruiting NCT NCT07614022
A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL)
Not yet reported Wake Forest University Health Sciences 26 participants Est. completion 2030-03 2 sites Stand-aloneOther conditions: Philadelphia Positive Acute Lymphoblastic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07624903
Letrozole Versus Methotrexate for Management of Undisturbed Ectopic Pregnancy
Not yet reported Kafrelsheikh University 70 participants Est. completion 2027-07 1 siteOther conditions: Ectopic PregnancyView official trial listing → -
Not yet recruiting NCT NCT07636057
Comparison of Effectiveness and Safety of Tofacitinib Versus Upadacitinib as Add-on to Methotrexate in Rheumatoid Arthritis
Not yet reported Sheikh Zayed Federal Postgraduate Medical Institute 100 participants Est. completion 2027-05-10 Stand-aloneOther conditions: Rheumatoid Arthritis (RA)View official trial listing → -
Not yet recruiting NCT NCT07636564
Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More Treatment
Not yet reported SWOG Cancer Research Network 90 participants Est. completion 2032-04-16 Stand-aloneOther conditions: Acute Leukemia of Ambiguous Lineage, B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, T Acute Lymphoblastic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07643038
Treatment Strategy for Patients With RA-ILD
Not yet reported Chinese SLE Treatment And Research Group 204 participants Est. completion 2029-07-31 22 sitesOther conditions: Rheumatoid Arthritis Associated Interstitial Lung DiseaseView official trial listing → -
Not yet recruiting NCT NCT07643103
Immuno-Targeted Therapy Plus Low-Dose Chemotherapy for Newly Diagnosed Adult Ph-Negative B-ALL: A Prospective Umbrella Trial
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 32 participants Est. completion 2030-05-31 Stand-aloneOther conditions: Ph- Acute Lymphoblastic Leukemia (Ph-ALL)View official trial listing → -
Completed NCT NCT07662265
Tocilizumab in Refractory ASS-ILD
Hu Yinan 111 participants Est. completion 2025-10-31 1 siteOther conditions: Antisynthetase Syndrome, TocilizumabView official trial listing → -
Not yet recruiting NCT NCT07677813
Orelabrutinib Combined With Induction Therapy Followed by Sequential Monotherapy Maintenance in MCD Subtype Diffuse Large B-cell Lymphoma
Not yet reported Ou Bai, MD/PHD 66 participants Est. completion 2031-12-31 1 site Stand-aloneOther conditions: DLBCL - Diffuse Large B Cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT07686107
Trial of Revumenib Plus FLA Chemotherapy for Children With Relapsed or Refractory NUP98-rearranged AML."
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 24 participants Est. completion 2030-12-31 Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Not yet recruiting NCT NCT07724457
Testing the Addition of a New Anti-Cancer Drug, Glofitamab to Usual Chemotherapy for Burkitt and Double Hit Lymphoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 271 participants Est. completion 2033-11-01 Stand-aloneOther conditions: Recurrent Burkitt Lymphoma, Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 Rearrangements, Refractory Burkitt Lymphoma, Refractory High Grade B-Cell Lymphoma With MYC and BCL2 RearrangementsView official trial listing → -
Not yet recruiting NCT NCT07758621
SYS6010 vs Investigator's Choice of Monotherapy in Patients With Recurrent or Metastatic HNSCC
Not yet reported CSPC Megalith Biopharmaceutical Co.,Ltd. 340 participants Est. completion 2028-12-01Other conditions: Head and Neck Squamous Cell CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07764601
R-MA-PD-1 Versus R-MA in Treatment-naive Primary CNS Lymphoma
Not yet reported WEI XU 58 participants Est. completion 2029-08 5 sites Stand-aloneOther conditions: Primary Central Nervous System Lymphoma, Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT07806357
Prednisolone Monotherapy Versus Prednisolone Plus Methotrexate in ENL
Not yet reported Chittagong Medical College 19 participants Est. completion 2019-12-31 1 site Stand-aloneOther conditions: LeprosyView official trial listing → -
Not yet recruiting NCT NCT07812493
Pirtobrutinib Plus Methotrexate-Based Chemoimmunotherapy for Systemic DLBCL With CNS Involvement
Not yet reported Pengpeng Xu 24 participants Est. completion 2030-09-01 1 siteOther conditions: Pirtobrutinib, Immunochemotherapy, DLBCL - Diffuse Large B Cell Lymphoma, CNS Involvement of Systemic LymphomaView official trial listing → -
Active, not recruiting NCT NCT07842796
Sequential vs. Combined Letrozole and Methotrexate for Tubal Ectopic Pregnancy.
Not yet reported, Not yet reported Benha University 144 participants Est. completion 2026-12-12 1 siteOther conditions: Ectopic PregnancyView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Methotrexate Sodium, METHOTREXATE, Methotrexate (MTX)
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