GLP-1 Market
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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Metformin

Company
Ziauddin University
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
167 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

167 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Oct 1, 2026

Find a Clinical Trial Near Me

See recruiting studies for Metformin and check eligibility with the study team.

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Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT01042379

    I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

    Not yet reported QuantumLeap Healthcare Collaborative 5000 participants Est. completion 2031-12 42 sites
    Obstructive sleep apnea Other conditions: Breast Neoplasms, Breast Cancer, Breast Tumors, TNBC - Triple-Negative Breast Cancer, HER2-positive Breast Cancer, HER2-negative Breast Cancer, Hormone Receptor Positive Tumor, Hormone Receptor Negative Tumor, Early-stage Breast Cancer, Locally Advanced Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT01638676

    A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients

    Not yet reported, Not yet reported University of Louisville 55 participants Est. completion 2027-06 1 site Stand-alone
    Other conditions: Melanoma
    View official trial listing →
  • Recruiting NCT NCT02647827

    Acupuncture or Metformin for Insulin Resistance in Women With PCOS

    Not yet reported Karolinska Institutet 303 participants Est. completion 2026-06 2 sites
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance, Hyperandrogenism
    View official trial listing →
  • Recruiting NCT NCT02915198

    Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

    Not yet reported VA Office of Research and Development 7410 participants Est. completion 2029-09-28 40 sites Stand-alone
    Other conditions: Prediabetic State, Atherosclerosis, Metformin
    View official trial listing →
  • Recruiting NCT NCT02947503

    Pregnancy Outcomes: Effects of Metformin Study (POEM Study)

    Not yet reported Bethesda Diabetes Research Center 500 participants Est. completion 2043-12 4 sites
    Other conditions: Gestational Diabetes, Insulin Resistance
    View official trial listing →
  • Recruiting NCT NCT02969798

    Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

    Not yet reported The University of Texas Health Science Center at San Antonio 700 participants Est. completion 2027-07 1 site
    Type 2 diabetesPrediabetes
    View official trial listing →
  • Recruiting NCT NCT03379909

    Phase II Study of Oral Metformin for Intravesical Treatment of Non-muscle-invasive Bladder Cancer

    Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 49 participants Est. completion 2029-10-01 3 sites Stand-alone
    Other conditions: Superficial Bladder Cancer, Bladder Cancer
    View official trial listing →
  • Recruiting NCT NCT03424005

    A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

    Not yet reported, Not yet reported Hoffmann-La Roche 1132 participants Est. completion 2030-09-30 53 sites Stand-alone
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT03511118

    Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

    Duke University 1600 participants Est. completion 2028-07-31 22 sites
    Other conditions: Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOI
    View official trial listing →
  • Recruiting NCT NCT03568630

    Blood Markers of Early Pancreas Cancer

    University of Nebraska 1250 participants Est. completion 2028-07 1 site
    Type 2 diabetesPrediabetes Other conditions: Pancreas Cyst, Chronic Pancreatitis, Genetic Predisposition to Disease, Inherited Disease
    View official trial listing →
  • Recruiting NCT NCT03675893

    RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial Cancer

    Not yet reported Dana-Farber Cancer Institute 110 participants Est. completion 2031-08-01 3 sites Stand-alone
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Recruiting NCT NCT03925701

    Clinical Study Evaluating Vildagliptin Versus Vildagliptin/Metformin on NAFLD With DM

    Not yet reported Sherief Abd-Elsalam 120 participants Est. completion 2028-12 1 site
    Other conditions: dm
    View official trial listing →
  • Recruiting NCT NCT03925714

    Impact of P53 and SIRT1 in Type 2 Diabetes

    Not yet reported Sherief Abd-Elsalam 90 participants Est. completion 2028-12 1 site
    Other conditions: DM
    View official trial listing →
  • Recruiting NCT NCT03989778

    Vitamin D and Polycystic Ovarian Syndrome (PCOS)

    Not yet reported Aga Khan University 300 participants Est. completion 2025-07-13 2 sites Stand-alone
    Other conditions: Infertility, Female, Infertility, Vitamin D Deficiency
    View official trial listing →
  • Recruiting NCT NCT04114136

    Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies

    Not yet reported Dan Zandberg 72 participants Est. completion 2032-04-30 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Melanoma, NSCLC, Hepatocellular Carcinoma, Urothelial Cancer, Gastric Adenocarcinoma, HNSCC, Esophageal Adenocarcinoma
    View official trial listing →
  • Recruiting NCT NCT04121468

    A Phase I Double Blind Study of Metformin Acting on Endogenous Neural Progenitor Cells in Children and Young Adults With Multiple Sclerosis

    Not yet reported, Not yet reported The Hospital for Sick Children 20 participants Est. completion 2027-10 1 site
    Other conditions: Multiple Sclerosis (MS)
    View official trial listing →
  • Recruiting NCT NCT04278404

    Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

    Duke University 5000 participants Est. completion 2026-12 52 sites
    Heart failure Other conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
    View official trial listing →
  • Recruiting NCT NCT04500678

    Impact of Metformin on Immuno-virologic Parameters in HIV

    Not yet reported, Not yet reported University of Hawaii 38 participants Est. completion 2022-12-31 1 site Stand-alone
    Other conditions: HIV/AIDS
    View official trial listing →
  • Recruiting NCT NCT04500756

    Limiting AAA With Metformin (LIMIT) Trial

    Not yet reported Stanford University 314 participants Est. completion 2028-06-30 1 site
    Other conditions: Abdominal Aortic Aneurysm
    View official trial listing →
  • Recruiting NCT NCT04530383

    Metformin for People With CFRD on CFTR Modulator Therapy to Improve Ion Channel Function

    Not yet reported University of Kansas Medical Center 30 participants Est. completion 2028-07-15 1 site Stand-alone
    Other conditions: Cystic Fibrosis-related Diabetes, Cystic Fibrosis
    View official trial listing →
  • Recruiting NCT NCT04578652

    Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance

    Not yet reported University of Alberta 90 participants Est. completion 2026-09 1 site Stand-alone
    Other conditions: Obesity, Childhood, Insulin Resistance
    View official trial listing →
  • Recruiting NCT NCT04581447

    Extending Time Without Diabetes After Bariatric Surgery: a Trial Comparing the Metformin Addition or Not to Standard Care

    Not yet reported Assistance Publique - Hôpitaux de Paris 126 participants Est. completion 2026-11 16 sites Stand-alone
    Other conditions: Diabetes, Bariatric Surgery, Metformin
    View official trial listing →
  • Recruiting NCT NCT04670666

    Efficacy and Safety of Madalena Association in the Treatment of Type II Diabetes Mellitus

    Not yet reported EMS 270 participants Est. completion 2027-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT04741945

    Repurposing Metformin As a Leukemia-preventive Drug in CCUS and LR-MDS

    Not yet reported Kirsten Grønbæk 40 participants Est. completion 2026-02 1 site Stand-alone
    Other conditions: Preleukemia, Myelodysplastic Neoplasm, Cytopenia, Preleukemic Anemia
    View official trial listing →
  • Recruiting NCT NCT04758000

    Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse

    Not yet reported Istituto Ortopedico Rizzoli 67 participants Est. completion 2027-07 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Ewing Sarcoma
    View official trial listing →
  • Recruiting NCT NCT04939935

    Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)

    Not yet reported The University of Queensland 1174 participants Est. completion 2030-12 49 sites Stand-alone
    Other conditions: Autosomal Dominant Polycystic Kidney Disease
    View official trial listing →
  • Recruiting NCT NCT04945148

    Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide

    Not yet reported Hopital Foch 640 participants Est. completion 2028-05 7 sites Stand-alone
    Other conditions: Glioblastoma, IDH-wildtype
    View official trial listing →
  • Recruiting NCT NCT05036226

    COAST Therapy in Advanced Solid Tumors and Prostate Cancer

    Not yet reported, Not yet reported Medical University of South Carolina 76 participants Est. completion 2028-05-21 1 site Stand-alone
    Other conditions: Prostate Cancer Recurrent, Solid Tumor, Adult
    View official trial listing →
  • Recruiting NCT NCT05041907

    Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)

    Not yet reported University of Oxford 3800 participants Est. completion 2027-01 7 sites Stand-alone
    Other conditions: COVID-19
    View official trial listing →
  • Recruiting NCT NCT05065372

    MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes

    Not yet reported Kalie Tommerdahl 60 participants Est. completion 2027-07-31 2 sites
    Chronic kidney diseaseCardiovascular disease Other conditions: Type 1 Diabetes, Endothelial Dysfunction, Insulin Sensitivity
    View official trial listing →
  • Recruiting NCT NCT05132439

    MetfOrmin BenefIts Lower Extremities With Intermittent Claudication

    Not yet reported VA Office of Research and Development 200 participants Est. completion 2032-02-28 1 site Stand-alone
    Alcohol use disorder
    View official trial listing →
  • Recruiting NCT NCT05164263

    Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study

    Not yet reported Getz Pharma 2000 participants Est. completion 2027-08-31 6 sites Stand-alone
    Other conditions: Type II Diabetes Mellitus, Efficacy, Self, Safety Issues
    View official trial listing →
  • Recruiting NCT NCT05205317

    Comparison of the Therapeutic Effects of VR and VR + Metformin in the Treatment of Cesarean Section Scar Defect

    Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 100 participants Est. completion 2027-06-30 1 site Stand-alone
    Other conditions: Defect
    View official trial listing →
  • Recruiting NCT NCT05230758

    Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour

    Not yet reported Donald Mabbott 140 participants Est. completion 2027-11-30 20 sites Stand-alone
    Other conditions: Medulloblastoma, Childhood, Cognitive Impairment
    View official trial listing →
  • Recruiting NCT NCT05243654

    Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy

    Not yet reported Oxford University Clinical Research Unit Indonesia 166 participants Est. completion 2026-09-30 6 sites Stand-alone
    Other conditions: Leprosy, Leprosy, Multibacillary, Neglected Tropical Diseases
    View official trial listing →
  • Recruiting NCT NCT05316935

    GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients

    Not yet reported, Not yet reported Xiaojun Chen 80 participants Est. completion 2028-03-30 2 sites Stand-alone
    Other conditions: Endometrial Neoplasms, Atypical Endometrial Hyperplasia, Progesterone Resistance
    View official trial listing →
  • Recruiting NCT NCT05345327

    SGLT2 Inhibitors As First Line Therapy to Prevent Renal Decline in Type 2 Diabetes

    Not yet reported The George Institute 994 participants Est. completion 2026-06-30 8 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT05414409

    The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

    Not yet reported Heba M. Ismail 114 participants Est. completion 2027-03-01 1 site Stand-alone
    Other conditions: Type 1 Diabetes, Obesity
    View official trial listing →
  • Recruiting NCT NCT05426044

    Metformin as a Neuroprotective Therapy for Glaucoma

    Not yet reported Christopher Kai Shun Leung 125 participants Est. completion 2027-12-31 1 site
    Other conditions: Glaucoma
    View official trial listing →
  • Recruiting NCT NCT05469659

    Effect of Tofogliflozin on UACR Compared to Metformin Hydrochloride in Diabetic Kidney Disease (TRUTH-DKD)

    Not yet reported Shinshu University 120 participants Est. completion 2026-10-30 1 site
    Type 2 diabetes Other conditions: Metformin, SGLT2-Inhibitors
    View official trial listing →
  • Recruiting NCT NCT05515978

    Pragmatic Trial of Metformin for Glucose Intolerance or Increased BMI in Prostate Cancer Patients

    Not yet reported University of Colorado, Denver 100 participants Est. completion 2036-11-06 4 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Recruiting NCT NCT05532813

    Evaluation of the Efficacy and Safety of Metformin in the Myotonic Dystrophy Type 1 (Steinert's Disease)

    Not yet reported Assistance Publique - Hôpitaux de Paris 142 participants Est. completion 2026-12 1 site Stand-alone
    Other conditions: Steinert's Disease, Myotonic Dystrophy 1, Metformin
    View official trial listing →
  • Recruiting NCT NCT05574387

    Metformin as Added on Therapy in Patients With Ulcerative Colitis

    Not yet reported Tanta University 46 participants Est. completion 2027-04 1 site
    Other conditions: Inflammatory Bowel Diseases
    View official trial listing →
  • Recruiting NCT NCT05660083

    Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)

    Not yet reported The Methodist Hospital Research Institute 36 participants Est. completion 2028-12-02 3 sites Stand-alone
    Other conditions: HER2-negative Breast Cancer, Metastatic Breast Cancer, Metaplastic Breast Carcinoma, TNBC - Triple-Negative Breast Cancer
    View official trial listing →
  • Recruiting NCT NCT05727761

    Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia

    Not yet reported University of Minnesota 36 participants Est. completion 2027-07-30 2 sites Stand-alone
    Other conditions: Oral Leukoplakia
    View official trial listing →
  • Recruiting NCT NCT05744479

    Metformin for Antipsychotic-induced Weight Gain in Adults With Intellectual Disability

    Not yet reported Centre for Addiction and Mental Health 100 participants Est. completion 2027-03-01 1 site Stand-alone
    Other conditions: Intellectual Disability, Developmental Disability, Obesity
    View official trial listing →
  • Recruiting NCT NCT05768139

    First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

    Not yet reported, Not yet reported Eli Lilly and Company 880 participants Est. completion 2030-07 65 sites Stand-alone
    Other conditions: Breast Cancer, Solid Tumors, Adult
    View official trial listing →
  • Recruiting NCT NCT05819853

    Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome

    Not yet reported University of Colorado, Denver 80 participants Est. completion 2028-06-30 1 site Added to GLP-1
    Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Obese
    View official trial listing →
  • Recruiting NCT NCT05900466

    Metformin for Fibromyalgia Symptoms (INFORM Trial)

    Not yet reported University of Utah 72 participants Est. completion 2027-03-31 1 site
    Other conditions: Fibromyalgia Syndrome
    View official trial listing →
  • Recruiting NCT NCT05917587

    Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

    Not yet reported Anna Stanhewicz, PhD 30 participants Est. completion 2028-06-30 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Recruiting NCT NCT05929495

    Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma

    Not yet reported University of Milano Bicocca 25 participants Est. completion 2026-01-01 1 site Stand-alone
    Other conditions: Glioblastoma, IDH-wildtype, Metformin, Malignancies
    View official trial listing →
  • Recruiting NCT NCT06030622

    Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer

    Not yet reported, Not yet reported State University of New York - Downstate Medical Center 25 participants Est. completion 2028-12-30 1 site Stand-alone
    Other conditions: Pancreatic Cancer Metastatic
    View official trial listing →
  • Recruiting NCT NCT06033131

    PI4 - A Trial Assessing Metformin to Prolong Gestation in Preterm Preeclampsia

    Not yet reported Lina Bergman 294 participants Est. completion 2029-12-31 18 sites
    Other conditions: Preeclampsia
    View official trial listing →
  • Recruiting NCT NCT06044025

    A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy

    Not yet reported University of Arkansas 34 participants Est. completion 2028-10 1 site Stand-alone
    Other conditions: Castration Sensitive Prostate Cancer
    View official trial listing →
  • Recruiting NCT NCT06045351

    Efficacy of Injectable Vitamin D Supplementation in Females With Polycystic Ovary Syndrome

    Not yet reported Aga Khan University 142 participants Est. completion 2026-12-31 1 site Stand-alone
    Other conditions: Anovulatory Infertility
    View official trial listing →
  • Recruiting NCT NCT06064669

    Effect of Metformin on Healthy Live Birth in Women With Prediabetes

    Not yet reported Shandong University 988 participants Est. completion 2027-12-31 1 site Stand-alone
    Prediabetes Other conditions: Metformin, In-Vitro Fertilization
    View official trial listing →
  • Recruiting NCT NCT06090227

    AMPK-activation by Metformin in FSGS: AMP-FSGS

    Not yet reported, Not yet reported Yale University 30 participants Est. completion 2027-11 2 sites Stand-alone
    Other conditions: Focal Segmental Glomerulosclerosis
    View official trial listing →
  • Recruiting NCT NCT06096259

    Preventing Injured Knees From osteoArthritis: Severity Outcomes

    Not yet reported Brigham and Women's Hospital 512 participants Est. completion 2029-12 9 sites Stand-alone
    Osteoarthritis Other conditions: ACL Tear
    View official trial listing →
  • Recruiting NCT NCT06120881

    Precision Dosing of Metformin in Youth With T2D

    Not yet reported University of California, San Francisco 20 participants Est. completion 2026-12-31 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06142656

    Efficacy of Vildagliptin Versus Metformin in Poly Cystic Ovary Syndrome

    Not yet reported, Not yet reported October 6 University 60 participants Est. completion 2026-02-01 1 site
    Other conditions: Poly Cystic Ovary Syndrome
    View official trial listing →
  • Recruiting NCT NCT06185179

    Metformin and Muscle Recovery

    Not yet reported University of Utah 50 participants Est. completion 2030-05-31 1 site Stand-alone
    Other conditions: Muscle Atrophy or Weakness
    View official trial listing →
  • Recruiting NCT NCT06231758

    Metformin Safety and Efficacy in Osteoarthritis.

    Not yet reported Mostafa Bahaa 70 participants Est. completion 2027-11-20 1 site
    Other conditions: Osteo Arthritis Knee
    View official trial listing →
  • Recruiting NCT NCT06246799

    Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

    Not yet reported The University of Texas Health Science Center at San Antonio 256 participants Est. completion 2029-06-30 2 sites
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06273072

    Metformin IN Asthma for Overweight and Obese Individuals (MINA)

    Not yet reported Johns Hopkins University 100 participants Est. completion 2028-12-31 2 sites
    Other conditions: Asthma, Asthma Chronic, Overweight and Obesity
    View official trial listing →
  • Recruiting NCT NCT06318442

    The GAPSID Study - How GLP-1 Analogues Prevent Steroid-Induced Diabetes

    Not yet reported Imperial College London 60 participants Est. completion 2027-06-01 1 site
    Other conditions: Steroid-Induced Diabetes, Steroid Induced Hyperglycemia
    View official trial listing →
  • Recruiting NCT NCT06319560

    Hydroxychloroquine in Type 2 Diabetes During Pregnancy

    Not yet reported National University of Malaysia 56 participants Est. completion 2027-01-01 1 site
    Type 2 diabetes Other conditions: Diabetes in Pregnancy
    View official trial listing →
  • Recruiting NCT NCT06367283

    Metformin Treatment of Patients with Hand Osteoarthritis

    Not yet reported Marius Henriksen 150 participants Est. completion 2026-04 1 site Stand-alone
    Osteoarthritis
    View official trial listing →
  • Recruiting NCT NCT06377696

    Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

    Not yet reported Mayo Clinic 100 participants Est. completion 2027-05-01 1 site Stand-alone
    Other conditions: Malignant Brain Neoplasm
    View official trial listing →
  • Recruiting NCT NCT06399835

    Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis

    Not yet reported Seoul National University Bundang Hospital 120 participants Est. completion 2027-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06424860

    Fish Oil, Metformin and Heart Health in PCOS

    Not yet reported University of Alberta 146 participants Est. completion 2027-12-30 3 sites Stand-alone
    Cardiovascular disease Other conditions: PCOS, Atherosclerotic Plaque, Cardiac Hypertrophy
    View official trial listing →
  • Recruiting NCT NCT06445946

    DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

    Not yet reported Ohio State University 1572 participants Est. completion 2030-12 24 sites Stand-alone
    Other conditions: Gestational Diabetes Mellitus, Pregnancy, High Risk
    View official trial listing →
  • Recruiting NCT NCT06449833

    Effect of Henagliflozein on Hepatic Fat Content in Patients With T2DM and NAFLD

    Not yet reported Zhujiang Hospital 100 participants Est. completion 2026-11 1 site Stand-alone
    Type 2 diabetesMASLD
    View official trial listing →
  • Recruiting NCT NCT06459310

    Pilot Study on Evaluating the Geroprotective Effect of Metformin

    Not yet reported Xuanwu Hospital, Beijing 130 participants Est. completion 2028-07-31 1 site Stand-alone
    Other conditions: Metformin, Aging
    View official trial listing →
  • Recruiting NCT NCT06463743

    Metformin as an add-on or Monotherapy in Treatment of Aging People With Multiple Sclerosis (MS)

    Not yet reported State University of New York at Buffalo 30 participants Est. completion 2027-06-01 1 site Stand-alone
    Other conditions: Multiple Sclerosis
    View official trial listing →
  • Recruiting NCT NCT06528405

    The Efficacy and Safety of Sodium-glucose Cotransporter 2 Inhibitors in Patients With Acute Kidney Disease

    Not yet reported National Taiwan University Hospital 264 participants Est. completion 2027-12 1 site
    Other conditions: Acute Kidney Injury
    View official trial listing →
  • Recruiting NCT NCT06537843

    Safety and Efficacy of Venetoclax, Cytarabine and Metformin (VenCM) for Relapsed-Refractory and Induction-Ineligible Acute Myeloid Leukemia

    Not yet reported Hospital Municipal São José 100 participants Est. completion 2028-07-01 5 sites Stand-alone
    Other conditions: Acute Myeloid Leukemia
    View official trial listing →
  • Recruiting NCT NCT06591169

    Lifestyle Changes in PCOS with OSA and NAFLD

    Not yet reported Cairo University 40 participants Est. completion 2024-12-15 2 sites Stand-alone
    MASLDObstructive sleep apnea Other conditions: PCOS
    View official trial listing →
  • Recruiting NCT NCT06613854

    Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in Individuals With Type 2 Diabetes

    Not yet reported University Medical Centre Ljubljana 90 participants Est. completion 2027-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06627322

    A Registry-based Randomized Controlled Trial in Type 2 Diabetes With Cardiovascular Risk Factors (REMATCH)

    Not yet reported Kyu Chang Won 5950 participants Est. completion 2029-09-30 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06661174

    A Cohort Study on the Efficacy of Bariatric Surgery for Rapidly Progressing Diabetic Nephropathy

    China-Japan Friendship Hospital 100 participants Est. completion 2025-10-30 1 site
    Chronic kidney disease Other conditions: Bariatric Surgeries
    View official trial listing →
  • Recruiting NCT NCT06682130

    Glofitamab Bridging ASCT for Patients With Relapsed or Refractory DLBCL

    Not yet reported The First Affiliated Hospital of Soochow University 40 participants Est. completion 2029-11-10 1 site Stand-alone
    Other conditions: Diffuse Large B-cell Lymphoma(DLBCL)
    View official trial listing →
  • Recruiting NCT NCT06686043

    HPV Vaccine, Imiquimod, and Metformin Combination Trial

    Not yet reported Baylor College of Medicine 85 participants Est. completion 2028-08-23 2 sites Stand-alone
    Other conditions: Cervical Carcinoma, Vaginal Carcinoma, Vulvar Carcinoma, HPV (Human Papillomavirus)-Associated Carcinoma
    View official trial listing →
  • Recruiting NCT NCT06687876

    Metformin as a Metabolic Intervention in Oesophageal Adenocarcinomas to Improve Response to Neoadjuvant Chemoradiotherapy

    Not yet reported Amsterdam UMC, location VUmc 14 participants Est. completion 2030-12 2 sites Stand-alone
    Other conditions: Oesophageal Adenocarcinoma, Tumor Microenvironment
    View official trial listing →
  • Recruiting NCT NCT06693934

    Jockey Club Precision Prevention Programme on Young Onset Diabetes

    Not yet reported Juliana CN Chan 9000 participants Est. completion 2028-05 1 site
    Other conditions: Diabetes, Pre Diabetes, Hypertension, Dyslipidemia, Obesity
    View official trial listing →
  • Recruiting NCT NCT06707012

    Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese Patients

    Not yet reported Fazaia Ruth Pfau Medical College 140 participants Est. completion 2026-12 2 sites Stand-alone
    Other conditions: Depression
    View official trial listing →
  • Recruiting NCT NCT06716216

    A Study of BGM0504 in Participants with Type 2 Diabetes

    Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 537 participants Est. completion 2026-11-14 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06742710

    Liraglutide Treatment in Obese Infertile PCOS Women

    Not yet reported Peking University Third Hospital 890 participants Est. completion 2029-12-31 3 sites Added to GLP-1
    Other conditions: PCOS, Obesity, Infertility
    View official trial listing →
  • Recruiting NCT NCT06763328

    Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy

    Not yet reported City of Hope Medical Center 80 participants Est. completion 2029-06-16 3 sites Stand-alone
    Other conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Invasive Breast Carcinoma
    View official trial listing →
  • Recruiting NCT NCT06781775

    GDM: Insulin with or Without Metformin?

    Not yet reported University of Virginia 130 participants Est. completion 2027-05-01 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Recruiting NCT NCT06806345

    Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause

    Not yet reported, Not yet reported Cairo University 40 participants Est. completion 2025-04-28 1 site Stand-alone
    Other conditions: Insulin Resistance Syndrome
    View official trial listing →
  • Recruiting NCT NCT06826092

    Metformin for the Treatment of mCRC Patients Undergoing FOLFIRI Plus Target Therapy

    Not yet reported Kaohsiung Medical University Chung-Ho Memorial Hospital 110 participants Est. completion 2025-12-31 1 site Stand-alone
    Other conditions: Progression-Free Survival
    View official trial listing →
  • Recruiting NCT NCT06829238

    Assessment of Metformin for Restoration of Immune Homeostasis in HIV+ and HIV- Individuals With a History of Injection Drug Use

    Not yet reported University of Alabama at Birmingham 100 participants Est. completion 2029-11-30 1 site Stand-alone
    Other conditions: Systemic Inflammation, Immune Dysregulation, Injection Drug Use, HIV
    View official trial listing →
  • Recruiting NCT NCT06836128

    The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients

    Not yet reported Cairo University 102 participants Est. completion 2026-05-01 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Recruiting NCT NCT06838286

    Korean Study on Safety and Effectiveness of OAD Triple Therapy in Type 2 Diabetes

    Chong Kun Dang Pharmaceutical 10000 participants Est. completion 2029-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06845540

    Oral Metformin for Treating Melasma in Latin American Women

    Not yet reported, Not yet reported University of Puerto Rico 30 participants Est. completion 2025-05-30 1 site Stand-alone
    Other conditions: Melasma
    View official trial listing →
  • Recruiting NCT NCT06846411

    The EMPA-FIT Study

    Not yet reported Seoul National University Bundang Hospital 46 participants Est. completion 2025-12-31 1 site Stand-alone
    Other conditions: Diabetes, Diabetes Mellitus, Type II
    View official trial listing →
  • Recruiting NCT NCT06862739

    Glycemic Control With Triple Pathway Approach Through Empagliflozin, Linagliptin and Metformin Combination

    Not yet reported Nabiqasim Industries (Pvt) Ltd 800 participants Est. completion 2026-06-30 2 sites
    Other conditions: Diabetes Mellitus, Type 2 DM
    View official trial listing →
  • Recruiting NCT NCT06863532

    Efficacy and Safety Comparison of Cofrogliptin Add-on Versus Metformin Dose-escalation in Type 2 Diabetes Patients Inadequately Controlled With SGLT-2 Inhibitors Plus Low-Dose Metformin:A Multicenter, Open-Label Trial

    Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 80 participants Est. completion 2026-09-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06875193

    DM Treatment to Evaluate the Efficacy and Safety of Dapagliflozin or Pioglitazone in Patients with Type 2 Diabetes

    Not yet reported Dong Wha Pharmaceutical Co. Ltd. 196 participants Est. completion 2025-12-31 1 site
    Other conditions: Type2diabetes
    View official trial listing →
  • Recruiting NCT NCT06888050

    Efficacy and Safety of Henagliflozin Proline and Metformin Hydrochloride Extended-release Tablets (Ⅰ) Versus Metformin Tablets in Patients With New-onset Type 2 Diabetes: a Multicenter, Randomized Controlled Study

    Not yet reported Zhejiang Provincial People's Hospital 268 participants Est. completion 2026-12-30 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06889454

    Cardiovascular and Endothelial Markers During OGTT Before and at Six and Twelve Months Post-treatment in Women With PCOS

    Attikon Hospital 120 participants Est. completion 2026-02-01 1 site
    Metabolic syndrome Other conditions: PCOS, Hyperinsulinism, Hyperandrogenism
    View official trial listing →
  • Recruiting NCT NCT06896981

    Semaglutide in Women With Polycystic Ovary Syndrome and Obesity

    Not yet reported, Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 30 participants Est. completion 2025-12-31 1 site Added to GLP-1
    Other conditions: Polycystic Ovary Syndrome (PCOS) Women, Obesity
    View official trial listing →
  • Recruiting NCT NCT06924658

    Metformin in Safety and Efficacy in Gouty Patients

    Not yet reported Mostafa Bahaa 70 participants Est. completion 2027-11-20 1 site
    Other conditions: Gout
    View official trial listing →
  • Recruiting NCT NCT06937294

    Metformin in Post Chronic Pancreatitis Diabetes Mellitus

    Not yet reported Changhai Hospital 58 participants Est. completion 2026-01-31 1 site Stand-alone
    Other conditions: Chronic Pancreatitis
    View official trial listing →
  • Recruiting NCT NCT06948825

    Effectiveness Study of a Lifestyle Intervention Versus Metformin in Mothers With Recent Gestational Diabetes

    Not yet reported George Washington University 60 participants Est. completion 2026-11 1 site
    Other conditions: Weight Loss, Gestational Diabetes Mellitus in Pregnancy, Postpartum Care
    View official trial listing →
  • Recruiting NCT NCT06972732

    A Phase IV Clinical Trial to Compare the Efficacy and Safety of Metformin+Sodium-Glucose Cotransporter 2 Inhibitor(SGLT2-i)+Thiazolidinedione (TZD) in Patients With Type 2 Diabetes

    Not yet reported Boryung Pharmaceutical Co., Ltd 204 participants Est. completion 2026-10-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT06975111

    Focusing on the Menopausal Transition to Improve Mid-Life Women's Health

    Not yet reported, Not yet reported University of Colorado, Denver 200 participants Est. completion 2030-10-01 3 sites
    Other conditions: Menopause, Menopause Hot Flashes, Menopause Related Conditions, Cardiovascular
    View official trial listing →
  • Recruiting NCT NCT07001878

    Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis

    Not yet reported Nova Scotia Health Authority 24 participants Est. completion 2026-12-01 2 sites Stand-alone
    Other conditions: Psychosis, Cannabis Use
    View official trial listing →
  • Recruiting NCT NCT07019012

    Cofrogliptin Once Every 2 Weeks as Add-on Therapy to Metformin and Dapagliflozin Versus Daily Linagliptin in Patients With Type 2 Diabetes.

    Not yet reported Huazhong University of Science and Technology 170 participants Est. completion 2026-12-30 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07045142

    Metformin Alleviates Abnormal Glucose Metabolism Induced by Statins in Schizophrenia Patients

    Not yet reported Central South University 400 participants Est. completion 2028-06-01 8 sites
    Other conditions: Schizophrenia
    View official trial listing →
  • Recruiting NCT NCT07064486

    A Study of BGM0504 in Participants With Type 2 Diabetes in Indonesia

    Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 477 participants Est. completion 2026-07-31 4 sites
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07065591

    Anti-Diabetic Drug, Exercise and Healthy Diet for Knee Osteoarthritis With Overweight/Obesity

    Not yet reported The University of Hong Kong 100 participants Est. completion 2028-07-17 1 site Stand-alone
    Osteoarthritis
    View official trial listing →
  • Recruiting NCT NCT07072221

    Bendamustine Combined With Chidamide and Lenalidomide for Relapsed and Refractory PTCL Patients

    Not yet reported The First Affiliated Hospital of Soochow University 40 participants Est. completion 2029-11-01 1 site Stand-alone
    Other conditions: Peripheral T-cell Lymphoma
    View official trial listing →
  • Recruiting NCT NCT07074379

    Endotherapy and/or Extracorporeal Shockwave Lithotripsy for Painless Chronic Pancreatitis

    Not yet reported Changhai Hospital 126 participants Est. completion 2037-07-01 1 site Stand-alone
    Other conditions: Painless Chronic Pancreatitis
    View official trial listing →
  • Recruiting NCT NCT07082114

    A Phase 3 Study to Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus

    Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 800 participants Est. completion 2027-05-17 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07083388

    A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fasting)

    Not yet reported Boryung Pharmaceutical Co., Ltd 52 participants Est. completion 2026-07-03 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Recruiting NCT NCT07083401

    A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fed)

    Not yet reported Boryung Pharmaceutical Co., Ltd 40 participants Est. completion 2026-07-05 1 site Stand-alone
    Other conditions: Diabete Mellitus
    View official trial listing →
  • Recruiting NCT NCT07092618

    Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation

    Not yet reported, Not yet reported AgelessRx 150 participants Est. completion 2025-08 1 site Stand-alone
    Other conditions: Longevity, GLP-1, Geroscience, Aging
    View official trial listing →
  • Recruiting NCT NCT07093476

    Efficacy and Safety of Add-On Therapy With Empagliflozin in Patients With Type 2 Diabetes on a Background of Alogliptin and Metformin

    Not yet reported Celltrion 171 participants Est. completion 2027-04 1 site
    Type 2 diabetes Other conditions: Diabete Type 2, DM
    View official trial listing →
  • Recruiting NCT NCT07098299

    Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies

    Not yet reported Barbara Ann Karmanos Cancer Institute 60 participants Est. completion 2028-07-07 10 sites Stand-alone
    Other conditions: Advanced Solid Tumor
    View official trial listing →
  • Recruiting NCT NCT07108075

    Acute Portal Pressure Reduction by Metformin and Carvedilol Compared to Carvedilol Alone in Cirrhosis.

    Not yet reported Institute of Liver and Biliary Sciences, India 72 participants Est. completion 2025-10-30 1 site Stand-alone
    Other conditions: Liver Cirrhosis
    View official trial listing →
  • Recruiting NCT NCT07109700

    A Study of HDM1005 in Participants With T2DM Not Controlled With Diet/Exercise or Metformin

    Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 216 participants Est. completion 2026-02-28 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07120971

    Metformin for Premature Infants With Bronchopulmonary Dysplasia

    Not yet reported Medical College of Wisconsin 40 participants Est. completion 2030-09-01 1 site Stand-alone
    Other conditions: Bronchopulmonary Dysplasia (BPD)
    View official trial listing →
  • Recruiting NCT NCT07129473

    Hyperemesis Gravidarum Risk Reduction With Metformin

    Not yet reported, Not yet reported University of Southern California 224 participants Est. completion 2031-03 2 sites Stand-alone
    Other conditions: Hyperemesis Gravidarum
    View official trial listing →
  • Recruiting NCT NCT07131384

    Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes

    Not yet reported University of Virginia 24 participants Est. completion 2027-06-30 1 site Stand-alone
    Prediabetes Other conditions: Males, Females, Sedentary, Metformin
    View official trial listing →
  • Recruiting NCT NCT07141342

    Fast In-Bed Tracking (FIT) System Lifestyle Intervention is a Clinical Trial of a Bed Scale Device. Overweight Wheelchair Users Will Complete a Weight Loss Program, Half Get Scales at Baseline, Half at Month 6 Those Who Receive the Bed Scales at Baseline Are Expected to Have Increased Weight Loss

    Not yet reported Jonathan Pearlman 20 participants Est. completion 2027-07-31 1 site Stand-alone
    Other conditions: Disability Physical, Wheelchair, Obesity; Overweight
    View official trial listing →
  • Recruiting NCT NCT07182526

    Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycystic Ovary Syndrome

    Not yet reported Al-Mustansiriyah University 150 participants Est. completion 2026-05-01 1 site Stand-alone
    Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
    View official trial listing →
  • Recruiting NCT NCT07188740

    Metformin Inhibits DNMT3A Clonal Hematopoiesis in Acute Leukemia

    Not yet reported Institute of Hematology & Blood Diseases Hospital, China 32 participants Est. completion 2029-08-30 1 site Stand-alone
    Other conditions: DNMT3A Gene Mutation
    View official trial listing →
  • Recruiting NCT NCT07193069

    Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning

    Centre Hospitalier de Saint-Denis 50 participants Est. completion 2026-04-11 1 site
    Other conditions: Drug Overdose, Metformin, Dapagliflozin, Lactic Acidosis, Diabetic Ketoacidosis, Intensive Care Units
    View official trial listing →
  • Recruiting NCT NCT07226453

    Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

    Not yet reported University of California, San Francisco 30 participants Est. completion 2030-03-31 10 sites Stand-alone
    Other conditions: Posterior Fossa Ependymal Tumor
    View official trial listing →
  • Recruiting NCT NCT07229651

    Metformin in Parkinson Disease

    Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2027-09-20 1 site
    Other conditions: Parkinson Disease
    View official trial listing →
  • Recruiting NCT NCT07244003

    Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control

    Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 430 participants Est. completion 2028-06-30 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07244575

    Association Between Preoperative Metformin Exposure and Postoperative Nausea and Vomiting in Patients Undergoing General Anesthesia

    Sixth Affiliated Hospital, Sun Yat-sen University 909 participants Est. completion 2033-12-31 1 site
    Other conditions: Postoperative Nausea and Vomiting
    View official trial listing →
  • Recruiting NCT NCT07254572

    Anti-atherosclerotic Efficacy of Selected Antidiabetic Drugs in Patients With Coronary Artery Disease and Pre-diabetes

    Not yet reported National Institute of Cardiology, Warsaw, Poland 300 participants Est. completion 2029-08-01 1 site
    Cardiovascular diseasePrediabetes
    View official trial listing →
  • Recruiting NCT NCT07289399

    Is There a Benefit From Addition of Treadmill Walking to Diet Restriction in Psoriasis Women With PCOS?

    Not yet reported Cairo University 40 participants Est. completion 2026-05-15 1 site Stand-alone
    Other conditions: Psoriasis, Polycystic Ovary Syndrome
    View official trial listing →
  • Recruiting NCT NCT07291297

    Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma

    Not yet reported Wake Forest University Health Sciences 50 participants Est. completion 2033-10 2 sites
    Other conditions: Sarcoma Metastatic, Sarcoma, Soft Tissue
    View official trial listing →
  • Recruiting NCT NCT07293325

    Semaglutide and Tirzepatide for Genetic Aging Delay in Adults With Obesity

    Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 66 participants Est. completion 2027-06-02 1 site
    Other conditions: Adults With Simple Obesity
    View official trial listing →
  • Recruiting NCT NCT07297290

    Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)

    Not yet reported University Of Nigeria Teaching Hospital 220 participants Est. completion 2027-09-30 2 sites Stand-alone
    Other conditions: Obesity and Cardiovascular Risk, Insulin Resistance, Obesity (Body Mass Index >30 kg/m2)
    View official trial listing →
  • Recruiting NCT NCT07300293

    Lactic Acidosis and Prior Metformin Treatment

    University Hospital, Strasbourg, France 100 participants Est. completion 2026-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07309094

    Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD

    Cardenal Herrera University 250 participants Est. completion 2028-12-31 1 site
    Chronic kidney diseaseType 2 diabetes Other conditions: Obesity
    View official trial listing →
  • Recruiting NCT NCT07331389

    A Drug-Drug Interaction Study of HDM1002 and Metformin, Empagliflozin, Midazolam, Valsartan, and Warfarin

    Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 111 participants Est. completion 2026-06-13 1 site Stand-alone
    Other conditions: Overweight Subject, Healthy Subjects
    View official trial listing →
  • Recruiting NCT NCT07339722

    A Study of LY4515100 in Healthy Participants

    Not yet reported Eli Lilly and Company 123 participants Est. completion 2027-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Recruiting NCT NCT07366944

    PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes

    Not yet reported Cairo University 40 participants Est. completion 2026-06-05 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Dry Eye, Obesity
    View official trial listing →
  • Recruiting NCT NCT07372625

    A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.

    Not yet reported PMV Pharmaceuticals, Inc 14 participants Est. completion 2028-01 5 sites Stand-alone
    Other conditions: TP53 Y220C Mutation, Advanced Solid Tumors
    View official trial listing →
  • Recruiting NCT NCT07374328

    Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes Mellitus

    Not yet reported, Not yet reported Second Affiliated Hospital of Guangzhou Medical University 240 participants Est. completion 2026-08-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07379333

    A Study to Evaluate Efficacy and Safety of HM11260C in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin

    Not yet reported Hanmi Pharmaceutical Company Limited 118 participants Est. completion 2028-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07387900

    Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia

    Not yet reported Cairo University 34 participants Est. completion 2027-10 1 site Stand-alone
    Other conditions: Oral Leukoplakia
    View official trial listing →
  • Recruiting NCT NCT07395960

    The Efficacy and Safety of Metformin Intervention in Elderly Overweight or Obesity With Mild Cognitive Impairment

    Not yet reported, Not yet reported Fudan University 54 participants Est. completion 2026-09-30 1 site Stand-alone
    Other conditions: Mild Cognitive Impairment, Overweight or Obesity, Elderly
    View official trial listing →
  • Recruiting NCT NCT07442006

    Glycemic Variability of Combination Therapies in T2DM

    Not yet reported JW Pharmaceutical 178 participants Est. completion 2027-03-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07446400

    A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together

    Not yet reported Otsuka Pharmaceutical Development & Commercialization, Inc. 48 participants Est. completion 2026-11-07 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Recruiting NCT NCT07446985

    Is There a Benefit From Addition of Physical Exercise to Diet Restriction/Limitation in PCOS Women With Asthma?

    Not yet reported Cairo University 40 participants Est. completion 2026-07-15 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Asthma
    View official trial listing →
  • Recruiting NCT NCT07497568

    Effect of Local Application of 1% Metformin Gel on Implant Stability and Peri-implant Bone Density: A Randomized Controlled Study

    Not yet reported University of Baghdad 34 participants Est. completion 2027-06-01 1 site Stand-alone
    Other conditions: Dental Implant, Stability
    View official trial listing →
  • Recruiting NCT NCT07550816

    Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants

    Not yet reported Beijing QL Biopharmaceutical Co.,Ltd 60 participants Est. completion 2027-03-26 1 site Stand-alone
    Other conditions: Overweight,Obesity
    View official trial listing →
  • Recruiting NCT NCT07588932

    Relying on Pharmacotherapy to Improve Motor Gains in Chronic Stroke Survivors

    Not yet reported Spaulding Rehabilitation Hospital 50 participants Est. completion 2028-12-31 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Recruiting NCT NCT07591246

    Efficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid Hypofunction

    Not yet reported Cairo University 40 participants Est. completion 2026-12-30 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Non-Alcoholic Fatty Pancreatic Disease, Subclinical hypothyroïdism
    View official trial listing →
  • Recruiting NCT NCT07630779

    Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients

    Not yet reported Beni-Suef University 180 participants Est. completion 2026-12 1 site Stand-alone
    Other conditions: Poly Cystic Ovary Syndrome
    View official trial listing →
  • Recruiting NCT NCT07645001

    Therapeutic Synergy of Probiotic Augmented Conventional Antidiabetic Pharmacotherapy in Gestational Diabetes Mellitus

    Not yet reported Riphah International University 200 participants Est. completion 2027-06 1 site Stand-alone
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Recruiting NCT NCT07653477

    Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Metformin ± Sulfonylurea/SGLT2 Inhibitor Therapy (UNIGUIDE-2)

    Not yet reported The United Bio-Technology (Hengqin) Co., Ltd. 956 participants Est. completion 2028-02-29 1 site
    Type 2 diabetes
    View official trial listing →
  • Recruiting NCT NCT07654179

    Metformin as Adjunct Therapy in Depression-obesity Comorbidity: Clinical and Genetic Evaluation

    Not yet reported Riphah International University 200 participants Est. completion 2027-06-11 2 sites Stand-alone
    Other conditions: Depression, Depressive Disorder, Overweight or Obesity, Depressive Symptoms
    View official trial listing →
  • Recruiting NCT NCT07693452

    Metformin in Pseudomyxoma Peritonei Secondary to Appendiceal Mucinous Neoplasms

    Not yet reported University of California, Irvine 15 participants Est. completion 2029-07 1 site Stand-alone
    Other conditions: Appendiceal Mucinous Neoplasm, Pseudomyxoma Peritonei
    View official trial listing →
  • Recruiting NCT NCT07724132

    An Evaluation of Treatments for Sustained Clinical Response (18 Months) in Symptomatic Alzheimer's Disease

    Not yet reported University College, London 1200 participants Est. completion 2031-03 2 sites
    Other conditions: Alzheimer's Disease (AD), Mild Cognitive Impairment Due to Alzheimer's Disease, Alzheimer Disease Dementia
    View official trial listing →
  • Recruiting NCT NCT07760883

    Metformin Effects According to SLC16A11 Carrier Status

    Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 154 participants Est. completion 2027-12 1 site
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Recruiting NCT NCT07771010

    The Effect of Empagliflozin and Metformin on Oxidative Capacity and Microvascular Reactivity of Skeletal Muscle in Patients With Type 2 Diabetes Mellitus

    Not yet reported University Medical Centre Ljubljana 54 participants Est. completion 2028-07-31 1 site
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Recruiting NCT NCT07785934

    Phase I Drug-Drug Interaction Study of UBT251 Injection in Participants With Overweight or Obesity

    Not yet reported The United Bio-Technology (Hengqin) Co., Ltd. 48 participants Est. completion 2026-12 1 site Stand-alone
    Other conditions: Drug Drug Interaction (DDI), Pharmacokinetics and Pharmacodynamics
    View official trial listing →
  • Recruiting NCT NCT07802561

    Comparison of Metformin Versus Glyburide for Blood Sugar Control in Women With Gestational Diabetes

    Not yet reported Nishtar Medical University 92 participants Est. completion 2026-10-17 1 site
    Other conditions: Gestational Diabetes Mellitus (GDM)
    View official trial listing →
  • Recruiting NCT NCT07817056

    Risk-Stratified Management of Inavolisib-Induced Hyperglycemia and Patient Adherence

    Tianjin Medical University Cancer Institute and Hospital 100 participants Est. completion 2028-10-31 1 site
    Other conditions: Breast Cancer, Hyperglycemia
    View official trial listing →
  • Recruiting NCT NCT07817069

    Effects of Nitraria Retusa Infusion on Clozapine-induced Metabolic Side Effects

    Not yet reported Faculty of Medicine, Sousse 30 participants Est. completion 2028-12 1 site Stand-alone
    Other conditions: Treatment Resistant Schizophrenia, Obesity & Overweight, Abdominal Obesity
    View official trial listing →
  • Completed NCT NCT00000620

    Action to Control Cardiovascular Risk in Diabetes (ACCORD)

    Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 10251 participants Est. completion 2012-12 7 sites
    Cardiovascular diseaseType 2 diabetes Other conditions: Atherosclerosis, Hypercholesterolemia, Hypertension, Diabetes Mellitus, Coronary Disease
    View official trial listing →
  • Completed NCT NCT00004992

    Diabetes Prevention Program

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 3234 participants Est. completion 2001-04 1 site
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent, Glucose Intolerance
    View official trial listing →
  • Completed NCT NCT00005104

    Randomized Study of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Women With Polycystic Ovary Syndrome

    Not yet reported National Center for Research Resources (NCRR) 99 participants 6 sites
    Other conditions: Polycystic Ovary Syndrome, Hyperinsulinism
    View official trial listing →
  • Completed NCT NCT00005654

    Randomized Study of the Effect of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Obese Women With Polycystic Ovary Syndrome

    Not yet reported National Center for Research Resources (NCRR) 88 participants
    Other conditions: Hyperinsulinism, Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00005669

    Metformin to Treat Obesity in Children With Insulin Resistance

    Not yet reported Jack Yanovski, M.D. 100 participants Est. completion 2011-05 1 site
    Other conditions: Hyperinsulinemia, Obesity
    View official trial listing →
  • Completed NCT NCT00015626

    A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)

    Not yet reported National Center for Research Resources (NCRR) 300 participants 1 site
    Other conditions: Insulin Resistance, Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00015691

    Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalities

    Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 105 participants 34 sites
    Other conditions: HIV Infections, Lipodystrophy, Hyperinsulinemia
    View official trial listing →
  • Completed NCT NCT00018616

    Improving Compliance With Metformin

    Not yet reported US Department of Veterans Affairs 79 participants Est. completion 2005-01 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00032487

    Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)

    Not yet reported VA Office of Research and Development 1791 participants Est. completion 2008-05-30 21 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00035542

    A Research Study to Determine the Safety and Efficacy of Glucovance Compared to Metformin and Glyburide in Children and Adolescents With Type 2 Diabetes.

    Not yet reported Bristol-Myers Squibb Est. completion 2003-10 50 sites
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00035568

    A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes

    Not yet reported Bristol-Myers Squibb Est. completion 2003-06 9 sites
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00035984

    Evaluation of the Effect on Glucose Control of AC2993 in Patients With Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 734 participants Est. completion 2003-08 100 sites
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00038727

    Diabetes Prevention Program Outcomes Study

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2779 participants Est. completion 2022-04-30 1 site
    Other conditions: Diabetes Mellitus, Cancer, CVD
    View official trial listing →
  • Completed NCT NCT00039013

    Evaluation of the Effect on Glucose Control of AC2993 in Patients With Type 2 Diabetes Mellitus Treated With Metformin

    Not yet reported AstraZeneca 336 participants Est. completion 2003-06 129 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00044447

    Evaluate the Role of Adding Amaryl to Non-Insulin Dependent Diabetes Mellitus Patients Unresponsive to Maximum Dose Metformin & Thiazolidinedione

    Not yet reported Sanofi 170 participants Est. completion 2002-09 1 site
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00044668

    Evaluation of the Effect on Glucose Control and Safety of AC2993 in Patients With Type 2 Diabetes Treated With Metformin, Sulfonylurea, or Metformin and Sulfonylurea Combination

    Not yet reported AstraZeneca 155 participants Est. completion 2005-09 3 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00046462

    Determine Whether Glycemic Control is Different Between Lantus & a 3rd Oral Agent When Failure With Other Treatment

    Not yet reported Sanofi 240 participants Est. completion 2004-12 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00067951

    A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics

    Not yet reported GlaxoSmithKline 190 participants Est. completion 2004-11-30 94 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00068861

    Treatment of Infertility in Women With Polycystic Ovary Syndrome

    Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 678 participants Est. completion 2006-02 11 sites
    Other conditions: Polycystic Ovary Syndrome, Infertility, Pregnancy
    View official trial listing →
  • Completed NCT NCT00069836

    Study Of AVANDAMET® With Or Without Insulin In Type II Diabetes Mellitus Patients. AVANDAMET® is a Registered Trademark of the GSK Group of Companies.

    Not yet reported GlaxoSmithKline 272 participants Est. completion 2004-11 93 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00081328

    Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 699 participants Est. completion 2014-02 16 sites Stand-alone
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Completed NCT NCT00082407

    Exenatide Compared With Twice-Daily Biphasic Insulin Aspart in Patients With Type 2 Diabetes Using Sulfonylurea and Metformin

    Not yet reported AstraZeneca 505 participants Est. completion 2008-07 69 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00086502

    Pioglitazone Add-on Study in Patients With Type 2 Diabetes Mellitus

    Not yet reported Merck Sharp & Dohme LLC 353 participants Est. completion 2005-11
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00086515

    Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-020)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 701 participants Est. completion 2007-02-02 Stand-alone
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Completed NCT NCT00094770

    An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (0431-024)

    Not yet reported Merck Sharp & Dohme LLC 1172 participants Est. completion 2007-05
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00095030

    Study Comparing Muraglitazar With Glimepiride in Type 2 Diabetics Who Are Not Controlled With Metformin Alone

    Not yet reported Bristol-Myers Squibb 1752 participants Est. completion 2006-03 206 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00097279

    Comparison of Biphasic Insulin Aspart 70/30 With Anti-Diabetic Drugs in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 230 participants Est. completion 2005-08 73 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00097500

    Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 69 participants Est. completion 2009-12 3 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00097877

    Comparison of Biphasic Insulin Aspart 70/30 Versus Insulin Glargine in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 293 participants Est. completion 2006-11 73 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00099320

    Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Thiazolidinediones or Thiazolidinediones and Metformin

    Not yet reported AstraZeneca 182 participants Est. completion 2005-08 51 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00099619

    Comparing Exenatide and Insulin Glargine in Type 2 Diabetes Patients for Whom Insulin is the Next Appropriate Therapy

    Not yet reported AstraZeneca 138 participants Est. completion 2005-08 26 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00099866

    Efficacy and Safety of Vildagliptin Compared to Metformin in Drug Naive Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 570 participants Est. completion 2005-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00099892

    Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 544 participants Est. completion 2005-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00102466

    Vildagliptin Compared to Gliclazide in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 1007 participants Est. completion 2009-01 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00103857

    MK0431 (Sitagliptin) and Metformin Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-036)

    Not yet reported Merck Sharp & Dohme LLC 1208 participants Est. completion 2008-02-21 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00105066

    The Effects of Metformin on Blood Vessel Structure and Function

    Not yet reported National Institute on Aging (NIA) 77 participants Est. completion 2008-05 1 site Stand-alone
    Other conditions: Obesity, Hypertension, Hypercholesterolemia, Hyperglycemia
    View official trial listing →
  • Completed NCT NCT00106340

    Vildagliptin Compared to Glimepiride in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 3118 participants Est. completion 2008-05-20 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00106704

    Sulfonylurea Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-035)

    Not yet reported Merck Sharp & Dohme LLC 441 participants Est. completion 2007-01
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00108615

    Effects of Insulin Sensitizers in Subjects With Impaired Glucose Tolerance

    Not yet reported US Department of Veterans Affairs 48 participants Est. completion 2007-12 1 site Stand-alone
    Other conditions: Glucose Metabolism Disorders, Diabetes
    View official trial listing →
  • Completed NCT NCT00110851

    Safety and Efficacy Study of PN2034 in Type 2 Diabetes Patients on Concomitant Rosiglitazone and Metformin (or Avandamet)

    Not yet reported Wellstat Therapeutics 90 participants Est. completion 2007-08 20 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00111631

    A Study of DPP-IV Inhibitor in Patients With Type 2 Diabetes

    Not yet reported Hoffmann-La Roche 218 participants Est. completion 2006-10 37 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00118937

    Effect of Metformin in Patients With Type-1 Diabetes With Inadequate Glycaemic Control by Insulin and Diet

    Not yet reported Steno Diabetes Center Copenhagen 100 participants Est. completion 2006-08
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT00118950

    Effect of Metformin Versus Repaglinide Treatment in Non-Obese Type 2 Diabetic Patients Uncontrolled by Diet

    Not yet reported Steno Diabetes Center Copenhagen 100 participants Est. completion 2003-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00118963

    Effect of Repaglinide Versus Metformin Treatment in Non-Obese Patients With Type-2-Diabetes

    Not yet reported Steno Diabetes Center Copenhagen 102 participants Est. completion 2006-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00121641

    Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

    Not yet reported AstraZeneca 1035 participants Est. completion 2010-02 134 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00121667

    Study Assessing Saxagliptin Treatment In Type 2 Diabetic Subjects Who Are Not Controlled With Metformin Alone

    Not yet reported AstraZeneca 1462 participants Est. completion 2010-02 152 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00121966

    South Danish Diabetes Study: Evaluation of the Antidiabetic Treatment of Type 2 Diabetes Mellitus

    Not yet reported Odense University Hospital 400 participants Est. completion 2007-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00123110

    Insulin Resistance and Testosterone in Women

    Not yet reported University of Pennsylvania 35 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Insulin Resistance, Postmenopause
    View official trial listing →
  • Completed NCT NCT00131664

    Avandia™ + Amaryl™ or Avandamet™ Compared With Metformin (AVALANCHE™ Study)

    Not yet reported Canadian Heart Research Centre 391 participants Est. completion 2008-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00133718

    A 2 Year Trial of Patients With Type 2 Diabetes Focusing on Cardiovascular Diagnostics and Metabolic Control

    Not yet reported Asker & Baerum Hospital 120 participants Est. completion 2012-05-29 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00134290

    The Effects of Calorie Restriction With or Without Metformin on Weight and Insulin Resistance

    Not yet reported University Hospital, Ghent 48 participants Est. completion 2004-05 1 site
    Other conditions: Body Weight, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT00134303

    Trial Comparing Metformin Versus Placebo in Non Alcoholic Steatohepatitis (NASH) Patients Receiving Bariatric Surgery for Obesity

    Not yet reported University Hospital, Ghent 65 participants Est. completion 2006-03-31 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT00135096

    Insulin Glulisine Administered Pre-meal Versus Post-meal in Adult Subjects With Type 2 Diabetes Mellitus Receiving Insulin Glargine as Basal Insulin

    Not yet reported Sanofi 345 participants Est. completion 2007-07 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00135330

    An Evaluation of Exenatide and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 137 participants Est. completion 2008-07 19 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00138515

    Extension to a Study on the Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Novartis 418 participants Est. completion 2006-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00138567

    Extension to a Study on the Efficacy and Safety of Vildagliptin Compared to Metformin in Drug Naive Patients With Type 2 Diabetes

    Not yet reported Novartis 530 participants Est. completion 2006-08 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00145379

    The Effect of Metformin in Overweight Patients With Dysregulated Type 1 Diabetes Mellitus

    Not yet reported Odense University Hospital 42 participants Est. completion 2006-06 1 site Stand-alone
    Other conditions: Type 1 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00147719

    WelChol® With Metformin in Treating Patients With Type 2 Diabetes

    Not yet reported Daiichi Sankyo 300 participants Est. completion 2006-07 48 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00147836

    Evaluation of the Effects of Different Interventions on Glycemic Control in Newly-Diagnosed Type 2 Diabetic Patients

    Not yet reported Sun Yat-sen University 436 participants Est. completion 2007-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00151411

    Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS)

    Not yet reported Milton S. Hershey Medical Center 114 participants Est. completion 2008-03 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00155545

    Influence of Leg Length Discrepancy on the Spinal Shape and Biomechanics in Functional and Idiopathic Scoliosis Patients

    Not yet reported National Taiwan University Hospital 30 participants Est. completion 2008-09 1 site
    Other conditions: Leg Length Discrepancy, Scoliosis
    View official trial listing →
  • Completed NCT NCT00156897

    Efficacy and Safety of ATL-962 in Obese Diabetics

    Not yet reported Alizyme 600 participants Est. completion 2005-10 37 sites
    Other conditions: Non-Insulin-Dependent Diabetes Mellitus, Obesity
    View official trial listing →
  • Terminated NCT NCT00159211

    Abdominal Adipose Tissue Distribution in Type 2 Diabetic Patients Treated During 6 Months With Pioglitazone or Insulin

    Not yet reported Assistance Publique - Hôpitaux de Paris 28 participants Est. completion 2007-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00159575

    Metformin in Assisted Reproduction-MET-AR-study

    Not yet reported Norwegian University of Science and Technology 150 participants Est. completion 2010-04 2 sites Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00162240

    PPAR - Combination With Metformin

    Not yet reported Bristol-Myers Squibb 534 participants Est. completion 2004-05 203 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT00169624

    Peripheral and Coronary Endothelial Dysfunction In Type 2diabetic Patients- Role of Metformin

    Not yet reported Hospices Civils de Lyon 30 participants 1 site
    Other conditions: Coronary and Peripheral Endothelial Dysfunction
    View official trial listing →
  • Completed NCT NCT00174642

    Opposing Step-by-step Insulin Reinforcement to Intensified Strategy

    Not yet reported Sanofi 811 participants 18 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00182494

    Diabetes Prevention Program in Schizophrenia [DPPS]

    Not yet reported Hamilton Health Sciences Corporation 200 participants Est. completion 2009-01 1 site
    Other conditions: Diabetes Mellitus, Schizophrenia
    View official trial listing →
  • Completed NCT NCT00184574

    Comparison of Biphasic Insulin Aspart 70/30, 50/50, and 30/70 in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 603 participants Est. completion 2006-03 108 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00184626

    Comparison of Insulin Glargine Versus Biphasic Insulin Aspart 30/70 or Biphasic Insulin Aspart 30/70 in Combination With Metformin in Subjects With Type 2 Diabetes.

    Not yet reported Novo Nordisk A/S 97 participants Est. completion 2005-10-24 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00187681

    Organic Cation Transporter 1 (OCT1), on Response to Metformin in Healthy Subjects

    Not yet reported University of California, San Francisco 20 participants Est. completion 2008-03 1 site Stand-alone
    Other conditions: Other Conditions That May Be A Focus of Clinical Attention
    View official trial listing →
  • Completed NCT NCT00187720

    Genetic Basis for Variation in the Renal Elimination of Metformin

    Not yet reported University of California, San Francisco 23 participants Est. completion 2008-04 1 site Stand-alone
    Other conditions: Other Conditions That May Be A Focus of Clinical Attention
    View official trial listing →
  • Completed NCT NCT00187798

    Impact of Genetics on Metformin Pharmacokinetics

    Not yet reported University of California, San Francisco 24 participants Est. completion 2007-07 1 site
    Other conditions: Other Conditions That May Be A Focus of Clinical Attention
    View official trial listing →
  • Completed NCT NCT00191464

    Long-Term Effects of Insulin Plus Metformin Regimens on the Overall and Postprandial Glycemic Control of Patients With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 320 participants Est. completion 2005-09 7 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00203632

    Glitazones and Endothelial Function (GATE)

    Not yet reported University of Calgary 40 participants Est. completion 2007-10 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT00209482

    Glaser Obesity Study

    Not yet reported, Not yet reported Glaser Pediatric Research Network 76 participants Est. completion 2007-11 5 sites
    Other conditions: Obesity
    View official trial listing →
  • Terminated NCT NCT00214591

    GALLANT 5 Tesaglitazar Versus Metformin

    Not yet reported AstraZeneca 580 participants Est. completion 2006-12 130 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00219440

    A Portion-controlled Diet Will Prevent Weight Gain in Diabetics Treated With ACTOS

    Not yet reported Pennington Biomedical Research Center 60 participants Est. completion 2006-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00231647

    A Study on Efficacy and Safety of Topiramate OROS Controlled-Release in Obese, Type 2 Diabetic Subjects Managed With Diet or Metformin

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 113 participants Est. completion 2004-10
    Type 2 diabetes Other conditions: Obesity, Diabetes Mellitus, Adult-Onset
    View official trial listing →
  • Completed NCT NCT00231660

    A Study of the Efficacy and Safety of Topiramate in the Treatment fo Obese, Type 2 Diabetic Patients Treated With Metformin

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 211 participants Est. completion 2002-06
    Type 2 diabetes Other conditions: Obesity, Diabetes Mellitus, Adult-Onset
    View official trial listing →
  • Completed NCT NCT00237237

    Vildagliptin Compared to Pioglitazone in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Novartis 588 participants 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00240370

    A Study to Evaluate Combining Metformin With Muraglitazar or Pioglitazone in Type 2 Diabetics

    Not yet reported Bristol-Myers Squibb 1159 participants 85 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00241423

    Effect of Exenatide on 24-Hour Blood Glucose Profile Compared With Placebo in Patients With Type 2 Diabetes

    Not yet reported AstraZeneca 30 participants Est. completion 2007-06 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00241605

    AVANDAMET Versus Metformin For Type 2 Diabetes Mellitus

    Not yet reported GlaxoSmithKline 600 participants Est. completion 2005-12-16 91 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00247117

    Metformin in Patients With Non-Alcoholic Fatty Liver Disease (NAFLD)

    Not yet reported Kaplan Medical Center 15 participants Est. completion 2005-08 1 site
    Other conditions: Liver Diseases
    View official trial listing →
  • Terminated NCT NCT00251953

    GALLANT 8 Tesaglitazar Add-on to Metformin

    Not yet reported AstraZeneca 555 participants Est. completion 2006-03 107 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00263276

    A Trial of BMS-512148 in Patients With Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 389 participants Est. completion 2007-02 144 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00263965

    ARAMIS: Actions of tesaglitazaR on fAt Metabolism and Insulin Sensitivity

    Not yet reported AstraZeneca 105 participants Est. completion 2006-07 3 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00265746

    Prevention of Diabetes Mellitus Development in Women Who Had Already Experienced A Gestational Diabetes

    Not yet reported Medical University of Lodz
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00266253

    A Study of GK Activator (2) in Patients With Type 2 Diabetes Mellitus Treated With a Stable Dose of Metformin

    Not yet reported Hoffmann-La Roche 220 participants Est. completion 2007-03 47 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT00268476

    Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy

    Not yet reported, Not yet reported Medical Research Council 11992 participants Est. completion 2030-12 120 sites Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00269061

    Study In Patients With Type 2 Diabetes Who Are Taking Metformin And Sulfonylurea, Metformin And Insulin, Or Insulin

    Not yet reported GlaxoSmithKline 32 participants 1 site
    Other conditions: Non-Insulin-Dependent Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00272064

    ELEONOR STUDY: Insulin Glulisine in Type 2 Diabetes Mellitus.

    Not yet reported Sanofi 352 participants Est. completion 2008-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00279045

    Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide

    Not yet reported GlaxoSmithKline 4426 participants Est. completion 2006-06-19 490 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00279240

    Life Style Modifications Prevents Type 2 Diabetes in Asian Indians

    Not yet reported M.V. Hospital for Diabetes Est. completion 2004-12 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00282451

    Effect of Biphasic Insulin Compared to Biphasic Insulin Combined With Insulin Aspart, With or Without Metformin in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 79 participants Est. completion 2006-08 4 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT00282945

    Beta Cell Function Tests Over Time In Patients With T2dm Randomized To Metformin Or Rosiglitazone

    Not yet reported Pfizer 29 participants Est. completion 2007-10 2 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00283049

    Insulin Glargine Injection Treatment in Place of Thiazolidinedione (TZD), Sulfonylurea, or Metformin in Triple Agent Therapy for Type 2 Diabetes Mellitus (T2DM) Adult Subjects With Unsatisfactory Control

    Not yet reported Sanofi 390 participants Est. completion 2008-11 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00283816

    Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy

    Not yet reported University of Rochester 36 participants Est. completion 2008-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00286442

    Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus

    Not yet reported Takeda 527 participants Est. completion 2007-06 56 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00290940

    Evaluation of Glucose Lowering Effect, Safety and Tolerability of CS-917

    Not yet reported Daiichi Sankyo 400 participants Est. completion 2007-04 66 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00295633

    A Study Assessing Saxagliptin Treatment in Type 2 Diabetic Subjects Who Are Not Controlled With TZD Therapy Alone

    Not yet reported AstraZeneca 565 participants Est. completion 2008-10 133 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00299871

    Dose Ranging Study of the GLP-1 Agonist AVE0010 in Metformin-Treated Subjects With Type 2 Diabetes Mellitus

    Not yet reported Sanofi 542 participants Est. completion 2007-08 7 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00303537

    Metformin in Non-Alcoholic Fatty Liver Disease

    Not yet reported, Not yet reported University Hospital, Aker 90 participants Est. completion 2008-06 4 sites
    Other conditions: Fatty Liver
    View official trial listing →
  • Completed NCT NCT00308373

    Effects of Fats on Blood Glucose in People With and Without Type 2 Diabetes Mellitus

    Not yet reported Mayo Clinic 73 participants Est. completion 2005-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00309608

    Efficacy and Safety of BI 1356 BS (Linagliptin) in Combination With Metformin in Patients With type2 Diabetes

    Not yet reported Boehringer Ingelheim 333 participants 48 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00313001

    Effects of Biphasic Insulin Aspart 70/30 vs. Exenatide in Type 2 Diabetes Patients Not Reaching Blood Glucose Targets on Metformin and a Sulfonylurea.

    Not yet reported Novo Nordisk A/S 373 participants Est. completion 2007-07 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00313313

    A Study of Saxagliptin in Subjects With Type 2 Diabetes Who Have Inadequate Blood Sugar Control With Sulfonylureas

    Not yet reported AstraZeneca 768 participants Est. completion 2008-09 115 sites Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00316082

    Study of BMS-477118 as Monotherapy With Titration in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

    Not yet reported AstraZeneca 365 participants Est. completion 2008-11 74 sites Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT00317928

    Efficacy of Metformin in PCOS: Metabolic and Hormonal Factors

    Not yet reported Aarhus University Hospital Skejby 50 participants Est. completion 2004-09
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00318461

    To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together

    Not yet reported Novo Nordisk A/S 1091 participants Est. completion 2008-11 190 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00318656

    24-Hour Glycemia: Rosiglitazone Versus Glimepiride In Type 2 Diabetes

    Not yet reported GlaxoSmithKline 23 participants Est. completion 2007-10
    Other conditions: Non-Insulin-Dependent Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT00319293

    Efficacy of Metformin in Lean Women With Polycystic Ovary Syndrome

    Not yet reported Aarhus University Hospital Skejby 20 participants
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00324363

    Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Metformin or Sulfonylureas and Metformin

    Not yet reported AstraZeneca 466 participants Est. completion 2007-04 14 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00325910

    Patients With Heart Failure ANd Type 2 Diabetes Treated With Placebo Or Metformin (PHANTOM) Pilot Study

    Not yet reported University of Alberta 100 participants Est. completion 2007-05 2 sites
    Type 2 diabetesHeart failure
    View official trial listing →
  • Completed NCT NCT00327015

    A Phase 3 Study of BMS-477118 in Combination With Metformin in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

    Not yet reported AstraZeneca 1306 participants Est. completion 2008-12 211 sites Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00328172

    Efficacy and Safety of 3 Doses of BI1356 (Linagliptin) in Type 2 Diabetes Patients

    Not yet reported Boehringer Ingelheim 302 participants 71 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00331851

    Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 584 participants Est. completion 2007-04 116 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT00332085

    Pilot Trial of Chromium-Metformin Combination in Type 2 Diabetes

    Not yet reported Bastyr University 40 participants Est. completion 2007-03 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00332488

    Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents in Subjects With Type 2 Diabetes

    Not yet reported Mannkind Corporation 547 participants 120 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00333151

    Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 576 participants Est. completion 2007-08 89 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT00343395

    Rosiglitazone and Metformin: Outcomes Trial in Nondiabetic Patients With Stable Coronary Syndromes (Romance) Pilot Study

    Not yet reported Intermountain Health Care, Inc. 200 participants Est. completion 2008-01 1 site
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00344851

    Exenatide and Metformin Therapy in Overweight Women With PCOS

    Not yet reported Metabolic Center of Louisiana Research Foundation 60 participants Est. completion 2007-06 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00347100

    Insulin Glargine in Type 2 Diabetic Patients

    Not yet reported Sanofi 387 participants 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00348712

    Efficacy and Safety of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 301 participants Est. completion 2008-03-05 74 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00348725

    Acceptability of a Fixed Combination of Fenofibrate and Metformin

    Not yet reported Solvay Pharmaceuticals 69 participants 25 sites
    Other conditions: Dyslipidemia/Glucose Metabolism Disorder
    View official trial listing →
  • Completed NCT NCT00349128

    Fenofibrate in Dyslipidemia and Metformin-Controlled Diabetes

    Not yet reported, Not yet reported Solvay Pharmaceuticals 382 participants 51 sites
    Other conditions: Dyslipidemia/Glucose Metabolism Disorder
    View official trial listing →
  • Completed NCT NCT00350779

    Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)

    Not yet reported Merck Sharp & Dohme LLC 262 participants Est. completion 2008-06-11
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00351884

    Efficacy of Vildagliptin 100 MG as Compared to Placebo as Add-on to Metformin in Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 370 participants 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00353691

    Glimepiride vs Metformin as Monotherapy in Pediatric Subjects With Type 2 Diabetes Mellitus

    Not yet reported Sanofi 100 participants Est. completion 2004-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00357370

    A Pilot Study of BMS-512148 in Subjects With Type 2 Diabetes

    Not yet reported, Not yet reported AstraZeneca 163 participants Est. completion 2008-03 23 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00358124

    Insulin Glargine v Rosiglitazone as add-on Therapy in Patients Failing Sulfonylurea and Metformin Combination Therapy

    Not yet reported Sanofi 220 participants Est. completion 2002-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00359112

    AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes

    Not yet reported GlaxoSmithKline 544 participants 142 sites
    Other conditions: Non-Insulin-Dependent Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00359762

    Exenatide Versus Glimepiride in Patients With Type 2 Diabetes

    Not yet reported AstraZeneca 1029 participants Est. completion 2011-03 114 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00360698

    Insulin Glulisine in Type 2 Diabetic Patients

    Not yet reported Sanofi 106 participants Est. completion 2008-08 3 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00361738

    Dose-Ranging Study Evaluating AVE2268 in Patients With Type 2 Diabetes Not Adequately Controlled by a Metformin Treatment

    Not yet reported Sanofi 317 participants Est. completion 2008-01 11 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00361868

    Fenofibrate and Metformin Fixed Combination vs Rosiglitazone - FAME ROSI

    Not yet reported Solvay Pharmaceuticals 88 participants Est. completion 2007-12 70 sites Stand-alone
    Other conditions: Dyslipidemia, Glucose Metabolism Disorder
    View official trial listing →
  • Completed NCT NCT00362323

    Fenofibrate and Metformin Fixed Combination vs Metformin - FAME METFO

    Not yet reported Solvay Pharmaceuticals 482 participants Est. completion 2009-03 70 sites Stand-alone
    Other conditions: Dyslipidemia/Glucose Metabolism Disorder
    View official trial listing →
  • Completed NCT NCT00363948

    Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus

    Not yet reported Ono Pharmaceutical Co., Ltd. 188 participants 8 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00366301

    The LANCET Trial: A Trial of Long-acting Insulin Injection to Reduce C-reactive Protein in Patients With Type 2 Diabetes

    Not yet reported Brigham and Women's Hospital 500 participants Est. completion 2009-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00367055

    Rosiglitazone-Metformin Combination Versus Metformin-Sulfonylurea Combination On Beta-Cell Function In Type 2 Diabetes

    Not yet reported GlaxoSmithKline 84 participants Est. completion 2008-10
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00370617

    Pegylated-Interferon and Ribavirin Plus Metformin in the Treatment of Chronic HCV Infection and Insulin Resistance

    Not yet reported University of Turin, Italy 200 participants Est. completion 2009-01 1 site
    Other conditions: Chronic Hepatitis C, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT00371306

    Comparison of Glucovance to Insulin for Diabetes During Pregnancy

    Not yet reported Regional Obstetrical Consultants 200 participants Est. completion 2008-09 1 site
    Type 2 diabetes Other conditions: Gestational Diabetes, Pregnancy
    View official trial listing →
  • Completed NCT NCT00373178

    Metabolic Effects of Treatment in Patients With Recently Diagnosed Type 2 Diabetes

    Not yet reported Aristotle University Of Thessaloniki 100 participants Est. completion 2008-06 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00374907

    A Study Assessing Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise

    Not yet reported AstraZeneca 156 participants Est. completion 2009-12 3 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00375388

    The HOME Trial: Hyperinsulinaemia: the Outcome of Its Metabolic Effects, a Randomized Controlled Trial

    Not yet reported Bethesda General Hospital, Hoogeveen 400 participants Est. completion 2002-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00376038

    Drug Interactions From Simultaneous Administration Of Metformin And GSK189075 To Subjects With Type 2 Diabetes

    Not yet reported GlaxoSmithKline 13 participants Est. completion 2006-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00378729

    Surgical Ovarian Drilling Versus Hormonal Treatment for Infertility Associated to PolyCystic Ovaries Syndrome (PCOS)

    Not yet reported Assistance Publique - Hôpitaux de Paris 252 participants Est. completion 2011-10 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00379769

    RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes

    Not yet reported GlaxoSmithKline 4447 participants Est. completion 2008-12 446 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00382096

    Efficacy of Fixed Combination Therapy of Vildagliptin and Metformin Compared to the Individual Monotherapy Components in Drug Naive Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 1179 participants Est. completion 2008-06-03 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00383578

    Efficacy and Safety of Vildagliptin Compared to Metformin in Elderly Drug Naive Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 335 participants 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00384215

    Insulin Glargine [rDNA Origin] Injection vs Pioglitazone as add-on Therapy in Patients Failing Monotherapy With Sulfonylurea or Metformin

    Not yet reported Sanofi 352 participants Est. completion 2005-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00386100

    A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin

    Not yet reported GlaxoSmithKline 688 participants Est. completion 2009-09 116 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00390273

    Effect of Metformin on Lactate Metabolism

    Not yet reported, Not yet reported Centre de Recherche en Nutrition Humaine Rhone-Alpe 20 participants Est. completion 2007-10 1 site
    Other conditions: Hyperlactatemia
    View official trial listing →
  • Completed NCT NCT00391261

    An Open-label Trial of Metformin for Weight Control of Pediatric Patients on Antipsychotic Medications.

    Not yet reported Cambridge Health Alliance 11 participants Est. completion 2007-10 1 site
    Other conditions: Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Bipolar Disorder, Autism Spectrum Disorders
    View official trial listing →
  • Completed NCT NCT00396071

    Efficacy and Safety of Vildagliptin Compared to Placebo on the Incretin Effect in Patients With Type 2 Diabetes Treated With Metformin

    Not yet reported Novartis Pharmaceuticals 22 participants 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00396227

    Safety and Efficacy of Vildagliptin vs. Thiazolidinedione as add-on Therapy to Metformin in Patients With Type 2 Diabetes Not Controlled With Metformin Alone

    Not yet reported Novartis Pharmaceuticals 2665 participants 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00396357

    Efficacy/Safety of Vildagliptin and Metformin Combination Therapy in Patients With Type 2 Diabetes Not Well Controlled With Metformin Alone

    Not yet reported Novartis Pharmaceuticals 914 participants 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00396513

    Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial.

    Not yet reported Poznan University of Medical Sciences 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT00396851

    Double Blind Randomized Trial to Compare Gurmar (Gymnema Sylvestre) With Metformin in Type 2 Diabetes

    Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 100 participants 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00399204

    Comparison of Cardiovascular Outcomes of Pioglitazone and Metformin in Type 2 Diabetes Patients

    Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh Est. completion 2012-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00399360

    Lifestyle Modification and Metformin Use in the Treatment of HIV

    Not yet reported Massachusetts General Hospital 50 participants Est. completion 2012-06 1 site
    Metabolic syndrome Other conditions: HIV Infections
    View official trial listing →
  • Completed NCT NCT00399711

    Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 560 participants Est. completion 2007-11 103 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00400231

    The Fenofibrate and Metformin for Atherogenic Dyslipidemia (FAMA) Study

    Not yet reported University of Pennsylvania 124 participants Est. completion 2008-03 1 site
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT00401973

    Assessment of Safety and Efficacy of Therapy for the Prevention of Weight Gain Associated With Olanzapine

    Not yet reported Eli Lilly and Company 199 participants Est. completion 2008-09 15 sites Stand-alone
    Other conditions: Schizophrenia, Schizoaffective Disorders
    View official trial listing →
  • Completed NCT NCT00402909

    Safety and Efficacy of Nateglinide in Patients With Type 2 Diabetes Already Taking Insulin Glargine, Metformin and/or Pioglitazone or Rosiglitazone

    Not yet reported Novartis Pharmaceuticals 28 participants Est. completion 2007-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00413179

    The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women

    Not yet reported 59th Medical Wing 56 participants Est. completion 2003-04 1 site
    Other conditions: Polycystic Ovary Syndrome, Anovulation, Oligoovulation, Infertility, Hyperandrogenism
    View official trial listing →
  • Status unknown NCT NCT00414245

    Metformin for the Treatment of Diabetes in Pregnancy

    Not yet reported Soroka University Medical Center 200 participants 1 site
    Type 2 diabetes Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT00420511

    Beta-Cell Function and Sitagliptin Trial (BEST)

    Not yet reported Samuel Lunenfeld Research Institute, Mount Sinai Hospital 21 participants Est. completion 2009-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00423501

    A Study of a GLP-1 Analogue in Patients With Type 2 Diabetes Treated With Metformin.

    Not yet reported Hoffmann-La Roche 306 participants Est. completion 2007-11 49 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00425009

    Therapeutic Effects of Berberine in Patients With Type 2 Diabetes

    Not yet reported, Not yet reported Shanghai Jiao Tong University School of Medicine 70 participants Est. completion 2004-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00427154

    Effect of Inhaled Pre-prandial Human Insulin on Blood Glucose Control in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 227 participants Est. completion 2008-03-11 103 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00428311

    Effects of Metformin vs Oral Contraceptives on CV Risk Markers in PCOS

    Not yet reported Hospital Universitario Ramon y Cajal 50 participants Est. completion 2006-10 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00432276

    Efficacy of Alogliptin and Pioglitazone in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Takeda 803 participants Est. completion 2009-06 86 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00434954

    Effect of Exenatide Plus Metformin vs. Insulin Aspart Plus Metformin on Glycemic Control and Hypoglycemia in Patients With Type 2 Diabetes

    Not yet reported AstraZeneca 494 participants Est. completion 2009-06 39 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00437333

    Metformin Suspension and Insulin Sensitivity

    Not yet reported University Magna Graecia 30 participants Est. completion 2006-04 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00437554

    Phase III Study for Glimepiride + Metformin Hydrochloride (Amaryl M) Slow Release (SR)

    Not yet reported Handok Inc. 188 participants Est. completion 2007-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00441363

    Efficacy and Safety of Cycloset® Compared With Placebo When Added to Metformin

    Not yet reported VeroScience 66 participants Est. completion 2006-03
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00443755

    Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin Resistance

    Not yet reported Mayo Clinic 28 participants Est. completion 2010-08 1 site
    Type 2 diabetesMetabolic syndrome Other conditions: Insulin Resistance
    View official trial listing →
  • Completed NCT NCT00445627

    Effect of Short-Term Beta-Cell Rest in Adolescents and Young Adults With Type 2 Diabetes Mellitus

    National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 82 participants 1 site
    Type 2 diabetes Other conditions: Obesity, Overweight
    View official trial listing →
  • Completed NCT NCT00449553

    Observational Study to Assess Glycosylated Hemoglobin Changes After 6 Months of Treatment With Pioglitazone.

    Takeda 326 participants Est. completion 2003-09 4 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT00449605

    A Glycemic Control Evaluation of Glimepiride Versus Rimonabant on Top of Metformin in Type 2 Diabetes

    Not yet reported Sanofi 508 participants Est. completion 2009-03 15 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00449930

    Sitagliptin Comparative Study in Patients With Type 2 Diabetes (0431-049)

    Not yet reported Merck Sharp & Dohme LLC 1050 participants Est. completion 2008-07-25
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00451399

    Efficacy of Lifestyle Interventions and Metformin for the Treatment of Antipsychotic-Induced Weight Gain

    Not yet reported Central South University 128 participants Est. completion 2006-12 1 site
    Other conditions: Weight Gain
    View official trial listing →
  • Completed NCT NCT00451568

    Metformin and Oral Contraceptives in PCOS

    Not yet reported Odense University Hospital 90 participants Est. completion 2013-04 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00454233

    A Safety and Efficacy Study With YM543 in Type 2 Diabetes Mellitus Subjects

    Not yet reported Astellas Pharma Inc 97 participants Est. completion 2008-06 6 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00460941

    A Titration Study of a Glucagon-Like Peptide-1 (GLP-1) Analogue in Patients With Type 2 Diabetes Treated With Metformin.

    Not yet reported Hoffmann-La Roche 133 participants Est. completion 2008-01 29 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00461643

    Strategies for Ovulation Induction in Anovulatory Infertile Patients With PCOS

    Not yet reported University Magna Graecia 552 participants 3 sites
    Other conditions: Anovulatory Infertility Related to Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00463502

    The Effect of Metformin Treatment on Thyroid Hormone Metabolism in Euthyroid Patients With Type 2 Diabetes Mellitus

    Not yet reported Haydarpasa Numune State Hospital
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00464594

    Japan Early Diabetes Intervention Study

    Not yet reported Japan Early Diabetes Intervention Study Group 2560 participants 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00466622

    Uterine Artery Blood Flow in Pregnant Women With PCOS Treated With Metformin

    Not yet reported Norwegian University of Science and Technology 48 participants Est. completion 2010-02 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00468039

    A Sub-study to LMF237A2302 to Assess the Effect of 24 Weeks Treatment With Initial Combination of Vildagliptin Plus Metformin

    Not yet reported Novartis 94 participants Est. completion 2008-06-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00469092

    Comparison of Biphasic Insulin Aspart 30 Versus Insulin Glargine Both in Combination With Metformin and Glimepiride in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 480 participants Est. completion 2008-04 69 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT00469586

    Efficacy and Safety of Inhaled Insulin Compared to Metformin and Glimepiride in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 174 participants Est. completion 2008-04-24 59 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00471523

    Treatment of Anovulatory Infertility in PCOS Patients

    Not yet reported University Magna Graecia 80 participants Est. completion 2007-03 1 site
    Other conditions: Infertility, Polycystic Ovary Syndrome, Anovulation
    View official trial listing →
  • Completed NCT NCT00473525

    12 Week Study Of PF-00734200 For The Treatment Of Type 2 Diabetes Mellitus In Subjects Treated With Metformin

    Not yet reported Pfizer 303 participants Est. completion 2008-06 79 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00473876

    Metformin in Insulin Resistant Left Ventricular (LV) Dysfunction (TAYSIDE Trial)

    Not yet reported University of Dundee 62 participants Est. completion 2009-04 1 site
    Heart failure Other conditions: Insulin Resistance
    View official trial listing →
  • Completed NCT NCT00474838

    Study To Evaluate Beta Cell Function and Glycemic Outcome by Intensive Insulin Therapy

    Not yet reported Kyunghee University Medical Center 112 participants Est. completion 2012-12 8 sites
    Type 2 diabetes Other conditions: Pancreatic Beta Cell Function, Glucotoxicity
    View official trial listing →
  • Terminated NCT NCT00479466

    Dose-Range Finding Study for MK0893 (0893-008)

    Not yet reported Merck Sharp & Dohme LLC 342 participants Est. completion 2008-05 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00481429

    Predictive Markers of Glitazone Efficacy in Diabetic Patients - Pilot Study

    Imperial College London Est. completion 2008-01 4 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00481663

    A Study of Different Doses of Sitagliptin (MK-0431) in Participants With Type 2 Diabetes Mellitus (MK-0431-014)

    Not yet reported Merck Sharp & Dohme LLC 555 participants Est. completion 2006-05-14
    Other conditions: Type II Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00482729

    MK0431A Comparative Study in Patients With Type 2 Diabetes (0431A-079)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 1246 participants Est. completion 2009-04-27 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00483392

    Treatment of Hyperglycaemia and Insulin Resistance in HIV Infected Patients

    Not yet reported University Medical Centre Ljubljana 1 site
    Other conditions: Insulin Resistance
    View official trial listing →
  • Completed NCT NCT00484419

    Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin

    Not yet reported Daiichi Sankyo 169 participants Est. completion 2008-04 20 sites
    Type 2 diabetes Other conditions: Hyperlipidemia
    View official trial listing →
  • Completed NCT NCT00486187

    Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study

    Not yet reported Dr. Milan Gupta 103 participants Est. completion 2009-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00490178

    Acceptability Study of a New Fixed Combination of Fenofibrate 80 mg BID and Metformin 1000 mg BID in Type 2 Diabetes and Dyslipidemia

    Not yet reported Solvay Pharmaceuticals 29 participants 3 sites
    Type 2 diabetes Other conditions: Dyslipidemia
    View official trial listing →
  • Completed NCT NCT00491725

    Efficacy and Safety of Repaglinide and Metformin Combination Therapy in Type 2 Diabetes Failing on Oral Anti-diabetic Drugs

    Not yet reported Novo Nordisk A/S 187 participants Est. completion 2006-06 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00494312

    Safety Study of Pioglitazone Compared To Glyburide on Liver Function

    Not yet reported Takeda 2120 participants Est. completion 2005-06
    Other conditions: Diabetes Mellitus, Liver
    View official trial listing →
  • Terminated NCT NCT00494663

    A Phase 2b Study of DIO-902 or DIO-902 Placebo in Addition to Metformin and Atorvastatin or Atorvastatin Placebo for Type 2 Diabetes

    Not yet reported DiObex 200 participants Est. completion 2008-12 24 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00494884

    Vildagliptin 100 mg Once Daily vs. Placebo as add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

    Not yet reported Novartis Est. completion 2008-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00499707

    Efficacy and Safety Study of Rosiglitazone/Metformin Therapy vs Rosiglitazone and Metformin in Type 2 Diabetes Subjects

    Not yet reported GlaxoSmithKline 453 participants Est. completion 2004-12-16 102 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00501020

    Comparison of the Efficacy and Tolerability of the Addition of AVANDIA to Submaximal Doses of Metformin

    Not yet reported GlaxoSmithKline 750 participants Est. completion 2003-02-13
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00501904

    Metformin in Infertile PCOS Patients

    Not yet reported University Magna Graecia 20 participants Est. completion 2016-12 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Withdrawn NCT NCT00502229

    Therapy for Infertile PCOS Patients Ovulating Under Clomiphene Citrate or Metformin

    Not yet reported University Magna Graecia 1 site
    Other conditions: Polycystic Ovary Syndrome, Infertility
    View official trial listing →
  • Completed NCT NCT00502710

    A Study of Dipeptidyl-peptidase IV (DPP-IV) RO4876904 in Patients With Type 2 Diabetes.

    Not yet reported Hoffmann-La Roche 289 participants Est. completion 2008-04 48 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00506194

    Short-Term Intensive Insulin Therapy Induction of Long-term Glycemic Control

    Not yet reported Taipei Veterans General Hospital, Taiwan 60 participants Est. completion 2011-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00506298

    Study of CRx-401 on Glucose Levels in Subjects With Type II Diabetes

    Not yet reported Zalicus 150 participants Est. completion 2009-05 18 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00510588

    Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease

    Not yet reported University of Leipzig 120 participants Est. completion 2013-10 1 site
    Cardiovascular diseasePrediabetes Other conditions: Obesity
    View official trial listing →
  • Terminated NCT NCT00510705

    Chronic Inflammatory Activation in Fat Tissue: An Atherogenic Factor in Severe Coronary Artery Disease

    Not yet reported University of Leipzig 29 participants 1 site
    Cardiovascular diseasePrediabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT00513630

    Study on the Prognosis and Effect of Anti-diabetic Drugs on Type-2 Diabetes Mellitus With Coronary Artery Disease

    Not yet reported Shanghai Jiao Tong University School of Medicine 304 participants Est. completion 2010-07 1 site
    Type 2 diabetesCardiovascular disease
    View official trial listing →
  • Completed NCT NCT00518882

    Effect of Liraglutide or Exenatide Added to an Ongoing Treatment on Blood Glucose Control in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 467 participants Est. completion 2009-04 125 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00519142

    Mitiglinide in Combination With Metformin vs. Metformin Alone in Patients With Type 2 Diabetes Mellitus

    Not yet reported Elixir Pharmaceuticals 367 participants Est. completion 2008-10 61 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00519480

    A Study To Assess The Safety And Tolerability Of GSK189075 When Given With A Total Daily Dose Of >/ 2000mg of Metformin

    Not yet reported GlaxoSmithKline 50 participants Est. completion 2008-04-01 4 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00525330

    A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of KRP-104 in Patients With Type 2 Diabetes Inadequately Controlled on Metformin Alone

    Not yet reported ActivX Biosciences, Inc. 213 participants Est. completion 2008-08 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00528372

    A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled With Diet and Exercise

    Not yet reported AstraZeneca 1067 participants Est. completion 2010-07 78 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00528879

    A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone

    Not yet reported AstraZeneca 915 participants Est. completion 2010-05 75 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00532935

    MK0431A vs. Pioglitazone in Patients With Type 2 Diabetes Mellitus (0431A-066)

    Not yet reported Merck Sharp & Dohme LLC 517 participants Est. completion 2009-10-23 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00536211

    Physical Inactivity and Insulin Resistance in Skeletal Muscle.

    Not yet reported University of Kansas Medical Center Est. completion 2011-12 1 site
    Metabolic syndrome Other conditions: Insulin Resistance, Hypertension, Hypercholesterolemia, Obesity
    View official trial listing →
  • Completed NCT NCT00538486

    A Randomized, Double-Blind, Active Control Trial Comparing Effects of Telmisartan, Candesartan and Amlodipine, Alone or Plus Metformin, on Non-Diabetic, Obese Hypertensive Patients

    Not yet reported Third Military Medical University 360 participants Est. completion 2009-06 1 site Stand-alone
    Other conditions: Hypertension, Obesity
    View official trial listing →
  • Completed NCT NCT00541437

    Type 2 Diabetes Patients Switched From Sulfonylurea With Metformin to Glyburide/Metformin Combination Tablet

    Genovate Biotechnology Co., Ltd., 12 participants Est. completion 2007-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00541567

    BMS-646256 in Obese and Overweight Type 2 Diabetics

    Not yet reported, Not yet reported Solvay Pharmaceuticals 600 participants Est. completion 2010-06
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00541775

    Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)

    Not yet reported Merck Sharp & Dohme LLC 273 participants Est. completion 2007-03 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00543361

    Study MK0767 and Metformin in Type 2 Diabetic Patients (0767-020)

    Not yet reported Merck Sharp & Dohme LLC 382 participants Est. completion 2003-12
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00543738

    MK0767 and Metformin Combination Study (0767-028)

    Not yet reported Merck Sharp & Dohme LLC 114 participants Est. completion 2003-12
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT00543751

    Placebo Controlled Metformin and Sulfonylurea Combination Study in Patients With Type 2 Diabetes (0767-025)

    Not yet reported Merck Sharp & Dohme LLC 610 participants Est. completion 2003-11
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00544518

    Impact of Benfluorex Versus Metformin on Glucose Control and Insulin Secretion in Chinese Type 2 Diabetic Patients

    Not yet reported Air Force Military Medical University, China 240 participants Est. completion 2008-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00545584

    Addition Of Januvia (Sitagliptin) Improves Glycemic Control In Patients Inadequately Controlled By Metformin (MK0431-078)

    Not yet reported Merck Sharp & Dohme LLC 1512 participants Est. completion 2009-11-19
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00546442

    Treatment Insulin Resistence in HCV G-1 Patient

    Not yet reported Valme University Hospital 126 participants Est. completion 2007-01 19 sites
    Other conditions: Chronic Hepatitis C
    View official trial listing →
  • Completed NCT NCT00546728

    The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes

    Not yet reported St. Paul Heart Clinic 50 participants Est. completion 2011-07 2 sites Added to GLP-1
    Prediabetes
    View official trial listing →
  • Completed NCT NCT00546741

    Drug Interaction With Metformin

    Not yet reported AstraZeneca 18 participants Est. completion 2008-02 1 site
    Other conditions: Healthy Male and Female Subjects
    View official trial listing →
  • Completed NCT NCT00558077

    Second-Line Treatments for Anovulatory Infertility in PCOS Patients

    Not yet reported University Magna Graecia 50 participants Est. completion 2005-10 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Infertility, Anovulation
    View official trial listing →
  • Completed NCT NCT00560690

    The Effect of Adding Metformin to the Treatment of Hepatitis C

    Not yet reported Tehran University of Medical Sciences 140 participants Est. completion 2010-12 1 site Stand-alone
    Other conditions: Hepatitis C
    View official trial listing →
  • Completed NCT NCT00562172

    Insulin Glargine (Lantus) vs Sulfonylurea (SU) for BETA Cell Function (BETA Study)

    Not yet reported Sanofi 75 participants Est. completion 2010-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00568984

    Efficacy and Safety of Repaglinide and Metformin Combined in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 324 participants Est. completion 2003-11-10 15 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00570739

    Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.

    Not yet reported Daiichi Sankyo 502 participants Est. completion 2009-05 31 sites Stand-alone
    Type 2 diabetesPrediabetes Other conditions: Hypercholesterolemia
    View official trial listing →
  • Terminated NCT NCT00571519

    Randomized, Double-blind, Active-controlled, Study of Rivoglitazone in Type 2 Diabetes Mellitus

    Not yet reported Daiichi Sankyo 94 participants Est. completion 2008-05-23 18 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00575588

    52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period

    Not yet reported AstraZeneca 891 participants Est. completion 2010-08 94 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00577590

    Effects of Fatty Acid Delivery on Heart Metabolism and Function in Type 2 Diabetes (T2DM

    Not yet reported Washington University School of Medicine 78 participants Est. completion 2012-09 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Completed NCT NCT00580710

    Investigation Into the Effects Upon Brain Response to Change in Circulating Glucose Levels in Diabetes Mellitus

    Yale University 164 participants Est. completion 2018-11-01 1 site
    Other conditions: Type 1 Diabetes, Hypoglycemia
    View official trial listing →
  • Withdrawn NCT NCT00588172

    Genetic Variation in OCT1 and Response to Metformin

    Not yet reported Mayo Clinic Est. completion 2011-06
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00592969

    Efficacy and Safety of Metformin Plus Biphasic Insulin Aspart 30 in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 164 participants Est. completion 2004-11-02 2 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00598793

    Biphasic Insulin Aspart 30 in Type 2 Diabetes Failing OAD Therapy

    Not yet reported Novo Nordisk A/S 242 participants Est. completion 2004-03 27 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00601250

    Efficacy and Safety of B I1356 (Linagliptin) vs. Placebo Added to Metformin Background Therapy in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 701 participants 82 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00602472

    BI 1356 (Linagliptin) in Combination With Metformin and a Sulphonylurea in Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 1058 participants 100 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00603239

    Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using a Thiazolidinedione or a Thiazolidinedione and Metformin

    Not yet reported AstraZeneca 165 participants Est. completion 2009-07 25 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00605475

    Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACZ885 in Patients With Type 2 Diabetes

    Not yet reported Novartis 231 participants Est. completion 2010-09 13 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00607867

    LoBAG30 Diet in Patients on Metformin

    Not yet reported US Department of Veterans Affairs 20 participants Est. completion 2011-03 1 site
    Other conditions: Diabetes Mellitus, Diet
    View official trial listing →
  • Completed NCT NCT00611884

    Comparison of Two NN1250 Formulations Versus Insulin Glargine, All in Combination With Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 245 participants Est. completion 2008-08 29 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00613951

    Comparison of Two NN5401 Formulations Versus Biphasic Insulin Aspart 30, All in Combination With Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 182 participants Est. completion 2008-08 31 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00614120

    Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 929 participants Est. completion 2009-02 50 sites Mixed
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00617240

    Strategies to Reduce Antipsychotic-Associated Weight Gain in Youth

    Not yet reported University of North Carolina, Chapel Hill 9 participants Est. completion 2012-10 1 site Stand-alone
    Other conditions: Weight Gain
    View official trial listing →
  • Completed NCT NCT00618007

    Effect of PF-00734200 in Subjects With Type 2 Diabetes

    Not yet reported Pfizer 289 participants Est. completion 2008-08 79 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00618072

    EMPOWIR:Enhance the Metabolic Profile of Women With Insulin Resistance

    Not yet reported New York Medical College 46 participants Est. completion 2011-01 1 site
    Other conditions: Hyperinsulinemia, Insulin Resistance, Obesity
    View official trial listing →
  • Completed NCT NCT00619697

    Efficacy and Safety of Biphasic Insulin Aspart 30 in Combination With Metformin in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 260 participants Est. completion 2005-03 54 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00620191

    Metformin in Amnestic Mild Cognitive Impairment

    Not yet reported Columbia University 80 participants Est. completion 2012-02 1 site Stand-alone
    Other conditions: Mild Cognitive Impairment
    View official trial listing →
  • Terminated NCT NCT00622089

    Open Label Safety & Pharmacodynamic Study 24Wk w/DIO-902 Combo w/Metformin & Atorvastatin in T2DM Patients

    Not yet reported, Not yet reported DiObex 150 participants Est. completion 2008-12 24 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00622284

    Efficacy and Safety of BI 1356 in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 1560 participants 221 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00622323

    Post Marketing Surveillance Study of Byetta ™ (Exenatide) Use Among Filipino Patients

    AstraZeneca 41 participants Est. completion 2009-09 3 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00624364

    Efficacy and Safety of Biphasic Insulin Aspart 30 With Metformin in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 140 participants Est. completion 2005-05 15 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00627445

    Effect of Biphasic Insulin Aspart 50 on Blood Glucose Control in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 441 participants Est. completion 2009-01 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00631007

    A Placebo Controlled Safety and Efficacy Study of INT131 Besylate in Type 2 Diabetes, With an Active Comparator

    Not yet reported InteKrin Therapeutics, Inc. 367 participants Est. completion 2009-09 66 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00631033

    DZX Mediated Insulin Suppression in Obese Men

    Not yet reported Rijnstate Hospital 51 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT00631488

    A Study to Test the Effectiveness and Safety of MK0893 in Combination With Other Drugs Used to Treat Type 2 Diabetes (0893-015)

    Not yet reported Merck Sharp & Dohme LLC 146 participants Est. completion 2009-01 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00633425

    Continuous Glucose Monitoring System (CGMS) in Type 2 Diabetic Patients Inadequately Controlled by Metformine Monotherapy; Analyze of Glycemic Profile Before and After Association of Glimepiride

    Not yet reported Sanofi 43 participants Est. completion 2003-10 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00636766

    Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque

    Not yet reported Aristotle University Of Thessaloniki 300 participants Est. completion 2009-01 1 site Stand-alone
    Cardiovascular diseaseType 2 diabetesMetabolic syndrome Other conditions: Carotid Atherosclerosis
    View official trial listing →
  • Completed NCT NCT00637273

    A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)

    Not yet reported AstraZeneca 514 participants Est. completion 2009-07 62 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00638716

    A Study to Evaluate the Efficacy and Safety of CJC-1134-PC in Patients With Type 2 Diabetes Mellitus Who Are Currently on Metformin Monotherapy

    Not yet reported ConjuChem 122 participants Est. completion 2008-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00641056

    Efficacy of Exenatide Once Weekly and Once-Daily Insulin Glargine in Patients With Type 2 Diabetes Treated With Metformin Alone or in Combination With Sulfonylurea (DURATION - 3)

    Not yet reported AstraZeneca 467 participants Est. completion 2009-11 75 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00641407

    Bedtime Insulins and Oral Antihyperglycemic Drugs in Type 2 Diabetes

    Not yet reported University of Campania Luigi Vanvitelli 100 participants Est. completion 2008-03 1 site
    Type 2 diabetes Other conditions: Hypoglycemia
    View official trial listing →
  • Completed NCT NCT00642278

    An Efficacy, Safety, and Tolerability Study of Canagliflozin (JNJ-28431754) in Patients With Type 2 Diabetes

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 451 participants Est. completion 2009-01 78 sites
    Other conditions: Diabetes Mellitus, Type II, Diabetes Mellitus, Non Insulin Dependent
    View official trial listing →
  • Completed NCT NCT00643851

    An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release Tablets

    Not yet reported AstraZeneca 994 participants Est. completion 2009-08 99 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00647023

    Incretin Secretion in Women With Polycystic Ovary Syndrome (PCOS)

    Not yet reported Hvidovre University Hospital 66 participants Est. completion 2006-05 Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00648492

    Food Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR 500 mg

    Not yet reported Mylan Pharmaceuticals Inc 18 participants Est. completion 2002-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00648505

    Food Study of Glipizide and Metformin HCl Tablets 5 mg/500 mg to Metaglip® Tablets 5 mg/500 mg

    Not yet reported Mylan Pharmaceuticals Inc 36 participants Est. completion 2005-06 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00648518

    Fasting Study of Metformin Hydrochloride ER Tablets 750 mg and Glucophage® XR Tablets 750 mg

    Not yet reported Mylan Pharmaceuticals Inc 36 participants Est. completion 2003-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Withdrawn NCT NCT00648869

    Open-label Crossover Metformin Gum Versus Tablet in Healthy Volunteers

    Not yet reported Hadassah Medical Organization 12 participants Est. completion 2008-11 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00649350

    Food Study Metformin Hydrochloride ER Tablets 750 mg and Glucophage XR 750 mg

    Not yet reported Mylan Pharmaceuticals Inc 28 participants Est. completion 2003-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00649454

    Fasting Study of Glipizide and Metformin HCl Tablets 5 mg/500 mg to Metaglip® Tablets 5 mg/500 mg

    Not yet reported Mylan Pharmaceuticals Inc 36 participants Est. completion 2005-06 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00649948

    Food BE Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage XR 500 mg

    Not yet reported Mylan Pharmaceuticals Inc 27 participants Est. completion 2004-06 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00650234

    Fasting BE Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

    Not yet reported Mylan Pharmaceuticals Inc 47 participants Est. completion 2004-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00650312

    Fasting Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg

    Not yet reported Mylan Pharmaceuticals Inc 50 participants Est. completion 2002-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00653185

    Efficacy of SYR-472 in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Takeda 369 participants Est. completion 2008-03 87 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00653302

    Phenotype Evaluation in Insulin Naive Patients Using Lantus (Insulin Glargine)

    Not yet reported Sanofi 280 participants Est. completion 2005-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00657943

    The Copenhagen Insulin and Metformin Therapy Trial

    Not yet reported Steno Diabetes Center Copenhagen 415 participants Est. completion 2012-12 9 sites Stand-alone
    Type 2 diabetes Other conditions: Atherosclerosis, Arteriosclerosis
    View official trial listing →
  • Completed NCT NCT00660907

    Efficacy and Safety of Dapagliflozin in Combination With Metformin in Type 2 Diabetes Patients

    Not yet reported AstraZeneca 1217 participants Est. completion 2013-01 76 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00661362

    Evaluate Efficacy and Safety of Saxagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes

    Not yet reported AstraZeneca 570 participants Est. completion 2009-09 30 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00661921

    A Randomized Double Blind, Placebo Controlled Trial With AMG 108 in Patients With Type 2 Diabetes Mellitus

    Not yet reported Amgen Est. completion 2009-10
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00664846

    Standard Medical Management in Secondary Prevention of Ischemic Stroke in China

    Not yet reported Peking Union Medical College Hospital 4000 participants Est. completion 2011-04 46 sites Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00666458

    18-week add-on to Metformin Comparison of Saxagliptin and Sitagliptin in Adult Patients With Type 2 Diabetes (T2D)

    Not yet reported AstraZeneca 822 participants Est. completion 2009-03 87 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00667498

    Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance

    Not yet reported Yale University 28 participants Est. completion 2007-12 1 site Stand-alone
    Other conditions: Pediatric Obesity, Insulin Resistance, Hyperinsulinemia
    View official trial listing →
  • Completed NCT NCT00667732

    How Glargine Insulin, Oral Diabetes Medications and Exenatide May Improve Blood Sugar Control and Weight Gain in Type 2 Diabetics

    Not yet reported Oregon Health and Science University 41 participants Est. completion 2010-04 3 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00669864

    Effect of Biphasic Insulin Aspart 30 Combined With Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin

    Not yet reported Novo Nordisk A/S 293 participants Est. completion 2009-04 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00670800

    Study of Brain Function in Women With Insulin Resistant Polycystic Ovary Syndrome

    Not yet reported University of Michigan 14 participants Est. completion 2009-08 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00672386

    A Study of the Safety and Effectiveness of a R256918 in Patients With Type 2 Diabetes

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 352 participants Est. completion 2008-09 62 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes Mellitus, Endocrine System Diseases, Nutritional and Metabolic Diseases
    View official trial listing →
  • Withdrawn NCT NCT00672464

    Cardio Risk of Acute Schizophrenia Olanzapine Duke

    Not yet reported Duke University Est. completion 2010-02 2 sites Stand-alone
    Other conditions: Schizophrenia, Schizoaffective Disorder
    View official trial listing →
  • Completed NCT NCT00673465

    Effect of SCH 497079 on Metabolic Parameters and Influence of Race/Ethnic Origin on Therapeutic Response (Study P05338)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 17 participants Est. completion 2008-12-11 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00674466

    A Study to Evaluate the Efficacy and Safety of CJC-1134-PC in Patients With Type 2 Diabetes Who Are Currently on Metformin Monotherapy

    Not yet reported ConjuChem 90 participants Est. completion 2008-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00676338

    Safety and Efficacy of Exenatide Once Weekly Injection Versus Metformin, Dipeptidyl Peptidase-4 Inhibitor, or Thiazolidinedione as Monotherapy in Drug-Naive Patients With Type 2 Diabetes (DURATION-4)

    Not yet reported AstraZeneca 820 participants Est. completion 2011-01 106 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00678080

    Metformin Versus Insulin in Pregnant Women With Type 2 Diabetes

    Not yet reported The University of Texas Health Science Center, Houston 25 participants Est. completion 2011-08 3 sites Stand-alone
    Other conditions: Pregnancy Complications
    View official trial listing →
  • Completed NCT NCT00679237

    Risk Reduction in Coronary Heart Disease

    Not yet reported Sorlandet Hospital HF 1600 participants Est. completion 2019-12 1 site
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Completed NCT NCT00679939

    Study In Postmenopausal Women With Type 2 Diabetes Looking At Approved Diabetes Drugs And How They Affect Bone Health

    Not yet reported GlaxoSmithKline 226 participants Est. completion 2010-09-16 42 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00680745

    Efficacy and Safety of Dapagliflozin in Combination With Glimepiride (a Sulphonylurea) in Type 2 Diabetes Patients

    Not yet reported AstraZeneca 597 participants Est. completion 2010-05 66 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00681460

    Metformin in Gestational Diabetes Mellitus

    Not yet reported K. Marcinkowski University of Medical Sciences 78 participants Est. completion 2013-05 1 site Stand-alone
    Other conditions: Diabetes, Gestational, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT00682448

    Metformin for the Prevention of the Metabolic Side-effects of Zyprexa

    Not yet reported Rush University Medical Center 25 participants Est. completion 2011-08 1 site
    Other conditions: Metabolic Complications
    View official trial listing →
  • Terminated NCT NCT00682890

    Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS)

    Not yet reported Virginia Commonwealth University 28 participants Est. completion 2010-01 1 site
    Other conditions: Polycystic Ovary Syndrome, PCOS, Insulin Sensitivity
    View official trial listing →
  • Completed NCT NCT00683657

    Safety and Efficacy Study of Subjects That Are Taking Saxagliptin Added Onto Metformin XR Compared to Subjects Taking Metformin XR Alone

    Not yet reported AstraZeneca 93 participants Est. completion 2009-02 27 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00683735

    Quantification of the Dipeptidyl Peptidase (DPP)-4 Inhibition-mediated Enhancement of the Activity of the Entero-insular Axis

    Not yet reported, Not yet reported Michael A. Nauck 20 participants Est. completion 2013-12 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT00684528

    A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin

    Not yet reported Meir Medical Center 1000 participants Est. completion 2012-12 1 site Stand-alone
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT00686634

    Sitagliptin in Combination With Metformin and Sulfonylurea

    Not yet reported Charles Drew University of Medicine and Science 108 participants Est. completion 2010-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00690456

    Effect of Rimonabant and Metformin Combination on Glycemic Control in Patients With Type 2 Diabetes

    Not yet reported Sanofi 403 participants Est. completion 2009-02 13 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00690755

    Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome

    VA Office of Research and Development 157 participants Est. completion 2012-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00691314

    Efficacy and Safety of Stent Implantation in Symptomatic Extra- and Intracranial Artery Stenosis

    Not yet reported Peking Union Medical College Hospital 300 participants Est. completion 2010-12 10 sites Stand-alone
    Cardiovascular disease Other conditions: Transient Ischemic Attack, Atherosclerosis, Stenosis, Stents
    View official trial listing →
  • Completed NCT NCT00694057

    Safety, Tolerance and Activity of HE3286 in Patients With Type 2 Diabetes Mellitus

    Not yet reported Harbor Therapeutics 164 participants Est. completion 2010-01 22 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00694759

    Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)

    Not yet reported Oregon Health and Science University 37 participants Est. completion 2011-07 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00696657

    A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and Liraglutide

    Not yet reported Novo Nordisk A/S 415 participants Est. completion 2009-02-05 77 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT00696982

    The Effect of Sitagliptin on Hypertension, Arterial Stiffness, Oxidative Stress and Inflammation

    Not yet reported Assaf-Harofeh Medical Center 60 participants Est. completion 2009-06 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Arterial Stiffness
    View official trial listing →
  • Completed NCT NCT00698230

    Safety and Efficacy of INCB013739 Plus Metformin Compared to Metformin Alone on Glycemic Control in Type 2 Diabetics

    Not yet reported Incyte Corporation 302 participants Est. completion 2009-05 68 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00698789

    Evaluate the Safety and Tolerability of INCB019602 When Administered With Metformin in Patients With Type 2 Diabetes

    Not yet reported Incyte Corporation 48 participants Est. completion 2009-06 22 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00699036

    Rosiglitazone Versus Rosiglitazone and Metformin Versus Rosiglitazone and Avandia in the Treatment of Nonalcoholic Steatohepatitis (NASH)

    Not yet reported Brooke Army Medical Center 165 participants Est. completion 2009-08 1 site Stand-alone
    MASHMASLD
    View official trial listing →
  • Status unknown NCT NCT00699322

    Effect of Dipeptidyl Peptidase-IV Inhibitor and Sulfonylurea on Glucose Variability and Oxidative Stress

    Not yet reported The Catholic University of Korea 36 participants Est. completion 2010-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00700817

    The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Novo Nordisk A/S 665 participants Est. completion 2010-06 166 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT00700856

    Thiazolidinediones Or Sulphonylureas and Cardiovascular Accidents.Intervention Trial

    Not yet reported Italian Society of Diabetology 3371 participants Est. completion 2018-12 61 sites Stand-alone
    Type 2 diabetesCardiovascular disease
    View official trial listing →
  • Completed NCT NCT00701090

    A Study to Test the Safety and Efficacy of Sitagliptin Compared to Glimepiride in Patients With Type 2 Diabetes on a Stable Dose of Metformin (0431-803)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 1035 participants Est. completion 2009-10 Stand-alone
    Type 2 diabetes Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Terminated NCT NCT00701935

    Effect of Exenatide on Abdominal Fat Distribution in Patients With Type 2 Diabetes Pretreated With Metformin

    Not yet reported AstraZeneca 80 participants Est. completion 2012-01 17 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00703508

    Pharmacogenetics of Metformin Action in PCOS

    Not yet reported Virginia Commonwealth University 55 participants Est. completion 2014-03 2 sites Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00703755

    A Randomized, Double-Blind Trial Comparing the Efficacy and Safety of Fenofibrate, Metformin, Their Combination and Placebo in Patients With Metabolic Syndrome.

    Not yet reported Solvay Pharmaceuticals 2288 participants Est. completion 2004-06 101 sites Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT00707031

    GLP-1 Receptor Agonist Lixisenatide Versus Exenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin

    Not yet reported Sanofi 639 participants Est. completion 2010-11 18 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00708578

    Optimal Oral Hypoglycaemic Agents (OHA) for Combination With Insulin Glargine (Sulfonylurea vs. Metformin)

    Not yet reported Sanofi 99 participants Est. completion 2009-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00709917

    Observational Study of the Switch of Metformin Alone to Metformin Combined With Repaglinide in Type 2 Diabetes

    Novo Nordisk A/S 2171 participants Est. completion 2008-01 2 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00712673

    GLP-1 Receptor Agonist Lixisenatide (Morning or Evening) in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin

    Not yet reported Sanofi 680 participants Est. completion 2011-03 16 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00713830

    GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Sulfonylurea

    Not yet reported Sanofi 859 participants Est. completion 2011-01 16 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00714233

    Treatment of Adolescent Polycystic Ovary Syndrome (PCOS)

    Not yet reported University of Rochester 43 participants Est. completion 2007-12 Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00715624

    GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Basal Insulin

    Not yet reported Sanofi 496 participants Est. completion 2011-02 15 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00717457

    A Study of Taspoglutide Versus Exenatide for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin, Thiazolidinedione or a Combination of Both.

    Not yet reported Hoffmann-La Roche 1189 participants Est. completion 2011-03 216 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00720161

    Metformin in Children With Motor Deficit

    Not yet reported Universitaire Ziekenhuizen KU Leuven 42 participants Est. completion 2011-07 1 site
    Other conditions: Spina Bifida, Neuromuscular Diseases
    View official trial listing →
  • Completed NCT NCT00722371

    MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2)

    Not yet reported Merck Sharp & Dohme LLC 1615 participants Est. completion 2011-03-25 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00723307

    Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study

    Not yet reported Professor Naveed Sattar 173 participants Est. completion 2012-12 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00727857

    Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.

    Not yet reported Takeda 600 participants Est. completion 2008-08 77 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00729326

    Comparison of the Effect of Exenatide Versus Sitagliptin on 24-hour Average Glucose in Patients With Type 2 Diabetes on Metformin or a Thiazolidinedione

    Not yet reported AstraZeneca 83 participants Est. completion 2009-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00736385

    Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)

    Not yet reported Duke University 11 participants Est. completion 2012-12 1 site
    Other conditions: Fatty Liver
    View official trial listing →
  • Completed NCT NCT00740051

    A Randomised, db, Placebo-controlled Study of BI 1356 for 18 Weeks Followed by a 34 Week Double-blind Extension Period (Placebo Patients Switched to Glimepiride) in Type 2 Diabetic Patients for Whom Treatment With Metformin is Inappropriate

    Not yet reported Boehringer Ingelheim 227 participants 53 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00743002

    A Trial of TT223 in Patients With Type 2 Diabetes Who Are Taking Metformin and/or Thiazolidinedione

    Not yet reported OPKO Health, Inc. 87 participants Est. completion 2009-12 20 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00744367

    A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Plus Pioglitazone.

    Not yet reported Hoffmann-La Roche 326 participants Est. completion 2010-11 113 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00745433

    Switch From Metformin Monotherapy to a Bitherapy With Metformin and Repaglinide

    Novo Nordisk A/S 906 participants Est. completion 2009-03 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00749190

    BI 10773 add-on to Metformin in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 495 participants 116 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00751114

    Evaluation of Insulin Glargine Versus Sitagliptin in Insulin-naive Patients

    Not yet reported Sanofi 515 participants Est. completion 2011-07 17 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00753896

    Safety of Exenatide Once Weekly in Patients With Type 2 Diabetes Mellitus Treated With Thiazolidinedione Alone or Thiazolidinedione in Combination With Metformin

    Not yet reported AstraZeneca 134 participants Est. completion 2009-11 26 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00754403

    Efficacy of Pioglitazone and Fortamet Combination Therapy in Subjects With Type 2 Diabetes

    Not yet reported Takeda 312 participants Est. completion 2006-10 Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Withdrawn NCT NCT00754689

    Study of Rimonabant/Metformin Combinations to Investigate Diabetes (Blood Sugar) Control in Patients With Type 2 Diabetes

    Not yet reported Sanofi Est. completion 2008-11 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00754988

    A Study of Taspoglutide Versus Sitagliptin for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin.

    Not yet reported Hoffmann-La Roche 666 participants Est. completion 2011-03 148 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00755287

    A Study of the Safety, Tolerability and Effect on Glycemic Control of Taspoglutide Versus Insulin Glargine in Insulin Naive Type 2 Diabetic Patients Inadequately Controlled With Metformin Plus Sulphonylurea.

    Not yet reported Hoffmann-La Roche 1072 participants Est. completion 2010-12 210 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00755846

    Safety and Efficacy Study of Alogliptin on Glycemic Control in Subjects With Type 2 Diabetes.

    Not yet reported Takeda 265 participants Est. completion 2005-10
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00757588

    Safety and Efficacy of Saxagliptin Plus Insulin With or Without Metformin

    Not yet reported AstraZeneca 455 participants Est. completion 2010-04 80 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00760344

    Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Takeda 386 participants Est. completion 2008-03 112 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT00762957

    Safety and Efficacy of TAK-559 in Combination With Metformin in Patients With Type 2 Diabetes Mellitus.

    Not yet reported Takeda 15 participants Est. completion 2004-12 Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00763451

    GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin

    Not yet reported Sanofi 484 participants Est. completion 2011-01 15 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00763815

    GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Pioglitazone

    Not yet reported Sanofi 484 participants Est. completion 2011-06 150 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00765817

    Addition Of Exenatide To Insulin Glargine In Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 261 participants Est. completion 2010-01 59 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00767000

    Dose Range Finding Study of MK-0941 in Patients With Type 2 Diabetes Mellitus on Insulin (MK-0941-007 AM3 EXT1 AM1)(TERMINATED)

    Not yet reported Merck Sharp & Dohme LLC 813 participants Est. completion 2010-06 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00767351

    Variation in Serum Levels of Metformin in Patients With Reduced Renal Function

    Skane University Hospital 30 participants Est. completion 2009-07
    Type 2 diabetes Other conditions: Metformin, Pharmacokinetics
    View official trial listing →
  • Completed NCT NCT00770445

    Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus.

    Not yet reported Takeda 121 participants Est. completion 2010-07 18 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00770653

    Efficacy of Pioglitazone/Metformin Combination Therapy in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia.

    Not yet reported Takeda 305 participants Est. completion 2009-05 64 sites Stand-alone
    Other conditions: Diabetes Mellitus, Dyslipidemias
    View official trial listing →
  • Completed NCT NCT00770835

    Efficacy and Safety of Pioglitazone in Treating Subjects With Vascular Complications Associated With Type 2 Diabetes Mellitus.

    Not yet reported Takeda 39 participants Est. completion 2011-05 2 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00772174

    Efficacy and Safety Study of Pioglitazone Combined With Metformin on Metabolic Syndrome in Subjects With Type 2 Diabetes

    Not yet reported Takeda 418 participants Est. completion 2008-02 Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00774553

    To Evaluate Safety and Tolerability After Multiple Oral Doses of AZD1656 in Type 2 Diabetes Patients on Top of Metformin

    Not yet reported AstraZeneca 70 participants Est. completion 2010-01 2 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00775164

    Pioglitazone Therapy in Obese Children With Insulin Resistance: A Randomized, Controlled Pilot Study

    Not yet reported University of Minnesota Est. completion 2011-02
    Other conditions: Obesity, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT00776607

    Randomized Controlled Trial of Insulin Versus Tablets for Latent Autoimmune Diabetes in Adults (LADA)

    Not yet reported Abertawe Bro Morgannwg University NHS Trust 200 participants Est. completion 2011-04 2 sites
    Other conditions: Latent Autoimmune Diabetes in Adults LADA
    View official trial listing →
  • Completed NCT NCT00778141

    Bioequivalence Study of Metformin HCl 750 mg XR Tablets Under Non Fasting Conditions

    Not yet reported Ranbaxy Laboratories Limited 36 participants Est. completion 2004-06 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00778349

    A Comparitive Bioavailability Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fasting Conditions and After Low and High Fat Meal

    Not yet reported Ranbaxy Laboratories Limited 34 participants Est. completion 2002-07 Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00778427

    Bioequivalence Study of Metformin Hydrochloride 1000mg Tablets Under Fasting Conditions

    Not yet reported Ranbaxy Laboratories Limited 32 participants Est. completion 2006-04 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00778466

    Bioequivalence Study of Metformin Hydrochloride 1000mg Tablets Under Fed Conditions

    Not yet reported Ranbaxy Laboratories Limited 32 participants Est. completion 2006-04 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00778791

    Bioequivalence Study of Metformin HCl 750 mg XR Under Fasting Conditions

    Not yet reported Ranbaxy Laboratories Limited 60 participants Est. completion 2004-07 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00780013

    Bioequivalence Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fed Conditions

    Not yet reported Ranbaxy Laboratories Limited 36 participants Est. completion 2002-06 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00780715

    Response To Oral Agents in Diabetes (ROAD)- Pilot Study

    Not yet reported University of Dundee 29 participants Est. completion 2009-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00783744

    Insulin Glargine Combination Therapies in Type II Diabetics

    Not yet reported Sanofi 375 participants 10 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00789035

    12 Weeks Treatment With 3 Different Doses of BI 10773 in Type 2 Diabetic Patients

    Not yet reported Boehringer Ingelheim 408 participants 74 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00789191

    Effect of Detemir and Sitagliptin on Blood Glucose Control in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 222 participants Est. completion 2009-08 51 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT00790348

    Effect of Januvia on Ghrelin and Other Gut Hormones in Patients With Diabetes

    Wayne State University 45 participants 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00792935

    A Study to Test MK-0941 in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-0941-017)

    Not yet reported Merck Sharp & Dohme LLC 143 participants Est. completion 2010-02 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00794963

    Aggressive Treatment of Metabolic Syndrome in Patients Receiving Clozapine for Schizophrenia

    Not yet reported Northwell Health 8 participants Est. completion 2010-05 1 site Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT00795808

    PCOSMIC Trial - PolyCystic Ovary Syndrome, Metformin for Infertility With Clomiphene

    Not yet reported University of Auckland, New Zealand 171 participants Est. completion 2008-10 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00798161

    Safety and Efficacy of Linagliptin (BI 1356) Plus Metformin in Type 2 Diabetes, Factorial Design

    Not yet reported Boehringer Ingelheim 857 participants 138 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00802100

    Comparison of Optimal Antipsychotic Treatments for Adults With Schizophrenia

    Not yet reported National Institute of Mental Health (NIMH) 21 participants Est. completion 2009-10 13 sites Stand-alone
    Other conditions: Schizophrenia
    View official trial listing →
  • Completed NCT NCT00806234

    Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics

    Not yet reported Johns Hopkins University 127 participants Est. completion 2014-03 4 sites Stand-alone
    Other conditions: Psychotic Disorders
    View official trial listing →
  • Completed NCT NCT00806520

    Use of Continuous Glucose Monitoring Combined With Ambulatory Glucose Profiles to Characterize Glycemic Control

    HealthPartners Institute 16 participants Est. completion 2011-08 5 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00807092

    Comparing the Efficacy and Safety of Biphasic Insulin Aspart 30 and Biphasic Human Insulin 30 on Blood Sugar Control in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 145 participants Est. completion 2009-10 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT00809536

    Investigation Of How PD 0332334 And Metformin Are Eliminated From The Body When They Are Administered At The Same Time

    Not yet reported Pfizer 24 participants Est. completion 2009-02 1 site
    Other conditions: Generalized Anxiety Disorder
    View official trial listing →
  • Completed NCT NCT00813995

    A Study to Test the Safety and Efficacy of Adding Sitagliptin in Patients With Type 2 Diabetes Mellitus (MK0431-074)

    Not yet reported Merck Sharp & Dohme LLC 395 participants Est. completion 2010-08-09 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00814294

    Study of Two Doses of Oral HDV-Insulin and Placebo With Background Metformin Treatment in Patients With Type 2 Diabetes Mellitus

    Not yet reported, Not yet reported Diasome Pharmaceuticals 239 participants Est. completion 2009-09 40 sites
    Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT00814372

    Evaluate Safety and Effectiveness of MBX-102 in Type 2 Diabetes Patients With Poor Glycemic Control on Metformin

    Not yet reported Gilead Sciences 242 participants Est. completion 2010-02 26 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00815399

    Pioglitazone Versus Metformin in Type 2 Diabetes

    Not yet reported University of Campania Luigi Vanvitelli 150 participants Est. completion 2015-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00816907

    The Use of Metformin in the Treatment of Antipsychotic-Induced Weight Gain in Schizophrenia (The METS Study)

    Not yet reported National Institute of Mental Health (NIMH) 146 participants Est. completion 2010-03 16 sites Stand-alone
    Other conditions: Schizophrenia
    View official trial listing →
  • Completed NCT NCT00817271

    To Evaluate the Response to Glucagon During Hypoglycemia

    Not yet reported AstraZeneca 8 participants Est. completion 2009-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00817778

    Study to Assess the Safety and Tolerability After Multiple Oral Doses of AZD1656 in Patients With Type 2 Diabetes Mellitus Treated With Metformin

    Not yet reported AstraZeneca 27 participants Est. completion 2009-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00818077

    Using Continuous Glucose Monitoring to Understand the Glycemic Impact of Food

    HealthPartners Institute 15 participants Est. completion 2010-09 1 site
    Type 2 diabetes Other conditions: Currently Taking Metformin
    View official trial listing →
  • Completed NCT NCT00819325

    Prevention of Instent Renarrowing With Aggressive Glucose Lowering With Pioglitazone in Diabetic Patients

    Not yet reported Queen Elizabeth II Health Sciences Centre 50 participants Est. completion 2007-03 1 site Stand-alone
    Cardiovascular diseaseType 2 diabetes Other conditions: Angina Pectoris, Percutaneous Coronary Intervention
    View official trial listing →
  • Completed NCT NCT00819741

    Comparison of the Blood Sugar Lowering Effect Between Repaglinide Plus Metformin and Repaglinide Alone in Type 2 Diabetics Not Previously Treated With Oral Sugar-lowering Drugs

    Not yet reported Novo Nordisk A/S 433 participants Est. completion 2009-11 17 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00819884

    To Evaluate 24-hr Glucose After OD vs BD AZD1656

    Not yet reported AstraZeneca 36 participants Est. completion 2009-05 1 site
    Other conditions: Type II Diabetes
    View official trial listing →
  • Completed NCT NCT00820573

    Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DM

    Not yet reported The University of Texas Health Science Center at San Antonio 16 participants Est. completion 2012-10 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00822211

    Efficacy of add-on Therapy With Vildagliptin in Chinese Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy

    Not yet reported Novartis 404 participants Est. completion 2009-12 17 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00823680

    A Study of RO5093151 and RO5027838 in Patients With Type 2 Diabetes Mellitus on a Stable Dose of Metformin

    Not yet reported Hoffmann-La Roche 110 participants Est. completion 2009-08 5 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00823992

    A Study of Taspoglutide Versus Placebo for the Treatment of Obese Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Monotherapy

    Not yet reported Hoffmann-La Roche 305 participants Est. completion 2010-05 71 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00830076

    A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)

    Not yet reported Merck Sharp & Dohme LLC 18 participants Est. completion 2009-05-14 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00832390

    Study to Assess the Efficacy and Safety of Sitagliptin in Recently Diagnosed, Naive Type 2 Diabetics With Inadequate Glycemic Control on Diet and Exercise (0431-158)

    Not yet reported Merck Sharp & Dohme LLC 29 participants Est. completion 2008-07-11 Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT00832481

    Comparison of the Effects of Repaglinide and Metformin on Glucose Excursions

    Not yet reported Chinese PLA General Hospital 60 participants Est. completion 2009-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00833027

    ALPHA Sitagliptin Add on to Metformin (0431-103)

    Not yet reported Merck Sharp & Dohme LLC 608 participants Est. completion 2009-10-30
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00834587

    5 mg Glipizide/500 mg Metformin Hydrochloride Tablets, Non-Fasting

    Not yet reported Teva Pharmaceuticals USA 40 participants Est. completion 2004-06 2 sites Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00834613

    Metformin ER 750 mg Tablets, Fed

    Not yet reported Teva Pharmaceuticals USA 32 participants Est. completion 2003-08 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00834652

    Adding an Insulin-Sensitizing Medication to Depression Treatment for People Who Are Depressed and Overweight

    Not yet reported Washington University School of Medicine 206 participants Est. completion 2013-05 1 site Stand-alone
    Other conditions: Depression
    View official trial listing →
  • Completed NCT NCT00834743

    Metformin ER 750 mg Tablets, Fasting

    Not yet reported Teva Pharmaceuticals USA 32 participants Est. completion 2003-08 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00835497

    5 mg Glipizide/500 mg Metformin Hydrochloride Tablets, Fasting

    Not yet reported Teva Pharmaceuticals USA 40 participants Est. completion 2004-06 2 sites Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00835861

    Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes

    Not yet reported University of North Carolina, Chapel Hill 31 participants Est. completion 2010-04 1 site Stand-alone
    Other conditions: Non Insulin Dependent Diabetes, Pregnancy
    View official trial listing →
  • Completed NCT NCT00835991

    Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fed

    Not yet reported Teva Pharmaceuticals USA 60 participants Est. completion 2003-02 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00836472

    Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fasting

    Not yet reported Teva Pharmaceuticals USA 60 participants Est. completion 2003-04 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00838903

    Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes

    Not yet reported GlaxoSmithKline 1049 participants Est. completion 2013-04 386 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00839527

    A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes

    Not yet reported GlaxoSmithKline 685 participants Est. completion 2013-04 358 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00842140

    Safety of Hormonal Contraceptives Therapies in Polycystic Ovary Syndrome (PCOS) Women

    Not yet reported University of Sao Paulo 75 participants Est. completion 2009-01 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00842400

    A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.

    Not yet reported VIVUS LLC 20 participants Est. completion 2009-04 1 site
    Other conditions: Obesity
    View official trial listing →
  • Status unknown NCT NCT00845936

    Metformin for Weight Control in Adolescents Taking Atypical Antipsychotics

    Not yet reported BeerYaakov Mental Health Center 30 participants Est. completion 2010-05 1 site Stand-alone
    Other conditions: Drug Induced Weight Gain
    View official trial listing →
  • Completed NCT NCT00849056

    Safety and Efficacy of Albiglutide in Type 2 Diabetes

    Not yet reported GlaxoSmithKline 310 participants Est. completion 2013-01 331 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00851903

    Evaluation of Insulin Glargine in Combination With Sitagliptin in Type 2 Diabetes Patients: EASIE Extension Trial

    Not yet reported Sanofi 112 participants Est. completion 2011-09 16 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00855166

    Evaluation of the Effect of Dapagliflozin in Combination With Metformin on Body Weight in Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 182 participants Est. completion 2011-12 21 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00856284

    Efficacy and Safety of Alogliptin Plus Metformin Compared to Glipizide Plus Metformin in Patients With Type 2 Diabetes Mellitus

    Not yet reported Takeda 2639 participants Est. completion 2012-10 261 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00856986

    The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 987 participants Est. completion 2010-11 233 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00857870

    Insulin Glargine First Line vs Metformin in Type 2 Diabetic Subjects

    Not yet reported GWT-TUD GmbH 96 participants Est. completion 2011-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00859898

    Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 Diabetes

    Not yet reported AstraZeneca 1093 participants Est. completion 2010-05 123 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00860288

    Efficacy and Long-Term Safety of Vildagliptin as Add-on Therapy to Metformin in Patients With Type 2 Diabetes

    Not yet reported, Not yet reported Novartis Pharmaceuticals 1988 participants Est. completion 2011-03 187 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00864669

    A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Non-fasting Conditions

    Not yet reported Actavis Inc. 32 participants Est. completion 2002-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00864734

    A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Non-fasting Conditions

    Not yet reported Actavis Inc. 24 participants Est. completion 2002-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865033

    A Relative Bioavailability Study of Metformin HCL Tablets, 1000 mg Under Fasting Conditions

    Not yet reported Sandoz 32 participants Est. completion 2005-11 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00865072

    A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 40 participants Est. completion 2003-08 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865241

    A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 36 participants Est. completion 2002-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865436

    A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 36 participants Est. completion 2004-04 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865748

    A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 40 participants Est. completion 2004-01 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865839

    A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 32 participants Est. completion 2002-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865852

    A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Non-fasting Conditions

    Not yet reported Actavis Inc. 40 participants Est. completion 2003-08 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT00868790

    A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)

    Not yet reported Merck Sharp & Dohme LLC 118 participants Est. completion 2010-07-13 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00870194

    A Comparison of Adding Exenatide With Switching to Exenatide in Patients With Type 2 Diabetes Experiencing Inadequate Glycemic Control With Sitagliptin Plus Metformin

    Not yet reported AstraZeneca 255 participants Est. completion 2010-04 36 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00871936

    A Comparison of SLx-4090 in Combination With Metformin Versus Metformin Therapy Alone in Patients With Type 2 Diabetes

    Not yet reported Response Pharmaceuticals 82 participants Est. completion 2009-10 12 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00875394

    Study to Assess the Efficacy and Safety of Sitagliptin Added to the Regimen of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (0431-189)

    Not yet reported Merck Sharp & Dohme LLC 68 participants Est. completion 2008-06-27 Stand-alone
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00881530

    Empagliflozin (BI 10773) in Type Two Diabetes (T2D) Patients, Open Label Extension

    Not yet reported Boehringer Ingelheim 660 participants 137 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00881725

    A Study of Pre-operative Metformin in Prostate Cancer

    Not yet reported University Health Network, Toronto 24 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT00883259

    Metformin and Gestational Diabetes in High-risk Patients: a RCTs

    Not yet reported University Magna Graecia 80 participants 3 sites Stand-alone
    Other conditions: Obesity, Polycystic Ovary Syndrome, Gestational Diabetes
    View official trial listing →
  • Terminated NCT NCT00883766

    Polycystic Ovary Syndrome (PCOS) and In Vitro Fertilization (IVF): A Comparison Between Standard Long Protocol Versus an Antagonist Protocol Starting on Day 1

    Not yet reported Fundacion Dexeus 172 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, In Vitro Fertilization
    View official trial listing →
  • Completed NCT NCT00885378

    Efficacy and Safety Study of Saxagliptin + Metformin Immediate Release (IR) Versus Metformin IR Alone in Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 166 participants Est. completion 2010-02 41 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00889876

    Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents

    Not yet reported Maria Sandberg Westerstahl 26 participants Est. completion 2015-12 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT00892073

    Hypothalamic Obesity Following Craniopharyngioma Surgery: A Pilot Trial of Combined Metformin and Diazoxide Therapy

    Not yet reported The Hospital for Sick Children 9 participants Est. completion 2008-01 1 site Stand-alone
    Other conditions: Hypothalamic Obesity
    View official trial listing →
  • Completed NCT NCT00894322

    A Study to Examine the Pharmacokinetics, Tolerability, Safety and Efficacy of Exenatide Once Weekly Suspension

    Not yet reported, Not yet reported AstraZeneca 65 participants Est. completion 2009-08 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00897390

    Bioequivalence Study of Saxagliptin and Glucophage Combination Formulations in Healthy Subjects (B)

    Not yet reported AstraZeneca 24 participants Est. completion 2009-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00897884

    Clinical and Biologic Effects of Metformin in Early Stage Breast Cancer

    Not yet reported Mount Sinai Hospital, Canada 39 participants Est. completion 2011-07 2 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00899470

    Bioequivalence Study of Saxagliptin and Glucophage Combination Formulations in Healthy Subjects (A)

    Not yet reported AstraZeneca 24 participants Est. completion 2009-08 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00900146

    Dose Finding, Safety and Efficacy of Monthly Subcutaneous Canakinumab Administration in Metformin Monotherapy Treated Type 2 Diabetic Patients

    Not yet reported, Not yet reported Novartis 556 participants Est. completion 2010-11 106 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00901979

    A 12 Week Study in Patients With Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Novartis Pharmaceuticals 693 participants Est. completion 2010-06 67 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00909480

    Effect of Insulin Detemir and Insulin Glargine on Blood Glucose Control in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 457 participants Est. completion 2010-06 88 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00909506

    Efficacy and Safety of Adjuvant Metformin for Operable Breast Cancer Patients

    Not yet reported Seoul National University Hospital 105 participants Est. completion 2011-12 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00909597

    A Study of Taspoglutide Versus Pioglitazone in Patients With Type 2 Diabetes

    Not yet reported Hoffmann-La Roche 756 participants Est. completion 2010-11 147 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00911313

    Letrozole or Combined Metformin Clomiphene Citrate (CC) for Women With CC Resistant Polycystic Ovary Syndrome

    Not yet reported Mansoura University 250 participants Est. completion 2009-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00913367

    Efficacy/Safety Study of Amaryl®M 1/500 mg Twice Daily Versus Amaryl® 4 mg Both in Combination With Lantus® in Type 2 Diabetes Mellitus

    Not yet reported Handok Inc. 110 participants Est. completion 2010-11 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00915772

    Treatment of Type 2 Diabetes With Linagliptin 2.5 mg Bid + Metformin 500 or 1000 mg Bid and Metformin 1000 mg Bid

    Not yet reported Boehringer Ingelheim 567 participants 112 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00918138

    Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg

    Not yet reported AstraZeneca 219 participants Est. completion 2010-05 21 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00922194

    Metformin in Overweight Type 2 Diabetes Mellitus

    Not yet reported Era's Lucknow Medical College 102 participants Est. completion 2008-12 1 site
    Type 2 diabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT00924534

    A Safety PK/PD Study of SLV337 in Patients With Type 2 Diabetes

    Not yet reported Abbott Products 61 participants Est. completion 2010-12 12 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00924573

    Comparative Study of HOE490 O (Glimepiride and Metformin) Compared With Placebo on Top of Glimepiride

    Not yet reported Sanofi 189 participants Est. completion 2010-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00929201

    Sitagliptin/Metformin Fed Bioequivalence Study (0431A-080)

    Not yet reported Merck Sharp & Dohme LLC 61 participants Est. completion 2008-05
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00929539

    Safety and Efficacy Study of JTT-130 in Obese Type 2 Diabetic Patients

    Not yet reported Akros Pharma Inc. 496 participants Est. completion 2010-07 62 sites
    Other conditions: Type II Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00930579

    Pre-Surgical Study: Effect of Metformin on Breast Cancer Proliferation

    Not yet reported Columbia University 35 participants Est. completion 2017-01-09 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00933309

    The Impact of Obesity and Obesity Treatments on Breast Cancer

    Not yet reported M.D. Anderson Cancer Center 25 participants Est. completion 2012-08 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00934323

    Dose Proportionality Study About Amaryl M Slow Release (SR) 1/500 mg

    Not yet reported Handok Inc. 33 participants Est. completion 2009-04 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00934570

    Activity and Metformin Intervention in Obese Adolescents

    Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 60 participants Est. completion 2012-05 1 site
    Type 2 diabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT00934817

    Dose Proportionality Study Comparing Amaryl-M 1/500 mg and Amaryl-M 2/500 mg

    Not yet reported Handok Inc. 36 participants Est. completion 2007-08
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT00935805

    Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy

    Hospital de Clinicas de Porto Alegre 124 participants Est. completion 2012-07 1 site
    Other conditions: Diabetes Mellitus, Arterial Hypertension
    View official trial listing →
  • Completed NCT NCT00940472

    Study on DMMET-01 Versus Metformin on Improvement of Metabolic Control in Naive Type 2 Diabetes Patients

    Not yet reported, Not yet reported Laboratorios Silanes S.A. de C.V. 20 participants 1 site
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT00940797

    Effect of DMMET-01 on Insulin Sensitivity in Naive Type 2 Diabetes Patients (CLAMP)

    Not yet reported Laboratorios Silanes S.A. de C.V. 20 participants 1 site
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT00941148

    Beta-Cell Function of Insulin Glargine Compared to Neutral Protamine Hagedorn (NPH) Insuline and to Insulin Detemir in Combination With Metformin

    Not yet reported ikfe-CRO GmbH 30 participants Est. completion 2009-03 1 site
    Other conditions: Type 2 Diabetic Patients, Insufficient Metabolic Control, OAD Treatment
    View official trial listing →
  • Completed NCT NCT00941161

    Effect of Oral Combination Therapy in a Single Dosage Form in Patients With Type 2 Diabetes Mellitus

    Not yet reported Laboratorios Silanes S.A. de C.V. 28 participants 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00941239

    Tolerability and Pharmacokinetics of Metformin and Metformin Extended Release (ER)

    Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2007-02 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT00941382

    Sibutramine-metformin Combination Versus Sibutramine and Metformin Monotherapy in Obese Patients

    Not yet reported Laboratorios Silanes S.A. de C.V. 60 participants Est. completion 2009-09 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT00942123

    Study On the Role of Mitochondrial Dysfunction in the Pathogenesis of Metformin-associated Lactic Acidosis

    Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 10 participants Est. completion 2011-10 1 site
    Other conditions: Lactic Acidosis, Metformin
    View official trial listing →
  • Completed NCT NCT00942188

    A Study of LY2189102 in Patients With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 106 participants Est. completion 2010-11 18 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00942318

    Efficacy of Continuous Subcutaneous Insulin Infusion Versus Basal-bolus Multiple Daily Injections Regimen in Type 2 Diabetes

    Not yet reported University Hospital, Toulouse 52 participants Est. completion 2013-02 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00944346

    Study to Evaluate the Bioequivalence of a Test Tablet Formulation of Metformin HCl (1000 mg), Compared to an Equivalent Dose of a Commercially Available Reference Drug Product (Glucophage®, Bristol-Myers Squibb Company) in Fed, Healthy, Adult Subjects

    Not yet reported Torrent Pharmaceuticals Limited 1 site
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT00947557

    Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background Therapy With Glimepiride With or Without Metformin

    Not yet reported Forest Laboratories 677 participants 147 sites
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Suspended NCT NCT00948324

    Effect of Intensive Therapy Associated With CSII on β-cell Function With Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 400 participants Est. completion 2021-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00948402

    PED/PEA-15 Protein, PCOS, Obesity, Insulin Sensitivity Indexes, Metformin, Oral Contraceptives

    Not yet reported Federico II University 20 participants Est. completion 2009-01 Stand-alone
    Other conditions: Polycystic Ovarian Syndrome, Insulin Sensitivity
    View official trial listing →
  • Completed NCT NCT00951899

    The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics

    Not yet reported Mayo Clinic 38 participants Est. completion 2012-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00953355

    Metformin and Folate Supplementation in Polycystic Ovary Syndrome (PCOS) Patients

    Not yet reported University Magna Graecia 50 participants Est. completion 2007-05 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Anovulation
    View official trial listing →
  • Completed NCT NCT00959101

    Comparison of Repaglinide and Metformin Combination Tablet Versus Repaglinide and Metformin as Separate Tablets in Healthy Volunteers

    Not yet reported Novo Nordisk A/S 42 participants Est. completion 2009-10 1 site Stand-alone
    Other conditions: Diabetes, Healthy
    View official trial listing →
  • Completed NCT NCT00960076

    An 18 Week Efficacy and Safety Study of Saxagliptin and Metformin XR Combination in Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 282 participants Est. completion 2010-10 35 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00960661

    A Trial Comparing Two Therapies: Basal Insulin/Glargine, Exenatide and Metformin Therapy (BET) or Basal Insulin/Glargine, Bolus Insulin Lispro and Metformin Therapy (BBT) in Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 1036 participants Est. completion 2012-08 95 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00961480

    A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Co-administration of Sitagliptin and Metformin as Individual Tablets (0431A-095)

    Not yet reported Merck Sharp & Dohme LLC 24 participants Est. completion 2007-11 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00961857

    A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Concomitant Administration of Sitagliptin and Metformin as Individual Tablets (0431A-048)

    Not yet reported Merck Sharp & Dohme LLC 48 participants Est. completion 2006-01-01 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00961909

    A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus

    Not yet reported Hoffmann-La Roche 122 participants Est. completion 2010-10 6 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00964184

    Phenotypic and Genetic Correlates of Diabetes (Non-Type 1) in Young Non-Obese Asian Indians in North India and A Study to Evaluate the Efficacy of Sitagliptin (DPP-4 Inhibitor) in a Sub-group of the Study Population

    Not yet reported Diabetes Foundation, India 133 participants Est. completion 2015-07 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00965549

    Comparison of a Basal Plus One Insulin Regimen With a Biphasic Insulin Regimen in Type 2 Diabetes Patients

    Not yet reported Sanofi 463 participants Est. completion 2012-12 74 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00965991

    Metformin Compared to Glyburide in Gestational Diabetes

    Not yet reported University of New Mexico 149 participants Est. completion 2023-08 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT00968812

    CANagliflozin Treatment And Trial Analysis-Sulfonylurea (CANTATA-SU) SGLT2 Add-on to Metformin Versus Glimepiride

    Not yet reported Janssen Research & Development, LLC 1452 participants Est. completion 2013-01 138 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00969566

    Predictive Parameters for Efficacy of Sitagliptin and Metformin Combination

    Not yet reported Seoul National University Bundang Hospital 150 participants Est. completion 2011-07 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00969631

    Combined Metformin and Clomiphene Citrate (CC) or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome (PCOS)

    Not yet reported Mansoura University 282 participants Est. completion 2009-02 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT00970528

    Glucose Reduction by Early Acarbose Treatment in Basal Insulin

    Not yet reported Bayer 124 participants Est. completion 2012-03 11 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00970593

    Study Evaluating Safety, Tolerability, And Action Of OAP-189 In Subjects With Type 2 Diabetes On Metformin

    Not yet reported Pfizer 92 participants Est. completion 2011-07-25 2 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00971243

    Efficacy and Safety of MP-513 in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Tanabe Pharma Corporation 448 participants Est. completion 2011-04 44 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00971295

    Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Metformin in Healthy Volunteers

    Not yet reported Bial - Portela C S.A. 20 participants Est. completion 2008-09 1 site Stand-alone
    Other conditions: Neuropathic Pain
    View official trial listing →
  • Completed NCT NCT00971659

    Adjunctive Therapy of Exenatide or Sitagliptin to Insulin Glargine in Type 2 Diabetes

    Not yet reported Profil Institut für Stoffwechselforschung GmbH 48 participants Est. completion 2008-11 1 site Mixed
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00972283

    Comparison of NN1250 With Insulin Glargine Plus Insulin Aspart With/Without Metformin and With/Without Pioglitazone in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 1006 participants Est. completion 2010-10-28 136 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00975052

    A Study of the Effects of Sitagliptin (MK0431) and Metformin on Incretin Hormone Concentrations (0431-050)(COMPLETED)

    Not yet reported Merck Sharp & Dohme LLC 16 participants Est. completion 2006-03 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00975065

    Galvus on Met Phase 4 Study : Study to Evaluate the Efficacy and Safety of Early Combination of Vildagliptin and Metformin in Patients With Type 2 Diabetes Mellitus

    Not yet reported Handok Inc. 266 participants Est. completion 2012-04 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00976937

    24-week Study Comparing Lixisenatide to Sitagliptin as add-on to Metformin in Obese Type 2 Diabetic Patients Younger Than 50 Years

    Not yet reported Sanofi 319 participants Est. completion 2011-03 92 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00978263

    Comparison of Glargine and Oral Antidiabetic Drugs (OADs) in Newly Diagnosed Type 2 Diabetes

    Not yet reported Chongqing Medical University 47 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT00984490

    Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery

    Not yet reported Vanderbilt-Ingram Cancer Center 5 participants Est. completion 2011-07 3 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT00984867

    Dapagliflozin DPPIV Inhibitor add-on Study

    Not yet reported AstraZeneca 833 participants Est. completion 2011-09 88 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00986401

    Safety and Tolerability of Trospium Chloride and Metformin Hydrochloride in Healthy Subjects

    Not yet reported Allergan 44 participants Est. completion 2009-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT00988078

    Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome

    Not yet reported Federal University of São Paulo 90 participants Est. completion 2013-12 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Suspended NCT NCT00990444

    A Two Part Study of Peroral Insulin in Type 2 Diabetes

    Not yet reported, Not yet reported Bows Pharmaceuticals AG 32 participants Est. completion 2010-12 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT00991055

    Comparison of the Efficacy and Safety Between Pioglitazone and Placebo Added to Combination Therapy in Type 2 Diabetes

    Not yet reported National Cheng-Kung University Hospital 40 participants Est. completion 2010-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00993187

    Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)

    Not yet reported Merck Sharp & Dohme LLC 292 participants Est. completion 2013-10-29 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00994812

    The Effects of Metformin on Pregnancy and Miscarriage Rates in Polycystic Ovary Syndrome (PCOS)

    Not yet reported University of Oulu 326 participants Est. completion 2009-12 5 sites Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Miscarriage, Infertility, Toxemia, Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT00995345

    Safety and Efficacy of Once-Daily KRP-104 in Type 2 Diabetics With Inadequate Glycemic Control on Metformin Alone

    Not yet reported ActivX Biosciences, Inc. 403 participants Est. completion 2011-01 45 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00995787

    Safety and Tolerability of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients Treated With Metformin and Sulfonylurea

    Not yet reported AstraZeneca 75 participants Est. completion 2010-02 1 site
    Other conditions: Type II Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00996658

    Linagliptin Versus Placebo in Type 2 Diabetic Patients With Inadequate Glycaemic Control on Metformin in Combination With Pioglitazone

    Not yet reported Boehringer Ingelheim 278 participants 52 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00997152

    Efficacy and Safety Study of JTT-654 in Type 2 Diabetic Patients

    Not yet reported Akros Pharma Inc. 152 participants Est. completion 2010-04 42 sites
    Other conditions: Type II Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT00998686

    Safety and Efficacy Study of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

    Not yet reported Phenomix 650 participants Est. completion 2011-11 44 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01001962

    Double Blind Placebo Study of JARDIANCE® (Empagliflozin) in Prehypertensives Type II Diabetics

    Not yet reported Aristotle University Of Thessaloniki 1054 participants Est. completion 2020-01 1 site
    Other conditions: Hypertension, Type II Diabetes
    View official trial listing →
  • Completed NCT NCT01002807

    Bioavailability Study of Fixed Dose Combination (FDC) Formulations of Dapagliflozin and Metformin XR Versus Individual Component Coadministered to Healthy Subjects in a Fasted State

    Not yet reported AstraZeneca 15 participants Est. completion 2010-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01003184

    Efficacy of Once-Weekly Exenatide Versus Once or Twice Daily Insulin Detemir in Patients With Type 2 Diabetes

    Not yet reported AstraZeneca 222 participants Est. completion 2011-12 34 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01003483

    Metformin Versus Orlistat in Obese Polycystic Ovary Syndrome (PCOS) Patients

    Not yet reported Yazd Research & Clinical Center for Infertility 80 participants Est. completion 2009-11 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT01005160

    Drug Interaction Between CKD-501 and Metformin

    Not yet reported Chong Kun Dang Pharmaceutical 24 participants Est. completion 2010-02 Stand-alone
    Other conditions: Healthy Male Volunteers
    View official trial listing →
  • Completed NCT NCT01006590

    Efficacy and Tolerability of Saxagliptin add-on Compared to Uptitration of Metformin in Patients With Type 2 Diabetes

    Not yet reported AstraZeneca 286 participants Est. completion 2010-12 51 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01006603

    Saxagliptin Compared to Glimepiride in Elderly Type 2 Diabetes Patients, With Inadequate Glycemic Control on Metformin

    Not yet reported AstraZeneca 957 participants Est. completion 2012-06 131 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01008046

    N-acetyl Cysteine and Clomiphene Citrate or Metformin and Clomiphene Citrate for Women With CC Resistant Polycystic Ovary Syndrome (PCOS).

    Not yet reported Mansoura University 192 participants Est. completion 2009-06 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01009580

    Comparison of NN5401 With Biphasic Insulin Aspart 30 in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 447 participants Est. completion 2010-08-23 53 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01011868

    Efficacy and Safety of BI 10773 in Combination With Insulin in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 494 participants 99 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01012037

    Linagliptin 2.5 mg Twice Daily Versus 5 mg Once Daily as add-on Therapy to Twice Daily Metformin in Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 491 participants 84 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01013051

    Effect of Gastric Bypass on the Absorption of Metformin

    University of Alberta 34 participants Est. completion 2010-12 1 site
    Other conditions: Obesity, Gastric Bypass
    View official trial listing →
  • Completed NCT NCT01017302

    A Study With RO5095932 in Patients With Type 2 Diabetes on Stable Metformin Therapy.

    Not yet reported Hoffmann-La Roche 32 participants Est. completion 2011-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01020123

    Evaluate Efficacy, Safety and Tolerability of AZD1656 as Add-on Treatment to Metformin in Type 2 Diabetes Mellitus (TD2M) Patients

    Not yet reported AstraZeneca 530 participants Est. completion 2011-02 77 sites
    Other conditions: Type II Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01021579

    Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study

    Not yet reported Fasa University of Medical Sciences 84 participants Est. completion 2009-11 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01022658

    INSUlin Regimens and VASCular Functions

    Not yet reported Assistance Publique - Hôpitaux de Paris 42 participants Est. completion 2011-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01023581

    Efficacy and Safety of Alogliptin Plus Metformin in Patients With Type 2 Diabetes

    Not yet reported Takeda 784 participants Est. completion 2011-06 201 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01024244

    A Study of LY2599506 in Patients With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 78 participants Est. completion 2010-07 16 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01025765

    The Effects of Oral Hypoglycemic Agents on Chronic Hepatitis C Patients Receiving Peg-Intron Plus Ribavirin

    Not yet reported National Taiwan University Hospital 80 participants Est. completion 2012-12 1 site Stand-alone
    Other conditions: Chronic Hepatitis C
    View official trial listing →
  • Completed NCT NCT01028391

    30-Week Extension to an Initial Combination Study (24 Weeks in Duration) of Sitagliptin With Pioglitazone (0431-064)

    Not yet reported Merck Sharp & Dohme LLC 317 participants Est. completion 2009-01-01 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01029795

    A Study of LY2599506 (Oral Agent Medication: Glucokinase Activator 1) in Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 38 participants Est. completion 2010-06 16 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01033773

    Stop Emergency Room Visits for Hyperglycemia Project - District of Columbia (DC)

    Not yet reported Medstar Health Research Institute 86 participants Est. completion 2009-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01034111

    A Local Experiential Study With Sitagliptin (an Antihyperglycemic Drug) in 30 Patients With Type 2 Diabetes Mellitus (0431-178)

    Not yet reported Merck Sharp & Dohme LLC 30 participants Est. completion 2010-10-04 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01035528

    Can Insulin Glargine Improve Myocardial Function in Patients With T2D and Coronary Artery Disease (CAD)

    Not yet reported Munich Municipal Hospital 32 participants Est. completion 2010-08 1 site
    Cardiovascular diseaseType 2 diabetes
    View official trial listing →
  • Completed NCT NCT01037660

    Effects of Lipemia and Metformin on Endothelial Function

    Not yet reported Boston University 139 participants Est. completion 2016-12-01 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT01037842

    Effect of Combination of Mitiglinide and Metformin on Glycemic Control in Patients With Type 2 Diabetes Mellitus

    Not yet reported Seoul National University Hospital 145 participants Est. completion 2008-05 13 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01043965

    Myocardial Perfusion in Type 2 Diabetes

    Not yet reported, Not yet reported University of Sao Paulo General Hospital 61 participants Est. completion 2009-08
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01045707

    Comparison of NN5401 Versus Insulin Glargine, Both Combined With Metformin Treatment, in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 530 participants Est. completion 2010-10 92 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01046032

    Metformin Treatment Before in Vitro Fertilization (IVF) in Women With Ultrasound Evidence of Polycystic Ovaries

    Not yet reported University of Oxford 134 participants Est. completion 2009-05 3 sites
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01046422

    Safety Study of BMS-770767 in Subjects With Type 2 Diabetes

    Not yet reported Bristol-Myers Squibb 76 participants Est. completion 2011-01 18 sites Stand-alone
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Status unknown NCT NCT01046500

    Myo-inositol Versus Metformin Administration in Post-menopausal Women With Metabolic Syndrome

    Not yet reported University of Messina 100 participants Est. completion 2014-12 1 site
    Metabolic syndrome
    View official trial listing →
  • Terminated NCT NCT01051011

    A Study to Compare Taspoglutide and Insulin Glargine in Insulin-Naïve Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin and Sulfonylurea Combination Therapy

    Not yet reported Hoffmann-La Roche 370 participants Est. completion 2010-12 56 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01055691

    A Study Comparing the Amount of Metformin and After Taking a Combination Tablet vs. Separate Tablets

    Not yet reported AstraZeneca 120 participants Est. completion 2010-04 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT01059825

    Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016)

    Not yet reported Merck Sharp & Dohme LLC 375 participants Est. completion 2011-01-20 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01064687

    A Study in Participants With Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 978 participants Est. completion 2012-05 89 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01065298

    Efficacy Of Autologous Bone Marrow Derived Stem Cell Transplantation In Patients With Type 2 Diabetes Mellitus-2

    Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2011-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01065766

    Sitagliptin/Metformin (JANUMET) Re-examination Study (0431A-182)

    Merck Sharp & Dohme LLC 4065 participants Est. completion 2013-05
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01066715

    Safety and Efficacy of XOMA 052 in Subjects With Type 2 Diabetes Mellitus on Stable Metformin Monotherapy

    Not yet reported XOMA (US) LLC 421 participants Est. completion 2011-07 67 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01068652

    Effect of Different Insulin Administrations, All in Combination With Metformin, on Glycaemic Control in Subjects With Type 2 Diabetes Inadequately Controlled by Oral Anti-diabetic Drugs

    Not yet reported Novo Nordisk A/S 403 participants Est. completion 2012-05 19 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01068717

    Bioequivalence Study of 2.5-mg Saxagliptin and 500-mg Glucophage in Tablets and a Fixed-dose Combination Tablet in Healthy Participants

    Not yet reported AstraZeneca 27 participants Est. completion 2010-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01068730

    Bioequivalence Study of 500 mg and 1000 mg Glucophage (Metformin) Tablets in Healthy Subjects

    Not yet reported AstraZeneca 28 participants Est. completion 2010-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01068743

    Bioequivalence Study of Fixed Dose Combination of 2.5 mg Saxagliptin/850 mg Metformin Tablet Relative to 2.5 mg Onglyza and 850 mg Glucophage Tablets Co-Administered

    Not yet reported AstraZeneca 24 participants Est. completion 2010-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01068860

    To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies

    Not yet reported Novartis 246 participants Est. completion 2010-08 52 sites Stand-alone
    Type 2 diabetesPrediabetes
    View official trial listing →
  • Terminated NCT NCT01069965

    Safety and Efficacy of BGP-15 in Patients With Type 2 Diabetes Mellitus

    Not yet reported N-Gene Research Laboratories, Inc. 196 participants Est. completion 2011-10 30 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01070160

    Endometrial Effects of Metformin Action in Women With Polycystic Ovarian Syndrome (PCOS)

    Yale University 14 participants Est. completion 2013-07 1 site
    Other conditions: Polycystic Ovarian Syndrome
    View official trial listing →
  • Completed NCT NCT01071850

    A Study to Evaluate the Effect of ASP1941 in Adult Patients With Type 2 Diabetes Mellitus

    Not yet reported Astellas Pharma Inc 412 participants Est. completion 2011-04-11 59 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01075282

    A Study in Participants With Type 2 Diabetes Mellitus (AWARD-2)

    Not yet reported Eli Lilly and Company 810 participants Est. completion 2012-11 78 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01076075

    A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229)

    Not yet reported Merck Sharp & Dohme LLC 427 participants Est. completion 2012-01-19 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01076088

    Safety and Efficacy of Co-Administration of Sitagliptin and Metformin in China (MK-0431-121)

    Not yet reported Merck Sharp & Dohme LLC 744 participants Est. completion 2012-12-24 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01077323

    A Retrospective Cohort Study of Acute Pancreatitis in Relation to Use of Exenatide and Other Antidiabetic Agents

    AstraZeneca 363766 participants Est. completion 2008-03 1 site
    Type 2 diabetes Other conditions: Healthy Subjects (Treated With no Diabetes Therapies)
    View official trial listing →
  • Completed NCT NCT01077479

    Metformin in Preventing Androgen Deprivation Therapy Induced Insulin Resistance and Metabolic Syndrome

    Not yet reported Western Sydney Local Health District 28 participants Est. completion 2013-06 1 site Stand-alone
    Metabolic syndrome Other conditions: Hypercholesterolemia
    View official trial listing →
  • Completed NCT NCT01082120

    Investigate the Effect of AZD1656 on the Pharmacokinetics of Pioglitazone and Vice Versa in Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 28 participants Est. completion 2010-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01083212

    To Evaluate the Effect of Gemfibrozil on the Pharmacokinetics and Pharmacodynamics of a Single Dose of AZD1656

    Not yet reported AstraZeneca 19 participants Est. completion 2010-06 3 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01084005

    Efficacy and Safety of Linagliptin in Elderly Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 241 participants 34 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01084486

    Effect of Treatment With Insulin Sensitizer on Arterial Properties, Metabolic Parameters and Liver Function in Patients With Nonalcoholic Fatty Liver Disease

    Not yet reported, Not yet reported Wolfson Medical Center 1 site Stand-alone
    MASLD
    View official trial listing →
  • Completed NCT NCT01087567

    INSPIRE Diabetes Study: Basal Bolus Insulin as Primary Treatment of Type 2 Diabetes

    Not yet reported Ohio University 23 participants Est. completion 2014-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01087866

    Metformin Versus Insulin in the Treatment of Gestational Diabetes Mellitus

    Not yet reported, Not yet reported University of Oulu 97 participants Est. completion 2009-10 1 site Stand-alone
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01087983

    Lapatinib With Sirolimus or Metformin

    Not yet reported M.D. Anderson Cancer Center 111 participants Est. completion 2015-09 1 site Stand-alone
    Other conditions: Advanced Cancers
    View official trial listing →
  • Completed NCT NCT01089166

    Study to Compare the Bioavailability of Extended Release Metformin HCl Tablet Versus Glucophage XR® Tablets in Healthy Human Volunteers Under Fasting Condition

    Not yet reported Torrent Pharmaceuticals Limited 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01089179

    Bioequivalence Study of Metformin Hydrochloride Extended Release 500 mg Tablet Versus Glucophage XR® 500 mg Tablet in Healthy Volunteers Under Fed Conditions

    Not yet reported Torrent Pharmaceuticals Limited 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01089192

    Bioequivalence Study of Metformin Hydrochloride Extended Release 750 mg Tablets Versus Glucophage XR® 750 mg Tablet in Healthy Volunteers Under Fasting Conditions.

    Not yet reported Torrent Pharmaceuticals Limited 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01089205

    Bioequivalence Study of Metformin Hydrochloride Extended Release 750 mg Tablets Versus Glucophage XR® 750 mg Tablet in Healthy Volunteers Under Fed Conditions.

    Not yet reported Torrent Pharmaceuticals Limited Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01089790

    Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus Receiving Background Treatment With Glimepiride Alone or in Combination With Metformin or With Pioglitazone Alone

    Not yet reported Forest Laboratories 141 participants 149 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01093794

    Bioequivalence Study of Sitagliptin/Metformin Combination Tablet (MK0431A-122)

    Not yet reported Merck Sharp & Dohme LLC 28 participants Est. completion 2010-06 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01095653

    A Phase III Study of BMS-512148 (Dapagliflozin) in Asian Patients With Type 2 Diabetes Who Are Not Well Controlled With Diet and Exercise

    Not yet reported AstraZeneca 1179 participants Est. completion 2012-03 39 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01095666

    A Phase III Study of BMS-512148 (Dapagliflozin) in Asian Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone

    Not yet reported AstraZeneca 1484 participants Est. completion 2013-03 33 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01095822

    Effects of Valsartan and Aliskiren on Hemostatic Indices in Hypertensive Diabetics

    Not yet reported HeartDrug Research LLC 50 participants Est. completion 2011-03 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01095991

    Investigate the Effect of AZD1656 on the Pharmacokinetics of Sitagliptin in Patients With Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 12 participants Est. completion 2010-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01096940

    Study To Assess the Pharmacokinetics of AZD1656 During Coadministration With Simvastatin

    Not yet reported AstraZeneca 44 participants Est. completion 2010-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01099137

    Effect of Vildagliptin in Type 2 Diabetes Treated With Sulphonylurea and Metformin

    Not yet reported Seoul National University Bundang Hospital 344 participants Est. completion 2013-05 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01099618

    Ketosis-Prone Diabetes Mellitus (KPDM): Metformin Versus Sitagliptin Treatment

    Not yet reported Dawn Smiley MD 48 participants Est. completion 2014-08 1 site
    Other conditions: Ketosis Prone Diabetes, Diabetes Ketoacidosis, Hyperglycemia
    View official trial listing →
  • Status unknown NCT NCT01101204

    The Effects of Hypolipemic and Antidiabetic Treatment on Cytokines

    Not yet reported Medical University of Silesia 200 participants Est. completion 2012-12 1 site
    Other conditions: Diabetes, Dyslipidemia, Inflammation, Cytokines
    View official trial listing →
  • Completed NCT NCT01101438

    A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer

    Not yet reported Canadian Cancer Trials Group 3649 participants Est. completion 2023-08-18 344 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01103609

    Investigate the Effect of AZD1656 on the Pharmacokinetics and Pharmacodynamics of Warfarin in Type 2 Diabetes Mellitus (T2DM) Patients

    Not yet reported AstraZeneca 16 participants Est. completion 2010-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01103622

    Investigate the Effect of AZD1656 on the Pharmacokinetics of Digoxin in Type 2 Diabetes Mellitus Patients

    Not yet reported AstraZeneca 20 participants Est. completion 2010-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01105429

    Single Ascending Dose Study of BMS-820132 in Patients With Type 2 Diabetes

    Not yet reported Bristol-Myers Squibb 56 participants Est. completion 2010-10 3 sites
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT01106131

    Efficacy and Safety of CKD-501 Versus Pioglitazone When Added to Metformin

    Not yet reported Chong Kun Dang Pharmaceutical 253 participants Est. completion 2012-11 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01106625

    The CANTATA-MSU Trial (CANagliflozin Treatment And Trial Analysis - Metformin and SUlphonylurea)

    Not yet reported Janssen Research & Development, LLC 469 participants Est. completion 2012-04 76 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01106651

    A Safety and Efficacy Study of Canagliflozin in Older Patients (55 to 80 Years of Age) With Type 2 Diabetes Mellitus

    Not yet reported Janssen Research & Development, LLC 716 participants Est. completion 2013-05 86 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01106677

    The CANTATA-D Trial (CANagliflozin Treatment and Trial Analysis - DPP-4 Inhibitor Comparator Trial)

    Not yet reported Janssen Research & Development, LLC 1284 participants Est. completion 2012-05 125 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01106690

    The CANTATA-MP Trial (CANagliflozin Treatment and Trial Analysis - Metformin and Pioglitazone)

    Not yet reported Janssen Research & Development, LLC 344 participants Est. completion 2012-07 83 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01107717

    Durability of Combination Therapy With Exenatide/Pioglitazone/Metformin vs. Conventional Therapy in New Onset T2DM

    Not yet reported The University of Texas Health Science Center at San Antonio 318 participants Est. completion 2023-02-03 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Withdrawn NCT NCT01107808

    Calcium, Vitamin D and Metformin to Treat Insulin Resistance in Obese African American Adolescent Females

    Not yet reported University of Alabama at Birmingham Est. completion 2011-03 Stand-alone
    Other conditions: Insulin Resistance, Insulin Sensitivity, Obesity, Vitamin D Deficiency
    View official trial listing →
  • Completed NCT NCT01111955

    Safety Study of BMS-823778 in Subjects With Type 2 Diabetes

    Not yet reported Bristol-Myers Squibb 62 participants Est. completion 2011-01 14 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01115140

    Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women

    Not yet reported University Magna Graecia 50 participants Est. completion 2011-05 1 site Stand-alone
    Other conditions: Pregnancy, Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01117103

    A Prospective, Observational Study to Assess and Evaluate the Use of Glucophage XR Therapy in the Management of Patients With Type 2 Diabetes

    Merck KGaA, Darmstadt, Germany 3592 participants Est. completion 2009-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01117350

    Efficacy Assessment of Insulin Glargine Versus LiraglutidE After Oral Agents Failure

    Not yet reported Sanofi 978 participants Est. completion 2013-03 136 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01117584

    A Study to Evaluate the Effect of ASP1941 in Combination With Metformin in Adult Patients With Type 2 Diabetes Mellitus

    Not yet reported Astellas Pharma Inc 343 participants Est. completion 2011-04-01 44 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01119846

    A Study in Type 2 Diabetics of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics

    Not yet reported GlaxoSmithKline 100 participants Est. completion 2010-03-19 7 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01123980

    Comparison of the Blood Sugar Lowering Effect of Biphasic Insulin Aspart 30 and Insulin Glargine Both Combined With Metformin and Glimepiride in Chinese and Japanese Subjects With Type 2 Diabetes New to Insulin Treatment

    Not yet reported Novo Nordisk A/S 521 participants Est. completion 2011-06 34 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01125150

    Spectroscopic and Colorimetric Analysis of Acanthosis Nigricans in Patients With Hyperinsulinemia

    Henry Ford Health System 9 participants Est. completion 2012-06 1 site
    Other conditions: Acanthosis Nigricans, Hyperinsulinemia, Spectroscopic Analysis
    View official trial listing →
  • Completed NCT NCT01126580

    A Study in Participants With Type 2 Diabetes Mellitus (AWARD-3)

    Not yet reported Eli Lilly and Company 807 participants Est. completion 2012-06 91 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01128621

    A Study in Type 2 Diabetic Subjects on Stable Metformin Therapy to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Co-administering Single and Multiple Oral Doses of GSK1292263

    Not yet reported GlaxoSmithKline 66 participants Est. completion 2010-04-12 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01131182

    Study of Sitagliptin Treatment in Patients With Type 2 Diabetes During Ramadan (0431-263)

    Not yet reported Merck Sharp & Dohme LLC 1147 participants Est. completion 2010-11-04 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01135433

    A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Metformin in Type 2 Diabetic Patients

    Not yet reported Astellas Pharma Inc 168 participants Est. completion 2011-11-28 7 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01136512

    Metformin Use and Vitamin B12 Deficiency

    Northwell Health 89 participants Est. completion 2008-12 1 site
    Type 2 diabetes Other conditions: Vitamin B12 Deficiency
    View official trial listing →
  • Completed NCT NCT01137812

    The CANTATA-D2 Trial (CANagliflozin Treatment And Trial Analysis - DPP-4 Inhibitor Second Comparator Trial)

    Not yet reported Janssen Research & Development, LLC 756 participants Est. completion 2012-03 184 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01140438

    Treatment of Latent Autoimmune Diabetes of the Adult

    Not yet reported Norwegian University of Science and Technology 64 participants Est. completion 2018-11 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01144728

    Initiation and Titration of Amaryl

    Not yet reported Sanofi 172 participants Est. completion 2010-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01144975

    Study of the Safety and Biologic Activity of XOMA 052 in Subjects With Type 2 Diabetes Mellitus

    Not yet reported XOMA (US) LLC 76 participants Est. completion 2011-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01154348

    Study to Assess Safety and Pharmacokinetics of Double-Blind S-707106 Alone and in Combination With Open-Label Metformin in Patients With Type 2 Diabetes Mellitus

    Not yet reported Shionogi 34 participants Est. completion 2010-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01156246

    Study to Assess the Effect of Food on Combination Dapagliflozin/Metformin Tablet in Healthy Volunteers

    Not yet reported AstraZeneca 18 participants Est. completion 2010-08 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01156597

    Effects of Pioglitazone on High-density Lipoprotein (HDL) Function in Persons With Diabetes

    Not yet reported University of Miami 30 participants Est. completion 2010-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01159600

    Efficacy and Safety Study With Empagliflozin (BI 10773) vs. Placebo as add-on to Metformin or Metformin Plus Sulfonylurea Over 24 Weeks in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 1504 participants 148 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01160042

    Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fasting Condition

    Not yet reported Dr. Reddy's Laboratories Limited 54 participants Est. completion 2005-04 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01160068

    Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fed Condition

    Not yet reported Dr. Reddy's Laboratories Limited 50 participants Est. completion 2005-05 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT01162772

    Influence of DPP-4 on Inflammatory Parameters in Diabetics: Gender Aspects

    Medical University of Vienna 80 participants 1 site
    Type 2 diabetes Other conditions: Cardiovascular Risk, Endothelial Dysfunction
    View official trial listing →
  • Terminated NCT NCT01167738

    Combination Chemotherapy With or Without Metformin Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer

    Not yet reported IRCCS San Raffaele 60 participants Est. completion 2015-04 1 site Stand-alone
    Other conditions: Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT01169090

    A Study Comparing the Safety, Tolerance, and Efficacy of Various Doses of SK-0403 Versus Placebo and Sitagliptin 100 mg in Patients Not Well-Controlled on Metformin Therapy

    Not yet reported Kowa Research Institute, Inc. 620 participants Est. completion 2011-08 40 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01169779

    Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled by Metformin

    Not yet reported Sanofi 391 participants Est. completion 2011-12 35 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01171456

    Early Intervention for Gestational Diabetes

    Not yet reported Intermountain Health Care, Inc. Est. completion 2010-07 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01175473

    Effects of Lixisenatide Compared to Liraglutide on the Postprandial Plasma Glucose in Patients With Type 2 Diabetes

    Not yet reported Sanofi 148 participants Est. completion 2010-11 7 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01175824

    Comparison of the Efficacy and Safety of Two Insulin Intensification Strategies

    Not yet reported Eli Lilly and Company 478 participants Est. completion 2012-11 18 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01177709

    Metformin for Weight Loss in Schizophrenia

    Not yet reported Nathan Kline Institute for Psychiatric Research 12 participants Est. completion 2011-04 1 site Stand-alone
    Other conditions: Schizophrenia, Obesity
    View official trial listing →
  • Completed NCT NCT01181674

    Remission Evaluation of Metabolic Interventions in Type 2 Diabetes (REMIT Pilot Trial)

    Not yet reported Population Health Research Institute 83 participants Est. completion 2015-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01187849

    Metformin to Prevent Metabolic Complications in Glucocorticoid Excess

    Not yet reported University Hospital, Basel, Switzerland 29 participants Est. completion 2015-12 1 site
    Other conditions: Patients With Glucocorticoid Treatment
    View official trial listing →
  • Completed NCT NCT01192139

    Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin XR Tablet (Manufactured in Mt Vernon, IN) Relative to 5 mg Saxagliptin Tablet and 500 mg Metformin XR Tablet (Manufactured in Evansville, IN)

    Not yet reported AstraZeneca 30 participants Est. completion 2009-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01192152

    Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin/1000 mg Metformin XR (Manufactured in Mt Vernon, IN) Relative to 5 mg of Onglyza and 2 × 500 mg Glucophage XR

    Not yet reported AstraZeneca 30 participants Est. completion 2009-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01193296

    Glycemic Holter Study (Continuous Glucose Monitoring) -

    Not yet reported Novartis 36 participants Est. completion 2011-06 7 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01195090

    Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and Sulfonylurea

    Not yet reported Sung-Chen Liu 120 participants Est. completion 2012-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01195259

    Malignancy Meta Analysis for BRL49653

    GlaxoSmithKline 1 participants Est. completion 2010-01
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01196546

    Efficacy and Safety of Combination Therapy of Vildagliptin/Metformin in Patients in Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Novartis 161 participants Est. completion 2011-10 8 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01203111

    Intensive Insulin Glulisine Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Basal Insulin and Oral Glucose-lowering Drugs

    Not yet reported Sanofi 207 participants Est. completion 2012-07 10 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01204294

    Comprehensive Add on Study in Japan

    Not yet reported Boehringer Ingelheim 574 participants Est. completion 2012-01 43 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01204580

    ADIponectin and Asymmetric Dimethylarginine (ADMA) Level in Type-2 Diabetes Patients After 12 Weeks of Treatment With GlimepiRide And Metformin Fixed Dose Combination

    Not yet reported Sanofi 40 participants Est. completion 2012-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01204775

    Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin as Monotherapy in Pediatric Patients With Type 2 Diabetes

    Not yet reported AstraZeneca 26 participants Est. completion 2016-04 16 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01205672

    Evaluation of the Molecular Effects of Metformin on the Endometrium in Patients With Endometrial Cancer

    Not yet reported M.D. Anderson Cancer Center 21 participants Est. completion 2017-05-28 2 sites Stand-alone
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT01206153

    Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients

    Not yet reported Central South University 84 participants Est. completion 2010-03 1 site Stand-alone
    Other conditions: Amenorrhea
    View official trial listing →
  • Status unknown NCT NCT01206647

    Investigation of a Switch From Insulin Therapy to a Metformin & Saxagliptin Combination in Patients With Type 2 Diabetes Mellitus

    Not yet reported ikfe-CRO GmbH 120 participants Est. completion 2011-02 7 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01206712

    Beta Cell Relieving and Cardiovascular Protective Effects of LANTUS Treatment in Type 2 Diabetes Patients

    ikfe-CRO GmbH 106 participants Est. completion 2010-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01208012

    Impact of Liraglutide on Endothelial Function and Microvascular Blood Flow in Type 2 Diabetes Mellitus

    Not yet reported ikfe-CRO GmbH 44 participants Est. completion 2010-11 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01208740

    Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization

    Not yet reported University Magna Graecia 88 participants Est. completion 2011-03 1 site Stand-alone
    Other conditions: Infertility, PCOS, Prognosis for Poor Response
    View official trial listing →
  • Completed NCT NCT01210001

    Efficacy and Safety of Empagliflozin (BI 10773) in Type 2 Diabetes Patients on a Background of Pioglitazone Alone or With Metformin

    Not yet reported Boehringer Ingelheim 499 participants 68 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01210911

    Metformin Combined With Chemotherapy for Pancreatic Cancer

    Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 120 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: Locally Advanced Pancreatic Cancer, Metastatic Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT01211197

    Bioavailability of a Fixed Dose Combination Tablet With Empagliflozin (BI 10773) and Metformin Compared With the Monocomponents and Effect of Food on Bioavailability

    Not yet reported Boehringer Ingelheim 16 participants 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01213563

    Management of Type 2 Diabetes After Gastric Bypass Surgery

    Not yet reported Imperial College London 50 participants Est. completion 2010-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01215032

    Metformin in Castration-Resistant Prostate Cancer

    Not yet reported Massachusetts General Hospital 21 participants Est. completion 2015-01 3 sites Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01215097

    Efficacy and Safety Study of Linagliptin (5 mg Administered Orally Once Daily) Over 24 Weeks in Type 2 Diabetic Patients With Insufficient Glycaemic Control Despite Metformin Therapy

    Not yet reported Boehringer Ingelheim 306 participants Est. completion 2012-04 19 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01215331

    Gestational Diabetes: Insulin or Oral Hypoglycemic Agents?

    Not yet reported Université de Sherbrooke 73 participants Est. completion 2016-05 1 site Stand-alone
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01216397

    Relative Bioavailability of Two Different Batches of a Linagliptin / Metformin Combination Tablet in Healthy Volunteers

    Not yet reported Boehringer Ingelheim 40 participants 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01217073

    A Dose-Range Finding Study in Participants With Type 2 Diabetes (MK-3102-006)

    Not yet reported Merck Sharp & Dohme LLC 685 participants Est. completion 2013-04-01
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01217307

    Metformin to Reduce Heart Failure After Myocardial Infarction

    Not yet reported, Not yet reported University Medical Center Groningen 380 participants Est. completion 2015-10 1 site Stand-alone
    Cardiovascular diseaseHeart failure Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01217892

    Evaluation of Dapagliflozin Taken Twice-daily

    Not yet reported AstraZeneca 400 participants Est. completion 2011-08 55 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01219582

    GLucobay M OBservation Study for Efficacy and Safety in Treatment of Type-2 Diabetes Patients

    Bayer 9364 participants Est. completion 2012-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01221519

    A Relative Bioavailability Study Measuring the Extent and Rate of Absorption of Different Tablet Formulations of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients

    Not yet reported AstraZeneca 20 participants Est. completion 2011-01 1 site
    Type 2 diabetes Other conditions: High Blood Sugar
    View official trial listing →
  • Completed NCT NCT01224366

    Efficacy and Safety of Vildagliptin as add-on Therapy to Insulin in Patients With Type 2 Diabetes Mellitus

    Not yet reported Novartis 448 participants Est. completion 2011-10 66 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01228240

    The Efficacy of Metformin Produced by Pars Mino Co in Comparison With Canadian Apotex Co.

    Not yet reported Zanjan University of Medical Sciences 18 participants Est. completion 2009-09 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01231074

    Reducing Antipsychotic-Induced Weight Gain in Children With Metformin

    Not yet reported Nationwide Children's Hospital 96 participants Est. completion 2013-05 1 site Stand-alone
    Other conditions: Obesity, Weight Gain, Psychotropic Induced Weight Gain
    View official trial listing →
  • Completed NCT NCT01232036

    Clinical Trial to Compare the Pharmacokinetics and Pharmacodynamics After Oral Administration of Glucophage and HL-018

    Not yet reported Asan Medical Center 28 participants Est. completion 2010-10 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01232491

    Impact of Dietary Intervention on Weight Change in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 611 participants Est. completion 2011-11-14 112 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01232946

    Cooperation of Insulin and GLP-1 on Myocardial Glucose Uptake

    Not yet reported Indiana University 30 participants Est. completion 2017-09-08 1 site Mixed
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01233206

    Metformin in High Responder Polycystic Ovary Syndrome (PCOS) Patients Undergoing IVF Cycles

    Not yet reported University Magna Graecia 120 participants Est. completion 2011-01 1 site Stand-alone
    Other conditions: Infertility, Polycystic Ovary Syndrome (PCOS)
    View official trial listing →
  • Completed NCT NCT01233622

    Safety and Efficacy of Galvus as add-on Therapy to Metformin Plus Glimepiride

    Not yet reported Novartis 317 participants Est. completion 2011-11 55 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01234649

    Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)

    Not yet reported Woman's 153 participants Est. completion 2019-06-14 1 site Stand-alone
    Type 2 diabetesMetabolic syndromePrediabetes Other conditions: Gestational Diabetes Mellitus, Disorder of Glucose Regulation
    View official trial listing →
  • Completed NCT NCT01237314

    The Impact of Food on Blood Sugar in People With Type 2 Diabetes

    HealthPartners Institute 46 participants Est. completion 2013-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01237522

    A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers

    Not yet reported University of Southern Denmark 50 participants Est. completion 2010-12 1 site
    Other conditions: Metformin, Organic Cation Transporter 2, Polymorphism,Single Nucleotide
    View official trial listing →
  • Completed NCT NCT01238978

    Phase 4 Study in the Elderly Patients With T2DM

    Not yet reported Novartis 46 participants Est. completion 2011-12 15 sites
    Type 2 diabetes Other conditions: Elderly
    View official trial listing →
  • Completed NCT NCT01240759

    Safety and Efficacy of S-707106 in Subjects With Type 2 Diabetes Mellitus and Inadequate Glycemic Control With Metformin Therapy

    Not yet reported Shionogi 218 participants Est. completion 2012-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01240785

    Metformin Versus Insulin in Gestational Diabetes

    Not yet reported Turku University Hospital 221 participants Est. completion 2012-12
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT01241448

    A Study of LY2409021 in Patients With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 263 participants Est. completion 2012-03 40 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01241669

    Randomized, Placebo-controlled Study to Evaluate Effects of E5555 on Renal Function Parameters and OCT2 Activity

    Not yet reported Eisai Inc. 104 participants 1 site Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT01243385

    Metformin Hydrochloride as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Prostate Cancer

    Not yet reported Swiss Cancer Institute 44 participants Est. completion 2019-08-09 9 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT01244646

    Hypoglycemia- and Weight-related Quality of Life in Patients With Diabetes Mellitus Type 2 on Sulfonylurea Derivatives.

    AstraZeneca 48 participants Est. completion 2012-08 22 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01245166

    A Phase III Randomized, Double-blind, Parallel-group Study to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg Plus Acarbose 50 mg Tablets) Versus Acarbose Alone in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Lotus Pharmaceutical 220 participants Est. completion 2011-12 1 site Stand-alone
    Type 2 diabetes Other conditions: The Objectives of the Study is to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg, Plus Acarbose 50 mg Tablets) Thrice Daily Versus Acarbose 50 mg Thrice Daily Over 16 Weeks in
    View official trial listing →
  • Completed NCT NCT01249677

    Chronic Reduction of Fasting Glycaemia With Insulin Glargine Improves First and Second Phase Insulin Secretion in Patients With Type 2 Diabetes

    Not yet reported Ruhr University of Bochum 14 participants Est. completion 2010-05 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01257334

    Patients With Type 2 Diabetes Mellitus With Insufficient Glycaemic Control Despite Treatment With Metformin Alone or Metformin in Combination With a Sulfonylurea

    Not yet reported Taipei Medical University WanFang Hospital 1390 participants Est. completion 2012-07 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01258075

    Colesevelam for Children With Type 2 Diabetes

    Not yet reported Daiichi Sankyo 236 participants Est. completion 2020-04-21 24 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01266486

    Effect of Metformin on Breast Cancer Metabolism

    Not yet reported Oxford University Hospitals NHS Trust 41 participants Est. completion 2014-05 3 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01267448

    Outpatient Discharge Therapy With Saxagliptin+MetforminXR vs GlipizideXL for Type 2 Diabetes With Severe Hyperglycemia

    Not yet reported Cook County Health 100 participants Est. completion 2015-07-25 1 site
    Type 2 diabetes Other conditions: Hyperglycemia
    View official trial listing →
  • Completed NCT NCT01269996

    JanUmet Before Insulin Lantus In Eastern Population Evaluation Program (JUBILEE) In Type 2 Diabetic Patients

    Not yet reported Chinese University of Hong Kong 71 participants Est. completion 2015-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01273571

    A Pharmacokinetic and Pharmacodynamic Study of Metformin and Canagliflozin in Healthy Adult Volunteers

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 18 participants Est. completion 2011-02 Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01273584

    Metformin in Obese Non-diabetic Pregnant Women

    Not yet reported, Not yet reported Epsom and St Helier University Hospitals NHS Trust 450 participants Est. completion 2015-09 3 sites
    Other conditions: Pregnancy Complications, Obesity
    View official trial listing →
  • Completed NCT NCT01274130

    Investigatory Study of Metformin's Pharmacokinetics, Pharmacodynamics and Drug Drug Interactions Classifying the Group by MATE1 Genotype in Healthy Volunteers

    Not yet reported Yonsei University 30 participants Est. completion 2011-09 1 site Stand-alone
    Other conditions: Healthy Adult
    View official trial listing →
  • Completed NCT NCT01278160

    Comparison of Biphasic Insulin Aspart 30 Twice Daily With Two Different Initial Dosage Split Regimens in Subjects With Type 2 Diabetes: An Extension to Trial BIASP-3756

    Not yet reported Novo Nordisk A/S 179 participants Est. completion 2011-09 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01278485

    Evaluation of Low Blood Sugar Events in Participants With Diabetes (MK-0431-402)

    Merck Sharp & Dohme LLC 726 participants Est. completion 2012-06
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01279512

    Metformin Versus Acarbose Treatment in Infertile Overweight Women With Polycystic Ovary Syndrome (PCOS)

    Not yet reported Royan Institute 50 participants Est. completion 2008-12 1 site Stand-alone
    Other conditions: PCO
    View official trial listing →
  • Completed NCT NCT01280409

    Metformin Postpartum for GDM RCT for Reduced Weight Retention

    Not yet reported The University of Texas Health Science Center, Houston 114 participants Est. completion 2014-08 2 sites Stand-alone
    Other conditions: Diabetes, Gestational
    View official trial listing →
  • Completed NCT NCT01283308

    A Randomized Trial of Diabetes Prevention Through Lifestyle Change in India

    Not yet reported Emory University 599 participants Est. completion 2013-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01286233

    Study of Biomarkers Associated With Fatigue in Patients With Early-Stage Breast Cancer Treated With Metformin or Placebo on NCIC-CTG-MA.32

    NSABP Foundation Inc 394 participants Est. completion 2016-09 256 sites
    Other conditions: Breast Cancer, Depression, Fatigue, Sleep Disorders
    View official trial listing →
  • Completed NCT NCT01289119

    Efficacy and Safety of Alogliptin in Participants With Type 2 Diabetes

    Not yet reported Takeda 506 participants Est. completion 2011-12 21 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01289990

    Safety and Efficacy of Empagliflozin (BI 10773) and Sitagliptin Versus Placebo Over 76 Weeks in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 2705 participants Est. completion 2013-05 243 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01290575

    Multiple Ascending Dose Study of BMS-820132 in Patients With Type 2 Diabetes

    Not yet reported Bristol-Myers Squibb 67 participants Est. completion 2011-11 5 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01292993

    A Study to Evaluate the Interaction of LX4211 and Metformin in Healthy Subjects

    Not yet reported Lexicon Pharmaceuticals 18 participants 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01294553

    An Open Label, Multi-centre, Non-interventional Post-marketing Surveillance to Monitor the Safety and/or Efficacy of AVANDAMET Between June 2004 and January 2010

    GlaxoSmithKline 717 participants Est. completion 2010-01
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01296412

    Comparison of Two Treatment Regimens (Sitagliptin Versus Liraglutide) on Participants Who Failed to Achieve Good Glucose Control on Metformin Alone (MK-0431-403)

    Not yet reported Merck Sharp & Dohme LLC 653 participants Est. completion 2012-02-29 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01298518

    A Multiple Dose Study Of PF-04620110 In Type 2 Diabetes Patients

    Not yet reported Pfizer 48 participants Est. completion 2011-05 3 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01300637

    Effects of Adjunctive Metformin on Metabolic Profiles in Clozapine-treated Schizophrenic Patients

    Not yet reported Taipei Medical University WanFang Hospital 60 participants Est. completion 2011-07 1 site
    Metabolic syndrome Other conditions: Obesity, Schizophrenia
    View official trial listing →
  • Withdrawn NCT NCT01302002

    The Use of Metformin in Early Breast Cancer Patients Pre-Surgery

    Not yet reported Instituto Nacional de Cancer, Brazil Est. completion 2016-02 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT01302145

    Drug to Drug Interaction Study With ASP1941 and Metformin

    Not yet reported Astellas Pharma Inc 36 participants Est. completion 2009-12-09 5 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01302379

    Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors

    Not yet reported University of California, San Diego 333 participants Est. completion 2016-12 1 site
    Other conditions: Breast Neoplasms
    View official trial listing →
  • Status unknown NCT NCT01303055

    Effects of Alogliptin on Pancreatic Beta Cell Function

    Not yet reported Aichi Gakuin University 80 participants Est. completion 2014-12 4 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01305551

    BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States

    Not yet reported AstraZeneca Est. completion 2011-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01306214

    Safety and Efficacy of BI 10773 as add-on to Insulin Regimen in Patients With Type 2 Diabetes Mellitus

    Not yet reported Boehringer Ingelheim 566 participants Est. completion 2013-04 103 sites
    Type 2 diabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT01307306

    Glucose Control in Severely Burned Patients

    Not yet reported Sunnybrook Health Sciences Centre 45 participants Est. completion 2018-03 1 site Stand-alone
    Other conditions: Burns
    View official trial listing →
  • Completed NCT NCT01310231

    A Trial of Standard Chemotherapy With Metformin (vs Placebo) in Women With Metastatic Breast Cancer

    Not yet reported Ozmosis Research Inc. 40 participants Est. completion 2018-03-26 5 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT01310452

    Study on Liver Fat Content and Visceral Fat Mass in Overweight and Obese Type 2 Diabetes Patients After Treatment With Basal Insulin

    Not yet reported Fudan University 50 participants 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01312467

    Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI

    Not yet reported National Cancer Institute (NCI) 45 participants Est. completion 2014-12 4 sites Stand-alone
    Other conditions: Adenomatous Polyp, Colorectal Cancer, Obesity
    View official trial listing →
  • Terminated NCT NCT01316042

    Metformin for the Treatment of Premature Pubarche in Girls

    Not yet reported Milton S. Hershey Medical Center 4 participants Est. completion 2014-04 3 sites
    Other conditions: Premature Pubarche
    View official trial listing →
  • Completed NCT NCT01318109

    Efficacy and Safety of Alogliptin Used Combination With Metformin in Participants With Type 2 Diabetes in Japan

    Not yet reported, Not yet reported Takeda 288 participants Est. completion 2009-04
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01318135

    Long-term Safety Study of Alogliptin Used in Combination With Sulfonylurea or Metformin in Participants With Type 2 Diabetes in Japan

    Not yet reported, Not yet reported Takeda 576 participants Est. completion 2010-04
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01318564

    Diabetic Treatment Adherence

    M.D. Anderson Cancer Center 28 participants Est. completion 2016-08 2 sites
    Other conditions: Endocrine System Diseases
    View official trial listing →
  • Completed NCT NCT01319994

    Prevention of Metabolic Complications of Glucocorticoid Excess

    Not yet reported, Not yet reported Barts & The London NHS Trust 57 participants Est. completion 2015-01 1 site Stand-alone
    Other conditions: Iatrogenic Cushing Disease
    View official trial listing →
  • Completed NCT NCT01324180

    Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 14 participants Est. completion 2017-07-27 5 sites Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT01329016

    Glyburide and Metformin for Gestational Diabetes Mellitus (GDM)

    Not yet reported, Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 177 participants Est. completion 2015-02-28 4 sites
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01332071

    Avandamet Bioequivalence Study Brazil - Fed Administration

    Not yet reported GlaxoSmithKline 26 participants Est. completion 2009-12-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01332370

    Prescription Patterns, Resource Utilization & Costs - Add-on Therapy With Anti Dipeptidyl Peptidase-IVs vs Rosiglitazone

    GlaxoSmithKline 5391 participants Est. completion 2010-12
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01333852

    Metformin Plus Paclitaxel for Metastatic or Recurrent Head and Neck Cancer

    Not yet reported Lucas Vieira dos Santos 45 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: Head and Neck Neoplasms, Squamous Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT01334125

    Adjunctive Metformin Therapy in Double Diabetes

    Not yet reported University of Massachusetts, Worcester 28 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01336322

    Metformin and Sitagliptin in Women With Previous Gestational Diabetes

    Not yet reported University of Pisa 40 participants Est. completion 2018-12 1 site
    Prediabetes
    View official trial listing →
  • Terminated NCT NCT01336673

    Glucophage XR® Observational Study

    Merck KGaA, Darmstadt, Germany 518 participants Est. completion 2013-06 1 site
    Type 2 diabetes Other conditions: GI Side Effect
    View official trial listing →
  • Completed NCT NCT01336751

    Lantus Versus Humalog Mix as add-on Therapy in Type Diabetes Patients Failing Sulfonylurea and Metformin Combination Treatment

    Not yet reported Sanofi 212 participants Est. completion 2002-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01338870

    Study of Safety and Efficacy of PF-04991532 in Subjects With Type 2 Diabetes

    Not yet reported Pfizer 301 participants Est. completion 2012-03 42 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01339143

    Compare the Effect of DPP-IV Inhibitor or TZD on Glycemic Variability and Oxidative Stress in Patient With 2 Diabetes

    Not yet reported Korea University Anam Hospital 80 participants Est. completion 2013-05 1 site
    Other conditions: Diabetes Mellitus, Oxidative Stress
    View official trial listing →
  • Completed NCT NCT01340300

    Exercise and Metformin in Colorectal and Breast Cancer Survivors

    Not yet reported Dana-Farber Cancer Institute 139 participants Est. completion 2017-12 2 sites
    Other conditions: Colorectal Cancer, Breast Cancer
    View official trial listing →
  • Completed NCT NCT01340664

    An Efficacy, Safety, and Tolerability Study of Canagliflozin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy

    Not yet reported Janssen Research & Development, LLC 279 participants Est. completion 2012-04 61 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01341717

    Effects of Sitagliptin on Type 2 Diabetes Mellitus Patients on Treatment With Metformin and Insulin

    Not yet reported Jothydev's Diabetes and Research Centre 440 participants Est. completion 2014-05 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01341795

    Genetic Variation in the Transporters and Hypoglycemic Agents

    Ajou University School of Medicine 100 participants 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01341886

    Effect of Metformin on Decrement in Levothyroxin Dose Required for Thyroid Stimulating Hormone (TSH) Suppression in Patients With Differentiated Thyroid Cancer

    Not yet reported Mashhad University of Medical Sciences 51 participants Est. completion 2011-04 1 site
    Other conditions: Malignant Neoplasm of Thyroid Stage I, Malignant Neoplasm of Thyroid Stage II
    View official trial listing →
  • Status unknown NCT NCT01342042

    The Safety,Preliminary Pharmacodynamics and Pharmacokinetics Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 36 participants Est. completion 2011-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01342614

    The Effect of Metformin on the Correlation Between Hyperinsulinemia and Hypertension

    Not yet reported China-Japan Friendship Hospital 140 participants Est. completion 2009-08 Stand-alone
    Other conditions: Diabetes Mellitus, Essential Hypertension
    View official trial listing →
  • Status unknown NCT NCT01342744

    Metformin in Postmenopausal Women With Metabolic Syndrome

    Not yet reported Mahidol University 40 participants Est. completion 2012-03 1 site Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT01349387

    Effect of Treatment With Metformin in Type 2 Diabetes Patients on Alternative Genes Splicing

    Not yet reported Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète 25 participants Est. completion 2012-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01351753

    Drug Therapy Induced Weight Loss to Improve Blood Vessel Function in Subjects With Obesity

    Not yet reported University of Iowa 128 participants Est. completion 2014-01-09 1 site Stand-alone
    Metabolic syndrome Other conditions: Obesity
    View official trial listing →
  • Withdrawn NCT NCT01352026

    Evaluation of Metformin Activity in Addition to Conventional Treatment of Grade II or III Pulmonary Arterial Hypertension (PAH)

    Not yet reported Nantes University Hospital 2 sites Stand-alone
    Other conditions: Pulmonary Arterial Hypertension
    View official trial listing →
  • Completed NCT NCT01353391

    Metformin in Women With Type 2 Diabetes in Pregnancy Trial

    Not yet reported Mount Sinai Hospital, Canada 500 participants Est. completion 2019-06-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01356381

    Study to Assess the Effect of 24 Weeks of Treatment With Vildagliptin in Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 43 participants Est. completion 2013-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01357135

    An Observational Study of Type II Diabetics Treated With Dual Therapy With or Without Sitagliptin (Januvia®/Xelevia®, MK-0431-201)

    Merck Sharp & Dohme LLC 3453 participants Est. completion 2013-08-31
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01357148

    A Post Marketing Safety Study of Sitagliptin Phosphate/Metformin Hydrochloride (JANUMET®) (MK-0431A-235)

    Merck Sharp & Dohme LLC 143 participants Est. completion 2010-05
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01357876

    Effect of Metformin on Gut Peptides , Bile Acids and Lipid Profiles in Type 2 Diabetics

    Not yet reported GlaxoSmithKline 8 participants Est. completion 2011-07-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01358994

    Metformin Treatment, Renal Function and Lactic Acidosis

    Skane University Hospital 4500 participants Est. completion 2011-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01364350

    TODAY2 Phase 1 Immediate Post-Intervention Observational Follow-up Study

    National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 550 participants Est. completion 2014-02 16 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01364675

    Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects

    Not yet reported Ramathibodi Hospital 8900 participants Est. completion 2016-12 1 site
    Prediabetes Other conditions: Pre-hypertension
    View official trial listing →
  • Completed NCT NCT01365091

    Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-Brazil

    Not yet reported AstraZeneca 112 participants Est. completion 2011-11 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01366391

    Therapeutic Monitoring of Metformin in Women With Polycystic Ovary Syndrome

    Not yet reported Biocinese 24 participants Est. completion 2011-10 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT01367054

    Adverse Events in Pharmaceutical Bioequivalence Study of Two Formulations of Metformine Hydrochloride 500 mg

    Not yet reported Biocinese 26 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Nutritional and Metabolic Diseases
    View official trial listing →
  • Completed NCT NCT01368081

    Empagliflozin (BI 10773) Comprehensive add-on Study in Japanese Subjects With Type 2 Diabetes Mellitus

    Not yet reported Boehringer Ingelheim 1162 participants Est. completion 2013-04 87 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01370707

    A Study to Evaluate the Efficacy and Safety of CJ-30001 and CJ-30002 in Type 2 Diabetes Mellitus Patients

    Not yet reported HK inno.N Corporation 187 participants Est. completion 2012-07 21 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01376557

    Safety and Efficacy of LX4211 With Metformin in Type 2 Diabetes Patients With Inadequate Glycemic Control on Metformin

    Not yet reported Lexicon Pharmaceuticals 299 participants Est. completion 2012-05 56 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01381900

    A Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Alone or in Combination With a Sulphonylurea

    Not yet reported Janssen Research & Development, LLC 678 participants Est. completion 2012-11 25 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01383356

    Comparison of the Bioavailability of Metformin Between Medium Dose Linagliptin/Metformin Tablets and Medium Dose Glucophage Tablet Given With Linagliptin Tablet

    Not yet reported Boehringer Ingelheim 58 participants Est. completion 2011-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01388361

    Comparison of the Efficacy and Safety of Two Intensification Strategies in Subjects With Type 2 Diabetes Inadequately Controlled on Basal Insulin and Metformin

    Not yet reported Novo Nordisk A/S 413 participants Est. completion 2012-07 124 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT01389778

    Polycystic Ovary Syndrome Genetics and Treatment Response

    Not yet reported Massachusetts General Hospital 200 participants Est. completion 2019-10 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01392677

    Evaluation of Safety and Efficacy of Dapagliflozin in Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control on Background Combination of Metformin and Sulfonylurea

    Not yet reported AstraZeneca 311 participants Est. completion 2013-08 42 sites
    Type 2 diabetes Other conditions: High HbA1c Level, Inadequate Glycaemic Control
    View official trial listing →
  • Completed NCT NCT01394887

    Metformin & Inflammation in Pre-diabetic Children

    Not yet reported, Not yet reported Coordinación de Investigación en Salud, Mexico 52 participants Est. completion 2011-07 1 site
    Other conditions: Glucose Intolerance, Inflammation, Diabetes
    View official trial listing →
  • Completed NCT NCT01396564

    Pioglitazone and Metformin in Diabetic Children

    Not yet reported, Not yet reported Coordinación de Investigación en Salud, Mexico 56 participants Est. completion 2011-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01399645

    Study of Liraglutide Versus Insulin on Liver Fat Fraction in Patients With Type 2 Diabetes

    Not yet reported Centre hospitalier de l'Université de Montréal (CHUM) 35 participants Est. completion 2014-06 1 site Stand-alone
    MASLDMASHType 2 diabetes
    View official trial listing →
  • Completed NCT NCT01400191

    The Inhibitory Effect of Metformin on Gluconeogenesis in Relation to Polymorphisms in Organic Cation Transporter 1

    Not yet reported University of Southern Denmark 37 participants Est. completion 2012-12 1 site
    Other conditions: Pharmacogenetics of Metformin
    View official trial listing →
  • Completed NCT NCT01404676

    The Effect of Vildagliptin Based Treatment Versus Sulfonylurea on Glycemic Variability, Oxidative Stress, GLP-1, and Endothelial Function in Patients With Type 2 Diabetes

    Not yet reported Samsung Medical Center 34 participants Est. completion 2012-05 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01404715

    Drug-drug Interaction Study With Metformin and Imatinib

    Not yet reported University of California, San Francisco 11 participants Est. completion 2013-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01405118

    Effect Of CP-690,550 On The Pharmacokinetics Of Metformin In Healthy Volunteers

    Not yet reported Pfizer 24 participants Est. completion 2011-07 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Withdrawn NCT NCT01408095

    A Study in Patients With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 240 participants Est. completion 2012-09 38 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01409395

    Drug-Drug Interaction Study With Metformin and Nizatidine

    Not yet reported University of California, San Francisco 10 participants Est. completion 2013-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01410604

    Adipokines in Obese Adolescents With Insulin Resistance

    Not yet reported Hospital Regional de Alta Especialidad del Bajio 31 participants Est. completion 2010-03 2 sites Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Status unknown NCT NCT01417897

    Human Insulin Analogs: Evaluation of Inflammatory mRNA Expression of Macrophages and Endothelial Function of Short-acting Insulin - HERMES Pilot Study

    Not yet reported ikfe-CRO GmbH 12 participants Est. completion 2012-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01420692

    The Effects of Insulin Detemir and Gliclazide-MR Treatments on Endothelial Functions in Patients With Type 2 Diabetes

    Not yet reported Ankara University 64 participants Est. completion 2012-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01421459

    A Study in Adults With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 759 participants Est. completion 2012-09 62 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01422746

    Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess

    Not yet reported University of Virginia 20 participants Est. completion 2024-12 1 site Stand-alone
    Other conditions: Obesity, Hyperandrogenemia, Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01422876

    Efficacy and Safety of Empagliflozin (BI 10773) / Linagliptin (BI 1356) Fixed Dose Combination in Treatment naïve and Metformin Treated Type 2 Diabetes Patients

    Not yet reported Boehringer Ingelheim 1405 participants Est. completion 2013-09 211 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01423487

    Efficacy and Safety of Metformin in Preventing Patients With Risperidone From Weight Gain and Amenorrhea

    Not yet reported Central South University Est. completion 2013-08 1 site Stand-alone
    Other conditions: Weight Gain, Amenorrhea
    View official trial listing →
  • Completed NCT NCT01425580

    Liraglutide and Heart Failure in Type 2 Diabetes

    Not yet reported Thomas Nystrom 62 participants Est. completion 2016-08 2 sites Added to GLP-1
    Heart failureType 2 diabetes
    View official trial listing →
  • Completed NCT NCT01426399

    Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of LC15-0444 and Metformin After Oral Administration in Healthy Male Subjects

    Not yet reported LG Life Sciences 30 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT01426737

    The Swiss Glucose Variability Study

    Not yet reported University of Zurich 50 participants Est. completion 2013-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01426802

    Vildagliptin 50 mg Twice Daily in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin

    Not yet reported Novartis Pharmaceuticals 150 participants Est. completion 2011-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01427595

    Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone

    Not yet reported University of Virginia 25 participants Est. completion 2015-01-17 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Hyperandrogenism
    View official trial listing →
  • Completed NCT NCT01427920

    Comparison of Biphasic Insulin Aspart 30 Individually Adjusted by the Subject and the Trial Physician, Both Combined With Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 348 participants Est. completion 2012-07 41 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01429506

    Efficacy of Laparoscopic Sleeve Gastrectomy and Intensive Medical Management in Obese Type 2 Diabetes

    Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2012-08 1 site
    Other conditions: Diabetes Mellitus, Obesity
    View official trial listing →
  • Completed NCT NCT01429818

    Endothelial Disfunction Treatment With Glimepiride/Metformin Combination (Glimetal) in Type 2 Diabetes Patients

    Not yet reported Laboratorios Silanes S.A. de C.V. 16 participants Est. completion 2008-01 1 site Stand-alone
    Other conditions: Endothelial Dysfunction, Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT01430351

    Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy

    Not yet reported M.D. Anderson Cancer Center 144 participants Est. completion 2025-02-02 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Glioblastoma, Supratentorial Glioblastoma
    View official trial listing →
  • Completed NCT NCT01433913

    Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery

    Not yet reported National Cancer Institute (NCI) 20 participants Est. completion 2014-04 3 sites Stand-alone
    Other conditions: Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01434186

    A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination With Metformin IR or Metformin XR in Pediatric Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone

    Not yet reported AstraZeneca 32 participants Est. completion 2016-04 16 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01437800

    BIOAVAILABILITY OF GLI/METXR (4/850 mg)

    Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2011-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01437813

    BIOAVAILABILITY OF Glimepiride/Extended Release Metformin (GLI/METXR): High Fat Diet Study

    Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2011-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT01438190

    Metformin in Step-down Regimen Versus Conventional Low Dose Step-up Protocol in Patients With PCOS Undergoing IVF

    Not yet reported University of Modena and Reggio Emilia 120 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Infertility, PCOS
    View official trial listing →
  • Completed NCT NCT01438723

    The Metformin in Coronary Artery Bypass Graft (CABG) (MetCAB) Trial

    Not yet reported Radboud University Medical Center 100 participants Est. completion 2014-07 1 site Stand-alone
    Cardiovascular disease Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Completed NCT NCT01438814

    Linagliptin in Combination With Metformin in Treatment Naive Patients With Type 2 Diabetes Mellitus and Insufficient Glycaemic Control

    Not yet reported Boehringer Ingelheim 689 participants Est. completion 2013-03 90 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01440127

    Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers

    Not yet reported Tufts Medical Center 9 participants Est. completion 2012-10 1 site Stand-alone
    Other conditions: Colon Cancer
    View official trial listing →
  • Completed NCT NCT01441869

    Study in Healthy Subjects to Measure Amount of Drug in Blood After Dosing With Different Saxagliptin / Metformin Produc

    Not yet reported AstraZeneca 28 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Bioequivalence, Log-transformed AUCss and Cmax,ss Values for Saxagliptin and Metformin
    View official trial listing →
  • Completed NCT NCT01442870

    Evaluation of Clinical Safety of Combining Metformin With Anticancer Chemotherapy

    Not yet reported Tufts Medical Center 105 participants Est. completion 2014-11 1 site Stand-alone
    Other conditions: Cancer
    View official trial listing →
  • Completed NCT NCT01443221

    Pharmacokinetics of Mitiglinide and Metformin in Free Combination and Fixed-dose Combination in Healthy Male Subjects.

    Not yet reported JW Pharmaceutical 24 participants Est. completion 2011-01 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01444248

    Compare the Compliance of Patients Treated With Once-daily (od) or Twice-daily (Bid) Glimepiride and Metformin Fixed Combination Therapy

    Not yet reported Handok Inc. 168 participants Est. completion 2012-05 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01452451

    Safety, Tolerability, Pharmacokinetics,Pharmacodynamics Study of LAPS-Exendin in Subjects of Type 2 Diabetes Mellitus

    Not yet reported Hanmi Pharmaceutical Company Limited 72 participants 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01454622

    A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (50 mg/1,000 mg) With Respect to the Individual Components of Canagliflozin (1 x 100 mg) and Metformin IR Tablets (2 x 1,000 mg) in Healthy Volunteers

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 64 participants Est. completion 2011-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01455870

    A Study to Evaluate ITCA 650 Compared to Sitagliptin as add-on Therapy for the Treatment of Type 2 Diabetes

    Not yet reported Intarcia Therapeutics 535 participants Est. completion 2015-07 54 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01455883

    A Study to Evaluate ITCA 650 Compared to Glimepiride for the Treatment of Type 2 Diabetes

    Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01455909

    A Study to Evaluate ITCA 650 Compared to Sitagliptin for the Treatment of Type 2 Diabetes

    Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01455922

    A Study to Evaluate ITCA 650 Compared to Glimepiride as Add on Therapy for the Treatment of Type 2 Diabetes

    Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01457911

    Evaluation of Fixed Dose Combination of Glimepiride and Metformin in Chinese Type 2 Diabetes Patients Inadequately Controlled With Metformin

    Not yet reported Sanofi 244 participants Est. completion 2013-02 22 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01459094

    Effect of Food on a Fixed Dose Combination Tablet of Canagliflozin and Metformin Immediate Release in Healthy Volunteers

    Not yet reported Janssen Research & Development, LLC 24 participants Est. completion 2011-12
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT01459445

    Metformin+ Drospirenone/ethinylestradiol30µg and Flow-mediated Dilation in Polycystic Ovary Syndrome

    Not yet reported Iuliu Hatieganu University of Medicine and Pharmacy 26 participants Est. completion 2012-01 1 site
    Other conditions: Polycystic Ovary Syndrome, Endothelial Dysfunction
    View official trial listing →
  • Completed NCT NCT01459809

    Efficacy and Safety Comparison of Metformin/Glimepiride Combination Versus Each Compound Alone in New Diagnosed Type 2 Diabetes Patients

    Not yet reported Sanofi 538 participants Est. completion 2014-01 55 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01460797

    Metabolic Effects of a Caloric Restriction High/Low Glycemic Index Diet Plus Metformin in Overweight/Obese Subjects

    Not yet reported Caio Eduardo Gonçalves Reis 41 participants Est. completion 2006-10 1 site
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT01462266

    Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260)

    Not yet reported Merck Sharp & Dohme LLC 660 participants Est. completion 2013-06-07 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01463228

    A Study to Assess the Bioequivalence of Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers

    Not yet reported Janssen Research & Development, LLC 83 participants Est. completion 2012-01 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01463774

    A Study to Assess the Bioequivalence of 2 Fixed Dose Combination Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers

    Not yet reported Janssen Research & Development, LLC 74 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01464437

    AMG 151 Amgen Protocol Number 20100761

    Not yet reported Amgen 236 participants Est. completion 2012-12 77 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01465113

    Vitamin D Supplementation on 15-Prostaglandin Dehydrogenase Expression in Barrett's Esophagus

    Not yet reported Case Comprehensive Cancer Center 26 participants Est. completion 2016-02 3 sites Stand-alone
    Other conditions: Short Segment Barrett's Esophagus, Long Segment Barrett's Esophagus
    View official trial listing →
  • Completed NCT NCT01465152

    Comparison of Metformin, Repaglinide or the Combination of Both in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 182 participants Est. completion 2004-10-21 18 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT01471275

    Chinese Medicine Treatment of Obesity With Type 2 Diabetes, Dyslipidemia

    Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 450 participants Est. completion 2013-12 8 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01471808

    Effects of Different Early Intensive Therapies on Long-term β-cell Function

    Not yet reported Sun Yat-sen University 264 participants Est. completion 2018-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01472432

    DPP IV Inhibition Facilitates Healing of Chronic Foot Ulcers in Type 2 Diabetes

    Not yet reported University of Campania Luigi Vanvitelli 106 participants Est. completion 2016-01 1 site Stand-alone
    Other conditions: Chronic Foot Ulcers
    View official trial listing →
  • Completed NCT NCT01474018

    QR-Bromocriptine as an Adjunct to Insulin and Metformin in the Treatment of Type 2 Diabetes

    Not yet reported University of Texas Southwestern Medical Center 15 participants Est. completion 2012-06 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01474967

    Effect of Dosage of Metformin on Menstruation and Lipid Profile in Women With Polycystic Ovary Syndrome

    Not yet reported Hormozgan University of Medical Sciences 50 participants Est. completion 2011-02 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01475461

    Phase 2 Study To Evaluate Safety And Efficacy Of Investigational Drug - PF04937319 In Patients With Type 2 Diabetes

    Not yet reported Pfizer 345 participants Est. completion 2013-01 63 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01476475

    Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Combination Versus Insulin Glargine Alone on Top of Metformin in Type 2 Diabetic Patients

    Not yet reported Sanofi 323 participants Est. completion 2012-12 70 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01477060

    Modulation of Response to Hormonal Therapy With Lapatinib and/or Metformin in Patients With Metastatic Breast Cancer

    Not yet reported Fondazione Michelangelo 32 participants Est. completion 2013-12 11 sites
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Terminated NCT NCT01477853

    A Study of the Co-administration of Sitagliptin and Atorvastatin in Inadequately Controlled Type 2 Diabetes Mellitus (MK-0431E-211)

    Not yet reported Merck Sharp & Dohme LLC 166 participants Est. completion 2012-12-04 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01478308

    Metformin With Standard Taxotere and Prednisone in the Treatment of Castration Resistant Prostate Cancer

    Not yet reported New Mexico Cancer Research Alliance Est. completion 2011-10
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT01481116

    Efficacy and Safety of TAK-875 Compared to Glimepiride When Used With Metformin in Participants With Type 2 Diabetes

    Not yet reported Takeda 2454 participants Est. completion 2014-04 226 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01482286

    Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS

    Not yet reported Pennington Biomedical Research Center 32 participants Est. completion 2016-12 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01483560

    REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL)

    Not yet reported University of Glasgow 493 participants Est. completion 2017-04-18 24 sites Stand-alone
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT01483781

    A Study of the Effects of Canagliflozin on Plasma Volume in Patients With Type 2 Diabetes Mellitus

    Not yet reported Janssen Research & Development, LLC 36 participants Est. completion 2012-08 1 site
    Type 2 diabetes Other conditions: Plasma Volume
    View official trial listing →
  • Completed NCT NCT01485614

    Study to Assess Safety & Efficacy of Sitagliptin as Initial Oral Therapy for Treatment of Type 2 Diabetes Mellitus in Pediatric Participants. (MK-0431-083)

    Not yet reported Merck Sharp & Dohme LLC 200 participants Est. completion 2019-10-09 Stand-alone
    Type 2 diabetes Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT01486966

    Comparing Efficacy and Safety of Insulin Detemir Plus Insulin Aspart and NPH Insulin Plus Human Soluble Insulin With or Without Metformin in Chinese Patients With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 58 participants Est. completion 2012-06 6 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01487993

    Metformin in Obese Children and Adolescents

    Not yet reported St. Antonius Hospital 62 participants Est. completion 2017-02-28 2 sites
    Other conditions: Obesity, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT01488552

    Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancer

    Not yet reported, Not yet reported Pancreatic Cancer Research Team 60 participants Est. completion 2016-08 5 sites Stand-alone
    Other conditions: Stage IV Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT01489644

    Single Dose Pharmacokinetics of Repaglinide, Metformin and Combination Tablet in Healthy Volunteers

    Not yet reported Novo Nordisk A/S 62 participants Est. completion 2006-07 2 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01490658

    Single Dose Pharmacokinetics of Repaglinide, Metformin and Combination Tablet in Fed Healthy Volunteers

    Not yet reported Novo Nordisk A/S 93 participants Est. completion 2006-08 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01490918

    Study to Evaluate the Efficacy of Acarbose,Metformin,Sitagliptin Combination Treatment in DM Patients

    Not yet reported The Catholic University of Korea 165 participants Est. completion 2014-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01496430

    Efficacy and Safety of Azilsartan Medoxomil Used in Combination With Metformin in Participants With Hypertension and Diabetes

    Not yet reported Takeda 105 participants Est. completion 2013-05 68 sites
    Other conditions: Hypertension, Diabetes
    View official trial listing →
  • Completed NCT NCT01497522

    Efficacy and Safety of Vildagliptin as add-on Therapy to Metformin in Patients With Type 2 Diabetes

    Not yet reported Novartis Pharmaceuticals 183 participants Est. completion 2013-02 20 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01505426

    A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Metformin in Asian Diabetes Patients

    Not yet reported Astellas Pharma Inc 171 participants Est. completion 2013-01-14 12 sites Stand-alone
    Other conditions: Type II Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01508182

    A Study of Canagliflozin and Metformin Immediate Release (150 mg/500 mg) FDC Tablets in Healthy Volunteers

    Not yet reported Janssen Research & Development, LLC 64 participants Est. completion 2012-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01508195

    A Study of Canagliflozin and Metformin Immediate Release (50 mg/500 mg) FDC Tablets in Healthy Volunteers

    Not yet reported Janssen Research & Development, LLC 64 participants Est. completion 2012-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01509001

    Study of Metabolic and Haemodynamic Effects of Metformin and Glimepiride in Patients With Type 2 Diabetes Mellitus

    Not yet reported University of Sao Paulo 20 participants Est. completion 2012-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01510522

    Evaluate Adherence to Treatment With Glucophage Sachets Versus Tablets in Diabetes Type 2 Patients Previously Treated With Metformin Tablets

    Not yet reported Merck KGaA, Darmstadt, Germany Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01511172

    Effect of Liraglutide as add-on to Metformin Compared to Either Liraglutide or Metformin Alone, or to a Combination of Metformin and a SU (Sulphonylurea) Agent in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 145 participants Est. completion 2002-12 41 sites Mixed
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01511198

    Efficacy and Safety of Metformin and Liraglutide in Obese Subjects With Type 2 Diabetes Previously Treated With an Oral Hypoglycemic Agent

    Not yet reported Novo Nordisk A/S 223 participants Est. completion 2001-10 39 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01512979

    Linagliptin and Metformin Versus Linagliptin in Newly Diagnosed, Untreated Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 316 participants Est. completion 2013-04 82 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01513590

    A Trial Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart and BIAsp 30 in Insulin naïve Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 394 participants Est. completion 2012-11-19 49 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT01514149

    Dose-Ranging Study to Evaluate Efficacy and Safety of Weekly CJC-1134-PC in Patients With T2DM on Metformin Monotherapy

    Not yet reported ConjuChem 73 participants Est. completion 2013-03 22 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01517373

    Study To Understand Efficacy And Safety Of Investigational Agent (PF-04937319) Compared To Approved Agent (Glimepiride) In Patients With Diabetes On Metformin

    Not yet reported Pfizer 304 participants Est. completion 2013-01 53 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01517412

    Comparison of Lixisenatide Injected Prior to the Main Meal of the Day Versus Prior to Breakfast in Type 2 Diabetic Patients on Metformin

    Not yet reported Sanofi 451 participants Est. completion 2013-05 82 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01518101

    Vildagliptin Versus Liraglutide - Patient Preference After Receiving Both Medications

    Not yet reported Novartis Pharmaceuticals 62 participants Est. completion 2012-10 8 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01518712

    A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (150 mg/850 mg) With Respect to the Individual Components of Canagliflozin (1 x 300 mg) and Metformin IR Tablets (2 x 850 mg) in Healthy Volunteers

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 64 participants Est. completion 2011-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01519674

    Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin

    Not yet reported Novo Nordisk A/S 582 participants Est. completion 2013-10 69 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT01523639

    A Randomized, Placebo-controlled, Double-blind Phase II Study Evaluating if Glucophage Can Avoid Liver Injury Due to Chemotherapy Associated Steatosis

    Not yet reported Austrian Breast & Colorectal Cancer Study Group 8 participants Est. completion 2014-04 7 sites
    Other conditions: Colorectal Cancer, Steatohepatitis
    View official trial listing →
  • Completed NCT NCT01524705

    FLuctuATion Reduction With inSULin and Glp-1 Added togetheR (FLAT-SUGAR)

    Not yet reported University of Washington 102 participants Est. completion 2014-07 12 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01525225

    Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DM

    Not yet reported AstraZeneca 4 participants Est. completion 2013-06 7 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01525823

    Assessment of Blood Glucose Changes in Healthy Volunteers After BMS-754807 Alone or BMS-754807 With Metformin

    Not yet reported Bristol-Myers Squibb 26 participants Est. completion 2012-04 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT01526317

    A Phase 1 Clinical Trial to Investigate Pharmacokinetics and Drug Interaction of Crestor and Glucodown OR SR in Healthy Volunteers

    Not yet reported Yuhan Corporation 36 participants Est. completion 2012-05 1 site Stand-alone
    Other conditions: Pharmacokinetics and Drug Interaction of Crestor and Glucodown SR
    View official trial listing →
  • Completed NCT NCT01526616

    Spironolactone Plus Metformin in Polycystic Ovary Syndrome

    Not yet reported University Magna Graecia 56 participants Est. completion 2011-07
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01528046

    Metformin in Children With Relapsed or Refractory Solid Tumors

    Not yet reported H. Lee Moffitt Cancer Center and Research Institute 26 participants Est. completion 2020-02-03 14 sites Stand-alone
    Other conditions: Solid Tumors, Primary Brain Tumors
    View official trial listing →
  • Completed NCT NCT01528254

    VERIFY:A Study to Compare Combination Regimen With Vildagliptin & Metformin Versus Metformin in Treatment-naïve Patients With Type 2 Diabetes Mellitus

    Not yet reported Novartis Pharmaceuticals 2004 participants Est. completion 2019-04-04 227 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01529177

    Metformin for the Treatment of Unexplained Oligozspermia

    Not yet reported The Egyptian IVF-ET Center 600 participants Est. completion 2017-02 1 site Stand-alone
    Other conditions: Infertility
    View official trial listing →
  • Completed NCT NCT01529541

    Efficacy and Safety of CWP-0403 Compared to Sitagliptin in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin Alone

    Not yet reported JW Pharmaceutical 200 participants Est. completion 2013-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01529593

    Temsirolimus in Combination With Metformin in Patients With Advanced Cancers

    Not yet reported M.D. Anderson Cancer Center 34 participants Est. completion 2025-03-14 1 site Stand-alone
    Other conditions: Advanced Cancers
    View official trial listing →
  • Completed NCT NCT01535677

    To Compare the Similarity of a Combination Dapagliflozin/Metformin Tablet With the Two Drugs Administered Separately

    Not yet reported AstraZeneca 71 participants Est. completion 2013-07 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01540487

    Pharmacokinetics of Fixed Dose Combination (FDC) Tablets of Linagliptin /Metformin

    Not yet reported Boehringer Ingelheim 48 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01541215

    Efficacy and Safety of Liraglutide in Combination With Metformin Compared to Metformin Alone, in Children and Adolescents With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 135 participants Est. completion 2020-05-20 185 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01541956

    Efficacy of VIldagliptin aS an Add-on Therapy to Metformin Compared to Metformin Up-TitratION in Chinese Patients With Type 2 Diabetes.(VISION)

    Not yet reported Novartis Pharmaceuticals 3091 participants Est. completion 2013-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01544751

    Nonalcoholic Fatty Liver Disease (NAFLD) Pharmacological Treatment: Metformin Versus Atorvastatin

    Not yet reported Prof Antonino Belfiore 150 participants Est. completion 2015-06 1 site
    MASLD
    View official trial listing →
  • Completed NCT NCT01545388

    Metformin Add-on Regimen Comparison Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431A-136)

    Not yet reported Merck Sharp & Dohme LLC 337 participants Est. completion 2013-03-12 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01546558

    Single Cohort, 2-Period Study to Assess Pharmacokinetics of Metformin Alone and in Combination With Ranolazine 500 mg

    Not yet reported Gilead Sciences 25 participants Est. completion 2012-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01546597

    Single Cohort 4-period Study to Assess Pharmacokinetics of Metformin Alone and in Combination With Ranolazine

    Not yet reported Gilead Sciences 24 participants Est. completion 2012-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01547104

    Effect of Linagliptin in Comparison With Glimepiride as Add on to Metformin on Postprandial Beta Cell Function, Postprandial Metabolism and Oxidative Stress in Patients With Type 2 Diabetes Mellitus

    Not yet reported Marcus Borchert 40 participants Est. completion 2012-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01549964

    Comparison of Fasiglifam (TAK-875) to Placebo and Sitagliptin in Combination With Metformin in Participants With Type 2 Diabetes

    Not yet reported Takeda 916 participants Est. completion 2014-03 160 sites Stand-alone
    Other conditions: Glycemic Control
    View official trial listing →
  • Withdrawn NCT NCT01550900

    Prospective Trial of Metformin - Chemoprevention Role

    Not yet reported M.D. Anderson Cancer Center
    Other conditions: Colorectum
    View official trial listing →
  • Completed NCT NCT01551615

    A Phase I Study to Assess the Pharmacokinetics of Metformin When Administered Alone and in Combination With Vandetanib

    Not yet reported Sanofi 14 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01555164

    A Phase 3 Study of Ranolazine in Subjects With Type 2 Diabetes Who Are Inadequately Controlled on Metformin Alone

    Not yet reported Gilead Sciences 442 participants Est. completion 2013-10 146 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01557504

    A Study to Assess the Pharmacokinetics and the Ability for Pediatric Participants With Type 2 Diabetes to Swallow MK-0431A XR Tablets (MK-0431A-296)

    Not yet reported Merck Sharp & Dohme LLC 25 participants Est. completion 2014-04-29 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01560481

    Clinical Trial to Evaluate Safety and pK Profile of Metformin Glycinate in Healthy Volunteers

    Not yet reported Laboratorios Silanes S.A. de C.V. 49 participants Est. completion 2013-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Withdrawn NCT NCT01561482

    Study of Metformin With Simvastatin for Men With Prostate Carcinoma

    Not yet reported Nicholas Mitsiades Est. completion 2014-07 3 sites Stand-alone
    Other conditions: Prostate Carcinoma
    View official trial listing →
  • Completed NCT NCT01561976

    Evaluation of Food Effect on the Pharmacokinetics of Sustained Release Metformin in Healthy Indian Volunteers

    Not yet reported GlaxoSmithKline 30 participants Est. completion 2012-02-21
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01563120

    A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus

    Not yet reported HaEmek Medical Center, Israel 108 participants Est. completion 2014-12 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT01565096

    Effect of Adding Vildagliptin on Beta Cell Function and Cardiovascular Risk Markers in Patients With Moderate Metabolic Control During Metformin Monotherapy

    Not yet reported ikfe-CRO GmbH 44 participants 1 site Stand-alone
    Other conditions: Diabetes Mellitus Type II
    View official trial listing →
  • Status unknown NCT NCT01566799

    Metformin Plus Neoadjuvant Chemotherapy in Breast Cancer

    Not yet reported Instituto Nacional de Cancerologia de Mexico 60 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: Locally Advanced Malignant Neoplasm
    View official trial listing →
  • Completed NCT NCT01573377

    Efficacy of Metformin and Diane-35 on PCOS Patients,a Randomized, Controlled, Prospective Clinical Trial

    Not yet reported Chongqing Medical University 40 participants Est. completion 2013-02 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT01573949

    A Pilot Study: Metformin Therapy in Heart Failure Patients With Early Diabetes or at High Risk of Developing Diabetes (Pre-Diabetes)

    Not yet reported University of California, Los Angeles 7 participants Est. completion 2012-12 1 site Stand-alone
    Heart failure Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01576328

    Safety Study of Mesenchymal Precursor Cells in Type 2 Diabetes

    Not yet reported, Not yet reported Mesoblast, Ltd. 61 participants Est. completion 2015-10 18 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01578551

    Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 25 participants Est. completion 2017-01 2 sites Stand-alone
    Other conditions: Carcinoma, Non-Small-Cell Lung, Lung Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT01579812

    Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic Patients

    Not yet reported University of Michigan Rogel Cancer Center 90 participants Est. completion 2017-07 1 site Stand-alone
    Other conditions: Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
    View official trial listing →
  • Completed NCT NCT01581814

    Effects of Drospirenone-ethinylestradiol and/or Metformin on Cardiovascular Risk in Hyperinsulinemic Women With Polycystic Ovary Syndrome

    Not yet reported Catholic University of the Sacred Heart 99 participants Est. completion 2012-03 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01581931

    Bioequivalence of Metformin Under Fed Conditions After Administration of Linagliptin / Metformin Fixed Dose Combination Tablet and Single Tablets

    Not yet reported Boehringer Ingelheim 32 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01582230

    Efficacy and Safety of Vildagliptin 50mg Bid as an add-on Therapy to Insulin With or Without Metformin, in Patients With Type 2 Diabetes Mellitus

    Not yet reported Novartis Pharmaceuticals 293 participants Est. completion 2013-05 21 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01582243

    Safety and Efficacy of Vildagliptin Plus Metformin (SPC) Treatment in Type 2 Diabetes Mellitus Patients

    Not yet reported Novartis Pharmaceuticals 40 participants Est. completion 2015-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01584232

    A Study of Dulaglutide in Japanese Participants With Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 361 participants Est. completion 2013-07 15 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01587378

    Metformin to Prevent Late Miscarriage and Preterm Delivery in Women With Polycystic Ovary Syndrome

    Not yet reported Norwegian University of Science and Technology 489 participants Est. completion 2017-10-31 13 sites Stand-alone
    Other conditions: Pregnancy, Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01589367

    Neoadjuvant Letrozole Plus Metformin vs Letrozole Plus Placebo for ER-positive Postmenopausal Breast Cancer

    Not yet reported Seoul National University Hospital 208 participants Est. completion 2018-08 1 site Stand-alone
    Other conditions: Hormone Receptor Positive Malignant Neoplasm of Breast
    View official trial listing →
  • Completed NCT NCT01589445

    Efficacy Study of Pioglitazone and Metformin and Association Between Pioglitazone Response and Peroxisome Proliferator-activated Receptor Gamma Gene Variants in Bangladeshi Type 2 Diabetes Mellitus Subjects

    Not yet reported University of Dhaka 77 participants Est. completion 2010-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01589653

    Comparing Patient-adjusted Versus Physician-adjusted Titration of BIAsp 30 Combined With Metformin in Type 2 Diabetes Patients

    Not yet reported Novo Nordisk A/S 155 participants Est. completion 2015-07-09 15 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01590771

    A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Sulfonylurea With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-253)

    Not yet reported Merck Sharp & Dohme LLC 498 participants Est. completion 2014-06-24 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01593137

    A Long-term Trial to Compare the Effects of Liraglutide and Sulphonylurea (Glimepiride) Both in Combination With Metformin on Clinical, Endothelial and Image Markers of Cardiovascular Risk in Patients With Type 2 Diabetes

    Not yet reported Fundación Fernández-Cruz Est. completion 2014-12 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01593371

    Comparison of Metformin and Pioglitazone Effects on Adipokines Concentrations in Newly Diagnosed Type 2 Diabetes Patients

    Not yet reported Tehran University of Medical Sciences 98 participants Est. completion 2012-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01594697

    Metformin in Pregnancy in Women With Polycystic Ovary Syndrome

    Not yet reported Catholic University of the Sacred Heart 60 participants 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01595789

    The Effect of Liraglutide on the Treatment of Coronary Artery Disease and Type 2 Diabetes

    Not yet reported Haugaard, Steen Bendix, M.D., DMSc 41 participants Est. completion 2015-07 1 site
    Cardiovascular diseaseType 2 diabetes
    View official trial listing →
  • Completed NCT NCT01595880

    BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 500mg in Comparison to Each Component Administered Alone

    Not yet reported LG Life Sciences 29 participants Est. completion 2015-01 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01596504

    Pharmacodynamic Effects of Lixisenatide Compared to Liraglutide in Patients With Type 2 Diabetes Not Adequately Controlled With Insulin Glargine With or Without Metformin

    Not yet reported Sanofi 142 participants Est. completion 2013-07 8 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01602003

    Phase III Trial to Evaluate the Efficacy and Safety of LC15-0444 Compared With Sitagliptin Added to Ongoing Metformin Therapy in Patients With Type 2 Diabetes

    Not yet reported LG Life Sciences 425 participants Est. completion 2012-05 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01604213

    Effects of Vildagliptin/Metformin Combination on Markers of Atherosclerosis, Thrombosis, and Inflammation in Diabetics With Coronary Artery Disease

    Not yet reported Sheba Medical Center 60 participants Est. completion 2016-04 1 site Stand-alone
    Type 2 diabetes Other conditions: Ischemic Heart Disease
    View official trial listing →
  • Completed NCT NCT01606007

    Safety and Efficacy of Combination Saxagliptin & Dapagliflozin Added to Metformin to Treat Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 1282 participants Est. completion 2014-01 139 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01610401

    The Metformin-FMD Trial

    Not yet reported Radboud University Medical Center 26 participants Est. completion 2013-01 1 site
    Other conditions: Ischemia Reperfusion Injury, Endothelial Function
    View official trial listing →
  • Completed NCT NCT01612741

    Diabetes Treatment With Glucobay in Combination With Metformin

    Bayer 19509 participants Est. completion 2009-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01612858

    Metabolic Abnormalities in HIV-infected Persons

    Not yet reported Tufts Medical Center 20 participants Est. completion 2014-11 1 site Stand-alone
    Other conditions: Lipodystrophy, HIV Infection
    View official trial listing →
  • Completed NCT NCT01613755

    Metformin-Dipyridamole Interaction Trial

    Not yet reported Radboud University Medical Center 18 participants Est. completion 2012-07 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01617434

    The Effect of Liraglutide Versus Placebo When Added to Basal Insulin Analogues With or Without Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 451 participants Est. completion 2013-10 86 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01618162

    The Efficacy of Insulin Degludec/Liraglutide as add-on Therapy in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on Sulphonylurea With or Without Metformin Therapy

    Not yet reported Novo Nordisk A/S 435 participants Est. completion 2013-10-23 87 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01619059

    Safety and Efficacy of Saxagliptin in Triple Therapy to Treat Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 315 participants Est. completion 2015-01 83 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01620593

    Castration Compared to Castration Plus Metformin as First Line Treatment for Patients With Advanced Prostate Cancer

    Not yet reported The University of Texas Health Science Center at San Antonio 41 participants Est. completion 2016-09 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01622257

    Cavitation Ultrasound in Treatment of Patients With PCOS

    Not yet reported Ain Shams University 198 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT01624116

    Comparison of Hypoglycaemic Regimens During Ramadan Fasting in Type 2 Diabetes

    Not yet reported Services Hospital, Lahore 161 participants Est. completion 2011-09 1 site
    Other conditions: Diabetes, Type 2
    View official trial listing →
  • Completed NCT NCT01624259

    A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes

    Not yet reported Eli Lilly and Company 599 participants Est. completion 2013-11 57 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01627067

    Exemestane-RAD001-Metformin

    Not yet reported M.D. Anderson Cancer Center 23 participants Est. completion 2019-02-01 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT01632020

    Effect of Metformin on Biomarkers of Colorectal Tumor Cell Growth

    Not yet reported University of Arkansas 7 participants Est. completion 2015-01 2 sites
    Other conditions: Colorectal Neoplasms
    View official trial listing →
  • Completed NCT NCT01632163

    Assessment of the Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Insufficiently Controlled With Basal Insulin +/- Metformin

    Not yet reported Sanofi 447 participants Est. completion 2015-05 51 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01638988

    Clomifene Citrate Versus Metformin in First-line Treatment of Infertility in Patients With Polycystic Ovary Syndrome and a Resistance to Insulin

    Not yet reported Clinique Ovo Est. completion 2015-12 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT01646320

    Safety and Efficacy of Dapagliflozin in Triple Therapy to Treat Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 320 participants Est. completion 2015-02 66 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01648582

    A Study Comparing the Effects and Safety of Dulaglutide With Insulin Glargine in Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 774 participants Est. completion 2014-12 30 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01649297

    A 16 Weeks Study on Efficacy and Safety of Two Doses of Empagliflozin (BI 10773) (Once Daily Versus Twice Daily) in Patients With Type 2 Diabetes Mellitus and Preexisting Metformin Therapy

    Not yet reported Boehringer Ingelheim 983 participants Est. completion 2013-12 139 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01650181

    Effects of Siliphos-Selenium-Methionine-Alpha Lipoic Acid in Patients With Fatty Liver and Non-alcoholic Steatohepatitis

    Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 50 participants Est. completion 2014-06 1 site
    Other conditions: Liver Disease
    View official trial listing →
  • Completed NCT NCT01650506

    Study of Erlotinib and Metformin in Triple Negative Breast Cancer

    Not yet reported Columbia University 8 participants Est. completion 2016-06 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT01654640

    The Effect of Metformin on Obesity and Metabolic Disturbance in Patients Taking Clozapine

    Not yet reported Seoul National University Hospital 15 participants Est. completion 2015-04 1 site Stand-alone
    Other conditions: Schizophrenia
    View official trial listing →
  • Completed NCT NCT01656057

    The Impact of Gall Bladder Emptying and Bile Acids on the Human GLP-1-secretion

    Not yet reported Filip Krag Knop 10 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: To Assess the Impact of Bile Acids on Human Glukagon-like-peptide-1 Secretion
    View official trial listing →
  • Completed NCT NCT01658501

    Phase 2b Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM

    Not yet reported PhaseBio Pharmaceuticals Inc. 593 participants Est. completion 2013-07 93 sites Mixed
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01658514

    Assessing the Behavior of Met DR in Subjects With Kidney Dysfunction

    Not yet reported Elcelyx Therapeutics, Inc. 39 participants Est. completion 2014-06 Stand-alone
    Other conditions: Renal Insufficiency
    View official trial listing →
  • Completed NCT NCT01662674

    BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone

    Not yet reported LG Life Sciences 27 participants Est. completion 2013-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01664247

    The Effect of Insulin Degludec in Combination With Liraglutide and Metformin in Subjects With Type 2 Diabetes Qualifying for Treatment Intensification

    Not yet reported Novo Nordisk A/S 346 participants Est. completion 2013-12-31 132 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01664624

    Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 Diabetes

    Not yet reported AstraZeneca 40 participants Est. completion 2012-11 2 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01664845

    Effects of Metformin, Pegylated Interferon Alpha and Ribavirin for Chronic Hepatitis C With Insulin Resistance

    Not yet reported, Not yet reported Kaohsiung Veterans General Hospital. 120 participants Est. completion 2014-08 1 site
    Other conditions: Chronic Hepatitis c, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT01665352

    A Study to Evaluate Safety and Efficacy of TTP054 for 12 Weeks in Subjects With Type 2 Diabetes

    Not yet reported vTv Therapeutics 186 participants Est. completion 2013-05 19 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01666171

    Studying Changes in Breast Density in Patients With Early-Stage Breast Cancer Treated With Metformin Hydrochloride or Placebo on CAN-NCIC-MA.32

    Cancer and Leukemia Group B 458 participants
    Other conditions: Breast Cancer
    View official trial listing →
  • Terminated NCT NCT01666665

    Mechanisms of Improved Wound Healing and Protein Synthesis of Insulin and Metformin

    Not yet reported, Not yet reported The University of Texas Medical Branch, Galveston 36 participants Est. completion 2019-04-23 1 site
    Other conditions: Insulin Resistance, Hypermetabolism, Hyperglycemia
    View official trial listing →
  • Completed NCT NCT01666730

    Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer

    Not yet reported Case Comprehensive Cancer Center 50 participants Est. completion 2018-08-01 2 sites Stand-alone
    Other conditions: Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage IV Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT01672788

    Demonstration of Bioequivalence of Empagliflozin and Metformin Given in One Tablet Compared to the Intake of Single Tablets

    Not yet reported Boehringer Ingelheim 36 participants Est. completion 2012-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT01674348

    A Clinical Trial to Study the Efficacy, Safety, Tolerability and Pharmacokinetics of P2202 in Patients of Type 2 Diabetes

    Not yet reported Piramal Enterprises Limited 48 participants Est. completion 2013-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01675310

    Medical Nutrition Therapy Plus Transgestational Metformin For Preventing Gestational Diabetes In High Risk Mexican Women

    Not yet reported Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes 90 participants Est. completion 2015-03 1 site Stand-alone
    Other conditions: Pregestational Obesity (BMI > 27kg/m2), History of Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01677260

    Bioequivalence Study of Two Formulations of 500 mg Metformin Extended Release Tablet

    Not yet reported Dexa Medica Group 38 participants Est. completion 2010-01 1 site Stand-alone
    Other conditions: Metformin XR BE Study in Healthy Volunteers With Single and Multiple Dose
    View official trial listing →
  • Completed NCT NCT01677299

    Assessing the PK and Effect on Glucose and GI Hormone Concentrations of Metformin Delayed-Release in Subjects With T2DM

    Not yet reported, Not yet reported Elcelyx Therapeutics, Inc. 24 participants Est. completion 2012-09 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01677897

    Impact of the Addition of Metformin to Abiraterone in Metastatic Prostate Cancer Patients

    Not yet reported Kantonsspital Graubünden 25 participants Est. completion 2018-06 1 site Stand-alone
    Other conditions: Metastatic Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01677923

    Obesity in Children and Adolescents: Associated Risks and Early Intervention

    Not yet reported Lithuanian University of Health Sciences 182 participants Est. completion 2015-12 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Terminated NCT NCT01678820

    A Study of the Efficacy and Safety of MK-0431D (a Fixed-dose Combination of Sitagliptin and Simvastatin) for the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-266)

    Not yet reported Merck Sharp & Dohme LLC 299 participants Est. completion 2013-11-01 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01679574

    Letrozole or Combined Clomiphene Citrate Metformin as a First Line Treatment in Women With Polycystic Ovarian Syndrome

    Not yet reported Assiut University 200 participants Est. completion 2012-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01681693

    Effect of Genetic Variants in MATE1 and OCT3 on the Pharmacodynamics of Metformin in African Americans

    Not yet reported University of California, San Francisco 33 participants Est. completion 2013-07 1 site Stand-alone
    Type 2 diabetes Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01682759

    A Study of the Safety and Efficacy of Omarigliptin (MK-3102) Compared With Glimepiride in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-016)

    Not yet reported Merck Sharp & Dohme LLC 751 participants Est. completion 2015-01-26 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01685762

    Metformin for the Treatment of Endometrial Hyperplasia

    Not yet reported UNC Lineberger Comprehensive Cancer Center 18 participants Est. completion 2015-12-01 3 sites Stand-alone
    Other conditions: Endometrial Hyperplasia, Endometrial Hyperplasia Without Atypia
    View official trial listing →
  • Active, not recruiting NCT NCT01686126

    Improving the Treatment for Women With Early Stage Cancer of the Uterus

    Not yet reported Queensland Centre for Gynaecological Cancer 165 participants Est. completion 2026-12 17 sites Stand-alone
    Other conditions: Complex Endometrial Hyperplasia With Atypia, Grade 1 Endometrial Endometrioid Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT01690091

    Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes

    Not yet reported, Not yet reported Institute for Clinical and Experimental Medicine 40 participants Est. completion 2016-12 1 site Stand-alone
    Heart failure Other conditions: Insulin Resistance
    View official trial listing →
  • Completed NCT NCT01691846

    A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Alone

    Not yet reported Hoffmann-La Roche 200 participants Est. completion 2013-09 31 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01691989

    A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Sulfonylurea Alone or Sulfonylurea Plus Metformin Therapy

    Not yet reported Hoffmann-La Roche 197 participants Est. completion 2013-09 28 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01693289

    Study to Compare Between Combimed Metformin-letrozole and Ovarian Drilling in Pcos With Bilateral Ovarian Drilling in Clomiphene-resistant Infertile Women With Polycystic Ovarian Syndrome

    Not yet reported Zagazig University 146 participants Est. completion 2012-07 1 site Stand-alone
    Other conditions: Focus of Study
    View official trial listing →
  • Completed NCT NCT01697566

    An Endometrial Cancer Chemoprevention Study of Metformin

    Not yet reported M.D. Anderson Cancer Center 29 participants Est. completion 2024-05-30 1 site Stand-alone
    Other conditions: Gynecology
    View official trial listing →
  • Completed NCT NCT01697592

    Omarigliptin (MK-3102) Clinical Trial - Add-on to Oral Antihyperglycemic Agent Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-3102-015)

    Not yet reported Merck Sharp & Dohme LLC 585 participants Est. completion 2014-05-08 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01699932

    Efficacy and Safety of the Fixed Dose Combination of Glimepiride+Metformin in Type 2 Diabetic Patients Inadequately Controlled

    Not yet reported Sanofi 167 participants Est. completion 2014-04 13 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01700075

    Physical and Chemical Study of Atherosclerosis Mechanisms

    Not yet reported Nazarbayev University 97 participants Est. completion 2011-12 1 site
    Cardiovascular diseaseType 2 diabetes Other conditions: Atherosclerosis of Femoral Artery
    View official trial listing →
  • Completed NCT NCT01702298

    A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)

    Not yet reported Merck Sharp & Dohme LLC 42 participants Est. completion 2013-05-29 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01704261

    Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Combination Therapy With Glimepiride and Metformin (MK-3102-022)

    Not yet reported Merck Sharp & Dohme LLC 307 participants Est. completion 2014-12-23 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01708902

    Study to Compare the Efficacy and Safety of Administration of the Fix Dose Combination of Linagliptin Plus Metformin in Drug naïve Type 2 Patients

    Not yet reported Boehringer Ingelheim 876 participants Est. completion 2014-04 56 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01709305

    A Study of the Safety and Efficacy of Glimepiride, Gliclazide, Repaglinide or Acarbose When Added to Sitagliptin + Metformin Combination Therapy in Chinese Participants With Diabetes (MK-0431-313)

    Not yet reported Merck Sharp & Dohme LLC 5570 participants Est. completion 2015-04-17 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01710527

    BE Study of Metformin GSK 500mg

    Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-05-18
    Other conditions: Diabetic Foot
    View official trial listing →
  • Completed NCT NCT01710540

    BE Study of Metformin GSK 850mg

    Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-08
    Other conditions: Diabetic Foot
    View official trial listing →
  • Completed NCT NCT01710553

    BE STUDY OF METFORMIN GSK 1000mg

    Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-07
    Other conditions: Diabetic Foot
    View official trial listing →
  • Completed NCT NCT01711320

    Effect of Omeprazole on Metformin

    Not yet reported Xijing Hospital 20 participants Est. completion 2012-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT01717482

    Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer

    Not yet reported Mayo Clinic 6 participants Est. completion 2019-05-22 1 site
    Other conditions: Lung Neoplasms, Carcinoma, Non-Small-Cell Lung
    View official trial listing →
  • Status unknown NCT NCT01717911

    ß-Cell Function and Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients With Moderate Hyperglycemia

    Not yet reported Taipei Veterans General Hospital, Taiwan 160 participants Est. completion 2018-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01718093

    A Pilot Study to Assess the Glucose Lowering Effect of Metformin and Sitagliptin in Adolescents With Type 1 Diabetes

    Not yet reported Baylor College of Medicine 21 participants Est. completion 2015-12 1 site
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Withdrawn NCT NCT01718340

    Effectiveness of Metformin in Recurrent Miscarriage in a Woman With Hyperinsulinaemia

    Not yet reported Woman's Health University Hospital, Egypt Est. completion 2014-06 1 site Stand-alone
    Other conditions: Abortion, Habitual
    View official trial listing →
  • Completed NCT NCT01719003

    Safety and Efficacy Study of Empagliflozin and Metformin for 24 Weeks in Treatment Naive Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 1413 participants Est. completion 2014-12 190 sites Stand-alone
    Type 2 diabetes Other conditions: Hyperglycemia
    View official trial listing →
  • Completed NCT NCT01719614

    A Study to Explore Pharmacokinetic Interaction Between Rilpivirine and Metformin in Healthy Participants

    Not yet reported Janssen R&D Ireland 20 participants Est. completion 2013-01 1 site Stand-alone
    Other conditions: Healthy Participants
    View official trial listing →
  • Completed NCT NCT01720290

    Comparison of Repaglinide and Metformin Administered Alone or in Combination in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 150 participants Est. completion 2003-02-25 3 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01725126

    To Investigate the Safety, Tolerability and Pharmacodynamics of GSK2890457 in Healthy Volunteers and Subjects With Type 2 Diabetes

    Not yet reported GlaxoSmithKline 53 participants Est. completion 2013-09-12 3 sites Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT01725490

    The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study

    Not yet reported Yonsei University 34 participants Est. completion 2020-08-30 1 site Stand-alone
    Other conditions: Familial Adenomatous Polyposis
    View official trial listing →
  • Terminated NCT NCT01725672

    Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers

    Not yet reported GlaxoSmithKline 20 participants Est. completion 2013-08-21 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01726764

    Interaction Between St John's Wort and Metformin?

    Not yet reported University of Southern Denmark 20 participants Est. completion 2014-05 1 site Stand-alone
    Type 2 diabetes Other conditions: Depression
    View official trial listing →
  • Completed NCT NCT01728740

    Bioequivalence Study for Acarbose / Metformin FDC

    Not yet reported Bayer 40 participants Est. completion 2012-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Completed NCT NCT01729156

    Effects of Metformin on Hepatic FFA Metabolism

    Not yet reported Lars Christian Gormsen 36 participants Est. completion 2017-05-05
    Type 2 diabetes Other conditions: Dyslipidemia
    View official trial listing →
  • Completed NCT NCT01729403

    A Study of The Effect of Aleglitazar on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin

    Not yet reported Hoffmann-La Roche 57 participants Est. completion 2013-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01733459

    Efficacy and Safety of DLBS3233 in Subjects With Polycystic Ovary Syndrome (PCOS)

    Not yet reported Dexa Medica Group 124 participants Est. completion 2018-06 2 sites Stand-alone
    Other conditions: Polycystic Ovary Syndrome (PCOS)
    View official trial listing →
  • Withdrawn NCT NCT01733836

    Prostate Cancer Active Surveillance Metformin Trial

    Not yet reported University Health Network, Toronto Est. completion 2014-10 1 site Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01734785

    Safety and Efficacy of the Combination of Empagliflozin and Linagliptin Compared to Linagliptin Alone Over 24 Weeks in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 607 participants Est. completion 2015-03-23 90 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01747083

    Food-Effect Bioavailability Study of FDC(Gemigliptin/Metformin HCl Sustained Release) 50/1000mg(25/500mg x 2tablets)

    Not yet reported LG Life Sciences 24 participants Est. completion 2013-04 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01751321

    Glucose Variability With DPP-4 Inhibition

    Not yet reported Research Clinical Centre of the Russian Railways, JSC 50 participants Est. completion 2013-10
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01754142

    Korean Post-marketing Surveillance for Kombiglyze XR®

    AstraZeneca 755 participants Est. completion 2016-09-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01755156

    A Study to Evaluate the Safety, Tolerability, and Efficacy of the Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Therapy (MK-3102-024)

    Not yet reported Merck Sharp & Dohme LLC 402 participants Est. completion 2016-03-16 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01755468

    Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Pilot Study)

    Not yet reported Mount Sinai Hospital, Canada 24 participants Est. completion 2017-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01755494

    A Bioequivalence Study of the Fixed Dose Combinations of Saxagliptin/Metformin XR Relative to Co-Administration

    Not yet reported AstraZeneca 64 participants Est. completion 2013-04 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01756105

    Efficacy of Metformin in Achieving Glycaemia Goals as Recommended for the Treatment of Gestational Diabetes in Non Obese Women

    Not yet reported University Hospital, Strasbourg, France 84 participants Est. completion 2018-06 5 sites Stand-alone
    Other conditions: Gestational Diabetes, Metformin, Treatment, Oxidative Stress
    View official trial listing →
  • Completed NCT NCT01756417

    A Study to Investigate Whether Pharmacokinetic and Pharmacodynamic Interactions Exist Between Metformin and Canagliflozin (JNJ-28431754) in Healthy Volunteers

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 18 participants Est. completion 2007-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01757587

    Galvus (Vildagliptin) vs Placebo in Combination With Metformin and Insulin

    Not yet reported Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète 39 participants Est. completion 2015-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01759823

    Bone Marrow Derived Stem Cell Transplantation in T2DM

    Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2015-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01760447

    A Pooled Analysis of the Safety and Efficacy of MK-0431A and MK-0431A XR in Pediatric Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin) (MK-0431A-170/MK-0431A-289)

    Not yet reported Merck Sharp & Dohme LLC 223 participants Est. completion 2019-09-17 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01762046

    Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans

    Not yet reported Massachusetts General Hospital 1033 participants Est. completion 2025-12 3 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01763346

    Beta Cell Restoration Through Fat Mitigation

    Not yet reported University of Southern California 88 participants Est. completion 2018-06 1 site
    PrediabetesType 2 diabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT01765894

    Influence of Moderate Exercise on Blood Glucose in Type 2 Diabetics and Healthy Controls

    University of Copenhagen 24 participants Est. completion 2013-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01765946

    Metformin and Longevity Genes in Prediabetes

    Not yet reported University of Padova 38 participants Est. completion 2013-03 1 site Stand-alone
    Prediabetes Other conditions: Insulin Resistance, Aging, Inflammation
    View official trial listing →
  • Completed NCT NCT01766778

    Early add-on Vildagliptin in Patients With Type 2 Diabetes Inadequately Controlled by Metformin

    Not yet reported Novartis Pharmaceuticals 117 participants Est. completion 2015-10-22 4 sites
    Other conditions: Type-2 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01767389

    Glucagon-like Peptide (GLP) Utilization and Safety

    GlaxoSmithKline 1 participants Est. completion 2013-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01768559

    Efficacy and Safety of Lixisenatide Versus Insulin Glulisine on Top of Insulin Glargine With or Without Metformin in Type 2 Diabetic Patients

    Not yet reported Sanofi 894 participants Est. completion 2014-12 199 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01771185

    Metabolic Effects of Gastrointestinal Surgery in T2DM

    Not yet reported University of Sao Paulo 24 participants Est. completion 2013-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01775579

    Evaluating a Pharmacokinetic Drug Interaction Between Metformin Hydrochloride and Rosuvastatin Calcium

    Not yet reported Hanmi Pharmaceutical Company Limited 36 participants Est. completion 2013-06 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01775813

    The Health Influences of Puberty (HIP) Study

    Not yet reported University of Colorado, Denver 104 participants Est. completion 2018-05-31 1 site Stand-alone
    Type 2 diabetes Other conditions: Obesity, Insulin Resistance, Gonadal Dysfunction
    View official trial listing →
  • Completed NCT NCT01778049

    Linagliptin as Add on Therapy to Empagliflozin 10 mg or 25 mg With Background Metformin in Patient With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim 708 participants Est. completion 2015-03 114 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01778244

    Metformin for Treatment of Antipsychotic-induced Dyslipidemia

    Not yet reported Central South University 162 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Dyslipidemia
    View official trial listing →
  • Completed NCT NCT01779362

    RISE Adult Medication Study

    Not yet reported RISE Study Group 267 participants Est. completion 2019-08 4 sites
    PrediabetesType 2 diabetes
    View official trial listing →
  • Completed NCT NCT01779375

    RISE Pediatric Medication Study

    Not yet reported RISE Study Group 91 participants Est. completion 2018-04 4 sites
    PrediabetesType 2 diabetes
    View official trial listing →
  • Completed NCT NCT01780051

    A Pharmacokinetic Study to Compare Co-administration of Repaglinide and Metformin HCl to Administration of Combination Preparation of Those Two Components

    Not yet reported Dalim BioTech Co., Ltd. 48 participants Est. completion 2013-04 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01781754

    Changes in Mitochondrial Uncoupling Protein 2 (UCP2) Messenger RNA(mRNA) in Type 2 Diabetes (T2DM) Patients

    Tel-Aviv Sourasky Medical Center 50 participants Est. completion 2014-01 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01784380

    The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome

    Zhongshan Bo Ai Hospital 1159 participants Est. completion 2012-10 2 sites
    Other conditions: The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;, At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;, 534 Patients in the Cases Group and 580 Women in the Control Group Received no Measures, While 579 Patients Received Drugs;, The Investigators Monitored Basic Indexes in Blood of All the Subjects in This Suvey,and Also Monitored Indexes of 579 Patients After Treatment.
    View official trial listing →
  • Completed NCT NCT01785043

    Differences in Endothelial Function Amongst Sitagliptin and Liraglutide Users

    Not yet reported Anna Cruceta 13 participants Est. completion 2014-09 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01786707

    Autologous Stem Cell and Hyperbaric Oxygen Therapy in Type 2 Diabetes Mellitus

    Not yet reported, Not yet reported Rodolfo Alejandro 2 participants Est. completion 2013-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01787396

    Phase III Trial to Evaluate the Efficacy and Safety of Initial Combination Therapy With Gemigliptin 50mg q.d and Metformin q.d

    Not yet reported LG Life Sciences 433 participants Est. completion 2015-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01789957

    Extension Study for 2993-112

    Not yet reported AstraZeneca 225 participants Est. completion 2004-06 226 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01791647

    Myo-inositol Versus Metformin in Obese Women With Polycystic Ovary Syndrome

    Not yet reported Catholic University of the Sacred Heart 40 participants Est. completion 2012-12 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01792830

    Efficacy and Safety of a Glargine-based Hospital Discharge Algorithm in Coronary Artery Bypass Graft (CABG) Patients

    Not yet reported Emory University 175 participants Est. completion 2014-02 3 sites
    Other conditions: Poor Glycemic Control
    View official trial listing →
  • Completed NCT NCT01796028

    Metformin-Docetaxel Association in Metastatic Hormone-refractory Prostate Cancer

    Not yet reported Centre Antoine Lacassagne 100 participants Est. completion 2018-05-31 1 site Stand-alone
    Other conditions: Prostatic Neoplasms
    View official trial listing →
  • Completed NCT NCT01797523

    A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma

    Not yet reported M.D. Anderson Cancer Center 62 participants Est. completion 2026-02-04 6 sites Stand-alone
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT01798706

    Efficacy and Safety of Lixisenatide Versus Placebo on Top of Basal Insulin and/or Oral Antidiabetic Treatment in Older Type 2 Diabetic Patients

    Not yet reported Sanofi 350 participants Est. completion 2015-02 83 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01798875

    PCOS, Therapy and Markers of Cardiovascular Risk

    Not yet reported Medical University of Gdansk 50 participants Est. completion 2015-12 1 site
    Other conditions: PCOS
    View official trial listing →
  • Terminated NCT NCT01799057

    The Effects of Metformin on Functional Capacity in Individuals With Peripheral Artery Disease-Related Intermittent Claudication

    Not yet reported Baker Heart and Diabetes Institute 2 participants Est. completion 2014-12 1 site Stand-alone
    Alcohol use disorder Other conditions: Peripheral Arterial Disease
    View official trial listing →
  • Completed NCT NCT01800227

    Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fasting Conditions

    Not yet reported Torrent Pharmaceuticals Limited 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01800240

    Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fed Conditions

    Not yet reported Torrent Pharmaceuticals Limited 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01804049

    Metformin and Muscle in Insulin-resistant Older Veterans

    Not yet reported, Not yet reported VA Office of Research and Development 120 participants Est. completion 2018-08-31 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT01804842

    Assessing the Effect of Met DR on Plasma Glucose and PK in Subjects With T2DM

    Not yet reported, Not yet reported Elcelyx Therapeutics, Inc. 26 participants Est. completion 2013-04 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01809327

    A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise

    Not yet reported Janssen Research & Development, LLC 1186 participants Est. completion 2014-12-02 129 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01811485

    Study of Efficacy and Safety LMF237 in Patients With Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Vildagliptin Monotherapy

    Not yet reported Novartis Pharmaceuticals 171 participants Est. completion 2014-02 30 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01811953

    Equivalence of Resorption of Empagliflozin/Metformin Administered as Combination Tablet Compared With Empagliflozin/Metformin as Single Tablets Administered Together

    Not yet reported Boehringer Ingelheim 48 participants Est. completion 2013-05 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01813929

    Effect of Metformin on Vascular and Mitochondrial Function in Type 1 Diabetes

    Not yet reported University of Colorado, Denver 23 participants Est. completion 2017-03-24 1 site Stand-alone
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT01814748

    A Study of the Safety and Efficacy of Omarigliptin (MK-3102) in ≥18 and <45 Year-Old Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control (MK-3102-028)

    Not yet reported Merck Sharp & Dohme LLC 203 participants Est. completion 2015-09-14 Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT01816659

    An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin

    Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2014-08 1 site Stand-alone
    Other conditions: Colorectal Carcinoma
    View official trial listing →
  • Terminated NCT NCT01817777

    An Open Study to Evaluate Whether Pack Size Affects Compliance of Metformin Treatment in Subjects With Type II Diabetes

    Not yet reported GlaxoSmithKline 31 participants Est. completion 2014-02 7 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01819129

    Efficacy and Safety of FIAsp Compared to Insulin Aspart in Combination With Insulin Glargine and Metformin in Adults With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 881 participants Est. completion 2015-01-22 144 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01819272

    Assessing the Efficacy, Safety, and Tolerability of Met DR in Subjects With T2DM Over 12 Weeks

    Not yet reported Elcelyx Therapeutics, Inc. 240 participants Est. completion 2013-09 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01822548

    Effect of Vildagliptin vs. Glibenclamide on Circulating Endothelial Progenitor Cell Number Type 2 Diabetes

    Not yet reported Azienda Ospedaliero-Universitaria di Parma 64 participants Est. completion 2015-01 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01825798

    Treatment of Overweight Induced by Antipsychotic Medication in Young People With Autism Spectrum Disorders (ASD)

    Not yet reported Holland Bloorview Kids Rehabilitation Hospital 60 participants Est. completion 2015-10 4 sites Stand-alone
    Other conditions: Overweight, Autism Spectrum Disorder
    View official trial listing →
  • Completed NCT NCT01827280

    Acute and Short-term Chronic Effects of Galvus (Vildagliptin) in Diabetes Type 2 Obese Women

    Not yet reported Rio de Janeiro State University 40 participants Est. completion 2016-11 1 site Stand-alone
    Other conditions: 1- Microvascular Function, 2-oxidative Stress, 3-inflammation
    View official trial listing →
  • Completed NCT NCT01831661

    Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fasting Condition

    Not yet reported IPCA Laboratories Ltd. 48 participants Est. completion 2013-02 1 site Stand-alone
    Other conditions: Fasting
    View official trial listing →
  • Completed NCT NCT01831674

    Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fed Condition

    Not yet reported IPCA Laboratories Ltd. 48 participants Est. completion 2013-02 1 site Stand-alone
    Other conditions: Fasting
    View official trial listing →
  • Completed NCT NCT01832181

    MiTy Kids (Metformin in Women With Type 2 Diabetes in Pregnancy Kids Trial)

    Mount Sinai Hospital, Canada 287 participants Est. completion 2021-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01834274

    Comparison of Fasiglifam (TAK-875) With Sitagliptin When Used in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Takeda 96 participants Est. completion 2014-03 104 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01840007

    Pilot Study Evaluating the Efficacy and Safety of Metformin in Melanoma

    Not yet reported Centre Hospitalier Universitaire de Nice 20 participants Est. completion 2015-11-18 2 sites Stand-alone
    Other conditions: Metastatic Melanoma (Stage IIIC Non-résécable or no Surgically Curable or Stage IV With Classification AJCC)
    View official trial listing →
  • Completed NCT NCT01841697

    Study to Evaluate the Safety and Efficacy of the Addition of Omarigliptin (MK-3102) Compared With the Addition of Sitagliptin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-026)

    Not yet reported Merck Sharp & Dohme LLC 642 participants Est. completion 2014-11-17 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01842620

    OXEMET™ 1000 mg Coated Tablets (Metformin Hydrochloride) Bioequivalence Study. OXEMET (TM) is a Trademark of the GlaxoSmithKline Group of Companies. GLAFORNIL(TM) is a Trademark of Merck.

    Not yet reported GlaxoSmithKline 25 participants Est. completion 2013-05-04 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01844531

    Bioequivalence of Empagliflozin and Metformin Given as a Fixed Dose Combination Compared to Single Tablets

    Not yet reported Boehringer Ingelheim 24 participants Est. completion 2013-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01845077

    Relative Bioavailability of 2 Fixed Dose Combinations of Linagliptin/Metformin Compared With Single Tablets

    Not yet reported Boehringer Ingelheim 72 participants Est. completion 2013-08 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01845831

    Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes

    Not yet reported Emory University 292 participants Est. completion 2016-04 5 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01849276

    Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML

    Not yet reported Northwestern University 2 participants Est. completion 2016-01-21 1 site Stand-alone
    Other conditions: Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Erythroleukemia (M6a), Adult Pure Erythroid Leukemia (M6b), Blastic Phase Chronic Myelogenous Leukemia, Recurrent Adult Acute Myeloid Leukemia, Untreated Adult Acute Myeloid Leukemia
    View official trial listing →
  • Completed NCT NCT01849289

    A Trial Comparing Efficacy and Safety of Insulin Degludec and Insulin Glargine in Insulin naïve Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 833 participants Est. completion 2014-05-15 81 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01850615

    Efficacy and Safety of FIAsp in a Basal-bolus Regimen Versus Basal Insulin Therapy, Both in Combination With Metformin in Adult Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 323 participants Est. completion 2014-11-17 58 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT01855763

    Metformin Treatment in Gestational Diabetes and Noninsulin Dependent Diabetes in Pregnancy in a Developing Country

    Not yet reported, Not yet reported Dow University of Health Sciences 300 participants Est. completion 2013-12 Stand-alone
    Type 2 diabetes Other conditions: Gestational Diabetes, Pregnancy
    View official trial listing →
  • Completed NCT NCT01856907

    Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM

    Not yet reported Woman's 36 participants Est. completion 2017-09-28 1 site Stand-alone
    Other conditions: Disorder of Glucose Regulation
    View official trial listing →
  • Completed NCT NCT01857609

    Clinical Trial to Investigate the Effect of Proton Pump Inhibitor on the Pharmacokinetics and Pharmacodynamics of Metformin

    Not yet reported Seoul National University Hospital 24 participants Est. completion 2012-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01859793

    Effects of Sitagliptin on Endothelial Function in Type 2 Diabetes on Background Metformin Therapy

    Not yet reported Medical College of Wisconsin 38 participants Est. completion 2016-07 1 site
    Other conditions: Diabetes, Atherosclerosis
    View official trial listing →
  • Terminated NCT NCT01863667

    A Study to Evaluate the Safety and Efficacy of Omarigliptin (MK-3102) Compared With Glimepiride in Participants With Type 2 Diabetes Mellitus for Whom Metformin is Inappropriate (MK-3102-027)

    Not yet reported Merck Sharp & Dohme LLC 65 participants Est. completion 2014-04-03
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01864096

    The Metformin Active Surveillance Trial (MAST) Study

    Not yet reported University Health Network, Toronto 408 participants Est. completion 2024-08 12 sites Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT01864174

    Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

    Not yet reported Bristol-Myers Squibb 1736 participants Est. completion 2016-06-01 156 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01864681

    Combination of Metformin With Gefitinib to Treat NSCLC

    Not yet reported Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 224 participants Est. completion 2018-06-04 1 site Stand-alone
    Other conditions: NSCLC, EGFR Gene Amplification, Advanced Cancer, Stage IIIB NSCLC, Stage IV NSCLC
    View official trial listing →
  • Completed NCT NCT01866462

    Pilot Study of the Effect of MN-504 Cobiotic Formulation on the Efficacy and Tolerability of Metformin

    Not yet reported NuMe Health 10 participants Est. completion 2014-07 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01867502

    Effects of Vildagliptin Versus Glibenclamide on Glycemia After Exercise in Patients With Type 2 Diabetes

    Not yet reported Hospital de Clinicas de Porto Alegre 20 participants Est. completion 2015-08 1 site
    Type 2 diabetes Other conditions: Hypoglycemic Agents, Diabetic Blood Glucose Monitoring, Exercise
    View official trial listing →
  • Completed NCT NCT01868542

    A Trial Comparing the Glycaemic Control of Levemir® Administered Once Daily According to Two Insulin Detemir Titration Algorithms After 20 Weeks in Subjects With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin Treatment With or Without Other Anti-diabetic Drugs (OADs)

    Not yet reported Novo Nordisk A/S 46 participants Est. completion 2015-05 6 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01869621

    Study of Metformin Pharmacogenetics in Twins

    Not yet reported University of Southern Denmark 34 participants Est. completion 2014-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01871415

    A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy

    Not yet reported Hoffmann-La Roche 7 participants Est. completion 2013-08 7 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01871558

    Vildagliptin/Metformin in T2DM Patients Starting Basal Insulin

    Not yet reported Novartis Pharmaceuticals 42 participants Est. completion 2015-02 19 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01874080

    Bioequivalence Study

    Not yet reported AstraZeneca 56 participants Est. completion 2013-07 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT01876992

    Metformin at the Cellular Level and Dosing for Diabetes Mellitus (DM)

    Not yet reported Johns Hopkins University 10 participants Est. completion 2015-06 1 site Stand-alone
    Prediabetes Other conditions: Diabetes, Obesity
    View official trial listing →
  • Completed NCT NCT01877564

    A Randomized Pilot Study to Evaluate the Effects of a Short Course of Metformin Versus No Therapy in the Period Prior to Hysterectomy for Grade 1-2 Adenocarcinoma of the Endometrium in Obese Non-Diabetic Women

    Not yet reported University of Arkansas 10 participants Est. completion 2017-07-10 1 site Stand-alone
    Other conditions: Adenocarcinoma of the Endometrium
    View official trial listing →
  • Completed NCT NCT01879293

    Metformin Reduces Left Ventricular Mass in Patients With Ischemic Heart Disease

    Not yet reported Wuhan General Hospital of Guangzhou Military Command 120 participants Est. completion 2015-08 1 site Stand-alone
    Other conditions: Left Ventriclar Mass
    View official trial listing →
  • Completed NCT NCT01881828

    Metformin Therapy for Overweight Adolescents With Type 1 Diabetes

    Not yet reported Jaeb Center for Health Research 164 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT01882907

    Safety and Efficacy Study to Compare Vildagliptin to Pioglitazone as Adding on Metformin in Type 2 Diabetes

    Not yet reported Pusan National University Hospital 287 participants Est. completion 2013-03 15 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01884558

    A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Metformin

    Not yet reported Astellas Pharma Global Development, Inc. 24 participants Est. completion 2013-02 1 site Stand-alone
    Other conditions: Pharmacokinetics of Isavuconazole, Pharmacokinetics of Metformin, Healthy Subjects
    View official trial listing →
  • Completed NCT NCT01885013

    Myocet + Cyclophosphamide + Metformin Vs Myocet + Cyclophosphamide in 1st Line Treatment of HER2 Neg. Metastatic Breast Cancer Patients

    Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 126 participants Est. completion 2015-05 25 sites Stand-alone
    Other conditions: Human Epidermal Growth Factor 2 Negative Carcinoma of Breast
    View official trial listing →
  • Completed NCT NCT01885260

    Safety, Tolerability and Efficacy of ISIS-GCGRRx in Type 2 Diabetes

    Not yet reported Ionis Pharmaceuticals, Inc. 77 participants Est. completion 2014-11 24 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01889667

    Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Oral Bedtime Doses of ORMD-0801 in Adult Patients With Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Oramed, Ltd. 30 participants Est. completion 2013-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01889706

    Metformin Therapy in Type 1 Diabetes Mellitus.

    Poznan University of Medical Sciences 200 participants Est. completion 2014-02 1 site
    Other conditions: Loss of Control of Diabetes
    View official trial listing →
  • Completed NCT NCT01890122

    Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 Diabetes

    Not yet reported Takeda 647 participants Est. completion 2015-10 45 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01890629

    Effects of Gemigliptin Versus Sitagliptin or Glimepiride With Metformin on Glucose Variability(MAGE, Glucose SD) Patients With Type 2 DM(STABLE Study)

    Not yet reported LG Life Sciences 69 participants Est. completion 2014-08 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01892020

    Investigating Efficacy and Safety of Biphasic Insulin Aspart 50 Twice Daily Versus Biphasic Human Insulin 50 Twice Daily Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus

    Not yet reported Novo Nordisk A/S 161 participants Est. completion 2014-05 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01892254

    Incretin Effect in PCOS Women

    Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2017-11-23 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT01895569

    Triple Therapy in Type 2 Diabetic Patients

    Not yet reported University of Pavia 64 participants Est. completion 2016-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01899430

    Polycystic Ovary Syndrome and Liraglutide

    Not yet reported University Medical Centre Ljubljana 32 participants Est. completion 2013-04 1 site
    Other conditions: PCOS, Obesity
    View official trial listing →
  • Terminated NCT NCT01901224

    Metformin, Muscle Energetics, and Vascular Function in Older Adults With Peripheral Artery Disease

    Not yet reported Brigham and Women's Hospital 2 participants Est. completion 2015-06 1 site Stand-alone
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Completed NCT NCT01903356

    A Regulatory Requirement Non Interventional Study to Monitor Safety and Effectiveness of Trajenta Duo in Type 2 Diabetes Patients in Korea

    Boehringer Ingelheim 724 participants Est. completion 2017-06-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT01905046

    Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer

    Not yet reported Alliance for Clinical Trials in Oncology 86 participants Est. completion 2026-11 27 sites Stand-alone
    Other conditions: Atypical Ductal Breast Hyperplasia, BRCA1 Mutation Carrier, BRCA2 Mutation Carrier, Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in Situ
    View official trial listing →
  • Completed NCT NCT01907854

    Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin

    Not yet reported Novo Nordisk A/S 407 participants Est. completion 2015-06-15 106 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01909141

    Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS

    Not yet reported Cairo University 100 participants Est. completion 2014-04 1 site
    Other conditions: Polycystic Ovary Syndrome, Infertility
    View official trial listing →
  • Withdrawn NCT NCT01910246

    Cardiovascular Effects of Metformin on Obesity

    Not yet reported University of California, San Francisco Est. completion 2016-10 1 site Stand-alone
    Other conditions: Insulin Resistance
    View official trial listing →
  • Terminated NCT NCT01910441

    Comparison of Vildagliptin vs. Glimepiride on Glucose Variability in Metformin Uncontrolled Type 2 Diabetic Patients

    Not yet reported Novartis Pharmaceuticals 95 participants Est. completion 2014-09 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01911468

    Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin

    Not yet reported University Medical Centre Ljubljana 36 participants Est. completion 2013-04 1 site
    Other conditions: PCOS, Obesity
    View official trial listing →
  • Withdrawn NCT NCT01915264

    GLucobay M - Evaluation Of Safety and Effectiveness in Type 2 Diabetes Not Well Controlled on Monotherapy in Real Life Practice

    Bayer Est. completion 2017-03
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01915550

    Metformin as Adjuvant to Insulin Therapy in Insulin-resistant Diabetes Mellitus With Pregnancy

    Not yet reported Ain Shams University 90 participants Est. completion 2013-02 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01917656

    Efficacy and Safety of Liraglutide Versus Sulphonylurea Both in Combination With Metformin During Ramadan in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 343 participants Est. completion 2014-09-04 41 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01918865

    Safety, Tolerability, and Efficacy of ISIS-PTP1BRx in Type 2 Diabetes

    Not yet reported Ionis Pharmaceuticals, Inc. 92 participants Est. completion 2015-02 21 sites Stand-alone
    Type 2 diabetes Other conditions: Obese
    View official trial listing →
  • Completed NCT NCT01923181

    Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 632 participants Est. completion 2014-12-11 103 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT01926769

    A Phase II Study to Determine the Safety and Efficacy of Second-line Treatment With Metformin and Chemotherapy (FOLFOX6 or FOFIRI) in the Second Line Threatment of Advanced Colorectal Cancer

    Not yet reported Gachon University Gil Medical Center 2 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Previously Treated Advanced Colorectal Cancer
    View official trial listing →
  • Completed NCT NCT01929512

    Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 750mg and Rosuvastatin 20mg

    Not yet reported Hanmi Pharmaceutical Company Limited 72 participants Est. completion 2013-08 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT01929811

    NeoMET Study in Neoadjuvant Treatment of Breast Cancer

    Not yet reported Shanghai Jiao Tong University School of Medicine 92 participants Est. completion 2020-06 2 sites Stand-alone
    Other conditions: pCR Rate, BCT Rate, Safety
    View official trial listing →
  • Completed NCT NCT01929863

    Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 in Type 2 Diabetes Patients Taking Metformin

    Not yet reported GlaxoSmithKline 16 participants Est. completion 2013-11-21 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01930188

    Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 1231 participants Est. completion 2015-10-12 141 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT01930864

    Metformin Plus Irinotecan for Refractory Colorectal Cancer

    Not yet reported Barretos Cancer Hospital 41 participants Est. completion 2020-12-01 2 sites Stand-alone
    Other conditions: Colorectal Neoplasms, Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT01933256

    Study of Subcutaneous Doses of HIP2B in Subjects With Type 2 Diabetes Mellitus Treated With Metformin

    Not yet reported CureDM 32 participants Est. completion 2014-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01933672

    Study Of Two Dosing Regimens Of PF-04937319 Compared To An Approved Agent (Sitagliptin) In Patients With Type 2 Diabetes

    Not yet reported Pfizer 33 participants Est. completion 2014-03 8 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01935804

    Effect of Pioglitazone Versus Metformin on Bone Health in Postmenopausal Women With Type 2 Diabetes

    Not yet reported King Abdulaziz University 440 participants Est. completion 2014-01 1 site
    Type 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders
    View official trial listing →
  • Completed NCT NCT01937598

    Antidiabetic Effects of Adding a DPP-4 Inhibitor to Pre-Existing Treatment With an Incretin Mimetic in Patients With T2D

    Not yet reported Michael A. Nauck 16 participants Est. completion 2015-06 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01940302

    Dietary Supplement of LEHEL for the Patients With Type 2 Diabetes

    Not yet reported Shaoguan University 71 participants Est. completion 2014-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01944618

    forREAL: FORXIGA PRESCRIPTION EVENT MONITORING PROGRAM (PEMP)

    AstraZeneca 5000 participants Est. completion 2015-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01947153

    Two-way Crossover Study in Healthy Male and Female Subjects to Evaluate the Bioequivalence of Jentadueto®.

    Not yet reported Boehringer Ingelheim 36 participants Est. completion 2014-01 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01947790

    Pioglitazone Regress Left Ventricular Mass in Type 2 Diabetes With Ischeamia Heart Disease

    Not yet reported Xiang Guang-da 120 participants Est. completion 2015-07 2 sites
    Other conditions: LVM, Type 2 Diabetic Patients With IHD, Endothelial Function
    View official trial listing →
  • Withdrawn NCT NCT01951183

    A Study of RO6811135 in Patients With Type 2 Diabetes Who Are Inadequately Controlled With Metformin

    Not yet reported Hoffmann-La Roche Est. completion 2013-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01952145

    A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide Versus Insulin Glargine in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Novo Nordisk A/S 557 participants Est. completion 2014-11-04 91 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Withdrawn NCT NCT01954732

    Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery

    Not yet reported Case Comprehensive Cancer Center Est. completion 2015-03 Stand-alone
    Other conditions: Stage IA Pancreatic Cancer, Stage IB Pancreatic Cancer, Stage IIA Pancreatic Cancer, Stage IIB Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT01956305

    Randomized, Placebo-controlled, 2 Period, Single-blind, Sequential, Multiple Ascending Dose Study

    Not yet reported Daiichi Sankyo 48 participants Est. completion 2014-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01956929

    Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism.

    Not yet reported Mayo Clinic 12 participants Est. completion 2016-03 1 site Stand-alone
    Other conditions: Insulin Resistance, Prediabetic State
    View official trial listing →
  • Completed NCT NCT01958671

    A Study of the Efficacy and Safety of Ertugliflozin Monotherapy in the Treatment of Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control Despite Diet and Exercise (MK-8835-003, VERTIS MONO)

    Not yet reported Merck Sharp & Dohme LLC 461 participants Est. completion 2016-07-28 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01961388

    Study to Assess the Dietary Carbohydrate Content of Indian Diabetics With Special Therapeutic View on Effectiveness of Acarbose and Metformin Monotherapy

    Bayer Est. completion 2017-06
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01963130

    Does Vildagliptin Affect Portal Vein Pressure In Patients With Type 2 Diabetes Mellitus? A Cross Sectional Study

    Bezmialem Vakif University 97 participants Est. completion 2013-07 1 site
    Other conditions: Drug Mechanism, Drug Usage
    View official trial listing →
  • Completed NCT NCT01963663

    Metformin and Pioglitazone Effects on YKL-40 Concentrations in Type 2 Diabetes Patients

    Not yet reported Tehran University of Medical Sciences 84 participants Est. completion 2013-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01965509

    A PK/PD Study of Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 120 participants Est. completion 2013-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01965756

    Effect of Insulin Sensitizer Metformin on AD Biomarkers

    Not yet reported University of Pennsylvania 20 participants Est. completion 2017-04 1 site Stand-alone
    Other conditions: Alzheimer's Disease, Vascular Dementia, Dementia, Memory Impairment
    View official trial listing →
  • Completed NCT NCT01966978

    The Effect of Simple Basal Insulin Titration, Metformin Plus Liraglutide for Type 2 Diabetes With Very Elevated HbA1c - The SIMPLE Study

    Not yet reported University of Texas Southwestern Medical Center 157 participants Est. completion 2017-12 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01968265

    Safety, Tolerability and Efficacy of ISIS-GCCRRx in Type 2 Diabetes

    Not yet reported Ionis Pharmaceuticals, Inc. 38 participants Est. completion 2015-05 14 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01968317

    Megestrol Acetate Plus Metformin to Megestrol Acetate in Patients With Endometrial Atypical Hyperplasia or Early Stage Endometrial Adenocarcinoma

    Not yet reported Xiaojun Chen 150 participants Est. completion 2017-10 5 sites Stand-alone
    Other conditions: Endometrial Atypical Hyperplasia, Endometrial Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT01969318

    Efficacy and Safety Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 120 participants Est. completion 2012-11 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01970046

    A Phase III Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 360 participants Est. completion 2015-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01971034

    Treatment of Patients With Advanced Pancreatic Cancer After Gemcitabine Failure.

    Not yet reported Instituto do Cancer do Estado de São Paulo 41 participants 1 site Stand-alone
    Other conditions: Pancreatic Adenocarcinoma Advanced or Metastatic
    View official trial listing →
  • Completed NCT NCT01972724

    Efficacy of Pioglitazone in Participants With Inadequately Controlled Type 2 Diabetes Mellitus Treated With Stable Triple Oral Therapy

    Not yet reported Takeda 114 participants Est. completion 2016-10-17 9 sites Stand-alone
    Other conditions: Type II Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01973231

    Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 404 participants Est. completion 2014-11 61 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01973933

    Clinical Trial to Investigate the Pharmacokinetic/Pharmacodynamic Drug-Drug Interaction of Pyrimethamine and Metformin IR

    Not yet reported Seoul National University Hospital 20 participants 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT01974544

    Prevention and Treatment Of Diabetes Complications With Gastric Surgery or Intensive Medicines

    Not yet reported Pontificia Universidad Catolica de Chile 150 participants Est. completion 2016-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01980823

    Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer

    Not yet reported Columbia University 23 participants Est. completion 2022-12 1 site Stand-alone
    Other conditions: Breast Cancer, Breast Tumors, Cancer of Breast
    View official trial listing →
  • Completed NCT NCT01981525

    A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome

    Not yet reported National Cancer Institute (NCI) 26 participants Est. completion 2020-12-11 1 site Stand-alone
    Other conditions: Li-Fraumeni Syndrome
    View official trial listing →
  • Completed NCT NCT01984489

    Efficacy and Safety Study of SHR117887 in Combination With Metformin in Patients With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 120 participants Est. completion 2013-08 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01984606

    Efficacy and Safety of Empagliflozin Versus Sitagliptin in Patients With Type 2 Diabetes

    Not yet reported Boehringer Ingelheim Est. completion 2017-02
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01990469

    Efficacy and Safety of Gemigliptin 50mg qd Added in Patients With Type 2 Diabetes Inadequately Controlled on Glimepiride and Metformin

    Not yet reported LG Life Sciences 219 participants Est. completion 2015-04
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01992211

    Evaluating of Pharmacokinetic Profile of BCWP_C003 and Co-administration of Rosuvastatin and Metformin

    Not yet reported BC World Pharm Co. Ltd. 35 participants Est. completion 2017-07-10 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01995032

    L-citrulline and Metformin in Duchenne's Muscular Dystrophy

    Not yet reported University Hospital, Basel, Switzerland 47 participants Est. completion 2016-03 1 site Stand-alone
    Other conditions: Duchenne's Muscular Dystrophy (DMD)
    View official trial listing →
  • Terminated NCT NCT01996696

    Prevention of Metabolic Syndrome and Increased Weight Using Metformin Concurrent to Androgen Deprivation Therapy and Radiotherapy for Locally Advanced Adenocarcinoma of the Prostate

    Not yet reported AHS Cancer Control Alberta 83 participants Est. completion 2020-11 3 sites Stand-alone
    Other conditions: Prostatic Neoplasm
    View official trial listing →
  • Terminated NCT NCT01997775

    Metformin in Stage IV Lung Adenocarcinoma

    Not yet reported National Cheng-Kung University Hospital 13 participants Est. completion 2016-06 1 site Stand-alone
    Other conditions: Non-small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT01998113

    Glyburide and Metformin for the Treatment of Gestational Diabetes Mellitus. Systematic Review

    Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 2509 participants Est. completion 2014-05 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01999218

    Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)

    Not yet reported Merck Sharp & Dohme LLC 1326 participants Est. completion 2017-04-18 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01999686

    PCOS Treatment Using DLBS3233, Metformin, and Combination of Both

    Not yet reported Dexa Medica Group 186 participants Est. completion 2019-05 7 sites Stand-alone
    Other conditions: Polycystic Ovary Syndrome (PCOS), Insulin Resistance
    View official trial listing →
  • Completed NCT NCT02002221

    Study of Efficacy and Safety of Vildagliptin as add-on Insulin Therapy in T2DM Patients

    Not yet reported Novartis Pharmaceuticals 156 participants Est. completion 2015-02 31 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02004886

    A Study to Assess the Safety, Tolerability and Glucose-Lowering Efficacy of MK-0893 in Participants With Type 2 Diabetes Mellitus (MK-0893-005)

    Not yet reported Merck Sharp & Dohme LLC 74 participants Est. completion 2007-02-07 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02005419

    Metformin Combined With Gemcitabine as Adjuvant Therapy for Pancreatic Cancer After Curative Resection

    Not yet reported Xian-Jun Yu 300 participants Est. completion 2017-12 1 site Stand-alone
    Other conditions: Stage IA Pancreatic Adenocarcinoma, Stage IB Pancreatic Adenocarcinoma, Stage IIA Pancreatic Adenocarcinoma, Stage IIB Pancreatic Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT02006836

    Glycemic Responses to Majia Pomelos in Type 2 Diabetic Patients

    Not yet reported Huazhong University of Science and Technology 59 participants Est. completion 2013-12 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02007278

    Glycemic Excursions in Type 2 Diabetic Patients With Vildagliptin and Metformin Versus Vildagliptin and Glimepiride

    Not yet reported Novartis Pharmaceuticals 40 participants Est. completion 2016-02-22 8 sites
    Type 2 diabetes Other conditions: Hypoglycemia
    View official trial listing →
  • Completed NCT NCT02008682

    The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 368 participants Est. completion 2014-11 25 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02009488

    Treatment Differences Between Canagliflozin and Placebo in Insulin Secretion in Subjects With Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Janssen Research & Development, LLC 59 participants Est. completion 2017-01-03 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02011633

    Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 500mg and Rosuvastatin 10mg

    Not yet reported Hanmi Pharmaceutical Company Limited 72 participants Est. completion 2013-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02014740

    Effect of Liraglutide on Epicardial Fat in Subjects With Type 2 Diabetes

    Not yet reported University of Miami 100 participants Est. completion 2017-03 1 site Added to GLP-1
    Type 2 diabetes Other conditions: Overweight, Obesity
    View official trial listing →
  • Completed NCT NCT02017561

    Metformin in the Diastolic Dysfunction of Metabolic Syndrome

    Not yet reported Universidade do Porto 54 participants Est. completion 2019-12 1 site Stand-alone
    Metabolic syndrome Other conditions: Diastolic Dysfunction, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT02018731

    L-citrulline and Metformin in Becker's Muscular Dystrophy

    Not yet reported University Hospital, Basel, Switzerland 20 participants Est. completion 2015-12 1 site Stand-alone
    Other conditions: Becker's Muscular Dystrophy (BMD)
    View official trial listing →
  • Terminated NCT NCT02019979

    Metformin and Carbohydrate Restriction With Platinum Based Chemotherapy In Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NS-NSCLC)

    Not yet reported Beth Israel Medical Center 14 participants Est. completion 2016-12 4 sites Stand-alone
    Other conditions: Non-small Cell Lung Cancer Stage IIIB/IV, Non-small Cell Lung Cancer Metastatic, Nonsquamous Nonsmall Cell Neoplasm of Lung
    View official trial listing →
  • Terminated NCT NCT02020616

    A Study of the Safety and Effectiveness of LY3053102 in Participants With Type 2 Diabetes

    Not yet reported, Not yet reported Eli Lilly and Company 60 participants Est. completion 2015-02 5 sites Mixed
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02022007

    Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis

    Not yet reported Woman's 38 participants Est. completion 2016-10 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Disorder of Glucose Regulation
    View official trial listing →
  • Completed NCT NCT02022254

    Influence of Semaglutide on Pharmacokinetics and Pharmacodynamics of Warfarin and Pharmacokinetics of Metformin in Healthy Subjects

    Not yet reported Novo Nordisk A/S 24 participants Est. completion 2014-08-28 1 site Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes, Healthy
    View official trial listing →
  • Completed NCT NCT02024971

    Special Drug Use Surveillance of Pioglitazone/Metformin Hydrochloride Combination Tablets Survey on Long-term Use for Type 2 Diabetes Mellitus

    Takeda 1103 participants Est. completion 2013-11
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02025907

    A Study to Evaluate the Efficacy and Safety of the Addition of Canagliflozin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin and Sitagliptin

    Not yet reported Janssen Research & Development, LLC 218 participants Est. completion 2015-09 57 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02026310

    Efficacy/Safety Study of Glimepiride to Type 2 Diabetes Patients Based on Metformin And Basal Insulin Treatment

    Not yet reported Qifu Li 40 participants Est. completion 2015-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02026817

    Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 750mg and Rosuvastatin 10mg

    Not yet reported Hanmi Pharmaceutical Company Limited 36 participants Est. completion 2014-01 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT02026869

    Vaginal Administration of Metformin in PCOS Patients.

    Not yet reported Assiut University 200 participants Est. completion 2014-02 1 site
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT02027103

    Metformin and Pioglitazone Effects on Fetuin-A and Osteoprotegrin Concentrations in Type 2 Diabetes Patients

    Not yet reported Tehran University of Medical Sciences 102 participants Est. completion 2012-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02027753

    Efficacy and Safety of Insulin Glargine in Patients With Type 2 Diabetes With Inadequate Control on DPP-4 Inhibitor Therapy

    Not yet reported Sanofi 109 participants Est. completion 2015-04 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02028221

    Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk

    Not yet reported University of Arizona 151 participants Est. completion 2022-06-14 1 site Stand-alone
    Other conditions: Breast Cancer Prevention
    View official trial listing →
  • Completed NCT NCT02028689

    Metformin and Furosemide Drug-Drug Interaction Study

    Not yet reported Ardea Biosciences, Inc. 23 participants Est. completion 2014-01 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02028767

    Bioequivalence Study in Healthy Volunteers for Empagliflozin/Metformin Fixed Dose Combination Compared to Separate Tablets

    Not yet reported Boehringer Ingelheim 32 participants Est. completion 2014-02 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT02029846

    Glycemia in Diabetic Elders Trial

    Not yet reported Johns Hopkins University 2 participants Est. completion 2017-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02033876

    Ursodiol on Insulin Sensitivity, Gastric Emptying and Body Weight With Type 2 Diabetes on Metformin

    Not yet reported Mayo Clinic 24 participants Est. completion 2017-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02033889

    A Study To Evaluate The Efficacy And Safety Of Ertugliflozin In Participants With Type 2 Diabetes Mellitus And Inadequate Glycemic Control On Metformin Monotherapy (MK-8835-007).

    Not yet reported Merck Sharp & Dohme LLC 621 participants Est. completion 2017-08-03 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02035787

    Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients

    Not yet reported UNC Lineberger Comprehensive Cancer Center 20 participants Est. completion 2024-04-12 2 sites Stand-alone
    Other conditions: Complex Atypical Hyperplasia, Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT02036515

    Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)

    Not yet reported Merck Sharp & Dohme LLC 464 participants Est. completion 2016-06-06 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02037672

    PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome

    Not yet reported University Medical Centre Ljubljana 36 participants Est. completion 2014-01 1 site
    Other conditions: PCOS, Obesity
    View official trial listing →
  • Completed NCT NCT02039245

    Multiple Dose Pharmacokinetics of Canagliflozin/Metformin 150/1,000 mg Fixed Dose Combination

    Not yet reported Janssen Research & Development, LLC 12 participants Est. completion 2014-03 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT02039258

    Pharmacokinetics of a Fixed Dose Combination of Canagliflozin/Metformin Coadministered With Food

    Not yet reported Janssen Research & Development, LLC 24 participants Est. completion 2014-03 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT02040246

    Comparison of Metformin and Repaglinide Monotherapy in the Treatment of New Onset Type 2 Diabetes Mellitus in China

    Not yet reported RenJi Hospital 107 participants Est. completion 2014-01 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02040376

    Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma

    Not yet reported The Hospital for Sick Children 24 participants Est. completion 2017-12-15 1 site Stand-alone
    Other conditions: Brain Tumor Treated With Cranial or Cranial-Spinal Radiation
    View official trial listing →
  • Withdrawn NCT NCT02042495

    Endometrial Cancer Biomarker Changes Following Exposure to Metformin

    Not yet reported Jewish General Hospital 1 site Stand-alone
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT02042664

    Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese Diabetics

    Not yet reported Assistance Publique Hopitaux De Marseille 44 participants Est. completion 2015-06 1 site
    Other conditions: Obesity, Diabetes
    View official trial listing →
  • Completed NCT NCT02045290

    Insulin Clamp Ancillary Study for Assessment of Insulin Resistance

    Not yet reported Jaeb Center for Health Research 37 participants Est. completion 2016-02-15 1 site Stand-alone
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT02048384

    A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 22 participants Est. completion 2019-09 2 sites Stand-alone
    Other conditions: Metastatic Pancreatic Adenocarcinoma
    View official trial listing →
  • Status unknown NCT NCT02048761

    Locally Delivered 1% Metformin Gel in the Treatment of Intrabony Defects in Chronic Periodontitis

    Not yet reported Government Dental College and Research Institute, Bangalore 65 participants Est. completion 2014-02 1 site
    Other conditions: Intrabony Defects in Chronic Periodontitis
    View official trial listing →
  • Completed NCT NCT02049034

    Lixisenatide-The Effects on Glucose and Lipid Metabolism in Type 2 Diabetes

    Not yet reported University of Surrey 8 participants Est. completion 2016-01 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT02050009

    Metformin Hydrochloride, Carboplatin, and Paclitaxel in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

    Not yet reported Fox Chase Cancer Center Est. completion 2014-10-31 1 site Stand-alone
    Other conditions: Ovarian Papillary Serous Carcinoma, Ovarian Serous Cystadenocarcinoma, Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Primary Peritoneal Cavity Cancer
    View official trial listing →
  • Completed NCT NCT02050074

    The Role of Metformin and Colesevelam in Human GLP-1 Secretion

    Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2014-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02051842

    Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis

    Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 100 participants Est. completion 2020-12 1 site Stand-alone
    MASLDPrediabetes
    View official trial listing →
  • Completed NCT NCT02052011

    Ranolazine and Microvascular Angina by PET in the Emergency Department

    Not yet reported Yale University 31 participants Est. completion 2015-11 1 site Stand-alone
    Other conditions: Microvascular Angina
    View official trial listing →
  • Terminated NCT NCT02053103

    A 6-Week Study To Determine The Safety And Effect Of An Investigational Drug On Adults With Type 2 Diabetes Mellitus Taking Metformin

    Not yet reported Pfizer 13 participants Est. completion 2014-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02053116

    A 6-Week Study To Determine The Safety And Effect Of An Investigational Drug Given With Canagliflozin In Adults With Type 2 Diabetes Mellitus Taking Metformin

    Not yet reported Pfizer 8 participants Est. completion 2014-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02053272

    A Study of GWP42004 as Add on to Metformin in the Treatment of Participants With Type 2 Diabetes

    Not yet reported Jazz Pharmaceuticals 207 participants Est. completion 2016-02 25 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02056600

    BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone.

    Not yet reported LG Life Sciences 24 participants Est. completion 2014-05 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02058147

    Efficacy and Safety of Insulin Glargine/ Lixisenatide Fixed Ratio Combination Compared to Insulin Glargine Alone and Lixisenatide Alone on Top of Metformin in Patients With T2DM

    Not yet reported Sanofi 1170 participants Est. completion 2015-06 273 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02058160

    Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes

    Not yet reported Sanofi 736 participants Est. completion 2015-07 236 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02060383

    Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or Acromegaly

    Not yet reported Novartis Pharmaceuticals 249 participants Est. completion 2018-03-26 43 sites Mixed
    Other conditions: Cushing's Disease, Acromegaly
    View official trial listing →
  • Completed NCT NCT02061969

    ADA Linagliptin in Long Term Care

    Not yet reported Emory University 140 participants Est. completion 2017-04-10 4 sites Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT02063802

    Metformin vs Conjugated Linoleic Acid and an Intervention Program With Healthy Habits in Obese Children

    Not yet reported Laboratorios Silanes S.A. de C.V. 120 participants Est. completion 2014-05 1 site
    Other conditions: Obesity
    View official trial listing →
  • Status unknown NCT NCT02064881

    Efficacy Study of Metformin Glycinate on Postprandial Lipemia

    Not yet reported, Not yet reported Laboratorios Silanes S.A. de C.V. 72 participants Est. completion 2020-08 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02065687

    Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer

    Not yet reported, Not yet reported Gynecologic Oncology Group 469 participants Est. completion 2023-09-13 431 sites Stand-alone
    Other conditions: Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Endometrial Undifferentiated Carcinoma, Recurrent Uterine Corpus Carcinoma, Stage III Uterine Corpus Cancer AJCC v7, Stage IIIA Uterine Corpus Cancer AJCC v7, Stage IIIB Uterine Corpus Cancer AJCC v7, Stage IIIC Uterine Corpus Cancer AJCC v7, Stage IV Uterine Corpus Cancer AJCC v7, Stage IVA Uterine Corpus Cancer AJCC v7, Stage IVB Uterine Corpus Cancer AJCC v7
    View official trial listing →
  • Completed NCT NCT02065752

    A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components

    Not yet reported Janssen Research & Development, LLC 2 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT02069379

    Endogenous Opioid Activity and Affective State in Insulin Resistant Women

    Not yet reported University of Michigan 42 participants Est. completion 2017-09 1 site Stand-alone
    Metabolic syndrome Other conditions: Depression, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT02071368

    A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants

    Not yet reported Janssen Research & Development, LLC 3 participants Est. completion 2014-05 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT02072096

    A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Eli Lilly and Company 192 participants Est. completion 2015-10 34 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02072382

    The Hypotensive Effect of Metformin in Hypertensive Patients.

    Not yet reported Hospital de Clinicas de Porto Alegre 92 participants Est. completion 2015-12 1 site Stand-alone
    Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT02073227

    A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components

    Not yet reported Janssen Research & Development, LLC 52 participants Est. completion 2014-06 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT02076347

    Comparison of Two Pharmacist-led Population Management Approaches to Increase Monitoring of Vitamin B12 and Serum Creatinine Levels for Patients on Metformin

    Not yet reported Ohio State University 489 participants Est. completion 2015-10 1 site
    Type 2 diabetes Other conditions: Vitamin B12 Deficiency, Neuropathy, Anemia
    View official trial listing →
  • Completed NCT NCT02077803

    A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants

    Not yet reported Janssen Research & Development, LLC 47 participants Est. completion 2014-07 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02080377

    A Feasibility Study Looking at the Use of Glibenclamide and metfoRmin Versus stAndard Care in gEstational diabeteS

    Not yet reported University of Edinburgh 23 participants Est. completion 2016-03 5 sites
    Other conditions: Pregnancy, Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT02081118

    Glycaemic Control of Monthly LAPS-Exendin Versus Placebo in Subjects of Type 2 Diabetes

    Not yet reported Hanmi Pharmaceutical Company Limited 209 participants Est. completion 2015-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02083692

    Pilot Study of Metformin in Head and Neck Squamous Cell Cancer and Its Effects on Stromal-epithelial Metabolic Uncoupling

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 50 participants Est. completion 2017-04-06 1 site Stand-alone
    Other conditions: Head and Neck Squamous Cell Cancer
    View official trial listing →
  • Completed NCT NCT02084056

    Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/1000mg) Extended Release in Healthy Subjects.

    Not yet reported Boehringer Ingelheim 74 participants Est. completion 2014-07 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02084082

    Bioequivalence of a FDC Tablet of Linagliptin/Metformin (5mg/1000mg) Extended Release in Healthy Subjects

    Not yet reported Boehringer Ingelheim 68 participants Est. completion 2014-07 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02086526

    Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)

    Not yet reported Mayo Clinic 68 participants Est. completion 2016-11-20 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Active, not recruiting NCT NCT02087826

    Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS

    Not yet reported Massachusetts General Hospital 1017 participants Est. completion 2026-12 1 site
    Type 2 diabetes Other conditions: Genetics, Metabolism
    View official trial listing →
  • Completed NCT NCT02088034

    Intervention to Promote Weight Loss in Latinas At-risk for Diabetes

    Not yet reported Temple University 92 participants Est. completion 2016-02 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02088918

    A Open-label, Single-dose, 2-Sequence, 2-Period, Crossover Study to Assess Safety and Pharmacokinetics of a Nateglinide/Metformin HCl Combined Tablet Compared With a Nateglinide 120 mg Tablet and Metformin HCl 500 mg Tablet Under Fasting Conditions in Healthy Male Subjects

    Not yet reported IlDong Pharmaceutical Co Ltd 40 participants 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT02091336

    Oral Antidiabetic Agents in Pregnancy

    Not yet reported Hospital de Clinicas de Porto Alegre 80 participants Est. completion 2016-12 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT02091362

    A Study of LY2409021 on Blood Pressure and Pulse Rate in Participants With Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 270 participants Est. completion 2015-01 30 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02097342

    Effect of Linagliptin on Insulin Sensitivity and Pancreatic Beta Cell Function in Patients With Type 2 Diabetes Mellitus

    Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2015-01 1 site
    Type 2 diabetes Other conditions: Insulin Sensitivity/Resistance
    View official trial listing →
  • Completed NCT NCT02099110

    Ertugliflozin and Sitagliptin Co-administration Factorial Study (VERTIS FACTORAL, MK-8835-005)

    Not yet reported Merck Sharp & Dohme LLC 1233 participants Est. completion 2016-05-26 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02100475

    A Trial Comparing Sequential Addition of Insulin Aspart Versus Further Dose Increase With Insulin Degludec/Liraglutide in Subjects With Type 2 Diabetes Mellitus, Previously Treated With Insulin Degludec/Liraglutide and Metformin and in Need of Further Intensification

    Not yet reported Novo Nordisk A/S 31 participants Est. completion 2015-04 60 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02102932

    Bioavailability of Empagliflozin/Metformin Fixed Dose Combinations (FDCs) in Healthy Chinese Volunteers

    Not yet reported Boehringer Ingelheim 96 participants Est. completion 2014-08 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02104804

    Evaluate the Efficacy and Safety of Saxagliptin Added to Insulin Monotherapy or to Insulin Combined With Metformin in Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control

    Not yet reported AstraZeneca 953 participants Est. completion 2016-02-26 11 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02106104

    Renal Effects of DPP-4 Inhibitor Linagliptin in Type 2 Diabetes

    Not yet reported Amsterdam UMC, location VUmc 48 participants Est. completion 2016-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02106923

    Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Extended Release (XR) Compared With Single Tablets

    Not yet reported Boehringer Ingelheim 72 participants Est. completion 2014-07 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02109679

    Relative Bioavailability of Multiple Oral Doses of BI 187004 and Metformin After Co-administration Compared to Multiple Oral Doses of BI 187004 Alone and Metformin Alone in Healthy Male Subjects

    Not yet reported Boehringer Ingelheim 16 participants Est. completion 2014-07 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT02111096

    A Study of LY2409021 in Participants With Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 174 participants Est. completion 2015-09 33 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02111967

    Study to Identify Adequate Biomarker to Detect Vitamin B12 Deficiency in Type 2 Diabetic Patients Treated With Metformin

    University Hospital, Basel, Switzerland 50 participants Est. completion 2014-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02113163

    PK Study Comparing Metformin Eicosapentaenoate to a Combined Dose of Metformin Hydrochloride and Ethyl Ester EPA

    Not yet reported Thetis Pharmaceuticals LLC 32 participants Est. completion 2014-07 1 site
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent, Hypertriglyceridemia
    View official trial listing →
  • Terminated NCT NCT02115464

    Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy

    Not yet reported Ontario Clinical Oncology Group (OCOG) 54 participants Est. completion 2020-04-21 7 sites Stand-alone
    Other conditions: Lung Cancer
    View official trial listing →
  • Completed NCT NCT02119819

    A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes

    Not yet reported OPKO Health, Inc. 420 participants Est. completion 2015-10 51 sites Mixed
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02121509

    Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/750mg) Extended Release in Healthy Subjects

    Not yet reported Boehringer Ingelheim 74 participants Est. completion 2014-07 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02122185

    Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

    Not yet reported University of Chicago 111 participants Est. completion 2024-10-08 10 sites Stand-alone
    Other conditions: Brenner Tumor, Malignant Ascites, Malignant Pleural Effusion, Ovarian Clear Cell Cystadenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Mixed Epithelial Carcinoma, Ovarian Serous Cystadenocarcinoma, Ovarian Undifferentiated Adenocarcinoma, Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Primary Peritoneal Cavity Cancer, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Epithelial Cancer, Stage IIIA Ovarian Germ Cell Tumor, Stage IIIA Primary Peritoneal Cavity Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Epithelial Cancer, Stage IIIB Ovarian Germ Cell Tumor, Stage IIIB Primary Peritoneal Cavity Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Epithelial Cancer, Stage IIIC Ovarian Germ Cell Tumor, Stage IIIC Primary Peritoneal Cavity Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Epithelial Cancer, Stage IV Ovarian Germ Cell Tumor, Stage IV Primary Peritoneal Cavity Cancer
    View official trial listing →
  • Completed NCT NCT02125227

    Phase 1 Clinical Trial to Investigate the Effect on the Pharmacokinetics of YH14755 Compared to Co-administration of Rosuvastatin and Metformin SR in Healthy Volunteers

    Not yet reported Yuhan Corporation 56 participants Est. completion 2014-09 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02125305

    Clinical Study to Investigate the Pharmacokinetics and Pharmacodynamics of Metformin in the Elderly

    Not yet reported Seoul National University Hospital 12 participants 1 site Stand-alone
    Other conditions: Healthy Elderly
    View official trial listing →
  • Completed NCT NCT02128932

    Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 1089 participants Est. completion 2015-09-03 231 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT02129985

    Effect on Beta Cell Function and Glycaemic Control After Insulin and Exenatide Sequential Therapy

    Not yet reported xiaolong zhao 100 participants Est. completion 2015-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02131272

    A Trial Investigating the Efficacy and Safety of Insulin Detemir Versus Insulin NPH in Combination With Metformin and Diet/Exercise in Children and Adolescents With Type 2 Diabetes Insufficiently Controlled on Metformin With or Without Other Oral Antidiabetic Drug(s) With or Without Basal Insulin

    Not yet reported Novo Nordisk A/S 42 participants Est. completion 2016-06-14 82 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02133118

    Weight Trajectory in New Users of Sulfonylureas as Add on Therapy Next to Metformin.

    Medical Research Foundation, The Netherlands 16293 participants Est. completion 2014-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02135549

    Study of the Effectiveness and Safety of SugarDown vs. Placebo in Type 2 Diabetic Subjects Treated With Metformin

    Not yet reported Boston Therapeutics 24 participants Est. completion 2014-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02138097

    Oral and Non-insulin Injected Hypoglycemic Therapy Utilization Patterns

    Boehringer Ingelheim 615067 participants Est. completion 2014-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02140788

    Effects of Metformin and Fish Oil on Treatment With Clozapine

    Not yet reported Duke University 34 participants Est. completion 2013-02
    Other conditions: Schizophrenia, Schizo-affective Disorder
    View official trial listing →
  • Status unknown NCT NCT02142309

    Glycemic Durability After Metformin Failure

    Not yet reported University of Campania Luigi Vanvitelli 450 participants Est. completion 2017-01 2 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT02143050

    Study of Dabrafenib, Trametinib and Metformin for Melanoma Patients

    Not yet reported, Not yet reported University of Louisville Est. completion 2017-11-17 2 sites Stand-alone
    Other conditions: Melanoma
    View official trial listing →
  • Completed NCT NCT02145559

    A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors

    Not yet reported University of Chicago 24 participants Est. completion 2018-07 1 site Stand-alone
    Other conditions: Breast Neoplasms, Lung Neoplasms, Cancer of Liver, Lymphoma, Cancer of Kidney
    View official trial listing →
  • Completed NCT NCT02145611

    Vildagliptin vs. Glibenclamide in Endothelial Function in Type 2 Diabetes and Hypertension

    Not yet reported Dr. José Fernando Vilela-Martin MD PhD 50 participants Est. completion 2016-05 1 site
    Type 2 diabetes Other conditions: Hypertension, Endothelial Dysfunction
    View official trial listing →
  • Completed NCT NCT02147925

    Efficacy Study of Liraglutide vs.Sitagliptin vs. Glargine on Liver Fat in T2DM Subjects

    Not yet reported Sun Yat-sen University 75 participants Est. completion 2017-04 1 site
    Other conditions: Non-alcoholic Fatty Liver Disease
    View official trial listing →
  • Status unknown NCT NCT02149459

    Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy

    Not yet reported Sheba Medical Center 18 participants Est. completion 2018-07 1 site Stand-alone
    Other conditions: Brain Neoplasms
    View official trial listing →
  • Completed NCT NCT02150824

    Safety and Tolerability, Efficacy, Pharmacokinetic and Pharmacodynamic Study of Three Doses of BI 187004 Over 28 Days in Patients With Type 2 Diabetes Mellitus With and Without Metformin

    Not yet reported Boehringer Ingelheim 103 participants Est. completion 2015-08 3 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02151461

    Dose Comparisons of Leucine-Metformin Combinations on Blood Glucose Levels In Type 2 Diabetic Patients

    Not yet reported NuSirt Biopharma 96 participants Est. completion 2016-01 9 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02152371

    A Study of Dulaglutide (LY2189265) in Participants With Type II Diabetes

    Not yet reported Eli Lilly and Company 300 participants Est. completion 2015-10 40 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02153450

    Stereotactic Radiosurgery and Metformin in Patients With Borderline-Resectable or Locally-Advanced Pancreatic Cancer

    Not yet reported Case Comprehensive Cancer Center 8 participants Est. completion 2020-06-13 1 site Stand-alone
    Other conditions: Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage I-III Pancreatic Cancer
    View official trial listing →
  • Completed NCT NCT02157974

    Liver and Fat Regulation in Overweight Adolescent Girls

    Not yet reported, Not yet reported University of Colorado, Denver 92 participants Est. completion 2022-12 1 site
    Other conditions: Hepatic Steatosis, Polycystic Ovarian Syndrome, Obesity
    View official trial listing →
  • Completed NCT NCT02160743

    The Food Effect on Pharmacokinetics and Safety of Fixed-dose Combination of CJ-30056 in Healthy Male Subjects

    Not yet reported HK inno.N Corporation 28 participants Est. completion 2014-11 1 site Stand-alone
    Other conditions: Food Effect Study of CJ-30056 20mg/500mg
    View official trial listing →
  • Completed NCT NCT02167061

    A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01 Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg, and to Evaluate the Effect of Food on the Pharmacokinetics of DA-1229_01 in Healthy Male Volunteers

    Not yet reported Dong-A ST Co., Ltd. 64 participants Est. completion 2014-11 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02172248

    Relative Bioavailability BI 10773 and Metformin in Healthy Male Volunteers

    Not yet reported Boehringer Ingelheim 16 participants Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02173639

    Bioavailability of Combination Tablet BI 1356/Metformin Compared With Single BI 1356 and Metformin Administered Together to Healthy Male and Female Subjects

    Not yet reported Boehringer Ingelheim 20 participants Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02176161

    Metformin Prostate Cancer Adjuvant Trial

    Not yet reported NYU Langone Health 59 participants Est. completion 2021-07-21 1 site Stand-alone
    Other conditions: Prostate Cancer, Prostate Cancer Recurrent
    View official trial listing →
  • Completed NCT NCT02179788

    Metformin to Augment Low Milk Supply (MALMS) Study

    Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 15 participants Est. completion 2016-07 1 site Stand-alone
    Prediabetes Other conditions: Low Milk Supply, Insulin Resistance, Suppressed Lactation
    View official trial listing →
  • Completed NCT NCT02183506

    Bioavailability of BI 1356 BS and Metformin After Co-administration Compared to the Bioavailability of BI 1356 BS Alone and Metformin Alone in Healthy Male Volunteers

    Not yet reported Boehringer Ingelheim 16 participants Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02183571

    Bioequivalence Study of Two Strengths of Two Different Metformin Tablets Administered to Healthy Male and Female Subjects

    Not yet reported Boehringer Ingelheim 56 participants Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02183935

    Treatment of Morbidly Obese Adolescent With a Duodena-jejunal Liner

    Not yet reported University Medical Centre Ljubljana 22 participants Est. completion 2018-12-20 1 site
    Metabolic syndrome Other conditions: Obesity, Diabetes
    View official trial listing →
  • Completed NCT NCT02184832

    Dietary Intake of Tryptophan and Metformin Response

    Not yet reported Massachusetts General Hospital 20 participants Est. completion 2016-03 1 site Stand-alone
    Other conditions: Metformin Response, Fasting Glucose, Tryptophan Concentration, Metformin Concentration, Diet Tolerability
    View official trial listing →
  • Completed NCT NCT02186483

    Clinical Trial to Investigate the Pharmacokinetics Drug Interaction Between Metformin and Rosuvastatin

    Not yet reported Jeil Pharmaceutical Co., Ltd. 24 participants Est. completion 2015-02 1 site Stand-alone
    Other conditions: Hyperlipidemia, Diabetes
    View official trial listing →
  • Completed NCT NCT02186847

    Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

    Not yet reported NRG Oncology 170 participants Est. completion 2025-09-04 223 sites Stand-alone
    Other conditions: Adenosquamous Lung Carcinoma, Bronchioloalveolar Carcinoma, Large Cell Lung Carcinoma, Lung Adenocarcinoma, Non-Small Cell Lung Carcinoma, Recurrent Non-Small Cell Lung Carcinoma, Squamous Cell Lung Carcinoma, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT02187250

    PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary Syndrome

    Not yet reported University Medical Centre Ljubljana 45 participants Est. completion 2014-06 1 site
    Other conditions: PCOS, Obesity
    View official trial listing →
  • Completed NCT NCT02188186

    Therapeutic Efficacy of Triple Combination in Drug-naïve Korean Type 2 Diabetic Patients

    Not yet reported Seoul National University Bundang Hospital 200 participants Est. completion 2018-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02188654

    Metformin in Psoriatic Arthritis

    Not yet reported University of Alexandria 56 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: Psoriatic Arthritis
    View official trial listing →
  • Terminated NCT NCT02190838

    Comparison of Melatonin or Metformin and Dacarbazine Combination Versus Dacarbazine Alone in Disseminated Melanoma

    Not yet reported N.N. Petrov National Medical Research Center of Oncology 57 participants Est. completion 2018-12-31 3 sites Stand-alone
    Other conditions: Melanoma
    View official trial listing →
  • Completed NCT NCT02192424

    Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Main Trial)

    Not yet reported Mount Sinai Hospital, Canada 109 participants Est. completion 2020-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02198417

    Metformin Treatment in Polycystic Ovary Syndrome (PCOS)

    Not yet reported Massachusetts General Hospital 20 participants Est. completion 2020-12 Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Withdrawn NCT NCT02201381

    Study of the Safety, Tolerability and Efficacy of Metabolic Combination Treatments on Cancer

    Not yet reported Health Clinics Limited Est. completion 2027-09-23 1 site Stand-alone
    Other conditions: Cancer, Overall Survival
    View official trial listing →
  • Completed NCT NCT02202161

    A Study Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 Administered With Metformin to Type 2 Diabetes Patients

    Not yet reported GlaxoSmithKline 70 participants Est. completion 2015-01-30 4 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02205528

    A Study of Once-Daily NNC0090-2746 in Participants With Type 2 Diabetes Inadequately Controlled With Metformin

    Not yet reported Novo Nordisk A/S 108 participants Est. completion 2015-09-15 20 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02206607

    Study To Compare Single Dose Of Three Modified Release Formulations Of PF-04937319 With Immediate Release Material-Sparing-Tablet (IR MST) Formulation Previously Studied In Adults With Type 2 Diabetes Mellitus.

    Not yet reported Pfizer 39 participants Est. completion 2015-01 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02212756

    Pharmacokinetic Profiles of Metformin With DW1029M

    Not yet reported Dong Wha Pharmaceutical Co. Ltd. 12 participants Est. completion 2015-02 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Withdrawn NCT NCT02217670

    Comparative Bioavailability Study of Metformin HCl 1000 mg Granules vs Glucophage 1000 mg Film-coated Tablet

    Not yet reported Disphar International B.V. 1 site Stand-alone
    Other conditions: Comparative Bioavailability
    View official trial listing →
  • Completed NCT NCT02219750

    Comparison of Premixed Insulin With Basal-plus Insulin in Type 2 Diabetes Patients

    Not yet reported Mackay Memorial Hospital 181 participants Est. completion 2016-08 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02220218

    Bioequivalence Study of Metformin Component of Canagliflozin and Metformin Fixed Dose Combination Immediate Release (IR) Tablet Comparing With Metformin IR Tablet Co-administered With Canagliflozin Tablet in Healthy Fed and Fasted Participants

    Not yet reported Janssen Research & Development, LLC 2 participants Est. completion 2014-10 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02220647

    Bioequivalence of a 2.5 mg Linagliptin / 850 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 850 mg Tablets in Healthy Volunteers

    Not yet reported Boehringer Ingelheim 96 participants Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02221180

    Bioequivalence Study of Metformin Component of Fixed Dose Combination (FDC) Immediate Release (IR) Tablet of Canagliflozin and Metformin Compared to Metformin IR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants

    Not yet reported Janssen Research & Development, LLC 2 participants Est. completion 2014-11 1 site Stand-alone
    Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT02221401

    Bioequivalence of a Linagliptin / Metformin Fixed-dose Combination (FDC) Tablet Compared With Single Linagliptin and Metformin Tablets Administered Together in Healthy Volunteers

    Not yet reported Boehringer Ingelheim 96 participants Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02221414

    Bioequivalence of a 2.5 mg Linagliptin / 500 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 500 mg Tablets Administered Together in Healthy Volunteers

    Not yet reported Boehringer Ingelheim 95 participants Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02223026

    Relative Bioavailability of a Linagliptin+Metformin Fixed Dose Combination Tablet Administered With and Without Food to Healthy Male and Female Subjects

    Not yet reported Boehringer Ingelheim 32 participants
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02226510

    MetfoRmin and Its Effects on Left Ventricular Hypertrophy in Normotensive Patients With Coronary Artery Disease

    Not yet reported University of Dundee 68 participants Est. completion 2017-12 1 site
    Cardiovascular diseasePrediabetes Other conditions: Left Ventricular Hypertrophy, Insulin Resistance
    View official trial listing →
  • Withdrawn NCT NCT02229240

    Albiglutide Versus Placebo Added-on to Basal-Bolus Insulin Therapy in Subjects With Type 2 Diabetes Mellitus

    Not yet reported GlaxoSmithKline Est. completion 2015-12 Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02229383

    Phase III Study to Evaluate Safety and Efficacy of Added Exenatide Versus Placebo to Titrated Basal Insulin Glargine in Inadequately Controlled Patients With Type II Diabetes Mellitus

    Not yet reported AstraZeneca 464 participants Est. completion 2016-08-29 123 sites Added to GLP-1
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02229396

    Phase 3 28-Week Study With 24-Week and 52-week Extension Phases to Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo

    Not yet reported AstraZeneca 695 participants Est. completion 2017-12-28 133 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02230995

    Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Subjects

    Not yet reported Boehringer Ingelheim 30 participants Est. completion 2014-10 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02231021

    The Practical Evidence of Antidiabetic Combination Therapy in Korea

    Not yet reported Kun-Ho Yoon 216 participants Est. completion 2019-01-28 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02231931

    Drug-drug Interaction Between Digoxin, Furosemide, Metformin, and Rosuvastatin

    Not yet reported Boehringer Ingelheim 24 participants Est. completion 2015-01-01 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02234440

    Effect of Metformin on Disease Progression in Patients With Cryptogenic Cirrhosis (NASH-related Cirrhosis) With Diabetes or Impaired Glucose Tolerance or Insulin Resistance

    Not yet reported Institute of Liver and Biliary Sciences, India 86 participants Est. completion 2015-12-31 1 site Stand-alone
    MASH
    View official trial listing →
  • Completed NCT NCT02235298

    Dapagliflozin Effects on Epicardial Fat

    Not yet reported University of Miami 100 participants Est. completion 2020-09-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02243176

    24-Week, Multicenter, Randomized, Parallel-group, Open-label, Active Controlled Phase IV Study to Assess the Efficacy, Safety and Tolerability of Saxagliptin Compared With Acarbose When in Combination With Metformin in Patients With T2D Inadequately Controlled With Metformin Monotherapy

    Not yet reported AstraZeneca 689 participants Est. completion 2015-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02244164

    Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments.

    Not yet reported Erasme University Hospital 5 participants Est. completion 2023-02-13 1 site
    Type 2 diabetes Other conditions: Incretinomimetics, Pancreas
    View official trial listing →
  • Status unknown NCT NCT02244567

    Effect of Metformin Therapy on Serum Under-carboxylated Osteocalcin Levels in Hyperandrogenic Lean Polycystic Ovarian Syndrome Women

    Not yet reported Beni-Suef University 100 participants Est. completion 2021-06 1 site
    Other conditions: Polycystic Ovarian Syndrome
    View official trial listing →
  • Status unknown NCT NCT02246257

    Early Rheumatoid Arthritis COR Intervention

    Not yet reported MD, PhD, Annemarie Lyng Svensson 300 participants Est. completion 2024-09 1 site
    Cardiovascular disease Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Completed NCT NCT02249910

    Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Metformin and Digoxin in Healthy Subjects

    Not yet reported Novo Nordisk A/S 32 participants Est. completion 2015-03-06 1 site Added to GLP-1
    Other conditions: Diabetes, Healthy
    View official trial listing →
  • Withdrawn NCT NCT02250794

    Metformin and Sitagliptin Therapy for Adult Patients With Type 2 Diabetes Admitted to the General Medical Unit

    Not yet reported Rush University Medical Center Est. completion 2015-05 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02252081

    Metformin in Kidney Disease

    Not yet reported VA Office of Research and Development 125 participants Est. completion 2019-12-31 1 site
    Chronic kidney diseaseCardiovascular diseaseMetabolic syndrome
    View official trial listing →
  • Completed NCT NCT02252965

    Metformin Extended Release Versus Metformin Immediate Release in Subjects With Type 2 Diabetes

    Not yet reported Merck KGaA, Darmstadt, Germany 532 participants Est. completion 2016-04 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02266472

    Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Male and Female

    Not yet reported Boehringer Ingelheim 30 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02269098

    The Synergy to Control Emergency Department Hyperglycemia Program for Type 2 Diabetes

    Not yet reported Medstar Health Research Institute 101 participants Est. completion 2013-12 1 site Stand-alone
    Type 2 diabetes Other conditions: Medication Adherence, HYPERGLYCEMIA
    View official trial listing →
  • Completed NCT NCT02272556

    Investigating the Role of the Polyol Pathway in the Central Nervous System

    Not yet reported Yale University 138 participants Est. completion 2022-05-18 1 site
    Other conditions: Hyperglycemia
    View official trial listing →
  • Completed NCT NCT02273050

    Evaluate the Efficacy and Safety of Saxagliptin in Combination With Metformin IR Compared to Saxagliptin Monotherapy and to Metformin IR Monotherapy in Drug Naive Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control

    Not yet reported AstraZeneca 1136 participants Est. completion 2016-08 17 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02274090

    1% Metformin in Moderate and Severe Periodontitis

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 70 participants Est. completion 2014-08
    Other conditions: Periodontitis
    View official trial listing →
  • Terminated NCT NCT02274740

    Effect of Lixisenatide on Postprandial Lipid Profile in Obese Type 2 Diabetic Patients

    Not yet reported Sanofi 2 participants Est. completion 2015-08 Added to GLP-1
    Other conditions: Type II Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02274948

    Use of Metformin in Treatment of Childhood Obesity

    Not yet reported University of Colombo 339 participants Est. completion 2016-04 1 site
    Other conditions: Pediatric Obesity
    View official trial listing →
  • Status unknown NCT NCT02275845

    Medico-GDM Trial - Metformine to Prevent Gestational Diabetes Mellitus

    Not yet reported Maasstad Hospital 400 participants Est. completion 2017-09 1 site Stand-alone
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02276274

    Effect of Food on the Pharmacokinetics of Single Oral Dose Administration of a Fixed-Dose Combination of SYR-322 and Metformin Hydrochloride in Healthy Adult Male Subjects

    Not yet reported Takeda 12 participants Est. completion 2014-06 1 site
    Other conditions: Clinical Pharmacology
    View official trial listing →
  • Completed NCT NCT02278965

    Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer

    Not yet reported Katherine D. Crew 19 participants Est. completion 2017-04-19 1 site Stand-alone
    Other conditions: Stage 0 Breast Carcinoma, Breast Neoplasms, Stage I Breast Carcinoma, Stage II Breast Carcinoma, Stage III Breast Carcinoma
    View official trial listing →
  • Status unknown NCT NCT02279758

    A Pilot Study of Metformin Treatment in Patients With Well-differentiated Neuroendocrine Tumors

    Not yet reported Instituto do Cancer do Estado de São Paulo 30 participants 1 site
    Other conditions: Well-differentiated Neuroendocrine Tumors
    View official trial listing →
  • Completed NCT NCT02280057

    Trial With Metformin in Women With Polycystic Ovary Syndrome

    Not yet reported Herning Hospital 56 participants Est. completion 2002-12 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02280486

    Efficacy and Safety of Saxagliptin VS. Glimepiride in Chinese T2DM Patients Controlled Inadequately With Metformin

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 388 participants Est. completion 2017-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02282423

    PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes

    Not yet reported Mayo Clinic 26 participants Est. completion 2016-04 1 site Stand-alone
    Other conditions: Diabetes, Obesity
    View official trial listing →
  • Completed NCT NCT02283554

    Platelet Rich Fibrin With 1% Metformin Gel for Treatment of Intrabony Defects

    Not yet reported Government Dental College and Research Institute, Bangalore 120 participants Stand-alone
    Other conditions: Periodontitis
    View official trial listing →
  • Completed NCT NCT02284893

    Study to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin in Combination With Metformin Compared to Sitagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Therapy Alone

    Not yet reported AstraZeneca 461 participants Est. completion 2016-09-20 79 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02285855

    Metformin in Non Small Cell Lung Cancer (NSCLC)

    Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2019-01-05 1 site Stand-alone
    Other conditions: Lung Cancer
    View official trial listing →
  • Completed NCT NCT02286128

    Effect of NF-кB Dependent Proinflammation on Osteogenic Differentiation of the Mesenchymal Stem Cells in Type 2 Diabetes

    Chiang Mai University 75 participants Est. completion 2018-05-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02288273

    Study to Evaluate the Effect of BYDUREON on 24-hour Glucose Control in Metformin Treated Patients With Type 2 Diabetes.

    Not yet reported AstraZeneca 239 participants Est. completion 2015-08 29 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02290184

    PilAm Go4Health Weight Loss Program to Prevent Heart Disease

    Not yet reported University of California, San Francisco 45 participants Est. completion 2017-08 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02291510

    Assessing the PK of Met DR, Met IR, and Met XR in Healthy Subjects

    Not yet reported Elcelyx Therapeutics, Inc. 20 participants Est. completion 2012-12 Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT02292290

    Trial for People With Established Type 2 Diabetes During Ramadan

    Not yet reported University of Leicester 99 participants Est. completion 2012-12 2 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02294006

    Activity and Safety of Everolimus+Octreotide LAR+Metformin in Advanced Pancreatic Well-differentiated NETs

    Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 26 participants Est. completion 2021-10 1 site Stand-alone
    Other conditions: Well Differentiated Pancreatic Endocrine Tumor
    View official trial listing →
  • Completed NCT NCT02298192

    A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration Algorithms

    Not yet reported Novo Nordisk A/S 420 participants Est. completion 2015-12-23 84 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT02303405

    Hydroxychloroquine Versus Pioglitazone in Combination Treatment for Type 2 Diabetes Mellitus

    Not yet reported Charles Drew University of Medicine and Science 22 participants Est. completion 2017-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02304081

    Saxagliptin in Combination With Dapagliflozin - Effects on Islet Cell Function

    Not yet reported Prof. Dr. Thomas Forst 64 participants Est. completion 2016-08 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02304536

    Comparison Between Laparoscopic Ovarian Diathermy and Urinary Purified FSH in Women With Clomiphene Citrate Resistant Polycystic Ovarian Syndrome.

    Not yet reported Cairo University 210 participants 2 sites
    Other conditions: Infertility
    View official trial listing →
  • Completed NCT NCT02305381

    Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to Basal Insulin Alone or Basal Insulin in Combination With Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 397 participants Est. completion 2015-11-21 99 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Withdrawn NCT NCT02306070

    Improving Fibrosis Outcomes With Metformin

    Not yet reported Ottawa Hospital Research Institute Est. completion 2018-04-03 1 site Stand-alone
    Other conditions: HIV Infection, Hepatitis C
    View official trial listing →
  • Completed NCT NCT02308228

    Metformin to Augment Strength Training Effective Response in Seniors (MASTERS)

    Not yet reported Philip Kern 109 participants Est. completion 2018-06-28 2 sites Stand-alone
    Other conditions: Aging
    View official trial listing →
  • Status unknown NCT NCT02315287

    Comparison of Lobeglitazone With Pioglitazone as Initial Triple Therapy for Diabetes Management

    Not yet reported Seoul National University Bundang Hospital 190 participants Est. completion 2021-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02319200

    Primary Prevention Hepatocellular Carcinoma by Metformin

    Not yet reported Assistance Publique - Hôpitaux de Paris 11 participants Est. completion 2016-04 1 site Stand-alone
    Other conditions: Hepatocellular Carcinoma, Hepatitis C, Chronic, Cirrhosis
    View official trial listing →
  • Status unknown NCT NCT02325245

    Effects of Metformin in Pre-frail Elderly

    Not yet reported Universitas Indonesia 150 participants Est. completion 2017-03 1 site Stand-alone
    Other conditions: Pre-frail Elderly
    View official trial listing →
  • Completed NCT NCT02325401

    Dose-finding Study of Metformin With Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma

    Not yet reported University of Cincinnati 20 participants Est. completion 2020-02-21 1 site Stand-alone
    Other conditions: Head and Neck Cancer
    View official trial listing →
  • Completed NCT NCT02325960

    A Comparison of Exenatide and Insulin Glargine

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 44 participants Est. completion 2016-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT02336087

    Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery

    Not yet reported City of Hope Medical Center 21 participants Est. completion 2026-12-09 4 sites Stand-alone
    Other conditions: Pancreatic Adenocarcinoma, Unresectable Pancreatic Carcinoma, Stage III Pancreatic Cancer AJCC v6 and v7, Stage IV Pancreatic Cancer AJCC v6 and v7
    View official trial listing →
  • Completed NCT NCT02338193

    Dapagliflozin and Metformin,Alone and in Combination, in Overweight/Obese Prior GDM Women

    Not yet reported Woman's 69 participants Est. completion 2019-03-13 1 site Stand-alone
    Other conditions: Diabetes Prevention in Women After GDM Who Are at High-risk
    View official trial listing →
  • Completed NCT NCT02338921

    Triple Combination Therapy in Type 2 Diabetic Patients Who Had Inadequate Glycemic Control With Combination Therapy

    Not yet reported Seoul National University Bundang Hospital 78 participants Est. completion 2021-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02339168

    Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer

    Not yet reported University of California, Davis 25 participants Est. completion 2025-02-24 1 site Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT02341703

    Ovulation Induction in Clomiphene Citrate Resistant PCO Women

    Not yet reported Cairo University 100 participants Est. completion 2015-07 1 site
    Other conditions: Polycystic Ovary Syndrome, Infertility
    View official trial listing →
  • Completed NCT NCT02342925

    A Study of the Effect of RG1662 on Metformin in Healthy Volunteers

    Not yet reported Hoffmann-La Roche 17 participants Est. completion 2015-05 1 site Stand-alone
    Other conditions: Healthy Volunteer
    View official trial listing →
  • Completed NCT NCT02343926

    Phase 3 Study to Compare the Efficacy and Safety of Gemigliptin and Vildagliptin as Add-on Therapy to Metformin in People With Type 2 Diabetes Inadequately Controlled With Metformin

    Not yet reported Sanofi 443 participants Est. completion 2016-04 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02354027

    The Drug-drug Interaction of SHR3824 and Metformin

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 12 participants Est. completion 2015-01 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02355145

    Non-inteRvEntional Study to Observe rAtionaLe to Select add-on TherapY for Type 2 Diabetes Inadequately Controlled With Metformin.

    AstraZeneca 1005 participants Est. completion 2016-07-28 3 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02360618

    Metformin and Simvastatin Use in Bladder Cancer

    Not yet reported London Health Sciences Centre 44 participants Est. completion 2018-01 1 site Stand-alone
    Other conditions: Bladder Cancer
    View official trial listing →
  • Terminated NCT NCT02365233

    Fatty Liver Study in Patients With Type II Diabetes

    Not yet reported The University of Texas Medical Branch, Galveston 5 participants Est. completion 2016-12-31 1 site
    Other conditions: Type II Diabetes, Nonalcoholic Fatty Liver
    View official trial listing →
  • Status unknown NCT NCT02366377

    The PK/PD, Efficacy, Safety and Tolerability Study of SHR3824 in Combination With Metformin in Type 2 Diabetes Mellitus Patients

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 168 participants Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02367066

    A Phase I Study to Assess the Pharmacodynamics of Oral AR-C165395XX in Subjects With Type 2 Diabetes Mellitus (T2DM)

    Not yet reported AstraZeneca 30 participants Est. completion 2015-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02368704

    Role of Endoplasmic Reticulum Stress in the Pathophysiology of Type 2 Diabetes

    Assistance Publique - Hôpitaux de Paris 40 participants Est. completion 2016-11 1 site
    Type 2 diabetes Other conditions: Endoplasmic Reticulum Stress
    View official trial listing →
  • Completed NCT NCT02372656

    Simvastatin and Metformin in Chronic Periodontitis

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 98 participants Est. completion 2014-08
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Terminated NCT NCT02373865

    Risk of Nocturnal Hypoglycemia and Arrhythmias With Sitagliptin Versus Glimepiride in Patients With Type 2 Diabetes

    Not yet reported GWT-TUD GmbH 4 participants Est. completion 2017-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02375139

    A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01(Evogliptin/Metformin XR 2.5/500 mg x 2 Tablets) Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg in Healthy Male Volunteers

    Not yet reported Dong-A ST Co., Ltd. 36 participants Est. completion 2015-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02376166

    Metformin for Rising PSA Remote Trial

    Not yet reported Matthew Galsky 15 participants Est. completion 2016-12 1 site Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT02378441

    Phase 1 Study to Compare the Safety, Pharmacokinetic Profiles of CJ-30056 and Lipitor 20mg/Glucophage SR 750mg

    Not yet reported HK inno.N Corporation 42 participants Est. completion 2015-08 Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02383563

    Metformin for HIV Inflammation

    Not yet reported University of Hawaii 12 participants Est. completion 2016-02 1 site
    Cardiovascular disease Other conditions: HIV
    View official trial listing →
  • Completed NCT NCT02384109

    A Pharmacist-Coordinated Implementation of the Diabetes Prevention Program

    Not yet reported University of California, Los Angeles 521 participants Est. completion 2019-06 20 sites Stand-alone
    Other conditions: Prediabetic State
    View official trial listing →
  • Terminated NCT NCT02393573

    Attenuating The Post-Operative Insulin Resistance And Promoting Protein Anabolism

    Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 7 participants Est. completion 2018-03 1 site
    Prediabetes Other conditions: Major Lung or Abdominal Surgery, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT02394158

    Preventing Recurrent Gestational Diabetes With Metformin

    Not yet reported Imperial College London 112 participants Est. completion 2019-09-30 2 sites
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02394652

    The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized Trial

    Not yet reported University Health Network, Toronto 16 participants Est. completion 2021-01-12 5 sites Stand-alone
    Other conditions: Uterine Cervical Neoplasms, Squamous Cell Carcinoma, Adenocarcinoma, Carcinoma, Adenosquamous
    View official trial listing →
  • Withdrawn NCT NCT02395237

    COMPOUND (INN): HOE490O - GLIMEPIRIDE / METFORMIN HCl (Amaryl® M)0 (Glimepiride/Metformin Hydrochloride Immediate Release Combination Tablet) in Fed Conditions in Healthy Male and/or Female Subjects.

    Not yet reported Pharmaceutical Research Unit, Jordan Est. completion 2015-12 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02401880

    Effects of Linagliptin in Addition to Empagliflozin on Islet Cell Physiology

    Not yet reported Profil Institut für Stoffwechselforschung GmbH 89 participants Est. completion 2015-12 2 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02402348

    Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis

    Not yet reported West Virginia University 3 participants Est. completion 2016-08 1 site Stand-alone
    Other conditions: Cancer of Head and Neck
    View official trial listing →
  • Completed NCT NCT02405260

    Add Glucokinase Activator to Target A1c

    Not yet reported vTv Therapeutics 190 participants Est. completion 2016-09 20 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02407899

    Protective Effects of Saxagliptin (And Vitamin D3) on β Cell Function in Adult-onset Latent Autoimmune Diabetes

    Not yet reported Second Xiangya Hospital of Central South University 300 participants Est. completion 2020-12-31 39 sites Stand-alone
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Terminated NCT NCT02409238

    Insulin Resistance and Mild Cognitive Impairment (IRMCI) Study

    Not yet reported SingHealth Polyclinics 105 participants Est. completion 2019-12-31 1 site Stand-alone
    Type 2 diabetes Other conditions: Mild Cognitive Impairment, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT02411825

    Multiple Ascending Dose Study in Healthy Male Subjects and Overweight to Obese Male and Female Type 2 Diabetes Mellitus (T2DM) Patients

    Not yet reported Sanofi 76 participants Est. completion 2016-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02417090

    Late Metabolic Effects of Metformin Therapy in Gestational Diabetes

    Turku University Hospital 173 participants Est. completion 2019-12-01
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT02419612

    A 52-week International, Multicenter Trial With a Long -Term Extension to Evaluate Saxagliptin With Dapagliflozin in Combination With Metformin Compared to Glimepiride in Combination With Metformin in Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone

    Not yet reported AstraZeneca 444 participants Est. completion 2019-09-18 84 sites
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02420262

    A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Novo Nordisk A/S 506 participants Est. completion 2016-10-05 117 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02420392

    Effects of Dapagliflozin on the Incretin Sensitivity of the Pancreatic Beta Cell

    Not yet reported Seoul National University Hospital 30 participants Est. completion 2016-04 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02420652

    Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy

    Not yet reported Rutgers, The State University of New Jersey 27 participants Est. completion 2019-12-01 1 site Stand-alone
    Other conditions: Recurrent Prostate Carcinoma, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer, Stage III Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT02426294

    Comparison of Pioglitazone Versus Glimepiride in Type 2 Diabetes Inadequately Controlled With Metformin Plus Alogliptin

    Not yet reported Pusan National University Hospital 154 participants Est. completion 2016-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02429258

    Effect of Dapagliflozin on 24-hour Blood Glucose in T2DM Patients Inadequately Controlled With Either Metformin Or Insulin

    Not yet reported AstraZeneca 226 participants Est. completion 2015-10 26 sites Stand-alone
    Other conditions: Type II Diabetes
    View official trial listing →
  • Completed NCT NCT02430870

    TAK-648 Multiple-Rising Dose Study in Healthy Japanese Participants and Non-Japanese Participants With Type 2 Diabetes Mellitus

    Not yet reported Takeda 48 participants Est. completion 2015-11 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02431676

    Survivorship Promotion In Reducing IGF-1 Trial

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 121 participants Est. completion 2018-12 1 site Stand-alone
    Other conditions: Breast Cancer, Prostate Cancer, Lung Cancer, Colon Cancer, Melanoma of Skin, Endometrial Cancer, Liver Cancer, Pancreatic Cancer, Rectal Cancer, Kidney Cancer, Other Solid Malignant Tumors
    View official trial listing →
  • Completed NCT NCT02432287

    Metformin in Longevity Study (MILES).

    Not yet reported Albert Einstein College of Medicine 16 participants Est. completion 2017-12 1 site Stand-alone
    Other conditions: Aging
    View official trial listing →
  • Completed NCT NCT02434744

    Study of KD026 in Combination With Metformin in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Response Pharmaceuticals 121 participants Est. completion 2016-03 10 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02435277

    An Extension Protocol to Evaluate Dose Comparisons of Leucine-Metformin Combinations in Type 2 Diabetic Patients

    Not yet reported NuSirt Biopharma 50 participants Est. completion 2016-01 9 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02437656

    Combination of Metformin to Neoadjuvant Radiochemotherapy in the Treatment of Locally Advanced Rectal Cancer.

    Not yet reported Centre Oscar Lambret 60 participants Est. completion 2017-03 11 sites Stand-alone
    Other conditions: Rectal Cancer
    View official trial listing →
  • Status unknown NCT NCT02437812

    Study of Paclitaxel, Carboplatin and Oral Metformin in the Treatment of Advanced Stage Ovarian Carcinoma

    Not yet reported Gynecologic Oncology Associates 30 participants Est. completion 2021-04 1 site Stand-alone
    Other conditions: Epithelial Ovarian Carcinoma
    View official trial listing →
  • Status unknown NCT NCT02438020

    Study of Efficacy of Metformin in the Treatment of Acanthosis Nigricans in Children With Obesity

    Not yet reported Juan Pablo Castanedo-Cazares 30 participants Est. completion 2016-10 1 site Stand-alone
    Other conditions: Acanthosis Nigricans
    View official trial listing →
  • Status unknown NCT NCT02438397

    the Efficacy of Acarbose and Metformin on Blood Glucose Fluctuation When Combined With Premix Insulin

    Not yet reported Shanghai 6th People's Hospital 80 participants Est. completion 2016-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02438540

    Comparative the Effect of Metformin and Acupuncture on Weight Loss and Insulin Sensitivity

    Not yet reported Amir Firouzjaei 43 participants Est. completion 2015-04 Stand-alone
    Other conditions: Insulin Sensitivity, Obesity
    View official trial listing →
  • Completed NCT NCT02440893

    Understanding the Effect of Metformin on Corus CAD (or ASGES)

    CardioDx 37 participants Est. completion 2014-06
    Cardiovascular disease Other conditions: Angina Pectoris, Chest Pain, Coronary Heart Disease, CAD, CVD, CHD
    View official trial listing →
  • Status unknown NCT NCT02443922

    Dynamic Responsiveness of Insulin Secretory Parameters To Sitagliptin and Glimeperide Administration in Type 2 DM

    Not yet reported Foundation for the National Institutes of Health 100 participants Est. completion 2015-12 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02446834

    Research of Intensive Lifestyle Intervention for PCOS Patients With IGT

    Not yet reported RenJi Hospital 40 participants Est. completion 2018-04 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02449187

    Investigate the Effect of Food on the Pharmacokinetics of JLP-1310 in Healthy Male Volunteers

    Not yet reported Jeil Pharmaceutical Co., Ltd. 16 participants Est. completion 2018-03-09 1 site
    Other conditions: Diabetes, Hyperlipidemia
    View official trial listing →
  • Completed NCT NCT02452632

    A Study to Assess the Efficacy and Safety of ASP1941 in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin

    Not yet reported Astellas Pharma Korea, Inc. 143 participants Est. completion 2017-01-05 22 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02453685

    A Study to Compare Insulin Intensification of Biphasic Insulin Aspart 30 and Insulin Analogues (Insulin Glargine and Insulin Aspart) in Insulin naïve Type 2 Diabetic Patients

    Not yet reported Novo Nordisk A/S 335 participants Est. completion 2016-09-20 41 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02456428

    Incretin-based Drugs and the Risk of Heart Failure

    Canadian Network for Observational Drug Effect Studies, CNODES 1499650 participants Est. completion 2015-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT02457286

    Improving Insulin Resistance To Treat Non-Alcoholic Fatty Liver Disease: A Pilot Study

    Not yet reported Northwell Health Est. completion 2017-07 1 site Stand-alone
    MASLD
    View official trial listing →
  • Terminated NCT NCT02460354

    Metformin and Congenital Nephrogenic Diabetes Insipidus

    Not yet reported Emory University 2 participants Est. completion 2017-06 3 sites Stand-alone
    Other conditions: Diabetes Insipidus
    View official trial listing →
  • Completed NCT NCT02461667

    Alendronate Compared to Metformin in Chronic Periodontitis

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 108 participants Est. completion 2015-03
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Status unknown NCT NCT02462369

    Saxagliptin's Effects on Microalbuminuria Improvement in Type 2 Diabetic Patients

    Not yet reported The Second Hospital of Nanjing Medical University 88 participants Est. completion 2017-10
    Other conditions: Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR
    View official trial listing →
  • Completed NCT NCT02463357

    Three New Ideas to Protect Special Forces From the Stress of High Altitude

    Not yet reported University of Colorado, Denver 148 participants Est. completion 2016-09 1 site Stand-alone
    Other conditions: Mountain Sickness
    View official trial listing →
  • Completed NCT NCT02470039

    Trial to Compare NNC0123-0000-0338 in a Tablet Formulation and Insulin Glargine in Subjects With Type 2 Diabetes Currently Treated With Oral Antidiabetic Therapy

    Not yet reported Novo Nordisk A/S 50 participants Est. completion 2015-12-31 2 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT02470546

    Metformin Experience on Minimal Hepatic Encephalopathy

    Not yet reported Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 30 participants Est. completion 2016-12 1 site
    Other conditions: Liver Cirrhosis, Hepatic Encephalopathy
    View official trial listing →
  • Completed NCT NCT02471404

    Efficacy and Safety of Dapagliflozin and Dapagliflozin Plus Saxagliptin in Combination With Metformin in Type 2 Diabetes Patients Compared With Sulphonylurea

    Not yet reported AstraZeneca 939 participants Est. completion 2017-03-13 173 sites
    Type 2 diabetes Other conditions: Inadequate Glycaemic Control
    View official trial listing →
  • Terminated NCT NCT02472353

    Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer

    Not yet reported Avera McKennan Hospital & University Health Center 30 participants Est. completion 2018-05-23 1 site Stand-alone
    Other conditions: Breast Cancer, Breast Tumors
    View official trial listing →
  • Terminated NCT NCT02473094

    Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer

    Not yet reported University of Campinas, Brazil 3 participants Est. completion 2016-02 1 site Stand-alone
    Other conditions: Rectal Neoplasms, Adenocarcinoma, Carcinoma
    View official trial listing →
  • Completed NCT NCT02475070

    Vildagliptin Versus Dapagliflozin on Glucagon

    Not yet reported Lund University 28 participants Est. completion 2017-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02475499

    Incretin-based Drugs and Pancreatic Cancer

    Canadian Network for Observational Drug Effect Studies, CNODES 886172 participants Est. completion 2015-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02476760

    Incretin-based Drugs and Acute Pancreatitis

    Canadian Network for Observational Drug Effect Studies, CNODES 1417914 participants Est. completion 2015-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02477969

    Efficacy and Safety Study of PEX168 in Combination Therapy Diabetes Mellitus Type 2 Patients With Metformin

    Not yet reported Jiangsu Hansoh Pharmaceutical Co., Ltd. 587 participants Est. completion 2017-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02480465

    Efficacy and Safety of Lobeglitazone Versus Sitagliptin

    Not yet reported Chong Kun Dang Pharmaceutical 248 participants Est. completion 2017-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02483299

    Liraglutide as Add on Therapy on Metformin in Women With Polycystic Ovary Syndrome

    Not yet reported University Medical Centre Ljubljana 40 participants Est. completion 2015-04 1 site
    Other conditions: PCOS, Obesity
    View official trial listing →
  • Withdrawn NCT NCT02484209

    DiaFrail: A Short Duration Study in Older People ( DIAFRAIL Study)

    Not yet reported Diabetes Frail Ltd Est. completion 2016-11 Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02488564

    A Study of Liposomal Doxorubicin+Docetaxel+Trastuzumab+Metformin in Operable and Locally Advanced HER2 Positive Breast Cancer

    Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 49 participants Est. completion 2020-03-17 9 sites Stand-alone
    Other conditions: HER-2 Positive Breast Cancer
    View official trial listing →
  • Completed NCT NCT02491333

    The RCT of Acupuncture on PCOS Combined With IR

    Not yet reported The First Affiliated Hospital of Guangzhou Medical University 342 participants Est. completion 2018-10 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Terminated NCT NCT02495103

    Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma

    Not yet reported, Not yet reported National Cancer Institute (NCI) 7 participants Est. completion 2020-02-06 1 site Stand-alone
    Other conditions: Renal Cell Carcinoma, Hereditary Leiomyomatosis, Renal Cell Cancer
    View official trial listing →
  • Completed NCT NCT02496000

    Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus

    Not yet reported Oramed, Ltd. 188 participants Est. completion 2016-09-13 34 sites
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT02496741

    Metformin And Chloroquine in IDH1/2-mutated Solid Tumors

    Not yet reported, Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 15 participants Est. completion 2019-11-18 3 sites Stand-alone
    Obstructive sleep apnea Other conditions: Glioma, Cholangiocarcinoma
    View official trial listing →
  • Completed NCT NCT02497313

    Effect of Metformin and Cholecystokinin-mediated Gallbladder Emptying on GLP-1 Secretion in Type 2 Diabetes

    Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2016-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02498522

    Effect of Metformin on Early Pregnancy Loss in Pregnant Women With Polycystic Ovarian Syndrome

    Not yet reported Ain Shams University 166 participants Est. completion 2016-03 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Terminated NCT NCT02500147

    Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)

    Not yet reported Columbia University 3 participants Est. completion 2021-03-03 1 site Stand-alone
    Metabolic syndrome Other conditions: Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease
    View official trial listing →
  • Completed NCT NCT02500628

    Heart Rate Variability in Response to Metformin Challenge

    Not yet reported Woodinville Psychiatric Associates 61 participants Est. completion 2016-02 1 site Stand-alone
    Type 2 diabetes Other conditions: Fibromyalgia, Mitochondrial Diseases, Movement Disorders
    View official trial listing →
  • Status unknown NCT NCT02501616

    Effect of Dapagliflozine on Systemic and Renal Endothelial Function

    Not yet reported Seoul National University Hospital 22 participants 1 site
    Type 2 diabetes Other conditions: Endothelial Function
    View official trial listing →
  • Status unknown NCT NCT02501850

    The Effect of the GLP-1 Receptor Agonists on Blood Levels of Lipoprotein (a)

    Not yet reported Hospital Universitari Vall d'Hebron Research Institute 40 participants Est. completion 2015-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02502344

    Effect of Medical Interventions in Insulin Resistance on Prevalence of Abnormal Glucose Tolerance

    Not yet reported Beijing Tsinghua Chang Gung Hospital 60 participants 1 site Stand-alone
    Other conditions: Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT02503943

    Effects of Incretin on the Blood Pressure and Lipid in Patients With Overweight or Obese Diabetes

    Not yet reported Third Affiliated Hospital of Third Military Medical University 90 participants Est. completion 2016-09
    Type 2 diabetes Other conditions: Overweight, Obesity, Masked Hypertension
    View official trial listing →
  • Completed NCT NCT02505516

    BLADDER CANCER SCREENING AMONG DIABETIC PATIENTS

    Not yet reported UFUOMA MILLER FAKPOR 150 participants Est. completion 2014-02 1 site
    Other conditions: Bladder Cancer, Diabetes
    View official trial listing →
  • Status unknown NCT NCT02506777

    Neoadjuvant FDC With Melatonin or Metformin for Locally Advanced Breast Cancer.

    Not yet reported N.N. Petrov National Medical Research Center of Oncology 96 participants Est. completion 2020-08 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT02506790

    Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer

    Not yet reported N.N. Petrov National Medical Research Center of Oncology 96 participants Est. completion 2022-08 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT02511665

    Metformin And Longevity

    Not yet reported Guy's and St Thomas' NHS Foundation Trust 185 participants Est. completion 2017-07 1 site Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT02512523

    Exploratory Study to Compare the Effects of Tenelia® or Januvia® on Glucose Variability in add-on to Metformin (CGMS Study)

    Not yet reported Handok Inc. 39 participants Est. completion 2016-09-26 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02514629

    Testosterone, Metformin, or Both, for Hypogonadism in Obese Males

    Not yet reported Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud 107 participants Est. completion 2016-07-12 1 site Stand-alone
    Other conditions: Hypogonadism, Obesity
    View official trial listing →
  • Completed NCT NCT02515773

    Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs

    Not yet reported Melissa Delbello 1565 participants Est. completion 2023-06 29 sites Stand-alone
    Other conditions: Bipolar Disorder
    View official trial listing →
  • Completed NCT NCT02516085

    Improved Muscle Function in Duchenne Muscular Dystrophy Through L-Arginine and Metformin

    Not yet reported University Hospital, Basel, Switzerland 5 participants Est. completion 2012-10 Stand-alone
    Other conditions: Duchenne Muscular Dystrophy
    View official trial listing →
  • Terminated NCT NCT02521753

    Omega 3 Polyunsaturated Fatty Acids (PUFA) or Magnesium in Obese Polycystic Ovary Syndrome Patients

    Not yet reported Coordinación de Investigación en Salud, Mexico 123 participants Est. completion 2025-03 1 site
    Other conditions: Polycystic Ovary Syndrome, Obesity
    View official trial listing →
  • Terminated NCT NCT02523898

    Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant

    Not yet reported Semnan University of Medical Sciences 388 participants Est. completion 2022-04 Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Hyperandrogenism
    View official trial listing →
  • Completed NCT NCT02524821

    The Effect of Gelesis100 on the Pharmacokinetics of Metformin

    Not yet reported Gelesis, Inc. 24 participants Est. completion 2015-12 1 site
    Other conditions: Healthy Overweight Obese
    View official trial listing →
  • Completed NCT NCT02526524

    Dose-Ranging Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Metformin Delayed Release in Subjects With T2DM

    Not yet reported Elcelyx Therapeutics, Inc. 571 participants Est. completion 2016-09 137 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02526615

    Effects of Rosiglitazone and Metformin on Metabolism in Type 2 Diabetes

    Not yet reported Turku University Hospital 48 participants Est. completion 2001-12 3 sites
    Type 2 diabetes Other conditions: Insulin Sensitivity
    View official trial listing →
  • Status unknown NCT NCT02526810

    Comparison of Glycaemic Fluctuation and Oxidative Stress Between Two Short-term Therapies for Type 2 Diabetes

    Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 70 participants Est. completion 2016-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02531308

    Metformin in Combination With Standard Induction Therapy for Large B-cell Lymphoma (DLBCL)

    Not yet reported Rush University Medical Center 5 participants Est. completion 2016-07 1 site Stand-alone
    Other conditions: Diffuse Large B-Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT02532855

    A Study to Assess the Addition of Sitagliptin to Metformin Compared With the Addition of Dapagliflozin to Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) and Mild Renal Impairment Who Have Inadequate Glycemic Control on Metformin With or Without a Sulfonylurea (MK-0431-838)

    Not yet reported Merck Sharp & Dohme LLC 614 participants Est. completion 2017-10-10 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02535299

    Par-4 and Telomere-telomerase System in Type 2 Diabetes Patients Who Received GLP-1 or Metformin Treatment

    Not yet reported Third Military Medical University 200 participants Est. completion 2019-12 1 site Added to GLP-1
    Other conditions: GLP-1;Metformin;Telomere-telomerase System;Par-4
    View official trial listing →
  • Status unknown NCT NCT02535975

    The Effects of Metformin in Patients With Mild Graves' Ophthalmopathy

    Not yet reported Yonsei University 80 participants Est. completion 2019-10 1 site
    Other conditions: Mild Graves' Ophthalmopathy
    View official trial listing →
  • Completed NCT NCT02546050

    The Effect of Metformin on Composition of Human Gut Bacteria

    Not yet reported Oluf Borbye Pedersen 26 participants Est. completion 2016-02 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02546609

    The Effect Of NS-0200 Versus Placebo On Hepatic Fat Content In Patients With Non Alcoholic Fatty Liver Disease

    Not yet reported NuSirt Biopharma 91 participants Est. completion 2017-01-31 13 sites Stand-alone
    MASLD
    View official trial listing →
  • Status unknown NCT NCT02548741

    Evaluation of the Metformin Effect on Methylglyoxal in Patients With Type 2 Diabetes

    Not yet reported University of Arizona 120 participants Est. completion 2017-08
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02549924

    Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus

    Not yet reported University of Guadalajara 22 participants Est. completion 2018-02-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02551874

    A 24-week Open-Label, Phase 3b Trial With a 28-week Extension to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin Compared to Insulin Glargine in Subjects withType 2 Diabetes Who Have Glycemic Control on Metformin

    Not yet reported AstraZeneca 650 participants Est. completion 2017-11-10 40 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02552355

    Milk Protein Feeding After Aerobic Exercise in Older Adults With Pre-diabetes Taking the Biguanide Metformin

    Not yet reported Colorado State University 56 participants Est. completion 2017-08 1 site Stand-alone
    Other conditions: Physical Activity
    View official trial listing →
  • Completed NCT NCT02554877

    A 12-week Study To Evaluate PF-06291874 Once a Day in Adults With T2DM Inadequately Controlled On Metformin

    Not yet reported Pfizer 206 participants Est. completion 2016-08 38 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02561130

    Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Forxiga

    Not yet reported Population Health Research Institute 154 participants Est. completion 2018-12-31 7 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02564926

    Foxiga Korea Local Phase 4 Study

    Not yet reported AstraZeneca 125 participants Est. completion 2018-01-15 14 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02565368

    A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.5/1000 mg in Healthy Male Volunteers

    Not yet reported Chong Kun Dang Pharmaceutical 26 participants Est. completion 2015-08 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Completed NCT NCT02565862

    A Drug-drug Interaction Study Between Daclatasvir and Metformin

    Not yet reported Radboud University Medical Center 20 participants Est. completion 2016-04 1 site Stand-alone
    Other conditions: Hepatitis C, Diabetes Mellitus, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT02567994

    Tenelia Triple Combination Study

    Not yet reported Handok Inc. 201 participants Est. completion 2017-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02570672

    Metformin for Preventing Frailty in High-risk Older Adults

    Not yet reported The University of Texas Health Science Center at San Antonio 141 participants Est. completion 2024-02-07 1 site Stand-alone
    Other conditions: Frailty
    View official trial listing →
  • Withdrawn NCT NCT02571608

    Continuation of Metformin to Improve And Keep Peri-operative Glycemic Control

    Not yet reported McMaster University Est. completion 2022-12-31
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02574845

    DDI (Effect of Metformin and Furosemide on Rosuvastatin PK)

    Not yet reported Boehringer Ingelheim 18 participants Est. completion 2015-12-14 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02580331

    1% Metformin Gel in the Treatment of Class II Furcation Defects

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 64 participants Est. completion 2015-09 1 site
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Active, not recruiting NCT NCT02581137

    Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion

    Not yet reported National Cancer Institute (NCI) 26 participants Est. completion 2026-12-19 4 sites Stand-alone
    Other conditions: Erythroplakia, Hyperplasia, Oral Cavity Carcinoma, Oral Leukoplakia
    View official trial listing →
  • Completed NCT NCT02582242

    Comparing Efficacy and Safety of Thrice Daily Versus Twice Daily NovoMix® 30 (Biphasic Insulin Aspart 30) in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin

    Not yet reported Novo Nordisk A/S 437 participants Est. completion 2017-04-18 50 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02583919

    Safety, Tolerability and Efficacy of ISIS-GCGRRx in Patients With Type 2 Diabetes

    Not yet reported Ionis Pharmaceuticals, Inc. 79 participants Est. completion 2017-05-11 19 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02584075

    Evaluate the Effect of Exenatide Treatment on Coronary Artery Endothelial Function

    Not yet reported Beijing Chao Yang Hospital 100 participants Est. completion 2018-01 Added to GLP-1
    Other conditions: Coronary Endothelial Function
    View official trial listing →
  • Completed NCT NCT02586129

    Clinical Trial of YH14755 in Subjects With Dyslipidemia and Type II Diabetes

    Not yet reported Yuhan Corporation 249 participants Est. completion 2017-07-07 1 site
    Other conditions: Dyslipidemia, Type II Diabetes
    View official trial listing →
  • Completed NCT NCT02586636

    Impact of OCT1 on Metformin Tolerance

    Not yet reported NHS Tayside 61 participants Est. completion 2018-04-09 1 site
    Other conditions: Tolerance
    View official trial listing →
  • Status unknown NCT NCT02587741

    Comparison of Diabetes Retinopathy Among Type 2 Diabetic Patients Treated With Different Regimens

    Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 600 participants Est. completion 2025-07 1 site Stand-alone
    Other conditions: Diabetic Retinopathy
    View official trial listing →
  • Completed NCT NCT02588859

    Study to Understand Usage and Effect of Saxagliptin as First Add-On After Metformin in Indian Type 2 Diabetes Mellitus Patients

    AstraZeneca 1200 participants Est. completion 2016-12-26 31 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02593097

    Metformin for the Prevention of Episodic Migraine (MPEM)

    Not yet reported Mayo Clinic 34 participants Est. completion 2019-06 1 site Stand-alone
    Other conditions: Migraine
    View official trial listing →
  • Completed NCT NCT02597049

    A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 424 participants Est. completion 2017-02 41 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02597101

    Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes

    Not yet reported Nick Giannoukakis, PhD 14 participants Est. completion 2019-06-15 1 site Stand-alone
    Type 2 diabetes Other conditions: Insulin Resistance
    View official trial listing →
  • Completed NCT NCT02597400

    Drug-Drug Interaction Study of Glucokinase Activator HMS5552 and Metformin in T2DM

    Not yet reported Hua Medicine Limited 12 participants Est. completion 2015-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02607410

    Sitagliptin (DPP-4 Inhibitor) and NPH Insulin in Patients With T2D

    Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2014-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02609815

    Initial Combination of Gemigliptin and Metformin on Microbiota Change

    Not yet reported Seoul National University Bundang Hospital 70 participants Est. completion 2021-03-15 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02611518

    A Pharmacokinetic Interaction Study Between JNJ-54861911 and Transporter Substrates Rosuvastatin and Metformin in Healthy Participants

    Not yet reported Janssen Research & Development, LLC 32 participants Est. completion 2016-06-14 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02613897

    ESR-15-11293 - Saxa/Dapa, Safety and Efficacy Study

    Not yet reported The University of Texas Health Science Center at San Antonio 56 participants Est. completion 2018-06-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02614339

    Effect of Adjunctive Metformin on Recurrence of Non-DM Colorectal Cancer Stage II High-risk/ III Colorectal Cancer

    Not yet reported Yonsei University 593 participants Est. completion 2021-07 1 site Stand-alone
    Other conditions: Non-DM Stage II High-risk Colorectal Cancer, Non-DM Stage III Colorectal Cancer
    View official trial listing →
  • Completed NCT NCT02614859

    Bicalutamide With or Without Metformin for Biochemical Recurrence in Overweight or Obese Prostate Cancer Patients

    Not yet reported Fox Chase Cancer Center 29 participants Est. completion 2020-01-24 2 sites Stand-alone
    Other conditions: Cancer of Prostate
    View official trial listing →
  • Completed NCT NCT02616666

    A Pragmatic Randomized Trial to Evaluate the Comparative Effectiveness Between Dapagliflozin and Standard of Care in Type 2 Diabetes Patients

    Not yet reported University of Liverpool 632 participants Est. completion 2025-12-12 132 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02621489

    Effects on Re-endothelialisation With Bydureon Treatment in Type 2 Diabetes Subjects

    Not yet reported Karolinska Institutet 38 participants Est. completion 2022-10 1 site Added to GLP-1
    Other conditions: Atherosclerosis, Diabetes, Restenosis
    View official trial listing →
  • Completed NCT NCT02623998

    Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Sitagliptin (REMIT-Sita)

    Not yet reported Population Health Research Institute 102 participants Est. completion 2019-11-30 6 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02627027

    A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.25/750 mg in Healthy Male Volunteers

    Not yet reported Chong Kun Dang Pharmaceutical 26 participants Est. completion 2015-09 1 site
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Completed NCT NCT02627898

    Effect of Green Tea Extract on Arterial Stiffness in Type 2 Diabetes Mellitus

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2016-12 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02629627

    Conjugated Linoleic Acid / Leucine Versus Metformin on Visceral Fat in Metabolic Syndrome

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 104 participants Est. completion 2017-10 Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT02630706

    A Study to Evaluate the Efficacy and Safety of Ertugliflozin in Asian Participants With Type 2 Diabetes and Inadequate Glycemic Control on Metformin Monotherapy (MK-8835-012)

    Not yet reported Merck Sharp & Dohme LLC 506 participants Est. completion 2017-12-27 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02633488

    Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic Syndrome

    Not yet reported University of Virginia 19 participants Est. completion 2016-07 1 site Stand-alone
    Metabolic syndrome Other conditions: Insulin Sensitivity
    View official trial listing →
  • Completed NCT NCT02635386

    EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)

    Not yet reported Woman's 119 participants Est. completion 2020-10-09 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Obesity
    View official trial listing →
  • Completed NCT NCT02635646

    Interdisciplinary and Family Intervention to Prevent Type 2 Diabetes

    Not yet reported Universidad de Guanajuato 122 participants Est. completion 2017-02 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Completed NCT NCT02637037

    A Study to Assess the Bioequivalence of Dapagliflozin/Metformin XR Fixed-dose Combination Tablets in Healthy Subjects

    Not yet reported AstraZeneca 80 participants Est. completion 2016-04-07 1 site Stand-alone
    Other conditions: Bioequivalence, Fixed Dose Combination Tablets, Healthy Male and Female Subjects
    View official trial listing →
  • Completed NCT NCT02638805

    Study of the Safety and Tolerability of Switching to ITCA 650 in Patients With Type 2 Diabetes Receiving Liraglutide

    Not yet reported Intarcia Therapeutics 136 participants Est. completion 2017-10 36 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02640534

    Investigation of Metformin in Patients With Castration Resistant Prostate Cancer in Combination With Enzalutamide vs. Enzalutamide Alone

    Not yet reported Swiss Cancer Institute 169 participants Est. completion 2023-03-16 16 sites Stand-alone
    Other conditions: Cancer of the Prostate, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT02644577

    Metformin for Treatment Antipsychotic-induced Metabolic Syndrome in Bipolar Disorder Patients

    Not yet reported China Medical University, China 110 participants Est. completion 2015-09 1 site Stand-alone
    Other conditions: Bipolar Disorder
    View official trial listing →
  • Status unknown NCT NCT02644954

    Assessing the Efficacy and Safety of Metformin in Treatment of Moderate Psoriasis

    Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 40 participants
    Other conditions: Psoriasis
    View official trial listing →
  • Completed NCT NCT02647320

    12-Week Study of DS-8500a in Subjects With Type 2 Diabetes Mellitus on Metformin

    Not yet reported Daiichi Sankyo 298 participants Est. completion 2017-01-31 58 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02648854

    Investigate the Effect of Food on the Pharmacokinetic Characteristics of CKD-395 in Healthy Male Volunteers

    Not yet reported Chong Kun Dang Pharmaceutical 26 participants Est. completion 2015-11 1 site
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Completed NCT NCT02653209

    TriMaster: Study of a DPP4 Inhibitor, SGLT2 Inhibitor and Thiazolidinedione as Third Line Therapy in Patients With Type 2 Diabetes.

    Not yet reported Royal Devon and Exeter NHS Foundation Trust 525 participants Est. completion 2021-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02653599

    A Study to Evaluate Safety and Efficacy of TTP273 for 12 Weeks in Subjects With Type 2 Diabetes

    Not yet reported vTv Therapeutics 174 participants Est. completion 2017-01 30 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02656017

    Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease

    Not yet reported Kyongtae Ty Bae, M.D., Ph.D. 97 participants Est. completion 2020-12-07 2 sites Stand-alone
    Other conditions: Polycystic Kidney, Autosomal Dominant
    View official trial listing →
  • Completed NCT NCT02659306

    Metformin Immunotherapy in HIV Infection

    Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 22 participants Est. completion 2020-02 1 site Stand-alone
    Other conditions: HIV Infection
    View official trial listing →
  • Status unknown NCT NCT02670018

    BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 2000mg in Comparison to Each Component Administered Alone

    Not yet reported LG Life Sciences 25 participants Est. completion 2016-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02672488

    Metformin Plus Sorafenib for Advanced HCC

    Not yet reported Tianjin Medical University Cancer Institute and Hospital 82 participants Est. completion 2018-12 1 site Stand-alone
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT02681094

    A Multi-Center, Randomized, Double-Blind, Phase III Trial to Evaluate the Safety and Efficacy of Saxagliptin Co-administered With Dapagliflozin Compared to Saxagliptin or Dapagliflozin All Given as add-on Therapy to Metformin in Subject With Type 2 Diabetes

    Not yet reported AstraZeneca 905 participants Est. completion 2017-07-15 110 sites
    Type 2 diabetes Other conditions: Inadequate Glycaemic Control
    View official trial listing →
  • Completed NCT NCT02682121

    Mitochondrial-related Platelet Transcript Expression Levels in Pre-diabetic Subjects Randomized to Metformin or Placebo

    Not yet reported University of Utah 55 participants Est. completion 2017-01 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT02682563

    Renoprotective Effects of Dapagliflozin in Type 2 Diabetes

    Not yet reported M.H.H. Kramer 44 participants Est. completion 2018-09 1 site
    Type 2 diabetes Other conditions: Diabetic Nephropathies
    View official trial listing →
  • Completed NCT NCT02683226

    Comparison of Alogliptin Versus Alogliptin and Pioglitazone on Insulin Resistance of Metformin Treated Women With PCOS

    Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2015-07 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT02684578

    Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMD

    Not yet reported University of California, San Francisco 66 participants Est. completion 2022-10 12 sites Stand-alone
    Other conditions: Age-Related Macular Degeneration, Macular Degeneration, Age-Related, Dry Macular Degeneration, Geographic Atrophy
    View official trial listing →
  • Completed NCT NCT02685774

    A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.25/500mg in Healthy Male Volunteers

    Not yet reported Chong Kun Dang Pharmaceutical 26 participants Est. completion 2016-04 1 site
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Completed NCT NCT02686177

    Effect of GLP-1 on Angiogenesis

    Not yet reported Assistance Publique - Hôpitaux de Paris 50 participants Est. completion 2021-05-28 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02686476

    Effect of Empagliflozin on Liver Fat Content in Patients With Type 2 Diabetes

    Not yet reported Medanta, The Medicity, India 100 participants Est. completion 2017-12 1 site
    Other conditions: Non Alcoholic Fatty Liver Disease
    View official trial listing →
  • Completed NCT NCT02689843

    Effects of Cyproterone Compound-spironolactone, Metformin and Pioglitazone on Inflammatory Markers in PCOS

    Not yet reported Shiraz University of Medical Sciences 90 participants Est. completion 2018-12-30 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02693392

    Clinical Evaluation of Fenugreek Seed Extract, a Nutraceutical in Patients With Type- 2 Diabetes

    Not yet reported All India Institute of Medical Sciences, Bhubaneswar 200 participants Est. completion 2018-08-16 1 site Stand-alone
    Other conditions: Type-2 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02694263

    Canagliflozin (Invokana™) vs. Standard Dual Therapy Regimen for T2DM During Ramadan

    Not yet reported University of Leicester 25 participants Est. completion 2018-09-13 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT02694289

    Effects of Metformin in Heart Failure Patients

    Not yet reported Maya Guglin Est. completion 2018-09-10
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02695121

    Cancer in Patients on Dapagliflozin and Other Antidiabetic Treatment

    AstraZeneca 2133575 participants Est. completion 2025-01-30 4 sites
    Other conditions: Breast Cancer, Bladder Cancer
    View official trial listing →
  • Completed NCT NCT02695810

    The PRE-D Trial: Effect of Dapagliflozin, Metformin and Physical Activity in Pre-diabetes

    Not yet reported Steno Diabetes Center Copenhagen 120 participants Est. completion 2019-01-13 1 site
    Other conditions: Prediabetic State, Obesity
    View official trial listing →
  • Completed NCT NCT02696941

    SGLT2 Inhibitors and Metformin on Metabolism and Non-Alcoholic SteatoHepatitis

    Not yet reported University of Oxford 20 participants Est. completion 2018-04-01 1 site Stand-alone
    Other conditions: Non-alcoholic Fatty Liver Disease
    View official trial listing →
  • Status unknown NCT NCT02708758

    Efficacy of Treatment for Gestational Diabetes Diagnosed by the IADPSG Criteria.

    Not yet reported Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes 400 participants Est. completion 2021-12 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT02710448

    May Metformin be Used in Renal Failure?

    Not yet reported Centre Hospitalier Universitaire, Amiens 82 participants Est. completion 2015-10 1 site Stand-alone
    Other conditions: Renal Disorder Associated With Type II Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02712619

    Pharmacokinetic-Pharmacodynamic Relationship of Metformin in Healthy Volunteers

    Not yet reported Seoul National University Hospital 20 participants Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Withdrawn NCT NCT02719132

    Effect of DapagliFLOzin on Quality of Life in Patients With Type 2 Diabetes in a Real Clinical PrActice

    Not yet reported AstraZeneca Est. completion 2017-11 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02719756

    Effect of SGLT-2 Inhibitor Dapagliflozin on Glycemic Variability in Patients With Diabetes Mellitus Type 2

    Not yet reported Research Clinical Centre of the Russian Railways, JSC 100 participants Est. completion 2016-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Hypoglycemic Episodes
    View official trial listing →
  • Completed NCT NCT02722239

    An Open-label, Randomized, Crossover Study of Comparative Pharmacokinetics and Bioequivalence of Dapagliflozin + Metformin, 10 mg + 1000 mg Versus the Combined Use of Forxiga™, 10 mg and Two Glucophage® Long, ER Tablets, 500 mg Co-administered to Healthy Volunteers Under Standard Fed Conditions

    Not yet reported AstraZeneca 40 participants Est. completion 2016-05-05 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02726490

    Glyburide vs Glucovance in the Treatment of GDM

    Not yet reported Texas Tech University Health Sciences Center, El Paso 7 participants Est. completion 2018-08-14 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT02730377

    Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 1991 participants Est. completion 2019-08-12 232 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT02730741

    Study of the Efficacy and Tolerance of Oral Treatment With a Total Freeze-dried Culture of Lcr Restituo® Sachets (Lactobacillus Rhamnosus Lcr35®) on Intolerance to Metformin (Diarrhoea) in Patients With Diabetes Type 2

    Not yet reported Biose 60 participants 1 site
    Other conditions: Antidiarrhoea
    View official trial listing →
  • Completed NCT NCT02733679

    Response of Individuals With Ataxia-Telangiectasia to Metformin and Pioglitazone

    Not yet reported NHS Tayside 27 participants Est. completion 2017-08-30 1 site Stand-alone
    Other conditions: Ataxia-Telangiectasia
    View official trial listing →
  • Completed NCT NCT02737657

    An Observational Study to Evaluate Tolerability of Canagliflozin and Sulphonylurea in Type 2 Diabetes Patients During Ramadan

    Janssen-Cilag International NV 379 participants Est. completion 2016-09 9 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02738879

    Randomized Sitagliptin Withdrawal Study (MK-0431-845)

    Not yet reported Merck Sharp & Dohme LLC 746 participants Est. completion 2018-01-30 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02741960

    The Effect of Metformin on Reducing Lupus Flares

    Not yet reported RenJi Hospital 180 participants Est. completion 2018-12-07 1 site Stand-alone
    Other conditions: Systemic Lupus Erythematosus
    View official trial listing →
  • Completed NCT NCT02743260

    Drug Transporter Interaction Study PHENTRA_2015_KPUK

    Not yet reported University of Cologne 24 participants Est. completion 2017-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02744131

    OCP vs Metformin for Improvement in Clinical Symptoms and Metabolic Markers in Indian PCOS Women

    Not yet reported Kar Clinic & Hospital Pvt. Ltd. 100 participants Est. completion 2019-12 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02744976

    Coronary Artery Disease Progression in Patients With Prediabetes

    Not yet reported Pauls Stradins Clinical University Hospital 70 participants Est. completion 2021-09 1 site Stand-alone
    Cardiovascular disease Other conditions: Atherosclerosis, Prediabetic State
    View official trial listing →
  • Status unknown NCT NCT02745886

    Metformin Induces a Dietary Restriction-like State in Human

    Not yet reported Xiang Guang-da 60 participants Est. completion 2016-12 1 site Stand-alone
    Other conditions: Overweight Subjects, Metformin, Aging
    View official trial listing →
  • Completed NCT NCT02745912

    Study to Evaluate the Effect of Naltrexone and Bupropion Combination on the Pharmacokinetics of Metformin in Healthy Participants

    Not yet reported Orexigen Therapeutics, Inc 30 participants Est. completion 2016-08 Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT02749032

    Feed-Back Suppression of Meal-Induced Glucagon-like Peptide 1 (GLP-1) Secretion

    Not yet reported Michael A. Nauck 24 participants 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02751307

    Adjunctive Low-dose Metformin in Patients With Schizophrenia and Metabolic Abnormalities

    Not yet reported Taipei Medical University WanFang Hospital 55 participants Est. completion 2015-01
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT02752113

    Effects of Empagliflozin + Linagliptin vs Metformin + Insulin Glargine on Renal and Vascular Changes in Type 2 Diabetes

    Not yet reported Institut für Pharmakologie und Präventive Medizin 101 participants Est. completion 2019-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02752412

    Efficacy and Safety of LixiLan Versus Insulin Glargine Alone Both With Metformin in Japanese With Type 2 Diabetes Mellitus Inadequately Controlled on Basal Insulin and Oral Antidiabetic Drugs

    Not yet reported Sanofi 513 participants Est. completion 2018-10-04 122 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02755844

    Safety and Efficacy of Metronomic Cyclophosphamide, Metformin and Olaparib in Endometrial Cancer Patients

    Not yet reported, Not yet reported Hospices Civils de Lyon 35 participants Est. completion 2020-06 6 sites Stand-alone
    Other conditions: Recurrent Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT02760342

    A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Metformin

    Not yet reported Astellas Pharma Inc 24 participants Est. completion 2016-06-26 1 site Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Terminated NCT NCT02763007

    An Extension Study of PEAK Trial

    Not yet reported Kun-Ho Yoon 41 participants Est. completion 2019-02-28 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02765347

    The Effects of Metformin on Glycemic Control and Insulin Sensitivity in Adolescents With T1DM

    Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 30 participants Est. completion 2018-01 1 site
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT02769481

    Safety and Efficacy of Bexagliflozin Compared to Glimepiride as Add-on Therapy to Metformin in Type 2 Diabetes Subjects

    Not yet reported Theracos 426 participants Est. completion 2019-06-14 45 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02773927

    Combination of Metformin/Inulin vs Inulin on Adiponectin in Metabolic Syndrome

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 40 participants Est. completion 2015-06 1 site Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT02778776

    Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic Syndrome

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 40 participants Est. completion 2015-06 1 site Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT02783053

    Metformin and Core Temperature in Obese and Lean Males

    Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 18 participants Est. completion 2016-06 1 site
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT02786823

    Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes

    Not yet reported, Not yet reported All India Institute of Medical Sciences, Bhubaneswar 80 participants Est. completion 2017-09-15 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02787551

    Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period

    Not yet reported Sanofi 514 participants Est. completion 2018-11-17 124 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02791490

    A Study of the Safety and Efficacy of Sitagliptin Addition During Metformin Up-titration (MK-0431-848)

    Not yet reported Merck Sharp & Dohme LLC 458 participants Est. completion 2018-02-01 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02793505

    Safety of Metformin in Pregnancy

    Centre Hospitalier Universitaire Vaudois 950 participants
    Other conditions: Pregnancy, Pregestational Diabetes, Polycystic Ovary Syndrom
    View official trial listing →
  • Completed NCT NCT02794792

    A Study to Assess the Efficacy and Safety of Ipragliflozin in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin

    Not yet reported Astellas Pharma Europe B.V. 268 participants Est. completion 2017-06-20 14 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02796144

    MEtformin and Lorcaserin for WeighT Loss in Schizophrenia

    Not yet reported University of North Carolina, Chapel Hill 71 participants Est. completion 2020-02-14 4 sites
    Other conditions: Schizophrenia, Schizoaffective Disorder, Overweight
    View official trial listing →
  • Completed NCT NCT02798172

    The Effect of Alogliptin on Pulmonary Function in Obese Patients With Type 2 Diabetes Inadequately Controlled by Metformin Monotherapy

    Not yet reported Fourth People's Hospital of Shenyang 81 participants Est. completion 2015-08 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02802215

    Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome

    Not yet reported, Not yet reported Ain Shams University 80 participants Est. completion 2016-09 1 site
    Other conditions: Polycystic Ovary Syndrome, Diabetes, Gestational
    View official trial listing →
  • Completed NCT NCT02803918

    A Study on Safety, Pharmacokinetics and Pharmacodynamics of Lixisenatide in Pediatric Patients With Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Sanofi 23 participants Est. completion 2020-01-27 11 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02805283

    Dapagliflozin Patient Satisfaction Survey

    AstraZeneca 653 participants Est. completion 2018-10-29 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02810132

    Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failure

    Not yet reported Aarhus University Hospital 36 participants Est. completion 2018-02-14 1 site
    Heart failure
    View official trial listing →
  • Completed NCT NCT02813863

    The Drug-drug Interaction of SP2086 and Metformin

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 24 participants Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02815397

    DA-EPOCH-Rituximab/Metformin (RM) for Double Hit Lymphoma

    Not yet reported Rush University Medical Center 2 participants Est. completion 2016-07 1 site Stand-alone
    Other conditions: Diffuse Large B-Cell Lymphoma
    View official trial listing →
  • Terminated NCT NCT02819869

    The Combination Effect of Statin Plus Metformin on Relapse-free

    Not yet reported Taipei Medical University WanFang Hospital 3 participants Est. completion 2016-12-14 1 site Stand-alone
    Other conditions: Hepatocellular Carcinoma
    View official trial listing →
  • Completed NCT NCT02821910

    Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Linagliptin/Metformin Extended Release Compared With Single Tablets

    Not yet reported Boehringer Ingelheim 50 participants Est. completion 2016-10-31 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02823691

    The MetNET-2 Trial

    Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 20 participants Est. completion 2021-12 1 site Stand-alone
    Other conditions: Neuroendocrine Tumors
    View official trial listing →
  • Status unknown NCT NCT02823808

    Effect of Alogliptin/Pioglitazone on the Preservation of Long-term Beta-cell Function

    Not yet reported Kyunghee University Medical Center 96 participants Est. completion 2021-12 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02824003

    Study to Evaluate the Effect of ISIS GCGRRx on Hepatic Lipid and Glycogen Content in Type 2 Diabetes

    Not yet reported Ionis Pharmaceuticals, Inc. 15 participants Est. completion 2017-05-22 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02827903

    Metformin/Rosuvastatin Combination Therapy With in Patients With Type 2 Diabetes and Dyslipidemia

    Not yet reported Jeil Pharmaceutical Co., Ltd. 237 participants Est. completion 2018-03-16 33 sites Stand-alone
    Type 2 diabetes Other conditions: Dyslipidemia
    View official trial listing →
  • Completed NCT NCT02831361

    Trial to Evaluate the Efficacy and Safety of Gemigliptin Compared With Placebo Added on Insulin Alone or on Insulin in Combination With Metformin in Type 2 DM (ZEUS II Study)

    Not yet reported LG Life Sciences 290 participants Est. completion 2018-02-08 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02836704

    Comparison of Standard vs Higher Starting Dose of Insulin Glargine in Chinese Patients With Type 2 Diabetes (Glargine Starting Dose)

    Not yet reported Sanofi 892 participants Est. completion 2018-04-26 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02844153

    Metformin Use in Chronic Kidney Disease: The CKD-Met Study

    Hospices Civils de Lyon 1000 participants Est. completion 2020-03 1 site
    Type 2 diabetesChronic kidney disease
    View official trial listing →
  • Status unknown NCT NCT02844803

    Study of Metformin and S. Baicalensis Combination Therapy in Type 2 Diabetes Mellitus Patients

    Not yet reported Namyi Gu 20 participants 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02846233

    Stepping-down Approach in Patients With Chronic Poorly-controlled Diabetes on Advanced Insulin Therapy?

    Not yet reported University of California, San Francisco 22 participants Est. completion 2018-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02846506

    A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants

    Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-10 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Withdrawn NCT NCT02848508

    Metformin in Moderate and Severe Renal Failure (CKD 3-4): A Follow-up Study

    Not yet reported Centre Hospitalier Universitaire, Amiens Est. completion 2017-06-07 1 site Stand-alone
    Other conditions: Renal Insufficiency, Chronic
    View official trial listing →
  • Status unknown NCT NCT02848950

    The Effect of Metformin on Fecundability in an ART(Assisted Reproductive Technology) Setting - the Correlation to Uterine Flows

    Not yet reported The Baruch Padeh Medical Center, Poriya 100 participants Est. completion 2017-07
    Other conditions: Infertility Female
    View official trial listing →
  • Completed NCT NCT02851095

    A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

    Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02851212

    A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin Extended Release Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

    Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-10 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02853630

    A Clinical Trial to Study the Effects of Two Drugs, Vildagliptin and Metformin in Patients With Type 2 Diabetes Mellitus

    Not yet reported India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals 203 participants Est. completion 2018-12 6 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02854527

    Transporter Cocktail Mutual Interaction

    Not yet reported Boehringer Ingelheim 30 participants Est. completion 2016-11-19 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02856113

    Phase 3 Alogliptin Pediatric Study

    Not yet reported Takeda 152 participants Est. completion 2022-02-14 67 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02865668

    A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants

    Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-10 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02866786

    The Effects of OCP and Metformin on Clinical, Hormonal, Metabolic and Ultrasonographic Characteristics in PCOS

    Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2017-08-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02872818

    Apoptotic Signaling Pathways in Rats With Endometrial Hyperplasia

    Not yet reported Kayseri Education and Research Hospital 40 participants Est. completion 2015-03 1 site
    Other conditions: Apoptotic Signal Pathways in Endometrial Hyperplasia
    View official trial listing →
  • Terminated NCT NCT02874430

    Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 29 participants Est. completion 2020-12-11 1 site Stand-alone
    Obstructive sleep apnea Other conditions: Breast Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Uterine Corpus Cancer
    View official trial listing →
  • Completed NCT NCT02875821

    Effects of Ipragliflozin on Excessive Fat in Type 2 Diabetes Patients With Non-alcoholic Fatty Liver Disease Treated With Metformin and Pioglitazone

    Not yet reported Yonsei University 44 participants Est. completion 2017-06-07 1 site
    MASLDType 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT02879409

    HbA1c Variability in Type II Diabetes

    Not yet reported Weill Cornell Medical College in Qatar 150 participants Est. completion 2026-10-01 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT02881528

    Autoimmune Diabetes Accelerator Prevention Trial

    Not yet reported University of Exeter Est. completion 2017-12-22 5 sites Stand-alone
    Other conditions: Prediabetic State
    View official trial listing →
  • Status unknown NCT NCT02882477

    Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based Therapy

    Not yet reported, Not yet reported Hadassah Medical Organization 20 participants Est. completion 2018-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Iron Metabolism Disorders, Gastroduodenal Ulcer, Optic Atrophy, Sensorineural Hearing Loss, Platelet Dysfunction
    View official trial listing →
  • Completed NCT NCT02882581

    Metformin in Breast Cancer, Visualized With Positron Emission Tomography

    Not yet reported Aarhus University Hospital 7 participants Est. completion 2017-10 2 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT02884089

    A Study of the Effect of Abemaciclib on Metformin and Iohexol in Healthy Participants

    Not yet reported Eli Lilly and Company 40 participants Est. completion 2016-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT02887625

    Exenatide Plus Pioglitazone Versus Insulin in Poorly Controlled T2DM

    Not yet reported Dr. Muhammad Abdulghani 410 participants Est. completion 2017-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02895750

    Efficacity and Safety of Metformin XR in CKD Stage 1 to 3

    Not yet reported Centre Hospitalier Universitaire, Amiens 12 participants Est. completion 2022-10-10 1 site Stand-alone
    Other conditions: Renal Insufficiency, Chronic
    View official trial listing →
  • Completed NCT NCT02897349

    Linagliptin Add-on to Insulin Background Therapy

    Not yet reported Boehringer Ingelheim 206 participants Est. completion 2019-01-18 25 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02903511

    Feasibility Study of Metformin Therapy in ADPKD

    Not yet reported University of Colorado, Denver 56 participants Est. completion 2020-08-17 1 site Stand-alone
    Other conditions: Polycystic Kidney, Autosomal Dominant
    View official trial listing →
  • Completed NCT NCT02909933

    Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of Obesity

    Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2015-10 1 site Added to GLP-1
    Other conditions: Polycystic Ovary Syndrome, Obesity
    View official trial listing →
  • Completed NCT NCT02910817

    Impact of Metformin on In Vitro Fertilization Outcomes in Overweight and Obese PCOS Women

    Not yet reported Assiut University 102 participants Est. completion 2016-12 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02911792

    Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With Hyperfiltration

    Not yet reported The University of Texas Health Science Center at San Antonio 72 participants Est. completion 2023-07-11 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02911948

    A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic Drugs

    Not yet reported Novo Nordisk A/S 210 participants Est. completion 2017-11-22 38 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02919345

    Assessment of Dapagliflozin Effect on Diabetic Endothelial Dysfunction of Brachial Artery

    Not yet reported University of Campinas, Brazil 98 participants Est. completion 2019-03 1 site Stand-alone
    Type 2 diabetesCardiovascular disease Other conditions: Carotid Artery Diseases
    View official trial listing →
  • Completed NCT NCT02920801

    Study About Effect of Saxagliptin on Circulating Endothelial Progenitor Cells and Endothelial Function in Newly Diagnosed Type 2 Diabetic Patients

    Not yet reported Shanghai Zhongshan Hospital 31 participants Est. completion 2015-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02922179

    Descriptive Analysis of Long- and Intermediate-Acting Insulin in Adult Diabetics

    Biologics & Biosimilars Collective Intelligence Consortium 103951 participants Est. completion 2019-01
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT02924064

    Efficacy and Safety of Teneligliptin in Combination With Metformin in Chinese Patients With Type 2 Diabetes Mellitus

    Not yet reported Tanabe Pharma Corporation 247 participants 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02926950

    Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus on Background of Metformin

    Not yet reported Lexicon Pharmaceuticals 518 participants Est. completion 2019-03-22 93 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02931253

    Metformin as an Upstream Therapy in Atrial Fibrillation

    Not yet reported The Guthrie Clinic 6 participants Est. completion 2018-07-10 1 site Stand-alone
    Other conditions: Atrial Fibrillation
    View official trial listing →
  • Status unknown NCT NCT02931591

    Effect of Insulin Sensitization on IGF-1 Response to Growth Hormone in SGA Children

    Not yet reported Cambridge University Hospitals NHS Foundation Trust 24 participants Est. completion 2020-06
    Other conditions: Small for Gestational Age
    View official trial listing →
  • Terminated NCT NCT02932475

    Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD)

    Not yet reported University of North Carolina, Chapel Hill 831 participants Est. completion 2022-06-15 10 sites
    Other conditions: Diabetes, Pregnancy
    View official trial listing →
  • Completed NCT NCT02941367

    Safety Assessment of Lyxumia (Lixisenatide) and Sulfonylurea as Add-on Treatment to Basal Insulin in Uncontrolled Patients With Type 2 Diabetes Mellitus Who Elect to Fast During Ramadan

    Not yet reported Sanofi 184 participants Est. completion 2017-08-04 16 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02941445

    Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss

    Not yet reported University Medical Centre Ljubljana 24 participants Est. completion 2016-08 Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Body Weight
    View official trial listing →
  • Terminated NCT NCT02945813

    SAKK 08/15 - PROMET - Salvage Radiotherapy +/- Metformin for Patients With Prostate Cancer After Prostatectomy

    Not yet reported Swiss Cancer Institute 112 participants Est. completion 2022-02-28 27 sites Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT02946632

    Effectiveness & Tolerability of Novel, Initial Triple Combination Therapy vs Conventional Therapy in Type 2 Diabetes

    Not yet reported Korea University Anam Hospital 104 participants Est. completion 2019-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Terminated NCT NCT02946996

    Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy

    Not yet reported Medical University of South Carolina 41 participants Est. completion 2024-08-19 1 site Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT02947620

    Metformin/Atorvastatin Combination Therapy in Subjects With Type II Diabetes and Dyslipidemia (Phase 3)

    Not yet reported Daewoong Pharmaceutical Co. LTD. 185 participants Est. completion 2017-02-27 1 site
    Other conditions: Type II Diabetes, Dyslipidemia
    View official trial listing →
  • Completed NCT NCT02948283

    Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia

    Not yet reported City of Hope Medical Center 3 participants Est. completion 2017-12-01 1 site Stand-alone
    Other conditions: Anemia, Fatigue, Fever, Lymphadenopathy, Lymphocytosis, Night Sweats, Recurrent Chronic Lymphocytic Leukemia, Recurrent Plasma Cell Myeloma, Refractory Chronic Lymphocytic Leukemia, Refractory Plasma Cell Myeloma, Splenomegaly, Thrombocytopenia, Weight Loss
    View official trial listing →
  • Completed NCT NCT02949193

    Efficacy and Safety of Evogliptin add-on to Metformin in Patients With type2 Diabetes

    Not yet reported Dong-A ST Co., Ltd. 222 participants Est. completion 2015-05 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02949700

    Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma

    Not yet reported, Not yet reported Baylor College of Medicine 26 participants Est. completion 2022-07-07 3 sites Stand-alone
    Other conditions: Head and Neck Squamous Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT02951260

    The Effects of Metformin on Self-selected Exercise Intensity, Physical Fitness and Exercise-induced AMPK-activation

    Not yet reported Rigshospitalet, Denmark 15 participants Est. completion 2017-07 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02954692

    A Study to Evaluate the Effectiveness and Safety Initiation and Titration of Insulin Glargine (U300) in Insulin-naïve Patients With Type 2 Diabetes Mellitus (T2DM) Controlled on Oral Antidiabetic Drug Treatment in Turkey

    Not yet reported Sanofi 112 participants Est. completion 2017-12-22 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02956044

    Interaction of Bexagliflozin With Metformin, Glimepiride and Sitagliptin

    Not yet reported Theracos 54 participants Est. completion 2017-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02960659

    Title: Therapeutic Targets in African-American Youth With Type 2 Diabetes

    Not yet reported, Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 24 participants Est. completion 2022-05-20 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02960711

    Metformin and Dietary Restriction to Prevent Age-related Morbid Events in People With Metabolic Syndrome

    Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 1600 participants Est. completion 2019-07 1 site Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT02964247

    LIRA-ADD2SGLT2i - Liraglutide Versus Placebo as add-on to SGLT2 Inhibitors.

    Not yet reported Novo Nordisk A/S 303 participants Est. completion 2018-05-08 82 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Terminated NCT NCT02967276

    Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma

    Not yet reported University of Campinas, Brazil 28 participants Est. completion 2020-02 2 sites Stand-alone
    Other conditions: Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT02972723

    Metformin Therapy in HCV Infection

    Not yet reported Nottingham University Hospitals NHS Trust 16 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Chronic Hepatitis C Infection
    View official trial listing →
  • Completed NCT NCT02973321

    A Study to Assess the Safety and Efficacy of SAR425899 in Patients With Type 2 Diabetes Mellitus

    Not yet reported Sanofi 296 participants Est. completion 2017-12-27 59 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02978547

    The Effects of Neoadjuvant Metformin on Tumour Cell Proliferation and Tumour Progression in Pancreatic Ductal Adenocarcinoma

    Not yet reported British Columbia Cancer Agency 20 participants Est. completion 2021-01 1 site Stand-alone
    Other conditions: Resectable Pancreatic Ductal Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT02980276

    RCT Metformin for Reduction of Gestational Diabetes Mellitus Effects

    Not yet reported National University of Ireland, Galway, Ireland 535 participants Est. completion 2023-04-13 2 sites
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Status unknown NCT NCT02981121

    Hospital-based Diabetes Prevention Study in Korea

    Not yet reported Jeong-taek Woo 744 participants Est. completion 2020-11 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT02981329

    Fetal Hemoglobin Induction Treatment Metformin

    Not yet reported Baylor College of Medicine 37 participants Est. completion 2020-07-20 2 sites Stand-alone
    Other conditions: Sickle Cell Anemia, Sickle Cell Disease, Hemoglobin Disorder
    View official trial listing →
  • Completed NCT NCT02982798

    The PK Characteristics of the Co-administration of Metformin SR and Rosuvastatin and JLP-1310 in Healthy Male Volunteers

    Not yet reported Jeil Pharmaceutical Co., Ltd. 40 participants Est. completion 2018-01-31 1 site Stand-alone
    Other conditions: Diabetes, Hyperlipidemia
    View official trial listing →
  • Status unknown NCT NCT02984475

    The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia Major

    Not yet reported Cairo University 60 participants Est. completion 2019-04 2 sites
    Other conditions: Beta Thalassemia Major Anemia
    View official trial listing →
  • Status unknown NCT NCT02984722

    Extended-release vs Immediate-release Metformin in PCOS Women

    Not yet reported Catholic University of the Sacred Heart 80 participants 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02986659

    Genomic Outcomes of Metformin

    Not yet reported Wake Forest University Health Sciences 30 participants Est. completion 2018-11-15 1 site
    Cardiovascular disease Other conditions: Mild Cognitive Impairment, Obesity, Abdominal, Hypertension
    View official trial listing →
  • Terminated NCT NCT02989649

    Non-Interventional Study of the Use of Alogliptin and Alogliptin Fixed-Dose Combinations With Pioglitazone and With Metformin in Standard Clinical Practice

    Takeda 593 participants Est. completion 2018-01-26 11 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT02990728

    Mirena® ± Metformin as Fertility-preserving Treatment for Young Asian Women With Early Endometrial Cancer

    Not yet reported Chang Gung Memorial Hospital 120 participants Est. completion 2020-03 Stand-alone
    Other conditions: Endometrial Cancer
    View official trial listing →
  • Completed NCT NCT03004612

    Effect of Linagliptin + Metformin vs Metformin Alone in Patients With Prediabetes

    Not yet reported Universidad de Guanajuato 144 participants Est. completion 2019-06 1 site Stand-alone
    Other conditions: Prediabetic State, Insulin Resistance
    View official trial listing →
  • Active, not recruiting NCT NCT03006172

    To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

    Not yet reported Genentech, Inc. 200 participants Est. completion 2026-12-31 12 sites Stand-alone
    Other conditions: Breast Cancer, Solid Tumor
    View official trial listing →
  • Completed NCT NCT03008551

    Empagliflozin vs Metformin in PCOS

    Not yet reported, Not yet reported Hull University Teaching Hospitals NHS Trust 40 participants Est. completion 2018-04-02 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT03010683

    Effects of Agonists of Glucagon Like Peptide - 1 Receptors (GLP-1R) on Arterial Stiffness, Endothelial Glycocalyx and Coronary Flow Reserve in Patients With Coronary Artery Disease and Patients With Diabetes Mellitus

    Not yet reported University of Athens 60 participants Est. completion 2017-12 1 site
    Type 2 diabetesCardiovascular disease
    View official trial listing →
  • Completed NCT NCT03017833

    Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers

    Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2022-12-21 1 site Stand-alone
    Other conditions: Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory Neoplasm
    View official trial listing →
  • Status unknown NCT NCT03018665

    A Study of the Effect of Glucagon-like Peptide 1(GLP-1) Receptor Agonist in Combination With Metformin Therapy on Diabetes Remission in Subjects With Newly Diagnosed Type 2 Diabetes Who Are Overweight or Obese

    Not yet reported The First Hospital of Jilin University 200 participants 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03029390

    Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes

    Not yet reported University of Guadalajara 28 participants Est. completion 2023-12 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Completed NCT NCT03029702

    Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus

    Not yet reported Maisa N. Feghali, MD 54 participants Est. completion 2023-08-31 1 site
    Other conditions: Gestational Diabetes, Diabetes, Gestational, Pregnancy in Diabetes
    View official trial listing →
  • Completed NCT NCT03030300

    Remission Rate of Newly Diagnosed Type 2 Diabetes Outpatients Treated With Short-term Intensive Insulin Therapy

    Not yet reported Qianfoshan Hospital 170 participants Est. completion 2015-02 3 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03031821

    Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome

    Not yet reported Canadian Urologic Oncology Group 166 participants Est. completion 2023-11-24 16 sites Stand-alone
    Metabolic syndrome Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT03034941

    Short Term Weight Loss With Liraglutide and Metformin in Infertile Obese PCOS Patients

    Not yet reported University Medical Centre Ljubljana 35 participants Est. completion 2016-12 1 site
    Other conditions: Obesity, PCOS
    View official trial listing →
  • Completed NCT NCT03038789

    XIGDUO Extended Release (XR) Post Marketing Surveillance

    AstraZeneca 623 participants Est. completion 2019-08-30 8 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03039075

    Metformin SR Tablet (DuLeNing) and Glucophage in Patients With Type 2 Diabetes

    Not yet reported Chongqing Medical University 240 participants Est. completion 2018-11 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03041129

    Post-Prandial Liver Glucose Metabolism in PCOS

    University of Colorado, Denver 19 participants Est. completion 2018-09-29 1 site
    Other conditions: Polycystic Ovarian Syndrome, Obesity, Hepatic Steatosis
    View official trial listing →
  • Terminated NCT NCT03047837

    A Randomized, 2x2 Factorial Design Biomarker Prevention Trial of Low-dose ASA and Metformin in Stage I-III Crc Patients

    Not yet reported Ente Ospedaliero Ospedali Galliera 160 participants Est. completion 2024-03-31 1 site Stand-alone
    Other conditions: Tertiary Prevention in Colon Cancer
    View official trial listing →
  • Status unknown NCT NCT03048500

    Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

    Not yet reported Northwestern University 17 participants Est. completion 2021-09 2 sites Stand-alone
    Other conditions: Recurrent Non-Small Cell Lung Carcinoma, Stage III Non-Small Cell Lung Cancer, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung Cancer, Stage IV Non-Small Cell Lung Cancer
    View official trial listing →
  • Completed NCT NCT03049228

    In and ex Vivo Mitochondrial Function of the Heart

    Maastricht University Medical Center 38 participants Est. completion 2020-03-02 1 site
    Type 2 diabetes Other conditions: Diabetic Cardiomyopathies
    View official trial listing →
  • Completed NCT NCT03050619

    Characteristics of Empagliflozin Initiators

    Boehringer Ingelheim 31908 participants Est. completion 2016-10-14 1 site
    Type 2 diabetes
    View official trial listing →
  • Suspended NCT NCT03051451

    Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity

    Not yet reported Laboratorios Silanes S.A. de C.V. 150 participants Est. completion 2018-11 1 site
    Other conditions: Overweight and Obesity
    View official trial listing →
  • Terminated NCT NCT03053518

    Validation of Machine Learning Based Personalized Nutrition Algorithm to Reduce Postprandial Glycemic Excursions Among North American Individuals With Newly Diagnosed Type 2 Diabetes

    Not yet reported NYU Langone Health 22 participants Est. completion 2018-01-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03054519

    Improve PAD PERformance With METformin

    Not yet reported Northwestern University 202 participants Est. completion 2025-11-01 5 sites
    Other conditions: Peripheral Artery Disease
    View official trial listing →
  • Status unknown NCT NCT03056274

    Metformin in Intrahepatic Cholestasis of Pregnancy

    Not yet reported, Not yet reported Epsom and St Helier University Hospitals NHS Trust 40 participants Est. completion 2019-09
    Other conditions: Intrahepatic Cholestases, Pregnancy Complications
    View official trial listing →
  • Terminated NCT NCT03060980

    Comparison of Efficacy, Safety, and Tolerability of ITCA 650 to Empagliflozin and Glimepiride as add-on Metformin

    Not yet reported Intarcia Therapeutics 245 participants Est. completion 2018-01-26 101 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03061214

    Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT)

    Not yet reported Novo Nordisk A/S 868 participants Est. completion 2019-04-15 67 sites
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT03061981

    A Study To Evaluate The Safety,Tolerability, PK and PD Of DA-1241 In Healthy Male Subjects

    Not yet reported Dong-A ST Co., Ltd. 60 participants Est. completion 2017-10-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03066830

    Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus on Background of Sulfonylurea Alone or With Metformin

    Not yet reported Lexicon Pharmaceuticals 507 participants Est. completion 2019-04-30 76 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03068065

    Antidiabetic Effects on Intrahepatic Fat

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 87 participants Est. completion 2015-10 1 site
    Type 2 diabetes Other conditions: Non-Alcoholic Fatty Liver Disease
    View official trial listing →
  • Status unknown NCT NCT03071705

    Metformin Plus TKI Use in Patients With Non-Small Cell Lung Carcinoma

    Not yet reported Instituto Nacional de Cancerologia de Mexico 120 participants Est. completion 2017-12 1 site Stand-alone
    Other conditions: Non-Small Cell Adenocarcinoma, Tyrosine Kinase Mutation, EGFR Gene Mutation
    View official trial listing →
  • Completed NCT NCT03072485

    Phase 1 Study of the Effects of Combining Topical FDA-approved Drugs on Age-related Pathways on the Skin of Healthy Volunteers

    Not yet reported Anne Chang 10 participants Est. completion 2019-02-22 1 site
    Other conditions: Aging
    View official trial listing →
  • Completed NCT NCT03076112

    Efficacy of Ipragliflozin Compared With Sitagliptin in Uncontrolled Type 2 Diabetes With Sulfonylurea and Metformin

    Not yet reported Seoul National University Bundang Hospital 170 participants Est. completion 2022-08-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03076281

    Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 7 participants Est. completion 2018-12-03 1 site Stand-alone
    Other conditions: Larynx, LIP, Oral Cavity, Pharynx
    View official trial listing →
  • Withdrawn NCT NCT03078725

    Failure Rate of GLyburide And Metformin Among Gestational Diabetics

    Not yet reported The University of Texas Health Science Center, Houston Est. completion 2018-05-10
    Other conditions: Gestational Diabetes Mellitus, Class A2
    View official trial listing →
  • Completed NCT NCT03086005

    Study to Assess the Effect of Metformin Supplementation on IVF Outcome in Patients With Polycystic Ovarian Syndrome.

    Not yet reported Chung-Hoon Kim 24 participants Est. completion 2015-07-23 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT03088631

    Metformin in Intracytoplasmic Sperm Injection Cycles

    Not yet reported Assiut University 320 participants Est. completion 2019-04-01 1 site
    Other conditions: Intracytoplasmatic Sperm Injection
    View official trial listing →
  • Completed NCT NCT03088670

    Efficacy and Safety of Gosogliptin as Monotherapy and in Combination With Metformin vs. Vildagliptin as Monotherapy and in Combination With Metformin in Drug-naive Type 2 Diabetic Patients.

    Not yet reported SatRx LLC 299 participants Est. completion 2014-10-03 27 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03098654

    Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care in Kisarawe, Tanzania

    Not yet reported Medical University of South Carolina 214 participants Est. completion 2022-08-05 1 site
    Type 2 diabetes Other conditions: Human Immunodeficiency Virus, Hypertension
    View official trial listing →
  • Completed NCT NCT03106870

    Adding Metformin to Insulin in Controlling Pregestational and Gestational Diabetes Mellitus

    Not yet reported Ain Shams University 62 participants Est. completion 2016-12
    Other conditions: Gestational Diabetes Mellitus in Pregnancy
    View official trial listing →
  • Active, not recruiting NCT NCT03107884

    Role of Metformin on Muscle Health of Older Adults

    Not yet reported University of Utah 64 participants Est. completion 2026-11-01 1 site Stand-alone
    Other conditions: Muscle Atrophy, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT03108963

    L-carnitine and Metformin in Obese PCOS Women.

    Not yet reported Zagazig University 280 participants Est. completion 2018-03 1 site Stand-alone
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT03109873

    Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 9 participants Est. completion 2020-07-31 1 site Stand-alone
    Other conditions: Larynx, Lip, Oral Cavity, Pharynx
    View official trial listing →
  • Completed NCT NCT03115112

    Safety and Efficacy of Bexagliflozin Compared to Sitagliptin as Add-on Therapy to Metformin in Type 2 Diabetes Subjects

    Not yet reported Theracos 386 participants Est. completion 2018-10-31 56 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03117517

    Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome

    Not yet reported Khyber Medical University Peshawar 106 participants Est. completion 2018-03-07 1 site Stand-alone
    Other conditions: Polycystic Ovarian Syndrome
    View official trial listing →
  • Terminated NCT NCT03118713

    A Study to Evaluate the Renal Protective Effect (Urine Albumin-to-Creatinine Ratio (UACR)), Efficacy and Safety of Ipragliflozin in Type 2 Diabetes Mellitus Patients With Albuminuria

    Not yet reported Astellas Pharma Korea, Inc. 33 participants Est. completion 2018-12-12 8 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03122041

    Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type 2 Diabetes in Metformin Intolerant Obese Women With Polycystic Ovary Syndrome

    Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2016-11
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT03122769

    Cardiac Uptake of Metformin, Visualized by Positron Emission Tomography

    Not yet reported Henrik Wiggers 6 participants Est. completion 2018-04-10 1 site Stand-alone
    Heart failure
    View official trial listing →
  • Completed NCT NCT03125694

    Sitagliptin vs. Pioglitazone as add-on Treatments in Patients With Type 2 Diabetes Uncontrolled on the Full-dose Metformin Plus Sulfonylurea

    Not yet reported Tehran University of Medical Sciences 250 participants Est. completion 2017-04-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03129113

    Adding MAraViroc &/or METformin for Hepatic Steatosis in People Living With HIV

    Not yet reported, Not yet reported University College, London 90 participants Est. completion 2020-11-06 6 sites Stand-alone
    Other conditions: Hepatic Steatosis, HIV-1-infection
    View official trial listing →
  • Completed NCT NCT03130426

    Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IGlarLixi

    Not yet reported Population Health Research Institute 161 participants Est. completion 2020-09-30 8 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03135301

    Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome

    Not yet reported Assiut University 80 participants Est. completion 2024-03 1 site Stand-alone
    Other conditions: Infertility, Female
    View official trial listing →
  • Completed NCT NCT03136484

    Efficacy and Safety of Semaglutide Versus Canagliflozin as add-on to Metformin in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 788 participants Est. completion 2018-11-16 119 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT03137186

    Repurposing Metformin as Anticancer Drug: in Advanced Prostate Cancer

    Not yet reported Mansoura University 120 participants Est. completion 2020-01 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT03138356

    Bioequivalence Study of Combination Tablets of Saxagliptin / Dapagliflozin / Metformin XR (Extended-release) and Dapagliflozin / Metformin XR Relative to Individual Components in Healthy Subjects

    Not yet reported AstraZeneca 126 participants Est. completion 2017-11-28 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03141073

    Long-term Efficacy and Safety of HMS5552 add-on to Metformin in T2DM Subjects

    Not yet reported Hua Medicine Limited 767 participants Est. completion 2021-02-28 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03151005

    The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS

    Not yet reported Xinqiao Hospital of Chongqing 70 participants Est. completion 2021-04-23 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome (PCOS), Overweight, Obesity
    View official trial listing →
  • Terminated NCT NCT03151772

    Bioavailability of Disulfiram and Metformin in Glioblastomas

    Not yet reported Sahlgrenska University Hospital 3 participants Est. completion 2020-09-24 1 site Stand-alone
    Other conditions: Glioblastoma
    View official trial listing →
  • Completed NCT NCT03165877

    Effect of Low-glycemic Index Meals Intake on DM2 Women Under Metformin Therapy

    Not yet reported Universidad de Valparaiso 13 participants Est. completion 2016-10-13
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03167918

    Lung Function in Patients With Early Type 2 Diabetes Mellitus

    Not yet reported, Not yet reported Liaoning University of Traditional Chinese Medicine 200 participants Est. completion 2017-05-01 Stand-alone
    Type 2 diabetes Other conditions: Pulmonary Function
    View official trial listing →
  • Completed NCT NCT03169959

    A Study to Evaluate the Food Effect on Drug Availability, Pharmacokinetic (PK) Properties, Safety and Tolerability of Two Different Dose Combination Therapy of Saxagliptin/Dapagliflozin/Metformin Extended-release (XR) Against Individual Component Co-administration.

    Not yet reported AstraZeneca 85 participants Est. completion 2017-08-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03172494

    A Trial Comparing Insulin Degludec/Liraglutide, Insulin Degludec, and Liraglutide in Chinese Subjects With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs (OADs)

    Not yet reported Novo Nordisk A/S 720 participants Est. completion 2019-07-13 36 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT03175120

    A Trial Comparing Insulin Degludec/Liraglutide and Insulin Degludec in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Therapy and Metformin With or Without One Other Oral Antidiabetic Drug (OAD)

    Not yet reported Novo Nordisk A/S 453 participants Est. completion 2019-04-04 37 sites Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT03179254

    Type 2 Diabetes and Ambulatory Surgery Patients

    Not yet reported University of Texas Southwestern Medical Center 160 participants Est. completion 2014-08-26 Stand-alone
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT03183752

    Insulin Resistance and Metformin Use on Volume of Benign Thyroid Nodules

    Not yet reported Hospital Universitário Clementino Fraga Filho 28 participants Est. completion 2019-04-17 1 site Stand-alone
    Other conditions: Thyroid Nodule, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT03184493

    Celebrex and Metformin for Postoperative Hepatocellular Carcinoma

    Not yet reported Guangxi Medical University 200 participants Est. completion 2021-06 1 site Stand-alone
    Other conditions: Liver Cancer
    View official trial listing →
  • Completed NCT NCT03189407

    Effect of Moringa Oleifera on Metformin Plasma Level in Type 2 Diabetes Mellitus Patients

    Not yet reported Titilayo O Fakeye 25 participants Est. completion 2016-04-30
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03189732

    Effect of Metformin on Exercise-induced Lipolysis

    Not yet reported Charles University, Czech Republic 10 participants Est. completion 2018-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03192293

    Metformin and Simvastatin in Addition to Fulvestrant

    Not yet reported National University Hospital, Singapore 28 participants Est. completion 2019-01-20 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT03194009

    PRuDENTE; Diabetes Prevention Via Exercise, Nutrition and Treatment

    Not yet reported Instituto Nacional de Salud Publica, Mexico 3060 participants Est. completion 2022-12-31 1 site
    Type 2 diabetes Other conditions: Prediabetic State
    View official trial listing →
  • Completed NCT NCT03194945

    Effects of Sequential Treatment Based on Lina/MET After Short-term Intensive Insulin in Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 412 participants Est. completion 2022-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03196154

    Association Between Insulin Resistance and Beta Cell Function With HbA1C in Diabetics

    Clinical Research Centre, Malaysia 255 participants Est. completion 2018-03-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03196362

    Impacts of PIO/MET Following Short-term Intensive Insulin Treatment in Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 50 participants Est. completion 2018-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03200015

    Rituximab, Cyclophosphamide, Vincristine and Prednisone (R-CHOP) Plus Metformin in Diffuse Large-B-cell Lymphoma

    Not yet reported Hospital Universitario Dr. Jose E. Gonzalez 15 participants Est. completion 2019-01-27 1 site Stand-alone
    Other conditions: Diffuse Large B Cell Lymphoma
    View official trial listing →
  • Completed NCT NCT03202563

    Trial to Evaluate the Efficacy on Glycemic Variability and Safety of Gemigliptin Compared With Dapagliflozin Added on Metformin Alone or Diabetes Medication Naïve Patient in Type 2 Diabetes Mellitus (Stable II Study)

    Not yet reported LG Chem 71 participants Est. completion 2018-12-07 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03204058

    Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 90 participants Est. completion 2017-02-23
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Completed NCT NCT03204071

    Locally Delivered Metformin and Aloe Vera for Treatment of Intrabody Defects in Chronic Periodontitis

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 90 participants Est. completion 2017-02
    Other conditions: Chronic Periodontitis
    View official trial listing →
  • Status unknown NCT NCT03204799

    Metagenomic Analysis of Human Gut Microbiota in Patients With Metabolic Diseases Including Diabetes

    Yonsei University 150 participants Est. completion 2019-12-16 1 site
    Type 2 diabetes Other conditions: Dyslipidemias
    View official trial listing →
  • Completed NCT NCT03207698

    PRF+1% MF for Class II Mandibular Furcation Defects

    Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 75 participants Est. completion 2016-05 1 site
    Other conditions: Furcation Defects
    View official trial listing →
  • Completed NCT NCT03208309

    Effect of Diacerein in the Metabolic Control of Patients With DM Type 2 and Secondary Failure to Metformin

    Not yet reported ANS Pharma 40 participants Est. completion 2015-12 3 sites
    Type 2 diabetes Other conditions: Complications of Diabetes Mellitus, Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03214380

    A Study of LY900014 Compared to Insulin Lispro in Participants With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 933 participants Est. completion 2019-03-13 141 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03216278

    The Purpose of the Study is to Compare Two Fixed Dose Combination Tablets of Dapagliflozin/Metformin XR in Healthy Subjects Under Fasting and Fed Conditions

    Not yet reported AstraZeneca 284 participants Est. completion 2018-05-22 1 site Stand-alone
    Other conditions: Healthy Subjects in Fasted and Fed State
    View official trial listing →
  • Status unknown NCT NCT03222765

    Prevention of Microvascular Complications in Prediabetes e-PREDICE Study

    Not yet reported Evidem Consultores SL 1000 participants Est. completion 2019-12-31 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Completed NCT NCT03225209

    Medically Reproducing Bariatric Surgery

    Not yet reported Moahad S Dar 5 participants Est. completion 2018-10-23 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03229057

    Comparing the Effects of Oral Contraceptive Pills Versus Metformin

    Not yet reported Anuja Dokras 240 participants Est. completion 2024-07-15 2 sites Stand-alone
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT03230786

    Study to Evaluate the Efficacy and Safety of KBP-042 in Patients With Type 2 Diabetes

    Not yet reported KeyBioscience AG 255 participants Est. completion 2018-07-31 30 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03235050

    A Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes

    Not yet reported AstraZeneca 834 participants Est. completion 2019-06-14 119 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03236740

    OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS

    Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2018-03-15 1 site
    Other conditions: PCOS
    View official trial listing →
  • Status unknown NCT NCT03238495

    Randomized Trial of Neo-adjuvant Chemotherapy With or Without Metformin for HER2 Positive Operable Breast Cancer

    Not yet reported Qamar Khan 100 participants Est. completion 2023-06-01 6 sites Stand-alone
    Other conditions: HER2-positive Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT03239119

    The Effectivity and Safety Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 456 participants Est. completion 2019-01-15
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03243851

    Study on Low Dose Temozolomide Plus Metformin or Placebo in Patient With Recurrent or Refractory Glioblastoma

    Not yet reported Yong-Kil Hong 81 participants Est. completion 2020-12-31 12 sites Stand-alone
    Other conditions: Glioblastoma
    View official trial listing →
  • Completed NCT NCT03246451

    The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D

    Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2017-12-10 1 site Stand-alone
    Other conditions: Glucose Metabolism Disorders
    View official trial listing →
  • Completed NCT NCT03249506

    Cardiovascular Outcomes in Participants With Type 2 Diabetes Mellitus (T2DM)

    Janssen Research & Development, LLC 25358 participants Est. completion 2017-11-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03249896

    Web/Smartphone-based Lifestyle Coaching Program in Pregnant Women With Gestational Diabetes

    Not yet reported National University Hospital, Singapore 340 participants Est. completion 2019-05 1 site
    Other conditions: Gestational Diabetes, Pregnancy Complications, Weight Gain
    View official trial listing →
  • Completed NCT NCT03253562

    Metformin Versus Vildagliptin for Diabetic Hypertensive Patients

    Not yet reported MTI University 120 participants Est. completion 2017-08-01 1 site
    Other conditions: Reducing the Elevated Blood Pressure for Diabetic Hypertensive Patients
    View official trial listing →
  • Terminated NCT NCT03258723

    Diabetes Prevention With Lifestyle Intervention and Metformin Escalation

    Not yet reported Yale University 114 participants Est. completion 2021-12-01 4 sites Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT03259490

    This Study Tests Whether Taking the Medicines Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills. The Study is Done in Healthy Men and Women and Measures the Amount of Each Medicine in the Blood

    Not yet reported Boehringer Ingelheim 30 participants Est. completion 2017-11-13 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03259789

    Safety and Efficacy of Bexagliflozin Compared to Placebo as Add-on Therapy to Metformin in Type 2 Diabetes Subjects

    Not yet reported Theracos 351 participants Est. completion 2019-01-23 43 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03259919

    Metformin Treatment of Pregnant Women With Polycystic Ovary Syndrome: a Pilot Study

    Not yet reported Norwegian University of Science and Technology 40 participants Est. completion 2003-03 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT03267576

    An Efficacy Study of Canagliflozin or Sitagliptin to Determine Glucose Variability in Mexican Participants With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin

    Not yet reported Janssen Research & Development, LLC 64 participants Est. completion 2018-10-01 5 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03268005

    Research Study Comparing a New Medicine "Fast-acting Insulin Aspart" to Another Already Available Medicine "NovoRapid"/"NovoLog" in People With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 1264 participants Est. completion 2019-01-29 167 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT03271866

    Metformin Treatment on Cognitive Impairment of Schizophrenia Co-morbid Metabolic Syndrome

    Not yet reported Central South University 80 participants Est. completion 2023-12-31 1 site
    Other conditions: Schizophrenia
    View official trial listing →
  • Status unknown NCT NCT03279263

    An Add-on Study of MLR-1023 in Adults With Uncontrolled Type 2 Diabetes on Metformin Therapy

    Not yet reported Melior Pharmaceuticals 400 participants Est. completion 2019-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03283657

    Diabetes Risk Education and Communication Trial

    Not yet reported Northwestern University 53 participants Est. completion 2019-03-17 1 site Stand-alone
    PrediabetesType 2 diabetes Other conditions: Diabetes Mellitus, Body Weight, Body Weight Changes
    View official trial listing →
  • Completed NCT NCT03297879

    Comparison of Exenatide and Metformin Monotherapy in Overweight/Obese Patients With Newly Diagnosed Type 2 Diabetes

    Not yet reported Beijing Chao Yang Hospital 230 participants Est. completion 2016-02-28 Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03307252

    This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy Men

    Not yet reported Boehringer Ingelheim 45 participants Est. completion 2018-05-02 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03309007

    A Double-Blind, Placebo-Controlled Trial of Anti-Aging, Pro-Autophagy Effects of Metformin in Adults With Prediabetes

    Not yet reported University of New Mexico 25 participants Est. completion 2020-08-20 1 site Stand-alone
    Prediabetes Other conditions: Aging
    View official trial listing →
  • Completed NCT NCT03310749

    An Assessment of Pharmacokinetic Gemigliptin and Metformin Interactions in Healthy Mexican Volunteers

    Not yet reported Stendhal Americas, S.A. 34 participants Est. completion 2016-05-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT03311308

    A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma

    Not yet reported Yana Najjar 23 participants Est. completion 2029-12-31 1 site Stand-alone
    Other conditions: Advanced Melanoma
    View official trial listing →
  • Completed NCT NCT03312582

    Locally Delivered 1% Metformin Gel in Peri-implantitis

    Not yet reported King Saud University 46 participants Est. completion 2017-07-24 Stand-alone
    Other conditions: Peri-Implantitis
    View official trial listing →
  • Completed NCT NCT03316690

    The Interaction Between Metformin and Physical Training

    Not yet reported Kristian Karstoft 34 participants Est. completion 2018-10-01 1 site Stand-alone
    PrediabetesType 2 diabetes
    View official trial listing →
  • Completed NCT NCT03317028

    CS02 vs Placebo With Metformin in Type 2 Diabetes Mellitus (T2DM)

    Not yet reported Center Laboratories, Inc. 201 participants Est. completion 2020-04-21 13 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03320694

    Comparison of Metformin and Insulin for Management of Gestational Diabetes Mellitus

    Not yet reported Services Institute of Medical Sciences, Pakistan 278 participants Est. completion 2017-06-30 1 site Stand-alone
    Other conditions: Gestational Diabetes Mellitus in Pregnancy
    View official trial listing →
  • Completed NCT NCT03323294

    Bioenergetics and Metabolism in Pediatric Populations

    Arkansas Children's Hospital Research Institute 79 participants Est. completion 2024-06-30 1 site
    Type 2 diabetes Other conditions: Obesity, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT03329651

    The Interaction Between Metformin and Acute Exercise

    Not yet reported Kristian Karstoft 34 participants Est. completion 2018-10-01 1 site Stand-alone
    PrediabetesType 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03331861

    Metformin in Heart Failure Without Diabetes

    Not yet reported Columbia University 6 participants Est. completion 2021-08-20 1 site Stand-alone
    Heart failure
    View official trial listing →
  • Completed NCT NCT03332771

    Efficacy and Safety of Sotagliflozin Versus Glimepiride and Placebo in Participants With Type 2 Diabetes Mellitus That Are Taking Metformin Monotherapy

    Not yet reported Lexicon Pharmaceuticals 954 participants Est. completion 2019-09-06 142 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03335423

    Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug Interactions

    Not yet reported University of Southern Denmark 228 participants Est. completion 2020-06-13 1 site Stand-alone
    Other conditions: Metformin, Organic Cation Transporter 1, Codeine
    View official trial listing →
  • Status unknown NCT NCT03336840

    Effect of Metformin and Probiotics in Reproductive-aged Patients With Polycystic Ovary Syndrome

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 90 participants Est. completion 2019-06 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT03349684

    Loose-dose Combination of Acarbose and Metformin for T2DM in Metformin-failure Patients

    Not yet reported Bayer 287 participants Est. completion 2019-08-21 29 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03349775

    Cardiometabolic Disease and Pulmonary Hypertension

    Not yet reported Massachusetts General Hospital 21 participants Est. completion 2020-12-22 1 site
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT03351478

    Efficacy and Safety of Sotagliflozin Versus Placebo and Empagliflozin in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking a DPP4 Inhibitor Alone or With Metformin

    Not yet reported Lexicon Pharmaceuticals 770 participants Est. completion 2019-05-16 160 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03352869

    Research of Exenatide for Overweight/Obese PCOS Patients With IGR

    Not yet reported RenJi Hospital 183 participants Est. completion 2018-07-31 1 site Added to GLP-1
    Other conditions: Polycystic Ovary Syndrome, Overweight and Obesity, Disorder of Glucose Regulation
    View official trial listing →
  • Completed NCT NCT03353948

    The Effect of a Liraglutide on IVF in Obese PCOS

    Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2016-09-01
    Other conditions: Polycystic Ovary Syndrome, Obesity, Infertility, Female
    View official trial listing →
  • Completed NCT NCT03355014

    BE Study of the Combinations of Gemigliptin/Metformin HCl Extended Release 50/1000mg(25/500mg x 2 Tablets) in Comparison to Each Component Administered Alone

    Not yet reported LG Chem 70 participants Est. completion 2018-01-12 1 site Stand-alone
    Other conditions: Healthy Male Volunteers
    View official trial listing →
  • Completed NCT NCT03355469

    Exercise Dose and Metformin for Vascular Health in Metabolic Syndrome

    Not yet reported, Not yet reported Rutgers University 91 participants Est. completion 2024-05-23 1 site
    Metabolic syndrome
    View official trial listing →
  • Completed NCT NCT03359590

    Sitagliptin and the Risk for Hypoglycaemia in Type 2 Diabetes Patients

    Not yet reported Profil Institut für Stoffwechselforschung GmbH 20 participants Est. completion 2019-07-17 1 site
    Other conditions: Pharmacological Action
    View official trial listing →
  • Completed NCT NCT03359681

    Metformin Treatment for Colon Cancer

    Not yet reported Zealand University Hospital 48 participants Est. completion 2021-10-04 1 site
    Other conditions: Colon Cancer
    View official trial listing →
  • Completed NCT NCT03359837

    Comparison of Two Treatment Regimens in Patients With Type 2 Diabetes After Short-term Intensive Insulin Therapy

    Not yet reported Sanofi 384 participants Est. completion 2020-06-29 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03361878

    Pharmacokinetics of Metformin Intolerance

    Not yet reported NHS Tayside 20 participants Est. completion 2016-05-05
    Type 2 diabetes Other conditions: Metformin Adverse Reaction
    View official trial listing →
  • Completed NCT NCT03363815

    A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult Subjects

    Not yet reported Celgene 56 participants Est. completion 2018-07-29 1 site Stand-alone
    Other conditions: Heathy Volunteer
    View official trial listing →
  • Completed NCT NCT03364335

    The Effect Of NS-0200 and NS-0300 Versus Placebo on Weight In Obesity

    Not yet reported NuSirt Biopharma 267 participants Est. completion 2018-08-17 15 sites
    Other conditions: Obesity
    View official trial listing →
  • Status unknown NCT NCT03375580

    Therapeutic Effects of Compound Zhenzhu Tiaozhi Capsules in NAFLD

    Not yet reported The First Affiliated Hospital of Guangdong Pharmaceutical University 196 participants Est. completion 2019-12-31 1 site
    MASLD
    View official trial listing →
  • Status unknown NCT NCT03377335

    Dapagliflozin, Cardio-Metabolic Risk Factors and Type-2 Diabetes

    Not yet reported University of Palermo 186 participants Est. completion 2019-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03378297

    IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC

    Not yet reported Haukeland University Hospital 26 participants Est. completion 2023-01-05 2 sites Stand-alone
    Other conditions: Ovarian Cancer
    View official trial listing →
  • Terminated NCT NCT03380091

    Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial

    Not yet reported University of California, San Francisco 5 participants Est. completion 2019-09-01 1 site Stand-alone
    Other conditions: PCOS, Depression, Vitamin D Deficiency, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT03383068

    Research of Intensive Metabolic Intervention Before Pregnancy in PCOS

    Not yet reported RenJi Hospital 160 participants Est. completion 2020-06-30 1 site Mixed
    Prediabetes Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT03393208

    Glucophage Immediate Release (GIR) China Bioequivalence Study

    Not yet reported Merck KGaA, Darmstadt, Germany 44 participants Est. completion 2018-01-29 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03398356

    Metformin and Its Impact on the Substances Associated With NO Production in Prediabetes Patients.

    Not yet reported Wroclaw Medical University 47 participants Est. completion 2019-04-30 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT03398824

    Pilot Study of Metformin for Patients With Fanconi Anemia

    Not yet reported Boston Children's Hospital 15 participants Est. completion 2020-10-09 1 site Stand-alone
    Other conditions: Fanconi Anemia
    View official trial listing →
  • Completed NCT NCT03416127

    Effect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes Mellitus

    Not yet reported University of Guadalajara 36 participants Est. completion 2019-12-20 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03419624

    The Potential of Dapagliflozin Plus Exenatide in Obese Insulin-resistant Patients

    Not yet reported Universitätsklinikum Hamburg-Eppendorf 13 participants Est. completion 2019-08-05 4 sites Added to GLP-1
    Type 2 diabetes Other conditions: Obesity
    View official trial listing →
  • Status unknown NCT NCT03421119

    Comparing Efficacy and Safety of CinnaGen-liraglutide Versus Victoza® in Patients With Type II Diabetes

    Not yet reported Cinnagen 300 participants Est. completion 2019-12-01 Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03429543

    Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

    Not yet reported Boehringer Ingelheim 175 participants Est. completion 2023-05-31 83 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03430856

    Comparison of Insulin Tregopil (IN-105) With Insulin Aspart in Type 2 Diabetes Mellitus Patients

    Not yet reported, Not yet reported Biocon Limited 143 participants Est. completion 2019-02-20 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03441750

    Efficacy of Metformin in Preventing Diabetes in China

    Not yet reported Chinese Association of Geriatric Research 1724 participants Est. completion 2021-06-30 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Completed NCT NCT03444584

    Study of MEDI0382 in Combination With Dapagliflozin and Metformin in Overweight/Obese Participants With Type 2 Diabetes

    Not yet reported MedImmune LLC 49 participants Est. completion 2018-12-06 8 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03445702

    Metformin Gastrointestinal Intolerance: Measurement of Mitochondrial Complex I

    Not yet reported St. Louis University 15 participants Est. completion 2020-10-27 1 site Stand-alone
    Type 2 diabetes Other conditions: Metformin Adverse Reaction
    View official trial listing →
  • Terminated NCT NCT03451006

    Effect of Metformin on Frailty in 12 Subjects

    Not yet reported Mayo Clinic 7 participants Est. completion 2021-12-16 1 site Stand-alone
    Other conditions: Aging, Inflammation, Frailty
    View official trial listing →
  • Completed NCT NCT03451734

    Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients

    Central South University 2000 participants Est. completion 2021-06-30 1 site
    Metabolic syndrome Other conditions: Schizophrenia
    View official trial listing →
  • Withdrawn NCT NCT03452267

    Insulin Signaling in Skeletal Muscle

    Not yet reported, Not yet reported Wayne State University Est. completion 2025-06 Stand-alone
    Other conditions: Insulin Sensitivity
    View official trial listing →
  • Completed NCT NCT03452306

    Bioequivalence Study of Metformin 750 mg Tablets XR Versus Glucophage® Long 750 mg Tablets XR In Normal Healthy Subjects Under Fasting and Fed Conditions

    Not yet reported Geropharm 28 participants Est. completion 2017-07-22 1 site Stand-alone
    Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT03458208

    Bioequivalence Study of Metformin 1000 mg Tablets Immediate Release (IR) Versus Glucophage® 1000 mg Tablets IR In Healthy Subjects

    Not yet reported Geropharm 18 participants Est. completion 2017-03-02 1 site Stand-alone
    Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT03464045

    Empa PASS on Urinary Tract Malignancies

    Boehringer Ingelheim 344995 participants Est. completion 2024-03-11 3 sites
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT03465345

    Study of Metformin Plus Oligomeric Procyanidin Complex for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients

    Not yet reported Medical University of South Carolina Est. completion 2018-07-11 1 site Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT03467763

    Trial of an Intervention to Improve Metformin Persistence and Adherence

    Not yet reported Weill Medical College of Cornell University 13 participants Est. completion 2020-08-01 1 site
    Other conditions: Metformin Adverse Reaction, Tolerance
    View official trial listing →
  • Completed NCT NCT03467971

    A Study to Assess the Food Effect on Bioavailability of Metformin/Gliclazide in Healthy Participants

    Not yet reported Merck KGaA, Darmstadt, Germany 21 participants Est. completion 2018-04-22 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT03475524

    USE THE SYSTEMIC METFORMIN IN MELASMA

    Not yet reported Assiut University 60 participants Est. completion 2021-08 1 site Stand-alone
    Other conditions: Melasma
    View official trial listing →
  • Terminated NCT NCT03477162

    Metformin Pharmacology in Human Cancers: A Proof of Principle Study

    Not yet reported Dartmouth-Hitchcock Medical Center 18 participants Est. completion 2021-11-30 1 site Stand-alone
    Other conditions: Thoracic Neoplasm
    View official trial listing →
  • Completed NCT NCT03479476

    A Trial of Metformin in Individuals With Fragile X Syndrome

    Not yet reported, Not yet reported University of California, Davis 120 participants Est. completion 2024-05-22 3 sites
    Other conditions: Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome Disorders
    View official trial listing →
  • Status unknown NCT NCT03486626

    Endometrial Thickness and Subendometrial Vascularity in Anovulatory Polycystic Ovarian Syndrome Patients Treated by Metformin

    Not yet reported Ain Shams Maternity Hospital 85 participants Est. completion 2018-10 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Anovulatory
    View official trial listing →
  • Status unknown NCT NCT03489317

    Gut Microbiomes in Patients With Metabolic Syndrome

    Chinese University of Hong Kong 1000 participants Est. completion 2021-12 2 sites
    Metabolic syndrome
    View official trial listing →
  • Status unknown NCT NCT03489668

    Androgen Responses to hCG and Ovarian Morphology in PCOS

    Not yet reported Poznan University of Medical Sciences 100 participants Est. completion 2020-03-31 1 site
    Other conditions: PCOS
    View official trial listing →
  • Withdrawn NCT NCT03490019

    Treatment of Bardet-Biedl-Syndrome With Metformin for Evaluation of a Possible Visual Improvement

    Not yet reported University Hospital Tuebingen Est. completion 2020-08 Stand-alone
    Other conditions: Bardet-Biedl Syndrome, Visual Impairment
    View official trial listing →
  • Completed NCT NCT03491241

    Inflammatory Axis and Sirtuins' in Overweight Pre-diabetics Patients

    Not yet reported University of Campania Luigi Vanvitelli 60 participants Est. completion 2018-01-01 1 site
    Prediabetes Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT03495102

    A Study of the Efficacy and Safety of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 1842 participants Est. completion 2019-10-10 208 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03499704

    A Study to Evaluate the Effect of add-on Pioglitazone or Dapagliflozin in Participants With Type 2 Diabetes Mellitus Inadequately Controlled by DPP-4 Inhibitor and Metformin Therapy

    Not yet reported Celltrion Pharm, Inc. 133 participants Est. completion 2024-01-16 15 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03503942

    The Pre-Diabetes Interventions and Continued Tracking to Ease-out Diabetes (Pre-DICTED) Program

    Not yet reported Singapore General Hospital 751 participants Est. completion 2024-04-15 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT03507413

    Metformin Therapy in Non-diabetic AAA Patients

    Not yet reported, Not yet reported Medical University of Vienna 170 participants Est. completion 2024-05-01 1 site
    Other conditions: Abdominal Aortic Aneurysm
    View official trial listing →
  • Completed NCT NCT03510390

    Metformin in Head and Neck Squamous Cell Carcinoma: Effect on Tissue Oxygenation

    Not yet reported Insel Gruppe AG, University Hospital Bern 17 participants Est. completion 2021-11-15 1 site Stand-alone
    Other conditions: Head and Neck Cancer, Oral Cavity Squamous Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT03513874

    Metformin Plus Insulin on Non-obese Autoimmune Diabetes

    Not yet reported Second Xiangya Hospital of Central South University 15 participants Est. completion 2021-04-01 1 site Stand-alone
    Other conditions: Type 1 Diabetes Mellitus, Autoimmune Diabetes
    View official trial listing →
  • Completed NCT NCT03514108

    DANHEART (H-HeFT and Met-HeFT)

    Not yet reported Henrik Wiggers 1100 participants Est. completion 2025-12-31 26 sites
    Heart failure Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT03525028

    A Clinical Trial of Metformin to Decrease Glucocorticoids Side Effects in Patients With Autoimmune Uveitis

    Not yet reported Tianjin Medical University 138 participants Est. completion 2023-01-01 1 site Stand-alone
    Other conditions: Uveitis, Metformin, Glucocorticoid
    View official trial listing →
  • Completed NCT NCT03529123

    Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes (LixiLan-India)

    Not yet reported Sanofi 247 participants Est. completion 2019-11-25 13 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03538704

    Effect of Fertility-sparing Therapy of Early Endometrial Cancer

    Not yet reported Peking University People's Hospital 80 participants Est. completion 2020-12-31 1 site Stand-alone
    Other conditions: Endometrial Cancer, Fertility
    View official trial listing →
  • Completed NCT NCT03546062

    Diabetes and Lipid Accumulationand Heart Transplant

    University of Campania Luigi Vanvitelli 177 participants Est. completion 2018-05-01 2 sites
    Heart failure Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03552991

    Effects of Dietary Fiber on Glucose Control in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Samsung Medical Center 14 participants Est. completion 2018-05-31
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03555565

    Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"

    Takeda 1026 participants Est. completion 2019-10-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03558867

    Personalised Medicine in Pre-diabetes and Early Type 2 Diabetes

    Not yet reported Garvan Institute of Medical Research 138 participants Est. completion 2024-07-23 1 site
    Type 2 diabetes Other conditions: Pre Diabetes
    View official trial listing →
  • Completed NCT NCT03566225

    Pioglitazone Versus Metformin as First Treatment in Infertile Women With Polycystic Ovary Syndrome

    Not yet reported Ain Shams University 400 participants Est. completion 2021-03-30 1 site
    Other conditions: Pioglitazone
    View official trial listing →
  • Completed NCT NCT03566810

    Glucophage Extended Release (GXR) China Bioequivalence Study (Nantong - Darmstadt)

    Not yet reported Merck KGaA, Darmstadt, Germany 54 participants Est. completion 2018-11-28 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03570632

    Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus

    Not yet reported Maisa N. Feghali, MD 24 participants Est. completion 2026-05-31 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Type 1, Pregnancy in Diabetes
    View official trial listing →
  • Withdrawn NCT NCT03577184

    Evaluating the Glycemic Control wIth Vildagliptin and Metformin Combination Therapy.

    Clinision Est. completion 2019-03
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03583385

    Glucophage® Extended Release (XR) 750 Milligram (mg) Indonesia Bioequivalence (BE) Study

    Not yet reported Merck KGaA, Darmstadt, Germany 48 participants Est. completion 2018-10-05 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT03585777

    Compare Serum Klotho Levels in Patients on Oral Antidiabetic Treatment

    Fayoum University 90 participants Est. completion 2019-03 1 site
    Other conditions: Compare Serum Level of Klotho in Patients on Oral Antidiabetic Treatment
    View official trial listing →
  • Status unknown NCT NCT03590262

    Effect of Metformin as add-on Therapy on Glycemic Control and Other Outcomes in Type 1 Diabetes

    Not yet reported Shenzhen People's Hospital 20 participants Est. completion 2019-09-30 1 site Stand-alone
    Other conditions: Type 1 Diabetes Mellitus, Metformin
    View official trial listing →
  • Completed NCT NCT03593135

    Effect of Apple Cider Vinegar in Type 2 Diabetics

    Not yet reported Sheikh Zayed Federal Postgraduate Medical Institute 126 participants Est. completion 2017-11-14 1 site Stand-alone
    Other conditions: Randomized Controlled Trial, Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03593538

    Effects of Metformin During Nicotine Withdrawal

    Not yet reported University of Pennsylvania 80 participants Est. completion 2020-03-13 1 site Stand-alone
    Other conditions: Smoking, HIV-1-infection
    View official trial listing →
  • Completed NCT NCT03593707

    Drug-Drug Interaction Study to Evaluate the Effect of PF-06865571 on Metformin Pharmacokinetics

    Not yet reported Pfizer 18 participants Est. completion 2019-02-13 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT03596450

    Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial

    Not yet reported Novo Nordisk A/S 1278 participants Est. completion 2023-06-09 181 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03600363

    A Clinical Trial of Metformin in the Maintenance of Non-Hodgkin's Lymphoma Patients

    Not yet reported Ruijin Hospital 250 participants Est. completion 2021-12 1 site Stand-alone
    Other conditions: Lymphoma, Large B-Cell, Diffuse, Stage III Follicular Lymphoma
    View official trial listing →
  • Terminated NCT NCT03603080

    Efficacy of Pharmacotherapy to Enhance Weight Loss Following Sleeve Gastrectomy

    Not yet reported Hartford Hospital 12 participants Est. completion 2022-09-01 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Active, not recruiting NCT NCT03603912

    Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)

    Not yet reported Mina Chung, MD 175 participants Est. completion 2027-12 1 site Stand-alone
    Other conditions: Atrial Fibrillation
    View official trial listing →
  • Completed NCT NCT03604419

    Dose-finding of PB-119 Administered Subcutaneously Once Weekly Versus Placebo in Subjects With Type 2 Diabetes

    Not yet reported PegBio Co., Ltd. 214 participants Est. completion 2019-07-23 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03606694

    Effect of Dihydromirycetin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes Mellitus

    Not yet reported University of Guadalajara 24 participants Est. completion 2023-12-30 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT03608358

    Safety and Efficacy of Dapagliflozin in Asian T2DM Subjects With Inadequate Glycemic Control on Metformin/Saxagliptin

    Not yet reported AstraZeneca 41 participants Est. completion 2020-08-04 4 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03610412

    Cinnamomum Cassia Effect on IGF1 and Metabolic Control in Patients With DM2 Without Glycemic Control Metformin Treated

    Not yet reported Coordinación de Investigación en Salud, Mexico 28 participants Est. completion 2021-08-18 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03617458

    Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension

    Not yet reported Vanderbilt University Medical Center 73 participants Est. completion 2025-08-19 1 site
    Other conditions: Pulmonary Artery Hypertension
    View official trial listing →
  • Completed NCT NCT03618472

    Comparison of the Effectiveness Metformin for Deceasing Proliferative Marker in Endometrial Cancer Cells

    Not yet reported Department of Medical Services Ministry of Public Health of Thailand 50 participants Est. completion 2020-01-30 1 site Stand-alone
    Other conditions: Metformin, CA Endometrium
    View official trial listing →
  • Completed NCT NCT03618654

    Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma

    Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 38 participants Est. completion 2022-12-07 1 site Stand-alone
    Other conditions: Head and Neck Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma
    View official trial listing →
  • Status unknown NCT NCT03627039

    Metformin And Cardiovascular Effectiveness vs SGLT2 (MACES)

    Brigham and Women's Hospital 20000 participants Est. completion 2020-08-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03629054

    This Study in Healthy People Tests Whether Taking a Low Strength of Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills

    Not yet reported Boehringer Ingelheim 30 participants Est. completion 2018-11-05 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03629340

    Metformin for Pulmonary Hypertension HFpEF

    Not yet reported University of California, San Francisco 33 participants Est. completion 2026-02-27 2 sites Stand-alone
    Heart failure Other conditions: Pulmonary Hypertension
    View official trial listing →
  • Status unknown NCT NCT03629639

    Metformin for Treatment of Psoriasis Combined With Disorders of Glucose and Lipid Metabolism

    Not yet reported Central South University 80 participants Est. completion 2020-12-01 Stand-alone
    Other conditions: Psoriasis Vulgaris With Metabolic Disorders
    View official trial listing →
  • Status unknown NCT NCT03639545

    The Effects of Empagliflozin on Arterial Wall Characteristics

    Not yet reported University Medical Centre Ljubljana 120 participants Est. completion 2019-01-30 1 site
    Other conditions: Vascular Stiffness, Hypoglycemic Agents, Diabetes Complications, Diabetes Mellitus, Type 1
    View official trial listing →
  • Withdrawn NCT NCT03640221

    Ertugliflozin Versus Hydrochlorothiazide in Reducing Sympathetic Neural Overactivity in Patients With Hypertension and Recently-diagnosed Type 2 Diabetes.

    Not yet reported Cedars-Sinai Medical Center Est. completion 2020-08-31 1 site
    Type 2 diabetes Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT03651895

    Metformin to Reduce Airway Glucose in COPD Patients

    Not yet reported Imperial College London 14 participants Est. completion 2023-06-01 1 site
    Other conditions: Chronic Obstructive Pulmonary Disease
    View official trial listing →
  • Completed NCT NCT03655301

    Effect of Copanlisib on Metformin Pharmacokinetics and Pharmacodynamics

    Not yet reported Bayer 13 participants Est. completion 2019-02-12 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT03655535

    Multicenter Study to Evaluate the Effect of BTI320 on Glycemic Control in Type 2 Diabetes

    Not yet reported Boston Therapeutics 66 participants Est. completion 2019-08-30 4 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03659461

    Glucagon-like Peptide-1 Levels, Insulin Resistance and Insulin Sensitivity Index in Type 2 Diabetes Mellitus

    Not yet reported National University of Malaysia 174 participants Est. completion 2020-01-31 1 site Stand-alone
    Type 2 diabetesPrediabetes
    View official trial listing →
  • Completed NCT NCT03670043

    Tolerance & Responsiveness Improvement for Metformin (TRIM)

    Not yet reported West Side Institute for Science and Education 29 participants Est. completion 2021-08-15 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03674385

    Efficacy of Vit E in PCOS Resistant to Clomiphene Citrate

    Not yet reported Ain Shams University 60 participants Est. completion 2019-03-30 1 site Stand-alone
    Other conditions: Clomiphene Citrate Resistant Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT03681197

    Metformin Use and Clinical Pregnancy Rate in Women With Unexplained Infertility

    Not yet reported Elham Raafat 170 participants Est. completion 2019-05 1 site
    Other conditions: Infertility
    View official trial listing →
  • Terminated NCT NCT03684642

    Efficacy and Safety of Efpeglenatide Versus Dulaglutide in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin

    Not yet reported Sanofi 908 participants Est. completion 2020-11-17 45 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03684707

    Cancer Chemoprevention by Metformin Hydrochloride Compared to Placebo in Oral Potentially Malignant Lesions

    Not yet reported Ain Shams University 30 participants Est. completion 2019-09-15 1 site
    Other conditions: Oral Cancer
    View official trial listing →
  • Status unknown NCT NCT03685357

    Correlation Between Idiopathic Parkinson's Disease and Diabetes Mellitus

    Ain Shams University 120 participants Est. completion 2020-01 1 site
    Other conditions: Observation
    View official trial listing →
  • Status unknown NCT NCT03685409

    Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions

    Not yet reported Cairo University 62 participants Est. completion 2020-09-30 1 site
    Other conditions: Oral Cancer
    View official trial listing →
  • Withdrawn NCT NCT03686657

    Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes Patients

    Not yet reported, Not yet reported ARKAY Therapeutics Est. completion 2031-01-31 1 site Stand-alone
    Type 2 diabetes Other conditions: High Blood Pressure, Arthritis, Obesity
    View official trial listing →
  • Completed NCT NCT03686722

    Effect of Co-administration of Metformin and Daclatasvir on the Pharmacokinetis and Pharmacodynamics of Metformin

    Not yet reported Mohamed Raslan 20 participants Est. completion 2017-12-06 1 site Stand-alone
    Type 2 diabetes Other conditions: Hepatitis C, Drug Interactions
    View official trial listing →
  • Completed NCT NCT03689374

    A Research Study to Compare Semaglutide to Insulin Aspart, When Taken Together With Metformin and Insulin Glargine, in People With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 2274 participants Est. completion 2021-02-22 210 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03690778

    The PK Characteristics of the Co-administration of Metformin SR and Rosuvastatin and JLP-1310 in Healthy Male Volunteers.

    Not yet reported Jeil Pharmaceutical Co., Ltd. 42 participants Est. completion 2019-02-01 1 site Stand-alone
    Other conditions: Diabetes, Hyperlipidemias
    View official trial listing →
  • Completed NCT NCT03693560

    Effect of Adding Vildagliptin vs Glimepiride to Metformin on Inflammation's Markers in Type-2 Diabetic Patients With CAD

    Not yet reported Damanhour University 80 participants Est. completion 2019-10-10 1 site Stand-alone
    Cardiovascular diseaseType 2 diabetes
    View official trial listing →
  • Completed NCT NCT03700801

    Study of Efficacy, Weight Control, and Safety in Newly-diagnosed Type 2 Diabetes With Different Antidiabetic Therapy

    Not yet reported Zhujiang Hospital 130 participants Est. completion 2019-12-20 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03708549

    Comparison of Berberine and Metformin for the Treatment for MS in Schizophrenia Patients

    Not yet reported Tianjin Anding Hospital 100 participants Est. completion 2023-12-01 1 site Stand-alone
    Metabolic syndrome Other conditions: Schizophrenia, Berberine, Metformin
    View official trial listing →
  • Status unknown NCT NCT03709147

    Metformin Plus/Minus Fasting Mimicking Diet to Target the Metabolic Vulnerabilities of LKB1-inactive Lung Adenocarcinoma

    Not yet reported Marina Garassino 64 participants Est. completion 2023-09-10 1 site Stand-alone
    Other conditions: Advanced LKB1-inactive Lung Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT03710343

    Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study

    Not yet reported Holland Bloorview Kids Rehabilitation Hospital 3 participants Est. completion 2025-04-24 2 sites Stand-alone
    Other conditions: Cerebral Palsy
    View official trial listing →
  • Status unknown NCT NCT03710460

    Effect of Dapagliflozin/Metformin XR vs Monotherapies on Anthropometric Indicators in Obesity

    Not yet reported University of Guadalajara 33 participants Est. completion 2023-12-30 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT03711682

    Reducing Plasma Glucose Effect of Cinnamon in Type 2 Diabetic Patients in the Municipality of Comasagua

    Not yet reported, Not yet reported Universidad Dr. José Matías Delgado 30 participants Est. completion 2018-05-23 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03713801

    Impact of Metformin on Immunity

    Not yet reported The University of Texas Health Science Center at San Antonio 18 participants Est. completion 2024-07-16 1 site Stand-alone
    Other conditions: Aging, Vaccine Response Impaired
    View official trial listing →
  • Completed NCT NCT03714594

    Effects of Dapagliflozin+Saxagliptin in Addition to Metformin v/s Saxagliptin or Dapagliflozin in Patients With DM2.

    Not yet reported University of Pisa 48 participants Est. completion 2022-08-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03717194

    Effect of Ertugliflozin on Cardiac Function in Diabetes

    Not yet reported Soo Lim 102 participants Est. completion 2023-04-30 1 site Stand-alone
    Type 2 diabetesHeart failure
    View official trial listing →
  • Status unknown NCT NCT03717701

    Metformin and Esomeprazole in Treatment of Early Onset Preeclampsia

    Not yet reported Aswan University Hospital 120 participants Est. completion 2021-01-01 1 site Stand-alone
    Other conditions: Pre-Eclampsia
    View official trial listing →
  • Status unknown NCT NCT03718715

    The Interaction Between Metformin and Microbiota - the MEMO Study.

    Umeå University 600 participants Est. completion 2022-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03722290

    Metformin in Children and Adults With Fragile X Syndrome

    Not yet reported Université de Sherbrooke 15 participants Est. completion 2020-11-01 1 site Stand-alone
    Other conditions: Fragile X Syndrome
    View official trial listing →
  • Completed NCT NCT03733132

    Metformin Effect on Brain Function in Insulin Resistant Elderly People

    Not yet reported Mayo Clinic 40 participants Est. completion 2023-04-05 1 site
    Other conditions: Insulin Resistance, Obesity, Obesity, Abdominal
    View official trial listing →
  • Completed NCT NCT03737240

    IDegLira HIGH Trial

    Not yet reported Emory University 145 participants Est. completion 2022-07-08 2 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03746106

    The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine

    Not yet reported University of California, San Francisco 7 participants Est. completion 2023-08-10 1 site Stand-alone
    Other conditions: Vitamin B1 Deficiency, Thiamine Deficiency
    View official trial listing →
  • Completed NCT NCT03748810

    Head-to-head Comparison of Empagliflozin and Dapagliflozin

    Chungbuk National University Hospital 600 participants Est. completion 2022-06-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03751657

    A Research Study to Compare Insulin 287 Once a Week to Insulin Glargine (100 Units/mL) Once a Day in People With Type 2 Diabetes.

    Not yet reported Novo Nordisk A/S 247 participants Est. completion 2020-01-17 49 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03756623

    Effect of Metformin and Probiotics on Gut Microbiome in Healthy Subjects

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 90 participants Est. completion 2019-06-30 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT03757910

    Brain Imaging in the Diabetes Prevention Program Outcomes Study

    Not yet reported José A. Luchsinger 5 participants Est. completion 2023-01-31 1 site Stand-alone
    Other conditions: Alzheimer Disease
    View official trial listing →
  • Status unknown NCT NCT03757923

    Comparison of Metformin and Pioglitazone in Regulating Menstrual Irregularities and Hyperandrogenism

    Not yet reported, Not yet reported Dow University of Health Sciences 110 participants Est. completion 2019-01 1 site Stand-alone
    Other conditions: Menstrual Irregularities, Hyperandrogenism
    View official trial listing →
  • Terminated NCT NCT03761134

    Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Metformin With or Without Sulfonylurea

    Not yet reported Sanofi 377 participants Est. completion 2020-04-29 40 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03764605

    Metformin vs Tolvaptan for Treatment of Autosomal Dominant Polycystic Kidney Disease

    Not yet reported Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari 150 participants Est. completion 2022-01-30 2 sites Stand-alone
    Other conditions: ADPKD
    View official trial listing →
  • Completed NCT NCT03765359

    Metformin Use to Improve Pregnancy Outcome in Women With Type 1 Diabetes.

    Not yet reported Tampere University Hospital 101 participants Est. completion 2022-12-19 5 sites
    Other conditions: Diabetic Pregnancy, Insulin Resistance, Type1diabetes
    View official trial listing →
  • Completed NCT NCT03766256

    Shared Decision Making in Diabetes Prevention for Women With a History of GDM

    Not yet reported University of California, Los Angeles 33 participants Est. completion 2019-12-28 20 sites Stand-alone
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT03766308

    The Clinical Study of the Effect of Highland Barley Diet on Blood Glucose in Patients With Type 2 Diabetes Mellitus

    Not yet reported Xuefeng Yu 40 participants Est. completion 2020-12-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03770052

    Glucose-Lowering Effects and Safety of Adding 0.25 or 0.5 mg Duvie

    Not yet reported Pusan National University Hospital 159 participants Est. completion 2021-09-13 1 site Stand-alone
    Type 2 diabetes Other conditions: Inadequate Glucose Control
    View official trial listing →
  • Terminated NCT NCT03770728

    Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Alone or in Combination With Sulfonylurea

    Not yet reported Sanofi 312 participants Est. completion 2020-12-27 48 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03772262

    Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach

    Not yet reported Washington State University 16 participants Est. completion 2019-03-31 1 site Stand-alone
    Other conditions: Interaction Drug Food
    View official trial listing →
  • Completed NCT NCT03772964

    Effects of Metformin in a Non-Diabetic Patient Population

    Not yet reported, Not yet reported Brian Zuckerbraun 32 participants Est. completion 2020-03-31 1 site Stand-alone
    Other conditions: Inflammatory Response
    View official trial listing →
  • Status unknown NCT NCT03774108

    Metformin and Systemic Inflammation in HIV

    Not yet reported Hospital Civil de Guadalajara 40 participants Est. completion 2020-01-08 1 site Stand-alone
    Prediabetes Other conditions: HIV-1-infection
    View official trial listing →
  • Completed NCT NCT03787017

    A Study to Compare MP-513 20mg & Metformin XR 1000mg FDC With Coadministration of the Two Separate Drugs

    Not yet reported Handok Inc. 36 participants Est. completion 2014-09 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT03787043

    A Study to Evaluate the Effect of Food on Fixed-Dose Combination of MP-513 10 mg and Metformin XR 750 mg

    Not yet reported Handok Inc. 30 participants Est. completion 2014-06 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT03792984

    The Effect of Calcium and Vitamin D Supplements on Metabolic and Hormonal Disturbances in Polycystic Ovary Syndrome Patients

    Not yet reported Damascus University 40 participants Est. completion 2017-12-30 2 sites Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Vitamin D Deficiency/Insufficiency
    View official trial listing →
  • Completed NCT NCT03794336

    Efficacy and Safety of Alogliptin vs. Acarbose in Chinese Type 2 Diabetes Mellitus (T2DM) Patients With High CV Risk or CHD Treated With Aspirin and Inadequately Controlled With Metformin Monotherapy or Drug Naive

    Not yet reported Sanofi 1293 participants Est. completion 2020-12-14 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03796182

    Study of PF 04965842 Effect on MATE1/2K Activity in Healthy Participants

    Not yet reported Pfizer 12 participants Est. completion 2019-03-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03796975

    Efficacy of Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets on the Patients With Newly Diagnosed Type 2 Diabetes Mellitus Combined With Non-alcoholic Fatty Liver Disease

    Not yet reported Xijing Hospital 120 participants Est. completion 2019-11-20 1 site Stand-alone
    Type 2 diabetes Other conditions: Non-alcoholic Fatty Liver Disease, Efficacy
    View official trial listing →
  • Completed NCT NCT03798054

    Evaluation of Insulin Glargine/Lixisenatide Fixed Ratio Combination in Patients With Type 2 Diabetes Insufficiently Controlled With Oral Antidiabetic Drug(s)

    Not yet reported Sanofi 878 participants Est. completion 2021-03-01 79 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03798080

    Comparison of the Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Ratio Combination to Insulin Glargine in Patients With Type 2 Diabetes Insufficiently Controlled on Basal Insulin

    Not yet reported Sanofi 426 participants Est. completion 2020-12-01 45 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03800602

    Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer

    Not yet reported Emory University 29 participants Est. completion 2021-09-04 3 sites Stand-alone
    Obstructive sleep apnea Other conditions: Colorectal Adenocarcinoma, Refractory Colorectal Carcinoma, Stage IV Colorectal Cancer, Stage IVA Colorectal Cancer, Stage IVB Colorectal Cancer, Stage IVC Colorectal Cancer, Colorectal Cancer Metastatic
    View official trial listing →
  • Completed NCT NCT03809260

    A Clinical Trial for Analysis of Intestinal Microbiome Affecting PK, PD, and Safety of Metformin

    Not yet reported Seoul National University Hospital 20 participants Est. completion 2019-02-28 1 site Stand-alone
    Other conditions: Human Microbiome
    View official trial listing →
  • Withdrawn NCT NCT03813316

    Approaches To Therapy Escalation In T2D

    Not yet reported LMC Diabetes & Endocrinology Ltd. Est. completion 2019-09-18 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT03816488

    Oral Peri-operative TIming of Metformin (or) Salsalate to Improve Non-cardiac Surgery Glucose Control

    Not yet reported McMaster University Est. completion 2024-12-01 Stand-alone
    Type 2 diabetes Other conditions: Hyperglycemia, Perioperative/Postoperative Complications, Salsalate to Improve Non-cardiac Surgery Glucose Control
    View official trial listing →
  • Completed NCT NCT03819127

    Vildagliptin in Older Adults With Diabetes and Mild Cognitive Impairment

    Not yet reported University of Catania 60 participants Est. completion 2016-09 Stand-alone
    Other conditions: Mild Cognitive Impairment
    View official trial listing →
  • Completed NCT NCT03819790

    The Effect of Soliqua on Glucose Variability in Type 2 Patients Among South Asians

    Not yet reported LMC Diabetes & Endocrinology Ltd. 119 participants Est. completion 2019-11-19 3 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03824002

    Dulaglutide in Diabetic Patients, Relationship Between Arterial Stiffness, Endothelial Function, Clinical and Laboratory Variables

    Not yet reported University of Palermo 92 participants Est. completion 2018-04-20 1 site Added to GLP-1
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03826602

    A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib on Metformin

    Not yet reported Seagen Inc. 18 participants Est. completion 2019-03-15 1 site Stand-alone
    Other conditions: Drug-drug Interaction
    View official trial listing →
  • Completed NCT NCT03826641

    A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HCP1801 in Healthy Subjects

    Not yet reported Hanmi Pharmaceutical Company Limited 85 participants Est. completion 2019-04-16 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03829020

    Metformin, Nelfinavir, and Bortezomib in Treating Patients With Relapsed and/or Refractory Multiple Myeloma

    Not yet reported Mayo Clinic 9 participants Est. completion 2023-11-24 2 sites Stand-alone
    Other conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
    View official trial listing →
  • Status unknown NCT NCT03831464

    Metformin as RenoProtector of Progressive Kidney Disease

    Not yet reported Universiteit Antwerpen 290 participants Est. completion 2024-12-31 19 sites Stand-alone
    Chronic kidney disease
    View official trial listing →
  • Status unknown NCT NCT03833466

    Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo)

    Not yet reported Peking University 15 participants Est. completion 2020-06-20 1 site Stand-alone
    Other conditions: Esophageal Squamous Cell Carcinoma
    View official trial listing →
  • Completed NCT NCT03841591

    Maternal Weight Gain in Gestational Diabetes Controlled by Metformin Versus Insulin

    Not yet reported Ain Shams University 124 participants Est. completion 2019-01-15 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT03842267

    A Study to Evaluate the Efficacy and Safety of Gemigliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Dapagliflozin and Metformin (SOLUTION Study)

    Not yet reported LG Chem 315 participants Est. completion 2022-11-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03845153

    Metformin Effect on Fracture Healing in Post-Menopausal Women

    Not yet reported Damanhour University 40 participants Est. completion 2021-01-01 1 site
    Other conditions: Bone Fracture
    View official trial listing →
  • Status unknown NCT NCT03848533

    Effect of Melatonin and Metformin on Glycemic Control Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes

    Not yet reported University of Guadalajara 42 participants Est. completion 2021-12 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Completed NCT NCT03850886

    Nicotinamide in Non-Alcoholic Fatty Liver Disease Patients

    Not yet reported Ain Shams University 61 participants Est. completion 2019-08-07 1 site Stand-alone
    Other conditions: Non Alcoholic Fatty Liver Disease
    View official trial listing →
  • Status unknown NCT NCT03851432

    Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin

    Not yet reported Sihuan Pharmaceutical Holdings Group Ltd. 390 participants Est. completion 2021-12-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT03856632

    Liraglutide Effect in Atrial Fibrillation

    Not yet reported University of Miami 60 participants Est. completion 2026-12-31 1 site Added to GLP-1
    Other conditions: Atrial Fibrillation
    View official trial listing →
  • Terminated NCT NCT03861767

    REMAP Trial for Optimizing Surgical Outcomes at UPMC

    Not yet reported Matthew Neal MD 302 participants Est. completion 2022-09-23 1 site Stand-alone
    Other conditions: Aging
    View official trial listing →
  • Completed NCT NCT03862716

    Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IDegLira

    Not yet reported Population Health Research Institute 159 participants Est. completion 2023-07-31 8 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03862950

    A Trial of Metformin in Individuals With Fragile X Syndrome (Met)

    Not yet reported University of Alberta 125 participants Est. completion 2025-12-16 2 sites
    Other conditions: Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X-Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome Disorders
    View official trial listing →
  • Completed NCT NCT03862963

    Lifestyle Intervention to Treat Diabetes in the Marshall Islands

    Not yet reported University of Alabama at Birmingham 138 participants Est. completion 2008-07-31
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03863405

    Metformin Use in Rheumatoid Arthritis

    Not yet reported Ain Shams University 60 participants Est. completion 2020-01-09 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT03864705

    Compliance of Diabetic Patients Treated With Metformin

    Institute for Clinical and Experimental Medicine 400 participants Est. completion 2021-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03871621

    Left Ventricular Functional Changes of Uncontrolled Diabetes by Dapagliflozin Treatment Trial

    Not yet reported Mackay Memorial Hospital 76 participants Est. completion 2022-08-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03874000

    Sintilimab Combined With Metformin in First-Line Chemotherapy Refractory Advanced NSCLC Patients

    Not yet reported Tianjin Medical University Cancer Institute and Hospital 43 participants Est. completion 2022-06-05 1 site Stand-alone
    Other conditions: Non Small Cell Lung Cancer
    View official trial listing →
  • Status unknown NCT NCT03877406

    Effect of Empagliflozin on Body Composition and Ketones

    Not yet reported Seoul National University Bundang Hospital 200 participants Est. completion 2023-12-31 1 site
    Other conditions: Diabetes Mellitus, Fat; Intolerance, Pancreas
    View official trial listing →
  • Status unknown NCT NCT03877783

    DEMAND - Multifactorial Study to Reduce Dementia in People With Type 2 Diabetes

    Not yet reported Umeå University 10 participants Est. completion 2023-06-30 1 site Stand-alone
    Type 2 diabetes Other conditions: Mild Cognitive Impairment
    View official trial listing →
  • Completed NCT NCT03880825

    Drug Interaction Study of Levoketoconazole and Metformin

    Not yet reported Cortendo AB 32 participants Est. completion 2019-05-03 1 site
    Other conditions: Healthy Subjects
    View official trial listing →
  • Active, not recruiting NCT NCT03889795

    Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors

    Not yet reported Danae Hamouda, MD 15 participants Est. completion 2027-12-30 1 site Stand-alone
    Other conditions: Advanced Pancreatic Cancer, Advanced Solid Tumor
    View official trial listing →
  • Completed NCT NCT03893422

    Placebo-Controlled Clinical Nutrition Study of the Safety and Metabolic Effects of Two Medical Foods in Type 2 Diabetes

    Not yet reported Pendulum Therapeutics 76 participants Est. completion 2018-09-14 5 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03898037

    Effect of Lifestyle and/or Metformin Intervention on Pregnancy Outcome, A Pilot Randomized Controlled Trial

    Not yet reported Reproductive & Genetic Hospital of CITIC-Xiangya 80 participants Est. completion 2021-06-30 1 site Stand-alone
    Other conditions: Infertility, Female, Obesity, Insulin Resistance
    View official trial listing →
  • Withdrawn NCT NCT03905941

    Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age

    Not yet reported University of Virginia Est. completion 2024-11-25 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Terminated NCT NCT03907202

    A Clinical Study to Evaluate the Safety, Tolerability, PK, PD, and Efficacy of KBP-089 in Patients With T2DM

    Not yet reported KeyBioscience AG 25 participants Est. completion 2019-12-03 1 site
    Other conditions: Type II Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03907423

    Rosuvastatin on Diabetic Patients Treated With Glimepiride/Metformin

    Not yet reported Rehab Werida 70 participants Est. completion 2021-01-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03916263

    Low Starch Dietary Education Program vs. Traditional Treatment for PCOS

    Not yet reported Texas Tech University Health Sciences Center 71 participants Est. completion 2022-12-31 1 site Stand-alone
    Other conditions: PCOS, Diet Modification, Metabolism, Nutrition Disorders
    View official trial listing →
  • Status unknown NCT NCT03917758

    Antidiuretic Function Before and During Treatment With SGLT2 Inhibitors

    Not yet reported University of Turin, Italy 30 participants Est. completion 2020-10-30 1 site Stand-alone
    Type 2 diabetes Other conditions: Arterial Hypertension, Body Weight Changes
    View official trial listing →
  • Completed NCT NCT03918148

    Gliflozins and Cardiovascular Risk Factors in Type 2 Diabetes (GIOIA)

    University of Campania Luigi Vanvitelli 1150 participants Est. completion 2023-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03921242

    Comparative Effectiveness of Metformin for Type 2 Diabetes With Chronic Kidney Disease

    Weill Medical College of Cornell University 4888 participants Est. completion 2023-08-01 2 sites
    Type 2 diabetes Other conditions: Renal Insufficiency, Chronic
    View official trial listing →
  • Completed NCT NCT03922750

    A Research Study in People With Type 2 Diabetes to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine

    Not yet reported Novo Nordisk A/S 154 participants Est. completion 2020-01-27 38 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03927170

    Pharmacokinetic Characteristics of GLH1SM Extended Release Tablets in Healthy Volunteers(Fed)

    Not yet reported GL Pharm Tech Corporation 25 participants Est. completion 2019-10-23 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03928340

    Effect of Adding Metformin to Insulin Therapy on Pregnancy Outcomes in Women With Uncontrolled Type I Diabetes.

    Not yet reported Kasr El Aini Hospital 80 participants Est. completion 2020-03-29 1 site
    Other conditions: Type1 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT03934021

    Gut Microbiota in Acute Stroke Patients

    Chinese University of Hong Kong 120 participants Est. completion 2024-08-30 1 site
    Cardiovascular disease Other conditions: Microbiome, Atherosclerosis Cerebral
    View official trial listing →
  • Completed NCT NCT03945656

    A Research Study of How Overdosing of a New Once Weekly Medicine NNC0148-0287 C (Insulin 287) Influences the Blood Sugar Level in People With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 43 participants Est. completion 2021-09-27 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03950505

    To Evaluate the Effect of Nesinaact on Non-alcoholic Steatohepatitis Through MRI and Liver Fibroscan in Patients With Type 2 Diabetes

    Not yet reported Yonsei University 60 participants Est. completion 2020-12 1 site
    Type 2 diabetes Other conditions: Non-alcoholic Steatohepatitis
    View official trial listing →
  • Completed NCT NCT03951805

    A Research Study to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine in People With Type 2 Diabetes Who Have Not Used Insulin Before

    Not yet reported Novo Nordisk A/S 205 participants Est. completion 2020-01-17 43 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03956290

    Time Restricted EATing (TREAT) Pilot Study

    Not yet reported Columbia University 64 participants Est. completion 2021-01-11 1 site
    Other conditions: Overweight and Obesity, Pre Diabetes
    View official trial listing →
  • Completed NCT NCT03958591

    Impact of Short-term Intensive De-escalation Therapy on Long-term Regimen Simplification

    Not yet reported Yanbing Li 276 participants Est. completion 2026-03-31 1 site Stand-alone
    Other conditions: Diabetes type2
    View official trial listing →
  • Completed NCT NCT03960333

    Immunometabolism in Pediatric Obesity

    Arkansas Children's Hospital Research Institute 82 participants Est. completion 2024-06-30 1 site
    Type 2 diabetes Other conditions: Obesity, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT03961659

    Effects of Liraglutid, Dapagliflozin and Acarbose on the Cognitive Function, Olfactory Function, and Odor-induced Brain Activation in Overweight/Obese T2DM Patients Controlled Inadequately With Metformin Monotherapy.

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 87 participants Est. completion 2021-02 1 site
    Type 2 diabetes Other conditions: Obesity, Cognitive Impairment
    View official trial listing →
  • Completed NCT NCT03967496

    Assessment of Immediate Postoperative Delirium (IPD) in Adult Patients: Incidence and Etiologic Factors

    Sultan Qaboos University 402 participants Est. completion 2019-03-31 1 site
    Other conditions: Delirium, Anesthesia; Adverse Effect
    View official trial listing →
  • Completed NCT NCT03968224

    Effectiveness of Dapagliflozin for Weight Loss

    Not yet reported, Not yet reported Centro Medico Nacional Siglo XXI IMSS 160 participants Est. completion 2024-07-31 1 site Stand-alone
    PrediabetesType 2 diabetes Other conditions: Obesity, Morbid
    View official trial listing →
  • Completed NCT NCT03969719

    A Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus

    Not yet reported Pfizer 164 participants Est. completion 2021-03-30 106 sites
    Other conditions: Non-alcoholic Steatohepatitis
    View official trial listing →
  • Completed NCT NCT03970434

    Drug Concentration of Metformin According to Sampling Method

    Not yet reported Chonbuk National University Hospital 20 participants Est. completion 2019-06-05 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT03972982

    Effects of Structured Simplified Short-term Intensive Insulin Therapy on Long-term Glycemic Remission

    Not yet reported Sun Yat-sen University 330 participants Est. completion 2022-12-31 1 site Stand-alone
    Type 2 diabetes Other conditions: Simplified Short-term Intensive Insulin Therapy, Glycemic Remission
    View official trial listing →
  • Status unknown NCT NCT03974139

    Impact of Metformin on Leptin Transport in Cerebrospinal Fluid of Obese Patients

    Not yet reported Lille Catholic University 31 participants Est. completion 2024-09-30 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03980990

    Metformin Continuation Versus Interruption Following Coronary Angiography: a Pilot Randomized Controlled Trial

    Not yet reported University of Saskatchewan 500 participants Est. completion 2020-06-17 1 site Stand-alone
    Other conditions: Acute Coronary Syndrome, Unstable Angina, Diabetes Mellitus, Metformin Adverse Reaction
    View official trial listing →
  • Completed NCT NCT03981861

    Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents

    Not yet reported, Not yet reported Children's Mercy Hospital Kansas City 12 participants Est. completion 2019-06-05 1 site Stand-alone
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT03982238

    Effects of Hypoglycemic Drugs on Testosterone Levels in Type 2 Diabetes Patients

    Not yet reported Majianhua 74 participants Est. completion 2019-12-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03982381

    SGLT2 Inhibitor or Metformin as Standard Treatment of Early Stage Type 2 Diabetes

    Not yet reported Uppsala University 2067 participants Est. completion 2026-01-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT03983551

    Comparing the Renal Effect of Dipeptidyl-peptidase 4 Inhibitors and Sulfonylureas

    Not yet reported Changhua Christian Hospital 101 participants Est. completion 2018-02-28 Stand-alone
    Type 2 diabetes Other conditions: Proteinuria
    View official trial listing →
  • Completed NCT NCT03987919

    A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 1879 participants Est. completion 2021-02-15 127 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT03994744

    Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLC

    Not yet reported Hunan Cancer Hospital 68 participants Est. completion 2022-07-01 1 site Stand-alone
    Other conditions: Small-cell Lung Cancer, Small Cell Lung Carcinoma, Small Cell Lung Cancer Recurrent, Small Cell Lung Cancer Extensive Stage
    View official trial listing →
  • Completed NCT NCT03996538

    Vaccination Efficacy With Metformin in Older Adults

    Not yet reported UConn Health 26 participants Est. completion 2020-02-04 1 site Stand-alone
    Other conditions: Aging, Age-Related Immunodeficiency, Vaccine Response Impaired
    View official trial listing →
  • Status unknown NCT NCT04001725

    Efficacy of metfOrmin in PrevenTIng Glucocorticoid-induced Diabetes in Patients With Brain Metastases

    Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 110 participants Est. completion 2022-03-31 1 site Stand-alone
    Other conditions: Brain Metastases, Melanoma, Lung Cancer, Breast Cancer
    View official trial listing →
  • Completed NCT NCT04008186

    A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone

    Not yet reported Biogen 61 participants Est. completion 2019-08-28 1 site Stand-alone
    Other conditions: Healthy Adult Subjects
    View official trial listing →
  • Completed NCT NCT04009603

    Comparison of Probiotics, Metformin & Their Combination Therapy in the Treatment of PCOS

    Not yet reported Ziauddin University 78 participants Est. completion 2020-01-28 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04010942

    Vitamin D for Polycystic Ovary Syndrome Clomiphene Resistant Women

    Not yet reported Ain Shams University 120 participants Est. completion 2019-03-30 1 site
    Other conditions: PCOS, Vitamin D Deficiency
    View official trial listing →
  • Completed NCT NCT04013581

    Quadruple Oral Combination Therapy for Type 2 Diabetes Mellitus : Glycemic Control by Thiazolidinedione (TZD) or Sodium Glucose Co-transporter 2 (SGLT-2) Inhibitor as an add-on Therapy in Type 2 Diabetes Mellitus After Failure of an Oral Triple Antidiabetic Regimen

    Not yet reported Yonsei University 121 participants Est. completion 2020-05-28 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04017221

    Safety of Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors Among Patients With Type 2 Diabetes

    Canadian Network for Observational Drug Effect Studies, CNODES 1249636 participants Est. completion 2019-12-01 1 site
    Type 2 diabetes Other conditions: Urosepsis, Diabetic Ketoacidosis, Lower Extremity Amputation
    View official trial listing →
  • Completed NCT NCT04017832

    A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 1441 participants Est. completion 2021-10-27 93 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04018105

    Influence of Preprandial Metformin Administration on Carbohydrate Absorption

    Not yet reported University Hospital, Lille 1 participants Est. completion 2025-04-05 Stand-alone
    PrediabetesType 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04027023

    Evaluation of the Impact of Intensive Short-Term Drug Therapy in Patients With Type 2 Diabetes Mellitus

    Not yet reported Sciema UG 9 participants Est. completion 2021-05-31 2 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04029272

    Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients

    Not yet reported Peking Union Medical College Hospital 80 participants Est. completion 2020-12-31 1 site Added to GLP-1
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04029480

    Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

    Not yet reported Merck Sharp & Dohme LLC 166 participants Est. completion 2025-04-11 104 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04033107

    High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors

    Not yet reported Zhongnan Hospital 30 participants Est. completion 2024-12 1 site Stand-alone
    Other conditions: Hepatocellular Cancer, Pancreatic Cancer, Gastric Cancer, Colorectal Cancer
    View official trial listing →
  • Completed NCT NCT04039503

    A Study of Tirzepatide (LY3298176) Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine With or Without Metformin

    Not yet reported Eli Lilly and Company 475 participants Est. completion 2021-01-13 48 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04043221

    Long Term Metformin in Women With Polycystic Ovary Syndrome

    University Medical Centre Ljubljana 180 participants Est. completion 2019-01-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Terminated NCT NCT04047537

    Placebo-Controlled Clinical Nutrition Study of the Metabolic Effects of Food Product WBF-0011 in Type 2 Diabetes

    Not yet reported Pendulum Therapeutics 41 participants Est. completion 2020-05-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04047940

    A Study of LY900020 in Healthy Chinese Participants

    Not yet reported Eli Lilly and Company 32 participants Est. completion 2020-02-18 1 site
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT04050098

    Bioequivalence Study for Gemigliptin/Metformin 50/1000 mg and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.

    Not yet reported LG Chem 24 participants Est. completion 2019-11-30
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04053621

    Co-administration of Thiamine Pyrophosphate and Metformin in Type 2 Diabetes

    Not yet reported Laboratorios Manuell SA 92 participants Est. completion 2022-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04064073

    Study to Evaluate Drug-Drug Interaction of DWP16001 in Combination With Metformin in Healthy Male Adults (Phase 1 Study)

    Not yet reported Daewoong Pharmaceutical Co. LTD. 34 participants Est. completion 2019-11-20 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT04065581

    Bioequivalence Study for Acarbose/Metformin FDC

    Not yet reported Bayer 24 participants Est. completion 2020-03-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04068246

    The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Rheumatoid Arthritis Patients

    Not yet reported, Not yet reported Sadat City University 120 participants Est. completion 2021-02-28 1 site Stand-alone
    Other conditions: Rheumatoid Arthritis
    View official trial listing →
  • Status unknown NCT NCT04070794

    Food-effect Bioavailability of Fixed Dose Combination Zemimet® SR Tab. 50/1000 mg Under Fed and Fasting Conditions

    Not yet reported LG Chem 24 participants Est. completion 2019-12-30
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04075110

    Investigation the Safety and Efficacy of The Antileukotriene Agents, Montelukast, as Adjuvant Therapy in Obese Patients With Type 2 Diabetes Mellitus

    Not yet reported Sadat City University 100 participants Est. completion 2023-04-10 1 site Stand-alone
    Other conditions: Obesity; Endocrine; Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT04081857

    A Study to Evaluate the Pharmacokinetics and Safety of HCP1704 in Healthy Subjects

    Not yet reported Hanmi Pharmaceutical Company Limited 48 participants Est. completion 2019-08-05 1 site Stand-alone
    Other conditions: Health, Subjective
    View official trial listing →
  • Completed NCT NCT04088448

    The Antidiabetic Metformin as a Novel Adjunct to Antidepressants in Major Depressive Disorder Patients

    Not yet reported, Not yet reported Sadat City University 80 participants Est. completion 2020-06-01 1 site Stand-alone
    Other conditions: Major Depressive Disorder
    View official trial listing →
  • Completed NCT NCT04088461

    Effect of Linagliptin + Metformin on Patients Who do Not Achieve Normoglucemia With Metformine

    Not yet reported Universidad de Guanajuato 31 participants Est. completion 2018-09 1 site Stand-alone
    Prediabetes Other conditions: Prediabetic State, Insulin Resistance
    View official trial listing →
  • Active, not recruiting NCT NCT04088851

    "Hepatic Substrate Flux Rates in Type 2 Diabetes"

    Not yet reported German Diabetes Center 23 participants Est. completion 2025-12-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04089813

    Effect of Metformin on Chronic Pain After Thoracic Surgery in Diabetic Patients

    Xuzhou Medical University 200 participants Est. completion 2020-12-31 1 site
    Other conditions: Postoperative Chronic Pain
    View official trial listing →
  • Completed NCT NCT04090580

    Impact on Glycemic Variability in Newly Onset T2DM Patients Initiating Dapagliflozin Plus Metformin Versus Metformin Alone

    Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 88 participants Est. completion 2021-03-30 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04093752

    A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes on Metformin With or Without Sulfonylurea (SURPASS-AP-Combo)

    Not yet reported Eli Lilly and Company 917 participants Est. completion 2021-11-24 67 sites
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04098666

    Metformin in Alzheimer's Dementia Prevention

    Not yet reported, Not yet reported Columbia University 326 participants Est. completion 2027-04-30 22 sites Stand-alone
    Other conditions: Mild Cognitive Impairment
    View official trial listing →
  • Completed NCT NCT04113889

    Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress in Patients With Poly Cystic Ovary Syndrome

    Not yet reported Khyber Medical University Peshawar 147 participants Est. completion 2020-01-30 1 site
    Other conditions: PCOS
    View official trial listing →
  • Active, not recruiting NCT NCT04114682

    Longitudinal Assessment of Multiple Organs in Patients With Type 2 Diabetes

    Perspectum 135 participants Est. completion 2026-09-30 4 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04120259

    Effect of Apple Cider Vinegar and Metformin Combination vs Metformin Alone in Type 2 Diabetics

    Not yet reported Ziauddin University 126 participants Est. completion 2019-08-26 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04131582

    Effect of Empagliflozin + Linagliptin + Metformin + Lifestyle in Patients With Prediabetes

    Not yet reported Universidad de Guanajuato 34 participants Est. completion 2020-12-30 1 site Stand-alone
    Other conditions: Prediabetic State, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT04134650

    Effect of Low Dose Combination of Linagliptin + Metformin to Prevent Diabetes

    Not yet reported Universidad de Guanajuato 34 participants Est. completion 2020-07-01 1 site Stand-alone
    Other conditions: Prediabetic State, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT04141163

    Metformin in Patients With Fragile X

    Not yet reported, Not yet reported Rowan University 40 participants Est. completion 2021-03 1 site Stand-alone
    Other conditions: Fragile X Syndrome
    View official trial listing →
  • Completed NCT NCT04143282

    Evaluation of the Effect of Metformin on Metastatic Breast Cancer as Adjuvant Treatment

    Not yet reported Hager salah el din 250 participants Est. completion 2020-06-30 1 site Stand-alone
    Other conditions: Metastatic Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT04145687

    Metformin In Prevention of Lupus Nephritis

    Not yet reported RenJi Hospital 30 participants Est. completion 2022-06 1 site
    Other conditions: Lupus Nephritis
    View official trial listing →
  • Status unknown NCT NCT04146155

    Efficacy and Safety of Liraglutide in Type 2 Diabetes With Lower Extremity Arterial Disease

    Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 200 participants Est. completion 2021-12-31 1 site
    Type 2 diabetes Other conditions: Peripheral Vascular Disorder Due to Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT04148183

    Effect of Metformin and Rosiglitazone Over no Diabetic With Metabolic Syndrome Patients.

    Not yet reported, Not yet reported J JESUS VENEGAS, MD 30 participants Est. completion 2009-01-01 Stand-alone
    Other conditions: Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT04151459

    Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients

    Not yet reported RenJi Hospital 18 participants Est. completion 2022-01-15 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Severe Obesity, Laparoscopic Sleeve Gastrectomy
    View official trial listing →
  • Status unknown NCT NCT04155164

    Effect of Metformin on Visual Function in Patients With Glaucoma

    Not yet reported Zhongshan Ophthalmic Center, Sun Yat-sen University 40 participants Est. completion 2024-05 1 site Stand-alone
    Other conditions: Primary Open Angle Glaucoma
    View official trial listing →
  • Completed NCT NCT04156750

    A Study of LY3556050 in Healthy Participants

    Not yet reported Eli Lilly and Company 34 participants Est. completion 2020-08-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT04161404

    Pharmacometabolomics of Andrographis Paniculata And Metformin In Healthy Volunteers Under Fasting Condition

    Not yet reported University of Malaya 18 participants Est. completion 2020-12-31 1 site Stand-alone
    Other conditions: Pharmacokinetics, Molecular Mechanisms of Pharmacological Action
    View official trial listing →
  • Completed NCT NCT04170439

    Added Value of N Acetyle Cysteine to Clomiphene Citrate in PCO

    Not yet reported Aljazeera Hospital 108 participants Est. completion 2020-05-15 2 sites
    Other conditions: PCO
    View official trial listing →
  • Completed NCT NCT04170465

    Role of Adding Metformin to Neoadjuvant Chemotherapy in Patients With Breast Cancer (METNEO)

    Not yet reported Damanhour University 70 participants Est. completion 2022-06-28 1 site Stand-alone
    Other conditions: Breast Cancer Female
    View official trial listing →
  • Terminated NCT NCT04170959

    The Addition of Metformin to Definitive Radiotherapy in Patients With Stage III NSCLC

    Not yet reported ethisch.comite@uza.be 3 participants Est. completion 2021-01-08 1 site
    Other conditions: Carcinoma, Non-Small-Cell Lung
    View official trial listing →
  • Completed NCT NCT04170998

    Efficacy and Safety of Evogliptin When Added to Ongoing Metformin and Dapagliflozin Combination Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control

    Not yet reported Dong-A ST Co., Ltd. 283 participants Est. completion 2021-12-08 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04175964

    Role of the Ketogenic Diet in Women With PCOS

    Not yet reported National Research Centre, Egypt 240 participants Est. completion 2023-06-30 Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT04177303

    Incretin Hormones in Type 1 Diabetes Mellitus;Effect of Metformin Treatment

    Not yet reported Hellenic Institute for the Study of Sepsis 44 participants Est. completion 2022-11-29 1 site
    Other conditions: Type 1 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT04181307

    A Randomized Trial of a BE-EHR Module to Guide the Care of Older Adults With Diabetes

    Not yet reported NYU Langone Health 7630 participants Est. completion 2022-07-01 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT04182321

    Metformin as Add-on to the Standard Therapy in Patients With Chronic Hepatitis B

    Not yet reported Fu-Sheng Wang 60 participants Est. completion 2021-09-13 1 site Stand-alone
    Other conditions: Chronic Hepatitis B
    View official trial listing →
  • Completed NCT NCT04183868

    Effects of empagliFlozin on myocardIal metabOlic Rate of glucosE Estimated Through 18FDG PET (FIORE Study)

    Not yet reported University of Catanzaro 26 participants Est. completion 2021-10 1 site Stand-alone
    Type 2 diabetes Other conditions: Cardiovascular Risk Factor
    View official trial listing →
  • Completed NCT NCT04192292

    Study of Sulphonylurea Synergy With DPP4 Inhibitors

    Not yet reported University of Dundee 30 participants Est. completion 2020-12-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04194424

    A Multidisciplinary Weight Loss Program at AUB-MC

    Not yet reported American University of Beirut Medical Center 20 participants Est. completion 2026-09-15 1 site Stand-alone
    Other conditions: Obesity, Weight Loss
    View official trial listing →
  • Status unknown NCT NCT04194515

    Gut Microbiota and Bile Acids in Type 2 Diabetes Mellitus

    Chang Gung Memorial Hospital 50 participants Est. completion 2021-12-31 1 site
    Type 2 diabetes Other conditions: Metformin, YH1
    View official trial listing →
  • Status unknown NCT NCT04195243

    Dapagliflozin vs Empagliflozin on Flow Mediated Dilation in Type 2 Diabetes Mellitus

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2020-12-30 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04200625

    Semaglutide vs Dulaglutide on Epicardial Adipose Tissue

    University of Miami 80 participants Est. completion 2019-12-09 1 site
    Other conditions: Epicardial Fat
    View official trial listing →
  • Status unknown NCT NCT04204044

    Comparison of Myoinositol and Metformin in PCO

    Not yet reported Rashid Latif Medical College 126 participants Est. completion 2021-07-25 1 site Stand-alone
    Other conditions: PCOS
    View official trial listing →
  • Active, not recruiting NCT NCT04207944

    The Prevention of Progression to Pancreatic Cancer Trial (The 3P-C Trial)

    Not yet reported Duke University 100 participants Est. completion 2026-10-31 4 sites Stand-alone
    Other conditions: IPMN, IPMN, Pancreatic
    View official trial listing →
  • Completed NCT NCT04209075

    Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)

    Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 6 participants Est. completion 2021-07-15 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT04218734

    A Study of DBPR108 and Metformin Hydrochloride Combination Therapy in Patients With T2DM

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 214 participants Est. completion 2021-06-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04220021

    Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD

    Not yet reported University of Florida 41 participants Est. completion 2027-08-31 1 site Stand-alone
    Other conditions: C9orf72 Amyotrophic Lateral Sclerosis (ALS), Frontotemporal Dementia
    View official trial listing →
  • Completed NCT NCT04221750

    Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors

    Not yet reported VA Office of Research and Development 114 participants Est. completion 2025-07-31 1 site Stand-alone
    Other conditions: Frailty, Sarcopenic Obesity, Aging
    View official trial listing →
  • Status unknown NCT NCT04222348

    MeDiGes Study: Metformine Use in Gestational Diabetes

    Not yet reported Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud 200 participants Est. completion 2020-07-01 Stand-alone
    Other conditions: Diabetes, Gestational, Perinatal Disorder, Puerperal Disorder
    View official trial listing →
  • Status unknown NCT NCT04224051

    Metformin for Abdominal Aortic Aneurysm Growth Inhibition

    Not yet reported Uppsala University Hospital 500 participants Est. completion 2026-01 1 site Stand-alone
    Other conditions: Abdominal Aortic Aneurysm
    View official trial listing →
  • Completed NCT NCT04231435

    Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and Metformin

    Not yet reported Celgene 24 participants Est. completion 2020-02-21 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT04233437

    Drug-Drug Interaction Study of MLC1501 Using Cocktail of Drugs Acting as Sensitive Clinical Probes/Substrates of Cytochrome P450 Isoenzymes and Transporters in Healthy Subjects

    Not yet reported Moleac Pte Ltd. 27 participants Est. completion 2020-05-16 1 site Stand-alone
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT04237493

    Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan

    Not yet reported University of Jordan 687 participants Est. completion 2017-07-24 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04245644

    Efficacy of Chemopreventive Agents on Disease-free and Overall Survival in Patients With Pancreatic Ductal Adenocarcinoma: The CAOS Study

    Massimo Falconi 800 participants Est. completion 2024-12-31 1 site
    Other conditions: Disease Free Survival, Overall Survival, Pancreatic Cancer
    View official trial listing →
  • Status unknown NCT NCT04248998

    Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer

    Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 30 participants Est. completion 2024-05-01 1 site Stand-alone
    Other conditions: Triple-negative Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT04255238

    A Study to Evaluate the Efficacy and Safety of Dual add-on Therapy With Gemigliptin 50 mg and Dapagliflozin 10 mg Added to Metformin Who Have Inadequate Glycemic Control on Metformin Alone

    Not yet reported LG Chem 468 participants Est. completion 2022-12-30
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04264897

    Antecedent Metabolic Health and Metformin Aging Study

    Not yet reported Oklahoma Medical Research Foundation 166 participants Est. completion 2025-03-12 2 sites Stand-alone
    Other conditions: Aging, Insulin Sensitivity, Chronic Disease, Mitochondria, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT04267809

    Modulate Cellular Stress in the Immune Cells to Reduce Rate of Symptomatic Viral Infection

    Not yet reported Singapore General Hospital 32 participants Est. completion 2023-07-31 1 site Stand-alone
    Other conditions: Endoplasmic Reticulum Stress, Viral Infection, Yellow Fever
    View official trial listing →
  • Completed NCT NCT04268394

    A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

    Not yet reported Celgene 48 participants Est. completion 2021-06-02 1 site Stand-alone
    Other conditions: Healthy Volunteer
    View official trial listing →
  • Status unknown NCT NCT04268563

    Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients

    Not yet reported, Not yet reported Shahid Beheshti University of Medical Sciences 80 participants Est. completion 2021-07-30 1 site
    Other conditions: Polycystic Ovary Syndrome, Infertility, ART
    View official trial listing →
  • Completed NCT NCT04271189

    Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs

    Not yet reported Azienda Ospedaliero-Universitaria di Parma 108 participants Est. completion 2024-12-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04272359

    Substitution of Sulfonylureas With New Generation of Hypoglycemic Drugs for the Treatment of Type 2 Diabetes Mellitus

    University of Milan 138 participants Est. completion 2021-12-31 1 site
    Type 2 diabetes Other conditions: Diet, Healthy, Renal Function Disorder, Albuminuria
    View official trial listing →
  • Completed NCT NCT04275713

    Altered Tumor Oxygenation by Metformin, a Potential Step in Overcoming Radiotherapy Resistance in LACC

    Not yet reported Oslo University Hospital 41 participants Est. completion 2024-11-08 1 site Stand-alone
    Other conditions: Cervical Cancer
    View official trial listing →
  • Completed NCT NCT04283318

    Prolonged Fasting on Glucose Metabolism and Hormonal Regulation in Healthy, Obese and Subjects With Type 2 Diabetes

    Not yet reported Medical University of Graz 80 participants Est. completion 2022-02-28 1 site
    Type 2 diabetes Other conditions: Healthy, Obesity, Type 1 Diabetes
    View official trial listing →
  • Status unknown NCT NCT04284722

    Perioperative Continuation of Metformin Therapy in Patients With Typ 2 Diabetes Mellitus Undergoing Non-cardiac Surgery

    Not yet reported Kepler University Hospital 400 participants Est. completion 2021-04
    Type 2 diabetes Other conditions: Hyperglycemia, Metformin, Hyperlactatemia
    View official trial listing →
  • Status unknown NCT NCT04287387

    Response of Gut Microbiota in Type 2 Diabetes to Hypoglycemic Agents

    Not yet reported Peking Union Medical College Hospital 180 participants Est. completion 2021-03-02 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04288778

    A Study to Assess Safety of Canagliflozin and Metformin Hydrochloride Combination Given as a Supplement to Diet and Exercise to Improve Blood Sugar Level in Indian Adult Participants With Diabetes

    Not yet reported Johnson & Johnson Private Limited 276 participants Est. completion 2022-07-26 10 sites Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT04295031

    Metformin in Older Adults With Type 2 Diabetes (AMEMET)

    Associazione Medici Endocrinologi 1500 participants Est. completion 2021-03-15 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04298684

    Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules in Type 2 Diabetes

    Not yet reported Centre Hospitalier Universitaire de la Guadeloupe 90 participants Est. completion 2024-07-01 4 sites Stand-alone
    Type 2 diabetes Other conditions: Thyroid Nodule (Benign)
    View official trial listing →
  • Completed NCT NCT04300790

    Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients

    Not yet reported MedSIR 69 participants Est. completion 2025-03-16 19 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT04317703

    Bioequivalence Study for Fixed Dose Combination Zemimet® SR Tab. 50/1000 and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.

    Not yet reported LG Chem 40 participants Est. completion 2020-09-05 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04326166

    Observational Study to Evaluate the Efficacy and Safety of Suganon Tab. or Sugamet XR Tab.

    Dong-A ST Co., Ltd. 1971 participants Est. completion 2021-07-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04332393

    Metformin to Treat Corticosteroids-induced Hyperglycemia

    Not yet reported The Baruch Padeh Medical Center, Poriya 187 participants Est. completion 2025-05-05 4 sites Stand-alone
    Other conditions: Pregnancy Preterm, Glycemic Control, Corticosteroids Induced Hyperglycemia
    View official trial listing →
  • Completed NCT NCT04335526

    A Clinical Study to Assess the Effect of Change of Bile Acid on the PD and Safety of Metformin and Microbiome Profiles

    Not yet reported Seoul National University Hospital 15 participants Est. completion 2020-10-21 1 site
    Other conditions: Human Microbiome
    View official trial listing →
  • Active, not recruiting NCT NCT04341571

    Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes.

    Not yet reported University of Guadalajara 30 participants Est. completion 2026-12 1 site Stand-alone
    Prediabetes Other conditions: Hyperglycemia, Resistance, Insulin
    View official trial listing →
  • Completed NCT NCT04343872

    Preventing Diabetes in the Deep South: Extending Partnerships and Adapting Interventions to Reach Rural Communities at High Risk.

    Not yet reported University of Alabama at Birmingham 36 participants Est. completion 2022-12-31 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Completed NCT NCT04356742

    Efficacy and Safety of Dapagliflozin When Added to Ongoing Metformin and Evogliptin Combination Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control

    Not yet reported Dong-A ST Co., Ltd. 198 participants Est. completion 2022-02-23 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04373967

    Study to Assess the Efficacy and Safety of Liraglutide in the Treatment of Type 2 Diabetes

    Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 424 participants Est. completion 2021-12-02 46 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04377321

    Colchicine Has Anti-diabetic Effect

    Ministry of Health and Population, Egypt 150 participants Est. completion 2020-05-02 1 site
    Other conditions: Treatment Adherence
    View official trial listing →
  • Completed NCT NCT04377451

    Metformin in Dengue With Obesity

    Not yet reported, Not yet reported Oxford University Clinical Research Unit, Vietnam 120 participants Est. completion 2023-08-01 1 site Stand-alone
    Other conditions: Dengue, Viral Infection, Metformin, Anti-inflammatory Agents, Obesity, Overweight
    View official trial listing →
  • Status unknown NCT NCT04387630

    Neoadjuvant Chemotherapy With or Without Metformin in Early Breast Cancer.

    Not yet reported, Not yet reported Mansoura University 120 participants Est. completion 2023-05-01 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT04390295

    Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 450 participants Est. completion 2020-05 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04392284

    Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics

    Not yet reported University of Alabama at Birmingham 40 participants Est. completion 2022-06-03 1 site Stand-alone
    Metabolic syndrome Other conditions: Insulin Resistance, Obesity, Diabetes, Hypertension, Dyslipidemias
    View official trial listing →
  • Status unknown NCT NCT04392557

    Anti-inflammatory Status in DM2 Treated Patients

    Not yet reported University of Catanzaro 36 participants Est. completion 2021-06-20 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04407650

    Ursodeoxycholic Acid vs Metformin in Gestational Diabetes Mellitus

    Not yet reported King's College London 64 participants Est. completion 2025-05-31 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT04409795

    Oral Hypoglycemic Therapy for Monogenic Variant Carriers of the Joslin Medalist Study

    Not yet reported, Not yet reported Joslin Diabetes Center 3 participants Est. completion 2024-12-31 1 site
    Other conditions: Type 1 Diabetes, Monogenic Diabetes
    View official trial listing →
  • Status unknown NCT NCT04412746

    Covid-19 and Diabetes in West of Algeria

    Laboratoire De Recherche Sur Le Diabete, Université de Tlemcen 100 participants Est. completion 2020-06-30 1 site
    Other conditions: Coronavirus Infections, Diabetes Mellitus, Prevalence, Risk Factors, Patient Outcome Assessment, Severe Acute Respiratory Syndrome
    View official trial listing →
  • Terminated NCT NCT04416269

    Oral Anti Diabetic Agents in the Hospital

    Not yet reported Emory University 85 participants Est. completion 2025-04-11 3 sites Added to GLP-1
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT04419337

    Pioglitazone and SGLT2 Inhibitors vs. DPP4 Inhibitors in Patients With Stroke

    Not yet reported Chang Gung Memorial Hospital 200 participants Est. completion 2024-01-31 1 site Stand-alone
    Cardiovascular disease Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT04428086

    A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects.

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 19 participants Est. completion 2021-08-22 1 site Stand-alone
    Other conditions: Solid Tumor, Adult
    View official trial listing →
  • Completed NCT NCT04448821

    A Clinical Trial to Evaluate the Effect of Nilotinib on the PK/PD of Meformin

    Not yet reported Hyewon Chung 16 participants Est. completion 2020-09-07 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Active, not recruiting NCT NCT04451837

    Semaglutide and Dapagliflozin in Diabetic Patients With Different Pathophysiology

    Not yet reported Region Skane 200 participants Est. completion 2026-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04465877

    Study to Evaluate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of JTT-662 in Subjects With Type 2 Diabetes

    Not yet reported Akros Pharma Inc. 37 participants Est. completion 2021-02-17 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT04468243

    Pilot RCT Feasibility Study: Cancer and T2D

    Not yet reported University of Florida 3 participants Est. completion 2021-12-13 1 site Stand-alone
    Type 2 diabetes Other conditions: Cancer
    View official trial listing →
  • Status unknown NCT NCT04477590

    Interactions of Medicine and Exercise With Meal Timing

    Not yet reported University of Castilla-La Mancha 160 participants Est. completion 2024-12-30 1 site
    Metabolic syndrome Other conditions: Exercise Training, Metformin, Statins, Angiotensin-Converting-Enzyme Inhibitor, Fasting, Intermittent, Angiotensin Hypertension
    View official trial listing →
  • Status unknown NCT NCT04485845

    Metformin Versus Vildagliptin in Reducing Risk of Metabolic Syndrome Complications Progression

    Not yet reported Cairo University 39 participants Est. completion 2020-09-30 1 site Stand-alone
    Metabolic syndrome Other conditions: Diabete Type 2, Kidney Insufficiency
    View official trial listing →
  • Completed NCT NCT04489147

    Effect of Metformin on Non PCO Women Undergoing IVF/ICSI

    Not yet reported Kasr El Aini Hospital 400 participants Est. completion 2020-11-27 1 site
    Other conditions: Infertility
    View official trial listing →
  • Completed NCT NCT04497792

    Safety and Efficacy of Empagliflozin for Patients With Diabetes Mellitus and Planned Percutaneous Coronary Interventions

    Not yet reported Research Institute for Complex Problems of Cardiovascular Diseases, Russia 40 participants Est. completion 2019-11
    Cardiovascular disease Other conditions: Diabetes Mellitus, Percutaneous Coronary Intervention
    View official trial listing →
  • Status unknown NCT NCT04502303

    18F-FDG and 68Ga-FAPI PET/CT in Crohn's Disease

    Not yet reported Peking Union Medical College Hospital 30 participants Est. completion 2021-09 Stand-alone
    Other conditions: Crohn Disease
    View official trial listing →
  • Terminated NCT NCT04504045

    Metformin's Effect on Drug Metabolism in Patients With Type 2 Diabetes

    Not yet reported University of Southern Denmark 10 participants Est. completion 2022-05-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04504396

    Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy

    Not yet reported PegBio Co., Ltd. 620 participants Est. completion 2023-05-26 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04508634

    Treating Obese PCOS Patients With LSG vs. Met

    Not yet reported Shanghai 10th People's Hospital 90 participants Est. completion 2024-09-30 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04510194

    COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)

    Not yet reported University of Minnesota 1323 participants Est. completion 2022-12-14 7 sites Stand-alone
    Other conditions: Covid19, SARS-CoV Infection
    View official trial listing →
  • Active, not recruiting NCT NCT04511416

    Preventing Cognitive Decline with Metformin

    Not yet reported Garvan Institute of Medical Research 242 participants Est. completion 2027-12 1 site
    Other conditions: Cognitive Decline
    View official trial listing →
  • Completed NCT NCT04521049

    Tubular Markers in Response to Saxagliptin Therapy

    Not yet reported Beni-Suef University 80 participants Est. completion 2020-04-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT04530058

    The Effects of Metformin on Morbidity and Mortality in Elderly Patients

    Not yet reported Hamilton Health Sciences Corporation 250 participants Est. completion 2029-03 1 site Stand-alone
    Other conditions: Burns
    View official trial listing →
  • Active, not recruiting NCT NCT04536805

    Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin

    Not yet reported, Not yet reported Institut Cancerologie de l'Ouest 44 participants Est. completion 2031-11 12 sites Stand-alone
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT04537923

    A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin

    Not yet reported Eli Lilly and Company 1428 participants Est. completion 2022-11-01 135 sites
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04545736

    Oral Metformin for Treatment of ABCA4 Retinopathy

    Not yet reported, Not yet reported National Eye Institute (NEI) 55 participants Est. completion 2029-02-02 2 sites Stand-alone
    Other conditions: ABCA4 Retinopathy, Stargardt Disease, Retinal Dystrophy, Retinal Degeneration
    View official trial listing →
  • Completed NCT NCT04549415

    The Influence of Metformin on Chronic Heart Failure Clinical Course in Patients With Prediabetes

    Not yet reported National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov 97 participants Est. completion 2019-11-15 1 site
    Heart failureCardiovascular diseasePrediabetes
    View official trial listing →
  • Status unknown NCT NCT04559308

    The Effect of Metformin on Breast Cancer Patients

    Not yet reported Beni-Suef University 80 participants Est. completion 2020-10 1 site Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT04566718

    A Treatment Legacy Effect of Metformin in Obese Women With PCOS

    University Medical Centre Ljubljana 40 participants Est. completion 2020-02-01 1 site
    Other conditions: PCOS
    View official trial listing →
  • Withdrawn NCT NCT04569214

    The Efficacy and Safety of PAZ320 on PPG and Insulin Blood Levels in Type II Diabetic Patients

    Not yet reported Boston Therapeutics Est. completion 2013-02 1 site
    Other conditions: Type II Diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04576104

    Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer

    Not yet reported Northwestern University 51 participants Est. completion 2026-06-30 8 sites Stand-alone
    Other conditions: Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, Endometrial Carcinoma
    View official trial listing →
  • Active, not recruiting NCT NCT04583462

    Impact of Metformin on Peripheral Arterial Calcification in Type 1 Diabetes

    Not yet reported Assistance Publique - Hôpitaux de Paris 230 participants Est. completion 2027-10-29 1 site Stand-alone
    Other conditions: Type 1 Diabetes, Peripheral Arterial Calcification
    View official trial listing →
  • Completed NCT NCT04588259

    Research Study to Compare a New Medicine "Fast-acting Insulin Aspart" to Another Medicine "Insulin Aspart" in Chinese People With Diabetes

    Not yet reported Novo Nordisk A/S 331 participants Est. completion 2022-08-05 40 sites Stand-alone
    Type 2 diabetes Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT04591626

    A Study of Dulaglutide (LY2189265) in Chinese Participants With Type 2 Diabetes

    Not yet reported Eli Lilly and Company 291 participants Est. completion 2022-04-28 27 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04593459

    Probiotic Intervention in PCOS

    Not yet reported Medical University of Graz 112 participants Est. completion 2023-10-16 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04596631

    A Research Study to Compare a New Medicine Oral Semaglutide to a Dummy Medicine in Children and Teenagers With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 132 participants Est. completion 2026-02-03 97 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT04607252

    Metformin Plus Megestrol Acetate As a Fertility-sparing Treatment in Patients with Atypical Endometrial Hyperplasia

    Not yet reported, Not yet reported Fudan University 12 participants Est. completion 2021-06-03 1 site Stand-alone
    Other conditions: Atypical Endometrial Hyperplasia
    View official trial listing →
  • Status unknown NCT NCT04615351

    A Pragmatic Approach to Lowering the Risk of Diabetes Mellitus After A Diagnosis of Gestational Diabetes Mellitus

    Not yet reported Women and Infants Hospital of Rhode Island 200 participants Est. completion 2022-06-30 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT04617275

    A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY

    Not yet reported Pfizer 151 participants Est. completion 2021-11-17 38 sites
    Other conditions: Diabetes, Obesity
    View official trial listing →
  • Status unknown NCT NCT04621656

    Sugar Challenge Study

    January, Inc. 1022 participants Est. completion 2021-10 1 site
    Type 2 diabetesPrediabetes Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT04621669

    Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 36 participants Est. completion 2021-09-08 1 site Stand-alone
    Other conditions: Drug-drug Interaction,SHR3680
    View official trial listing →
  • Completed NCT NCT04622111

    Safety and Pharmacokinetics Study of CPL207280 Compound in Healthy Volunteers.

    Not yet reported Celon Pharma SA 68 participants Est. completion 2021-05-05 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT04623567

    Efficacy Assessment of Chinese Herbal Medicine Jiangtang Tiaozhi Recipe Treating Participants With Glucose and Lipid Metabolism Disturbances

    Not yet reported, Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 96 participants Est. completion 2024-06-30 1 site
    Type 2 diabetes Other conditions: Dyslipidemias
    View official trial listing →
  • Completed NCT NCT04625946

    Metformin as an Adjunctive Therapy to Catheter Ablation in Atrial Fibrillation

    Not yet reported University of Michigan 117 participants Est. completion 2025-08-10 1 site Stand-alone
    Other conditions: Atrial Fibrillation
    View official trial listing →
  • Completed NCT NCT04625985

    Metformin Glycinate, Treatment of Patients With COVID-19 and Severe Acute Respiratory Syndrome Secondary to SARS-CoV-2.

    Not yet reported Laboratorios Silanes S.A. de C.V. 20 participants Est. completion 2021-03-18 1 site Stand-alone
    Other conditions: Severe Acute Respiratory Syndrome Coronavirus 2
    View official trial listing →
  • Withdrawn NCT NCT04626089

    Metformin Glycinate in Patients With MS or DM2 , Hospitalized With COVID-19 and SARS Secondary to SARS-CoV-2

    Not yet reported Laboratorios Silanes S.A. de C.V. Est. completion 2021-02 1 site Stand-alone
    Metabolic syndromeType 2 diabetes Other conditions: Severe Acute Respiratory Syndrome Coronavirus 2
    View official trial listing →
  • Status unknown NCT NCT04626323

    Randomized Study Comparing Metabolic Surgery With Intensive Medical Therapy to Treat Diabetic Kidney Disease

    Not yet reported Hospital Alemão Oswaldo Cruz 60 participants Est. completion 2024-12 1 site Stand-alone
    Type 2 diabetes Other conditions: Kidney Disease, Chronic, Kidney Injury
    View official trial listing →
  • Completed NCT NCT04631289

    Preadmission Metformin Exposure and Incidence of Acute Kidney Injury

    Second Affiliated Hospital of Guangzhou Medical University 3841 participants Est. completion 2020-11-10 1 site
    Other conditions: AKI
    View official trial listing →
  • Completed NCT NCT04634890

    Bialystok Exercise Study in Diabetes

    Not yet reported Medical University of Bialystok 300 participants Est. completion 2023-12-20 1 site
    Type 2 diabetesPrediabetes Other conditions: Overweight, Obesity, Dyslipidemias
    View official trial listing →
  • Completed NCT NCT04639492

    Postbiotic MBS and Metformin Combination in Patients With T2DM

    Not yet reported Microbio Co Ltd 14 participants Est. completion 2022-09-23 1 site
    Other conditions: Type-II Diabetes
    View official trial listing →
  • Completed NCT NCT04640571

    Impact of Metformin and Polysorbate 80 on Drug Absorption and Disposition

    Not yet reported University of Maryland, Baltimore 18 participants Est. completion 2021-11-01 1 site Stand-alone
    Other conditions: Bile Salt Export Pump (BSEP) Transporter, Polysorbate 80
    View official trial listing →
  • Completed NCT NCT04649502

    Metformin for the Treatment of Hidradenitis Suppurativa (HS)

    Not yet reported K.R. van Straalen 62 participants Est. completion 2023-08-23 1 site Stand-alone
    Other conditions: Hidradenitis Suppurativa
    View official trial listing →
  • Status unknown NCT NCT04653779

    A Clinical Trial to Evaluate the Preference Regarding Convenience of Medication and Efficacy/Safety of SUGAMET®XR Tablet 5/1000mg

    Not yet reported Dong-A ST Co., Ltd. 54 participants Est. completion 2021-07 2 sites Stand-alone
    Type 2 diabetes Other conditions: Renal Disease, Diabetes Mellitus, Metabolic Disease, Endocrine System Diseases
    View official trial listing →
  • Completed NCT NCT04654676

    DPP4 Inhibitor on Glycemic Variability

    Not yet reported University Malaysia Sarawak 12 participants Est. completion 2019-08-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04659915

    Counteracting Deleterious Metabolic Glucocorticoid Effects With Metformin

    Not yet reported Eleonora Seelig 19 participants Est. completion 2021-08-18 1 site Stand-alone
    Other conditions: Glucocorticoid Effect
    View official trial listing →
  • Withdrawn NCT NCT04662164

    A Study to Access the Efficacy in Type 2 Diabetes Mellitus on Stable Metformin

    Not yet reported, Not yet reported Shanghai HEP Pharmaceutical Co., Ltd. Est. completion 2025-12
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04662866

    Effects of Glucose Lowering Agents in South Asian Women With Impaired Glucose Tolerance or Impaired Fasting Glucose

    Not yet reported Oslo University Hospital 64 participants Est. completion 2023-10 1 site
    Prediabetes Other conditions: Insulin Sensitivity, Glucose Metabolism Disorders
    View official trial listing →
  • Completed NCT NCT04665570

    A Study to Learn More About How Acarbose and Metformin Work When Taken Together and How Safe They Are in Indian Patients Who Were Recently Diagnosed With Type 2 Diabetes (T2D)

    Bayer 2000 participants Est. completion 2024-09-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04667143

    Dual Add-on Therapy in Type 2 Diabetes Poorly Controlled With Metformin Monotherapy

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 760 participants Est. completion 2022-10 Stand-alone
    Other conditions: Diabetes Mellitus, Type II
    View official trial listing →
  • Completed NCT NCT04671953

    Effect of BMS-986165 on the Blood Levels of Metformin

    Not yet reported Bristol-Myers Squibb 36 participants Est. completion 2021-03-30 1 site Stand-alone
    Other conditions: Healthy Participants
    View official trial listing →
  • Status unknown NCT NCT04672031

    Glycemic Targets for Pregnant Women With GDM and T2DM

    Not yet reported University of Southern California 120 participants Est. completion 2023-07 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabetes Mellitus in Pregnancy, Diabetes, Gestational
    View official trial listing →
  • Completed NCT NCT04684420

    GXR RM (Glucophage® Extended Release Reduced Mass) 500 Milligram (mg) Korea Bioequivalence (BE) Study

    Not yet reported Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 81 participants Est. completion 2022-03-11 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Active, not recruiting NCT NCT04691960

    A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging

    Not yet reported Weill Medical College of Cornell University 18 participants Est. completion 2026-06 2 sites Stand-alone
    Other conditions: Glioblastoma
    View official trial listing →
  • Completed NCT NCT04700839

    SGLT2 Inhibitors in Patients With PCOS

    Not yet reported Shanghai 10th People's Hospital 68 participants Est. completion 2021-04-30 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04706377

    Vitamin B12 Supplementation in Diabetic Neuropathy

    Not yet reported Aristotle University Of Thessaloniki 90 participants Est. completion 2020-02-28 1 site
    Other conditions: Diabetes Mellitus, Diabetic Neuropathies, Diabetic Complication, Diabetic Foot
    View official trial listing →
  • Completed NCT NCT04738799

    The Impact of Food Order on Glycemic Excursions in Type 2 Diabetes Assessed by Continuous Glucose Monitoring

    Not yet reported Weill Medical College of Cornell University 20 participants Est. completion 2023-07-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT04741204

    Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer

    Not yet reported Woman's Est. completion 2022-09 1 site Stand-alone
    Other conditions: Breast Cancer Stage, Insulin Resistance, Racial Bias
    View official trial listing →
  • Active, not recruiting NCT NCT04742751

    An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer

    Not yet reported St. Jude Children's Research Hospital 96 participants Est. completion 2027-03 1 site Stand-alone
    Prediabetes Other conditions: Adult Children
    View official trial listing →
  • Status unknown NCT NCT04750135

    Assessment of Metformin as Adjuvant Therapy in Patients With Ulcerative Colitis

    Not yet reported National Hepatology & Tropical Medicine Research Institute 40 participants Est. completion 2021-06-01 1 site Stand-alone
    Other conditions: Ulcerative Colitis, Inflammatory Bowel Diseases
    View official trial listing →
  • Terminated NCT NCT04754334

    A Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus

    Not yet reported Oramed, Ltd. 346 participants Est. completion 2023-01-13 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04762966

    Study of Metformin Overdose

    Central Hospital, Nancy, France 50 participants Est. completion 2021-09-01 1 site
    Other conditions: Metformin Associated Lactic Acidosis
    View official trial listing →
  • Status unknown NCT NCT04766008

    Metformin in Diabetic Patients Undergoing Coronary Angiography

    Not yet reported Humanitas Hospital, Italy 150 participants Est. completion 2022-04-30 1 site Stand-alone
    Cardiovascular disease Other conditions: Diabetes Mellitus, Lactic Acidosis With Diabetes Mellitus, Contrast-induced Nephropathy, Metformin Associated Lactic Acidosis
    View official trial listing →
  • Withdrawn NCT NCT04767841

    The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis

    Not yet reported, Not yet reported Sadat City University Est. completion 2024-12-31 1 site Stand-alone
    Other conditions: Osteo Arthritis Knee
    View official trial listing →
  • Status unknown NCT NCT04780854

    Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN)

    Not yet reported Cairo University 68 participants Est. completion 2022-07 1 site
    Other conditions: Chemotherapy-induced Peripheral Neuropathy
    View official trial listing →
  • Status unknown NCT NCT04792749

    Clinical Effects of Metformin on Fertility-sparing Treatment for Early Endometrial Cancer

    Not yet reported Samsung Medical Center 77 participants Est. completion 2024-03-31 1 site Stand-alone
    Other conditions: Endometrial Cancer Stage I
    View official trial listing →
  • Status unknown NCT NCT04796428

    GliflOzin in eLderly Diabetic patiENts: A praGmatic Intraclass Evaluation Trial

    Not yet reported Center for Outcomes Research and Clinical Epidemiology, Italy 1167 participants Est. completion 2023-12-31
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04799938

    Effect of Exercise on GDF-15 Levels in Prediabetic Patients

    Not yet reported Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey 70 participants Est. completion 2023-04-01 1 site
    Prediabetes
    View official trial listing →
  • Completed NCT NCT04807348

    Chiglitazar Added to Metformin for Type 2 Diabetes

    Not yet reported Chipscreen Biosciences, Ltd. 533 participants Est. completion 2023-02-10 50 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04809311

    Remote Study Collecting Blood Glucose Values and Activity Data in Patients With Type 2 Diabetes on Different Treatments

    Novo Nordisk A/S 156 participants Est. completion 2025-01-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04817215

    Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus

    Not yet reported King Hamad University Hospital, Bahrain 608 participants Est. completion 2022-07 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04826692

    TEsting METformin Against Cognitive Decline in HD

    Not yet reported Instituto de Investigacion Sanitaria La Fe 60 participants Est. completion 2025-06-10 9 sites Stand-alone
    Other conditions: Huntington Disease
    View official trial listing →
  • Completed NCT NCT04829903

    Dulaglutide Versus Liraglutide in Obese Type 2 Diabetic Adolescents Using Metformin

    Not yet reported Corporacion Parc Tauli 116 participants Est. completion 2021-11-20 1 site
    Type 2 diabetes Other conditions: Obesity, Adolescent Obesity
    View official trial listing →
  • Not yet recruiting NCT NCT04836910

    Microbiome and Polycystic Ovaries

    Sheba Medical Center 40 participants Est. completion 2027-03-30 1 site
    Other conditions: Polycystic Ovary Syndrome, Microbial Colonization
    View official trial listing →
  • Withdrawn NCT NCT04839237

    The Effect and the Pharmacogenomics Study of Liraglutide in Obese Patients

    Not yet reported Xiangya Hospital of Central South University Est. completion 2021-12-01 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT04841096

    Oral Combination of Glimepiride/Vildagliptin/Metformin in Patients With T2D and Dual Treatment Failure

    Not yet reported Laboratorios Silanes S.A. de C.V. 162 participants Est. completion 2024-05-15 5 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT04841668

    Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly

    Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta 50 participants Est. completion 2024-12-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04850846

    Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma

    Not yet reported Dana-Farber Cancer Institute 60 participants Est. completion 2027-07-31 7 sites Stand-alone
    Other conditions: Monoclonal Gammopathy of Undetermined Significance, Smoldering Multiple Myeloma
    View official trial listing →
  • Completed NCT NCT04852510

    Amelioration of Polycystic Ovary Syndrome Related Disorders by Supplementation of Thymoquinone and Metformin

    Not yet reported, Not yet reported Saudi German Hospital - Madinah 253 participants Est. completion 2020-08-31 1 site
    Other conditions: Polycystic Ovary Syndrome (PCOS)
    View official trial listing →
  • Suspended NCT NCT04854512

    Investigational Study of Delayed Release Metformin

    Not yet reported Anji Pharma 675 participants Est. completion 2024-06-30 87 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04855513

    Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial

    Not yet reported Hamad Medical Corporation 414 participants Est. completion 2023-12-30 1 site Stand-alone
    Other conditions: Preeclampsia, Preeclampsia Severe, High Risk Pregnancy, Eclampsia
    View official trial listing →
  • Completed NCT NCT04856007

    A Study to Assess the Bioequivalence of Fixed Dose Combination of Dapagliflozin/Metformin XR Relative to Co-administration of the Individual Components in Healthy Chinese Subjects.

    Not yet reported AstraZeneca 80 participants Est. completion 2021-06-14 1 site Stand-alone
    Other conditions: Healthy Volunteer
    View official trial listing →
  • Completed NCT NCT04859452

    A Study to Evaluate the DDI of DBPR108 With Metformin,Glibenclamide,Valsartan, or Simvastatin in Healthy Subjects

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 56 participants Est. completion 2021-07-09 1 site Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT04862390

    Incidence of Hypoglycemia in Pregnant Ladies With or Without Gestational Diabetes Fasting Ramadan

    King Abdullah International Medical Research Center 30 participants Est. completion 2021-08-01 1 site
    Other conditions: Pregnancy in Diabetic
    View official trial listing →
  • Completed NCT NCT04865835

    A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia.

    Not yet reported Otsuka Pharmaceutical Development & Commercialization, Inc. 21 participants Est. completion 2022-05-03 2 sites Stand-alone
    Other conditions: Schizophrenia
    View official trial listing →
  • Completed NCT NCT04866667

    Observational Study of ASCVD Risks of Type 2 Diabetes in East China

    Zhejiang Provincial People's Hospital 316 participants Est. completion 2024-05-31 1 site
    Type 2 diabetesCardiovascular disease Other conditions: Liraglutide
    View official trial listing →
  • Completed NCT NCT04867252

    Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian Syndrome

    Not yet reported Khyber Medical University Peshawar 88 participants Est. completion 2021-08-03 1 site
    Other conditions: PCOS
    View official trial listing →
  • Active, not recruiting NCT NCT04869917

    Behavioral Nudges for Diabetes Prevention (BEGIN) Trial in Primary Care

    Not yet reported Northwestern University 960 participants Est. completion 2026-09-01 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Completed NCT NCT04877106

    Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects

    Not yet reported The Affiliated Hospital of Qingdao University 48 participants Est. completion 2018-07-31 1 site Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT04879511

    Effect of Metformin in Children With Type 1 Diabetes

    Not yet reported, Not yet reported Ain Shams University 80 participants Est. completion 2021-01-29 1 site
    Other conditions: Effect of Change in T1DM Glycemic Control
    View official trial listing →
  • Status unknown NCT NCT04882332

    Metformin Usage Index and Vitamin B12 Status in Egyptian Type 2 Diabetic Patients

    Cairo University 108 participants Est. completion 2022-10 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT04885426

    Metformin for the Prevention of CRA Recurrence

    Not yet reported Jing-yuan Fang, MD, Ph. D 414 participants Est. completion 2022-11 1 site Stand-alone
    Other conditions: Colorectal Adenoma, Metformin, Chemoprevention
    View official trial listing →
  • Completed NCT NCT04885530

    ACTIV-6: COVID-19 Study of Repurposed Medications

    Not yet reported Susanna Naggie, MD 10956 participants Est. completion 2024-04-29 110 sites Stand-alone
    Other conditions: Covid19
    View official trial listing →
  • Completed NCT NCT04885712

    A Study to Evaluate the Efficacy and Safety of Pioglitazone 15mg or 30mg Add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin

    Not yet reported Boryung Pharmaceutical Co., Ltd 378 participants Est. completion 2023-03-10 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT04893148

    Efficacy and Safety of iGlarLixi Versus Insulin Glargine Plus Dulaglutide in Patients With Type 2 Diabetes

    Not yet reported Chungbuk National University Hospital 40 participants Est. completion 2022-12-30 1 site
    Type 2 diabetes Other conditions: Glucose, High Blood
    View official trial listing →
  • Active, not recruiting NCT NCT04897945

    A Shared Decision Making Intervention for Diabetes Prevention in Women With a History of Gestational Diabetes Mellitus

    Not yet reported University of California, Los Angeles 310 participants Est. completion 2026-10-01 2 sites Stand-alone
    PrediabetesType 2 diabetes Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT04899349

    Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and Fulvestrant

    Not yet reported Novartis Pharmaceuticals 2 participants Est. completion 2023-05-10 2 sites Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT04902326

    Behavioral Economics and Self-Determination Theory to Change Diabetes Risk (BEST Change)

    Not yet reported University of Michigan 380 participants Est. completion 2023-09-18 1 site Stand-alone
    Other conditions: Pre Diabetes
    View official trial listing →
  • Completed NCT NCT04907708

    Comparative Effects of Metformin and Insulin on Stereological Studies and Immunohistochemistry of Placenta

    Not yet reported University of Karachi 156 participants Est. completion 2019-08-07 1 site Stand-alone
    Other conditions: Diabetes Mellitus Arising in Pregnancy, Insulin-Requiring, Diabetes Mellitus in Pregnancy
    View official trial listing →
  • Completed NCT NCT04916093

    Safety and Efficacy of Antidiabetic Drugs in Recently Diagnosed Patients With Type 2 Diabetes

    Not yet reported Beni-Suef University 60 participants Est. completion 2020-12-15 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT04925063

    The Effect of Metformin in Patients With Newly Diagnosed mHSPC

    Not yet reported Sun Yat-sen University 266 participants Est. completion 2027-01-31 1 site Stand-alone
    Other conditions: Metastatic Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT04926155

    The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer

    Not yet reported Sun Yat-sen University 234 participants Est. completion 2024-08-31 1 site Stand-alone
    Other conditions: Metastatic Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT04930471

    Steroid and Behaviour Changes Under Metformin

    Insel Gruppe AG, University Hospital Bern 45 participants Est. completion 2023-12 1 site
    Other conditions: Autistic Disorder
    View official trial listing →
  • Completed NCT NCT04930744

    Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)

    Not yet reported University of Massachusetts, Worcester 112 participants Est. completion 2025-08-15 2 sites Stand-alone
    Other conditions: Tuberculosis, Pulmonary Tuberculosis, HIV Coinfection
    View official trial listing →
  • Active, not recruiting NCT NCT04931017

    Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer

    Not yet reported Northwestern University 50 participants Est. completion 2027-06-30 4 sites Stand-alone
    Other conditions: Lung Carcinoma
    View official trial listing →
  • Completed NCT NCT04931147

    A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers

    Not yet reported Redx Pharma Ltd 90 participants Est. completion 2023-03-08 1 site Stand-alone
    Other conditions: Fibrosis, Inflammation, Idiopathic Pulmonary Fibrosis, Non-alcoholic Steatohepatitis, Liver Diseases, Kidney Diseases
    View official trial listing →
  • Completed NCT NCT04947020

    DataBase for Analysis of Rectal Cancer Oncological Results

    Jagiellonian University 2443 participants Est. completion 2024-12-31 1 site
    Other conditions: Rectal Cancer, Metformin, Overall Survival, Lymph Node Metastases, Disease-free Survival
    View official trial listing →
  • Status unknown NCT NCT04962841

    Nutraceuticals and Drug Treatment in Frail Older Adults

    University of Campania Luigi Vanvitelli 485 participants Est. completion 2023-04-01 1 site
    Other conditions: Frailty
    View official trial listing →
  • Completed NCT NCT04969627

    Effects of GLP-1 Analogue Combined With Metformin and Metformin on Gonadal and Metabolic Profiles in Chinese Overweight/Obese PCOS Patients With Hyperandrogenemia.

    Not yet reported Bing He 60 participants Est. completion 2022-03-29 1 site Mixed
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04972396

    Pemvidutide (ALT-801) DDI Study in Healthy Volunteers

    Not yet reported Altimmune, Inc. 40 participants Est. completion 2022-05-15 2 sites Stand-alone
    MASH
    View official trial listing →
  • Completed NCT NCT04973891

    CANA/Met in Non-diabetic Women With PCOS

    Not yet reported, Not yet reported Shengjing Hospital 52 participants Est. completion 2022-03-08 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT04976283

    Effect of Oral Anti-diabetic Medication on Liver Fat in Subjects With Type II Diabetes and Non-alcoholic Fatty Liver

    Not yet reported Getz Pharma 123 participants Est. completion 2023-11-15 1 site
    Type 2 diabetesMASHMASLD
    View official trial listing →
  • Completed NCT NCT04979130

    Comparing Semaglutide Versus Placebo on Intestinal Barrier Function in Type 2 Diabetes Mellitus (SIB)

    Not yet reported University of Colorado, Denver 69 participants Est. completion 2024-10-16 1 site Added to GLP-1
    Type 2 diabetes Other conditions: Chronic Inflammation, Intestinal Permeability
    View official trial listing →
  • Status unknown NCT NCT04984070

    Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety

    Not yet reported Fudan University 100 participants Est. completion 2024-12-31 1 site Stand-alone
    Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety
    View official trial listing →
  • Withdrawn NCT NCT04994561

    VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements

    Not yet reported Vitality in Aging Research Group, Inc. Est. completion 2023-12 Stand-alone
    Other conditions: Aging
    View official trial listing →
  • Completed NCT NCT04998032

    A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment(SUPER-2)

    Not yet reported, Not yet reported Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. 620 participants Est. completion 2023-08-13 61 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05004948

    Exercise Intervention Combined With Metformin in the Treatment of Type 2 Diabetes

    Not yet reported Prince Sattam Bin Abdulaziz University 57 participants Est. completion 2019-10-15 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05013112

    Ameliorating Metabolic Profiling After Kidney Transplantation (AMPKT)

    Not yet reported West China Hospital 105 participants Est. completion 2025-12-31 1 site Stand-alone
    Other conditions: Kidney Transplantation, Metabolic Disorder, Metformin, Empagliflozin
    View official trial listing →
  • Completed NCT NCT05025852

    The Effect of In-utero Exposure to Metformin in 5-11 Year Old Offspring of Mothers in the MiTy Trial

    Mount Sinai Hospital, Canada 132 participants Est. completion 2025-04-30 12 sites
    Type 2 diabetes Other conditions: Pregnancy in Diabetic, Child Obesity, Child Development
    View official trial listing →
  • Status unknown NCT NCT05032001

    ORAL ANTIDIABETICS EFFECT ON VISCERAL FAT

    Not yet reported Metabolic Research Unit 30 participants Est. completion 2022-08-01 1 site Stand-alone
    Type 2 diabetes Other conditions: Abdominal Obesity
    View official trial listing →
  • Completed NCT NCT05035082

    A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE)

    Not yet reported Novo Nordisk A/S 1018 participants Est. completion 2025-06-18 25 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT05040087

    Changing the Natural History of Type 2 Diabetes ("CHANGE" Study)

    Not yet reported Foundation for Atlanta Veterans Education and Research, Inc. 127 participants Est. completion 2028-06-30 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05041673

    Anti-diabetic Drugs and Fatty Liver Management

    Not yet reported Alexandria University 120 participants Est. completion 2022-09-30 1 site Stand-alone
    Type 2 diabetes Other conditions: Fatty Liver, Nonalcoholic
    View official trial listing →
  • Completed NCT NCT05042505

    Effect of Dapagliflozin vs Sitagliptin on Liver Fat Accumulation and Body Composition in Patients With Diabetes Mellitus and Liver Transplantation

    Not yet reported Medanta, The Medicity, India 100 participants Est. completion 2026-02-27 1 site
    Other conditions: Diabetes Mellitus, Liver Transplant; Complications
    View official trial listing →
  • Status unknown NCT NCT05052918

    The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes

    Not yet reported Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey 90 participants Est. completion 2023-03-15 1 site
    Other conditions: Pre Diabetes, Exercise, Metformin, Atherosclerosis
    View official trial listing →
  • Completed NCT NCT05053841

    Implication of Metformin Plus Aromatase Inhibitor in Obese Postmenopausal Breast Cancer Women

    Not yet reported Tanta University 45 participants Est. completion 2015-06
    Other conditions: Metformin, Breast Cancer
    View official trial listing →
  • Status unknown NCT NCT05054842

    Clinical Study of Retagliptin Phosphate Combined With Metformin in the Treatment of Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 174 participants Est. completion 2023-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05055219

    Conventional and Metabolomic Predictors of Prediabetes & Insulin Resistance

    University of Michigan 772 participants Est. completion 2020-02-19 1 site
    Prediabetes Other conditions: Obesity, Childhood
    View official trial listing →
  • Completed NCT NCT05081583

    Clinical Evaluation of the Pharmacokinetic Goldenseal-Metformin Interaction in Diabetic Patients

    Not yet reported Washington State University 22 participants Est. completion 2023-08-31 1 site Stand-alone
    Type 2 diabetes Other conditions: Interaction, Adverse Herb-Drug
    View official trial listing →
  • Completed NCT NCT05083949

    A Study in Healthy Humans to Assess the Relative Bioavailability of One Fixed-dose Combination Tablet Empagliflozin/Metformin Versus Jardiance® Tablet and Glifage® Tablet Administered Together

    Not yet reported Boehringer Ingelheim 32 participants Est. completion 2021-09-09 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05093959

    Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction

    Not yet reported Wake Forest University Health Sciences 86 participants Est. completion 2026-04-16 2 sites
    Heart failure
    View official trial listing →
  • Active, not recruiting NCT NCT05098470

    Effects of Modulators of Gluconeogenesis, Glycogenolysis and Glucokinase Activity

    Not yet reported University of Alabama at Birmingham 100 participants Est. completion 2026-07-29 2 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05101135

    To Evaluate the Efficacy and Safety of JT-001 add-on in Paatients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin

    Not yet reported Jeil Pharmaceutical Co., Ltd. 256 participants Est. completion 2022-10-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT05102071

    Clinical Outcomes and Healthcare Cost and Resource Utilization (HCRU) in Patients With Type 2 Diabetes and Cardiovascular Disease on 2nd Line Empagliflozin Versus 2nd Line Sulfonylureas

    Boehringer Ingelheim Est. completion 2022-06-15 1 site
    Type 2 diabetesCardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT05103306

    Empagliflozin-based Quadruple Therapy vs Basal Insulin-based Therapy

    Chungbuk National University Hospital 300 participants Est. completion 2022-12
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05108350

    A Study to Assess the Bioequivalence of Fixed Dose Combination of HR20033 Relative to Co-administration of the Individual Components in Healthy Chinese Subjects

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 80 participants Est. completion 2021-12-10 Stand-alone
    Other conditions: Type II Diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT05109169

    METformin and FINGER Intervention to Prevent Cognitive Impairment and Disability in Older Adults at Risk for Dementia

    Not yet reported Imperial College London 600 participants Est. completion 2028-06-30 3 sites
    Other conditions: Cognitive Decline, Cognitive Impairment, Dementia
    View official trial listing →
  • Completed NCT NCT05120505

    Metformin in Children With Fragile X Syndrome

    Not yet reported Children's Hospital of Fudan University 37 participants Est. completion 2025-01-30 1 site Stand-alone
    Other conditions: Fragile X Syndrome, Metformin
    View official trial listing →
  • Completed NCT NCT05123781

    Fasting Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers

    Not yet reported Joint Stock Company "Farmak" 28 participants Est. completion 2019-04-17 1 site Stand-alone
    Other conditions: Pharmacokinetics
    View official trial listing →
  • Completed NCT NCT05124717

    Fed Bioequivalence Study of 2 Metformin 500 mg Prolongued Release Tablets in 28 Healthy Male and Female Volunteers

    Not yet reported Joint Stock Company "Farmak" 28 participants Est. completion 2019-07-03 1 site Stand-alone
    Other conditions: Pharmacokinetics
    View official trial listing →
  • Completed NCT NCT05124730

    Fasting Bioequivalence Study of 2 Metformin 500 mg Prolonged Release Tablets in 44 Healthy Male and Female Volunteers

    Not yet reported Joint Stock Company "Farmak" 44 participants Est. completion 2021-05-29 1 site Stand-alone
    Other conditions: Pharmacokinetics
    View official trial listing →
  • Completed NCT NCT05125575

    Fed Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers

    Not yet reported Joint Stock Company "Farmak" 28 participants Est. completion 2019-01-19 1 site Stand-alone
    Other conditions: Pharmacokinetics
    View official trial listing →
  • Status unknown NCT NCT05126381

    Population Pharmacokinetic - Pharmacodynamic Models of Chronic Disease Therapeutics for Smokers

    The Second Affiliated Hospital of Chongqing Medical University 200 participants Est. completion 2024-04-30 1 site
    Other conditions: Chronic Disease, Smoking
    View official trial listing →
  • Completed NCT NCT05131828

    CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy

    Not yet reported Cambridge University Hospitals NHS Foundation Trust 70 participants Est. completion 2025-09-26 1 site Stand-alone
    Other conditions: Multiple Sclerosis
    View official trial listing →
  • Completed NCT NCT05132023

    Bioequivalence Study of Empagliflozin & Metformin HCL From Empagliform 12.5/1000 mg F.C.T (Hikma Pharma, Egypt) and Synjardy 12.5/1000 mg F.C.T (Boehringer Ingelheim International GmbH, Germany)

    Not yet reported Genuine Research Center, Egypt 26 participants Est. completion 2019-05-15 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT05147896

    Semaglutide Anti-Atherosclerotic Mechanisms of Action Study in Type 2 Diabetes Patients

    Not yet reported University Medical Centre Ljubljana 100 participants Est. completion 2023-12-01 1 site
    Type 2 diabetes Other conditions: Atherosclerosis
    View official trial listing →
  • Completed NCT NCT05151146

    A Phase 1 Study of ANJ900 Chinese Healthy Subjects

    Not yet reported Anji Pharma 18 participants Est. completion 2022-02-28 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Withdrawn NCT NCT05158374

    Molecular Effects of Aspirin & Metformin on Colonic Epithelium

    Not yet reported University of Edinburgh Est. completion 2023-06
    Other conditions: Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenoma
    View official trial listing →
  • Status unknown NCT NCT05161429

    BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes

    Brigham and Women's Hospital 550000 participants Est. completion 2024-06-30 5 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05162014

    To Assess the Risk of Acute Pancreatitis in Patients With Type 2 Diabetes Mellitus Treated With Empagliflozin

    Boehringer Ingelheim 494679 participants Est. completion 2022-09-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05162690

    Efficacy of Dapagliflozin in Diabetes Associated Peripheral Neuropathy

    Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 40 participants Est. completion 2023-12-31 1 site
    Other conditions: Diabetic Peripheral Neuropathy
    View official trial listing →
  • Completed NCT NCT05164523

    The Effect of SGLT2 Inhibitors on Heart Rate Variability and BDNF Levels in Patients With Type 2 Diabetes

    Goztepe Training and Research Hospital 64 participants Est. completion 2022-12-30 1 site
    Type 2 diabetes Other conditions: Heart Rate Variability
    View official trial listing →
  • Completed NCT NCT05167513

    Monitoring Parameters Beyond Glycemic Control: Impact of Sitagliptin on Quality of Life in Type 2 Diabetes Patients

    Not yet reported Getz Pharma 188 participants Est. completion 2022-04-28 1 site Stand-alone
    Type 2 diabetes Other conditions: Quality of Life, Metformin+Sitagliptin
    View official trial listing →
  • Completed NCT NCT05177588

    Efficacy of Metformin as add-on Therapy in Non-Diabetic Heart Failure Patients

    Not yet reported Cairo University 70 participants Est. completion 2023-04-30 1 site Stand-alone
    Heart failure
    View official trial listing →
  • Status unknown NCT NCT05182970

    Metformin and Prevention of Cardiovascular Events in Patients With Acute Myocardial Infarction and Prediabetes (MIMET)

    Not yet reported Karolinska Institutet 5160 participants Est. completion 2026-05 1 site
    PrediabetesCardiovascular disease
    View official trial listing →
  • Suspended NCT NCT05183204

    Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma

    Not yet reported Weill Medical College of Cornell University 33 participants Est. completion 2026-06 1 site Stand-alone
    Other conditions: Glioblastoma
    View official trial listing →
  • Withdrawn NCT NCT05192850

    Endometrial Cancer Recurrence in Patients Taking Metformin

    WellSpan Health Est. completion 2023-02-27 1 site
    Other conditions: Recurrent Endometrial Carcinoma
    View official trial listing →
  • Status unknown NCT NCT05200793

    Efficacy of Empagliflozin or Linagliptin as an Alternative to Metformin for Treatment of Polycystic Ovary Syndrome

    Not yet reported Alexandria University 75 participants Est. completion 2022-09-01 1 site
    Other conditions: Polycystic Ovary Syndrome (PCOS)
    View official trial listing →
  • Status unknown NCT NCT05214235

    A Clinical Study on the Effect of Hypoglycemic Drugs on the Prognosis of Spinal Surgery in Diabetic Patients

    Xijing Hospital 124 participants Est. completion 2024-02-29 1 site
    Other conditions: Diabetes Mellitus, Spinal Diseases
    View official trial listing →
  • Active, not recruiting NCT NCT05220917

    Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study

    Brigham and Women's Hospital 781430 participants Est. completion 2027-09-30 1 site
    Type 2 diabetes Other conditions: Cardiovascular Events, Renal Disease
    View official trial listing →
  • Status unknown NCT NCT05226897

    Clinical Trial to Assess the Efficacy and Safety of YYC405 in Type 2 Diabetes Patients

    Not yet reported Yooyoung Pharmaceutical Co., Ltd. 256 participants Est. completion 2023-06-26 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05232994

    Metformin and Esomeprazole For Preterm Pre-eclampsia

    Not yet reported Christiana Care Health Services 38 participants Est. completion 2025-12-31 1 site Stand-alone
    Other conditions: Preeclampsia Severe, Preeclampsia Second Trimester, Preterm Birth Complication
    View official trial listing →
  • Completed NCT NCT05233514

    Effect of Aerobic Exercise on Polycystic Ovary Syndrome

    Not yet reported Cairo University 40 participants Est. completion 2021-12-10 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT05236530

    Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

    Not yet reported Novartis Pharmaceuticals 48 participants Est. completion 2022-10-17 1 site Stand-alone
    Other conditions: Malaria
    View official trial listing →
  • Active, not recruiting NCT NCT05237960

    Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia

    Not yet reported University of Arizona 34 participants Est. completion 2026-12 10 sites Stand-alone
    Other conditions: Erythroplakia, Oral Leukoplakia
    View official trial listing →
  • Completed NCT NCT05240274

    The POWERED Study: Prophylaxis With Metformin to Prevent PTDM

    Not yet reported Barts & The London NHS Trust 60 participants Est. completion 2022-08-30 1 site
    Other conditions: Post-transplant Diabetes Mellitus, New Onset Diabetes After Transplant, New Onset Diabetes After Transplantation, Kidney Transplant; Complications, Renal Transplantation, End Stage Renal Disease, Metformin
    View official trial listing →
  • Completed NCT NCT05260021

    A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both

    Not yet reported Eli Lilly and Company 99 participants Est. completion 2025-01-28 51 sites
    Type 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders, Endocrine System Diseases, Metabolic Disease
    View official trial listing →
  • Status unknown NCT NCT05261997

    Endotherapy for Painless Chronic Pancreatitis

    Not yet reported Changhai Hospital 60 participants Est. completion 2023-11 1 site
    Other conditions: Pancreatitis, Chronic, Exocrine Pancreatic Insufficiency, Abdominal Pain, Cholangiopancreatography, Endoscopic Retrograde
    View official trial listing →
  • Status unknown NCT NCT05262257

    Evaluation and Intervention of Cognitive Function in Patients With Diabetes Mellitus.

    Not yet reported The First Affiliated Hospital with Nanjing Medical University 120 participants Est. completion 2023-12-30 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT05275608

    Effects of VLCKD in Metabolic Syndrome

    Not yet reported Azienda Ospedaliero Universitaria Maggiore della Carita 40 participants Est. completion 2026-12 1 site Stand-alone
    Type 2 diabetesMetabolic syndrome Other conditions: Non-alcoholic Fatty Liver Disease, Obesity
    View official trial listing →
  • Completed NCT NCT05279768

    Stem Cells and Secretomes for Infertility Therapy in Polycystic Ovary Syndrome (PCOS) Patients With Insulin Resistance.

    Not yet reported, Not yet reported PT. Prodia Stem Cell Indonesia 44 participants Est. completion 2025-01-20 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT05280496

    A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes

    Not yet reported Tufts Medical Center 20 participants Est. completion 2025-04-18 1 site Stand-alone
    PrediabetesType 2 diabetes Other conditions: Diabetes, Gestational
    View official trial listing →
  • Completed NCT NCT05284344

    The Impact of Glucotoxicity on Gastric Emptying in Chinese Patients With Newly Diagnosed Type 2 Diabetes

    University of Adelaide 78 participants Est. completion 2023-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05288153

    Metformin Efficacy and Safety for Gastric Intestinal Metaplasia

    Not yet reported Xijing Hospital of Digestive Diseases 140 participants Est. completion 2023-10-31 2 sites Stand-alone
    Other conditions: Gastric Intestinal Metaplasia
    View official trial listing →
  • Status unknown NCT NCT05292573

    Longitudinal Follow-up in Women With Endometrial Hyperplasia Without Atypia

    Not yet reported Chang Gung Memorial Hospital 1000 participants Est. completion 2026-01-29 1 site Stand-alone
    Other conditions: Female
    View official trial listing →
  • Status unknown NCT NCT05296044

    To Evaluate the Efficacy and Safety of JT-003 add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin

    Not yet reported Jeil Pharmaceutical Co., Ltd. 245 participants Est. completion 2024-02-28 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05298670

    Drug Repurposing Using Metformin for Improving the Therapeutic Outcome in Multiple Sclerosis Patients

    Not yet reported German University in Cairo 80 participants Est. completion 2023-03-28 1 site Stand-alone
    Other conditions: Multiple Sclerosis
    View official trial listing →
  • Status unknown NCT NCT05305898

    "MetCool ACS"- Metformin "Cooling" Effect on Metformin-naive Patients Treated With PCI Because of Acute Coronary Syndrome

    Not yet reported Military Institute od Medicine National Research Institute 2000 participants Est. completion 2025-12 14 sites Stand-alone
    Other conditions: Acute Coronary Syndrome
    View official trial listing →
  • Active, not recruiting NCT NCT05306028

    Metformin and Insulin to Pancreatic Cancer Related Diabetes (Type 3c)

    Not yet reported Fudan University 20 participants Est. completion 2025-12-31 1 site Stand-alone
    Other conditions: Pancretic Cancer, Diabete Mellitus
    View official trial listing →
  • Completed NCT NCT05313529

    LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 396 participants Est. completion 2026-07-01 5 sites Mixed
    Type 2 diabetes Other conditions: Mild Cognitive Impairment
    View official trial listing →
  • Active, not recruiting NCT NCT05317806

    Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency

    Not yet reported Indiana Hemophilia &Thrombosis Center, Inc. 15 participants Est. completion 2027-10 1 site Stand-alone
    Other conditions: Plasminogen Activator Inhibitor-1 Deficiency, Cardiac Fibrosis
    View official trial listing →
  • Status unknown NCT NCT05326490

    Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients With Poor Glycemic Control Via Metformin Hydrochloride Monotherapy

    Not yet reported PegBio Co., Ltd. 546 participants Est. completion 2024-10-31 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05326984

    Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia

    Not yet reported Hospital General de Mexico 20 participants Est. completion 2023-12 1 site Stand-alone
    Other conditions: Acute Lymphoblastic Leukemia
    View official trial listing →
  • Completed NCT NCT05329857

    The Study Intends to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safety Profile of Test Product Compared to Reference Product Will be Evaluated.

    Not yet reported AET Laboratories Private Limited 60 participants Est. completion 2016-03 Stand-alone
    Other conditions: To Determine Bioequivalence Under Fed Conditions
    View official trial listing →
  • Completed NCT NCT05332795

    The Impact of Metformin on the Outcome of Gouty Arthritis in a Cohort of Egyptian Gouty Patients.

    Not yet reported Menoufia University 100 participants Est. completion 2024-02-20 1 site
    Other conditions: Gouty Arthritis
    View official trial listing →
  • Active, not recruiting NCT NCT05333003

    Semaglutide in Comorbid Schizophrenia Spectrum Disorder and Obesity

    Not yet reported Centre for Addiction and Mental Health 92 participants Est. completion 2026-08 1 site
    Other conditions: Schizophrenia Spectrum Disorders
    View official trial listing →
  • Status unknown NCT NCT05333835

    A Trial Comparing the Efficacy and Safety of HR17031 Injection to INS068 Injection and to SHR20004 Injection in Patients With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 455 participants Est. completion 2024-03-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05337969

    The Study Aims to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safety Profile of Test Product Compared to Reference Product Will be Assessed.

    Not yet reported AET Laboratories Private Limited 60 participants Est. completion 2016-03 Stand-alone
    Other conditions: To Determine Bioequivalence Under Fed Conditions
    View official trial listing →
  • Completed NCT NCT05343767

    Investigate the Efficacy and Safety of Low-Glu in Patients Newly Diagnosed With Type II Diabetes Mellitus

    Not yet reported Natural Wellness Egypt 198 participants Est. completion 2021-05-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05347459

    Cognitive Protective Effect of Newer Antidiabetic Drugs

    Alexandria University 100 participants Est. completion 2023-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05349474

    Metformin Treatment in Progressive Multiple Sclerosis

    Not yet reported University of California, Los Angeles 23 participants Est. completion 2025-05-30 1 site Stand-alone
    Other conditions: Secondary Progressive Multiple Sclerosis, Primary Progressive Multiple Sclerosis
    View official trial listing →
  • Completed NCT NCT05351021

    Efficacy of Metformin as Preventive Treatment in Paclitaxel Induced Peripheral Neuropathy in Breast Cancer Patients

    Not yet reported Mansoura University 76 participants Est. completion 2022-10-30 1 site Stand-alone
    Other conditions: Peripheral Neuropathy, Breast Cancer
    View official trial listing →
  • Completed NCT NCT05353686

    A Trial Investigating the Effect of 4 Weeks Dosing of XEN-D0501 on Blood Glucose Reduction in Patients With Diabetes

    Not yet reported Pila Pharma 54 participants Est. completion 2019-12-19 10 sites
    Type 2 diabetes Other conditions: Efficacy, Safety, Pharmacokinetics
    View official trial listing →
  • Completed NCT NCT05360147

    Liraglutide Improve Cognitive Function in Patients With Type 2 Diabetes Mellitus

    Not yet reported Third Military Medical University 30 participants Est. completion 2021-05-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05360537

    Effects of Degludec/Liraglutide on Time in Range, Inflammation and Endothelial Function vs Insulin Basal Bolus in Diabetic Inpatients

    Not yet reported University of Palermo 100 participants Est. completion 2022-04-20 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05362799

    Different Induction Protocols in PCOS After Clomiphene Citrate Failed Pregnancy in Non-IVF Cycles

    Not yet reported Menoufia University 176 participants Est. completion 2023-12-31
    Other conditions: Infertility, Female
    View official trial listing →
  • Completed NCT NCT05363384

    A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 25 mg and MET XR 1,000 mg) in Healthy Volunteers

    Not yet reported Celltrion 48 participants Est. completion 2022-07-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05363592

    A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 12.5 mg and MET XR 500 mg) in Healthy Volunteers

    Not yet reported Celltrion 48 participants Est. completion 2022-07-25 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05364164

    A Food Effect Study of CT-L01 After Oral Administration in Healthy Volunteers

    Not yet reported Celltrion 24 participants Est. completion 2022-07-25 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05365451

    Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters

    Not yet reported Washington State University 16 participants Est. completion 2023-07-22 1 site Stand-alone
    Other conditions: Interaction, Endogenous Biomarkers
    View official trial listing →
  • Active, not recruiting NCT NCT05366868

    Durable Effect of Imeglimin on the Glycemic Control in Patients With Type 2 Diabetes Mellitus

    Not yet reported National Center for Global Health and Medicine, Japan 567 participants Est. completion 2027-03-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05367063

    Canagliflozin and Myocardial Fibrosis

    Not yet reported Shanghai Zhongshan Hospital 45 participants Est. completion 2025-03-20 1 site
    Type 2 diabetes Other conditions: Cardiovascular Risk
    View official trial listing →
  • Completed NCT NCT05369793

    Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic Neuropathy

    Not yet reported Tanta University 60 participants Est. completion 2023-10-10 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabetic Neuropathies
    View official trial listing →
  • Completed NCT NCT05373680

    Efficacy and Safety of Metformin Versus Empagliflozin on Chronic Kidney Disease Progression

    Not yet reported, Not yet reported Tanta University 118 participants Est. completion 2024-04-01 2 sites Stand-alone
    Other conditions: Renal Insufficiency, Chronic
    View official trial listing →
  • Completed NCT NCT05376969

    Evaluate the Long Term Safety and Efficacy of DWP16001 add-on to Metformin in Patients With T2DM Inadequately Controlled on Metformin

    Not yet reported Daewoong Pharmaceutical Co. LTD. 159 participants Est. completion 2022-05-16 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05386186

    The Effect of Glimepiride Compared With Sitagliptin as an add-on Therapy to Metformin in Severe Insulin Deficiency Diabetes

    Not yet reported Peking University People's Hospital 192 participants Est. completion 2024-03-31 1 site Stand-alone
    Type 2 diabetes Other conditions: Severe Insulin Deficient Diabetes
    View official trial listing →
  • Completed NCT NCT05386706

    Treating PCOS With Digital Intervention vs. Metformin

    Not yet reported Shanghai 10th People's Hospital 80 participants Est. completion 2023-09-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT05395377

    Preventing Diabetes

    Not yet reported Geisinger Clinic 84 participants Est. completion 2021-11-16 1 site
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT05396378

    Early Recovery After Cesarean Delivery - Maternal Glucose Homeostasis Following Preoperative Glucose Dose

    Women's Hospital HUS 150 participants Est. completion 2023-12-31 1 site
    Other conditions: Gestational Diabetes, Cesarean Section Complications
    View official trial listing →
  • Completed NCT NCT05400863

    Effect of NNS on Metformin/GDF15, Pilot

    Not yet reported University of Florida 46 participants Est. completion 2024-08-02 1 site Stand-alone
    Other conditions: Obesity, Adolescent, Pre Diabetes
    View official trial listing →
  • Status unknown NCT NCT05412056

    Metformin to Prevent Preterm Birth in Twin Pregnancy

    Not yet reported, Not yet reported The University of Hong Kong 790 participants Est. completion 2025-06
    Other conditions: Preterm Birth, Premature Obstetric Labor, Twin; Complicating Pregnancy, Pregnancy Complications, Pregnancy Preterm, Metformin, Drug Effect
    View official trial listing →
  • Completed NCT NCT05413369

    iGlarLixi vs IDegAsp in Chinese Participants After OAD(s)

    Not yet reported Sanofi 582 participants Est. completion 2023-10-20 60 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05415644

    Study of the Bioequivalence and Food Effects of HRX0701 Tablets in Healthy Subjects

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 78 participants Est. completion 2022-08-08 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05416580

    Efficacy of Ursodeoxycholic Acid (UDCA) in Patients With Type 2 Diabetes

    Not yet reported University of Banja Luka 60 participants Est. completion 2024-04 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05418452

    Efficacy of 1% Metformin Gel Mixed With PRF in Augmenting Narrow Ridge

    Not yet reported Al-Azhar University 2 participants Est. completion 2023-06-15 1 site Stand-alone
    Other conditions: Horizontal Ridge Deficiency
    View official trial listing →
  • Status unknown NCT NCT05422092

    Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease

    Not yet reported First Affiliated Hospital Xi'an Jiaotong University 80 participants Est. completion 2023-12 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05429554

    The Effect of Metformin and DPP4 Inhibitors on Cognition and Cardiovascular Protection in Type 2 Diabetic Patients

    MTI University 60 participants Est. completion 2022-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05440591

    Effects of Dapagliflozin and Metformin on Vascular Function in Newly-Diagnosed Treatment-Naive Type 2 Diabetes

    Not yet reported Tan Tock Seng Hospital 150 participants Est. completion 2023-05-10 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT05451147

    A Comparative Study of the Effect of Ayurvedic Drugs and Metformin in the Management of Diabetes Mellitus (Type II)

    Not yet reported A & U Tibbia College Karol Bagh 48 participants Est. completion 2019-04-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05463094

    GXR RM China BE Study (Darmstadt - Jiangsu)

    Not yet reported Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 84 participants Est. completion 2023-01-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT05463627

    Effects of Metformin on Metabolic and Reproductive Outcomes in Chinese PCOS Patients

    RenJi Hospital 1440 participants Est. completion 2023-01-01 1 site
    Other conditions: Polycystic Ovary Syndrome, Metformin
    View official trial listing →
  • Status unknown NCT NCT05468554

    Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid Cancer

    Not yet reported Medical University of Bialystok 160 participants Est. completion 2026-04-30 1 site Stand-alone
    Other conditions: Thyroid Cancer
    View official trial listing →
  • Completed NCT NCT05478252

    A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 388 participants Est. completion 2023-09-18 104 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05479214

    Effect of Adding Metformin to Insulin in Uncontrolled Diabetic Patients During the 3rd Trimester of Pregnancy

    Not yet reported Cairo University 150 participants Est. completion 2023-02-10 1 site Stand-alone
    Other conditions: Diabetes Mellitus Pregnancy
    View official trial listing →
  • Completed NCT NCT05480007

    Non-alcoholic Fatty Liver Disease and Its Treatment

    Not yet reported Shanghai 10th People's Hospital 68 participants Est. completion 2018-12-01 Stand-alone
    MASLD
    View official trial listing →
  • Completed NCT NCT05504226

    Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin 25 mg and Metformin

    Not yet reported Handok Inc. 214 participants Est. completion 2024-06-18 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05504239

    Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin and Metformin

    Not yet reported Handok Inc. 235 participants Est. completion 2024-04-23 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05505994

    The Efficacy and Safety of DWP16001 in Combination With Metformin in T2DM Patients Inadequately Controlled on Metformin

    Not yet reported Daewoong Pharmaceutical Co. LTD. 340 participants Est. completion 2024-09 1 site
    Type 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease, Endocrine System Diseases
    View official trial listing →
  • Status unknown NCT NCT05507398

    The Anti-tumor Effect of Metformin And Atorvastatin in Breast Cancer

    Not yet reported Tanta University 100 participants Est. completion 2023-09
    Other conditions: Breast Cancer Female
    View official trial listing →
  • Status unknown NCT NCT05513729

    Effect of Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease

    First Affiliated Hospital Xi'an Jiaotong University 80 participants Est. completion 2024-03-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05519813

    Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.

    Not yet reported Bing He 60 participants Est. completion 2023-03-20 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT05521633

    Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty Liver

    Not yet reported King Edward Medical University 96 participants Est. completion 2022-05-24 1 site
    MASLD
    View official trial listing →
  • Completed NCT NCT05526690

    Study to Evaluate the Effect of CIN-107 on the Pharmacokinetics of the MATE Substrate, Metformin, in Healthy Subjects

    Not yet reported AstraZeneca 27 participants Est. completion 2020-12-12 1 site Stand-alone
    Other conditions: Hypertension
    View official trial listing →
  • Terminated NCT NCT05536037

    Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions

    Not yet reported Thomas Jefferson University 4 participants Est. completion 2024-03-16 1 site Stand-alone
    Other conditions: Erythroplakia, Leukoplakia, Oral Cavity Carcinoma, Proliferative Verrucous Leukoplakia
    View official trial listing →
  • Status unknown NCT NCT05536193

    Topical Metformin Emulgel VS Salicylic Acid Peeling in Treatment of Acne Vulgaris

    Not yet reported Assiut University 34 participants Est. completion 2023-09-10 Stand-alone
    Other conditions: Acne Vulgaris
    View official trial listing →
  • Completed NCT NCT05542420

    A Research Study, Looking at the Characterization of Treatment Intensified (Add on to Metformin) Real-world Adult Population With Type 2 Diabetes Mellitus in India, Pakistan and Thailand.

    Novo Nordisk A/S 3000 participants Est. completion 2023-04-20 3 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05545800

    Efficacy and Safety Of Different Regimens In Patients With Type 2 Diabetes Receiving Intensive Insulin Therapy

    Not yet reported Xiangya Hospital of Central South University 78 participants Est. completion 2024-06-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05549570

    Comparative Bioavailability Study of Metformin/Sitagliptin 850 mg/50 mg Tablets in Healthy Male and Female Volunteers

    Not yet reported Galenicum Health 26 participants Est. completion 2017-11-01 1 site Stand-alone
    Type 2 diabetes Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT05549583

    Comparative Bioavailability Study of Sitagliptin/Metformin 50 mg/1000 mg Tablets in Healthy Male and Female Volunteers

    Not yet reported Galenicum Health 26 participants Est. completion 2018-04-25 1 site Stand-alone
    Type 2 diabetes Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT05550129

    Study to Evaluate the Drug-drug Interactions Between Metformin and AMG 510 in Healthy Participants

    Not yet reported Amgen 13 participants Est. completion 2019-11-25 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Terminated NCT NCT05554679

    Maternal and Fetal Outcome With Metformin Therapy for Obese Pregnant Women .

    Not yet reported Assiut University 178 participants Est. completion 2023-07-11 1 site
    Other conditions: Metformin for Obese Pregnant Women
    View official trial listing →
  • Completed NCT NCT05571319

    A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome.

    Not yet reported University of Stellenbosch 30 participants Est. completion 2025-03-28 1 site Stand-alone
    Metabolic syndrome Other conditions: HIV Seropositivity
    View official trial listing →
  • Status unknown NCT NCT05572060

    Effect of Metformin Use on Mortality in Diabetic and Non Diabetic Patients With Sepsis and Septic Shock.

    Not yet reported Assiut University 75 participants Est. completion 2025-01-31
    Other conditions: Septic Shock
    View official trial listing →
  • Completed NCT NCT05572749

    Clinical Trial of Crocus Kozanis Administration in Obese Children and Adolescents

    Not yet reported Aristotle University Of Thessaloniki 75 participants Est. completion 2023-09-30 1 site Stand-alone
    Prediabetes Other conditions: Obesity, Dyslipidemias
    View official trial listing →
  • Withdrawn NCT NCT05580250

    A Study of LY3526318 in Healthy Male Japanese Participants

    Not yet reported Eli Lilly and Company Est. completion 2022-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT05580523

    Aspirin Versus Metformin in Pregnancies at High Risk of Preterm Preeclampsia: a 3-arm Randomized Controlled Trial

    Not yet reported Chinese University of Hong Kong 3000 participants Est. completion 2025-11-30 6 sites Stand-alone
    Other conditions: Preeclampsia
    View official trial listing →
  • Terminated NCT NCT05590676

    Metformin Treatment in Infants After Perinatal Brain Injury

    Not yet reported The Hospital for Sick Children 1 participants Est. completion 2024-02-22 1 site Stand-alone
    Other conditions: Hypoxic Ischemic Encephalopathy of Newborn, Premature Birth
    View official trial listing →
  • Status unknown NCT NCT05591235

    Effect of Metformin, Dapagliflozin, Combination of Metformin and Pioglitazone in Patients With Type 2 Diabetes

    Not yet reported Nanjing First Hospital, Nanjing Medical University 60 participants Est. completion 2023-02
    Other conditions: Type2diabetes, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT05601336

    of Sodium Glucose Cotransporter-2 Inhibitors on Metabolic, Hormonal and Clinical Parameters in PCO

    Not yet reported Beni-Suef University 200 participants Est. completion 2023-07-30 1 site
    Other conditions: PCO
    View official trial listing →
  • Completed NCT NCT05606913

    A Study of IBI362 in Participants With Type 2 Diabetes

    Not yet reported Innovent Biologics (Suzhou) Co. Ltd. 731 participants Est. completion 2024-04-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT05607316

    Evaluating the Efficacy and Safety of Metformin in Vitiligo

    Not yet reported University of Massachusetts, Worcester Est. completion 2028-11-01 1 site Stand-alone
    Other conditions: Vitiligo
    View official trial listing →
  • Completed NCT NCT05615012

    A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants

    Not yet reported Bristol-Myers Squibb 76 participants Est. completion 2023-12-13 1 site Stand-alone
    Other conditions: Healthy Participants
    View official trial listing →
  • Completed NCT NCT05615467

    A Study of Effect of LY3556050 on Metformin in Healthy Participants

    Not yet reported Eli Lilly and Company 18 participants Est. completion 2022-12-27 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05628584

    High FODMAP Diet With Metformin in preDM

    Not yet reported Elaine Chow 26 participants Est. completion 2023-10-15 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT05629806

    Effect of Acarbose and Mixture of Pioglitazone and Metformin in Patients With Type 2 Diabetes

    Not yet reported Nanjing First Hospital, Nanjing Medical University 50 participants Est. completion 2023-05-31 1 site
    Type 2 diabetes Other conditions: Blood Glucose Fluctuation
    View official trial listing →
  • Completed NCT NCT05638893

    Metformin as Adjuvant Therapy in Obese Knee Osteoarthritis Patients

    Not yet reported, Not yet reported Tanta University 50 participants Est. completion 2022-04-15 1 site Stand-alone
    Osteoarthritis
    View official trial listing →
  • Status unknown NCT NCT05641337

    Research on Optimal Strategy of Hypoglycemic Therapy for Cirrhosis With Diabetes

    Not yet reported Huashan Hospital 184 participants Est. completion 2025-12-30 1 site Stand-alone
    Other conditions: Liver Cirrhosis, Diabetes
    View official trial listing →
  • Status unknown NCT NCT05646199

    Semaglutide vs Metformin in Polycystic Ovary Syndrome (PCOS)

    Not yet reported, Not yet reported University of Hull 60 participants Est. completion 2025-12-30 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT05653895

    Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS

    Not yet reported Khyber Medical University Peshawar 120 participants Est. completion 2024-02-07 1 site
    Other conditions: PCOS
    View official trial listing →
  • Status unknown NCT NCT05655728

    Treatment With Metformin in Chinese Children With Alport Syndrome

    Not yet reported Peking University First Hospital 78 participants Est. completion 2025-04-20
    Other conditions: Alport Syndrome, Metformin
    View official trial listing →
  • Completed NCT NCT05657613

    Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects

    Not yet reported CTI BioPharma 60 participants Est. completion 2023-06-08 1 site Stand-alone
    Other conditions: Drug Interactions
    View official trial listing →
  • Status unknown NCT NCT05663736

    Effect of Gemigliptin Versus Glimepiride on Cardiac Diastolic Function in Patients With Type 2 Diabetes

    Not yet reported Seoul National University Bundang Hospital 80 participants Est. completion 2023-12-31 1 site
    Other conditions: Ejection Fraction
    View official trial listing →
  • Completed NCT NCT05680129

    A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Dulaglutide in Participants With T2DM

    Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 623 participants Est. completion 2024-10-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05680662

    The Study of Quadruple Therapy Quercetin, Zinc, Metformin, and EGCG as Adjuvant Therapy for Early, Metastatic Breast Cancer and Triple-negative Breast Cancer, a Novel Mechanism

    Not yet reported Ministry of Health, Saudi Arabia 200 participants Est. completion 2024-01-31 Stand-alone
    Other conditions: Breast Cancer Female, Triple Negative Breast Cancer
    View official trial listing →
  • Active, not recruiting NCT NCT05680805

    Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS

    Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 100 participants Est. completion 2025-11-30 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Metformin
    View official trial listing →
  • Completed NCT NCT05682495

    A HR20031 BE Study on Healthy Subjects

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 96 participants Est. completion 2023-04-04 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05688332

    Glycaemic & Cardiovascular Treatment Outcomes of Voglibose Vs Glibenclamide Added to Metformin in T2DM Patients

    Not yet reported University of Zambia 118 participants Est. completion 2024-01 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05694221

    Drug Drug Interaction (DDI) Between Supaglutide and Digoxin or Metformin

    Not yet reported Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. 34 participants Est. completion 2023-08-17 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT05702905

    Semaglutide Improves Metabolic Abnormalities and Fertility in Obese Infertile Women With Polycystic Ovary Syndrome

    Not yet reported Peking University First Hospital 75 participants Est. completion 2025-06-30 1 site Added to GLP-1
    Other conditions: PCOS (Polycystic Ovary Syndrome), Semaglutide
    View official trial listing →
  • Status unknown NCT NCT05703984

    A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fasting Conditions

    Not yet reported GC Biopharma Corp 50 participants Est. completion 2023-04-19 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT05708053

    Cardio-protective Effect of Metformin in Patients Undergoing PCI

    Not yet reported Future University in Egypt 80 participants Est. completion 2024-12 3 sites Stand-alone
    Other conditions: Elective Percutaneous Coronary Intervention, Ischemic Reperfusion Injury
    View official trial listing →
  • Completed NCT NCT05722951

    Metformin Efficacy and Safety in Epileptic Patients

    Not yet reported Tanta University 60 participants Est. completion 2024-06-20 1 site Stand-alone
    Other conditions: Epilepsy
    View official trial listing →
  • Status unknown NCT NCT05729386

    A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fed Conditions

    Not yet reported GC Biopharma Corp 34 participants Est. completion 2023-04-17 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT05740345

    New Approaches to INOCA

    Pasquale Mone 3000 participants Est. completion 2021-01-15
    Other conditions: New Approaches in INOCA
    View official trial listing →
  • Completed NCT NCT05741372

    A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver Cirrhosis

    Not yet reported Boehringer Ingelheim 28 participants Est. completion 2024-12-30 1 site Stand-alone
    Other conditions: Liver Cirrhosis
    View official trial listing →
  • Active, not recruiting NCT NCT05743387

    Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural Lesotho

    Not yet reported University Hospital, Basel, Switzerland 252 participants Est. completion 2027-12-31 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05743907

    Clinical Trial to Evaluate the Efficacy and Safety of DA-2811 When Added to Ongoing Metformin Monotherapy in Patients with Type 2 Diabetes Who Have Inadequate Glycemic Control

    Not yet reported Dong-A ST Co., Ltd. 231 participants Est. completion 2025-03-10 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT05753371

    Bioequivalence Study of Metformin Hydrochloride 500 mg Film-Coated Tablets in Indonesia Healthy Subject

    Not yet reported PT. Pyridam Farma Tbk 24 participants Est. completion 2022-03-31 1 site Stand-alone
    Other conditions: Drug Use
    View official trial listing →
  • Completed NCT NCT05759442

    Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics

    Not yet reported Bahria University 46 participants Est. completion 2023-07-15 1 site
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT05759897

    A 16 Week Study of HRS-7535 in Adults With Type 2 Diabetes Mellitus

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 180 participants Est. completion 2024-01-04
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05760456

    Safety and Efficacy of DIDALA Monotherapy in Patients With Type 2 Diabetes Compared With Metformin.

    Not yet reported Centre of Clinical Pharmacology, Hanoi Medical University 140 participants Est. completion 2024-08-31 2 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05760677

    Study on the Efficacy and Safety of Chiglitazar Sodium in PCOS With T2DM

    Not yet reported Affiliated Hospital of Nantong University 142 participants Est. completion 2024-09-30 1 site Stand-alone
    Type 2 diabetes Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
    View official trial listing →
  • Completed NCT NCT05762471

    Phase 1b/2a Study of GSBR-1290 in Adult Overweight or Obese Healthy Subjects and Subjects With Type 2 Diabetes Mellitus

    Not yet reported, Not yet reported Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics 142 participants Est. completion 2024-04-11 4 sites
    Type 2 diabetes Other conditions: Overweight or Obesity
    View official trial listing →
  • Status unknown NCT NCT05766540

    Add-on Aripiprazole on Cardiometabolic Profile in Treatment Resistant Schizophrenia: RCT

    Not yet reported All India Institute of Medical Sciences, Bhubaneswar 60 participants Est. completion 2023-12-31 Stand-alone
    Other conditions: Difference in the Change in Cardiovascular Risk in Treatment Resistant Schizophrenia
    View official trial listing →
  • Completed NCT NCT05767515

    The Effects of Acetyl-L-Carnitine and Myo/Chiro-Inositol in Patients With PCOS

    Not yet reported Khyber Medical University Peshawar 120 participants Est. completion 2024-03-10 1 site Stand-alone
    Other conditions: Infertility, Female, PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
    View official trial listing →
  • Completed NCT NCT05768360

    A Study to Assess the Effects of Savolitinib on the Pharmacokinetics of Digoxin, Rosuvastatin, Metformin, and Furosemide in Healthy Male Subjects

    Not yet reported AstraZeneca 6 participants Est. completion 2023-06-24 1 site Stand-alone
    Other conditions: Healthy Male Subjects
    View official trial listing →
  • Status unknown NCT NCT05779644

    Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes Mellitus

    Not yet reported RenJi Hospital 300 participants Est. completion 2025-02-23 1 site Stand-alone
    Type 2 diabetes Other conditions: Metformin, Obesity, Abdominal, Abdominal Fat, Non-Alcoholic Fatty Liver Disease, Metabolism Disorder, Glucose, Metabolism Disorder, Lipid
    View official trial listing →
  • Completed NCT NCT05781711

    Clinical Study to Evaluate the Possible Efficacy of Metformin in Patients With Parkinson's Disease

    Not yet reported Tanta University 60 participants Est. completion 2025-01-20 1 site
    Other conditions: Parkinson Disease
    View official trial listing →
  • Completed NCT NCT05790577

    Comparison of 30% Metformin and 2% Nicotinamide Lotion With Kligman Formula in the Treatment of Melasma

    Not yet reported Ishtiaq Ahmed 88 participants Est. completion 2023-02-15 1 site
    Other conditions: Melasma
    View official trial listing →
  • Completed NCT NCT05798715

    Bioequivalence Study of of Metformin HCl From Gleptomet 50/1000 mg F.C.Tablets (EVA Pharma, Egypt) and Janumet 50/1000 mg F.C.Tablets (Merck Sharp & Dohme, The Netherlands)

    Not yet reported Genuine Research Center, Egypt 30 participants Est. completion 2023-01-13 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT05801627

    SAL067 Treatment in Patients With Type 2 Diabetes Who Are Not Controlled by Metformin

    Not yet reported Shenzhen Salubris Pharmaceuticals Co., Ltd. 408 participants Est. completion 2022-05-24 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05802212

    Effect of Metformin on Patients With Polycystic Ovary Syndrome

    Not yet reported Peking University Third Hospital 77 participants Est. completion 2023-05-01 1 site Stand-alone
    Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
    View official trial listing →
  • Completed NCT NCT05815680

    A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese Subjects

    Not yet reported Innovent Biologics (Suzhou) Co. Ltd. 48 participants Est. completion 2023-10-30 1 site Stand-alone
    Other conditions: Overweight Subjects, Obese Subjects
    View official trial listing →
  • Completed NCT NCT05816057

    A Study of the Efficacy and Safety of Semaglutide Injection in the Treatment of Type 2 Diabetes Mellitus

    Not yet reported Hangzhou Jiuyuan Gene Engineering Co. Ltd., 476 participants Est. completion 2023-10-31 35 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05821543

    Efficacy and Safety of Sibutramin-containing Drugs in Patient With Alimentary Obesity

    Not yet reported Promomed, LLC 240 participants Est. completion 2021-05-21 8 sites Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT05822674

    Variable Effects of Anti-diabetics on Stress Hyperglycemia Ratio

    University of Diyala 80 participants Est. completion 2023-02-01 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05823870

    This Study is to Compare and Evaluate the Safety and Pharmacokinetic Characteristics (PK) After Administration of DW6014 and Each Component(Empagliflozin and Metformin) in Healthy Adult Volunteers in Fast Condition.

    Not yet reported Dong Wha Pharmaceutical Co. Ltd. 32 participants Est. completion 2023-03-20 1 site Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Status unknown NCT NCT05823883

    This Study is to Compare and Evaluate the Safety and Pharmacokinetic Characteristics (PK) After Administration of DW6014 and Each Component in Healthy Adult Volunteers in Fed Condition.

    Not yet reported Dong Wha Pharmaceutical Co. Ltd. 30 participants Est. completion 2023-08 1 site Stand-alone
    Other conditions: DW6014
    View official trial listing →
  • Withdrawn NCT NCT05828303

    A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors

    Not yet reported Turning Point Therapeutics, Inc. Est. completion 2025-11-30 33 sites Stand-alone
    Other conditions: Advanced Solid Tumor, Metastatic Solid Tumor
    View official trial listing →
  • Withdrawn NCT NCT05833958

    Polypill Versus Metformin in New Onset Type 2 Diabetes

    Not yet reported George Medicines PTY Limited Est. completion 2025-09 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05838573

    Metformin Treatment on Cognitive Impairment of Schizophrenia

    Not yet reported Central South University 120 participants Est. completion 2026-06-08 4 sites
    Other conditions: Schizophrenia
    View official trial listing →
  • Completed NCT NCT05840068

    IGF Level in Breast Cancer Patients Treated With Metformin

    Not yet reported Beni-Suef University 107 participants Est. completion 2021-07-31 1 site Stand-alone
    Other conditions: Breast Cancer Female
    View official trial listing →
  • Status unknown NCT NCT05847244

    The Effect of Addition of Metformin In Obese Non- Diabetic Patients With Heart Failure With Preserved Ejection Fraction

    Not yet reported Sara ElAdawy 80 participants Est. completion 2024-12-01 2 sites Stand-alone
    Other conditions: Diastolic Dysfunction, Obesity
    View official trial listing →
  • Status unknown NCT NCT05852639

    Fetal CPR at Term for Prediction of Adverse Neonatal Outcome in Pregnancies Complicated by GDM

    Cairo University 260 participants Est. completion 2024-04 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Withdrawn NCT NCT05854966

    CPI-613 Given With Metformin in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)

    Not yet reported Wake Forest University Health Sciences Est. completion 2025-09 Stand-alone
    Other conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory, Granulocytic Sarcoma
    View official trial listing →
  • Completed NCT NCT05874167

    A Pharmacokinetic Study of DW6013 (FDC of Linagliptin and Metformin) in Healthy Adult Volunteers

    Not yet reported Dong Wha Pharmaceutical Co. Ltd. 50 participants Est. completion 2022-10-11 1 site Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT05874180

    A Pharmacokinetic Study of DW6013 (FDC of Linagliptin and Metformin) in Healthy Adult Volunteers in Fed Condition

    Not yet reported Dong Wha Pharmaceutical Co. Ltd. 31 participants Est. completion 2023-02-03 1 site Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Status unknown NCT NCT05878535

    METFORMIN FOR ATRIAL FIBRILLATION

    Not yet reported Arab Contractors Medical Centre 770 participants Est. completion 2025-04 1 site
    Other conditions: Atrial Fibrillation
    View official trial listing →
  • Active, not recruiting NCT NCT05893225

    Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration

    Not yet reported University Hospital, Antwerp 120 participants Est. completion 2027-02-28 5 sites
    Other conditions: Multiple Sclerosis, Primary Progressive Multiple Sclerosis, Secondary-progressive Multiple Sclerosis
    View official trial listing →
  • Status unknown NCT NCT05893849

    Pharmacokinetics of Clinical Probes and Characteristics of Endogenous Biomarker in Chinese Older Adults

    Peking University Third Hospital 624 participants Est. completion 2024-04 1 site
    Other conditions: Aging
    View official trial listing →
  • Completed NCT NCT05900284

    Safety and Feasibility of Metformin for Sepsis Induced AKI

    Not yet reported Hernando Gomez 80 participants Est. completion 2026-05-18 1 site Stand-alone
    Other conditions: Sepsis, Septic Shock, Acute Kidney Injury, Metformin
    View official trial listing →
  • Status unknown NCT NCT05902468

    Ursodeoxycholic Acid as add-on Therapy in Type 2 Diabetes Mellitus

    Not yet reported, Not yet reported Tanta University 88 participants Est. completion 2024-11-28 2 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05906563

    Evaluation of Melatonin and Metformin Loaded Nanoparticles in the Treatment of Periodontal Intra-bony Defects

    Not yet reported Amira ragab 52 participants Est. completion 2024-06 1 site
    Other conditions: Bone Loss in Jaw
    View official trial listing →
  • Withdrawn NCT NCT05910554

    Investigation of the Efficacy of Metformin Therapy on Pulmonary Sarcoidosis

    Not yet reported University of Maryland, Baltimore Est. completion 2027-09-01
    Other conditions: Sarcoidosis, Pulmonary
    View official trial listing →
  • Completed NCT NCT05918068

    Pyridoxine Effect on the Blood Glucose Level in Type 2 Diabetic Patients

    Not yet reported Al-Rasheed University College 108 participants Est. completion 2023-04-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05921942

    The Impact of Metformin Administration on the Clinical Outcome of Stage IV Colon Cancer

    Not yet reported Ain Shams University 70 participants Est. completion 2022-12-30 1 site
    Other conditions: Colorectal Cancer
    View official trial listing →
  • Suspended NCT NCT05932251

    Towards Precision Medicine for Diabetes in Pregnancy

    Zuyderland Medisch Centrum 103 participants Est. completion 2025-09-30 1 site
    Other conditions: Gestational Diabetes, Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT05939921

    Effects of Metformin Therapy on Pancreatic and Hepatic Fat Content in Patients of Type 2 Diabetes Mellitus

    Not yet reported Diabetes Foundation, India 15 participants Est. completion 2023-06-30 1 site Stand-alone
    Other conditions: Type2diabetes
    View official trial listing →
  • Status unknown NCT NCT05942963

    Efficacy of Empagliflozin and Pioglitazone in Diabetic Patients With NAFLD

    Not yet reported Jinnah Postgraduate Medical Centre 240 participants Est. completion 2024-04 1 site Stand-alone
    Other conditions: Non-Alcoholic Fatty Liver Disease, Type2diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT05949008

    Effect of Metformin, a Drug Used to Treat Diabetes, vs Placebo

    Not yet reported University of California, Los Angeles 150 participants Est. completion 2028-07-30 1 site Stand-alone
    Other conditions: NIDDM, Obesity
    View official trial listing →
  • Status unknown NCT NCT05950516

    Efficacy and Safety of Semaglutide Ingection in Subjects With Type 2 Diabetes

    Not yet reported Qilu Pharmaceutical Co., Ltd. 478 participants Est. completion 2025-01-22 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT05952349

    Effect of Metformin and Combination of Olive Oil Plus Nutritional Supplements on Inflammatory Markers IL-6 and IL-8 in PCOS.

    Not yet reported Khyber Medical University Peshawar 88 participants Est. completion 2024-04-01 1 site
    Other conditions: PCO
    View official trial listing →
  • Not yet recruiting NCT NCT05957991

    Danish Precocious Puberty Study - DAPP Study A National Cohort Study on Incidence and Etiologies for Precocious Puberty

    Copenhagen University Hospital at Herlev 1500 participants Est. completion 2030-09 5 sites
    Other conditions: Puberty, Precocious
    View official trial listing →
  • Completed NCT NCT05965219

    A Trial to Evaluate the Effects of Itraconazole and Carbamazepine on the Pharmacokinetics of Emraclidine and of Emraclidine on the Pharmacokinetics of Metformin in Healthy Adult Participants

    Not yet reported Cerevel Therapeutics, LLC 60 participants Est. completion 2023-11-10 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT05965908

    Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome

    Not yet reported Beni-Suef University 183 participants Est. completion 2025-12-30 1 site
    Other conditions: Polycystic Ovary
    View official trial listing →
  • Completed NCT NCT05966792

    SGLT2 Inhibitors in Treating Patients With PCOS

    Not yet reported Shanghai 10th People's Hospital 82 participants Est. completion 2025-06-30 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT05977465

    Empagliflozin in Treatment of Peripheral Diabetic Neuropathy

    Not yet reported, Not yet reported Tanta University 50 participants Est. completion 2023-08-03 1 site Stand-alone
    Other conditions: Diabetic Neuropathy Peripheral
    View official trial listing →
  • Status unknown NCT NCT05979038

    Clinical Evaluation of the Effect of Metformin in Sepsis

    Not yet reported German University in Cairo 110 participants Est. completion 2024-07-10 1 site Stand-alone
    Other conditions: Sepsis
    View official trial listing →
  • Completed NCT NCT05981365

    Voxelotor CYP and Transporter Cocktail Interaction Study

    Not yet reported Pfizer 44 participants Est. completion 2023-10-04 1 site Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Completed NCT NCT05981742

    Effects of Combined Metformin and Cabergoline in Comparison With Metformin Only Therapy on Ovarian and Hormonal Activities in Iraqi Patients With PCOS

    Not yet reported Al-Rasheed University College 75 participants Est. completion 2023-03-31 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT05986838

    Effect of Laser Puncture Versus Ultraviolet Radiation on Women With Polycystic Ovarian Syndrome

    Not yet reported Cairo University 100 participants Est. completion 2024-04 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT05988684

    Effect of Metformin on Carotid Atherosclerosis for Non-diabetic Patients With PsA (CAMPA Study)

    Not yet reported Chinese University of Hong Kong 24 participants Est. completion 2025-09-30 1 site Stand-alone
    Other conditions: PsA (Psoriatic Arthritis)
    View official trial listing →
  • Completed NCT NCT05990205

    Effect of the SCL16A11 Risk Haplotype on Treatments to Prevent Type 2 Diabetes

    Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 437 participants Est. completion 2024-03-01 1 site
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT05994586

    The Efficacy of AP029 Mix in Patients With Impaired Carbohydrate Metabolism

    Not yet reported AronPharma Sp. z o. o. 30 participants Est. completion 2023-11-26 1 site Stand-alone
    Prediabetes Other conditions: Diabetes in Adolescence
    View official trial listing →
  • Completed NCT NCT05998837

    GLUcose Transport and REnalPROtection in Chronic Kidney Disease

    Not yet reported, Not yet reported IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy 34 participants Est. completion 2024-09-30 1 site
    Chronic kidney diseaseType 2 diabetes Other conditions: Hypertension
    View official trial listing →
  • Active, not recruiting NCT NCT06000462

    The Effect of Dapagliflozin on Weight Loss in Obese Adults Without Diabetes

    Not yet reported Oman Ministry of Health 150 participants Est. completion 2025-12-30 1 site
    Other conditions: Obesity, Dapagliflozin Adverse Reaction, Weight Loss, Effect of Drug
    View official trial listing →
  • Active, not recruiting NCT NCT06005142

    Therapeutic Intervention of Eriomin Associated with Metformin in the Control of Hyperglycemia in Pre-Diabetic Patients

    Not yet reported Thais Cesar 80 participants Est. completion 2024-12-30 1 site
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT06010992

    Nitazoxanide as Adjuvant Therapy in Type 2 Diabetes Mellitus

    Not yet reported Tanta University 70 participants Est. completion 2025-01-01 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06012682

    Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility

    Not yet reported Medical University of Bialystok 200 participants Est. completion 2027-09-30 Stand-alone
    Other conditions: Infertility, Female
    View official trial listing →
  • Completed NCT NCT06015594

    Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.

    Not yet reported University of Cagliari 168 participants Est. completion 2022-05-01 Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT06031168

    1% Metformin Gel-coated Implants and Osteointegration and Crestal Marginal Bone Loss

    Not yet reported Hams Hamed Abdelrahman 26 participants Est. completion 2023-11-30 1 site Stand-alone
    Other conditions: Osteointegration
    View official trial listing →
  • Status unknown NCT NCT06041399

    The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy

    Not yet reported First Affiliated Hospital of Wenzhou Medical University 1400 participants Est. completion 2025-01-02 1 site Stand-alone
    Other conditions: Diabetic Peripheral Neuropathy
    View official trial listing →
  • Completed NCT NCT06042855

    ACTIV-6: COVID-19 Study of Repurposed Medications - Arm G (Metformin)

    Not yet reported Susanna Naggie, MD 3214 participants Est. completion 2024-11-04 110 sites Stand-alone
    Other conditions: Covid19
    View official trial listing →
  • Completed NCT NCT06045221

    A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin

    Not yet reported Eli Lilly and Company 1698 participants Est. completion 2025-08-22 131 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06049186

    CRD vs. Met in Patients With Obese PCOS Infertility

    Not yet reported Shanghai First Maternity and Infant Hospital 406 participants Est. completion 2026-03-31 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT06057246

    Individual Determinants of Postprandial Glucose Response in Type 2 Diabetes

    Not yet reported Federico II University 144 participants Est. completion 2025-05 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06059287

    The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics

    Not yet reported RenJi Hospital 64 participants Est. completion 2025-12-31
    Type 2 diabetes Other conditions: Obesity, Sodium-glucose Co-transporter-2 Inhibitor, Myocardial Fibrosis, Magnetic Resonance Imaging
    View official trial listing →
  • Status unknown NCT NCT06064552

    Screening For First Trimester's Hyperglycemia in High and Low Risk Pregnancy

    Sohag University 100 participants Est. completion 2024-09-24 1 site
    Other conditions: Screening for Hyperglycemia in First Trimester in High and Low Risk Pregnancy
    View official trial listing →
  • Completed NCT NCT06065540

    A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor

    Not yet reported Novo Nordisk A/S 2734 participants Est. completion 2026-01-06 405 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06066060

    A DDI Study of JMKX000623 and Metformin Hydrochloride

    Not yet reported Jemincare 24 participants Est. completion 2023-11-06 1 site Stand-alone
    Other conditions: Healthy, Drug-Drug Interaction
    View official trial listing →
  • Completed NCT NCT06068686

    Vildagliptin Versus Glimepiride in Type 2 Diabetic Patients

    Not yet reported Damanhour University 70 participants Est. completion 2024-12-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06071442

    Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine

    Not yet reported Alexion Pharmaceuticals, Inc. 60 participants Est. completion 2024-04-12 1 site Stand-alone
    Other conditions: Healthy Participants
    View official trial listing →
  • Completed NCT NCT06073600

    Bioequivalence Study to Compare Metformin / Vildagliptin Versus Galvumet®

    Not yet reported Reseach Laboratory of Clinical and Experimental Pharmacology 18 participants Est. completion 2022-11-13 1 site Stand-alone
    Other conditions: Fed Conditions
    View official trial listing →
  • Status unknown NCT NCT06080802

    The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction

    Not yet reported, Not yet reported October University for Modern Sciences and Arts 80 participants Est. completion 2024-12-01 1 site Stand-alone
    Heart failure Other conditions: Diabete Type 2
    View official trial listing →
  • Withdrawn NCT NCT06083675

    Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S Est. completion 2027-05-28 100 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06083935

    Evaluation of the Effects of Diosmin/Hespiridin Combination on the Clinical Outcomes in Patients With Polycystic Ovary Syndrome

    Not yet reported Ain Shams University 120 participants Est. completion 2024-12-01
    Other conditions: Poly Cystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT06084156

    A Study to Evaluate the DDI of HSK7653 With Metformin

    Not yet reported Haisco Pharmaceutical Group Co., Ltd. 22 participants Est. completion 2019-12-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06085703

    Effects of Henagliflozin on the Brain Function in T2DM Patients With Mild Cognitive Impairment: a Randomized, Parallel Controlled Clinical Trial

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 24 participants Est. completion 2025-06-30 1 site Stand-alone
    Type 2 diabetes Other conditions: Mild Cognitive Impairment
    View official trial listing →
  • Status unknown NCT NCT06087796

    Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata.

    Not yet reported Assiut University 60 participants Est. completion 2024-10 1 site Stand-alone
    Other conditions: Alopecia Areata
    View official trial listing →
  • Completed NCT NCT06092060

    The Effect of a Multistrain Probiotic on Metformin Tolerance and Efficacy With Microbiota and Stool Metabolome in Insulin-resistant Women - a 12-week Randomized, Placebo-controlled, Double-blind Study

    Not yet reported Poznan University of Physical Education 40 participants Est. completion 2023-07-20 1 site
    Other conditions: Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT06096454

    Effect of Life Style Modification and Metformin on Hypothyroidism With Insulin Resistance

    Not yet reported Assiut University 100 participants Est. completion 2024-10-30 Stand-alone
    Other conditions: Hypothyroidism, Insulin Resistance
    View official trial listing →
  • Terminated NCT NCT06100822

    Managing Chronic Tendon Pain by Metformin

    Not yet reported James Wang 21 participants Est. completion 2026-08-24 1 site Stand-alone
    Other conditions: Tendinopathy, Chronic Pain, Achilles Tendinopathy
    View official trial listing →
  • Completed NCT NCT06101147

    Effect of Vitamin D Supplementation on Testosterone Level in Women With Polycystic Ovary Syndrome

    Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 66 participants Est. completion 2024-07-30 1 site Stand-alone
    Other conditions: PCOS, Vitamin D
    View official trial listing →
  • Completed NCT NCT06103747

    Bioequivalence Study to Compare Metformin / Vildagliptin (850 mg/50 mg) Versus Galvumet®

    Not yet reported Reseach Laboratory of Clinical and Experimental Pharmacology 18 participants Est. completion 2023-08-15 1 site Stand-alone
    Other conditions: Fed Conditions
    View official trial listing →
  • Completed NCT NCT06107153

    Effect of Short-term Basal Insulin Initiation in Newly Diagnosed Type 2 Diabetes on 1-year Glycemic Control

    Not yet reported University of Basrah 243 participants Est. completion 2024-11-01 1 site
    Other conditions: Type2diabetes
    View official trial listing →
  • Completed NCT NCT06109311

    A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor

    Not yet reported Eli Lilly and Company 546 participants Est. completion 2025-09-15 70 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06124495

    Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.

    Not yet reported Galenicum Health 58 participants Est. completion 2023-02-13 1 site Stand-alone
    Type 2 diabetes Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT06124547

    Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.

    Not yet reported Galenicum Health 48 participants Est. completion 2023-02-13 1 site Stand-alone
    Type 2 diabetes Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT06124560

    Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.

    Not yet reported Galenicum Health 58 participants Est. completion 2022-11-07 1 site Stand-alone
    Type 2 diabetes Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT06124573

    Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.

    Not yet reported Galenicum Health 48 participants Est. completion 2022-11-21 1 site Stand-alone
    Type 2 diabetes Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT06125587

    Chiglitazar/Metformin in Non-obese Women With PCOS

    Not yet reported, Not yet reported Shengjing Hospital 55 participants Est. completion 2024-11-20 1 site
    Other conditions: Polycystic Ovary Syndrome, Chiglitazar, Metformin
    View official trial listing →
  • Status unknown NCT NCT06126029

    Effect of Metformin as Add-on Therapy to Ibuprofen on Disease Activity in Knee Osteoarthritis Patients.

    Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 68 participants Est. completion 2024-06-30 1 site Stand-alone
    Osteoarthritis Other conditions: Metformin
    View official trial listing →
  • Status unknown NCT NCT06127433

    The Effect of Short-term Insulin Intensive Therapy Based on the Application of Insulin Pump and Real-time Dynamic Glucose Monitoring Technology on Reversing the Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 210 participants Est. completion 2024-12-30 1 site
    Other conditions: Insulin Pump,Continuous Glucose Monitoring Technology
    View official trial listing →
  • Completed NCT NCT06128967

    A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial

    Not yet reported Cardresearch 399 participants Est. completion 2025-08-01 6 sites
    Other conditions: Long COVID-19 Syndrome, Chronic Fatigue Syndrome
    View official trial listing →
  • Not yet recruiting NCT NCT06135584

    Study on MAFLD-related Cirrhosis Prevention and Treatment Strategies

    Not yet reported The Affiliated Hospital of Hangzhou Normal University 1000 participants Est. completion 2026-12-31 Stand-alone
    Other conditions: Metabolic Dysfunction-associated Fatty Liver Disease, Cirrhosis
    View official trial listing →
  • Status unknown NCT NCT06140485

    A Trial to Investigate the Efficacy and Safety of NW Low-Glu® in Patients With Type II Diabetes Mellitus

    Not yet reported Natural Wellness Egypt 400 participants Est. completion 2025-10
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06141980

    Study to Evaluate the Long Term Safety and Efficacy of DWP16001 in Patients With Type 2 Diabetes Mellitus

    Not yet reported Daewoong Pharmaceutical Co. LTD. 134 participants Est. completion 2025-09
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06145360

    Evaluating the Efficacy and Safety of Empagliflozin Addition to Insulin and Oral Antidiabetic Medication (OAD) Regimen in Poorly Controlled Type 2 Diabetes and Obese Patient

    Not yet reported SINA Health Education and Welfare Trust 150 participants Est. completion 2024-03-01 1 site Stand-alone
    Type 2 diabetes Other conditions: Glucose Metabolism Disorders, Hypoglycemic Agents, Empagliflozin
    View official trial listing →
  • Status unknown NCT NCT06147050

    Effect of Metformin in Reducing Fatigue in Long COVID in Adolescents

    Not yet reported Purpose Life Sciences 16 participants Est. completion 2024-12 1 site Stand-alone
    Other conditions: Long COVID
    View official trial listing →
  • Status unknown NCT NCT06147518

    To Compare the Safety and Efficacy of Dapagliflozin Plus Metformin Versus Sitagliptin Plus Metformin for Treatment of Diabetes in Patients With Compensated and Stable Decompensated Cirrhosis

    Not yet reported Institute of Liver and Biliary Sciences, India 240 participants Est. completion 2024-12-31 1 site Stand-alone
    Other conditions: Compensated Cirrhosis, Decompensated Cirrhosis
    View official trial listing →
  • Completed NCT NCT06160414

    A Study to Investigate the Potential Drug Interactions Between ALXN2080 and Rosuvastatin and Metformin in Healthy Adult Participants

    Not yet reported Alexion Pharmaceuticals, Inc. 20 participants Est. completion 2024-02-05 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT06161844

    Efficacy and Safety of Semaglutide Injection (HD1916) in Patients With Type 2 Diabetes Mellitus

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 506 participants Est. completion 2025-05-14 1 site Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06164535

    The Effects of DPPIs on Cognitive Function of Diabetic Patients

    Not yet reported Beni-Suef University 105 participants Est. completion 2024-07-15 1 site Stand-alone
    Other conditions: Cognitive Impairment
    View official trial listing →
  • Completed NCT NCT06170463

    Insulin Sensitizers Role in Control of PCOS Vicious Cycle.

    Not yet reported Zagazig University 210 participants Est. completion 2023-04-15 1 site
    Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
    View official trial listing →
  • Status unknown NCT NCT06181422

    Metformin and Lactoferrin in Sepsis in Icu

    Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2024-06-09 1 site
    Other conditions: Sepsis
    View official trial listing →
  • Status unknown NCT NCT06182618

    Retrospective Analysis for Patients With Metabolic Syndrome

    Second Affiliated Hospital, Zhejiang University, School of Medicine 400 participants Est. completion 2024-01-01 1 site
    Metabolic syndrome
    View official trial listing →
  • Status unknown NCT NCT06188234

    The Prescription Patterns and Clinical Efficacy of Tenero Tab/Tenero M SR Tab

    Hanlim Pharm. Co., Ltd. 3000 participants Est. completion 2026-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06192108

    A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin

    Not yet reported Eli Lilly and Company 962 participants Est. completion 2025-09-26 74 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06199544

    Effect of Unani Medicine for the Management of Anomalies Associated With Polycystic Ovarian Syndrome

    Not yet reported Hamdard University 150 participants Est. completion 2024-12-01 1 site
    Other conditions: Comparative Study
    View official trial listing →
  • Status unknown NCT NCT06203275

    The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus

    Not yet reported aya ramadan ashmawy sarhan 44 participants Est. completion 2026-01
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06204107

    A Clinical Trial to Evaluate the Food Effect on Pharmacokinetic Profiles and Safety of CKD-379

    Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2023-12-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06204185

    Clinical and Biochemical Evaluation of 1% Metformin in Non-surgical Treatment of Periodontitis

    Not yet reported Ain Shams University 40 participants Est. completion 2022-11-30 1 site
    Other conditions: Periodontitis
    View official trial listing →
  • Status unknown NCT NCT06215976

    The Nephroprotective Effect of Metformin With Cisplatin in Bladder Cancer

    Not yet reported Cairo University 78 participants Est. completion 2024-12-30 1 site
    Other conditions: Muscle-Invasive Bladder Carcinoma
    View official trial listing →
  • Status unknown NCT NCT06217887

    Efficacy Comparison of Polyethylene Glycol Loxenatide and Gliclazide on the Brain Function in T2DM Patients

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 58 participants Est. completion 2024-06 1 site Stand-alone
    Type 2 diabetes Other conditions: Cognitive Function Abnormal
    View official trial listing →
  • Status unknown NCT NCT06218342

    Henagliflozin in Relieving Type 2 Diabetes With Non-alcoholic Fatty Liver Disease

    Not yet reported Sir Run Run Shaw Hospital 156 participants Est. completion 2025-12-31 Stand-alone
    Type 2 diabetes Other conditions: Non-Alcoholic Fatty Liver Disease
    View official trial listing →
  • Completed NCT NCT06221969

    A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor

    Not yet reported Novo Nordisk A/S 1024 participants Est. completion 2026-04-06 197 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06227832

    A Study to Determine the Effect of KP-001 on Metformin and Midazolam Pharmacokinetics and the Effect of Clarithromycin on KP-001 Pharmacokinetics in Healthy Adult Participants

    Not yet reported Kaken Pharmaceutical 38 participants Est. completion 2024-07-31 1 site Stand-alone
    Other conditions: Healthy Adults
    View official trial listing →
  • Completed NCT NCT06229795

    Effect of Green Tea on Obese Pediatrics With Prediabetes

    Not yet reported Ain Shams University 90 participants Est. completion 2024-11-19 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Status unknown NCT NCT06233201

    Sitagliptin and Metformin Hydrochloride Tablets 50 mg/500 mg Relative to Originator

    Not yet reported Bio-innova Co., Ltd 34 participants Est. completion 2024-07-28 Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Status unknown NCT NCT06233240

    Sitagliptin and Metformin Hydrochloride Tablets 50 mg/1000 mg Relative to Originator

    Not yet reported Bio-innova Co., Ltd 34 participants Est. completion 2024-06-12 Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT06235086

    A Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes Mellitus

    Not yet reported CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. 632 participants Est. completion 2026-02-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06243536

    The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients

    Not yet reported University Hospital Sestre Milosrdnice 60 participants Est. completion 2024-12-31 1 site
    Type 2 diabetes Other conditions: Overweight, Disordered Eating Behaviors
    View official trial listing →
  • Status unknown NCT NCT06244407

    The Bioequivalence Study of Fixed-dose Combination of Vildagliptin and Metformin HCI 50/1000 mg FCT Under Fed Conditions

    Not yet reported International Bio service 40 participants Est. completion 2024-06-02 Stand-alone
    Other conditions: Healthy Volunteer
    View official trial listing →
  • Completed NCT NCT06244550

    Clinical Trials Using HepatoKeeper Herbal Essentials to Treat Non-alcoholic Fatty Liver Disease and Metabolic Factors

    Not yet reported Taipei City Hospital 60 participants Est. completion 2023-06-13 1 site Stand-alone
    Other conditions: Non-alcoholic Fatty Liver Disease, Liver Fibrosis, Liver Injury
    View official trial listing →
  • Completed NCT NCT06247748

    Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects

    Not yet reported Beijing Dongfang Biotech Co., Ltd. 28 participants Est. completion 2024-04-15 1 site
    Type 2 diabetes Other conditions: Overweight
    View official trial listing →
  • Status unknown NCT NCT06248801

    Vildagliptin and Metformin Tablets 50/1000 mg Relative to GALVUS MET (50mg/1000 mg) Tablets

    Not yet reported Bio-innova Co., Ltd 48 participants Est. completion 2024-10-15 Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Status unknown NCT NCT06252194

    Comparative Study of Metformin Versus Doxycycline in Moderate to Severe Adult Acne Vulgaris Patients.

    Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 120 participants Est. completion 2024-03 1 site Stand-alone
    Other conditions: Acne Vulgaris
    View official trial listing →
  • Status unknown NCT NCT06256289

    Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome

    Not yet reported Ping Li,MD 50 participants Est. completion 2025-04-30 Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease
    View official trial listing →
  • Active, not recruiting NCT NCT06257966

    A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Dulaglutide in Combination Therapy Diabetes Mellitus Type 2 Patients With Metformin

    Not yet reported Beijing Dongfang Biotech Co., Ltd. 600 participants Est. completion 2026-11-30 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT06260722

    Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)

    Not yet reported Eli Lilly and Company 1250 participants Est. completion 2027-02 77 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06266598

    Effectiveness of Antidiabetic Treatment Applied in Childhood Obesity

    Not yet reported HÜMEYRA ACIKAN 52 participants Est. completion 2021-10-27 1 site
    Other conditions: Childhood Obesity, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT06280274

    Metformin Use in Patients Undergoing Total Joint Replacement Surgery

    Not yet reported Oregon Health and Science University 40 participants Est. completion 2025-09-15 1 site Stand-alone
    Other conditions: Hyperglycemia
    View official trial listing →
  • Terminated NCT NCT06296836

    Effect of Continuing Versus Holding Metformin During Hospitalizations.

    Not yet reported University of Illinois at Chicago 22 participants Est. completion 2026-04-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT06297603

    Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

    Not yet reported Eli Lilly and Company 320 participants Est. completion 2026-11 76 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06323161

    A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without Metformin

    Not yet reported Novo Nordisk A/S 274 participants Est. completion 2025-10-23 61 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06325956

    PCOS Immune Function Predicts Metformin Efficacy

    Not yet reported Shanghai 10th People's Hospital 100 participants Est. completion 2026-07-01 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Metformin, Immune Function
    View official trial listing →
  • Completed NCT NCT06326840

    Clinical Efficacy and Adverse Reactions of Antipsychotic Treatment

    Not yet reported Taipei Medical University Hospital 42 participants Est. completion 2011-06-10 1 site Stand-alone
    Other conditions: Metabolic Disturbance, Hyperprolactinemia, Schizophrenia
    View official trial listing →
  • Completed NCT NCT06327191

    EMERGE Mothers and Kids

    National University of Ireland, Galway, Ireland 370 participants Est. completion 2026-04-02 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT06327815

    Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM

    Not yet reported AstraZeneca 633 participants Est. completion 2025-06-30 35 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06328426

    Vitamin D With Omega-3 or Metformin in Osteoarthritis

    Not yet reported Assiut University 60 participants Est. completion 2026-12
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT06332612

    Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial

    Not yet reported, Not yet reported Ziauddin University 30 participants Est. completion 2025-01-06 1 site Stand-alone
    Other conditions: Oral Submucous Fibrosis
    View official trial listing →
  • Terminated NCT NCT06333080

    The Effect of Adherence to Oral Semaglutide on Glycaemic Control in People With Type 2 Diabetes Treated With Metformin

    Aalborg University Hospital 1 participants Est. completion 2025-07-29 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06335134

    A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin

    Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 57 participants Est. completion 2024-06-28 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT06339086

    Efficacy and Safety of Semaglutide Injection in Subjects With Type 2 Diabetes

    Not yet reported Chengdu Brilliant Pharmaceutical Co., Ltd. 478 participants Est. completion 2025-12-30 Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06353061

    Chemoradiotherapy With or Without Metformin in Locally Advanced Cervical Cancer

    Not yet reported Peking Union Medical College Hospital 51 participants Est. completion 2026-02-01 1 site Stand-alone
    Other conditions: Cervical Cancer, Radiotherapy, Metformin, Hypoxia, PET/CT
    View official trial listing →
  • Completed NCT NCT06353347

    Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

    Not yet reported Shenzhen HighTide Biopharmaceutical Ltd. 551 participants Est. completion 2025-07-30 64 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06357273

    The Effect of White Tea Consumption on Obesity

    Recep Tayyip Erdogan University 91 participants Est. completion 2023-12-15 1 site
    Other conditions: Obesity, Obesity; Endocrine, Obesity Adult Onset
    View official trial listing →
  • Terminated NCT NCT06359015

    Metformin and Esomeprazole in Preterm Pre-eclampsia

    Not yet reported Christiana Care Health Services 4 participants Est. completion 2025-05-08 1 site Stand-alone
    Other conditions: Preeclampsia Severe, Pre-Eclampsia, Preeclampsia, Preeclampsia Second Trimester, Preeclampsia Complicating Childbirth, Preeclampsia Puerperium, Preterm
    View official trial listing →
  • Completed NCT NCT06370247

    First-time Usage of SGLT2 Inhibitors in Type 2 Diabetic Patients Who Are Fasting During Ramadan: Safety and Efficacy

    Not yet reported Sohag University 60 participants Est. completion 2023-09-25 1 site
    Type 2 diabetes Other conditions: SGLT2 Inhibitors, First Time Use, Fasting in Ramadan
    View official trial listing →
  • Completed NCT NCT06393348

    Efficacy and Safety of HRS-7535 Tablets in T2DM Subjects Poorly Controlled With Metformin and SGLT2i.

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 155 participants Est. completion 2025-03-13 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06405178

    Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome

    Not yet reported Beni-Suef University 200 participants Est. completion 2026-04-01 1 site Stand-alone
    Other conditions: Polycystic Ovary
    View official trial listing →
  • Status unknown NCT NCT06405971

    Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE)

    Not yet reported Ming Lv 60 participants Est. completion 2025-06-01 1 site Stand-alone
    Other conditions: Dissecting Aneurysm of Cerebral Artery
    View official trial listing →
  • Completed NCT NCT06415773

    Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

    Not yet reported Shenzhen HighTide Biopharmaceutical Ltd. 367 participants Est. completion 2025-07-25 53 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06416800

    A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants

    Not yet reported Incyte Corporation 71 participants Est. completion 2025-01-15 1 site Stand-alone
    Other conditions: Healthy Participants
    View official trial listing →
  • Not yet recruiting NCT NCT06417489

    Evaluation of Efficacy and Safety of Combination Therapy of Henagliflozin Proline, Retagliptin and Metformin in New Diagnosed Type 2 Diabetes Patients

    Not yet reported Peking University First Hospital 160 participants Est. completion 2026-12-31 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Enrolling by invitation NCT NCT06429007

    A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury

    Not yet reported Boston Children's Hospital 30 participants Est. completion 2029-03-01 1 site Stand-alone
    Other conditions: Hypoxic-Ischemic Encephalopathy, HIE, Neurodevelopment, Infant Development
    View official trial listing →
  • Status unknown NCT NCT06430125

    Nephroprotective Effect of Nicorandil in Type 2 Diabetes Mellitus

    Not yet reported Tanta University 46 participants Est. completion 2025-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06439758

    Effects of First-Line Oral Hypoglycemics in Bone Markers of Treatment Naïve Saudi Adults With Type 2 Diabetes

    Not yet reported King Saud University 111 participants Est. completion 2025-12-01 Stand-alone
    Other conditions: Diabetes Type 2, Osteoporosis
    View official trial listing →
  • Status unknown NCT NCT06449235

    Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh

    Not yet reported Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders 938 participants Est. completion 2025-06 1 site
    Other conditions: Type2diabetes
    View official trial listing →
  • Completed NCT NCT06450262

    Bioequivalence Study to Compare Empagliflozin/ Metformin HCl 12.5mg/1000mg Film-coated Tablets

    Not yet reported Humanis Saglık Anonim Sirketi 36 participants Est. completion 2024-03-05 1 site Stand-alone
    Other conditions: Type2diabetes
    View official trial listing →
  • Completed NCT NCT06452017

    Effects of Telerehabilitation Exercise Program on Maternal Glycemic Control

    Not yet reported Riphah International University 70 participants Est. completion 2025-05-30 2 sites
    Other conditions: Gestational Diabetes Mellitus in Pregnancy
    View official trial listing →
  • Not yet recruiting NCT NCT06452498

    Preeclampsia Intervention Netherlands

    Not yet reported Amsterdam UMC 180 participants Est. completion 2028-07 Stand-alone
    Other conditions: Pre-Eclampsia Onset Less Than 37 Weeks, Pre-Eclampsia, Pre-Eclampsia; Complicating Pregnancy, Pre-Eclampsia as Antepartum Condition, Pre-eclampsia or Eclampsia With Pre-existing Hypertension, Pre-Eclampsia; Affecting Fetus, HELLP Syndrome Complicating Pregnancy, HELLP Syndrome, HELLP
    View official trial listing →
  • Completed NCT NCT06452511

    Comparing the Effect of Metformin vs. Pep2dia as an Adjunct to Letrozole on Ovulation Induction and Pregnancy Outcomes in Overweight Women With PCOS

    Not yet reported Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy 100 participants Est. completion 2025-03-25 1 site
    Other conditions: PCOS
    View official trial listing →
  • Not yet recruiting NCT NCT06460896

    Analysis of the Influence of Gastric By-Pass on the Pharmacokinetics of Common Drugs

    Not yet reported Assistance Publique - Hôpitaux de Paris 64 participants Est. completion 2027-09 1 site
    Other conditions: Bypass Bariatric Surgery
    View official trial listing →
  • Completed NCT NCT06473662

    Study to Evaluate the Safety and Efficacy of Oral Insulin Formulation in Type 2 Diabetes Mellitus Subjects

    Not yet reported Roger New 153 participants Est. completion 2020-07-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06475586

    Effect of Semaglutide on the Psoriatic Lesions in Patients With Type 2 Diabetes Mellitus

    Not yet reported University of Banja Luka 30 participants Est. completion 2024-06-10 1 site
    Other conditions: Psoriasis Vulgaris, Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT06476730

    Telerehabilitation Exercise: Effects on Maternal Psychological Health and Delivery Outcomes

    Not yet reported Riphah International University 62 participants Est. completion 2025-05-10 2 sites
    Other conditions: Gestational Diabetes Mellitus in Pregnancy, Gestational Diabetes, Maternal Psychological Distress
    View official trial listing →
  • Completed NCT NCT06479434

    Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls

    Not yet reported Aga Khan University 110 participants Est. completion 2025-10-02 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT06480292

    Telerehabilitation Exercise: Effects on Maternal Quality of Life, Fetal and Neonatal Health.

    Not yet reported Riphah International University 68 participants Est. completion 2025-06-10 2 sites
    Other conditions: Gestational Diabetes Mellitus in Pregnancy
    View official trial listing →
  • Completed NCT NCT06481085

    To Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus

    Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 324 participants Est. completion 2025-06-30 31 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06483243

    Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetic of CKD-501, D745, and D150 for Healthy Subjects in Fed State.

    Not yet reported Chong Kun Dang Pharmaceutical 45 participants Est. completion 2024-05-17 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT06490874

    Continuous Glucose Monitoring (CGM) Substudy of the DECIDE RCT

    Ohio State University Est. completion 2030-12 4 sites
    Other conditions: Gestational Diabetes Mellitus, Pregnancy, High Risk
    View official trial listing →
  • Status unknown NCT NCT06492655

    To Evaluate the Food Effect on Pharmacokinetic Profiles and Safety in Healthy Volunteers

    Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2024-08-08
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06495281

    Observational Study of Triple Combination Therapy of Zemidapa Tab. and Metformin in Type 2 Diabetes Mellitus Patients

    LG Chem 2044 participants Est. completion 2025-12-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06495931

    Study on Drug Interaction of HRS-1780 Tablets, Henagliflozin Tablets, Metformin Tablets and HRS-7535 Tablets in Healthy Human

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 24 participants Est. completion 2024-08-13 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06504862

    A Study in Healthy Men to Test Whether Zongertinib Influences the Amount of 4 Other Medicines (Dabigatran, Rosuvastatin, Metformin, and Furosemide) in the Blood

    Not yet reported Boehringer Ingelheim 32 participants Est. completion 2024-12-18 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT06515652

    To Compare the Effects of Herbal Medicines With Traditional Allopathic Medicines in Cases of Patients With Metabolic Syndrome

    Not yet reported Hamdard University 200 participants Est. completion 2024-08-30 1 site
    Metabolic syndrome
    View official trial listing →
  • Status unknown NCT NCT06519786

    Safety and Efficacy of Metformin for Treatment of Cytopenia in Children and Adolescents With Fanconi Anemia

    Not yet reported Ain Shams University 30 participants Est. completion 2025-03 2 sites Stand-alone
    Other conditions: Fanconi Anemia
    View official trial listing →
  • Completed NCT NCT06523595

    Evaluation of the Pharmacokinetic Drug-drug Interactions Between VX-993 and Metformin in Healthy Adults

    Not yet reported Vertex Pharmaceuticals Incorporated 31 participants Est. completion 2024-12-31 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Withdrawn NCT NCT06526494

    Metformin and Vascular Function in Prediabetes

    Not yet reported Diana Jalal Est. completion 2025-12-01 2 sites Stand-alone
    Prediabetes
    View official trial listing →
  • Completed NCT NCT06528002

    Hybrid Method Between Low-ratio Premixed Insulin and Short Acting Insulin in Fasting Type 2 Diabetic Patients in Ramadan

    Sohag University 45 participants Est. completion 2024-06-15 1 site
    Other conditions: Continous Blood Glucose Monitoring, Calculation of Body Mass Index, Measurment of Blood Pressure
    View official trial listing →
  • Status unknown NCT NCT06545526

    Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis

    Not yet reported Yonsei University 28 participants Est. completion 2026-06-30 1 site Stand-alone
    Other conditions: Familial Adenomatous Polyposis
    View official trial listing →
  • Status unknown NCT NCT06545994

    A Prospective Cohort Study on the Serum Kisspeptin Levels Throughout Pregnancy in PCOS

    Fudan University 180 participants Est. completion 2026-06-30 1 site
    Other conditions: Polycystic Ovary Syndrome, Pregnancy Complications
    View official trial listing →
  • Status unknown NCT NCT06559722

    A Trial Investigating the Efficacy and Safety of Insulin Degludec/Liraglutide Injection in Subjects With Type 2 Diabetes

    Not yet reported Tonghua Dongbao Pharmaceutical Co.,Ltd 510 participants Est. completion 2026-02 Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT06560333

    iSGLT2 Inhibitor and a iDPP -4 Inhibitor in Treatment of Type 2 Diabetes Mellitus in Patients Treated With Metformin (TRIAD)

    Not yet reported Eurofarma Laboratorios S.A. Est. completion 2029-02-28 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06570980

    Comparative Analysis of Cost-effectiveness Between Sulfonylureas and DPP4 Inhibitors in Combination With Metformin in Treatment of Type 2 Diabetic Patients : A Retrospective, Observational Study.

    Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 200 participants Est. completion 2024-08-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06571591

    Efficacy and Safety of Pioglitazone Combination Therapy in Type 2 Diabetes Patients on a Background of Empagliflozin With Metformin

    Not yet reported Celltrion 606 participants Est. completion 2026-05-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06576375

    Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome

    Not yet reported Future University in Egypt 70 participants Est. completion 2025-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT06589141

    Comparison Between Metformin and Glyburide in the Management of Gestational Diabetes

    Not yet reported Assiut University 180 participants Est. completion 2026-06-30 Stand-alone
    Other conditions: Gestational Diabetes Mellitus in Pregnancy
    View official trial listing →
  • Completed NCT NCT06589765

    A Study of HRS-7535 Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequately Controlled With Metformin

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 810 participants Est. completion 2026-05-29 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06603480

    Effects of Exercise and Metformin on Methylglyoxal Levels in Prediabetic Individuals

    Not yet reported Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey 96 participants Est. completion 2022-12-07 1 site Stand-alone
    Prediabetes Other conditions: Methylglyoxal, Exercise, Metformin
    View official trial listing →
  • Completed NCT NCT06605703

    A Randomized Controlled Trial Comparing the Effectiveness of Different Treatment Options for Weight Management After Discontinuation of Semaglutide and Tirzepatide (GLP1 Transition Trial)

    Not yet reported WW International Inc 226 participants Est. completion 2026-02-05 1 site Stand-alone
    Other conditions: Obesity, Overweight
    View official trial listing →
  • Completed NCT NCT06606886

    Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-Thalassemia

    Not yet reported Bahria University 96 participants Est. completion 2026-02-09 1 site
    Other conditions: Transfusion Dependent Beta-thalassemia
    View official trial listing →
  • Active, not recruiting NCT NCT06611501

    Glycemic Regulation as Endometriosis Adjunct Treatment

    Not yet reported Boston Children's Hospital 14 participants Est. completion 2027-01 1 site Stand-alone
    Other conditions: Pelvic Pain, Endometriosis
    View official trial listing →
  • Status unknown NCT NCT06611904

    The Effect of Combined Dulaglutide and Dapagliflozin Treatment vs DPP-4 Inhibitors in Endothelial and Vascular Function in Patients With Type 2 Diabetes Mellitus and Albuminuria

    Not yet reported Attikon Hospital 60 participants Est. completion 2024-12-15 1 site
    Other conditions: Urine Albumin (UAlb), Glycocalyx, Arterial Stiffness
    View official trial listing →
  • Completed NCT NCT06613750

    Comparative Study of Sitagliptin and Gliclazide With Metformin in Type 2 Diabetes Patients With Glucotoxicity

    Not yet reported Zhibin Xu 129 participants Est. completion 2024-07-01 1 site
    Type 2 diabetes Other conditions: Glucotoxicity
    View official trial listing →
  • Completed NCT NCT06628544

    Trained Immunity in Fungal Infection and Its Mechanism

    Not yet reported Zhongnan Hospital 79 participants Est. completion 2023-12-01 1 site Stand-alone
    Other conditions: BCG Vaccination
    View official trial listing →
  • Completed NCT NCT06638671

    Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity

    Not yet reported University of Virginia 14 participants Est. completion 2026-03-12 1 site Stand-alone
    Other conditions: Exercise Capacity, Metformin
    View official trial listing →
  • Not yet recruiting NCT NCT06644404

    Phase 1 Study of Drug-Drug Interactions Between DWP16001, DWC202407, and DWC202408 in Healthy Adults

    Not yet reported Daewoong Pharmaceutical Co. LTD. 34 participants Est. completion 2025-04-01 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT06649344

    A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 Diabetes

    Not yet reported Fujian Shengdi Pharmaceutical Co., Ltd. 884 participants Est. completion 2026-07-18 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06649773

    The Experiment of Noiiglutide Injection in Type 2 Diabetes Patients

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 137 participants Est. completion 2025-12-11 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06654960

    Influence of HRS9531 on Pharmacokinetics of Metformin in Healthy Subjects

    Not yet reported Fujian Shengdi Pharmaceutical Co., Ltd. 20 participants Est. completion 2024-12-26 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06655220

    A Study in Healthy Men to Test Whether BI 1815368 Influences the Amount of Metformin in the Body

    Not yet reported Boehringer Ingelheim 14 participants Est. completion 2025-01-13 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Enrolling by invitation NCT NCT06666933

    Study of Time-restricted Eating (TRE) to Clinical Pregnancy Rate in PCOS Women With Glucose Metabolism Disorder Via IVF/ICSI

    Not yet reported RenJi Hospital 254 participants Est. completion 2026-07 1 site Stand-alone
    Other conditions: PCOS, Glucose Metabolism Disorder, IVF Outcome
    View official trial listing →
  • Not yet recruiting NCT NCT06670209

    A Phase I Clinical Study to Evaluate the Effect of GZR18 Injection on the Pharmacokinetics of Oral Metformin Hydrochloride Tablets in Overweight/Obese Subjects

    Not yet reported Gan and Lee Pharmaceuticals, USA 32 participants Est. completion 2025-03-19 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06675994

    In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme

    LifeBridge Health 80 participants Est. completion 2025-12-30
    PrediabetesCardiovascular disease Other conditions: Healthy, Hypercholesterolemia, Hypertension, Overweight, Diabetes, Family History of Peripheral Artery Disease, Family History of Cerebrovascular Disease
    View official trial listing →
  • Completed NCT NCT06679413

    A Study to Assess Drug-drug Interaction of ZX008 in Healthy Male and Female Study Participants

    Not yet reported UCB BIOSCIENCES, Inc. 22 participants Est. completion 2025-06-12 1 site Stand-alone
    Other conditions: Healthy Study Participants
    View official trial listing →
  • Not yet recruiting NCT NCT06682351

    Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention

    Not yet reported Stanford University 200 participants Est. completion 2027-12 1 site Stand-alone
    Type 2 diabetesPrediabetes
    View official trial listing →
  • Enrolling by invitation NCT NCT06683235

    Effect of Flaxseed as a Treatment for Adults With Type 2 Diabetes Mellitus in Mexico

    Not yet reported Universidad Autónoma Benito Juárez de Oaxaca 160 participants Est. completion 2025-03 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06688123

    Efficacy and Safety of SHR-3167 and Insulin Glargine in Type 2 Diabetes Subjects

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 275 participants Est. completion 2026-04-22 2 sites
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06691542

    Efficacy and Safety of Platelet-rich Plasma, Metformin and Cryotherapy in Treatment of Non-genital Warts

    Not yet reported, Not yet reported Assiut University 108 participants Est. completion 2025-04 Stand-alone
    Other conditions: Non-Genital Warts
    View official trial listing →
  • Not yet recruiting NCT NCT06713967

    Comparison of Pregnancy Outcomes in Women with Polycystic Ovarian Syndrome with and Without Glucophage

    Not yet reported University of Health Sciences Lahore 70 participants Est. completion 2025-05-26 Stand-alone
    Other conditions: Polycystic Ovarian Syndrome (PCOS), Pregnancy Outcomes
    View official trial listing →
  • Not yet recruiting NCT NCT06717087

    Study of Acupuncture to Control Weight and Improve Pregnancy Rates in Overweight/Obese PCOS Patients

    Not yet reported RenJi Hospital 92 participants Est. completion 2026-06-01 1 site
    Other conditions: Polycystic Ovary Syndrome, Metformin, Acupuncture
    View official trial listing →
  • Completed NCT NCT06727838

    Study on Drug Interaction of Metformin Tablets and HRS-7535 Tablets in Healthy Human

    Not yet reported Shandong Suncadia Medicine Co., Ltd. 18 participants Est. completion 2025-01-25 1 site Stand-alone
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT06728982

    Impact Of Metformin In Rectal Cancer Patients

    Not yet reported, Not yet reported Minia University 85 participants Est. completion 2025-07-15 2 sites
    Other conditions: Rectal Cancer Patients
    View official trial listing →
  • Completed NCT NCT06739044

    Efficacy and Safety of Semaglutide Injection vs Ozempic® in Patients With Type 2 Diabetes

    Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 494 participants Est. completion 2025-02-21 1 site
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06743698

    META Trial - a Mixed Methods Process Evaluation

    University College Dublin 60 participants Est. completion 2027-02
    Prediabetes Other conditions: HIV
    View official trial listing →
  • Completed NCT NCT06759922

    Glimepiride, Empagliflozin, and Sitagliptin With Metformin for Type 2 Diabetes

    Not yet reported Bahria University 172 participants Est. completion 2025-06-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06762041

    Effects of Metformin on Androgens and Other Steroid Hormones in Affected Subjects With Autism

    Insel Gruppe AG, University Hospital Bern 20 participants Est. completion 2026-11-30
    Other conditions: Autism
    View official trial listing →
  • Not yet recruiting NCT NCT06762223

    Henagliflozin on Liver Fibrosis in Patients with MASLD and T2DM

    Not yet reported Xiqiao Zhou 190 participants Est. completion 2026-12-31 1 site Stand-alone
    MASLDType 2 diabetes
    View official trial listing →
  • Completed NCT NCT06766201

    Effect of Use of Calcium Hydroxide and Metformin Intracanal Medicament After NSRCT

    Not yet reported, Not yet reported Postgraduate Institute of Dental Sciences Rohtak 120 participants Est. completion 2025-01-01 1 site Stand-alone
    Other conditions: Apical Periodontitis
    View official trial listing →
  • Completed NCT NCT06766500

    Pharmacokinetics and Bioequivalence Study of Empagliflozin+Metformin Hydrochloride 5 mg/850 mg Film-coated Tablets (Gedeon Richter Plc., Hungary) Versus Synjardy® 5 mg/850 mg Film-coated Tablets (Boehringer Ingelheim International GmbH, Germany)

    Not yet reported Gedeon Richter Plc. 64 participants Est. completion 2025-02-28 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT06772857

    Aerobic Versus Resistance Exercises on Insulin Sensitivity in Obese Patients

    Not yet reported Cairo University 3 participants Est. completion 2025-01-30 1 site Stand-alone
    Other conditions: Insulin Sensitivity/Resistance
    View official trial listing →
  • Enrolling by invitation NCT NCT06773923

    Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration

    Not yet reported Universidad Austral de Chile 10 participants Est. completion 2025-12-01 1 site
    Other conditions: Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures, Bone Loss, Age Related
    View official trial listing →
  • Not yet recruiting NCT NCT06775093

    Effects of GLP-1RAs on Reproductive Outcomes in PCOS and Obesity

    Not yet reported Peking University Third Hospital 392 participants Est. completion 2027-12-31 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Obesity, Infertility, Female
    View official trial listing →
  • Active, not recruiting NCT NCT06778967

    A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus

    Not yet reported Gan & Lee Pharmaceuticals. 1100 participants Est. completion 2026-12-11 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06779253

    A Study to Investigate The Effect of Pimicotinib on The Pharmacokinetics of Metformin, Fexofenadine and Rosuvastatin In Healthy Subjects

    Not yet reported Abbisko Therapeutics Co, Ltd 39 participants Est. completion 2025-05-22 1 site
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT06792968

    Pharmacokinetics and Bioequivalence Study of Empagliflozin+Metformin Hydrochloride 5 mg/1000 mg Film-coated Tablets (Gedeon Richter Plc., Hungary) Versus Synjardy 5 mg/1000 mg Film-coated Tablets (Boehringer Ingelheim International GmbH, Germany)

    Not yet reported Gedeon Richter Plc. 64 participants Est. completion 2025-04-08 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06793943

    A Study of Interaction of Zasocitinib (TAK-279) With Other Medicines in Healthy Adults

    Not yet reported Takeda 78 participants Est. completion 2025-03-30 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Enrolling by invitation NCT NCT06804187

    Sweet Sensing in Type 2 Diabetes

    University of Nottingham 505 participants Est. completion 2026-06 1 site
    Type 2 diabetesPrediabetes
    View official trial listing →
  • Completed NCT NCT06812585

    The Effect of Metformin As an Adjuvant Therapy on Immunological Parameters in Egyptian Patients with RRMS: a Pilot Study

    Not yet reported German University in Cairo 30 participants Est. completion 2025-01-30 1 site Stand-alone
    Other conditions: Multiple Sclerosis (MS) - Relapsing-remitting
    View official trial listing →
  • Completed NCT NCT06813924

    A Research Study of the Effect of Etavopivat on Other Drugs in Healthy Participants

    Not yet reported Novo Nordisk A/S 37 participants Est. completion 2025-05-27 1 site Stand-alone
    Other conditions: Healthy Volunteers Sickle Cell Disease, Thalassemia
    View official trial listing →
  • Completed NCT NCT06823856

    Pharmacokinetics and Bioequivalence Study of Empagliflozin+Metformin Hydrochloride 12.5 mg/1000 mg Film-coated Tablets (Gedeon Richter Plc., Hungary) Versus Synjardy 12.5 mg/1000 mg Film-coated Tablets (Boehringer Ingelheim International GmbH, Germany)

    Not yet reported Gedeon Richter Plc. 64 participants Est. completion 2025-05-21 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06840613

    Glucophage Plus Myo-Inositol vs Glucophage in Glycemic Control Among Patients With Gestational Diabetes Mellitus

    Not yet reported University of Health Sciences Lahore 90 participants Est. completion 2025-05
    Other conditions: Gestational Diabetes Mellitus (GDM)
    View official trial listing →
  • Enrolling by invitation NCT NCT06846138

    Enhancing the Efficacy and Tolerability of Metformin by add-on Polyherbal Formulation: a Gut Microbiome Study

    Not yet reported Pauls Stradins Clinical University Hospital 66 participants Est. completion 2026-12-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06851962

    Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.

    Not yet reported Fundación para la Investigación del Hospital Clínico de Valencia 92 participants Est. completion 2026-06-30 3 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT06856369

    Clinical Efficacy of 1% Metformin and Alendronate Gel in Adjunct to Fibrin in Chronic Periodontitis

    Not yet reported Bahria University 120 participants Est. completion 2027-09-30 1 site
    Other conditions: Alveolar Bone Loss Associated Chronic Periodontitis
    View official trial listing →
  • Active, not recruiting NCT NCT06860841

    Effects of D-Chiro-Inositol Combined with Metformin on Insulin Resistance in People with Overweight or Obesity and T2DM

    Not yet reported Campus Bio-Medico University 16 participants Est. completion 2025-04-10 1 site Stand-alone
    Type 2 diabetes Other conditions: Overweight and Obese Adults
    View official trial listing →
  • Completed NCT NCT06871761

    A Trial Comparing HR17031 With Insulin Glargine in Patients With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 393 participants Est. completion 2025-05-13 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06871904

    Fibrosis-Modulating Effects of Metformin and Pirfenidone in Oral Submucous Fibrosis

    Not yet reported, Not yet reported Ziauddin University 45 participants Est. completion 2025-12-30 1 site Stand-alone
    Other conditions: Oral Submucous Fibrosis
    View official trial listing →
  • Completed NCT NCT06881264

    A Study Comparing HR17031 With Insulin Glargine in Patients With Type 2 Diabetes

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 401 participants Est. completion 2025-09-19 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06882291

    Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S

    Not yet reported Cairo University 72 participants Est. completion 2025-09-30 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Terminated NCT NCT06884683

    Nivolumab Plus Metformin in Metastatic Renal Cell Carcinoma

    Not yet reported Fondazione Policlinico Universitario Agostino Gemelli IRCCS 12 participants Est. completion 2023-09-13 2 sites Stand-alone
    Other conditions: Metastatic Renal Cell Carcinoma
    View official trial listing →
  • Not yet recruiting NCT NCT06893978

    Placental Organoids Development: Application in the Study of the Human Reproduction Pathophysiology.

    Fondazione Policlinico Universitario Agostino Gemelli IRCCS 20 participants Est. completion 2027-11 1 site
    Other conditions: Preeclampsia, Pregnancy Loss, Preterm Birth, Healthy
    View official trial listing →
  • Active, not recruiting NCT NCT06899061

    Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib

    Not yet reported AstraZeneca 41 participants Est. completion 2028-05-19 4 sites
    Other conditions: Advanced Solid Malignancies
    View official trial listing →
  • Active, not recruiting NCT NCT06907472

    Diabetes Management for Primary Healthcare Centers.

    Not yet reported University of Abuja 106 participants Est. completion 2026-12-31 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06911983

    Comparative Efficacy of Metformin and Berberine Among TCF7L2 (rs7903146) TT vs. CC Genotype Carriers With Type 2 Diabetes

    Not yet reported S.LAB (SOLOWAYS) 60 participants Est. completion 2026-03-01 1 site
    Other conditions: Diabetes Mellitis
    View official trial listing →
  • Completed NCT NCT06913881

    Comparative Cardiovascular Effectiveness of GLP-1 RAs vs. Insulin in Early-Onset Type 2 Diabetes

    Karolinska Institutet 92100 participants Est. completion 2025-01-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT06920056

    A Study of BGM0504 in Overweight or Obese Participants

    Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 28 participants Est. completion 2025-07-25 1 site Stand-alone
    Other conditions: Overweight or Obese
    View official trial listing →
  • Not yet recruiting NCT NCT06942390

    Topical Metformin Versus Topical Ketotifen in Melasma Treatment

    Not yet reported Assiut University 60 participants Est. completion 2026-10-30 Stand-alone
    Other conditions: Melasma
    View official trial listing →
  • Not yet recruiting NCT NCT06946628

    New Triple Therapy in Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 296 participants Est. completion 2030-12-31 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Enrolling by invitation NCT NCT06959784

    Assessing Incretin Therapy for Cardiovascular Risk Reduction and Diabetes Remission( ITCRDR Study)

    Not yet reported China-Japan Friendship Hospital 142 participants Est. completion 2026-12-31 1 site
    Cardiovascular disease Other conditions: Diabetes Mellitus, Cerebrovascular Disease
    View official trial listing →
  • Completed NCT NCT06961019

    Clinical Study to Assess the Safety, Efficacy and In-Use Tolerability of Herbal-Based Sugar Support Effervescent Tablets in Type-2 Diabetes Mellitus Patients

    Not yet reported NovoBliss Research Pvt Ltd 14 participants Est. completion 2026-03-14 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT06965868

    Role of the Blood-Brain Barrier in Stress Resilience: Investigating New Pathways Towards Pharmacological Augmentation of Stress Resilience

    Not yet reported Leibniz-Institut für Resilienzforschung (LIR) gGmbH 122 participants Est. completion 2027-02 3 sites
    Other conditions: Stress Resilience, Blood-Brain Barrier Integrity, Mental Health
    View official trial listing →
  • Not yet recruiting NCT NCT06975839

    Local Metformin Gel and Impacted Lower Third Molar

    Not yet reported Fayoum University 36 participants Est. completion 2026-02-01 Stand-alone
    Other conditions: Impacted Third Molar Tooth
    View official trial listing →
  • Completed NCT NCT06983223

    Oral Sucrosomial® Vitamin B12 in the Management of B12 Deficiency Among Metformin-Treated Type 2 Diabetes Patients

    Not yet reported Liaquat University of Medical & Health Sciences 50 participants Est. completion 2025-12-03 1 site
    Type 2 diabetes Other conditions: Vitamin B 12 Deficiency
    View official trial listing →
  • Completed NCT NCT06995339

    Comparative Clinical and Biochemical Study Evaluating the Effectiveness of Metformin Versus Febuxostat on Gouty Obese Non-Diabetic Patients

    Not yet reported Mostafa Bahaa 60 participants Est. completion 2025-12-30 1 site
    Other conditions: Gout
    View official trial listing →
  • Not yet recruiting NCT NCT06999343

    Exploring the Anti-ageing Effects of Metformin in COPD

    Not yet reported Fundación Instituto de Investigación Sanitaria de Navarra 212 participants Est. completion 2029-09-01 Stand-alone
    Other conditions: COPD
    View official trial listing →
  • Active, not recruiting NCT NCT07003191

    Metformin Hydrochloride and Empagliflozin Tablets in the Treatment of Type 2 Diabetes

    Sun Yat-sen University 2600 participants Est. completion 2025-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT07007221

    Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV

    Not yet reported University of Minnesota Est. completion 2030-12-01 Stand-alone
    Other conditions: Depression, Hiv
    View official trial listing →
  • Active, not recruiting NCT NCT07026968

    A Study of Prusogliptin Tablets Combined With Dapagliflozin Tablets and Metformin Hydrochloride Extended Release Tablets in Type 2 Diabetes

    Not yet reported CSPC Ouyi Pharmaceutical Co., Ltd. 815 participants Est. completion 2026-11-13 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07027969

    Metabolic Surgery for Atrial Fibrillation Elimination

    Not yet reported Ali Aminian 100 participants Est. completion 2030-03-31 1 site
    Other conditions: Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
    View official trial listing →
  • Active, not recruiting NCT NCT07033585

    Generic Drugs (Dapagliflozin and Saxagliptin) Treat Type 2 Diabetes Patients With Controlled Cancers

    Not yet reported, Not yet reported Han Xu, M.D., Ph.D., FAPCR, Medical Director,, IRB Chair 600 participants Est. completion 2026-11-28 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT07055958

    Effect of Metformin as Add-on Therapy in Levodopa Treated Parkinson's Disease Patients

    Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 74 participants Est. completion 2025-07-20 1 site Stand-alone
    Other conditions: Parkinson Disease
    View official trial listing →
  • Completed NCT NCT07057271

    A Study of CJC-1134-PC Injection in Patients With Type 2 Diabetes With Inadequately Controlled Blood Glucose Level After Metformin Monotherapy or Metformin in Combination With Insulin Secretagogues

    Not yet reported Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd. 464 participants Est. completion 2023-02-21 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT07057479

    Phase III Trial of SGLT2 Inhibitor and Thiazolidinedione Fixed-Dose Combination vs. Monotherapy in Type 2 Diabetes Patients on Metformin

    Not yet reported Eurofarma Laboratorios S.A. Est. completion 2028-02 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07058675

    Myoinositol vs. Metformin for Polycystic Ovarian Syndrome (PCOS): Impact on Metabolic Health and Fertility

    Not yet reported Benha University 156 participants Est. completion 2025-06-18 1 site
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT07061496

    Comparative Effects of Exercise and Metformin on Glycemic Control in Prediabetic Adults

    Not yet reported Asad Ullah Jan 226 participants Est. completion 2026-03-15 1 site
    Other conditions: Pre Diabetic, Pre Diabetes
    View official trial listing →
  • Completed NCT NCT07066722

    A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults

    Not yet reported ViiV Healthcare 126 participants Est. completion 2025-12-17 2 sites Stand-alone
    Other conditions: HIV Infections
    View official trial listing →
  • Completed NCT NCT07072949

    The Impact of Ursodeoxycholic Acid and Probiotics on Metabolic Outcomes in Type 2 Diabetic Patients Taking Metformin

    Not yet reported University of Banja Luka 90 participants Est. completion 2024-01-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07073157

    Effect of HRS-8427 for Injection on the Pharmacokinetics of Furosemide and Metformin in Healthy Subjects。

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 24 participants Est. completion 2025-08-15 1 site Stand-alone
    Other conditions: Health Volunteer
    View official trial listing →
  • Enrolling by invitation NCT NCT07073768

    Comparison Between Efficacy of Trelagliptin and Sitagliptin in Type II Diabetic Patients

    Not yet reported Khyber Medical College, Peshawar 126 participants Est. completion 2026-12-30 1 site Stand-alone
    Type 2 diabetes Other conditions: Glycemic Control for Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT07076056

    Clinical Trial to Evaluate the Efficacy and Safety of DW1026C1 or DW1026C2

    Not yet reported Daewon Pharmaceutical Co., Ltd. 230 participants Est. completion 2024-06-19 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07077525

    Effect of Vildagliptin Versus Dapagliflozin as Add on Therapy to Metformin on Cardiovascular Risk Factors

    Not yet reported Al-Azhar University 196 participants Est. completion 2024-08-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07086859

    Alveolar Ridge Preservation Using Autogenous Whole Tooth Graft With 1 %Metformin :A Randomized Controlled Clinical Trial

    Not yet reported Cairo University 24 participants Est. completion 2026-03-30 1 site Stand-alone
    Other conditions: Dimensional Changes After Tooth Extraction, Tooth Extraaction, Socket Preservation
    View official trial listing →
  • Not yet recruiting NCT NCT07088523

    Traditional Chinese Medicine Intervention for Ischemic Cardiovascular Disease Comorbid With Diabetes Mellitus: An Efficacy Comparative Study

    Not yet reported Guangzhou University of Traditional Chinese Medicine 4205 participants Est. completion 2027-12-31 1 site
    Cardiovascular disease Other conditions: Diabete Mellitus
    View official trial listing →
  • Not yet recruiting NCT NCT07113756

    New Topical Treatment in Plaque Psoriasis

    Not yet reported Sohag University 70 participants Est. completion 2026-09-01
    Other conditions: Plaque Psoriasis
    View official trial listing →
  • Completed NCT NCT07120828

    The Role of CYP8B1 Polymorphisms in Modulating the Biochemical Pathways Affected by SGLT2 Inhibitors in T2DM and Obesity

    Not yet reported Erbil Polytechnic University 260 participants Est. completion 2026-03-15 1 site
    Type 2 diabetes Other conditions: Obese Diabetics, Obese Patients (BMI ≥ 30 kg/m²)
    View official trial listing →
  • Not yet recruiting NCT NCT07121088

    Traditional Chinese Medicine Intervention for Ischemic Cerebrovascular Disease and Diabetes Mellitus: An Efficacy Comparative Study

    Not yet reported Guangzhou University of Traditional Chinese Medicine 3666 participants Est. completion 2027-12-31
    Other conditions: Ischemic Cerebral Infarction, Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT07121959

    A Study of Belzutifan (MK-6482) and Metformin in Healthy Adult Participants (MK-6482-039)

    Not yet reported Merck Sharp & Dohme LLC 14 participants Est. completion 2025-09-26 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Not yet recruiting NCT NCT07136987

    A Trial of 2 Disease-Modifying Drugs (Metformin and N-acetylcysteine ) to Promote TB Lung Function Recovery

    Not yet reported Open Source Pharma Foundation 1104 participants Est. completion 2031-07 Stand-alone
    Other conditions: Tuberculosis
    View official trial listing →
  • Not yet recruiting NCT NCT07139405

    TriGlytza®-01 Versus Metformin in Overweight and Obese Adults With Type 2 Diabetes and Inadequate Glycaemic Control Despite Metformin Therapy

    Not yet reported Myopharm Limited 48 participants Est. completion 2027-12-30 3 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07145827

    Effect of Metformin on Endometrial Thickness in Postmenopausal Breast Cancer Patients Receiving Tamoxifen

    Not yet reported Uruk University 60 participants Est. completion 2025-07-01 1 site Stand-alone
    Other conditions: Breast Cancer, Endometrial Hyperplasia and Endometrial Cancers
    View official trial listing →
  • Not yet recruiting NCT NCT07156539

    A Phase 3 Study of HS-20094 in Patients With T2DM

    Not yet reported Jiangsu Hansoh Pharmaceutical Co., Ltd. 546 participants Est. completion 2027-05-30 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07158411

    Evaluate the Effect of Vimseltinib on Organic Cation Transporter 2 (OCT2)

    Not yet reported Deciphera Pharmaceuticals, LLC 22 participants Est. completion 2026-01-30 1 site Stand-alone
    Other conditions: Healthy Participants
    View official trial listing →
  • Not yet recruiting NCT NCT07165158

    The Effect of Semaglutide on Bone Health

    Not yet reported The First Affiliated Hospital of Xiamen University 150 participants Est. completion 2026-12-31 1 site Stand-alone
    Type 2 diabetes Other conditions: Osteoporosis, Osteoporosis Fracture
    View official trial listing →
  • Completed NCT NCT07172269

    Mangosteen Supplement as Adjuvant Therapy With Sitagliptin/Metformin in Iraqi Patients With Type 2 Diabetes

    Not yet reported Mais Qais Hbeeb 58 participants Est. completion 2025-05-26 1 site Stand-alone
    Type 2 diabetes Other conditions: Diabete Mellitus, Dyslipidemia in Patients With Diabetes Mellitus, Insulin Resistance
    View official trial listing →
  • Not yet recruiting NCT NCT07173712

    Regimen Transition After Short-Term Intensive Insulin Therapy in Type 2 Diabetes

    Not yet reported Yanbing Li 324 participants Est. completion 2027-12-31
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT07176338

    Role of Metformin in Posterior Capsule Opacification

    Not yet reported Vienna Institute for Research in Ocular Surgery 40 participants Est. completion 2025-10-01 1 site Stand-alone
    Type 2 diabetes Other conditions: Cataract
    View official trial listing →
  • Enrolling by invitation NCT NCT07179042

    Intertrochanteric Femur Fracture Patients Who Receive Metformin With a Placebo

    Not yet reported University of Utah 60 participants Est. completion 2030-09 1 site Stand-alone
    Other conditions: Intertrochanteric Femur Fracture, Muscle Atrophy
    View official trial listing →
  • Enrolling by invitation NCT NCT07209527

    Truway Diagnostic Tools in Primary Care

    Not yet reported Truway Health, Inc. 200 participants Est. completion 2028-10-01 1 site Stand-alone
    Type 2 diabetesCardiovascular diseaseChronic kidney diseaseMetabolic syndromePrediabetes Other conditions: Chronic Disease, Hypertension, Hyperlipidemia, Peripheral Artery Disease
    View official trial listing →
  • Completed NCT NCT07213895

    Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCL 25mg/5mg/1000mg Extended-Release Tablets Versus Trijardy® XR Extended Release Film Coated Tablets

    Not yet reported Humanis Saglık Anonim Sirketi 14 participants Est. completion 2025-09-18 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07215156

    Metformin Versus Chlorhexidine Gel as Adjuncts to Scaling and Root Planing in Stage II Grade B Periodontitis

    Not yet reported Kafrelsheikh University 60 participants Est. completion 2026-06-01 Stand-alone
    Other conditions: Stage II, Grade B Periodontitis, Chronic Periodontitis
    View official trial listing →
  • Completed NCT NCT07216131

    A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years

    Not yet reported AstraZeneca 14 participants Est. completion 2025-12-30 1 site Stand-alone
    Other conditions: Healthy Participants
    View official trial listing →
  • Completed NCT NCT07222098

    A Clinical Study of Calderasib (MK-1084) With Rosuvastatin and Metformin in Healthy People (MK-1084-016)

    Not yet reported Merck Sharp & Dohme LLC 16 participants Est. completion 2025-12-29 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT07223671

    Study to Evaluate the Effect of Repotrectinib on the Drug Levels of Transporter and CYP P450 Probe Substrates in Healthy Adult Participants

    Not yet reported Bristol-Myers Squibb 30 participants Est. completion 2026-03-19 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Not yet recruiting NCT NCT07229534

    Clinical Trial to Evaluate the Efficacy and Safety of DA-5218 in Patients With Type 2 Diabetes

    Not yet reported Dong-A ST Co., Ltd. 238 participants Est. completion 2027-11
    Other conditions: Diabete Mellitus
    View official trial listing →
  • Not yet recruiting NCT NCT07241897

    DPP4 Inhibitor Intervention on Post-stroke Cognitive Impairment in Ischemic Stroke Patients With Type 2 Diabetes

    Not yet reported Second Affiliated Hospital of Soochow University 312 participants Est. completion 2028-04-30 1 site Stand-alone
    Cardiovascular disease Other conditions: Diabete Mellitus
    View official trial listing →
  • Active, not recruiting NCT NCT07244770

    The Effects of Some Antihyperglycemic Drugs on Cognitive Function and Risk of Depression of Diabetic Patients

    Beni-Suef University 300 participants Est. completion 2026-12-30 1 site
    Other conditions: MCI
    View official trial listing →
  • Completed NCT NCT07247656

    The Efficacy and Safety of Empagliflozin - Linagliptin and Empagliflozin- Metformin Therapy in Reduction of Body Weight in Type 2 Diabetic Patients .

    Not yet reported Bahria University 200 participants Est. completion 2023-05-01 1 site
    Other conditions: Diabete Mellitus
    View official trial listing →
  • Completed NCT NCT07266766

    Bioequivalence Study to Compare Empagliflozin / Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg

    Not yet reported Humanis Saglık Anonim Sirketi 40 participants Est. completion 2025-10-06 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07266779

    Bioequivalence Study of Test Product (T) of Ertugliflozin/Metformin 7.5 mg/ 1000 mg Film Coated Tablets and Reference Product (R) of Segluromet 7.5 mg/ 1000 mg Film Coated Tablets in Healthy, Adult, Human Subjects Under Fed Condition.

    Not yet reported Humanis Saglık Anonim Sirketi 36 participants Est. completion 2025-10-11 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07272109

    Active Anti-diabetic Treatment Plus Chemotherapy for Pancreatic Cancer Related Diabetes

    Not yet reported Fudan University 210 participants Est. completion 2028-12-30 1 site Stand-alone
    Other conditions: Pancreatic Cancer
    View official trial listing →
  • Not yet recruiting NCT NCT07272967

    Metformin in Preventing Secondary Gliosis Following Acute Thoraco-Lumbar Spinal Cord Injury

    Not yet reported Badr University 34 participants Est. completion 2026-02-01 1 site
    Other conditions: Spinal Cord Injury (SCI)
    View official trial listing →
  • Active, not recruiting NCT NCT07274644

    Effects of iGlarLixi Versus iGlar on Liver Fat Content in Patients With Type 2 Diabetes Mellitus Combined With Metabolic Dysfunction-associated Steatotic Liver Disease

    Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 36 participants Est. completion 2026-07-30 1 site Stand-alone
    MASLDType 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07275359

    Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations

    Not yet reported Duke University 45 participants Est. completion 2029-10-02 1 site Stand-alone
    Other conditions: Chronic Obstructive Pulmonary Disease (COPD)
    View official trial listing →
  • Active, not recruiting NCT NCT07279909

    Phase-III Clinical Studies on Poly Herbal Anti-Diabetic Formulation

    Not yet reported Hamdard University 500 participants Est. completion 2026-05-20 1 site
    Other conditions: Diabetes Type 2, Diabetes Mellitus, Experimental, HbA1c, Urinary Glucose, Ability of Experimental Drug to Lower HbA1c Compare to Metformin
    View official trial listing →
  • Enrolling by invitation NCT NCT07280572

    RECLAIM Adaptive Platform Trial for PCC Treatments

    Not yet reported Janneke van de Wijgert 1250 participants Est. completion 2027-12-01 1 site Stand-alone
    Other conditions: Post COVID Condition
    View official trial listing →
  • Not yet recruiting NCT NCT07289750

    The Effect of Alogliptin Combined With Actoplus Met on Glucose and Lipid Metabolism and Pancreatic Function in Patients With T2DM Complicated With MAFLD

    Not yet reported The Fourth Affiliated Hospital of Zhejiang University School of Medicine 80 participants Est. completion 2027-08-31
    Type 2 diabetes Other conditions: MAFLD
    View official trial listing →
  • Not yet recruiting NCT NCT07300007

    PK and Relative Bioavailability of Liquid Metformin vs Tablets in Healthy Adults

    Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-05-28 Stand-alone
    Other conditions: Healthy Volunteer
    View official trial listing →
  • Not yet recruiting NCT NCT07300020

    PK and Relative Bioavailability of Novel Liquid Metformin vs Tablets

    Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-06-28 Stand-alone
    Other conditions: Healthy Volunteer
    View official trial listing →
  • Not yet recruiting NCT NCT07300033

    Bioequivalence Study of Liquid Metformin (100 and 250 mg/mL) vs IR Tablets

    Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-07-28 Stand-alone
    Other conditions: Healthy Volunteer
    View official trial listing →
  • Not yet recruiting NCT NCT07300046

    Tolerability Study of Liquid Metformin (100 and 250 mg/mL) vs IR Tablets

    Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-08-28 Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Not yet recruiting NCT NCT07300059

    Short-Term Glycemic Effects of Liquid Metformin vs Standard Tablets

    Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-08-28 Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT07302932

    Metformin and Molecular Aging in Prediabetes

    Not yet reported Diabetes Foundation, India 112 participants Est. completion 2025-01-30 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Completed NCT NCT07303127

    Combination of Bitter Melon Extract and Snakehead Fish Powder to Reduce Glycaemia in Type 2 Diabetes Mellitus

    Not yet reported Universitas Muhammadiyah Surakarta 80 participants Est. completion 2021-10-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT07303556

    Improving Cardiovascular Disease Diagnosis and Treatment in Kazakhstan Using Metabolic Correction With GLP-1 Drugs

    Not yet reported Nazarbayev University 120 participants Est. completion 2026-11-01 1 site Added to GLP-1
    Heart failure Other conditions: Diabete Type 2, Arterial Hypertension
    View official trial listing →
  • Not yet recruiting NCT NCT07311551

    A Comparison of Effectiveness, Safety, and Cost-effectiveness of Dapagliflozin and Empagliflozin in Patients With Type 2 Diabetes Mellitus and High Body Mass Index (BMI)

    Not yet reported Bhavya Bhavya, MD 112 participants Est. completion 2026-12 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT07321223

    Comparison of Different Doses of Vitamin D Supplementation on Glycated Haemoglobin and Blood Glucose Parameters With Type II Diabetes Mellitus Having Vitamin d Deficiency

    Not yet reported University of Lahore 108 participants Est. completion 2026-02-22 1 site
    Other conditions: Diabetes (DM), Vitamin D Deficiency
    View official trial listing →
  • Not yet recruiting NCT NCT07323381

    Effects of Henagliflozin Proline and Metformin XR on Body Composition in Geriatric Patients With Newly Diagnosed T2DM

    Not yet reported Bin Lu 116 participants Est. completion 2027-09-30
    Other conditions: Diabetes Type 2
    View official trial listing →
  • Completed NCT NCT07323589

    Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS

    Not yet reported PAEC general hospital 120 participants Est. completion 2025-10-25 1 site Stand-alone
    Other conditions: PCOS (Polycystic Ovary Syndrome)
    View official trial listing →
  • Completed NCT NCT07333742

    A Clinical Study to See How the Body Handles and How Safe a Combination Tablet of Gemigliptin, Dapagliflozin, and Metformin 50/10/1000mg is Compared to Taking Gemigliptin 50mg Separately With Dapagliflozin/Metformin 10/1000mg in Healthy Adults After a Meal

    Not yet reported LG Chem 50 participants Est. completion 2025-11-27 1 site Stand-alone
    Other conditions: Fed Conditions, Healthy Volunteer
    View official trial listing →
  • Completed NCT NCT07336914

    Effect of Conventional vs Intensive Management on Gestational Diabetes and Maternal Fetal Outcomes

    Not yet reported Khyber Medical University Peshawar 60 participants Est. completion 2026-04-25 2 sites Stand-alone
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07342764

    Dapagliflozin Versus Metformin for the Management of Antipsychotic-Induced Weight Gain: A Pragmatic Pilot Randomized Controlled Trial

    Not yet reported Sultan Qaboos University 110 participants Est. completion 2028-12 1 site
    Other conditions: Antipsychotic-induced Weight Gain (AIWG), Antipsychotic-induced Weight Gain
    View official trial listing →
  • Completed NCT NCT07345507

    Comparison of Efficacy of Metformin Gel 30% vs Triple Combination Cream (Hydroquinone 4%, Flucinolone Acetonide 0.01%, Tretinoin 0.025%) in Treatment of Melasma in Tertiary Care Hospital Karachi

    Not yet reported Jinnah Postgraduate Medical Centre 34 participants Est. completion 2025-08-30 1 site Stand-alone
    Other conditions: Melasma
    View official trial listing →
  • Completed NCT NCT07357337

    Efficacy of Oral Metformin vs Oral Doxycycline in Treating Acne Vulgaris

    Not yet reported Ghurki Trust and Teaching Hospital 68 participants Est. completion 2025-10-01 1 site Stand-alone
    Other conditions: Acne Vulgaris on the Face, Acne Vulgaris
    View official trial listing →
  • Active, not recruiting NCT NCT07362030

    Drug-durg Interaction of RAY1225 With Warfarin, Atorvastatin, Metformin and Digoxin

    Not yet reported Guangdong Raynovent Biotech Co., Ltd 32 participants Est. completion 2026-03-30 1 site Stand-alone
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT07363707

    A Study Between Dapagliflozin and Empagliflozin Effect on NAFLD in Patients With Type 2 Diabetes.

    Not yet reported Beni-Suef University 108 participants Est. completion 2024-03-01 1 site
    MASLD
    View official trial listing →
  • Not yet recruiting NCT NCT07365358

    Evaluate the Efficacy and Safety of Empagliflozin or Glimepiride Combination Therapy in Type 2 Diabetes Mellitus Patients

    Not yet reported Chong Kun Dang Pharmaceutical 200 participants Est. completion 2027-08 1 site
    Other conditions: Diabete Type 2
    View official trial listing →
  • Completed NCT NCT07368569

    A Study in Healthy People to Test Whether BI 764198 Influences the Amount of Metformin in the Body

    Not yet reported Boehringer Ingelheim 14 participants Est. completion 2026-03-17 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT07372118

    Bioequivalence Study to Compare Empagliflozin / Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg in Fast Condition

    Not yet reported Humanis Saglık Anonim Sirketi 32 participants Est. completion 2026-01-07 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07375654

    Combined Use of Cyclosporine and Metformin in Treatment of Psoriasis vs Cyclosporine Alone

    Not yet reported Cairo University 32 participants Est. completion 2025-11-04 1 site
    Other conditions: Psoriasis
    View official trial listing →
  • Completed NCT NCT07380841

    Metformin vs Inositol vs Diet vs Combination Therapy in PCOS

    Not yet reported Islamabad Medical and Dental College 192 participants Est. completion 2026-01-13 1 site Stand-alone
    Metabolic syndrome Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Completed NCT NCT07387679

    Myo-inositol Versus Metformin in Patients With Polycystic Ovarian Syndrome to Treat Obesity

    Not yet reported Muhammad Aamir Latif 60 participants Est. completion 2025-05-28 1 site Stand-alone
    Other conditions: Polycystic Ovarian Syndrome
    View official trial listing →
  • Not yet recruiting NCT NCT07395895

    Effect of Metformin Iontophoresis on Knee Osteoarthritis in Postmenopausal Women

    Not yet reported Badr University 68 participants Est. completion 2026-05-01 1 site
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT07396844

    The Food Effect on Pharmacokinetics of Fixed Dose Combination of Gemigliptin/Dapagliflozin/Metformin in Healthy Volunteers

    Not yet reported LG Chem 28 participants Est. completion 2026-06-26 1 site Stand-alone
    Other conditions: Healthy, Fasting, Fed
    View official trial listing →
  • Completed NCT NCT07399470

    A Clinical Study in Healthy Adults to See How the Body Processes and How Safe a Tablet That Combines Gemigliptin, Dapagliflozin, and Metformin is, Compared With Taking Zemiglo and Xigduo XR Together While Fasting.

    Not yet reported LG Chem 58 participants Est. completion 2026-02-06 1 site Stand-alone
    Other conditions: Healthy Volunteers, Fasting Conditions
    View official trial listing →
  • Completed NCT NCT07399535

    Clinical Investigation of Herbal Formulation and Its Efficacy in Polycystic Ovarian Syndrome

    Not yet reported Jinnah Postgraduate Medical Centre 116 participants Est. completion 2026-03-01 1 site Stand-alone
    Other conditions: Polycystic Ovarian Syndrome (PCOS), Herbal Medicine, Infertility, Metabolic Disorder
    View official trial listing →
  • Completed NCT NCT07412015

    Pilot Bioequivalence Study of Chiglitazar/Metformin Extended-Release Tablets

    Not yet reported Chipscreen Biosciences, Ltd. 24 participants Est. completion 2026-05-28 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07415226

    Glucose-lowering Drugs as an Adjunct to Insulin Therapy in Chinese Patients With Type 1 Diabetes

    Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 500 participants Est. completion 2027-12-31
    Other conditions: Type 1 Diabetes Mellitus
    View official trial listing →
  • Not yet recruiting NCT NCT07417306

    A Study of HDM1005 in Participants With T2DM Not Controlled With Metformin Alone or in Combination With a Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor

    Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 912 participants Est. completion 2027-12-31 1 site
    Type 2 diabetes
    View official trial listing →
  • Suspended NCT NCT07433062

    A Study to Evaluate the Effect of AZD6793 on the Pharmacokinetics and Pharmacodynamics of Metformin in Participants With Type 2 Diabetes Mellitus

    Not yet reported AstraZeneca 28 participants Est. completion 2026-06-18 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07436182

    Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. Metformin Monotherapy

    Not yet reported Mansoura University 176 participants Est. completion 2026-06-01 1 site Stand-alone
    Other conditions: Mitochondria, Metformin
    View official trial listing →
  • Completed NCT NCT07437612

    Cryotherapy and Intracanal Medicaments for Postoperative Pain in Apical Periodontitis

    Not yet reported Celalettin Topbaş 80 participants Est. completion 2024-01-01 1 site
    Other conditions: Symptomatic Apical Periodontitis, Pulp Necrosis
    View official trial listing →
  • Not yet recruiting NCT NCT07441187

    Efficacy and Safety of Henagliflozin, Retagliptin, and Metformin Extended-Release Tablets in Chinese Patients With Type 2 Diabetes Mellitus

    Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 300 participants Est. completion 2027-12-31
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07451639

    White Mulberry Leaf Extract for Metabolic Health in Overweight Adults Taking Metformin

    Not yet reported Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo 50 participants Est. completion 2024-06-01 1 site
    Other conditions: Weight Management
    View official trial listing →
  • Completed NCT NCT07451938

    A Cohort Study on Obese Patients' Multidisciplinary Integrated Health Management

    China-Japan Friendship Hospital 1500 participants Est. completion 2025-07-30 1 site
    Other conditions: Obesity, Diabete Type 2, Bariatric Surgery
    View official trial listing →
  • Enrolling by invitation NCT NCT07452913

    Metformin, Empagliflozin With Sitagliptin vs Linagliptin in Type 2 Diabetes

    Not yet reported Bahria University 110 participants Est. completion 2026-06-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07459595

    Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study

    Not yet reported Fatima Tariq 60 participants Est. completion 2026-07-31 1 site
    Other conditions: Polycystic Ovarian Syndrome (PCOS)
    View official trial listing →
  • Not yet recruiting NCT NCT07460336

    Effects of Cofrogliptin on Beta-Cell Function in LADA Patients

    Not yet reported Second Xiangya Hospital of Central South University 84 participants Est. completion 2027-12-31 1 site Stand-alone
    Other conditions: Latent Autoimmune Diabetes in Adults (LADA)
    View official trial listing →
  • Completed NCT NCT07462078

    The Effect of Lifestyle Modification on the Risk of Prediabetes Among Patients Attending Outpatient Clinic.

    Not yet reported Kasr El Aini Hospital 124 participants Est. completion 2025-06-02 1 site Stand-alone
    Prediabetes
    View official trial listing →
  • Completed NCT NCT07469254

    Adding 1% Metformin Gel to Bone Graft in Association With Immediate Dental Implants

    Not yet reported Al-Azhar University 20 participants Est. completion 2025-09-01 1 site Stand-alone
    Other conditions: Metformin Gel, Bone Graft, Immediate Dental Implants
    View official trial listing →
  • Completed NCT NCT07472179

    Effect of Pioglitazone vs Metformin on Clinical, Biochemical and Hormonal Parameters of Insulin Resistant PCOS

    Not yet reported Mst.Sumyara Khatun 60 participants Est. completion 2026-02-20 1 site Stand-alone
    Other conditions: PCOS(Insulin Resistant)
    View official trial listing →
  • Active, not recruiting NCT NCT07475546

    Combination Gerotherapeutic Interventions for Healthspan Improvement

    Not yet reported AgelessRx 30 participants Est. completion 2026-04 1 site Stand-alone
    Other conditions: Healthspan Improvement, Aging, Longevity
    View official trial listing →
  • Not yet recruiting NCT NCT07485777

    Comparative Evaluation of Topical 30% Metformin and Kligman's Regimen in Women With Melasma

    Not yet reported Foundation University Islamabad 82 participants Est. completion 2027-06-01 1 site Stand-alone
    Other conditions: Melasma (Facial Melasma), Melasma
    View official trial listing →
  • Not yet recruiting NCT NCT07487103

    Efficacy and Safety of QLG1091 vs Rybelsus as add-on to Metformin in Subjects With Type 2 Diabetes

    Not yet reported Qilu Pharmaceutical Co., Ltd. 478 participants Est. completion 2027-05
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07495748

    Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma

    Not yet reported Foundation University Islamabad 70 participants Est. completion 2027-07-01 1 site Stand-alone
    Other conditions: Melasma
    View official trial listing →
  • Not yet recruiting NCT NCT07502001

    Influence of HDM1005 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin

    Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 42 participants Est. completion 2027-06-02 1 site Stand-alone
    Other conditions: Overweight, Obesity
    View official trial listing →
  • Not yet recruiting NCT NCT07511010

    Food Effect and Multiple-Dose Study of Chiglitazar/Metformin Extended-Release Tablets

    Not yet reported Chipscreen Biosciences, Ltd. 28 participants Est. completion 2026-10-26 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07513480

    Pretreatment With CPA-EE, Metformin and Myoinositol in PCOS With High AMH

    Not yet reported Mst.Sumyara Khatun 68 participants Est. completion 2026-02-20 1 site Stand-alone
    Other conditions: PCOS
    View official trial listing →
  • Not yet recruiting NCT NCT07516821

    Efficacy of Topical Metformin in Psoriasis Vulgaris

    Not yet reported Cairo University 55 participants Est. completion 2026-09-01 1 site
    Other conditions: Psoriasis Vulgaris
    View official trial listing →
  • Completed NCT NCT07519265

    Bioequivalence Study of Chiglitazar/Metformin Extended-Release Tablets

    Not yet reported Chipscreen Biosciences, Ltd. 64 participants Est. completion 2026-08-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07520110

    Metformin to Attenuate Progressive Respiratory Decline in Idiopathic Pulmonary Fibrosis

    Not yet reported University of Massachusetts, Worcester 800 participants Est. completion 2029-03-15 15 sites Stand-alone
    Other conditions: Idiopathic Pulmonary Fibrosis
    View official trial listing →
  • Completed NCT NCT07530289

    A Clinical Study of Ulonivirine (MK-8507) With Atorvastatin and Metformin in Healthy Adults (MK-8507-018)

    Not yet reported Merck Sharp & Dohme LLC 12 participants Est. completion 2026-06-03 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT07531108

    Effects of Empagliflozin-Metformin, Sitagliptin-Metformin, and Metformin on Adipokines in Type 2 Diabetes

    Not yet reported Hawler Medical University 186 participants Est. completion 2025-11-27 1 site
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07536620

    Metformin and Alveolar Cleft

    Not yet reported Fayoum University 36 participants Est. completion 2027-05-30 Stand-alone
    Other conditions: Alveolar Cleft
    View official trial listing →
  • Completed NCT NCT07541456

    Empagliflozin Versus Non-SGLT2 Oral Drugs for Blood Pressure in Type 2 Diabetes

    Not yet reported Dr. Zarmina Younes 300 participants Est. completion 2025-11-08 1 site
    Type 2 diabetes Other conditions: Hypertension
    View official trial listing →
  • Completed NCT NCT07541807

    Assessing Changes in Gadoxetate Metabolism by the Liver Using MRI

    Sheffield Teaching Hospitals NHS Foundation Trust 12 participants Est. completion 2025-02-28 2 sites
    Other conditions: Liver Dysfunction
    View official trial listing →
  • Completed NCT NCT07567781

    A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.

    Not yet reported AbbVie 12 participants Est. completion 2026-07-21 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Enrolling by invitation NCT NCT07568574

    Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes

    Not yet reported Enhanced Emirates Limited 60 participants Est. completion 2033-03-01 1 site Stand-alone
    Other conditions: Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes
    View official trial listing →
  • Completed NCT NCT07570082

    Drug-Drug Interaction Study of Atumelnant in Healthy Participants

    Not yet reported Crinetics Pharmaceuticals Inc. 46 participants Est. completion 2026-07-30 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT07582471

    Insulin Versus Oral Hypoglycemic Agents in Gestational Diabetes Mellitus

    Not yet reported Dr Mudassar Saeed Pansota 60 participants Est. completion 2026-04-07 1 site Stand-alone
    Other conditions: Gestational Diabetes Mellitus (GDM)
    View official trial listing →
  • Completed NCT NCT07585396

    Inositol in Letrozol Resistant PCOS Women

    Not yet reported, Not yet reported Kafrelsheikh University 136 participants Est. completion 2026-07-11 1 site
    Other conditions: Polycystic Ovary Syndrome, Infertility
    View official trial listing →
  • Completed NCT NCT07586969

    Modulation of Hyperandrogenic Anovulation Through Fenugreek Seeds

    Not yet reported University of Lahore 70 participants Est. completion 2024-12-11 1 site
    Other conditions: Poly Cystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT07589075

    Sodium-Glucose Co-Transporter-2 Inhibitors as Adjuvant Therapy With Letrozole in Induction of Ovulation

    Not yet reported Beni-Suef University 500 participants Est. completion 2025-10-30 1 site Stand-alone
    Other conditions: Induction of Ovulation
    View official trial listing →
  • Not yet recruiting NCT NCT07589387

    Hypertension Treatment in Nigeria: Hypertension Diabetes Integration Study- Formative Aim 3

    Not yet reported Washington University School of Medicine 2800 participants Est. completion 2030-01-31 Stand-alone
    Other conditions: Diabete Mellitus
    View official trial listing →
  • Completed NCT NCT07591402

    Metformine as a Protective Factor of Mortality in Type 2 Diabetic Patients Admitted to the ICU for Septic Shock.

    Assistance Publique - Hôpitaux de Paris 2740 participants Est. completion 2024-12-15 1 site
    Other conditions: D012139, D003924
    View official trial listing →
  • Completed NCT NCT07603505

    Effect of NAE on Polycystic Ovarian Syndrome (PCOS)

    Not yet reported Jinnah Sindh Medical University 116 participants Est. completion 2026-06-15 1 site Stand-alone
    Other conditions: Polycystic Ovarian Syndrome (PCOS), Infertility, Metabolic Disorders
    View official trial listing →
  • Active, not recruiting NCT NCT07604779

    Enhancing PCOS Management for Better Outcomes of Intracytoplasmic Sperm Injection

    Not yet reported Beni-Suef University 150 participants Est. completion 2027-03-03 1 site Stand-alone
    Other conditions: Polycystic Ovarian Syndrome (PCOS)
    View official trial listing →
  • Completed NCT NCT07604870

    Krill Oil and Metformin in Women With PCOS and Metabolically Unhealthy Obesity

    Not yet reported Firat University 54 participants Est. completion 2024-04-30 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Obesity, Metabolic
    View official trial listing →
  • Not yet recruiting NCT NCT07622290

    Metformin Treatment for Children With Obesity-associated Asthma

    Not yet reported Prof Ibrahim Janahi 182 participants Est. completion 2028-03 1 site
    Other conditions: Obesity-associated Asthma
    View official trial listing →
  • Completed NCT NCT07627048

    Influence of Gut Microbiota on the Development of Type 2 Diabetes Mellitus and Personalization of Diabetes-lowing Therapy

    Pirogov Russian National Research Medical University 100 participants Est. completion 2022-04-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07628556

    Antidiabetic Medications and Risk of Cancer

    University of Pecs 74799 participants Est. completion 2025-12-30 1 site
    Other conditions: Cancer
    View official trial listing →
  • Not yet recruiting NCT NCT07628985

    BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes

    Not yet reported Carnot Laboratories 374 participants Est. completion 2027-10 7 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07633015

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 5 mg / 850 mg Tablets Under Fed Conditions.

    Not yet reported ADIUM 42 participants Est. completion 2025-04-29 1 site Stand-alone
    Other conditions: Bioequivalence Study in Healthy Subjects
    View official trial listing →
  • Completed NCT NCT07633028

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 850 mg Tablets Under Fed Conditions.

    Not yet reported ADIUM 42 participants Est. completion 2025-04-08 1 site Stand-alone
    Other conditions: Bioequivalence Study in Healthy Subjects
    View official trial listing →
  • Completed NCT NCT07633041

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 1000 mg Tablets Under Fed Conditions.

    Not yet reported ADIUM 42 participants Est. completion 2025-04-04 1 site Stand-alone
    Other conditions: Bioequivalence Study in Healthy Subjects
    View official trial listing →
  • Completed NCT NCT07633054

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 500 mg Tablets Under Fed Conditions.

    Not yet reported ADIUM 42 participants Est. completion 2025-11-24 1 site Stand-alone
    Other conditions: Bioequivalence Study in Healthy Subjects
    View official trial listing →
  • Not yet recruiting NCT NCT07635953

    New Triple Combination Therapy in Newly Diagnosed Type 2 Diabetes

    Not yet reported Sun Yat-sen University 296 participants Est. completion 2031-07-01 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Not yet recruiting NCT NCT07647003

    A Study to Evaluate the Effect of Two Fixed-Dose Leucine, Sildenafil and Metformin Combinations on Blood Pressure in Individuals With Hypertension

    Not yet reported NuSirt Biopharma 150 participants Est. completion 2027-07-07 Stand-alone
    Other conditions: Hypertension
    View official trial listing →
  • Active, not recruiting NCT NCT07659444

    Metformin Withdrawal In Metabolic Syndrome

    Not yet reported University of Castilla-La Mancha 21 participants Est. completion 2026-09-30 1 site Stand-alone
    Metabolic syndrome Other conditions: Glucose Intolerance
    View official trial listing →
  • Completed NCT NCT07679711

    Bioequivalence Study of Sitagliptin/Metformin Extended-Release Tablets in Healthy Subjects

    Not yet reported The Affiliated Hospital of Qingdao University 76 participants Est. completion 2023-03-22 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Not yet recruiting NCT NCT07687667

    Effects of GLP-1RAs on Fertility Outcomes in Obese Women With PCOS

    Not yet reported Peking University Third Hospital 406 participants Est. completion 2029-12 1 site
    Other conditions: Polycystic Ovary Syndrome (PCOS), Obesity, Infertility, Female
    View official trial listing →
  • Completed NCT NCT07691203

    Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCl 25 mg/5 mg/1000 mg Extended Release Tablet Versus Trijardy® XR 25 mg/5 mg/1000 mg Extended- Release Tablets

    Not yet reported Humanis Saglık Anonim Sirketi 36 participants Est. completion 2026-07-01 1 site Stand-alone
    Type 2 diabetesCardiovascular disease
    View official trial listing →
  • Completed NCT NCT07694115

    Bioequivalence Study to Compare Empagliflozin/ Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg

    Not yet reported Humanis Saglık Anonim Sirketi 40 participants Est. completion 2026-07-01 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07696585

    New Topical Treatment in Patchy Alopecia Areata

    Not yet reported Sohag University 60 participants Est. completion 2027-12-28
    Other conditions: Alopecia Areata
    View official trial listing →
  • Enrolling by invitation NCT NCT07696806

    Microneedling-Assisted Metformin, Tranexamic Acid, and Modified Kligman's Formula for Melasma

    Not yet reported Sameh Sarsik 80 participants Est. completion 2027-08-30 1 site Stand-alone
    Other conditions: Melasma (Facial Melasma)
    View official trial listing →
  • Not yet recruiting NCT NCT07699367

    Metformin and ACLR Muscle Recovery

    Not yet reported University of Utah 40 participants Est. completion 2032-10-01 1 site Stand-alone
    Other conditions: Atrophy, Inflammation, Weakness, Muscle
    View official trial listing →
  • Completed NCT NCT07702669

    Modified Huanglian Wendan Decoction for Metabolic Syndrome

    Not yet reported First Affiliated Hospital of Heilongjiang Chinese Medicine University 180 participants Est. completion 2025-08-31 1 site Stand-alone
    Metabolic syndrome
    View official trial listing →
  • Not yet recruiting NCT NCT07708610

    Preadmission GLP-1 Receptor Agonist Plus SGLT2 Inhibitor Use and Early Outcomes After Pneumonia Hospitalization in Adults With Type 2 Diabetes

    Chung Shan Medical University 71775 participants Est. completion 2026-08-31 1 site Stand-alone
    Type 2 diabetes Other conditions: Pneumonia
    View official trial listing →
  • Not yet recruiting NCT NCT07728318

    Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients

    Not yet reported Akhtar Saeed Medical and Dental College 52 participants Est. completion 2027-05-12
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07734558

    Evaluation of Neuregulin-4 (NRG4) Levels in Obese and Non-Obese Patients With Type 2 Diabetes Mellitus

    GÜLDEN ANATACA 125 participants Est. completion 2026-12-30 1 site
    Type 2 diabetes Other conditions: Insulin Resistance
    View official trial listing →
  • Completed NCT NCT07738692

    Effects of Various Types of Ultrasound Therapy in Knee Osteoarthritis

    Not yet reported Horus University 80 participants Est. completion 2026-06-30 1 site Stand-alone
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT07751549

    Systemic and Topical Metformin Versus Glycolic Acid Peel for the Treatment of Acanthosis Nigricans

    Not yet reported Tanta University 54 participants Est. completion 2026-05-25 1 site
    Other conditions: Acanthosis Nigricans
    View official trial listing →
  • Not yet recruiting NCT NCT07753252

    Phase 1 Study in Healthy Adults to See How Sevabertinib Changes Metformin Levels in the Body

    Not yet reported Bayer 40 participants Est. completion 2026-09-28 1 site Stand-alone
    Other conditions: Healthy Participants
    View official trial listing →
  • Not yet recruiting NCT NCT07753317

    Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DM

    Not yet reported Cairo University 30 participants Est. completion 2027-03-01
    Other conditions: Controlled Type 2 Diabetic Patients With Periodontitis
    View official trial listing →
  • Completed NCT NCT07759674

    Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in Jordan

    Not yet reported Jerash Private University 25 participants Est. completion 2023-12-01 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome (PCOS) Women, Insulin Resistance Syndrome
    View official trial listing →
  • Completed NCT NCT07763899

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fast Study.

    Not yet reported ADIUM 46 participants Est. completion 2025-11-30 1 site Stand-alone
    Other conditions: Bioequivalance
    View official trial listing →
  • Completed NCT NCT07763912

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fed Study.

    Not yet reported ADIUM 46 participants Est. completion 2025-12-05 1 site Stand-alone
    Other conditions: Bioequivalence
    View official trial listing →
  • Completed NCT NCT07763951

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fast Study.

    Not yet reported ADIUM 46 participants Est. completion 2025-12-14 1 site Stand-alone
    Other conditions: Bioequivalance
    View official trial listing →
  • Completed NCT NCT07763964

    Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fed Study.

    Not yet reported ADIUM 46 participants Est. completion 2025-12-19 1 site Stand-alone
    Other conditions: Bioequivalance
    View official trial listing →
  • Not yet recruiting NCT NCT07768280

    Efficacy and Safety of Hebenrun in Patients With Type 2 Diabetes

    Not yet reported Jiangxi University of Traditional Chinese Medicine 110 participants Est. completion 2028-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT07770087

    Effect of Metformin Gel on Guided Bone Regeneration Around Immediate Dental Implant at Posterior Maxillary Region

    Not yet reported Al-Azhar University 12 participants Est. completion 2025-12-15 2 sites Stand-alone
    Other conditions: Metformin Gel, Bone Healing, Guided Bone Regeneration, Crestal Bone Loss, Peri Implant Bone Loss
    View official trial listing →
  • Not yet recruiting NCT NCT07770711

    Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS

    Not yet reported Dicle University 90 participants Est. completion 2027-06 1 site Stand-alone
    Other conditions: PCOS (Polycystic Ovary Syndrome), Insulin Resistance, Obesity (BMI>30)
    View official trial listing →
  • Not yet recruiting NCT NCT07778719

    Metformin-Dapagliflozin Effects on IGF-1 in Male T2DM With MASLD

    Not yet reported The 95th Hospital of Putian,Putian, Fujian, China 84 participants Est. completion 2027-12-11 1 site Stand-alone
    Type 2 diabetesMASLD
    View official trial listing →
  • Not yet recruiting NCT NCT07779811

    Topical Metformin Versus Triple Regimen for Epidermal Melasma

    Not yet reported Combined Military Hospital, Pakistan 104 participants Est. completion 2027-01-30 1 site Stand-alone
    Other conditions: Epidermal Melasma, Facial Hyperpigmentation
    View official trial listing →
  • Completed NCT NCT07788378

    Metformin in Elderly Patients With Type 2 Diabetes and Muscle Strength, Muscle Mass, and Physical Function: Positive or Negative Correlation?

    Fudan University 290 participants Est. completion 2024-12-24 1 site
    Other conditions: Diabete Type 2, Muscle Strength, Muscle Mass, Physical Function, Metformin
    View official trial listing →
  • Completed NCT NCT07793838

    Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS

    Not yet reported Jerash Private University 400 participants Est. completion 2026-08-01 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome (PCOS) Women
    View official trial listing →
  • Not yet recruiting NCT NCT07796191

    Drug-drug Interactions Studies of VC005 Tablets in Healthy Adult Subjects

    Not yet reported Jiangsu vcare pharmaceutical technology co., LTD 84 participants Est. completion 2026-11-30 1 site Stand-alone
    Other conditions: Healthy Adult Participants
    View official trial listing →
  • Not yet recruiting NCT NCT07796477

    A Study of SYH2069 Injection in Participants With T2DM Not Controlled With Diet/Exercise Alone or Metformin

    Not yet reported CSPC Ouyi Pharmaceutical Co., Ltd. 240 participants Est. completion 2027-10-19 1 site
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07806019

    Metformin in Parkinson's Disease: Safety and Efficacy

    Not yet reported Jinnah Medical & Dental College 70 participants Est. completion 2027-02-01
    Other conditions: Parkinsons Disease (PD)
    View official trial listing →
  • Not yet recruiting NCT NCT07810998

    Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome

    Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2027-05-10
    Other conditions: Poly Cystic Ovary Syndrome
    View official trial listing →
  • Not yet recruiting NCT NCT07811011

    Efficacy of Vildagliptin Versus Metformin in Patients With Polycystic Ovary Syndrome

    Not yet reported, Not yet reported Tanta University 70 participants Est. completion 2027-03-30
    Other conditions: Poly Cystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT07811856

    Effects of Metformin and Theory-Based Education in Women With Polycystic Ovary Syndrome

    Not yet reported Jerash Private University 900 participants Est. completion 2026-08-01 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome (PCOS) Women
    View official trial listing →
  • Active, not recruiting NCT NCT07821073

    Myo-Inositol and Folic Acid for Improving Inflammation in Polycystic Ovary Syndrome

    Not yet reported Khyber Medical University Peshawar 50 participants Est. completion 2026-09-30 1 site Stand-alone
    Other conditions: Inflammation Biomarkers, Poly Cystic Ovary Syndrome, PCOS (Polycystic Ovary Syndrome)
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: Metformin, glucophage

Related On The Pen coverage

No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.