GLP-1 Market
LLY $1138.28 ▲ +2.0% NVO $43.45 ▲ +0.9% PFE $27.72 • 0.0% VKTX $31.53 ▼ -1.4% KLRA $13.75 ▼ -1.4% GPCR $38.44 ▼ -0.6% RHHBY $54.80 ▲ +3.9%
Market data delayed up to 20 min · Source: Twelve Data

Empowering you to have better conversations with your doctor.

Subscribe
About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Metformin Hydrochloride

Company
VA Office of Research and Development
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
19 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

19 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Sep 15, 2026

Find a Clinical Trial Near Me

See recruiting studies for Metformin Hydrochloride and check eligibility with the study team.

Select conditions
Match
Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT03424005

    A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

    Not yet reported, Not yet reported Hoffmann-La Roche 1132 participants Est. completion 2030-09-30 53 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT03568630

    Blood Markers of Early Pancreas Cancer

    University of Nebraska 1250 participants Est. completion 2028-07 1 site
    Type 2 diabetesPrediabetes Other conditions: Pancreas Cyst, Chronic Pancreatitis, Genetic Predisposition to Disease, Inherited Disease
    View official trial listing →
  • Recruiting NCT NCT03675893

    RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial Cancer

    Not yet reported Dana-Farber Cancer Institute 110 participants Est. completion 2031-08-01 3 sites
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Recruiting NCT NCT04114136

    Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

    Not yet reported Dan Zandberg 72 participants Est. completion 2032-04-30 1 site
    Obstructive sleep apnea Other conditions: Melanoma, NSCLC, Hepatocellular Carcinoma, Urothelial Cancer, Gastric Adenocarcinoma, HNSCC, Esophageal Adenocarcinoma
    View official trial listing →
  • Recruiting NCT NCT04670666

    Efficacy and Safety of Madalena Association in the Treatment of Type II Diabetes Mellitus

    Not yet reported EMS 270 participants Est. completion 2027-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT05041907

    Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)

    Not yet reported University of Oxford 3800 participants Est. completion 2027-01 7 sites
    Other conditions: COVID-19
    View official trial listing →
  • Recruiting NCT NCT05132439

    MetfOrmin BenefIts Lower Extremities With Intermittent Claudication

    Not yet reported VA Office of Research and Development 200 participants Est. completion 2032-02-28 1 site
    Alcohol use disorder
    View official trial listing →
  • Recruiting NCT NCT05316935

    GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients

    Not yet reported, Not yet reported Xiaojun Chen 80 participants Est. completion 2028-03-30 2 sites
    Other conditions: Endometrial Neoplasms, Atypical Endometrial Hyperplasia, Progesterone Resistance
    View official trial listing →
  • Recruiting NCT NCT05345327

    SGLT2 Inhibitors As First Line Therapy to Prevent Renal Decline in Type 2 Diabetes

    Not yet reported The George Institute 994 participants Est. completion 2026-06-30 8 sites
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT05414409

    The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

    Not yet reported Heba M. Ismail 114 participants Est. completion 2027-03-01 1 site
    Other conditions: Type 1 Diabetes, Obesity
    View official trial listing →
  • Recruiting NCT NCT06185179

    Metformin and Muscle Recovery

    Not yet reported University of Utah 50 participants Est. completion 2030-05-31 1 site
    Other conditions: Muscle Atrophy or Weakness
    View official trial listing →
  • Recruiting NCT NCT06862739

    Glycemic Control With Triple Pathway Approach Through Empagliflozin, Linagliptin and Metformin Combination

    Not yet reported Nabiqasim Industries (Pvt) Ltd 800 participants Est. completion 2026-06-30 2 sites
    Other conditions: Diabetes Mellitus, Type 2 DM
    View official trial listing →
  • Recruiting NCT NCT06896981

    Semaglutide in Women With Polycystic Ovary Syndrome and Obesity

    Not yet reported, Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 30 participants Est. completion 2025-12-31 1 site
    Other conditions: Polycystic Ovary Syndrome (PCOS) Women, Obesity
    View official trial listing →
  • Recruiting NCT NCT07064486

    A Study of BGM0504 in Participants With Type 2 Diabetes in Indonesia

    Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 477 participants Est. completion 2026-07-31 4 sites
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07065591

    Anti-Diabetic Drug, Exercise and Healthy Diet for Knee Osteoarthritis With Overweight/Obesity

    Not yet reported The University of Hong Kong 100 participants Est. completion 2028-07-17 1 site
    Osteoarthritis
    View official trial listing →
  • Recruiting NCT NCT07297290

    Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)

    Not yet reported University Of Nigeria Teaching Hospital 220 participants Est. completion 2027-09-30 2 sites
    Other conditions: Obesity and Cardiovascular Risk, Insulin Resistance, Obesity (Body Mass Index >30 kg/m2)
    View official trial listing →
  • Recruiting NCT NCT07339722

    A Study of LY4515100 in Healthy Participants

    Not yet reported Eli Lilly and Company 123 participants Est. completion 2027-03 1 site
    Other conditions: Healthy
    View official trial listing →
  • Recruiting NCT NCT07366944

    PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes

    Not yet reported Cairo University 40 participants Est. completion 2026-06-05 1 site
    Other conditions: Polycystic Ovary Syndrome, Dry Eye, Obesity
    View official trial listing →
  • Recruiting NCT NCT07654179

    Metformin as Adjunct Therapy in Depression-obesity Comorbidity: Clinical and Genetic Evaluation

    Not yet reported Riphah International University 200 participants Est. completion 2027-06-11 2 sites
    Other conditions: Depression, Depressive Disorder, Overweight or Obesity, Depressive Symptoms
    View official trial listing →
  • Completed NCT NCT00004992

    Diabetes Prevention Program

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 3234 participants Est. completion 2001-04 1 site
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent, Glucose Intolerance
    View official trial listing →
  • Completed NCT NCT00068861

    Treatment of Infertility in Women With Polycystic Ovary Syndrome

    Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 678 participants Est. completion 2006-02 11 sites
    Other conditions: Polycystic Ovary Syndrome, Infertility, Pregnancy
    View official trial listing →
  • Completed NCT NCT00097500

    Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 69 participants Est. completion 2009-12 3 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00099320

    Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Thiazolidinediones or Thiazolidinediones and Metformin

    Not yet reported AstraZeneca 182 participants Est. completion 2005-08 51 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00099892

    Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 544 participants Est. completion 2005-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00102466

    Vildagliptin Compared to Gliclazide in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 1007 participants Est. completion 2009-01 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00111631

    A Study of DPP-IV Inhibitor in Patients With Type 2 Diabetes

    Not yet reported Hoffmann-La Roche 218 participants Est. completion 2006-10 37 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00162240

    PPAR - Combination With Metformin

    Not yet reported Bristol-Myers Squibb 534 participants Est. completion 2004-05 203 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT00182494

    Diabetes Prevention Program in Schizophrenia [DPPS]

    Not yet reported Hamilton Health Sciences Corporation 200 participants Est. completion 2009-01 1 site
    Other conditions: Diabetes Mellitus, Schizophrenia
    View official trial listing →
  • Completed NCT NCT00184626

    Comparison of Insulin Glargine Versus Biphasic Insulin Aspart 30/70 or Biphasic Insulin Aspart 30/70 in Combination With Metformin in Subjects With Type 2 Diabetes.

    Not yet reported Novo Nordisk A/S 97 participants Est. completion 2005-10-24 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT00209482

    Glaser Obesity Study

    Not yet reported, Not yet reported Glaser Pediatric Research Network 76 participants Est. completion 2007-11 5 sites
    Other conditions: Obesity
    View official trial listing →
  • Terminated NCT NCT00214591

    GALLANT 5 Tesaglitazar Versus Metformin

    Not yet reported AstraZeneca 580 participants Est. completion 2006-12 130 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00231647

    A Study on Efficacy and Safety of Topiramate OROS Controlled-Release in Obese, Type 2 Diabetic Subjects Managed With Diet or Metformin

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 113 participants Est. completion 2004-10
    Type 2 diabetes Other conditions: Obesity, Diabetes Mellitus, Adult-Onset
    View official trial listing →
  • Terminated NCT NCT00251953

    GALLANT 8 Tesaglitazar Add-on to Metformin

    Not yet reported AstraZeneca 555 participants Est. completion 2006-03 107 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00318461

    To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together

    Not yet reported Novo Nordisk A/S 1091 participants Est. completion 2008-11 190 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00324363

    Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Metformin or Sulfonylureas and Metformin

    Not yet reported AstraZeneca 466 participants Est. completion 2007-04 14 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00343395

    Rosiglitazone and Metformin: Outcomes Trial in Nondiabetic Patients With Stable Coronary Syndromes (Romance) Pilot Study

    Not yet reported Intermountain Health Care, Inc. 200 participants Est. completion 2008-01 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00349128

    Fenofibrate in Dyslipidemia and Metformin-Controlled Diabetes

    Not yet reported, Not yet reported Solvay Pharmaceuticals 382 participants 51 sites
    Other conditions: Dyslipidemia/Glucose Metabolism Disorder
    View official trial listing →
  • Completed NCT NCT00353691

    Glimepiride vs Metformin as Monotherapy in Pediatric Subjects With Type 2 Diabetes Mellitus

    Not yet reported Sanofi 100 participants Est. completion 2004-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00386100

    A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin

    Not yet reported GlaxoSmithKline 688 participants Est. completion 2009-09 116 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00399204

    Comparison of Cardiovascular Outcomes of Pioglitazone and Metformin in Type 2 Diabetes Patients

    Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh Est. completion 2012-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00400231

    The Fenofibrate and Metformin for Atherogenic Dyslipidemia (FAMA) Study

    Not yet reported University of Pennsylvania 124 participants Est. completion 2008-03 1 site
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT00413179

    The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women

    Not yet reported 59th Medical Wing 56 participants Est. completion 2003-04 1 site
    Other conditions: Polycystic Ovary Syndrome, Anovulation, Oligoovulation, Infertility, Hyperandrogenism
    View official trial listing →
  • Completed NCT NCT00428311

    Effects of Metformin vs Oral Contraceptives on CV Risk Markers in PCOS

    Not yet reported Hospital Universitario Ramon y Cajal 50 participants Est. completion 2006-10 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00437333

    Metformin Suspension and Insulin Sensitivity

    Not yet reported University Magna Graecia 30 participants Est. completion 2006-04 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00463502

    The Effect of Metformin Treatment on Thyroid Hormone Metabolism in Euthyroid Patients With Type 2 Diabetes Mellitus

    Not yet reported Haydarpasa Numune State Hospital
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00471523

    Treatment of Anovulatory Infertility in PCOS Patients

    Not yet reported University Magna Graecia 80 participants Est. completion 2007-03 1 site
    Other conditions: Infertility, Polycystic Ovary Syndrome, Anovulation
    View official trial listing →
  • Completed NCT NCT00502710

    A Study of Dipeptidyl-peptidase IV (DPP-IV) RO4876904 in Patients With Type 2 Diabetes.

    Not yet reported Hoffmann-La Roche 289 participants Est. completion 2008-04 48 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00506194

    Short-Term Intensive Insulin Therapy Induction of Long-term Glycemic Control

    Not yet reported Taipei Veterans General Hospital, Taiwan 60 participants Est. completion 2011-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00536211

    Physical Inactivity and Insulin Resistance in Skeletal Muscle.

    Not yet reported University of Kansas Medical Center Est. completion 2011-12 1 site
    Metabolic syndrome Other conditions: Insulin Resistance, Hypertension, Hypercholesterolemia, Obesity
    View official trial listing →
  • Withdrawn NCT NCT00541567

    BMS-646256 in Obese and Overweight Type 2 Diabetics

    Not yet reported, Not yet reported Solvay Pharmaceuticals 600 participants Est. completion 2010-06
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00546741

    Drug Interaction With Metformin

    Not yet reported AstraZeneca 18 participants Est. completion 2008-02 1 site
    Other conditions: Healthy Male and Female Subjects
    View official trial listing →
  • Completed NCT NCT00560690

    The Effect of Adding Metformin to the Treatment of Hepatitis C

    Not yet reported Tehran University of Medical Sciences 140 participants Est. completion 2010-12 1 site
    Other conditions: Hepatitis C
    View official trial listing →
  • Completed NCT NCT00622284

    Efficacy and Safety of BI 1356 in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 1560 participants 221 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00648505

    Food Study of Glipizide and Metformin HCl Tablets 5 mg/500 mg to Metaglip® Tablets 5 mg/500 mg

    Not yet reported Mylan Pharmaceuticals Inc 36 participants Est. completion 2005-06 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00666458

    18-week add-on to Metformin Comparison of Saxagliptin and Sitagliptin in Adult Patients With Type 2 Diabetes (T2D)

    Not yet reported AstraZeneca 822 participants Est. completion 2009-03 87 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00667498

    Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance

    Not yet reported Yale University 28 participants Est. completion 2007-12 1 site
    Other conditions: Pediatric Obesity, Insulin Resistance, Hyperinsulinemia
    View official trial listing →
  • Completed NCT NCT00669864

    Effect of Biphasic Insulin Aspart 30 Combined With Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin

    Not yet reported Novo Nordisk A/S 293 participants Est. completion 2009-04 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00670800

    Study of Brain Function in Women With Insulin Resistant Polycystic Ovary Syndrome

    Not yet reported University of Michigan 14 participants Est. completion 2009-08 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00679939

    Study In Postmenopausal Women With Type 2 Diabetes Looking At Approved Diabetes Drugs And How They Affect Bone Health

    Not yet reported GlaxoSmithKline 226 participants Est. completion 2010-09-16 42 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00683657

    Safety and Efficacy Study of Subjects That Are Taking Saxagliptin Added Onto Metformin XR Compared to Subjects Taking Metformin XR Alone

    Not yet reported AstraZeneca 93 participants Est. completion 2009-02 27 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00684528

    A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin

    Not yet reported Meir Medical Center 1000 participants Est. completion 2012-12 1 site
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT00691314

    Efficacy and Safety of Stent Implantation in Symptomatic Extra- and Intracranial Artery Stenosis

    Not yet reported Peking Union Medical College Hospital 300 participants Est. completion 2010-12 10 sites
    Cardiovascular disease Other conditions: Transient Ischemic Attack, Atherosclerosis, Stenosis, Stents
    View official trial listing →
  • Status unknown NCT NCT00699322

    Effect of Dipeptidyl Peptidase-IV Inhibitor and Sulfonylurea on Glucose Variability and Oxidative Stress

    Not yet reported The Catholic University of Korea 36 participants Est. completion 2010-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00700817

    The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Novo Nordisk A/S 665 participants Est. completion 2010-06 166 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00703508

    Pharmacogenetics of Metformin Action in PCOS

    Not yet reported Virginia Commonwealth University 55 participants Est. completion 2014-03 2 sites
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00703755

    A Randomized, Double-Blind Trial Comparing the Efficacy and Safety of Fenofibrate, Metformin, Their Combination and Placebo in Patients With Metabolic Syndrome.

    Not yet reported Solvay Pharmaceuticals 2288 participants Est. completion 2004-06 101 sites
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT00743002

    A Trial of TT223 in Patients With Type 2 Diabetes Who Are Taking Metformin and/or Thiazolidinedione

    Not yet reported OPKO Health, Inc. 87 participants Est. completion 2009-12 20 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00745433

    Switch From Metformin Monotherapy to a Bitherapy With Metformin and Repaglinide

    Novo Nordisk A/S 906 participants Est. completion 2009-03 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00763451

    GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin

    Not yet reported Sanofi 484 participants Est. completion 2011-01 15 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00775164

    Pioglitazone Therapy in Obese Children With Insulin Resistance: A Randomized, Controlled Pilot Study

    Not yet reported University of Minnesota Est. completion 2011-02
    Other conditions: Obesity, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT00778427

    Bioequivalence Study of Metformin Hydrochloride 1000mg Tablets Under Fasting Conditions

    Not yet reported Ranbaxy Laboratories Limited 32 participants Est. completion 2006-04 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00817271

    To Evaluate the Response to Glucagon During Hypoglycemia

    Not yet reported AstraZeneca 8 participants Est. completion 2009-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00819884

    To Evaluate 24-hr Glucose After OD vs BD AZD1656

    Not yet reported AstraZeneca 36 participants Est. completion 2009-05 1 site
    Other conditions: Type II Diabetes
    View official trial listing →
  • Completed NCT NCT00820573

    Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DM

    Not yet reported The University of Texas Health Science Center at San Antonio 16 participants Est. completion 2012-10 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00823680

    A Study of RO5093151 and RO5027838 in Patients With Type 2 Diabetes Mellitus on a Stable Dose of Metformin

    Not yet reported Hoffmann-La Roche 110 participants Est. completion 2009-08 5 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00832390

    Study to Assess the Efficacy and Safety of Sitagliptin in Recently Diagnosed, Naive Type 2 Diabetics With Inadequate Glycemic Control on Diet and Exercise (0431-158)

    Not yet reported Merck Sharp & Dohme LLC 29 participants Est. completion 2008-07-11
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00839527

    A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes

    Not yet reported GlaxoSmithKline 685 participants Est. completion 2013-04 358 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00859898

    Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 Diabetes

    Not yet reported AstraZeneca 1093 participants Est. completion 2010-05 123 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00864669

    A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Non-fasting Conditions

    Not yet reported Actavis Inc. 32 participants Est. completion 2002-03 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865072

    A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 40 participants Est. completion 2003-08 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865839

    A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 32 participants Est. completion 2002-03 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00871936

    A Comparison of SLx-4090 in Combination With Metformin Versus Metformin Therapy Alone in Patients With Type 2 Diabetes

    Not yet reported Response Pharmaceuticals 82 participants Est. completion 2009-10 12 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00883766

    Polycystic Ovary Syndrome (PCOS) and In Vitro Fertilization (IVF): A Comparison Between Standard Long Protocol Versus an Antagonist Protocol Starting on Day 1

    Not yet reported Fundacion Dexeus 172 participants Est. completion 2012-06 1 site
    Other conditions: Polycystic Ovary Syndrome, In Vitro Fertilization
    View official trial listing →
  • Completed NCT NCT00897390

    Bioequivalence Study of Saxagliptin and Glucophage Combination Formulations in Healthy Subjects (B)

    Not yet reported AstraZeneca 24 participants Est. completion 2009-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00915772

    Treatment of Type 2 Diabetes With Linagliptin 2.5 mg Bid + Metformin 500 or 1000 mg Bid and Metformin 1000 mg Bid

    Not yet reported Boehringer Ingelheim 567 participants 112 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00924573

    Comparative Study of HOE490 O (Glimepiride and Metformin) Compared With Placebo on Top of Glimepiride

    Not yet reported Sanofi 189 participants Est. completion 2010-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00940797

    Effect of DMMET-01 on Insulin Sensitivity in Naive Type 2 Diabetes Patients (CLAMP)

    Not yet reported Laboratorios Silanes S.A. de C.V. 20 participants 1 site
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT00941148

    Beta-Cell Function of Insulin Glargine Compared to Neutral Protamine Hagedorn (NPH) Insuline and to Insulin Detemir in Combination With Metformin

    Not yet reported ikfe-CRO GmbH 30 participants Est. completion 2009-03 1 site
    Other conditions: Type 2 Diabetic Patients, Insufficient Metabolic Control, OAD Treatment
    View official trial listing →
  • Completed NCT NCT00941239

    Tolerability and Pharmacokinetics of Metformin and Metformin Extended Release (ER)

    Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2007-02 1 site
    Other conditions: Healthy
    View official trial listing →
  • Suspended NCT NCT00948324

    Effect of Intensive Therapy Associated With CSII on β-cell Function With Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 400 participants Est. completion 2021-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00948402

    PED/PEA-15 Protein, PCOS, Obesity, Insulin Sensitivity Indexes, Metformin, Oral Contraceptives

    Not yet reported Federico II University 20 participants Est. completion 2009-01
    Other conditions: Polycystic Ovarian Syndrome, Insulin Sensitivity
    View official trial listing →
  • Completed NCT NCT00959101

    Comparison of Repaglinide and Metformin Combination Tablet Versus Repaglinide and Metformin as Separate Tablets in Healthy Volunteers

    Not yet reported Novo Nordisk A/S 42 participants Est. completion 2009-10 1 site
    Other conditions: Diabetes, Healthy
    View official trial listing →
  • Completed NCT NCT00965991

    Metformin Compared to Glyburide in Gestational Diabetes

    Not yet reported University of New Mexico 149 participants Est. completion 2023-08 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT00970593

    Study Evaluating Safety, Tolerability, And Action Of OAP-189 In Subjects With Type 2 Diabetes On Metformin

    Not yet reported Pfizer 92 participants Est. completion 2011-07-25 2 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00971295

    Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Metformin in Healthy Volunteers

    Not yet reported Bial - Portela C S.A. 20 participants Est. completion 2008-09 1 site Stand-alone
    Other conditions: Neuropathic Pain
    View official trial listing →
  • Completed NCT NCT00972283

    Comparison of NN1250 With Insulin Glargine Plus Insulin Aspart With/Without Metformin and With/Without Pioglitazone in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 1006 participants Est. completion 2010-10-28 136 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00975065

    Galvus on Met Phase 4 Study : Study to Evaluate the Efficacy and Safety of Early Combination of Vildagliptin and Metformin in Patients With Type 2 Diabetes Mellitus

    Not yet reported Handok Inc. 266 participants Est. completion 2012-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00998686

    Safety and Efficacy Study of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

    Not yet reported Phenomix 650 participants Est. completion 2011-11 44 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01069965

    Safety and Efficacy of BGP-15 in Patients With Type 2 Diabetes Mellitus

    Not yet reported N-Gene Research Laboratories, Inc. 196 participants Est. completion 2011-10 30 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01077479

    Metformin in Preventing Androgen Deprivation Therapy Induced Insulin Resistance and Metabolic Syndrome

    Not yet reported Western Sydney Local Health District 28 participants Est. completion 2013-06 1 site
    Metabolic syndrome Other conditions: Hypercholesterolemia
    View official trial listing →
  • Completed NCT NCT01082120

    Investigate the Effect of AZD1656 on the Pharmacokinetics of Pioglitazone and Vice Versa in Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 28 participants Est. completion 2010-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01087983

    Lapatinib With Sirolimus or Metformin

    Not yet reported M.D. Anderson Cancer Center 111 participants Est. completion 2015-09 1 site
    Other conditions: Advanced Cancers
    View official trial listing →
  • Completed NCT NCT01089166

    Study to Compare the Bioavailability of Extended Release Metformin HCl Tablet Versus Glucophage XR® Tablets in Healthy Human Volunteers Under Fasting Condition

    Not yet reported Torrent Pharmaceuticals Limited 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01089179

    Bioequivalence Study of Metformin Hydrochloride Extended Release 500 mg Tablet Versus Glucophage XR® 500 mg Tablet in Healthy Volunteers Under Fed Conditions

    Not yet reported Torrent Pharmaceuticals Limited 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01095991

    Investigate the Effect of AZD1656 on the Pharmacokinetics of Sitagliptin in Patients With Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 12 participants Est. completion 2010-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01103609

    Investigate the Effect of AZD1656 on the Pharmacokinetics and Pharmacodynamics of Warfarin in Type 2 Diabetes Mellitus (T2DM) Patients

    Not yet reported AstraZeneca 16 participants Est. completion 2010-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01106651

    A Safety and Efficacy Study of Canagliflozin in Older Patients (55 to 80 Years of Age) With Type 2 Diabetes Mellitus

    Not yet reported Janssen Research & Development, LLC 716 participants Est. completion 2013-05 86 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01144728

    Initiation and Titration of Amaryl

    Not yet reported Sanofi 172 participants Est. completion 2010-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01156597

    Effects of Pioglitazone on High-density Lipoprotein (HDL) Function in Persons With Diabetes

    Not yet reported University of Miami 30 participants Est. completion 2010-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01162772

    Influence of DPP-4 on Inflammatory Parameters in Diabetics: Gender Aspects

    Medical University of Vienna 80 participants 1 site
    Type 2 diabetes Other conditions: Cardiovascular Risk, Endothelial Dysfunction
    View official trial listing →
  • Completed NCT NCT01192139

    Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin XR Tablet (Manufactured in Mt Vernon, IN) Relative to 5 mg Saxagliptin Tablet and 500 mg Metformin XR Tablet (Manufactured in Evansville, IN)

    Not yet reported AstraZeneca 30 participants Est. completion 2009-12 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01204580

    ADIponectin and Asymmetric Dimethylarginine (ADMA) Level in Type-2 Diabetes Patients After 12 Weeks of Treatment With GlimepiRide And Metformin Fixed Dose Combination

    Not yet reported Sanofi 40 participants Est. completion 2012-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01210001

    Efficacy and Safety of Empagliflozin (BI 10773) in Type 2 Diabetes Patients on a Background of Pioglitazone Alone or With Metformin

    Not yet reported Boehringer Ingelheim 499 participants 68 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01213563

    Management of Type 2 Diabetes After Gastric Bypass Surgery

    Not yet reported Imperial College London 50 participants Est. completion 2010-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01215097

    Efficacy and Safety Study of Linagliptin (5 mg Administered Orally Once Daily) Over 24 Weeks in Type 2 Diabetic Patients With Insufficient Glycaemic Control Despite Metformin Therapy

    Not yet reported Boehringer Ingelheim 306 participants Est. completion 2012-04 19 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01215331

    Gestational Diabetes: Insulin or Oral Hypoglycemic Agents?

    Not yet reported Université de Sherbrooke 73 participants Est. completion 2016-05 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01228240

    The Efficacy of Metformin Produced by Pars Mino Co in Comparison With Canadian Apotex Co.

    Not yet reported Zanjan University of Medical Sciences 18 participants Est. completion 2009-09
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01233622

    Safety and Efficacy of Galvus as add-on Therapy to Metformin Plus Glimepiride

    Not yet reported Novartis 317 participants Est. completion 2011-11 55 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01237522

    A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers

    Not yet reported University of Southern Denmark 50 participants Est. completion 2010-12 1 site
    Other conditions: Metformin, Organic Cation Transporter 2, Polymorphism,Single Nucleotide
    View official trial listing →
  • Completed NCT NCT01238978

    Phase 4 Study in the Elderly Patients With T2DM

    Not yet reported Novartis 46 participants Est. completion 2011-12 15 sites
    Type 2 diabetes Other conditions: Elderly
    View official trial listing →
  • Completed NCT NCT01258075

    Colesevelam for Children With Type 2 Diabetes

    Not yet reported Daiichi Sankyo 236 participants Est. completion 2020-04-21 24 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01289990

    Safety and Efficacy of Empagliflozin (BI 10773) and Sitagliptin Versus Placebo Over 76 Weeks in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 2705 participants Est. completion 2013-05 243 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01294553

    An Open Label, Multi-centre, Non-interventional Post-marketing Surveillance to Monitor the Safety and/or Efficacy of AVANDAMET Between June 2004 and January 2010

    GlaxoSmithKline 717 participants Est. completion 2010-01
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01300637

    Effects of Adjunctive Metformin on Metabolic Profiles in Clozapine-treated Schizophrenic Patients

    Not yet reported Taipei Medical University WanFang Hospital 60 participants Est. completion 2011-07 1 site
    Metabolic syndrome Other conditions: Obesity, Schizophrenia
    View official trial listing →
  • Completed NCT NCT01302145

    Drug to Drug Interaction Study With ASP1941 and Metformin

    Not yet reported Astellas Pharma Inc 36 participants Est. completion 2009-12-09 5 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01305551

    BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States

    Not yet reported AstraZeneca Est. completion 2011-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01312467

    Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI

    Not yet reported National Cancer Institute (NCI) 45 participants Est. completion 2014-12 4 sites Stand-alone
    Other conditions: Adenomatous Polyp, Colorectal Cancer, Obesity
    View official trial listing →
  • Terminated NCT NCT01336673

    Glucophage XR® Observational Study

    Merck KGaA, Darmstadt, Germany 518 participants Est. completion 2013-06 1 site
    Type 2 diabetes Other conditions: GI Side Effect
    View official trial listing →
  • Completed NCT NCT01340300

    Exercise and Metformin in Colorectal and Breast Cancer Survivors

    Not yet reported Dana-Farber Cancer Institute 139 participants Est. completion 2017-12 2 sites
    Other conditions: Colorectal Cancer, Breast Cancer
    View official trial listing →
  • Completed NCT NCT01353391

    Metformin in Women With Type 2 Diabetes in Pregnancy Trial

    Not yet reported Mount Sinai Hospital, Canada 500 participants Est. completion 2019-06-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01357148

    A Post Marketing Safety Study of Sitagliptin Phosphate/Metformin Hydrochloride (JANUMET®) (MK-0431A-235)

    Merck Sharp & Dohme LLC 143 participants Est. completion 2010-05
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01365091

    Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-Brazil

    Not yet reported AstraZeneca 112 participants Est. completion 2011-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01366391

    Therapeutic Monitoring of Metformin in Women With Polycystic Ovary Syndrome

    Not yet reported Biocinese 24 participants Est. completion 2011-10 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01370707

    A Study to Evaluate the Efficacy and Safety of CJ-30001 and CJ-30002 in Type 2 Diabetes Mellitus Patients

    Not yet reported HK inno.N Corporation 187 participants Est. completion 2012-07 21 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT01417897

    Human Insulin Analogs: Evaluation of Inflammatory mRNA Expression of Macrophages and Endothelial Function of Short-acting Insulin - HERMES Pilot Study

    Not yet reported ikfe-CRO GmbH 12 participants Est. completion 2012-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01420692

    The Effects of Insulin Detemir and Gliclazide-MR Treatments on Endothelial Functions in Patients With Type 2 Diabetes

    Not yet reported Ankara University 64 participants Est. completion 2012-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01429506

    Efficacy of Laparoscopic Sleeve Gastrectomy and Intensive Medical Management in Obese Type 2 Diabetes

    Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2012-08 1 site
    Other conditions: Diabetes Mellitus, Obesity
    View official trial listing →
  • Terminated NCT NCT01430351

    Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy

    Not yet reported M.D. Anderson Cancer Center 144 participants Est. completion 2025-02-02 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Glioblastoma, Supratentorial Glioblastoma
    View official trial listing →
  • Completed NCT NCT01459094

    Effect of Food on a Fixed Dose Combination Tablet of Canagliflozin and Metformin Immediate Release in Healthy Volunteers

    Not yet reported Janssen Research & Development, LLC 24 participants Est. completion 2011-12
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT01459445

    Metformin+ Drospirenone/ethinylestradiol30µg and Flow-mediated Dilation in Polycystic Ovary Syndrome

    Not yet reported Iuliu Hatieganu University of Medicine and Pharmacy 26 participants Est. completion 2012-01 1 site
    Other conditions: Polycystic Ovary Syndrome, Endothelial Dysfunction
    View official trial listing →
  • Completed NCT NCT01459809

    Efficacy and Safety Comparison of Metformin/Glimepiride Combination Versus Each Compound Alone in New Diagnosed Type 2 Diabetes Patients

    Not yet reported Sanofi 538 participants Est. completion 2014-01 55 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01462266

    Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260)

    Not yet reported Merck Sharp & Dohme LLC 660 participants Est. completion 2013-06-07
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01463774

    A Study to Assess the Bioequivalence of 2 Fixed Dose Combination Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers

    Not yet reported Janssen Research & Development, LLC 74 participants Est. completion 2011-12 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01464437

    AMG 151 Amgen Protocol Number 20100761

    Not yet reported Amgen 236 participants Est. completion 2012-12 77 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01474018

    QR-Bromocriptine as an Adjunct to Insulin and Metformin in the Treatment of Type 2 Diabetes

    Not yet reported University of Texas Southwestern Medical Center 15 participants Est. completion 2012-06 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01485614

    Study to Assess Safety & Efficacy of Sitagliptin as Initial Oral Therapy for Treatment of Type 2 Diabetes Mellitus in Pediatric Participants. (MK-0431-083)

    Not yet reported Merck Sharp & Dohme LLC 200 participants Est. completion 2019-10-09
    Type 2 diabetes Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT01486966

    Comparing Efficacy and Safety of Insulin Detemir Plus Insulin Aspart and NPH Insulin Plus Human Soluble Insulin With or Without Metformin in Chinese Patients With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 58 participants Est. completion 2012-06 6 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01509001

    Study of Metabolic and Haemodynamic Effects of Metformin and Glimepiride in Patients With Type 2 Diabetes Mellitus

    Not yet reported University of Sao Paulo 20 participants Est. completion 2012-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01528046

    Metformin in Children With Relapsed or Refractory Solid Tumors

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 26 participants Est. completion 2020-02-03 14 sites
    Other conditions: Solid Tumors, Primary Brain Tumors
    View official trial listing →
  • Status unknown NCT NCT01529177

    Metformin for the Treatment of Unexplained Oligozspermia

    Not yet reported The Egyptian IVF-ET Center 600 participants Est. completion 2017-02 1 site
    Other conditions: Infertility
    View official trial listing →
  • Completed NCT NCT01541956

    Efficacy of VIldagliptin aS an Add-on Therapy to Metformin Compared to Metformin Up-TitratION in Chinese Patients With Type 2 Diabetes.(VISION)

    Not yet reported Novartis Pharmaceuticals 3091 participants Est. completion 2013-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01560481

    Clinical Trial to Evaluate Safety and pK Profile of Metformin Glycinate in Healthy Volunteers

    Not yet reported Laboratorios Silanes S.A. de C.V. 49 participants Est. completion 2013-03 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01563120

    A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus

    Not yet reported HaEmek Medical Center, Israel 108 participants Est. completion 2014-12 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT01566799

    Metformin Plus Neoadjuvant Chemotherapy in Breast Cancer

    Not yet reported Instituto Nacional de Cancerologia de Mexico 60 participants Est. completion 2014-04 1 site
    Other conditions: Locally Advanced Malignant Neoplasm
    View official trial listing →
  • Completed NCT NCT01573377

    Efficacy of Metformin and Diane-35 on PCOS Patients,a Randomized, Controlled, Prospective Clinical Trial

    Not yet reported Chongqing Medical University 40 participants Est. completion 2013-02 1 site
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT01579812

    Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic Patients

    Not yet reported University of Michigan Rogel Cancer Center 90 participants Est. completion 2017-07 1 site
    Other conditions: Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
    View official trial listing →
  • Completed NCT NCT01581931

    Bioequivalence of Metformin Under Fed Conditions After Administration of Linagliptin / Metformin Fixed Dose Combination Tablet and Single Tablets

    Not yet reported Boehringer Ingelheim 32 participants Est. completion 2012-06 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01590771

    A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Sulfonylurea With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-253)

    Not yet reported Merck Sharp & Dohme LLC 498 participants Est. completion 2014-06-24
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01595789

    The Effect of Liraglutide on the Treatment of Coronary Artery Disease and Type 2 Diabetes

    Not yet reported Haugaard, Steen Bendix, M.D., DMSc 41 participants Est. completion 2015-07 1 site
    Cardiovascular diseaseType 2 diabetes
    View official trial listing →
  • Completed NCT NCT01612858

    Metabolic Abnormalities in HIV-infected Persons

    Not yet reported Tufts Medical Center 20 participants Est. completion 2014-11 1 site
    Other conditions: Lipodystrophy, HIV Infection
    View official trial listing →
  • Completed NCT NCT01620593

    Castration Compared to Castration Plus Metformin as First Line Treatment for Patients With Advanced Prostate Cancer

    Not yet reported The University of Texas Health Science Center at San Antonio 41 participants Est. completion 2016-09 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Withdrawn NCT NCT01638988

    Clomifene Citrate Versus Metformin in First-line Treatment of Infertility in Patients With Polycystic Ovary Syndrome and a Resistance to Insulin

    Not yet reported Clinique Ovo Est. completion 2015-12 1 site
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Terminated NCT NCT01654640

    The Effect of Metformin on Obesity and Metabolic Disturbance in Patients Taking Clozapine

    Not yet reported Seoul National University Hospital 15 participants Est. completion 2015-04 1 site
    Other conditions: Schizophrenia
    View official trial listing →
  • Completed NCT NCT01658501

    Phase 2b Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM

    Not yet reported PhaseBio Pharmaceuticals Inc. 593 participants Est. completion 2013-07 93 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01662674

    BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone

    Not yet reported LG Life Sciences 27 participants Est. completion 2013-03 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01677260

    Bioequivalence Study of Two Formulations of 500 mg Metformin Extended Release Tablet

    Not yet reported Dexa Medica Group 38 participants Est. completion 2010-01 1 site Stand-alone
    Other conditions: Metformin XR BE Study in Healthy Volunteers With Single and Multiple Dose
    View official trial listing →
  • Completed NCT NCT01677897

    Impact of the Addition of Metformin to Abiraterone in Metastatic Prostate Cancer Patients

    Not yet reported Kantonsspital Graubünden 25 participants Est. completion 2018-06 1 site
    Other conditions: Metastatic Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01679574

    Letrozole or Combined Clomiphene Citrate Metformin as a First Line Treatment in Women With Polycystic Ovarian Syndrome

    Not yet reported Assiut University 200 participants Est. completion 2012-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01697566

    An Endometrial Cancer Chemoprevention Study of Metformin

    Not yet reported M.D. Anderson Cancer Center 29 participants Est. completion 2024-05-30 1 site
    Other conditions: Gynecology
    View official trial listing →
  • Completed NCT NCT01708902

    Study to Compare the Efficacy and Safety of Administration of the Fix Dose Combination of Linagliptin Plus Metformin in Drug naïve Type 2 Patients

    Not yet reported Boehringer Ingelheim 876 participants Est. completion 2014-04 56 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01710553

    BE STUDY OF METFORMIN GSK 1000mg

    Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-07
    Other conditions: Diabetic Foot
    View official trial listing →
  • Completed NCT NCT01711320

    Effect of Omeprazole on Metformin

    Not yet reported Xijing Hospital 20 participants Est. completion 2012-12 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01718093

    A Pilot Study to Assess the Glucose Lowering Effect of Metformin and Sitagliptin in Adolescents With Type 1 Diabetes

    Not yet reported Baylor College of Medicine 21 participants Est. completion 2015-12 1 site
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT01719003

    Safety and Efficacy Study of Empagliflozin and Metformin for 24 Weeks in Treatment Naive Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 1413 participants Est. completion 2014-12 190 sites
    Type 2 diabetes Other conditions: Hyperglycemia
    View official trial listing →
  • Completed NCT NCT01720290

    Comparison of Repaglinide and Metformin Administered Alone or in Combination in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 150 participants Est. completion 2003-02-25 3 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01725126

    To Investigate the Safety, Tolerability and Pharmacodynamics of GSK2890457 in Healthy Volunteers and Subjects With Type 2 Diabetes

    Not yet reported GlaxoSmithKline 53 participants Est. completion 2013-09-12 3 sites
    Other conditions: Obesity
    View official trial listing →
  • Status unknown NCT NCT01751321

    Glucose Variability With DPP-4 Inhibition

    Not yet reported Research Clinical Centre of the Russian Railways, JSC 50 participants Est. completion 2013-10
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01755156

    A Study to Evaluate the Safety, Tolerability, and Efficacy of the Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Therapy (MK-3102-024)

    Not yet reported Merck Sharp & Dohme LLC 402 participants Est. completion 2016-03-16
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01755494

    A Bioequivalence Study of the Fixed Dose Combinations of Saxagliptin/Metformin XR Relative to Co-Administration

    Not yet reported AstraZeneca 64 participants Est. completion 2013-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01763346

    Beta Cell Restoration Through Fat Mitigation

    Not yet reported University of Southern California 88 participants Est. completion 2018-06 1 site
    PrediabetesType 2 diabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT01765894

    Influence of Moderate Exercise on Blood Glucose in Type 2 Diabetics and Healthy Controls

    University of Copenhagen 24 participants Est. completion 2013-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01775579

    Evaluating a Pharmacokinetic Drug Interaction Between Metformin Hydrochloride and Rosuvastatin Calcium

    Not yet reported Hanmi Pharmaceutical Company Limited 36 participants Est. completion 2013-06 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01792830

    Efficacy and Safety of a Glargine-based Hospital Discharge Algorithm in Coronary Artery Bypass Graft (CABG) Patients

    Not yet reported Emory University 175 participants Est. completion 2014-02 3 sites
    Other conditions: Poor Glycemic Control
    View official trial listing →
  • Completed NCT NCT01804049

    Metformin and Muscle in Insulin-resistant Older Veterans

    Not yet reported, Not yet reported VA Office of Research and Development 120 participants Est. completion 2018-08-31 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT01809327

    A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise

    Not yet reported Janssen Research & Development, LLC 1186 participants Est. completion 2014-12-02 129 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01819129

    Efficacy and Safety of FIAsp Compared to Insulin Aspart in Combination With Insulin Glargine and Metformin in Adults With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 881 participants Est. completion 2015-01-22 144 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01819272

    Assessing the Efficacy, Safety, and Tolerability of Met DR in Subjects With T2DM Over 12 Weeks

    Not yet reported Elcelyx Therapeutics, Inc. 240 participants Est. completion 2013-09
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01845831

    Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes

    Not yet reported Emory University 292 participants Est. completion 2016-04 5 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01850615

    Efficacy and Safety of FIAsp in a Basal-bolus Regimen Versus Basal Insulin Therapy, Both in Combination With Metformin in Adult Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 323 participants Est. completion 2014-11-17 58 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01868542

    A Trial Comparing the Glycaemic Control of Levemir® Administered Once Daily According to Two Insulin Detemir Titration Algorithms After 20 Weeks in Subjects With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin Treatment With or Without Other Anti-diabetic Drugs (OADs)

    Not yet reported Novo Nordisk A/S 46 participants Est. completion 2015-05 6 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01877564

    A Randomized Pilot Study to Evaluate the Effects of a Short Course of Metformin Versus No Therapy in the Period Prior to Hysterectomy for Grade 1-2 Adenocarcinoma of the Endometrium in Obese Non-Diabetic Women

    Not yet reported University of Arkansas 10 participants Est. completion 2017-07-10 1 site
    Other conditions: Adenocarcinoma of the Endometrium
    View official trial listing →
  • Completed NCT NCT01881828

    Metformin Therapy for Overweight Adolescents With Type 1 Diabetes

    Not yet reported Jaeb Center for Health Research 164 participants Est. completion 2014-12 1 site
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT01882907

    Safety and Efficacy Study to Compare Vildagliptin to Pioglitazone as Adding on Metformin in Type 2 Diabetes

    Not yet reported Pusan National University Hospital 287 participants Est. completion 2013-03 15 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01885013

    Myocet + Cyclophosphamide + Metformin Vs Myocet + Cyclophosphamide in 1st Line Treatment of HER2 Neg. Metastatic Breast Cancer Patients

    Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 126 participants Est. completion 2015-05 25 sites
    Other conditions: Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
    View official trial listing →
  • Completed NCT NCT01890122

    Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 Diabetes

    Not yet reported Takeda 647 participants Est. completion 2015-10 45 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01890629

    Effects of Gemigliptin Versus Sitagliptin or Glimepiride With Metformin on Glucose Variability(MAGE, Glucose SD) Patients With Type 2 DM(STABLE Study)

    Not yet reported LG Life Sciences 69 participants Est. completion 2014-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT01905046

    Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

    Not yet reported Alliance for Clinical Trials in Oncology 86 participants Est. completion 2026-11 27 sites Stand-alone
    Other conditions: Atypical Ductal Breast Hyperplasia, BRCA1 Mutation Carrier, BRCA2 Mutation Carrier, Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in Situ
    View official trial listing →
  • Completed NCT NCT01911468

    Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin

    Not yet reported University Medical Centre Ljubljana 36 participants Est. completion 2013-04 1 site
    Other conditions: PCOS, Obesity
    View official trial listing →
  • Completed NCT NCT01929863

    Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 in Type 2 Diabetes Patients Taking Metformin

    Not yet reported GlaxoSmithKline 16 participants Est. completion 2013-11-21 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01958671

    A Study of the Efficacy and Safety of Ertugliflozin Monotherapy in the Treatment of Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control Despite Diet and Exercise (MK-8835-003, VERTIS MONO)

    Not yet reported Merck Sharp & Dohme LLC 461 participants Est. completion 2016-07-28
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01965756

    Effect of Insulin Sensitizer Metformin on AD Biomarkers

    Not yet reported University of Pennsylvania 20 participants Est. completion 2017-04 1 site
    Other conditions: Alzheimer's Disease, Vascular Dementia, Dementia, Memory Impairment
    View official trial listing →
  • Completed NCT NCT01971034

    Treatment of Patients With Advanced Pancreatic Cancer After Gemcitabine Failure.

    Not yet reported Instituto do Cancer do Estado de São Paulo 41 participants 1 site
    Other conditions: Pancreatic Adenocarcinoma Advanced or Metastatic
    View official trial listing →
  • Withdrawn NCT NCT01984606

    Efficacy and Safety of Empagliflozin Versus Sitagliptin in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim Est. completion 2017-02
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01996696

    Prevention of Metabolic Syndrome and Increased Weight Using Metformin Concurrent to Androgen Deprivation Therapy and Radiotherapy for Locally Advanced Adenocarcinoma of the Prostate

    Not yet reported AHS Cancer Control Alberta 83 participants Est. completion 2020-11 3 sites
    Other conditions: Prostatic Neoplasm
    View official trial listing →
  • Completed NCT NCT02006836

    Glycemic Responses to Majia Pomelos in Type 2 Diabetic Patients

    Not yet reported Huazhong University of Science and Technology 59 participants Est. completion 2013-12 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02028767

    Bioequivalence Study in Healthy Volunteers for Empagliflozin/Metformin Fixed Dose Combination Compared to Separate Tablets

    Not yet reported Boehringer Ingelheim 32 participants Est. completion 2014-02 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02035787

    Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients

    Not yet reported UNC Lineberger Comprehensive Cancer Center 20 participants Est. completion 2024-04-12 2 sites
    Other conditions: Complex Atypical Hyperplasia, Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT02036515

    Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

    Not yet reported Merck Sharp & Dohme LLC 464 participants Est. completion 2016-06-06
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02048761

    Locally Delivered 1% Metformin Gel in the Treatment of Intrabony Defects in Chronic Periodontitis

    Not yet reported Government Dental College and Research Institute, Bangalore 65 participants Est. completion 2014-02 1 site
    Other conditions: Intrabony Defects in Chronic Periodontitis
    View official trial listing →
  • Completed NCT NCT02050074

    The Role of Metformin and Colesevelam in Human GLP-1 Secretion

    Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2014-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02051842

    Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis

    Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 100 participants Est. completion 2020-12 1 site
    MASLDPrediabetes
    View official trial listing →
  • Completed NCT NCT02058160

    Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes

    Not yet reported Sanofi 736 participants Est. completion 2015-07 236 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02076347

    Comparison of Two Pharmacist-led Population Management Approaches to Increase Monitoring of Vitamin B12 and Serum Creatinine Levels for Patients on Metformin

    Not yet reported Ohio State University 489 participants Est. completion 2015-10 1 site
    Type 2 diabetes Other conditions: Vitamin B12 Deficiency, Neuropathy, Anemia
    View official trial listing →
  • Completed NCT NCT02080377

    A Feasibility Study Looking at the Use of Glibenclamide and metfoRmin Versus stAndard Care in gEstational diabeteS

    Not yet reported University of Edinburgh 23 participants Est. completion 2016-03 5 sites
    Other conditions: Pregnancy, Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT02088034

    Intervention to Promote Weight Loss in Latinas At-risk for Diabetes

    Not yet reported Temple University 92 participants Est. completion 2016-02 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02088918

    A Open-label, Single-dose, 2-Sequence, 2-Period, Crossover Study to Assess Safety and Pharmacokinetics of a Nateglinide/Metformin HCl Combined Tablet Compared With a Nateglinide 120 mg Tablet and Metformin HCl 500 mg Tablet Under Fasting Conditions in Healthy Male Subjects

    Not yet reported IlDong Pharmaceutical Co Ltd 40 participants 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT02104804

    Evaluate the Efficacy and Safety of Saxagliptin Added to Insulin Monotherapy or to Insulin Combined With Metformin in Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control

    Not yet reported AstraZeneca 953 participants Est. completion 2016-02-26 11 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02106923

    Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Extended Release (XR) Compared With Single Tablets

    Not yet reported Boehringer Ingelheim 72 participants Est. completion 2014-07 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02113163

    PK Study Comparing Metformin Eicosapentaenoate to a Combined Dose of Metformin Hydrochloride and Ethyl Ester EPA

    Not yet reported Thetis Pharmaceuticals LLC 32 participants Est. completion 2014-07 1 site
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent, Hypertriglyceridemia
    View official trial listing →
  • Completed NCT NCT02128932

    Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 1089 participants Est. completion 2015-09-03 231 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02138097

    Oral and Non-insulin Injected Hypoglycemic Therapy Utilization Patterns

    Boehringer Ingelheim 615067 participants Est. completion 2014-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02145611

    Vildagliptin vs. Glibenclamide in Endothelial Function in Type 2 Diabetes and Hypertension

    Not yet reported Dr. José Fernando Vilela-Martin MD PhD 50 participants Est. completion 2016-05 1 site
    Type 2 diabetes Other conditions: Hypertension, Endothelial Dysfunction
    View official trial listing →
  • Completed NCT NCT02183935

    Treatment of Morbidly Obese Adolescent With a Duodena-jejunal Liner

    Not yet reported University Medical Centre Ljubljana 22 participants Est. completion 2018-12-20 1 site
    Metabolic syndrome Other conditions: Obesity, Diabetes
    View official trial listing →
  • Completed NCT NCT02184832

    Dietary Intake of Tryptophan and Metformin Response

    Not yet reported Massachusetts General Hospital 20 participants Est. completion 2016-03 1 site
    Other conditions: Metformin Response, Fasting Glucose, Tryptophan Concentration, Metformin Concentration, Diet Tolerability
    View official trial listing →
  • Completed NCT NCT02202161

    A Study Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 Administered With Metformin to Type 2 Diabetes Patients

    Not yet reported GlaxoSmithKline 70 participants Est. completion 2015-01-30 4 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02206607

    Study To Compare Single Dose Of Three Modified Release Formulations Of PF-04937319 With Immediate Release Material-Sparing-Tablet (IR MST) Formulation Previously Studied In Adults With Type 2 Diabetes Mellitus.

    Not yet reported Pfizer 39 participants Est. completion 2015-01 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02220647

    Bioequivalence of a 2.5 mg Linagliptin / 850 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 850 mg Tablets in Healthy Volunteers

    Not yet reported Boehringer Ingelheim 96 participants
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02221414

    Bioequivalence of a 2.5 mg Linagliptin / 500 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 500 mg Tablets Administered Together in Healthy Volunteers

    Not yet reported Boehringer Ingelheim 95 participants
    Other conditions: Healthy
    View official trial listing →
  • Withdrawn NCT NCT02229240

    Albiglutide Versus Placebo Added-on to Basal-Bolus Insulin Therapy in Subjects With Type 2 Diabetes Mellitus

    Not yet reported GlaxoSmithKline Est. completion 2015-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02231021

    The Practical Evidence of Antidiabetic Combination Therapy in Korea

    Not yet reported Kun-Ho Yoon 216 participants Est. completion 2019-01-28 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02246257

    Early Rheumatoid Arthritis COR Intervention

    Not yet reported MD, PhD, Annemarie Lyng Svensson 300 participants Est. completion 2024-09 1 site
    Cardiovascular disease Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02272556

    Investigating the Role of the Polyol Pathway in the Central Nervous System

    Not yet reported Yale University 138 participants Est. completion 2022-05-18 1 site
    Other conditions: Hyperglycemia
    View official trial listing →
  • Completed NCT NCT02276274

    Effect of Food on the Pharmacokinetics of Single Oral Dose Administration of a Fixed-Dose Combination of SYR-322 and Metformin Hydrochloride in Healthy Adult Male Subjects

    Not yet reported Takeda 12 participants Est. completion 2014-06 1 site
    Other conditions: Clinical Pharmacology
    View official trial listing →
  • Completed NCT NCT02278965

    Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer

    Not yet reported Katherine D. Crew 19 participants Est. completion 2017-04-19 1 site
    Other conditions: Stage 0 Breast Carcinoma, Breast Neoplasms, Stage I Breast Carcinoma, Stage II Breast Carcinoma, Stage III Breast Carcinoma
    View official trial listing →
  • Completed NCT NCT02283554

    Platelet Rich Fibrin With 1% Metformin Gel for Treatment of Intrabony Defects

    Not yet reported Government Dental College and Research Institute, Bangalore 120 participants
    Other conditions: Periodontitis
    View official trial listing →
  • Terminated NCT NCT02285855

    Metformin in Non Small Cell Lung Cancer (NSCLC)

    Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2019-01-05 1 site
    Other conditions: Lung Cancer
    View official trial listing →
  • Completed NCT NCT02288273

    Study to Evaluate the Effect of BYDUREON on 24-hour Glucose Control in Metformin Treated Patients With Type 2 Diabetes.

    Not yet reported AstraZeneca 239 participants Est. completion 2015-08 29 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02292290

    Trial for People With Established Type 2 Diabetes During Ramadan

    Not yet reported University of Leicester 99 participants Est. completion 2012-12 2 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02303405

    Hydroxychloroquine Versus Pioglitazone in Combination Treatment for Type 2 Diabetes Mellitus

    Not yet reported Charles Drew University of Medicine and Science 22 participants Est. completion 2017-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02304081

    Saxagliptin in Combination With Dapagliflozin - Effects on Islet Cell Function

    Not yet reported Prof. Dr. Thomas Forst 64 participants Est. completion 2016-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02304536

    Comparison Between Laparoscopic Ovarian Diathermy and Urinary Purified FSH in Women With Clomiphene Citrate Resistant Polycystic Ovarian Syndrome.

    Not yet reported Cairo University 210 participants 2 sites
    Other conditions: Infertility
    View official trial listing →
  • Completed NCT NCT02305381

    Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to Basal Insulin Alone or Basal Insulin in Combination With Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 397 participants Est. completion 2015-11-21 99 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02325960

    A Comparison of Exenatide and Insulin Glargine

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 44 participants Est. completion 2016-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT02336087

    Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery

    Not yet reported City of Hope Medical Center 21 participants Est. completion 2026-12-09 4 sites Stand-alone
    Other conditions: Pancreatic Adenocarcinoma, Unresectable Pancreatic Carcinoma, Stage III Pancreatic Cancer AJCC v6 and v7, Stage IV Pancreatic Cancer AJCC v6 and v7
    View official trial listing →
  • Completed NCT NCT02343926

    Phase 3 Study to Compare the Efficacy and Safety of Gemigliptin and Vildagliptin as Add-on Therapy to Metformin in People With Type 2 Diabetes Inadequately Controlled With Metformin

    Not yet reported Sanofi 443 participants Est. completion 2016-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02354027

    The Drug-drug Interaction of SHR3824 and Metformin

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 12 participants Est. completion 2015-01
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02373865

    Risk of Nocturnal Hypoglycemia and Arrhythmias With Sitagliptin Versus Glimepiride in Patients With Type 2 Diabetes

    Not yet reported GWT-TUD GmbH 4 participants Est. completion 2017-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02378441

    Phase 1 Study to Compare the Safety, Pharmacokinetic Profiles of CJ-30056 and Lipitor 20mg/Glucophage SR 750mg

    Not yet reported HK inno.N Corporation 42 participants Est. completion 2015-08
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT02393573

    Attenuating The Post-Operative Insulin Resistance And Promoting Protein Anabolism

    Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 7 participants Est. completion 2018-03 1 site
    Prediabetes Other conditions: Major Lung or Abdominal Surgery, Insulin Resistance
    View official trial listing →
  • Withdrawn NCT NCT02395237

    COMPOUND (INN): HOE490O - GLIMEPIRIDE / METFORMIN HCl (Amaryl® M)0 (Glimepiride/Metformin Hydrochloride Immediate Release Combination Tablet) in Fed Conditions in Healthy Male and/or Female Subjects.

    Not yet reported Pharmaceutical Research Unit, Jordan Est. completion 2015-12 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02401880

    Effects of Linagliptin in Addition to Empagliflozin on Islet Cell Physiology

    Not yet reported Profil Institut für Stoffwechselforschung GmbH 89 participants Est. completion 2015-12 2 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02420652

    Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy

    Not yet reported Rutgers, The State University of New Jersey 27 participants Est. completion 2019-12-01 1 site Stand-alone
    Other conditions: Recurrent Prostate Carcinoma, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer, Stage III Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT02426294

    Comparison of Pioglitazone Versus Glimepiride in Type 2 Diabetes Inadequately Controlled With Metformin Plus Alogliptin

    Not yet reported Pusan National University Hospital 154 participants Est. completion 2016-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02429258

    Effect of Dapagliflozin on 24-hour Blood Glucose in T2DM Patients Inadequately Controlled With Either Metformin Or Insulin

    Not yet reported AstraZeneca 226 participants Est. completion 2015-10 26 sites
    Other conditions: Type II Diabetes
    View official trial listing →
  • Completed NCT NCT02435277

    An Extension Protocol to Evaluate Dose Comparisons of Leucine-Metformin Combinations in Type 2 Diabetic Patients

    Not yet reported NuSirt Biopharma 50 participants Est. completion 2016-01 9 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02438397

    the Efficacy of Acarbose and Metformin on Blood Glucose Fluctuation When Combined With Premix Insulin

    Not yet reported Shanghai 6th People's Hospital 80 participants Est. completion 2016-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02470039

    Trial to Compare NNC0123-0000-0338 in a Tablet Formulation and Insulin Glargine in Subjects With Type 2 Diabetes Currently Treated With Oral Antidiabetic Therapy

    Not yet reported Novo Nordisk A/S 50 participants Est. completion 2015-12-31 2 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT02472353

    Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

    Not yet reported Avera McKennan Hospital & University Health Center 30 participants Est. completion 2018-05-23 1 site
    Other conditions: Breast Cancer, Breast Tumors
    View official trial listing →
  • Completed NCT NCT02496000

    Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus

    Not yet reported Oramed, Ltd. 188 participants Est. completion 2016-09-13 34 sites
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT02497313

    Effect of Metformin and Cholecystokinin-mediated Gallbladder Emptying on GLP-1 Secretion in Type 2 Diabetes

    Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2016-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02500147

    Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)

    Not yet reported Columbia University 3 participants Est. completion 2021-03-03 1 site
    Metabolic syndrome Other conditions: Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease
    View official trial listing →
  • Status unknown NCT NCT02503943

    Effects of Incretin on the Blood Pressure and Lipid in Patients With Overweight or Obese Diabetes

    Not yet reported Third Affiliated Hospital of Third Military Medical University 90 participants Est. completion 2016-09
    Type 2 diabetes Other conditions: Overweight, Obesity, Masked Hypertension
    View official trial listing →
  • Terminated NCT NCT02549924

    Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus

    Not yet reported University of Guadalajara 22 participants Est. completion 2018-02-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02552355

    Milk Protein Feeding After Aerobic Exercise in Older Adults With Pre-diabetes Taking the Biguanide Metformin

    Not yet reported Colorado State University 56 participants Est. completion 2017-08 1 site
    Other conditions: Physical Activity
    View official trial listing →
  • Completed NCT NCT02561130

    Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Forxiga

    Not yet reported Population Health Research Institute 154 participants Est. completion 2018-12-31 7 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02567994

    Tenelia Triple Combination Study

    Not yet reported Handok Inc. 201 participants Est. completion 2017-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02570672

    Metformin for Preventing Frailty in High-risk Older Adults

    Not yet reported The University of Texas Health Science Center at San Antonio 141 participants Est. completion 2024-02-07 1 site
    Other conditions: Frailty
    View official trial listing →
  • Completed NCT NCT02613897

    ESR-15-11293 - Saxa/Dapa, Safety and Efficacy Study

    Not yet reported The University of Texas Health Science Center at San Antonio 56 participants Est. completion 2018-06-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02627898

    Effect of Green Tea Extract on Arterial Stiffness in Type 2 Diabetes Mellitus

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2016-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02637037

    A Study to Assess the Bioequivalence of Dapagliflozin/Metformin XR Fixed-dose Combination Tablets in Healthy Subjects

    Not yet reported AstraZeneca 80 participants Est. completion 2016-04-07 1 site
    Other conditions: Bioequivalence, Fixed Dose Combination Tablets, Healthy Male and Female Subjects
    View official trial listing →
  • Completed NCT NCT02653599

    A Study to Evaluate Safety and Efficacy of TTP273 for 12 Weeks in Subjects With Type 2 Diabetes

    Not yet reported vTv Therapeutics 174 participants Est. completion 2017-01 30 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02681094

    A Multi-Center, Randomized, Double-Blind, Phase III Trial to Evaluate the Safety and Efficacy of Saxagliptin Co-administered With Dapagliflozin Compared to Saxagliptin or Dapagliflozin All Given as add-on Therapy to Metformin in Subject With Type 2 Diabetes

    Not yet reported AstraZeneca 905 participants Est. completion 2017-07-15 110 sites
    Type 2 diabetes Other conditions: Inadequate Glycaemic Control
    View official trial listing →
  • Status unknown NCT NCT02730741

    Study of the Efficacy and Tolerance of Oral Treatment With a Total Freeze-dried Culture of Lcr Restituo® Sachets (Lactobacillus Rhamnosus Lcr35®) on Intolerance to Metformin (Diarrhoea) in Patients With Diabetes Type 2

    Not yet reported Biose 60 participants 1 site
    Other conditions: Antidiarrhoea
    View official trial listing →
  • Completed NCT NCT02743260

    Drug Transporter Interaction Study PHENTRA_2015_KPUK

    Not yet reported University of Cologne 24 participants Est. completion 2017-12 1 site
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02744131

    OCP vs Metformin for Improvement in Clinical Symptoms and Metabolic Markers in Indian PCOS Women

    Not yet reported Kar Clinic & Hospital Pvt. Ltd. 100 participants Est. completion 2019-12 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02744976

    Coronary Artery Disease Progression in Patients With Prediabetes

    Not yet reported Pauls Stradins Clinical University Hospital 70 participants Est. completion 2021-09 1 site
    Cardiovascular disease Other conditions: Atherosclerosis, Prediabetic State
    View official trial listing →
  • Completed NCT NCT02755844

    Safety and Efficacy of Metronomic Cyclophosphamide, Metformin and Olaparib in Endometrial Cancer Patients

    Not yet reported, Not yet reported Hospices Civils de Lyon 35 participants Est. completion 2020-06 6 sites
    Other conditions: Recurrent Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT02793505

    Safety of Metformin in Pregnancy

    Centre Hospitalier Universitaire Vaudois 950 participants
    Other conditions: Pregnancy, Pregestational Diabetes, Polycystic Ovary Syndrom
    View official trial listing →
  • Completed NCT NCT02798172

    The Effect of Alogliptin on Pulmonary Function in Obese Patients With Type 2 Diabetes Inadequately Controlled by Metformin Monotherapy

    Not yet reported Fourth People's Hospital of Shenyang 81 participants Est. completion 2015-08
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02802215

    Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome

    Not yet reported, Not yet reported Ain Shams University 80 participants Est. completion 2016-09 1 site
    Other conditions: Polycystic Ovary Syndrome, Diabetes, Gestational
    View official trial listing →
  • Completed NCT NCT02805283

    Dapagliflozin Patient Satisfaction Survey

    AstraZeneca 653 participants Est. completion 2018-10-29 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02810132

    Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failure

    Not yet reported Aarhus University Hospital 36 participants Est. completion 2018-02-14 1 site
    Heart failure
    View official trial listing →
  • Completed NCT NCT02851095

    A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

    Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-11 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02866786

    The Effects of OCP and Metformin on Clinical, Hormonal, Metabolic and Ultrasonographic Characteristics in PCOS

    Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2017-08-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02911792

    Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With Hyperfiltration

    Not yet reported The University of Texas Health Science Center at San Antonio 72 participants Est. completion 2023-07-11 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02911948

    A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic Drugs

    Not yet reported Novo Nordisk A/S 210 participants Est. completion 2017-11-22 38 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02919345

    Assessment of Dapagliflozin Effect on Diabetic Endothelial Dysfunction of Brachial Artery

    Not yet reported University of Campinas, Brazil 98 participants Est. completion 2019-03 1 site
    Type 2 diabetesCardiovascular disease Other conditions: Carotid Artery Diseases
    View official trial listing →
  • Completed NCT NCT02920801

    Study About Effect of Saxagliptin on Circulating Endothelial Progenitor Cells and Endothelial Function in Newly Diagnosed Type 2 Diabetic Patients

    Not yet reported Shanghai Zhongshan Hospital 31 participants Est. completion 2015-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02931253

    Metformin as an Upstream Therapy in Atrial Fibrillation

    Not yet reported The Guthrie Clinic 6 participants Est. completion 2018-07-10 1 site
    Other conditions: Atrial Fibrillation
    View official trial listing →
  • Terminated NCT NCT02946996

    Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

    Not yet reported Medical University of South Carolina 41 participants Est. completion 2024-08-19 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT02949193

    Efficacy and Safety of Evogliptin add-on to Metformin in Patients With type2 Diabetes

    Not yet reported Dong-A ST Co., Ltd. 222 participants Est. completion 2015-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02951260

    The Effects of Metformin on Self-selected Exercise Intensity, Physical Fitness and Exercise-induced AMPK-activation

    Not yet reported Rigshospitalet, Denmark 15 participants Est. completion 2017-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03017833

    Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers

    Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2022-12-21 1 site
    Other conditions: Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory Neoplasm
    View official trial listing →
  • Status unknown NCT NCT03029390

    Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes

    Not yet reported University of Guadalajara 28 participants Est. completion 2023-12 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT03029702

    Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus

    Not yet reported Maisa N. Feghali, MD 54 participants Est. completion 2023-08-31 1 site
    Other conditions: Gestational Diabetes, Diabetes, Gestational, Pregnancy in Diabetes
    View official trial listing →
  • Completed NCT NCT03030300

    Remission Rate of Newly Diagnosed Type 2 Diabetes Outpatients Treated With Short-term Intensive Insulin Therapy

    Not yet reported Qianfoshan Hospital 170 participants Est. completion 2015-02 3 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03031821

    Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome

    Not yet reported Canadian Urologic Oncology Group 166 participants Est. completion 2023-11-24 16 sites
    Metabolic syndrome Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT03034941

    Short Term Weight Loss With Liraglutide and Metformin in Infertile Obese PCOS Patients

    Not yet reported University Medical Centre Ljubljana 35 participants Est. completion 2016-12 1 site
    Other conditions: Obesity, PCOS
    View official trial listing →
  • Completed NCT NCT03054519

    Improve PAD PERformance With METformin

    Not yet reported Northwestern University 202 participants Est. completion 2025-11-01 5 sites
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Completed NCT NCT03088631

    Metformin in Intracytoplasmic Sperm Injection Cycles

    Not yet reported Assiut University 320 participants Est. completion 2019-04-01 1 site
    Other conditions: Intracytoplasmatic Sperm Injection
    View official trial listing →
  • Completed NCT NCT03115112

    Safety and Efficacy of Bexagliflozin Compared to Sitagliptin as Add-on Therapy to Metformin in Type 2 Diabetes Subjects

    Not yet reported Theracos 386 participants Est. completion 2018-10-31 56 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03118713

    A Study to Evaluate the Renal Protective Effect (Urine Albumin-to-Creatinine Ratio (UACR)), Efficacy and Safety of Ipragliflozin in Type 2 Diabetes Mellitus Patients With Albuminuria

    Not yet reported Astellas Pharma Korea, Inc. 33 participants Est. completion 2018-12-12 8 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03122041

    Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type 2 Diabetes in Metformin Intolerant Obese Women With Polycystic Ovary Syndrome

    Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2016-11
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT03183752

    Insulin Resistance and Metformin Use on Volume of Benign Thyroid Nodules

    Not yet reported Hospital Universitário Clementino Fraga Filho 28 participants Est. completion 2019-04-17 1 site
    Other conditions: Thyroid Nodule, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT03192293

    Metformin and Simvastatin in Addition to Fulvestrant

    Not yet reported National University Hospital, Singapore 28 participants Est. completion 2019-01-20 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT03194945

    Effects of Sequential Treatment Based on Lina/MET After Short-term Intensive Insulin in Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 412 participants Est. completion 2022-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03204058

    Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 90 participants Est. completion 2017-02-23
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Completed NCT NCT03204071

    Locally Delivered Metformin and Aloe Vera for Treatment of Intrabody Defects in Chronic Periodontitis

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 90 participants Est. completion 2017-02
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Completed NCT NCT03207698

    PRF+1% MF for Class II Mandibular Furcation Defects

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 75 participants Est. completion 2016-05 1 site
    Other conditions: Furcation Defects
    View official trial listing →
  • Completed NCT NCT03208309

    Effect of Diacerein in the Metabolic Control of Patients With DM Type 2 and Secondary Failure to Metformin

    Not yet reported ANS Pharma 40 participants Est. completion 2015-12 3 sites
    Type 2 diabetes Other conditions: Complications of Diabetes Mellitus, Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03229057

    Comparing the Effects of Oral Contraceptive Pills Versus Metformin

    Not yet reported Anuja Dokras 240 participants Est. completion 2024-07-15 2 sites
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT03236740

    OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS

    Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2018-03-15 1 site
    Other conditions: PCOS
    View official trial listing →
  • Status unknown NCT NCT03238495

    Randomized Trial of Neo-adjuvant Chemotherapy With or Without Metformin for HER2 Positive Operable Breast Cancer

    Not yet reported Qamar Khan 100 participants Est. completion 2023-06-01 6 sites
    Other conditions: HER2-positive Breast Cancer
    View official trial listing →
  • Completed NCT NCT03259789

    Safety and Efficacy of Bexagliflozin Compared to Placebo as Add-on Therapy to Metformin in Type 2 Diabetes Subjects

    Not yet reported Theracos 351 participants Est. completion 2019-01-23 43 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03320694

    Comparison of Metformin and Insulin for Management of Gestational Diabetes Mellitus

    Not yet reported Services Institute of Medical Sciences, Pakistan 278 participants Est. completion 2017-06-30 1 site
    Other conditions: Gestational Diabetes Mellitus in Pregnancy
    View official trial listing →
  • Terminated NCT NCT03331861

    Metformin in Heart Failure Without Diabetes

    Not yet reported Columbia University 6 participants Est. completion 2021-08-20 1 site Stand-alone
    Heart failure
    View official trial listing →
  • Status unknown NCT NCT03336840

    Effect of Metformin and Probiotics in Reproductive-aged Patients With Polycystic Ovary Syndrome

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 90 participants Est. completion 2019-06 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT03355014

    BE Study of the Combinations of Gemigliptin/Metformin HCl Extended Release 50/1000mg(25/500mg x 2 Tablets) in Comparison to Each Component Administered Alone

    Not yet reported LG Chem 70 participants Est. completion 2018-01-12 1 site
    Other conditions: Healthy Male Volunteers
    View official trial listing →
  • Completed NCT NCT03355469

    Exercise Dose and Metformin for Vascular Health in Metabolic Syndrome

    Not yet reported, Not yet reported Rutgers University 91 participants Est. completion 2024-05-23 1 site
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT03359590

    Sitagliptin and the Risk for Hypoglycaemia in Type 2 Diabetes Patients

    Not yet reported Profil Institut für Stoffwechselforschung GmbH 20 participants Est. completion 2019-07-17 1 site
    Other conditions: Pharmacological Action
    View official trial listing →
  • Completed NCT NCT03359681

    Metformin Treatment for Colon Cancer

    Not yet reported Zealand University Hospital 48 participants Est. completion 2021-10-04 1 site
    Other conditions: Colon Cancer
    View official trial listing →
  • Completed NCT NCT03361878

    Pharmacokinetics of Metformin Intolerance

    Not yet reported NHS Tayside 20 participants Est. completion 2016-05-05
    Type 2 diabetes Other conditions: Metformin Adverse Reaction
    View official trial listing →
  • Status unknown NCT NCT03383068

    Research of Intensive Metabolic Intervention Before Pregnancy in PCOS

    Not yet reported RenJi Hospital 160 participants Est. completion 2020-06-30 1 site
    Prediabetes Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT03398356

    Metformin and Its Impact on the Substances Associated With NO Production in Prediabetes Patients.

    Not yet reported Wroclaw Medical University 47 participants Est. completion 2019-04-30 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT03451734

    Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients

    Central South University 2000 participants Est. completion 2021-06-30 1 site
    Metabolic syndrome Other conditions: Schizophrenia
    View official trial listing →
  • Completed NCT NCT03467763

    Trial of an Intervention to Improve Metformin Persistence and Adherence

    Not yet reported Weill Medical College of Cornell University 13 participants Est. completion 2020-08-01 1 site
    Other conditions: Metformin Adverse Reaction, Tolerance
    View official trial listing →
  • Terminated NCT NCT03477162

    Metformin Pharmacology in Human Cancers: A Proof of Principle Study

    Not yet reported Dartmouth-Hitchcock Medical Center 18 participants Est. completion 2021-11-30 1 site
    Other conditions: Thoracic Neoplasm
    View official trial listing →
  • Status unknown NCT NCT03513874

    Metformin Plus Insulin on Non-obese Autoimmune Diabetes

    Not yet reported Second Xiangya Hospital of Central South University 15 participants Est. completion 2021-04-01 1 site
    Other conditions: Type 1 Diabetes Mellitus, Autoimmune Diabetes
    View official trial listing →
  • Completed NCT NCT03552991

    Effects of Dietary Fiber on Glucose Control in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Samsung Medical Center 14 participants Est. completion 2018-05-31
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03566225

    Pioglitazone Versus Metformin as First Treatment in Infertile Women With Polycystic Ovary Syndrome

    Not yet reported Ain Shams University 400 participants Est. completion 2021-03-30 1 site
    Other conditions: Pioglitazone
    View official trial listing →
  • Completed NCT NCT03583385

    Glucophage® Extended Release (XR) 750 Milligram (mg) Indonesia Bioequivalence (BE) Study

    Not yet reported Merck KGaA, Darmstadt, Germany 48 participants Est. completion 2018-10-05 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03593135

    Effect of Apple Cider Vinegar in Type 2 Diabetics

    Not yet reported Sheikh Zayed Federal Postgraduate Medical Institute 126 participants Est. completion 2017-11-14 1 site
    Other conditions: Randomized Controlled Trial, Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03593707

    Drug-Drug Interaction Study to Evaluate the Effect of PF-06865571 on Metformin Pharmacokinetics

    Not yet reported Pfizer 18 participants Est. completion 2019-02-13 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT03617458

    Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension

    Not yet reported Vanderbilt University Medical Center 73 participants Est. completion 2025-08-19 1 site
    Other conditions: Pulmonary Artery Hypertension
    View official trial listing →
  • Completed NCT NCT03618654

    Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 38 participants Est. completion 2022-12-07 1 site
    Other conditions: Head and Neck Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT03670043

    Tolerance & Responsiveness Improvement for Metformin (TRIM)

    Not yet reported West Side Institute for Science and Education 29 participants Est. completion 2021-08-15 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03686722

    Effect of Co-administration of Metformin and Daclatasvir on the Pharmacokinetis and Pharmacodynamics of Metformin

    Not yet reported Mohamed Raslan 20 participants Est. completion 2017-12-06 1 site
    Type 2 diabetes Other conditions: Hepatitis C, Drug Interactions
    View official trial listing →
  • Completed NCT NCT03710343

    Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study

    Not yet reported Holland Bloorview Kids Rehabilitation Hospital 3 participants Est. completion 2025-04-24 2 sites
    Other conditions: Cerebral Palsy
    View official trial listing →
  • Completed NCT NCT03711682

    Reducing Plasma Glucose Effect of Cinnamon in Type 2 Diabetic Patients in the Municipality of Comasagua

    Not yet reported, Not yet reported Universidad Dr. José Matías Delgado 30 participants Est. completion 2018-05-23 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03713801

    Impact of Metformin on Immunity

    Not yet reported The University of Texas Health Science Center at San Antonio 18 participants Est. completion 2024-07-16 1 site
    Other conditions: Aging, Vaccine Response Impaired
    View official trial listing →
  • Completed NCT NCT03733132

    Metformin Effect on Brain Function in Insulin Resistant Elderly People

    Not yet reported Mayo Clinic 40 participants Est. completion 2023-04-05 1 site
    Other conditions: Insulin Resistance, Obesity, Obesity, Abdominal
    View official trial listing →
  • Completed NCT NCT03746106

    The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine

    Not yet reported University of California, San Francisco 7 participants Est. completion 2023-08-10 1 site
    Other conditions: Vitamin B1 Deficiency, Thiamine Deficiency
    View official trial listing →
  • Completed NCT NCT03787043

    A Study to Evaluate the Effect of Food on Fixed-Dose Combination of MP-513 10 mg and Metformin XR 750 mg

    Not yet reported Handok Inc. 30 participants Est. completion 2014-06 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT03794336

    Efficacy and Safety of Alogliptin vs. Acarbose in Chinese Type 2 Diabetes Mellitus (T2DM) Patients With High CV Risk or CHD Treated With Aspirin and Inadequately Controlled With Metformin Monotherapy or Drug Naive

    Not yet reported Sanofi 1293 participants Est. completion 2020-12-14 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03798054

    Evaluation of Insulin Glargine/Lixisenatide Fixed Ratio Combination in Patients With Type 2 Diabetes Insufficiently Controlled With Oral Antidiabetic Drug(s)

    Not yet reported Sanofi 878 participants Est. completion 2021-03-01 79 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03800602

    Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

    Not yet reported Emory University 29 participants Est. completion 2021-09-04 3 sites
    Obstructive sleep apnea Other conditions: Colorectal Adenocarcinoma, Refractory Colorectal Carcinoma, Stage IV Colorectal Cancer, Stage IVA Colorectal Cancer, Stage IVB Colorectal Cancer, Stage IVC Colorectal Cancer, Colorectal Cancer Metastatic
    View official trial listing →
  • Completed NCT NCT03826641

    A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HCP1801 in Healthy Subjects

    Not yet reported Hanmi Pharmaceutical Company Limited 85 participants Est. completion 2019-04-16 1 site
    Other conditions: Healthy
    View official trial listing →
  • Active, not recruiting NCT NCT03889795

    Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors

    Not yet reported Danae Hamouda, MD 15 participants Est. completion 2027-12-30 1 site
    Other conditions: Advanced Pancreatic Cancer, Advanced Solid Tumor
    View official trial listing →
  • Withdrawn NCT NCT03905941

    Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age

    Not yet reported University of Virginia Est. completion 2024-11-25 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT03934021

    Gut Microbiota in Acute Stroke Patients

    Chinese University of Hong Kong 120 participants Est. completion 2024-08-30 1 site
    Cardiovascular disease Other conditions: Microbiome, Atherosclerosis Cerebral
    View official trial listing →
  • Completed NCT NCT03951805

    A Research Study to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine in People With Type 2 Diabetes Who Have Not Used Insulin Before

    Not yet reported Novo Nordisk A/S 205 participants Est. completion 2020-01-17 43 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03970434

    Drug Concentration of Metformin According to Sampling Method

    Not yet reported Chonbuk National University Hospital 20 participants Est. completion 2019-06-05 1 site
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT03972982

    Effects of Structured Simplified Short-term Intensive Insulin Therapy on Long-term Glycemic Remission

    Not yet reported Sun Yat-sen University 330 participants Est. completion 2022-12-31 1 site
    Type 2 diabetes Other conditions: Simplified Short-term Intensive Insulin Therapy, Glycemic Remission
    View official trial listing →
  • Completed NCT NCT03987919

    A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 1879 participants Est. completion 2021-02-15 127 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03994744

    Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLC

    Not yet reported Hunan Cancer Hospital 68 participants Est. completion 2022-07-01 1 site
    Other conditions: Small-cell Lung Cancer, Small Cell Lung Carcinoma, Small Cell Lung Cancer Recurrent, Small Cell Lung Cancer Extensive Stage
    View official trial listing →
  • Completed NCT NCT04009603

    Comparison of Probiotics, Metformin & Their Combination Therapy in the Treatment of PCOS

    Not yet reported Ziauddin University 78 participants Est. completion 2020-01-28 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04018105

    Influence of Preprandial Metformin Administration on Carbohydrate Absorption

    Not yet reported University Hospital, Lille 1 participants Est. completion 2025-04-05
    PrediabetesType 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04029272

    Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients

    Not yet reported Peking Union Medical College Hospital 80 participants Est. completion 2020-12-31 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04029480

    Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

    Not yet reported Merck Sharp & Dohme LLC 166 participants Est. completion 2025-04-11 104 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04033107

    High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors

    Not yet reported Zhongnan Hospital 30 participants Est. completion 2024-12 1 site
    Other conditions: Hepatocellular Cancer, Pancreatic Cancer, Gastric Cancer, Colorectal Cancer
    View official trial listing →
  • Completed NCT NCT04043221

    Long Term Metformin in Women With Polycystic Ovary Syndrome

    University Medical Centre Ljubljana 180 participants Est. completion 2019-01-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04068246

    The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Rheumatoid Arthritis Patients

    Not yet reported, Not yet reported Sadat City University 120 participants Est. completion 2021-02-28 1 site
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT04070794

    Food-effect Bioavailability of Fixed Dose Combination Zemimet® SR Tab. 50/1000 mg Under Fed and Fasting Conditions

    Not yet reported LG Chem 24 participants Est. completion 2019-12-30
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04088448

    The Antidiabetic Metformin as a Novel Adjunct to Antidepressants in Major Depressive Disorder Patients

    Not yet reported, Not yet reported Sadat City University 80 participants Est. completion 2020-06-01 1 site
    Other conditions: Major Depressive Disorder
    View official trial listing →
  • Active, not recruiting NCT NCT04088851

    "Hepatic Substrate Flux Rates in Type 2 Diabetes"

    Not yet reported German Diabetes Center 23 participants Est. completion 2025-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04090580

    Impact on Glycemic Variability in Newly Onset T2DM Patients Initiating Dapagliflozin Plus Metformin Versus Metformin Alone

    Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 88 participants Est. completion 2021-03-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04134650

    Effect of Low Dose Combination of Linagliptin + Metformin to Prevent Diabetes

    Not yet reported Universidad de Guanajuato 34 participants Est. completion 2020-07-01 1 site
    Other conditions: Prediabetic State, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT04143282

    Evaluation of the Effect of Metformin on Metastatic Breast Cancer as Adjuvant Treatment

    Not yet reported Hager salah el din 250 participants Est. completion 2020-06-30 1 site
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Completed NCT NCT04170439

    Added Value of N Acetyle Cysteine to Clomiphene Citrate in PCO

    Not yet reported Aljazeera Hospital 108 participants Est. completion 2020-05-15 2 sites
    Other conditions: PCO
    View official trial listing →
  • Terminated NCT NCT04170959

    The Addition of Metformin to Definitive Radiotherapy in Patients With Stage III NSCLC

    Not yet reported ethisch.comite@uza.be 3 participants Est. completion 2021-01-08 1 site
    Other conditions: Carcinoma, Non-Small-Cell Lung
    View official trial listing →
  • Completed NCT NCT04192292

    Study of Sulphonylurea Synergy With DPP4 Inhibitors

    Not yet reported University of Dundee 30 participants Est. completion 2020-12-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04207944

    The Prevention of Progression to Pancreatic Cancer Trial (The 3P-C Trial)

    Not yet reported Duke University 100 participants Est. completion 2026-10-31 4 sites
    Other conditions: IPMN, IPMN, Pancreatic
    View official trial listing →
  • Completed NCT NCT04209075

    Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 6 participants Est. completion 2021-07-15 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT04221750

    Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors

    Not yet reported VA Office of Research and Development 114 participants Est. completion 2025-07-31 1 site Stand-alone
    Other conditions: Frailty, Sarcopenic Obesity, Aging
    View official trial listing →
  • Completed NCT NCT04268394

    A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

    Not yet reported Celgene 48 participants Est. completion 2021-06-02 1 site
    Other conditions: Healthy Volunteer
    View official trial listing →
  • Completed NCT NCT04283318

    Prolonged Fasting on Glucose Metabolism and Hormonal Regulation in Healthy, Obese and Subjects With Type 2 Diabetes

    Not yet reported Medical University of Graz 80 participants Est. completion 2022-02-28 1 site
    Type 2 diabetes Other conditions: Healthy, Obesity, Type 1 Diabetes
    View official trial listing →
  • Status unknown NCT NCT04284722

    Perioperative Continuation of Metformin Therapy in Patients With Typ 2 Diabetes Mellitus Undergoing Non-cardiac Surgery

    Not yet reported Kepler University Hospital 400 participants Est. completion 2021-04
    Type 2 diabetes Other conditions: Hyperglycemia, Metformin, Hyperlactatemia
    View official trial listing →
  • Completed NCT NCT04300790

    Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients

    Not yet reported MedSIR 69 participants Est. completion 2025-03-16 19 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT04343872

    Preventing Diabetes in the Deep South: Extending Partnerships and Adapting Interventions to Reach Rural Communities at High Risk.

    Not yet reported University of Alabama at Birmingham 36 participants Est. completion 2022-12-31 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT04377321

    Colchicine Has Anti-diabetic Effect

    Ministry of Health and Population, Egypt 150 participants Est. completion 2020-05-02 1 site
    Other conditions: Treatment Adherence
    View official trial listing →
  • Status unknown NCT NCT04390295

    Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 450 participants Est. completion 2020-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04407650

    Ursodeoxycholic Acid vs Metformin in Gestational Diabetes Mellitus

    Not yet reported King's College London 64 participants Est. completion 2025-05-31 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Status unknown NCT NCT04485845

    Metformin Versus Vildagliptin in Reducing Risk of Metabolic Syndrome Complications Progression

    Not yet reported Cairo University 39 participants Est. completion 2020-09-30 1 site
    Metabolic syndrome Other conditions: Diabete Type 2, Kidney Insufficiency
    View official trial listing →
  • Active, not recruiting NCT NCT04511416

    Preventing Cognitive Decline with Metformin

    Not yet reported Garvan Institute of Medical Research 242 participants Est. completion 2027-12 1 site
    Other conditions: Cognitive Decline
    View official trial listing →
  • Completed NCT NCT04549415

    The Influence of Metformin on Chronic Heart Failure Clinical Course in Patients With Prediabetes

    Not yet reported National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov 97 participants Est. completion 2019-11-15 1 site
    Heart failureCardiovascular diseasePrediabetes
    View official trial listing →
  • Completed NCT NCT04625985

    Metformin Glycinate, Treatment of Patients With COVID-19 and Severe Acute Respiratory Syndrome Secondary to SARS-CoV-2.

    Not yet reported Laboratorios Silanes S.A. de C.V. 20 participants Est. completion 2021-03-18 1 site
    Other conditions: Severe Acute Respiratory Syndrome Coronavirus 2
    View official trial listing →
  • Completed NCT NCT04639492

    Postbiotic MBS and Metformin Combination in Patients With T2DM

    Not yet reported Microbio Co Ltd 14 participants Est. completion 2022-09-23 1 site
    Other conditions: Type-II Diabetes
    View official trial listing →
  • Status unknown NCT NCT04672031

    Glycemic Targets for Pregnant Women With GDM and T2DM

    Not yet reported University of Southern California 120 participants Est. completion 2023-07 1 site
    Type 2 diabetes Other conditions: Diabetes Mellitus in Pregnancy, Diabetes, Gestational
    View official trial listing →
  • Status unknown NCT NCT04780854

    Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN)

    Not yet reported Cairo University 68 participants Est. completion 2022-07 1 site
    Other conditions: Chemotherapy-induced Peripheral Neuropathy
    View official trial listing →
  • Status unknown NCT NCT04796428

    GliflOzin in eLderly Diabetic patiENts: A praGmatic Intraclass Evaluation Trial

    Not yet reported Center for Outcomes Research and Clinical Epidemiology, Italy 1167 participants Est. completion 2023-12-31
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04817215

    Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus

    Not yet reported King Hamad University Hospital, Bahrain 608 participants Est. completion 2022-07
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04826692

    TEsting METformin Against Cognitive Decline in HD

    Not yet reported Instituto de Investigacion Sanitaria La Fe 60 participants Est. completion 2025-06-10 9 sites
    Other conditions: Huntington Disease
    View official trial listing →
  • Withdrawn NCT NCT04839237

    The Effect and the Pharmacogenomics Study of Liraglutide in Obese Patients

    Not yet reported Xiangya Hospital of Central South University Est. completion 2021-12-01 1 site
    Other conditions: Obesity
    View official trial listing →
  • Status unknown NCT NCT04855513

    Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial

    Not yet reported Hamad Medical Corporation 414 participants Est. completion 2023-12-30 1 site
    Other conditions: Preeclampsia, Preeclampsia Severe, High Risk Pregnancy, Eclampsia
    View official trial listing →
  • Completed NCT NCT04862390

    Incidence of Hypoglycemia in Pregnant Ladies With or Without Gestational Diabetes Fasting Ramadan

    King Abdullah International Medical Research Center 30 participants Est. completion 2021-08-01 1 site
    Other conditions: Pregnancy in Diabetic
    View official trial listing →
  • Status unknown NCT NCT04882332

    Metformin Usage Index and Vitamin B12 Status in Egyptian Type 2 Diabetic Patients

    Cairo University 108 participants Est. completion 2022-10 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT04899349

    Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and Fulvestrant

    Not yet reported Novartis Pharmaceuticals 2 participants Est. completion 2023-05-10 2 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT04907708

    Comparative Effects of Metformin and Insulin on Stereological Studies and Immunohistochemistry of Placenta

    Not yet reported University of Karachi 156 participants Est. completion 2019-08-07 1 site
    Other conditions: Diabetes Mellitus Arising in Pregnancy, Insulin-Requiring, Diabetes Mellitus in Pregnancy
    View official trial listing →
  • Active, not recruiting NCT NCT04925063

    The Effect of Metformin in Patients With Newly Diagnosed mHSPC

    Not yet reported Sun Yat-sen University 266 participants Est. completion 2027-01-31 1 site
    Other conditions: Metastatic Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT04930471

    Steroid and Behaviour Changes Under Metformin

    Insel Gruppe AG, University Hospital Bern 45 participants Est. completion 2023-12 1 site
    Other conditions: Autistic Disorder
    View official trial listing →
  • Status unknown NCT NCT04962841

    Nutraceuticals and Drug Treatment in Frail Older Adults

    University of Campania Luigi Vanvitelli 485 participants Est. completion 2023-04-01 1 site
    Other conditions: Frailty
    View official trial listing →
  • Completed NCT NCT04973891

    CANA/Met in Non-diabetic Women With PCOS

    Not yet reported, Not yet reported Shengjing Hospital 52 participants Est. completion 2022-03-08 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04979130

    Comparing Semaglutide Versus Placebo on Intestinal Barrier Function in Type 2 Diabetes Mellitus (SIB)

    Not yet reported University of Colorado, Denver 69 participants Est. completion 2024-10-16 1 site
    Type 2 diabetes Other conditions: Chronic Inflammation, Intestinal Permeability
    View official trial listing →
  • Completed NCT NCT05013112

    Ameliorating Metabolic Profiling After Kidney Transplantation (AMPKT)

    Not yet reported West China Hospital 105 participants Est. completion 2025-12-31 1 site
    Other conditions: Kidney Transplantation, Metabolic Disorder, Metformin, Empagliflozin
    View official trial listing →
  • Active, not recruiting NCT NCT05040087

    Changing the Natural History of Type 2 Diabetes ("CHANGE" Study)

    Not yet reported Foundation for Atlanta Veterans Education and Research, Inc. 127 participants Est. completion 2028-06-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05042505

    Effect of Dapagliflozin vs Sitagliptin on Liver Fat Accumulation and Body Composition in Patients With Diabetes Mellitus and Liver Transplantation

    Not yet reported Medanta, The Medicity, India 100 participants Est. completion 2026-02-27 1 site
    Other conditions: Diabetes Mellitus, Liver Transplant; Complications
    View official trial listing →
  • Withdrawn NCT NCT05102071

    Clinical Outcomes and Healthcare Cost and Resource Utilization (HCRU) in Patients With Type 2 Diabetes and Cardiovascular Disease on 2nd Line Empagliflozin Versus 2nd Line Sulfonylureas

    Boehringer Ingelheim Est. completion 2022-06-15 1 site
    Type 2 diabetesCardiovascular disease
    View official trial listing →
  • Completed NCT NCT05164523

    The Effect of SGLT2 Inhibitors on Heart Rate Variability and BDNF Levels in Patients With Type 2 Diabetes

    Goztepe Training and Research Hospital 64 participants Est. completion 2022-12-30 1 site
    Type 2 diabetes Other conditions: Heart Rate Variability
    View official trial listing →
  • Suspended NCT NCT05183204

    Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma

    Not yet reported Weill Medical College of Cornell University 33 participants Est. completion 2026-06 1 site
    Other conditions: Glioblastoma
    View official trial listing →
  • Status unknown NCT NCT05261997

    Endotherapy for Painless Chronic Pancreatitis

    Not yet reported Changhai Hospital 60 participants Est. completion 2023-11 1 site
    Other conditions: Pancreatitis, Chronic, Exocrine Pancreatic Insufficiency, Abdominal Pain, Cholangiopancreatography, Endoscopic Retrograde
    View official trial listing →
  • Active, not recruiting NCT NCT05275608

    Effects of VLCKD in Metabolic Syndrome

    Not yet reported Azienda Ospedaliero Universitaria Maggiore della Carita 40 participants Est. completion 2026-12 1 site
    Type 2 diabetesMetabolic syndrome Other conditions: Non-alcoholic Fatty Liver Disease, Obesity
    View official trial listing →
  • Completed NCT NCT05288153

    Metformin Efficacy and Safety for Gastric Intestinal Metaplasia

    Not yet reported Xijing Hospital of Digestive Diseases 140 participants Est. completion 2023-10-31 2 sites
    Other conditions: Gastric Intestinal Metaplasia
    View official trial listing →
  • Completed NCT NCT05313529

    LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 396 participants Est. completion 2026-07-01 5 sites
    Type 2 diabetes Other conditions: Mild Cognitive Impairment
    View official trial listing →
  • Completed NCT NCT05349474

    Metformin Treatment in Progressive Multiple Sclerosis

    Not yet reported University of California, Los Angeles 23 participants Est. completion 2025-05-30 1 site
    Other conditions: Secondary Progressive Multiple Sclerosis, Primary Progressive Multiple Sclerosis
    View official trial listing →
  • Completed NCT NCT05365451

    Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters

    Not yet reported Washington State University 16 participants Est. completion 2023-07-22 1 site
    Other conditions: Interaction, Endogenous Biomarkers
    View official trial listing →
  • Completed NCT NCT05369793

    Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic Neuropathy

    Not yet reported Tanta University 60 participants Est. completion 2023-10-10 1 site
    Type 2 diabetes Other conditions: Diabetic Neuropathies
    View official trial listing →
  • Completed NCT NCT05376969

    Evaluate the Long Term Safety and Efficacy of DWP16001 add-on to Metformin in Patients With T2DM Inadequately Controlled on Metformin

    Not yet reported Daewoong Pharmaceutical Co. LTD. 159 participants Est. completion 2022-05-16 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05395377

    Preventing Diabetes

    Not yet reported Geisinger Clinic 84 participants Est. completion 2021-11-16 1 site
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT05396378

    Early Recovery After Cesarean Delivery - Maternal Glucose Homeostasis Following Preoperative Glucose Dose

    Women's Hospital HUS 150 participants Est. completion 2023-12-31 1 site
    Other conditions: Gestational Diabetes, Cesarean Section Complications
    View official trial listing →
  • Status unknown NCT NCT05418452

    Efficacy of 1% Metformin Gel Mixed With PRF in Augmenting Narrow Ridge

    Not yet reported Al-Azhar University 2 participants Est. completion 2023-06-15 1 site
    Other conditions: Horizontal Ridge Deficiency
    View official trial listing →
  • Status unknown NCT NCT05422092

    Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease

    Not yet reported First Affiliated Hospital Xi'an Jiaotong University 80 participants Est. completion 2023-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05504239

    Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin and Metformin

    Not yet reported Handok Inc. 235 participants Est. completion 2024-04-23 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05505994

    The Efficacy and Safety of DWP16001 in Combination With Metformin in T2DM Patients Inadequately Controlled on Metformin

    Not yet reported Daewoong Pharmaceutical Co. LTD. 340 participants Est. completion 2024-09 1 site
    Type 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease, Endocrine System Diseases
    View official trial listing →
  • Status unknown NCT NCT05519813

    Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.

    Not yet reported Bing He 60 participants Est. completion 2023-03-20 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT05526690

    Study to Evaluate the Effect of CIN-107 on the Pharmacokinetics of the MATE Substrate, Metformin, in Healthy Subjects

    Not yet reported AstraZeneca 27 participants Est. completion 2020-12-12 1 site
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT05542420

    A Research Study, Looking at the Characterization of Treatment Intensified (Add on to Metformin) Real-world Adult Population With Type 2 Diabetes Mellitus in India, Pakistan and Thailand.

    Novo Nordisk A/S 3000 participants Est. completion 2023-04-20 3 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05572060

    Effect of Metformin Use on Mortality in Diabetic and Non Diabetic Patients With Sepsis and Septic Shock.

    Not yet reported Assiut University 75 participants Est. completion 2025-01-31
    Other conditions: Septic Shock
    View official trial listing →
  • Withdrawn NCT NCT05580250

    A Study of LY3526318 in Healthy Male Japanese Participants

    Not yet reported Eli Lilly and Company Est. completion 2022-12 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05615467

    A Study of Effect of LY3556050 on Metformin in Healthy Participants

    Not yet reported Eli Lilly and Company 18 participants Est. completion 2022-12-27 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05628584

    High FODMAP Diet With Metformin in preDM

    Not yet reported Elaine Chow 26 participants Est. completion 2023-10-15 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT05638893

    Metformin as Adjuvant Therapy in Obese Knee Osteoarthritis Patients

    Not yet reported, Not yet reported Tanta University 50 participants Est. completion 2022-04-15 1 site
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT05657613

    Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects

    Not yet reported CTI BioPharma 60 participants Est. completion 2023-06-08 1 site
    Other conditions: Drug Interactions
    View official trial listing →
  • Status unknown NCT NCT05663736

    Effect of Gemigliptin Versus Glimepiride on Cardiac Diastolic Function in Patients With Type 2 Diabetes

    Not yet reported Seoul National University Bundang Hospital 80 participants Est. completion 2023-12-31 1 site
    Other conditions: Ejection Fraction
    View official trial listing →
  • Status unknown NCT NCT05759897

    A 16 Week Study of HRS-7535 in Adults With Type 2 Diabetes Mellitus

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 180 participants Est. completion 2024-01-04
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05802212

    Effect of Metformin on Patients With Polycystic Ovary Syndrome

    Not yet reported Peking University Third Hospital 77 participants Est. completion 2023-05-01 1 site
    Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
    View official trial listing →
  • Status unknown NCT NCT05852639

    Fetal CPR at Term for Prediction of Adverse Neonatal Outcome in Pregnancies Complicated by GDM

    Cairo University 260 participants Est. completion 2024-04 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT05874167

    A Pharmacokinetic Study of DW6013 (FDC of Linagliptin and Metformin) in Healthy Adult Volunteers

    Not yet reported Dong Wha Pharmaceutical Co. Ltd. 50 participants Est. completion 2022-10-11 1 site
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT05981742

    Effects of Combined Metformin and Cabergoline in Comparison With Metformin Only Therapy on Ovarian and Hormonal Activities in Iraqi Patients With PCOS

    Not yet reported Al-Rasheed University College 75 participants Est. completion 2023-03-31 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT06010992

    Nitazoxanide as Adjuvant Therapy in Type 2 Diabetes Mellitus

    Not yet reported Tanta University 70 participants Est. completion 2025-01-01 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06065540

    A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor

    Not yet reported Novo Nordisk A/S 2734 participants Est. completion 2026-01-06 405 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06068686

    Vildagliptin Versus Glimepiride in Type 2 Diabetic Patients

    Not yet reported Damanhour University 70 participants Est. completion 2024-12-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT06083675

    Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S Est. completion 2027-05-28 100 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT06100822

    Managing Chronic Tendon Pain by Metformin

    Not yet reported James Wang 21 participants Est. completion 2026-08-24 1 site
    Other conditions: Tendinopathy, Chronic Pain, Achilles Tendinopathy
    View official trial listing →
  • Completed NCT NCT06124495

    Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.

    Not yet reported Galenicum Health 58 participants Est. completion 2023-02-13 1 site
    Type 2 diabetes Other conditions: Bioequivalence
    View official trial listing →
  • Status unknown NCT NCT06127433

    The Effect of Short-term Insulin Intensive Therapy Based on the Application of Insulin Pump and Real-time Dynamic Glucose Monitoring Technology on Reversing the Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 210 participants Est. completion 2024-12-30 1 site
    Other conditions: Insulin Pump，Continuous Glucose Monitoring Technology
    View official trial listing →
  • Status unknown NCT NCT06140485

    A Trial to Investigate the Efficacy and Safety of NW Low-Glu® in Patients With Type II Diabetes Mellitus

    Not yet reported Natural Wellness Egypt 400 participants Est. completion 2025-10
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06161844

    Efficacy and Safety of Semaglutide Injection (HD1916) in Patients With Type 2 Diabetes Mellitus

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 506 participants Est. completion 2025-05-14 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06181422

    Metformin and Lactoferrin in Sepsis in Icu

    Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2024-06-09 1 site
    Other conditions: Sepsis
    View official trial listing →
  • Completed NCT NCT06204107

    A Clinical Trial to Evaluate the Food Effect on Pharmacokinetic Profiles and Safety of CKD-379

    Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2023-12-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06217887

    Efficacy Comparison of Polyethylene Glycol Loxenatide and Gliclazide on the Brain Function in T2DM Patients

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 58 participants Est. completion 2024-06 1 site
    Type 2 diabetes Other conditions: Cognitive Function Abnormal
    View official trial listing →
  • Completed NCT NCT06244550

    Clinical Trials Using HepatoKeeper Herbal Essentials to Treat Non-alcoholic Fatty Liver Disease and Metabolic Factors

    Not yet reported Taipei City Hospital 60 participants Est. completion 2023-06-13 1 site
    Other conditions: Non-alcoholic Fatty Liver Disease, Liver Fibrosis, Liver Injury
    View official trial listing →
  • Active, not recruiting NCT NCT06257966

    A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Dulaglutide in Combination Therapy Diabetes Mellitus Type 2 Patients With Metformin

    Not yet reported Beijing Dongfang Biotech Co., Ltd. 600 participants Est. completion 2026-11-30 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT06260722

    Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)

    Not yet reported Eli Lilly and Company 1250 participants Est. completion 2027-01 77 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT06296836

    Effect of Continuing Versus Holding Metformin During Hospitalizations.

    Not yet reported University of Illinois at Chicago 22 participants Est. completion 2026-04-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT06297603

    Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

    Not yet reported Eli Lilly and Company 320 participants Est. completion 2026-11 76 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06327815

    Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM

    Not yet reported AstraZeneca 633 participants Est. completion 2025-06-30 35 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06357273

    The Effect of White Tea Consumption on Obesity

    Recep Tayyip Erdogan University 91 participants Est. completion 2023-12-15 1 site
    Other conditions: Obesity, Obesity; Endocrine, Obesity Adult Onset
    View official trial listing →
  • Completed NCT NCT06416800

    A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants

    Not yet reported Incyte Corporation 71 participants Est. completion 2025-01-15 1 site
    Other conditions: Healthy Participants
    View official trial listing →
  • Enrolling by invitation NCT NCT06429007

    A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury

    Not yet reported Boston Children's Hospital 30 participants Est. completion 2029-03-01 1 site
    Other conditions: Hypoxic-Ischemic Encephalopathy, HIE, Neurodevelopment, Infant Development
    View official trial listing →
  • Completed NCT NCT06450262

    Bioequivalence Study to Compare Empagliflozin/ Metformin HCl 12.5mg/1000mg Film-coated Tablets

    Not yet reported Humanis Saglık Anonim Sirketi 36 participants Est. completion 2024-03-05 1 site
    Other conditions: Type2diabetes
    View official trial listing →
  • Completed NCT NCT06476730

    Telerehabilitation Exercise: Effects on Maternal Psychological Health and Delivery Outcomes

    Not yet reported Riphah International University 62 participants Est. completion 2025-05-10 2 sites
    Other conditions: Gestational Diabetes Mellitus in Pregnancy, Gestational Diabetes, Maternal Psychological Distress
    View official trial listing →
  • Completed NCT NCT06479434

    Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls

    Not yet reported Aga Khan University 110 participants Est. completion 2025-10-02 1 site
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Withdrawn NCT NCT06490874

    Continuous Glucose Monitoring (CGM) Substudy of the DECIDE RCT

    Ohio State University Est. completion 2030-12 4 sites
    Other conditions: Gestational Diabetes Mellitus, Pregnancy, High Risk
    View official trial listing →
  • Completed NCT NCT06504862

    A Study in Healthy Men to Test Whether Zongertinib Influences the Amount of 4 Other Medicines (Dabigatran, Rosuvastatin, Metformin, and Furosemide) in the Blood

    Not yet reported Boehringer Ingelheim 32 participants Est. completion 2024-12-18 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT06523595

    Evaluation of the Pharmacokinetic Drug-drug Interactions Between VX-993 and Metformin in Healthy Adults

    Not yet reported Vertex Pharmaceuticals Incorporated 31 participants Est. completion 2024-12-31 1 site
    Other conditions: Pain
    View official trial listing →
  • Status unknown NCT NCT06545994

    A Prospective Cohort Study on the Serum Kisspeptin Levels Throughout Pregnancy in PCOS

    Fudan University 180 participants Est. completion 2026-06-30 1 site
    Other conditions: Polycystic Ovary Syndrome, Pregnancy Complications
    View official trial listing →
  • Completed NCT NCT06589765

    A Study of HRS-7535 Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequately Controlled With Metformin

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 810 participants Est. completion 2026-05-29 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT06611904

    The Effect of Combined Dulaglutide and Dapagliflozin Treatment vs DPP-4 Inhibitors in Endothelial and Vascular Function in Patients With Type 2 Diabetes Mellitus and Albuminuria

    Not yet reported Attikon Hospital 60 participants Est. completion 2024-12-15 1 site
    Other conditions: Urine Albumin (UAlb), Glycocalyx, Arterial Stiffness
    View official trial listing →
  • Not yet recruiting NCT NCT06644404

    Phase 1 Study of Drug-Drug Interactions Between DWP16001, DWC202407, and DWC202408 in Healthy Adults

    Not yet reported Daewoong Pharmaceutical Co. LTD. 34 participants Est. completion 2025-04-01 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT06654960

    Influence of HRS9531 on Pharmacokinetics of Metformin in Healthy Subjects

    Not yet reported Fujian Shengdi Pharmaceutical Co., Ltd. 20 participants Est. completion 2024-12-26 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06655220

    A Study in Healthy Men to Test Whether BI 1815368 Influences the Amount of Metformin in the Body

    Not yet reported Boehringer Ingelheim 14 participants Est. completion 2025-01-13 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Not yet recruiting NCT NCT06675994

    In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme

    LifeBridge Health 80 participants Est. completion 2025-12-30
    PrediabetesCardiovascular disease Other conditions: Healthy, Hypercholesterolemia, Hypertension, Overweight, Diabetes, Family History of Peripheral Artery Disease, Family History of Cerebrovascular Disease
    View official trial listing →
  • Completed NCT NCT06727838

    Study on Drug Interaction of Metformin Tablets and HRS-7535 Tablets in Healthy Human

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 18 participants Est. completion 2025-01-25 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT06766500

    Pharmacokinetics and Bioequivalence Study of Empagliflozin+Metformin Hydrochloride 5 mg/850 mg Film-coated Tablets (Gedeon Richter Plc., Hungary) Versus Synjardy® 5 mg/850 mg Film-coated Tablets (Boehringer Ingelheim International GmbH, Germany)

    Not yet reported Gedeon Richter Plc. 64 participants Est. completion 2025-02-28 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06793943

    A Study of Interaction of Zasocitinib (TAK-279) With Other Medicines in Healthy Adults

    Not yet reported Takeda 78 participants Est. completion 2025-03-30 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT06871761

    A Trial Comparing HR17031 With Insulin Glargine in Patients With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 393 participants Est. completion 2025-05-13 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06882291

    Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S

    Not yet reported Cairo University 72 participants Est. completion 2025-09-30 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Active, not recruiting NCT NCT06899061

    Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib

    Not yet reported AstraZeneca 41 participants Est. completion 2028-05-19 4 sites
    Other conditions: Advanced Solid Malignancies
    View official trial listing →
  • Not yet recruiting NCT NCT06942390

    Topical Metformin Versus Topical Ketotifen in Melasma Treatment

    Not yet reported Assiut University 60 participants Est. completion 2026-10-30
    Other conditions: Melasma
    View official trial listing →
  • Not yet recruiting NCT NCT06946628

    New Triple Therapy in Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 296 participants Est. completion 2030-12-31 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT06961019

    Clinical Study to Assess the Safety, Efficacy and In-Use Tolerability of Herbal-Based Sugar Support Effervescent Tablets in Type-2 Diabetes Mellitus Patients

    Not yet reported NovoBliss Research Pvt Ltd 14 participants Est. completion 2026-03-14 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07057271

    A Study of CJC-1134-PC Injection in Patients With Type 2 Diabetes With Inadequately Controlled Blood Glucose Level After Metformin Monotherapy or Metformin in Combination With Insulin Secretagogues

    Not yet reported Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd. 464 participants Est. completion 2023-02-21 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07120828

    The Role of CYP8B1 Polymorphisms in Modulating the Biochemical Pathways Affected by SGLT2 Inhibitors in T2DM and Obesity

    Not yet reported Erbil Polytechnic University 260 participants Est. completion 2026-03-15 1 site
    Type 2 diabetes Other conditions: Obese Diabetics, Obese Patients (BMI ≥ 30 kg/m²)
    View official trial listing →
  • Completed NCT NCT07172269

    Mangosteen Supplement as Adjuvant Therapy With Sitagliptin/Metformin in Iraqi Patients With Type 2 Diabetes

    Not yet reported Mais Qais Hbeeb 58 participants Est. completion 2025-05-26 1 site
    Type 2 diabetes Other conditions: Diabete Mellitus, Dyslipidemia in Patients With Diabetes Mellitus, Insulin Resistance
    View official trial listing →
  • Not yet recruiting NCT NCT07215156

    Metformin Versus Chlorhexidine Gel as Adjuncts to Scaling and Root Planing in Stage II Grade B Periodontitis

    Not yet reported Kafrelsheikh University 60 participants Est. completion 2026-06-01 Stand-alone
    Other conditions: Stage II, Grade B Periodontitis, Chronic Periodontitis
    View official trial listing →
  • Not yet recruiting NCT NCT07300007

    PK and Relative Bioavailability of Liquid Metformin vs Tablets in Healthy Adults

    Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-05-28
    Other conditions: Healthy Volunteer
    View official trial listing →
  • Completed NCT NCT07323589

    Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS

    Not yet reported PAEC general hospital 120 participants Est. completion 2025-10-25 1 site
    Other conditions: PCOS (Polycystic Ovary Syndrome)
    View official trial listing →
  • Completed NCT NCT07345507

    Comparison of Efficacy of Metformin Gel 30% vs Triple Combination Cream (Hydroquinone 4%, Flucinolone Acetonide 0.01%, Tretinoin 0.025%) in Treatment of Melasma in Tertiary Care Hospital Karachi

    Not yet reported Jinnah Postgraduate Medical Centre 34 participants Est. completion 2025-08-30 1 site
    Other conditions: Melasma
    View official trial listing →
  • Not yet recruiting NCT NCT07441187

    Efficacy and Safety of Henagliflozin, Retagliptin, and Metformin Extended-Release Tablets in Chinese Patients With Type 2 Diabetes Mellitus

    Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 300 participants Est. completion 2027-12-31
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07451639

    White Mulberry Leaf Extract for Metabolic Health in Overweight Adults Taking Metformin

    Not yet reported Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo 50 participants Est. completion 2024-06-01 1 site
    Other conditions: Weight Management
    View official trial listing →
  • Not yet recruiting NCT NCT07460336

    Effects of Cofrogliptin on Beta-Cell Function in LADA Patients

    Not yet reported Second Xiangya Hospital of Central South University 84 participants Est. completion 2027-12-31 1 site
    Other conditions: Latent Autoimmune Diabetes in Adults (LADA)
    View official trial listing →
  • Completed NCT NCT07541456

    Empagliflozin Versus Non-SGLT2 Oral Drugs for Blood Pressure in Type 2 Diabetes

    Not yet reported Dr. Zarmina Younes 300 participants Est. completion 2025-11-08 1 site
    Type 2 diabetes Other conditions: Hypertension
    View official trial listing →
  • Enrolling by invitation NCT NCT07568574

    Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes

    Not yet reported Enhanced Emirates Limited 60 participants Est. completion 2033-03-01 1 site
    Other conditions: Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes
    View official trial listing →
  • Completed NCT NCT07585396

    Inositol in Letrozol Resistant PCOS Women

    Not yet reported, Not yet reported Kafrelsheikh University 136 participants Est. completion 2026-07-11 1 site
    Other conditions: Polycystic Ovary Syndrome, Infertility
    View official trial listing →
  • Completed NCT NCT07604870

    Krill Oil and Metformin in Women With PCOS and Metabolically Unhealthy Obesity

    Not yet reported Firat University 54 participants Est. completion 2024-04-30 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Obesity, Metabolic
    View official trial listing →
  • Completed NCT NCT07628556

    Antidiabetic Medications and Risk of Cancer

    University of Pecs 74799 participants Est. completion 2025-12-30 1 site
    Other conditions: Cancer
    View official trial listing →
  • Completed NCT NCT07738692

    Effects of Various Types of Ultrasound Therapy in Knee Osteoarthritis

    Not yet reported Horus University 80 participants Est. completion 2026-06-30 1 site
    Osteoarthritis
    View official trial listing →
  • Not yet recruiting NCT NCT07753317

    Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DM

    Not yet reported Cairo University 30 participants Est. completion 2027-03-01
    Other conditions: Controlled Type 2 Diabetic Patients With Periodontitis
    View official trial listing →
  • Not yet recruiting NCT NCT07796477

    A Study of SYH2069 Injection in Participants With T2DM Not Controlled With Diet/Exercise Alone or Metformin

    Not yet reported CSPC Ouyi Pharmaceutical Co., Ltd. 240 participants Est. completion 2027-10-19 1 site
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07806019

    Metformin in Parkinson's Disease: Safety and Efficacy

    Not yet reported Jinnah Medical & Dental College 70 participants Est. completion 2027-02-01
    Other conditions: Parkinsons Disease (PD)
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: Metformin Hydrochloride, ZITUVIMET

Related On The Pen coverage

No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.