GLP-1 Market
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Delayed · As of 9:20 AM
About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Metformin

Company
Ziauddin University
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
53 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

53 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026

Find a Clinical Trial Near Me

See recruiting studies for Metformin and check eligibility with the study team.

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Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

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Trial details
  • Recruiting NCT NCT01638676

    A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients

    Not yet reported, Not yet reported University of Louisville 55 participants Est. completion 2027-06 1 site
    Other conditions: Melanoma
    View official trial listing →
  • Recruiting NCT NCT02647827

    Acupuncture or Metformin for Insulin Resistance in Women With PCOS

    Not yet reported Karolinska Institutet 303 participants Est. completion 2026-06 2 sites
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance, Hyperandrogenism
    View official trial listing →
  • Recruiting NCT NCT02915198

    Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

    Not yet reported VA Office of Research and Development 7410 participants Est. completion 2029-09-28 40 sites
    Other conditions: Prediabetic State, Atherosclerosis, Metformin
    View official trial listing →
  • Recruiting NCT NCT02947503

    Pregnancy Outcomes: Effects of Metformin Study (POEM Study)

    Not yet reported Bethesda Diabetes Research Center 500 participants Est. completion 2043-12 4 sites
    Other conditions: Gestational Diabetes, Insulin Resistance
    View official trial listing →
  • Recruiting NCT NCT02969798

    Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

    Not yet reported The University of Texas Health Science Center at San Antonio 700 participants Est. completion 2027-07 1 site
    Type 2 diabetesPrediabetes
    View official trial listing →
  • Recruiting NCT NCT03424005

    A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

    Not yet reported, Not yet reported Hoffmann-La Roche 1132 participants Est. completion 2030-09-30 53 sites Stand-alone
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT03568630

    Blood Markers of Early Pancreas Cancer

    University of Nebraska 1250 participants Est. completion 2028-07 1 site
    Type 2 diabetesPrediabetes Other conditions: Pancreas Cyst, Chronic Pancreatitis, Genetic Predisposition to Disease, Inherited Disease
    View official trial listing →
  • Recruiting NCT NCT04670666

    Efficacy and Safety of Madalena Association in the Treatment of Type II Diabetes Mellitus

    Not yet reported EMS 270 participants Est. completion 2027-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT04945148

    Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide

    Not yet reported Hopital Foch 640 participants Est. completion 2028-05 7 sites Stand-alone
    Other conditions: Glioblastoma, IDH-wildtype
    View official trial listing →
  • Recruiting NCT NCT05036226

    COAST Therapy in Advanced Solid Tumors and Prostate Cancer

    Not yet reported, Not yet reported Medical University of South Carolina 76 participants Est. completion 2028-05-21 1 site Stand-alone
    Other conditions: Prostate Cancer Recurrent, Solid Tumor, Adult
    View official trial listing →
  • Recruiting NCT NCT05164263

    Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study

    Not yet reported Getz Pharma 2000 participants Est. completion 2027-08-31 6 sites
    Other conditions: Type II Diabetes Mellitus, Efficacy, Self, Safety Issues
    View official trial listing →
  • Recruiting NCT NCT05205317

    Comparison of the Therapeutic Effects of VR and VR + Metformin in the Treatment of Cesarean Section Scar Defect

    Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 100 participants Est. completion 2027-06-30 1 site
    Other conditions: Defect
    View official trial listing →
  • Recruiting NCT NCT05230758

    Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour

    Not yet reported Donald Mabbott 140 participants Est. completion 2027-11-30 20 sites
    Other conditions: Medulloblastoma, Childhood, Cognitive Impairment
    View official trial listing →
  • Recruiting NCT NCT05243654

    Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy

    Not yet reported Oxford University Clinical Research Unit Indonesia 166 participants Est. completion 2026-09-30 6 sites Stand-alone
    Other conditions: Leprosy, Leprosy, Multibacillary, Neglected Tropical Diseases
    View official trial listing →
  • Recruiting NCT NCT05275608

    Effects of VLCKD in Metabolic Syndrome

    Not yet reported Azienda Ospedaliero Universitaria Maggiore della Carita 40 participants Est. completion 2025-12 1 site
    Type 2 diabetesMetabolic syndrome Other conditions: Non-alcoholic Fatty Liver Disease, Obesity
    View official trial listing →
  • Recruiting NCT NCT05316935

    GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients

    Not yet reported, Not yet reported Xiaojun Chen 80 participants Est. completion 2028-03-30 2 sites Stand-alone
    Other conditions: Endometrial Neoplasms, Atypical Endometrial Hyperplasia, Progesterone Resistance
    View official trial listing →
  • Recruiting NCT NCT05414409

    The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

    Not yet reported Heba M. Ismail 114 participants Est. completion 2027-03-01 1 site
    Other conditions: Type 1 Diabetes, Obesity
    View official trial listing →
  • Recruiting NCT NCT05819853

    Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome

    Not yet reported University of Colorado, Denver 80 participants Est. completion 2028-06-30 1 site
    Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Obese
    View official trial listing →
  • Recruiting NCT NCT05900466

    Metformin for Fibromyalgia Symptoms (INFORM Trial)

    Not yet reported University of Utah 72 participants Est. completion 2027-03-31 1 site
    Other conditions: Fibromyalgia Syndrome
    View official trial listing →
  • Recruiting NCT NCT06044025

    A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy

    Not yet reported University of Arkansas 34 participants Est. completion 2028-10 1 site Stand-alone
    Other conditions: Castration Sensitive Prostate Cancer
    View official trial listing →
  • Recruiting NCT NCT06090227

    AMPK-activation by Metformin in FSGS: AMP-FSGS

    Not yet reported, Not yet reported Yale University 30 participants Est. completion 2027-11 2 sites Stand-alone
    Other conditions: Focal Segmental Glomerulosclerosis
    View official trial listing →
  • Recruiting NCT NCT06096259

    Preventing Injured Knees From osteoArthritis: Severity Outcomes

    Not yet reported Brigham and Women's Hospital 512 participants Est. completion 2029-12 9 sites
    Osteoarthritis Other conditions: ACL Tear
    View official trial listing →
  • Recruiting NCT NCT06120881

    Precision Dosing of Metformin in Youth With T2D

    Not yet reported University of California, San Francisco 20 participants Est. completion 2026-12-31 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06185179

    Metformin and Muscle Recovery

    Not yet reported University of Utah 50 participants Est. completion 2030-05-31 1 site
    Other conditions: Muscle Atrophy or Weakness
    View official trial listing →
  • Recruiting NCT NCT06445946

    DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

    Not yet reported Ohio State University 1572 participants Est. completion 2030-12 24 sites Stand-alone
    Other conditions: Gestational Diabetes Mellitus, Pregnancy, High Risk
    View official trial listing →
  • Recruiting NCT NCT06459310

    Pilot Study on Evaluating the Geroprotective Effect of Metformin

    Not yet reported Xuanwu Hospital, Beijing 130 participants Est. completion 2028-07-31 1 site Stand-alone
    Other conditions: Metformin, Aging
    View official trial listing →
  • Recruiting NCT NCT06613854

    Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in Individuals With Type 2 Diabetes

    Not yet reported University Medical Centre Ljubljana 90 participants Est. completion 2027-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06627322

    A Registry-based Randomized Controlled Trial in Type 2 Diabetes With Cardiovascular Risk Factors (REMATCH)

    Not yet reported Kyu Chang Won 5950 participants Est. completion 2029-09-30 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06707012

    Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese Patients

    Not yet reported Fazaia Ruth Pfau Medical College 140 participants Est. completion 2026-12 2 sites Stand-alone
    Other conditions: Depression
    View official trial listing →
  • Recruiting NCT NCT06763328

    Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy

    Not yet reported City of Hope Medical Center 80 participants Est. completion 2029-06-16 3 sites
    Other conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Invasive Breast Carcinoma
    View official trial listing →
  • Recruiting NCT NCT06806345

    Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause

    Not yet reported, Not yet reported Cairo University 40 participants Est. completion 2025-04-28 1 site Stand-alone
    Other conditions: Insulin Resistance Syndrome
    View official trial listing →
  • Recruiting NCT NCT06875193

    DM Treatment to Evaluate the Efficacy and Safety of Dapagliflozin or Pioglitazone in Patients with Type 2 Diabetes

    Not yet reported Dong Wha Pharmaceutical Co. Ltd. 196 participants Est. completion 2025-12-31 1 site
    Other conditions: Type2diabetes
    View official trial listing →
  • Recruiting NCT NCT06924658

    Metformin in Safety and Efficacy in Gouty Patients

    Not yet reported Mostafa Bahaa 70 participants Est. completion 2026-11-20 1 site
    Other conditions: Gout
    View official trial listing →
  • Recruiting NCT NCT06948825

    Effectiveness Study of a Lifestyle Intervention Versus Metformin in Mothers With Recent Gestational Diabetes

    Not yet reported George Washington University 60 participants Est. completion 2026-11 1 site
    Other conditions: Weight Loss, Gestational Diabetes Mellitus in Pregnancy, Postpartum Care
    View official trial listing →
  • Recruiting NCT NCT07074379

    Endotherapy and/or Extracorporeal Shockwave Lithotripsy for Painless Chronic Pancreatitis

    Not yet reported Changhai Hospital 126 participants Est. completion 2027-08-01 1 site
    Other conditions: Painless Chronic Pancreatitis
    View official trial listing →
  • Recruiting NCT NCT07093476

    Efficacy and Safety of Add-On Therapy With Empagliflozin in Patients With Type 2 Diabetes on a Background of Alogliptin and Metformin

    Not yet reported Celltrion 171 participants Est. completion 2027-04 1 site
    Type 2 diabetes Other conditions: Diabete Type 2, DM
    View official trial listing →
  • Recruiting NCT NCT07129473

    Hyperemesis Gravidarum Risk Reduction With Metformin

    Not yet reported, Not yet reported University of Southern California 224 participants Est. completion 2031-03 2 sites Stand-alone
    Other conditions: Hyperemesis Gravidarum
    View official trial listing →
  • Recruiting NCT NCT07131384

    Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes

    Not yet reported University of Virginia 24 participants Est. completion 2027-06-30 1 site
    Prediabetes Other conditions: Males, Females, Sedentary, Metformin
    View official trial listing →
  • Recruiting NCT NCT07254572

    Anti-atherosclerotic Efficacy of Selected Antidiabetic Drugs in Patients With Coronary Artery Disease and Pre-diabetes

    Not yet reported National Institute of Cardiology, Warsaw, Poland 300 participants Est. completion 2029-08-01 1 site
    Cardiovascular diseasePrediabetes
    View official trial listing →
  • Recruiting NCT NCT07289399

    Is There a Benefit From Addition of Treadmill Walking to Diet Restriction in Psoriasis Women With PCOS?

    Not yet reported Cairo University 40 participants Est. completion 2026-05-15 1 site
    Other conditions: Psoriasis, Polycystic Ovary Syndrome
    View official trial listing →
  • Recruiting NCT NCT07291297

    Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

    Not yet reported Wake Forest University Health Sciences 50 participants Est. completion 2033-10 2 sites
    Other conditions: Sarcoma Metastatic, Sarcoma, Soft Tissue
    View official trial listing →
  • Recruiting NCT NCT07293325

    Semaglutide and Tirzepatide for Genetic Aging Delay in Adults With Obesity

    Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 66 participants Est. completion 2027-06-02 1 site
    Other conditions: Adults With Simple Obesity
    View official trial listing →
  • Recruiting NCT NCT07297290

    Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)

    Not yet reported University Of Nigeria Teaching Hospital 220 participants Est. completion 2027-09-30 2 sites Stand-alone
    Other conditions: Obesity and Cardiovascular Risk, Insulin Resistance, Obesity (Body Mass Index >30 kg/m2)
    View official trial listing →
  • Recruiting NCT NCT07366944

    PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes

    Not yet reported Cairo University 40 participants Est. completion 2026-06-05 1 site
    Other conditions: Polycystic Ovary Syndrome, Dry Eye, Obesity
    View official trial listing →
  • Recruiting NCT NCT07372625

    A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

    Not yet reported PMV Pharmaceuticals, Inc 14 participants Est. completion 2028-01 5 sites Stand-alone
    Other conditions: TP53 Y220C Mutation, Advanced Solid Tumors
    View official trial listing →
  • Recruiting NCT NCT07379333

    A Study to Evaluate Efficacy and Safety of HM11260C in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin

    Not yet reported Hanmi Pharmaceutical Company Limited 118 participants Est. completion 2028-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07442006

    Glycemic Variability of Combination Therapies in T2DM

    Not yet reported JW Pharmaceutical 178 participants Est. completion 2027-03-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07446400

    A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together

    Not yet reported Otsuka Pharmaceutical Development & Commercialization, Inc. 48 participants Est. completion 2026-11-07 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Recruiting NCT NCT07550816

    Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants

    Not yet reported Beijing QL Biopharmaceutical Co.,Ltd 60 participants Est. completion 2027-03-26 1 site Stand-alone
    Other conditions: Overweight,Obesity
    View official trial listing →
  • Recruiting NCT NCT07591246

    Efficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid Hypofunction

    Not yet reported Cairo University 40 participants Est. completion 2026-12-30 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Non-Alcoholic Fatty Pancreatic Disease, Subclinical hypothyroïdism
    View official trial listing →
  • Recruiting NCT NCT07630779

    Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients

    Not yet reported Beni-Suef University 180 participants Est. completion 2026-12 1 site
    Other conditions: Poly Cystic Ovary Syndrome
    View official trial listing →
  • Recruiting NCT NCT07693452

    Metformin in Pseudomyxoma Peritonei Secondary to Appendiceal Mucinous Neoplasms

    Not yet reported University of California, Irvine 15 participants Est. completion 2029-07 1 site
    Other conditions: Appendiceal Mucinous Neoplasm, Pseudomyxoma Peritonei
    View official trial listing →
  • Recruiting NCT NCT07724132

    An Evaluation of Treatments for Sustained Clinical Response (18 Months) in Symptomatic Alzheimer's Disease

    Not yet reported University College, London 1200 participants Est. completion 2031-03 2 sites
    Other conditions: Alzheimer's Disease (AD), Mild Cognitive Impairment Due to Alzheimer's Disease, Alzheimer Disease Dementia
    View official trial listing →
  • Completed NCT NCT00005104

    Randomized Study of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Women With Polycystic Ovary Syndrome

    Not yet reported National Center for Research Resources (NCRR) 99 participants 6 sites
    Other conditions: Polycystic Ovary Syndrome, Hyperinsulinism
    View official trial listing →
  • Completed NCT NCT00018616

    Improving Compliance With Metformin

    Not yet reported US Department of Veterans Affairs 79 participants Est. completion 2005-01 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00032487

    Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)

    Not yet reported VA Office of Research and Development 1791 participants Est. completion 2008-05-30 21 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00035542

    A Research Study to Determine the Safety and Efficacy of Glucovance Compared to Metformin and Glyburide in Children and Adolescents With Type 2 Diabetes.

    Not yet reported Bristol-Myers Squibb Est. completion 2003-10 50 sites
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00035568

    A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes

    Not yet reported Bristol-Myers Squibb Est. completion 2003-06 9 sites
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00067951

    A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics

    Not yet reported GlaxoSmithKline 190 participants Est. completion 2004-11-30 94 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00081328

    Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 699 participants Est. completion 2014-02 16 sites Stand-alone
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Completed NCT NCT00097500

    Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 69 participants Est. completion 2009-12 3 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00097877

    Comparison of Biphasic Insulin Aspart 70/30 Versus Insulin Glargine in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 293 participants Est. completion 2006-11 73 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00099892

    Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 544 participants Est. completion 2005-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00106704

    Sulfonylurea Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-035)

    Not yet reported Merck Sharp & Dohme LLC 441 participants Est. completion 2007-01
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00111631

    A Study of DPP-IV Inhibitor in Patients With Type 2 Diabetes

    Not yet reported Hoffmann-La Roche 218 participants Est. completion 2006-10 37 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00118963

    Effect of Repaglinide Versus Metformin Treatment in Non-Obese Patients With Type-2-Diabetes

    Not yet reported Steno Diabetes Center Copenhagen 102 participants Est. completion 2006-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00121667

    Study Assessing Saxagliptin Treatment In Type 2 Diabetic Subjects Who Are Not Controlled With Metformin Alone

    Not yet reported AstraZeneca 1462 participants Est. completion 2010-02 152 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00121966

    South Danish Diabetes Study: Evaluation of the Antidiabetic Treatment of Type 2 Diabetes Mellitus

    Not yet reported Odense University Hospital 400 participants Est. completion 2007-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00134303

    Trial Comparing Metformin Versus Placebo in Non Alcoholic Steatohepatitis (NASH) Patients Receiving Bariatric Surgery for Obesity

    Not yet reported University Hospital, Ghent 65 participants Est. completion 2006-03-31 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT00135330

    An Evaluation of Exenatide and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 137 participants Est. completion 2008-07 19 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00151411

    Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS)

    Not yet reported Milton S. Hershey Medical Center 114 participants Est. completion 2008-03 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00156897

    Efficacy and Safety of ATL-962 in Obese Diabetics

    Not yet reported Alizyme 600 participants Est. completion 2005-10 37 sites
    Other conditions: Non-Insulin-Dependent Diabetes Mellitus, Obesity
    View official trial listing →
  • Terminated NCT NCT00159211

    Abdominal Adipose Tissue Distribution in Type 2 Diabetic Patients Treated During 6 Months With Pioglitazone or Insulin

    Not yet reported Assistance Publique - Hôpitaux de Paris 28 participants Est. completion 2007-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00159575

    Metformin in Assisted Reproduction-MET-AR-study

    Not yet reported Norwegian University of Science and Technology 150 participants Est. completion 2010-04 2 sites
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00184626

    Comparison of Insulin Glargine Versus Biphasic Insulin Aspart 30/70 or Biphasic Insulin Aspart 30/70 in Combination With Metformin in Subjects With Type 2 Diabetes.

    Not yet reported Novo Nordisk A/S 97 participants Est. completion 2005-10-24 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT00203632

    Glitazones and Endothelial Function (GATE)

    Not yet reported University of Calgary 40 participants Est. completion 2007-10 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00263276

    A Trial of BMS-512148 in Patients With Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 389 participants Est. completion 2007-02 144 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00265746

    Prevention of Diabetes Mellitus Development in Women Who Had Already Experienced A Gestational Diabetes

    Not yet reported Medical University of Lodz
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00269061

    Study In Patients With Type 2 Diabetes Who Are Taking Metformin And Sulfonylurea, Metformin And Insulin, Or Insulin

    Not yet reported GlaxoSmithKline 32 participants 1 site
    Other conditions: Non-Insulin-Dependent Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00272064

    ELEONOR STUDY: Insulin Glulisine in Type 2 Diabetes Mellitus.

    Not yet reported Sanofi 352 participants Est. completion 2008-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00279045

    Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide

    Not yet reported GlaxoSmithKline 4426 participants Est. completion 2006-06-19 490 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00283049

    Insulin Glargine Injection Treatment in Place of Thiazolidinedione (TZD), Sulfonylurea, or Metformin in Triple Agent Therapy for Type 2 Diabetes Mellitus (T2DM) Adult Subjects With Unsatisfactory Control

    Not yet reported Sanofi 390 participants Est. completion 2008-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00286442

    Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus

    Not yet reported Takeda 527 participants Est. completion 2007-06 56 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00290940

    Evaluation of Glucose Lowering Effect, Safety and Tolerability of CS-917

    Not yet reported Daiichi Sankyo 400 participants Est. completion 2007-04 66 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00308373

    Effects of Fats on Blood Glucose in People With and Without Type 2 Diabetes Mellitus

    Not yet reported Mayo Clinic 73 participants Est. completion 2005-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00317928

    Efficacy of Metformin in PCOS: Metabolic and Hormonal Factors

    Not yet reported Aarhus University Hospital Skejby 50 participants Est. completion 2004-09
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT00319293

    Efficacy of Metformin in Lean Women With Polycystic Ovary Syndrome

    Not yet reported Aarhus University Hospital Skejby 20 participants
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00324363

    Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Metformin or Sulfonylureas and Metformin

    Not yet reported AstraZeneca 466 participants Est. completion 2007-04 14 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00327015

    A Phase 3 Study of BMS-477118 in Combination With Metformin in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

    Not yet reported AstraZeneca 1306 participants Est. completion 2008-12 211 sites
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00328172

    Efficacy and Safety of 3 Doses of BI1356 (Linagliptin) in Type 2 Diabetes Patients

    Not yet reported Boehringer Ingelheim 302 participants 71 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00332085

    Pilot Trial of Chromium-Metformin Combination in Type 2 Diabetes

    Not yet reported Bastyr University 40 participants Est. completion 2007-03 2 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00348712

    Efficacy and Safety of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 301 participants Est. completion 2008-03-05 74 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00350779

    Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)

    Not yet reported Merck Sharp & Dohme LLC 262 participants Est. completion 2008-06-11
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00361868

    Fenofibrate and Metformin Fixed Combination vs Rosiglitazone - FAME ROSI

    Not yet reported Solvay Pharmaceuticals 88 participants Est. completion 2007-12 70 sites Stand-alone
    Other conditions: Dyslipidemia, Glucose Metabolism Disorder
    View official trial listing →
  • Completed NCT NCT00374907

    A Study Assessing Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

    Not yet reported AstraZeneca 156 participants Est. completion 2009-12 3 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00382096

    Efficacy of Fixed Combination Therapy of Vildagliptin and Metformin Compared to the Individual Monotherapy Components in Drug Naive Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 1179 participants Est. completion 2008-06-03 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00390273

    Effect of Metformin on Lactate Metabolism

    Not yet reported, Not yet reported Centre de Recherche en Nutrition Humaine Rhone-Alpe 20 participants Est. completion 2007-10 1 site
    Other conditions: Hyperlactatemia
    View official trial listing →
  • Completed NCT NCT00400231

    The Fenofibrate and Metformin for Atherogenic Dyslipidemia (FAMA) Study

    Not yet reported University of Pennsylvania 124 participants Est. completion 2008-03 1 site
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT00402909

    Safety and Efficacy of Nateglinide in Patients With Type 2 Diabetes Already Taking Insulin Glargine, Metformin and/or Pioglitazone or Rosiglitazone

    Not yet reported Novartis Pharmaceuticals 28 participants Est. completion 2007-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00420511

    Beta-Cell Function and Sitagliptin Trial (BEST)

    Not yet reported Samuel Lunenfeld Research Institute, Mount Sinai Hospital 21 participants Est. completion 2009-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00423501

    A Study of a GLP-1 Analogue in Patients With Type 2 Diabetes Treated With Metformin.

    Not yet reported Hoffmann-La Roche 306 participants Est. completion 2007-11 49 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00432276

    Efficacy of Alogliptin and Pioglitazone in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Takeda 803 participants Est. completion 2009-06 86 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT00441363

    Efficacy and Safety of Cycloset® Compared With Placebo When Added to Metformin

    Not yet reported VeroScience 66 participants Est. completion 2006-03
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00449605

    A Glycemic Control Evaluation of Glimepiride Versus Rimonabant on Top of Metformin in Type 2 Diabetes

    Not yet reported Sanofi 508 participants Est. completion 2009-03 15 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00449930

    Sitagliptin Comparative Study in Patients With Type 2 Diabetes (0431-049)

    Not yet reported Merck Sharp & Dohme LLC 1050 participants Est. completion 2008-07-25
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00454233

    A Safety and Efficacy Study With YM543 in Type 2 Diabetes Mellitus Subjects

    Not yet reported Astellas Pharma Inc 97 participants Est. completion 2008-06 6 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00463502

    The Effect of Metformin Treatment on Thyroid Hormone Metabolism in Euthyroid Patients With Type 2 Diabetes Mellitus

    Not yet reported Haydarpasa Numune State Hospital
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00469586

    Efficacy and Safety of Inhaled Insulin Compared to Metformin and Glimepiride in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 174 participants Est. completion 2008-04-24 59 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00473876

    Metformin in Insulin Resistant Left Ventricular (LV) Dysfunction (TAYSIDE Trial)

    Not yet reported University of Dundee 62 participants Est. completion 2009-04 1 site
    Heart failure Other conditions: Insulin Resistance
    View official trial listing →
  • Terminated NCT NCT00479466

    Dose-Range Finding Study for MK0893 (0893-008)

    Not yet reported Merck Sharp & Dohme LLC 342 participants Est. completion 2008-05
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00481429

    Predictive Markers of Glitazone Efficacy in Diabetic Patients - Pilot Study

    Imperial College London Est. completion 2008-01 4 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00486187

    Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study

    Not yet reported Dr. Milan Gupta 103 participants Est. completion 2009-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00490178

    Acceptability Study of a New Fixed Combination of Fenofibrate 80 mg BID and Metformin 1000 mg BID in Type 2 Diabetes and Dyslipidemia

    Not yet reported Solvay Pharmaceuticals 29 participants 3 sites
    Type 2 diabetes Other conditions: Dyslipidemia
    View official trial listing →
  • Terminated NCT NCT00494663

    A Phase 2b Study of DIO-902 or DIO-902 Placebo in Addition to Metformin and Atorvastatin or Atorvastatin Placebo for Type 2 Diabetes

    Not yet reported DiObex 200 participants Est. completion 2008-12 24 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00494884

    Vildagliptin 100 mg Once Daily vs. Placebo as add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

    Not yet reported Novartis Est. completion 2008-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00510588

    Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease

    Not yet reported University of Leipzig 120 participants Est. completion 2013-10 1 site
    Cardiovascular diseasePrediabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT00513630

    Study on the Prognosis and Effect of Anti-diabetic Drugs on Type-2 Diabetes Mellitus With Coronary Artery Disease

    Not yet reported Shanghai Jiao Tong University School of Medicine 304 participants Est. completion 2010-07 1 site
    Type 2 diabetesCardiovascular disease
    View official trial listing →
  • Completed NCT NCT00528879

    A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone

    Not yet reported AstraZeneca 915 participants Est. completion 2010-05 75 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00538486

    A Randomized, Double-Blind, Active Control Trial Comparing Effects of Telmisartan, Candesartan and Amlodipine, Alone or Plus Metformin, on Non-Diabetic, Obese Hypertensive Patients

    Not yet reported Third Military Medical University 360 participants Est. completion 2009-06 1 site Stand-alone
    Other conditions: Hypertension, Obesity
    View official trial listing →
  • Withdrawn NCT NCT00541567

    BMS-646256 in Obese and Overweight Type 2 Diabetics

    Not yet reported, Not yet reported Solvay Pharmaceuticals 600 participants Est. completion 2010-06
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00541775

    Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)

    Not yet reported Merck Sharp & Dohme LLC 273 participants Est. completion 2007-03 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00543738

    MK0767 and Metformin Combination Study (0767-028)

    Not yet reported Merck Sharp & Dohme LLC 114 participants Est. completion 2003-12
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT00544518

    Impact of Benfluorex Versus Metformin on Glucose Control and Insulin Secretion in Chinese Type 2 Diabetic Patients

    Not yet reported Air Force Military Medical University, China 240 participants Est. completion 2008-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00545584

    Addition Of Januvia (Sitagliptin) Improves Glycemic Control In Patients Inadequately Controlled By Metformin (MK0431-078)

    Not yet reported Merck Sharp & Dohme LLC 1512 participants Est. completion 2009-11-19
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00546442

    Treatment Insulin Resistence in HCV G-1 Patient

    Not yet reported Valme University Hospital 126 participants Est. completion 2007-01 19 sites
    Other conditions: Chronic Hepatitis C
    View official trial listing →
  • Completed NCT NCT00546728

    The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes

    Not yet reported St. Paul Heart Clinic 50 participants Est. completion 2011-07 2 sites
    Prediabetes
    View official trial listing →
  • Completed NCT NCT00575588

    52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period

    Not yet reported AstraZeneca 891 participants Est. completion 2010-08 94 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00592969

    Efficacy and Safety of Metformin Plus Biphasic Insulin Aspart 30 in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 164 participants Est. completion 2004-11-02 2 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00598793

    Biphasic Insulin Aspart 30 in Type 2 Diabetes Failing OAD Therapy

    Not yet reported Novo Nordisk A/S 242 participants Est. completion 2004-03 27 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00601250

    Efficacy and Safety of B I1356 (Linagliptin) vs. Placebo Added to Metformin Background Therapy in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 701 participants 82 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00603239

    Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using a Thiazolidinedione or a Thiazolidinedione and Metformin

    Not yet reported AstraZeneca 165 participants Est. completion 2009-07 25 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00605475

    Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACZ885 in Patients With Type 2 Diabetes

    Not yet reported Novartis 231 participants Est. completion 2010-09 13 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00613951

    Comparison of Two NN5401 Formulations Versus Biphasic Insulin Aspart 30, All in Combination With Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 182 participants Est. completion 2008-08 31 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00627445

    Effect of Biphasic Insulin Aspart 50 on Blood Glucose Control in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 441 participants Est. completion 2009-01 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00636766

    Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque

    Not yet reported Aristotle University Of Thessaloniki 300 participants Est. completion 2009-01 1 site Stand-alone
    Cardiovascular diseaseType 2 diabetesMetabolic syndrome Other conditions: Carotid Atherosclerosis
    View official trial listing →
  • Completed NCT NCT00637273

    A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)

    Not yet reported AstraZeneca 514 participants Est. completion 2009-07 62 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00638716

    A Study to Evaluate the Efficacy and Safety of CJC-1134-PC in Patients With Type 2 Diabetes Mellitus Who Are Currently on Metformin Monotherapy

    Not yet reported ConjuChem 122 participants Est. completion 2008-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00643851

    An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release Tablets

    Not yet reported AstraZeneca 994 participants Est. completion 2009-08 99 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00648492

    Food Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR 500 mg

    Not yet reported Mylan Pharmaceuticals Inc 18 participants Est. completion 2002-11 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00649350

    Food Study Metformin Hydrochloride ER Tablets 750 mg and Glucophage XR 750 mg

    Not yet reported Mylan Pharmaceuticals Inc 28 participants Est. completion 2003-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00657943

    The Copenhagen Insulin and Metformin Therapy Trial

    Not yet reported Steno Diabetes Center Copenhagen 415 participants Est. completion 2012-12 9 sites
    Type 2 diabetes Other conditions: Atherosclerosis, Arteriosclerosis
    View official trial listing →
  • Completed NCT NCT00660907

    Efficacy and Safety of Dapagliflozin in Combination With Metformin in Type 2 Diabetes Patients

    Not yet reported AstraZeneca 1217 participants Est. completion 2013-01 76 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00661362

    Evaluate Efficacy and Safety of Saxagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes

    Not yet reported AstraZeneca 570 participants Est. completion 2009-09 30 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00669864

    Effect of Biphasic Insulin Aspart 30 Combined With Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin

    Not yet reported Novo Nordisk A/S 293 participants Est. completion 2009-04 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00676338

    Safety and Efficacy of Exenatide Once Weekly Injection Versus Metformin, Dipeptidyl Peptidase-4 Inhibitor, or Thiazolidinedione as Monotherapy in Drug-Naive Patients With Type 2 Diabetes (DURATION-4)

    Not yet reported AstraZeneca 820 participants Est. completion 2011-01 106 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00678080

    Metformin Versus Insulin in Pregnant Women With Type 2 Diabetes

    Not yet reported The University of Texas Health Science Center, Houston 25 participants Est. completion 2011-08 3 sites Stand-alone
    Other conditions: Pregnancy Complications
    View official trial listing →
  • Completed NCT NCT00682448

    Metformin for the Prevention of the Metabolic Side-effects of Zyprexa

    Not yet reported Rush University Medical Center 25 participants Est. completion 2011-08 1 site
    Other conditions: Metabolic Complications
    View official trial listing →
  • Completed NCT NCT00686634

    Sitagliptin in Combination With Metformin and Sulfonylurea

    Not yet reported Charles Drew University of Medicine and Science 108 participants Est. completion 2010-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00690456

    Effect of Rimonabant and Metformin Combination on Glycemic Control in Patients With Type 2 Diabetes

    Not yet reported Sanofi 403 participants Est. completion 2009-02 13 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00694057

    Safety, Tolerance and Activity of HE3286 in Patients With Type 2 Diabetes Mellitus

    Not yet reported Harbor Therapeutics 164 participants Est. completion 2010-01 22 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00694759

    Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)

    Not yet reported Oregon Health and Science University 37 participants Est. completion 2011-07 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT00699036

    Rosiglitazone Versus Rosiglitazone and Metformin Versus Rosiglitazone and Avandia in the Treatment of Nonalcoholic Steatohepatitis (NASH)

    Not yet reported Brooke Army Medical Center 165 participants Est. completion 2009-08 1 site
    MASHMASLD
    View official trial listing →
  • Completed NCT NCT00700817

    The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Novo Nordisk A/S 665 participants Est. completion 2010-06 166 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00703755

    A Randomized, Double-Blind Trial Comparing the Efficacy and Safety of Fenofibrate, Metformin, Their Combination and Placebo in Patients With Metabolic Syndrome.

    Not yet reported Solvay Pharmaceuticals 2288 participants Est. completion 2004-06 101 sites
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT00714233

    Treatment of Adolescent Polycystic Ovary Syndrome (PCOS)

    Not yet reported University of Rochester 43 participants Est. completion 2007-12 Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00722371

    MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2)

    Not yet reported Merck Sharp & Dohme LLC 1615 participants Est. completion 2011-03-25 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00723307

    Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study

    Not yet reported Professor Naveed Sattar 173 participants Est. completion 2012-12 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00727857

    Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.

    Not yet reported Takeda 600 participants Est. completion 2008-08 77 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00740051

    A Randomised, db, Placebo-controlled Study of BI 1356 for 18 Weeks Followed by a 34 Week Double-blind Extension Period (Placebo Patients Switched to Glimepiride) in Type 2 Diabetic Patients for Whom Treatment With Metformin is Inappropriate

    Not yet reported Boehringer Ingelheim 227 participants 53 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00744367

    A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Plus Pioglitazone.

    Not yet reported Hoffmann-La Roche 326 participants Est. completion 2010-11 113 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00749190

    BI 10773 add-on to Metformin in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 495 participants 116 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00751114

    Evaluation of Insulin Glargine Versus Sitagliptin in Insulin-naive Patients

    Not yet reported Sanofi 515 participants Est. completion 2011-07 17 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00762957

    Safety and Efficacy of TAK-559 in Combination With Metformin in Patients With Type 2 Diabetes Mellitus.

    Not yet reported Takeda 15 participants Est. completion 2004-12 Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00763815

    GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Pioglitazone

    Not yet reported Sanofi 484 participants Est. completion 2011-06 150 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00767351

    Variation in Serum Levels of Metformin in Patients With Reduced Renal Function

    Skane University Hospital 30 participants Est. completion 2009-07
    Type 2 diabetes Other conditions: Metformin, Pharmacokinetics
    View official trial listing →
  • Completed NCT NCT00770445

    Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus.

    Not yet reported Takeda 121 participants Est. completion 2010-07 18 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00770835

    Efficacy and Safety of Pioglitazone in Treating Subjects With Vascular Complications Associated With Type 2 Diabetes Mellitus.

    Not yet reported Takeda 39 participants Est. completion 2011-05 2 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00772174

    Efficacy and Safety Study of Pioglitazone Combined With Metformin on Metabolic Syndrome in Subjects With Type 2 Diabetes

    Not yet reported Takeda 418 participants Est. completion 2008-02 Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00778141

    Bioequivalence Study of Metformin HCl 750 mg XR Tablets Under Non Fasting Conditions

    Not yet reported Ranbaxy Laboratories Limited 36 participants Est. completion 2004-06 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00783744

    Insulin Glargine Combination Therapies in Type II Diabetics

    Not yet reported Sanofi 375 participants 10 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00789035

    12 Weeks Treatment With 3 Different Doses of BI 10773 in Type 2 Diabetic Patients

    Not yet reported Boehringer Ingelheim 408 participants 74 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00790348

    Effect of Januvia on Ghrelin and Other Gut Hormones in Patients With Diabetes

    Wayne State University 45 participants 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00794963

    Aggressive Treatment of Metabolic Syndrome in Patients Receiving Clozapine for Schizophrenia

    Not yet reported Northwell Health 8 participants Est. completion 2010-05 1 site Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT00806234

    Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics

    Not yet reported Johns Hopkins University 127 participants Est. completion 2014-03 4 sites
    Other conditions: Psychotic Disorders
    View official trial listing →
  • Completed NCT NCT00819884

    To Evaluate 24-hr Glucose After OD vs BD AZD1656

    Not yet reported AstraZeneca 36 participants Est. completion 2009-05 1 site
    Other conditions: Type II Diabetes
    View official trial listing →
  • Completed NCT NCT00822211

    Efficacy of add-on Therapy With Vildagliptin in Chinese Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy

    Not yet reported Novartis 404 participants Est. completion 2009-12 17 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00823992

    A Study of Taspoglutide Versus Placebo for the Treatment of Obese Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Monotherapy

    Not yet reported Hoffmann-La Roche 305 participants Est. completion 2010-05 71 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00830076

    A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)

    Not yet reported Merck Sharp & Dohme LLC 18 participants Est. completion 2009-05-14
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00833027

    ALPHA Sitagliptin Add on to Metformin (0431-103)

    Not yet reported Merck Sharp & Dohme LLC 608 participants Est. completion 2009-10-30
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00834743

    Metformin ER 750 mg Tablets, Fasting

    Not yet reported Teva Pharmaceuticals USA 32 participants Est. completion 2003-08 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00835497

    5 mg Glipizide/500 mg Metformin Hydrochloride Tablets, Fasting

    Not yet reported Teva Pharmaceuticals USA 40 participants Est. completion 2004-06 2 sites
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00835861

    Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes

    Not yet reported University of North Carolina, Chapel Hill 31 participants Est. completion 2010-04 1 site Stand-alone
    Other conditions: Non Insulin Dependent Diabetes, Pregnancy
    View official trial listing →
  • Completed NCT NCT00836472

    Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fasting

    Not yet reported Teva Pharmaceuticals USA 60 participants Est. completion 2003-04 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00838903

    Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes

    Not yet reported GlaxoSmithKline 1049 participants Est. completion 2013-04 386 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00839527

    A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes

    Not yet reported GlaxoSmithKline 685 participants Est. completion 2013-04 358 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00849056

    Safety and Efficacy of Albiglutide in Type 2 Diabetes

    Not yet reported GlaxoSmithKline 310 participants Est. completion 2013-01 331 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00856986

    The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 987 participants Est. completion 2010-11 233 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00859898

    Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 Diabetes

    Not yet reported AstraZeneca 1093 participants Est. completion 2010-05 123 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00865241

    A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 36 participants Est. completion 2002-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865748

    A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 40 participants Est. completion 2004-01 1 site
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT00881725

    A Study of Pre-operative Metformin in Prostate Cancer

    Not yet reported University Health Network, Toronto 24 participants Est. completion 2012-06 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT00883259

    Metformin and Gestational Diabetes in High-risk Patients: a RCTs

    Not yet reported University Magna Graecia 80 participants 3 sites Stand-alone
    Other conditions: Obesity, Polycystic Ovary Syndrome, Gestational Diabetes
    View official trial listing →
  • Terminated NCT NCT00883766

    Polycystic Ovary Syndrome (PCOS) and In Vitro Fertilization (IVF): A Comparison Between Standard Long Protocol Versus an Antagonist Protocol Starting on Day 1

    Not yet reported Fundacion Dexeus 172 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, In Vitro Fertilization
    View official trial listing →
  • Completed NCT NCT00897884

    Clinical and Biologic Effects of Metformin in Early Stage Breast Cancer

    Not yet reported Mount Sinai Hospital, Canada 39 participants Est. completion 2011-07 2 sites
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00911313

    Letrozole or Combined Metformin Clomiphene Citrate (CC) for Women With CC Resistant Polycystic Ovary Syndrome

    Not yet reported Mansoura University 250 participants Est. completion 2009-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00924573

    Comparative Study of HOE490 O (Glimepiride and Metformin) Compared With Placebo on Top of Glimepiride

    Not yet reported Sanofi 189 participants Est. completion 2010-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00929539

    Safety and Efficacy Study of JTT-130 in Obese Type 2 Diabetic Patients

    Not yet reported Akros Pharma Inc. 496 participants Est. completion 2010-07 62 sites
    Other conditions: Type II Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT00935805

    Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy

    Hospital de Clinicas de Porto Alegre 124 participants Est. completion 2012-07 1 site
    Other conditions: Diabetes Mellitus, Arterial Hypertension
    View official trial listing →
  • Completed NCT NCT00940472

    Study on DMMET-01 Versus Metformin on Improvement of Metabolic Control in Naive Type 2 Diabetes Patients

    Not yet reported, Not yet reported Laboratorios Silanes S.A. de C.V. 20 participants 1 site
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT00941148

    Beta-Cell Function of Insulin Glargine Compared to Neutral Protamine Hagedorn (NPH) Insuline and to Insulin Detemir in Combination With Metformin

    Not yet reported ikfe-CRO GmbH 30 participants Est. completion 2009-03 1 site
    Other conditions: Type 2 Diabetic Patients, Insufficient Metabolic Control, OAD Treatment
    View official trial listing →
  • Completed NCT NCT00941239

    Tolerability and Pharmacokinetics of Metformin and Metformin Extended Release (ER)

    Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2007-02 1 site
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT00941382

    Sibutramine-metformin Combination Versus Sibutramine and Metformin Monotherapy in Obese Patients

    Not yet reported Laboratorios Silanes S.A. de C.V. 60 participants Est. completion 2009-09 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT00942123

    Study On the Role of Mitochondrial Dysfunction in the Pathogenesis of Metformin-associated Lactic Acidosis

    Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 10 participants Est. completion 2011-10 1 site
    Other conditions: Lactic Acidosis, Metformin
    View official trial listing →
  • Completed NCT NCT00942188

    A Study of LY2189102 in Patients With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 106 participants Est. completion 2010-11 18 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00960661

    A Trial Comparing Two Therapies: Basal Insulin/Glargine, Exenatide and Metformin Therapy (BET) or Basal Insulin/Glargine, Bolus Insulin Lispro and Metformin Therapy (BBT) in Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 1036 participants Est. completion 2012-08 95 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00965991

    Metformin Compared to Glyburide in Gestational Diabetes

    Not yet reported University of New Mexico 149 participants Est. completion 2023-08 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT00969566

    Predictive Parameters for Efficacy of Sitagliptin and Metformin Combination

    Not yet reported Seoul National University Bundang Hospital 150 participants Est. completion 2011-07 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00970593

    Study Evaluating Safety, Tolerability, And Action Of OAP-189 In Subjects With Type 2 Diabetes On Metformin

    Not yet reported Pfizer 92 participants Est. completion 2011-07-25 2 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00978263

    Comparison of Glargine and Oral Antidiabetic Drugs (OADs) in Newly Diagnosed Type 2 Diabetes

    Not yet reported Chongqing Medical University 47 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT00984490

    Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery

    Not yet reported Vanderbilt-Ingram Cancer Center 5 participants Est. completion 2011-07 3 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00986401

    Safety and Tolerability of Trospium Chloride and Metformin Hydrochloride in Healthy Subjects

    Not yet reported Allergan 44 participants Est. completion 2009-11 1 site
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT00988078

    Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome

    Not yet reported Federal University of São Paulo 90 participants Est. completion 2013-12 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT00991055

    Comparison of the Efficacy and Safety Between Pioglitazone and Placebo Added to Combination Therapy in Type 2 Diabetes

    Not yet reported National Cheng-Kung University Hospital 40 participants Est. completion 2010-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00993187

    Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)

    Not yet reported Merck Sharp & Dohme LLC 292 participants Est. completion 2013-10-29
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00996658

    Linagliptin Versus Placebo in Type 2 Diabetic Patients With Inadequate Glycaemic Control on Metformin in Combination With Pioglitazone

    Not yet reported Boehringer Ingelheim 278 participants 52 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01002807

    Bioavailability Study of Fixed Dose Combination (FDC) Formulations of Dapagliflozin and Metformin XR Versus Individual Component Coadministered to Healthy Subjects in a Fasted State

    Not yet reported AstraZeneca 15 participants Est. completion 2010-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01005160

    Drug Interaction Between CKD-501 and Metformin

    Not yet reported Chong Kun Dang Pharmaceutical 24 participants Est. completion 2010-02
    Other conditions: Healthy Male Volunteers
    View official trial listing →
  • Completed NCT NCT01021579

    Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study

    Not yet reported Fasa University of Medical Sciences 84 participants Est. completion 2009-11 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01022658

    INSUlin Regimens and VASCular Functions

    Not yet reported Assistance Publique - Hôpitaux de Paris 42 participants Est. completion 2011-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01024244

    A Study of LY2599506 in Patients With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 78 participants Est. completion 2010-07 16 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01025765

    The Effects of Oral Hypoglycemic Agents on Chronic Hepatitis C Patients Receiving Peg-Intron Plus Ribavirin

    Not yet reported National Taiwan University Hospital 80 participants Est. completion 2012-12 1 site
    Other conditions: Chronic Hepatitis C
    View official trial listing →
  • Completed NCT NCT01033773

    Stop Emergency Room Visits for Hyperglycemia Project - District of Columbia (DC)

    Not yet reported Medstar Health Research Institute 86 participants Est. completion 2009-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01037660

    Effects of Lipemia and Metformin on Endothelial Function

    Not yet reported Boston University 139 participants Est. completion 2016-12-01 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01043965

    Myocardial Perfusion in Type 2 Diabetes

    Not yet reported, Not yet reported University of Sao Paulo General Hospital 61 participants Est. completion 2009-08
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01045707

    Comparison of NN5401 Versus Insulin Glargine, Both Combined With Metformin Treatment, in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 530 participants Est. completion 2010-10 92 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT01046500

    Myo-inositol Versus Metformin Administration in Post-menopausal Women With Metabolic Syndrome

    Not yet reported University of Messina 100 participants Est. completion 2014-12 1 site
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT01064687

    A Study in Participants With Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 978 participants Est. completion 2012-05 89 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01065298

    Efficacy Of Autologous Bone Marrow Derived Stem Cell Transplantation In Patients With Type 2 Diabetes Mellitus-2

    Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2011-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01075282

    A Study in Participants With Type 2 Diabetes Mellitus (AWARD-2)

    Not yet reported Eli Lilly and Company 810 participants Est. completion 2012-11 78 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01077323

    A Retrospective Cohort Study of Acute Pancreatitis in Relation to Use of Exenatide and Other Antidiabetic Agents

    AstraZeneca 363766 participants Est. completion 2008-03 1 site
    Type 2 diabetes Other conditions: Healthy Subjects (Treated With no Diabetes Therapies)
    View official trial listing →
  • Terminated NCT NCT01089790

    Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus Receiving Background Treatment With Glimepiride Alone or in Combination With Metformin or With Pioglitazone Alone

    Not yet reported Forest Laboratories 141 participants 149 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01101204

    The Effects of Hypolipemic and Antidiabetic Treatment on Cytokines

    Not yet reported Medical University of Silesia 200 participants Est. completion 2012-12 1 site
    Other conditions: Diabetes, Dyslipidemia, Inflammation, Cytokines
    View official trial listing →
  • Completed NCT NCT01106651

    A Safety and Efficacy Study of Canagliflozin in Older Patients (55 to 80 Years of Age) With Type 2 Diabetes Mellitus

    Not yet reported Janssen Research & Development, LLC 716 participants Est. completion 2013-05 86 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01107717

    Durability of Combination Therapy With Exenatide/Pioglitazone/Metformin vs. Conventional Therapy in New Onset T2DM

    Not yet reported The University of Texas Health Science Center at San Antonio 318 participants Est. completion 2023-02-03 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Withdrawn NCT NCT01107808

    Calcium, Vitamin D and Metformin to Treat Insulin Resistance in Obese African American Adolescent Females

    Not yet reported University of Alabama at Birmingham Est. completion 2011-03
    Other conditions: Insulin Resistance, Insulin Sensitivity, Obesity, Vitamin D Deficiency
    View official trial listing →
  • Completed NCT NCT01115140

    Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women

    Not yet reported University Magna Graecia 50 participants Est. completion 2011-05 1 site Stand-alone
    Other conditions: Pregnancy, Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01119846

    A Study in Type 2 Diabetics of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

    Not yet reported GlaxoSmithKline 100 participants Est. completion 2010-03-19 7 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01123980

    Comparison of the Blood Sugar Lowering Effect of Biphasic Insulin Aspart 30 and Insulin Glargine Both Combined With Metformin and Glimepiride in Chinese and Japanese Subjects With Type 2 Diabetes New to Insulin Treatment

    Not yet reported Novo Nordisk A/S 521 participants Est. completion 2011-06 34 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01125150

    Spectroscopic and Colorimetric Analysis of Acanthosis Nigricans in Patients With Hyperinsulinemia

    Henry Ford Health System 9 participants Est. completion 2012-06 1 site
    Other conditions: Acanthosis Nigricans, Hyperinsulinemia, Spectroscopic Analysis
    View official trial listing →
  • Completed NCT NCT01128621

    A Study in Type 2 Diabetic Subjects on Stable Metformin Therapy to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Co-administering Single and Multiple Oral Doses of GSK1292263

    Not yet reported GlaxoSmithKline 66 participants Est. completion 2010-04-12 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01140438

    Treatment of Latent Autoimmune Diabetes of the Adult

    Not yet reported Norwegian University of Science and Technology 64 participants Est. completion 2018-11 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01144728

    Initiation and Titration of Amaryl

    Not yet reported Sanofi 172 participants Est. completion 2010-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01144975

    Study of the Safety and Biologic Activity of XOMA 052 in Subjects With Type 2 Diabetes Mellitus

    Not yet reported XOMA (US) LLC 76 participants Est. completion 2011-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01159600

    Efficacy and Safety Study With Empagliflozin (BI 10773) vs. Placebo as add-on to Metformin or Metformin Plus Sulfonylurea Over 24 Weeks in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 1504 participants 148 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01160042

    Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fasting Condition

    Not yet reported Dr. Reddy's Laboratories Limited 54 participants Est. completion 2005-04 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT01162772

    Influence of DPP-4 on Inflammatory Parameters in Diabetics: Gender Aspects

    Medical University of Vienna 80 participants 1 site
    Type 2 diabetes Other conditions: Cardiovascular Risk, Endothelial Dysfunction
    View official trial listing →
  • Terminated NCT NCT01167738

    Combination Chemotherapy With or Without Metformin Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer

    Not yet reported IRCCS San Raffaele 60 participants Est. completion 2015-04 1 site
    Other conditions: Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT01175473

    Effects of Lixisenatide Compared to Liraglutide on the Postprandial Plasma Glucose in Patients With Type 2 Diabetes

    Not yet reported Sanofi 148 participants Est. completion 2010-11 7 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01177709

    Metformin for Weight Loss in Schizophrenia

    Not yet reported Nathan Kline Institute for Psychiatric Research 12 participants Est. completion 2011-04 1 site
    Other conditions: Schizophrenia, Obesity
    View official trial listing →
  • Completed NCT NCT01192152

    Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin/1000 mg Metformin XR (Manufactured in Mt Vernon, IN) Relative to 5 mg of Onglyza and 2 × 500 mg Glucophage XR

    Not yet reported AstraZeneca 30 participants Est. completion 2009-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01204294

    Comprehensive Add on Study in Japan

    Not yet reported Boehringer Ingelheim 574 participants Est. completion 2012-01 43 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01204580

    ADIponectin and Asymmetric Dimethylarginine (ADMA) Level in Type-2 Diabetes Patients After 12 Weeks of Treatment With GlimepiRide And Metformin Fixed Dose Combination

    Not yet reported Sanofi 40 participants Est. completion 2012-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01206153

    Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients

    Not yet reported Central South University 84 participants Est. completion 2010-03 1 site
    Other conditions: Amenorrhea
    View official trial listing →
  • Status unknown NCT NCT01206647

    Investigation of a Switch From Insulin Therapy to a Metformin & Saxagliptin Combination in Patients With Type 2 Diabetes Mellitus

    Not yet reported ikfe-CRO GmbH 120 participants Est. completion 2011-02 7 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01210001

    Efficacy and Safety of Empagliflozin (BI 10773) in Type 2 Diabetes Patients on a Background of Pioglitazone Alone or With Metformin

    Not yet reported Boehringer Ingelheim 499 participants 68 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01210911

    Metformin Combined With Chemotherapy for Pancreatic Cancer

    Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 120 participants Est. completion 2014-04 1 site
    Other conditions: Locally Advanced Pancreatic Cancer, Metastatic Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT01215331

    Gestational Diabetes: Insulin or Oral Hypoglycemic Agents?

    Not yet reported Université de Sherbrooke 73 participants Est. completion 2016-05 1 site Stand-alone
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01217073

    A Dose-Range Finding Study in Participants With Type 2 Diabetes (MK-3102-006)

    Not yet reported Merck Sharp & Dohme LLC 685 participants Est. completion 2013-04-01
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01217892

    Evaluation of Dapagliflozin Taken Twice-daily

    Not yet reported AstraZeneca 400 participants Est. completion 2011-08 55 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01219582

    GLucobay M OBservation Study for Efficacy and Safety in Treatment of Type-2 Diabetes Patients

    Bayer 9364 participants Est. completion 2012-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01221519

    A Relative Bioavailability Study Measuring the Extent and Rate of Absorption of Different Tablet Formulations of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients

    Not yet reported AstraZeneca 20 participants Est. completion 2011-01 1 site
    Type 2 diabetes Other conditions: High Blood Sugar
    View official trial listing →
  • Completed NCT NCT01224366

    Efficacy and Safety of Vildagliptin as add-on Therapy to Insulin in Patients With Type 2 Diabetes Mellitus

    Not yet reported Novartis 448 participants Est. completion 2011-10 66 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01233622

    Safety and Efficacy of Galvus as add-on Therapy to Metformin Plus Glimepiride

    Not yet reported Novartis 317 participants Est. completion 2011-11 55 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01234649

    Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)

    Not yet reported Woman's 153 participants Est. completion 2019-06-14 1 site
    Type 2 diabetesMetabolic syndromePrediabetes Other conditions: Gestational Diabetes Mellitus, Disorder of Glucose Regulation
    View official trial listing →
  • Completed NCT NCT01238978

    Phase 4 Study in the Elderly Patients With T2DM

    Not yet reported Novartis 46 participants Est. completion 2011-12 15 sites
    Type 2 diabetes Other conditions: Elderly
    View official trial listing →
  • Completed NCT NCT01241448

    A Study of LY2409021 in Patients With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 263 participants Est. completion 2012-03 40 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01241669

    Randomized, Placebo-controlled Study to Evaluate Effects of E5555 on Renal Function Parameters and OCT2 Activity

    Not yet reported Eisai Inc. 104 participants 1 site
    Other conditions: Healthy Subjects
    View official trial listing →
  • Status unknown NCT NCT01245166

    A Phase III Randomized, Double-blind, Parallel-group Study to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg Plus Acarbose 50 mg Tablets) Versus Acarbose Alone in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Lotus Pharmaceutical 220 participants Est. completion 2011-12 1 site
    Type 2 diabetes Other conditions: The Objectives of the Study is to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg, Plus Acarbose 50 mg Tablets) Thrice Daily Versus Acarbose 50 mg Thrice Daily Over 16 Weeks in
    View official trial listing →
  • Completed NCT NCT01249677

    Chronic Reduction of Fasting Glycaemia With Insulin Glargine Improves First and Second Phase Insulin Secretion in Patients With Type 2 Diabetes

    Not yet reported Ruhr University of Bochum 14 participants Est. completion 2010-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01283308

    A Randomized Trial of Diabetes Prevention Through Lifestyle Change in India

    Not yet reported Emory University 599 participants Est. completion 2013-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01286233

    Study of Biomarkers Associated With Fatigue in Patients With Early-Stage Breast Cancer Treated With Metformin or Placebo on NCIC-CTG-MA.32

    NSABP Foundation Inc 394 participants Est. completion 2016-09 256 sites
    Other conditions: Breast Cancer, Depression, Fatigue, Sleep Disorders
    View official trial listing →
  • Completed NCT NCT01289119

    Efficacy and Safety of Alogliptin in Participants With Type 2 Diabetes

    Not yet reported Takeda 506 participants Est. completion 2011-12 21 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01290575

    Multiple Ascending Dose Study of BMS-820132 in Patients With Type 2 Diabetes

    Not yet reported Bristol-Myers Squibb 67 participants Est. completion 2011-11 5 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01292993

    A Study to Evaluate the Interaction of LX4211 and Metformin in Healthy Subjects

    Not yet reported Lexicon Pharmaceuticals 18 participants 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01298518

    A Multiple Dose Study Of PF-04620110 In Type 2 Diabetes Patients

    Not yet reported Pfizer 48 participants Est. completion 2011-05 3 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01302002

    The Use of Metformin in Early Breast Cancer Patients Pre-Surgery

    Not yet reported Instituto Nacional de Cancer, Brazil Est. completion 2016-02 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Withdrawn NCT NCT01305551

    BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States

    Not yet reported AstraZeneca Est. completion 2011-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01306214

    Safety and Efficacy of BI 10773 as add-on to Insulin Regimen in Patients With Type 2 Diabetes Mellitus

    Not yet reported Boehringer Ingelheim 566 participants Est. completion 2013-04 103 sites
    Type 2 diabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT01324180

    Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 14 participants Est. completion 2017-07-27 5 sites
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT01329016

    Glyburide and Metformin for Gestational Diabetes Mellitus (GDM)

    Not yet reported, Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 177 participants Est. completion 2015-02-28 4 sites
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT01333852

    Metformin Plus Paclitaxel for Metastatic or Recurrent Head and Neck Cancer

    Not yet reported Lucas Vieira dos Santos 45 participants Est. completion 2014-04 1 site
    Other conditions: Head and Neck Neoplasms, Squamous Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01340664

    An Efficacy, Safety, and Tolerability Study of Canagliflozin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy

    Not yet reported Janssen Research & Development, LLC 279 participants Est. completion 2012-04 61 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01342042

    The Safety,Preliminary Pharmacodynamics and Pharmacokinetics Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 36 participants Est. completion 2011-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01342744

    Metformin in Postmenopausal Women With Metabolic Syndrome

    Not yet reported Mahidol University 40 participants Est. completion 2012-03 1 site
    Metabolic syndrome
    View official trial listing →
  • Withdrawn NCT NCT01352026

    Evaluation of Metformin Activity in Addition to Conventional Treatment of Grade II or III Pulmonary Arterial Hypertension (PAH)

    Not yet reported Nantes University Hospital 2 sites
    Other conditions: Pulmonary Arterial Hypertension
    View official trial listing →
  • Completed NCT NCT01357135

    An Observational Study of Type II Diabetics Treated With Dual Therapy With or Without Sitagliptin (Januvia®/Xelevia®, MK-0431-201)

    Merck Sharp & Dohme LLC 3453 participants Est. completion 2013-08-31
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01364675

    Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects

    Not yet reported Ramathibodi Hospital 8900 participants Est. completion 2016-12 1 site
    Prediabetes Other conditions: Pre-hypertension
    View official trial listing →
  • Completed NCT NCT01365091

    Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-Brazil

    Not yet reported AstraZeneca 112 participants Est. completion 2011-11 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01366391

    Therapeutic Monitoring of Metformin in Women With Polycystic Ovary Syndrome

    Not yet reported Biocinese 24 participants Est. completion 2011-10 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01381900

    A Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Alone or in Combination With a Sulphonylurea

    Not yet reported Janssen Research & Development, LLC 678 participants Est. completion 2012-11 25 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01389778

    Polycystic Ovary Syndrome Genetics and Treatment Response

    Not yet reported Massachusetts General Hospital 200 participants Est. completion 2019-10 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01396564

    Pioglitazone and Metformin in Diabetic Children

    Not yet reported, Not yet reported Coordinación de Investigación en Salud, Mexico 56 participants Est. completion 2011-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01399645

    Study of Liraglutide Versus Insulin on Liver Fat Fraction in Patients With Type 2 Diabetes

    Not yet reported Centre hospitalier de l'Université de Montréal (CHUM) 35 participants Est. completion 2014-06 1 site
    MASLDMASHType 2 diabetes
    View official trial listing →
  • Completed NCT NCT01410604

    Adipokines in Obese Adolescents With Insulin Resistance

    Not yet reported Hospital Regional de Alta Especialidad del Bajio 31 participants Est. completion 2010-03 2 sites
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT01426399

    Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of LC15-0444 and Metformin After Oral Administration in Healthy Male Subjects

    Not yet reported LG Life Sciences 30 participants Est. completion 2011-12 1 site
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT01426737

    The Swiss Glucose Variability Study

    Not yet reported University of Zurich 50 participants Est. completion 2013-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01426802

    Vildagliptin 50 mg Twice Daily in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin

    Not yet reported Novartis Pharmaceuticals 150 participants Est. completion 2011-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01427595

    Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone

    Not yet reported University of Virginia 25 participants Est. completion 2015-01-17 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Hyperandrogenism
    View official trial listing →
  • Completed NCT NCT01429506

    Efficacy of Laparoscopic Sleeve Gastrectomy and Intensive Medical Management in Obese Type 2 Diabetes

    Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2012-08 1 site
    Other conditions: Diabetes Mellitus, Obesity
    View official trial listing →
  • Completed NCT NCT01433913

    Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery

    Not yet reported National Cancer Institute (NCI) 20 participants Est. completion 2014-04 3 sites Stand-alone
    Other conditions: Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01437813

    BIOAVAILABILITY OF Glimepiride/Extended Release Metformin (GLI/METXR): High Fat Diet Study

    Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2011-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT01438190

    Metformin in Step-down Regimen Versus Conventional Low Dose Step-up Protocol in Patients With PCOS Undergoing IVF

    Not yet reported University of Modena and Reggio Emilia 120 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Infertility, PCOS
    View official trial listing →
  • Terminated NCT NCT01440127

    Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers

    Not yet reported Tufts Medical Center 9 participants Est. completion 2012-10 1 site Stand-alone
    Other conditions: Colon Cancer
    View official trial listing →
  • Completed NCT NCT01441869

    Study in Healthy Subjects to Measure Amount of Drug in Blood After Dosing With Different Saxagliptin / Metformin Produc

    Not yet reported AstraZeneca 28 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Bioequivalence, Log-transformed AUCss and Cmax,ss Values for Saxagliptin and Metformin
    View official trial listing →
  • Completed NCT NCT01443221

    Pharmacokinetics of Mitiglinide and Metformin in Free Combination and Fixed-dose Combination in Healthy Male Subjects.

    Not yet reported JW Pharmaceutical 24 participants Est. completion 2011-01 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01444248

    Compare the Compliance of Patients Treated With Once-daily (od) or Twice-daily (Bid) Glimepiride and Metformin Fixed Combination Therapy

    Not yet reported Handok Inc. 168 participants Est. completion 2012-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01455909

    A Study to Evaluate ITCA 650 Compared to Sitagliptin for the Treatment of Type 2 Diabetes

    Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01455922

    A Study to Evaluate ITCA 650 Compared to Glimepiride as Add on Therapy for the Treatment of Type 2 Diabetes

    Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01464437

    AMG 151 Amgen Protocol Number 20100761

    Not yet reported Amgen 236 participants Est. completion 2012-12 77 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01475461

    Phase 2 Study To Evaluate Safety And Efficacy Of Investigational Drug - PF04937319 In Patients With Type 2 Diabetes

    Not yet reported Pfizer 345 participants Est. completion 2013-01 63 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01476475

    Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Combination Versus Insulin Glargine Alone on Top of Metformin in Type 2 Diabetic Patients

    Not yet reported Sanofi 323 participants Est. completion 2012-12 70 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01477853

    A Study of the Co-administration of Sitagliptin and Atorvastatin in Inadequately Controlled Type 2 Diabetes Mellitus (MK-0431E-211)

    Not yet reported Merck Sharp & Dohme LLC 166 participants Est. completion 2012-12-04 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01478308

    Metformin With Standard Taxotere and Prednisone in the Treatment of Castration Resistant Prostate Cancer

    Not yet reported New Mexico Cancer Research Alliance Est. completion 2011-10
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT01482286

    Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS

    Not yet reported Pennington Biomedical Research Center 32 participants Est. completion 2016-12 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01483560

    REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL)

    Not yet reported University of Glasgow 493 participants Est. completion 2017-04-18 24 sites
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Terminated NCT NCT01496430

    Efficacy and Safety of Azilsartan Medoxomil Used in Combination With Metformin in Participants With Hypertension and Diabetes

    Not yet reported Takeda 105 participants Est. completion 2013-05 68 sites
    Other conditions: Hypertension, Diabetes
    View official trial listing →
  • Withdrawn NCT NCT01510522

    Evaluate Adherence to Treatment With Glucophage Sachets Versus Tablets in Diabetes Type 2 Patients Previously Treated With Metformin Tablets

    Not yet reported Merck KGaA, Darmstadt, Germany Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01511198

    Efficacy and Safety of Metformin and Liraglutide in Obese Subjects With Type 2 Diabetes Previously Treated With an Oral Hypoglycemic Agent

    Not yet reported Novo Nordisk A/S 223 participants Est. completion 2001-10 39 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01513590

    A Trial Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart and BIAsp 30 in Insulin naïve Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 394 participants Est. completion 2012-11-19 49 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01517373

    Study To Understand Efficacy And Safety Of Investigational Agent (PF-04937319) Compared To Approved Agent (Glimepiride) In Patients With Diabetes On Metformin

    Not yet reported Pfizer 304 participants Est. completion 2013-01 53 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01517412

    Comparison of Lixisenatide Injected Prior to the Main Meal of the Day Versus Prior to Breakfast in Type 2 Diabetic Patients on Metformin

    Not yet reported Sanofi 451 participants Est. completion 2013-05 82 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01518101

    Vildagliptin Versus Liraglutide - Patient Preference After Receiving Both Medications

    Not yet reported Novartis Pharmaceuticals 62 participants Est. completion 2012-10 8 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01519674

    Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin

    Not yet reported Novo Nordisk A/S 582 participants Est. completion 2013-10 69 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT01525225

    Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DM

    Not yet reported AstraZeneca 4 participants Est. completion 2013-06 7 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01528254

    VERIFY:A Study to Compare Combination Regimen With Vildagliptin & Metformin Versus Metformin in Treatment-naïve Patients With Type 2 Diabetes Mellitus

    Not yet reported Novartis Pharmaceuticals 2004 participants Est. completion 2019-04-04 227 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01535677

    To Compare the Similarity of a Combination Dapagliflozin/Metformin Tablet With the Two Drugs Administered Separately

    Not yet reported AstraZeneca 71 participants Est. completion 2013-07 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01540487

    Pharmacokinetics of Fixed Dose Combination (FDC) Tablets of Linagliptin /Metformin

    Not yet reported Boehringer Ingelheim 48 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01541956

    Efficacy of VIldagliptin aS an Add-on Therapy to Metformin Compared to Metformin Up-TitratION in Chinese Patients With Type 2 Diabetes.(VISION)

    Not yet reported Novartis Pharmaceuticals 3091 participants Est. completion 2013-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01544751

    Nonalcoholic Fatty Liver Disease (NAFLD) Pharmacological Treatment: Metformin Versus Atorvastatin

    Not yet reported Prof Antonino Belfiore 150 participants Est. completion 2015-06 1 site
    MASLD
    View official trial listing →
  • Completed NCT NCT01545388

    Metformin Add-on Regimen Comparison Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431A-136)

    Not yet reported Merck Sharp & Dohme LLC 337 participants Est. completion 2013-03-12 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01550900

    Prospective Trial of Metformin - Chemoprevention Role

    Not yet reported M.D. Anderson Cancer Center
    Other conditions: Colorectum
    View official trial listing →
  • Completed NCT NCT01561976

    Evaluation of Food Effect on the Pharmacokinetics of Sustained Release Metformin in Healthy Indian Volunteers

    Not yet reported GlaxoSmithKline 30 participants Est. completion 2012-02-21
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01563120

    A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus

    Not yet reported HaEmek Medical Center, Israel 108 participants Est. completion 2014-12 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT01565096

    Effect of Adding Vildagliptin on Beta Cell Function and Cardiovascular Risk Markers in Patients With Moderate Metabolic Control During Metformin Monotherapy

    Not yet reported ikfe-CRO GmbH 44 participants 1 site Stand-alone
    Other conditions: Diabetes Mellitus Type II
    View official trial listing →
  • Status unknown NCT NCT01566799

    Metformin Plus Neoadjuvant Chemotherapy in Breast Cancer

    Not yet reported Instituto Nacional de Cancerologia de Mexico 60 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: Locally Advanced Malignant Neoplasm
    View official trial listing →
  • Completed NCT NCT01573377

    Efficacy of Metformin and Diane-35 on PCOS Patients,a Randomized, Controlled, Prospective Clinical Trial

    Not yet reported Chongqing Medical University 40 participants Est. completion 2013-02 1 site
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT01573949

    A Pilot Study: Metformin Therapy in Heart Failure Patients With Early Diabetes or at High Risk of Developing Diabetes (Pre-Diabetes)

    Not yet reported University of California, Los Angeles 7 participants Est. completion 2012-12 1 site Stand-alone
    Heart failure Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01581814

    Effects of Drospirenone-ethinylestradiol and/or Metformin on Cardiovascular Risk in Hyperinsulinemic Women With Polycystic Ovary Syndrome

    Not yet reported Catholic University of the Sacred Heart 99 participants Est. completion 2012-03 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01584232

    A Study of Dulaglutide in Japanese Participants With Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 361 participants Est. completion 2013-07 15 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01587378

    Metformin to Prevent Late Miscarriage and Preterm Delivery in Women With Polycystic Ovary Syndrome

    Not yet reported Norwegian University of Science and Technology 489 participants Est. completion 2017-10-31 13 sites
    Other conditions: Pregnancy, Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01589367

    Neoadjuvant Letrozole Plus Metformin vs Letrozole Plus Placebo for ER-positive Postmenopausal Breast Cancer

    Not yet reported Seoul National University Hospital 208 participants Est. completion 2018-08 1 site
    Other conditions: Hormone Receptor Positive Malignant Neoplasm of Breast
    View official trial listing →
  • Withdrawn NCT NCT01593137

    A Long-term Trial to Compare the Effects of Liraglutide and Sulphonylurea (Glimepiride) Both in Combination With Metformin on Clinical, Endothelial and Image Markers of Cardiovascular Risk in Patients With Type 2 Diabetes

    Not yet reported Fundación Fernández-Cruz Est. completion 2014-12 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01593371

    Comparison of Metformin and Pioglitazone Effects on Adipokines Concentrations in Newly Diagnosed Type 2 Diabetes Patients

    Not yet reported Tehran University of Medical Sciences 98 participants Est. completion 2012-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01612741

    Diabetes Treatment With Glucobay in Combination With Metformin

    Bayer 19509 participants Est. completion 2009-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01624259

    A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes

    Not yet reported Eli Lilly and Company 599 participants Est. completion 2013-11 57 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01627067

    Exemestane-RAD001-Metformin

    Not yet reported M.D. Anderson Cancer Center 23 participants Est. completion 2019-02-01 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01632163

    Assessment of the Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Insufficiently Controlled With Basal Insulin +/- Metformin

    Not yet reported Sanofi 447 participants Est. completion 2015-05 51 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01649297

    A 16 Weeks Study on Efficacy and Safety of Two Doses of Empagliflozin (BI 10773) (Once Daily Versus Twice Daily) in Patients With Type 2 Diabetes Mellitus and Preexisting Metformin Therapy

    Not yet reported Boehringer Ingelheim 983 participants Est. completion 2013-12 139 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01650181

    Effects of Siliphos-Selenium-Methionine-Alpha Lipoic Acid in Patients With Fatty Liver and Non-alcoholic Steatohepatitis

    Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 50 participants Est. completion 2014-06 1 site
    Other conditions: Liver Disease
    View official trial listing →
  • Terminated NCT NCT01654640

    The Effect of Metformin on Obesity and Metabolic Disturbance in Patients Taking Clozapine

    Not yet reported Seoul National University Hospital 15 participants Est. completion 2015-04 1 site
    Other conditions: Schizophrenia
    View official trial listing →
  • Completed NCT NCT01664624

    Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 Diabetes

    Not yet reported AstraZeneca 40 participants Est. completion 2012-11 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01681693

    Effect of Genetic Variants in MATE1 and OCT3 on the Pharmacodynamics of Metformin in African Americans

    Not yet reported University of California, San Francisco 33 participants Est. completion 2013-07 1 site Stand-alone
    Type 2 diabetes Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01685762

    Metformin for the Treatment of Endometrial Hyperplasia

    Not yet reported UNC Lineberger Comprehensive Cancer Center 18 participants Est. completion 2015-12-01 3 sites
    Other conditions: Endometrial Hyperplasia, Endometrial Hyperplasia Without Atypia
    View official trial listing →
  • Completed NCT NCT01690091

    Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes

    Not yet reported, Not yet reported Institute for Clinical and Experimental Medicine 40 participants Est. completion 2016-12 1 site Stand-alone
    Heart failure Other conditions: Insulin Resistance
    View official trial listing →
  • Completed NCT NCT01710527

    BE Study of Metformin GSK 500mg

    Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-05-18
    Other conditions: Diabetic Foot
    View official trial listing →
  • Completed NCT NCT01710540

    BE Study of Metformin GSK 850mg

    Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-08
    Other conditions: Diabetic Foot
    View official trial listing →
  • Terminated NCT NCT01717482

    Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer

    Not yet reported Mayo Clinic 6 participants Est. completion 2019-05-22 1 site
    Other conditions: Lung Neoplasms, Carcinoma, Non-Small-Cell Lung
    View official trial listing →
  • Status unknown NCT NCT01717911

    ß-Cell Function and Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients With Moderate Hyperglycemia

    Not yet reported Taipei Veterans General Hospital, Taiwan 160 participants Est. completion 2018-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01726764

    Interaction Between St John's Wort and Metformin?

    Not yet reported University of Southern Denmark 20 participants Est. completion 2014-05 1 site Stand-alone
    Type 2 diabetes Other conditions: Depression
    View official trial listing →
  • Completed NCT NCT01733459

    Efficacy and Safety of DLBS3233 in Subjects With Polycystic Ovary Syndrome (PCOS)

    Not yet reported Dexa Medica Group 124 participants Est. completion 2018-06 2 sites
    Other conditions: Polycystic Ovary Syndrome (PCOS)
    View official trial listing →
  • Withdrawn NCT NCT01733836

    Prostate Cancer Active Surveillance Metformin Trial

    Not yet reported University Health Network, Toronto Est. completion 2014-10 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01754142

    Korean Post-marketing Surveillance for Kombiglyze XR®

    AstraZeneca 755 participants Est. completion 2016-09-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01755156

    A Study to Evaluate the Safety, Tolerability, and Efficacy of the Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Therapy (MK-3102-024)

    Not yet reported Merck Sharp & Dohme LLC 402 participants Est. completion 2016-03-16 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01756105

    Efficacy of Metformin in Achieving Glycaemia Goals as Recommended for the Treatment of Gestational Diabetes in Non Obese Women

    Not yet reported University Hospital, Strasbourg, France 84 participants Est. completion 2018-06 5 sites Stand-alone
    Other conditions: Gestational Diabetes, Metformin, Treatment, Oxidative Stress
    View official trial listing →
  • Completed NCT NCT01757587

    Galvus (Vildagliptin) vs Placebo in Combination With Metformin and Insulin

    Not yet reported Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète 39 participants Est. completion 2015-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01765894

    Influence of Moderate Exercise on Blood Glucose in Type 2 Diabetics and Healthy Controls

    University of Copenhagen 24 participants Est. completion 2013-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01771185

    Metabolic Effects of Gastrointestinal Surgery in T2DM

    Not yet reported University of Sao Paulo 24 participants Est. completion 2013-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01775579

    Evaluating a Pharmacokinetic Drug Interaction Between Metformin Hydrochloride and Rosuvastatin Calcium

    Not yet reported Hanmi Pharmaceutical Company Limited 36 participants Est. completion 2013-06 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01780051

    A Pharmacokinetic Study to Compare Co-administration of Repaglinide and Metformin HCl to Administration of Combination Preparation of Those Two Components

    Not yet reported Dalim BioTech Co., Ltd. 48 participants Est. completion 2013-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01786707

    Autologous Stem Cell and Hyperbaric Oxygen Therapy in Type 2 Diabetes Mellitus

    Not yet reported, Not yet reported Rodolfo Alejandro 2 participants Est. completion 2013-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01787396

    Phase III Trial to Evaluate the Efficacy and Safety of Initial Combination Therapy With Gemigliptin 50mg q.d and Metformin q.d

    Not yet reported LG Life Sciences 433 participants Est. completion 2015-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01796028

    Metformin-Docetaxel Association in Metastatic Hormone-refractory Prostate Cancer

    Not yet reported Centre Antoine Lacassagne 100 participants Est. completion 2018-05-31 1 site Stand-alone
    Other conditions: Prostatic Neoplasms
    View official trial listing →
  • Completed NCT NCT01800227

    Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fasting Conditions

    Not yet reported Torrent Pharmaceuticals Limited 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01809327

    A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise

    Not yet reported Janssen Research & Development, LLC 1186 participants Est. completion 2014-12-02 129 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01813929

    Effect of Metformin on Vascular and Mitochondrial Function in Type 1 Diabetes

    Not yet reported University of Colorado, Denver 23 participants Est. completion 2017-03-24 1 site Stand-alone
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT01825798

    Treatment of Overweight Induced by Antipsychotic Medication in Young People With Autism Spectrum Disorders (ASD)

    Not yet reported Holland Bloorview Kids Rehabilitation Hospital 60 participants Est. completion 2015-10 4 sites
    Other conditions: Overweight, Autism Spectrum Disorder
    View official trial listing →
  • Completed NCT NCT01831661

    Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fasting Condition

    Not yet reported IPCA Laboratories Ltd. 48 participants Est. completion 2013-02 1 site Stand-alone
    Other conditions: Fasting
    View official trial listing →
  • Completed NCT NCT01840007

    Pilot Study Evaluating the Efficacy and Safety of Metformin in Melanoma

    Not yet reported Centre Hospitalier Universitaire de Nice 20 participants Est. completion 2015-11-18 2 sites
    Other conditions: Metastatic Melanoma (Stage IIIC Non-résécable or no Surgically Curable or Stage IV With Classification AJCC)
    View official trial listing →
  • Completed NCT NCT01845077

    Relative Bioavailability of 2 Fixed Dose Combinations of Linagliptin/Metformin Compared With Single Tablets

    Not yet reported Boehringer Ingelheim 72 participants Est. completion 2013-08 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01845831

    Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes

    Not yet reported Emory University 292 participants Est. completion 2016-04 5 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01850615

    Efficacy and Safety of FIAsp in a Basal-bolus Regimen Versus Basal Insulin Therapy, Both in Combination With Metformin in Adult Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 323 participants Est. completion 2014-11-17 58 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT01855763

    Metformin Treatment in Gestational Diabetes and Noninsulin Dependent Diabetes in Pregnancy in a Developing Country

    Not yet reported, Not yet reported Dow University of Health Sciences 300 participants Est. completion 2013-12
    Type 2 diabetes Other conditions: Gestational Diabetes, Pregnancy
    View official trial listing →
  • Completed NCT NCT01856907

    Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM

    Not yet reported Woman's 36 participants Est. completion 2017-09-28 1 site Stand-alone
    Other conditions: Disorder of Glucose Regulation
    View official trial listing →
  • Completed NCT NCT01859793

    Effects of Sitagliptin on Endothelial Function in Type 2 Diabetes on Background Metformin Therapy

    Not yet reported Medical College of Wisconsin 38 participants Est. completion 2016-07 1 site
    Other conditions: Diabetes, Atherosclerosis
    View official trial listing →
  • Status unknown NCT NCT01864096

    The Metformin Active Surveillance Trial (MAST) Study

    Not yet reported University Health Network, Toronto 408 participants Est. completion 2024-08 12 sites Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01864174

    Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

    Not yet reported Bristol-Myers Squibb 1736 participants Est. completion 2016-06-01 156 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01869621

    Study of Metformin Pharmacogenetics in Twins

    Not yet reported University of Southern Denmark 34 participants Est. completion 2014-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01874080

    Bioequivalence Study

    Not yet reported AstraZeneca 56 participants Est. completion 2013-07 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01879293

    Metformin Reduces Left Ventricular Mass in Patients With Ischemic Heart Disease

    Not yet reported Wuhan General Hospital of Guangzhou Military Command 120 participants Est. completion 2015-08 1 site
    Other conditions: Left Ventriclar Mass
    View official trial listing →
  • Completed NCT NCT01881828

    Metformin Therapy for Overweight Adolescents With Type 1 Diabetes

    Not yet reported Jaeb Center for Health Research 164 participants Est. completion 2014-12 1 site
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT01889667

    Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Oral Bedtime Doses of ORMD-0801 in Adult Patients With Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Oramed, Ltd. 30 participants Est. completion 2013-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01890122

    Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 Diabetes

    Not yet reported Takeda 647 participants Est. completion 2015-10 45 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01890629

    Effects of Gemigliptin Versus Sitagliptin or Glimepiride With Metformin on Glucose Variability(MAGE, Glucose SD) Patients With Type 2 DM(STABLE Study)

    Not yet reported LG Life Sciences 69 participants Est. completion 2014-08 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01892020

    Investigating Efficacy and Safety of Biphasic Insulin Aspart 50 Twice Daily Versus Biphasic Human Insulin 50 Twice Daily Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus

    Not yet reported Novo Nordisk A/S 161 participants Est. completion 2014-05 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01899430

    Polycystic Ovary Syndrome and Liraglutide

    Not yet reported University Medical Centre Ljubljana 32 participants Est. completion 2013-04 1 site
    Other conditions: PCOS, Obesity
    View official trial listing →
  • Terminated NCT NCT01901224

    Metformin, Muscle Energetics, and Vascular Function in Older Adults With Peripheral Artery Disease

    Not yet reported Brigham and Women's Hospital 2 participants Est. completion 2015-06 1 site Stand-alone
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Active, not recruiting NCT NCT01905046

    Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

    Not yet reported Alliance for Clinical Trials in Oncology 86 participants Est. completion 2026-11 27 sites
    Other conditions: Atypical Ductal Breast Hyperplasia, BRCA1 Mutation Carrier, BRCA2 Mutation Carrier, Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in Situ
    View official trial listing →
  • Completed NCT NCT01907854

    Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin

    Not yet reported Novo Nordisk A/S 407 participants Est. completion 2015-06-15 106 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01915550

    Metformin as Adjuvant to Insulin Therapy in Insulin-resistant Diabetes Mellitus With Pregnancy

    Not yet reported Ain Shams University 90 participants Est. completion 2013-02 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01917656

    Efficacy and Safety of Liraglutide Versus Sulphonylurea Both in Combination With Metformin During Ramadan in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 343 participants Est. completion 2014-09-04 41 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01918865

    Safety, Tolerability, and Efficacy of ISIS-PTP1BRx in Type 2 Diabetes

    Not yet reported Ionis Pharmaceuticals, Inc. 92 participants Est. completion 2015-02 21 sites Stand-alone
    Type 2 diabetes Other conditions: Obese
    View official trial listing →
  • Terminated NCT NCT01929811

    NeoMET Study in Neoadjuvant Treatment of Breast Cancer

    Not yet reported Shanghai Jiao Tong University School of Medicine 92 participants Est. completion 2020-06 2 sites
    Other conditions: pCR Rate, BCT Rate, Safety
    View official trial listing →
  • Completed NCT NCT01929863

    Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 in Type 2 Diabetes Patients Taking Metformin

    Not yet reported GlaxoSmithKline 16 participants Est. completion 2013-11-21 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01930188

    Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 1231 participants Est. completion 2015-10-12 141 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01937598

    Antidiabetic Effects of Adding a DPP-4 Inhibitor to Pre-Existing Treatment With an Incretin Mimetic in Patients With T2D

    Not yet reported Michael A. Nauck 16 participants Est. completion 2015-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01952145

    A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide Versus Insulin Glargine in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Novo Nordisk A/S 557 participants Est. completion 2014-11-04 91 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Withdrawn NCT NCT01961388

    Study to Assess the Dietary Carbohydrate Content of Indian Diabetics With Special Therapeutic View on Effectiveness of Acarbose and Metformin Monotherapy

    Bayer Est. completion 2017-06
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01963130

    Does Vildagliptin Affect Portal Vein Pressure In Patients With Type 2 Diabetes Mellitus? A Cross Sectional Study

    Bezmialem Vakif University 97 participants Est. completion 2013-07 1 site
    Other conditions: Drug Mechanism, Drug Usage
    View official trial listing →
  • Completed NCT NCT01963663

    Metformin and Pioglitazone Effects on YKL-40 Concentrations in Type 2 Diabetes Patients

    Not yet reported Tehran University of Medical Sciences 84 participants Est. completion 2013-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01966978

    The Effect of Simple Basal Insulin Titration, Metformin Plus Liraglutide for Type 2 Diabetes With Very Elevated HbA1c - The SIMPLE Study

    Not yet reported University of Texas Southwestern Medical Center 157 participants Est. completion 2017-12 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01969318

    Efficacy and Safety Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 120 participants Est. completion 2012-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01973231

    Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 404 participants Est. completion 2014-11 61 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01973933

    Clinical Trial to Investigate the Pharmacokinetic/Pharmacodynamic Drug-Drug Interaction of Pyrimethamine and Metformin IR

    Not yet reported Seoul National University Hospital 20 participants 1 site
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT01974544

    Prevention and Treatment Of Diabetes Complications With Gastric Surgery or Intensive Medicines

    Not yet reported Pontificia Universidad Catolica de Chile 150 participants Est. completion 2016-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01980823

    Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer

    Not yet reported Columbia University 23 participants Est. completion 2022-12 1 site Stand-alone
    Other conditions: Breast Cancer, Breast Tumors, Cancer of Breast
    View official trial listing →
  • Withdrawn NCT NCT01984606

    Efficacy and Safety of Empagliflozin Versus Sitagliptin in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim Est. completion 2017-02
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01992211

    Evaluating of Pharmacokinetic Profile of BCWP_C003 and Co-administration of Rosuvastatin and Metformin

    Not yet reported BC World Pharm Co. Ltd. 35 participants Est. completion 2017-07-10 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01995032

    L-citrulline and Metformin in Duchenne's Muscular Dystrophy

    Not yet reported University Hospital, Basel, Switzerland 47 participants Est. completion 2016-03 1 site Stand-alone
    Other conditions: Duchenne's Muscular Dystrophy (DMD)
    View official trial listing →
  • Completed NCT NCT02002221

    Study of Efficacy and Safety of Vildagliptin as add-on Insulin Therapy in T2DM Patients

    Not yet reported Novartis Pharmaceuticals 156 participants Est. completion 2015-02 31 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02004886

    A Study to Assess the Safety, Tolerability and Glucose-Lowering Efficacy of MK-0893 in Participants With Type 2 Diabetes Mellitus (MK-0893-005)

    Not yet reported Merck Sharp & Dohme LLC 74 participants Est. completion 2007-02-07 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02006836

    Glycemic Responses to Majia Pomelos in Type 2 Diabetic Patients

    Not yet reported Huazhong University of Science and Technology 59 participants Est. completion 2013-12 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02027753

    Efficacy and Safety of Insulin Glargine in Patients With Type 2 Diabetes With Inadequate Control on DPP-4 Inhibitor Therapy

    Not yet reported Sanofi 109 participants Est. completion 2015-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02028221

    Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk

    Not yet reported University of Arizona 151 participants Est. completion 2022-06-14 1 site
    Other conditions: Breast Cancer Prevention
    View official trial listing →
  • Completed NCT NCT02036515

    Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

    Not yet reported Merck Sharp & Dohme LLC 464 participants Est. completion 2016-06-06 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02039245

    Multiple Dose Pharmacokinetics of Canagliflozin/Metformin 150/1,000 mg Fixed Dose Combination

    Not yet reported Janssen Research & Development, LLC 12 participants Est. completion 2014-03 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT02049034

    Lixisenatide-The Effects on Glucose and Lipid Metabolism in Type 2 Diabetes

    Not yet reported University of Surrey 8 participants Est. completion 2016-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02050074

    The Role of Metformin and Colesevelam in Human GLP-1 Secretion

    Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2014-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02053103

    A 6-Week Study To Determine The Safety And Effect Of An Investigational Drug On Adults With Type 2 Diabetes Mellitus Taking Metformin

    Not yet reported Pfizer 13 participants Est. completion 2014-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02058147

    Efficacy and Safety of Insulin Glargine/ Lixisenatide Fixed Ratio Combination Compared to Insulin Glargine Alone and Lixisenatide Alone on Top of Metformin in Patients With T2DM

    Not yet reported Sanofi 1170 participants Est. completion 2015-06 273 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02072096

    A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Eli Lilly and Company 192 participants Est. completion 2015-10 34 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02072382

    The Hypotensive Effect of Metformin in Hypertensive Patients.

    Not yet reported Hospital de Clinicas de Porto Alegre 92 participants Est. completion 2015-12 1 site Stand-alone
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT02076347

    Comparison of Two Pharmacist-led Population Management Approaches to Increase Monitoring of Vitamin B12 and Serum Creatinine Levels for Patients on Metformin

    Not yet reported Ohio State University 489 participants Est. completion 2015-10 1 site
    Type 2 diabetes Other conditions: Vitamin B12 Deficiency, Neuropathy, Anemia
    View official trial listing →
  • Completed NCT NCT02086526

    Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)

    Not yet reported Mayo Clinic 68 participants Est. completion 2016-11-20 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Active, not recruiting NCT NCT02087826

    Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS

    Not yet reported Massachusetts General Hospital 1017 participants Est. completion 2026-12 1 site
    Type 2 diabetes Other conditions: Genetics, Metabolism
    View official trial listing →
  • Completed NCT NCT02091362

    A Study of LY2409021 on Blood Pressure and Pulse Rate in Participants With Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 270 participants Est. completion 2015-01 30 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02097342

    Effect of Linagliptin on Insulin Sensitivity and Pancreatic Beta Cell Function in Patients With Type 2 Diabetes Mellitus

    Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2015-01 1 site
    Type 2 diabetes Other conditions: Insulin Sensitivity/Resistance
    View official trial listing →
  • Completed NCT NCT02100475

    A Trial Comparing Sequential Addition of Insulin Aspart Versus Further Dose Increase With Insulin Degludec/Liraglutide in Subjects With Type 2 Diabetes Mellitus, Previously Treated With Insulin Degludec/Liraglutide and Metformin and in Need of Further Intensification

    Not yet reported Novo Nordisk A/S 31 participants Est. completion 2015-04 60 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02102932

    Bioavailability of Empagliflozin/Metformin Fixed Dose Combinations (FDCs) in Healthy Chinese Volunteers

    Not yet reported Boehringer Ingelheim 96 participants Est. completion 2014-08 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02106923

    Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Extended Release (XR) Compared With Single Tablets

    Not yet reported Boehringer Ingelheim 72 participants Est. completion 2014-07 1 site
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT02115464

    Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy

    Not yet reported Ontario Clinical Oncology Group (OCOG) 54 participants Est. completion 2020-04-21 7 sites Stand-alone
    Other conditions: Lung Cancer
    View official trial listing →
  • Completed NCT NCT02119819

    A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes

    Not yet reported OPKO Health, Inc. 420 participants Est. completion 2015-10 51 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02121509

    Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/750mg) Extended Release in Healthy Subjects

    Not yet reported Boehringer Ingelheim 74 participants Est. completion 2014-07 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02125227

    Phase 1 Clinical Trial to Investigate the Effect on the Pharmacokinetics of YH14755 Compared to Co-administration of Rosuvastatin and Metformin SR in Healthy Volunteers

    Not yet reported Yuhan Corporation 56 participants Est. completion 2014-09 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT02131272

    A Trial Investigating the Efficacy and Safety of Insulin Detemir Versus Insulin NPH in Combination With Metformin and Diet/Exercise in Children and Adolescents With Type 2 Diabetes Insufficiently Controlled on Metformin With or Without Other Oral Antidiabetic Drug(s) With or Without Basal Insulin

    Not yet reported Novo Nordisk A/S 42 participants Est. completion 2016-06-14 82 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02133118

    Weight Trajectory in New Users of Sulfonylureas as Add on Therapy Next to Metformin.

    Medical Research Foundation, The Netherlands 16293 participants Est. completion 2014-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02135549

    Study of the Effectiveness and Safety of SugarDown vs. Placebo in Type 2 Diabetic Subjects Treated With Metformin

    Not yet reported Boston Therapeutics 24 participants Est. completion 2014-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02145611

    Vildagliptin vs. Glibenclamide in Endothelial Function in Type 2 Diabetes and Hypertension

    Not yet reported Dr. José Fernando Vilela-Martin MD PhD 50 participants Est. completion 2016-05 1 site
    Type 2 diabetes Other conditions: Hypertension, Endothelial Dysfunction
    View official trial listing →
  • Completed NCT NCT02147925

    Efficacy Study of Liraglutide vs.Sitagliptin vs. Glargine on Liver Fat in T2DM Subjects

    Not yet reported Sun Yat-sen University 75 participants Est. completion 2017-04 1 site
    Other conditions: Non-alcoholic Fatty Liver Disease
    View official trial listing →
  • Completed NCT NCT02157974

    Liver and Fat Regulation in Overweight Adolescent Girls

    Not yet reported, Not yet reported University of Colorado, Denver 92 participants Est. completion 2022-12 1 site
    Other conditions: Hepatic Steatosis, Polycystic Ovarian Syndrome, Obesity
    View official trial listing →
  • Completed NCT NCT02160743

    The Food Effect on Pharmacokinetics and Safety of Fixed-dose Combination of CJ-30056 in Healthy Male Subjects

    Not yet reported HK inno.N Corporation 28 participants Est. completion 2014-11 1 site Stand-alone
    Other conditions: Food Effect Study of CJ-30056 20mg/500mg
    View official trial listing →
  • Completed NCT NCT02173639

    Bioavailability of Combination Tablet BI 1356/Metformin Compared With Single BI 1356 and Metformin Administered Together to Healthy Male and Female Subjects

    Not yet reported Boehringer Ingelheim 20 participants
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02176161

    Metformin Prostate Cancer Adjuvant Trial

    Not yet reported NYU Langone Health 59 participants Est. completion 2021-07-21 1 site Stand-alone
    Other conditions: Prostate Cancer, Prostate Cancer Recurrent
    View official trial listing →
  • Completed NCT NCT02183571

    Bioequivalence Study of Two Strengths of Two Different Metformin Tablets Administered to Healthy Male and Female Subjects

    Not yet reported Boehringer Ingelheim 56 participants
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02184832

    Dietary Intake of Tryptophan and Metformin Response

    Not yet reported Massachusetts General Hospital 20 participants Est. completion 2016-03 1 site
    Other conditions: Metformin Response, Fasting Glucose, Tryptophan Concentration, Metformin Concentration, Diet Tolerability
    View official trial listing →
  • Completed NCT NCT02186847

    Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

    Not yet reported NRG Oncology 170 participants Est. completion 2025-09-04 223 sites Stand-alone
    Other conditions: Adenosquamous Lung Carcinoma, Bronchioloalveolar Carcinoma, Large Cell Lung Carcinoma, Lung Adenocarcinoma, Non-Small Cell Lung Carcinoma, Recurrent Non-Small Cell Lung Carcinoma, Squamous Cell Lung Carcinoma, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT02202161

    A Study Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 Administered With Metformin to Type 2 Diabetes Patients

    Not yet reported GlaxoSmithKline 70 participants Est. completion 2015-01-30 4 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02212756

    Pharmacokinetic Profiles of Metformin With DW1029M

    Not yet reported Dong Wha Pharmaceutical Co. Ltd. 12 participants Est. completion 2015-02 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Withdrawn NCT NCT02217670

    Comparative Bioavailability Study of Metformin HCl 1000 mg Granules vs Glucophage 1000 mg Film-coated Tablet

    Not yet reported Disphar International B.V. 1 site Stand-alone
    Other conditions: Comparative Bioavailability
    View official trial listing →
  • Completed NCT NCT02220218

    Bioequivalence Study of Metformin Component of Canagliflozin and Metformin Fixed Dose Combination Immediate Release (IR) Tablet Comparing With Metformin IR Tablet Co-administered With Canagliflozin Tablet in Healthy Fed and Fasted Participants

    Not yet reported Janssen Research & Development, LLC 2 participants Est. completion 2014-10 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02220647

    Bioequivalence of a 2.5 mg Linagliptin / 850 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 850 mg Tablets in Healthy Volunteers

    Not yet reported Boehringer Ingelheim 96 participants Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02221401

    Bioequivalence of a Linagliptin / Metformin Fixed-dose Combination (FDC) Tablet Compared With Single Linagliptin and Metformin Tablets Administered Together in Healthy Volunteers

    Not yet reported Boehringer Ingelheim 96 participants Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02221414

    Bioequivalence of a 2.5 mg Linagliptin / 500 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 500 mg Tablets Administered Together in Healthy Volunteers

    Not yet reported Boehringer Ingelheim 95 participants
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02223026

    Relative Bioavailability of a Linagliptin+Metformin Fixed Dose Combination Tablet Administered With and Without Food to Healthy Male and Female Subjects

    Not yet reported Boehringer Ingelheim 32 participants
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02226510

    MetfoRmin and Its Effects on Left Ventricular Hypertrophy in Normotensive Patients With Coronary Artery Disease

    Not yet reported University of Dundee 68 participants Est. completion 2017-12 1 site
    Cardiovascular diseasePrediabetes Other conditions: Left Ventricular Hypertrophy, Insulin Resistance
    View official trial listing →
  • Withdrawn NCT NCT02229240

    Albiglutide Versus Placebo Added-on to Basal-Bolus Insulin Therapy in Subjects With Type 2 Diabetes Mellitus

    Not yet reported GlaxoSmithKline Est. completion 2015-12
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02244164

    Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments.

    Not yet reported Erasme University Hospital 5 participants Est. completion 2023-02-13 1 site
    Type 2 diabetes Other conditions: Incretinomimetics, Pancreas
    View official trial listing →
  • Status unknown NCT NCT02244567

    Effect of Metformin Therapy on Serum Under-carboxylated Osteocalcin Levels in Hyperandrogenic Lean Polycystic Ovarian Syndrome Women

    Not yet reported Beni-Suef University 100 participants Est. completion 2021-06 1 site
    Other conditions: Polycystic Ovarian Syndrome
    View official trial listing →
  • Completed NCT NCT02249910

    Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Metformin and Digoxin in Healthy Subjects

    Not yet reported Novo Nordisk A/S 32 participants Est. completion 2015-03-06 1 site Added to GLP-1
    Other conditions: Diabetes, Healthy
    View official trial listing →
  • Completed NCT NCT02252965

    Metformin Extended Release Versus Metformin Immediate Release in Subjects With Type 2 Diabetes

    Not yet reported Merck KGaA, Darmstadt, Germany 532 participants Est. completion 2016-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02266472

    Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Male and Female

    Not yet reported Boehringer Ingelheim 30 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02275845

    Medico-GDM Trial - Metformine to Prevent Gestational Diabetes Mellitus

    Not yet reported Maasstad Hospital 400 participants Est. completion 2017-09 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT02279758

    A Pilot Study of Metformin Treatment in Patients With Well-differentiated Neuroendocrine Tumors

    Not yet reported Instituto do Cancer do Estado de São Paulo 30 participants 1 site
    Other conditions: Well-differentiated Neuroendocrine Tumors
    View official trial listing →
  • Completed NCT NCT02283554

    Platelet Rich Fibrin With 1% Metformin Gel for Treatment of Intrabony Defects

    Not yet reported Government Dental College and Research Institute, Bangalore 120 participants
    Other conditions: Periodontitis
    View official trial listing →
  • Completed NCT NCT02288273

    Study to Evaluate the Effect of BYDUREON on 24-hour Glucose Control in Metformin Treated Patients With Type 2 Diabetes.

    Not yet reported AstraZeneca 239 participants Est. completion 2015-08 29 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02294006

    Activity and Safety of Everolimus+Octreotide LAR+Metformin in Advanced Pancreatic Well-differentiated NETs

    Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 26 participants Est. completion 2021-10 1 site Stand-alone
    Other conditions: Well Differentiated Pancreatic Endocrine Tumor
    View official trial listing →
  • Completed NCT NCT02298192

    A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration Algorithms

    Not yet reported Novo Nordisk A/S 420 participants Est. completion 2015-12-23 84 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02304081

    Saxagliptin in Combination With Dapagliflozin - Effects on Islet Cell Function

    Not yet reported Prof. Dr. Thomas Forst 64 participants Est. completion 2016-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT02336087

    Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery

    Not yet reported City of Hope Medical Center 21 participants Est. completion 2026-12-09 4 sites
    Other conditions: Pancreatic Adenocarcinoma, Unresectable Pancreatic Carcinoma, Stage III Pancreatic Cancer AJCC v6 and v7, Stage IV Pancreatic Cancer AJCC v6 and v7
    View official trial listing →
  • Completed NCT NCT02338921

    Triple Combination Therapy in Type 2 Diabetic Patients Who Had Inadequate Glycemic Control With Combination Therapy

    Not yet reported Seoul National University Bundang Hospital 78 participants Est. completion 2021-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02339168

    Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer

    Not yet reported University of California, Davis 25 participants Est. completion 2025-02-24 1 site Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT02341703

    Ovulation Induction in Clomiphene Citrate Resistant PCO Women

    Not yet reported Cairo University 100 participants Est. completion 2015-07 1 site
    Other conditions: Polycystic Ovary Syndrome, Infertility
    View official trial listing →
  • Completed NCT NCT02367066

    A Phase I Study to Assess the Pharmacodynamics of Oral AR-C165395XX in Subjects With Type 2 Diabetes Mellitus (T2DM)

    Not yet reported AstraZeneca 30 participants Est. completion 2015-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02368704

    Role of Endoplasmic Reticulum Stress in the Pathophysiology of Type 2 Diabetes

    Assistance Publique - Hôpitaux de Paris 40 participants Est. completion 2016-11 1 site
    Type 2 diabetes Other conditions: Endoplasmic Reticulum Stress
    View official trial listing →
  • Completed NCT NCT02372656

    Simvastatin and Metformin in Chronic Periodontitis

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 98 participants Est. completion 2014-08
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Status unknown NCT NCT02383563

    Metformin for HIV Inflammation

    Not yet reported University of Hawaii 12 participants Est. completion 2016-02 1 site
    Cardiovascular disease Other conditions: HIV
    View official trial listing →
  • Status unknown NCT NCT02394158

    Preventing Recurrent Gestational Diabetes With Metformin

    Not yet reported Imperial College London 112 participants Est. completion 2019-09-30 2 sites
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02394652

    The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized Trial

    Not yet reported University Health Network, Toronto 16 participants Est. completion 2021-01-12 5 sites Stand-alone
    Other conditions: Uterine Cervical Neoplasms, Squamous Cell Carcinoma, Adenocarcinoma, Carcinoma, Adenosquamous
    View official trial listing →
  • Completed NCT NCT02401880

    Effects of Linagliptin in Addition to Empagliflozin on Islet Cell Physiology

    Not yet reported Profil Institut für Stoffwechselforschung GmbH 89 participants Est. completion 2015-12 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02405260

    Add Glucokinase Activator to Target A1c

    Not yet reported vTv Therapeutics 190 participants Est. completion 2016-09 20 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02407899

    Protective Effects of Saxagliptin (And Vitamin D3) on β Cell Function in Adult-onset Latent Autoimmune Diabetes

    Not yet reported Second Xiangya Hospital of Central South University 300 participants Est. completion 2020-12-31 39 sites Stand-alone
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT02411825

    Multiple Ascending Dose Study in Healthy Male Subjects and Overweight to Obese Male and Female Type 2 Diabetes Mellitus (T2DM) Patients

    Not yet reported Sanofi 76 participants Est. completion 2016-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02417090

    Late Metabolic Effects of Metformin Therapy in Gestational Diabetes

    Turku University Hospital 173 participants Est. completion 2019-12-01
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT02420262

    A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Novo Nordisk A/S 506 participants Est. completion 2016-10-05 117 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT02426294

    Comparison of Pioglitazone Versus Glimepiride in Type 2 Diabetes Inadequately Controlled With Metformin Plus Alogliptin

    Not yet reported Pusan National University Hospital 154 participants Est. completion 2016-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02431676

    Survivorship Promotion In Reducing IGF-1 Trial

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 121 participants Est. completion 2018-12 1 site Stand-alone
    Other conditions: Breast Cancer, Prostate Cancer, Lung Cancer, Colon Cancer, Melanoma of Skin, Endometrial Cancer, Liver Cancer, Pancreatic Cancer, Rectal Cancer, Kidney Cancer, Other Solid Malignant Tumors
    View official trial listing →
  • Completed NCT NCT02437656

    Combination of Metformin to Neoadjuvant Radiochemotherapy in the Treatment of Locally Advanced Rectal Cancer.

    Not yet reported Centre Oscar Lambret 60 participants Est. completion 2017-03 11 sites
    Other conditions: Rectal Cancer
    View official trial listing →
  • Completed NCT NCT02440893

    Understanding the Effect of Metformin on Corus CAD (or ASGES)

    CardioDx 37 participants Est. completion 2014-06
    Cardiovascular disease Other conditions: Angina Pectoris, Chest Pain, Coronary Heart Disease, CAD, CVD, CHD
    View official trial listing →
  • Completed NCT NCT02471404

    Efficacy and Safety of Dapagliflozin and Dapagliflozin Plus Saxagliptin in Combination With Metformin in Type 2 Diabetes Patients Compared With Sulphonylurea

    Not yet reported AstraZeneca 939 participants Est. completion 2017-03-13 173 sites
    Type 2 diabetes Other conditions: Inadequate Glycaemic Control
    View official trial listing →
  • Terminated NCT NCT02473094

    Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer

    Not yet reported University of Campinas, Brazil 3 participants Est. completion 2016-02 1 site Stand-alone
    Other conditions: Rectal Neoplasms, Adenocarcinoma, Carcinoma
    View official trial listing →
  • Status unknown NCT NCT02480465

    Efficacy and Safety of Lobeglitazone Versus Sitagliptin

    Not yet reported Chong Kun Dang Pharmaceutical 248 participants Est. completion 2017-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02488564

    A Study of Liposomal Doxorubicin+Docetaxel+Trastuzumab+Metformin in Operable and Locally Advanced HER2 Positive Breast Cancer

    Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 49 participants Est. completion 2020-03-17 9 sites
    Other conditions: HER-2 Positive Breast Cancer
    View official trial listing →
  • Completed NCT NCT02496000

    Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus

    Not yet reported Oramed, Ltd. 188 participants Est. completion 2016-09-13 34 sites
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT02496741

    Metformin And Chloroquine in IDH1/2-mutated Solid Tumors

    Not yet reported, Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 15 participants Est. completion 2019-11-18 3 sites
    Obstructive sleep apnea Other conditions: Glioma, Cholangiocarcinoma
    View official trial listing →
  • Completed NCT NCT02497313

    Effect of Metformin and Cholecystokinin-mediated Gallbladder Emptying on GLP-1 Secretion in Type 2 Diabetes

    Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2016-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02500628

    Heart Rate Variability in Response to Metformin Challenge

    Not yet reported Woodinville Psychiatric Associates 61 participants Est. completion 2016-02 1 site Stand-alone
    Type 2 diabetes Other conditions: Fibromyalgia, Mitochondrial Diseases, Movement Disorders
    View official trial listing →
  • Status unknown NCT NCT02502344

    Effect of Medical Interventions in Insulin Resistance on Prevalence of Abnormal Glucose Tolerance

    Not yet reported Beijing Tsinghua Chang Gung Hospital 60 participants 1 site
    Other conditions: Insulin Resistance
    View official trial listing →
  • Completed NCT NCT02514629

    Testosterone, Metformin, or Both, for Hypogonadism in Obese Males

    Not yet reported Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud 107 participants Est. completion 2016-07-12 1 site Stand-alone
    Other conditions: Hypogonadism, Obesity
    View official trial listing →
  • Completed NCT NCT02524821

    The Effect of Gelesis100 on the Pharmacokinetics of Metformin

    Not yet reported Gelesis, Inc. 24 participants Est. completion 2015-12 1 site
    Other conditions: Healthy Overweight Obese
    View official trial listing →
  • Completed NCT NCT02526524

    Dose-Ranging Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Metformin Delayed Release in Subjects With T2DM

    Not yet reported Elcelyx Therapeutics, Inc. 571 participants Est. completion 2016-09 137 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02535299

    Par-4 and Telomere-telomerase System in Type 2 Diabetes Patients Who Received GLP-1 or Metformin Treatment

    Not yet reported Third Military Medical University 200 participants Est. completion 2019-12 1 site
    Other conditions: GLP-1;Metformin;Telomere-telomerase System;Par-4
    View official trial listing →
  • Status unknown NCT NCT02535975

    The Effects of Metformin in Patients With Mild Graves' Ophthalmopathy

    Not yet reported Yonsei University 80 participants Est. completion 2019-10 1 site
    Other conditions: Mild Graves' Ophthalmopathy
    View official trial listing →
  • Completed NCT NCT02551874

    A 24-week Open-Label, Phase 3b Trial With a 28-week Extension to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin Compared to Insulin Glargine in Subjects withType 2 Diabetes Who Have Glycemic Control on Metformin

    Not yet reported AstraZeneca 650 participants Est. completion 2017-11-10 40 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02570672

    Metformin for Preventing Frailty in High-risk Older Adults

    Not yet reported The University of Texas Health Science Center at San Antonio 141 participants Est. completion 2024-02-07 1 site
    Other conditions: Frailty
    View official trial listing →
  • Completed NCT NCT02580331

    1% Metformin Gel in the Treatment of Class II Furcation Defects

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 64 participants Est. completion 2015-09 1 site
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Completed NCT NCT02586129

    Clinical Trial of YH14755 in Subjects With Dyslipidemia and Type II Diabetes

    Not yet reported Yuhan Corporation 249 participants Est. completion 2017-07-07 1 site
    Other conditions: Dyslipidemia, Type II Diabetes
    View official trial listing →
  • Completed NCT NCT02586636

    Impact of OCT1 on Metformin Tolerance

    Not yet reported NHS Tayside 61 participants Est. completion 2018-04-09 1 site
    Other conditions: Tolerance
    View official trial listing →
  • Status unknown NCT NCT02587741

    Comparison of Diabetes Retinopathy Among Type 2 Diabetic Patients Treated With Different Regimens

    Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 600 participants Est. completion 2025-07 1 site Stand-alone
    Other conditions: Diabetic Retinopathy
    View official trial listing →
  • Completed NCT NCT02588859

    Study to Understand Usage and Effect of Saxagliptin as First Add-On After Metformin in Indian Type 2 Diabetes Mellitus Patients

    AstraZeneca 1200 participants Est. completion 2016-12-26 31 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02597101

    Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes

    Not yet reported Nick Giannoukakis, PhD 14 participants Est. completion 2019-06-15 1 site Stand-alone
    Type 2 diabetes Other conditions: Insulin Resistance
    View official trial listing →
  • Completed NCT NCT02607410

    Sitagliptin (DPP-4 Inhibitor) and NPH Insulin in Patients With T2D

    Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2014-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02627898

    Effect of Green Tea Extract on Arterial Stiffness in Type 2 Diabetes Mellitus

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2016-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02629627

    Conjugated Linoleic Acid / Leucine Versus Metformin on Visceral Fat in Metabolic Syndrome

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 104 participants Est. completion 2017-10 Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT02630706

    A Study to Evaluate the Efficacy and Safety of Ertugliflozin in Asian Participants With Type 2 Diabetes and Inadequate Glycemic Control on Metformin Monotherapy (MK-8835-012)

    Not yet reported Merck Sharp & Dohme LLC 506 participants Est. completion 2017-12-27
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02638805

    Study of the Safety and Tolerability of Switching to ITCA 650 in Patients With Type 2 Diabetes Receiving Liraglutide

    Not yet reported Intarcia Therapeutics 136 participants Est. completion 2017-10 36 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02670018

    BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 2000mg in Comparison to Each Component Administered Alone

    Not yet reported LG Life Sciences 25 participants Est. completion 2016-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02672488

    Metformin Plus Sorafenib for Advanced HCC

    Not yet reported Tianjin Medical University Cancer Institute and Hospital 82 participants Est. completion 2018-12 1 site
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT02693392

    Clinical Evaluation of Fenugreek Seed Extract, a Nutraceutical in Patients With Type- 2 Diabetes

    Not yet reported All India Institute of Medical Sciences, Bhubaneswar 200 participants Est. completion 2018-08-16 1 site Stand-alone
    Other conditions: Type-2 Diabetes Mellitus
    View official trial listing →
  • Withdrawn NCT NCT02694289

    Effects of Metformin in Heart Failure Patients

    Not yet reported Maya Guglin Est. completion 2018-09-10
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT02719132

    Effect of DapagliFLOzin on Quality of Life in Patients With Type 2 Diabetes in a Real Clinical PrActice

    Not yet reported AstraZeneca Est. completion 2017-11
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02738879

    Randomized Sitagliptin Withdrawal Study (MK-0431-845)

    Not yet reported Merck Sharp & Dohme LLC 746 participants Est. completion 2018-01-30
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02741960

    The Effect of Metformin on Reducing Lupus Flares

    Not yet reported RenJi Hospital 180 participants Est. completion 2018-12-07 1 site
    Other conditions: Systemic Lupus Erythematosus
    View official trial listing →
  • Completed NCT NCT02751307

    Adjunctive Low-dose Metformin in Patients With Schizophrenia and Metabolic Abnormalities

    Not yet reported Taipei Medical University WanFang Hospital 55 participants Est. completion 2015-01
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT02752113

    Effects of Empagliflozin + Linagliptin vs Metformin + Insulin Glargine on Renal and Vascular Changes in Type 2 Diabetes

    Not yet reported Institut für Pharmakologie und Präventive Medizin 101 participants Est. completion 2019-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02752412

    Efficacy and Safety of LixiLan Versus Insulin Glargine Alone Both With Metformin in Japanese With Type 2 Diabetes Mellitus Inadequately Controlled on Basal Insulin and Oral Antidiabetic Drugs

    Not yet reported Sanofi 513 participants Est. completion 2018-10-04 122 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02760342

    A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Metformin

    Not yet reported Astellas Pharma Inc 24 participants Est. completion 2016-06-26 1 site Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT02765347

    The Effects of Metformin on Glycemic Control and Insulin Sensitivity in Adolescents With T1DM

    Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 30 participants Est. completion 2018-01 1 site
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT02773927

    Combination of Metformin/Inulin vs Inulin on Adiponectin in Metabolic Syndrome

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 40 participants Est. completion 2015-06 1 site Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT02778776

    Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic Syndrome

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 40 participants Est. completion 2015-06 1 site Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT02786823

    Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes

    Not yet reported, Not yet reported All India Institute of Medical Sciences, Bhubaneswar 80 participants Est. completion 2017-09-15 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02793505

    Safety of Metformin in Pregnancy

    Centre Hospitalier Universitaire Vaudois 950 participants
    Other conditions: Pregnancy, Pregestational Diabetes, Polycystic Ovary Syndrom
    View official trial listing →
  • Completed NCT NCT02794792

    A Study to Assess the Efficacy and Safety of Ipragliflozin in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin

    Not yet reported Astellas Pharma Europe B.V. 268 participants Est. completion 2017-06-20 14 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02802215

    Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome

    Not yet reported, Not yet reported Ain Shams University 80 participants Est. completion 2016-09 1 site
    Other conditions: Polycystic Ovary Syndrome, Diabetes, Gestational
    View official trial listing →
  • Completed NCT NCT02803918

    A Study on Safety, Pharmacokinetics and Pharmacodynamics of Lixisenatide in Pediatric Patients With Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Sanofi 23 participants Est. completion 2020-01-27 11 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02813863

    The Drug-drug Interaction of SP2086 and Metformin

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 24 participants
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02821910

    Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Linagliptin/Metformin Extended Release Compared With Single Tablets

    Not yet reported Boehringer Ingelheim 50 participants Est. completion 2016-10-31 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02823691

    The MetNET-2 Trial

    Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 20 participants Est. completion 2021-12 1 site Stand-alone
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Status unknown NCT NCT02823808

    Effect of Alogliptin/Pioglitazone on the Preservation of Long-term Beta-cell Function

    Not yet reported Kyunghee University Medical Center 96 participants Est. completion 2021-12 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02831361

    Trial to Evaluate the Efficacy and Safety of Gemigliptin Compared With Placebo Added on Insulin Alone or on Insulin in Combination With Metformin in Type 2 DM (ZEUS II Study)

    Not yet reported LG Life Sciences 290 participants Est. completion 2018-02-08 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02853630

    A Clinical Trial to Study the Effects of Two Drugs, Vildagliptin and Metformin in Patients With Type 2 Diabetes Mellitus

    Not yet reported India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals 203 participants Est. completion 2018-12 6 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02865668

    A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

    Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-10 1 site
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT02874430

    Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 29 participants Est. completion 2020-12-11 1 site
    Obstructive sleep apnea Other conditions: Breast Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Uterine Corpus Cancer
    View official trial listing →
  • Completed NCT NCT02875821

    Effects of Ipragliflozin on Excessive Fat in Type 2 Diabetes Patients With Non-alcoholic Fatty Liver Disease Treated With Metformin and Pioglitazone

    Not yet reported Yonsei University 44 participants Est. completion 2017-06-07 1 site
    MASLDType 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT02879409

    HbA1c Variability in Type II Diabetes

    Not yet reported Weill Cornell Medical College in Qatar 150 participants Est. completion 2026-10-01 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02882477

    Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based Therapy

    Not yet reported, Not yet reported Hadassah Medical Organization 20 participants Est. completion 2018-12 1 site
    Other conditions: Diabetes Mellitus, Iron Metabolism Disorders, Gastroduodenal Ulcer, Optic Atrophy, Sensorineural Hearing Loss, Platelet Dysfunction
    View official trial listing →
  • Completed NCT NCT02884089

    A Study of the Effect of Abemaciclib on Metformin and Iohexol in Healthy Participants

    Not yet reported Eli Lilly and Company 40 participants Est. completion 2016-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02887625

    Exenatide Plus Pioglitazone Versus Insulin in Poorly Controlled T2DM

    Not yet reported Dr. Muhammad Abdulghani 410 participants Est. completion 2017-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02895750

    Efficacity and Safety of Metformin XR in CKD Stage 1 to 3

    Not yet reported Centre Hospitalier Universitaire, Amiens 12 participants Est. completion 2022-10-10 1 site Stand-alone
    Other conditions: Renal Insufficiency, Chronic
    View official trial listing →
  • Completed NCT NCT02909933

    Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of Obesity

    Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2015-10 1 site Added to GLP-1
    Other conditions: Polycystic Ovary Syndrome, Obesity
    View official trial listing →
  • Completed NCT NCT02911792

    Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With Hyperfiltration

    Not yet reported The University of Texas Health Science Center at San Antonio 72 participants Est. completion 2023-07-11 2 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02932475

    Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD)

    Not yet reported University of North Carolina, Chapel Hill 831 participants Est. completion 2022-06-15 10 sites
    Other conditions: Diabetes, Pregnancy
    View official trial listing →
  • Completed NCT NCT02941445

    Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss

    Not yet reported University Medical Centre Ljubljana 24 participants Est. completion 2016-08 Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Body Weight
    View official trial listing →
  • Terminated NCT NCT02945813

    SAKK 08/15 - PROMET - Salvage Radiotherapy +/- Metformin for Patients With Prostate Cancer After Prostatectomy

    Not yet reported Swiss Cancer Institute 112 participants Est. completion 2022-02-28 27 sites Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT02947620

    Metformin/Atorvastatin Combination Therapy in Subjects With Type II Diabetes and Dyslipidemia (Phase 3)

    Not yet reported Daewoong Pharmaceutical Co. LTD. 185 participants Est. completion 2017-02-27 1 site
    Other conditions: Type II Diabetes, Dyslipidemia
    View official trial listing →
  • Completed NCT NCT02954692

    A Study to Evaluate the Effectiveness and Safety Initiation and Titration of Insulin Glargine (U300) in Insulin-naïve Patients With Type 2 Diabetes Mellitus (T2DM) Controlled on Oral Antidiabetic Drug Treatment in Turkey

    Not yet reported Sanofi 112 participants Est. completion 2017-12-22 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02964247

    LIRA-ADD2SGLT2i - Liraglutide Versus Placebo as add-on to SGLT2 Inhibitors.

    Not yet reported Novo Nordisk A/S 303 participants Est. completion 2018-05-08 82 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT02967276

    Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma

    Not yet reported University of Campinas, Brazil 28 participants Est. completion 2020-02 2 sites Stand-alone
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT02980276

    RCT Metformin for Reduction of Gestational Diabetes Mellitus Effects

    Not yet reported National University of Ireland, Galway, Ireland 535 participants Est. completion 2023-04-13 2 sites
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT02981329

    Fetal Hemoglobin Induction Treatment Metformin

    Not yet reported Baylor College of Medicine 37 participants Est. completion 2020-07-20 2 sites
    Other conditions: Sickle Cell Anemia, Sickle Cell Disease, Hemoglobin Disorder
    View official trial listing →
  • Completed NCT NCT02986659

    Genomic Outcomes of Metformin

    Not yet reported Wake Forest University Health Sciences 30 participants Est. completion 2018-11-15 1 site
    Cardiovascular disease Other conditions: Mild Cognitive Impairment, Obesity, Abdominal, Hypertension
    View official trial listing →
  • Completed NCT NCT03017833

    Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers

    Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2022-12-21 1 site Stand-alone
    Other conditions: Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory Neoplasm
    View official trial listing →
  • Status unknown NCT NCT03029390

    Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes

    Not yet reported University of Guadalajara 28 participants Est. completion 2023-12 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT03029702

    Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus

    Not yet reported Maisa N. Feghali, MD 54 participants Est. completion 2023-08-31 1 site
    Other conditions: Gestational Diabetes, Diabetes, Gestational, Pregnancy in Diabetes
    View official trial listing →
  • Completed NCT NCT03030300

    Remission Rate of Newly Diagnosed Type 2 Diabetes Outpatients Treated With Short-term Intensive Insulin Therapy

    Not yet reported Qianfoshan Hospital 170 participants Est. completion 2015-02 3 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03031821

    Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome

    Not yet reported Canadian Urologic Oncology Group 166 participants Est. completion 2023-11-24 16 sites Stand-alone
    Metabolic syndrome Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT03041129

    Post-Prandial Liver Glucose Metabolism in PCOS

    University of Colorado, Denver 19 participants Est. completion 2018-09-29 1 site
    Other conditions: Polycystic Ovarian Syndrome, Obesity, Hepatic Steatosis
    View official trial listing →
  • Status unknown NCT NCT03048500

    Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

    Not yet reported Northwestern University 17 participants Est. completion 2021-09 2 sites
    Other conditions: Recurrent Non-Small Cell Lung Carcinoma, Stage III Non-Small Cell Lung Cancer, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung Cancer, Stage IV Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT03049228

    In and ex Vivo Mitochondrial Function of the Heart

    Maastricht University Medical Center 38 participants Est. completion 2020-03-02 1 site
    Type 2 diabetes Other conditions: Diabetic Cardiomyopathies
    View official trial listing →
  • Suspended NCT NCT03051451

    Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity

    Not yet reported Laboratorios Silanes S.A. de C.V. 150 participants Est. completion 2018-11 1 site
    Other conditions: Overweight and Obesity
    View official trial listing →
  • Completed NCT NCT03061214

    Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT)

    Not yet reported Novo Nordisk A/S 868 participants Est. completion 2019-04-15 67 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT03088670

    Efficacy and Safety of Gosogliptin as Monotherapy and in Combination With Metformin vs. Vildagliptin as Monotherapy and in Combination With Metformin in Drug-naive Type 2 Diabetic Patients.

    Not yet reported SatRx LLC 299 participants Est. completion 2014-10-03 27 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03108963

    L-carnitine and Metformin in Obese PCOS Women.

    Not yet reported Zagazig University 280 participants Est. completion 2018-03 1 site
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT03109873

    Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 9 participants Est. completion 2020-07-31 1 site Stand-alone
    Other conditions: Larynx, Lip, Oral Cavity, Pharynx
    View official trial listing →
  • Completed NCT NCT03117517

    Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome

    Not yet reported Khyber Medical University Peshawar 106 participants Est. completion 2018-03-07 1 site Stand-alone
    Other conditions: Polycystic Ovarian Syndrome
    View official trial listing →
  • Terminated NCT NCT03118713

    A Study to Evaluate the Renal Protective Effect (Urine Albumin-to-Creatinine Ratio (UACR)), Efficacy and Safety of Ipragliflozin in Type 2 Diabetes Mellitus Patients With Albuminuria

    Not yet reported Astellas Pharma Korea, Inc. 33 participants Est. completion 2018-12-12 8 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03122769

    Cardiac Uptake of Metformin, Visualized by Positron Emission Tomography

    Not yet reported Henrik Wiggers 6 participants Est. completion 2018-04-10 1 site Stand-alone
    Heart failure
    View official trial listing →
  • Completed NCT NCT03130426

    Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IGlarLixi

    Not yet reported Population Health Research Institute 161 participants Est. completion 2020-09-30 8 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03137186

    Repurposing Metformin as Anticancer Drug: in Advanced Prostate Cancer

    Not yet reported Mansoura University 120 participants Est. completion 2020-01 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT03141073

    Long-term Efficacy and Safety of HMS5552 add-on to Metformin in T2DM Subjects

    Not yet reported Hua Medicine Limited 767 participants Est. completion 2021-02-28 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03151005

    The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS

    Not yet reported Xinqiao Hospital of Chongqing 70 participants Est. completion 2021-04-23 1 site
    Other conditions: Polycystic Ovary Syndrome (PCOS), Overweight, Obesity
    View official trial listing →
  • Completed NCT NCT03167918

    Lung Function in Patients With Early Type 2 Diabetes Mellitus

    Not yet reported, Not yet reported Liaoning University of Traditional Chinese Medicine 200 participants Est. completion 2017-05-01 Stand-alone
    Type 2 diabetes Other conditions: Pulmonary Function
    View official trial listing →
  • Status unknown NCT NCT03184493

    Celebrex and Metformin for Postoperative Hepatocellular Carcinoma

    Not yet reported Guangxi Medical University 200 participants Est. completion 2021-06 1 site Stand-alone
    Other conditions: Liver Cancer
    View official trial listing →
  • Completed NCT NCT03189407

    Effect of Moringa Oleifera on Metformin Plasma Level in Type 2 Diabetes Mellitus Patients

    Not yet reported Titilayo O Fakeye 25 participants Est. completion 2016-04-30
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03189732

    Effect of Metformin on Exercise-induced Lipolysis

    Not yet reported Charles University, Czech Republic 10 participants Est. completion 2018-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03192293

    Metformin and Simvastatin in Addition to Fulvestrant

    Not yet reported National University Hospital, Singapore 28 participants Est. completion 2019-01-20 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT03194009

    PRuDENTE; Diabetes Prevention Via Exercise, Nutrition and Treatment

    Not yet reported Instituto Nacional de Salud Publica, Mexico 3060 participants Est. completion 2022-12-31 1 site
    Type 2 diabetes Other conditions: Prediabetic State
    View official trial listing →
  • Completed NCT NCT03204058

    Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 90 participants Est. completion 2017-02-23
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Completed NCT NCT03204071

    Locally Delivered Metformin and Aloe Vera for Treatment of Intrabody Defects in Chronic Periodontitis

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 90 participants Est. completion 2017-02
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Status unknown NCT NCT03204799

    Metagenomic Analysis of Human Gut Microbiota in Patients With Metabolic Diseases Including Diabetes

    Yonsei University 150 participants Est. completion 2019-12-16 1 site
    Type 2 diabetes Other conditions: Dyslipidemias
    View official trial listing →
  • Completed NCT NCT03214380

    A Study of LY900014 Compared to Insulin Lispro in Participants With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 933 participants Est. completion 2019-03-13 141 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03225209

    Medically Reproducing Bariatric Surgery

    Not yet reported Moahad S Dar 5 participants Est. completion 2018-10-23 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03235050

    A Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 834 participants Est. completion 2019-06-14 119 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03236740

    OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS

    Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2018-03-15 1 site
    Other conditions: PCOS
    View official trial listing →
  • Status unknown NCT NCT03239119

    The Effectivity and Safety Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 456 participants Est. completion 2019-01-15
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03283657

    Diabetes Risk Education and Communication Trial

    Not yet reported Northwestern University 53 participants Est. completion 2019-03-17 1 site
    PrediabetesType 2 diabetes Other conditions: Diabetes Mellitus, Body Weight, Body Weight Changes
    View official trial listing →
  • Completed NCT NCT03312582

    Locally Delivered 1% Metformin Gel in Peri-implantitis

    Not yet reported King Saud University 46 participants Est. completion 2017-07-24
    Other conditions: Peri-Implantitis
    View official trial listing →
  • Terminated NCT NCT03349775

    Cardiometabolic Disease and Pulmonary Hypertension

    Not yet reported Massachusetts General Hospital 21 participants Est. completion 2020-12-22 1 site
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT03364335

    The Effect Of NS-0200 and NS-0300 Versus Placebo on Weight In Obesity

    Not yet reported NuSirt Biopharma 267 participants Est. completion 2018-08-17 15 sites
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT03378297

    IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC

    Not yet reported Haukeland University Hospital 26 participants Est. completion 2023-01-05 2 sites Stand-alone
    Other conditions: Ovarian Cancer
    View official trial listing →
  • Completed NCT NCT03416127

    Effect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes Mellitus

    Not yet reported University of Guadalajara 36 participants Est. completion 2019-12-20 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03419624

    The Potential of Dapagliflozin Plus Exenatide in Obese Insulin-resistant Patients

    Not yet reported Universitätsklinikum Hamburg-Eppendorf 13 participants Est. completion 2019-08-05 4 sites Added to GLP-1
    Type 2 diabetes Other conditions: Obesity
    View official trial listing →
  • Status unknown NCT NCT03421119

    Comparing Efficacy and Safety of CinnaGen-liraglutide Versus Victoza® in Patients With Type II Diabetes

    Not yet reported Cinnagen 300 participants Est. completion 2019-12-01
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03429543

    Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

    Not yet reported Boehringer Ingelheim 175 participants Est. completion 2023-05-31 83 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03430856

    Comparison of Insulin Tregopil (IN-105) With Insulin Aspart in Type 2 Diabetes Mellitus Patients

    Not yet reported, Not yet reported Biocon Limited 143 participants Est. completion 2019-02-20 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03441750

    Efficacy of Metformin in Preventing Diabetes in China

    Not yet reported Chinese Association of Geriatric Research 1724 participants Est. completion 2021-06-30 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Terminated NCT NCT03451006

    Effect of Metformin on Frailty in 12 Subjects

    Not yet reported Mayo Clinic 7 participants Est. completion 2021-12-16 1 site
    Other conditions: Aging, Inflammation, Frailty
    View official trial listing →
  • Completed NCT NCT03451734

    Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients

    Central South University 2000 participants Est. completion 2021-06-30 1 site
    Metabolic syndrome Other conditions: Schizophrenia
    View official trial listing →
  • Completed NCT NCT03458208

    Bioequivalence Study of Metformin 1000 mg Tablets Immediate Release (IR) Versus Glucophage® 1000 mg Tablets IR In Healthy Subjects

    Not yet reported Geropharm 18 participants Est. completion 2017-03-02 1 site Stand-alone
    Other conditions: Bioequivalence
    View official trial listing →
  • Terminated NCT NCT03477162

    Metformin Pharmacology in Human Cancers: A Proof of Principle Study

    Not yet reported Dartmouth-Hitchcock Medical Center 18 participants Est. completion 2021-11-30 1 site Stand-alone
    Other conditions: Thoracic Neoplasm
    View official trial listing →
  • Completed NCT NCT03479476

    A Trial of Metformin in Individuals With Fragile X Syndrome

    Not yet reported, Not yet reported University of California, Davis 120 participants Est. completion 2024-05-22 3 sites
    Other conditions: Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome Disorders
    View official trial listing →
  • Completed NCT NCT03503942

    The Pre-Diabetes Interventions and Continued Tracking to Ease-out Diabetes (Pre-DICTED) Program

    Not yet reported Singapore General Hospital 751 participants Est. completion 2024-04-15 1 site
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT03507413

    Metformin Therapy in Non-diabetic AAA Patients

    Not yet reported, Not yet reported Medical University of Vienna 170 participants Est. completion 2024-05-01 1 site
    Other conditions: Abdominal Aortic Aneurysm
    View official trial listing →
  • Status unknown NCT NCT03513874

    Metformin Plus Insulin on Non-obese Autoimmune Diabetes

    Not yet reported Second Xiangya Hospital of Central South University 15 participants Est. completion 2021-04-01 1 site Stand-alone
    Other conditions: Type 1 Diabetes Mellitus, Autoimmune Diabetes
    View official trial listing →
  • Status unknown NCT NCT03525028

    A Clinical Trial of Metformin to Decrease Glucocorticoids Side Effects in Patients With Autoimmune Uveitis

    Not yet reported Tianjin Medical University 138 participants Est. completion 2023-01-01 1 site Stand-alone
    Other conditions: Uveitis, Metformin, Glucocorticoid
    View official trial listing →
  • Status unknown NCT NCT03538704

    Effect of Fertility-sparing Therapy of Early Endometrial Cancer

    Not yet reported Peking University People's Hospital 80 participants Est. completion 2020-12-31 1 site Stand-alone
    Other conditions: Endometrial Cancer, Fertility
    View official trial listing →
  • Completed NCT NCT03555565

    Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"

    Takeda 1026 participants Est. completion 2019-10-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03558867

    Personalised Medicine in Pre-diabetes and Early Type 2 Diabetes

    Not yet reported Garvan Institute of Medical Research 138 participants Est. completion 2024-07-23 1 site
    Type 2 diabetes Other conditions: Pre Diabetes
    View official trial listing →
  • Completed NCT NCT03566810

    Glucophage Extended Release (GXR) China Bioequivalence Study (Nantong - Darmstadt)

    Not yet reported Merck KGaA, Darmstadt, Germany 54 participants Est. completion 2018-11-28 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03583385

    Glucophage® Extended Release (XR) 750 Milligram (mg) Indonesia Bioequivalence (BE) Study

    Not yet reported Merck KGaA, Darmstadt, Germany 48 participants Est. completion 2018-10-05 1 site
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT03585777

    Compare Serum Klotho Levels in Patients on Oral Antidiabetic Treatment

    Fayoum University 90 participants Est. completion 2019-03 1 site
    Other conditions: Compare Serum Level of Klotho in Patients on Oral Antidiabetic Treatment
    View official trial listing →
  • Status unknown NCT NCT03590262

    Effect of Metformin as add-on Therapy on Glycemic Control and Other Outcomes in Type 1 Diabetes

    Not yet reported Shenzhen People's Hospital 20 participants Est. completion 2019-09-30 1 site Stand-alone
    Other conditions: Type 1 Diabetes Mellitus, Metformin
    View official trial listing →
  • Completed NCT NCT03593135

    Effect of Apple Cider Vinegar in Type 2 Diabetics

    Not yet reported Sheikh Zayed Federal Postgraduate Medical Institute 126 participants Est. completion 2017-11-14 1 site Stand-alone
    Other conditions: Randomized Controlled Trial, Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03596450

    Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial

    Not yet reported Novo Nordisk A/S 1278 participants Est. completion 2023-06-09 122 sites
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT03603912

    Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)

    Not yet reported Mina Chung, MD 175 participants Est. completion 2026-12 1 site
    Other conditions: Atrial Fibrillation
    View official trial listing →
  • Completed NCT NCT03618654

    Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 38 participants Est. completion 2022-12-07 1 site Stand-alone
    Other conditions: Head and Neck Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT03629054

    This Study in Healthy People Tests Whether Taking a Low Strength of Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills

    Not yet reported Boehringer Ingelheim 30 participants Est. completion 2018-11-05 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT03639545

    The Effects of Empagliflozin on Arterial Wall Characteristics

    Not yet reported University Medical Centre Ljubljana 120 participants Est. completion 2019-01-30 1 site
    Other conditions: Vascular Stiffness, Hypoglycemic Agents, Diabetes Complications, Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT03651895

    Metformin to Reduce Airway Glucose in COPD Patients

    Not yet reported Imperial College London 14 participants Est. completion 2023-06-01 1 site
    Other conditions: Chronic Obstructive Pulmonary Disease
    View official trial listing →
  • Terminated NCT NCT03684642

    Efficacy and Safety of Efpeglenatide Versus Dulaglutide in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin

    Not yet reported Sanofi 908 participants Est. completion 2020-11-17 45 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03685357

    Correlation Between Idiopathic Parkinson's Disease and Diabetes Mellitus

    Ain Shams University 120 participants Est. completion 2020-01 1 site
    Other conditions: Observation
    View official trial listing →
  • Status unknown NCT NCT03685409

    Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions

    Not yet reported Cairo University 62 participants Est. completion 2020-09-30 1 site
    Other conditions: Oral Cancer
    View official trial listing →
  • Status unknown NCT NCT03709147

    Metformin Plus/Minus Fasting Mimicking Diet to Target the Metabolic Vulnerabilities of LKB1-inactive Lung Adenocarcinoma

    Not yet reported Marina Garassino 64 participants Est. completion 2023-09-10 1 site Stand-alone
    Other conditions: Advanced LKB1-inactive Lung Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT03711682

    Reducing Plasma Glucose Effect of Cinnamon in Type 2 Diabetic Patients in the Municipality of Comasagua

    Not yet reported, Not yet reported Universidad Dr. José Matías Delgado 30 participants Est. completion 2018-05-23 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03713801

    Impact of Metformin on Immunity

    Not yet reported The University of Texas Health Science Center at San Antonio 18 participants Est. completion 2024-07-16 1 site
    Other conditions: Aging, Vaccine Response Impaired
    View official trial listing →
  • Completed NCT NCT03714594

    Effects of Dapagliflozin+Saxagliptin in Addition to Metformin v/s Saxagliptin or Dapagliflozin in Patients With DM2.

    Not yet reported University of Pisa 48 participants Est. completion 2022-08-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03717194

    Effect of Ertugliflozin on Cardiac Function in Diabetes

    Not yet reported Soo Lim 102 participants Est. completion 2023-04-30 1 site Stand-alone
    Type 2 diabetesHeart failure
    View official trial listing →
  • Completed NCT NCT03733132

    Metformin Effect on Brain Function in Insulin Resistant Elderly People

    Not yet reported Mayo Clinic 40 participants Est. completion 2023-04-05 1 site
    Other conditions: Insulin Resistance, Obesity, Obesity, Abdominal
    View official trial listing →
  • Completed NCT NCT03748810

    Head-to-head Comparison of Empagliflozin and Dapagliflozin

    Chungbuk National University Hospital 600 participants Est. completion 2022-06-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03756623

    Effect of Metformin and Probiotics on Gut Microbiome in Healthy Subjects

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 90 participants Est. completion 2019-06-30 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03765359

    Metformin Use to Improve Pregnancy Outcome in Women With Type 1 Diabetes.

    Not yet reported Tampere University Hospital 101 participants Est. completion 2022-12-19 5 sites
    Other conditions: Diabetic Pregnancy, Insulin Resistance, Type1diabetes
    View official trial listing →
  • Completed NCT NCT03766256

    Shared Decision Making in Diabetes Prevention for Women With a History of GDM

    Not yet reported University of California, Los Angeles 33 participants Est. completion 2019-12-28 20 sites Stand-alone
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT03766308

    The Clinical Study of the Effect of Highland Barley Diet on Blood Glucose in Patients With Type 2 Diabetes Mellitus

    Not yet reported Xuefeng Yu 40 participants Est. completion 2020-12-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03770728

    Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Alone or in Combination With Sulfonylurea

    Not yet reported Sanofi 312 participants Est. completion 2020-12-27 48 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03772262

    Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach

    Not yet reported Washington State University 16 participants Est. completion 2019-03-31 1 site Stand-alone
    Other conditions: Interaction Drug Food
    View official trial listing →
  • Completed NCT NCT03772964

    Effects of Metformin in a Non-Diabetic Patient Population

    Not yet reported, Not yet reported Brian Zuckerbraun 32 participants Est. completion 2020-03-31 1 site
    Other conditions: Inflammatory Response
    View official trial listing →
  • Status unknown NCT NCT03774108

    Metformin and Systemic Inflammation in HIV

    Not yet reported Hospital Civil de Guadalajara 40 participants Est. completion 2020-01-08 1 site Stand-alone
    Prediabetes Other conditions: HIV-1-infection
    View official trial listing →
  • Completed NCT NCT03787017

    A Study to Compare MP-513 20mg & Metformin XR 1000mg FDC With Coadministration of the Two Separate Drugs

    Not yet reported Handok Inc. 36 participants Est. completion 2014-09 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT03787043

    A Study to Evaluate the Effect of Food on Fixed-Dose Combination of MP-513 10 mg and Metformin XR 750 mg

    Not yet reported Handok Inc. 30 participants Est. completion 2014-06 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT03800602

    Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

    Not yet reported Emory University 29 participants Est. completion 2021-09-04 3 sites Stand-alone
    Obstructive sleep apnea Other conditions: Colorectal Adenocarcinoma, Refractory Colorectal Carcinoma, Stage IV Colorectal Cancer, Stage IVA Colorectal Cancer, Stage IVB Colorectal Cancer, Stage IVC Colorectal Cancer, Colorectal Cancer Metastatic
    View official trial listing →
  • Withdrawn NCT NCT03813316

    Approaches To Therapy Escalation In T2D

    Not yet reported LMC Diabetes & Endocrinology Ltd. Est. completion 2019-09-18 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03824002

    Dulaglutide in Diabetic Patients, Relationship Between Arterial Stiffness, Endothelial Function, Clinical and Laboratory Variables

    Not yet reported University of Palermo 92 participants Est. completion 2018-04-20 1 site Added to GLP-1
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT03833466

    Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo)

    Not yet reported Peking University 15 participants Est. completion 2020-06-20 1 site Stand-alone
    Other conditions: Esophageal Squamous Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT03842267

    A Study to Evaluate the Efficacy and Safety of Gemigliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Dapagliflozin and Metformin (SOLUTION Study)

    Not yet reported LG Chem 315 participants Est. completion 2022-11-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03851432

    Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin

    Not yet reported Sihuan Pharmaceutical Holdings Group Ltd. 390 participants Est. completion 2021-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03862963

    Lifestyle Intervention to Treat Diabetes in the Marshall Islands

    Not yet reported University of Alabama at Birmingham 138 participants Est. completion 2008-07-31
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03871621

    Left Ventricular Functional Changes of Uncontrolled Diabetes by Dapagliflozin Treatment Trial

    Not yet reported Mackay Memorial Hospital 76 participants Est. completion 2022-08-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03898037

    Effect of Lifestyle and/or Metformin Intervention on Pregnancy Outcome, A Pilot Randomized Controlled Trial

    Not yet reported Reproductive & Genetic Hospital of CITIC-Xiangya 80 participants Est. completion 2021-06-30 1 site Stand-alone
    Other conditions: Infertility, Female, Obesity, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT03916263

    Low Starch Dietary Education Program vs. Traditional Treatment for PCOS

    Not yet reported Texas Tech University Health Sciences Center 71 participants Est. completion 2022-12-31 1 site
    Other conditions: PCOS, Diet Modification, Metabolism, Nutrition Disorders
    View official trial listing →
  • Completed NCT NCT03921242

    Comparative Effectiveness of Metformin for Type 2 Diabetes With Chronic Kidney Disease

    Weill Medical College of Cornell University 4888 participants Est. completion 2023-08-01 2 sites
    Type 2 diabetes Other conditions: Renal Insufficiency, Chronic
    View official trial listing →
  • Completed NCT NCT03945656

    A Research Study of How Overdosing of a New Once Weekly Medicine NNC0148-0287 C (Insulin 287) Influences the Blood Sugar Level in People With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 43 participants Est. completion 2021-09-27 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03950505

    To Evaluate the Effect of Nesinaact on Non-alcoholic Steatohepatitis Through MRI and Liver Fibroscan in Patients With Type 2 Diabetes

    Not yet reported Yonsei University 60 participants Est. completion 2020-12 1 site
    Type 2 diabetes Other conditions: Non-alcoholic Steatohepatitis
    View official trial listing →
  • Completed NCT NCT03956290

    Time Restricted EATing (TREAT) Pilot Study

    Not yet reported Columbia University 64 participants Est. completion 2021-01-11 1 site
    Other conditions: Overweight and Obesity, Pre Diabetes
    View official trial listing →
  • Completed NCT NCT03967496

    Assessment of Immediate Postoperative Delirium (IPD) in Adult Patients: Incidence and Etiologic Factors

    Sultan Qaboos University 402 participants Est. completion 2019-03-31 1 site
    Other conditions: Delirium, Anesthesia; Adverse Effect
    View official trial listing →
  • Completed NCT NCT03969719

    A Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus

    Not yet reported Pfizer 164 participants Est. completion 2021-03-30 106 sites
    Other conditions: Non-alcoholic Steatohepatitis
    View official trial listing →
  • Status unknown NCT NCT03994744

    Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLC

    Not yet reported Hunan Cancer Hospital 68 participants Est. completion 2022-07-01 1 site Stand-alone
    Other conditions: Small-cell Lung Cancer, Small Cell Lung Carcinoma, Small Cell Lung Cancer Recurrent, Small Cell Lung Cancer Extensive Stage
    View official trial listing →
  • Completed NCT NCT04009603

    Comparison of Probiotics, Metformin & Their Combination Therapy in the Treatment of PCOS

    Not yet reported Ziauddin University 78 participants Est. completion 2020-01-28 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT04029272

    Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients

    Not yet reported Peking Union Medical College Hospital 80 participants Est. completion 2020-12-31 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04029480

    Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

    Not yet reported Merck Sharp & Dohme LLC 166 participants Est. completion 2025-04-11 104 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04033107

    High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors

    Not yet reported Zhongnan Hospital 30 participants Est. completion 2024-12 1 site
    Other conditions: Hepatocellular Cancer, Pancreatic Cancer, Gastric Cancer, Colorectal Cancer
    View official trial listing →
  • Completed NCT NCT04043221

    Long Term Metformin in Women With Polycystic Ovary Syndrome

    University Medical Centre Ljubljana 180 participants Est. completion 2019-01-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04075110

    Investigation the Safety and Efficacy of The Antileukotriene Agents, Montelukast, as Adjuvant Therapy in Obese Patients With Type 2 Diabetes Mellitus

    Not yet reported Sadat City University 100 participants Est. completion 2023-04-10 1 site Stand-alone
    Other conditions: Obesity; Endocrine; Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT04081857

    A Study to Evaluate the Pharmacokinetics and Safety of HCP1704 in Healthy Subjects

    Not yet reported Hanmi Pharmaceutical Company Limited 48 participants Est. completion 2019-08-05 1 site Stand-alone
    Other conditions: Health, Subjective
    View official trial listing →
  • Status unknown NCT NCT04089813

    Effect of Metformin on Chronic Pain After Thoracic Surgery in Diabetic Patients

    Xuzhou Medical University 200 participants Est. completion 2020-12-31 1 site
    Other conditions: Postoperative Chronic Pain
    View official trial listing →
  • Completed NCT NCT04120259

    Effect of Apple Cider Vinegar and Metformin Combination vs Metformin Alone in Type 2 Diabetics

    Not yet reported Ziauddin University 126 participants Est. completion 2019-08-26 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04131582

    Effect of Empagliflozin + Linagliptin + Metformin + Lifestyle in Patients With Prediabetes

    Not yet reported Universidad de Guanajuato 34 participants Est. completion 2020-12-30 1 site Stand-alone
    Other conditions: Prediabetic State, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT04134650

    Effect of Low Dose Combination of Linagliptin + Metformin to Prevent Diabetes

    Not yet reported Universidad de Guanajuato 34 participants Est. completion 2020-07-01 1 site Stand-alone
    Other conditions: Prediabetic State, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT04141163

    Metformin in Patients With Fragile X

    Not yet reported, Not yet reported Rowan University 40 participants Est. completion 2021-03 1 site
    Other conditions: Fragile X Syndrome
    View official trial listing →
  • Completed NCT NCT04183868

    Effects of empagliFlozin on myocardIal metabOlic Rate of glucosE Estimated Through 18FDG PET (FIORE Study)

    Not yet reported University of Catanzaro 26 participants Est. completion 2021-10 1 site Stand-alone
    Type 2 diabetes Other conditions: Cardiovascular Risk Factor
    View official trial listing →
  • Status unknown NCT NCT04195243

    Dapagliflozin vs Empagliflozin on Flow Mediated Dilation in Type 2 Diabetes Mellitus

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2020-12-30 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04231435

    Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and Metformin

    Not yet reported Celgene 24 participants Est. completion 2020-02-21 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT04248998

    Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer

    Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 30 participants Est. completion 2024-05-01 1 site Stand-alone
    Other conditions: Triple-negative Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT04255238

    A Study to Evaluate the Efficacy and Safety of Dual add-on Therapy With Gemigliptin 50 mg and Dapagliflozin 10 mg Added to Metformin Who Have Inadequate Glycemic Control on Metformin Alone

    Not yet reported LG Chem 468 participants Est. completion 2022-12-30
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04268563

    Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients

    Not yet reported, Not yet reported Shahid Beheshti University of Medical Sciences 80 participants Est. completion 2021-07-30 1 site
    Other conditions: Polycystic Ovary Syndrome, Infertility, ART
    View official trial listing →
  • Completed NCT NCT04271189

    Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs

    Not yet reported Azienda Ospedaliero-Universitaria di Parma 108 participants Est. completion 2024-12-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04283318

    Prolonged Fasting on Glucose Metabolism and Hormonal Regulation in Healthy, Obese and Subjects With Type 2 Diabetes

    Not yet reported Medical University of Graz 80 participants Est. completion 2022-02-28 1 site
    Type 2 diabetes Other conditions: Healthy, Obesity, Type 1 Diabetes
    View official trial listing →
  • Status unknown NCT NCT04287387

    Response of Gut Microbiota in Type 2 Diabetes to Hypoglycemic Agents

    Not yet reported Peking Union Medical College Hospital 180 participants Est. completion 2021-03-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04288778

    A Study to Assess Safety of Canagliflozin and Metformin Hydrochloride Combination Given as a Supplement to Diet and Exercise to Improve Blood Sugar Level in Indian Adult Participants With Diabetes

    Not yet reported Johnson & Johnson Private Limited 276 participants Est. completion 2022-07-26 10 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT04298684

    Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules in Type 2 Diabetes

    Not yet reported Centre Hospitalier Universitaire de la Guadeloupe 90 participants Est. completion 2024-07-01 4 sites Stand-alone
    Type 2 diabetes Other conditions: Thyroid Nodule (Benign)
    View official trial listing →
  • Completed NCT NCT04335526

    A Clinical Study to Assess the Effect of Change of Bile Acid on the PD and Safety of Metformin and Microbiome Profiles

    Not yet reported Seoul National University Hospital 15 participants Est. completion 2020-10-21 1 site
    Other conditions: Human Microbiome
    View official trial listing →
  • Active, not recruiting NCT NCT04341571

    Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes.

    Not yet reported University of Guadalajara 30 participants Est. completion 2026-12 1 site
    Prediabetes Other conditions: Hyperglycemia, Resistance, Insulin
    View official trial listing →
  • Status unknown NCT NCT04390295

    Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 450 participants Est. completion 2020-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04392284

    Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics

    Not yet reported University of Alabama at Birmingham 40 participants Est. completion 2022-06-03 1 site Stand-alone
    Metabolic syndrome Other conditions: Insulin Resistance, Obesity, Diabetes, Hypertension, Dyslipidemias
    View official trial listing →
  • Active, not recruiting NCT NCT04407650

    Ursodeoxycholic Acid vs Metformin in Gestational Diabetes Mellitus

    Not yet reported King's College London 64 participants Est. completion 2025-05-31 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Status unknown NCT NCT04412746

    Covid-19 and Diabetes in West of Algeria

    Laboratoire De Recherche Sur Le Diabete, Université de Tlemcen 100 participants Est. completion 2020-06-30 1 site
    Other conditions: Coronavirus Infections, Diabetes Mellitus, Prevalence, Risk Factors, Patient Outcome Assessment, Severe Acute Respiratory Syndrome
    View official trial listing →
  • Completed NCT NCT04465877

    Study to Evaluate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of JTT-662 in Subjects With Type 2 Diabetes

    Not yet reported Akros Pharma Inc. 37 participants Est. completion 2021-02-17 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04477590

    Interactions of Medicine and Exercise With Meal Timing

    Not yet reported University of Castilla-La Mancha 160 participants Est. completion 2024-12-30 1 site
    Metabolic syndrome Other conditions: Exercise Training, Metformin, Statins, Angiotensin-Converting-Enzyme Inhibitor, Fasting, Intermittent, Angiotensin Hypertension
    View official trial listing →
  • Completed NCT NCT04497792

    Safety and Efficacy of Empagliflozin for Patients With Diabetes Mellitus and Planned Percutaneous Coronary Interventions

    Not yet reported Research Institute for Complex Problems of Cardiovascular Diseases, Russia 40 participants Est. completion 2019-11
    Cardiovascular disease Other conditions: Diabetes Mellitus, Percutaneous Coronary Intervention
    View official trial listing →
  • Status unknown NCT NCT04508634

    Treating Obese PCOS Patients With LSG vs. Met

    Not yet reported Shanghai 10th People's Hospital 90 participants Est. completion 2024-09-30 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04521049

    Tubular Markers in Response to Saxagliptin Therapy

    Not yet reported Beni-Suef University 80 participants Est. completion 2020-04-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04536805

    Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin

    Not yet reported, Not yet reported Institut Cancerologie de l'Ouest 44 participants Est. completion 2031-11 12 sites Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT04545736

    Oral Metformin for Treatment of ABCA4 Retinopathy

    Not yet reported, Not yet reported National Eye Institute (NEI) 55 participants Est. completion 2029-02-02 2 sites Stand-alone
    Other conditions: ABCA4 Retinopathy, Stargardt Disease, Retinal Dystrophy, Retinal Degeneration
    View official trial listing →
  • Status unknown NCT NCT04559308

    The Effect of Metformin on Breast Cancer Patients

    Not yet reported Beni-Suef University 80 participants Est. completion 2020-10 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT04576104

    Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

    Not yet reported Northwestern University 51 participants Est. completion 2026-06-30 8 sites
    Other conditions: Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, Endometrial Carcinoma
    View official trial listing →
  • Completed NCT NCT04617275

    A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY

    Not yet reported Pfizer 151 participants Est. completion 2021-11-17 38 sites
    Other conditions: Diabetes, Obesity
    View official trial listing →
  • Completed NCT NCT04622111

    Safety and Pharmacokinetics Study of CPL207280 Compound in Healthy Volunteers.

    Not yet reported Celon Pharma SA 68 participants Est. completion 2021-05-05 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT04623567

    Efficacy Assessment of Chinese Herbal Medicine Jiangtang Tiaozhi Recipe Treating Participants With Glucose and Lipid Metabolism Disturbances

    Not yet reported, Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 96 participants Est. completion 2024-06-30 1 site
    Type 2 diabetes Other conditions: Dyslipidemias
    View official trial listing →
  • Status unknown NCT NCT04653779

    A Clinical Trial to Evaluate the Preference Regarding Convenience of Medication and Efficacy/Safety of SUGAMET®XR Tablet 5/1000mg

    Not yet reported Dong-A ST Co., Ltd. 54 participants Est. completion 2021-07 2 sites Stand-alone
    Type 2 diabetes Other conditions: Renal Disease, Diabetes Mellitus, Metabolic Disease, Endocrine System Diseases
    View official trial listing →
  • Completed NCT NCT04654676

    DPP4 Inhibitor on Glycemic Variability

    Not yet reported University Malaysia Sarawak 12 participants Est. completion 2019-08-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT04662164

    A Study to Access the Efficacy in Type 2 Diabetes Mellitus on Stable Metformin

    Not yet reported, Not yet reported Shanghai HEP Pharmaceutical Co., Ltd. Est. completion 2025-12
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04667143

    Dual Add-on Therapy in Type 2 Diabetes Poorly Controlled With Metformin Monotherapy

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 760 participants Est. completion 2022-10
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Status unknown NCT NCT04672031

    Glycemic Targets for Pregnant Women With GDM and T2DM

    Not yet reported University of Southern California 120 participants Est. completion 2023-07 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabetes Mellitus in Pregnancy, Diabetes, Gestational
    View official trial listing →
  • Completed NCT NCT04706377

    Vitamin B12 Supplementation in Diabetic Neuropathy

    Not yet reported Aristotle University Of Thessaloniki 90 participants Est. completion 2020-02-28 1 site
    Other conditions: Diabetes Mellitus, Diabetic Neuropathies, Diabetic Complication, Diabetic Foot
    View official trial listing →
  • Withdrawn NCT NCT04741204

    Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer

    Not yet reported Woman's Est. completion 2022-09 1 site
    Other conditions: Breast Cancer Stage, Insulin Resistance, Racial Bias
    View official trial listing →
  • Terminated NCT NCT04754334

    A Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Oramed, Ltd. 346 participants Est. completion 2023-01-13 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04762966

    Study of Metformin Overdose

    Central Hospital, Nancy, France 50 participants Est. completion 2021-09-01 1 site
    Other conditions: Metformin Associated Lactic Acidosis
    View official trial listing →
  • Status unknown NCT NCT04799938

    Effect of Exercise on GDF-15 Levels in Prediabetic Patients

    Not yet reported Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey 70 participants Est. completion 2023-04-01 1 site
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT04817215

    Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus

    Not yet reported King Hamad University Hospital, Bahrain 608 participants Est. completion 2022-07 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT04836910

    Microbiome and Polycystic Ovaries

    Sheba Medical Center 40 participants Est. completion 2027-03-30 1 site
    Other conditions: Polycystic Ovary Syndrome, Microbial Colonization
    View official trial listing →
  • Completed NCT NCT04841668

    Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly

    Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta 50 participants Est. completion 2024-12-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04865835

    A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia.

    Not yet reported Otsuka Pharmaceutical Development & Commercialization, Inc. 21 participants Est. completion 2022-05-03 2 sites Stand-alone
    Other conditions: Schizophrenia
    View official trial listing →
  • Status unknown NCT NCT04882332

    Metformin Usage Index and Vitamin B12 Status in Egyptian Type 2 Diabetic Patients

    Cairo University 108 participants Est. completion 2022-10 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT04885712

    A Study to Evaluate the Efficacy and Safety of Pioglitazone 15mg or 30mg Add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin

    Not yet reported Boryung Pharmaceutical Co., Ltd 378 participants Est. completion 2023-03-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04902326

    Behavioral Economics and Self-Determination Theory to Change Diabetes Risk (BEST Change)

    Not yet reported University of Michigan 380 participants Est. completion 2023-09-18 1 site Stand-alone
    Other conditions: Pre Diabetes
    View official trial listing →
  • Completed NCT NCT04916093

    Safety and Efficacy of Antidiabetic Drugs in Recently Diagnosed Patients With Type 2 Diabetes

    Not yet reported Beni-Suef University 60 participants Est. completion 2020-12-15 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04931147

    A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers

    Not yet reported Redx Pharma Ltd 90 participants Est. completion 2023-03-08 1 site
    Other conditions: Fibrosis, Inflammation, Idiopathic Pulmonary Fibrosis, Non-alcoholic Steatohepatitis, Liver Diseases, Kidney Diseases
    View official trial listing →
  • Status unknown NCT NCT04984070

    Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety

    Not yet reported Fudan University 100 participants Est. completion 2024-12-31 1 site
    Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety
    View official trial listing →
  • Status unknown NCT NCT05025852

    The Effect of In-utero Exposure to Metformin in 5-11 Year Old Offspring of Mothers in the MiTy Trial

    Mount Sinai Hospital, Canada 220 participants Est. completion 2026-05 12 sites
    Type 2 diabetes Other conditions: Pregnancy in Diabetic, Child Obesity, Child Development
    View official trial listing →
  • Status unknown NCT NCT05032001

    ORAL ANTIDIABETICS EFFECT ON VISCERAL FAT

    Not yet reported Metabolic Research Unit 30 participants Est. completion 2022-08-01 1 site
    Type 2 diabetes Other conditions: Abdominal Obesity
    View official trial listing →
  • Completed NCT NCT05055219

    Conventional and Metabolomic Predictors of Prediabetes & Insulin Resistance

    University of Michigan 772 participants Est. completion 2020-02-19 1 site
    Prediabetes Other conditions: Obesity, Childhood
    View official trial listing →
  • Withdrawn NCT NCT05102071

    Clinical Outcomes and Healthcare Cost and Resource Utilization (HCRU) in Patients With Type 2 Diabetes and Cardiovascular Disease on 2nd Line Empagliflozin Versus 2nd Line Sulfonylureas

    Boehringer Ingelheim Est. completion 2022-06-15 1 site
    Type 2 diabetesCardiovascular disease
    View official trial listing →
  • Completed NCT NCT05124730

    Fasting Bioequivalence Study of 2 Metformin 500 mg Prolonged Release Tablets in 44 Healthy Male and Female Volunteers

    Not yet reported Joint Stock Company "Farmak" 44 participants Est. completion 2021-05-29 1 site Stand-alone
    Other conditions: Pharmacokinetics
    View official trial listing →
  • Completed NCT NCT05132023

    Bioequivalence Study of Empagliflozin & Metformin HCL From Empagliform 12.5/1000 mg F.C.T (Hikma Pharma, Egypt) and Synjardy 12.5/1000 mg F.C.T (Boehringer Ingelheim International GmbH, Germany)

    Not yet reported Genuine Research Center, Egypt 26 participants Est. completion 2019-05-15 1 site
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT05162690

    Efficacy of Dapagliflozin in Diabetes Associated Peripheral Neuropathy

    Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 40 participants Est. completion 2023-12-31 1 site
    Other conditions: Diabetic Peripheral Neuropathy
    View official trial listing →
  • Suspended NCT NCT05183204

    Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma

    Not yet reported Weill Medical College of Cornell University 33 participants Est. completion 2026-06 1 site Stand-alone
    Other conditions: Glioblastoma
    View official trial listing →
  • Status unknown NCT NCT05200793

    Efficacy of Empagliflozin or Linagliptin as an Alternative to Metformin for Treatment of Polycystic Ovary Syndrome

    Not yet reported Alexandria University 75 participants Est. completion 2022-09-01 1 site
    Other conditions: Polycystic Ovary Syndrome (PCOS)
    View official trial listing →
  • Status unknown NCT NCT05226897

    Clinical Trial to Assess the Efficacy and Safety of YYC405 in Type 2 Diabetes Patients

    Not yet reported Yooyoung Pharmaceutical Co., Ltd. 256 participants Est. completion 2023-06-26 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05232994

    Metformin and Esomeprazole For Preterm Pre-eclampsia

    Not yet reported Christiana Care Health Services 38 participants Est. completion 2025-12-31 1 site Stand-alone
    Other conditions: Preeclampsia Severe, Preeclampsia Second Trimester, Preterm Birth Complication
    View official trial listing →
  • Completed NCT NCT05233514

    Effect of Aerobic Exercise on Polycystic Ovary Syndrome

    Not yet reported Cairo University 40 participants Est. completion 2021-12-10 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT05280496

    A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes

    Not yet reported Tufts Medical Center 20 participants Est. completion 2025-04-18 1 site Stand-alone
    PrediabetesType 2 diabetes Other conditions: Diabetes, Gestational
    View official trial listing →
  • Status unknown NCT NCT05296044

    To Evaluate the Efficacy and Safety of JT-003 add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin

    Not yet reported Jeil Pharmaceutical Co., Ltd. 245 participants Est. completion 2024-02-28 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05305898

    "MetCool ACS"- Metformin "Cooling" Effect on Metformin-naive Patients Treated With PCI Because of Acute Coronary Syndrome

    Not yet reported Military Institute od Medicine National Research Institute 2000 participants Est. completion 2025-12 14 sites Stand-alone
    Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Status unknown NCT NCT05326490

    Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients With Poor Glycemic Control Via Metformin Hydrochloride Monotherapy

    Not yet reported PegBio Co., Ltd. 546 participants Est. completion 2024-10-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05326984

    Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia

    Not yet reported Hospital General de Mexico 20 participants Est. completion 2023-12 1 site
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT05329857

    The Study Intends to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safety Profile of Test Product Compared to Reference Product Will be Evaluated.

    Not yet reported AET Laboratories Private Limited 60 participants Est. completion 2016-03
    Other conditions: To Determine Bioequivalence Under Fed Conditions
    View official trial listing →
  • Completed NCT NCT05332795

    The Impact of Metformin on the Outcome of Gouty Arthritis in a Cohort of Egyptian Gouty Patients.

    Not yet reported Menoufia University 100 participants Est. completion 2024-02-20 1 site
    Other conditions: Gouty Arthritis
    View official trial listing →
  • Completed NCT NCT05343767

    Investigate the Efficacy and Safety of Low-Glu in Patients Newly Diagnosed With Type II Diabetes Mellitus

    Not yet reported Natural Wellness Egypt 198 participants Est. completion 2021-05-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05360147

    Liraglutide Improve Cognitive Function in Patients With Type 2 Diabetes Mellitus

    Not yet reported Third Military Medical University 30 participants Est. completion 2021-05-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05362799

    Different Induction Protocols in PCOS After Clomiphene Citrate Failed Pregnancy in Non-IVF Cycles

    Not yet reported Menoufia University 176 participants Est. completion 2023-12-31
    Other conditions: Infertility, Female
    View official trial listing →
  • Completed NCT NCT05363384

    A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 25 mg and MET XR 1,000 mg) in Healthy Volunteers

    Not yet reported Celltrion 48 participants Est. completion 2022-07-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05364164

    A Food Effect Study of CT-L01 After Oral Administration in Healthy Volunteers

    Not yet reported Celltrion 24 participants Est. completion 2022-07-25 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05365451

    Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters

    Not yet reported Washington State University 16 participants Est. completion 2023-07-22 1 site Stand-alone
    Other conditions: Interaction, Endogenous Biomarkers
    View official trial listing →
  • Active, not recruiting NCT NCT05366868

    Durable Effect of Imeglimin on the Glycemic Control in Patients With Type 2 Diabetes Mellitus

    Not yet reported National Center for Global Health and Medicine, Japan 567 participants Est. completion 2027-03-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05367063

    Canagliflozin and Myocardial Fibrosis

    Not yet reported Shanghai Zhongshan Hospital 45 participants Est. completion 2025-03-20 1 site
    Type 2 diabetes Other conditions: Cardiovascular Risk
    View official trial listing →
  • Completed NCT NCT05376969

    Evaluate the Long Term Safety and Efficacy of DWP16001 add-on to Metformin in Patients With T2DM Inadequately Controlled on Metformin

    Not yet reported Daewoong Pharmaceutical Co. LTD. 159 participants Est. completion 2022-05-16 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05400863

    Effect of NNS on Metformin/GDF15, Pilot

    Not yet reported University of Florida 46 participants Est. completion 2024-08-02 1 site
    Other conditions: Obesity, Adolescent, Pre Diabetes
    View official trial listing →
  • Completed NCT NCT05413369

    iGlarLixi vs IDegAsp in Chinese Participants After OAD(s)

    Not yet reported Sanofi 582 participants Est. completion 2023-10-20 60 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05416580

    Efficacy of Ursodeoxycholic Acid (UDCA) in Patients With Type 2 Diabetes

    Not yet reported University of Banja Luka 60 participants Est. completion 2024-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05429554

    The Effect of Metformin and DPP4 Inhibitors on Cognition and Cardiovascular Protection in Type 2 Diabetic Patients

    MTI University 60 participants Est. completion 2022-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05440591

    Effects of Dapagliflozin and Metformin on Vascular Function in Newly-Diagnosed Treatment-Naive Type 2 Diabetes

    Not yet reported Tan Tock Seng Hospital 150 participants Est. completion 2023-05-10 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT05451147

    A Comparative Study of the Effect of Ayurvedic Drugs and Metformin in the Management of Diabetes Mellitus (Type II)

    Not yet reported A & U Tibbia College Karol Bagh 48 participants Est. completion 2019-04-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05504226

    Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin 25 mg and Metformin

    Not yet reported Handok Inc. 214 participants Est. completion 2024-06-18 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05505994

    The Efficacy and Safety of DWP16001 in Combination With Metformin in T2DM Patients Inadequately Controlled on Metformin

    Not yet reported Daewoong Pharmaceutical Co. LTD. 340 participants Est. completion 2024-09 1 site
    Type 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease, Endocrine System Diseases
    View official trial listing →
  • Completed NCT NCT05521633

    Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty Liver

    Not yet reported King Edward Medical University 96 participants Est. completion 2022-05-24 1 site
    MASLD
    View official trial listing →
  • Terminated NCT NCT05536037

    Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions

    Not yet reported Thomas Jefferson University 4 participants Est. completion 2024-03-16 1 site Stand-alone
    Other conditions: Erythroplakia, Leukoplakia, Oral Cavity Carcinoma, Proliferative Verrucous Leukoplakia
    View official trial listing →
  • Status unknown NCT NCT05536193

    Topical Metformin Emulgel VS Salicylic Acid Peeling in Treatment of Acne Vulgaris

    Not yet reported Assiut University 34 participants Est. completion 2023-09-10 Stand-alone
    Other conditions: Acne Vulgaris
    View official trial listing →
  • Status unknown NCT NCT05545800

    Efficacy and Safety Of Different Regimens In Patients With Type 2 Diabetes Receiving Intensive Insulin Therapy

    Not yet reported Xiangya Hospital of Central South University 78 participants Est. completion 2024-06-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05549583

    Comparative Bioavailability Study of Sitagliptin/Metformin 50 mg/1000 mg Tablets in Healthy Male and Female Volunteers

    Not yet reported Galenicum Health 26 participants Est. completion 2018-04-25 1 site Stand-alone
    Type 2 diabetes Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT05550129

    Study to Evaluate the Drug-drug Interactions Between Metformin and AMG 510 in Healthy Participants

    Not yet reported Amgen 13 participants Est. completion 2019-11-25 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT05580523

    Aspirin Versus Metformin in Pregnancies at High Risk of Preterm Preeclampsia: a 3-arm Randomized Controlled Trial

    Not yet reported Chinese University of Hong Kong 3000 participants Est. completion 2025-11-30 6 sites Stand-alone
    Other conditions: Preeclampsia
    View official trial listing →
  • Completed NCT NCT05615467

    A Study of Effect of LY3556050 on Metformin in Healthy Participants

    Not yet reported Eli Lilly and Company 18 participants Est. completion 2022-12-27 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05638893

    Metformin as Adjuvant Therapy in Obese Knee Osteoarthritis Patients

    Not yet reported, Not yet reported Tanta University 50 participants Est. completion 2022-04-15 1 site
    Osteoarthritis
    View official trial listing →
  • Status unknown NCT NCT05663736

    Effect of Gemigliptin Versus Glimepiride on Cardiac Diastolic Function in Patients With Type 2 Diabetes

    Not yet reported Seoul National University Bundang Hospital 80 participants Est. completion 2023-12-31 1 site
    Other conditions: Ejection Fraction
    View official trial listing →
  • Completed NCT NCT05694221

    Drug Drug Interaction (DDI) Between Supaglutide and Digoxin or Metformin

    Not yet reported Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. 34 participants Est. completion 2023-08-17 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT05703984

    A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fasting Conditions

    Not yet reported GC Biopharma Corp 50 participants Est. completion 2023-04-19 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT05729386

    A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fed Conditions

    Not yet reported GC Biopharma Corp 34 participants Est. completion 2023-04-17 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT05741372

    A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver Cirrhosis

    Not yet reported Boehringer Ingelheim 28 participants Est. completion 2024-12-30 1 site
    Other conditions: Liver Cirrhosis
    View official trial listing →
  • Active, not recruiting NCT NCT05743387

    Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural Lesotho

    Not yet reported University Hospital, Basel, Switzerland 252 participants Est. completion 2027-12-31 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05753371

    Bioequivalence Study of Metformin Hydrochloride 500 mg Film-Coated Tablets in Indonesia Healthy Subject

    Not yet reported PT. Pyridam Farma Tbk 24 participants Est. completion 2022-03-31 1 site
    Other conditions: Drug Use
    View official trial listing →
  • Completed NCT NCT05801627

    SAL067 Treatment in Patients With Type 2 Diabetes Who Are Not Controlled by Metformin

    Not yet reported Shenzhen Salubris Pharmaceuticals Co., Ltd. 408 participants Est. completion 2022-05-24 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05815680

    A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese Subjects

    Not yet reported Innovent Biologics (Suzhou) Co. Ltd. 48 participants Est. completion 2023-10-30 1 site Stand-alone
    Other conditions: Overweight Subjects, Obese Subjects
    View official trial listing →
  • Withdrawn NCT NCT05828303

    A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors

    Not yet reported Turning Point Therapeutics, Inc. Est. completion 2025-11-30 33 sites Stand-alone
    Other conditions: Advanced Solid Tumor, Metastatic Solid Tumor
    View official trial listing →
  • Completed NCT NCT05838573

    Metformin Treatment on Cognitive Impairment of Schizophrenia

    Not yet reported Central South University 120 participants Est. completion 2026-06-08 4 sites
    Other conditions: Schizophrenia
    View official trial listing →
  • Withdrawn NCT NCT05854966

    CPI-613 Given With Metformin in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)

    Not yet reported Wake Forest University Health Sciences Est. completion 2025-09
    Other conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory, Granulocytic Sarcoma
    View official trial listing →
  • Completed NCT NCT05874180

    A Pharmacokinetic Study of DW6013 (FDC of Linagliptin and Metformin) in Healthy Adult Volunteers in Fed Condition

    Not yet reported Dong Wha Pharmaceutical Co. Ltd. 31 participants Est. completion 2023-02-03 1 site
    Other conditions: Healthy Subjects
    View official trial listing →
  • Status unknown NCT NCT05878535

    METFORMIN FOR ATRIAL FIBRILLATION

    Not yet reported Arab Contractors Medical Centre 770 participants Est. completion 2025-04 1 site
    Other conditions: Atrial Fibrillation
    View official trial listing →
  • Completed NCT NCT05900284

    Safety and Feasibility of Metformin for Sepsis Induced AKI

    Not yet reported Hernando Gomez 80 participants Est. completion 2026-05-18 1 site
    Other conditions: Sepsis, Septic Shock, Acute Kidney Injury, Metformin
    View official trial listing →
  • Completed NCT NCT05921942

    The Impact of Metformin Administration on the Clinical Outcome of Stage IV Colon Cancer

    Not yet reported Ain Shams University 70 participants Est. completion 2022-12-30 1 site
    Other conditions: Colorectal Cancer
    View official trial listing →
  • Status unknown NCT NCT05942963

    Efficacy of Empagliflozin and Pioglitazone in Diabetic Patients With NAFLD

    Not yet reported Jinnah Postgraduate Medical Centre 240 participants Est. completion 2024-04 1 site Stand-alone
    Other conditions: Non-Alcoholic Fatty Liver Disease, Type2diabetes
    View official trial listing →
  • Status unknown NCT NCT05950516

    Efficacy and Safety of Semaglutide Ingection in Subjects With Type 2 Diabetes

    Not yet reported Qilu Pharmaceutical Co., Ltd. 478 participants Est. completion 2025-01-22 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05965908

    Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome

    Not yet reported Beni-Suef University 183 participants Est. completion 2025-12-30 1 site
    Other conditions: Polycystic Ovary
    View official trial listing →
  • Active, not recruiting NCT NCT06005142

    Therapeutic Intervention of Eriomin Associated with Metformin in the Control of Hyperglycemia in Pre-Diabetic Patients

    Not yet reported Thais Cesar 80 participants Est. completion 2024-12-30 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT06015594

    Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.

    Not yet reported University of Cagliari 168 participants Est. completion 2022-05-01 Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT06031168

    1% Metformin Gel-coated Implants and Osteointegration and Crestal Marginal Bone Loss

    Not yet reported Hams Hamed Abdelrahman 26 participants Est. completion 2023-11-30 1 site
    Other conditions: Osteointegration
    View official trial listing →
  • Status unknown NCT NCT06041399

    The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy

    Not yet reported First Affiliated Hospital of Wenzhou Medical University 1400 participants Est. completion 2025-01-02 1 site
    Other conditions: Diabetic Peripheral Neuropathy
    View official trial listing →
  • Completed NCT NCT06045221

    A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin

    Not yet reported Eli Lilly and Company 1698 participants Est. completion 2025-08-22 131 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06059287

    The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics

    Not yet reported RenJi Hospital 64 participants Est. completion 2025-12-31
    Type 2 diabetes Other conditions: Obesity, Sodium-glucose Co-transporter-2 Inhibitor, Myocardial Fibrosis, Magnetic Resonance Imaging
    View official trial listing →
  • Status unknown NCT NCT06064552

    Screening For First Trimester's Hyperglycemia in High and Low Risk Pregnancy

    Sohag University 100 participants Est. completion 2024-09-24 1 site
    Other conditions: Screening for Hyperglycemia in First Trimester in High and Low Risk Pregnancy
    View official trial listing →
  • Completed NCT NCT06068686

    Vildagliptin Versus Glimepiride in Type 2 Diabetic Patients

    Not yet reported Damanhour University 70 participants Est. completion 2024-12-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06073600

    Bioequivalence Study to Compare Metformin / Vildagliptin Versus Galvumet®

    Not yet reported Reseach Laboratory of Clinical and Experimental Pharmacology 18 participants Est. completion 2022-11-13 1 site Stand-alone
    Other conditions: Fed Conditions
    View official trial listing →
  • Status unknown NCT NCT06080802

    The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction

    Not yet reported, Not yet reported October University for Modern Sciences and Arts 80 participants Est. completion 2024-12-01 1 site Stand-alone
    Heart failure Other conditions: Diabete Type 2
    View official trial listing →
  • Withdrawn NCT NCT06083675

    Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S Est. completion 2027-05-28 100 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06084156

    A Study to Evaluate the DDI of HSK7653 With Metformin

    Not yet reported Haisco Pharmaceutical Group Co., Ltd. 22 participants Est. completion 2019-12-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06101147

    Effect of Vitamin D Supplementation on Testosterone Level in Women With Polycystic Ovary Syndrome

    Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 66 participants Est. completion 2024-07-30 1 site
    Other conditions: PCOS, Vitamin D
    View official trial listing →
  • Completed NCT NCT06109311

    A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor

    Not yet reported Eli Lilly and Company 546 participants Est. completion 2025-09-15 70 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06125587

    Chiglitazar/Metformin in Non-obese Women With PCOS

    Not yet reported, Not yet reported Shengjing Hospital 55 participants Est. completion 2024-11-20 1 site
    Other conditions: Polycystic Ovary Syndrome, Chiglitazar, Metformin
    View official trial listing →
  • Status unknown NCT NCT06140485

    A Trial to Investigate the Efficacy and Safety of NW Low-Glu® in Patients With Type II Diabetes Mellitus

    Not yet reported Natural Wellness Egypt 400 participants Est. completion 2025-10
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06181422

    Metformin and Lactoferrin in Sepsis in Icu

    Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2024-06-09 1 site
    Other conditions: Sepsis
    View official trial listing →
  • Status unknown NCT NCT06182618

    Retrospective Analysis for Patients With Metabolic Syndrome

    Second Affiliated Hospital, Zhejiang University, School of Medicine 400 participants Est. completion 2024-01-01 1 site
    Metabolic syndrome
    View official trial listing →
  • Status unknown NCT NCT06188234

    The Prescription Patterns and Clinical Efficacy of Tenero Tab/Tenero M SR Tab

    Hanlim Pharm. Co., Ltd. 3000 participants Est. completion 2026-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06192108

    A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin

    Not yet reported Eli Lilly and Company 962 participants Est. completion 2025-09-26 74 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06199544

    Effect of Unani Medicine for the Management of Anomalies Associated With Polycystic Ovarian Syndrome

    Not yet reported Hamdard University 150 participants Est. completion 2024-12-01 1 site
    Other conditions: Comparative Study
    View official trial listing →
  • Completed NCT NCT06204107

    A Clinical Trial to Evaluate the Food Effect on Pharmacokinetic Profiles and Safety of CKD-379

    Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2023-12-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06217887

    Efficacy Comparison of Polyethylene Glycol Loxenatide and Gliclazide on the Brain Function in T2DM Patients

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 58 participants Est. completion 2024-06 1 site
    Type 2 diabetes Other conditions: Cognitive Function Abnormal
    View official trial listing →
  • Completed NCT NCT06221969

    A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor

    Not yet reported Novo Nordisk A/S 1024 participants Est. completion 2026-04-06 197 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06233201

    Sitagliptin and Metformin Hydrochloride Tablets 50 mg/500 mg Relative to Originator

    Not yet reported Bio-innova Co., Ltd 34 participants Est. completion 2024-07-28
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT06235086

    A Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes Mellitus

    Not yet reported CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. 632 participants Est. completion 2026-02-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06243536

    The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients

    Not yet reported University Hospital Sestre Milosrdnice 60 participants Est. completion 2024-12-31 1 site
    Type 2 diabetes Other conditions: Overweight, Disordered Eating Behaviors
    View official trial listing →
  • Completed NCT NCT06244550

    Clinical Trials Using HepatoKeeper Herbal Essentials to Treat Non-alcoholic Fatty Liver Disease and Metabolic Factors

    Not yet reported Taipei City Hospital 60 participants Est. completion 2023-06-13 1 site
    Other conditions: Non-alcoholic Fatty Liver Disease, Liver Fibrosis, Liver Injury
    View official trial listing →
  • Completed NCT NCT06247748

    Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects

    Not yet reported Beijing Dongfang Biotech Co., Ltd. 28 participants Est. completion 2024-04-15 1 site
    Type 2 diabetes Other conditions: Overweight
    View official trial listing →
  • Completed NCT NCT06280274

    Metformin Use in Patients Undergoing Total Joint Replacement Surgery

    Not yet reported Oregon Health and Science University 40 participants Est. completion 2025-09-15 1 site Stand-alone
    Other conditions: Hyperglycemia
    View official trial listing →
  • Terminated NCT NCT06296836

    Effect of Continuing Versus Holding Metformin During Hospitalizations.

    Not yet reported University of Illinois at Chicago 22 participants Est. completion 2026-04-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06323161

    A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without Metformin

    Not yet reported Novo Nordisk A/S 274 participants Est. completion 2025-10-23 61 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT06333080

    The Effect of Adherence to Oral Semaglutide on Glycaemic Control in People With Type 2 Diabetes Treated With Metformin

    Aalborg University Hospital 1 participants Est. completion 2025-07-29 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06335134

    A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin

    Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 57 participants Est. completion 2024-06-28 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT06357273

    The Effect of White Tea Consumption on Obesity

    Recep Tayyip Erdogan University 91 participants Est. completion 2023-12-15 1 site
    Other conditions: Obesity, Obesity; Endocrine, Obesity Adult Onset
    View official trial listing →
  • Status unknown NCT NCT06405971

    Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE)

    Not yet reported Ming Lv 60 participants Est. completion 2025-06-01 1 site
    Other conditions: Dissecting Aneurysm of Cerebral Artery
    View official trial listing →
  • Completed NCT NCT06416800

    A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants

    Not yet reported Incyte Corporation 71 participants Est. completion 2025-01-15 1 site Stand-alone
    Other conditions: Healthy Participants
    View official trial listing →
  • Status unknown NCT NCT06439758

    Effects of First-Line Oral Hypoglycemics in Bone Markers of Treatment Naïve Saudi Adults With Type 2 Diabetes

    Not yet reported King Saud University 111 participants Est. completion 2025-12-01
    Other conditions: Diabetes Type 2, Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT06449235

    Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh

    Not yet reported Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders 938 participants Est. completion 2025-06 1 site
    Other conditions: Type2diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06460896

    Analysis of the Influence of Gastric By-Pass on the Pharmacokinetics of Common Drugs

    Not yet reported Assistance Publique - Hôpitaux de Paris 64 participants Est. completion 2027-09 1 site
    Other conditions: Bypass Bariatric Surgery
    View official trial listing →
  • Completed NCT NCT06473662

    Study to Evaluate the Safety and Efficacy of Oral Insulin Formulation in Type 2 Diabetes Mellitus Subjects

    Not yet reported Roger New 153 participants Est. completion 2020-07-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06479434

    Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls

    Not yet reported Aga Khan University 110 participants Est. completion 2025-10-02 1 site
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT06492655

    To Evaluate the Food Effect on Pharmacokinetic Profiles and Safety in Healthy Volunteers

    Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2024-08-08
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06495931

    Study on Drug Interaction of HRS-1780 Tablets, Henagliflozin Tablets, Metformin Tablets and HRS-7535 Tablets in Healthy Human

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 24 participants Est. completion 2024-08-13 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06504862

    A Study in Healthy Men to Test Whether Zongertinib Influences the Amount of 4 Other Medicines (Dabigatran, Rosuvastatin, Metformin, and Furosemide) in the Blood

    Not yet reported Boehringer Ingelheim 32 participants Est. completion 2024-12-18 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT06515652

    To Compare the Effects of Herbal Medicines With Traditional Allopathic Medicines in Cases of Patients With Metabolic Syndrome

    Not yet reported Hamdard University 200 participants Est. completion 2024-08-30 1 site
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT06523595

    Evaluation of the Pharmacokinetic Drug-drug Interactions Between VX-993 and Metformin in Healthy Adults

    Not yet reported Vertex Pharmaceuticals Incorporated 31 participants Est. completion 2024-12-31 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Withdrawn NCT NCT06526494

    Metformin and Vascular Function in Prediabetes

    Not yet reported Diana Jalal Est. completion 2025-12-01 2 sites Stand-alone
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT06545994

    A Prospective Cohort Study on the Serum Kisspeptin Levels Throughout Pregnancy in PCOS

    Fudan University 180 participants Est. completion 2026-06-30 1 site
    Other conditions: Polycystic Ovary Syndrome, Pregnancy Complications
    View official trial listing →
  • Status unknown NCT NCT06559722

    A Trial Investigating the Efficacy and Safety of Insulin Degludec/Liraglutide Injection in Subjects With Type 2 Diabetes

    Not yet reported Tonghua Dongbao Pharmaceutical Co.,Ltd 510 participants Est. completion 2026-02
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06589141

    Comparison Between Metformin and Glyburide in the Management of Gestational Diabetes

    Not yet reported Assiut University 180 participants Est. completion 2026-06-30 Stand-alone
    Other conditions: Gestational Diabetes Mellitus in Pregnancy
    View official trial listing →
  • Completed NCT NCT06628544

    Trained Immunity in Fungal Infection and Its Mechanism

    Not yet reported Zhongnan Hospital 79 participants Est. completion 2023-12-01 1 site Stand-alone
    Other conditions: BCG Vaccination
    View official trial listing →
  • Not yet recruiting NCT NCT06682351

    Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention

    Not yet reported Stanford University 200 participants Est. completion 2027-12 1 site Stand-alone
    Type 2 diabetesPrediabetes
    View official trial listing →
  • Enrolling by invitation NCT NCT06683235

    Effect of Flaxseed as a Treatment for Adults With Type 2 Diabetes Mellitus in Mexico

    Not yet reported Universidad Autónoma Benito Juárez de Oaxaca 160 participants Est. completion 2025-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06688123

    Efficacy and Safety of SHR-3167 and Insulin Glargine in Type 2 Diabetes Subjects

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 275 participants Est. completion 2026-04-22 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06727838

    Study on Drug Interaction of Metformin Tablets and HRS-7535 Tablets in Healthy Human

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 18 participants Est. completion 2025-01-25 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT06728982

    Impact Of Metformin In Rectal Cancer Patients

    Not yet reported, Not yet reported Minia University 85 participants Est. completion 2025-07-15 2 sites
    Other conditions: Rectal Cancer Patients
    View official trial listing →
  • Not yet recruiting NCT NCT06743698

    META Trial - a Mixed Methods Process Evaluation

    University College Dublin 60 participants Est. completion 2027-02
    Prediabetes Other conditions: HIV
    View official trial listing →
  • Enrolling by invitation NCT NCT06773923

    Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration

    Not yet reported Universidad Austral de Chile 10 participants Est. completion 2025-12-01 1 site
    Other conditions: Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures, Bone Loss, Age Related
    View official trial listing →
  • Not yet recruiting NCT NCT06775093

    Effects of GLP-1RAs on Reproductive Outcomes in PCOS and Obesity

    Not yet reported Peking University Third Hospital 392 participants Est. completion 2027-12-31 1 site
    Other conditions: Polycystic Ovary Syndrome, Obesity, Infertility, Female
    View official trial listing →
  • Active, not recruiting NCT NCT06778967

    A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus

    Not yet reported Gan & Lee Pharmaceuticals. 1100 participants Est. completion 2026-12-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06793943

    A Study of Interaction of Zasocitinib (TAK-279) With Other Medicines in Healthy Adults

    Not yet reported Takeda 78 participants Est. completion 2025-03-30 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Not yet recruiting NCT NCT06840613

    Glucophage Plus Myo-Inositol vs Glucophage in Glycemic Control Among Patients With Gestational Diabetes Mellitus

    Not yet reported University of Health Sciences Lahore 90 participants Est. completion 2025-05
    Other conditions: Gestational Diabetes Mellitus (GDM)
    View official trial listing →
  • Completed NCT NCT06871761

    A Trial Comparing HR17031 With Insulin Glargine in Patients With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 393 participants Est. completion 2025-05-13 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06871904

    Fibrosis-Modulating Effects of Metformin and Pirfenidone in Oral Submucous Fibrosis

    Not yet reported, Not yet reported Ziauddin University 45 participants Est. completion 2025-12-30 1 site
    Other conditions: Oral Submucous Fibrosis
    View official trial listing →
  • Not yet recruiting NCT NCT06893978

    Placental Organoids Development: Application in the Study of the Human Reproduction Pathophysiology.

    Fondazione Policlinico Universitario Agostino Gemelli IRCCS 20 participants Est. completion 2027-11 1 site
    Other conditions: Preeclampsia, Pregnancy Loss, Preterm Birth, Healthy
    View official trial listing →
  • Active, not recruiting NCT NCT06899061

    Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib

    Not yet reported AstraZeneca 41 participants Est. completion 2028-05-19 4 sites
    Other conditions: Advanced Solid Malignancies
    View official trial listing →
  • Active, not recruiting NCT NCT06907472

    Diabetes Management for Primary Healthcare Centers.

    Not yet reported University of Abuja 106 participants Est. completion 2026-12-31 2 sites
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06911983

    Comparative Efficacy of Metformin and Berberine Among TCF7L2 (rs7903146) TT vs. CC Genotype Carriers With Type 2 Diabetes

    Not yet reported S.LAB (SOLOWAYS) 60 participants Est. completion 2026-03-01 1 site
    Other conditions: Diabetes Mellitis
    View official trial listing →
  • Completed NCT NCT06913881

    Comparative Cardiovascular Effectiveness of GLP-1 RAs vs. Insulin in Early-Onset Type 2 Diabetes

    Karolinska Institutet 92100 participants Est. completion 2025-01-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06920056

    A Study of BGM0504 in Overweight or Obese Participants

    Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 28 participants Est. completion 2025-07-25 1 site Stand-alone
    Other conditions: Overweight or Obese
    View official trial listing →
  • Not yet recruiting NCT NCT06946628

    New Triple Therapy in Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 296 participants Est. completion 2030-12-31 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Not yet recruiting NCT NCT06975839

    Local Metformin Gel and Impacted Lower Third Molar

    Not yet reported Fayoum University 36 participants Est. completion 2026-02-01
    Other conditions: Impacted Third Molar Tooth
    View official trial listing →
  • Completed NCT NCT06983223

    Oral Sucrosomial® Vitamin B12 in the Management of B12 Deficiency Among Metformin-Treated Type 2 Diabetes Patients

    Not yet reported Liaquat University of Medical & Health Sciences 50 participants Est. completion 2025-12-03 1 site
    Type 2 diabetes Other conditions: Vitamin B 12 Deficiency
    View official trial listing →
  • Withdrawn NCT NCT07007221

    Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV

    Not yet reported University of Minnesota Est. completion 2030-12-01
    Other conditions: Depression, Hiv
    View official trial listing →
  • Not yet recruiting NCT NCT07027969

    Metabolic Surgery for Atrial Fibrillation Elimination

    Not yet reported Ali Aminian 100 participants Est. completion 2030-03-31 1 site
    Other conditions: Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
    View official trial listing →
  • Active, not recruiting NCT NCT07055958

    Effect of Metformin as Add-on Therapy in Levodopa Treated Parkinson's Disease Patients

    Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 74 participants Est. completion 2025-07-20 1 site
    Other conditions: Parkinson Disease
    View official trial listing →
  • Completed NCT NCT07058675

    Myoinositol vs. Metformin for Polycystic Ovarian Syndrome (PCOS): Impact on Metabolic Health and Fertility

    Not yet reported Benha University 156 participants Est. completion 2025-06-18 1 site
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT07066722

    A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults

    Not yet reported ViiV Healthcare 126 participants Est. completion 2025-12-17 2 sites Stand-alone
    Other conditions: HIV Infections
    View official trial listing →
  • Enrolling by invitation NCT NCT07073768

    Comparison Between Efficacy of Trelagliptin and Sitagliptin in Type II Diabetic Patients

    Not yet reported Khyber Medical College, Peshawar 126 participants Est. completion 2026-12-30 1 site Stand-alone
    Type 2 diabetes Other conditions: Glycemic Control for Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT07077525

    Effect of Vildagliptin Versus Dapagliflozin as Add on Therapy to Metformin on Cardiovascular Risk Factors

    Not yet reported Al-Azhar University 196 participants Est. completion 2024-08-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07113756

    New Topical Treatment in Plaque Psoriasis

    Not yet reported Sohag University 70 participants Est. completion 2026-09-01
    Other conditions: Plaque Psoriasis
    View official trial listing →
  • Completed NCT NCT07121959

    A Study of Belzutifan (MK-6482) and Metformin in Healthy Adult Participants (MK-6482-039)

    Not yet reported Merck Sharp & Dohme LLC 14 participants Est. completion 2025-09-26 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT07145827

    Effect of Metformin on Endometrial Thickness in Postmenopausal Breast Cancer Patients Receiving Tamoxifen

    Not yet reported Uruk University 60 participants Est. completion 2025-07-01 1 site Stand-alone
    Other conditions: Breast Cancer, Endometrial Hyperplasia and Endometrial Cancers
    View official trial listing →
  • Completed NCT NCT07213895

    Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCL 25mg/5mg/1000mg Extended-Release Tablets Versus Trijardy® XR Extended Release Film Coated Tablets

    Not yet reported Humanis Saglık Anonim Sirketi 14 participants Est. completion 2025-09-18 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07216131

    A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years

    Not yet reported AstraZeneca 14 participants Est. completion 2025-12-30 1 site
    Other conditions: Healthy Participants
    View official trial listing →
  • Not yet recruiting NCT NCT07229534

    Clinical Trial to Evaluate the Efficacy and Safety of DA-5218 in Patients With Type 2 Diabetes

    Not yet reported Dong-A ST Co., Ltd. 238 participants Est. completion 2027-11
    Other conditions: Diabete Mellitus
    View official trial listing →
  • Not yet recruiting NCT NCT07241897

    DPP4 Inhibitor Intervention on Post-stroke Cognitive Impairment in Ischemic Stroke Patients With Type 2 Diabetes

    Not yet reported Second Affiliated Hospital of Soochow University 312 participants Est. completion 2028-04-30 1 site Stand-alone
    Cardiovascular disease Other conditions: Diabete Mellitus
    View official trial listing →
  • Active, not recruiting NCT NCT07279909

    Phase-III Clinical Studies on Poly Herbal Anti-Diabetic Formulation

    Not yet reported Hamdard University 500 participants Est. completion 2026-05-20 1 site
    Other conditions: Diabetes Type 2, Diabetes Mellitus, Experimental, HbA1c, Urinary Glucose, Ability of Experimental Drug to Lower HbA1c Compare to Metformin
    View official trial listing →
  • Not yet recruiting NCT NCT07300020

    PK and Relative Bioavailability of Novel Liquid Metformin vs Tablets

    Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-06-28 Stand-alone
    Other conditions: Healthy Volunteer
    View official trial listing →
  • Not yet recruiting NCT NCT07300046

    Tolerability Study of Liquid Metformin (100 and 250 mg/mL) vs IR Tablets

    Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-08-28
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Not yet recruiting NCT NCT07300059

    Short-Term Glycemic Effects of Liquid Metformin vs Standard Tablets

    Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-08-28
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT07303127

    Combination of Bitter Melon Extract and Snakehead Fish Powder to Reduce Glycaemia in Type 2 Diabetes Mellitus

    Not yet reported Universitas Muhammadiyah Surakarta 80 participants Est. completion 2021-10-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07323381

    Effects of Henagliflozin Proline and Metformin XR on Body Composition in Geriatric Patients With Newly Diagnosed T2DM

    Not yet reported Bin Lu 116 participants Est. completion 2027-09-30
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT07323589

    Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS

    Not yet reported PAEC general hospital 120 participants Est. completion 2025-10-25 1 site
    Other conditions: PCOS (Polycystic Ovary Syndrome)
    View official trial listing →
  • Completed NCT NCT07333742

    A Clinical Study to See How the Body Handles and How Safe a Combination Tablet of Gemigliptin, Dapagliflozin, and Metformin 50/10/1000mg is Compared to Taking Gemigliptin 50mg Separately With Dapagliflozin/Metformin 10/1000mg in Healthy Adults After a Meal

    Not yet reported LG Chem 50 participants Est. completion 2025-11-27 1 site
    Other conditions: Fed Conditions, Healthy Volunteer
    View official trial listing →
  • Completed NCT NCT07336914

    Effect of Conventional vs Intensive Management on Gestational Diabetes and Maternal Fetal Outcomes

    Not yet reported Khyber Medical University Peshawar 60 participants Est. completion 2026-04-25 2 sites Stand-alone
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT07363707

    A Study Between Dapagliflozin and Empagliflozin Effect on NAFLD in Patients With Type 2 Diabetes.

    Not yet reported Beni-Suef University 108 participants Est. completion 2024-03-01 1 site
    MASLD
    View official trial listing →
  • Not yet recruiting NCT NCT07395895

    Effect of Metformin Iontophoresis on Knee Osteoarthritis in Postmenopausal Women

    Not yet reported Badr University 68 participants Est. completion 2026-05-01 1 site
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT07396844

    The Food Effect on Pharmacokinetics of Fixed Dose Combination of Gemigliptin/Dapagliflozin/Metformin in Healthy Volunteers

    Not yet reported LG Chem 28 participants Est. completion 2026-06-26 1 site
    Other conditions: Healthy, Fasting, Fed
    View official trial listing →
  • Completed NCT NCT07399470

    A Clinical Study in Healthy Adults to See How the Body Processes and How Safe a Tablet That Combines Gemigliptin, Dapagliflozin, and Metformin is, Compared With Taking Zemiglo and Xigduo XR Together While Fasting.

    Not yet reported LG Chem 58 participants Est. completion 2026-02-06 1 site Stand-alone
    Other conditions: Healthy Volunteers, Fasting Conditions
    View official trial listing →
  • Not yet recruiting NCT NCT07417306

    A Study of HDM1005 in Participants With T2DM Not Controlled With Metformin Alone or in Combination With a Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor

    Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 912 participants Est. completion 2027-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07436182

    Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. Metformin Monotherapy

    Not yet reported Mansoura University 176 participants Est. completion 2026-06-01 1 site Stand-alone
    Other conditions: Mitochondria, Metformin
    View official trial listing →
  • Completed NCT NCT07451938

    A Cohort Study on Obese Patients' Multidisciplinary Integrated Health Management

    China-Japan Friendship Hospital 1500 participants Est. completion 2025-07-30 1 site
    Other conditions: Obesity, Diabete Type 2, Bariatric Surgery
    View official trial listing →
  • Completed NCT NCT07469254

    Adding 1% Metformin Gel to Bone Graft in Association With Immediate Dental Implants

    Not yet reported Al-Azhar University 20 participants Est. completion 2025-09-01 1 site Stand-alone
    Other conditions: Metformin Gel, Bone Graft, Immediate Dental Implants
    View official trial listing →
  • Active, not recruiting NCT NCT07475546

    Combination Gerotherapeutic Interventions for Healthspan Improvement

    Not yet reported AgelessRx 30 participants Est. completion 2026-04 1 site Stand-alone
    Other conditions: Healthspan Improvement, Aging, Longevity
    View official trial listing →
  • Completed NCT NCT07530289

    A Clinical Study of Ulonivirine (MK-8507) With Atorvastatin and Metformin in Healthy Adults (MK-8507-018)

    Not yet reported Merck Sharp & Dohme LLC 12 participants Est. completion 2026-06-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Not yet recruiting NCT NCT07536620

    Metformin and Alveolar Cleft

    Not yet reported Fayoum University 36 participants Est. completion 2027-05-30
    Other conditions: Alveolar Cleft
    View official trial listing →
  • Completed NCT NCT07541456

    Empagliflozin Versus Non-SGLT2 Oral Drugs for Blood Pressure in Type 2 Diabetes

    Not yet reported Dr. Zarmina Younes 300 participants Est. completion 2025-11-08 1 site
    Type 2 diabetes Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT07567781

    A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.

    Not yet reported AbbVie 12 participants Est. completion 2026-07-21 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT07585396

    Inositol in Letrozol Resistant PCOS Women

    Not yet reported, Not yet reported Kafrelsheikh University 136 participants Est. completion 2026-07-11 1 site
    Other conditions: Polycystic Ovary Syndrome, Infertility
    View official trial listing →
  • Not yet recruiting NCT NCT07589387

    Hypertension Treatment in Nigeria: Hypertension Diabetes Integration Study- Formative Aim 3

    Not yet reported Washington University School of Medicine 2800 participants Est. completion 2030-01-31
    Other conditions: Diabete Mellitus
    View official trial listing →
  • Completed NCT NCT07604870

    Krill Oil and Metformin in Women With PCOS and Metabolically Unhealthy Obesity

    Not yet reported Firat University 54 participants Est. completion 2024-04-30 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Obesity, Metabolic
    View official trial listing →
  • Completed NCT NCT07628556

    Antidiabetic Medications and Risk of Cancer

    University of Pecs 74799 participants Est. completion 2025-12-30 1 site
    Other conditions: Cancer
    View official trial listing →
  • Completed NCT NCT07633015

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 5 mg / 850 mg Tablets Under Fed Conditions.

    Not yet reported ADIUM 42 participants Est. completion 2025-04-29 1 site
    Other conditions: Bioequivalence Study in Healthy Subjects
    View official trial listing →
  • Completed NCT NCT07633028

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 850 mg Tablets Under Fed Conditions.

    Not yet reported ADIUM 42 participants Est. completion 2025-04-08 1 site Stand-alone
    Other conditions: Bioequivalence Study in Healthy Subjects
    View official trial listing →
  • Completed NCT NCT07633054

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 500 mg Tablets Under Fed Conditions.

    Not yet reported ADIUM 42 participants Est. completion 2025-11-24 1 site
    Other conditions: Bioequivalence Study in Healthy Subjects
    View official trial listing →
  • Not yet recruiting NCT NCT07647003

    A Study to Evaluate the Effect of Two Fixed-Dose Leucine, Sildenafil and Metformin Combinations on Blood Pressure in Individuals With Hypertension

    Not yet reported NuSirt Biopharma 150 participants Est. completion 2027-07-07 Stand-alone
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT07679711

    Bioequivalence Study of Sitagliptin/Metformin Extended-Release Tablets in Healthy Subjects

    Not yet reported The Affiliated Hospital of Qingdao University 76 participants Est. completion 2023-03-22 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Not yet recruiting NCT NCT07687667

    Effects of GLP-1RAs on Fertility Outcomes in Obese Women With PCOS

    Not yet reported Peking University Third Hospital 406 participants Est. completion 2029-12 1 site
    Other conditions: Polycystic Ovary Syndrome (PCOS), Obesity, Infertility, Female
    View official trial listing →
  • Completed NCT NCT07694115

    Bioequivalence Study to Compare Empagliflozin/ Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg

    Not yet reported Humanis Saglık Anonim Sirketi 40 participants Est. completion 2026-07-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07702669

    Modified Huanglian Wendan Decoction for Metabolic Syndrome

    Not yet reported First Affiliated Hospital of Heilongjiang Chinese Medicine University 180 participants Est. completion 2025-08-31 1 site Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT07763964

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fed Study.

    Not yet reported ADIUM 46 participants Est. completion 2025-12-19 1 site
    Other conditions: Bioequivalance
    View official trial listing →
  • Not yet recruiting NCT NCT07768280

    Efficacy and Safety of Hebenrun in Patients With Type 2 Diabetes

    Not yet reported Jiangxi University of Traditional Chinese Medicine 110 participants Est. completion 2028-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07770087

    Effect of Metformin Gel on Guided Bone Regeneration Around Immediate Dental Implant at Posterior Maxillary Region

    Not yet reported Al-Azhar University 12 participants Est. completion 2025-12-15 2 sites Stand-alone
    Other conditions: Metformin Gel, Bone Healing, Guided Bone Regeneration, Crestal Bone Loss, Peri Implant Bone Loss
    View official trial listing →
  • Not yet recruiting NCT NCT07770711

    Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS

    Not yet reported Dicle University 90 participants Est. completion 2027-06 1 site
    Other conditions: PCOS (Polycystic Ovary Syndrome), Insulin Resistance, Obesity (BMI>30)
    View official trial listing →
  • Completed NCT NCT07793838

    Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS

    Not yet reported Jerash Private University 400 participants Est. completion 2026-08-01 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome (PCOS) Women
    View official trial listing →
  • Not yet recruiting NCT NCT07796477

    A Study of SYH2069 Injection in Participants With T2DM Not Controlled With Diet/Exercise Alone or Metformin

    Not yet reported CSPC Ouyi Pharmaceutical Co., Ltd. 240 participants Est. completion 2027-10-19 1 site
    Type 2 diabetes
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources
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