About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Metformin
- Company
- Ziauddin University
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 167 recruiting
Efficacy results: Not yet reported
167 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 1, 2026
Find a Clinical Trial Near Me
See recruiting studies for Metformin and check eligibility with the study team.
Trial details
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Recruiting NCT NCT01042379
I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
Not yet reported QuantumLeap Healthcare Collaborative 5000 participants Est. completion 2031-12 42 sitesObstructive sleep apnea Other conditions: Breast Neoplasms, Breast Cancer, Breast Tumors, TNBC - Triple-Negative Breast Cancer, HER2-positive Breast Cancer, HER2-negative Breast Cancer, Hormone Receptor Positive Tumor, Hormone Receptor Negative Tumor, Early-stage Breast Cancer, Locally Advanced Breast CancerView official trial listing → -
Recruiting NCT NCT01638676
A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients
Not yet reported, Not yet reported University of Louisville 55 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: MelanomaView official trial listing → -
Recruiting NCT NCT02647827
Acupuncture or Metformin for Insulin Resistance in Women With PCOS
Not yet reported Karolinska Institutet 303 participants Est. completion 2026-06 2 sitesOther conditions: Polycystic Ovary Syndrome, Insulin Resistance, HyperandrogenismView official trial listing → -
Recruiting NCT NCT02915198
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes
Not yet reported VA Office of Research and Development 7410 participants Est. completion 2029-09-28 40 sites Stand-aloneOther conditions: Prediabetic State, Atherosclerosis, MetforminView official trial listing → -
Recruiting NCT NCT02947503
Pregnancy Outcomes: Effects of Metformin Study (POEM Study)
Not yet reported Bethesda Diabetes Research Center 500 participants Est. completion 2043-12 4 sitesOther conditions: Gestational Diabetes, Insulin ResistanceView official trial listing → -
Recruiting NCT NCT02969798
Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)
Not yet reported The University of Texas Health Science Center at San Antonio 700 participants Est. completion 2027-07 1 siteType 2 diabetesPrediabetesView official trial listing → -
Recruiting NCT NCT03379909
Phase II Study of Oral Metformin for Intravesical Treatment of Non-muscle-invasive Bladder Cancer
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 49 participants Est. completion 2029-10-01 3 sites Stand-aloneOther conditions: Superficial Bladder Cancer, Bladder CancerView official trial listing → -
Recruiting NCT NCT03424005
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
Not yet reported, Not yet reported Hoffmann-La Roche 1132 participants Est. completion 2030-09-30 53 sites Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT03511118
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
Duke University 1600 participants Est. completion 2028-07-31 22 sitesOther conditions: Lactating Women on Select DOI, Breastfed Infants of Mothers on Select DOIView official trial listing → -
Recruiting NCT NCT03568630
Blood Markers of Early Pancreas Cancer
University of Nebraska 1250 participants Est. completion 2028-07 1 siteType 2 diabetesPrediabetes Other conditions: Pancreas Cyst, Chronic Pancreatitis, Genetic Predisposition to Disease, Inherited DiseaseView official trial listing → -
Recruiting NCT NCT03675893
RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial Cancer
Not yet reported Dana-Farber Cancer Institute 110 participants Est. completion 2031-08-01 3 sites Stand-aloneOther conditions: Endometrial CancerView official trial listing → -
Recruiting NCT NCT03925701
Clinical Study Evaluating Vildagliptin Versus Vildagliptin/Metformin on NAFLD With DM
Not yet reported Sherief Abd-Elsalam 120 participants Est. completion 2028-12 1 siteOther conditions: dmView official trial listing → -
Recruiting NCT NCT03925714
Impact of P53 and SIRT1 in Type 2 Diabetes
Not yet reported Sherief Abd-Elsalam 90 participants Est. completion 2028-12 1 siteOther conditions: DMView official trial listing → -
Recruiting NCT NCT03989778
Vitamin D and Polycystic Ovarian Syndrome (PCOS)
Not yet reported Aga Khan University 300 participants Est. completion 2025-07-13 2 sites Stand-aloneOther conditions: Infertility, Female, Infertility, Vitamin D DeficiencyView official trial listing → -
Recruiting NCT NCT04114136
Anti-PD-1 mAb Plus Metabolic Modulator in Solid Tumor Malignancies
Not yet reported Dan Zandberg 72 participants Est. completion 2032-04-30 1 site Stand-aloneObstructive sleep apnea Other conditions: Melanoma, NSCLC, Hepatocellular Carcinoma, Urothelial Cancer, Gastric Adenocarcinoma, HNSCC, Esophageal AdenocarcinomaView official trial listing → -
Recruiting NCT NCT04121468
A Phase I Double Blind Study of Metformin Acting on Endogenous Neural Progenitor Cells in Children and Young Adults With Multiple Sclerosis
Not yet reported, Not yet reported The Hospital for Sick Children 20 participants Est. completion 2027-10 1 siteOther conditions: Multiple Sclerosis (MS)View official trial listing → -
Recruiting NCT NCT04278404
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Duke University 5000 participants Est. completion 2026-12 52 sitesHeart failure Other conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down SyndromeView official trial listing → -
Recruiting NCT NCT04500678
Impact of Metformin on Immuno-virologic Parameters in HIV
Not yet reported, Not yet reported University of Hawaii 38 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: HIV/AIDSView official trial listing → -
Recruiting NCT NCT04500756
Limiting AAA With Metformin (LIMIT) Trial
Not yet reported Stanford University 314 participants Est. completion 2028-06-30 1 siteOther conditions: Abdominal Aortic AneurysmView official trial listing → -
Recruiting NCT NCT04530383
Metformin for People With CFRD on CFTR Modulator Therapy to Improve Ion Channel Function
Not yet reported University of Kansas Medical Center 30 participants Est. completion 2028-07-15 1 site Stand-aloneOther conditions: Cystic Fibrosis-related Diabetes, Cystic FibrosisView official trial listing → -
Recruiting NCT NCT04578652
Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance
Not yet reported University of Alberta 90 participants Est. completion 2026-09 1 site Stand-aloneOther conditions: Obesity, Childhood, Insulin ResistanceView official trial listing → -
Recruiting NCT NCT04581447
Extending Time Without Diabetes After Bariatric Surgery: a Trial Comparing the Metformin Addition or Not to Standard Care
Not yet reported Assistance Publique - Hôpitaux de Paris 126 participants Est. completion 2026-11 16 sites Stand-aloneOther conditions: Diabetes, Bariatric Surgery, MetforminView official trial listing → -
Recruiting NCT NCT04670666
Efficacy and Safety of Madalena Association in the Treatment of Type II Diabetes Mellitus
Not yet reported EMS 270 participants Est. completion 2027-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT04741945
Repurposing Metformin As a Leukemia-preventive Drug in CCUS and LR-MDS
Not yet reported Kirsten Grønbæk 40 participants Est. completion 2026-02 1 site Stand-aloneOther conditions: Preleukemia, Myelodysplastic Neoplasm, Cytopenia, Preleukemic AnemiaView official trial listing → -
Recruiting NCT NCT04758000
Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse
Not yet reported Istituto Ortopedico Rizzoli 67 participants Est. completion 2027-07 1 site Stand-aloneObstructive sleep apnea Other conditions: Ewing SarcomaView official trial listing → -
Recruiting NCT NCT04939935
Implementation of Metformin theraPy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD)
Not yet reported The University of Queensland 1174 participants Est. completion 2030-12 49 sites Stand-aloneOther conditions: Autosomal Dominant Polycystic Kidney DiseaseView official trial listing → -
Recruiting NCT NCT04945148
Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide
Not yet reported Hopital Foch 640 participants Est. completion 2028-05 7 sites Stand-aloneOther conditions: Glioblastoma, IDH-wildtypeView official trial listing → -
Recruiting NCT NCT05036226
COAST Therapy in Advanced Solid Tumors and Prostate Cancer
Not yet reported, Not yet reported Medical University of South Carolina 76 participants Est. completion 2028-05-21 1 site Stand-aloneOther conditions: Prostate Cancer Recurrent, Solid Tumor, AdultView official trial listing → -
Recruiting NCT NCT05041907
Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV)
Not yet reported University of Oxford 3800 participants Est. completion 2027-01 7 sites Stand-aloneOther conditions: COVID-19View official trial listing → -
Recruiting NCT NCT05065372
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
Not yet reported Kalie Tommerdahl 60 participants Est. completion 2027-07-31 2 sitesChronic kidney diseaseCardiovascular disease Other conditions: Type 1 Diabetes, Endothelial Dysfunction, Insulin SensitivityView official trial listing → -
Recruiting NCT NCT05132439
MetfOrmin BenefIts Lower Extremities With Intermittent Claudication
Not yet reported VA Office of Research and Development 200 participants Est. completion 2032-02-28 1 site Stand-aloneAlcohol use disorderView official trial listing → -
Recruiting NCT NCT05164263
Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study
Not yet reported Getz Pharma 2000 participants Est. completion 2027-08-31 6 sites Stand-aloneOther conditions: Type II Diabetes Mellitus, Efficacy, Self, Safety IssuesView official trial listing → -
Recruiting NCT NCT05205317
Comparison of the Therapeutic Effects of VR and VR + Metformin in the Treatment of Cesarean Section Scar Defect
Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 100 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: DefectView official trial listing → -
Recruiting NCT NCT05230758
Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain Tumour
Not yet reported Donald Mabbott 140 participants Est. completion 2027-11-30 20 sites Stand-aloneOther conditions: Medulloblastoma, Childhood, Cognitive ImpairmentView official trial listing → -
Recruiting NCT NCT05243654
Efficacy and Tolerability of Adjunct Metformin for Multibacillary Leprosy
Not yet reported Oxford University Clinical Research Unit Indonesia 166 participants Est. completion 2026-09-30 6 sites Stand-aloneOther conditions: Leprosy, Leprosy, Multibacillary, Neglected Tropical DiseasesView official trial listing → -
Recruiting NCT NCT05316935
GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients
Not yet reported, Not yet reported Xiaojun Chen 80 participants Est. completion 2028-03-30 2 sites Stand-aloneOther conditions: Endometrial Neoplasms, Atypical Endometrial Hyperplasia, Progesterone ResistanceView official trial listing → -
Recruiting NCT NCT05345327
SGLT2 Inhibitors As First Line Therapy to Prevent Renal Decline in Type 2 Diabetes
Not yet reported The George Institute 994 participants Est. completion 2026-06-30 8 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT05414409
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
Not yet reported Heba M. Ismail 114 participants Est. completion 2027-03-01 1 site Stand-aloneOther conditions: Type 1 Diabetes, ObesityView official trial listing → -
Recruiting NCT NCT05426044
Metformin as a Neuroprotective Therapy for Glaucoma
Not yet reported Christopher Kai Shun Leung 125 participants Est. completion 2027-12-31 1 siteOther conditions: GlaucomaView official trial listing → -
Recruiting NCT NCT05469659
Effect of Tofogliflozin on UACR Compared to Metformin Hydrochloride in Diabetic Kidney Disease (TRUTH-DKD)
Not yet reported Shinshu University 120 participants Est. completion 2026-10-30 1 siteType 2 diabetes Other conditions: Metformin, SGLT2-InhibitorsView official trial listing → -
Recruiting NCT NCT05515978
Pragmatic Trial of Metformin for Glucose Intolerance or Increased BMI in Prostate Cancer Patients
Not yet reported University of Colorado, Denver 100 participants Est. completion 2036-11-06 4 sitesOther conditions: Prostate CancerView official trial listing → -
Recruiting NCT NCT05532813
Evaluation of the Efficacy and Safety of Metformin in the Myotonic Dystrophy Type 1 (Steinert's Disease)
Not yet reported Assistance Publique - Hôpitaux de Paris 142 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Steinert's Disease, Myotonic Dystrophy 1, MetforminView official trial listing → -
Recruiting NCT NCT05574387
Metformin as Added on Therapy in Patients With Ulcerative Colitis
Not yet reported Tanta University 46 participants Est. completion 2027-04 1 siteOther conditions: Inflammatory Bowel DiseasesView official trial listing → -
Recruiting NCT NCT05660083
Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)
Not yet reported The Methodist Hospital Research Institute 36 participants Est. completion 2028-12-02 3 sites Stand-aloneOther conditions: HER2-negative Breast Cancer, Metastatic Breast Cancer, Metaplastic Breast Carcinoma, TNBC - Triple-Negative Breast CancerView official trial listing → -
Recruiting NCT NCT05727761
Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia
Not yet reported University of Minnesota 36 participants Est. completion 2027-07-30 2 sites Stand-aloneOther conditions: Oral LeukoplakiaView official trial listing → -
Recruiting NCT NCT05744479
Metformin for Antipsychotic-induced Weight Gain in Adults With Intellectual Disability
Not yet reported Centre for Addiction and Mental Health 100 participants Est. completion 2027-03-01 1 site Stand-aloneOther conditions: Intellectual Disability, Developmental Disability, ObesityView official trial listing → -
Recruiting NCT NCT05768139
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Not yet reported, Not yet reported Eli Lilly and Company 880 participants Est. completion 2030-07 65 sites Stand-aloneOther conditions: Breast Cancer, Solid Tumors, AdultView official trial listing → -
Recruiting NCT NCT05819853
Role of Semaglutide in Restoring Ovulation in Youth and Adults With Polycystic Ovary Syndrome
Not yet reported University of Colorado, Denver 80 participants Est. completion 2028-06-30 1 site Added to GLP-1Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, ObeseView official trial listing → -
Recruiting NCT NCT05900466
Metformin for Fibromyalgia Symptoms (INFORM Trial)
Not yet reported University of Utah 72 participants Est. completion 2027-03-31 1 siteOther conditions: Fibromyalgia SyndromeView official trial listing → -
Recruiting NCT NCT05917587
Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes
Not yet reported Anna Stanhewicz, PhD 30 participants Est. completion 2028-06-30 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Recruiting NCT NCT05929495
Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma
Not yet reported University of Milano Bicocca 25 participants Est. completion 2026-01-01 1 site Stand-aloneOther conditions: Glioblastoma, IDH-wildtype, Metformin, MalignanciesView official trial listing → -
Recruiting NCT NCT06030622
Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer
Not yet reported, Not yet reported State University of New York - Downstate Medical Center 25 participants Est. completion 2028-12-30 1 site Stand-aloneOther conditions: Pancreatic Cancer MetastaticView official trial listing → -
Recruiting NCT NCT06033131
PI4 - A Trial Assessing Metformin to Prolong Gestation in Preterm Preeclampsia
Not yet reported Lina Bergman 294 participants Est. completion 2029-12-31 18 sitesOther conditions: PreeclampsiaView official trial listing → -
Recruiting NCT NCT06044025
A Feasibility Study Evaluating a Role for Maintenance Therapy in Patients With Biochemically Progressive Castration Sensitive Prostate Cancer on Intermittent Androgen Deprivation Therapy
Not yet reported University of Arkansas 34 participants Est. completion 2028-10 1 site Stand-aloneOther conditions: Castration Sensitive Prostate CancerView official trial listing → -
Recruiting NCT NCT06045351
Efficacy of Injectable Vitamin D Supplementation in Females With Polycystic Ovary Syndrome
Not yet reported Aga Khan University 142 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Anovulatory InfertilityView official trial listing → -
Recruiting NCT NCT06064669
Effect of Metformin on Healthy Live Birth in Women With Prediabetes
Not yet reported Shandong University 988 participants Est. completion 2027-12-31 1 site Stand-alonePrediabetes Other conditions: Metformin, In-Vitro FertilizationView official trial listing → -
Recruiting NCT NCT06090227
AMPK-activation by Metformin in FSGS: AMP-FSGS
Not yet reported, Not yet reported Yale University 30 participants Est. completion 2027-11 2 sites Stand-aloneOther conditions: Focal Segmental GlomerulosclerosisView official trial listing → -
Recruiting NCT NCT06096259
Preventing Injured Knees From osteoArthritis: Severity Outcomes
Not yet reported Brigham and Women's Hospital 512 participants Est. completion 2029-12 9 sites Stand-aloneOsteoarthritis Other conditions: ACL TearView official trial listing → -
Recruiting NCT NCT06120881
Precision Dosing of Metformin in Youth With T2D
Not yet reported University of California, San Francisco 20 participants Est. completion 2026-12-31 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT06142656
Efficacy of Vildagliptin Versus Metformin in Poly Cystic Ovary Syndrome
Not yet reported, Not yet reported October 6 University 60 participants Est. completion 2026-02-01 1 siteOther conditions: Poly Cystic Ovary SyndromeView official trial listing → -
Recruiting NCT NCT06185179
Metformin and Muscle Recovery
Not yet reported University of Utah 50 participants Est. completion 2030-05-31 1 site Stand-aloneOther conditions: Muscle Atrophy or WeaknessView official trial listing → -
Recruiting NCT NCT06231758
Metformin Safety and Efficacy in Osteoarthritis.
Not yet reported Mostafa Bahaa 70 participants Est. completion 2027-11-20 1 siteOther conditions: Osteo Arthritis KneeView official trial listing → -
Recruiting NCT NCT06246799
Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes
Not yet reported The University of Texas Health Science Center at San Antonio 256 participants Est. completion 2029-06-30 2 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT06273072
Metformin IN Asthma for Overweight and Obese Individuals (MINA)
Not yet reported Johns Hopkins University 100 participants Est. completion 2028-12-31 2 sitesOther conditions: Asthma, Asthma Chronic, Overweight and ObesityView official trial listing → -
Recruiting NCT NCT06318442
The GAPSID Study - How GLP-1 Analogues Prevent Steroid-Induced Diabetes
Not yet reported Imperial College London 60 participants Est. completion 2027-06-01 1 siteOther conditions: Steroid-Induced Diabetes, Steroid Induced HyperglycemiaView official trial listing → -
Recruiting NCT NCT06319560
Hydroxychloroquine in Type 2 Diabetes During Pregnancy
Not yet reported National University of Malaysia 56 participants Est. completion 2027-01-01 1 siteType 2 diabetes Other conditions: Diabetes in PregnancyView official trial listing → -
Recruiting NCT NCT06367283
Metformin Treatment of Patients with Hand Osteoarthritis
Not yet reported Marius Henriksen 150 participants Est. completion 2026-04 1 site Stand-aloneOsteoarthritisView official trial listing → -
Recruiting NCT NCT06377696
Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy
Not yet reported Mayo Clinic 100 participants Est. completion 2027-05-01 1 site Stand-aloneOther conditions: Malignant Brain NeoplasmView official trial listing → -
Recruiting NCT NCT06399835
Enavogliflozin vs. Pioglitazone on Glucose and Atherosclerosis
Not yet reported Seoul National University Bundang Hospital 120 participants Est. completion 2027-12-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06424860
Fish Oil, Metformin and Heart Health in PCOS
Not yet reported University of Alberta 146 participants Est. completion 2027-12-30 3 sites Stand-aloneCardiovascular disease Other conditions: PCOS, Atherosclerotic Plaque, Cardiac HypertrophyView official trial listing → -
Recruiting NCT NCT06445946
DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes
Not yet reported Ohio State University 1572 participants Est. completion 2030-12 24 sites Stand-aloneOther conditions: Gestational Diabetes Mellitus, Pregnancy, High RiskView official trial listing → -
Recruiting NCT NCT06449833
Effect of Henagliflozein on Hepatic Fat Content in Patients With T2DM and NAFLD
Not yet reported Zhujiang Hospital 100 participants Est. completion 2026-11 1 site Stand-aloneType 2 diabetesMASLDView official trial listing → -
Recruiting NCT NCT06459310
Pilot Study on Evaluating the Geroprotective Effect of Metformin
Not yet reported Xuanwu Hospital, Beijing 130 participants Est. completion 2028-07-31 1 site Stand-aloneOther conditions: Metformin, AgingView official trial listing → -
Recruiting NCT NCT06463743
Metformin as an add-on or Monotherapy in Treatment of Aging People With Multiple Sclerosis (MS)
Not yet reported State University of New York at Buffalo 30 participants Est. completion 2027-06-01 1 site Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Recruiting NCT NCT06528405
The Efficacy and Safety of Sodium-glucose Cotransporter 2 Inhibitors in Patients With Acute Kidney Disease
Not yet reported National Taiwan University Hospital 264 participants Est. completion 2027-12 1 siteOther conditions: Acute Kidney InjuryView official trial listing → -
Recruiting NCT NCT06537843
Safety and Efficacy of Venetoclax, Cytarabine and Metformin (VenCM) for Relapsed-Refractory and Induction-Ineligible Acute Myeloid Leukemia
Not yet reported Hospital Municipal São José 100 participants Est. completion 2028-07-01 5 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06591169
Lifestyle Changes in PCOS with OSA and NAFLD
Not yet reported Cairo University 40 participants Est. completion 2024-12-15 2 sites Stand-aloneMASLDObstructive sleep apnea Other conditions: PCOSView official trial listing → -
Recruiting NCT NCT06613854
Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in Individuals With Type 2 Diabetes
Not yet reported University Medical Centre Ljubljana 90 participants Est. completion 2027-12 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06627322
A Registry-based Randomized Controlled Trial in Type 2 Diabetes With Cardiovascular Risk Factors (REMATCH)
Not yet reported Kyu Chang Won 5950 participants Est. completion 2029-09-30 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT06661174
A Cohort Study on the Efficacy of Bariatric Surgery for Rapidly Progressing Diabetic Nephropathy
China-Japan Friendship Hospital 100 participants Est. completion 2025-10-30 1 siteChronic kidney disease Other conditions: Bariatric SurgeriesView official trial listing → -
Recruiting NCT NCT06682130
Glofitamab Bridging ASCT for Patients With Relapsed or Refractory DLBCL
Not yet reported The First Affiliated Hospital of Soochow University 40 participants Est. completion 2029-11-10 1 site Stand-aloneOther conditions: Diffuse Large B-cell Lymphoma(DLBCL)View official trial listing → -
Recruiting NCT NCT06686043
HPV Vaccine, Imiquimod, and Metformin Combination Trial
Not yet reported Baylor College of Medicine 85 participants Est. completion 2028-08-23 2 sites Stand-aloneOther conditions: Cervical Carcinoma, Vaginal Carcinoma, Vulvar Carcinoma, HPV (Human Papillomavirus)-Associated CarcinomaView official trial listing → -
Recruiting NCT NCT06687876
Metformin as a Metabolic Intervention in Oesophageal Adenocarcinomas to Improve Response to Neoadjuvant Chemoradiotherapy
Not yet reported Amsterdam UMC, location VUmc 14 participants Est. completion 2030-12 2 sites Stand-aloneOther conditions: Oesophageal Adenocarcinoma, Tumor MicroenvironmentView official trial listing → -
Recruiting NCT NCT06693934
Jockey Club Precision Prevention Programme on Young Onset Diabetes
Not yet reported Juliana CN Chan 9000 participants Est. completion 2028-05 1 siteOther conditions: Diabetes, Pre Diabetes, Hypertension, Dyslipidemia, ObesityView official trial listing → -
Recruiting NCT NCT06707012
Efficacy of Metformin as an Adjunct to Standard Antidepressant Therapy in Treating Depression Among Obese Patients
Not yet reported Fazaia Ruth Pfau Medical College 140 participants Est. completion 2026-12 2 sites Stand-aloneOther conditions: DepressionView official trial listing → -
Recruiting NCT NCT06716216
A Study of BGM0504 in Participants with Type 2 Diabetes
Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 537 participants Est. completion 2026-11-14 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06742710
Liraglutide Treatment in Obese Infertile PCOS Women
Not yet reported Peking University Third Hospital 890 participants Est. completion 2029-12-31 3 sites Added to GLP-1Other conditions: PCOS, Obesity, InfertilityView official trial listing → -
Recruiting NCT NCT06763328
Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy
Not yet reported City of Hope Medical Center 80 participants Est. completion 2029-06-16 3 sites Stand-aloneOther conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Invasive Breast CarcinomaView official trial listing → -
Recruiting NCT NCT06781775
GDM: Insulin with or Without Metformin?
Not yet reported University of Virginia 130 participants Est. completion 2027-05-01 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Recruiting NCT NCT06806345
Hyperbaric Oxygen Therapy on Insulin Resistance in Postmenopause
Not yet reported, Not yet reported Cairo University 40 participants Est. completion 2025-04-28 1 site Stand-aloneOther conditions: Insulin Resistance SyndromeView official trial listing → -
Recruiting NCT NCT06826092
Metformin for the Treatment of mCRC Patients Undergoing FOLFIRI Plus Target Therapy
Not yet reported Kaohsiung Medical University Chung-Ho Memorial Hospital 110 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Progression-Free SurvivalView official trial listing → -
Recruiting NCT NCT06829238
Assessment of Metformin for Restoration of Immune Homeostasis in HIV+ and HIV- Individuals With a History of Injection Drug Use
Not yet reported University of Alabama at Birmingham 100 participants Est. completion 2029-11-30 1 site Stand-aloneOther conditions: Systemic Inflammation, Immune Dysregulation, Injection Drug Use, HIVView official trial listing → -
Recruiting NCT NCT06836128
The Combined Effect of N-Acetyl Cysteine and Metformin in Polycystic Ovary Syndrome Patients
Not yet reported Cairo University 102 participants Est. completion 2026-05-01 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Recruiting NCT NCT06838286
Korean Study on Safety and Effectiveness of OAD Triple Therapy in Type 2 Diabetes
Chong Kun Dang Pharmaceutical 10000 participants Est. completion 2029-12-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06845540
Oral Metformin for Treating Melasma in Latin American Women
Not yet reported, Not yet reported University of Puerto Rico 30 participants Est. completion 2025-05-30 1 site Stand-aloneOther conditions: MelasmaView official trial listing → -
Recruiting NCT NCT06846411
The EMPA-FIT Study
Not yet reported Seoul National University Bundang Hospital 46 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Diabetes, Diabetes Mellitus, Type IIView official trial listing → -
Recruiting NCT NCT06862739
Glycemic Control With Triple Pathway Approach Through Empagliflozin, Linagliptin and Metformin Combination
Not yet reported Nabiqasim Industries (Pvt) Ltd 800 participants Est. completion 2026-06-30 2 sitesOther conditions: Diabetes Mellitus, Type 2 DMView official trial listing → -
Recruiting NCT NCT06863532
Efficacy and Safety Comparison of Cofrogliptin Add-on Versus Metformin Dose-escalation in Type 2 Diabetes Patients Inadequately Controlled With SGLT-2 Inhibitors Plus Low-Dose Metformin:A Multicenter, Open-Label Trial
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 80 participants Est. completion 2026-09-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT06875193
DM Treatment to Evaluate the Efficacy and Safety of Dapagliflozin or Pioglitazone in Patients with Type 2 Diabetes
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 196 participants Est. completion 2025-12-31 1 siteOther conditions: Type2diabetesView official trial listing → -
Recruiting NCT NCT06888050
Efficacy and Safety of Henagliflozin Proline and Metformin Hydrochloride Extended-release Tablets (Ⅰ) Versus Metformin Tablets in Patients With New-onset Type 2 Diabetes: a Multicenter, Randomized Controlled Study
Not yet reported Zhejiang Provincial People's Hospital 268 participants Est. completion 2026-12-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT06889454
Cardiovascular and Endothelial Markers During OGTT Before and at Six and Twelve Months Post-treatment in Women With PCOS
Attikon Hospital 120 participants Est. completion 2026-02-01 1 siteMetabolic syndrome Other conditions: PCOS, Hyperinsulinism, HyperandrogenismView official trial listing → -
Recruiting NCT NCT06896981
Semaglutide in Women With Polycystic Ovary Syndrome and Obesity
Not yet reported, Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 30 participants Est. completion 2025-12-31 1 site Added to GLP-1Other conditions: Polycystic Ovary Syndrome (PCOS) Women, ObesityView official trial listing → -
Recruiting NCT NCT06924658
Metformin in Safety and Efficacy in Gouty Patients
Not yet reported Mostafa Bahaa 70 participants Est. completion 2027-11-20 1 siteOther conditions: GoutView official trial listing → -
Recruiting NCT NCT06937294
Metformin in Post Chronic Pancreatitis Diabetes Mellitus
Not yet reported Changhai Hospital 58 participants Est. completion 2026-01-31 1 site Stand-aloneOther conditions: Chronic PancreatitisView official trial listing → -
Recruiting NCT NCT06948825
Effectiveness Study of a Lifestyle Intervention Versus Metformin in Mothers With Recent Gestational Diabetes
Not yet reported George Washington University 60 participants Est. completion 2026-11 1 siteOther conditions: Weight Loss, Gestational Diabetes Mellitus in Pregnancy, Postpartum CareView official trial listing → -
Recruiting NCT NCT06972732
A Phase IV Clinical Trial to Compare the Efficacy and Safety of Metformin+Sodium-Glucose Cotransporter 2 Inhibitor(SGLT2-i)+Thiazolidinedione (TZD) in Patients With Type 2 Diabetes
Not yet reported Boryung Pharmaceutical Co., Ltd 204 participants Est. completion 2026-10-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT06975111
Focusing on the Menopausal Transition to Improve Mid-Life Women's Health
Not yet reported, Not yet reported University of Colorado, Denver 200 participants Est. completion 2030-10-01 3 sitesOther conditions: Menopause, Menopause Hot Flashes, Menopause Related Conditions, CardiovascularView official trial listing → -
Recruiting NCT NCT07001878
Cannabis Potency Effects on Brain White Matter in Early Phase Psychosis
Not yet reported Nova Scotia Health Authority 24 participants Est. completion 2026-12-01 2 sites Stand-aloneOther conditions: Psychosis, Cannabis UseView official trial listing → -
Recruiting NCT NCT07019012
Cofrogliptin Once Every 2 Weeks as Add-on Therapy to Metformin and Dapagliflozin Versus Daily Linagliptin in Patients With Type 2 Diabetes.
Not yet reported Huazhong University of Science and Technology 170 participants Est. completion 2026-12-30 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07045142
Metformin Alleviates Abnormal Glucose Metabolism Induced by Statins in Schizophrenia Patients
Not yet reported Central South University 400 participants Est. completion 2028-06-01 8 sitesOther conditions: SchizophreniaView official trial listing → -
Recruiting NCT NCT07064486
A Study of BGM0504 in Participants With Type 2 Diabetes in Indonesia
Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 477 participants Est. completion 2026-07-31 4 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT07065591
Anti-Diabetic Drug, Exercise and Healthy Diet for Knee Osteoarthritis With Overweight/Obesity
Not yet reported The University of Hong Kong 100 participants Est. completion 2028-07-17 1 site Stand-aloneOsteoarthritisView official trial listing → -
Recruiting NCT NCT07072221
Bendamustine Combined With Chidamide and Lenalidomide for Relapsed and Refractory PTCL Patients
Not yet reported The First Affiliated Hospital of Soochow University 40 participants Est. completion 2029-11-01 1 site Stand-aloneOther conditions: Peripheral T-cell LymphomaView official trial listing → -
Recruiting NCT NCT07074379
Endotherapy and/or Extracorporeal Shockwave Lithotripsy for Painless Chronic Pancreatitis
Not yet reported Changhai Hospital 126 participants Est. completion 2037-07-01 1 site Stand-aloneOther conditions: Painless Chronic PancreatitisView official trial listing → -
Recruiting NCT NCT07082114
A Phase 3 Study to Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 800 participants Est. completion 2027-05-17 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07083388
A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fasting)
Not yet reported Boryung Pharmaceutical Co., Ltd 52 participants Est. completion 2026-07-03 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Recruiting NCT NCT07083401
A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fed)
Not yet reported Boryung Pharmaceutical Co., Ltd 40 participants Est. completion 2026-07-05 1 site Stand-aloneOther conditions: Diabete MellitusView official trial listing → -
Recruiting NCT NCT07092618
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation
Not yet reported, Not yet reported AgelessRx 150 participants Est. completion 2025-08 1 site Stand-aloneOther conditions: Longevity, GLP-1, Geroscience, AgingView official trial listing → -
Recruiting NCT NCT07093476
Efficacy and Safety of Add-On Therapy With Empagliflozin in Patients With Type 2 Diabetes on a Background of Alogliptin and Metformin
Not yet reported Celltrion 171 participants Est. completion 2027-04 1 siteType 2 diabetes Other conditions: Diabete Type 2, DMView official trial listing → -
Recruiting NCT NCT07098299
Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies
Not yet reported Barbara Ann Karmanos Cancer Institute 60 participants Est. completion 2028-07-07 10 sites Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Recruiting NCT NCT07108075
Acute Portal Pressure Reduction by Metformin and Carvedilol Compared to Carvedilol Alone in Cirrhosis.
Not yet reported Institute of Liver and Biliary Sciences, India 72 participants Est. completion 2025-10-30 1 site Stand-aloneOther conditions: Liver CirrhosisView official trial listing → -
Recruiting NCT NCT07109700
A Study of HDM1005 in Participants With T2DM Not Controlled With Diet/Exercise or Metformin
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 216 participants Est. completion 2026-02-28 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07120971
Metformin for Premature Infants With Bronchopulmonary Dysplasia
Not yet reported Medical College of Wisconsin 40 participants Est. completion 2030-09-01 1 site Stand-aloneOther conditions: Bronchopulmonary Dysplasia (BPD)View official trial listing → -
Recruiting NCT NCT07129473
Hyperemesis Gravidarum Risk Reduction With Metformin
Not yet reported, Not yet reported University of Southern California 224 participants Est. completion 2031-03 2 sites Stand-aloneOther conditions: Hyperemesis GravidarumView official trial listing → -
Recruiting NCT NCT07131384
Interaction Between Inorganic Nitrate Supplementation and Metformin in Individuals With Prediabetes
Not yet reported University of Virginia 24 participants Est. completion 2027-06-30 1 site Stand-alonePrediabetes Other conditions: Males, Females, Sedentary, MetforminView official trial listing → -
Recruiting NCT NCT07141342
Fast In-Bed Tracking (FIT) System Lifestyle Intervention is a Clinical Trial of a Bed Scale Device. Overweight Wheelchair Users Will Complete a Weight Loss Program, Half Get Scales at Baseline, Half at Month 6 Those Who Receive the Bed Scales at Baseline Are Expected to Have Increased Weight Loss
Not yet reported Jonathan Pearlman 20 participants Est. completion 2027-07-31 1 site Stand-aloneOther conditions: Disability Physical, Wheelchair, Obesity; OverweightView official trial listing → -
Recruiting NCT NCT07182526
Effects of Adding Quercetin or Alpha Lipoic Acid to Usual Care on Symptoms and Blood Markers in Iraqi Women With Polycystic Ovary Syndrome
Not yet reported Al-Mustansiriyah University 150 participants Est. completion 2026-05-01 1 site Stand-aloneOther conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral OvariesView official trial listing → -
Recruiting NCT NCT07188740
Metformin Inhibits DNMT3A Clonal Hematopoiesis in Acute Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 32 participants Est. completion 2029-08-30 1 site Stand-aloneOther conditions: DNMT3A Gene MutationView official trial listing → -
Recruiting NCT NCT07193069
Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning
Centre Hospitalier de Saint-Denis 50 participants Est. completion 2026-04-11 1 siteOther conditions: Drug Overdose, Metformin, Dapagliflozin, Lactic Acidosis, Diabetic Ketoacidosis, Intensive Care UnitsView official trial listing → -
Recruiting NCT NCT07226453
Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma
Not yet reported University of California, San Francisco 30 participants Est. completion 2030-03-31 10 sites Stand-aloneOther conditions: Posterior Fossa Ependymal TumorView official trial listing → -
Recruiting NCT NCT07229651
Metformin in Parkinson Disease
Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2027-09-20 1 siteOther conditions: Parkinson DiseaseView official trial listing → -
Recruiting NCT NCT07244003
Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 430 participants Est. completion 2028-06-30 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Recruiting NCT NCT07244575
Association Between Preoperative Metformin Exposure and Postoperative Nausea and Vomiting in Patients Undergoing General Anesthesia
Sixth Affiliated Hospital, Sun Yat-sen University 909 participants Est. completion 2033-12-31 1 siteOther conditions: Postoperative Nausea and VomitingView official trial listing → -
Recruiting NCT NCT07254572
Anti-atherosclerotic Efficacy of Selected Antidiabetic Drugs in Patients With Coronary Artery Disease and Pre-diabetes
Not yet reported National Institute of Cardiology, Warsaw, Poland 300 participants Est. completion 2029-08-01 1 siteCardiovascular diseasePrediabetesView official trial listing → -
Recruiting NCT NCT07289399
Is There a Benefit From Addition of Treadmill Walking to Diet Restriction in Psoriasis Women With PCOS?
Not yet reported Cairo University 40 participants Est. completion 2026-05-15 1 site Stand-aloneOther conditions: Psoriasis, Polycystic Ovary SyndromeView official trial listing → -
Recruiting NCT NCT07291297
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Not yet reported Wake Forest University Health Sciences 50 participants Est. completion 2033-10 2 sitesOther conditions: Sarcoma Metastatic, Sarcoma, Soft TissueView official trial listing → -
Recruiting NCT NCT07293325
Semaglutide and Tirzepatide for Genetic Aging Delay in Adults With Obesity
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 66 participants Est. completion 2027-06-02 1 siteOther conditions: Adults With Simple ObesityView official trial listing → -
Recruiting NCT NCT07297290
Effect of Metformin Use on Weight Loss in Obese, Non-diabetic People (MOWRI)
Not yet reported University Of Nigeria Teaching Hospital 220 participants Est. completion 2027-09-30 2 sites Stand-aloneOther conditions: Obesity and Cardiovascular Risk, Insulin Resistance, Obesity (Body Mass Index >30 kg/m2)View official trial listing → -
Recruiting NCT NCT07300293
Lactic Acidosis and Prior Metformin Treatment
University Hospital, Strasbourg, France 100 participants Est. completion 2026-05 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07309094
Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD
Cardenal Herrera University 250 participants Est. completion 2028-12-31 1 siteChronic kidney diseaseType 2 diabetes Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT07331389
A Drug-Drug Interaction Study of HDM1002 and Metformin, Empagliflozin, Midazolam, Valsartan, and Warfarin
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 111 participants Est. completion 2026-06-13 1 site Stand-aloneOther conditions: Overweight Subject, Healthy SubjectsView official trial listing → -
Recruiting NCT NCT07339722
A Study of LY4515100 in Healthy Participants
Not yet reported Eli Lilly and Company 123 participants Est. completion 2027-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Recruiting NCT NCT07366944
PCOS and Problem of Eye Dryness: Is There a Benefit From Lifetyle Changes
Not yet reported Cairo University 40 participants Est. completion 2026-06-05 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Dry Eye, ObesityView official trial listing → -
Recruiting NCT NCT07372625
A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
Not yet reported PMV Pharmaceuticals, Inc 14 participants Est. completion 2028-01 5 sites Stand-aloneOther conditions: TP53 Y220C Mutation, Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT07374328
Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Second Affiliated Hospital of Guangzhou Medical University 240 participants Est. completion 2026-08-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07379333
A Study to Evaluate Efficacy and Safety of HM11260C in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
Not yet reported Hanmi Pharmaceutical Company Limited 118 participants Est. completion 2028-01 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07387900
Evaluation of the Chemo-preventive Effect of Combined Topical and Systemic Metformin on Oral Leukoplakia
Not yet reported Cairo University 34 participants Est. completion 2027-10 1 site Stand-aloneOther conditions: Oral LeukoplakiaView official trial listing → -
Recruiting NCT NCT07395960
The Efficacy and Safety of Metformin Intervention in Elderly Overweight or Obesity With Mild Cognitive Impairment
Not yet reported, Not yet reported Fudan University 54 participants Est. completion 2026-09-30 1 site Stand-aloneOther conditions: Mild Cognitive Impairment, Overweight or Obesity, ElderlyView official trial listing → -
Recruiting NCT NCT07442006
Glycemic Variability of Combination Therapies in T2DM
Not yet reported JW Pharmaceutical 178 participants Est. completion 2027-03-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07446400
A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together
Not yet reported Otsuka Pharmaceutical Development & Commercialization, Inc. 48 participants Est. completion 2026-11-07 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Recruiting NCT NCT07446985
Is There a Benefit From Addition of Physical Exercise to Diet Restriction/Limitation in PCOS Women With Asthma?
Not yet reported Cairo University 40 participants Est. completion 2026-07-15 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, AsthmaView official trial listing → -
Recruiting NCT NCT07497568
Effect of Local Application of 1% Metformin Gel on Implant Stability and Peri-implant Bone Density: A Randomized Controlled Study
Not yet reported University of Baghdad 34 participants Est. completion 2027-06-01 1 site Stand-aloneOther conditions: Dental Implant, StabilityView official trial listing → -
Recruiting NCT NCT07550816
Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants
Not yet reported Beijing QL Biopharmaceutical Co.,Ltd 60 participants Est. completion 2027-03-26 1 site Stand-aloneOther conditions: Overweight,ObesityView official trial listing → -
Recruiting NCT NCT07588932
Relying on Pharmacotherapy to Improve Motor Gains in Chronic Stroke Survivors
Not yet reported Spaulding Rehabilitation Hospital 50 participants Est. completion 2028-12-31 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT07591246
Efficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid Hypofunction
Not yet reported Cairo University 40 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Non-Alcoholic Fatty Pancreatic Disease, Subclinical hypothyroïdismView official trial listing → -
Recruiting NCT NCT07630779
Efficacy of Alpha Lipoic Acid Combined With Myo-Inositol in Non-Diabetic PCOS Patients
Not yet reported Beni-Suef University 180 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Poly Cystic Ovary SyndromeView official trial listing → -
Recruiting NCT NCT07645001
Therapeutic Synergy of Probiotic Augmented Conventional Antidiabetic Pharmacotherapy in Gestational Diabetes Mellitus
Not yet reported Riphah International University 200 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Gestational DiabetesView official trial listing → -
Recruiting NCT NCT07653477
Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Metformin ± Sulfonylurea/SGLT2 Inhibitor Therapy (UNIGUIDE-2)
Not yet reported The United Bio-Technology (Hengqin) Co., Ltd. 956 participants Est. completion 2028-02-29 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07654179
Metformin as Adjunct Therapy in Depression-obesity Comorbidity: Clinical and Genetic Evaluation
Not yet reported Riphah International University 200 participants Est. completion 2027-06-11 2 sites Stand-aloneOther conditions: Depression, Depressive Disorder, Overweight or Obesity, Depressive SymptomsView official trial listing → -
Recruiting NCT NCT07693452
Metformin in Pseudomyxoma Peritonei Secondary to Appendiceal Mucinous Neoplasms
Not yet reported University of California, Irvine 15 participants Est. completion 2029-07 1 site Stand-aloneOther conditions: Appendiceal Mucinous Neoplasm, Pseudomyxoma PeritoneiView official trial listing → -
Recruiting NCT NCT07724132
An Evaluation of Treatments for Sustained Clinical Response (18 Months) in Symptomatic Alzheimer's Disease
Not yet reported University College, London 1200 participants Est. completion 2031-03 2 sitesOther conditions: Alzheimer's Disease (AD), Mild Cognitive Impairment Due to Alzheimer's Disease, Alzheimer Disease DementiaView official trial listing → -
Recruiting NCT NCT07760883
Metformin Effects According to SLC16A11 Carrier Status
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 154 participants Est. completion 2027-12 1 siteOther conditions: Diabetes Type 2View official trial listing → -
Recruiting NCT NCT07771010
The Effect of Empagliflozin and Metformin on Oxidative Capacity and Microvascular Reactivity of Skeletal Muscle in Patients With Type 2 Diabetes Mellitus
Not yet reported University Medical Centre Ljubljana 54 participants Est. completion 2028-07-31 1 siteOther conditions: Diabetes Type 2View official trial listing → -
Recruiting NCT NCT07785934
Phase I Drug-Drug Interaction Study of UBT251 Injection in Participants With Overweight or Obesity
Not yet reported The United Bio-Technology (Hengqin) Co., Ltd. 48 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Drug Drug Interaction (DDI), Pharmacokinetics and PharmacodynamicsView official trial listing → -
Recruiting NCT NCT07802561
Comparison of Metformin Versus Glyburide for Blood Sugar Control in Women With Gestational Diabetes
Not yet reported Nishtar Medical University 92 participants Est. completion 2026-10-17 1 siteOther conditions: Gestational Diabetes Mellitus (GDM)View official trial listing → -
Recruiting NCT NCT07817056
Risk-Stratified Management of Inavolisib-Induced Hyperglycemia and Patient Adherence
Tianjin Medical University Cancer Institute and Hospital 100 participants Est. completion 2028-10-31 1 siteOther conditions: Breast Cancer, HyperglycemiaView official trial listing → -
Recruiting NCT NCT07817069
Effects of Nitraria Retusa Infusion on Clozapine-induced Metabolic Side Effects
Not yet reported Faculty of Medicine, Sousse 30 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Treatment Resistant Schizophrenia, Obesity & Overweight, Abdominal ObesityView official trial listing → -
Completed NCT NCT00000620
Action to Control Cardiovascular Risk in Diabetes (ACCORD)
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 10251 participants Est. completion 2012-12 7 sitesCardiovascular diseaseType 2 diabetes Other conditions: Atherosclerosis, Hypercholesterolemia, Hypertension, Diabetes Mellitus, Coronary DiseaseView official trial listing → -
Completed NCT NCT00004992
Diabetes Prevention Program
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 3234 participants Est. completion 2001-04 1 siteOther conditions: Diabetes Mellitus, Non-Insulin-Dependent, Glucose IntoleranceView official trial listing → -
Completed NCT NCT00005104
Randomized Study of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Women With Polycystic Ovary Syndrome
Not yet reported National Center for Research Resources (NCRR) 99 participants 6 sitesOther conditions: Polycystic Ovary Syndrome, HyperinsulinismView official trial listing → -
Completed NCT NCT00005654
Randomized Study of the Effect of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Obese Women With Polycystic Ovary Syndrome
Not yet reported National Center for Research Resources (NCRR) 88 participantsOther conditions: Hyperinsulinism, Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00005669
Metformin to Treat Obesity in Children With Insulin Resistance
Not yet reported Jack Yanovski, M.D. 100 participants Est. completion 2011-05 1 siteOther conditions: Hyperinsulinemia, ObesityView official trial listing → -
Completed NCT NCT00015626
A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)
Not yet reported National Center for Research Resources (NCRR) 300 participants 1 siteOther conditions: Insulin Resistance, Diabetes MellitusView official trial listing → -
Completed NCT NCT00015691
Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalities
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 105 participants 34 sitesOther conditions: HIV Infections, Lipodystrophy, HyperinsulinemiaView official trial listing → -
Completed NCT NCT00018616
Improving Compliance With Metformin
Not yet reported US Department of Veterans Affairs 79 participants Est. completion 2005-01 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00032487
Glycemic Control and Complications in Diabetes Mellitus Type 2 (VADT)
Not yet reported VA Office of Research and Development 1791 participants Est. completion 2008-05-30 21 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00035542
A Research Study to Determine the Safety and Efficacy of Glucovance Compared to Metformin and Glyburide in Children and Adolescents With Type 2 Diabetes.
Not yet reported Bristol-Myers Squibb Est. completion 2003-10 50 sitesOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00035568
A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes
Not yet reported Bristol-Myers Squibb Est. completion 2003-06 9 sitesOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00035984
Evaluation of the Effect on Glucose Control of AC2993 in Patients With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 734 participants Est. completion 2003-08 100 sitesOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00038727
Diabetes Prevention Program Outcomes Study
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2779 participants Est. completion 2022-04-30 1 siteOther conditions: Diabetes Mellitus, Cancer, CVDView official trial listing → -
Completed NCT NCT00039013
Evaluation of the Effect on Glucose Control of AC2993 in Patients With Type 2 Diabetes Mellitus Treated With Metformin
Not yet reported AstraZeneca 336 participants Est. completion 2003-06 129 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00044447
Evaluate the Role of Adding Amaryl to Non-Insulin Dependent Diabetes Mellitus Patients Unresponsive to Maximum Dose Metformin & Thiazolidinedione
Not yet reported Sanofi 170 participants Est. completion 2002-09 1 siteOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00044668
Evaluation of the Effect on Glucose Control and Safety of AC2993 in Patients With Type 2 Diabetes Treated With Metformin, Sulfonylurea, or Metformin and Sulfonylurea Combination
Not yet reported AstraZeneca 155 participants Est. completion 2005-09 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00046462
Determine Whether Glycemic Control is Different Between Lantus & a 3rd Oral Agent When Failure With Other Treatment
Not yet reported Sanofi 240 participants Est. completion 2004-12 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00067951
A Study To Evaluate The Safety And Efficacy Of An Investigational Diabetes Drug In Poorly Controlled Type II Diabetics
Not yet reported GlaxoSmithKline 190 participants Est. completion 2004-11-30 94 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00068861
Treatment of Infertility in Women With Polycystic Ovary Syndrome
Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 678 participants Est. completion 2006-02 11 sitesOther conditions: Polycystic Ovary Syndrome, Infertility, PregnancyView official trial listing → -
Completed NCT NCT00069836
Study Of AVANDAMET® With Or Without Insulin In Type II Diabetes Mellitus Patients. AVANDAMET® is a Registered Trademark of the GSK Group of Companies.
Not yet reported GlaxoSmithKline 272 participants Est. completion 2004-11 93 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00081328
Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 699 participants Est. completion 2014-02 16 sites Stand-aloneOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT00082407
Exenatide Compared With Twice-Daily Biphasic Insulin Aspart in Patients With Type 2 Diabetes Using Sulfonylurea and Metformin
Not yet reported AstraZeneca 505 participants Est. completion 2008-07 69 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00086502
Pioglitazone Add-on Study in Patients With Type 2 Diabetes Mellitus
Not yet reported Merck Sharp & Dohme LLC 353 participants Est. completion 2005-11Type 2 diabetesView official trial listing → -
Completed NCT NCT00086515
Metformin Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-020)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 701 participants Est. completion 2007-02-02 Stand-aloneOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT00094770
An Investigational Drug Study in Patients With Type 2 Diabetes Mellitus (0431-024)
Not yet reported Merck Sharp & Dohme LLC 1172 participants Est. completion 2007-05Type 2 diabetesView official trial listing → -
Completed NCT NCT00095030
Study Comparing Muraglitazar With Glimepiride in Type 2 Diabetics Who Are Not Controlled With Metformin Alone
Not yet reported Bristol-Myers Squibb 1752 participants Est. completion 2006-03 206 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00097279
Comparison of Biphasic Insulin Aspart 70/30 With Anti-Diabetic Drugs in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 230 participants Est. completion 2005-08 73 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00097500
Effects of Exenatide and Insulin Glargine in Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 69 participants Est. completion 2009-12 3 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00097877
Comparison of Biphasic Insulin Aspart 70/30 Versus Insulin Glargine in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 293 participants Est. completion 2006-11 73 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00099320
Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Thiazolidinediones or Thiazolidinediones and Metformin
Not yet reported AstraZeneca 182 participants Est. completion 2005-08 51 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00099619
Comparing Exenatide and Insulin Glargine in Type 2 Diabetes Patients for Whom Insulin is the Next Appropriate Therapy
Not yet reported AstraZeneca 138 participants Est. completion 2005-08 26 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00099866
Efficacy and Safety of Vildagliptin Compared to Metformin in Drug Naive Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 570 participants Est. completion 2005-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00099892
Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 544 participants Est. completion 2005-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00102466
Vildagliptin Compared to Gliclazide in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 1007 participants Est. completion 2009-01 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00103857
MK0431 (Sitagliptin) and Metformin Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-036)
Not yet reported Merck Sharp & Dohme LLC 1208 participants Est. completion 2008-02-21 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00105066
The Effects of Metformin on Blood Vessel Structure and Function
Not yet reported National Institute on Aging (NIA) 77 participants Est. completion 2008-05 1 site Stand-aloneOther conditions: Obesity, Hypertension, Hypercholesterolemia, HyperglycemiaView official trial listing → -
Completed NCT NCT00106340
Vildagliptin Compared to Glimepiride in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 3118 participants Est. completion 2008-05-20 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00106704
Sulfonylurea Add-on Study in Patients With Type 2 Diabetes Mellitus (0431-035)
Not yet reported Merck Sharp & Dohme LLC 441 participants Est. completion 2007-01Type 2 diabetesView official trial listing → -
Completed NCT NCT00108615
Effects of Insulin Sensitizers in Subjects With Impaired Glucose Tolerance
Not yet reported US Department of Veterans Affairs 48 participants Est. completion 2007-12 1 site Stand-aloneOther conditions: Glucose Metabolism Disorders, DiabetesView official trial listing → -
Completed NCT NCT00110851
Safety and Efficacy Study of PN2034 in Type 2 Diabetes Patients on Concomitant Rosiglitazone and Metformin (or Avandamet)
Not yet reported Wellstat Therapeutics 90 participants Est. completion 2007-08 20 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00111631
A Study of DPP-IV Inhibitor in Patients With Type 2 Diabetes
Not yet reported Hoffmann-La Roche 218 participants Est. completion 2006-10 37 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00118937
Effect of Metformin in Patients With Type-1 Diabetes With Inadequate Glycaemic Control by Insulin and Diet
Not yet reported Steno Diabetes Center Copenhagen 100 participants Est. completion 2006-08Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00118950
Effect of Metformin Versus Repaglinide Treatment in Non-Obese Type 2 Diabetic Patients Uncontrolled by Diet
Not yet reported Steno Diabetes Center Copenhagen 100 participants Est. completion 2003-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00118963
Effect of Repaglinide Versus Metformin Treatment in Non-Obese Patients With Type-2-Diabetes
Not yet reported Steno Diabetes Center Copenhagen 102 participants Est. completion 2006-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00121641
Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Not yet reported AstraZeneca 1035 participants Est. completion 2010-02 134 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00121667
Study Assessing Saxagliptin Treatment In Type 2 Diabetic Subjects Who Are Not Controlled With Metformin Alone
Not yet reported AstraZeneca 1462 participants Est. completion 2010-02 152 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00121966
South Danish Diabetes Study: Evaluation of the Antidiabetic Treatment of Type 2 Diabetes Mellitus
Not yet reported Odense University Hospital 400 participants Est. completion 2007-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00123110
Insulin Resistance and Testosterone in Women
Not yet reported University of Pennsylvania 35 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Insulin Resistance, PostmenopauseView official trial listing → -
Completed NCT NCT00131664
Avandia™ + Amaryl™ or Avandamet™ Compared With Metformin (AVALANCHE™ Study)
Not yet reported Canadian Heart Research Centre 391 participants Est. completion 2008-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00133718
A 2 Year Trial of Patients With Type 2 Diabetes Focusing on Cardiovascular Diagnostics and Metabolic Control
Not yet reported Asker & Baerum Hospital 120 participants Est. completion 2012-05-29 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00134290
The Effects of Calorie Restriction With or Without Metformin on Weight and Insulin Resistance
Not yet reported University Hospital, Ghent 48 participants Est. completion 2004-05 1 siteOther conditions: Body Weight, Insulin ResistanceView official trial listing → -
Completed NCT NCT00134303
Trial Comparing Metformin Versus Placebo in Non Alcoholic Steatohepatitis (NASH) Patients Receiving Bariatric Surgery for Obesity
Not yet reported University Hospital, Ghent 65 participants Est. completion 2006-03-31 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT00135096
Insulin Glulisine Administered Pre-meal Versus Post-meal in Adult Subjects With Type 2 Diabetes Mellitus Receiving Insulin Glargine as Basal Insulin
Not yet reported Sanofi 345 participants Est. completion 2007-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00135330
An Evaluation of Exenatide and Rosiglitazone in Subjects With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 137 participants Est. completion 2008-07 19 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00138515
Extension to a Study on the Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Novartis 418 participants Est. completion 2006-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00138567
Extension to a Study on the Efficacy and Safety of Vildagliptin Compared to Metformin in Drug Naive Patients With Type 2 Diabetes
Not yet reported Novartis 530 participants Est. completion 2006-08 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00145379
The Effect of Metformin in Overweight Patients With Dysregulated Type 1 Diabetes Mellitus
Not yet reported Odense University Hospital 42 participants Est. completion 2006-06 1 site Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00147719
WelChol® With Metformin in Treating Patients With Type 2 Diabetes
Not yet reported Daiichi Sankyo 300 participants Est. completion 2006-07 48 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00147836
Evaluation of the Effects of Different Interventions on Glycemic Control in Newly-Diagnosed Type 2 Diabetic Patients
Not yet reported Sun Yat-sen University 436 participants Est. completion 2007-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00151411
Lifestyle Intervention and Metformin for Women With Polycystic Ovary Syndrome (PCOS)
Not yet reported Milton S. Hershey Medical Center 114 participants Est. completion 2008-03 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00155545
Influence of Leg Length Discrepancy on the Spinal Shape and Biomechanics in Functional and Idiopathic Scoliosis Patients
Not yet reported National Taiwan University Hospital 30 participants Est. completion 2008-09 1 siteOther conditions: Leg Length Discrepancy, ScoliosisView official trial listing → -
Completed NCT NCT00156897
Efficacy and Safety of ATL-962 in Obese Diabetics
Not yet reported Alizyme 600 participants Est. completion 2005-10 37 sitesOther conditions: Non-Insulin-Dependent Diabetes Mellitus, ObesityView official trial listing → -
Terminated NCT NCT00159211
Abdominal Adipose Tissue Distribution in Type 2 Diabetic Patients Treated During 6 Months With Pioglitazone or Insulin
Not yet reported Assistance Publique - Hôpitaux de Paris 28 participants Est. completion 2007-05 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00159575
Metformin in Assisted Reproduction-MET-AR-study
Not yet reported Norwegian University of Science and Technology 150 participants Est. completion 2010-04 2 sites Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00162240
PPAR - Combination With Metformin
Not yet reported Bristol-Myers Squibb 534 participants Est. completion 2004-05 203 sitesOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT00169624
Peripheral and Coronary Endothelial Dysfunction In Type 2diabetic Patients- Role of Metformin
Not yet reported Hospices Civils de Lyon 30 participants 1 siteOther conditions: Coronary and Peripheral Endothelial DysfunctionView official trial listing → -
Completed NCT NCT00174642
Opposing Step-by-step Insulin Reinforcement to Intensified Strategy
Not yet reported Sanofi 811 participants 18 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT00182494
Diabetes Prevention Program in Schizophrenia [DPPS]
Not yet reported Hamilton Health Sciences Corporation 200 participants Est. completion 2009-01 1 siteOther conditions: Diabetes Mellitus, SchizophreniaView official trial listing → -
Completed NCT NCT00184574
Comparison of Biphasic Insulin Aspart 70/30, 50/50, and 30/70 in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 603 participants Est. completion 2006-03 108 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00184626
Comparison of Insulin Glargine Versus Biphasic Insulin Aspart 30/70 or Biphasic Insulin Aspart 30/70 in Combination With Metformin in Subjects With Type 2 Diabetes.
Not yet reported Novo Nordisk A/S 97 participants Est. completion 2005-10-24 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00187681
Organic Cation Transporter 1 (OCT1), on Response to Metformin in Healthy Subjects
Not yet reported University of California, San Francisco 20 participants Est. completion 2008-03 1 site Stand-aloneOther conditions: Other Conditions That May Be A Focus of Clinical AttentionView official trial listing → -
Completed NCT NCT00187720
Genetic Basis for Variation in the Renal Elimination of Metformin
Not yet reported University of California, San Francisco 23 participants Est. completion 2008-04 1 site Stand-aloneOther conditions: Other Conditions That May Be A Focus of Clinical AttentionView official trial listing → -
Completed NCT NCT00187798
Impact of Genetics on Metformin Pharmacokinetics
Not yet reported University of California, San Francisco 24 participants Est. completion 2007-07 1 siteOther conditions: Other Conditions That May Be A Focus of Clinical AttentionView official trial listing → -
Completed NCT NCT00191464
Long-Term Effects of Insulin Plus Metformin Regimens on the Overall and Postprandial Glycemic Control of Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 320 participants Est. completion 2005-09 7 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00203632
Glitazones and Endothelial Function (GATE)
Not yet reported University of Calgary 40 participants Est. completion 2007-10 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT00209482
Glaser Obesity Study
Not yet reported, Not yet reported Glaser Pediatric Research Network 76 participants Est. completion 2007-11 5 sitesOther conditions: ObesityView official trial listing → -
Terminated NCT NCT00214591
GALLANT 5 Tesaglitazar Versus Metformin
Not yet reported AstraZeneca 580 participants Est. completion 2006-12 130 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00219440
A Portion-controlled Diet Will Prevent Weight Gain in Diabetics Treated With ACTOS
Not yet reported Pennington Biomedical Research Center 60 participants Est. completion 2006-12 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00231647
A Study on Efficacy and Safety of Topiramate OROS Controlled-Release in Obese, Type 2 Diabetic Subjects Managed With Diet or Metformin
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 113 participants Est. completion 2004-10Type 2 diabetes Other conditions: Obesity, Diabetes Mellitus, Adult-OnsetView official trial listing → -
Completed NCT NCT00231660
A Study of the Efficacy and Safety of Topiramate in the Treatment fo Obese, Type 2 Diabetic Patients Treated With Metformin
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 211 participants Est. completion 2002-06Type 2 diabetes Other conditions: Obesity, Diabetes Mellitus, Adult-OnsetView official trial listing → -
Completed NCT NCT00237237
Vildagliptin Compared to Pioglitazone in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Novartis 588 participants 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00240370
A Study to Evaluate Combining Metformin With Muraglitazar or Pioglitazone in Type 2 Diabetics
Not yet reported Bristol-Myers Squibb 1159 participants 85 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00241423
Effect of Exenatide on 24-Hour Blood Glucose Profile Compared With Placebo in Patients With Type 2 Diabetes
Not yet reported AstraZeneca 30 participants Est. completion 2007-06 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00241605
AVANDAMET Versus Metformin For Type 2 Diabetes Mellitus
Not yet reported GlaxoSmithKline 600 participants Est. completion 2005-12-16 91 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT00247117
Metformin in Patients With Non-Alcoholic Fatty Liver Disease (NAFLD)
Not yet reported Kaplan Medical Center 15 participants Est. completion 2005-08 1 siteOther conditions: Liver DiseasesView official trial listing → -
Terminated NCT NCT00251953
GALLANT 8 Tesaglitazar Add-on to Metformin
Not yet reported AstraZeneca 555 participants Est. completion 2006-03 107 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00263276
A Trial of BMS-512148 in Patients With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 389 participants Est. completion 2007-02 144 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00263965
ARAMIS: Actions of tesaglitazaR on fAt Metabolism and Insulin Sensitivity
Not yet reported AstraZeneca 105 participants Est. completion 2006-07 3 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT00265746
Prevention of Diabetes Mellitus Development in Women Who Had Already Experienced A Gestational Diabetes
Not yet reported Medical University of LodzType 2 diabetesView official trial listing → -
Completed NCT NCT00266253
A Study of GK Activator (2) in Patients With Type 2 Diabetes Mellitus Treated With a Stable Dose of Metformin
Not yet reported Hoffmann-La Roche 220 participants Est. completion 2007-03 47 sites Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT00268476
Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy
Not yet reported, Not yet reported Medical Research Council 11992 participants Est. completion 2030-12 120 sites Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00269061
Study In Patients With Type 2 Diabetes Who Are Taking Metformin And Sulfonylurea, Metformin And Insulin, Or Insulin
Not yet reported GlaxoSmithKline 32 participants 1 siteOther conditions: Non-Insulin-Dependent Diabetes MellitusView official trial listing → -
Completed NCT NCT00272064
ELEONOR STUDY: Insulin Glulisine in Type 2 Diabetes Mellitus.
Not yet reported Sanofi 352 participants Est. completion 2008-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00279045
Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide
Not yet reported GlaxoSmithKline 4426 participants Est. completion 2006-06-19 490 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00279240
Life Style Modifications Prevents Type 2 Diabetes in Asian Indians
Not yet reported M.V. Hospital for Diabetes Est. completion 2004-12 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00282451
Effect of Biphasic Insulin Compared to Biphasic Insulin Combined With Insulin Aspart, With or Without Metformin in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 79 participants Est. completion 2006-08 4 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT00282945
Beta Cell Function Tests Over Time In Patients With T2dm Randomized To Metformin Or Rosiglitazone
Not yet reported Pfizer 29 participants Est. completion 2007-10 2 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00283049
Insulin Glargine Injection Treatment in Place of Thiazolidinedione (TZD), Sulfonylurea, or Metformin in Triple Agent Therapy for Type 2 Diabetes Mellitus (T2DM) Adult Subjects With Unsatisfactory Control
Not yet reported Sanofi 390 participants Est. completion 2008-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00283816
Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy
Not yet reported University of Rochester 36 participants Est. completion 2008-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00286442
Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus
Not yet reported Takeda 527 participants Est. completion 2007-06 56 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00290940
Evaluation of Glucose Lowering Effect, Safety and Tolerability of CS-917
Not yet reported Daiichi Sankyo 400 participants Est. completion 2007-04 66 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00295633
A Study Assessing Saxagliptin Treatment in Type 2 Diabetic Subjects Who Are Not Controlled With TZD Therapy Alone
Not yet reported AstraZeneca 565 participants Est. completion 2008-10 133 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00299871
Dose Ranging Study of the GLP-1 Agonist AVE0010 in Metformin-Treated Subjects With Type 2 Diabetes Mellitus
Not yet reported Sanofi 542 participants Est. completion 2007-08 7 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT00303537
Metformin in Non-Alcoholic Fatty Liver Disease
Not yet reported, Not yet reported University Hospital, Aker 90 participants Est. completion 2008-06 4 sitesOther conditions: Fatty LiverView official trial listing → -
Completed NCT NCT00308373
Effects of Fats on Blood Glucose in People With and Without Type 2 Diabetes Mellitus
Not yet reported Mayo Clinic 73 participants Est. completion 2005-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00309608
Efficacy and Safety of BI 1356 BS (Linagliptin) in Combination With Metformin in Patients With type2 Diabetes
Not yet reported Boehringer Ingelheim 333 participants 48 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00313001
Effects of Biphasic Insulin Aspart 70/30 vs. Exenatide in Type 2 Diabetes Patients Not Reaching Blood Glucose Targets on Metformin and a Sulfonylurea.
Not yet reported Novo Nordisk A/S 373 participants Est. completion 2007-07 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00313313
A Study of Saxagliptin in Subjects With Type 2 Diabetes Who Have Inadequate Blood Sugar Control With Sulfonylureas
Not yet reported AstraZeneca 768 participants Est. completion 2008-09 115 sites Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00316082
Study of BMS-477118 as Monotherapy With Titration in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Not yet reported AstraZeneca 365 participants Est. completion 2008-11 74 sites Stand-aloneOther conditions: DiabetesView official trial listing → -
Status unknown NCT NCT00317928
Efficacy of Metformin in PCOS: Metabolic and Hormonal Factors
Not yet reported Aarhus University Hospital Skejby 50 participants Est. completion 2004-09Other conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00318461
To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together
Not yet reported Novo Nordisk A/S 1091 participants Est. completion 2008-11 190 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00318656
24-Hour Glycemia: Rosiglitazone Versus Glimepiride In Type 2 Diabetes
Not yet reported GlaxoSmithKline 23 participants Est. completion 2007-10Other conditions: Non-Insulin-Dependent Diabetes MellitusView official trial listing → -
Status unknown NCT NCT00319293
Efficacy of Metformin in Lean Women With Polycystic Ovary Syndrome
Not yet reported Aarhus University Hospital Skejby 20 participantsOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00324363
Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using Metformin or Sulfonylureas and Metformin
Not yet reported AstraZeneca 466 participants Est. completion 2007-04 14 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00325910
Patients With Heart Failure ANd Type 2 Diabetes Treated With Placebo Or Metformin (PHANTOM) Pilot Study
Not yet reported University of Alberta 100 participants Est. completion 2007-05 2 sitesType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT00327015
A Phase 3 Study of BMS-477118 in Combination With Metformin in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Not yet reported AstraZeneca 1306 participants Est. completion 2008-12 211 sites Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00328172
Efficacy and Safety of 3 Doses of BI1356 (Linagliptin) in Type 2 Diabetes Patients
Not yet reported Boehringer Ingelheim 302 participants 71 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00331851
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 584 participants Est. completion 2007-04 116 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT00332085
Pilot Trial of Chromium-Metformin Combination in Type 2 Diabetes
Not yet reported Bastyr University 40 participants Est. completion 2007-03 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00332488
Efficacy and Safety of Prandial Inhalation of Technosphere/Insulin in Combination With Metformin or Technosphere/Insulin Alone Versus 2 Oral Anti-Diabetic Agents in Subjects With Type 2 Diabetes
Not yet reported Mannkind Corporation 547 participants 120 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00333151
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 576 participants Est. completion 2007-08 89 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT00343395
Rosiglitazone and Metformin: Outcomes Trial in Nondiabetic Patients With Stable Coronary Syndromes (Romance) Pilot Study
Not yet reported Intermountain Health Care, Inc. 200 participants Est. completion 2008-01 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00344851
Exenatide and Metformin Therapy in Overweight Women With PCOS
Not yet reported Metabolic Center of Louisiana Research Foundation 60 participants Est. completion 2007-06 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00347100
Insulin Glargine in Type 2 Diabetic Patients
Not yet reported Sanofi 387 participants 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT00348712
Efficacy and Safety of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 301 participants Est. completion 2008-03-05 74 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00348725
Acceptability of a Fixed Combination of Fenofibrate and Metformin
Not yet reported Solvay Pharmaceuticals 69 participants 25 sitesOther conditions: Dyslipidemia/Glucose Metabolism DisorderView official trial listing → -
Completed NCT NCT00349128
Fenofibrate in Dyslipidemia and Metformin-Controlled Diabetes
Not yet reported, Not yet reported Solvay Pharmaceuticals 382 participants 51 sitesOther conditions: Dyslipidemia/Glucose Metabolism DisorderView official trial listing → -
Completed NCT NCT00350779
Sitagliptin Metformin/PPARg Agonist Combination Therapy Add-on (0431-052)
Not yet reported Merck Sharp & Dohme LLC 262 participants Est. completion 2008-06-11Type 2 diabetesView official trial listing → -
Completed NCT NCT00351884
Efficacy of Vildagliptin 100 MG as Compared to Placebo as Add-on to Metformin in Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 370 participants 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00353691
Glimepiride vs Metformin as Monotherapy in Pediatric Subjects With Type 2 Diabetes Mellitus
Not yet reported Sanofi 100 participants Est. completion 2004-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00357370
A Pilot Study of BMS-512148 in Subjects With Type 2 Diabetes
Not yet reported, Not yet reported AstraZeneca 163 participants Est. completion 2008-03 23 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00358124
Insulin Glargine v Rosiglitazone as add-on Therapy in Patients Failing Sulfonylurea and Metformin Combination Therapy
Not yet reported Sanofi 220 participants Est. completion 2002-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00359112
AVANDAMET Versus Metformin And Sulphonylurea In People With Poorly Controlled Type 2 Diabetes
Not yet reported GlaxoSmithKline 544 participants 142 sitesOther conditions: Non-Insulin-Dependent Diabetes MellitusView official trial listing → -
Completed NCT NCT00359762
Exenatide Versus Glimepiride in Patients With Type 2 Diabetes
Not yet reported AstraZeneca 1029 participants Est. completion 2011-03 114 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00360698
Insulin Glulisine in Type 2 Diabetic Patients
Not yet reported Sanofi 106 participants Est. completion 2008-08 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00361738
Dose-Ranging Study Evaluating AVE2268 in Patients With Type 2 Diabetes Not Adequately Controlled by a Metformin Treatment
Not yet reported Sanofi 317 participants Est. completion 2008-01 11 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00361868
Fenofibrate and Metformin Fixed Combination vs Rosiglitazone - FAME ROSI
Not yet reported Solvay Pharmaceuticals 88 participants Est. completion 2007-12 70 sites Stand-aloneOther conditions: Dyslipidemia, Glucose Metabolism DisorderView official trial listing → -
Completed NCT NCT00362323
Fenofibrate and Metformin Fixed Combination vs Metformin - FAME METFO
Not yet reported Solvay Pharmaceuticals 482 participants Est. completion 2009-03 70 sites Stand-aloneOther conditions: Dyslipidemia/Glucose Metabolism DisorderView official trial listing → -
Completed NCT NCT00363948
Controlled Study of MK-0431/ONO-5435 in Patients With Type 2 Diabetes Mellitus
Not yet reported Ono Pharmaceutical Co., Ltd. 188 participants 8 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00366301
The LANCET Trial: A Trial of Long-acting Insulin Injection to Reduce C-reactive Protein in Patients With Type 2 Diabetes
Not yet reported Brigham and Women's Hospital 500 participants Est. completion 2009-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00367055
Rosiglitazone-Metformin Combination Versus Metformin-Sulfonylurea Combination On Beta-Cell Function In Type 2 Diabetes
Not yet reported GlaxoSmithKline 84 participants Est. completion 2008-10Type 2 diabetesView official trial listing → -
Status unknown NCT NCT00370617
Pegylated-Interferon and Ribavirin Plus Metformin in the Treatment of Chronic HCV Infection and Insulin Resistance
Not yet reported University of Turin, Italy 200 participants Est. completion 2009-01 1 siteOther conditions: Chronic Hepatitis C, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT00371306
Comparison of Glucovance to Insulin for Diabetes During Pregnancy
Not yet reported Regional Obstetrical Consultants 200 participants Est. completion 2008-09 1 siteType 2 diabetes Other conditions: Gestational Diabetes, PregnancyView official trial listing → -
Completed NCT NCT00373178
Metabolic Effects of Treatment in Patients With Recently Diagnosed Type 2 Diabetes
Not yet reported Aristotle University Of Thessaloniki 100 participants Est. completion 2008-06 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00374907
A Study Assessing Saxagliptin Treatment in Subjects With Type 2 Diabetes Who Are Not Controlled With Diet and Exercise
Not yet reported AstraZeneca 156 participants Est. completion 2009-12 3 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00375388
The HOME Trial: Hyperinsulinaemia: the Outcome of Its Metabolic Effects, a Randomized Controlled Trial
Not yet reported Bethesda General Hospital, Hoogeveen 400 participants Est. completion 2002-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00376038
Drug Interactions From Simultaneous Administration Of Metformin And GSK189075 To Subjects With Type 2 Diabetes
Not yet reported GlaxoSmithKline 13 participants Est. completion 2006-10 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT00378729
Surgical Ovarian Drilling Versus Hormonal Treatment for Infertility Associated to PolyCystic Ovaries Syndrome (PCOS)
Not yet reported Assistance Publique - Hôpitaux de Paris 252 participants Est. completion 2011-10 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00379769
RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes
Not yet reported GlaxoSmithKline 4447 participants Est. completion 2008-12 446 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00382096
Efficacy of Fixed Combination Therapy of Vildagliptin and Metformin Compared to the Individual Monotherapy Components in Drug Naive Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 1179 participants Est. completion 2008-06-03 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00383578
Efficacy and Safety of Vildagliptin Compared to Metformin in Elderly Drug Naive Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 335 participants 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00384215
Insulin Glargine [rDNA Origin] Injection vs Pioglitazone as add-on Therapy in Patients Failing Monotherapy With Sulfonylurea or Metformin
Not yet reported Sanofi 352 participants Est. completion 2005-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00386100
A Type 2 Diabetes Study of the Longer-Term Glycemic Effect of AVANDAMET vs. Metformin
Not yet reported GlaxoSmithKline 688 participants Est. completion 2009-09 116 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00390273
Effect of Metformin on Lactate Metabolism
Not yet reported, Not yet reported Centre de Recherche en Nutrition Humaine Rhone-Alpe 20 participants Est. completion 2007-10 1 siteOther conditions: HyperlactatemiaView official trial listing → -
Completed NCT NCT00391261
An Open-label Trial of Metformin for Weight Control of Pediatric Patients on Antipsychotic Medications.
Not yet reported Cambridge Health Alliance 11 participants Est. completion 2007-10 1 siteOther conditions: Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder, Bipolar Disorder, Autism Spectrum DisordersView official trial listing → -
Completed NCT NCT00396071
Efficacy and Safety of Vildagliptin Compared to Placebo on the Incretin Effect in Patients With Type 2 Diabetes Treated With Metformin
Not yet reported Novartis Pharmaceuticals 22 participants 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00396227
Safety and Efficacy of Vildagliptin vs. Thiazolidinedione as add-on Therapy to Metformin in Patients With Type 2 Diabetes Not Controlled With Metformin Alone
Not yet reported Novartis Pharmaceuticals 2665 participants 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00396357
Efficacy/Safety of Vildagliptin and Metformin Combination Therapy in Patients With Type 2 Diabetes Not Well Controlled With Metformin Alone
Not yet reported Novartis Pharmaceuticals 914 participants 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT00396513
Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial.
Not yet reported Poznan University of Medical Sciences 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT00396851
Double Blind Randomized Trial to Compare Gurmar (Gymnema Sylvestre) With Metformin in Type 2 Diabetes
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 100 participants 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT00399204
Comparison of Cardiovascular Outcomes of Pioglitazone and Metformin in Type 2 Diabetes Patients
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh Est. completion 2012-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00399360
Lifestyle Modification and Metformin Use in the Treatment of HIV
Not yet reported Massachusetts General Hospital 50 participants Est. completion 2012-06 1 siteMetabolic syndrome Other conditions: HIV InfectionsView official trial listing → -
Completed NCT NCT00399711
Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 560 participants Est. completion 2007-11 103 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00400231
The Fenofibrate and Metformin for Atherogenic Dyslipidemia (FAMA) Study
Not yet reported University of Pennsylvania 124 participants Est. completion 2008-03 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT00401973
Assessment of Safety and Efficacy of Therapy for the Prevention of Weight Gain Associated With Olanzapine
Not yet reported Eli Lilly and Company 199 participants Est. completion 2008-09 15 sites Stand-aloneOther conditions: Schizophrenia, Schizoaffective DisordersView official trial listing → -
Completed NCT NCT00402909
Safety and Efficacy of Nateglinide in Patients With Type 2 Diabetes Already Taking Insulin Glargine, Metformin and/or Pioglitazone or Rosiglitazone
Not yet reported Novartis Pharmaceuticals 28 participants Est. completion 2007-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00413179
The Effect of Metformin Added to Clomiphene Citrate on Pregnancy Rates in Hyperandrogenic, Chronic Oligoovulatory or Anovulatory Women
Not yet reported 59th Medical Wing 56 participants Est. completion 2003-04 1 siteOther conditions: Polycystic Ovary Syndrome, Anovulation, Oligoovulation, Infertility, HyperandrogenismView official trial listing → -
Status unknown NCT NCT00414245
Metformin for the Treatment of Diabetes in Pregnancy
Not yet reported Soroka University Medical Center 200 participants 1 siteType 2 diabetes Other conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT00420511
Beta-Cell Function and Sitagliptin Trial (BEST)
Not yet reported Samuel Lunenfeld Research Institute, Mount Sinai Hospital 21 participants Est. completion 2009-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00423501
A Study of a GLP-1 Analogue in Patients With Type 2 Diabetes Treated With Metformin.
Not yet reported Hoffmann-La Roche 306 participants Est. completion 2007-11 49 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00425009
Therapeutic Effects of Berberine in Patients With Type 2 Diabetes
Not yet reported, Not yet reported Shanghai Jiao Tong University School of Medicine 70 participants Est. completion 2004-12 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00427154
Effect of Inhaled Pre-prandial Human Insulin on Blood Glucose Control in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 227 participants Est. completion 2008-03-11 103 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00428311
Effects of Metformin vs Oral Contraceptives on CV Risk Markers in PCOS
Not yet reported Hospital Universitario Ramon y Cajal 50 participants Est. completion 2006-10 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00432276
Efficacy of Alogliptin and Pioglitazone in Subjects With Type 2 Diabetes Mellitus
Not yet reported Takeda 803 participants Est. completion 2009-06 86 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00434954
Effect of Exenatide Plus Metformin vs. Insulin Aspart Plus Metformin on Glycemic Control and Hypoglycemia in Patients With Type 2 Diabetes
Not yet reported AstraZeneca 494 participants Est. completion 2009-06 39 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00437333
Metformin Suspension and Insulin Sensitivity
Not yet reported University Magna Graecia 30 participants Est. completion 2006-04 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00437554
Phase III Study for Glimepiride + Metformin Hydrochloride (Amaryl M) Slow Release (SR)
Not yet reported Handok Inc. 188 participants Est. completion 2007-07 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00441363
Efficacy and Safety of Cycloset® Compared With Placebo When Added to Metformin
Not yet reported VeroScience 66 participants Est. completion 2006-03Type 2 diabetesView official trial listing → -
Completed NCT NCT00443755
Effect of Insulin Sensitizer Therapy on Atherothrombotic and Inflammatory Profiles Associated With Insulin Resistance
Not yet reported Mayo Clinic 28 participants Est. completion 2010-08 1 siteType 2 diabetesMetabolic syndrome Other conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT00445627
Effect of Short-Term Beta-Cell Rest in Adolescents and Young Adults With Type 2 Diabetes Mellitus
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 82 participants 1 siteType 2 diabetes Other conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT00449553
Observational Study to Assess Glycosylated Hemoglobin Changes After 6 Months of Treatment With Pioglitazone.
Takeda 326 participants Est. completion 2003-09 4 sitesOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT00449605
A Glycemic Control Evaluation of Glimepiride Versus Rimonabant on Top of Metformin in Type 2 Diabetes
Not yet reported Sanofi 508 participants Est. completion 2009-03 15 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00449930
Sitagliptin Comparative Study in Patients With Type 2 Diabetes (0431-049)
Not yet reported Merck Sharp & Dohme LLC 1050 participants Est. completion 2008-07-25Type 2 diabetesView official trial listing → -
Completed NCT NCT00451399
Efficacy of Lifestyle Interventions and Metformin for the Treatment of Antipsychotic-Induced Weight Gain
Not yet reported Central South University 128 participants Est. completion 2006-12 1 siteOther conditions: Weight GainView official trial listing → -
Completed NCT NCT00451568
Metformin and Oral Contraceptives in PCOS
Not yet reported Odense University Hospital 90 participants Est. completion 2013-04 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00454233
A Safety and Efficacy Study With YM543 in Type 2 Diabetes Mellitus Subjects
Not yet reported Astellas Pharma Inc 97 participants Est. completion 2008-06 6 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00460941
A Titration Study of a Glucagon-Like Peptide-1 (GLP-1) Analogue in Patients With Type 2 Diabetes Treated With Metformin.
Not yet reported Hoffmann-La Roche 133 participants Est. completion 2008-01 29 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT00461643
Strategies for Ovulation Induction in Anovulatory Infertile Patients With PCOS
Not yet reported University Magna Graecia 552 participants 3 sitesOther conditions: Anovulatory Infertility Related to Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00463502
The Effect of Metformin Treatment on Thyroid Hormone Metabolism in Euthyroid Patients With Type 2 Diabetes Mellitus
Not yet reported Haydarpasa Numune State HospitalType 2 diabetesView official trial listing → -
Status unknown NCT NCT00464594
Japan Early Diabetes Intervention Study
Not yet reported Japan Early Diabetes Intervention Study Group 2560 participants 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00466622
Uterine Artery Blood Flow in Pregnant Women With PCOS Treated With Metformin
Not yet reported Norwegian University of Science and Technology 48 participants Est. completion 2010-02 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00468039
A Sub-study to LMF237A2302 to Assess the Effect of 24 Weeks Treatment With Initial Combination of Vildagliptin Plus Metformin
Not yet reported Novartis 94 participants Est. completion 2008-06-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00469092
Comparison of Biphasic Insulin Aspart 30 Versus Insulin Glargine Both in Combination With Metformin and Glimepiride in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 480 participants Est. completion 2008-04 69 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT00469586
Efficacy and Safety of Inhaled Insulin Compared to Metformin and Glimepiride in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 174 participants Est. completion 2008-04-24 59 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00471523
Treatment of Anovulatory Infertility in PCOS Patients
Not yet reported University Magna Graecia 80 participants Est. completion 2007-03 1 siteOther conditions: Infertility, Polycystic Ovary Syndrome, AnovulationView official trial listing → -
Completed NCT NCT00473525
12 Week Study Of PF-00734200 For The Treatment Of Type 2 Diabetes Mellitus In Subjects Treated With Metformin
Not yet reported Pfizer 303 participants Est. completion 2008-06 79 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00473876
Metformin in Insulin Resistant Left Ventricular (LV) Dysfunction (TAYSIDE Trial)
Not yet reported University of Dundee 62 participants Est. completion 2009-04 1 siteHeart failure Other conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT00474838
Study To Evaluate Beta Cell Function and Glycemic Outcome by Intensive Insulin Therapy
Not yet reported Kyunghee University Medical Center 112 participants Est. completion 2012-12 8 sitesType 2 diabetes Other conditions: Pancreatic Beta Cell Function, GlucotoxicityView official trial listing → -
Terminated NCT NCT00479466
Dose-Range Finding Study for MK0893 (0893-008)
Not yet reported Merck Sharp & Dohme LLC 342 participants Est. completion 2008-05 Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT00481429
Predictive Markers of Glitazone Efficacy in Diabetic Patients - Pilot Study
Imperial College London Est. completion 2008-01 4 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00481663
A Study of Different Doses of Sitagliptin (MK-0431) in Participants With Type 2 Diabetes Mellitus (MK-0431-014)
Not yet reported Merck Sharp & Dohme LLC 555 participants Est. completion 2006-05-14Other conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT00482729
MK0431A Comparative Study in Patients With Type 2 Diabetes (0431A-079)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 1246 participants Est. completion 2009-04-27 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00483392
Treatment of Hyperglycaemia and Insulin Resistance in HIV Infected Patients
Not yet reported University Medical Centre Ljubljana 1 siteOther conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT00484419
Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin
Not yet reported Daiichi Sankyo 169 participants Est. completion 2008-04 20 sitesType 2 diabetes Other conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT00486187
Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study
Not yet reported Dr. Milan Gupta 103 participants Est. completion 2009-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00490178
Acceptability Study of a New Fixed Combination of Fenofibrate 80 mg BID and Metformin 1000 mg BID in Type 2 Diabetes and Dyslipidemia
Not yet reported Solvay Pharmaceuticals 29 participants 3 sitesType 2 diabetes Other conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT00491725
Efficacy and Safety of Repaglinide and Metformin Combination Therapy in Type 2 Diabetes Failing on Oral Anti-diabetic Drugs
Not yet reported Novo Nordisk A/S 187 participants Est. completion 2006-06 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00494312
Safety Study of Pioglitazone Compared To Glyburide on Liver Function
Not yet reported Takeda 2120 participants Est. completion 2005-06Other conditions: Diabetes Mellitus, LiverView official trial listing → -
Terminated NCT NCT00494663
A Phase 2b Study of DIO-902 or DIO-902 Placebo in Addition to Metformin and Atorvastatin or Atorvastatin Placebo for Type 2 Diabetes
Not yet reported DiObex 200 participants Est. completion 2008-12 24 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00494884
Vildagliptin 100 mg Once Daily vs. Placebo as add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Metformin
Not yet reported Novartis Est. completion 2008-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00499707
Efficacy and Safety Study of Rosiglitazone/Metformin Therapy vs Rosiglitazone and Metformin in Type 2 Diabetes Subjects
Not yet reported GlaxoSmithKline 453 participants Est. completion 2004-12-16 102 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00501020
Comparison of the Efficacy and Tolerability of the Addition of AVANDIA to Submaximal Doses of Metformin
Not yet reported GlaxoSmithKline 750 participants Est. completion 2003-02-13Type 2 diabetesView official trial listing → -
Status unknown NCT NCT00501904
Metformin in Infertile PCOS Patients
Not yet reported University Magna Graecia 20 participants Est. completion 2016-12 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Withdrawn NCT NCT00502229
Therapy for Infertile PCOS Patients Ovulating Under Clomiphene Citrate or Metformin
Not yet reported University Magna Graecia 1 siteOther conditions: Polycystic Ovary Syndrome, InfertilityView official trial listing → -
Completed NCT NCT00502710
A Study of Dipeptidyl-peptidase IV (DPP-IV) RO4876904 in Patients With Type 2 Diabetes.
Not yet reported Hoffmann-La Roche 289 participants Est. completion 2008-04 48 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00506194
Short-Term Intensive Insulin Therapy Induction of Long-term Glycemic Control
Not yet reported Taipei Veterans General Hospital, Taiwan 60 participants Est. completion 2011-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00506298
Study of CRx-401 on Glucose Levels in Subjects With Type II Diabetes
Not yet reported Zalicus 150 participants Est. completion 2009-05 18 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00510588
Chronic Inflammatory Activation in Fat Tissue: an Atherogenic Factor in Stable Coronary Artery Disease
Not yet reported University of Leipzig 120 participants Est. completion 2013-10 1 siteCardiovascular diseasePrediabetes Other conditions: ObesityView official trial listing → -
Terminated NCT NCT00510705
Chronic Inflammatory Activation in Fat Tissue: An Atherogenic Factor in Severe Coronary Artery Disease
Not yet reported University of Leipzig 29 participants 1 siteCardiovascular diseasePrediabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT00513630
Study on the Prognosis and Effect of Anti-diabetic Drugs on Type-2 Diabetes Mellitus With Coronary Artery Disease
Not yet reported Shanghai Jiao Tong University School of Medicine 304 participants Est. completion 2010-07 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00518882
Effect of Liraglutide or Exenatide Added to an Ongoing Treatment on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 467 participants Est. completion 2009-04 125 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00519142
Mitiglinide in Combination With Metformin vs. Metformin Alone in Patients With Type 2 Diabetes Mellitus
Not yet reported Elixir Pharmaceuticals 367 participants Est. completion 2008-10 61 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00519480
A Study To Assess The Safety And Tolerability Of GSK189075 When Given With A Total Daily Dose Of >/ 2000mg of Metformin
Not yet reported GlaxoSmithKline 50 participants Est. completion 2008-04-01 4 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00525330
A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of KRP-104 in Patients With Type 2 Diabetes Inadequately Controlled on Metformin Alone
Not yet reported ActivX Biosciences, Inc. 213 participants Est. completion 2008-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00528372
A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled With Diet and Exercise
Not yet reported AstraZeneca 1067 participants Est. completion 2010-07 78 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00528879
A Phase III Study of BMS-512148 (Dapagliflozin) in Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone
Not yet reported AstraZeneca 915 participants Est. completion 2010-05 75 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00532935
MK0431A vs. Pioglitazone in Patients With Type 2 Diabetes Mellitus (0431A-066)
Not yet reported Merck Sharp & Dohme LLC 517 participants Est. completion 2009-10-23 Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT00536211
Physical Inactivity and Insulin Resistance in Skeletal Muscle.
Not yet reported University of Kansas Medical Center Est. completion 2011-12 1 siteMetabolic syndrome Other conditions: Insulin Resistance, Hypertension, Hypercholesterolemia, ObesityView official trial listing → -
Completed NCT NCT00538486
A Randomized, Double-Blind, Active Control Trial Comparing Effects of Telmisartan, Candesartan and Amlodipine, Alone or Plus Metformin, on Non-Diabetic, Obese Hypertensive Patients
Not yet reported Third Military Medical University 360 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Hypertension, ObesityView official trial listing → -
Completed NCT NCT00541437
Type 2 Diabetes Patients Switched From Sulfonylurea With Metformin to Glyburide/Metformin Combination Tablet
Genovate Biotechnology Co., Ltd., 12 participants Est. completion 2007-02 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT00541567
BMS-646256 in Obese and Overweight Type 2 Diabetics
Not yet reported, Not yet reported Solvay Pharmaceuticals 600 participants Est. completion 2010-06Type 2 diabetesView official trial listing → -
Completed NCT NCT00541775
Safety/Efficacy of Sitagliptin in Patient w/ Type 2 Diabetes (0431-801)
Not yet reported Merck Sharp & Dohme LLC 273 participants Est. completion 2007-03 Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT00543361
Study MK0767 and Metformin in Type 2 Diabetic Patients (0767-020)
Not yet reported Merck Sharp & Dohme LLC 382 participants Est. completion 2003-12Type 2 diabetesView official trial listing → -
Terminated NCT NCT00543738
MK0767 and Metformin Combination Study (0767-028)
Not yet reported Merck Sharp & Dohme LLC 114 participants Est. completion 2003-12Other conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT00543751
Placebo Controlled Metformin and Sulfonylurea Combination Study in Patients With Type 2 Diabetes (0767-025)
Not yet reported Merck Sharp & Dohme LLC 610 participants Est. completion 2003-11Type 2 diabetesView official trial listing → -
Status unknown NCT NCT00544518
Impact of Benfluorex Versus Metformin on Glucose Control and Insulin Secretion in Chinese Type 2 Diabetic Patients
Not yet reported Air Force Military Medical University, China 240 participants Est. completion 2008-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00545584
Addition Of Januvia (Sitagliptin) Improves Glycemic Control In Patients Inadequately Controlled By Metformin (MK0431-078)
Not yet reported Merck Sharp & Dohme LLC 1512 participants Est. completion 2009-11-19Other conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00546442
Treatment Insulin Resistence in HCV G-1 Patient
Not yet reported Valme University Hospital 126 participants Est. completion 2007-01 19 sitesOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT00546728
The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes
Not yet reported St. Paul Heart Clinic 50 participants Est. completion 2011-07 2 sites Added to GLP-1PrediabetesView official trial listing → -
Completed NCT NCT00546741
Drug Interaction With Metformin
Not yet reported AstraZeneca 18 participants Est. completion 2008-02 1 siteOther conditions: Healthy Male and Female SubjectsView official trial listing → -
Completed NCT NCT00558077
Second-Line Treatments for Anovulatory Infertility in PCOS Patients
Not yet reported University Magna Graecia 50 participants Est. completion 2005-10 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Infertility, AnovulationView official trial listing → -
Completed NCT NCT00560690
The Effect of Adding Metformin to the Treatment of Hepatitis C
Not yet reported Tehran University of Medical Sciences 140 participants Est. completion 2010-12 1 site Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT00562172
Insulin Glargine (Lantus) vs Sulfonylurea (SU) for BETA Cell Function (BETA Study)
Not yet reported Sanofi 75 participants Est. completion 2010-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00568984
Efficacy and Safety of Repaglinide and Metformin Combined in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 324 participants Est. completion 2003-11-10 15 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00570739
Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.
Not yet reported Daiichi Sankyo 502 participants Est. completion 2009-05 31 sites Stand-aloneType 2 diabetesPrediabetes Other conditions: HypercholesterolemiaView official trial listing → -
Terminated NCT NCT00571519
Randomized, Double-blind, Active-controlled, Study of Rivoglitazone in Type 2 Diabetes Mellitus
Not yet reported Daiichi Sankyo 94 participants Est. completion 2008-05-23 18 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00575588
52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period
Not yet reported AstraZeneca 891 participants Est. completion 2010-08 94 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00577590
Effects of Fatty Acid Delivery on Heart Metabolism and Function in Type 2 Diabetes (T2DM
Not yet reported Washington University School of Medicine 78 participants Est. completion 2012-09 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT00580710
Investigation Into the Effects Upon Brain Response to Change in Circulating Glucose Levels in Diabetes Mellitus
Yale University 164 participants Est. completion 2018-11-01 1 siteOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Withdrawn NCT NCT00588172
Genetic Variation in OCT1 and Response to Metformin
Not yet reported Mayo Clinic Est. completion 2011-06Type 2 diabetesView official trial listing → -
Completed NCT NCT00592969
Efficacy and Safety of Metformin Plus Biphasic Insulin Aspart 30 in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 164 participants Est. completion 2004-11-02 2 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00598793
Biphasic Insulin Aspart 30 in Type 2 Diabetes Failing OAD Therapy
Not yet reported Novo Nordisk A/S 242 participants Est. completion 2004-03 27 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00601250
Efficacy and Safety of B I1356 (Linagliptin) vs. Placebo Added to Metformin Background Therapy in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 701 participants 82 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00602472
BI 1356 (Linagliptin) in Combination With Metformin and a Sulphonylurea in Type 2 Diabetes
Not yet reported Boehringer Ingelheim 1058 participants 100 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00603239
Safety and Efficacy of Exenatide in Patients With Type 2 Diabetes Using a Thiazolidinedione or a Thiazolidinedione and Metformin
Not yet reported AstraZeneca 165 participants Est. completion 2009-07 25 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00605475
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACZ885 in Patients With Type 2 Diabetes
Not yet reported Novartis 231 participants Est. completion 2010-09 13 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT00607867
LoBAG30 Diet in Patients on Metformin
Not yet reported US Department of Veterans Affairs 20 participants Est. completion 2011-03 1 siteOther conditions: Diabetes Mellitus, DietView official trial listing → -
Completed NCT NCT00611884
Comparison of Two NN1250 Formulations Versus Insulin Glargine, All in Combination With Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 245 participants Est. completion 2008-08 29 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00613951
Comparison of Two NN5401 Formulations Versus Biphasic Insulin Aspart 30, All in Combination With Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 182 participants Est. completion 2008-08 31 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00614120
Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 929 participants Est. completion 2009-02 50 sites MixedType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00617240
Strategies to Reduce Antipsychotic-Associated Weight Gain in Youth
Not yet reported University of North Carolina, Chapel Hill 9 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: Weight GainView official trial listing → -
Completed NCT NCT00618007
Effect of PF-00734200 in Subjects With Type 2 Diabetes
Not yet reported Pfizer 289 participants Est. completion 2008-08 79 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00618072
EMPOWIR:Enhance the Metabolic Profile of Women With Insulin Resistance
Not yet reported New York Medical College 46 participants Est. completion 2011-01 1 siteOther conditions: Hyperinsulinemia, Insulin Resistance, ObesityView official trial listing → -
Completed NCT NCT00619697
Efficacy and Safety of Biphasic Insulin Aspart 30 in Combination With Metformin in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 260 participants Est. completion 2005-03 54 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00620191
Metformin in Amnestic Mild Cognitive Impairment
Not yet reported Columbia University 80 participants Est. completion 2012-02 1 site Stand-aloneOther conditions: Mild Cognitive ImpairmentView official trial listing → -
Terminated NCT NCT00622089
Open Label Safety & Pharmacodynamic Study 24Wk w/DIO-902 Combo w/Metformin & Atorvastatin in T2DM Patients
Not yet reported, Not yet reported DiObex 150 participants Est. completion 2008-12 24 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00622284
Efficacy and Safety of BI 1356 in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 1560 participants 221 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00622323
Post Marketing Surveillance Study of Byetta ™ (Exenatide) Use Among Filipino Patients
AstraZeneca 41 participants Est. completion 2009-09 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00624364
Efficacy and Safety of Biphasic Insulin Aspart 30 With Metformin in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 140 participants Est. completion 2005-05 15 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00627445
Effect of Biphasic Insulin Aspart 50 on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 441 participants Est. completion 2009-01 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00631007
A Placebo Controlled Safety and Efficacy Study of INT131 Besylate in Type 2 Diabetes, With an Active Comparator
Not yet reported InteKrin Therapeutics, Inc. 367 participants Est. completion 2009-09 66 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00631033
DZX Mediated Insulin Suppression in Obese Men
Not yet reported Rijnstate Hospital 51 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT00631488
A Study to Test the Effectiveness and Safety of MK0893 in Combination With Other Drugs Used to Treat Type 2 Diabetes (0893-015)
Not yet reported Merck Sharp & Dohme LLC 146 participants Est. completion 2009-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00633425
Continuous Glucose Monitoring System (CGMS) in Type 2 Diabetic Patients Inadequately Controlled by Metformine Monotherapy; Analyze of Glycemic Profile Before and After Association of Glimepiride
Not yet reported Sanofi 43 participants Est. completion 2003-10 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00636766
Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque
Not yet reported Aristotle University Of Thessaloniki 300 participants Est. completion 2009-01 1 site Stand-aloneCardiovascular diseaseType 2 diabetesMetabolic syndrome Other conditions: Carotid AtherosclerosisView official trial listing → -
Completed NCT NCT00637273
A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)
Not yet reported AstraZeneca 514 participants Est. completion 2009-07 62 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00638716
A Study to Evaluate the Efficacy and Safety of CJC-1134-PC in Patients With Type 2 Diabetes Mellitus Who Are Currently on Metformin Monotherapy
Not yet reported ConjuChem 122 participants Est. completion 2008-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00641056
Efficacy of Exenatide Once Weekly and Once-Daily Insulin Glargine in Patients With Type 2 Diabetes Treated With Metformin Alone or in Combination With Sulfonylurea (DURATION - 3)
Not yet reported AstraZeneca 467 participants Est. completion 2009-11 75 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00641407
Bedtime Insulins and Oral Antihyperglycemic Drugs in Type 2 Diabetes
Not yet reported University of Campania Luigi Vanvitelli 100 participants Est. completion 2008-03 1 siteType 2 diabetes Other conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT00642278
An Efficacy, Safety, and Tolerability Study of Canagliflozin (JNJ-28431754) in Patients With Type 2 Diabetes
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 451 participants Est. completion 2009-01 78 sitesOther conditions: Diabetes Mellitus, Type II, Diabetes Mellitus, Non Insulin DependentView official trial listing → -
Completed NCT NCT00643851
An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release Tablets
Not yet reported AstraZeneca 994 participants Est. completion 2009-08 99 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT00647023
Incretin Secretion in Women With Polycystic Ovary Syndrome (PCOS)
Not yet reported Hvidovre University Hospital 66 participants Est. completion 2006-05 Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00648492
Food Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR 500 mg
Not yet reported Mylan Pharmaceuticals Inc 18 participants Est. completion 2002-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00648505
Food Study of Glipizide and Metformin HCl Tablets 5 mg/500 mg to Metaglip® Tablets 5 mg/500 mg
Not yet reported Mylan Pharmaceuticals Inc 36 participants Est. completion 2005-06 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00648518
Fasting Study of Metformin Hydrochloride ER Tablets 750 mg and Glucophage® XR Tablets 750 mg
Not yet reported Mylan Pharmaceuticals Inc 36 participants Est. completion 2003-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT00648869
Open-label Crossover Metformin Gum Versus Tablet in Healthy Volunteers
Not yet reported Hadassah Medical Organization 12 participants Est. completion 2008-11 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00649350
Food Study Metformin Hydrochloride ER Tablets 750 mg and Glucophage XR 750 mg
Not yet reported Mylan Pharmaceuticals Inc 28 participants Est. completion 2003-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00649454
Fasting Study of Glipizide and Metformin HCl Tablets 5 mg/500 mg to Metaglip® Tablets 5 mg/500 mg
Not yet reported Mylan Pharmaceuticals Inc 36 participants Est. completion 2005-06 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00649948
Food BE Study Metformin Hydrochloride ER Tablets 500 mg and Glucophage XR 500 mg
Not yet reported Mylan Pharmaceuticals Inc 27 participants Est. completion 2004-06 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00650234
Fasting BE Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg
Not yet reported Mylan Pharmaceuticals Inc 47 participants Est. completion 2004-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00650312
Fasting Study of Metformin Hydrochloride ER Tablets 500 mg and Glucophage® XR Tablets 500 mg
Not yet reported Mylan Pharmaceuticals Inc 50 participants Est. completion 2002-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00653185
Efficacy of SYR-472 in Subjects With Type 2 Diabetes Mellitus
Not yet reported Takeda 369 participants Est. completion 2008-03 87 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00653302
Phenotype Evaluation in Insulin Naive Patients Using Lantus (Insulin Glargine)
Not yet reported Sanofi 280 participants Est. completion 2005-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00657943
The Copenhagen Insulin and Metformin Therapy Trial
Not yet reported Steno Diabetes Center Copenhagen 415 participants Est. completion 2012-12 9 sites Stand-aloneType 2 diabetes Other conditions: Atherosclerosis, ArteriosclerosisView official trial listing → -
Completed NCT NCT00660907
Efficacy and Safety of Dapagliflozin in Combination With Metformin in Type 2 Diabetes Patients
Not yet reported AstraZeneca 1217 participants Est. completion 2013-01 76 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00661362
Evaluate Efficacy and Safety of Saxagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes
Not yet reported AstraZeneca 570 participants Est. completion 2009-09 30 sites Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT00661921
A Randomized Double Blind, Placebo Controlled Trial With AMG 108 in Patients With Type 2 Diabetes Mellitus
Not yet reported Amgen Est. completion 2009-10Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00664846
Standard Medical Management in Secondary Prevention of Ischemic Stroke in China
Not yet reported Peking Union Medical College Hospital 4000 participants Est. completion 2011-04 46 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00666458
18-week add-on to Metformin Comparison of Saxagliptin and Sitagliptin in Adult Patients With Type 2 Diabetes (T2D)
Not yet reported AstraZeneca 822 participants Est. completion 2009-03 87 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00667498
Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance
Not yet reported Yale University 28 participants Est. completion 2007-12 1 site Stand-aloneOther conditions: Pediatric Obesity, Insulin Resistance, HyperinsulinemiaView official trial listing → -
Completed NCT NCT00667732
How Glargine Insulin, Oral Diabetes Medications and Exenatide May Improve Blood Sugar Control and Weight Gain in Type 2 Diabetics
Not yet reported Oregon Health and Science University 41 participants Est. completion 2010-04 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00669864
Effect of Biphasic Insulin Aspart 30 Combined With Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin
Not yet reported Novo Nordisk A/S 293 participants Est. completion 2009-04 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00670800
Study of Brain Function in Women With Insulin Resistant Polycystic Ovary Syndrome
Not yet reported University of Michigan 14 participants Est. completion 2009-08 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00672386
A Study of the Safety and Effectiveness of a R256918 in Patients With Type 2 Diabetes
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 352 participants Est. completion 2008-09 62 sites Stand-aloneType 2 diabetes Other conditions: Diabetes Mellitus, Endocrine System Diseases, Nutritional and Metabolic DiseasesView official trial listing → -
Withdrawn NCT NCT00672464
Cardio Risk of Acute Schizophrenia Olanzapine Duke
Not yet reported Duke University Est. completion 2010-02 2 sites Stand-aloneOther conditions: Schizophrenia, Schizoaffective DisorderView official trial listing → -
Completed NCT NCT00673465
Effect of SCH 497079 on Metabolic Parameters and Influence of Race/Ethnic Origin on Therapeutic Response (Study P05338)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 17 participants Est. completion 2008-12-11 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00674466
A Study to Evaluate the Efficacy and Safety of CJC-1134-PC in Patients With Type 2 Diabetes Who Are Currently on Metformin Monotherapy
Not yet reported ConjuChem 90 participants Est. completion 2008-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00676338
Safety and Efficacy of Exenatide Once Weekly Injection Versus Metformin, Dipeptidyl Peptidase-4 Inhibitor, or Thiazolidinedione as Monotherapy in Drug-Naive Patients With Type 2 Diabetes (DURATION-4)
Not yet reported AstraZeneca 820 participants Est. completion 2011-01 106 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00678080
Metformin Versus Insulin in Pregnant Women With Type 2 Diabetes
Not yet reported The University of Texas Health Science Center, Houston 25 participants Est. completion 2011-08 3 sites Stand-aloneOther conditions: Pregnancy ComplicationsView official trial listing → -
Completed NCT NCT00679237
Risk Reduction in Coronary Heart Disease
Not yet reported Sorlandet Hospital HF 1600 participants Est. completion 2019-12 1 siteOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00679939
Study In Postmenopausal Women With Type 2 Diabetes Looking At Approved Diabetes Drugs And How They Affect Bone Health
Not yet reported GlaxoSmithKline 226 participants Est. completion 2010-09-16 42 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00680745
Efficacy and Safety of Dapagliflozin in Combination With Glimepiride (a Sulphonylurea) in Type 2 Diabetes Patients
Not yet reported AstraZeneca 597 participants Est. completion 2010-05 66 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00681460
Metformin in Gestational Diabetes Mellitus
Not yet reported K. Marcinkowski University of Medical Sciences 78 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Diabetes, Gestational, Insulin ResistanceView official trial listing → -
Completed NCT NCT00682448
Metformin for the Prevention of the Metabolic Side-effects of Zyprexa
Not yet reported Rush University Medical Center 25 participants Est. completion 2011-08 1 siteOther conditions: Metabolic ComplicationsView official trial listing → -
Terminated NCT NCT00682890
Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS)
Not yet reported Virginia Commonwealth University 28 participants Est. completion 2010-01 1 siteOther conditions: Polycystic Ovary Syndrome, PCOS, Insulin SensitivityView official trial listing → -
Completed NCT NCT00683657
Safety and Efficacy Study of Subjects That Are Taking Saxagliptin Added Onto Metformin XR Compared to Subjects Taking Metformin XR Alone
Not yet reported AstraZeneca 93 participants Est. completion 2009-02 27 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00683735
Quantification of the Dipeptidyl Peptidase (DPP)-4 Inhibition-mediated Enhancement of the Activity of the Entero-insular Axis
Not yet reported, Not yet reported Michael A. Nauck 20 participants Est. completion 2013-12 1 siteOther conditions: DiabetesView official trial listing → -
Status unknown NCT NCT00684528
A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin
Not yet reported Meir Medical Center 1000 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT00686634
Sitagliptin in Combination With Metformin and Sulfonylurea
Not yet reported Charles Drew University of Medicine and Science 108 participants Est. completion 2010-03 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00690456
Effect of Rimonabant and Metformin Combination on Glycemic Control in Patients With Type 2 Diabetes
Not yet reported Sanofi 403 participants Est. completion 2009-02 13 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00690755
Defective Atypical Protein Kinase C (PKC) Activation in Diabetes and Metabolic Syndrome
VA Office of Research and Development 157 participants Est. completion 2012-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00691314
Efficacy and Safety of Stent Implantation in Symptomatic Extra- and Intracranial Artery Stenosis
Not yet reported Peking Union Medical College Hospital 300 participants Est. completion 2010-12 10 sites Stand-aloneCardiovascular disease Other conditions: Transient Ischemic Attack, Atherosclerosis, Stenosis, StentsView official trial listing → -
Completed NCT NCT00694057
Safety, Tolerance and Activity of HE3286 in Patients With Type 2 Diabetes Mellitus
Not yet reported Harbor Therapeutics 164 participants Est. completion 2010-01 22 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00694759
Cortisol Regulation in Polycystic Ovary Syndrome (PCOS)
Not yet reported Oregon Health and Science University 37 participants Est. completion 2011-07 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00696657
A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and Liraglutide
Not yet reported Novo Nordisk A/S 415 participants Est. completion 2009-02-05 77 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT00696982
The Effect of Sitagliptin on Hypertension, Arterial Stiffness, Oxidative Stress and Inflammation
Not yet reported Assaf-Harofeh Medical Center 60 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Diabetes Mellitus, Arterial StiffnessView official trial listing → -
Completed NCT NCT00698230
Safety and Efficacy of INCB013739 Plus Metformin Compared to Metformin Alone on Glycemic Control in Type 2 Diabetics
Not yet reported Incyte Corporation 302 participants Est. completion 2009-05 68 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT00698789
Evaluate the Safety and Tolerability of INCB019602 When Administered With Metformin in Patients With Type 2 Diabetes
Not yet reported Incyte Corporation 48 participants Est. completion 2009-06 22 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT00699036
Rosiglitazone Versus Rosiglitazone and Metformin Versus Rosiglitazone and Avandia in the Treatment of Nonalcoholic Steatohepatitis (NASH)
Not yet reported Brooke Army Medical Center 165 participants Est. completion 2009-08 1 site Stand-aloneMASHMASLDView official trial listing → -
Status unknown NCT NCT00699322
Effect of Dipeptidyl Peptidase-IV Inhibitor and Sulfonylurea on Glucose Variability and Oxidative Stress
Not yet reported The Catholic University of Korea 36 participants Est. completion 2010-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00700817
The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 665 participants Est. completion 2010-06 166 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT00700856
Thiazolidinediones Or Sulphonylureas and Cardiovascular Accidents.Intervention Trial
Not yet reported Italian Society of Diabetology 3371 participants Est. completion 2018-12 61 sites Stand-aloneType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00701090
A Study to Test the Safety and Efficacy of Sitagliptin Compared to Glimepiride in Patients With Type 2 Diabetes on a Stable Dose of Metformin (0431-803)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 1035 participants Est. completion 2009-10 Stand-aloneType 2 diabetes Other conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Terminated NCT NCT00701935
Effect of Exenatide on Abdominal Fat Distribution in Patients With Type 2 Diabetes Pretreated With Metformin
Not yet reported AstraZeneca 80 participants Est. completion 2012-01 17 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00703508
Pharmacogenetics of Metformin Action in PCOS
Not yet reported Virginia Commonwealth University 55 participants Est. completion 2014-03 2 sites Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00703755
A Randomized, Double-Blind Trial Comparing the Efficacy and Safety of Fenofibrate, Metformin, Their Combination and Placebo in Patients With Metabolic Syndrome.
Not yet reported Solvay Pharmaceuticals 2288 participants Est. completion 2004-06 101 sites Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT00707031
GLP-1 Receptor Agonist Lixisenatide Versus Exenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin
Not yet reported Sanofi 639 participants Est. completion 2010-11 18 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00708578
Optimal Oral Hypoglycaemic Agents (OHA) for Combination With Insulin Glargine (Sulfonylurea vs. Metformin)
Not yet reported Sanofi 99 participants Est. completion 2009-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00709917
Observational Study of the Switch of Metformin Alone to Metformin Combined With Repaglinide in Type 2 Diabetes
Novo Nordisk A/S 2171 participants Est. completion 2008-01 2 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00712673
GLP-1 Receptor Agonist Lixisenatide (Morning or Evening) in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin
Not yet reported Sanofi 680 participants Est. completion 2011-03 16 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00713830
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Sulfonylurea
Not yet reported Sanofi 859 participants Est. completion 2011-01 16 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00714233
Treatment of Adolescent Polycystic Ovary Syndrome (PCOS)
Not yet reported University of Rochester 43 participants Est. completion 2007-12 Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00715624
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Basal Insulin
Not yet reported Sanofi 496 participants Est. completion 2011-02 15 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00717457
A Study of Taspoglutide Versus Exenatide for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin, Thiazolidinedione or a Combination of Both.
Not yet reported Hoffmann-La Roche 1189 participants Est. completion 2011-03 216 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00720161
Metformin in Children With Motor Deficit
Not yet reported Universitaire Ziekenhuizen KU Leuven 42 participants Est. completion 2011-07 1 siteOther conditions: Spina Bifida, Neuromuscular DiseasesView official trial listing → -
Completed NCT NCT00722371
MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2)
Not yet reported Merck Sharp & Dohme LLC 1615 participants Est. completion 2011-03-25 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00723307
Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study
Not yet reported Professor Naveed Sattar 173 participants Est. completion 2012-12 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00727857
Efficacy and Safety of Pioglitazone and Metformin Combination Therapy in Treating Type 2 Diabetes Mellitus.
Not yet reported Takeda 600 participants Est. completion 2008-08 77 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00729326
Comparison of the Effect of Exenatide Versus Sitagliptin on 24-hour Average Glucose in Patients With Type 2 Diabetes on Metformin or a Thiazolidinedione
Not yet reported AstraZeneca 83 participants Est. completion 2009-10 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00736385
Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)
Not yet reported Duke University 11 participants Est. completion 2012-12 1 siteOther conditions: Fatty LiverView official trial listing → -
Completed NCT NCT00740051
A Randomised, db, Placebo-controlled Study of BI 1356 for 18 Weeks Followed by a 34 Week Double-blind Extension Period (Placebo Patients Switched to Glimepiride) in Type 2 Diabetic Patients for Whom Treatment With Metformin is Inappropriate
Not yet reported Boehringer Ingelheim 227 participants 53 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00743002
A Trial of TT223 in Patients With Type 2 Diabetes Who Are Taking Metformin and/or Thiazolidinedione
Not yet reported OPKO Health, Inc. 87 participants Est. completion 2009-12 20 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00744367
A Study of Taspoglutide Versus Placebo for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Plus Pioglitazone.
Not yet reported Hoffmann-La Roche 326 participants Est. completion 2010-11 113 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00745433
Switch From Metformin Monotherapy to a Bitherapy With Metformin and Repaglinide
Novo Nordisk A/S 906 participants Est. completion 2009-03 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00749190
BI 10773 add-on to Metformin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 495 participants 116 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00751114
Evaluation of Insulin Glargine Versus Sitagliptin in Insulin-naive Patients
Not yet reported Sanofi 515 participants Est. completion 2011-07 17 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00753896
Safety of Exenatide Once Weekly in Patients With Type 2 Diabetes Mellitus Treated With Thiazolidinedione Alone or Thiazolidinedione in Combination With Metformin
Not yet reported AstraZeneca 134 participants Est. completion 2009-11 26 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00754403
Efficacy of Pioglitazone and Fortamet Combination Therapy in Subjects With Type 2 Diabetes
Not yet reported Takeda 312 participants Est. completion 2006-10 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Withdrawn NCT NCT00754689
Study of Rimonabant/Metformin Combinations to Investigate Diabetes (Blood Sugar) Control in Patients With Type 2 Diabetes
Not yet reported Sanofi Est. completion 2008-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00754988
A Study of Taspoglutide Versus Sitagliptin for the Treatment of Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin.
Not yet reported Hoffmann-La Roche 666 participants Est. completion 2011-03 148 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00755287
A Study of the Safety, Tolerability and Effect on Glycemic Control of Taspoglutide Versus Insulin Glargine in Insulin Naive Type 2 Diabetic Patients Inadequately Controlled With Metformin Plus Sulphonylurea.
Not yet reported Hoffmann-La Roche 1072 participants Est. completion 2010-12 210 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00755846
Safety and Efficacy Study of Alogliptin on Glycemic Control in Subjects With Type 2 Diabetes.
Not yet reported Takeda 265 participants Est. completion 2005-10Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00757588
Safety and Efficacy of Saxagliptin Plus Insulin With or Without Metformin
Not yet reported AstraZeneca 455 participants Est. completion 2010-04 80 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00760344
Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus
Not yet reported Takeda 386 participants Est. completion 2008-03 112 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT00762957
Safety and Efficacy of TAK-559 in Combination With Metformin in Patients With Type 2 Diabetes Mellitus.
Not yet reported Takeda 15 participants Est. completion 2004-12 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00763451
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Metformin
Not yet reported Sanofi 484 participants Est. completion 2011-01 15 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00763815
GLP-1 Receptor Agonist Lixisenatide in Patients With Type 2 Diabetes for Glycemic Control and Safety Evaluation, on Top of Pioglitazone
Not yet reported Sanofi 484 participants Est. completion 2011-06 150 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00765817
Addition Of Exenatide To Insulin Glargine In Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 261 participants Est. completion 2010-01 59 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00767000
Dose Range Finding Study of MK-0941 in Patients With Type 2 Diabetes Mellitus on Insulin (MK-0941-007 AM3 EXT1 AM1)(TERMINATED)
Not yet reported Merck Sharp & Dohme LLC 813 participants Est. completion 2010-06 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00767351
Variation in Serum Levels of Metformin in Patients With Reduced Renal Function
Skane University Hospital 30 participants Est. completion 2009-07Type 2 diabetes Other conditions: Metformin, PharmacokineticsView official trial listing → -
Completed NCT NCT00770445
Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus.
Not yet reported Takeda 121 participants Est. completion 2010-07 18 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00770653
Efficacy of Pioglitazone/Metformin Combination Therapy in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia.
Not yet reported Takeda 305 participants Est. completion 2009-05 64 sites Stand-aloneOther conditions: Diabetes Mellitus, DyslipidemiasView official trial listing → -
Completed NCT NCT00770835
Efficacy and Safety of Pioglitazone in Treating Subjects With Vascular Complications Associated With Type 2 Diabetes Mellitus.
Not yet reported Takeda 39 participants Est. completion 2011-05 2 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00772174
Efficacy and Safety Study of Pioglitazone Combined With Metformin on Metabolic Syndrome in Subjects With Type 2 Diabetes
Not yet reported Takeda 418 participants Est. completion 2008-02 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00774553
To Evaluate Safety and Tolerability After Multiple Oral Doses of AZD1656 in Type 2 Diabetes Patients on Top of Metformin
Not yet reported AstraZeneca 70 participants Est. completion 2010-01 2 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT00775164
Pioglitazone Therapy in Obese Children With Insulin Resistance: A Randomized, Controlled Pilot Study
Not yet reported University of Minnesota Est. completion 2011-02Other conditions: Obesity, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT00776607
Randomized Controlled Trial of Insulin Versus Tablets for Latent Autoimmune Diabetes in Adults (LADA)
Not yet reported Abertawe Bro Morgannwg University NHS Trust 200 participants Est. completion 2011-04 2 sitesOther conditions: Latent Autoimmune Diabetes in Adults LADAView official trial listing → -
Completed NCT NCT00778141
Bioequivalence Study of Metformin HCl 750 mg XR Tablets Under Non Fasting Conditions
Not yet reported Ranbaxy Laboratories Limited 36 participants Est. completion 2004-06 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00778349
A Comparitive Bioavailability Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fasting Conditions and After Low and High Fat Meal
Not yet reported Ranbaxy Laboratories Limited 34 participants Est. completion 2002-07 Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00778427
Bioequivalence Study of Metformin Hydrochloride 1000mg Tablets Under Fasting Conditions
Not yet reported Ranbaxy Laboratories Limited 32 participants Est. completion 2006-04 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00778466
Bioequivalence Study of Metformin Hydrochloride 1000mg Tablets Under Fed Conditions
Not yet reported Ranbaxy Laboratories Limited 32 participants Est. completion 2006-04 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00778791
Bioequivalence Study of Metformin HCl 750 mg XR Under Fasting Conditions
Not yet reported Ranbaxy Laboratories Limited 60 participants Est. completion 2004-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00780013
Bioequivalence Study of Metformin Hydrochloride Liquid 500mg/ 5 mL Under Fed Conditions
Not yet reported Ranbaxy Laboratories Limited 36 participants Est. completion 2002-06 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00780715
Response To Oral Agents in Diabetes (ROAD)- Pilot Study
Not yet reported University of Dundee 29 participants Est. completion 2009-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00783744
Insulin Glargine Combination Therapies in Type II Diabetics
Not yet reported Sanofi 375 participants 10 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00789035
12 Weeks Treatment With 3 Different Doses of BI 10773 in Type 2 Diabetic Patients
Not yet reported Boehringer Ingelheim 408 participants 74 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00789191
Effect of Detemir and Sitagliptin on Blood Glucose Control in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 222 participants Est. completion 2009-08 51 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT00790348
Effect of Januvia on Ghrelin and Other Gut Hormones in Patients With Diabetes
Wayne State University 45 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00792935
A Study to Test MK-0941 in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-0941-017)
Not yet reported Merck Sharp & Dohme LLC 143 participants Est. completion 2010-02 Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT00794963
Aggressive Treatment of Metabolic Syndrome in Patients Receiving Clozapine for Schizophrenia
Not yet reported Northwell Health 8 participants Est. completion 2010-05 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT00795808
PCOSMIC Trial - PolyCystic Ovary Syndrome, Metformin for Infertility With Clomiphene
Not yet reported University of Auckland, New Zealand 171 participants Est. completion 2008-10 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00798161
Safety and Efficacy of Linagliptin (BI 1356) Plus Metformin in Type 2 Diabetes, Factorial Design
Not yet reported Boehringer Ingelheim 857 participants 138 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00802100
Comparison of Optimal Antipsychotic Treatments for Adults With Schizophrenia
Not yet reported National Institute of Mental Health (NIMH) 21 participants Est. completion 2009-10 13 sites Stand-aloneOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT00806234
Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics
Not yet reported Johns Hopkins University 127 participants Est. completion 2014-03 4 sites Stand-aloneOther conditions: Psychotic DisordersView official trial listing → -
Completed NCT NCT00806520
Use of Continuous Glucose Monitoring Combined With Ambulatory Glucose Profiles to Characterize Glycemic Control
HealthPartners Institute 16 participants Est. completion 2011-08 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00807092
Comparing the Efficacy and Safety of Biphasic Insulin Aspart 30 and Biphasic Human Insulin 30 on Blood Sugar Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 145 participants Est. completion 2009-10 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT00809536
Investigation Of How PD 0332334 And Metformin Are Eliminated From The Body When They Are Administered At The Same Time
Not yet reported Pfizer 24 participants Est. completion 2009-02 1 siteOther conditions: Generalized Anxiety DisorderView official trial listing → -
Completed NCT NCT00813995
A Study to Test the Safety and Efficacy of Adding Sitagliptin in Patients With Type 2 Diabetes Mellitus (MK0431-074)
Not yet reported Merck Sharp & Dohme LLC 395 participants Est. completion 2010-08-09 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00814294
Study of Two Doses of Oral HDV-Insulin and Placebo With Background Metformin Treatment in Patients With Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Diasome Pharmaceuticals 239 participants Est. completion 2009-09 40 sitesOther conditions: DiabetesView official trial listing → -
Terminated NCT NCT00814372
Evaluate Safety and Effectiveness of MBX-102 in Type 2 Diabetes Patients With Poor Glycemic Control on Metformin
Not yet reported Gilead Sciences 242 participants Est. completion 2010-02 26 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00815399
Pioglitazone Versus Metformin in Type 2 Diabetes
Not yet reported University of Campania Luigi Vanvitelli 150 participants Est. completion 2015-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00816907
The Use of Metformin in the Treatment of Antipsychotic-Induced Weight Gain in Schizophrenia (The METS Study)
Not yet reported National Institute of Mental Health (NIMH) 146 participants Est. completion 2010-03 16 sites Stand-aloneOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT00817271
To Evaluate the Response to Glucagon During Hypoglycemia
Not yet reported AstraZeneca 8 participants Est. completion 2009-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00817778
Study to Assess the Safety and Tolerability After Multiple Oral Doses of AZD1656 in Patients With Type 2 Diabetes Mellitus Treated With Metformin
Not yet reported AstraZeneca 27 participants Est. completion 2009-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00818077
Using Continuous Glucose Monitoring to Understand the Glycemic Impact of Food
HealthPartners Institute 15 participants Est. completion 2010-09 1 siteType 2 diabetes Other conditions: Currently Taking MetforminView official trial listing → -
Completed NCT NCT00819325
Prevention of Instent Renarrowing With Aggressive Glucose Lowering With Pioglitazone in Diabetic Patients
Not yet reported Queen Elizabeth II Health Sciences Centre 50 participants Est. completion 2007-03 1 site Stand-aloneCardiovascular diseaseType 2 diabetes Other conditions: Angina Pectoris, Percutaneous Coronary InterventionView official trial listing → -
Completed NCT NCT00819741
Comparison of the Blood Sugar Lowering Effect Between Repaglinide Plus Metformin and Repaglinide Alone in Type 2 Diabetics Not Previously Treated With Oral Sugar-lowering Drugs
Not yet reported Novo Nordisk A/S 433 participants Est. completion 2009-11 17 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00819884
To Evaluate 24-hr Glucose After OD vs BD AZD1656
Not yet reported AstraZeneca 36 participants Est. completion 2009-05 1 siteOther conditions: Type II DiabetesView official trial listing → -
Completed NCT NCT00820573
Mechanisms of Glucose Lowering Effects of Sitagliptin and Metformin Alone and in Combination in Patients With T2DM
Not yet reported The University of Texas Health Science Center at San Antonio 16 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00822211
Efficacy of add-on Therapy With Vildagliptin in Chinese Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy
Not yet reported Novartis 404 participants Est. completion 2009-12 17 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00823680
A Study of RO5093151 and RO5027838 in Patients With Type 2 Diabetes Mellitus on a Stable Dose of Metformin
Not yet reported Hoffmann-La Roche 110 participants Est. completion 2009-08 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00823992
A Study of Taspoglutide Versus Placebo for the Treatment of Obese Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Monotherapy
Not yet reported Hoffmann-La Roche 305 participants Est. completion 2010-05 71 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00830076
A Study of the Effects of Co-Administration of Sitagliptin (MK-0431) and Metformin on Incretin Hormone Concentrations (MK-0431-110)
Not yet reported Merck Sharp & Dohme LLC 18 participants Est. completion 2009-05-14 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00832390
Study to Assess the Efficacy and Safety of Sitagliptin in Recently Diagnosed, Naive Type 2 Diabetics With Inadequate Glycemic Control on Diet and Exercise (0431-158)
Not yet reported Merck Sharp & Dohme LLC 29 participants Est. completion 2008-07-11 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT00832481
Comparison of the Effects of Repaglinide and Metformin on Glucose Excursions
Not yet reported Chinese PLA General Hospital 60 participants Est. completion 2009-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00833027
ALPHA Sitagliptin Add on to Metformin (0431-103)
Not yet reported Merck Sharp & Dohme LLC 608 participants Est. completion 2009-10-30Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00834587
5 mg Glipizide/500 mg Metformin Hydrochloride Tablets, Non-Fasting
Not yet reported Teva Pharmaceuticals USA 40 participants Est. completion 2004-06 2 sites Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00834613
Metformin ER 750 mg Tablets, Fed
Not yet reported Teva Pharmaceuticals USA 32 participants Est. completion 2003-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00834652
Adding an Insulin-Sensitizing Medication to Depression Treatment for People Who Are Depressed and Overweight
Not yet reported Washington University School of Medicine 206 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: DepressionView official trial listing → -
Completed NCT NCT00834743
Metformin ER 750 mg Tablets, Fasting
Not yet reported Teva Pharmaceuticals USA 32 participants Est. completion 2003-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00835497
5 mg Glipizide/500 mg Metformin Hydrochloride Tablets, Fasting
Not yet reported Teva Pharmaceuticals USA 40 participants Est. completion 2004-06 2 sites Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00835861
Effectiveness of Metformin Compared to Insulin in Pregnant Women With Mild Preexisting or Early Gestational Diabetes
Not yet reported University of North Carolina, Chapel Hill 31 participants Est. completion 2010-04 1 site Stand-aloneOther conditions: Non Insulin Dependent Diabetes, PregnancyView official trial listing → -
Completed NCT NCT00835991
Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fed
Not yet reported Teva Pharmaceuticals USA 60 participants Est. completion 2003-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00836472
Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fasting
Not yet reported Teva Pharmaceuticals USA 60 participants Est. completion 2003-04 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00838903
Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes
Not yet reported GlaxoSmithKline 1049 participants Est. completion 2013-04 386 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00839527
A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes
Not yet reported GlaxoSmithKline 685 participants Est. completion 2013-04 358 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00842140
Safety of Hormonal Contraceptives Therapies in Polycystic Ovary Syndrome (PCOS) Women
Not yet reported University of Sao Paulo 75 participants Est. completion 2009-01 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00842400
A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.
Not yet reported VIVUS LLC 20 participants Est. completion 2009-04 1 siteOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT00845936
Metformin for Weight Control in Adolescents Taking Atypical Antipsychotics
Not yet reported BeerYaakov Mental Health Center 30 participants Est. completion 2010-05 1 site Stand-aloneOther conditions: Drug Induced Weight GainView official trial listing → -
Completed NCT NCT00849056
Safety and Efficacy of Albiglutide in Type 2 Diabetes
Not yet reported GlaxoSmithKline 310 participants Est. completion 2013-01 331 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00851903
Evaluation of Insulin Glargine in Combination With Sitagliptin in Type 2 Diabetes Patients: EASIE Extension Trial
Not yet reported Sanofi 112 participants Est. completion 2011-09 16 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00855166
Evaluation of the Effect of Dapagliflozin in Combination With Metformin on Body Weight in Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 182 participants Est. completion 2011-12 21 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00856284
Efficacy and Safety of Alogliptin Plus Metformin Compared to Glipizide Plus Metformin in Patients With Type 2 Diabetes Mellitus
Not yet reported Takeda 2639 participants Est. completion 2012-10 261 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00856986
The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 987 participants Est. completion 2010-11 233 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00857870
Insulin Glargine First Line vs Metformin in Type 2 Diabetic Subjects
Not yet reported GWT-TUD GmbH 96 participants Est. completion 2011-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00859898
Study of Dapagliflozin in Combination With Metformin XR to Initiate the Treatment of Type 2 Diabetes
Not yet reported AstraZeneca 1093 participants Est. completion 2010-05 123 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00860288
Efficacy and Long-Term Safety of Vildagliptin as Add-on Therapy to Metformin in Patients With Type 2 Diabetes
Not yet reported, Not yet reported Novartis Pharmaceuticals 1988 participants Est. completion 2011-03 187 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00864669
A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Non-fasting Conditions
Not yet reported Actavis Inc. 32 participants Est. completion 2002-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00864734
A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Non-fasting Conditions
Not yet reported Actavis Inc. 24 participants Est. completion 2002-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00865033
A Relative Bioavailability Study of Metformin HCL Tablets, 1000 mg Under Fasting Conditions
Not yet reported Sandoz 32 participants Est. completion 2005-11 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00865072
A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Fasting Conditions
Not yet reported Actavis Inc. 40 participants Est. completion 2003-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00865241
A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions
Not yet reported Actavis Inc. 36 participants Est. completion 2002-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00865436
A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions
Not yet reported Actavis Inc. 36 participants Est. completion 2004-04 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00865748
A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions
Not yet reported Actavis Inc. 40 participants Est. completion 2004-01 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00865839
A Relative Bioavailability Study of Metformin HCl 500 mg ER Tablets Under Fasting Conditions
Not yet reported Actavis Inc. 32 participants Est. completion 2002-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00865852
A Relative Bioavailability Study of Metformin HCl 750 mg ER Tablets Under Non-fasting Conditions
Not yet reported Actavis Inc. 40 participants Est. completion 2003-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT00868790
A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)
Not yet reported Merck Sharp & Dohme LLC 118 participants Est. completion 2010-07-13 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00870194
A Comparison of Adding Exenatide With Switching to Exenatide in Patients With Type 2 Diabetes Experiencing Inadequate Glycemic Control With Sitagliptin Plus Metformin
Not yet reported AstraZeneca 255 participants Est. completion 2010-04 36 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00871936
A Comparison of SLx-4090 in Combination With Metformin Versus Metformin Therapy Alone in Patients With Type 2 Diabetes
Not yet reported Response Pharmaceuticals 82 participants Est. completion 2009-10 12 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00875394
Study to Assess the Efficacy and Safety of Sitagliptin Added to the Regimen of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (0431-189)
Not yet reported Merck Sharp & Dohme LLC 68 participants Est. completion 2008-06-27 Stand-aloneOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00881530
Empagliflozin (BI 10773) in Type Two Diabetes (T2D) Patients, Open Label Extension
Not yet reported Boehringer Ingelheim 660 participants 137 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00881725
A Study of Pre-operative Metformin in Prostate Cancer
Not yet reported University Health Network, Toronto 24 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Status unknown NCT NCT00883259
Metformin and Gestational Diabetes in High-risk Patients: a RCTs
Not yet reported University Magna Graecia 80 participants 3 sites Stand-aloneOther conditions: Obesity, Polycystic Ovary Syndrome, Gestational DiabetesView official trial listing → -
Terminated NCT NCT00883766
Polycystic Ovary Syndrome (PCOS) and In Vitro Fertilization (IVF): A Comparison Between Standard Long Protocol Versus an Antagonist Protocol Starting on Day 1
Not yet reported Fundacion Dexeus 172 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, In Vitro FertilizationView official trial listing → -
Completed NCT NCT00885378
Efficacy and Safety Study of Saxagliptin + Metformin Immediate Release (IR) Versus Metformin IR Alone in Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 166 participants Est. completion 2010-02 41 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00889876
Effect of Exercise or Metformin on Nocturnal Blood Pressure and Other Risk Factors for CVD Among Obese Adolescents
Not yet reported Maria Sandberg Westerstahl 26 participants Est. completion 2015-12 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00892073
Hypothalamic Obesity Following Craniopharyngioma Surgery: A Pilot Trial of Combined Metformin and Diazoxide Therapy
Not yet reported The Hospital for Sick Children 9 participants Est. completion 2008-01 1 site Stand-aloneOther conditions: Hypothalamic ObesityView official trial listing → -
Completed NCT NCT00894322
A Study to Examine the Pharmacokinetics, Tolerability, Safety and Efficacy of Exenatide Once Weekly Suspension
Not yet reported, Not yet reported AstraZeneca 65 participants Est. completion 2009-08 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00897390
Bioequivalence Study of Saxagliptin and Glucophage Combination Formulations in Healthy Subjects (B)
Not yet reported AstraZeneca 24 participants Est. completion 2009-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00897884
Clinical and Biologic Effects of Metformin in Early Stage Breast Cancer
Not yet reported Mount Sinai Hospital, Canada 39 participants Est. completion 2011-07 2 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00899470
Bioequivalence Study of Saxagliptin and Glucophage Combination Formulations in Healthy Subjects (A)
Not yet reported AstraZeneca 24 participants Est. completion 2009-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT00900146
Dose Finding, Safety and Efficacy of Monthly Subcutaneous Canakinumab Administration in Metformin Monotherapy Treated Type 2 Diabetic Patients
Not yet reported, Not yet reported Novartis 556 participants Est. completion 2010-11 106 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00901979
A 12 Week Study in Patients With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Novartis Pharmaceuticals 693 participants Est. completion 2010-06 67 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00909480
Effect of Insulin Detemir and Insulin Glargine on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 457 participants Est. completion 2010-06 88 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00909506
Efficacy and Safety of Adjuvant Metformin for Operable Breast Cancer Patients
Not yet reported Seoul National University Hospital 105 participants Est. completion 2011-12 1 siteOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00909597
A Study of Taspoglutide Versus Pioglitazone in Patients With Type 2 Diabetes
Not yet reported Hoffmann-La Roche 756 participants Est. completion 2010-11 147 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00911313
Letrozole or Combined Metformin Clomiphene Citrate (CC) for Women With CC Resistant Polycystic Ovary Syndrome
Not yet reported Mansoura University 250 participants Est. completion 2009-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00913367
Efficacy/Safety Study of Amaryl®M 1/500 mg Twice Daily Versus Amaryl® 4 mg Both in Combination With Lantus® in Type 2 Diabetes Mellitus
Not yet reported Handok Inc. 110 participants Est. completion 2010-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00915772
Treatment of Type 2 Diabetes With Linagliptin 2.5 mg Bid + Metformin 500 or 1000 mg Bid and Metformin 1000 mg Bid
Not yet reported Boehringer Ingelheim 567 participants 112 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00918138
Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg
Not yet reported AstraZeneca 219 participants Est. completion 2010-05 21 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00922194
Metformin in Overweight Type 2 Diabetes Mellitus
Not yet reported Era's Lucknow Medical College 102 participants Est. completion 2008-12 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT00924534
A Safety PK/PD Study of SLV337 in Patients With Type 2 Diabetes
Not yet reported Abbott Products 61 participants Est. completion 2010-12 12 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00924573
Comparative Study of HOE490 O (Glimepiride and Metformin) Compared With Placebo on Top of Glimepiride
Not yet reported Sanofi 189 participants Est. completion 2010-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00929201
Sitagliptin/Metformin Fed Bioequivalence Study (0431A-080)
Not yet reported Merck Sharp & Dohme LLC 61 participants Est. completion 2008-05Type 2 diabetesView official trial listing → -
Completed NCT NCT00929539
Safety and Efficacy Study of JTT-130 in Obese Type 2 Diabetic Patients
Not yet reported Akros Pharma Inc. 496 participants Est. completion 2010-07 62 sitesOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT00930579
Pre-Surgical Study: Effect of Metformin on Breast Cancer Proliferation
Not yet reported Columbia University 35 participants Est. completion 2017-01-09 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00933309
The Impact of Obesity and Obesity Treatments on Breast Cancer
Not yet reported M.D. Anderson Cancer Center 25 participants Est. completion 2012-08 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00934323
Dose Proportionality Study About Amaryl M Slow Release (SR) 1/500 mg
Not yet reported Handok Inc. 33 participants Est. completion 2009-04 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00934570
Activity and Metformin Intervention in Obese Adolescents
Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 60 participants Est. completion 2012-05 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT00934817
Dose Proportionality Study Comparing Amaryl-M 1/500 mg and Amaryl-M 2/500 mg
Not yet reported Handok Inc. 36 participants Est. completion 2007-08Other conditions: HealthyView official trial listing → -
Status unknown NCT NCT00935805
Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy
Hospital de Clinicas de Porto Alegre 124 participants Est. completion 2012-07 1 siteOther conditions: Diabetes Mellitus, Arterial HypertensionView official trial listing → -
Completed NCT NCT00940472
Study on DMMET-01 Versus Metformin on Improvement of Metabolic Control in Naive Type 2 Diabetes Patients
Not yet reported, Not yet reported Laboratorios Silanes S.A. de C.V. 20 participants 1 siteOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT00940797
Effect of DMMET-01 on Insulin Sensitivity in Naive Type 2 Diabetes Patients (CLAMP)
Not yet reported Laboratorios Silanes S.A. de C.V. 20 participants 1 siteOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT00941148
Beta-Cell Function of Insulin Glargine Compared to Neutral Protamine Hagedorn (NPH) Insuline and to Insulin Detemir in Combination With Metformin
Not yet reported ikfe-CRO GmbH 30 participants Est. completion 2009-03 1 siteOther conditions: Type 2 Diabetic Patients, Insufficient Metabolic Control, OAD TreatmentView official trial listing → -
Completed NCT NCT00941161
Effect of Oral Combination Therapy in a Single Dosage Form in Patients With Type 2 Diabetes Mellitus
Not yet reported Laboratorios Silanes S.A. de C.V. 28 participants 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00941239
Tolerability and Pharmacokinetics of Metformin and Metformin Extended Release (ER)
Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2007-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT00941382
Sibutramine-metformin Combination Versus Sibutramine and Metformin Monotherapy in Obese Patients
Not yet reported Laboratorios Silanes S.A. de C.V. 60 participants Est. completion 2009-09 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT00942123
Study On the Role of Mitochondrial Dysfunction in the Pathogenesis of Metformin-associated Lactic Acidosis
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico 10 participants Est. completion 2011-10 1 siteOther conditions: Lactic Acidosis, MetforminView official trial listing → -
Completed NCT NCT00942188
A Study of LY2189102 in Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 106 participants Est. completion 2010-11 18 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00942318
Efficacy of Continuous Subcutaneous Insulin Infusion Versus Basal-bolus Multiple Daily Injections Regimen in Type 2 Diabetes
Not yet reported University Hospital, Toulouse 52 participants Est. completion 2013-02 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00944346
Study to Evaluate the Bioequivalence of a Test Tablet Formulation of Metformin HCl (1000 mg), Compared to an Equivalent Dose of a Commercially Available Reference Drug Product (Glucophage®, Bristol-Myers Squibb Company) in Fed, Healthy, Adult Subjects
Not yet reported Torrent Pharmaceuticals Limited 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT00947557
Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus (T2DM) on Background Therapy With Glimepiride With or Without Metformin
Not yet reported Forest Laboratories 677 participants 147 sitesOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Suspended NCT NCT00948324
Effect of Intensive Therapy Associated With CSII on β-cell Function With Newly Diagnosed Type 2 Diabetes
Not yet reported Sun Yat-sen University 400 participants Est. completion 2021-12Type 2 diabetesView official trial listing → -
Completed NCT NCT00948402
PED/PEA-15 Protein, PCOS, Obesity, Insulin Sensitivity Indexes, Metformin, Oral Contraceptives
Not yet reported Federico II University 20 participants Est. completion 2009-01 Stand-aloneOther conditions: Polycystic Ovarian Syndrome, Insulin SensitivityView official trial listing → -
Completed NCT NCT00951899
The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics
Not yet reported Mayo Clinic 38 participants Est. completion 2012-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00953355
Metformin and Folate Supplementation in Polycystic Ovary Syndrome (PCOS) Patients
Not yet reported University Magna Graecia 50 participants Est. completion 2007-05 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, AnovulationView official trial listing → -
Completed NCT NCT00959101
Comparison of Repaglinide and Metformin Combination Tablet Versus Repaglinide and Metformin as Separate Tablets in Healthy Volunteers
Not yet reported Novo Nordisk A/S 42 participants Est. completion 2009-10 1 site Stand-aloneOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT00960076
An 18 Week Efficacy and Safety Study of Saxagliptin and Metformin XR Combination in Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 282 participants Est. completion 2010-10 35 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00960661
A Trial Comparing Two Therapies: Basal Insulin/Glargine, Exenatide and Metformin Therapy (BET) or Basal Insulin/Glargine, Bolus Insulin Lispro and Metformin Therapy (BBT) in Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 1036 participants Est. completion 2012-08 95 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00961480
A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Co-administration of Sitagliptin and Metformin as Individual Tablets (0431A-095)
Not yet reported Merck Sharp & Dohme LLC 24 participants Est. completion 2007-11 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00961857
A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Concomitant Administration of Sitagliptin and Metformin as Individual Tablets (0431A-048)
Not yet reported Merck Sharp & Dohme LLC 48 participants Est. completion 2006-01-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00961909
A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus
Not yet reported Hoffmann-La Roche 122 participants Est. completion 2010-10 6 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00964184
Phenotypic and Genetic Correlates of Diabetes (Non-Type 1) in Young Non-Obese Asian Indians in North India and A Study to Evaluate the Efficacy of Sitagliptin (DPP-4 Inhibitor) in a Sub-group of the Study Population
Not yet reported Diabetes Foundation, India 133 participants Est. completion 2015-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00965549
Comparison of a Basal Plus One Insulin Regimen With a Biphasic Insulin Regimen in Type 2 Diabetes Patients
Not yet reported Sanofi 463 participants Est. completion 2012-12 74 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00965991
Metformin Compared to Glyburide in Gestational Diabetes
Not yet reported University of New Mexico 149 participants Est. completion 2023-08 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT00968812
CANagliflozin Treatment And Trial Analysis-Sulfonylurea (CANTATA-SU) SGLT2 Add-on to Metformin Versus Glimepiride
Not yet reported Janssen Research & Development, LLC 1452 participants Est. completion 2013-01 138 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00969566
Predictive Parameters for Efficacy of Sitagliptin and Metformin Combination
Not yet reported Seoul National University Bundang Hospital 150 participants Est. completion 2011-07 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00969631
Combined Metformin and Clomiphene Citrate (CC) or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome (PCOS)
Not yet reported Mansoura University 282 participants Est. completion 2009-02 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT00970528
Glucose Reduction by Early Acarbose Treatment in Basal Insulin
Not yet reported Bayer 124 participants Est. completion 2012-03 11 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00970593
Study Evaluating Safety, Tolerability, And Action Of OAP-189 In Subjects With Type 2 Diabetes On Metformin
Not yet reported Pfizer 92 participants Est. completion 2011-07-25 2 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00971243
Efficacy and Safety of MP-513 in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Tanabe Pharma Corporation 448 participants Est. completion 2011-04 44 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00971295
Effect of Eslicarbazepine Acetate on the Pharmacokinetics of Metformin in Healthy Volunteers
Not yet reported Bial - Portela C S.A. 20 participants Est. completion 2008-09 1 site Stand-aloneOther conditions: Neuropathic PainView official trial listing → -
Completed NCT NCT00971659
Adjunctive Therapy of Exenatide or Sitagliptin to Insulin Glargine in Type 2 Diabetes
Not yet reported Profil Institut für Stoffwechselforschung GmbH 48 participants Est. completion 2008-11 1 site MixedType 2 diabetesView official trial listing → -
Completed NCT NCT00972283
Comparison of NN1250 With Insulin Glargine Plus Insulin Aspart With/Without Metformin and With/Without Pioglitazone in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1006 participants Est. completion 2010-10-28 136 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00975052
A Study of the Effects of Sitagliptin (MK0431) and Metformin on Incretin Hormone Concentrations (0431-050)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 16 participants Est. completion 2006-03 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00975065
Galvus on Met Phase 4 Study : Study to Evaluate the Efficacy and Safety of Early Combination of Vildagliptin and Metformin in Patients With Type 2 Diabetes Mellitus
Not yet reported Handok Inc. 266 participants Est. completion 2012-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00976937
24-week Study Comparing Lixisenatide to Sitagliptin as add-on to Metformin in Obese Type 2 Diabetic Patients Younger Than 50 Years
Not yet reported Sanofi 319 participants Est. completion 2011-03 92 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT00978263
Comparison of Glargine and Oral Antidiabetic Drugs (OADs) in Newly Diagnosed Type 2 Diabetes
Not yet reported Chongqing Medical University 47 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Terminated NCT NCT00984490
Metformin Hydrochloride in Treating Women With Stage I or Stage II Breast Cancer That Can Be Removed By Surgery
Not yet reported Vanderbilt-Ingram Cancer Center 5 participants Est. completion 2011-07 3 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00984867
Dapagliflozin DPPIV Inhibitor add-on Study
Not yet reported AstraZeneca 833 participants Est. completion 2011-09 88 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00986401
Safety and Tolerability of Trospium Chloride and Metformin Hydrochloride in Healthy Subjects
Not yet reported Allergan 44 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT00988078
Effects of Metformin and Oral Hormonal Contraceptive in Adolescents With Polycystic Ovary Syndrome
Not yet reported Federal University of São Paulo 90 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Suspended NCT NCT00990444
A Two Part Study of Peroral Insulin in Type 2 Diabetes
Not yet reported, Not yet reported Bows Pharmaceuticals AG 32 participants Est. completion 2010-12 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT00991055
Comparison of the Efficacy and Safety Between Pioglitazone and Placebo Added to Combination Therapy in Type 2 Diabetes
Not yet reported National Cheng-Kung University Hospital 40 participants Est. completion 2010-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00993187
Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)
Not yet reported Merck Sharp & Dohme LLC 292 participants Est. completion 2013-10-29 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00994812
The Effects of Metformin on Pregnancy and Miscarriage Rates in Polycystic Ovary Syndrome (PCOS)
Not yet reported University of Oulu 326 participants Est. completion 2009-12 5 sites Stand-aloneOther conditions: Polycystic Ovary Syndrome, Miscarriage, Infertility, Toxemia, Gestational DiabetesView official trial listing → -
Completed NCT NCT00995345
Safety and Efficacy of Once-Daily KRP-104 in Type 2 Diabetics With Inadequate Glycemic Control on Metformin Alone
Not yet reported ActivX Biosciences, Inc. 403 participants Est. completion 2011-01 45 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT00995787
Safety and Tolerability of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients Treated With Metformin and Sulfonylurea
Not yet reported AstraZeneca 75 participants Est. completion 2010-02 1 siteOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT00996658
Linagliptin Versus Placebo in Type 2 Diabetic Patients With Inadequate Glycaemic Control on Metformin in Combination With Pioglitazone
Not yet reported Boehringer Ingelheim 278 participants 52 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00997152
Efficacy and Safety Study of JTT-654 in Type 2 Diabetic Patients
Not yet reported Akros Pharma Inc. 152 participants Est. completion 2010-04 42 sitesOther conditions: Type II Diabetes MellitusView official trial listing → -
Terminated NCT NCT00998686
Safety and Efficacy Study of Dutogliptin in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin
Not yet reported Phenomix 650 participants Est. completion 2011-11 44 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01001962
Double Blind Placebo Study of JARDIANCE® (Empagliflozin) in Prehypertensives Type II Diabetics
Not yet reported Aristotle University Of Thessaloniki 1054 participants Est. completion 2020-01 1 siteOther conditions: Hypertension, Type II DiabetesView official trial listing → -
Completed NCT NCT01002807
Bioavailability Study of Fixed Dose Combination (FDC) Formulations of Dapagliflozin and Metformin XR Versus Individual Component Coadministered to Healthy Subjects in a Fasted State
Not yet reported AstraZeneca 15 participants Est. completion 2010-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01003184
Efficacy of Once-Weekly Exenatide Versus Once or Twice Daily Insulin Detemir in Patients With Type 2 Diabetes
Not yet reported AstraZeneca 222 participants Est. completion 2011-12 34 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01003483
Metformin Versus Orlistat in Obese Polycystic Ovary Syndrome (PCOS) Patients
Not yet reported Yazd Research & Clinical Center for Infertility 80 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT01005160
Drug Interaction Between CKD-501 and Metformin
Not yet reported Chong Kun Dang Pharmaceutical 24 participants Est. completion 2010-02 Stand-aloneOther conditions: Healthy Male VolunteersView official trial listing → -
Completed NCT NCT01006590
Efficacy and Tolerability of Saxagliptin add-on Compared to Uptitration of Metformin in Patients With Type 2 Diabetes
Not yet reported AstraZeneca 286 participants Est. completion 2010-12 51 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01006603
Saxagliptin Compared to Glimepiride in Elderly Type 2 Diabetes Patients, With Inadequate Glycemic Control on Metformin
Not yet reported AstraZeneca 957 participants Est. completion 2012-06 131 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01008046
N-acetyl Cysteine and Clomiphene Citrate or Metformin and Clomiphene Citrate for Women With CC Resistant Polycystic Ovary Syndrome (PCOS).
Not yet reported Mansoura University 192 participants Est. completion 2009-06 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01009580
Comparison of NN5401 With Biphasic Insulin Aspart 30 in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 447 participants Est. completion 2010-08-23 53 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01011868
Efficacy and Safety of BI 10773 in Combination With Insulin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 494 participants 99 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01012037
Linagliptin 2.5 mg Twice Daily Versus 5 mg Once Daily as add-on Therapy to Twice Daily Metformin in Type 2 Diabetes
Not yet reported Boehringer Ingelheim 491 participants 84 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01013051
Effect of Gastric Bypass on the Absorption of Metformin
University of Alberta 34 participants Est. completion 2010-12 1 siteOther conditions: Obesity, Gastric BypassView official trial listing → -
Completed NCT NCT01017302
A Study With RO5095932 in Patients With Type 2 Diabetes on Stable Metformin Therapy.
Not yet reported Hoffmann-La Roche 32 participants Est. completion 2011-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01020123
Evaluate Efficacy, Safety and Tolerability of AZD1656 as Add-on Treatment to Metformin in Type 2 Diabetes Mellitus (TD2M) Patients
Not yet reported AstraZeneca 530 participants Est. completion 2011-02 77 sitesOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT01021579
Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
Not yet reported Fasa University of Medical Sciences 84 participants Est. completion 2009-11 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01022658
INSUlin Regimens and VASCular Functions
Not yet reported Assistance Publique - Hôpitaux de Paris 42 participants Est. completion 2011-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01023581
Efficacy and Safety of Alogliptin Plus Metformin in Patients With Type 2 Diabetes
Not yet reported Takeda 784 participants Est. completion 2011-06 201 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01024244
A Study of LY2599506 in Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 78 participants Est. completion 2010-07 16 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01025765
The Effects of Oral Hypoglycemic Agents on Chronic Hepatitis C Patients Receiving Peg-Intron Plus Ribavirin
Not yet reported National Taiwan University Hospital 80 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT01028391
30-Week Extension to an Initial Combination Study (24 Weeks in Duration) of Sitagliptin With Pioglitazone (0431-064)
Not yet reported Merck Sharp & Dohme LLC 317 participants Est. completion 2009-01-01 Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01029795
A Study of LY2599506 (Oral Agent Medication: Glucokinase Activator 1) in Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 38 participants Est. completion 2010-06 16 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01033773
Stop Emergency Room Visits for Hyperglycemia Project - District of Columbia (DC)
Not yet reported Medstar Health Research Institute 86 participants Est. completion 2009-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01034111
A Local Experiential Study With Sitagliptin (an Antihyperglycemic Drug) in 30 Patients With Type 2 Diabetes Mellitus (0431-178)
Not yet reported Merck Sharp & Dohme LLC 30 participants Est. completion 2010-10-04 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01035528
Can Insulin Glargine Improve Myocardial Function in Patients With T2D and Coronary Artery Disease (CAD)
Not yet reported Munich Municipal Hospital 32 participants Est. completion 2010-08 1 siteCardiovascular diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT01037660
Effects of Lipemia and Metformin on Endothelial Function
Not yet reported Boston University 139 participants Est. completion 2016-12-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01037842
Effect of Combination of Mitiglinide and Metformin on Glycemic Control in Patients With Type 2 Diabetes Mellitus
Not yet reported Seoul National University Hospital 145 participants Est. completion 2008-05 13 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01043965
Myocardial Perfusion in Type 2 Diabetes
Not yet reported, Not yet reported University of Sao Paulo General Hospital 61 participants Est. completion 2009-08Type 2 diabetesView official trial listing → -
Completed NCT NCT01045707
Comparison of NN5401 Versus Insulin Glargine, Both Combined With Metformin Treatment, in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 530 participants Est. completion 2010-10 92 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01046032
Metformin Treatment Before in Vitro Fertilization (IVF) in Women With Ultrasound Evidence of Polycystic Ovaries
Not yet reported University of Oxford 134 participants Est. completion 2009-05 3 sitesOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01046422
Safety Study of BMS-770767 in Subjects With Type 2 Diabetes
Not yet reported Bristol-Myers Squibb 76 participants Est. completion 2011-01 18 sites Stand-aloneOther conditions: Diabetes Type 2View official trial listing → -
Status unknown NCT NCT01046500
Myo-inositol Versus Metformin Administration in Post-menopausal Women With Metabolic Syndrome
Not yet reported University of Messina 100 participants Est. completion 2014-12 1 siteMetabolic syndromeView official trial listing → -
Terminated NCT NCT01051011
A Study to Compare Taspoglutide and Insulin Glargine in Insulin-Naïve Patients With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin and Sulfonylurea Combination Therapy
Not yet reported Hoffmann-La Roche 370 participants Est. completion 2010-12 56 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01055691
A Study Comparing the Amount of Metformin and After Taking a Combination Tablet vs. Separate Tablets
Not yet reported AstraZeneca 120 participants Est. completion 2010-04 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT01059825
Study Of Safety And Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes (MK-8835-016)
Not yet reported Merck Sharp & Dohme LLC 375 participants Est. completion 2011-01-20 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01064687
A Study in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 978 participants Est. completion 2012-05 89 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01065298
Efficacy Of Autologous Bone Marrow Derived Stem Cell Transplantation In Patients With Type 2 Diabetes Mellitus-2
Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2011-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01065766
Sitagliptin/Metformin (JANUMET) Re-examination Study (0431A-182)
Merck Sharp & Dohme LLC 4065 participants Est. completion 2013-05Type 2 diabetesView official trial listing → -
Completed NCT NCT01066715
Safety and Efficacy of XOMA 052 in Subjects With Type 2 Diabetes Mellitus on Stable Metformin Monotherapy
Not yet reported XOMA (US) LLC 421 participants Est. completion 2011-07 67 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01068652
Effect of Different Insulin Administrations, All in Combination With Metformin, on Glycaemic Control in Subjects With Type 2 Diabetes Inadequately Controlled by Oral Anti-diabetic Drugs
Not yet reported Novo Nordisk A/S 403 participants Est. completion 2012-05 19 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01068717
Bioequivalence Study of 2.5-mg Saxagliptin and 500-mg Glucophage in Tablets and a Fixed-dose Combination Tablet in Healthy Participants
Not yet reported AstraZeneca 27 participants Est. completion 2010-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01068730
Bioequivalence Study of 500 mg and 1000 mg Glucophage (Metformin) Tablets in Healthy Subjects
Not yet reported AstraZeneca 28 participants Est. completion 2010-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01068743
Bioequivalence Study of Fixed Dose Combination of 2.5 mg Saxagliptin/850 mg Metformin Tablet Relative to 2.5 mg Onglyza and 850 mg Glucophage Tablets Co-Administered
Not yet reported AstraZeneca 24 participants Est. completion 2010-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01068860
To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies
Not yet reported Novartis 246 participants Est. completion 2010-08 52 sites Stand-aloneType 2 diabetesPrediabetesView official trial listing → -
Terminated NCT NCT01069965
Safety and Efficacy of BGP-15 in Patients With Type 2 Diabetes Mellitus
Not yet reported N-Gene Research Laboratories, Inc. 196 participants Est. completion 2011-10 30 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01070160
Endometrial Effects of Metformin Action in Women With Polycystic Ovarian Syndrome (PCOS)
Yale University 14 participants Est. completion 2013-07 1 siteOther conditions: Polycystic Ovarian SyndromeView official trial listing → -
Completed NCT NCT01071850
A Study to Evaluate the Effect of ASP1941 in Adult Patients With Type 2 Diabetes Mellitus
Not yet reported Astellas Pharma Inc 412 participants Est. completion 2011-04-11 59 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01075282
A Study in Participants With Type 2 Diabetes Mellitus (AWARD-2)
Not yet reported Eli Lilly and Company 810 participants Est. completion 2012-11 78 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01076075
A Study to Evaluate the Safety and Efficacy of Sitagliptin 100 mg in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control (MK-0431-229)
Not yet reported Merck Sharp & Dohme LLC 427 participants Est. completion 2012-01-19 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01076088
Safety and Efficacy of Co-Administration of Sitagliptin and Metformin in China (MK-0431-121)
Not yet reported Merck Sharp & Dohme LLC 744 participants Est. completion 2012-12-24 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01077323
A Retrospective Cohort Study of Acute Pancreatitis in Relation to Use of Exenatide and Other Antidiabetic Agents
AstraZeneca 363766 participants Est. completion 2008-03 1 siteType 2 diabetes Other conditions: Healthy Subjects (Treated With no Diabetes Therapies)View official trial listing → -
Completed NCT NCT01077479
Metformin in Preventing Androgen Deprivation Therapy Induced Insulin Resistance and Metabolic Syndrome
Not yet reported Western Sydney Local Health District 28 participants Est. completion 2013-06 1 site Stand-aloneMetabolic syndrome Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01082120
Investigate the Effect of AZD1656 on the Pharmacokinetics of Pioglitazone and Vice Versa in Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 28 participants Est. completion 2010-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01083212
To Evaluate the Effect of Gemfibrozil on the Pharmacokinetics and Pharmacodynamics of a Single Dose of AZD1656
Not yet reported AstraZeneca 19 participants Est. completion 2010-06 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01084005
Efficacy and Safety of Linagliptin in Elderly Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 241 participants 34 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01084486
Effect of Treatment With Insulin Sensitizer on Arterial Properties, Metabolic Parameters and Liver Function in Patients With Nonalcoholic Fatty Liver Disease
Not yet reported, Not yet reported Wolfson Medical Center 1 site Stand-aloneMASLDView official trial listing → -
Completed NCT NCT01087567
INSPIRE Diabetes Study: Basal Bolus Insulin as Primary Treatment of Type 2 Diabetes
Not yet reported Ohio University 23 participants Est. completion 2014-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01087866
Metformin Versus Insulin in the Treatment of Gestational Diabetes Mellitus
Not yet reported, Not yet reported University of Oulu 97 participants Est. completion 2009-10 1 site Stand-aloneOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT01087983
Lapatinib With Sirolimus or Metformin
Not yet reported M.D. Anderson Cancer Center 111 participants Est. completion 2015-09 1 site Stand-aloneOther conditions: Advanced CancersView official trial listing → -
Completed NCT NCT01089166
Study to Compare the Bioavailability of Extended Release Metformin HCl Tablet Versus Glucophage XR® Tablets in Healthy Human Volunteers Under Fasting Condition
Not yet reported Torrent Pharmaceuticals Limited 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01089179
Bioequivalence Study of Metformin Hydrochloride Extended Release 500 mg Tablet Versus Glucophage XR® 500 mg Tablet in Healthy Volunteers Under Fed Conditions
Not yet reported Torrent Pharmaceuticals Limited 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01089192
Bioequivalence Study of Metformin Hydrochloride Extended Release 750 mg Tablets Versus Glucophage XR® 750 mg Tablet in Healthy Volunteers Under Fasting Conditions.
Not yet reported Torrent Pharmaceuticals Limited 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01089205
Bioequivalence Study of Metformin Hydrochloride Extended Release 750 mg Tablets Versus Glucophage XR® 750 mg Tablet in Healthy Volunteers Under Fed Conditions.
Not yet reported Torrent Pharmaceuticals Limited Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01089790
Safety and Efficacy of Dutogliptin in Patients With Type 2 Diabetes Mellitus Receiving Background Treatment With Glimepiride Alone or in Combination With Metformin or With Pioglitazone Alone
Not yet reported Forest Laboratories 141 participants 149 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01093794
Bioequivalence Study of Sitagliptin/Metformin Combination Tablet (MK0431A-122)
Not yet reported Merck Sharp & Dohme LLC 28 participants Est. completion 2010-06 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01095653
A Phase III Study of BMS-512148 (Dapagliflozin) in Asian Patients With Type 2 Diabetes Who Are Not Well Controlled With Diet and Exercise
Not yet reported AstraZeneca 1179 participants Est. completion 2012-03 39 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01095666
A Phase III Study of BMS-512148 (Dapagliflozin) in Asian Patients With Type 2 Diabetes Who Are Not Well Controlled on Metformin Alone
Not yet reported AstraZeneca 1484 participants Est. completion 2013-03 33 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01095822
Effects of Valsartan and Aliskiren on Hemostatic Indices in Hypertensive Diabetics
Not yet reported HeartDrug Research LLC 50 participants Est. completion 2011-03 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01095991
Investigate the Effect of AZD1656 on the Pharmacokinetics of Sitagliptin in Patients With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 12 participants Est. completion 2010-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01096940
Study To Assess the Pharmacokinetics of AZD1656 During Coadministration With Simvastatin
Not yet reported AstraZeneca 44 participants Est. completion 2010-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01099137
Effect of Vildagliptin in Type 2 Diabetes Treated With Sulphonylurea and Metformin
Not yet reported Seoul National University Bundang Hospital 344 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01099618
Ketosis-Prone Diabetes Mellitus (KPDM): Metformin Versus Sitagliptin Treatment
Not yet reported Dawn Smiley MD 48 participants Est. completion 2014-08 1 siteOther conditions: Ketosis Prone Diabetes, Diabetes Ketoacidosis, HyperglycemiaView official trial listing → -
Status unknown NCT NCT01101204
The Effects of Hypolipemic and Antidiabetic Treatment on Cytokines
Not yet reported Medical University of Silesia 200 participants Est. completion 2012-12 1 siteOther conditions: Diabetes, Dyslipidemia, Inflammation, CytokinesView official trial listing → -
Completed NCT NCT01101438
A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer
Not yet reported Canadian Cancer Trials Group 3649 participants Est. completion 2023-08-18 344 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01103609
Investigate the Effect of AZD1656 on the Pharmacokinetics and Pharmacodynamics of Warfarin in Type 2 Diabetes Mellitus (T2DM) Patients
Not yet reported AstraZeneca 16 participants Est. completion 2010-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01103622
Investigate the Effect of AZD1656 on the Pharmacokinetics of Digoxin in Type 2 Diabetes Mellitus Patients
Not yet reported AstraZeneca 20 participants Est. completion 2010-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01105429
Single Ascending Dose Study of BMS-820132 in Patients With Type 2 Diabetes
Not yet reported Bristol-Myers Squibb 56 participants Est. completion 2010-10 3 sitesOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT01106131
Efficacy and Safety of CKD-501 Versus Pioglitazone When Added to Metformin
Not yet reported Chong Kun Dang Pharmaceutical 253 participants Est. completion 2012-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01106625
The CANTATA-MSU Trial (CANagliflozin Treatment And Trial Analysis - Metformin and SUlphonylurea)
Not yet reported Janssen Research & Development, LLC 469 participants Est. completion 2012-04 76 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01106651
A Safety and Efficacy Study of Canagliflozin in Older Patients (55 to 80 Years of Age) With Type 2 Diabetes Mellitus
Not yet reported Janssen Research & Development, LLC 716 participants Est. completion 2013-05 86 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01106677
The CANTATA-D Trial (CANagliflozin Treatment and Trial Analysis - DPP-4 Inhibitor Comparator Trial)
Not yet reported Janssen Research & Development, LLC 1284 participants Est. completion 2012-05 125 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01106690
The CANTATA-MP Trial (CANagliflozin Treatment and Trial Analysis - Metformin and Pioglitazone)
Not yet reported Janssen Research & Development, LLC 344 participants Est. completion 2012-07 83 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01107717
Durability of Combination Therapy With Exenatide/Pioglitazone/Metformin vs. Conventional Therapy in New Onset T2DM
Not yet reported The University of Texas Health Science Center at San Antonio 318 participants Est. completion 2023-02-03 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Withdrawn NCT NCT01107808
Calcium, Vitamin D and Metformin to Treat Insulin Resistance in Obese African American Adolescent Females
Not yet reported University of Alabama at Birmingham Est. completion 2011-03 Stand-aloneOther conditions: Insulin Resistance, Insulin Sensitivity, Obesity, Vitamin D DeficiencyView official trial listing → -
Completed NCT NCT01111955
Safety Study of BMS-823778 in Subjects With Type 2 Diabetes
Not yet reported Bristol-Myers Squibb 62 participants Est. completion 2011-01 14 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01115140
Metformin and Folate in Pregnant Polycystic Ovary Syndrome(PCOS) Women
Not yet reported University Magna Graecia 50 participants Est. completion 2011-05 1 site Stand-aloneOther conditions: Pregnancy, Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01117103
A Prospective, Observational Study to Assess and Evaluate the Use of Glucophage XR Therapy in the Management of Patients With Type 2 Diabetes
Merck KGaA, Darmstadt, Germany 3592 participants Est. completion 2009-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01117350
Efficacy Assessment of Insulin Glargine Versus LiraglutidE After Oral Agents Failure
Not yet reported Sanofi 978 participants Est. completion 2013-03 136 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01117584
A Study to Evaluate the Effect of ASP1941 in Combination With Metformin in Adult Patients With Type 2 Diabetes Mellitus
Not yet reported Astellas Pharma Inc 343 participants Est. completion 2011-04-01 44 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01119846
A Study in Type 2 Diabetics of Single and Multiple Doses of Orally Administered GSK1292263 to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics
Not yet reported GlaxoSmithKline 100 participants Est. completion 2010-03-19 7 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01123980
Comparison of the Blood Sugar Lowering Effect of Biphasic Insulin Aspart 30 and Insulin Glargine Both Combined With Metformin and Glimepiride in Chinese and Japanese Subjects With Type 2 Diabetes New to Insulin Treatment
Not yet reported Novo Nordisk A/S 521 participants Est. completion 2011-06 34 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01125150
Spectroscopic and Colorimetric Analysis of Acanthosis Nigricans in Patients With Hyperinsulinemia
Henry Ford Health System 9 participants Est. completion 2012-06 1 siteOther conditions: Acanthosis Nigricans, Hyperinsulinemia, Spectroscopic AnalysisView official trial listing → -
Completed NCT NCT01126580
A Study in Participants With Type 2 Diabetes Mellitus (AWARD-3)
Not yet reported Eli Lilly and Company 807 participants Est. completion 2012-06 91 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01128621
A Study in Type 2 Diabetic Subjects on Stable Metformin Therapy to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Co-administering Single and Multiple Oral Doses of GSK1292263
Not yet reported GlaxoSmithKline 66 participants Est. completion 2010-04-12 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01131182
Study of Sitagliptin Treatment in Patients With Type 2 Diabetes During Ramadan (0431-263)
Not yet reported Merck Sharp & Dohme LLC 1147 participants Est. completion 2010-11-04 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01135433
A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Metformin in Type 2 Diabetic Patients
Not yet reported Astellas Pharma Inc 168 participants Est. completion 2011-11-28 7 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01136512
Metformin Use and Vitamin B12 Deficiency
Northwell Health 89 participants Est. completion 2008-12 1 siteType 2 diabetes Other conditions: Vitamin B12 DeficiencyView official trial listing → -
Completed NCT NCT01137812
The CANTATA-D2 Trial (CANagliflozin Treatment And Trial Analysis - DPP-4 Inhibitor Second Comparator Trial)
Not yet reported Janssen Research & Development, LLC 756 participants Est. completion 2012-03 184 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01140438
Treatment of Latent Autoimmune Diabetes of the Adult
Not yet reported Norwegian University of Science and Technology 64 participants Est. completion 2018-11 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01144728
Initiation and Titration of Amaryl
Not yet reported Sanofi 172 participants Est. completion 2010-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01144975
Study of the Safety and Biologic Activity of XOMA 052 in Subjects With Type 2 Diabetes Mellitus
Not yet reported XOMA (US) LLC 76 participants Est. completion 2011-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01154348
Study to Assess Safety and Pharmacokinetics of Double-Blind S-707106 Alone and in Combination With Open-Label Metformin in Patients With Type 2 Diabetes Mellitus
Not yet reported Shionogi 34 participants Est. completion 2010-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01156246
Study to Assess the Effect of Food on Combination Dapagliflozin/Metformin Tablet in Healthy Volunteers
Not yet reported AstraZeneca 18 participants Est. completion 2010-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01156597
Effects of Pioglitazone on High-density Lipoprotein (HDL) Function in Persons With Diabetes
Not yet reported University of Miami 30 participants Est. completion 2010-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01159600
Efficacy and Safety Study With Empagliflozin (BI 10773) vs. Placebo as add-on to Metformin or Metformin Plus Sulfonylurea Over 24 Weeks in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 1504 participants 148 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01160042
Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fasting Condition
Not yet reported Dr. Reddy's Laboratories Limited 54 participants Est. completion 2005-04 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01160068
Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fed Condition
Not yet reported Dr. Reddy's Laboratories Limited 50 participants Est. completion 2005-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01162772
Influence of DPP-4 on Inflammatory Parameters in Diabetics: Gender Aspects
Medical University of Vienna 80 participants 1 siteType 2 diabetes Other conditions: Cardiovascular Risk, Endothelial DysfunctionView official trial listing → -
Terminated NCT NCT01167738
Combination Chemotherapy With or Without Metformin Hydrochloride in Treating Patients With Metastatic Pancreatic Cancer
Not yet reported IRCCS San Raffaele 60 participants Est. completion 2015-04 1 site Stand-aloneOther conditions: Pancreatic CancerView official trial listing → -
Completed NCT NCT01169090
A Study Comparing the Safety, Tolerance, and Efficacy of Various Doses of SK-0403 Versus Placebo and Sitagliptin 100 mg in Patients Not Well-Controlled on Metformin Therapy
Not yet reported Kowa Research Institute, Inc. 620 participants Est. completion 2011-08 40 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01169779
Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled by Metformin
Not yet reported Sanofi 391 participants Est. completion 2011-12 35 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Withdrawn NCT NCT01171456
Early Intervention for Gestational Diabetes
Not yet reported Intermountain Health Care, Inc. Est. completion 2010-07 1 siteOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT01175473
Effects of Lixisenatide Compared to Liraglutide on the Postprandial Plasma Glucose in Patients With Type 2 Diabetes
Not yet reported Sanofi 148 participants Est. completion 2010-11 7 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01175824
Comparison of the Efficacy and Safety of Two Insulin Intensification Strategies
Not yet reported Eli Lilly and Company 478 participants Est. completion 2012-11 18 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT01177709
Metformin for Weight Loss in Schizophrenia
Not yet reported Nathan Kline Institute for Psychiatric Research 12 participants Est. completion 2011-04 1 site Stand-aloneOther conditions: Schizophrenia, ObesityView official trial listing → -
Completed NCT NCT01181674
Remission Evaluation of Metabolic Interventions in Type 2 Diabetes (REMIT Pilot Trial)
Not yet reported Population Health Research Institute 83 participants Est. completion 2015-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01187849
Metformin to Prevent Metabolic Complications in Glucocorticoid Excess
Not yet reported University Hospital, Basel, Switzerland 29 participants Est. completion 2015-12 1 siteOther conditions: Patients With Glucocorticoid TreatmentView official trial listing → -
Completed NCT NCT01192139
Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin XR Tablet (Manufactured in Mt Vernon, IN) Relative to 5 mg Saxagliptin Tablet and 500 mg Metformin XR Tablet (Manufactured in Evansville, IN)
Not yet reported AstraZeneca 30 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01192152
Bioequivalence Study of the Fixed Dose Combination of 5 mg Saxagliptin/1000 mg Metformin XR (Manufactured in Mt Vernon, IN) Relative to 5 mg of Onglyza and 2 × 500 mg Glucophage XR
Not yet reported AstraZeneca 30 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01193296
Glycemic Holter Study (Continuous Glucose Monitoring) -
Not yet reported Novartis 36 participants Est. completion 2011-06 7 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01195090
Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and Sulfonylurea
Not yet reported Sung-Chen Liu 120 participants Est. completion 2012-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01195259
Malignancy Meta Analysis for BRL49653
GlaxoSmithKline 1 participants Est. completion 2010-01Type 2 diabetesView official trial listing → -
Completed NCT NCT01196546
Efficacy and Safety of Combination Therapy of Vildagliptin/Metformin in Patients in Type 2 Diabetes Mellitus (T2DM)
Not yet reported Novartis 161 participants Est. completion 2011-10 8 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01203111
Intensive Insulin Glulisine Therapy in Patients With Type 2 Diabetes Inadequately Controlled With Basal Insulin and Oral Glucose-lowering Drugs
Not yet reported Sanofi 207 participants Est. completion 2012-07 10 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01204294
Comprehensive Add on Study in Japan
Not yet reported Boehringer Ingelheim 574 participants Est. completion 2012-01 43 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01204580
ADIponectin and Asymmetric Dimethylarginine (ADMA) Level in Type-2 Diabetes Patients After 12 Weeks of Treatment With GlimepiRide And Metformin Fixed Dose Combination
Not yet reported Sanofi 40 participants Est. completion 2012-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01204775
Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin as Monotherapy in Pediatric Patients With Type 2 Diabetes
Not yet reported AstraZeneca 26 participants Est. completion 2016-04 16 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01205672
Evaluation of the Molecular Effects of Metformin on the Endometrium in Patients With Endometrial Cancer
Not yet reported M.D. Anderson Cancer Center 21 participants Est. completion 2017-05-28 2 sites Stand-aloneOther conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT01206153
Metformin for Treatment Antipsychotic Induced Amenorrhea in Female Schizophrenic Patients
Not yet reported Central South University 84 participants Est. completion 2010-03 1 site Stand-aloneOther conditions: AmenorrheaView official trial listing → -
Status unknown NCT NCT01206647
Investigation of a Switch From Insulin Therapy to a Metformin & Saxagliptin Combination in Patients With Type 2 Diabetes Mellitus
Not yet reported ikfe-CRO GmbH 120 participants Est. completion 2011-02 7 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01206712
Beta Cell Relieving and Cardiovascular Protective Effects of LANTUS Treatment in Type 2 Diabetes Patients
ikfe-CRO GmbH 106 participants Est. completion 2010-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01208012
Impact of Liraglutide on Endothelial Function and Microvascular Blood Flow in Type 2 Diabetes Mellitus
Not yet reported ikfe-CRO GmbH 44 participants Est. completion 2010-11 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Terminated NCT NCT01208740
Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization
Not yet reported University Magna Graecia 88 participants Est. completion 2011-03 1 site Stand-aloneOther conditions: Infertility, PCOS, Prognosis for Poor ResponseView official trial listing → -
Completed NCT NCT01210001
Efficacy and Safety of Empagliflozin (BI 10773) in Type 2 Diabetes Patients on a Background of Pioglitazone Alone or With Metformin
Not yet reported Boehringer Ingelheim 499 participants 68 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01210911
Metformin Combined With Chemotherapy for Pancreatic Cancer
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 120 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Locally Advanced Pancreatic Cancer, Metastatic Pancreatic CancerView official trial listing → -
Completed NCT NCT01211197
Bioavailability of a Fixed Dose Combination Tablet With Empagliflozin (BI 10773) and Metformin Compared With the Monocomponents and Effect of Food on Bioavailability
Not yet reported Boehringer Ingelheim 16 participants 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01213563
Management of Type 2 Diabetes After Gastric Bypass Surgery
Not yet reported Imperial College London 50 participants Est. completion 2010-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01215032
Metformin in Castration-Resistant Prostate Cancer
Not yet reported Massachusetts General Hospital 21 participants Est. completion 2015-01 3 sites Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT01215097
Efficacy and Safety Study of Linagliptin (5 mg Administered Orally Once Daily) Over 24 Weeks in Type 2 Diabetic Patients With Insufficient Glycaemic Control Despite Metformin Therapy
Not yet reported Boehringer Ingelheim 306 participants Est. completion 2012-04 19 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01215331
Gestational Diabetes: Insulin or Oral Hypoglycemic Agents?
Not yet reported Université de Sherbrooke 73 participants Est. completion 2016-05 1 site Stand-aloneOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT01216397
Relative Bioavailability of Two Different Batches of a Linagliptin / Metformin Combination Tablet in Healthy Volunteers
Not yet reported Boehringer Ingelheim 40 participants 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01217073
A Dose-Range Finding Study in Participants With Type 2 Diabetes (MK-3102-006)
Not yet reported Merck Sharp & Dohme LLC 685 participants Est. completion 2013-04-01Type 2 diabetesView official trial listing → -
Completed NCT NCT01217307
Metformin to Reduce Heart Failure After Myocardial Infarction
Not yet reported, Not yet reported University Medical Center Groningen 380 participants Est. completion 2015-10 1 site Stand-aloneCardiovascular diseaseHeart failure Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01217892
Evaluation of Dapagliflozin Taken Twice-daily
Not yet reported AstraZeneca 400 participants Est. completion 2011-08 55 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01219582
GLucobay M OBservation Study for Efficacy and Safety in Treatment of Type-2 Diabetes Patients
Bayer 9364 participants Est. completion 2012-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01221519
A Relative Bioavailability Study Measuring the Extent and Rate of Absorption of Different Tablet Formulations of AZD1656 in Type 2 Diabetes Mellitus (T2DM) Patients
Not yet reported AstraZeneca 20 participants Est. completion 2011-01 1 siteType 2 diabetes Other conditions: High Blood SugarView official trial listing → -
Completed NCT NCT01224366
Efficacy and Safety of Vildagliptin as add-on Therapy to Insulin in Patients With Type 2 Diabetes Mellitus
Not yet reported Novartis 448 participants Est. completion 2011-10 66 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01228240
The Efficacy of Metformin Produced by Pars Mino Co in Comparison With Canadian Apotex Co.
Not yet reported Zanjan University of Medical Sciences 18 participants Est. completion 2009-09 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01231074
Reducing Antipsychotic-Induced Weight Gain in Children With Metformin
Not yet reported Nationwide Children's Hospital 96 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Obesity, Weight Gain, Psychotropic Induced Weight GainView official trial listing → -
Completed NCT NCT01232036
Clinical Trial to Compare the Pharmacokinetics and Pharmacodynamics After Oral Administration of Glucophage and HL-018
Not yet reported Asan Medical Center 28 participants Est. completion 2010-10 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01232491
Impact of Dietary Intervention on Weight Change in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 611 participants Est. completion 2011-11-14 112 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01232946
Cooperation of Insulin and GLP-1 on Myocardial Glucose Uptake
Not yet reported Indiana University 30 participants Est. completion 2017-09-08 1 site MixedType 2 diabetesView official trial listing → -
Completed NCT NCT01233206
Metformin in High Responder Polycystic Ovary Syndrome (PCOS) Patients Undergoing IVF Cycles
Not yet reported University Magna Graecia 120 participants Est. completion 2011-01 1 site Stand-aloneOther conditions: Infertility, Polycystic Ovary Syndrome (PCOS)View official trial listing → -
Completed NCT NCT01233622
Safety and Efficacy of Galvus as add-on Therapy to Metformin Plus Glimepiride
Not yet reported Novartis 317 participants Est. completion 2011-11 55 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01234649
Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
Not yet reported Woman's 153 participants Est. completion 2019-06-14 1 site Stand-aloneType 2 diabetesMetabolic syndromePrediabetes Other conditions: Gestational Diabetes Mellitus, Disorder of Glucose RegulationView official trial listing → -
Completed NCT NCT01237314
The Impact of Food on Blood Sugar in People With Type 2 Diabetes
HealthPartners Institute 46 participants Est. completion 2013-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01237522
A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers
Not yet reported University of Southern Denmark 50 participants Est. completion 2010-12 1 siteOther conditions: Metformin, Organic Cation Transporter 2, Polymorphism,Single NucleotideView official trial listing → -
Completed NCT NCT01238978
Phase 4 Study in the Elderly Patients With T2DM
Not yet reported Novartis 46 participants Est. completion 2011-12 15 sitesType 2 diabetes Other conditions: ElderlyView official trial listing → -
Completed NCT NCT01240759
Safety and Efficacy of S-707106 in Subjects With Type 2 Diabetes Mellitus and Inadequate Glycemic Control With Metformin Therapy
Not yet reported Shionogi 218 participants Est. completion 2012-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01240785
Metformin Versus Insulin in Gestational Diabetes
Not yet reported Turku University Hospital 221 participants Est. completion 2012-12Other conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT01241448
A Study of LY2409021 in Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 263 participants Est. completion 2012-03 40 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01241669
Randomized, Placebo-controlled Study to Evaluate Effects of E5555 on Renal Function Parameters and OCT2 Activity
Not yet reported Eisai Inc. 104 participants 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT01243385
Metformin Hydrochloride as First-Line Therapy in Treating Patients With Locally Advanced or Metastatic Prostate Cancer
Not yet reported Swiss Cancer Institute 44 participants Est. completion 2019-08-09 9 sitesOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT01244646
Hypoglycemia- and Weight-related Quality of Life in Patients With Diabetes Mellitus Type 2 on Sulfonylurea Derivatives.
AstraZeneca 48 participants Est. completion 2012-08 22 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01245166
A Phase III Randomized, Double-blind, Parallel-group Study to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg Plus Acarbose 50 mg Tablets) Versus Acarbose Alone in Subjects With Type 2 Diabetes Mellitus
Not yet reported Lotus Pharmaceutical 220 participants Est. completion 2011-12 1 site Stand-aloneType 2 diabetes Other conditions: The Objectives of the Study is to Evaluate the Efficacy and Safety of Acarmet (Metformin HCl 500 mg, Plus Acarbose 50 mg Tablets) Thrice Daily Versus Acarbose 50 mg Thrice Daily Over 16 Weeks inView official trial listing → -
Completed NCT NCT01249677
Chronic Reduction of Fasting Glycaemia With Insulin Glargine Improves First and Second Phase Insulin Secretion in Patients With Type 2 Diabetes
Not yet reported Ruhr University of Bochum 14 participants Est. completion 2010-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01257334
Patients With Type 2 Diabetes Mellitus With Insufficient Glycaemic Control Despite Treatment With Metformin Alone or Metformin in Combination With a Sulfonylurea
Not yet reported Taipei Medical University WanFang Hospital 1390 participants Est. completion 2012-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01258075
Colesevelam for Children With Type 2 Diabetes
Not yet reported Daiichi Sankyo 236 participants Est. completion 2020-04-21 24 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01266486
Effect of Metformin on Breast Cancer Metabolism
Not yet reported Oxford University Hospitals NHS Trust 41 participants Est. completion 2014-05 3 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01267448
Outpatient Discharge Therapy With Saxagliptin+MetforminXR vs GlipizideXL for Type 2 Diabetes With Severe Hyperglycemia
Not yet reported Cook County Health 100 participants Est. completion 2015-07-25 1 siteType 2 diabetes Other conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT01269996
JanUmet Before Insulin Lantus In Eastern Population Evaluation Program (JUBILEE) In Type 2 Diabetic Patients
Not yet reported Chinese University of Hong Kong 71 participants Est. completion 2015-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01273571
A Pharmacokinetic and Pharmacodynamic Study of Metformin and Canagliflozin in Healthy Adult Volunteers
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 18 participants Est. completion 2011-02 Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01273584
Metformin in Obese Non-diabetic Pregnant Women
Not yet reported, Not yet reported Epsom and St Helier University Hospitals NHS Trust 450 participants Est. completion 2015-09 3 sitesOther conditions: Pregnancy Complications, ObesityView official trial listing → -
Completed NCT NCT01274130
Investigatory Study of Metformin's Pharmacokinetics, Pharmacodynamics and Drug Drug Interactions Classifying the Group by MATE1 Genotype in Healthy Volunteers
Not yet reported Yonsei University 30 participants Est. completion 2011-09 1 site Stand-aloneOther conditions: Healthy AdultView official trial listing → -
Completed NCT NCT01278160
Comparison of Biphasic Insulin Aspart 30 Twice Daily With Two Different Initial Dosage Split Regimens in Subjects With Type 2 Diabetes: An Extension to Trial BIASP-3756
Not yet reported Novo Nordisk A/S 179 participants Est. completion 2011-09 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01278485
Evaluation of Low Blood Sugar Events in Participants With Diabetes (MK-0431-402)
Merck Sharp & Dohme LLC 726 participants Est. completion 2012-06Type 2 diabetesView official trial listing → -
Completed NCT NCT01279512
Metformin Versus Acarbose Treatment in Infertile Overweight Women With Polycystic Ovary Syndrome (PCOS)
Not yet reported Royan Institute 50 participants Est. completion 2008-12 1 site Stand-aloneOther conditions: PCOView official trial listing → -
Completed NCT NCT01280409
Metformin Postpartum for GDM RCT for Reduced Weight Retention
Not yet reported The University of Texas Health Science Center, Houston 114 participants Est. completion 2014-08 2 sites Stand-aloneOther conditions: Diabetes, GestationalView official trial listing → -
Completed NCT NCT01283308
A Randomized Trial of Diabetes Prevention Through Lifestyle Change in India
Not yet reported Emory University 599 participants Est. completion 2013-11 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT01286233
Study of Biomarkers Associated With Fatigue in Patients With Early-Stage Breast Cancer Treated With Metformin or Placebo on NCIC-CTG-MA.32
NSABP Foundation Inc 394 participants Est. completion 2016-09 256 sitesOther conditions: Breast Cancer, Depression, Fatigue, Sleep DisordersView official trial listing → -
Completed NCT NCT01289119
Efficacy and Safety of Alogliptin in Participants With Type 2 Diabetes
Not yet reported Takeda 506 participants Est. completion 2011-12 21 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01289990
Safety and Efficacy of Empagliflozin (BI 10773) and Sitagliptin Versus Placebo Over 76 Weeks in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 2705 participants Est. completion 2013-05 243 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01290575
Multiple Ascending Dose Study of BMS-820132 in Patients With Type 2 Diabetes
Not yet reported Bristol-Myers Squibb 67 participants Est. completion 2011-11 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01292993
A Study to Evaluate the Interaction of LX4211 and Metformin in Healthy Subjects
Not yet reported Lexicon Pharmaceuticals 18 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01294553
An Open Label, Multi-centre, Non-interventional Post-marketing Surveillance to Monitor the Safety and/or Efficacy of AVANDAMET Between June 2004 and January 2010
GlaxoSmithKline 717 participants Est. completion 2010-01Type 2 diabetesView official trial listing → -
Completed NCT NCT01296412
Comparison of Two Treatment Regimens (Sitagliptin Versus Liraglutide) on Participants Who Failed to Achieve Good Glucose Control on Metformin Alone (MK-0431-403)
Not yet reported Merck Sharp & Dohme LLC 653 participants Est. completion 2012-02-29 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01298518
A Multiple Dose Study Of PF-04620110 In Type 2 Diabetes Patients
Not yet reported Pfizer 48 participants Est. completion 2011-05 3 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01300637
Effects of Adjunctive Metformin on Metabolic Profiles in Clozapine-treated Schizophrenic Patients
Not yet reported Taipei Medical University WanFang Hospital 60 participants Est. completion 2011-07 1 siteMetabolic syndrome Other conditions: Obesity, SchizophreniaView official trial listing → -
Withdrawn NCT NCT01302002
The Use of Metformin in Early Breast Cancer Patients Pre-Surgery
Not yet reported Instituto Nacional de Cancer, Brazil Est. completion 2016-02 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01302145
Drug to Drug Interaction Study With ASP1941 and Metformin
Not yet reported Astellas Pharma Inc 36 participants Est. completion 2009-12-09 5 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01302379
Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors
Not yet reported University of California, San Diego 333 participants Est. completion 2016-12 1 siteOther conditions: Breast NeoplasmsView official trial listing → -
Status unknown NCT NCT01303055
Effects of Alogliptin on Pancreatic Beta Cell Function
Not yet reported Aichi Gakuin University 80 participants Est. completion 2014-12 4 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01305551
BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States
Not yet reported AstraZeneca Est. completion 2011-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01306214
Safety and Efficacy of BI 10773 as add-on to Insulin Regimen in Patients With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 566 participants Est. completion 2013-04 103 sitesType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT01307306
Glucose Control in Severely Burned Patients
Not yet reported Sunnybrook Health Sciences Centre 45 participants Est. completion 2018-03 1 site Stand-aloneOther conditions: BurnsView official trial listing → -
Completed NCT NCT01310231
A Trial of Standard Chemotherapy With Metformin (vs Placebo) in Women With Metastatic Breast Cancer
Not yet reported Ozmosis Research Inc. 40 participants Est. completion 2018-03-26 5 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT01310452
Study on Liver Fat Content and Visceral Fat Mass in Overweight and Obese Type 2 Diabetes Patients After Treatment With Basal Insulin
Not yet reported Fudan University 50 participants 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01312467
Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI
Not yet reported National Cancer Institute (NCI) 45 participants Est. completion 2014-12 4 sites Stand-aloneOther conditions: Adenomatous Polyp, Colorectal Cancer, ObesityView official trial listing → -
Terminated NCT NCT01316042
Metformin for the Treatment of Premature Pubarche in Girls
Not yet reported Milton S. Hershey Medical Center 4 participants Est. completion 2014-04 3 sitesOther conditions: Premature PubarcheView official trial listing → -
Completed NCT NCT01318109
Efficacy and Safety of Alogliptin Used Combination With Metformin in Participants With Type 2 Diabetes in Japan
Not yet reported, Not yet reported Takeda 288 participants Est. completion 2009-04Type 2 diabetesView official trial listing → -
Completed NCT NCT01318135
Long-term Safety Study of Alogliptin Used in Combination With Sulfonylurea or Metformin in Participants With Type 2 Diabetes in Japan
Not yet reported, Not yet reported Takeda 576 participants Est. completion 2010-04Type 2 diabetesView official trial listing → -
Completed NCT NCT01318564
Diabetic Treatment Adherence
M.D. Anderson Cancer Center 28 participants Est. completion 2016-08 2 sitesOther conditions: Endocrine System DiseasesView official trial listing → -
Completed NCT NCT01319994
Prevention of Metabolic Complications of Glucocorticoid Excess
Not yet reported, Not yet reported Barts & The London NHS Trust 57 participants Est. completion 2015-01 1 site Stand-aloneOther conditions: Iatrogenic Cushing DiseaseView official trial listing → -
Completed NCT NCT01324180
Vincristine, Dexamethasone, Doxorubicin, and PEG-asparaginase (VPLD) and Metformin for Relapsed Childhood Acute Lymphoblastic Leukemia (ALL)
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 14 participants Est. completion 2017-07-27 5 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01329016
Glyburide and Metformin for Gestational Diabetes Mellitus (GDM)
Not yet reported, Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 177 participants Est. completion 2015-02-28 4 sitesOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT01332071
Avandamet Bioequivalence Study Brazil - Fed Administration
Not yet reported GlaxoSmithKline 26 participants Est. completion 2009-12-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01332370
Prescription Patterns, Resource Utilization & Costs - Add-on Therapy With Anti Dipeptidyl Peptidase-IVs vs Rosiglitazone
GlaxoSmithKline 5391 participants Est. completion 2010-12Type 2 diabetesView official trial listing → -
Terminated NCT NCT01333852
Metformin Plus Paclitaxel for Metastatic or Recurrent Head and Neck Cancer
Not yet reported Lucas Vieira dos Santos 45 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Head and Neck Neoplasms, Squamous Cell CarcinomaView official trial listing → -
Completed NCT NCT01334125
Adjunctive Metformin Therapy in Double Diabetes
Not yet reported University of Massachusetts, Worcester 28 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01336322
Metformin and Sitagliptin in Women With Previous Gestational Diabetes
Not yet reported University of Pisa 40 participants Est. completion 2018-12 1 sitePrediabetesView official trial listing → -
Terminated NCT NCT01336673
Glucophage XR® Observational Study
Merck KGaA, Darmstadt, Germany 518 participants Est. completion 2013-06 1 siteType 2 diabetes Other conditions: GI Side EffectView official trial listing → -
Completed NCT NCT01336751
Lantus Versus Humalog Mix as add-on Therapy in Type Diabetes Patients Failing Sulfonylurea and Metformin Combination Treatment
Not yet reported Sanofi 212 participants Est. completion 2002-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01338870
Study of Safety and Efficacy of PF-04991532 in Subjects With Type 2 Diabetes
Not yet reported Pfizer 301 participants Est. completion 2012-03 42 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01339143
Compare the Effect of DPP-IV Inhibitor or TZD on Glycemic Variability and Oxidative Stress in Patient With 2 Diabetes
Not yet reported Korea University Anam Hospital 80 participants Est. completion 2013-05 1 siteOther conditions: Diabetes Mellitus, Oxidative StressView official trial listing → -
Completed NCT NCT01340300
Exercise and Metformin in Colorectal and Breast Cancer Survivors
Not yet reported Dana-Farber Cancer Institute 139 participants Est. completion 2017-12 2 sitesOther conditions: Colorectal Cancer, Breast CancerView official trial listing → -
Completed NCT NCT01340664
An Efficacy, Safety, and Tolerability Study of Canagliflozin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy
Not yet reported Janssen Research & Development, LLC 279 participants Est. completion 2012-04 61 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01341717
Effects of Sitagliptin on Type 2 Diabetes Mellitus Patients on Treatment With Metformin and Insulin
Not yet reported Jothydev's Diabetes and Research Centre 440 participants Est. completion 2014-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01341795
Genetic Variation in the Transporters and Hypoglycemic Agents
Ajou University School of Medicine 100 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01341886
Effect of Metformin on Decrement in Levothyroxin Dose Required for Thyroid Stimulating Hormone (TSH) Suppression in Patients With Differentiated Thyroid Cancer
Not yet reported Mashhad University of Medical Sciences 51 participants Est. completion 2011-04 1 siteOther conditions: Malignant Neoplasm of Thyroid Stage I, Malignant Neoplasm of Thyroid Stage IIView official trial listing → -
Status unknown NCT NCT01342042
The Safety,Preliminary Pharmacodynamics and Pharmacokinetics Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 36 participants Est. completion 2011-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01342614
The Effect of Metformin on the Correlation Between Hyperinsulinemia and Hypertension
Not yet reported China-Japan Friendship Hospital 140 participants Est. completion 2009-08 Stand-aloneOther conditions: Diabetes Mellitus, Essential HypertensionView official trial listing → -
Status unknown NCT NCT01342744
Metformin in Postmenopausal Women With Metabolic Syndrome
Not yet reported Mahidol University 40 participants Est. completion 2012-03 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT01349387
Effect of Treatment With Metformin in Type 2 Diabetes Patients on Alternative Genes Splicing
Not yet reported Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète 25 participants Est. completion 2012-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01351753
Drug Therapy Induced Weight Loss to Improve Blood Vessel Function in Subjects With Obesity
Not yet reported University of Iowa 128 participants Est. completion 2014-01-09 1 site Stand-aloneMetabolic syndrome Other conditions: ObesityView official trial listing → -
Withdrawn NCT NCT01352026
Evaluation of Metformin Activity in Addition to Conventional Treatment of Grade II or III Pulmonary Arterial Hypertension (PAH)
Not yet reported Nantes University Hospital 2 sites Stand-aloneOther conditions: Pulmonary Arterial HypertensionView official trial listing → -
Completed NCT NCT01353391
Metformin in Women With Type 2 Diabetes in Pregnancy Trial
Not yet reported Mount Sinai Hospital, Canada 500 participants Est. completion 2019-06-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01356381
Study to Assess the Effect of 24 Weeks of Treatment With Vildagliptin in Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 43 participants Est. completion 2013-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01357135
An Observational Study of Type II Diabetics Treated With Dual Therapy With or Without Sitagliptin (Januvia®/Xelevia®, MK-0431-201)
Merck Sharp & Dohme LLC 3453 participants Est. completion 2013-08-31Type 2 diabetesView official trial listing → -
Terminated NCT NCT01357148
A Post Marketing Safety Study of Sitagliptin Phosphate/Metformin Hydrochloride (JANUMET®) (MK-0431A-235)
Merck Sharp & Dohme LLC 143 participants Est. completion 2010-05Type 2 diabetesView official trial listing → -
Completed NCT NCT01357876
Effect of Metformin on Gut Peptides , Bile Acids and Lipid Profiles in Type 2 Diabetics
Not yet reported GlaxoSmithKline 8 participants Est. completion 2011-07-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01358994
Metformin Treatment, Renal Function and Lactic Acidosis
Skane University Hospital 4500 participants Est. completion 2011-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01364350
TODAY2 Phase 1 Immediate Post-Intervention Observational Follow-up Study
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 550 participants Est. completion 2014-02 16 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01364675
Primary Prevention of Cardiovascular Disease (CVD) in Pre-diabetic & Pre-hypertensive Subjects
Not yet reported Ramathibodi Hospital 8900 participants Est. completion 2016-12 1 sitePrediabetes Other conditions: Pre-hypertensionView official trial listing → -
Completed NCT NCT01365091
Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-Brazil
Not yet reported AstraZeneca 112 participants Est. completion 2011-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01366391
Therapeutic Monitoring of Metformin in Women With Polycystic Ovary Syndrome
Not yet reported Biocinese 24 participants Est. completion 2011-10 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT01367054
Adverse Events in Pharmaceutical Bioequivalence Study of Two Formulations of Metformine Hydrochloride 500 mg
Not yet reported Biocinese 26 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Nutritional and Metabolic DiseasesView official trial listing → -
Completed NCT NCT01368081
Empagliflozin (BI 10773) Comprehensive add-on Study in Japanese Subjects With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 1162 participants Est. completion 2013-04 87 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01370707
A Study to Evaluate the Efficacy and Safety of CJ-30001 and CJ-30002 in Type 2 Diabetes Mellitus Patients
Not yet reported HK inno.N Corporation 187 participants Est. completion 2012-07 21 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01376557
Safety and Efficacy of LX4211 With Metformin in Type 2 Diabetes Patients With Inadequate Glycemic Control on Metformin
Not yet reported Lexicon Pharmaceuticals 299 participants Est. completion 2012-05 56 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01381900
A Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Alone or in Combination With a Sulphonylurea
Not yet reported Janssen Research & Development, LLC 678 participants Est. completion 2012-11 25 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01383356
Comparison of the Bioavailability of Metformin Between Medium Dose Linagliptin/Metformin Tablets and Medium Dose Glucophage Tablet Given With Linagliptin Tablet
Not yet reported Boehringer Ingelheim 58 participants Est. completion 2011-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01388361
Comparison of the Efficacy and Safety of Two Intensification Strategies in Subjects With Type 2 Diabetes Inadequately Controlled on Basal Insulin and Metformin
Not yet reported Novo Nordisk A/S 413 participants Est. completion 2012-07 124 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT01389778
Polycystic Ovary Syndrome Genetics and Treatment Response
Not yet reported Massachusetts General Hospital 200 participants Est. completion 2019-10 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01392677
Evaluation of Safety and Efficacy of Dapagliflozin in Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control on Background Combination of Metformin and Sulfonylurea
Not yet reported AstraZeneca 311 participants Est. completion 2013-08 42 sitesType 2 diabetes Other conditions: High HbA1c Level, Inadequate Glycaemic ControlView official trial listing → -
Completed NCT NCT01394887
Metformin & Inflammation in Pre-diabetic Children
Not yet reported, Not yet reported Coordinación de Investigación en Salud, Mexico 52 participants Est. completion 2011-07 1 siteOther conditions: Glucose Intolerance, Inflammation, DiabetesView official trial listing → -
Completed NCT NCT01396564
Pioglitazone and Metformin in Diabetic Children
Not yet reported, Not yet reported Coordinación de Investigación en Salud, Mexico 56 participants Est. completion 2011-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01399645
Study of Liraglutide Versus Insulin on Liver Fat Fraction in Patients With Type 2 Diabetes
Not yet reported Centre hospitalier de l'Université de Montréal (CHUM) 35 participants Est. completion 2014-06 1 site Stand-aloneMASLDMASHType 2 diabetesView official trial listing → -
Completed NCT NCT01400191
The Inhibitory Effect of Metformin on Gluconeogenesis in Relation to Polymorphisms in Organic Cation Transporter 1
Not yet reported University of Southern Denmark 37 participants Est. completion 2012-12 1 siteOther conditions: Pharmacogenetics of MetforminView official trial listing → -
Completed NCT NCT01404676
The Effect of Vildagliptin Based Treatment Versus Sulfonylurea on Glycemic Variability, Oxidative Stress, GLP-1, and Endothelial Function in Patients With Type 2 Diabetes
Not yet reported Samsung Medical Center 34 participants Est. completion 2012-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01404715
Drug-drug Interaction Study With Metformin and Imatinib
Not yet reported University of California, San Francisco 11 participants Est. completion 2013-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01405118
Effect Of CP-690,550 On The Pharmacokinetics Of Metformin In Healthy Volunteers
Not yet reported Pfizer 24 participants Est. completion 2011-07 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT01408095
A Study in Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 240 participants Est. completion 2012-09 38 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01409395
Drug-Drug Interaction Study With Metformin and Nizatidine
Not yet reported University of California, San Francisco 10 participants Est. completion 2013-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01410604
Adipokines in Obese Adolescents With Insulin Resistance
Not yet reported Hospital Regional de Alta Especialidad del Bajio 31 participants Est. completion 2010-03 2 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT01417897
Human Insulin Analogs: Evaluation of Inflammatory mRNA Expression of Macrophages and Endothelial Function of Short-acting Insulin - HERMES Pilot Study
Not yet reported ikfe-CRO GmbH 12 participants Est. completion 2012-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01420692
The Effects of Insulin Detemir and Gliclazide-MR Treatments on Endothelial Functions in Patients With Type 2 Diabetes
Not yet reported Ankara University 64 participants Est. completion 2012-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01421459
A Study in Adults With Type 2 Diabetes
Not yet reported Eli Lilly and Company 759 participants Est. completion 2012-09 62 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01422746
Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess
Not yet reported University of Virginia 20 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Obesity, Hyperandrogenemia, Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01422876
Efficacy and Safety of Empagliflozin (BI 10773) / Linagliptin (BI 1356) Fixed Dose Combination in Treatment naïve and Metformin Treated Type 2 Diabetes Patients
Not yet reported Boehringer Ingelheim 1405 participants Est. completion 2013-09 211 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01423487
Efficacy and Safety of Metformin in Preventing Patients With Risperidone From Weight Gain and Amenorrhea
Not yet reported Central South University Est. completion 2013-08 1 site Stand-aloneOther conditions: Weight Gain, AmenorrheaView official trial listing → -
Completed NCT NCT01425580
Liraglutide and Heart Failure in Type 2 Diabetes
Not yet reported Thomas Nystrom 62 participants Est. completion 2016-08 2 sites Added to GLP-1Heart failureType 2 diabetesView official trial listing → -
Completed NCT NCT01426399
Pharmacokinetic/Pharmacodynamic Drug-drug Interaction of LC15-0444 and Metformin After Oral Administration in Healthy Male Subjects
Not yet reported LG Life Sciences 30 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01426737
The Swiss Glucose Variability Study
Not yet reported University of Zurich 50 participants Est. completion 2013-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01426802
Vildagliptin 50 mg Twice Daily in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin
Not yet reported Novartis Pharmaceuticals 150 participants Est. completion 2011-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01427595
Effect of Metformin on Sensitivity of the GnRH Pulse Generator to Suppression by Estradiol and Progesterone
Not yet reported University of Virginia 25 participants Est. completion 2015-01-17 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, HyperandrogenismView official trial listing → -
Completed NCT NCT01427920
Comparison of Biphasic Insulin Aspart 30 Individually Adjusted by the Subject and the Trial Physician, Both Combined With Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 348 participants Est. completion 2012-07 41 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01429506
Efficacy of Laparoscopic Sleeve Gastrectomy and Intensive Medical Management in Obese Type 2 Diabetes
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2012-08 1 siteOther conditions: Diabetes Mellitus, ObesityView official trial listing → -
Completed NCT NCT01429818
Endothelial Disfunction Treatment With Glimepiride/Metformin Combination (Glimetal) in Type 2 Diabetes Patients
Not yet reported Laboratorios Silanes S.A. de C.V. 16 participants Est. completion 2008-01 1 site Stand-aloneOther conditions: Endothelial Dysfunction, Diabetes MellitusView official trial listing → -
Terminated NCT NCT01430351
Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy
Not yet reported M.D. Anderson Cancer Center 144 participants Est. completion 2025-02-02 1 site Stand-aloneObstructive sleep apnea Other conditions: Glioblastoma, Supratentorial GlioblastomaView official trial listing → -
Completed NCT NCT01433913
Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery
Not yet reported National Cancer Institute (NCI) 20 participants Est. completion 2014-04 3 sites Stand-aloneOther conditions: Adenocarcinoma of the Prostate, Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate CancerView official trial listing → -
Completed NCT NCT01434186
A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination With Metformin IR or Metformin XR in Pediatric Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone
Not yet reported AstraZeneca 32 participants Est. completion 2016-04 16 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01437800
BIOAVAILABILITY OF GLI/METXR (4/850 mg)
Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2011-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01437813
BIOAVAILABILITY OF Glimepiride/Extended Release Metformin (GLI/METXR): High Fat Diet Study
Not yet reported Laboratorios Silanes S.A. de C.V. 24 participants Est. completion 2011-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01438190
Metformin in Step-down Regimen Versus Conventional Low Dose Step-up Protocol in Patients With PCOS Undergoing IVF
Not yet reported University of Modena and Reggio Emilia 120 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Infertility, PCOSView official trial listing → -
Completed NCT NCT01438723
The Metformin in Coronary Artery Bypass Graft (CABG) (MetCAB) Trial
Not yet reported Radboud University Medical Center 100 participants Est. completion 2014-07 1 site Stand-aloneCardiovascular disease Other conditions: Ischemic Heart DiseaseView official trial listing → -
Completed NCT NCT01438814
Linagliptin in Combination With Metformin in Treatment Naive Patients With Type 2 Diabetes Mellitus and Insufficient Glycaemic Control
Not yet reported Boehringer Ingelheim 689 participants Est. completion 2013-03 90 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01440127
Impact of Pretreatment With Metformin on Colorectal Cancer Stem Cells (CCSC) and Related Pharmacodynamic Markers
Not yet reported Tufts Medical Center 9 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: Colon CancerView official trial listing → -
Completed NCT NCT01441869
Study in Healthy Subjects to Measure Amount of Drug in Blood After Dosing With Different Saxagliptin / Metformin Produc
Not yet reported AstraZeneca 28 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Bioequivalence, Log-transformed AUCss and Cmax,ss Values for Saxagliptin and MetforminView official trial listing → -
Completed NCT NCT01442870
Evaluation of Clinical Safety of Combining Metformin With Anticancer Chemotherapy
Not yet reported Tufts Medical Center 105 participants Est. completion 2014-11 1 site Stand-aloneOther conditions: CancerView official trial listing → -
Completed NCT NCT01443221
Pharmacokinetics of Mitiglinide and Metformin in Free Combination and Fixed-dose Combination in Healthy Male Subjects.
Not yet reported JW Pharmaceutical 24 participants Est. completion 2011-01 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01444248
Compare the Compliance of Patients Treated With Once-daily (od) or Twice-daily (Bid) Glimepiride and Metformin Fixed Combination Therapy
Not yet reported Handok Inc. 168 participants Est. completion 2012-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01452451
Safety, Tolerability, Pharmacokinetics,Pharmacodynamics Study of LAPS-Exendin in Subjects of Type 2 Diabetes Mellitus
Not yet reported Hanmi Pharmaceutical Company Limited 72 participants 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01454622
A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (50 mg/1,000 mg) With Respect to the Individual Components of Canagliflozin (1 x 100 mg) and Metformin IR Tablets (2 x 1,000 mg) in Healthy Volunteers
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 64 participants Est. completion 2011-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01455870
A Study to Evaluate ITCA 650 Compared to Sitagliptin as add-on Therapy for the Treatment of Type 2 Diabetes
Not yet reported Intarcia Therapeutics 535 participants Est. completion 2015-07 54 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01455883
A Study to Evaluate ITCA 650 Compared to Glimepiride for the Treatment of Type 2 Diabetes
Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01455909
A Study to Evaluate ITCA 650 Compared to Sitagliptin for the Treatment of Type 2 Diabetes
Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01455922
A Study to Evaluate ITCA 650 Compared to Glimepiride as Add on Therapy for the Treatment of Type 2 Diabetes
Not yet reported Intarcia Therapeutics Est. completion 2014-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01457911
Evaluation of Fixed Dose Combination of Glimepiride and Metformin in Chinese Type 2 Diabetes Patients Inadequately Controlled With Metformin
Not yet reported Sanofi 244 participants Est. completion 2013-02 22 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01459094
Effect of Food on a Fixed Dose Combination Tablet of Canagliflozin and Metformin Immediate Release in Healthy Volunteers
Not yet reported Janssen Research & Development, LLC 24 participants Est. completion 2011-12Other conditions: HealthyView official trial listing → -
Status unknown NCT NCT01459445
Metformin+ Drospirenone/ethinylestradiol30µg and Flow-mediated Dilation in Polycystic Ovary Syndrome
Not yet reported Iuliu Hatieganu University of Medicine and Pharmacy 26 participants Est. completion 2012-01 1 siteOther conditions: Polycystic Ovary Syndrome, Endothelial DysfunctionView official trial listing → -
Completed NCT NCT01459809
Efficacy and Safety Comparison of Metformin/Glimepiride Combination Versus Each Compound Alone in New Diagnosed Type 2 Diabetes Patients
Not yet reported Sanofi 538 participants Est. completion 2014-01 55 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01460797
Metabolic Effects of a Caloric Restriction High/Low Glycemic Index Diet Plus Metformin in Overweight/Obese Subjects
Not yet reported Caio Eduardo Gonçalves Reis 41 participants Est. completion 2006-10 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT01462266
Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260)
Not yet reported Merck Sharp & Dohme LLC 660 participants Est. completion 2013-06-07 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01463228
A Study to Assess the Bioequivalence of Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers
Not yet reported Janssen Research & Development, LLC 83 participants Est. completion 2012-01 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01463774
A Study to Assess the Bioequivalence of 2 Fixed Dose Combination Tablets of Canagliflozin and Metformin Immediate Release (IR) With Respect to the Individual Components of Canagliflozin and Metformin IR Tablets in Healthy Volunteers
Not yet reported Janssen Research & Development, LLC 74 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01464437
AMG 151 Amgen Protocol Number 20100761
Not yet reported Amgen 236 participants Est. completion 2012-12 77 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01465113
Vitamin D Supplementation on 15-Prostaglandin Dehydrogenase Expression in Barrett's Esophagus
Not yet reported Case Comprehensive Cancer Center 26 participants Est. completion 2016-02 3 sites Stand-aloneOther conditions: Short Segment Barrett's Esophagus, Long Segment Barrett's EsophagusView official trial listing → -
Completed NCT NCT01465152
Comparison of Metformin, Repaglinide or the Combination of Both in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 182 participants Est. completion 2004-10-21 18 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT01471275
Chinese Medicine Treatment of Obesity With Type 2 Diabetes, Dyslipidemia
Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 450 participants Est. completion 2013-12 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01471808
Effects of Different Early Intensive Therapies on Long-term β-cell Function
Not yet reported Sun Yat-sen University 264 participants Est. completion 2018-12Type 2 diabetesView official trial listing → -
Completed NCT NCT01472432
DPP IV Inhibition Facilitates Healing of Chronic Foot Ulcers in Type 2 Diabetes
Not yet reported University of Campania Luigi Vanvitelli 106 participants Est. completion 2016-01 1 site Stand-aloneOther conditions: Chronic Foot UlcersView official trial listing → -
Completed NCT NCT01474018
QR-Bromocriptine as an Adjunct to Insulin and Metformin in the Treatment of Type 2 Diabetes
Not yet reported University of Texas Southwestern Medical Center 15 participants Est. completion 2012-06 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01474967
Effect of Dosage of Metformin on Menstruation and Lipid Profile in Women With Polycystic Ovary Syndrome
Not yet reported Hormozgan University of Medical Sciences 50 participants Est. completion 2011-02 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01475461
Phase 2 Study To Evaluate Safety And Efficacy Of Investigational Drug - PF04937319 In Patients With Type 2 Diabetes
Not yet reported Pfizer 345 participants Est. completion 2013-01 63 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01476475
Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Combination Versus Insulin Glargine Alone on Top of Metformin in Type 2 Diabetic Patients
Not yet reported Sanofi 323 participants Est. completion 2012-12 70 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Terminated NCT NCT01477060
Modulation of Response to Hormonal Therapy With Lapatinib and/or Metformin in Patients With Metastatic Breast Cancer
Not yet reported Fondazione Michelangelo 32 participants Est. completion 2013-12 11 sitesOther conditions: Metastatic Breast CancerView official trial listing → -
Terminated NCT NCT01477853
A Study of the Co-administration of Sitagliptin and Atorvastatin in Inadequately Controlled Type 2 Diabetes Mellitus (MK-0431E-211)
Not yet reported Merck Sharp & Dohme LLC 166 participants Est. completion 2012-12-04 Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01478308
Metformin With Standard Taxotere and Prednisone in the Treatment of Castration Resistant Prostate Cancer
Not yet reported New Mexico Cancer Research Alliance Est. completion 2011-10Other conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT01481116
Efficacy and Safety of TAK-875 Compared to Glimepiride When Used With Metformin in Participants With Type 2 Diabetes
Not yet reported Takeda 2454 participants Est. completion 2014-04 226 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01482286
Effect of Weight and Insulin Sensitivity on Reproductive Function in PCOS
Not yet reported Pennington Biomedical Research Center 32 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01483560
REducing With MetfOrmin Vascular Adverse Lesions in Type 1 Diabetes (REMOVAL)
Not yet reported University of Glasgow 493 participants Est. completion 2017-04-18 24 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01483781
A Study of the Effects of Canagliflozin on Plasma Volume in Patients With Type 2 Diabetes Mellitus
Not yet reported Janssen Research & Development, LLC 36 participants Est. completion 2012-08 1 siteType 2 diabetes Other conditions: Plasma VolumeView official trial listing → -
Completed NCT NCT01485614
Study to Assess Safety & Efficacy of Sitagliptin as Initial Oral Therapy for Treatment of Type 2 Diabetes Mellitus in Pediatric Participants. (MK-0431-083)
Not yet reported Merck Sharp & Dohme LLC 200 participants Est. completion 2019-10-09 Stand-aloneType 2 diabetes Other conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT01486966
Comparing Efficacy and Safety of Insulin Detemir Plus Insulin Aspart and NPH Insulin Plus Human Soluble Insulin With or Without Metformin in Chinese Patients With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 58 participants Est. completion 2012-06 6 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01487993
Metformin in Obese Children and Adolescents
Not yet reported St. Antonius Hospital 62 participants Est. completion 2017-02-28 2 sitesOther conditions: Obesity, Insulin ResistanceView official trial listing → -
Completed NCT NCT01488552
Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancer
Not yet reported, Not yet reported Pancreatic Cancer Research Team 60 participants Est. completion 2016-08 5 sites Stand-aloneOther conditions: Stage IV Pancreatic CancerView official trial listing → -
Completed NCT NCT01489644
Single Dose Pharmacokinetics of Repaglinide, Metformin and Combination Tablet in Healthy Volunteers
Not yet reported Novo Nordisk A/S 62 participants Est. completion 2006-07 2 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01490658
Single Dose Pharmacokinetics of Repaglinide, Metformin and Combination Tablet in Fed Healthy Volunteers
Not yet reported Novo Nordisk A/S 93 participants Est. completion 2006-08 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01490918
Study to Evaluate the Efficacy of Acarbose,Metformin,Sitagliptin Combination Treatment in DM Patients
Not yet reported The Catholic University of Korea 165 participants Est. completion 2014-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01496430
Efficacy and Safety of Azilsartan Medoxomil Used in Combination With Metformin in Participants With Hypertension and Diabetes
Not yet reported Takeda 105 participants Est. completion 2013-05 68 sitesOther conditions: Hypertension, DiabetesView official trial listing → -
Completed NCT NCT01497522
Efficacy and Safety of Vildagliptin as add-on Therapy to Metformin in Patients With Type 2 Diabetes
Not yet reported Novartis Pharmaceuticals 183 participants Est. completion 2013-02 20 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01505426
A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Metformin in Asian Diabetes Patients
Not yet reported Astellas Pharma Inc 171 participants Est. completion 2013-01-14 12 sites Stand-aloneOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT01508182
A Study of Canagliflozin and Metformin Immediate Release (150 mg/500 mg) FDC Tablets in Healthy Volunteers
Not yet reported Janssen Research & Development, LLC 64 participants Est. completion 2012-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01508195
A Study of Canagliflozin and Metformin Immediate Release (50 mg/500 mg) FDC Tablets in Healthy Volunteers
Not yet reported Janssen Research & Development, LLC 64 participants Est. completion 2012-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01509001
Study of Metabolic and Haemodynamic Effects of Metformin and Glimepiride in Patients With Type 2 Diabetes Mellitus
Not yet reported University of Sao Paulo 20 participants Est. completion 2012-01 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01510522
Evaluate Adherence to Treatment With Glucophage Sachets Versus Tablets in Diabetes Type 2 Patients Previously Treated With Metformin Tablets
Not yet reported Merck KGaA, Darmstadt, Germany Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01511172
Effect of Liraglutide as add-on to Metformin Compared to Either Liraglutide or Metformin Alone, or to a Combination of Metformin and a SU (Sulphonylurea) Agent in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 145 participants Est. completion 2002-12 41 sites MixedType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01511198
Efficacy and Safety of Metformin and Liraglutide in Obese Subjects With Type 2 Diabetes Previously Treated With an Oral Hypoglycemic Agent
Not yet reported Novo Nordisk A/S 223 participants Est. completion 2001-10 39 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01512979
Linagliptin and Metformin Versus Linagliptin in Newly Diagnosed, Untreated Type 2 Diabetes
Not yet reported Boehringer Ingelheim 316 participants Est. completion 2013-04 82 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01513590
A Trial Comparing Efficacy and Safety of Insulin Degludec/Insulin Aspart and BIAsp 30 in Insulin naïve Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 394 participants Est. completion 2012-11-19 49 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT01514149
Dose-Ranging Study to Evaluate Efficacy and Safety of Weekly CJC-1134-PC in Patients With T2DM on Metformin Monotherapy
Not yet reported ConjuChem 73 participants Est. completion 2013-03 22 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01517373
Study To Understand Efficacy And Safety Of Investigational Agent (PF-04937319) Compared To Approved Agent (Glimepiride) In Patients With Diabetes On Metformin
Not yet reported Pfizer 304 participants Est. completion 2013-01 53 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01517412
Comparison of Lixisenatide Injected Prior to the Main Meal of the Day Versus Prior to Breakfast in Type 2 Diabetic Patients on Metformin
Not yet reported Sanofi 451 participants Est. completion 2013-05 82 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01518101
Vildagliptin Versus Liraglutide - Patient Preference After Receiving Both Medications
Not yet reported Novartis Pharmaceuticals 62 participants Est. completion 2012-10 8 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01518712
A Study to Assess the Bioequivalence of 2 Fixed Dose Combination (FDC) Tablets of Canagliflozin and Metformin Immediate Release (IR) (150 mg/850 mg) With Respect to the Individual Components of Canagliflozin (1 x 300 mg) and Metformin IR Tablets (2 x 850 mg) in Healthy Volunteers
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 64 participants Est. completion 2011-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01519674
Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and Metformin
Not yet reported Novo Nordisk A/S 582 participants Est. completion 2013-10 69 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT01523639
A Randomized, Placebo-controlled, Double-blind Phase II Study Evaluating if Glucophage Can Avoid Liver Injury Due to Chemotherapy Associated Steatosis
Not yet reported Austrian Breast & Colorectal Cancer Study Group 8 participants Est. completion 2014-04 7 sitesOther conditions: Colorectal Cancer, SteatohepatitisView official trial listing → -
Completed NCT NCT01524705
FLuctuATion Reduction With inSULin and Glp-1 Added togetheR (FLAT-SUGAR)
Not yet reported University of Washington 102 participants Est. completion 2014-07 12 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Terminated NCT NCT01525225
Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DM
Not yet reported AstraZeneca 4 participants Est. completion 2013-06 7 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01525823
Assessment of Blood Glucose Changes in Healthy Volunteers After BMS-754807 Alone or BMS-754807 With Metformin
Not yet reported Bristol-Myers Squibb 26 participants Est. completion 2012-04 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT01526317
A Phase 1 Clinical Trial to Investigate Pharmacokinetics and Drug Interaction of Crestor and Glucodown OR SR in Healthy Volunteers
Not yet reported Yuhan Corporation 36 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: Pharmacokinetics and Drug Interaction of Crestor and Glucodown SRView official trial listing → -
Completed NCT NCT01526616
Spironolactone Plus Metformin in Polycystic Ovary Syndrome
Not yet reported University Magna Graecia 56 participants Est. completion 2011-07Other conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01528046
Metformin in Children With Relapsed or Refractory Solid Tumors
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 26 participants Est. completion 2020-02-03 14 sites Stand-aloneOther conditions: Solid Tumors, Primary Brain TumorsView official trial listing → -
Completed NCT NCT01528254
VERIFY:A Study to Compare Combination Regimen With Vildagliptin & Metformin Versus Metformin in Treatment-naïve Patients With Type 2 Diabetes Mellitus
Not yet reported Novartis Pharmaceuticals 2004 participants Est. completion 2019-04-04 227 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01529177
Metformin for the Treatment of Unexplained Oligozspermia
Not yet reported The Egyptian IVF-ET Center 600 participants Est. completion 2017-02 1 site Stand-aloneOther conditions: InfertilityView official trial listing → -
Completed NCT NCT01529541
Efficacy and Safety of CWP-0403 Compared to Sitagliptin in Patients With Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin Alone
Not yet reported JW Pharmaceutical 200 participants Est. completion 2013-10 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT01529593
Temsirolimus in Combination With Metformin in Patients With Advanced Cancers
Not yet reported M.D. Anderson Cancer Center 34 participants Est. completion 2025-03-14 1 site Stand-aloneOther conditions: Advanced CancersView official trial listing → -
Completed NCT NCT01535677
To Compare the Similarity of a Combination Dapagliflozin/Metformin Tablet With the Two Drugs Administered Separately
Not yet reported AstraZeneca 71 participants Est. completion 2013-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01540487
Pharmacokinetics of Fixed Dose Combination (FDC) Tablets of Linagliptin /Metformin
Not yet reported Boehringer Ingelheim 48 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01541215
Efficacy and Safety of Liraglutide in Combination With Metformin Compared to Metformin Alone, in Children and Adolescents With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 135 participants Est. completion 2020-05-20 185 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01541956
Efficacy of VIldagliptin aS an Add-on Therapy to Metformin Compared to Metformin Up-TitratION in Chinese Patients With Type 2 Diabetes.(VISION)
Not yet reported Novartis Pharmaceuticals 3091 participants Est. completion 2013-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01544751
Nonalcoholic Fatty Liver Disease (NAFLD) Pharmacological Treatment: Metformin Versus Atorvastatin
Not yet reported Prof Antonino Belfiore 150 participants Est. completion 2015-06 1 siteMASLDView official trial listing → -
Completed NCT NCT01545388
Metformin Add-on Regimen Comparison Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431A-136)
Not yet reported Merck Sharp & Dohme LLC 337 participants Est. completion 2013-03-12 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01546558
Single Cohort, 2-Period Study to Assess Pharmacokinetics of Metformin Alone and in Combination With Ranolazine 500 mg
Not yet reported Gilead Sciences 25 participants Est. completion 2012-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01546597
Single Cohort 4-period Study to Assess Pharmacokinetics of Metformin Alone and in Combination With Ranolazine
Not yet reported Gilead Sciences 24 participants Est. completion 2012-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01547104
Effect of Linagliptin in Comparison With Glimepiride as Add on to Metformin on Postprandial Beta Cell Function, Postprandial Metabolism and Oxidative Stress in Patients With Type 2 Diabetes Mellitus
Not yet reported Marcus Borchert 40 participants Est. completion 2012-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01549964
Comparison of Fasiglifam (TAK-875) to Placebo and Sitagliptin in Combination With Metformin in Participants With Type 2 Diabetes
Not yet reported Takeda 916 participants Est. completion 2014-03 160 sites Stand-aloneOther conditions: Glycemic ControlView official trial listing → -
Withdrawn NCT NCT01550900
Prospective Trial of Metformin - Chemoprevention Role
Not yet reported M.D. Anderson Cancer CenterOther conditions: ColorectumView official trial listing → -
Completed NCT NCT01551615
A Phase I Study to Assess the Pharmacokinetics of Metformin When Administered Alone and in Combination With Vandetanib
Not yet reported Sanofi 14 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01555164
A Phase 3 Study of Ranolazine in Subjects With Type 2 Diabetes Who Are Inadequately Controlled on Metformin Alone
Not yet reported Gilead Sciences 442 participants Est. completion 2013-10 146 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01557504
A Study to Assess the Pharmacokinetics and the Ability for Pediatric Participants With Type 2 Diabetes to Swallow MK-0431A XR Tablets (MK-0431A-296)
Not yet reported Merck Sharp & Dohme LLC 25 participants Est. completion 2014-04-29 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01560481
Clinical Trial to Evaluate Safety and pK Profile of Metformin Glycinate in Healthy Volunteers
Not yet reported Laboratorios Silanes S.A. de C.V. 49 participants Est. completion 2013-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT01561482
Study of Metformin With Simvastatin for Men With Prostate Carcinoma
Not yet reported Nicholas Mitsiades Est. completion 2014-07 3 sites Stand-aloneOther conditions: Prostate CarcinomaView official trial listing → -
Completed NCT NCT01561976
Evaluation of Food Effect on the Pharmacokinetics of Sustained Release Metformin in Healthy Indian Volunteers
Not yet reported GlaxoSmithKline 30 participants Est. completion 2012-02-21Type 2 diabetesView official trial listing → -
Completed NCT NCT01563120
A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus
Not yet reported HaEmek Medical Center, Israel 108 participants Est. completion 2014-12 1 siteOther conditions: Gestational Diabetes MellitusView official trial listing → -
Status unknown NCT NCT01565096
Effect of Adding Vildagliptin on Beta Cell Function and Cardiovascular Risk Markers in Patients With Moderate Metabolic Control During Metformin Monotherapy
Not yet reported ikfe-CRO GmbH 44 participants 1 site Stand-aloneOther conditions: Diabetes Mellitus Type IIView official trial listing → -
Status unknown NCT NCT01566799
Metformin Plus Neoadjuvant Chemotherapy in Breast Cancer
Not yet reported Instituto Nacional de Cancerologia de Mexico 60 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Locally Advanced Malignant NeoplasmView official trial listing → -
Completed NCT NCT01573377
Efficacy of Metformin and Diane-35 on PCOS Patients,a Randomized, Controlled, Prospective Clinical Trial
Not yet reported Chongqing Medical University 40 participants Est. completion 2013-02 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Insulin ResistanceView official trial listing → -
Completed NCT NCT01573949
A Pilot Study: Metformin Therapy in Heart Failure Patients With Early Diabetes or at High Risk of Developing Diabetes (Pre-Diabetes)
Not yet reported University of California, Los Angeles 7 participants Est. completion 2012-12 1 site Stand-aloneHeart failure Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01576328
Safety Study of Mesenchymal Precursor Cells in Type 2 Diabetes
Not yet reported, Not yet reported Mesoblast, Ltd. 61 participants Est. completion 2015-10 18 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT01578551
Study of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 25 participants Est. completion 2017-01 2 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell Lung, Lung AdenocarcinomaView official trial listing → -
Completed NCT NCT01579812
Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic Patients
Not yet reported University of Michigan Rogel Cancer Center 90 participants Est. completion 2017-07 1 site Stand-aloneOther conditions: Ovarian, Fallopian Tube, and Primary Peritoneal CancerView official trial listing → -
Completed NCT NCT01581814
Effects of Drospirenone-ethinylestradiol and/or Metformin on Cardiovascular Risk in Hyperinsulinemic Women With Polycystic Ovary Syndrome
Not yet reported Catholic University of the Sacred Heart 99 participants Est. completion 2012-03 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01581931
Bioequivalence of Metformin Under Fed Conditions After Administration of Linagliptin / Metformin Fixed Dose Combination Tablet and Single Tablets
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01582230
Efficacy and Safety of Vildagliptin 50mg Bid as an add-on Therapy to Insulin With or Without Metformin, in Patients With Type 2 Diabetes Mellitus
Not yet reported Novartis Pharmaceuticals 293 participants Est. completion 2013-05 21 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01582243
Safety and Efficacy of Vildagliptin Plus Metformin (SPC) Treatment in Type 2 Diabetes Mellitus Patients
Not yet reported Novartis Pharmaceuticals 40 participants Est. completion 2015-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01584232
A Study of Dulaglutide in Japanese Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 361 participants Est. completion 2013-07 15 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01587378
Metformin to Prevent Late Miscarriage and Preterm Delivery in Women With Polycystic Ovary Syndrome
Not yet reported Norwegian University of Science and Technology 489 participants Est. completion 2017-10-31 13 sites Stand-aloneOther conditions: Pregnancy, Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01589367
Neoadjuvant Letrozole Plus Metformin vs Letrozole Plus Placebo for ER-positive Postmenopausal Breast Cancer
Not yet reported Seoul National University Hospital 208 participants Est. completion 2018-08 1 site Stand-aloneOther conditions: Hormone Receptor Positive Malignant Neoplasm of BreastView official trial listing → -
Completed NCT NCT01589445
Efficacy Study of Pioglitazone and Metformin and Association Between Pioglitazone Response and Peroxisome Proliferator-activated Receptor Gamma Gene Variants in Bangladeshi Type 2 Diabetes Mellitus Subjects
Not yet reported University of Dhaka 77 participants Est. completion 2010-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01589653
Comparing Patient-adjusted Versus Physician-adjusted Titration of BIAsp 30 Combined With Metformin in Type 2 Diabetes Patients
Not yet reported Novo Nordisk A/S 155 participants Est. completion 2015-07-09 15 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01590771
A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Sulfonylurea With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-253)
Not yet reported Merck Sharp & Dohme LLC 498 participants Est. completion 2014-06-24 Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01593137
A Long-term Trial to Compare the Effects of Liraglutide and Sulphonylurea (Glimepiride) Both in Combination With Metformin on Clinical, Endothelial and Image Markers of Cardiovascular Risk in Patients With Type 2 Diabetes
Not yet reported Fundación Fernández-Cruz Est. completion 2014-12 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01593371
Comparison of Metformin and Pioglitazone Effects on Adipokines Concentrations in Newly Diagnosed Type 2 Diabetes Patients
Not yet reported Tehran University of Medical Sciences 98 participants Est. completion 2012-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01594697
Metformin in Pregnancy in Women With Polycystic Ovary Syndrome
Not yet reported Catholic University of the Sacred Heart 60 participants 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01595789
The Effect of Liraglutide on the Treatment of Coronary Artery Disease and Type 2 Diabetes
Not yet reported Haugaard, Steen Bendix, M.D., DMSc 41 participants Est. completion 2015-07 1 siteCardiovascular diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT01595880
BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 500mg in Comparison to Each Component Administered Alone
Not yet reported LG Life Sciences 29 participants Est. completion 2015-01 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01596504
Pharmacodynamic Effects of Lixisenatide Compared to Liraglutide in Patients With Type 2 Diabetes Not Adequately Controlled With Insulin Glargine With or Without Metformin
Not yet reported Sanofi 142 participants Est. completion 2013-07 8 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01602003
Phase III Trial to Evaluate the Efficacy and Safety of LC15-0444 Compared With Sitagliptin Added to Ongoing Metformin Therapy in Patients With Type 2 Diabetes
Not yet reported LG Life Sciences 425 participants Est. completion 2012-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01604213
Effects of Vildagliptin/Metformin Combination on Markers of Atherosclerosis, Thrombosis, and Inflammation in Diabetics With Coronary Artery Disease
Not yet reported Sheba Medical Center 60 participants Est. completion 2016-04 1 site Stand-aloneType 2 diabetes Other conditions: Ischemic Heart DiseaseView official trial listing → -
Completed NCT NCT01606007
Safety and Efficacy of Combination Saxagliptin & Dapagliflozin Added to Metformin to Treat Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 1282 participants Est. completion 2014-01 139 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01610401
The Metformin-FMD Trial
Not yet reported Radboud University Medical Center 26 participants Est. completion 2013-01 1 siteOther conditions: Ischemia Reperfusion Injury, Endothelial FunctionView official trial listing → -
Completed NCT NCT01612741
Diabetes Treatment With Glucobay in Combination With Metformin
Bayer 19509 participants Est. completion 2009-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01612858
Metabolic Abnormalities in HIV-infected Persons
Not yet reported Tufts Medical Center 20 participants Est. completion 2014-11 1 site Stand-aloneOther conditions: Lipodystrophy, HIV InfectionView official trial listing → -
Completed NCT NCT01613755
Metformin-Dipyridamole Interaction Trial
Not yet reported Radboud University Medical Center 18 participants Est. completion 2012-07 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01617434
The Effect of Liraglutide Versus Placebo When Added to Basal Insulin Analogues With or Without Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 451 participants Est. completion 2013-10 86 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01618162
The Efficacy of Insulin Degludec/Liraglutide as add-on Therapy in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on Sulphonylurea With or Without Metformin Therapy
Not yet reported Novo Nordisk A/S 435 participants Est. completion 2013-10-23 87 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01619059
Safety and Efficacy of Saxagliptin in Triple Therapy to Treat Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 315 participants Est. completion 2015-01 83 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01620593
Castration Compared to Castration Plus Metformin as First Line Treatment for Patients With Advanced Prostate Cancer
Not yet reported The University of Texas Health Science Center at San Antonio 41 participants Est. completion 2016-09 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT01622257
Cavitation Ultrasound in Treatment of Patients With PCOS
Not yet reported Ain Shams University 198 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: PCOSView official trial listing → -
Completed NCT NCT01624116
Comparison of Hypoglycaemic Regimens During Ramadan Fasting in Type 2 Diabetes
Not yet reported Services Hospital, Lahore 161 participants Est. completion 2011-09 1 siteOther conditions: Diabetes, Type 2View official trial listing → -
Completed NCT NCT01624259
A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes
Not yet reported Eli Lilly and Company 599 participants Est. completion 2013-11 57 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01627067
Exemestane-RAD001-Metformin
Not yet reported M.D. Anderson Cancer Center 23 participants Est. completion 2019-02-01 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT01632020
Effect of Metformin on Biomarkers of Colorectal Tumor Cell Growth
Not yet reported University of Arkansas 7 participants Est. completion 2015-01 2 sitesOther conditions: Colorectal NeoplasmsView official trial listing → -
Completed NCT NCT01632163
Assessment of the Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Insufficiently Controlled With Basal Insulin +/- Metformin
Not yet reported Sanofi 447 participants Est. completion 2015-05 51 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Withdrawn NCT NCT01638988
Clomifene Citrate Versus Metformin in First-line Treatment of Infertility in Patients With Polycystic Ovary Syndrome and a Resistance to Insulin
Not yet reported Clinique Ovo Est. completion 2015-12 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Insulin ResistanceView official trial listing → -
Completed NCT NCT01646320
Safety and Efficacy of Dapagliflozin in Triple Therapy to Treat Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 320 participants Est. completion 2015-02 66 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01648582
A Study Comparing the Effects and Safety of Dulaglutide With Insulin Glargine in Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 774 participants Est. completion 2014-12 30 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01649297
A 16 Weeks Study on Efficacy and Safety of Two Doses of Empagliflozin (BI 10773) (Once Daily Versus Twice Daily) in Patients With Type 2 Diabetes Mellitus and Preexisting Metformin Therapy
Not yet reported Boehringer Ingelheim 983 participants Est. completion 2013-12 139 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01650181
Effects of Siliphos-Selenium-Methionine-Alpha Lipoic Acid in Patients With Fatty Liver and Non-alcoholic Steatohepatitis
Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 50 participants Est. completion 2014-06 1 siteOther conditions: Liver DiseaseView official trial listing → -
Completed NCT NCT01650506
Study of Erlotinib and Metformin in Triple Negative Breast Cancer
Not yet reported Columbia University 8 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT01654640
The Effect of Metformin on Obesity and Metabolic Disturbance in Patients Taking Clozapine
Not yet reported Seoul National University Hospital 15 participants Est. completion 2015-04 1 site Stand-aloneOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT01656057
The Impact of Gall Bladder Emptying and Bile Acids on the Human GLP-1-secretion
Not yet reported Filip Krag Knop 10 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: To Assess the Impact of Bile Acids on Human Glukagon-like-peptide-1 SecretionView official trial listing → -
Completed NCT NCT01658501
Phase 2b Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM
Not yet reported PhaseBio Pharmaceuticals Inc. 593 participants Est. completion 2013-07 93 sites MixedType 2 diabetesView official trial listing → -
Completed NCT NCT01658514
Assessing the Behavior of Met DR in Subjects With Kidney Dysfunction
Not yet reported Elcelyx Therapeutics, Inc. 39 participants Est. completion 2014-06 Stand-aloneOther conditions: Renal InsufficiencyView official trial listing → -
Completed NCT NCT01662674
BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone
Not yet reported LG Life Sciences 27 participants Est. completion 2013-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01664247
The Effect of Insulin Degludec in Combination With Liraglutide and Metformin in Subjects With Type 2 Diabetes Qualifying for Treatment Intensification
Not yet reported Novo Nordisk A/S 346 participants Est. completion 2013-12-31 132 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01664624
Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 Diabetes
Not yet reported AstraZeneca 40 participants Est. completion 2012-11 2 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01664845
Effects of Metformin, Pegylated Interferon Alpha and Ribavirin for Chronic Hepatitis C With Insulin Resistance
Not yet reported, Not yet reported Kaohsiung Veterans General Hospital. 120 participants Est. completion 2014-08 1 siteOther conditions: Chronic Hepatitis c, Insulin ResistanceView official trial listing → -
Completed NCT NCT01665352
A Study to Evaluate Safety and Efficacy of TTP054 for 12 Weeks in Subjects With Type 2 Diabetes
Not yet reported vTv Therapeutics 186 participants Est. completion 2013-05 19 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01666171
Studying Changes in Breast Density in Patients With Early-Stage Breast Cancer Treated With Metformin Hydrochloride or Placebo on CAN-NCIC-MA.32
Cancer and Leukemia Group B 458 participantsOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT01666665
Mechanisms of Improved Wound Healing and Protein Synthesis of Insulin and Metformin
Not yet reported, Not yet reported The University of Texas Medical Branch, Galveston 36 participants Est. completion 2019-04-23 1 siteOther conditions: Insulin Resistance, Hypermetabolism, HyperglycemiaView official trial listing → -
Completed NCT NCT01666730
Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer
Not yet reported Case Comprehensive Cancer Center 50 participants Est. completion 2018-08-01 2 sites Stand-aloneOther conditions: Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage IV Pancreatic CancerView official trial listing → -
Completed NCT NCT01672788
Demonstration of Bioequivalence of Empagliflozin and Metformin Given in One Tablet Compared to the Intake of Single Tablets
Not yet reported Boehringer Ingelheim 36 participants Est. completion 2012-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT01674348
A Clinical Trial to Study the Efficacy, Safety, Tolerability and Pharmacokinetics of P2202 in Patients of Type 2 Diabetes
Not yet reported Piramal Enterprises Limited 48 participants Est. completion 2013-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01675310
Medical Nutrition Therapy Plus Transgestational Metformin For Preventing Gestational Diabetes In High Risk Mexican Women
Not yet reported Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes 90 participants Est. completion 2015-03 1 site Stand-aloneOther conditions: Pregestational Obesity (BMI > 27kg/m2), History of Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01677260
Bioequivalence Study of Two Formulations of 500 mg Metformin Extended Release Tablet
Not yet reported Dexa Medica Group 38 participants Est. completion 2010-01 1 site Stand-aloneOther conditions: Metformin XR BE Study in Healthy Volunteers With Single and Multiple DoseView official trial listing → -
Completed NCT NCT01677299
Assessing the PK and Effect on Glucose and GI Hormone Concentrations of Metformin Delayed-Release in Subjects With T2DM
Not yet reported, Not yet reported Elcelyx Therapeutics, Inc. 24 participants Est. completion 2012-09 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01677897
Impact of the Addition of Metformin to Abiraterone in Metastatic Prostate Cancer Patients
Not yet reported Kantonsspital Graubünden 25 participants Est. completion 2018-06 1 site Stand-aloneOther conditions: Metastatic Prostate CancerView official trial listing → -
Completed NCT NCT01677923
Obesity in Children and Adolescents: Associated Risks and Early Intervention
Not yet reported Lithuanian University of Health Sciences 182 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Terminated NCT NCT01678820
A Study of the Efficacy and Safety of MK-0431D (a Fixed-dose Combination of Sitagliptin and Simvastatin) for the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-266)
Not yet reported Merck Sharp & Dohme LLC 299 participants Est. completion 2013-11-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01679574
Letrozole or Combined Clomiphene Citrate Metformin as a First Line Treatment in Women With Polycystic Ovarian Syndrome
Not yet reported Assiut University 200 participants Est. completion 2012-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01681693
Effect of Genetic Variants in MATE1 and OCT3 on the Pharmacodynamics of Metformin in African Americans
Not yet reported University of California, San Francisco 33 participants Est. completion 2013-07 1 site Stand-aloneType 2 diabetes Other conditions: HealthyView official trial listing → -
Completed NCT NCT01682759
A Study of the Safety and Efficacy of Omarigliptin (MK-3102) Compared With Glimepiride in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-016)
Not yet reported Merck Sharp & Dohme LLC 751 participants Est. completion 2015-01-26 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01685762
Metformin for the Treatment of Endometrial Hyperplasia
Not yet reported UNC Lineberger Comprehensive Cancer Center 18 participants Est. completion 2015-12-01 3 sites Stand-aloneOther conditions: Endometrial Hyperplasia, Endometrial Hyperplasia Without AtypiaView official trial listing → -
Active, not recruiting NCT NCT01686126
Improving the Treatment for Women With Early Stage Cancer of the Uterus
Not yet reported Queensland Centre for Gynaecological Cancer 165 participants Est. completion 2026-12 17 sites Stand-aloneOther conditions: Complex Endometrial Hyperplasia With Atypia, Grade 1 Endometrial Endometrioid AdenocarcinomaView official trial listing → -
Completed NCT NCT01690091
Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes
Not yet reported, Not yet reported Institute for Clinical and Experimental Medicine 40 participants Est. completion 2016-12 1 site Stand-aloneHeart failure Other conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT01691846
A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Alone
Not yet reported Hoffmann-La Roche 200 participants Est. completion 2013-09 31 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01691989
A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Sulfonylurea Alone or Sulfonylurea Plus Metformin Therapy
Not yet reported Hoffmann-La Roche 197 participants Est. completion 2013-09 28 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01693289
Study to Compare Between Combimed Metformin-letrozole and Ovarian Drilling in Pcos With Bilateral Ovarian Drilling in Clomiphene-resistant Infertile Women With Polycystic Ovarian Syndrome
Not yet reported Zagazig University 146 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Focus of StudyView official trial listing → -
Completed NCT NCT01697566
An Endometrial Cancer Chemoprevention Study of Metformin
Not yet reported M.D. Anderson Cancer Center 29 participants Est. completion 2024-05-30 1 site Stand-aloneOther conditions: GynecologyView official trial listing → -
Completed NCT NCT01697592
Omarigliptin (MK-3102) Clinical Trial - Add-on to Oral Antihyperglycemic Agent Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-3102-015)
Not yet reported Merck Sharp & Dohme LLC 585 participants Est. completion 2014-05-08 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01699932
Efficacy and Safety of the Fixed Dose Combination of Glimepiride+Metformin in Type 2 Diabetic Patients Inadequately Controlled
Not yet reported Sanofi 167 participants Est. completion 2014-04 13 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01700075
Physical and Chemical Study of Atherosclerosis Mechanisms
Not yet reported Nazarbayev University 97 participants Est. completion 2011-12 1 siteCardiovascular diseaseType 2 diabetes Other conditions: Atherosclerosis of Femoral ArteryView official trial listing → -
Completed NCT NCT01702298
A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)
Not yet reported Merck Sharp & Dohme LLC 42 participants Est. completion 2013-05-29 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01704261
Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Combination Therapy With Glimepiride and Metformin (MK-3102-022)
Not yet reported Merck Sharp & Dohme LLC 307 participants Est. completion 2014-12-23 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01708902
Study to Compare the Efficacy and Safety of Administration of the Fix Dose Combination of Linagliptin Plus Metformin in Drug naïve Type 2 Patients
Not yet reported Boehringer Ingelheim 876 participants Est. completion 2014-04 56 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01709305
A Study of the Safety and Efficacy of Glimepiride, Gliclazide, Repaglinide or Acarbose When Added to Sitagliptin + Metformin Combination Therapy in Chinese Participants With Diabetes (MK-0431-313)
Not yet reported Merck Sharp & Dohme LLC 5570 participants Est. completion 2015-04-17 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01710527
BE Study of Metformin GSK 500mg
Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-05-18Other conditions: Diabetic FootView official trial listing → -
Completed NCT NCT01710540
BE Study of Metformin GSK 850mg
Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-08Other conditions: Diabetic FootView official trial listing → -
Completed NCT NCT01710553
BE STUDY OF METFORMIN GSK 1000mg
Not yet reported GlaxoSmithKline 32 participants Est. completion 2012-07Other conditions: Diabetic FootView official trial listing → -
Completed NCT NCT01711320
Effect of Omeprazole on Metformin
Not yet reported Xijing Hospital 20 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT01717482
Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer
Not yet reported Mayo Clinic 6 participants Est. completion 2019-05-22 1 siteOther conditions: Lung Neoplasms, Carcinoma, Non-Small-Cell LungView official trial listing → -
Status unknown NCT NCT01717911
ß-Cell Function and Glycemic Control in Newly Diagnosed Type 2 Diabetic Patients With Moderate Hyperglycemia
Not yet reported Taipei Veterans General Hospital, Taiwan 160 participants Est. completion 2018-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01718093
A Pilot Study to Assess the Glucose Lowering Effect of Metformin and Sitagliptin in Adolescents With Type 1 Diabetes
Not yet reported Baylor College of Medicine 21 participants Est. completion 2015-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Withdrawn NCT NCT01718340
Effectiveness of Metformin in Recurrent Miscarriage in a Woman With Hyperinsulinaemia
Not yet reported Woman's Health University Hospital, Egypt Est. completion 2014-06 1 site Stand-aloneOther conditions: Abortion, HabitualView official trial listing → -
Completed NCT NCT01719003
Safety and Efficacy Study of Empagliflozin and Metformin for 24 Weeks in Treatment Naive Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 1413 participants Est. completion 2014-12 190 sites Stand-aloneType 2 diabetes Other conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT01719614
A Study to Explore Pharmacokinetic Interaction Between Rilpivirine and Metformin in Healthy Participants
Not yet reported Janssen R&D Ireland 20 participants Est. completion 2013-01 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT01720290
Comparison of Repaglinide and Metformin Administered Alone or in Combination in Type 2 Diabetes
Not yet reported Novo Nordisk A/S 150 participants Est. completion 2003-02-25 3 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01725126
To Investigate the Safety, Tolerability and Pharmacodynamics of GSK2890457 in Healthy Volunteers and Subjects With Type 2 Diabetes
Not yet reported GlaxoSmithKline 53 participants Est. completion 2013-09-12 3 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT01725490
The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study
Not yet reported Yonsei University 34 participants Est. completion 2020-08-30 1 site Stand-aloneOther conditions: Familial Adenomatous PolyposisView official trial listing → -
Terminated NCT NCT01725672
Crossover Study to Evaluate the Comparative Bioavailability of Two Fixed Dose Combination Tablet Formulations of Extended Release Metformin and Extended Release Glimepiride in Health Volunteers
Not yet reported GlaxoSmithKline 20 participants Est. completion 2013-08-21 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01726764
Interaction Between St John's Wort and Metformin?
Not yet reported University of Southern Denmark 20 participants Est. completion 2014-05 1 site Stand-aloneType 2 diabetes Other conditions: DepressionView official trial listing → -
Completed NCT NCT01728740
Bioequivalence Study for Acarbose / Metformin FDC
Not yet reported Bayer 40 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT01729156
Effects of Metformin on Hepatic FFA Metabolism
Not yet reported Lars Christian Gormsen 36 participants Est. completion 2017-05-05Type 2 diabetes Other conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT01729403
A Study of The Effect of Aleglitazar on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin
Not yet reported Hoffmann-La Roche 57 participants Est. completion 2013-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01733459
Efficacy and Safety of DLBS3233 in Subjects With Polycystic Ovary Syndrome (PCOS)
Not yet reported Dexa Medica Group 124 participants Est. completion 2018-06 2 sites Stand-aloneOther conditions: Polycystic Ovary Syndrome (PCOS)View official trial listing → -
Withdrawn NCT NCT01733836
Prostate Cancer Active Surveillance Metformin Trial
Not yet reported University Health Network, Toronto Est. completion 2014-10 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT01734785
Safety and Efficacy of the Combination of Empagliflozin and Linagliptin Compared to Linagliptin Alone Over 24 Weeks in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 607 participants Est. completion 2015-03-23 90 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01747083
Food-Effect Bioavailability Study of FDC(Gemigliptin/Metformin HCl Sustained Release) 50/1000mg(25/500mg x 2tablets)
Not yet reported LG Life Sciences 24 participants Est. completion 2013-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01751321
Glucose Variability With DPP-4 Inhibition
Not yet reported Research Clinical Centre of the Russian Railways, JSC 50 participants Est. completion 2013-10Type 2 diabetesView official trial listing → -
Completed NCT NCT01754142
Korean Post-marketing Surveillance for Kombiglyze XR®
AstraZeneca 755 participants Est. completion 2016-09-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01755156
A Study to Evaluate the Safety, Tolerability, and Efficacy of the Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Therapy (MK-3102-024)
Not yet reported Merck Sharp & Dohme LLC 402 participants Est. completion 2016-03-16 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01755468
Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Pilot Study)
Not yet reported Mount Sinai Hospital, Canada 24 participants Est. completion 2017-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01755494
A Bioequivalence Study of the Fixed Dose Combinations of Saxagliptin/Metformin XR Relative to Co-Administration
Not yet reported AstraZeneca 64 participants Est. completion 2013-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01756105
Efficacy of Metformin in Achieving Glycaemia Goals as Recommended for the Treatment of Gestational Diabetes in Non Obese Women
Not yet reported University Hospital, Strasbourg, France 84 participants Est. completion 2018-06 5 sites Stand-aloneOther conditions: Gestational Diabetes, Metformin, Treatment, Oxidative StressView official trial listing → -
Completed NCT NCT01756417
A Study to Investigate Whether Pharmacokinetic and Pharmacodynamic Interactions Exist Between Metformin and Canagliflozin (JNJ-28431754) in Healthy Volunteers
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 18 participants Est. completion 2007-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01757587
Galvus (Vildagliptin) vs Placebo in Combination With Metformin and Insulin
Not yet reported Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète 39 participants Est. completion 2015-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01759823
Bone Marrow Derived Stem Cell Transplantation in T2DM
Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2015-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01760447
A Pooled Analysis of the Safety and Efficacy of MK-0431A and MK-0431A XR in Pediatric Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin) (MK-0431A-170/MK-0431A-289)
Not yet reported Merck Sharp & Dohme LLC 223 participants Est. completion 2019-09-17 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01762046
Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans
Not yet reported Massachusetts General Hospital 1033 participants Est. completion 2025-12 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01763346
Beta Cell Restoration Through Fat Mitigation
Not yet reported University of Southern California 88 participants Est. completion 2018-06 1 sitePrediabetesType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT01765894
Influence of Moderate Exercise on Blood Glucose in Type 2 Diabetics and Healthy Controls
University of Copenhagen 24 participants Est. completion 2013-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01765946
Metformin and Longevity Genes in Prediabetes
Not yet reported University of Padova 38 participants Est. completion 2013-03 1 site Stand-alonePrediabetes Other conditions: Insulin Resistance, Aging, InflammationView official trial listing → -
Completed NCT NCT01766778
Early add-on Vildagliptin in Patients With Type 2 Diabetes Inadequately Controlled by Metformin
Not yet reported Novartis Pharmaceuticals 117 participants Est. completion 2015-10-22 4 sitesOther conditions: Type-2 Diabetes MellitusView official trial listing → -
Completed NCT NCT01767389
Glucagon-like Peptide (GLP) Utilization and Safety
GlaxoSmithKline 1 participants Est. completion 2013-12Type 2 diabetesView official trial listing → -
Completed NCT NCT01768559
Efficacy and Safety of Lixisenatide Versus Insulin Glulisine on Top of Insulin Glargine With or Without Metformin in Type 2 Diabetic Patients
Not yet reported Sanofi 894 participants Est. completion 2014-12 199 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT01771185
Metabolic Effects of Gastrointestinal Surgery in T2DM
Not yet reported University of Sao Paulo 24 participants Est. completion 2013-12Type 2 diabetesView official trial listing → -
Completed NCT NCT01775579
Evaluating a Pharmacokinetic Drug Interaction Between Metformin Hydrochloride and Rosuvastatin Calcium
Not yet reported Hanmi Pharmaceutical Company Limited 36 participants Est. completion 2013-06 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01775813
The Health Influences of Puberty (HIP) Study
Not yet reported University of Colorado, Denver 104 participants Est. completion 2018-05-31 1 site Stand-aloneType 2 diabetes Other conditions: Obesity, Insulin Resistance, Gonadal DysfunctionView official trial listing → -
Completed NCT NCT01778049
Linagliptin as Add on Therapy to Empagliflozin 10 mg or 25 mg With Background Metformin in Patient With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 708 participants Est. completion 2015-03 114 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01778244
Metformin for Treatment of Antipsychotic-induced Dyslipidemia
Not yet reported Central South University 162 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT01779362
RISE Adult Medication Study
Not yet reported RISE Study Group 267 participants Est. completion 2019-08 4 sitesPrediabetesType 2 diabetesView official trial listing → -
Completed NCT NCT01779375
RISE Pediatric Medication Study
Not yet reported RISE Study Group 91 participants Est. completion 2018-04 4 sitesPrediabetesType 2 diabetesView official trial listing → -
Completed NCT NCT01780051
A Pharmacokinetic Study to Compare Co-administration of Repaglinide and Metformin HCl to Administration of Combination Preparation of Those Two Components
Not yet reported Dalim BioTech Co., Ltd. 48 participants Est. completion 2013-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01781754
Changes in Mitochondrial Uncoupling Protein 2 (UCP2) Messenger RNA(mRNA) in Type 2 Diabetes (T2DM) Patients
Tel-Aviv Sourasky Medical Center 50 participants Est. completion 2014-01 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01784380
The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome
Zhongshan Bo Ai Hospital 1159 participants Est. completion 2012-10 2 sitesOther conditions: The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;, At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;, 534 Patients in the Cases Group and 580 Women in the Control Group Received no Measures, While 579 Patients Received Drugs;, The Investigators Monitored Basic Indexes in Blood of All the Subjects in This Suvey,and Also Monitored Indexes of 579 Patients After Treatment.View official trial listing → -
Completed NCT NCT01785043
Differences in Endothelial Function Amongst Sitagliptin and Liraglutide Users
Not yet reported Anna Cruceta 13 participants Est. completion 2014-09 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01786707
Autologous Stem Cell and Hyperbaric Oxygen Therapy in Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Rodolfo Alejandro 2 participants Est. completion 2013-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01787396
Phase III Trial to Evaluate the Efficacy and Safety of Initial Combination Therapy With Gemigliptin 50mg q.d and Metformin q.d
Not yet reported LG Life Sciences 433 participants Est. completion 2015-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01789957
Extension Study for 2993-112
Not yet reported AstraZeneca 225 participants Est. completion 2004-06 226 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01791647
Myo-inositol Versus Metformin in Obese Women With Polycystic Ovary Syndrome
Not yet reported Catholic University of the Sacred Heart 40 participants Est. completion 2012-12 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01792830
Efficacy and Safety of a Glargine-based Hospital Discharge Algorithm in Coronary Artery Bypass Graft (CABG) Patients
Not yet reported Emory University 175 participants Est. completion 2014-02 3 sitesOther conditions: Poor Glycemic ControlView official trial listing → -
Completed NCT NCT01796028
Metformin-Docetaxel Association in Metastatic Hormone-refractory Prostate Cancer
Not yet reported Centre Antoine Lacassagne 100 participants Est. completion 2018-05-31 1 site Stand-aloneOther conditions: Prostatic NeoplasmsView official trial listing → -
Completed NCT NCT01797523
A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma
Not yet reported M.D. Anderson Cancer Center 62 participants Est. completion 2026-02-04 6 sites Stand-aloneOther conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT01798706
Efficacy and Safety of Lixisenatide Versus Placebo on Top of Basal Insulin and/or Oral Antidiabetic Treatment in Older Type 2 Diabetic Patients
Not yet reported Sanofi 350 participants Est. completion 2015-02 83 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT01798875
PCOS, Therapy and Markers of Cardiovascular Risk
Not yet reported Medical University of Gdansk 50 participants Est. completion 2015-12 1 siteOther conditions: PCOSView official trial listing → -
Terminated NCT NCT01799057
The Effects of Metformin on Functional Capacity in Individuals With Peripheral Artery Disease-Related Intermittent Claudication
Not yet reported Baker Heart and Diabetes Institute 2 participants Est. completion 2014-12 1 site Stand-aloneAlcohol use disorder Other conditions: Peripheral Arterial DiseaseView official trial listing → -
Completed NCT NCT01800227
Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fasting Conditions
Not yet reported Torrent Pharmaceuticals Limited 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01800240
Bioequivalence Study of Torrent Pharmaceuticals Ltd's Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets Under Fed Conditions
Not yet reported Torrent Pharmaceuticals Limited 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01804049
Metformin and Muscle in Insulin-resistant Older Veterans
Not yet reported, Not yet reported VA Office of Research and Development 120 participants Est. completion 2018-08-31 1 sitePrediabetesView official trial listing → -
Completed NCT NCT01804842
Assessing the Effect of Met DR on Plasma Glucose and PK in Subjects With T2DM
Not yet reported, Not yet reported Elcelyx Therapeutics, Inc. 26 participants Est. completion 2013-04 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01809327
A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise
Not yet reported Janssen Research & Development, LLC 1186 participants Est. completion 2014-12-02 129 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01811485
Study of Efficacy and Safety LMF237 in Patients With Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Vildagliptin Monotherapy
Not yet reported Novartis Pharmaceuticals 171 participants Est. completion 2014-02 30 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01811953
Equivalence of Resorption of Empagliflozin/Metformin Administered as Combination Tablet Compared With Empagliflozin/Metformin as Single Tablets Administered Together
Not yet reported Boehringer Ingelheim 48 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01813929
Effect of Metformin on Vascular and Mitochondrial Function in Type 1 Diabetes
Not yet reported University of Colorado, Denver 23 participants Est. completion 2017-03-24 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01814748
A Study of the Safety and Efficacy of Omarigliptin (MK-3102) in ≥18 and <45 Year-Old Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control (MK-3102-028)
Not yet reported Merck Sharp & Dohme LLC 203 participants Est. completion 2015-09-14 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT01816659
An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin
Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2014-08 1 site Stand-aloneOther conditions: Colorectal CarcinomaView official trial listing → -
Terminated NCT NCT01817777
An Open Study to Evaluate Whether Pack Size Affects Compliance of Metformin Treatment in Subjects With Type II Diabetes
Not yet reported GlaxoSmithKline 31 participants Est. completion 2014-02 7 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01819129
Efficacy and Safety of FIAsp Compared to Insulin Aspart in Combination With Insulin Glargine and Metformin in Adults With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 881 participants Est. completion 2015-01-22 144 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01819272
Assessing the Efficacy, Safety, and Tolerability of Met DR in Subjects With T2DM Over 12 Weeks
Not yet reported Elcelyx Therapeutics, Inc. 240 participants Est. completion 2013-09 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01822548
Effect of Vildagliptin vs. Glibenclamide on Circulating Endothelial Progenitor Cell Number Type 2 Diabetes
Not yet reported Azienda Ospedaliero-Universitaria di Parma 64 participants Est. completion 2015-01 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01825798
Treatment of Overweight Induced by Antipsychotic Medication in Young People With Autism Spectrum Disorders (ASD)
Not yet reported Holland Bloorview Kids Rehabilitation Hospital 60 participants Est. completion 2015-10 4 sites Stand-aloneOther conditions: Overweight, Autism Spectrum DisorderView official trial listing → -
Completed NCT NCT01827280
Acute and Short-term Chronic Effects of Galvus (Vildagliptin) in Diabetes Type 2 Obese Women
Not yet reported Rio de Janeiro State University 40 participants Est. completion 2016-11 1 site Stand-aloneOther conditions: 1- Microvascular Function, 2-oxidative Stress, 3-inflammationView official trial listing → -
Completed NCT NCT01831661
Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fasting Condition
Not yet reported IPCA Laboratories Ltd. 48 participants Est. completion 2013-02 1 site Stand-aloneOther conditions: FastingView official trial listing → -
Completed NCT NCT01831674
Bioequivalence Study of Metformin Hydrochloride Extended-Release Tablets USP 750 mg Under Fed Condition
Not yet reported IPCA Laboratories Ltd. 48 participants Est. completion 2013-02 1 site Stand-aloneOther conditions: FastingView official trial listing → -
Completed NCT NCT01832181
MiTy Kids (Metformin in Women With Type 2 Diabetes in Pregnancy Kids Trial)
Mount Sinai Hospital, Canada 287 participants Est. completion 2021-05 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT01834274
Comparison of Fasiglifam (TAK-875) With Sitagliptin When Used in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Takeda 96 participants Est. completion 2014-03 104 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01840007
Pilot Study Evaluating the Efficacy and Safety of Metformin in Melanoma
Not yet reported Centre Hospitalier Universitaire de Nice 20 participants Est. completion 2015-11-18 2 sites Stand-aloneOther conditions: Metastatic Melanoma (Stage IIIC Non-résécable or no Surgically Curable or Stage IV With Classification AJCC)View official trial listing → -
Completed NCT NCT01841697
Study to Evaluate the Safety and Efficacy of the Addition of Omarigliptin (MK-3102) Compared With the Addition of Sitagliptin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-026)
Not yet reported Merck Sharp & Dohme LLC 642 participants Est. completion 2014-11-17 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01842620
OXEMET™ 1000 mg Coated Tablets (Metformin Hydrochloride) Bioequivalence Study. OXEMET (TM) is a Trademark of the GlaxoSmithKline Group of Companies. GLAFORNIL(TM) is a Trademark of Merck.
Not yet reported GlaxoSmithKline 25 participants Est. completion 2013-05-04 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01844531
Bioequivalence of Empagliflozin and Metformin Given as a Fixed Dose Combination Compared to Single Tablets
Not yet reported Boehringer Ingelheim 24 participants Est. completion 2013-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01845077
Relative Bioavailability of 2 Fixed Dose Combinations of Linagliptin/Metformin Compared With Single Tablets
Not yet reported Boehringer Ingelheim 72 participants Est. completion 2013-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01845831
Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes
Not yet reported Emory University 292 participants Est. completion 2016-04 5 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01849276
Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML
Not yet reported Northwestern University 2 participants Est. completion 2016-01-21 1 site Stand-aloneOther conditions: Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Erythroleukemia (M6a), Adult Pure Erythroid Leukemia (M6b), Blastic Phase Chronic Myelogenous Leukemia, Recurrent Adult Acute Myeloid Leukemia, Untreated Adult Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01849289
A Trial Comparing Efficacy and Safety of Insulin Degludec and Insulin Glargine in Insulin naïve Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 833 participants Est. completion 2014-05-15 81 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01850615
Efficacy and Safety of FIAsp in a Basal-bolus Regimen Versus Basal Insulin Therapy, Both in Combination With Metformin in Adult Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 323 participants Est. completion 2014-11-17 58 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT01855763
Metformin Treatment in Gestational Diabetes and Noninsulin Dependent Diabetes in Pregnancy in a Developing Country
Not yet reported, Not yet reported Dow University of Health Sciences 300 participants Est. completion 2013-12 Stand-aloneType 2 diabetes Other conditions: Gestational Diabetes, PregnancyView official trial listing → -
Completed NCT NCT01856907
Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM
Not yet reported Woman's 36 participants Est. completion 2017-09-28 1 site Stand-aloneOther conditions: Disorder of Glucose RegulationView official trial listing → -
Completed NCT NCT01857609
Clinical Trial to Investigate the Effect of Proton Pump Inhibitor on the Pharmacokinetics and Pharmacodynamics of Metformin
Not yet reported Seoul National University Hospital 24 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01859793
Effects of Sitagliptin on Endothelial Function in Type 2 Diabetes on Background Metformin Therapy
Not yet reported Medical College of Wisconsin 38 participants Est. completion 2016-07 1 siteOther conditions: Diabetes, AtherosclerosisView official trial listing → -
Terminated NCT NCT01863667
A Study to Evaluate the Safety and Efficacy of Omarigliptin (MK-3102) Compared With Glimepiride in Participants With Type 2 Diabetes Mellitus for Whom Metformin is Inappropriate (MK-3102-027)
Not yet reported Merck Sharp & Dohme LLC 65 participants Est. completion 2014-04-03Type 2 diabetesView official trial listing → -
Status unknown NCT NCT01864096
The Metformin Active Surveillance Trial (MAST) Study
Not yet reported University Health Network, Toronto 408 participants Est. completion 2024-08 12 sites Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT01864174
Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes
Not yet reported Bristol-Myers Squibb 1736 participants Est. completion 2016-06-01 156 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01864681
Combination of Metformin With Gefitinib to Treat NSCLC
Not yet reported Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 224 participants Est. completion 2018-06-04 1 site Stand-aloneOther conditions: NSCLC, EGFR Gene Amplification, Advanced Cancer, Stage IIIB NSCLC, Stage IV NSCLCView official trial listing → -
Completed NCT NCT01866462
Pilot Study of the Effect of MN-504 Cobiotic Formulation on the Efficacy and Tolerability of Metformin
Not yet reported NuMe Health 10 participants Est. completion 2014-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01867502
Effects of Vildagliptin Versus Glibenclamide on Glycemia After Exercise in Patients With Type 2 Diabetes
Not yet reported Hospital de Clinicas de Porto Alegre 20 participants Est. completion 2015-08 1 siteType 2 diabetes Other conditions: Hypoglycemic Agents, Diabetic Blood Glucose Monitoring, ExerciseView official trial listing → -
Completed NCT NCT01868542
A Trial Comparing the Glycaemic Control of Levemir® Administered Once Daily According to Two Insulin Detemir Titration Algorithms After 20 Weeks in Subjects With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin Treatment With or Without Other Anti-diabetic Drugs (OADs)
Not yet reported Novo Nordisk A/S 46 participants Est. completion 2015-05 6 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01869621
Study of Metformin Pharmacogenetics in Twins
Not yet reported University of Southern Denmark 34 participants Est. completion 2014-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01871415
A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy
Not yet reported Hoffmann-La Roche 7 participants Est. completion 2013-08 7 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01871558
Vildagliptin/Metformin in T2DM Patients Starting Basal Insulin
Not yet reported Novartis Pharmaceuticals 42 participants Est. completion 2015-02 19 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01874080
Bioequivalence Study
Not yet reported AstraZeneca 56 participants Est. completion 2013-07 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Terminated NCT NCT01876992
Metformin at the Cellular Level and Dosing for Diabetes Mellitus (DM)
Not yet reported Johns Hopkins University 10 participants Est. completion 2015-06 1 site Stand-alonePrediabetes Other conditions: Diabetes, ObesityView official trial listing → -
Completed NCT NCT01877564
A Randomized Pilot Study to Evaluate the Effects of a Short Course of Metformin Versus No Therapy in the Period Prior to Hysterectomy for Grade 1-2 Adenocarcinoma of the Endometrium in Obese Non-Diabetic Women
Not yet reported University of Arkansas 10 participants Est. completion 2017-07-10 1 site Stand-aloneOther conditions: Adenocarcinoma of the EndometriumView official trial listing → -
Completed NCT NCT01879293
Metformin Reduces Left Ventricular Mass in Patients With Ischemic Heart Disease
Not yet reported Wuhan General Hospital of Guangzhou Military Command 120 participants Est. completion 2015-08 1 site Stand-aloneOther conditions: Left Ventriclar MassView official trial listing → -
Completed NCT NCT01881828
Metformin Therapy for Overweight Adolescents With Type 1 Diabetes
Not yet reported Jaeb Center for Health Research 164 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01882907
Safety and Efficacy Study to Compare Vildagliptin to Pioglitazone as Adding on Metformin in Type 2 Diabetes
Not yet reported Pusan National University Hospital 287 participants Est. completion 2013-03 15 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01884558
A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Metformin
Not yet reported Astellas Pharma Global Development, Inc. 24 participants Est. completion 2013-02 1 site Stand-aloneOther conditions: Pharmacokinetics of Isavuconazole, Pharmacokinetics of Metformin, Healthy SubjectsView official trial listing → -
Completed NCT NCT01885013
Myocet + Cyclophosphamide + Metformin Vs Myocet + Cyclophosphamide in 1st Line Treatment of HER2 Neg. Metastatic Breast Cancer Patients
Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 126 participants Est. completion 2015-05 25 sites Stand-aloneOther conditions: Human Epidermal Growth Factor 2 Negative Carcinoma of BreastView official trial listing → -
Completed NCT NCT01885260
Safety, Tolerability and Efficacy of ISIS-GCGRRx in Type 2 Diabetes
Not yet reported Ionis Pharmaceuticals, Inc. 77 participants Est. completion 2014-11 24 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01889667
Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Oral Bedtime Doses of ORMD-0801 in Adult Patients With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Oramed, Ltd. 30 participants Est. completion 2013-11 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT01889706
Metformin Therapy in Type 1 Diabetes Mellitus.
Poznan University of Medical Sciences 200 participants Est. completion 2014-02 1 siteOther conditions: Loss of Control of DiabetesView official trial listing → -
Completed NCT NCT01890122
Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 Diabetes
Not yet reported Takeda 647 participants Est. completion 2015-10 45 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01890629
Effects of Gemigliptin Versus Sitagliptin or Glimepiride With Metformin on Glucose Variability(MAGE, Glucose SD) Patients With Type 2 DM(STABLE Study)
Not yet reported LG Life Sciences 69 participants Est. completion 2014-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01892020
Investigating Efficacy and Safety of Biphasic Insulin Aspart 50 Twice Daily Versus Biphasic Human Insulin 50 Twice Daily Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 161 participants Est. completion 2014-05 1 site Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01892254
Incretin Effect in PCOS Women
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2017-11-23 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT01895569
Triple Therapy in Type 2 Diabetic Patients
Not yet reported University of Pavia 64 participants Est. completion 2016-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01899430
Polycystic Ovary Syndrome and Liraglutide
Not yet reported University Medical Centre Ljubljana 32 participants Est. completion 2013-04 1 siteOther conditions: PCOS, ObesityView official trial listing → -
Terminated NCT NCT01901224
Metformin, Muscle Energetics, and Vascular Function in Older Adults With Peripheral Artery Disease
Not yet reported Brigham and Women's Hospital 2 participants Est. completion 2015-06 1 site Stand-aloneOther conditions: Peripheral Artery DiseaseView official trial listing → -
Completed NCT NCT01903356
A Regulatory Requirement Non Interventional Study to Monitor Safety and Effectiveness of Trajenta Duo in Type 2 Diabetes Patients in Korea
Boehringer Ingelheim 724 participants Est. completion 2017-06-10 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT01905046
Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer
Not yet reported Alliance for Clinical Trials in Oncology 86 participants Est. completion 2026-11 27 sites Stand-aloneOther conditions: Atypical Ductal Breast Hyperplasia, BRCA1 Mutation Carrier, BRCA2 Mutation Carrier, Ductal Breast Carcinoma in Situ, Lobular Breast Carcinoma in SituView official trial listing → -
Completed NCT NCT01907854
Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin
Not yet reported Novo Nordisk A/S 407 participants Est. completion 2015-06-15 106 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01909141
Ovulation Induction in Women With Clomiphene Citrate Resistant PCOS
Not yet reported Cairo University 100 participants Est. completion 2014-04 1 siteOther conditions: Polycystic Ovary Syndrome, InfertilityView official trial listing → -
Withdrawn NCT NCT01910246
Cardiovascular Effects of Metformin on Obesity
Not yet reported University of California, San Francisco Est. completion 2016-10 1 site Stand-aloneOther conditions: Insulin ResistanceView official trial listing → -
Terminated NCT NCT01910441
Comparison of Vildagliptin vs. Glimepiride on Glucose Variability in Metformin Uncontrolled Type 2 Diabetic Patients
Not yet reported Novartis Pharmaceuticals 95 participants Est. completion 2014-09 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01911468
Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin
Not yet reported University Medical Centre Ljubljana 36 participants Est. completion 2013-04 1 siteOther conditions: PCOS, ObesityView official trial listing → -
Withdrawn NCT NCT01915264
GLucobay M - Evaluation Of Safety and Effectiveness in Type 2 Diabetes Not Well Controlled on Monotherapy in Real Life Practice
Bayer Est. completion 2017-03Type 2 diabetesView official trial listing → -
Completed NCT NCT01915550
Metformin as Adjuvant to Insulin Therapy in Insulin-resistant Diabetes Mellitus With Pregnancy
Not yet reported Ain Shams University 90 participants Est. completion 2013-02 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01917656
Efficacy and Safety of Liraglutide Versus Sulphonylurea Both in Combination With Metformin During Ramadan in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 343 participants Est. completion 2014-09-04 41 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01918865
Safety, Tolerability, and Efficacy of ISIS-PTP1BRx in Type 2 Diabetes
Not yet reported Ionis Pharmaceuticals, Inc. 92 participants Est. completion 2015-02 21 sites Stand-aloneType 2 diabetes Other conditions: ObeseView official trial listing → -
Completed NCT NCT01923181
Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 632 participants Est. completion 2014-12-11 103 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT01926769
A Phase II Study to Determine the Safety and Efficacy of Second-line Treatment With Metformin and Chemotherapy (FOLFOX6 or FOFIRI) in the Second Line Threatment of Advanced Colorectal Cancer
Not yet reported Gachon University Gil Medical Center 2 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Previously Treated Advanced Colorectal CancerView official trial listing → -
Completed NCT NCT01929512
Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 750mg and Rosuvastatin 20mg
Not yet reported Hanmi Pharmaceutical Company Limited 72 participants Est. completion 2013-08 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT01929811
NeoMET Study in Neoadjuvant Treatment of Breast Cancer
Not yet reported Shanghai Jiao Tong University School of Medicine 92 participants Est. completion 2020-06 2 sites Stand-aloneOther conditions: pCR Rate, BCT Rate, SafetyView official trial listing → -
Completed NCT NCT01929863
Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 in Type 2 Diabetes Patients Taking Metformin
Not yet reported GlaxoSmithKline 16 participants Est. completion 2013-11-21 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01930188
Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin and/or TZD in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1231 participants Est. completion 2015-10-12 141 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT01930864
Metformin Plus Irinotecan for Refractory Colorectal Cancer
Not yet reported Barretos Cancer Hospital 41 participants Est. completion 2020-12-01 2 sites Stand-aloneOther conditions: Colorectal Neoplasms, AdenocarcinomaView official trial listing → -
Completed NCT NCT01933256
Study of Subcutaneous Doses of HIP2B in Subjects With Type 2 Diabetes Mellitus Treated With Metformin
Not yet reported CureDM 32 participants Est. completion 2014-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01933672
Study Of Two Dosing Regimens Of PF-04937319 Compared To An Approved Agent (Sitagliptin) In Patients With Type 2 Diabetes
Not yet reported Pfizer 33 participants Est. completion 2014-03 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01935804
Effect of Pioglitazone Versus Metformin on Bone Health in Postmenopausal Women With Type 2 Diabetes
Not yet reported King Abdulaziz University 440 participants Est. completion 2014-01 1 siteType 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT01937598
Antidiabetic Effects of Adding a DPP-4 Inhibitor to Pre-Existing Treatment With an Incretin Mimetic in Patients With T2D
Not yet reported Michael A. Nauck 16 participants Est. completion 2015-06 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT01940302
Dietary Supplement of LEHEL for the Patients With Type 2 Diabetes
Not yet reported Shaoguan University 71 participants Est. completion 2014-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT01944618
forREAL: FORXIGA PRESCRIPTION EVENT MONITORING PROGRAM (PEMP)
AstraZeneca 5000 participants Est. completion 2015-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01947153
Two-way Crossover Study in Healthy Male and Female Subjects to Evaluate the Bioequivalence of Jentadueto®.
Not yet reported Boehringer Ingelheim 36 participants Est. completion 2014-01 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01947790
Pioglitazone Regress Left Ventricular Mass in Type 2 Diabetes With Ischeamia Heart Disease
Not yet reported Xiang Guang-da 120 participants Est. completion 2015-07 2 sitesOther conditions: LVM, Type 2 Diabetic Patients With IHD, Endothelial FunctionView official trial listing → -
Withdrawn NCT NCT01951183
A Study of RO6811135 in Patients With Type 2 Diabetes Who Are Inadequately Controlled With Metformin
Not yet reported Hoffmann-La Roche Est. completion 2013-12Type 2 diabetesView official trial listing → -
Completed NCT NCT01952145
A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide Versus Insulin Glargine in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 557 participants Est. completion 2014-11-04 91 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Withdrawn NCT NCT01954732
Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery
Not yet reported Case Comprehensive Cancer Center Est. completion 2015-03 Stand-aloneOther conditions: Stage IA Pancreatic Cancer, Stage IB Pancreatic Cancer, Stage IIA Pancreatic Cancer, Stage IIB Pancreatic CancerView official trial listing → -
Completed NCT NCT01956305
Randomized, Placebo-controlled, 2 Period, Single-blind, Sequential, Multiple Ascending Dose Study
Not yet reported Daiichi Sankyo 48 participants Est. completion 2014-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01956929
Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism.
Not yet reported Mayo Clinic 12 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: Insulin Resistance, Prediabetic StateView official trial listing → -
Completed NCT NCT01958671
A Study of the Efficacy and Safety of Ertugliflozin Monotherapy in the Treatment of Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control Despite Diet and Exercise (MK-8835-003, VERTIS MONO)
Not yet reported Merck Sharp & Dohme LLC 461 participants Est. completion 2016-07-28 Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01961388
Study to Assess the Dietary Carbohydrate Content of Indian Diabetics With Special Therapeutic View on Effectiveness of Acarbose and Metformin Monotherapy
Bayer Est. completion 2017-06Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01963130
Does Vildagliptin Affect Portal Vein Pressure In Patients With Type 2 Diabetes Mellitus? A Cross Sectional Study
Bezmialem Vakif University 97 participants Est. completion 2013-07 1 siteOther conditions: Drug Mechanism, Drug UsageView official trial listing → -
Completed NCT NCT01963663
Metformin and Pioglitazone Effects on YKL-40 Concentrations in Type 2 Diabetes Patients
Not yet reported Tehran University of Medical Sciences 84 participants Est. completion 2013-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01965509
A PK/PD Study of Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 120 participants Est. completion 2013-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01965756
Effect of Insulin Sensitizer Metformin on AD Biomarkers
Not yet reported University of Pennsylvania 20 participants Est. completion 2017-04 1 site Stand-aloneOther conditions: Alzheimer's Disease, Vascular Dementia, Dementia, Memory ImpairmentView official trial listing → -
Completed NCT NCT01966978
The Effect of Simple Basal Insulin Titration, Metformin Plus Liraglutide for Type 2 Diabetes With Very Elevated HbA1c - The SIMPLE Study
Not yet reported University of Texas Southwestern Medical Center 157 participants Est. completion 2017-12 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01968265
Safety, Tolerability and Efficacy of ISIS-GCCRRx in Type 2 Diabetes
Not yet reported Ionis Pharmaceuticals, Inc. 38 participants Est. completion 2015-05 14 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01968317
Megestrol Acetate Plus Metformin to Megestrol Acetate in Patients With Endometrial Atypical Hyperplasia or Early Stage Endometrial Adenocarcinoma
Not yet reported Xiaojun Chen 150 participants Est. completion 2017-10 5 sites Stand-aloneOther conditions: Endometrial Atypical Hyperplasia, Endometrial AdenocarcinomaView official trial listing → -
Completed NCT NCT01969318
Efficacy and Safety Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 120 participants Est. completion 2012-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT01970046
A Phase III Study of SP2086 in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 360 participants Est. completion 2015-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01971034
Treatment of Patients With Advanced Pancreatic Cancer After Gemcitabine Failure.
Not yet reported Instituto do Cancer do Estado de São Paulo 41 participants 1 site Stand-aloneOther conditions: Pancreatic Adenocarcinoma Advanced or MetastaticView official trial listing → -
Completed NCT NCT01972724
Efficacy of Pioglitazone in Participants With Inadequately Controlled Type 2 Diabetes Mellitus Treated With Stable Triple Oral Therapy
Not yet reported Takeda 114 participants Est. completion 2016-10-17 9 sites Stand-aloneOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT01973231
Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 404 participants Est. completion 2014-11 61 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01973933
Clinical Trial to Investigate the Pharmacokinetic/Pharmacodynamic Drug-Drug Interaction of Pyrimethamine and Metformin IR
Not yet reported Seoul National University Hospital 20 participants 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01974544
Prevention and Treatment Of Diabetes Complications With Gastric Surgery or Intensive Medicines
Not yet reported Pontificia Universidad Catolica de Chile 150 participants Est. completion 2016-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01980823
Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer
Not yet reported Columbia University 23 participants Est. completion 2022-12 1 site Stand-aloneOther conditions: Breast Cancer, Breast Tumors, Cancer of BreastView official trial listing → -
Completed NCT NCT01981525
A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome
Not yet reported National Cancer Institute (NCI) 26 participants Est. completion 2020-12-11 1 site Stand-aloneOther conditions: Li-Fraumeni SyndromeView official trial listing → -
Completed NCT NCT01984489
Efficacy and Safety Study of SHR117887 in Combination With Metformin in Patients With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 120 participants Est. completion 2013-08 Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01984606
Efficacy and Safety of Empagliflozin Versus Sitagliptin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim Est. completion 2017-02Type 2 diabetesView official trial listing → -
Completed NCT NCT01990469
Efficacy and Safety of Gemigliptin 50mg qd Added in Patients With Type 2 Diabetes Inadequately Controlled on Glimepiride and Metformin
Not yet reported LG Life Sciences 219 participants Est. completion 2015-04Type 2 diabetesView official trial listing → -
Completed NCT NCT01992211
Evaluating of Pharmacokinetic Profile of BCWP_C003 and Co-administration of Rosuvastatin and Metformin
Not yet reported BC World Pharm Co. Ltd. 35 participants Est. completion 2017-07-10 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01995032
L-citrulline and Metformin in Duchenne's Muscular Dystrophy
Not yet reported University Hospital, Basel, Switzerland 47 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: Duchenne's Muscular Dystrophy (DMD)View official trial listing → -
Terminated NCT NCT01996696
Prevention of Metabolic Syndrome and Increased Weight Using Metformin Concurrent to Androgen Deprivation Therapy and Radiotherapy for Locally Advanced Adenocarcinoma of the Prostate
Not yet reported AHS Cancer Control Alberta 83 participants Est. completion 2020-11 3 sites Stand-aloneOther conditions: Prostatic NeoplasmView official trial listing → -
Terminated NCT NCT01997775
Metformin in Stage IV Lung Adenocarcinoma
Not yet reported National Cheng-Kung University Hospital 13 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT01998113
Glyburide and Metformin for the Treatment of Gestational Diabetes Mellitus. Systematic Review
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 2509 participants Est. completion 2014-05 1 siteOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT01999218
Ertugliflozin vs. Glimepiride in Type 2 Diabetes Mellitus (T2DM) Participants on Metformin (MK-8835-002)
Not yet reported Merck Sharp & Dohme LLC 1326 participants Est. completion 2017-04-18 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01999686
PCOS Treatment Using DLBS3233, Metformin, and Combination of Both
Not yet reported Dexa Medica Group 186 participants Est. completion 2019-05 7 sites Stand-aloneOther conditions: Polycystic Ovary Syndrome (PCOS), Insulin ResistanceView official trial listing → -
Completed NCT NCT02002221
Study of Efficacy and Safety of Vildagliptin as add-on Insulin Therapy in T2DM Patients
Not yet reported Novartis Pharmaceuticals 156 participants Est. completion 2015-02 31 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02004886
A Study to Assess the Safety, Tolerability and Glucose-Lowering Efficacy of MK-0893 in Participants With Type 2 Diabetes Mellitus (MK-0893-005)
Not yet reported Merck Sharp & Dohme LLC 74 participants Est. completion 2007-02-07 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02005419
Metformin Combined With Gemcitabine as Adjuvant Therapy for Pancreatic Cancer After Curative Resection
Not yet reported Xian-Jun Yu 300 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: Stage IA Pancreatic Adenocarcinoma, Stage IB Pancreatic Adenocarcinoma, Stage IIA Pancreatic Adenocarcinoma, Stage IIB Pancreatic AdenocarcinomaView official trial listing → -
Completed NCT NCT02006836
Glycemic Responses to Majia Pomelos in Type 2 Diabetic Patients
Not yet reported Huazhong University of Science and Technology 59 participants Est. completion 2013-12 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02007278
Glycemic Excursions in Type 2 Diabetic Patients With Vildagliptin and Metformin Versus Vildagliptin and Glimepiride
Not yet reported Novartis Pharmaceuticals 40 participants Est. completion 2016-02-22 8 sitesType 2 diabetes Other conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02008682
The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 368 participants Est. completion 2014-11 25 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02009488
Treatment Differences Between Canagliflozin and Placebo in Insulin Secretion in Subjects With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Janssen Research & Development, LLC 59 participants Est. completion 2017-01-03 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02011633
Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 500mg and Rosuvastatin 10mg
Not yet reported Hanmi Pharmaceutical Company Limited 72 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02014740
Effect of Liraglutide on Epicardial Fat in Subjects With Type 2 Diabetes
Not yet reported University of Miami 100 participants Est. completion 2017-03 1 site Added to GLP-1Type 2 diabetes Other conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT02017561
Metformin in the Diastolic Dysfunction of Metabolic Syndrome
Not yet reported Universidade do Porto 54 participants Est. completion 2019-12 1 site Stand-aloneMetabolic syndrome Other conditions: Diastolic Dysfunction, Insulin ResistanceView official trial listing → -
Completed NCT NCT02018731
L-citrulline and Metformin in Becker's Muscular Dystrophy
Not yet reported University Hospital, Basel, Switzerland 20 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: Becker's Muscular Dystrophy (BMD)View official trial listing → -
Terminated NCT NCT02019979
Metformin and Carbohydrate Restriction With Platinum Based Chemotherapy In Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NS-NSCLC)
Not yet reported Beth Israel Medical Center 14 participants Est. completion 2016-12 4 sites Stand-aloneOther conditions: Non-small Cell Lung Cancer Stage IIIB/IV, Non-small Cell Lung Cancer Metastatic, Nonsquamous Nonsmall Cell Neoplasm of LungView official trial listing → -
Terminated NCT NCT02020616
A Study of the Safety and Effectiveness of LY3053102 in Participants With Type 2 Diabetes
Not yet reported, Not yet reported Eli Lilly and Company 60 participants Est. completion 2015-02 5 sites MixedType 2 diabetesView official trial listing → -
Completed NCT NCT02022007
Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis
Not yet reported Woman's 38 participants Est. completion 2016-10 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Disorder of Glucose RegulationView official trial listing → -
Completed NCT NCT02022254
Influence of Semaglutide on Pharmacokinetics and Pharmacodynamics of Warfarin and Pharmacokinetics of Metformin in Healthy Subjects
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2014-08-28 1 site Added to GLP-1Type 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT02024971
Special Drug Use Surveillance of Pioglitazone/Metformin Hydrochloride Combination Tablets Survey on Long-term Use for Type 2 Diabetes Mellitus
Takeda 1103 participants Est. completion 2013-11Type 2 diabetesView official trial listing → -
Completed NCT NCT02025907
A Study to Evaluate the Efficacy and Safety of the Addition of Canagliflozin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin and Sitagliptin
Not yet reported Janssen Research & Development, LLC 218 participants Est. completion 2015-09 57 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02026310
Efficacy/Safety Study of Glimepiride to Type 2 Diabetes Patients Based on Metformin And Basal Insulin Treatment
Not yet reported Qifu Li 40 participants Est. completion 2015-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02026817
Comparison of PK After Administration of HCP1201 and Co-administration of Metformin SR 750mg and Rosuvastatin 10mg
Not yet reported Hanmi Pharmaceutical Company Limited 36 participants Est. completion 2014-01 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT02026869
Vaginal Administration of Metformin in PCOS Patients.
Not yet reported Assiut University 200 participants Est. completion 2014-02 1 siteOther conditions: PCOSView official trial listing → -
Completed NCT NCT02027103
Metformin and Pioglitazone Effects on Fetuin-A and Osteoprotegrin Concentrations in Type 2 Diabetes Patients
Not yet reported Tehran University of Medical Sciences 102 participants Est. completion 2012-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02027753
Efficacy and Safety of Insulin Glargine in Patients With Type 2 Diabetes With Inadequate Control on DPP-4 Inhibitor Therapy
Not yet reported Sanofi 109 participants Est. completion 2015-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02028221
Phase II Study of Metformin for Reduction of Obesity-Associated Breast Cancer Risk
Not yet reported University of Arizona 151 participants Est. completion 2022-06-14 1 site Stand-aloneOther conditions: Breast Cancer PreventionView official trial listing → -
Completed NCT NCT02028689
Metformin and Furosemide Drug-Drug Interaction Study
Not yet reported Ardea Biosciences, Inc. 23 participants Est. completion 2014-01 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02028767
Bioequivalence Study in Healthy Volunteers for Empagliflozin/Metformin Fixed Dose Combination Compared to Separate Tablets
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2014-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT02029846
Glycemia in Diabetic Elders Trial
Not yet reported Johns Hopkins University 2 participants Est. completion 2017-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02033876
Ursodiol on Insulin Sensitivity, Gastric Emptying and Body Weight With Type 2 Diabetes on Metformin
Not yet reported Mayo Clinic 24 participants Est. completion 2017-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02033889
A Study To Evaluate The Efficacy And Safety Of Ertugliflozin In Participants With Type 2 Diabetes Mellitus And Inadequate Glycemic Control On Metformin Monotherapy (MK-8835-007).
Not yet reported Merck Sharp & Dohme LLC 621 participants Est. completion 2017-08-03 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02035787
Metformin With the Levonorgestrel-Releasing Intrauterine Device for the Treatment of Complex Atypical Hyperplasia (CAH) and Endometrial Cancer (EC) in Non-surgical Patients
Not yet reported UNC Lineberger Comprehensive Cancer Center 20 participants Est. completion 2024-04-12 2 sites Stand-aloneOther conditions: Complex Atypical Hyperplasia, Endometrial CancerView official trial listing → -
Completed NCT NCT02036515
Safety and Efficacy of Ertugliflozin in the Treatment of Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin (MK-8835-006; VERTIS SITA2)
Not yet reported Merck Sharp & Dohme LLC 464 participants Est. completion 2016-06-06 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02037672
PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome
Not yet reported University Medical Centre Ljubljana 36 participants Est. completion 2014-01 1 siteOther conditions: PCOS, ObesityView official trial listing → -
Completed NCT NCT02039245
Multiple Dose Pharmacokinetics of Canagliflozin/Metformin 150/1,000 mg Fixed Dose Combination
Not yet reported Janssen Research & Development, LLC 12 participants Est. completion 2014-03 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02039258
Pharmacokinetics of a Fixed Dose Combination of Canagliflozin/Metformin Coadministered With Food
Not yet reported Janssen Research & Development, LLC 24 participants Est. completion 2014-03 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02040246
Comparison of Metformin and Repaglinide Monotherapy in the Treatment of New Onset Type 2 Diabetes Mellitus in China
Not yet reported RenJi Hospital 107 participants Est. completion 2014-01 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02040376
Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma
Not yet reported The Hospital for Sick Children 24 participants Est. completion 2017-12-15 1 site Stand-aloneOther conditions: Brain Tumor Treated With Cranial or Cranial-Spinal RadiationView official trial listing → -
Withdrawn NCT NCT02042495
Endometrial Cancer Biomarker Changes Following Exposure to Metformin
Not yet reported Jewish General Hospital 1 site Stand-aloneOther conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT02042664
Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese Diabetics
Not yet reported Assistance Publique Hopitaux De Marseille 44 participants Est. completion 2015-06 1 siteOther conditions: Obesity, DiabetesView official trial listing → -
Completed NCT NCT02045290
Insulin Clamp Ancillary Study for Assessment of Insulin Resistance
Not yet reported Jaeb Center for Health Research 37 participants Est. completion 2016-02-15 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02048384
A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 22 participants Est. completion 2019-09 2 sites Stand-aloneOther conditions: Metastatic Pancreatic AdenocarcinomaView official trial listing → -
Status unknown NCT NCT02048761
Locally Delivered 1% Metformin Gel in the Treatment of Intrabony Defects in Chronic Periodontitis
Not yet reported Government Dental College and Research Institute, Bangalore 65 participants Est. completion 2014-02 1 siteOther conditions: Intrabony Defects in Chronic PeriodontitisView official trial listing → -
Completed NCT NCT02049034
Lixisenatide-The Effects on Glucose and Lipid Metabolism in Type 2 Diabetes
Not yet reported University of Surrey 8 participants Est. completion 2016-01 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Withdrawn NCT NCT02050009
Metformin Hydrochloride, Carboplatin, and Paclitaxel in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Not yet reported Fox Chase Cancer Center Est. completion 2014-10-31 1 site Stand-aloneOther conditions: Ovarian Papillary Serous Carcinoma, Ovarian Serous Cystadenocarcinoma, Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Primary Peritoneal Cavity CancerView official trial listing → -
Completed NCT NCT02050074
The Role of Metformin and Colesevelam in Human GLP-1 Secretion
Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2014-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02051842
Effect of Metadoxine on Oxidative Stress in Non-alcoholic Hepatic Steatosis
Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 100 participants Est. completion 2020-12 1 site Stand-aloneMASLDPrediabetesView official trial listing → -
Completed NCT NCT02052011
Ranolazine and Microvascular Angina by PET in the Emergency Department
Not yet reported Yale University 31 participants Est. completion 2015-11 1 site Stand-aloneOther conditions: Microvascular AnginaView official trial listing → -
Terminated NCT NCT02053103
A 6-Week Study To Determine The Safety And Effect Of An Investigational Drug On Adults With Type 2 Diabetes Mellitus Taking Metformin
Not yet reported Pfizer 13 participants Est. completion 2014-04 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT02053116
A 6-Week Study To Determine The Safety And Effect Of An Investigational Drug Given With Canagliflozin In Adults With Type 2 Diabetes Mellitus Taking Metformin
Not yet reported Pfizer 8 participants Est. completion 2014-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02053272
A Study of GWP42004 as Add on to Metformin in the Treatment of Participants With Type 2 Diabetes
Not yet reported Jazz Pharmaceuticals 207 participants Est. completion 2016-02 25 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02056600
BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 1000mg in Comparison to Each Component Administered Alone.
Not yet reported LG Life Sciences 24 participants Est. completion 2014-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02058147
Efficacy and Safety of Insulin Glargine/ Lixisenatide Fixed Ratio Combination Compared to Insulin Glargine Alone and Lixisenatide Alone on Top of Metformin in Patients With T2DM
Not yet reported Sanofi 1170 participants Est. completion 2015-06 273 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02058160
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes
Not yet reported Sanofi 736 participants Est. completion 2015-07 236 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02060383
Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or Acromegaly
Not yet reported Novartis Pharmaceuticals 249 participants Est. completion 2018-03-26 43 sites MixedOther conditions: Cushing's Disease, AcromegalyView official trial listing → -
Completed NCT NCT02061969
ADA Linagliptin in Long Term Care
Not yet reported Emory University 140 participants Est. completion 2017-04-10 4 sites Stand-aloneOther conditions: DiabetesView official trial listing → -
Status unknown NCT NCT02063802
Metformin vs Conjugated Linoleic Acid and an Intervention Program With Healthy Habits in Obese Children
Not yet reported Laboratorios Silanes S.A. de C.V. 120 participants Est. completion 2014-05 1 siteOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT02064881
Efficacy Study of Metformin Glycinate on Postprandial Lipemia
Not yet reported, Not yet reported Laboratorios Silanes S.A. de C.V. 72 participants Est. completion 2020-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02065687
Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer
Not yet reported, Not yet reported Gynecologic Oncology Group 469 participants Est. completion 2023-09-13 431 sites Stand-aloneOther conditions: Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Endometrial Undifferentiated Carcinoma, Recurrent Uterine Corpus Carcinoma, Stage III Uterine Corpus Cancer AJCC v7, Stage IIIA Uterine Corpus Cancer AJCC v7, Stage IIIB Uterine Corpus Cancer AJCC v7, Stage IIIC Uterine Corpus Cancer AJCC v7, Stage IV Uterine Corpus Cancer AJCC v7, Stage IVA Uterine Corpus Cancer AJCC v7, Stage IVB Uterine Corpus Cancer AJCC v7View official trial listing → -
Completed NCT NCT02065752
A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components
Not yet reported Janssen Research & Development, LLC 2 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02069379
Endogenous Opioid Activity and Affective State in Insulin Resistant Women
Not yet reported University of Michigan 42 participants Est. completion 2017-09 1 site Stand-aloneMetabolic syndrome Other conditions: Depression, Insulin ResistanceView official trial listing → -
Completed NCT NCT02071368
A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants
Not yet reported Janssen Research & Development, LLC 3 participants Est. completion 2014-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT02072096
A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Eli Lilly and Company 192 participants Est. completion 2015-10 34 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT02072382
The Hypotensive Effect of Metformin in Hypertensive Patients.
Not yet reported Hospital de Clinicas de Porto Alegre 92 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: HypertensionView official trial listing → -
Completed NCT NCT02073227
A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components
Not yet reported Janssen Research & Development, LLC 52 participants Est. completion 2014-06 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02076347
Comparison of Two Pharmacist-led Population Management Approaches to Increase Monitoring of Vitamin B12 and Serum Creatinine Levels for Patients on Metformin
Not yet reported Ohio State University 489 participants Est. completion 2015-10 1 siteType 2 diabetes Other conditions: Vitamin B12 Deficiency, Neuropathy, AnemiaView official trial listing → -
Completed NCT NCT02077803
A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants
Not yet reported Janssen Research & Development, LLC 47 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02080377
A Feasibility Study Looking at the Use of Glibenclamide and metfoRmin Versus stAndard Care in gEstational diabeteS
Not yet reported University of Edinburgh 23 participants Est. completion 2016-03 5 sitesOther conditions: Pregnancy, Gestational DiabetesView official trial listing → -
Completed NCT NCT02081118
Glycaemic Control of Monthly LAPS-Exendin Versus Placebo in Subjects of Type 2 Diabetes
Not yet reported Hanmi Pharmaceutical Company Limited 209 participants Est. completion 2015-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02083692
Pilot Study of Metformin in Head and Neck Squamous Cell Cancer and Its Effects on Stromal-epithelial Metabolic Uncoupling
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 50 participants Est. completion 2017-04-06 1 site Stand-aloneOther conditions: Head and Neck Squamous Cell CancerView official trial listing → -
Completed NCT NCT02084056
Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/1000mg) Extended Release in Healthy Subjects.
Not yet reported Boehringer Ingelheim 74 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02084082
Bioequivalence of a FDC Tablet of Linagliptin/Metformin (5mg/1000mg) Extended Release in Healthy Subjects
Not yet reported Boehringer Ingelheim 68 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02086526
Targeting Pathways in Polycystic Ovary Syndrome (PCOS) Using Metformin (MET)
Not yet reported Mayo Clinic 68 participants Est. completion 2016-11-20 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Active, not recruiting NCT NCT02087826
Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS
Not yet reported Massachusetts General Hospital 1017 participants Est. completion 2026-12 1 siteType 2 diabetes Other conditions: Genetics, MetabolismView official trial listing → -
Completed NCT NCT02088034
Intervention to Promote Weight Loss in Latinas At-risk for Diabetes
Not yet reported Temple University 92 participants Est. completion 2016-02 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02088918
A Open-label, Single-dose, 2-Sequence, 2-Period, Crossover Study to Assess Safety and Pharmacokinetics of a Nateglinide/Metformin HCl Combined Tablet Compared With a Nateglinide 120 mg Tablet and Metformin HCl 500 mg Tablet Under Fasting Conditions in Healthy Male Subjects
Not yet reported IlDong Pharmaceutical Co Ltd 40 participants 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT02091336
Oral Antidiabetic Agents in Pregnancy
Not yet reported Hospital de Clinicas de Porto Alegre 80 participants Est. completion 2016-12 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT02091362
A Study of LY2409021 on Blood Pressure and Pulse Rate in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 270 participants Est. completion 2015-01 30 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02097342
Effect of Linagliptin on Insulin Sensitivity and Pancreatic Beta Cell Function in Patients With Type 2 Diabetes Mellitus
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2015-01 1 siteType 2 diabetes Other conditions: Insulin Sensitivity/ResistanceView official trial listing → -
Completed NCT NCT02099110
Ertugliflozin and Sitagliptin Co-administration Factorial Study (VERTIS FACTORAL, MK-8835-005)
Not yet reported Merck Sharp & Dohme LLC 1233 participants Est. completion 2016-05-26 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02100475
A Trial Comparing Sequential Addition of Insulin Aspart Versus Further Dose Increase With Insulin Degludec/Liraglutide in Subjects With Type 2 Diabetes Mellitus, Previously Treated With Insulin Degludec/Liraglutide and Metformin and in Need of Further Intensification
Not yet reported Novo Nordisk A/S 31 participants Est. completion 2015-04 60 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02102932
Bioavailability of Empagliflozin/Metformin Fixed Dose Combinations (FDCs) in Healthy Chinese Volunteers
Not yet reported Boehringer Ingelheim 96 participants Est. completion 2014-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02104804
Evaluate the Efficacy and Safety of Saxagliptin Added to Insulin Monotherapy or to Insulin Combined With Metformin in Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control
Not yet reported AstraZeneca 953 participants Est. completion 2016-02-26 11 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02106104
Renal Effects of DPP-4 Inhibitor Linagliptin in Type 2 Diabetes
Not yet reported Amsterdam UMC, location VUmc 48 participants Est. completion 2016-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02106923
Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Extended Release (XR) Compared With Single Tablets
Not yet reported Boehringer Ingelheim 72 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02109679
Relative Bioavailability of Multiple Oral Doses of BI 187004 and Metformin After Co-administration Compared to Multiple Oral Doses of BI 187004 Alone and Metformin Alone in Healthy Male Subjects
Not yet reported Boehringer Ingelheim 16 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT02111096
A Study of LY2409021 in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 174 participants Est. completion 2015-09 33 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02111967
Study to Identify Adequate Biomarker to Detect Vitamin B12 Deficiency in Type 2 Diabetic Patients Treated With Metformin
University Hospital, Basel, Switzerland 50 participants Est. completion 2014-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02113163
PK Study Comparing Metformin Eicosapentaenoate to a Combined Dose of Metformin Hydrochloride and Ethyl Ester EPA
Not yet reported Thetis Pharmaceuticals LLC 32 participants Est. completion 2014-07 1 siteOther conditions: Diabetes Mellitus, Non-Insulin-Dependent, HypertriglyceridemiaView official trial listing → -
Terminated NCT NCT02115464
Advanced Lung Cancer Treatment With Metformin and Chemo-Radiotherapy
Not yet reported Ontario Clinical Oncology Group (OCOG) 54 participants Est. completion 2020-04-21 7 sites Stand-aloneOther conditions: Lung CancerView official trial listing → -
Completed NCT NCT02119819
A Study to Compare a New Drug for Type 2 Diabetes to Placebo and to a Treatment Already Available for Type 2 Diabetes
Not yet reported OPKO Health, Inc. 420 participants Est. completion 2015-10 51 sites MixedType 2 diabetesView official trial listing → -
Completed NCT NCT02121509
Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/750mg) Extended Release in Healthy Subjects
Not yet reported Boehringer Ingelheim 74 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02122185
Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Not yet reported University of Chicago 111 participants Est. completion 2024-10-08 10 sites Stand-aloneOther conditions: Brenner Tumor, Malignant Ascites, Malignant Pleural Effusion, Ovarian Clear Cell Cystadenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Mixed Epithelial Carcinoma, Ovarian Serous Cystadenocarcinoma, Ovarian Undifferentiated Adenocarcinoma, Recurrent Fallopian Tube Cancer, Recurrent Ovarian Epithelial Cancer, Recurrent Ovarian Germ Cell Tumor, Recurrent Primary Peritoneal Cavity Cancer, Stage IIIA Fallopian Tube Cancer, Stage IIIA Ovarian Epithelial Cancer, Stage IIIA Ovarian Germ Cell Tumor, Stage IIIA Primary Peritoneal Cavity Cancer, Stage IIIB Fallopian Tube Cancer, Stage IIIB Ovarian Epithelial Cancer, Stage IIIB Ovarian Germ Cell Tumor, Stage IIIB Primary Peritoneal Cavity Cancer, Stage IIIC Fallopian Tube Cancer, Stage IIIC Ovarian Epithelial Cancer, Stage IIIC Ovarian Germ Cell Tumor, Stage IIIC Primary Peritoneal Cavity Cancer, Stage IV Fallopian Tube Cancer, Stage IV Ovarian Epithelial Cancer, Stage IV Ovarian Germ Cell Tumor, Stage IV Primary Peritoneal Cavity CancerView official trial listing → -
Completed NCT NCT02125227
Phase 1 Clinical Trial to Investigate the Effect on the Pharmacokinetics of YH14755 Compared to Co-administration of Rosuvastatin and Metformin SR in Healthy Volunteers
Not yet reported Yuhan Corporation 56 participants Est. completion 2014-09 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02125305
Clinical Study to Investigate the Pharmacokinetics and Pharmacodynamics of Metformin in the Elderly
Not yet reported Seoul National University Hospital 12 participants 1 site Stand-aloneOther conditions: Healthy ElderlyView official trial listing → -
Completed NCT NCT02128932
Efficacy and Safety of Semaglutide Once Weekly Versus Insulin Glargine Once Daily as add-on to Metformin With or Without Sulphonylurea in Insulin-naïve Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1089 participants Est. completion 2015-09-03 231 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT02129985
Effect on Beta Cell Function and Glycaemic Control After Insulin and Exenatide Sequential Therapy
Not yet reported xiaolong zhao 100 participants Est. completion 2015-09 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT02131272
A Trial Investigating the Efficacy and Safety of Insulin Detemir Versus Insulin NPH in Combination With Metformin and Diet/Exercise in Children and Adolescents With Type 2 Diabetes Insufficiently Controlled on Metformin With or Without Other Oral Antidiabetic Drug(s) With or Without Basal Insulin
Not yet reported Novo Nordisk A/S 42 participants Est. completion 2016-06-14 82 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02133118
Weight Trajectory in New Users of Sulfonylureas as Add on Therapy Next to Metformin.
Medical Research Foundation, The Netherlands 16293 participants Est. completion 2014-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02135549
Study of the Effectiveness and Safety of SugarDown vs. Placebo in Type 2 Diabetic Subjects Treated With Metformin
Not yet reported Boston Therapeutics 24 participants Est. completion 2014-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02138097
Oral and Non-insulin Injected Hypoglycemic Therapy Utilization Patterns
Boehringer Ingelheim 615067 participants Est. completion 2014-08 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT02140788
Effects of Metformin and Fish Oil on Treatment With Clozapine
Not yet reported Duke University 34 participants Est. completion 2013-02Other conditions: Schizophrenia, Schizo-affective DisorderView official trial listing → -
Status unknown NCT NCT02142309
Glycemic Durability After Metformin Failure
Not yet reported University of Campania Luigi Vanvitelli 450 participants Est. completion 2017-01 2 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02143050
Study of Dabrafenib, Trametinib and Metformin for Melanoma Patients
Not yet reported, Not yet reported University of Louisville Est. completion 2017-11-17 2 sites Stand-aloneOther conditions: MelanomaView official trial listing → -
Completed NCT NCT02145559
A Pharmacodynamic Study of Sirolimus and Metformin in Patients With Advanced Solid Tumors
Not yet reported University of Chicago 24 participants Est. completion 2018-07 1 site Stand-aloneOther conditions: Breast Neoplasms, Lung Neoplasms, Cancer of Liver, Lymphoma, Cancer of KidneyView official trial listing → -
Completed NCT NCT02145611
Vildagliptin vs. Glibenclamide in Endothelial Function in Type 2 Diabetes and Hypertension
Not yet reported Dr. José Fernando Vilela-Martin MD PhD 50 participants Est. completion 2016-05 1 siteType 2 diabetes Other conditions: Hypertension, Endothelial DysfunctionView official trial listing → -
Completed NCT NCT02147925
Efficacy Study of Liraglutide vs.Sitagliptin vs. Glargine on Liver Fat in T2DM Subjects
Not yet reported Sun Yat-sen University 75 participants Est. completion 2017-04 1 siteOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Status unknown NCT NCT02149459
Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy
Not yet reported Sheba Medical Center 18 participants Est. completion 2018-07 1 site Stand-aloneOther conditions: Brain NeoplasmsView official trial listing → -
Completed NCT NCT02150824
Safety and Tolerability, Efficacy, Pharmacokinetic and Pharmacodynamic Study of Three Doses of BI 187004 Over 28 Days in Patients With Type 2 Diabetes Mellitus With and Without Metformin
Not yet reported Boehringer Ingelheim 103 participants Est. completion 2015-08 3 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02151461
Dose Comparisons of Leucine-Metformin Combinations on Blood Glucose Levels In Type 2 Diabetic Patients
Not yet reported NuSirt Biopharma 96 participants Est. completion 2016-01 9 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02152371
A Study of Dulaglutide (LY2189265) in Participants With Type II Diabetes
Not yet reported Eli Lilly and Company 300 participants Est. completion 2015-10 40 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02153450
Stereotactic Radiosurgery and Metformin in Patients With Borderline-Resectable or Locally-Advanced Pancreatic Cancer
Not yet reported Case Comprehensive Cancer Center 8 participants Est. completion 2020-06-13 1 site Stand-aloneOther conditions: Acinar Cell Adenocarcinoma of the Pancreas, Duct Cell Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage I-III Pancreatic CancerView official trial listing → -
Completed NCT NCT02157974
Liver and Fat Regulation in Overweight Adolescent Girls
Not yet reported, Not yet reported University of Colorado, Denver 92 participants Est. completion 2022-12 1 siteOther conditions: Hepatic Steatosis, Polycystic Ovarian Syndrome, ObesityView official trial listing → -
Completed NCT NCT02160743
The Food Effect on Pharmacokinetics and Safety of Fixed-dose Combination of CJ-30056 in Healthy Male Subjects
Not yet reported HK inno.N Corporation 28 participants Est. completion 2014-11 1 site Stand-aloneOther conditions: Food Effect Study of CJ-30056 20mg/500mgView official trial listing → -
Completed NCT NCT02167061
A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01 Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg, and to Evaluate the Effect of Food on the Pharmacokinetics of DA-1229_01 in Healthy Male Volunteers
Not yet reported Dong-A ST Co., Ltd. 64 participants Est. completion 2014-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02172248
Relative Bioavailability BI 10773 and Metformin in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 16 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02173639
Bioavailability of Combination Tablet BI 1356/Metformin Compared With Single BI 1356 and Metformin Administered Together to Healthy Male and Female Subjects
Not yet reported Boehringer Ingelheim 20 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02176161
Metformin Prostate Cancer Adjuvant Trial
Not yet reported NYU Langone Health 59 participants Est. completion 2021-07-21 1 site Stand-aloneOther conditions: Prostate Cancer, Prostate Cancer RecurrentView official trial listing → -
Completed NCT NCT02179788
Metformin to Augment Low Milk Supply (MALMS) Study
Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 15 participants Est. completion 2016-07 1 site Stand-alonePrediabetes Other conditions: Low Milk Supply, Insulin Resistance, Suppressed LactationView official trial listing → -
Completed NCT NCT02183506
Bioavailability of BI 1356 BS and Metformin After Co-administration Compared to the Bioavailability of BI 1356 BS Alone and Metformin Alone in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 16 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02183571
Bioequivalence Study of Two Strengths of Two Different Metformin Tablets Administered to Healthy Male and Female Subjects
Not yet reported Boehringer Ingelheim 56 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02183935
Treatment of Morbidly Obese Adolescent With a Duodena-jejunal Liner
Not yet reported University Medical Centre Ljubljana 22 participants Est. completion 2018-12-20 1 siteMetabolic syndrome Other conditions: Obesity, DiabetesView official trial listing → -
Completed NCT NCT02184832
Dietary Intake of Tryptophan and Metformin Response
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: Metformin Response, Fasting Glucose, Tryptophan Concentration, Metformin Concentration, Diet TolerabilityView official trial listing → -
Completed NCT NCT02186483
Clinical Trial to Investigate the Pharmacokinetics Drug Interaction Between Metformin and Rosuvastatin
Not yet reported Jeil Pharmaceutical Co., Ltd. 24 participants Est. completion 2015-02 1 site Stand-aloneOther conditions: Hyperlipidemia, DiabetesView official trial listing → -
Completed NCT NCT02186847
Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer
Not yet reported NRG Oncology 170 participants Est. completion 2025-09-04 223 sites Stand-aloneOther conditions: Adenosquamous Lung Carcinoma, Bronchioloalveolar Carcinoma, Large Cell Lung Carcinoma, Lung Adenocarcinoma, Non-Small Cell Lung Carcinoma, Recurrent Non-Small Cell Lung Carcinoma, Squamous Cell Lung Carcinoma, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02187250
PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary Syndrome
Not yet reported University Medical Centre Ljubljana 45 participants Est. completion 2014-06 1 siteOther conditions: PCOS, ObesityView official trial listing → -
Completed NCT NCT02188186
Therapeutic Efficacy of Triple Combination in Drug-naïve Korean Type 2 Diabetic Patients
Not yet reported Seoul National University Bundang Hospital 200 participants Est. completion 2018-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02188654
Metformin in Psoriatic Arthritis
Not yet reported University of Alexandria 56 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Psoriatic ArthritisView official trial listing → -
Terminated NCT NCT02190838
Comparison of Melatonin or Metformin and Dacarbazine Combination Versus Dacarbazine Alone in Disseminated Melanoma
Not yet reported N.N. Petrov National Medical Research Center of Oncology 57 participants Est. completion 2018-12-31 3 sites Stand-aloneOther conditions: MelanomaView official trial listing → -
Completed NCT NCT02192424
Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Main Trial)
Not yet reported Mount Sinai Hospital, Canada 109 participants Est. completion 2020-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02198417
Metformin Treatment in Polycystic Ovary Syndrome (PCOS)
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2020-12 Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Withdrawn NCT NCT02201381
Study of the Safety, Tolerability and Efficacy of Metabolic Combination Treatments on Cancer
Not yet reported Health Clinics Limited Est. completion 2027-09-23 1 site Stand-aloneOther conditions: Cancer, Overall SurvivalView official trial listing → -
Completed NCT NCT02202161
A Study Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2330672 Administered With Metformin to Type 2 Diabetes Patients
Not yet reported GlaxoSmithKline 70 participants Est. completion 2015-01-30 4 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02205528
A Study of Once-Daily NNC0090-2746 in Participants With Type 2 Diabetes Inadequately Controlled With Metformin
Not yet reported Novo Nordisk A/S 108 participants Est. completion 2015-09-15 20 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02206607
Study To Compare Single Dose Of Three Modified Release Formulations Of PF-04937319 With Immediate Release Material-Sparing-Tablet (IR MST) Formulation Previously Studied In Adults With Type 2 Diabetes Mellitus.
Not yet reported Pfizer 39 participants Est. completion 2015-01 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02212756
Pharmacokinetic Profiles of Metformin With DW1029M
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 12 participants Est. completion 2015-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT02217670
Comparative Bioavailability Study of Metformin HCl 1000 mg Granules vs Glucophage 1000 mg Film-coated Tablet
Not yet reported Disphar International B.V. 1 site Stand-aloneOther conditions: Comparative BioavailabilityView official trial listing → -
Completed NCT NCT02219750
Comparison of Premixed Insulin With Basal-plus Insulin in Type 2 Diabetes Patients
Not yet reported Mackay Memorial Hospital 181 participants Est. completion 2016-08 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02220218
Bioequivalence Study of Metformin Component of Canagliflozin and Metformin Fixed Dose Combination Immediate Release (IR) Tablet Comparing With Metformin IR Tablet Co-administered With Canagliflozin Tablet in Healthy Fed and Fasted Participants
Not yet reported Janssen Research & Development, LLC 2 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02220647
Bioequivalence of a 2.5 mg Linagliptin / 850 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 850 mg Tablets in Healthy Volunteers
Not yet reported Boehringer Ingelheim 96 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02221180
Bioequivalence Study of Metformin Component of Fixed Dose Combination (FDC) Immediate Release (IR) Tablet of Canagliflozin and Metformin Compared to Metformin IR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants
Not yet reported Janssen Research & Development, LLC 2 participants Est. completion 2014-11 1 site Stand-aloneOther conditions: BioequivalenceView official trial listing → -
Completed NCT NCT02221401
Bioequivalence of a Linagliptin / Metformin Fixed-dose Combination (FDC) Tablet Compared With Single Linagliptin and Metformin Tablets Administered Together in Healthy Volunteers
Not yet reported Boehringer Ingelheim 96 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02221414
Bioequivalence of a 2.5 mg Linagliptin / 500 mg Metformin Fixed Dose Combination Tablet Compared With Single Linagliptin 2.5 mg and Metformin 500 mg Tablets Administered Together in Healthy Volunteers
Not yet reported Boehringer Ingelheim 95 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02223026
Relative Bioavailability of a Linagliptin+Metformin Fixed Dose Combination Tablet Administered With and Without Food to Healthy Male and Female Subjects
Not yet reported Boehringer Ingelheim 32 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02226510
MetfoRmin and Its Effects on Left Ventricular Hypertrophy in Normotensive Patients With Coronary Artery Disease
Not yet reported University of Dundee 68 participants Est. completion 2017-12 1 siteCardiovascular diseasePrediabetes Other conditions: Left Ventricular Hypertrophy, Insulin ResistanceView official trial listing → -
Withdrawn NCT NCT02229240
Albiglutide Versus Placebo Added-on to Basal-Bolus Insulin Therapy in Subjects With Type 2 Diabetes Mellitus
Not yet reported GlaxoSmithKline Est. completion 2015-12 Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02229383
Phase III Study to Evaluate Safety and Efficacy of Added Exenatide Versus Placebo to Titrated Basal Insulin Glargine in Inadequately Controlled Patients With Type II Diabetes Mellitus
Not yet reported AstraZeneca 464 participants Est. completion 2016-08-29 123 sites Added to GLP-1Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02229396
Phase 3 28-Week Study With 24-Week and 52-week Extension Phases to Evaluate Efficacy and Safety of Exenatide Once Weekly and Dapagliflozin Versus Exenatide and Dapagliflozin Matching Placebo
Not yet reported AstraZeneca 695 participants Est. completion 2017-12-28 133 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02230995
Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Subjects
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02231021
The Practical Evidence of Antidiabetic Combination Therapy in Korea
Not yet reported Kun-Ho Yoon 216 participants Est. completion 2019-01-28 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02231931
Drug-drug Interaction Between Digoxin, Furosemide, Metformin, and Rosuvastatin
Not yet reported Boehringer Ingelheim 24 participants Est. completion 2015-01-01 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02234440
Effect of Metformin on Disease Progression in Patients With Cryptogenic Cirrhosis (NASH-related Cirrhosis) With Diabetes or Impaired Glucose Tolerance or Insulin Resistance
Not yet reported Institute of Liver and Biliary Sciences, India 86 participants Est. completion 2015-12-31 1 site Stand-aloneMASHView official trial listing → -
Completed NCT NCT02235298
Dapagliflozin Effects on Epicardial Fat
Not yet reported University of Miami 100 participants Est. completion 2020-09-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02243176
24-Week, Multicenter, Randomized, Parallel-group, Open-label, Active Controlled Phase IV Study to Assess the Efficacy, Safety and Tolerability of Saxagliptin Compared With Acarbose When in Combination With Metformin in Patients With T2D Inadequately Controlled With Metformin Monotherapy
Not yet reported AstraZeneca 689 participants Est. completion 2015-09 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT02244164
Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments.
Not yet reported Erasme University Hospital 5 participants Est. completion 2023-02-13 1 siteType 2 diabetes Other conditions: Incretinomimetics, PancreasView official trial listing → -
Status unknown NCT NCT02244567
Effect of Metformin Therapy on Serum Under-carboxylated Osteocalcin Levels in Hyperandrogenic Lean Polycystic Ovarian Syndrome Women
Not yet reported Beni-Suef University 100 participants Est. completion 2021-06 1 siteOther conditions: Polycystic Ovarian SyndromeView official trial listing → -
Status unknown NCT NCT02246257
Early Rheumatoid Arthritis COR Intervention
Not yet reported MD, PhD, Annemarie Lyng Svensson 300 participants Est. completion 2024-09 1 siteCardiovascular disease Other conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02249910
Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Metformin and Digoxin in Healthy Subjects
Not yet reported Novo Nordisk A/S 32 participants Est. completion 2015-03-06 1 site Added to GLP-1Other conditions: Diabetes, HealthyView official trial listing → -
Withdrawn NCT NCT02250794
Metformin and Sitagliptin Therapy for Adult Patients With Type 2 Diabetes Admitted to the General Medical Unit
Not yet reported Rush University Medical Center Est. completion 2015-05 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02252081
Metformin in Kidney Disease
Not yet reported VA Office of Research and Development 125 participants Est. completion 2019-12-31 1 siteChronic kidney diseaseCardiovascular diseaseMetabolic syndromeView official trial listing → -
Completed NCT NCT02252965
Metformin Extended Release Versus Metformin Immediate Release in Subjects With Type 2 Diabetes
Not yet reported Merck KGaA, Darmstadt, Germany 532 participants Est. completion 2016-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02266472
Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Male and Female
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02269098
The Synergy to Control Emergency Department Hyperglycemia Program for Type 2 Diabetes
Not yet reported Medstar Health Research Institute 101 participants Est. completion 2013-12 1 site Stand-aloneType 2 diabetes Other conditions: Medication Adherence, HYPERGLYCEMIAView official trial listing → -
Completed NCT NCT02272556
Investigating the Role of the Polyol Pathway in the Central Nervous System
Not yet reported Yale University 138 participants Est. completion 2022-05-18 1 siteOther conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT02273050
Evaluate the Efficacy and Safety of Saxagliptin in Combination With Metformin IR Compared to Saxagliptin Monotherapy and to Metformin IR Monotherapy in Drug Naive Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic Control
Not yet reported AstraZeneca 1136 participants Est. completion 2016-08 17 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02274090
1% Metformin in Moderate and Severe Periodontitis
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 70 participants Est. completion 2014-08Other conditions: PeriodontitisView official trial listing → -
Terminated NCT NCT02274740
Effect of Lixisenatide on Postprandial Lipid Profile in Obese Type 2 Diabetic Patients
Not yet reported Sanofi 2 participants Est. completion 2015-08 Added to GLP-1Other conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT02274948
Use of Metformin in Treatment of Childhood Obesity
Not yet reported University of Colombo 339 participants Est. completion 2016-04 1 siteOther conditions: Pediatric ObesityView official trial listing → -
Status unknown NCT NCT02275845
Medico-GDM Trial - Metformine to Prevent Gestational Diabetes Mellitus
Not yet reported Maasstad Hospital 400 participants Est. completion 2017-09 1 site Stand-aloneOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT02276274
Effect of Food on the Pharmacokinetics of Single Oral Dose Administration of a Fixed-Dose Combination of SYR-322 and Metformin Hydrochloride in Healthy Adult Male Subjects
Not yet reported Takeda 12 participants Est. completion 2014-06 1 siteOther conditions: Clinical PharmacologyView official trial listing → -
Completed NCT NCT02278965
Metformin and Omega-3 Fatty Acids in Woman With a History of Early Stage Breast Cancer
Not yet reported Katherine D. Crew 19 participants Est. completion 2017-04-19 1 site Stand-aloneOther conditions: Stage 0 Breast Carcinoma, Breast Neoplasms, Stage I Breast Carcinoma, Stage II Breast Carcinoma, Stage III Breast CarcinomaView official trial listing → -
Status unknown NCT NCT02279758
A Pilot Study of Metformin Treatment in Patients With Well-differentiated Neuroendocrine Tumors
Not yet reported Instituto do Cancer do Estado de São Paulo 30 participants 1 siteOther conditions: Well-differentiated Neuroendocrine TumorsView official trial listing → -
Completed NCT NCT02280057
Trial With Metformin in Women With Polycystic Ovary Syndrome
Not yet reported Herning Hospital 56 participants Est. completion 2002-12 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02280486
Efficacy and Safety of Saxagliptin VS. Glimepiride in Chinese T2DM Patients Controlled Inadequately With Metformin
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 388 participants Est. completion 2017-10 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT02282423
PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes
Not yet reported Mayo Clinic 26 participants Est. completion 2016-04 1 site Stand-aloneOther conditions: Diabetes, ObesityView official trial listing → -
Completed NCT NCT02283554
Platelet Rich Fibrin With 1% Metformin Gel for Treatment of Intrabony Defects
Not yet reported Government Dental College and Research Institute, Bangalore 120 participants Stand-aloneOther conditions: PeriodontitisView official trial listing → -
Completed NCT NCT02284893
Study to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin in Combination With Metformin Compared to Sitagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Therapy Alone
Not yet reported AstraZeneca 461 participants Est. completion 2016-09-20 79 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT02285855
Metformin in Non Small Cell Lung Cancer (NSCLC)
Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2019-01-05 1 site Stand-aloneOther conditions: Lung CancerView official trial listing → -
Completed NCT NCT02286128
Effect of NF-кB Dependent Proinflammation on Osteogenic Differentiation of the Mesenchymal Stem Cells in Type 2 Diabetes
Chiang Mai University 75 participants Est. completion 2018-05-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02288273
Study to Evaluate the Effect of BYDUREON on 24-hour Glucose Control in Metformin Treated Patients With Type 2 Diabetes.
Not yet reported AstraZeneca 239 participants Est. completion 2015-08 29 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02290184
PilAm Go4Health Weight Loss Program to Prevent Heart Disease
Not yet reported University of California, San Francisco 45 participants Est. completion 2017-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02291510
Assessing the PK of Met DR, Met IR, and Met XR in Healthy Subjects
Not yet reported Elcelyx Therapeutics, Inc. 20 participants Est. completion 2012-12 Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT02292290
Trial for People With Established Type 2 Diabetes During Ramadan
Not yet reported University of Leicester 99 participants Est. completion 2012-12 2 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT02294006
Activity and Safety of Everolimus+Octreotide LAR+Metformin in Advanced Pancreatic Well-differentiated NETs
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 26 participants Est. completion 2021-10 1 site Stand-aloneOther conditions: Well Differentiated Pancreatic Endocrine TumorView official trial listing → -
Completed NCT NCT02298192
A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration Algorithms
Not yet reported Novo Nordisk A/S 420 participants Est. completion 2015-12-23 84 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT02303405
Hydroxychloroquine Versus Pioglitazone in Combination Treatment for Type 2 Diabetes Mellitus
Not yet reported Charles Drew University of Medicine and Science 22 participants Est. completion 2017-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02304081
Saxagliptin in Combination With Dapagliflozin - Effects on Islet Cell Function
Not yet reported Prof. Dr. Thomas Forst 64 participants Est. completion 2016-08 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02304536
Comparison Between Laparoscopic Ovarian Diathermy and Urinary Purified FSH in Women With Clomiphene Citrate Resistant Polycystic Ovarian Syndrome.
Not yet reported Cairo University 210 participants 2 sitesOther conditions: InfertilityView official trial listing → -
Completed NCT NCT02305381
Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to Basal Insulin Alone or Basal Insulin in Combination With Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 397 participants Est. completion 2015-11-21 99 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Withdrawn NCT NCT02306070
Improving Fibrosis Outcomes With Metformin
Not yet reported Ottawa Hospital Research Institute Est. completion 2018-04-03 1 site Stand-aloneOther conditions: HIV Infection, Hepatitis CView official trial listing → -
Completed NCT NCT02308228
Metformin to Augment Strength Training Effective Response in Seniors (MASTERS)
Not yet reported Philip Kern 109 participants Est. completion 2018-06-28 2 sites Stand-aloneOther conditions: AgingView official trial listing → -
Status unknown NCT NCT02315287
Comparison of Lobeglitazone With Pioglitazone as Initial Triple Therapy for Diabetes Management
Not yet reported Seoul National University Bundang Hospital 190 participants Est. completion 2021-12-31 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT02319200
Primary Prevention Hepatocellular Carcinoma by Metformin
Not yet reported Assistance Publique - Hôpitaux de Paris 11 participants Est. completion 2016-04 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma, Hepatitis C, Chronic, CirrhosisView official trial listing → -
Status unknown NCT NCT02325245
Effects of Metformin in Pre-frail Elderly
Not yet reported Universitas Indonesia 150 participants Est. completion 2017-03 1 site Stand-aloneOther conditions: Pre-frail ElderlyView official trial listing → -
Completed NCT NCT02325401
Dose-finding Study of Metformin With Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma
Not yet reported University of Cincinnati 20 participants Est. completion 2020-02-21 1 site Stand-aloneOther conditions: Head and Neck CancerView official trial listing → -
Completed NCT NCT02325960
A Comparison of Exenatide and Insulin Glargine
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 44 participants Est. completion 2016-10 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT02336087
Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery
Not yet reported City of Hope Medical Center 21 participants Est. completion 2026-12-09 4 sites Stand-aloneOther conditions: Pancreatic Adenocarcinoma, Unresectable Pancreatic Carcinoma, Stage III Pancreatic Cancer AJCC v6 and v7, Stage IV Pancreatic Cancer AJCC v6 and v7View official trial listing → -
Completed NCT NCT02338193
Dapagliflozin and Metformin,Alone and in Combination, in Overweight/Obese Prior GDM Women
Not yet reported Woman's 69 participants Est. completion 2019-03-13 1 site Stand-aloneOther conditions: Diabetes Prevention in Women After GDM Who Are at High-riskView official trial listing → -
Completed NCT NCT02338921
Triple Combination Therapy in Type 2 Diabetic Patients Who Had Inadequate Glycemic Control With Combination Therapy
Not yet reported Seoul National University Bundang Hospital 78 participants Est. completion 2021-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02339168
Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer
Not yet reported University of California, Davis 25 participants Est. completion 2025-02-24 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT02341703
Ovulation Induction in Clomiphene Citrate Resistant PCO Women
Not yet reported Cairo University 100 participants Est. completion 2015-07 1 siteOther conditions: Polycystic Ovary Syndrome, InfertilityView official trial listing → -
Completed NCT NCT02342925
A Study of the Effect of RG1662 on Metformin in Healthy Volunteers
Not yet reported Hoffmann-La Roche 17 participants Est. completion 2015-05 1 site Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Completed NCT NCT02343926
Phase 3 Study to Compare the Efficacy and Safety of Gemigliptin and Vildagliptin as Add-on Therapy to Metformin in People With Type 2 Diabetes Inadequately Controlled With Metformin
Not yet reported Sanofi 443 participants Est. completion 2016-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02354027
The Drug-drug Interaction of SHR3824 and Metformin
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 12 participants Est. completion 2015-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02355145
Non-inteRvEntional Study to Observe rAtionaLe to Select add-on TherapY for Type 2 Diabetes Inadequately Controlled With Metformin.
AstraZeneca 1005 participants Est. completion 2016-07-28 3 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT02360618
Metformin and Simvastatin Use in Bladder Cancer
Not yet reported London Health Sciences Centre 44 participants Est. completion 2018-01 1 site Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Terminated NCT NCT02365233
Fatty Liver Study in Patients With Type II Diabetes
Not yet reported The University of Texas Medical Branch, Galveston 5 participants Est. completion 2016-12-31 1 siteOther conditions: Type II Diabetes, Nonalcoholic Fatty LiverView official trial listing → -
Status unknown NCT NCT02366377
The PK/PD, Efficacy, Safety and Tolerability Study of SHR3824 in Combination With Metformin in Type 2 Diabetes Mellitus Patients
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 168 participants Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02367066
A Phase I Study to Assess the Pharmacodynamics of Oral AR-C165395XX in Subjects With Type 2 Diabetes Mellitus (T2DM)
Not yet reported AstraZeneca 30 participants Est. completion 2015-05 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02368704
Role of Endoplasmic Reticulum Stress in the Pathophysiology of Type 2 Diabetes
Assistance Publique - Hôpitaux de Paris 40 participants Est. completion 2016-11 1 siteType 2 diabetes Other conditions: Endoplasmic Reticulum StressView official trial listing → -
Completed NCT NCT02372656
Simvastatin and Metformin in Chronic Periodontitis
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 98 participants Est. completion 2014-08Other conditions: Chronic PeriodontitisView official trial listing → -
Terminated NCT NCT02373865
Risk of Nocturnal Hypoglycemia and Arrhythmias With Sitagliptin Versus Glimepiride in Patients With Type 2 Diabetes
Not yet reported GWT-TUD GmbH 4 participants Est. completion 2017-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02375139
A Clinical Trial to Investigate Safety/Tolerability and Pharmacokinetics of DA-1229_01(Evogliptin/Metformin XR 2.5/500 mg x 2 Tablets) Compared to Co-administration of Evogliptin 5 mg and Metformin XR 1000 mg in Healthy Male Volunteers
Not yet reported Dong-A ST Co., Ltd. 36 participants Est. completion 2015-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02376166
Metformin for Rising PSA Remote Trial
Not yet reported Matthew Galsky 15 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT02378441
Phase 1 Study to Compare the Safety, Pharmacokinetic Profiles of CJ-30056 and Lipitor 20mg/Glucophage SR 750mg
Not yet reported HK inno.N Corporation 42 participants Est. completion 2015-08 Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02383563
Metformin for HIV Inflammation
Not yet reported University of Hawaii 12 participants Est. completion 2016-02 1 siteCardiovascular disease Other conditions: HIVView official trial listing → -
Completed NCT NCT02384109
A Pharmacist-Coordinated Implementation of the Diabetes Prevention Program
Not yet reported University of California, Los Angeles 521 participants Est. completion 2019-06 20 sites Stand-aloneOther conditions: Prediabetic StateView official trial listing → -
Terminated NCT NCT02393573
Attenuating The Post-Operative Insulin Resistance And Promoting Protein Anabolism
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 7 participants Est. completion 2018-03 1 sitePrediabetes Other conditions: Major Lung or Abdominal Surgery, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT02394158
Preventing Recurrent Gestational Diabetes With Metformin
Not yet reported Imperial College London 112 participants Est. completion 2019-09-30 2 sitesOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT02394652
The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized Trial
Not yet reported University Health Network, Toronto 16 participants Est. completion 2021-01-12 5 sites Stand-aloneOther conditions: Uterine Cervical Neoplasms, Squamous Cell Carcinoma, Adenocarcinoma, Carcinoma, AdenosquamousView official trial listing → -
Withdrawn NCT NCT02395237
COMPOUND (INN): HOE490O - GLIMEPIRIDE / METFORMIN HCl (Amaryl® M)0 (Glimepiride/Metformin Hydrochloride Immediate Release Combination Tablet) in Fed Conditions in Healthy Male and/or Female Subjects.
Not yet reported Pharmaceutical Research Unit, Jordan Est. completion 2015-12 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02401880
Effects of Linagliptin in Addition to Empagliflozin on Islet Cell Physiology
Not yet reported Profil Institut für Stoffwechselforschung GmbH 89 participants Est. completion 2015-12 2 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT02402348
Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis
Not yet reported West Virginia University 3 participants Est. completion 2016-08 1 site Stand-aloneOther conditions: Cancer of Head and NeckView official trial listing → -
Completed NCT NCT02405260
Add Glucokinase Activator to Target A1c
Not yet reported vTv Therapeutics 190 participants Est. completion 2016-09 20 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02407899
Protective Effects of Saxagliptin (And Vitamin D3) on β Cell Function in Adult-onset Latent Autoimmune Diabetes
Not yet reported Second Xiangya Hospital of Central South University 300 participants Est. completion 2020-12-31 39 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Terminated NCT NCT02409238
Insulin Resistance and Mild Cognitive Impairment (IRMCI) Study
Not yet reported SingHealth Polyclinics 105 participants Est. completion 2019-12-31 1 site Stand-aloneType 2 diabetes Other conditions: Mild Cognitive Impairment, Insulin ResistanceView official trial listing → -
Completed NCT NCT02411825
Multiple Ascending Dose Study in Healthy Male Subjects and Overweight to Obese Male and Female Type 2 Diabetes Mellitus (T2DM) Patients
Not yet reported Sanofi 76 participants Est. completion 2016-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02417090
Late Metabolic Effects of Metformin Therapy in Gestational Diabetes
Turku University Hospital 173 participants Est. completion 2019-12-01Other conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT02419612
A 52-week International, Multicenter Trial With a Long -Term Extension to Evaluate Saxagliptin With Dapagliflozin in Combination With Metformin Compared to Glimepiride in Combination With Metformin in Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Alone
Not yet reported AstraZeneca 444 participants Est. completion 2019-09-18 84 sitesOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02420262
A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 506 participants Est. completion 2016-10-05 117 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02420392
Effects of Dapagliflozin on the Incretin Sensitivity of the Pancreatic Beta Cell
Not yet reported Seoul National University Hospital 30 participants Est. completion 2016-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT02420652
Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy
Not yet reported Rutgers, The State University of New Jersey 27 participants Est. completion 2019-12-01 1 site Stand-aloneOther conditions: Recurrent Prostate Carcinoma, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer, Stage III Prostate CancerView official trial listing → -
Status unknown NCT NCT02426294
Comparison of Pioglitazone Versus Glimepiride in Type 2 Diabetes Inadequately Controlled With Metformin Plus Alogliptin
Not yet reported Pusan National University Hospital 154 participants Est. completion 2016-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02429258
Effect of Dapagliflozin on 24-hour Blood Glucose in T2DM Patients Inadequately Controlled With Either Metformin Or Insulin
Not yet reported AstraZeneca 226 participants Est. completion 2015-10 26 sites Stand-aloneOther conditions: Type II DiabetesView official trial listing → -
Completed NCT NCT02430870
TAK-648 Multiple-Rising Dose Study in Healthy Japanese Participants and Non-Japanese Participants With Type 2 Diabetes Mellitus
Not yet reported Takeda 48 participants Est. completion 2015-11 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02431676
Survivorship Promotion In Reducing IGF-1 Trial
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 121 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: Breast Cancer, Prostate Cancer, Lung Cancer, Colon Cancer, Melanoma of Skin, Endometrial Cancer, Liver Cancer, Pancreatic Cancer, Rectal Cancer, Kidney Cancer, Other Solid Malignant TumorsView official trial listing → -
Completed NCT NCT02432287
Metformin in Longevity Study (MILES).
Not yet reported Albert Einstein College of Medicine 16 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: AgingView official trial listing → -
Completed NCT NCT02434744
Study of KD026 in Combination With Metformin in Subjects With Type 2 Diabetes Mellitus
Not yet reported Response Pharmaceuticals 121 participants Est. completion 2016-03 10 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02435277
An Extension Protocol to Evaluate Dose Comparisons of Leucine-Metformin Combinations in Type 2 Diabetic Patients
Not yet reported NuSirt Biopharma 50 participants Est. completion 2016-01 9 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02437656
Combination of Metformin to Neoadjuvant Radiochemotherapy in the Treatment of Locally Advanced Rectal Cancer.
Not yet reported Centre Oscar Lambret 60 participants Est. completion 2017-03 11 sites Stand-aloneOther conditions: Rectal CancerView official trial listing → -
Status unknown NCT NCT02437812
Study of Paclitaxel, Carboplatin and Oral Metformin in the Treatment of Advanced Stage Ovarian Carcinoma
Not yet reported Gynecologic Oncology Associates 30 participants Est. completion 2021-04 1 site Stand-aloneOther conditions: Epithelial Ovarian CarcinomaView official trial listing → -
Status unknown NCT NCT02438020
Study of Efficacy of Metformin in the Treatment of Acanthosis Nigricans in Children With Obesity
Not yet reported Juan Pablo Castanedo-Cazares 30 participants Est. completion 2016-10 1 site Stand-aloneOther conditions: Acanthosis NigricansView official trial listing → -
Status unknown NCT NCT02438397
the Efficacy of Acarbose and Metformin on Blood Glucose Fluctuation When Combined With Premix Insulin
Not yet reported Shanghai 6th People's Hospital 80 participants Est. completion 2016-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02438540
Comparative the Effect of Metformin and Acupuncture on Weight Loss and Insulin Sensitivity
Not yet reported Amir Firouzjaei 43 participants Est. completion 2015-04 Stand-aloneOther conditions: Insulin Sensitivity, ObesityView official trial listing → -
Completed NCT NCT02440893
Understanding the Effect of Metformin on Corus CAD (or ASGES)
CardioDx 37 participants Est. completion 2014-06Cardiovascular disease Other conditions: Angina Pectoris, Chest Pain, Coronary Heart Disease, CAD, CVD, CHDView official trial listing → -
Status unknown NCT NCT02443922
Dynamic Responsiveness of Insulin Secretory Parameters To Sitagliptin and Glimeperide Administration in Type 2 DM
Not yet reported Foundation for the National Institutes of Health 100 participants Est. completion 2015-12 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02446834
Research of Intensive Lifestyle Intervention for PCOS Patients With IGT
Not yet reported RenJi Hospital 40 participants Est. completion 2018-04 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02449187
Investigate the Effect of Food on the Pharmacokinetics of JLP-1310 in Healthy Male Volunteers
Not yet reported Jeil Pharmaceutical Co., Ltd. 16 participants Est. completion 2018-03-09 1 siteOther conditions: Diabetes, HyperlipidemiaView official trial listing → -
Completed NCT NCT02452632
A Study to Assess the Efficacy and Safety of ASP1941 in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin and Sitagliptin
Not yet reported Astellas Pharma Korea, Inc. 143 participants Est. completion 2017-01-05 22 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02453685
A Study to Compare Insulin Intensification of Biphasic Insulin Aspart 30 and Insulin Analogues (Insulin Glargine and Insulin Aspart) in Insulin naïve Type 2 Diabetic Patients
Not yet reported Novo Nordisk A/S 335 participants Est. completion 2016-09-20 41 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02456428
Incretin-based Drugs and the Risk of Heart Failure
Canadian Network for Observational Drug Effect Studies, CNODES 1499650 participants Est. completion 2015-05 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02457286
Improving Insulin Resistance To Treat Non-Alcoholic Fatty Liver Disease: A Pilot Study
Not yet reported Northwell Health Est. completion 2017-07 1 site Stand-aloneMASLDView official trial listing → -
Terminated NCT NCT02460354
Metformin and Congenital Nephrogenic Diabetes Insipidus
Not yet reported Emory University 2 participants Est. completion 2017-06 3 sites Stand-aloneOther conditions: Diabetes InsipidusView official trial listing → -
Completed NCT NCT02461667
Alendronate Compared to Metformin in Chronic Periodontitis
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 108 participants Est. completion 2015-03Other conditions: Chronic PeriodontitisView official trial listing → -
Status unknown NCT NCT02462369
Saxagliptin's Effects on Microalbuminuria Improvement in Type 2 Diabetic Patients
Not yet reported The Second Hospital of Nanjing Medical University 88 participants Est. completion 2017-10Other conditions: Microalbuminuria, Microalbuminuria /Creatinine Ratios ACRView official trial listing → -
Completed NCT NCT02463357
Three New Ideas to Protect Special Forces From the Stress of High Altitude
Not yet reported University of Colorado, Denver 148 participants Est. completion 2016-09 1 site Stand-aloneOther conditions: Mountain SicknessView official trial listing → -
Completed NCT NCT02470039
Trial to Compare NNC0123-0000-0338 in a Tablet Formulation and Insulin Glargine in Subjects With Type 2 Diabetes Currently Treated With Oral Antidiabetic Therapy
Not yet reported Novo Nordisk A/S 50 participants Est. completion 2015-12-31 2 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT02470546
Metformin Experience on Minimal Hepatic Encephalopathy
Not yet reported Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 30 participants Est. completion 2016-12 1 siteOther conditions: Liver Cirrhosis, Hepatic EncephalopathyView official trial listing → -
Completed NCT NCT02471404
Efficacy and Safety of Dapagliflozin and Dapagliflozin Plus Saxagliptin in Combination With Metformin in Type 2 Diabetes Patients Compared With Sulphonylurea
Not yet reported AstraZeneca 939 participants Est. completion 2017-03-13 173 sitesType 2 diabetes Other conditions: Inadequate Glycaemic ControlView official trial listing → -
Terminated NCT NCT02472353
Use of Metformin to Reduce Cardiac Toxicity in Breast Cancer
Not yet reported Avera McKennan Hospital & University Health Center 30 participants Est. completion 2018-05-23 1 site Stand-aloneOther conditions: Breast Cancer, Breast TumorsView official trial listing → -
Terminated NCT NCT02473094
Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer
Not yet reported University of Campinas, Brazil 3 participants Est. completion 2016-02 1 site Stand-aloneOther conditions: Rectal Neoplasms, Adenocarcinoma, CarcinomaView official trial listing → -
Completed NCT NCT02475070
Vildagliptin Versus Dapagliflozin on Glucagon
Not yet reported Lund University 28 participants Est. completion 2017-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02475499
Incretin-based Drugs and Pancreatic Cancer
Canadian Network for Observational Drug Effect Studies, CNODES 886172 participants Est. completion 2015-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02476760
Incretin-based Drugs and Acute Pancreatitis
Canadian Network for Observational Drug Effect Studies, CNODES 1417914 participants Est. completion 2015-04 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02477969
Efficacy and Safety Study of PEX168 in Combination Therapy Diabetes Mellitus Type 2 Patients With Metformin
Not yet reported Jiangsu Hansoh Pharmaceutical Co., Ltd. 587 participants Est. completion 2017-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02480465
Efficacy and Safety of Lobeglitazone Versus Sitagliptin
Not yet reported Chong Kun Dang Pharmaceutical 248 participants Est. completion 2017-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02483299
Liraglutide as Add on Therapy on Metformin in Women With Polycystic Ovary Syndrome
Not yet reported University Medical Centre Ljubljana 40 participants Est. completion 2015-04 1 siteOther conditions: PCOS, ObesityView official trial listing → -
Withdrawn NCT NCT02484209
DiaFrail: A Short Duration Study in Older People ( DIAFRAIL Study)
Not yet reported Diabetes Frail Ltd Est. completion 2016-11 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02488564
A Study of Liposomal Doxorubicin+Docetaxel+Trastuzumab+Metformin in Operable and Locally Advanced HER2 Positive Breast Cancer
Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 49 participants Est. completion 2020-03-17 9 sites Stand-aloneOther conditions: HER-2 Positive Breast CancerView official trial listing → -
Completed NCT NCT02491333
The RCT of Acupuncture on PCOS Combined With IR
Not yet reported The First Affiliated Hospital of Guangzhou Medical University 342 participants Est. completion 2018-10 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Insulin ResistanceView official trial listing → -
Terminated NCT NCT02495103
Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 7 participants Est. completion 2020-02-06 1 site Stand-aloneOther conditions: Renal Cell Carcinoma, Hereditary Leiomyomatosis, Renal Cell CancerView official trial listing → -
Completed NCT NCT02496000
Phase II Safety and Efficacy Study of Oral ORMD-0801 in Patients With Type 2 Diabetes Mellitus
Not yet reported Oramed, Ltd. 188 participants Est. completion 2016-09-13 34 sitesOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT02496741
Metformin And Chloroquine in IDH1/2-mutated Solid Tumors
Not yet reported, Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 15 participants Est. completion 2019-11-18 3 sites Stand-aloneObstructive sleep apnea Other conditions: Glioma, CholangiocarcinomaView official trial listing → -
Completed NCT NCT02497313
Effect of Metformin and Cholecystokinin-mediated Gallbladder Emptying on GLP-1 Secretion in Type 2 Diabetes
Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2016-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02498522
Effect of Metformin on Early Pregnancy Loss in Pregnant Women With Polycystic Ovarian Syndrome
Not yet reported Ain Shams University 166 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Terminated NCT NCT02500147
Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)
Not yet reported Columbia University 3 participants Est. completion 2021-03-03 1 site Stand-aloneMetabolic syndrome Other conditions: Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT02500628
Heart Rate Variability in Response to Metformin Challenge
Not yet reported Woodinville Psychiatric Associates 61 participants Est. completion 2016-02 1 site Stand-aloneType 2 diabetes Other conditions: Fibromyalgia, Mitochondrial Diseases, Movement DisordersView official trial listing → -
Status unknown NCT NCT02501616
Effect of Dapagliflozine on Systemic and Renal Endothelial Function
Not yet reported Seoul National University Hospital 22 participants 1 siteType 2 diabetes Other conditions: Endothelial FunctionView official trial listing → -
Status unknown NCT NCT02501850
The Effect of the GLP-1 Receptor Agonists on Blood Levels of Lipoprotein (a)
Not yet reported Hospital Universitari Vall d'Hebron Research Institute 40 participants Est. completion 2015-10 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02502344
Effect of Medical Interventions in Insulin Resistance on Prevalence of Abnormal Glucose Tolerance
Not yet reported Beijing Tsinghua Chang Gung Hospital 60 participants 1 site Stand-aloneOther conditions: Insulin ResistanceView official trial listing → -
Status unknown NCT NCT02503943
Effects of Incretin on the Blood Pressure and Lipid in Patients With Overweight or Obese Diabetes
Not yet reported Third Affiliated Hospital of Third Military Medical University 90 participants Est. completion 2016-09Type 2 diabetes Other conditions: Overweight, Obesity, Masked HypertensionView official trial listing → -
Completed NCT NCT02505516
BLADDER CANCER SCREENING AMONG DIABETIC PATIENTS
Not yet reported UFUOMA MILLER FAKPOR 150 participants Est. completion 2014-02 1 siteOther conditions: Bladder Cancer, DiabetesView official trial listing → -
Status unknown NCT NCT02506777
Neoadjuvant FDC With Melatonin or Metformin for Locally Advanced Breast Cancer.
Not yet reported N.N. Petrov National Medical Research Center of Oncology 96 participants Est. completion 2020-08 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT02506790
Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer
Not yet reported N.N. Petrov National Medical Research Center of Oncology 96 participants Est. completion 2022-08 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT02511665
Metformin And Longevity
Not yet reported Guy's and St Thomas' NHS Foundation Trust 185 participants Est. completion 2017-07 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT02512523
Exploratory Study to Compare the Effects of Tenelia® or Januvia® on Glucose Variability in add-on to Metformin (CGMS Study)
Not yet reported Handok Inc. 39 participants Est. completion 2016-09-26 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02514629
Testosterone, Metformin, or Both, for Hypogonadism in Obese Males
Not yet reported Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud 107 participants Est. completion 2016-07-12 1 site Stand-aloneOther conditions: Hypogonadism, ObesityView official trial listing → -
Completed NCT NCT02515773
Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs
Not yet reported Melissa Delbello 1565 participants Est. completion 2023-06 29 sites Stand-aloneOther conditions: Bipolar DisorderView official trial listing → -
Completed NCT NCT02516085
Improved Muscle Function in Duchenne Muscular Dystrophy Through L-Arginine and Metformin
Not yet reported University Hospital, Basel, Switzerland 5 participants Est. completion 2012-10 Stand-aloneOther conditions: Duchenne Muscular DystrophyView official trial listing → -
Terminated NCT NCT02521753
Omega 3 Polyunsaturated Fatty Acids (PUFA) or Magnesium in Obese Polycystic Ovary Syndrome Patients
Not yet reported Coordinación de Investigación en Salud, Mexico 123 participants Est. completion 2025-03 1 siteOther conditions: Polycystic Ovary Syndrome, ObesityView official trial listing → -
Terminated NCT NCT02523898
Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant
Not yet reported Semnan University of Medical Sciences 388 participants Est. completion 2022-04 Stand-aloneOther conditions: Polycystic Ovary Syndrome, HyperandrogenismView official trial listing → -
Completed NCT NCT02524821
The Effect of Gelesis100 on the Pharmacokinetics of Metformin
Not yet reported Gelesis, Inc. 24 participants Est. completion 2015-12 1 siteOther conditions: Healthy Overweight ObeseView official trial listing → -
Completed NCT NCT02526524
Dose-Ranging Study to Evaluate the Glycemic Effects, Safety, and Tolerability of Metformin Delayed Release in Subjects With T2DM
Not yet reported Elcelyx Therapeutics, Inc. 571 participants Est. completion 2016-09 137 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02526615
Effects of Rosiglitazone and Metformin on Metabolism in Type 2 Diabetes
Not yet reported Turku University Hospital 48 participants Est. completion 2001-12 3 sitesType 2 diabetes Other conditions: Insulin SensitivityView official trial listing → -
Status unknown NCT NCT02526810
Comparison of Glycaemic Fluctuation and Oxidative Stress Between Two Short-term Therapies for Type 2 Diabetes
Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 70 participants Est. completion 2016-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT02531308
Metformin in Combination With Standard Induction Therapy for Large B-cell Lymphoma (DLBCL)
Not yet reported Rush University Medical Center 5 participants Est. completion 2016-07 1 site Stand-aloneOther conditions: Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT02532855
A Study to Assess the Addition of Sitagliptin to Metformin Compared With the Addition of Dapagliflozin to Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) and Mild Renal Impairment Who Have Inadequate Glycemic Control on Metformin With or Without a Sulfonylurea (MK-0431-838)
Not yet reported Merck Sharp & Dohme LLC 614 participants Est. completion 2017-10-10 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02535299
Par-4 and Telomere-telomerase System in Type 2 Diabetes Patients Who Received GLP-1 or Metformin Treatment
Not yet reported Third Military Medical University 200 participants Est. completion 2019-12 1 site Added to GLP-1Other conditions: GLP-1;Metformin;Telomere-telomerase System;Par-4View official trial listing → -
Status unknown NCT NCT02535975
The Effects of Metformin in Patients With Mild Graves' Ophthalmopathy
Not yet reported Yonsei University 80 participants Est. completion 2019-10 1 siteOther conditions: Mild Graves' OphthalmopathyView official trial listing → -
Completed NCT NCT02546050
The Effect of Metformin on Composition of Human Gut Bacteria
Not yet reported Oluf Borbye Pedersen 26 participants Est. completion 2016-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02546609
The Effect Of NS-0200 Versus Placebo On Hepatic Fat Content In Patients With Non Alcoholic Fatty Liver Disease
Not yet reported NuSirt Biopharma 91 participants Est. completion 2017-01-31 13 sites Stand-aloneMASLDView official trial listing → -
Status unknown NCT NCT02548741
Evaluation of the Metformin Effect on Methylglyoxal in Patients With Type 2 Diabetes
Not yet reported University of Arizona 120 participants Est. completion 2017-08Type 2 diabetesView official trial listing → -
Terminated NCT NCT02549924
Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus
Not yet reported University of Guadalajara 22 participants Est. completion 2018-02-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02551874
A 24-week Open-Label, Phase 3b Trial With a 28-week Extension to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin Compared to Insulin Glargine in Subjects withType 2 Diabetes Who Have Glycemic Control on Metformin
Not yet reported AstraZeneca 650 participants Est. completion 2017-11-10 40 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02552355
Milk Protein Feeding After Aerobic Exercise in Older Adults With Pre-diabetes Taking the Biguanide Metformin
Not yet reported Colorado State University 56 participants Est. completion 2017-08 1 site Stand-aloneOther conditions: Physical ActivityView official trial listing → -
Completed NCT NCT02554877
A 12-week Study To Evaluate PF-06291874 Once a Day in Adults With T2DM Inadequately Controlled On Metformin
Not yet reported Pfizer 206 participants Est. completion 2016-08 38 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02561130
Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Forxiga
Not yet reported Population Health Research Institute 154 participants Est. completion 2018-12-31 7 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02564926
Foxiga Korea Local Phase 4 Study
Not yet reported AstraZeneca 125 participants Est. completion 2018-01-15 14 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02565368
A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.5/1000 mg in Healthy Male Volunteers
Not yet reported Chong Kun Dang Pharmaceutical 26 participants Est. completion 2015-08 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT02565862
A Drug-drug Interaction Study Between Daclatasvir and Metformin
Not yet reported Radboud University Medical Center 20 participants Est. completion 2016-04 1 site Stand-aloneOther conditions: Hepatitis C, Diabetes Mellitus, Insulin ResistanceView official trial listing → -
Completed NCT NCT02567994
Tenelia Triple Combination Study
Not yet reported Handok Inc. 201 participants Est. completion 2017-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02570672
Metformin for Preventing Frailty in High-risk Older Adults
Not yet reported The University of Texas Health Science Center at San Antonio 141 participants Est. completion 2024-02-07 1 site Stand-aloneOther conditions: FrailtyView official trial listing → -
Withdrawn NCT NCT02571608
Continuation of Metformin to Improve And Keep Peri-operative Glycemic Control
Not yet reported McMaster University Est. completion 2022-12-31Type 2 diabetesView official trial listing → -
Completed NCT NCT02574845
DDI (Effect of Metformin and Furosemide on Rosuvastatin PK)
Not yet reported Boehringer Ingelheim 18 participants Est. completion 2015-12-14 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02580331
1% Metformin Gel in the Treatment of Class II Furcation Defects
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 64 participants Est. completion 2015-09 1 siteOther conditions: Chronic PeriodontitisView official trial listing → -
Active, not recruiting NCT NCT02581137
Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion
Not yet reported National Cancer Institute (NCI) 26 participants Est. completion 2026-12-19 4 sites Stand-aloneOther conditions: Erythroplakia, Hyperplasia, Oral Cavity Carcinoma, Oral LeukoplakiaView official trial listing → -
Completed NCT NCT02582242
Comparing Efficacy and Safety of Thrice Daily Versus Twice Daily NovoMix® 30 (Biphasic Insulin Aspart 30) in Subjects With Type 2 Diabetes Inadequately Controlled With Basal Insulin
Not yet reported Novo Nordisk A/S 437 participants Est. completion 2017-04-18 50 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02583919
Safety, Tolerability and Efficacy of ISIS-GCGRRx in Patients With Type 2 Diabetes
Not yet reported Ionis Pharmaceuticals, Inc. 79 participants Est. completion 2017-05-11 19 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT02584075
Evaluate the Effect of Exenatide Treatment on Coronary Artery Endothelial Function
Not yet reported Beijing Chao Yang Hospital 100 participants Est. completion 2018-01 Added to GLP-1Other conditions: Coronary Endothelial FunctionView official trial listing → -
Completed NCT NCT02586129
Clinical Trial of YH14755 in Subjects With Dyslipidemia and Type II Diabetes
Not yet reported Yuhan Corporation 249 participants Est. completion 2017-07-07 1 siteOther conditions: Dyslipidemia, Type II DiabetesView official trial listing → -
Completed NCT NCT02586636
Impact of OCT1 on Metformin Tolerance
Not yet reported NHS Tayside 61 participants Est. completion 2018-04-09 1 siteOther conditions: ToleranceView official trial listing → -
Status unknown NCT NCT02587741
Comparison of Diabetes Retinopathy Among Type 2 Diabetic Patients Treated With Different Regimens
Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 600 participants Est. completion 2025-07 1 site Stand-aloneOther conditions: Diabetic RetinopathyView official trial listing → -
Completed NCT NCT02588859
Study to Understand Usage and Effect of Saxagliptin as First Add-On After Metformin in Indian Type 2 Diabetes Mellitus Patients
AstraZeneca 1200 participants Est. completion 2016-12-26 31 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02593097
Metformin for the Prevention of Episodic Migraine (MPEM)
Not yet reported Mayo Clinic 34 participants Est. completion 2019-06 1 site Stand-aloneOther conditions: MigraineView official trial listing → -
Completed NCT NCT02597049
A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 424 participants Est. completion 2017-02 41 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02597101
Anti-Inflammatory Small Drug Adjunctive Therapy for Type 2 Diabetes
Not yet reported Nick Giannoukakis, PhD 14 participants Est. completion 2019-06-15 1 site Stand-aloneType 2 diabetes Other conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT02597400
Drug-Drug Interaction Study of Glucokinase Activator HMS5552 and Metformin in T2DM
Not yet reported Hua Medicine Limited 12 participants Est. completion 2015-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02607410
Sitagliptin (DPP-4 Inhibitor) and NPH Insulin in Patients With T2D
Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2014-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02609815
Initial Combination of Gemigliptin and Metformin on Microbiota Change
Not yet reported Seoul National University Bundang Hospital 70 participants Est. completion 2021-03-15 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02611518
A Pharmacokinetic Interaction Study Between JNJ-54861911 and Transporter Substrates Rosuvastatin and Metformin in Healthy Participants
Not yet reported Janssen Research & Development, LLC 32 participants Est. completion 2016-06-14 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02613897
ESR-15-11293 - Saxa/Dapa, Safety and Efficacy Study
Not yet reported The University of Texas Health Science Center at San Antonio 56 participants Est. completion 2018-06-30 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02614339
Effect of Adjunctive Metformin on Recurrence of Non-DM Colorectal Cancer Stage II High-risk/ III Colorectal Cancer
Not yet reported Yonsei University 593 participants Est. completion 2021-07 1 site Stand-aloneOther conditions: Non-DM Stage II High-risk Colorectal Cancer, Non-DM Stage III Colorectal CancerView official trial listing → -
Completed NCT NCT02614859
Bicalutamide With or Without Metformin for Biochemical Recurrence in Overweight or Obese Prostate Cancer Patients
Not yet reported Fox Chase Cancer Center 29 participants Est. completion 2020-01-24 2 sites Stand-aloneOther conditions: Cancer of ProstateView official trial listing → -
Completed NCT NCT02616666
A Pragmatic Randomized Trial to Evaluate the Comparative Effectiveness Between Dapagliflozin and Standard of Care in Type 2 Diabetes Patients
Not yet reported University of Liverpool 632 participants Est. completion 2025-12-12 132 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02621489
Effects on Re-endothelialisation With Bydureon Treatment in Type 2 Diabetes Subjects
Not yet reported Karolinska Institutet 38 participants Est. completion 2022-10 1 site Added to GLP-1Other conditions: Atherosclerosis, Diabetes, RestenosisView official trial listing → -
Completed NCT NCT02623998
Remission Evaluation of a Metabolic Intervention in Type 2 Diabetes With Sitagliptin (REMIT-Sita)
Not yet reported Population Health Research Institute 102 participants Est. completion 2019-11-30 6 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02627027
A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.25/750 mg in Healthy Male Volunteers
Not yet reported Chong Kun Dang Pharmaceutical 26 participants Est. completion 2015-09 1 siteOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT02627898
Effect of Green Tea Extract on Arterial Stiffness in Type 2 Diabetes Mellitus
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2016-12 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02629627
Conjugated Linoleic Acid / Leucine Versus Metformin on Visceral Fat in Metabolic Syndrome
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 104 participants Est. completion 2017-10 Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT02630706
A Study to Evaluate the Efficacy and Safety of Ertugliflozin in Asian Participants With Type 2 Diabetes and Inadequate Glycemic Control on Metformin Monotherapy (MK-8835-012)
Not yet reported Merck Sharp & Dohme LLC 506 participants Est. completion 2017-12-27 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02633488
Effect of Metformin on Insulin Sensitivity and Pan-Arterial Vascular Function in Adults With Metabolic Syndrome
Not yet reported University of Virginia 19 participants Est. completion 2016-07 1 site Stand-aloneMetabolic syndrome Other conditions: Insulin SensitivityView official trial listing → -
Completed NCT NCT02635386
EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)
Not yet reported Woman's 119 participants Est. completion 2020-10-09 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, ObesityView official trial listing → -
Completed NCT NCT02635646
Interdisciplinary and Family Intervention to Prevent Type 2 Diabetes
Not yet reported Universidad de Guanajuato 122 participants Est. completion 2017-02 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT02637037
A Study to Assess the Bioequivalence of Dapagliflozin/Metformin XR Fixed-dose Combination Tablets in Healthy Subjects
Not yet reported AstraZeneca 80 participants Est. completion 2016-04-07 1 site Stand-aloneOther conditions: Bioequivalence, Fixed Dose Combination Tablets, Healthy Male and Female SubjectsView official trial listing → -
Completed NCT NCT02638805
Study of the Safety and Tolerability of Switching to ITCA 650 in Patients With Type 2 Diabetes Receiving Liraglutide
Not yet reported Intarcia Therapeutics 136 participants Est. completion 2017-10 36 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Terminated NCT NCT02640534
Investigation of Metformin in Patients With Castration Resistant Prostate Cancer in Combination With Enzalutamide vs. Enzalutamide Alone
Not yet reported Swiss Cancer Institute 169 participants Est. completion 2023-03-16 16 sites Stand-aloneOther conditions: Cancer of the Prostate, Prostate CancerView official trial listing → -
Completed NCT NCT02644577
Metformin for Treatment Antipsychotic-induced Metabolic Syndrome in Bipolar Disorder Patients
Not yet reported China Medical University, China 110 participants Est. completion 2015-09 1 site Stand-aloneOther conditions: Bipolar DisorderView official trial listing → -
Status unknown NCT NCT02644954
Assessing the Efficacy and Safety of Metformin in Treatment of Moderate Psoriasis
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 40 participantsOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT02647320
12-Week Study of DS-8500a in Subjects With Type 2 Diabetes Mellitus on Metformin
Not yet reported Daiichi Sankyo 298 participants Est. completion 2017-01-31 58 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02648854
Investigate the Effect of Food on the Pharmacokinetic Characteristics of CKD-395 in Healthy Male Volunteers
Not yet reported Chong Kun Dang Pharmaceutical 26 participants Est. completion 2015-11 1 siteOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT02653209
TriMaster: Study of a DPP4 Inhibitor, SGLT2 Inhibitor and Thiazolidinedione as Third Line Therapy in Patients With Type 2 Diabetes.
Not yet reported Royal Devon and Exeter NHS Foundation Trust 525 participants Est. completion 2021-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02653599
A Study to Evaluate Safety and Efficacy of TTP273 for 12 Weeks in Subjects With Type 2 Diabetes
Not yet reported vTv Therapeutics 174 participants Est. completion 2017-01 30 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02656017
Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease
Not yet reported Kyongtae Ty Bae, M.D., Ph.D. 97 participants Est. completion 2020-12-07 2 sites Stand-aloneOther conditions: Polycystic Kidney, Autosomal DominantView official trial listing → -
Completed NCT NCT02659306
Metformin Immunotherapy in HIV Infection
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 22 participants Est. completion 2020-02 1 site Stand-aloneOther conditions: HIV InfectionView official trial listing → -
Status unknown NCT NCT02670018
BE Study of the Combinations of Gemigliptin 50mg and Metformin HCl Extended Release 2000mg in Comparison to Each Component Administered Alone
Not yet reported LG Life Sciences 25 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02672488
Metformin Plus Sorafenib for Advanced HCC
Not yet reported Tianjin Medical University Cancer Institute and Hospital 82 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT02681094
A Multi-Center, Randomized, Double-Blind, Phase III Trial to Evaluate the Safety and Efficacy of Saxagliptin Co-administered With Dapagliflozin Compared to Saxagliptin or Dapagliflozin All Given as add-on Therapy to Metformin in Subject With Type 2 Diabetes
Not yet reported AstraZeneca 905 participants Est. completion 2017-07-15 110 sitesType 2 diabetes Other conditions: Inadequate Glycaemic ControlView official trial listing → -
Completed NCT NCT02682121
Mitochondrial-related Platelet Transcript Expression Levels in Pre-diabetic Subjects Randomized to Metformin or Placebo
Not yet reported University of Utah 55 participants Est. completion 2017-01 1 sitePrediabetesView official trial listing → -
Completed NCT NCT02682563
Renoprotective Effects of Dapagliflozin in Type 2 Diabetes
Not yet reported M.H.H. Kramer 44 participants Est. completion 2018-09 1 siteType 2 diabetes Other conditions: Diabetic NephropathiesView official trial listing → -
Completed NCT NCT02683226
Comparison of Alogliptin Versus Alogliptin and Pioglitazone on Insulin Resistance of Metformin Treated Women With PCOS
Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2015-07 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Insulin ResistanceView official trial listing → -
Completed NCT NCT02684578
Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMD
Not yet reported University of California, San Francisco 66 participants Est. completion 2022-10 12 sites Stand-aloneOther conditions: Age-Related Macular Degeneration, Macular Degeneration, Age-Related, Dry Macular Degeneration, Geographic AtrophyView official trial listing → -
Completed NCT NCT02685774
A Clinical Study to Compare the Pharmacokinetic Characteristics of CKD-395 0.25/500mg in Healthy Male Volunteers
Not yet reported Chong Kun Dang Pharmaceutical 26 participants Est. completion 2016-04 1 siteOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT02686177
Effect of GLP-1 on Angiogenesis
Not yet reported Assistance Publique - Hôpitaux de Paris 50 participants Est. completion 2021-05-28 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02686476
Effect of Empagliflozin on Liver Fat Content in Patients With Type 2 Diabetes
Not yet reported Medanta, The Medicity, India 100 participants Est. completion 2017-12 1 siteOther conditions: Non Alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT02689843
Effects of Cyproterone Compound-spironolactone, Metformin and Pioglitazone on Inflammatory Markers in PCOS
Not yet reported Shiraz University of Medical Sciences 90 participants Est. completion 2018-12-30 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02693392
Clinical Evaluation of Fenugreek Seed Extract, a Nutraceutical in Patients With Type- 2 Diabetes
Not yet reported All India Institute of Medical Sciences, Bhubaneswar 200 participants Est. completion 2018-08-16 1 site Stand-aloneOther conditions: Type-2 Diabetes MellitusView official trial listing → -
Completed NCT NCT02694263
Canagliflozin (Invokana™) vs. Standard Dual Therapy Regimen for T2DM During Ramadan
Not yet reported University of Leicester 25 participants Est. completion 2018-09-13 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02694289
Effects of Metformin in Heart Failure Patients
Not yet reported Maya Guglin Est. completion 2018-09-10Type 2 diabetesView official trial listing → -
Completed NCT NCT02695121
Cancer in Patients on Dapagliflozin and Other Antidiabetic Treatment
AstraZeneca 2133575 participants Est. completion 2025-01-30 4 sitesOther conditions: Breast Cancer, Bladder CancerView official trial listing → -
Completed NCT NCT02695810
The PRE-D Trial: Effect of Dapagliflozin, Metformin and Physical Activity in Pre-diabetes
Not yet reported Steno Diabetes Center Copenhagen 120 participants Est. completion 2019-01-13 1 siteOther conditions: Prediabetic State, ObesityView official trial listing → -
Completed NCT NCT02696941
SGLT2 Inhibitors and Metformin on Metabolism and Non-Alcoholic SteatoHepatitis
Not yet reported University of Oxford 20 participants Est. completion 2018-04-01 1 site Stand-aloneOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Status unknown NCT NCT02708758
Efficacy of Treatment for Gestational Diabetes Diagnosed by the IADPSG Criteria.
Not yet reported Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes 400 participants Est. completion 2021-12 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT02710448
May Metformin be Used in Renal Failure?
Not yet reported Centre Hospitalier Universitaire, Amiens 82 participants Est. completion 2015-10 1 site Stand-aloneOther conditions: Renal Disorder Associated With Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT02712619
Pharmacokinetic-Pharmacodynamic Relationship of Metformin in Healthy Volunteers
Not yet reported Seoul National University Hospital 20 participants Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT02719132
Effect of DapagliFLOzin on Quality of Life in Patients With Type 2 Diabetes in a Real Clinical PrActice
Not yet reported AstraZeneca Est. completion 2017-11 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02719756
Effect of SGLT-2 Inhibitor Dapagliflozin on Glycemic Variability in Patients With Diabetes Mellitus Type 2
Not yet reported Research Clinical Centre of the Russian Railways, JSC 100 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Diabetes Mellitus, Hypoglycemic EpisodesView official trial listing → -
Completed NCT NCT02722239
An Open-label, Randomized, Crossover Study of Comparative Pharmacokinetics and Bioequivalence of Dapagliflozin + Metformin, 10 mg + 1000 mg Versus the Combined Use of Forxiga™, 10 mg and Two Glucophage® Long, ER Tablets, 500 mg Co-administered to Healthy Volunteers Under Standard Fed Conditions
Not yet reported AstraZeneca 40 participants Est. completion 2016-05-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT02726490
Glyburide vs Glucovance in the Treatment of GDM
Not yet reported Texas Tech University Health Sciences Center, El Paso 7 participants Est. completion 2018-08-14 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT02730377
Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1991 participants Est. completion 2019-08-12 232 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT02730741
Study of the Efficacy and Tolerance of Oral Treatment With a Total Freeze-dried Culture of Lcr Restituo® Sachets (Lactobacillus Rhamnosus Lcr35®) on Intolerance to Metformin (Diarrhoea) in Patients With Diabetes Type 2
Not yet reported Biose 60 participants 1 siteOther conditions: AntidiarrhoeaView official trial listing → -
Completed NCT NCT02733679
Response of Individuals With Ataxia-Telangiectasia to Metformin and Pioglitazone
Not yet reported NHS Tayside 27 participants Est. completion 2017-08-30 1 site Stand-aloneOther conditions: Ataxia-TelangiectasiaView official trial listing → -
Completed NCT NCT02737657
An Observational Study to Evaluate Tolerability of Canagliflozin and Sulphonylurea in Type 2 Diabetes Patients During Ramadan
Janssen-Cilag International NV 379 participants Est. completion 2016-09 9 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02738879
Randomized Sitagliptin Withdrawal Study (MK-0431-845)
Not yet reported Merck Sharp & Dohme LLC 746 participants Est. completion 2018-01-30 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02741960
The Effect of Metformin on Reducing Lupus Flares
Not yet reported RenJi Hospital 180 participants Est. completion 2018-12-07 1 site Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Completed NCT NCT02743260
Drug Transporter Interaction Study PHENTRA_2015_KPUK
Not yet reported University of Cologne 24 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02744131
OCP vs Metformin for Improvement in Clinical Symptoms and Metabolic Markers in Indian PCOS Women
Not yet reported Kar Clinic & Hospital Pvt. Ltd. 100 participants Est. completion 2019-12 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02744976
Coronary Artery Disease Progression in Patients With Prediabetes
Not yet reported Pauls Stradins Clinical University Hospital 70 participants Est. completion 2021-09 1 site Stand-aloneCardiovascular disease Other conditions: Atherosclerosis, Prediabetic StateView official trial listing → -
Status unknown NCT NCT02745886
Metformin Induces a Dietary Restriction-like State in Human
Not yet reported Xiang Guang-da 60 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Overweight Subjects, Metformin, AgingView official trial listing → -
Completed NCT NCT02745912
Study to Evaluate the Effect of Naltrexone and Bupropion Combination on the Pharmacokinetics of Metformin in Healthy Participants
Not yet reported Orexigen Therapeutics, Inc 30 participants Est. completion 2016-08 Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT02749032
Feed-Back Suppression of Meal-Induced Glucagon-like Peptide 1 (GLP-1) Secretion
Not yet reported Michael A. Nauck 24 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02751307
Adjunctive Low-dose Metformin in Patients With Schizophrenia and Metabolic Abnormalities
Not yet reported Taipei Medical University WanFang Hospital 55 participants Est. completion 2015-01Metabolic syndromeView official trial listing → -
Completed NCT NCT02752113
Effects of Empagliflozin + Linagliptin vs Metformin + Insulin Glargine on Renal and Vascular Changes in Type 2 Diabetes
Not yet reported Institut für Pharmakologie und Präventive Medizin 101 participants Est. completion 2019-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02752412
Efficacy and Safety of LixiLan Versus Insulin Glargine Alone Both With Metformin in Japanese With Type 2 Diabetes Mellitus Inadequately Controlled on Basal Insulin and Oral Antidiabetic Drugs
Not yet reported Sanofi 513 participants Est. completion 2018-10-04 122 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02755844
Safety and Efficacy of Metronomic Cyclophosphamide, Metformin and Olaparib in Endometrial Cancer Patients
Not yet reported, Not yet reported Hospices Civils de Lyon 35 participants Est. completion 2020-06 6 sites Stand-aloneOther conditions: Recurrent Endometrial CancerView official trial listing → -
Completed NCT NCT02760342
A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Metformin
Not yet reported Astellas Pharma Inc 24 participants Est. completion 2016-06-26 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Terminated NCT NCT02763007
An Extension Study of PEAK Trial
Not yet reported Kun-Ho Yoon 41 participants Est. completion 2019-02-28 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02765347
The Effects of Metformin on Glycemic Control and Insulin Sensitivity in Adolescents With T1DM
Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 30 participants Est. completion 2018-01 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02769481
Safety and Efficacy of Bexagliflozin Compared to Glimepiride as Add-on Therapy to Metformin in Type 2 Diabetes Subjects
Not yet reported Theracos 426 participants Est. completion 2019-06-14 45 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02773927
Combination of Metformin/Inulin vs Inulin on Adiponectin in Metabolic Syndrome
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 40 participants Est. completion 2015-06 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT02778776
Combination of Metformine/Inulin Versus Metformin on Prostate Benign Hyperplasia in Metabolic Syndrome
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 40 participants Est. completion 2015-06 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT02783053
Metformin and Core Temperature in Obese and Lean Males
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 18 participants Est. completion 2016-06 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02786823
Effect of Folic Acid and Vitamin B12 Supplementation in Subjects With Type 2 Diabetes
Not yet reported, Not yet reported All India Institute of Medical Sciences, Bhubaneswar 80 participants Est. completion 2017-09-15 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02787551
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period
Not yet reported Sanofi 514 participants Est. completion 2018-11-17 124 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02791490
A Study of the Safety and Efficacy of Sitagliptin Addition During Metformin Up-titration (MK-0431-848)
Not yet reported Merck Sharp & Dohme LLC 458 participants Est. completion 2018-02-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02793505
Safety of Metformin in Pregnancy
Centre Hospitalier Universitaire Vaudois 950 participantsOther conditions: Pregnancy, Pregestational Diabetes, Polycystic Ovary SyndromView official trial listing → -
Completed NCT NCT02794792
A Study to Assess the Efficacy and Safety of Ipragliflozin in Subjects With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin
Not yet reported Astellas Pharma Europe B.V. 268 participants Est. completion 2017-06-20 14 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT02796144
MEtformin and Lorcaserin for WeighT Loss in Schizophrenia
Not yet reported University of North Carolina, Chapel Hill 71 participants Est. completion 2020-02-14 4 sitesOther conditions: Schizophrenia, Schizoaffective Disorder, OverweightView official trial listing → -
Completed NCT NCT02798172
The Effect of Alogliptin on Pulmonary Function in Obese Patients With Type 2 Diabetes Inadequately Controlled by Metformin Monotherapy
Not yet reported Fourth People's Hospital of Shenyang 81 participants Est. completion 2015-08 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02802215
Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome
Not yet reported, Not yet reported Ain Shams University 80 participants Est. completion 2016-09 1 siteOther conditions: Polycystic Ovary Syndrome, Diabetes, GestationalView official trial listing → -
Completed NCT NCT02803918
A Study on Safety, Pharmacokinetics and Pharmacodynamics of Lixisenatide in Pediatric Patients With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Sanofi 23 participants Est. completion 2020-01-27 11 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02805283
Dapagliflozin Patient Satisfaction Survey
AstraZeneca 653 participants Est. completion 2018-10-29 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02810132
Effects of Metformin Treatment on Myocardial Efficiency in Patients With Heart Failure
Not yet reported Aarhus University Hospital 36 participants Est. completion 2018-02-14 1 siteHeart failureView official trial listing → -
Completed NCT NCT02813863
The Drug-drug Interaction of SP2086 and Metformin
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 24 participants Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT02815397
DA-EPOCH-Rituximab/Metformin (RM) for Double Hit Lymphoma
Not yet reported Rush University Medical Center 2 participants Est. completion 2016-07 1 site Stand-aloneOther conditions: Diffuse Large B-Cell LymphomaView official trial listing → -
Terminated NCT NCT02819869
The Combination Effect of Statin Plus Metformin on Relapse-free
Not yet reported Taipei Medical University WanFang Hospital 3 participants Est. completion 2016-12-14 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT02821910
Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Linagliptin/Metformin Extended Release Compared With Single Tablets
Not yet reported Boehringer Ingelheim 50 participants Est. completion 2016-10-31 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02823691
The MetNET-2 Trial
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 20 participants Est. completion 2021-12 1 site Stand-aloneOther conditions: Neuroendocrine TumorsView official trial listing → -
Status unknown NCT NCT02823808
Effect of Alogliptin/Pioglitazone on the Preservation of Long-term Beta-cell Function
Not yet reported Kyunghee University Medical Center 96 participants Est. completion 2021-12 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02824003
Study to Evaluate the Effect of ISIS GCGRRx on Hepatic Lipid and Glycogen Content in Type 2 Diabetes
Not yet reported Ionis Pharmaceuticals, Inc. 15 participants Est. completion 2017-05-22 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02827903
Metformin/Rosuvastatin Combination Therapy With in Patients With Type 2 Diabetes and Dyslipidemia
Not yet reported Jeil Pharmaceutical Co., Ltd. 237 participants Est. completion 2018-03-16 33 sites Stand-aloneType 2 diabetes Other conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT02831361
Trial to Evaluate the Efficacy and Safety of Gemigliptin Compared With Placebo Added on Insulin Alone or on Insulin in Combination With Metformin in Type 2 DM (ZEUS II Study)
Not yet reported LG Life Sciences 290 participants Est. completion 2018-02-08 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02836704
Comparison of Standard vs Higher Starting Dose of Insulin Glargine in Chinese Patients With Type 2 Diabetes (Glargine Starting Dose)
Not yet reported Sanofi 892 participants Est. completion 2018-04-26 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02844153
Metformin Use in Chronic Kidney Disease: The CKD-Met Study
Hospices Civils de Lyon 1000 participants Est. completion 2020-03 1 siteType 2 diabetesChronic kidney diseaseView official trial listing → -
Status unknown NCT NCT02844803
Study of Metformin and S. Baicalensis Combination Therapy in Type 2 Diabetes Mellitus Patients
Not yet reported Namyi Gu 20 participants 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02846233
Stepping-down Approach in Patients With Chronic Poorly-controlled Diabetes on Advanced Insulin Therapy?
Not yet reported University of California, San Francisco 22 participants Est. completion 2018-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02846506
A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Co-administered With Canagliflozin in Healthy Fed and Fasted Participants
Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-10 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT02848508
Metformin in Moderate and Severe Renal Failure (CKD 3-4): A Follow-up Study
Not yet reported Centre Hospitalier Universitaire, Amiens Est. completion 2017-06-07 1 site Stand-aloneOther conditions: Renal Insufficiency, ChronicView official trial listing → -
Status unknown NCT NCT02848950
The Effect of Metformin on Fecundability in an ART(Assisted Reproductive Technology) Setting - the Correlation to Uterine Flows
Not yet reported The Baruch Padeh Medical Center, Poriya 100 participants Est. completion 2017-07Other conditions: Infertility FemaleView official trial listing → -
Completed NCT NCT02851095
A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release (XR) With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants
Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02851212
A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin Extended Release Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants
Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-10 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02853630
A Clinical Trial to Study the Effects of Two Drugs, Vildagliptin and Metformin in Patients With Type 2 Diabetes Mellitus
Not yet reported India Diabetes Research Foundation & Dr. A. Ramachandran's Diabetes Hospitals 203 participants Est. completion 2018-12 6 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02854527
Transporter Cocktail Mutual Interaction
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2016-11-19 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02856113
Phase 3 Alogliptin Pediatric Study
Not yet reported Takeda 152 participants Est. completion 2022-02-14 67 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02865668
A Study to Assess the Bioequivalence of the Metformin Component of the Fixed Dose Combination Tablet of Canagliflozin and Metformin Extended Release With Respect to Metformin XR Tablet Coadministered With Canagliflozin in Healthy Fed and Fasted Participants
Not yet reported Janssen Research & Development, LLC 44 participants Est. completion 2016-10 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02866786
The Effects of OCP and Metformin on Clinical, Hormonal, Metabolic and Ultrasonographic Characteristics in PCOS
Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2017-08-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02872818
Apoptotic Signaling Pathways in Rats With Endometrial Hyperplasia
Not yet reported Kayseri Education and Research Hospital 40 participants Est. completion 2015-03 1 siteOther conditions: Apoptotic Signal Pathways in Endometrial HyperplasiaView official trial listing → -
Terminated NCT NCT02874430
Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 29 participants Est. completion 2020-12-11 1 site Stand-aloneObstructive sleep apnea Other conditions: Breast Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Uterine Corpus CancerView official trial listing → -
Completed NCT NCT02875821
Effects of Ipragliflozin on Excessive Fat in Type 2 Diabetes Patients With Non-alcoholic Fatty Liver Disease Treated With Metformin and Pioglitazone
Not yet reported Yonsei University 44 participants Est. completion 2017-06-07 1 siteMASLDType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT02879409
HbA1c Variability in Type II Diabetes
Not yet reported Weill Cornell Medical College in Qatar 150 participants Est. completion 2026-10-01 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Withdrawn NCT NCT02881528
Autoimmune Diabetes Accelerator Prevention Trial
Not yet reported University of Exeter Est. completion 2017-12-22 5 sites Stand-aloneOther conditions: Prediabetic StateView official trial listing → -
Status unknown NCT NCT02882477
Treatment of Wolfram Syndrome Type 2 With the Chelator Deferiprone and Incretin Based Therapy
Not yet reported, Not yet reported Hadassah Medical Organization 20 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: Diabetes Mellitus, Iron Metabolism Disorders, Gastroduodenal Ulcer, Optic Atrophy, Sensorineural Hearing Loss, Platelet DysfunctionView official trial listing → -
Completed NCT NCT02882581
Metformin in Breast Cancer, Visualized With Positron Emission Tomography
Not yet reported Aarhus University Hospital 7 participants Est. completion 2017-10 2 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02884089
A Study of the Effect of Abemaciclib on Metformin and Iohexol in Healthy Participants
Not yet reported Eli Lilly and Company 40 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02887625
Exenatide Plus Pioglitazone Versus Insulin in Poorly Controlled T2DM
Not yet reported Dr. Muhammad Abdulghani 410 participants Est. completion 2017-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02895750
Efficacity and Safety of Metformin XR in CKD Stage 1 to 3
Not yet reported Centre Hospitalier Universitaire, Amiens 12 participants Est. completion 2022-10-10 1 site Stand-aloneOther conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT02897349
Linagliptin Add-on to Insulin Background Therapy
Not yet reported Boehringer Ingelheim 206 participants Est. completion 2019-01-18 25 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02903511
Feasibility Study of Metformin Therapy in ADPKD
Not yet reported University of Colorado, Denver 56 participants Est. completion 2020-08-17 1 site Stand-aloneOther conditions: Polycystic Kidney, Autosomal DominantView official trial listing → -
Completed NCT NCT02909933
Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of Obesity
Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2015-10 1 site Added to GLP-1Other conditions: Polycystic Ovary Syndrome, ObesityView official trial listing → -
Completed NCT NCT02910817
Impact of Metformin on In Vitro Fertilization Outcomes in Overweight and Obese PCOS Women
Not yet reported Assiut University 102 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02911792
Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With Hyperfiltration
Not yet reported The University of Texas Health Science Center at San Antonio 72 participants Est. completion 2023-07-11 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02911948
A Double-blinded Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide and Insulin Degludec Both in Combination With Metformin in Japanese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal or Pre-mix/Combination Insulin Therapy and Oral Anti-diabetic Drugs
Not yet reported Novo Nordisk A/S 210 participants Est. completion 2017-11-22 38 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02919345
Assessment of Dapagliflozin Effect on Diabetic Endothelial Dysfunction of Brachial Artery
Not yet reported University of Campinas, Brazil 98 participants Est. completion 2019-03 1 site Stand-aloneType 2 diabetesCardiovascular disease Other conditions: Carotid Artery DiseasesView official trial listing → -
Completed NCT NCT02920801
Study About Effect of Saxagliptin on Circulating Endothelial Progenitor Cells and Endothelial Function in Newly Diagnosed Type 2 Diabetic Patients
Not yet reported Shanghai Zhongshan Hospital 31 participants Est. completion 2015-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02922179
Descriptive Analysis of Long- and Intermediate-Acting Insulin in Adult Diabetics
Biologics & Biosimilars Collective Intelligence Consortium 103951 participants Est. completion 2019-01Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02924064
Efficacy and Safety of Teneligliptin in Combination With Metformin in Chinese Patients With Type 2 Diabetes Mellitus
Not yet reported Tanabe Pharma Corporation 247 participants 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02926950
Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus on Background of Metformin
Not yet reported Lexicon Pharmaceuticals 518 participants Est. completion 2019-03-22 93 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT02931253
Metformin as an Upstream Therapy in Atrial Fibrillation
Not yet reported The Guthrie Clinic 6 participants Est. completion 2018-07-10 1 site Stand-aloneOther conditions: Atrial FibrillationView official trial listing → -
Status unknown NCT NCT02931591
Effect of Insulin Sensitization on IGF-1 Response to Growth Hormone in SGA Children
Not yet reported Cambridge University Hospitals NHS Foundation Trust 24 participants Est. completion 2020-06Other conditions: Small for Gestational AgeView official trial listing → -
Terminated NCT NCT02932475
Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD)
Not yet reported University of North Carolina, Chapel Hill 831 participants Est. completion 2022-06-15 10 sitesOther conditions: Diabetes, PregnancyView official trial listing → -
Completed NCT NCT02941367
Safety Assessment of Lyxumia (Lixisenatide) and Sulfonylurea as Add-on Treatment to Basal Insulin in Uncontrolled Patients With Type 2 Diabetes Mellitus Who Elect to Fast During Ramadan
Not yet reported Sanofi 184 participants Est. completion 2017-08-04 16 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02941445
Weight Maintenance With Dipeptidyl Peptidase 4 (DPP4) Inhibitor Sitagliptin in Combination With Metformin After Liragludite Induced Weight Loss
Not yet reported University Medical Centre Ljubljana 24 participants Est. completion 2016-08 Stand-aloneOther conditions: Polycystic Ovary Syndrome, Body WeightView official trial listing → -
Terminated NCT NCT02945813
SAKK 08/15 - PROMET - Salvage Radiotherapy +/- Metformin for Patients With Prostate Cancer After Prostatectomy
Not yet reported Swiss Cancer Institute 112 participants Est. completion 2022-02-28 27 sites Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Status unknown NCT NCT02946632
Effectiveness & Tolerability of Novel, Initial Triple Combination Therapy vs Conventional Therapy in Type 2 Diabetes
Not yet reported Korea University Anam Hospital 104 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Terminated NCT NCT02946996
Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy
Not yet reported Medical University of South Carolina 41 participants Est. completion 2024-08-19 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT02947620
Metformin/Atorvastatin Combination Therapy in Subjects With Type II Diabetes and Dyslipidemia (Phase 3)
Not yet reported Daewoong Pharmaceutical Co. LTD. 185 participants Est. completion 2017-02-27 1 siteOther conditions: Type II Diabetes, DyslipidemiaView official trial listing → -
Completed NCT NCT02948283
Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia
Not yet reported City of Hope Medical Center 3 participants Est. completion 2017-12-01 1 site Stand-aloneOther conditions: Anemia, Fatigue, Fever, Lymphadenopathy, Lymphocytosis, Night Sweats, Recurrent Chronic Lymphocytic Leukemia, Recurrent Plasma Cell Myeloma, Refractory Chronic Lymphocytic Leukemia, Refractory Plasma Cell Myeloma, Splenomegaly, Thrombocytopenia, Weight LossView official trial listing → -
Completed NCT NCT02949193
Efficacy and Safety of Evogliptin add-on to Metformin in Patients With type2 Diabetes
Not yet reported Dong-A ST Co., Ltd. 222 participants Est. completion 2015-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02949700
Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma
Not yet reported, Not yet reported Baylor College of Medicine 26 participants Est. completion 2022-07-07 3 sites Stand-aloneOther conditions: Head and Neck Squamous Cell CarcinomaView official trial listing → -
Completed NCT NCT02951260
The Effects of Metformin on Self-selected Exercise Intensity, Physical Fitness and Exercise-induced AMPK-activation
Not yet reported Rigshospitalet, Denmark 15 participants Est. completion 2017-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02954692
A Study to Evaluate the Effectiveness and Safety Initiation and Titration of Insulin Glargine (U300) in Insulin-naïve Patients With Type 2 Diabetes Mellitus (T2DM) Controlled on Oral Antidiabetic Drug Treatment in Turkey
Not yet reported Sanofi 112 participants Est. completion 2017-12-22 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02956044
Interaction of Bexagliflozin With Metformin, Glimepiride and Sitagliptin
Not yet reported Theracos 54 participants Est. completion 2017-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02960659
Title: Therapeutic Targets in African-American Youth With Type 2 Diabetes
Not yet reported, Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 24 participants Est. completion 2022-05-20 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02960711
Metformin and Dietary Restriction to Prevent Age-related Morbid Events in People With Metabolic Syndrome
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 1600 participants Est. completion 2019-07 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT02964247
LIRA-ADD2SGLT2i - Liraglutide Versus Placebo as add-on to SGLT2 Inhibitors.
Not yet reported Novo Nordisk A/S 303 participants Est. completion 2018-05-08 82 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT02967276
Clinical Activity of Metformin With High-dose of Dexamethasone in Relapse Multiple Myeloma
Not yet reported University of Campinas, Brazil 28 participants Est. completion 2020-02 2 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT02972723
Metformin Therapy in HCV Infection
Not yet reported Nottingham University Hospitals NHS Trust 16 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Chronic Hepatitis C InfectionView official trial listing → -
Completed NCT NCT02973321
A Study to Assess the Safety and Efficacy of SAR425899 in Patients With Type 2 Diabetes Mellitus
Not yet reported Sanofi 296 participants Est. completion 2017-12-27 59 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02978547
The Effects of Neoadjuvant Metformin on Tumour Cell Proliferation and Tumour Progression in Pancreatic Ductal Adenocarcinoma
Not yet reported British Columbia Cancer Agency 20 participants Est. completion 2021-01 1 site Stand-aloneOther conditions: Resectable Pancreatic Ductal AdenocarcinomaView official trial listing → -
Completed NCT NCT02980276
RCT Metformin for Reduction of Gestational Diabetes Mellitus Effects
Not yet reported National University of Ireland, Galway, Ireland 535 participants Est. completion 2023-04-13 2 sitesOther conditions: Gestational DiabetesView official trial listing → -
Status unknown NCT NCT02981121
Hospital-based Diabetes Prevention Study in Korea
Not yet reported Jeong-taek Woo 744 participants Est. completion 2020-11 1 sitePrediabetesView official trial listing → -
Completed NCT NCT02981329
Fetal Hemoglobin Induction Treatment Metformin
Not yet reported Baylor College of Medicine 37 participants Est. completion 2020-07-20 2 sites Stand-aloneOther conditions: Sickle Cell Anemia, Sickle Cell Disease, Hemoglobin DisorderView official trial listing → -
Completed NCT NCT02982798
The PK Characteristics of the Co-administration of Metformin SR and Rosuvastatin and JLP-1310 in Healthy Male Volunteers
Not yet reported Jeil Pharmaceutical Co., Ltd. 40 participants Est. completion 2018-01-31 1 site Stand-aloneOther conditions: Diabetes, HyperlipidemiaView official trial listing → -
Status unknown NCT NCT02984475
The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia Major
Not yet reported Cairo University 60 participants Est. completion 2019-04 2 sitesOther conditions: Beta Thalassemia Major AnemiaView official trial listing → -
Status unknown NCT NCT02984722
Extended-release vs Immediate-release Metformin in PCOS Women
Not yet reported Catholic University of the Sacred Heart 80 participants 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02986659
Genomic Outcomes of Metformin
Not yet reported Wake Forest University Health Sciences 30 participants Est. completion 2018-11-15 1 siteCardiovascular disease Other conditions: Mild Cognitive Impairment, Obesity, Abdominal, HypertensionView official trial listing → -
Terminated NCT NCT02989649
Non-Interventional Study of the Use of Alogliptin and Alogliptin Fixed-Dose Combinations With Pioglitazone and With Metformin in Standard Clinical Practice
Takeda 593 participants Est. completion 2018-01-26 11 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT02990728
Mirena® ± Metformin as Fertility-preserving Treatment for Young Asian Women With Early Endometrial Cancer
Not yet reported Chang Gung Memorial Hospital 120 participants Est. completion 2020-03 Stand-aloneOther conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT03004612
Effect of Linagliptin + Metformin vs Metformin Alone in Patients With Prediabetes
Not yet reported Universidad de Guanajuato 144 participants Est. completion 2019-06 1 site Stand-aloneOther conditions: Prediabetic State, Insulin ResistanceView official trial listing → -
Active, not recruiting NCT NCT03006172
To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer
Not yet reported Genentech, Inc. 200 participants Est. completion 2026-12-31 12 sites Stand-aloneOther conditions: Breast Cancer, Solid TumorView official trial listing → -
Completed NCT NCT03008551
Empagliflozin vs Metformin in PCOS
Not yet reported, Not yet reported Hull University Teaching Hospitals NHS Trust 40 participants Est. completion 2018-04-02 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT03010683
Effects of Agonists of Glucagon Like Peptide - 1 Receptors (GLP-1R) on Arterial Stiffness, Endothelial Glycocalyx and Coronary Flow Reserve in Patients With Coronary Artery Disease and Patients With Diabetes Mellitus
Not yet reported University of Athens 60 participants Est. completion 2017-12 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT03017833
Sapanisertib and Metformin in Treating Patients With Advanced or Metastatic Relapsed or Refractory Cancers
Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2022-12-21 1 site Stand-aloneOther conditions: Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Refractory NeoplasmView official trial listing → -
Status unknown NCT NCT03018665
A Study of the Effect of Glucagon-like Peptide 1(GLP-1) Receptor Agonist in Combination With Metformin Therapy on Diabetes Remission in Subjects With Newly Diagnosed Type 2 Diabetes Who Are Overweight or Obese
Not yet reported The First Hospital of Jilin University 200 participants 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT03029390
Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes
Not yet reported University of Guadalajara 28 participants Est. completion 2023-12 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT03029702
Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus
Not yet reported Maisa N. Feghali, MD 54 participants Est. completion 2023-08-31 1 siteOther conditions: Gestational Diabetes, Diabetes, Gestational, Pregnancy in DiabetesView official trial listing → -
Completed NCT NCT03030300
Remission Rate of Newly Diagnosed Type 2 Diabetes Outpatients Treated With Short-term Intensive Insulin Therapy
Not yet reported Qianfoshan Hospital 170 participants Est. completion 2015-02 3 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT03031821
Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome
Not yet reported Canadian Urologic Oncology Group 166 participants Est. completion 2023-11-24 16 sites Stand-aloneMetabolic syndrome Other conditions: Prostate CancerView official trial listing → -
Completed NCT NCT03034941
Short Term Weight Loss With Liraglutide and Metformin in Infertile Obese PCOS Patients
Not yet reported University Medical Centre Ljubljana 35 participants Est. completion 2016-12 1 siteOther conditions: Obesity, PCOSView official trial listing → -
Completed NCT NCT03038789
XIGDUO Extended Release (XR) Post Marketing Surveillance
AstraZeneca 623 participants Est. completion 2019-08-30 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03039075
Metformin SR Tablet (DuLeNing) and Glucophage in Patients With Type 2 Diabetes
Not yet reported Chongqing Medical University 240 participants Est. completion 2018-11 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT03041129
Post-Prandial Liver Glucose Metabolism in PCOS
University of Colorado, Denver 19 participants Est. completion 2018-09-29 1 siteOther conditions: Polycystic Ovarian Syndrome, Obesity, Hepatic SteatosisView official trial listing → -
Terminated NCT NCT03047837
A Randomized, 2x2 Factorial Design Biomarker Prevention Trial of Low-dose ASA and Metformin in Stage I-III Crc Patients
Not yet reported Ente Ospedaliero Ospedali Galliera 160 participants Est. completion 2024-03-31 1 site Stand-aloneOther conditions: Tertiary Prevention in Colon CancerView official trial listing → -
Status unknown NCT NCT03048500
Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery
Not yet reported Northwestern University 17 participants Est. completion 2021-09 2 sites Stand-aloneOther conditions: Recurrent Non-Small Cell Lung Carcinoma, Stage III Non-Small Cell Lung Cancer, Stage IIIA Non-Small Cell Lung Cancer, Stage IIIB Non-Small Cell Lung Cancer, Stage IV Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT03049228
In and ex Vivo Mitochondrial Function of the Heart
Maastricht University Medical Center 38 participants Est. completion 2020-03-02 1 siteType 2 diabetes Other conditions: Diabetic CardiomyopathiesView official trial listing → -
Completed NCT NCT03050619
Characteristics of Empagliflozin Initiators
Boehringer Ingelheim 31908 participants Est. completion 2016-10-14 1 siteType 2 diabetesView official trial listing → -
Suspended NCT NCT03051451
Fixed Dose Combination of Fluoxetin and Metformin in the Management of Overweight and Obesity
Not yet reported Laboratorios Silanes S.A. de C.V. 150 participants Est. completion 2018-11 1 siteOther conditions: Overweight and ObesityView official trial listing → -
Terminated NCT NCT03053518
Validation of Machine Learning Based Personalized Nutrition Algorithm to Reduce Postprandial Glycemic Excursions Among North American Individuals With Newly Diagnosed Type 2 Diabetes
Not yet reported NYU Langone Health 22 participants Est. completion 2018-01-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03054519
Improve PAD PERformance With METformin
Not yet reported Northwestern University 202 participants Est. completion 2025-11-01 5 sitesOther conditions: Peripheral Artery DiseaseView official trial listing → -
Status unknown NCT NCT03056274
Metformin in Intrahepatic Cholestasis of Pregnancy
Not yet reported, Not yet reported Epsom and St Helier University Hospitals NHS Trust 40 participants Est. completion 2019-09Other conditions: Intrahepatic Cholestases, Pregnancy ComplicationsView official trial listing → -
Terminated NCT NCT03060980
Comparison of Efficacy, Safety, and Tolerability of ITCA 650 to Empagliflozin and Glimepiride as add-on Metformin
Not yet reported Intarcia Therapeutics 245 participants Est. completion 2018-01-26 101 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03061214
Efficacy and Safety of Semaglutide Once-weekly Versus Sitagliptin Once-daily as add-on to Metformin in Subjects With Type 2 Diabetes (SUSTAIN - CHINA MRCT)
Not yet reported Novo Nordisk A/S 868 participants Est. completion 2019-04-15 67 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03061981
A Study To Evaluate The Safety,Tolerability, PK and PD Of DA-1241 In Healthy Male Subjects
Not yet reported Dong-A ST Co., Ltd. 60 participants Est. completion 2017-10-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03066830
Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus on Background of Sulfonylurea Alone or With Metformin
Not yet reported Lexicon Pharmaceuticals 507 participants Est. completion 2019-04-30 76 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03068065
Antidiabetic Effects on Intrahepatic Fat
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 87 participants Est. completion 2015-10 1 siteType 2 diabetes Other conditions: Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Status unknown NCT NCT03071705
Metformin Plus TKI Use in Patients With Non-Small Cell Lung Carcinoma
Not yet reported Instituto Nacional de Cancerologia de Mexico 120 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: Non-Small Cell Adenocarcinoma, Tyrosine Kinase Mutation, EGFR Gene MutationView official trial listing → -
Completed NCT NCT03072485
Phase 1 Study of the Effects of Combining Topical FDA-approved Drugs on Age-related Pathways on the Skin of Healthy Volunteers
Not yet reported Anne Chang 10 participants Est. completion 2019-02-22 1 siteOther conditions: AgingView official trial listing → -
Completed NCT NCT03076112
Efficacy of Ipragliflozin Compared With Sitagliptin in Uncontrolled Type 2 Diabetes With Sulfonylurea and Metformin
Not yet reported Seoul National University Bundang Hospital 170 participants Est. completion 2022-08-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT03076281
Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 7 participants Est. completion 2018-12-03 1 site Stand-aloneOther conditions: Larynx, LIP, Oral Cavity, PharynxView official trial listing → -
Withdrawn NCT NCT03078725
Failure Rate of GLyburide And Metformin Among Gestational Diabetics
Not yet reported The University of Texas Health Science Center, Houston Est. completion 2018-05-10Other conditions: Gestational Diabetes Mellitus, Class A2View official trial listing → -
Completed NCT NCT03086005
Study to Assess the Effect of Metformin Supplementation on IVF Outcome in Patients With Polycystic Ovarian Syndrome.
Not yet reported Chung-Hoon Kim 24 participants Est. completion 2015-07-23 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT03088631
Metformin in Intracytoplasmic Sperm Injection Cycles
Not yet reported Assiut University 320 participants Est. completion 2019-04-01 1 siteOther conditions: Intracytoplasmatic Sperm InjectionView official trial listing → -
Completed NCT NCT03088670
Efficacy and Safety of Gosogliptin as Monotherapy and in Combination With Metformin vs. Vildagliptin as Monotherapy and in Combination With Metformin in Drug-naive Type 2 Diabetic Patients.
Not yet reported SatRx LLC 299 participants Est. completion 2014-10-03 27 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03098654
Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care in Kisarawe, Tanzania
Not yet reported Medical University of South Carolina 214 participants Est. completion 2022-08-05 1 siteType 2 diabetes Other conditions: Human Immunodeficiency Virus, HypertensionView official trial listing → -
Completed NCT NCT03106870
Adding Metformin to Insulin in Controlling Pregestational and Gestational Diabetes Mellitus
Not yet reported Ain Shams University 62 participants Est. completion 2016-12Other conditions: Gestational Diabetes Mellitus in PregnancyView official trial listing → -
Active, not recruiting NCT NCT03107884
Role of Metformin on Muscle Health of Older Adults
Not yet reported University of Utah 64 participants Est. completion 2026-11-01 1 site Stand-aloneOther conditions: Muscle Atrophy, Insulin ResistanceView official trial listing → -
Completed NCT NCT03108963
L-carnitine and Metformin in Obese PCOS Women.
Not yet reported Zagazig University 280 participants Est. completion 2018-03 1 site Stand-aloneOther conditions: PCOSView official trial listing → -
Completed NCT NCT03109873
Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 9 participants Est. completion 2020-07-31 1 site Stand-aloneOther conditions: Larynx, Lip, Oral Cavity, PharynxView official trial listing → -
Completed NCT NCT03115112
Safety and Efficacy of Bexagliflozin Compared to Sitagliptin as Add-on Therapy to Metformin in Type 2 Diabetes Subjects
Not yet reported Theracos 386 participants Est. completion 2018-10-31 56 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03117517
Treatment With Metformin and Combination of Metformin and Pioglitazone in Polycystic Ovarian Syndrome
Not yet reported Khyber Medical University Peshawar 106 participants Est. completion 2018-03-07 1 site Stand-aloneOther conditions: Polycystic Ovarian SyndromeView official trial listing → -
Terminated NCT NCT03118713
A Study to Evaluate the Renal Protective Effect (Urine Albumin-to-Creatinine Ratio (UACR)), Efficacy and Safety of Ipragliflozin in Type 2 Diabetes Mellitus Patients With Albuminuria
Not yet reported Astellas Pharma Korea, Inc. 33 participants Est. completion 2018-12-12 8 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03122041
Sitagliptin Improved Beta Cell Function and Prevented a Conversion Rate to Impaired Glucose Tolerance and Type 2 Diabetes in Metformin Intolerant Obese Women With Polycystic Ovary Syndrome
Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2016-11Other conditions: PCOSView official trial listing → -
Completed NCT NCT03122769
Cardiac Uptake of Metformin, Visualized by Positron Emission Tomography
Not yet reported Henrik Wiggers 6 participants Est. completion 2018-04-10 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT03125694
Sitagliptin vs. Pioglitazone as add-on Treatments in Patients With Type 2 Diabetes Uncontrolled on the Full-dose Metformin Plus Sulfonylurea
Not yet reported Tehran University of Medical Sciences 250 participants Est. completion 2017-04-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03129113
Adding MAraViroc &/or METformin for Hepatic Steatosis in People Living With HIV
Not yet reported, Not yet reported University College, London 90 participants Est. completion 2020-11-06 6 sites Stand-aloneOther conditions: Hepatic Steatosis, HIV-1-infectionView official trial listing → -
Completed NCT NCT03130426
Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IGlarLixi
Not yet reported Population Health Research Institute 161 participants Est. completion 2020-09-30 8 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03135301
Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome
Not yet reported Assiut University 80 participants Est. completion 2024-03 1 site Stand-aloneOther conditions: Infertility, FemaleView official trial listing → -
Completed NCT NCT03136484
Efficacy and Safety of Semaglutide Versus Canagliflozin as add-on to Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 788 participants Est. completion 2018-11-16 119 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT03137186
Repurposing Metformin as Anticancer Drug: in Advanced Prostate Cancer
Not yet reported Mansoura University 120 participants Est. completion 2020-01 1 siteOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT03138356
Bioequivalence Study of Combination Tablets of Saxagliptin / Dapagliflozin / Metformin XR (Extended-release) and Dapagliflozin / Metformin XR Relative to Individual Components in Healthy Subjects
Not yet reported AstraZeneca 126 participants Est. completion 2017-11-28 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03141073
Long-term Efficacy and Safety of HMS5552 add-on to Metformin in T2DM Subjects
Not yet reported Hua Medicine Limited 767 participants Est. completion 2021-02-28 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03151005
The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS
Not yet reported Xinqiao Hospital of Chongqing 70 participants Est. completion 2021-04-23 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome (PCOS), Overweight, ObesityView official trial listing → -
Terminated NCT NCT03151772
Bioavailability of Disulfiram and Metformin in Glioblastomas
Not yet reported Sahlgrenska University Hospital 3 participants Est. completion 2020-09-24 1 site Stand-aloneOther conditions: GlioblastomaView official trial listing → -
Completed NCT NCT03165877
Effect of Low-glycemic Index Meals Intake on DM2 Women Under Metformin Therapy
Not yet reported Universidad de Valparaiso 13 participants Est. completion 2016-10-13Type 2 diabetesView official trial listing → -
Completed NCT NCT03167918
Lung Function in Patients With Early Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Liaoning University of Traditional Chinese Medicine 200 participants Est. completion 2017-05-01 Stand-aloneType 2 diabetes Other conditions: Pulmonary FunctionView official trial listing → -
Completed NCT NCT03169959
A Study to Evaluate the Food Effect on Drug Availability, Pharmacokinetic (PK) Properties, Safety and Tolerability of Two Different Dose Combination Therapy of Saxagliptin/Dapagliflozin/Metformin Extended-release (XR) Against Individual Component Co-administration.
Not yet reported AstraZeneca 85 participants Est. completion 2017-08-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03172494
A Trial Comparing Insulin Degludec/Liraglutide, Insulin Degludec, and Liraglutide in Chinese Subjects With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs (OADs)
Not yet reported Novo Nordisk A/S 720 participants Est. completion 2019-07-13 36 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03175120
A Trial Comparing Insulin Degludec/Liraglutide and Insulin Degludec in Combination With Metformin in Chinese Subjects With Type 2 Diabetes Mellitus Inadequately Controlled With Basal Insulin Therapy and Metformin With or Without One Other Oral Antidiabetic Drug (OAD)
Not yet reported Novo Nordisk A/S 453 participants Est. completion 2019-04-04 37 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03179254
Type 2 Diabetes and Ambulatory Surgery Patients
Not yet reported University of Texas Southwestern Medical Center 160 participants Est. completion 2014-08-26 Stand-aloneOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT03183752
Insulin Resistance and Metformin Use on Volume of Benign Thyroid Nodules
Not yet reported Hospital Universitário Clementino Fraga Filho 28 participants Est. completion 2019-04-17 1 site Stand-aloneOther conditions: Thyroid Nodule, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT03184493
Celebrex and Metformin for Postoperative Hepatocellular Carcinoma
Not yet reported Guangxi Medical University 200 participants Est. completion 2021-06 1 site Stand-aloneOther conditions: Liver CancerView official trial listing → -
Completed NCT NCT03189407
Effect of Moringa Oleifera on Metformin Plasma Level in Type 2 Diabetes Mellitus Patients
Not yet reported Titilayo O Fakeye 25 participants Est. completion 2016-04-30Type 2 diabetesView official trial listing → -
Completed NCT NCT03189732
Effect of Metformin on Exercise-induced Lipolysis
Not yet reported Charles University, Czech Republic 10 participants Est. completion 2018-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03192293
Metformin and Simvastatin in Addition to Fulvestrant
Not yet reported National University Hospital, Singapore 28 participants Est. completion 2019-01-20 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT03194009
PRuDENTE; Diabetes Prevention Via Exercise, Nutrition and Treatment
Not yet reported Instituto Nacional de Salud Publica, Mexico 3060 participants Est. completion 2022-12-31 1 siteType 2 diabetes Other conditions: Prediabetic StateView official trial listing → -
Completed NCT NCT03194945
Effects of Sequential Treatment Based on Lina/MET After Short-term Intensive Insulin in Newly Diagnosed Type 2 Diabetes
Not yet reported Sun Yat-sen University 412 participants Est. completion 2022-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03196154
Association Between Insulin Resistance and Beta Cell Function With HbA1C in Diabetics
Clinical Research Centre, Malaysia 255 participants Est. completion 2018-03-30 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03196362
Impacts of PIO/MET Following Short-term Intensive Insulin Treatment in Newly Diagnosed Type 2 Diabetes
Not yet reported Sun Yat-sen University 50 participants Est. completion 2018-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03200015
Rituximab, Cyclophosphamide, Vincristine and Prednisone (R-CHOP) Plus Metformin in Diffuse Large-B-cell Lymphoma
Not yet reported Hospital Universitario Dr. Jose E. Gonzalez 15 participants Est. completion 2019-01-27 1 site Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Completed NCT NCT03202563
Trial to Evaluate the Efficacy on Glycemic Variability and Safety of Gemigliptin Compared With Dapagliflozin Added on Metformin Alone or Diabetes Medication Naïve Patient in Type 2 Diabetes Mellitus (Stable II Study)
Not yet reported LG Chem 71 participants Est. completion 2018-12-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03204058
Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 90 participants Est. completion 2017-02-23Other conditions: Chronic PeriodontitisView official trial listing → -
Completed NCT NCT03204071
Locally Delivered Metformin and Aloe Vera for Treatment of Intrabody Defects in Chronic Periodontitis
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 90 participants Est. completion 2017-02Other conditions: Chronic PeriodontitisView official trial listing → -
Status unknown NCT NCT03204799
Metagenomic Analysis of Human Gut Microbiota in Patients With Metabolic Diseases Including Diabetes
Yonsei University 150 participants Est. completion 2019-12-16 1 siteType 2 diabetes Other conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT03207698
PRF+1% MF for Class II Mandibular Furcation Defects
Not yet reported, Not yet reported Government Dental College and Research Institute, Bangalore 75 participants Est. completion 2016-05 1 siteOther conditions: Furcation DefectsView official trial listing → -
Completed NCT NCT03208309
Effect of Diacerein in the Metabolic Control of Patients With DM Type 2 and Secondary Failure to Metformin
Not yet reported ANS Pharma 40 participants Est. completion 2015-12 3 sitesType 2 diabetes Other conditions: Complications of Diabetes Mellitus, Diabetes MellitusView official trial listing → -
Completed NCT NCT03214380
A Study of LY900014 Compared to Insulin Lispro in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 933 participants Est. completion 2019-03-13 141 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03216278
The Purpose of the Study is to Compare Two Fixed Dose Combination Tablets of Dapagliflozin/Metformin XR in Healthy Subjects Under Fasting and Fed Conditions
Not yet reported AstraZeneca 284 participants Est. completion 2018-05-22 1 site Stand-aloneOther conditions: Healthy Subjects in Fasted and Fed StateView official trial listing → -
Status unknown NCT NCT03222765
Prevention of Microvascular Complications in Prediabetes e-PREDICE Study
Not yet reported Evidem Consultores SL 1000 participants Est. completion 2019-12-31 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT03225209
Medically Reproducing Bariatric Surgery
Not yet reported Moahad S Dar 5 participants Est. completion 2018-10-23 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03229057
Comparing the Effects of Oral Contraceptive Pills Versus Metformin
Not yet reported Anuja Dokras 240 participants Est. completion 2024-07-15 2 sites Stand-aloneOther conditions: PCOSView official trial listing → -
Completed NCT NCT03230786
Study to Evaluate the Efficacy and Safety of KBP-042 in Patients With Type 2 Diabetes
Not yet reported KeyBioscience AG 255 participants Est. completion 2018-07-31 30 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03235050
A Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 834 participants Est. completion 2019-06-14 119 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03236740
OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS
Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2018-03-15 1 siteOther conditions: PCOSView official trial listing → -
Status unknown NCT NCT03238495
Randomized Trial of Neo-adjuvant Chemotherapy With or Without Metformin for HER2 Positive Operable Breast Cancer
Not yet reported Qamar Khan 100 participants Est. completion 2023-06-01 6 sites Stand-aloneOther conditions: HER2-positive Breast CancerView official trial listing → -
Status unknown NCT NCT03239119
The Effectivity and Safety Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 456 participants Est. completion 2019-01-15Type 2 diabetesView official trial listing → -
Completed NCT NCT03243851
Study on Low Dose Temozolomide Plus Metformin or Placebo in Patient With Recurrent or Refractory Glioblastoma
Not yet reported Yong-Kil Hong 81 participants Est. completion 2020-12-31 12 sites Stand-aloneOther conditions: GlioblastomaView official trial listing → -
Completed NCT NCT03246451
The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D
Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2017-12-10 1 site Stand-aloneOther conditions: Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT03249506
Cardiovascular Outcomes in Participants With Type 2 Diabetes Mellitus (T2DM)
Janssen Research & Development, LLC 25358 participants Est. completion 2017-11-01 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03249896
Web/Smartphone-based Lifestyle Coaching Program in Pregnant Women With Gestational Diabetes
Not yet reported National University Hospital, Singapore 340 participants Est. completion 2019-05 1 siteOther conditions: Gestational Diabetes, Pregnancy Complications, Weight GainView official trial listing → -
Completed NCT NCT03253562
Metformin Versus Vildagliptin for Diabetic Hypertensive Patients
Not yet reported MTI University 120 participants Est. completion 2017-08-01 1 siteOther conditions: Reducing the Elevated Blood Pressure for Diabetic Hypertensive PatientsView official trial listing → -
Terminated NCT NCT03258723
Diabetes Prevention With Lifestyle Intervention and Metformin Escalation
Not yet reported Yale University 114 participants Est. completion 2021-12-01 4 sites Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT03259490
This Study Tests Whether Taking the Medicines Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills. The Study is Done in Healthy Men and Women and Measures the Amount of Each Medicine in the Blood
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2017-11-13 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03259789
Safety and Efficacy of Bexagliflozin Compared to Placebo as Add-on Therapy to Metformin in Type 2 Diabetes Subjects
Not yet reported Theracos 351 participants Est. completion 2019-01-23 43 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03259919
Metformin Treatment of Pregnant Women With Polycystic Ovary Syndrome: a Pilot Study
Not yet reported Norwegian University of Science and Technology 40 participants Est. completion 2003-03 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT03267576
An Efficacy Study of Canagliflozin or Sitagliptin to Determine Glucose Variability in Mexican Participants With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin
Not yet reported Janssen Research & Development, LLC 64 participants Est. completion 2018-10-01 5 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03268005
Research Study Comparing a New Medicine "Fast-acting Insulin Aspart" to Another Already Available Medicine "NovoRapid"/"NovoLog" in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1264 participants Est. completion 2019-01-29 167 sites Stand-aloneType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT03271866
Metformin Treatment on Cognitive Impairment of Schizophrenia Co-morbid Metabolic Syndrome
Not yet reported Central South University 80 participants Est. completion 2023-12-31 1 siteOther conditions: SchizophreniaView official trial listing → -
Status unknown NCT NCT03279263
An Add-on Study of MLR-1023 in Adults With Uncontrolled Type 2 Diabetes on Metformin Therapy
Not yet reported Melior Pharmaceuticals 400 participants Est. completion 2019-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03283657
Diabetes Risk Education and Communication Trial
Not yet reported Northwestern University 53 participants Est. completion 2019-03-17 1 site Stand-alonePrediabetesType 2 diabetes Other conditions: Diabetes Mellitus, Body Weight, Body Weight ChangesView official trial listing → -
Completed NCT NCT03297879
Comparison of Exenatide and Metformin Monotherapy in Overweight/Obese Patients With Newly Diagnosed Type 2 Diabetes
Not yet reported Beijing Chao Yang Hospital 230 participants Est. completion 2016-02-28 Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT03307252
This Study Tests the Effect of Certain Medicines on the Transport of Other Medicines in the Body of Healthy Men
Not yet reported Boehringer Ingelheim 45 participants Est. completion 2018-05-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03309007
A Double-Blind, Placebo-Controlled Trial of Anti-Aging, Pro-Autophagy Effects of Metformin in Adults With Prediabetes
Not yet reported University of New Mexico 25 participants Est. completion 2020-08-20 1 site Stand-alonePrediabetes Other conditions: AgingView official trial listing → -
Completed NCT NCT03310749
An Assessment of Pharmacokinetic Gemigliptin and Metformin Interactions in Healthy Mexican Volunteers
Not yet reported Stendhal Americas, S.A. 34 participants Est. completion 2016-05-03 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT03311308
A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma
Not yet reported Yana Najjar 23 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Advanced MelanomaView official trial listing → -
Completed NCT NCT03312582
Locally Delivered 1% Metformin Gel in Peri-implantitis
Not yet reported King Saud University 46 participants Est. completion 2017-07-24 Stand-aloneOther conditions: Peri-ImplantitisView official trial listing → -
Completed NCT NCT03316690
The Interaction Between Metformin and Physical Training
Not yet reported Kristian Karstoft 34 participants Est. completion 2018-10-01 1 site Stand-alonePrediabetesType 2 diabetesView official trial listing → -
Completed NCT NCT03317028
CS02 vs Placebo With Metformin in Type 2 Diabetes Mellitus (T2DM)
Not yet reported Center Laboratories, Inc. 201 participants Est. completion 2020-04-21 13 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03320694
Comparison of Metformin and Insulin for Management of Gestational Diabetes Mellitus
Not yet reported Services Institute of Medical Sciences, Pakistan 278 participants Est. completion 2017-06-30 1 site Stand-aloneOther conditions: Gestational Diabetes Mellitus in PregnancyView official trial listing → -
Completed NCT NCT03323294
Bioenergetics and Metabolism in Pediatric Populations
Arkansas Children's Hospital Research Institute 79 participants Est. completion 2024-06-30 1 siteType 2 diabetes Other conditions: Obesity, Insulin ResistanceView official trial listing → -
Completed NCT NCT03329651
The Interaction Between Metformin and Acute Exercise
Not yet reported Kristian Karstoft 34 participants Est. completion 2018-10-01 1 site Stand-alonePrediabetesType 2 diabetesView official trial listing → -
Terminated NCT NCT03331861
Metformin in Heart Failure Without Diabetes
Not yet reported Columbia University 6 participants Est. completion 2021-08-20 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT03332771
Efficacy and Safety of Sotagliflozin Versus Glimepiride and Placebo in Participants With Type 2 Diabetes Mellitus That Are Taking Metformin Monotherapy
Not yet reported Lexicon Pharmaceuticals 954 participants Est. completion 2019-09-06 142 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03335423
Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug Interactions
Not yet reported University of Southern Denmark 228 participants Est. completion 2020-06-13 1 site Stand-aloneOther conditions: Metformin, Organic Cation Transporter 1, CodeineView official trial listing → -
Status unknown NCT NCT03336840
Effect of Metformin and Probiotics in Reproductive-aged Patients With Polycystic Ovary Syndrome
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 90 participants Est. completion 2019-06 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT03349684
Loose-dose Combination of Acarbose and Metformin for T2DM in Metformin-failure Patients
Not yet reported Bayer 287 participants Est. completion 2019-08-21 29 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT03349775
Cardiometabolic Disease and Pulmonary Hypertension
Not yet reported Massachusetts General Hospital 21 participants Est. completion 2020-12-22 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03351478
Efficacy and Safety of Sotagliflozin Versus Placebo and Empagliflozin in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking a DPP4 Inhibitor Alone or With Metformin
Not yet reported Lexicon Pharmaceuticals 770 participants Est. completion 2019-05-16 160 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03352869
Research of Exenatide for Overweight/Obese PCOS Patients With IGR
Not yet reported RenJi Hospital 183 participants Est. completion 2018-07-31 1 site Added to GLP-1Other conditions: Polycystic Ovary Syndrome, Overweight and Obesity, Disorder of Glucose RegulationView official trial listing → -
Completed NCT NCT03353948
The Effect of a Liraglutide on IVF in Obese PCOS
Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2016-09-01Other conditions: Polycystic Ovary Syndrome, Obesity, Infertility, FemaleView official trial listing → -
Completed NCT NCT03355014
BE Study of the Combinations of Gemigliptin/Metformin HCl Extended Release 50/1000mg(25/500mg x 2 Tablets) in Comparison to Each Component Administered Alone
Not yet reported LG Chem 70 participants Est. completion 2018-01-12 1 site Stand-aloneOther conditions: Healthy Male VolunteersView official trial listing → -
Completed NCT NCT03355469
Exercise Dose and Metformin for Vascular Health in Metabolic Syndrome
Not yet reported, Not yet reported Rutgers University 91 participants Est. completion 2024-05-23 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT03359590
Sitagliptin and the Risk for Hypoglycaemia in Type 2 Diabetes Patients
Not yet reported Profil Institut für Stoffwechselforschung GmbH 20 participants Est. completion 2019-07-17 1 siteOther conditions: Pharmacological ActionView official trial listing → -
Completed NCT NCT03359681
Metformin Treatment for Colon Cancer
Not yet reported Zealand University Hospital 48 participants Est. completion 2021-10-04 1 siteOther conditions: Colon CancerView official trial listing → -
Completed NCT NCT03359837
Comparison of Two Treatment Regimens in Patients With Type 2 Diabetes After Short-term Intensive Insulin Therapy
Not yet reported Sanofi 384 participants Est. completion 2020-06-29 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03361878
Pharmacokinetics of Metformin Intolerance
Not yet reported NHS Tayside 20 participants Est. completion 2016-05-05Type 2 diabetes Other conditions: Metformin Adverse ReactionView official trial listing → -
Completed NCT NCT03363815
A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, Rosuvastatin, Metformin, Digoxin, and Nintedanib in Healthy Adult Subjects
Not yet reported Celgene 56 participants Est. completion 2018-07-29 1 site Stand-aloneOther conditions: Heathy VolunteerView official trial listing → -
Completed NCT NCT03364335
The Effect Of NS-0200 and NS-0300 Versus Placebo on Weight In Obesity
Not yet reported NuSirt Biopharma 267 participants Est. completion 2018-08-17 15 sitesOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT03375580
Therapeutic Effects of Compound Zhenzhu Tiaozhi Capsules in NAFLD
Not yet reported The First Affiliated Hospital of Guangdong Pharmaceutical University 196 participants Est. completion 2019-12-31 1 siteMASLDView official trial listing → -
Status unknown NCT NCT03377335
Dapagliflozin, Cardio-Metabolic Risk Factors and Type-2 Diabetes
Not yet reported University of Palermo 186 participants Est. completion 2019-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03378297
IMPACT: A Randomized WOO Study of Novel Therapeutic Agents in Women Triaged to Primary Surgery for EOC
Not yet reported Haukeland University Hospital 26 participants Est. completion 2023-01-05 2 sites Stand-aloneOther conditions: Ovarian CancerView official trial listing → -
Terminated NCT NCT03380091
Metformin, Vitamin D, and Depression in Polycystic Ovary Syndrome (PCOS) Trial
Not yet reported University of California, San Francisco 5 participants Est. completion 2019-09-01 1 site Stand-aloneOther conditions: PCOS, Depression, Vitamin D Deficiency, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT03383068
Research of Intensive Metabolic Intervention Before Pregnancy in PCOS
Not yet reported RenJi Hospital 160 participants Est. completion 2020-06-30 1 site MixedPrediabetes Other conditions: PCOSView official trial listing → -
Completed NCT NCT03393208
Glucophage Immediate Release (GIR) China Bioequivalence Study
Not yet reported Merck KGaA, Darmstadt, Germany 44 participants Est. completion 2018-01-29 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03398356
Metformin and Its Impact on the Substances Associated With NO Production in Prediabetes Patients.
Not yet reported Wroclaw Medical University 47 participants Est. completion 2019-04-30 1 sitePrediabetesView official trial listing → -
Completed NCT NCT03398824
Pilot Study of Metformin for Patients With Fanconi Anemia
Not yet reported Boston Children's Hospital 15 participants Est. completion 2020-10-09 1 site Stand-aloneOther conditions: Fanconi AnemiaView official trial listing → -
Completed NCT NCT03416127
Effect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes Mellitus
Not yet reported University of Guadalajara 36 participants Est. completion 2019-12-20 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT03419624
The Potential of Dapagliflozin Plus Exenatide in Obese Insulin-resistant Patients
Not yet reported Universitätsklinikum Hamburg-Eppendorf 13 participants Est. completion 2019-08-05 4 sites Added to GLP-1Type 2 diabetes Other conditions: ObesityView official trial listing → -
Status unknown NCT NCT03421119
Comparing Efficacy and Safety of CinnaGen-liraglutide Versus Victoza® in Patients With Type II Diabetes
Not yet reported Cinnagen 300 participants Est. completion 2019-12-01 Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT03429543
Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM
Not yet reported Boehringer Ingelheim 175 participants Est. completion 2023-05-31 83 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03430856
Comparison of Insulin Tregopil (IN-105) With Insulin Aspart in Type 2 Diabetes Mellitus Patients
Not yet reported, Not yet reported Biocon Limited 143 participants Est. completion 2019-02-20 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03441750
Efficacy of Metformin in Preventing Diabetes in China
Not yet reported Chinese Association of Geriatric Research 1724 participants Est. completion 2021-06-30 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT03444584
Study of MEDI0382 in Combination With Dapagliflozin and Metformin in Overweight/Obese Participants With Type 2 Diabetes
Not yet reported MedImmune LLC 49 participants Est. completion 2018-12-06 8 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03445702
Metformin Gastrointestinal Intolerance: Measurement of Mitochondrial Complex I
Not yet reported St. Louis University 15 participants Est. completion 2020-10-27 1 site Stand-aloneType 2 diabetes Other conditions: Metformin Adverse ReactionView official trial listing → -
Terminated NCT NCT03451006
Effect of Metformin on Frailty in 12 Subjects
Not yet reported Mayo Clinic 7 participants Est. completion 2021-12-16 1 site Stand-aloneOther conditions: Aging, Inflammation, FrailtyView official trial listing → -
Completed NCT NCT03451734
Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients
Central South University 2000 participants Est. completion 2021-06-30 1 siteMetabolic syndrome Other conditions: SchizophreniaView official trial listing → -
Withdrawn NCT NCT03452267
Insulin Signaling in Skeletal Muscle
Not yet reported, Not yet reported Wayne State University Est. completion 2025-06 Stand-aloneOther conditions: Insulin SensitivityView official trial listing → -
Completed NCT NCT03452306
Bioequivalence Study of Metformin 750 mg Tablets XR Versus Glucophage® Long 750 mg Tablets XR In Normal Healthy Subjects Under Fasting and Fed Conditions
Not yet reported Geropharm 28 participants Est. completion 2017-07-22 1 site Stand-aloneOther conditions: BioequivalenceView official trial listing → -
Completed NCT NCT03458208
Bioequivalence Study of Metformin 1000 mg Tablets Immediate Release (IR) Versus Glucophage® 1000 mg Tablets IR In Healthy Subjects
Not yet reported Geropharm 18 participants Est. completion 2017-03-02 1 site Stand-aloneOther conditions: BioequivalenceView official trial listing → -
Completed NCT NCT03464045
Empa PASS on Urinary Tract Malignancies
Boehringer Ingelheim 344995 participants Est. completion 2024-03-11 3 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT03465345
Study of Metformin Plus Oligomeric Procyanidin Complex for Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients
Not yet reported Medical University of South Carolina Est. completion 2018-07-11 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT03467763
Trial of an Intervention to Improve Metformin Persistence and Adherence
Not yet reported Weill Medical College of Cornell University 13 participants Est. completion 2020-08-01 1 siteOther conditions: Metformin Adverse Reaction, ToleranceView official trial listing → -
Completed NCT NCT03467971
A Study to Assess the Food Effect on Bioavailability of Metformin/Gliclazide in Healthy Participants
Not yet reported Merck KGaA, Darmstadt, Germany 21 participants Est. completion 2018-04-22 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT03475524
USE THE SYSTEMIC METFORMIN IN MELASMA
Not yet reported Assiut University 60 participants Est. completion 2021-08 1 site Stand-aloneOther conditions: MelasmaView official trial listing → -
Terminated NCT NCT03477162
Metformin Pharmacology in Human Cancers: A Proof of Principle Study
Not yet reported Dartmouth-Hitchcock Medical Center 18 participants Est. completion 2021-11-30 1 site Stand-aloneOther conditions: Thoracic NeoplasmView official trial listing → -
Completed NCT NCT03479476
A Trial of Metformin in Individuals With Fragile X Syndrome
Not yet reported, Not yet reported University of California, Davis 120 participants Est. completion 2024-05-22 3 sitesOther conditions: Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome DisordersView official trial listing → -
Status unknown NCT NCT03486626
Endometrial Thickness and Subendometrial Vascularity in Anovulatory Polycystic Ovarian Syndrome Patients Treated by Metformin
Not yet reported Ain Shams Maternity Hospital 85 participants Est. completion 2018-10 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, AnovulatoryView official trial listing → -
Status unknown NCT NCT03489317
Gut Microbiomes in Patients With Metabolic Syndrome
Chinese University of Hong Kong 1000 participants Est. completion 2021-12 2 sitesMetabolic syndromeView official trial listing → -
Status unknown NCT NCT03489668
Androgen Responses to hCG and Ovarian Morphology in PCOS
Not yet reported Poznan University of Medical Sciences 100 participants Est. completion 2020-03-31 1 siteOther conditions: PCOSView official trial listing → -
Withdrawn NCT NCT03490019
Treatment of Bardet-Biedl-Syndrome With Metformin for Evaluation of a Possible Visual Improvement
Not yet reported University Hospital Tuebingen Est. completion 2020-08 Stand-aloneOther conditions: Bardet-Biedl Syndrome, Visual ImpairmentView official trial listing → -
Completed NCT NCT03491241
Inflammatory Axis and Sirtuins' in Overweight Pre-diabetics Patients
Not yet reported University of Campania Luigi Vanvitelli 60 participants Est. completion 2018-01-01 1 sitePrediabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT03495102
A Study of the Efficacy and Safety of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 1842 participants Est. completion 2019-10-10 208 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03499704
A Study to Evaluate the Effect of add-on Pioglitazone or Dapagliflozin in Participants With Type 2 Diabetes Mellitus Inadequately Controlled by DPP-4 Inhibitor and Metformin Therapy
Not yet reported Celltrion Pharm, Inc. 133 participants Est. completion 2024-01-16 15 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03503942
The Pre-Diabetes Interventions and Continued Tracking to Ease-out Diabetes (Pre-DICTED) Program
Not yet reported Singapore General Hospital 751 participants Est. completion 2024-04-15 1 site Stand-alonePrediabetesView official trial listing → -
Status unknown NCT NCT03507413
Metformin Therapy in Non-diabetic AAA Patients
Not yet reported, Not yet reported Medical University of Vienna 170 participants Est. completion 2024-05-01 1 siteOther conditions: Abdominal Aortic AneurysmView official trial listing → -
Completed NCT NCT03510390
Metformin in Head and Neck Squamous Cell Carcinoma: Effect on Tissue Oxygenation
Not yet reported Insel Gruppe AG, University Hospital Bern 17 participants Est. completion 2021-11-15 1 site Stand-aloneOther conditions: Head and Neck Cancer, Oral Cavity Squamous Cell CarcinomaView official trial listing → -
Status unknown NCT NCT03513874
Metformin Plus Insulin on Non-obese Autoimmune Diabetes
Not yet reported Second Xiangya Hospital of Central South University 15 participants Est. completion 2021-04-01 1 site Stand-aloneOther conditions: Type 1 Diabetes Mellitus, Autoimmune DiabetesView official trial listing → -
Completed NCT NCT03514108
DANHEART (H-HeFT and Met-HeFT)
Not yet reported Henrik Wiggers 1100 participants Est. completion 2025-12-31 26 sitesHeart failure Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT03525028
A Clinical Trial of Metformin to Decrease Glucocorticoids Side Effects in Patients With Autoimmune Uveitis
Not yet reported Tianjin Medical University 138 participants Est. completion 2023-01-01 1 site Stand-aloneOther conditions: Uveitis, Metformin, GlucocorticoidView official trial listing → -
Completed NCT NCT03529123
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes (LixiLan-India)
Not yet reported Sanofi 247 participants Est. completion 2019-11-25 13 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT03538704
Effect of Fertility-sparing Therapy of Early Endometrial Cancer
Not yet reported Peking University People's Hospital 80 participants Est. completion 2020-12-31 1 site Stand-aloneOther conditions: Endometrial Cancer, FertilityView official trial listing → -
Completed NCT NCT03546062
Diabetes and Lipid Accumulationand Heart Transplant
University of Campania Luigi Vanvitelli 177 participants Est. completion 2018-05-01 2 sitesHeart failure Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT03552991
Effects of Dietary Fiber on Glucose Control in Subjects With Type 2 Diabetes Mellitus
Not yet reported Samsung Medical Center 14 participants Est. completion 2018-05-31Type 2 diabetesView official trial listing → -
Completed NCT NCT03555565
Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"
Takeda 1026 participants Est. completion 2019-10-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03558867
Personalised Medicine in Pre-diabetes and Early Type 2 Diabetes
Not yet reported Garvan Institute of Medical Research 138 participants Est. completion 2024-07-23 1 siteType 2 diabetes Other conditions: Pre DiabetesView official trial listing → -
Completed NCT NCT03566225
Pioglitazone Versus Metformin as First Treatment in Infertile Women With Polycystic Ovary Syndrome
Not yet reported Ain Shams University 400 participants Est. completion 2021-03-30 1 siteOther conditions: PioglitazoneView official trial listing → -
Completed NCT NCT03566810
Glucophage Extended Release (GXR) China Bioequivalence Study (Nantong - Darmstadt)
Not yet reported Merck KGaA, Darmstadt, Germany 54 participants Est. completion 2018-11-28 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT03570632
Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus
Not yet reported Maisa N. Feghali, MD 24 participants Est. completion 2026-05-31 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1, Pregnancy in DiabetesView official trial listing → -
Withdrawn NCT NCT03577184
Evaluating the Glycemic Control wIth Vildagliptin and Metformin Combination Therapy.
Clinision Est. completion 2019-03Type 2 diabetesView official trial listing → -
Completed NCT NCT03583385
Glucophage® Extended Release (XR) 750 Milligram (mg) Indonesia Bioequivalence (BE) Study
Not yet reported Merck KGaA, Darmstadt, Germany 48 participants Est. completion 2018-10-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT03585777
Compare Serum Klotho Levels in Patients on Oral Antidiabetic Treatment
Fayoum University 90 participants Est. completion 2019-03 1 siteOther conditions: Compare Serum Level of Klotho in Patients on Oral Antidiabetic TreatmentView official trial listing → -
Status unknown NCT NCT03590262
Effect of Metformin as add-on Therapy on Glycemic Control and Other Outcomes in Type 1 Diabetes
Not yet reported Shenzhen People's Hospital 20 participants Est. completion 2019-09-30 1 site Stand-aloneOther conditions: Type 1 Diabetes Mellitus, MetforminView official trial listing → -
Completed NCT NCT03593135
Effect of Apple Cider Vinegar in Type 2 Diabetics
Not yet reported Sheikh Zayed Federal Postgraduate Medical Institute 126 participants Est. completion 2017-11-14 1 site Stand-aloneOther conditions: Randomized Controlled Trial, Diabetes MellitusView official trial listing → -
Completed NCT NCT03593538
Effects of Metformin During Nicotine Withdrawal
Not yet reported University of Pennsylvania 80 participants Est. completion 2020-03-13 1 site Stand-aloneOther conditions: Smoking, HIV-1-infectionView official trial listing → -
Completed NCT NCT03593707
Drug-Drug Interaction Study to Evaluate the Effect of PF-06865571 on Metformin Pharmacokinetics
Not yet reported Pfizer 18 participants Est. completion 2019-02-13 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT03596450
Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial
Not yet reported Novo Nordisk A/S 1278 participants Est. completion 2023-06-09 181 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT03600363
A Clinical Trial of Metformin in the Maintenance of Non-Hodgkin's Lymphoma Patients
Not yet reported Ruijin Hospital 250 participants Est. completion 2021-12 1 site Stand-aloneOther conditions: Lymphoma, Large B-Cell, Diffuse, Stage III Follicular LymphomaView official trial listing → -
Terminated NCT NCT03603080
Efficacy of Pharmacotherapy to Enhance Weight Loss Following Sleeve Gastrectomy
Not yet reported Hartford Hospital 12 participants Est. completion 2022-09-01 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT03603912
Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)
Not yet reported Mina Chung, MD 175 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Atrial FibrillationView official trial listing → -
Completed NCT NCT03604419
Dose-finding of PB-119 Administered Subcutaneously Once Weekly Versus Placebo in Subjects With Type 2 Diabetes
Not yet reported PegBio Co., Ltd. 214 participants Est. completion 2019-07-23 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03606694
Effect of Dihydromirycetin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes Mellitus
Not yet reported University of Guadalajara 24 participants Est. completion 2023-12-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT03608358
Safety and Efficacy of Dapagliflozin in Asian T2DM Subjects With Inadequate Glycemic Control on Metformin/Saxagliptin
Not yet reported AstraZeneca 41 participants Est. completion 2020-08-04 4 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03610412
Cinnamomum Cassia Effect on IGF1 and Metabolic Control in Patients With DM2 Without Glycemic Control Metformin Treated
Not yet reported Coordinación de Investigación en Salud, Mexico 28 participants Est. completion 2021-08-18 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03617458
Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension
Not yet reported Vanderbilt University Medical Center 73 participants Est. completion 2025-08-19 1 siteOther conditions: Pulmonary Artery HypertensionView official trial listing → -
Completed NCT NCT03618472
Comparison of the Effectiveness Metformin for Deceasing Proliferative Marker in Endometrial Cancer Cells
Not yet reported Department of Medical Services Ministry of Public Health of Thailand 50 participants Est. completion 2020-01-30 1 site Stand-aloneOther conditions: Metformin, CA EndometriumView official trial listing → -
Completed NCT NCT03618654
Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 38 participants Est. completion 2022-12-07 1 site Stand-aloneOther conditions: Head and Neck Squamous Cell Carcinoma, Oral Cavity Squamous Cell Carcinoma, Oropharyngeal Squamous Cell CarcinomaView official trial listing → -
Status unknown NCT NCT03627039
Metformin And Cardiovascular Effectiveness vs SGLT2 (MACES)
Brigham and Women's Hospital 20000 participants Est. completion 2020-08-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03629054
This Study in Healthy People Tests Whether Taking a Low Strength of Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2018-11-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03629340
Metformin for Pulmonary Hypertension HFpEF
Not yet reported University of California, San Francisco 33 participants Est. completion 2026-02-27 2 sites Stand-aloneHeart failure Other conditions: Pulmonary HypertensionView official trial listing → -
Status unknown NCT NCT03629639
Metformin for Treatment of Psoriasis Combined With Disorders of Glucose and Lipid Metabolism
Not yet reported Central South University 80 participants Est. completion 2020-12-01 Stand-aloneOther conditions: Psoriasis Vulgaris With Metabolic DisordersView official trial listing → -
Status unknown NCT NCT03639545
The Effects of Empagliflozin on Arterial Wall Characteristics
Not yet reported University Medical Centre Ljubljana 120 participants Est. completion 2019-01-30 1 siteOther conditions: Vascular Stiffness, Hypoglycemic Agents, Diabetes Complications, Diabetes Mellitus, Type 1View official trial listing → -
Withdrawn NCT NCT03640221
Ertugliflozin Versus Hydrochlorothiazide in Reducing Sympathetic Neural Overactivity in Patients With Hypertension and Recently-diagnosed Type 2 Diabetes.
Not yet reported Cedars-Sinai Medical Center Est. completion 2020-08-31 1 siteType 2 diabetes Other conditions: HypertensionView official trial listing → -
Completed NCT NCT03651895
Metformin to Reduce Airway Glucose in COPD Patients
Not yet reported Imperial College London 14 participants Est. completion 2023-06-01 1 siteOther conditions: Chronic Obstructive Pulmonary DiseaseView official trial listing → -
Completed NCT NCT03655301
Effect of Copanlisib on Metformin Pharmacokinetics and Pharmacodynamics
Not yet reported Bayer 13 participants Est. completion 2019-02-12 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT03655535
Multicenter Study to Evaluate the Effect of BTI320 on Glycemic Control in Type 2 Diabetes
Not yet reported Boston Therapeutics 66 participants Est. completion 2019-08-30 4 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03659461
Glucagon-like Peptide-1 Levels, Insulin Resistance and Insulin Sensitivity Index in Type 2 Diabetes Mellitus
Not yet reported National University of Malaysia 174 participants Est. completion 2020-01-31 1 site Stand-aloneType 2 diabetesPrediabetesView official trial listing → -
Completed NCT NCT03670043
Tolerance & Responsiveness Improvement for Metformin (TRIM)
Not yet reported West Side Institute for Science and Education 29 participants Est. completion 2021-08-15 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03674385
Efficacy of Vit E in PCOS Resistant to Clomiphene Citrate
Not yet reported Ain Shams University 60 participants Est. completion 2019-03-30 1 site Stand-aloneOther conditions: Clomiphene Citrate Resistant Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT03681197
Metformin Use and Clinical Pregnancy Rate in Women With Unexplained Infertility
Not yet reported Elham Raafat 170 participants Est. completion 2019-05 1 siteOther conditions: InfertilityView official trial listing → -
Terminated NCT NCT03684642
Efficacy and Safety of Efpeglenatide Versus Dulaglutide in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin
Not yet reported Sanofi 908 participants Est. completion 2020-11-17 45 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03684707
Cancer Chemoprevention by Metformin Hydrochloride Compared to Placebo in Oral Potentially Malignant Lesions
Not yet reported Ain Shams University 30 participants Est. completion 2019-09-15 1 siteOther conditions: Oral CancerView official trial listing → -
Status unknown NCT NCT03685357
Correlation Between Idiopathic Parkinson's Disease and Diabetes Mellitus
Ain Shams University 120 participants Est. completion 2020-01 1 siteOther conditions: ObservationView official trial listing → -
Status unknown NCT NCT03685409
Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions
Not yet reported Cairo University 62 participants Est. completion 2020-09-30 1 siteOther conditions: Oral CancerView official trial listing → -
Withdrawn NCT NCT03686657
Evaluation of Superiority of Valsartan+Celecoxib+Metformin Over Metformin Alone in Type 2 Diabetes Patients
Not yet reported, Not yet reported ARKAY Therapeutics Est. completion 2031-01-31 1 site Stand-aloneType 2 diabetes Other conditions: High Blood Pressure, Arthritis, ObesityView official trial listing → -
Completed NCT NCT03686722
Effect of Co-administration of Metformin and Daclatasvir on the Pharmacokinetis and Pharmacodynamics of Metformin
Not yet reported Mohamed Raslan 20 participants Est. completion 2017-12-06 1 site Stand-aloneType 2 diabetes Other conditions: Hepatitis C, Drug InteractionsView official trial listing → -
Completed NCT NCT03689374
A Research Study to Compare Semaglutide to Insulin Aspart, When Taken Together With Metformin and Insulin Glargine, in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 2274 participants Est. completion 2021-02-22 210 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT03690778
The PK Characteristics of the Co-administration of Metformin SR and Rosuvastatin and JLP-1310 in Healthy Male Volunteers.
Not yet reported Jeil Pharmaceutical Co., Ltd. 42 participants Est. completion 2019-02-01 1 site Stand-aloneOther conditions: Diabetes, HyperlipidemiasView official trial listing → -
Completed NCT NCT03693560
Effect of Adding Vildagliptin vs Glimepiride to Metformin on Inflammation's Markers in Type-2 Diabetic Patients With CAD
Not yet reported Damanhour University 80 participants Est. completion 2019-10-10 1 site Stand-aloneCardiovascular diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT03700801
Study of Efficacy, Weight Control, and Safety in Newly-diagnosed Type 2 Diabetes With Different Antidiabetic Therapy
Not yet reported Zhujiang Hospital 130 participants Est. completion 2019-12-20 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03708549
Comparison of Berberine and Metformin for the Treatment for MS in Schizophrenia Patients
Not yet reported Tianjin Anding Hospital 100 participants Est. completion 2023-12-01 1 site Stand-aloneMetabolic syndrome Other conditions: Schizophrenia, Berberine, MetforminView official trial listing → -
Status unknown NCT NCT03709147
Metformin Plus/Minus Fasting Mimicking Diet to Target the Metabolic Vulnerabilities of LKB1-inactive Lung Adenocarcinoma
Not yet reported Marina Garassino 64 participants Est. completion 2023-09-10 1 site Stand-aloneOther conditions: Advanced LKB1-inactive Lung AdenocarcinomaView official trial listing → -
Completed NCT NCT03710343
Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study
Not yet reported Holland Bloorview Kids Rehabilitation Hospital 3 participants Est. completion 2025-04-24 2 sites Stand-aloneOther conditions: Cerebral PalsyView official trial listing → -
Status unknown NCT NCT03710460
Effect of Dapagliflozin/Metformin XR vs Monotherapies on Anthropometric Indicators in Obesity
Not yet reported University of Guadalajara 33 participants Est. completion 2023-12-30 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT03711682
Reducing Plasma Glucose Effect of Cinnamon in Type 2 Diabetic Patients in the Municipality of Comasagua
Not yet reported, Not yet reported Universidad Dr. José Matías Delgado 30 participants Est. completion 2018-05-23 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03713801
Impact of Metformin on Immunity
Not yet reported The University of Texas Health Science Center at San Antonio 18 participants Est. completion 2024-07-16 1 site Stand-aloneOther conditions: Aging, Vaccine Response ImpairedView official trial listing → -
Completed NCT NCT03714594
Effects of Dapagliflozin+Saxagliptin in Addition to Metformin v/s Saxagliptin or Dapagliflozin in Patients With DM2.
Not yet reported University of Pisa 48 participants Est. completion 2022-08-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03717194
Effect of Ertugliflozin on Cardiac Function in Diabetes
Not yet reported Soo Lim 102 participants Est. completion 2023-04-30 1 site Stand-aloneType 2 diabetesHeart failureView official trial listing → -
Status unknown NCT NCT03717701
Metformin and Esomeprazole in Treatment of Early Onset Preeclampsia
Not yet reported Aswan University Hospital 120 participants Est. completion 2021-01-01 1 site Stand-aloneOther conditions: Pre-EclampsiaView official trial listing → -
Status unknown NCT NCT03718715
The Interaction Between Metformin and Microbiota - the MEMO Study.
Umeå University 600 participants Est. completion 2022-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03722290
Metformin in Children and Adults With Fragile X Syndrome
Not yet reported Université de Sherbrooke 15 participants Est. completion 2020-11-01 1 site Stand-aloneOther conditions: Fragile X SyndromeView official trial listing → -
Completed NCT NCT03733132
Metformin Effect on Brain Function in Insulin Resistant Elderly People
Not yet reported Mayo Clinic 40 participants Est. completion 2023-04-05 1 siteOther conditions: Insulin Resistance, Obesity, Obesity, AbdominalView official trial listing → -
Completed NCT NCT03737240
IDegLira HIGH Trial
Not yet reported Emory University 145 participants Est. completion 2022-07-08 2 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT03746106
The Effect of SLC19A3 Inhibition on the Pharmacokinetics of Thiamine
Not yet reported University of California, San Francisco 7 participants Est. completion 2023-08-10 1 site Stand-aloneOther conditions: Vitamin B1 Deficiency, Thiamine DeficiencyView official trial listing → -
Completed NCT NCT03748810
Head-to-head Comparison of Empagliflozin and Dapagliflozin
Chungbuk National University Hospital 600 participants Est. completion 2022-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03751657
A Research Study to Compare Insulin 287 Once a Week to Insulin Glargine (100 Units/mL) Once a Day in People With Type 2 Diabetes.
Not yet reported Novo Nordisk A/S 247 participants Est. completion 2020-01-17 49 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03756623
Effect of Metformin and Probiotics on Gut Microbiome in Healthy Subjects
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 90 participants Est. completion 2019-06-30 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT03757910
Brain Imaging in the Diabetes Prevention Program Outcomes Study
Not yet reported José A. Luchsinger 5 participants Est. completion 2023-01-31 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT03757923
Comparison of Metformin and Pioglitazone in Regulating Menstrual Irregularities and Hyperandrogenism
Not yet reported, Not yet reported Dow University of Health Sciences 110 participants Est. completion 2019-01 1 site Stand-aloneOther conditions: Menstrual Irregularities, HyperandrogenismView official trial listing → -
Terminated NCT NCT03761134
Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Metformin With or Without Sulfonylurea
Not yet reported Sanofi 377 participants Est. completion 2020-04-29 40 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03764605
Metformin vs Tolvaptan for Treatment of Autosomal Dominant Polycystic Kidney Disease
Not yet reported Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari 150 participants Est. completion 2022-01-30 2 sites Stand-aloneOther conditions: ADPKDView official trial listing → -
Completed NCT NCT03765359
Metformin Use to Improve Pregnancy Outcome in Women With Type 1 Diabetes.
Not yet reported Tampere University Hospital 101 participants Est. completion 2022-12-19 5 sitesOther conditions: Diabetic Pregnancy, Insulin Resistance, Type1diabetesView official trial listing → -
Completed NCT NCT03766256
Shared Decision Making in Diabetes Prevention for Women With a History of GDM
Not yet reported University of California, Los Angeles 33 participants Est. completion 2019-12-28 20 sites Stand-aloneOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT03766308
The Clinical Study of the Effect of Highland Barley Diet on Blood Glucose in Patients With Type 2 Diabetes Mellitus
Not yet reported Xuefeng Yu 40 participants Est. completion 2020-12-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03770052
Glucose-Lowering Effects and Safety of Adding 0.25 or 0.5 mg Duvie
Not yet reported Pusan National University Hospital 159 participants Est. completion 2021-09-13 1 site Stand-aloneType 2 diabetes Other conditions: Inadequate Glucose ControlView official trial listing → -
Terminated NCT NCT03770728
Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin Alone or in Combination With Sulfonylurea
Not yet reported Sanofi 312 participants Est. completion 2020-12-27 48 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03772262
Assessing Goldenseal-drug Interactions Using a Probe Drug Cocktail Approach
Not yet reported Washington State University 16 participants Est. completion 2019-03-31 1 site Stand-aloneOther conditions: Interaction Drug FoodView official trial listing → -
Completed NCT NCT03772964
Effects of Metformin in a Non-Diabetic Patient Population
Not yet reported, Not yet reported Brian Zuckerbraun 32 participants Est. completion 2020-03-31 1 site Stand-aloneOther conditions: Inflammatory ResponseView official trial listing → -
Status unknown NCT NCT03774108
Metformin and Systemic Inflammation in HIV
Not yet reported Hospital Civil de Guadalajara 40 participants Est. completion 2020-01-08 1 site Stand-alonePrediabetes Other conditions: HIV-1-infectionView official trial listing → -
Completed NCT NCT03787017
A Study to Compare MP-513 20mg & Metformin XR 1000mg FDC With Coadministration of the Two Separate Drugs
Not yet reported Handok Inc. 36 participants Est. completion 2014-09 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT03787043
A Study to Evaluate the Effect of Food on Fixed-Dose Combination of MP-513 10 mg and Metformin XR 750 mg
Not yet reported Handok Inc. 30 participants Est. completion 2014-06 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT03792984
The Effect of Calcium and Vitamin D Supplements on Metabolic and Hormonal Disturbances in Polycystic Ovary Syndrome Patients
Not yet reported Damascus University 40 participants Est. completion 2017-12-30 2 sites Stand-aloneOther conditions: Polycystic Ovary Syndrome, Vitamin D Deficiency/InsufficiencyView official trial listing → -
Completed NCT NCT03794336
Efficacy and Safety of Alogliptin vs. Acarbose in Chinese Type 2 Diabetes Mellitus (T2DM) Patients With High CV Risk or CHD Treated With Aspirin and Inadequately Controlled With Metformin Monotherapy or Drug Naive
Not yet reported Sanofi 1293 participants Est. completion 2020-12-14 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03796182
Study of PF 04965842 Effect on MATE1/2K Activity in Healthy Participants
Not yet reported Pfizer 12 participants Est. completion 2019-03-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03796975
Efficacy of Pioglitazone Hydrochloride and Metformin Hydrochloride Tablets on the Patients With Newly Diagnosed Type 2 Diabetes Mellitus Combined With Non-alcoholic Fatty Liver Disease
Not yet reported Xijing Hospital 120 participants Est. completion 2019-11-20 1 site Stand-aloneType 2 diabetes Other conditions: Non-alcoholic Fatty Liver Disease, EfficacyView official trial listing → -
Completed NCT NCT03798054
Evaluation of Insulin Glargine/Lixisenatide Fixed Ratio Combination in Patients With Type 2 Diabetes Insufficiently Controlled With Oral Antidiabetic Drug(s)
Not yet reported Sanofi 878 participants Est. completion 2021-03-01 79 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT03798080
Comparison of the Efficacy and Safety of Insulin Glargine/Lixisenatide Fixed Ratio Combination to Insulin Glargine in Patients With Type 2 Diabetes Insufficiently Controlled on Basal Insulin
Not yet reported Sanofi 426 participants Est. completion 2020-12-01 45 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT03800602
Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancer
Not yet reported Emory University 29 participants Est. completion 2021-09-04 3 sites Stand-aloneObstructive sleep apnea Other conditions: Colorectal Adenocarcinoma, Refractory Colorectal Carcinoma, Stage IV Colorectal Cancer, Stage IVA Colorectal Cancer, Stage IVB Colorectal Cancer, Stage IVC Colorectal Cancer, Colorectal Cancer MetastaticView official trial listing → -
Completed NCT NCT03809260
A Clinical Trial for Analysis of Intestinal Microbiome Affecting PK, PD, and Safety of Metformin
Not yet reported Seoul National University Hospital 20 participants Est. completion 2019-02-28 1 site Stand-aloneOther conditions: Human MicrobiomeView official trial listing → -
Withdrawn NCT NCT03813316
Approaches To Therapy Escalation In T2D
Not yet reported LMC Diabetes & Endocrinology Ltd. Est. completion 2019-09-18 Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT03816488
Oral Peri-operative TIming of Metformin (or) Salsalate to Improve Non-cardiac Surgery Glucose Control
Not yet reported McMaster University Est. completion 2024-12-01 Stand-aloneType 2 diabetes Other conditions: Hyperglycemia, Perioperative/Postoperative Complications, Salsalate to Improve Non-cardiac Surgery Glucose ControlView official trial listing → -
Completed NCT NCT03819127
Vildagliptin in Older Adults With Diabetes and Mild Cognitive Impairment
Not yet reported University of Catania 60 participants Est. completion 2016-09 Stand-aloneOther conditions: Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT03819790
The Effect of Soliqua on Glucose Variability in Type 2 Patients Among South Asians
Not yet reported LMC Diabetes & Endocrinology Ltd. 119 participants Est. completion 2019-11-19 3 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT03824002
Dulaglutide in Diabetic Patients, Relationship Between Arterial Stiffness, Endothelial Function, Clinical and Laboratory Variables
Not yet reported University of Palermo 92 participants Est. completion 2018-04-20 1 site Added to GLP-1Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT03826602
A Drug-Drug Interaction Study in Healthy Volunteers of the Effects of Tucatinib on Metformin
Not yet reported Seagen Inc. 18 participants Est. completion 2019-03-15 1 site Stand-aloneOther conditions: Drug-drug InteractionView official trial listing → -
Completed NCT NCT03826641
A Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HCP1801 in Healthy Subjects
Not yet reported Hanmi Pharmaceutical Company Limited 85 participants Est. completion 2019-04-16 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03829020
Metformin, Nelfinavir, and Bortezomib in Treating Patients With Relapsed and/or Refractory Multiple Myeloma
Not yet reported Mayo Clinic 9 participants Est. completion 2023-11-24 2 sites Stand-aloneOther conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell MyelomaView official trial listing → -
Status unknown NCT NCT03831464
Metformin as RenoProtector of Progressive Kidney Disease
Not yet reported Universiteit Antwerpen 290 participants Est. completion 2024-12-31 19 sites Stand-aloneChronic kidney diseaseView official trial listing → -
Status unknown NCT NCT03833466
Metformin in Combined With Cisplatin Plus Paclitaxel With Advanced Esophageal Squamous Cell Carcinoma (ECMTPneo)
Not yet reported Peking University 15 participants Est. completion 2020-06-20 1 site Stand-aloneOther conditions: Esophageal Squamous Cell CarcinomaView official trial listing → -
Completed NCT NCT03841591
Maternal Weight Gain in Gestational Diabetes Controlled by Metformin Versus Insulin
Not yet reported Ain Shams University 124 participants Est. completion 2019-01-15 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT03842267
A Study to Evaluate the Efficacy and Safety of Gemigliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Dapagliflozin and Metformin (SOLUTION Study)
Not yet reported LG Chem 315 participants Est. completion 2022-11-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03845153
Metformin Effect on Fracture Healing in Post-Menopausal Women
Not yet reported Damanhour University 40 participants Est. completion 2021-01-01 1 siteOther conditions: Bone FractureView official trial listing → -
Status unknown NCT NCT03848533
Effect of Melatonin and Metformin on Glycemic Control Genotoxicity and Cytotoxicity Markers in Patients With Prediabetes
Not yet reported University of Guadalajara 42 participants Est. completion 2021-12 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT03850886
Nicotinamide in Non-Alcoholic Fatty Liver Disease Patients
Not yet reported Ain Shams University 61 participants Est. completion 2019-08-07 1 site Stand-aloneOther conditions: Non Alcoholic Fatty Liver DiseaseView official trial listing → -
Status unknown NCT NCT03851432
Janagliflozin Treat Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled With Metformin
Not yet reported Sihuan Pharmaceutical Holdings Group Ltd. 390 participants Est. completion 2021-12-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT03856632
Liraglutide Effect in Atrial Fibrillation
Not yet reported University of Miami 60 participants Est. completion 2026-12-31 1 site Added to GLP-1Other conditions: Atrial FibrillationView official trial listing → -
Terminated NCT NCT03861767
REMAP Trial for Optimizing Surgical Outcomes at UPMC
Not yet reported Matthew Neal MD 302 participants Est. completion 2022-09-23 1 site Stand-aloneOther conditions: AgingView official trial listing → -
Completed NCT NCT03862716
Remission Evaluation of a Metabolic Intervention for Type 2 Diabetes With IDegLira
Not yet reported Population Health Research Institute 159 participants Est. completion 2023-07-31 8 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03862950
A Trial of Metformin in Individuals With Fragile X Syndrome (Met)
Not yet reported University of Alberta 125 participants Est. completion 2025-12-16 2 sitesOther conditions: Fragile X Syndrome, Fragile X Mental Retardation Syndrome, Mental Retardation, X-Linked, Genetic Diseases, X-Linked, Trinucleotide Repeat Expansion, Fra(X) Syndrome, Intellectual Disability, FXS, Neurobehavioral Manifestations, Sex Chromosome DisordersView official trial listing → -
Completed NCT NCT03862963
Lifestyle Intervention to Treat Diabetes in the Marshall Islands
Not yet reported University of Alabama at Birmingham 138 participants Est. completion 2008-07-31Type 2 diabetesView official trial listing → -
Status unknown NCT NCT03863405
Metformin Use in Rheumatoid Arthritis
Not yet reported Ain Shams University 60 participants Est. completion 2020-01-09 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT03864705
Compliance of Diabetic Patients Treated With Metformin
Institute for Clinical and Experimental Medicine 400 participants Est. completion 2021-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03871621
Left Ventricular Functional Changes of Uncontrolled Diabetes by Dapagliflozin Treatment Trial
Not yet reported Mackay Memorial Hospital 76 participants Est. completion 2022-08-31 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03874000
Sintilimab Combined With Metformin in First-Line Chemotherapy Refractory Advanced NSCLC Patients
Not yet reported Tianjin Medical University Cancer Institute and Hospital 43 participants Est. completion 2022-06-05 1 site Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Status unknown NCT NCT03877406
Effect of Empagliflozin on Body Composition and Ketones
Not yet reported Seoul National University Bundang Hospital 200 participants Est. completion 2023-12-31 1 siteOther conditions: Diabetes Mellitus, Fat; Intolerance, PancreasView official trial listing → -
Status unknown NCT NCT03877783
DEMAND - Multifactorial Study to Reduce Dementia in People With Type 2 Diabetes
Not yet reported Umeå University 10 participants Est. completion 2023-06-30 1 site Stand-aloneType 2 diabetes Other conditions: Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT03880825
Drug Interaction Study of Levoketoconazole and Metformin
Not yet reported Cortendo AB 32 participants Est. completion 2019-05-03 1 siteOther conditions: Healthy SubjectsView official trial listing → -
Active, not recruiting NCT NCT03889795
Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors
Not yet reported Danae Hamouda, MD 15 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Advanced Pancreatic Cancer, Advanced Solid TumorView official trial listing → -
Completed NCT NCT03893422
Placebo-Controlled Clinical Nutrition Study of the Safety and Metabolic Effects of Two Medical Foods in Type 2 Diabetes
Not yet reported Pendulum Therapeutics 76 participants Est. completion 2018-09-14 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03898037
Effect of Lifestyle and/or Metformin Intervention on Pregnancy Outcome, A Pilot Randomized Controlled Trial
Not yet reported Reproductive & Genetic Hospital of CITIC-Xiangya 80 participants Est. completion 2021-06-30 1 site Stand-aloneOther conditions: Infertility, Female, Obesity, Insulin ResistanceView official trial listing → -
Withdrawn NCT NCT03905941
Relative Desirability of Metformin vs. Birth Control Pill in Treating PCOS in Women of Later Reproductive Age
Not yet reported University of Virginia Est. completion 2024-11-25 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Terminated NCT NCT03907202
A Clinical Study to Evaluate the Safety, Tolerability, PK, PD, and Efficacy of KBP-089 in Patients With T2DM
Not yet reported KeyBioscience AG 25 participants Est. completion 2019-12-03 1 siteOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT03907423
Rosuvastatin on Diabetic Patients Treated With Glimepiride/Metformin
Not yet reported Rehab Werida 70 participants Est. completion 2021-01-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03916263
Low Starch Dietary Education Program vs. Traditional Treatment for PCOS
Not yet reported Texas Tech University Health Sciences Center 71 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: PCOS, Diet Modification, Metabolism, Nutrition DisordersView official trial listing → -
Status unknown NCT NCT03917758
Antidiuretic Function Before and During Treatment With SGLT2 Inhibitors
Not yet reported University of Turin, Italy 30 participants Est. completion 2020-10-30 1 site Stand-aloneType 2 diabetes Other conditions: Arterial Hypertension, Body Weight ChangesView official trial listing → -
Completed NCT NCT03918148
Gliflozins and Cardiovascular Risk Factors in Type 2 Diabetes (GIOIA)
University of Campania Luigi Vanvitelli 1150 participants Est. completion 2023-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03921242
Comparative Effectiveness of Metformin for Type 2 Diabetes With Chronic Kidney Disease
Weill Medical College of Cornell University 4888 participants Est. completion 2023-08-01 2 sitesType 2 diabetes Other conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT03922750
A Research Study in People With Type 2 Diabetes to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine
Not yet reported Novo Nordisk A/S 154 participants Est. completion 2020-01-27 38 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03927170
Pharmacokinetic Characteristics of GLH1SM Extended Release Tablets in Healthy Volunteers(Fed)
Not yet reported GL Pharm Tech Corporation 25 participants Est. completion 2019-10-23 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03928340
Effect of Adding Metformin to Insulin Therapy on Pregnancy Outcomes in Women With Uncontrolled Type I Diabetes.
Not yet reported Kasr El Aini Hospital 80 participants Est. completion 2020-03-29 1 siteOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03934021
Gut Microbiota in Acute Stroke Patients
Chinese University of Hong Kong 120 participants Est. completion 2024-08-30 1 siteCardiovascular disease Other conditions: Microbiome, Atherosclerosis CerebralView official trial listing → -
Completed NCT NCT03945656
A Research Study of How Overdosing of a New Once Weekly Medicine NNC0148-0287 C (Insulin 287) Influences the Blood Sugar Level in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 43 participants Est. completion 2021-09-27 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03950505
To Evaluate the Effect of Nesinaact on Non-alcoholic Steatohepatitis Through MRI and Liver Fibroscan in Patients With Type 2 Diabetes
Not yet reported Yonsei University 60 participants Est. completion 2020-12 1 siteType 2 diabetes Other conditions: Non-alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT03951805
A Research Study to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine in People With Type 2 Diabetes Who Have Not Used Insulin Before
Not yet reported Novo Nordisk A/S 205 participants Est. completion 2020-01-17 43 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03956290
Time Restricted EATing (TREAT) Pilot Study
Not yet reported Columbia University 64 participants Est. completion 2021-01-11 1 siteOther conditions: Overweight and Obesity, Pre DiabetesView official trial listing → -
Completed NCT NCT03958591
Impact of Short-term Intensive De-escalation Therapy on Long-term Regimen Simplification
Not yet reported Yanbing Li 276 participants Est. completion 2026-03-31 1 site Stand-aloneOther conditions: Diabetes type2View official trial listing → -
Completed NCT NCT03960333
Immunometabolism in Pediatric Obesity
Arkansas Children's Hospital Research Institute 82 participants Est. completion 2024-06-30 1 siteType 2 diabetes Other conditions: Obesity, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT03961659
Effects of Liraglutid, Dapagliflozin and Acarbose on the Cognitive Function, Olfactory Function, and Odor-induced Brain Activation in Overweight/Obese T2DM Patients Controlled Inadequately With Metformin Monotherapy.
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 87 participants Est. completion 2021-02 1 siteType 2 diabetes Other conditions: Obesity, Cognitive ImpairmentView official trial listing → -
Completed NCT NCT03967496
Assessment of Immediate Postoperative Delirium (IPD) in Adult Patients: Incidence and Etiologic Factors
Sultan Qaboos University 402 participants Est. completion 2019-03-31 1 siteOther conditions: Delirium, Anesthesia; Adverse EffectView official trial listing → -
Completed NCT NCT03968224
Effectiveness of Dapagliflozin for Weight Loss
Not yet reported, Not yet reported Centro Medico Nacional Siglo XXI IMSS 160 participants Est. completion 2024-07-31 1 site Stand-alonePrediabetesType 2 diabetes Other conditions: Obesity, MorbidView official trial listing → -
Completed NCT NCT03969719
A Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus
Not yet reported Pfizer 164 participants Est. completion 2021-03-30 106 sitesOther conditions: Non-alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT03970434
Drug Concentration of Metformin According to Sampling Method
Not yet reported Chonbuk National University Hospital 20 participants Est. completion 2019-06-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT03972982
Effects of Structured Simplified Short-term Intensive Insulin Therapy on Long-term Glycemic Remission
Not yet reported Sun Yat-sen University 330 participants Est. completion 2022-12-31 1 site Stand-aloneType 2 diabetes Other conditions: Simplified Short-term Intensive Insulin Therapy, Glycemic RemissionView official trial listing → -
Status unknown NCT NCT03974139
Impact of Metformin on Leptin Transport in Cerebrospinal Fluid of Obese Patients
Not yet reported Lille Catholic University 31 participants Est. completion 2024-09-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03980990
Metformin Continuation Versus Interruption Following Coronary Angiography: a Pilot Randomized Controlled Trial
Not yet reported University of Saskatchewan 500 participants Est. completion 2020-06-17 1 site Stand-aloneOther conditions: Acute Coronary Syndrome, Unstable Angina, Diabetes Mellitus, Metformin Adverse ReactionView official trial listing → -
Completed NCT NCT03981861
Metabolic and Neuro-Endocrine Effect of Treating PCOS in Adolescents
Not yet reported, Not yet reported Children's Mercy Hospital Kansas City 12 participants Est. completion 2019-06-05 1 site Stand-aloneOther conditions: PCOSView official trial listing → -
Completed NCT NCT03982238
Effects of Hypoglycemic Drugs on Testosterone Levels in Type 2 Diabetes Patients
Not yet reported Majianhua 74 participants Est. completion 2019-12-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03982381
SGLT2 Inhibitor or Metformin as Standard Treatment of Early Stage Type 2 Diabetes
Not yet reported Uppsala University 2067 participants Est. completion 2026-01-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03983551
Comparing the Renal Effect of Dipeptidyl-peptidase 4 Inhibitors and Sulfonylureas
Not yet reported Changhua Christian Hospital 101 participants Est. completion 2018-02-28 Stand-aloneType 2 diabetes Other conditions: ProteinuriaView official trial listing → -
Completed NCT NCT03987919
A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 1879 participants Est. completion 2021-02-15 127 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT03994744
Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLC
Not yet reported Hunan Cancer Hospital 68 participants Est. completion 2022-07-01 1 site Stand-aloneOther conditions: Small-cell Lung Cancer, Small Cell Lung Carcinoma, Small Cell Lung Cancer Recurrent, Small Cell Lung Cancer Extensive StageView official trial listing → -
Completed NCT NCT03996538
Vaccination Efficacy With Metformin in Older Adults
Not yet reported UConn Health 26 participants Est. completion 2020-02-04 1 site Stand-aloneOther conditions: Aging, Age-Related Immunodeficiency, Vaccine Response ImpairedView official trial listing → -
Status unknown NCT NCT04001725
Efficacy of metfOrmin in PrevenTIng Glucocorticoid-induced Diabetes in Patients With Brain Metastases
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 110 participants Est. completion 2022-03-31 1 site Stand-aloneOther conditions: Brain Metastases, Melanoma, Lung Cancer, Breast CancerView official trial listing → -
Completed NCT NCT04008186
A Clinical Drug-Drug Interaction (DDI) Study With Omaveloxolone
Not yet reported Biogen 61 participants Est. completion 2019-08-28 1 site Stand-aloneOther conditions: Healthy Adult SubjectsView official trial listing → -
Completed NCT NCT04009603
Comparison of Probiotics, Metformin & Their Combination Therapy in the Treatment of PCOS
Not yet reported Ziauddin University 78 participants Est. completion 2020-01-28 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04010942
Vitamin D for Polycystic Ovary Syndrome Clomiphene Resistant Women
Not yet reported Ain Shams University 120 participants Est. completion 2019-03-30 1 siteOther conditions: PCOS, Vitamin D DeficiencyView official trial listing → -
Completed NCT NCT04013581
Quadruple Oral Combination Therapy for Type 2 Diabetes Mellitus : Glycemic Control by Thiazolidinedione (TZD) or Sodium Glucose Co-transporter 2 (SGLT-2) Inhibitor as an add-on Therapy in Type 2 Diabetes Mellitus After Failure of an Oral Triple Antidiabetic Regimen
Not yet reported Yonsei University 121 participants Est. completion 2020-05-28 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04017221
Safety of Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors Among Patients With Type 2 Diabetes
Canadian Network for Observational Drug Effect Studies, CNODES 1249636 participants Est. completion 2019-12-01 1 siteType 2 diabetes Other conditions: Urosepsis, Diabetic Ketoacidosis, Lower Extremity AmputationView official trial listing → -
Completed NCT NCT04017832
A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1441 participants Est. completion 2021-10-27 93 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT04018105
Influence of Preprandial Metformin Administration on Carbohydrate Absorption
Not yet reported University Hospital, Lille 1 participants Est. completion 2025-04-05 Stand-alonePrediabetesType 2 diabetesView official trial listing → -
Status unknown NCT NCT04027023
Evaluation of the Impact of Intensive Short-Term Drug Therapy in Patients With Type 2 Diabetes Mellitus
Not yet reported Sciema UG 9 participants Est. completion 2021-05-31 2 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT04029272
Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients
Not yet reported Peking Union Medical College Hospital 80 participants Est. completion 2020-12-31 1 site Added to GLP-1Other conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04029480
Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)
Not yet reported Merck Sharp & Dohme LLC 166 participants Est. completion 2025-04-11 104 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04033107
High Dose Vitamin C Combined With Metformin in the Treatment of Malignant Tumors
Not yet reported Zhongnan Hospital 30 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Hepatocellular Cancer, Pancreatic Cancer, Gastric Cancer, Colorectal CancerView official trial listing → -
Completed NCT NCT04039503
A Study of Tirzepatide (LY3298176) Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine With or Without Metformin
Not yet reported Eli Lilly and Company 475 participants Est. completion 2021-01-13 48 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04043221
Long Term Metformin in Women With Polycystic Ovary Syndrome
University Medical Centre Ljubljana 180 participants Est. completion 2019-01-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Terminated NCT NCT04047537
Placebo-Controlled Clinical Nutrition Study of the Metabolic Effects of Food Product WBF-0011 in Type 2 Diabetes
Not yet reported Pendulum Therapeutics 41 participants Est. completion 2020-05-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04047940
A Study of LY900020 in Healthy Chinese Participants
Not yet reported Eli Lilly and Company 32 participants Est. completion 2020-02-18 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT04050098
Bioequivalence Study for Gemigliptin/Metformin 50/1000 mg and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.
Not yet reported LG Chem 24 participants Est. completion 2019-11-30Type 2 diabetesView official trial listing → -
Status unknown NCT NCT04053621
Co-administration of Thiamine Pyrophosphate and Metformin in Type 2 Diabetes
Not yet reported Laboratorios Manuell SA 92 participants Est. completion 2022-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04064073
Study to Evaluate Drug-Drug Interaction of DWP16001 in Combination With Metformin in Healthy Male Adults (Phase 1 Study)
Not yet reported Daewoong Pharmaceutical Co. LTD. 34 participants Est. completion 2019-11-20 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT04065581
Bioequivalence Study for Acarbose/Metformin FDC
Not yet reported Bayer 24 participants Est. completion 2020-03-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04068246
The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Rheumatoid Arthritis Patients
Not yet reported, Not yet reported Sadat City University 120 participants Est. completion 2021-02-28 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Status unknown NCT NCT04070794
Food-effect Bioavailability of Fixed Dose Combination Zemimet® SR Tab. 50/1000 mg Under Fed and Fasting Conditions
Not yet reported LG Chem 24 participants Est. completion 2019-12-30Type 2 diabetesView official trial listing → -
Completed NCT NCT04075110
Investigation the Safety and Efficacy of The Antileukotriene Agents, Montelukast, as Adjuvant Therapy in Obese Patients With Type 2 Diabetes Mellitus
Not yet reported Sadat City University 100 participants Est. completion 2023-04-10 1 site Stand-aloneOther conditions: Obesity; Endocrine; Diabetes Type 2View official trial listing → -
Completed NCT NCT04081857
A Study to Evaluate the Pharmacokinetics and Safety of HCP1704 in Healthy Subjects
Not yet reported Hanmi Pharmaceutical Company Limited 48 participants Est. completion 2019-08-05 1 site Stand-aloneOther conditions: Health, SubjectiveView official trial listing → -
Completed NCT NCT04088448
The Antidiabetic Metformin as a Novel Adjunct to Antidepressants in Major Depressive Disorder Patients
Not yet reported, Not yet reported Sadat City University 80 participants Est. completion 2020-06-01 1 site Stand-aloneOther conditions: Major Depressive DisorderView official trial listing → -
Completed NCT NCT04088461
Effect of Linagliptin + Metformin on Patients Who do Not Achieve Normoglucemia With Metformine
Not yet reported Universidad de Guanajuato 31 participants Est. completion 2018-09 1 site Stand-alonePrediabetes Other conditions: Prediabetic State, Insulin ResistanceView official trial listing → -
Active, not recruiting NCT NCT04088851
"Hepatic Substrate Flux Rates in Type 2 Diabetes"
Not yet reported German Diabetes Center 23 participants Est. completion 2025-12-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04089813
Effect of Metformin on Chronic Pain After Thoracic Surgery in Diabetic Patients
Xuzhou Medical University 200 participants Est. completion 2020-12-31 1 siteOther conditions: Postoperative Chronic PainView official trial listing → -
Completed NCT NCT04090580
Impact on Glycemic Variability in Newly Onset T2DM Patients Initiating Dapagliflozin Plus Metformin Versus Metformin Alone
Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 88 participants Est. completion 2021-03-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04093752
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes on Metformin With or Without Sulfonylurea (SURPASS-AP-Combo)
Not yet reported Eli Lilly and Company 917 participants Est. completion 2021-11-24 67 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04098666
Metformin in Alzheimer's Dementia Prevention
Not yet reported, Not yet reported Columbia University 326 participants Est. completion 2027-04-30 22 sites Stand-aloneOther conditions: Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT04113889
Effects of Triple Drug Cocktail Therapy on Metabolic, Endocrine Alterations and Perceived Stress in Patients With Poly Cystic Ovary Syndrome
Not yet reported Khyber Medical University Peshawar 147 participants Est. completion 2020-01-30 1 siteOther conditions: PCOSView official trial listing → -
Active, not recruiting NCT NCT04114682
Longitudinal Assessment of Multiple Organs in Patients With Type 2 Diabetes
Perspectum 135 participants Est. completion 2026-09-30 4 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04120259
Effect of Apple Cider Vinegar and Metformin Combination vs Metformin Alone in Type 2 Diabetics
Not yet reported Ziauddin University 126 participants Est. completion 2019-08-26 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04131582
Effect of Empagliflozin + Linagliptin + Metformin + Lifestyle in Patients With Prediabetes
Not yet reported Universidad de Guanajuato 34 participants Est. completion 2020-12-30 1 site Stand-aloneOther conditions: Prediabetic State, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT04134650
Effect of Low Dose Combination of Linagliptin + Metformin to Prevent Diabetes
Not yet reported Universidad de Guanajuato 34 participants Est. completion 2020-07-01 1 site Stand-aloneOther conditions: Prediabetic State, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT04141163
Metformin in Patients With Fragile X
Not yet reported, Not yet reported Rowan University 40 participants Est. completion 2021-03 1 site Stand-aloneOther conditions: Fragile X SyndromeView official trial listing → -
Completed NCT NCT04143282
Evaluation of the Effect of Metformin on Metastatic Breast Cancer as Adjuvant Treatment
Not yet reported Hager salah el din 250 participants Est. completion 2020-06-30 1 site Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT04145687
Metformin In Prevention of Lupus Nephritis
Not yet reported RenJi Hospital 30 participants Est. completion 2022-06 1 siteOther conditions: Lupus NephritisView official trial listing → -
Status unknown NCT NCT04146155
Efficacy and Safety of Liraglutide in Type 2 Diabetes With Lower Extremity Arterial Disease
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 200 participants Est. completion 2021-12-31 1 siteType 2 diabetes Other conditions: Peripheral Vascular Disorder Due to Diabetes MellitusView official trial listing → -
Completed NCT NCT04148183
Effect of Metformin and Rosiglitazone Over no Diabetic With Metabolic Syndrome Patients.
Not yet reported, Not yet reported J JESUS VENEGAS, MD 30 participants Est. completion 2009-01-01 Stand-aloneOther conditions: Insulin ResistanceView official trial listing → -
Status unknown NCT NCT04151459
Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients
Not yet reported RenJi Hospital 18 participants Est. completion 2022-01-15 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Severe Obesity, Laparoscopic Sleeve GastrectomyView official trial listing → -
Status unknown NCT NCT04155164
Effect of Metformin on Visual Function in Patients With Glaucoma
Not yet reported Zhongshan Ophthalmic Center, Sun Yat-sen University 40 participants Est. completion 2024-05 1 site Stand-aloneOther conditions: Primary Open Angle GlaucomaView official trial listing → -
Completed NCT NCT04156750
A Study of LY3556050 in Healthy Participants
Not yet reported Eli Lilly and Company 34 participants Est. completion 2020-08-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT04161404
Pharmacometabolomics of Andrographis Paniculata And Metformin In Healthy Volunteers Under Fasting Condition
Not yet reported University of Malaya 18 participants Est. completion 2020-12-31 1 site Stand-aloneOther conditions: Pharmacokinetics, Molecular Mechanisms of Pharmacological ActionView official trial listing → -
Completed NCT NCT04170439
Added Value of N Acetyle Cysteine to Clomiphene Citrate in PCO
Not yet reported Aljazeera Hospital 108 participants Est. completion 2020-05-15 2 sitesOther conditions: PCOView official trial listing → -
Completed NCT NCT04170465
Role of Adding Metformin to Neoadjuvant Chemotherapy in Patients With Breast Cancer (METNEO)
Not yet reported Damanhour University 70 participants Est. completion 2022-06-28 1 site Stand-aloneOther conditions: Breast Cancer FemaleView official trial listing → -
Terminated NCT NCT04170959
The Addition of Metformin to Definitive Radiotherapy in Patients With Stage III NSCLC
Not yet reported ethisch.comite@uza.be 3 participants Est. completion 2021-01-08 1 siteOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT04170998
Efficacy and Safety of Evogliptin When Added to Ongoing Metformin and Dapagliflozin Combination Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control
Not yet reported Dong-A ST Co., Ltd. 283 participants Est. completion 2021-12-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04175964
Role of the Ketogenic Diet in Women With PCOS
Not yet reported National Research Centre, Egypt 240 participants Est. completion 2023-06-30 Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT04177303
Incretin Hormones in Type 1 Diabetes Mellitus;Effect of Metformin Treatment
Not yet reported Hellenic Institute for the Study of Sepsis 44 participants Est. completion 2022-11-29 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT04181307
A Randomized Trial of a BE-EHR Module to Guide the Care of Older Adults With Diabetes
Not yet reported NYU Langone Health 7630 participants Est. completion 2022-07-01 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT04182321
Metformin as Add-on to the Standard Therapy in Patients With Chronic Hepatitis B
Not yet reported Fu-Sheng Wang 60 participants Est. completion 2021-09-13 1 site Stand-aloneOther conditions: Chronic Hepatitis BView official trial listing → -
Completed NCT NCT04183868
Effects of empagliFlozin on myocardIal metabOlic Rate of glucosE Estimated Through 18FDG PET (FIORE Study)
Not yet reported University of Catanzaro 26 participants Est. completion 2021-10 1 site Stand-aloneType 2 diabetes Other conditions: Cardiovascular Risk FactorView official trial listing → -
Completed NCT NCT04192292
Study of Sulphonylurea Synergy With DPP4 Inhibitors
Not yet reported University of Dundee 30 participants Est. completion 2020-12-02 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04194424
A Multidisciplinary Weight Loss Program at AUB-MC
Not yet reported American University of Beirut Medical Center 20 participants Est. completion 2026-09-15 1 site Stand-aloneOther conditions: Obesity, Weight LossView official trial listing → -
Status unknown NCT NCT04194515
Gut Microbiota and Bile Acids in Type 2 Diabetes Mellitus
Chang Gung Memorial Hospital 50 participants Est. completion 2021-12-31 1 siteType 2 diabetes Other conditions: Metformin, YH1View official trial listing → -
Status unknown NCT NCT04195243
Dapagliflozin vs Empagliflozin on Flow Mediated Dilation in Type 2 Diabetes Mellitus
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2020-12-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04200625
Semaglutide vs Dulaglutide on Epicardial Adipose Tissue
University of Miami 80 participants Est. completion 2019-12-09 1 siteOther conditions: Epicardial FatView official trial listing → -
Status unknown NCT NCT04204044
Comparison of Myoinositol and Metformin in PCO
Not yet reported Rashid Latif Medical College 126 participants Est. completion 2021-07-25 1 site Stand-aloneOther conditions: PCOSView official trial listing → -
Active, not recruiting NCT NCT04207944
The Prevention of Progression to Pancreatic Cancer Trial (The 3P-C Trial)
Not yet reported Duke University 100 participants Est. completion 2026-10-31 4 sites Stand-aloneOther conditions: IPMN, IPMN, PancreaticView official trial listing → -
Completed NCT NCT04209075
Prebiotics and Metformin Improve Gut and Hormones in Type 2 Diabetes in Youth (MIGHTY-fiber)
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 6 participants Est. completion 2021-07-15 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT04218734
A Study of DBPR108 and Metformin Hydrochloride Combination Therapy in Patients With T2DM
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 214 participants Est. completion 2021-06-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04220021
Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTD
Not yet reported University of Florida 41 participants Est. completion 2027-08-31 1 site Stand-aloneOther conditions: C9orf72 Amyotrophic Lateral Sclerosis (ALS), Frontotemporal DementiaView official trial listing → -
Completed NCT NCT04221750
Diet and Exercise Plus Metformin to Treat Frailty in Obese Seniors
Not yet reported VA Office of Research and Development 114 participants Est. completion 2025-07-31 1 site Stand-aloneOther conditions: Frailty, Sarcopenic Obesity, AgingView official trial listing → -
Status unknown NCT NCT04222348
MeDiGes Study: Metformine Use in Gestational Diabetes
Not yet reported Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud 200 participants Est. completion 2020-07-01 Stand-aloneOther conditions: Diabetes, Gestational, Perinatal Disorder, Puerperal DisorderView official trial listing → -
Status unknown NCT NCT04224051
Metformin for Abdominal Aortic Aneurysm Growth Inhibition
Not yet reported Uppsala University Hospital 500 participants Est. completion 2026-01 1 site Stand-aloneOther conditions: Abdominal Aortic AneurysmView official trial listing → -
Completed NCT NCT04231435
Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and Metformin
Not yet reported Celgene 24 participants Est. completion 2020-02-21 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT04233437
Drug-Drug Interaction Study of MLC1501 Using Cocktail of Drugs Acting as Sensitive Clinical Probes/Substrates of Cytochrome P450 Isoenzymes and Transporters in Healthy Subjects
Not yet reported Moleac Pte Ltd. 27 participants Est. completion 2020-05-16 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT04237493
Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan
Not yet reported University of Jordan 687 participants Est. completion 2017-07-24 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04245644
Efficacy of Chemopreventive Agents on Disease-free and Overall Survival in Patients With Pancreatic Ductal Adenocarcinoma: The CAOS Study
Massimo Falconi 800 participants Est. completion 2024-12-31 1 siteOther conditions: Disease Free Survival, Overall Survival, Pancreatic CancerView official trial listing → -
Status unknown NCT NCT04248998
Calorie Restriction With or Without Metformin in Triple Negative Breast Cancer
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 30 participants Est. completion 2024-05-01 1 site Stand-aloneOther conditions: Triple-negative Breast CancerView official trial listing → -
Status unknown NCT NCT04255238
A Study to Evaluate the Efficacy and Safety of Dual add-on Therapy With Gemigliptin 50 mg and Dapagliflozin 10 mg Added to Metformin Who Have Inadequate Glycemic Control on Metformin Alone
Not yet reported LG Chem 468 participants Est. completion 2022-12-30Type 2 diabetesView official trial listing → -
Completed NCT NCT04264897
Antecedent Metabolic Health and Metformin Aging Study
Not yet reported Oklahoma Medical Research Foundation 166 participants Est. completion 2025-03-12 2 sites Stand-aloneOther conditions: Aging, Insulin Sensitivity, Chronic Disease, Mitochondria, Insulin ResistanceView official trial listing → -
Completed NCT NCT04267809
Modulate Cellular Stress in the Immune Cells to Reduce Rate of Symptomatic Viral Infection
Not yet reported Singapore General Hospital 32 participants Est. completion 2023-07-31 1 site Stand-aloneOther conditions: Endoplasmic Reticulum Stress, Viral Infection, Yellow FeverView official trial listing → -
Completed NCT NCT04268394
A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677
Not yet reported Celgene 48 participants Est. completion 2021-06-02 1 site Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Status unknown NCT NCT04268563
Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients
Not yet reported, Not yet reported Shahid Beheshti University of Medical Sciences 80 participants Est. completion 2021-07-30 1 siteOther conditions: Polycystic Ovary Syndrome, Infertility, ARTView official trial listing → -
Completed NCT NCT04271189
Managing DIabetes Remission After Combined Therapy in EarLy Stage of DiabetEs
Not yet reported Azienda Ospedaliero-Universitaria di Parma 108 participants Est. completion 2024-12-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04272359
Substitution of Sulfonylureas With New Generation of Hypoglycemic Drugs for the Treatment of Type 2 Diabetes Mellitus
University of Milan 138 participants Est. completion 2021-12-31 1 siteType 2 diabetes Other conditions: Diet, Healthy, Renal Function Disorder, AlbuminuriaView official trial listing → -
Completed NCT NCT04275713
Altered Tumor Oxygenation by Metformin, a Potential Step in Overcoming Radiotherapy Resistance in LACC
Not yet reported Oslo University Hospital 41 participants Est. completion 2024-11-08 1 site Stand-aloneOther conditions: Cervical CancerView official trial listing → -
Completed NCT NCT04283318
Prolonged Fasting on Glucose Metabolism and Hormonal Regulation in Healthy, Obese and Subjects With Type 2 Diabetes
Not yet reported Medical University of Graz 80 participants Est. completion 2022-02-28 1 siteType 2 diabetes Other conditions: Healthy, Obesity, Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT04284722
Perioperative Continuation of Metformin Therapy in Patients With Typ 2 Diabetes Mellitus Undergoing Non-cardiac Surgery
Not yet reported Kepler University Hospital 400 participants Est. completion 2021-04Type 2 diabetes Other conditions: Hyperglycemia, Metformin, HyperlactatemiaView official trial listing → -
Status unknown NCT NCT04287387
Response of Gut Microbiota in Type 2 Diabetes to Hypoglycemic Agents
Not yet reported Peking Union Medical College Hospital 180 participants Est. completion 2021-03-02 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04288778
A Study to Assess Safety of Canagliflozin and Metformin Hydrochloride Combination Given as a Supplement to Diet and Exercise to Improve Blood Sugar Level in Indian Adult Participants With Diabetes
Not yet reported Johnson & Johnson Private Limited 276 participants Est. completion 2022-07-26 10 sites Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04295031
Metformin in Older Adults With Type 2 Diabetes (AMEMET)
Associazione Medici Endocrinologi 1500 participants Est. completion 2021-03-15 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04298684
Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules in Type 2 Diabetes
Not yet reported Centre Hospitalier Universitaire de la Guadeloupe 90 participants Est. completion 2024-07-01 4 sites Stand-aloneType 2 diabetes Other conditions: Thyroid Nodule (Benign)View official trial listing → -
Completed NCT NCT04300790
Study to Evaluate the Effect of Metformin in the Prevention of HG in HR[+]/HER2[-] PIK3CA-mut Advanced BC Patients
Not yet reported MedSIR 69 participants Est. completion 2025-03-16 19 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT04317703
Bioequivalence Study for Fixed Dose Combination Zemimet® SR Tab. 50/1000 and Coadministration of Gemigliptin 50 mg and Metformin 1000 mg.
Not yet reported LG Chem 40 participants Est. completion 2020-09-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04326166
Observational Study to Evaluate the Efficacy and Safety of Suganon Tab. or Sugamet XR Tab.
Dong-A ST Co., Ltd. 1971 participants Est. completion 2021-07-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04332393
Metformin to Treat Corticosteroids-induced Hyperglycemia
Not yet reported The Baruch Padeh Medical Center, Poriya 187 participants Est. completion 2025-05-05 4 sites Stand-aloneOther conditions: Pregnancy Preterm, Glycemic Control, Corticosteroids Induced HyperglycemiaView official trial listing → -
Completed NCT NCT04335526
A Clinical Study to Assess the Effect of Change of Bile Acid on the PD and Safety of Metformin and Microbiome Profiles
Not yet reported Seoul National University Hospital 15 participants Est. completion 2020-10-21 1 siteOther conditions: Human MicrobiomeView official trial listing → -
Active, not recruiting NCT NCT04341571
Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes.
Not yet reported University of Guadalajara 30 participants Est. completion 2026-12 1 site Stand-alonePrediabetes Other conditions: Hyperglycemia, Resistance, InsulinView official trial listing → -
Completed NCT NCT04343872
Preventing Diabetes in the Deep South: Extending Partnerships and Adapting Interventions to Reach Rural Communities at High Risk.
Not yet reported University of Alabama at Birmingham 36 participants Est. completion 2022-12-31 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT04356742
Efficacy and Safety of Dapagliflozin When Added to Ongoing Metformin and Evogliptin Combination Therapy in Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control
Not yet reported Dong-A ST Co., Ltd. 198 participants Est. completion 2022-02-23 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04373967
Study to Assess the Efficacy and Safety of Liraglutide in the Treatment of Type 2 Diabetes
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 424 participants Est. completion 2021-12-02 46 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04377321
Colchicine Has Anti-diabetic Effect
Ministry of Health and Population, Egypt 150 participants Est. completion 2020-05-02 1 siteOther conditions: Treatment AdherenceView official trial listing → -
Completed NCT NCT04377451
Metformin in Dengue With Obesity
Not yet reported, Not yet reported Oxford University Clinical Research Unit, Vietnam 120 participants Est. completion 2023-08-01 1 site Stand-aloneOther conditions: Dengue, Viral Infection, Metformin, Anti-inflammatory Agents, Obesity, OverweightView official trial listing → -
Status unknown NCT NCT04387630
Neoadjuvant Chemotherapy With or Without Metformin in Early Breast Cancer.
Not yet reported, Not yet reported Mansoura University 120 participants Est. completion 2023-05-01 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT04390295
Efficacy and Safety of SHR3824 in Combination With Metformin in Subjects With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 450 participants Est. completion 2020-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04392284
Developing an Adaptive Lifestyle Intervention Program in Family Medicine Clinics
Not yet reported University of Alabama at Birmingham 40 participants Est. completion 2022-06-03 1 site Stand-aloneMetabolic syndrome Other conditions: Insulin Resistance, Obesity, Diabetes, Hypertension, DyslipidemiasView official trial listing → -
Status unknown NCT NCT04392557
Anti-inflammatory Status in DM2 Treated Patients
Not yet reported University of Catanzaro 36 participants Est. completion 2021-06-20 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04407650
Ursodeoxycholic Acid vs Metformin in Gestational Diabetes Mellitus
Not yet reported King's College London 64 participants Est. completion 2025-05-31 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT04409795
Oral Hypoglycemic Therapy for Monogenic Variant Carriers of the Joslin Medalist Study
Not yet reported, Not yet reported Joslin Diabetes Center 3 participants Est. completion 2024-12-31 1 siteOther conditions: Type 1 Diabetes, Monogenic DiabetesView official trial listing → -
Status unknown NCT NCT04412746
Covid-19 and Diabetes in West of Algeria
Laboratoire De Recherche Sur Le Diabete, Université de Tlemcen 100 participants Est. completion 2020-06-30 1 siteOther conditions: Coronavirus Infections, Diabetes Mellitus, Prevalence, Risk Factors, Patient Outcome Assessment, Severe Acute Respiratory SyndromeView official trial listing → -
Terminated NCT NCT04416269
Oral Anti Diabetic Agents in the Hospital
Not yet reported Emory University 85 participants Est. completion 2025-04-11 3 sites Added to GLP-1Other conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04419337
Pioglitazone and SGLT2 Inhibitors vs. DPP4 Inhibitors in Patients With Stroke
Not yet reported Chang Gung Memorial Hospital 200 participants Est. completion 2024-01-31 1 site Stand-aloneCardiovascular disease Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT04428086
A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects.
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 19 participants Est. completion 2021-08-22 1 site Stand-aloneOther conditions: Solid Tumor, AdultView official trial listing → -
Completed NCT NCT04448821
A Clinical Trial to Evaluate the Effect of Nilotinib on the PK/PD of Meformin
Not yet reported Hyewon Chung 16 participants Est. completion 2020-09-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Active, not recruiting NCT NCT04451837
Semaglutide and Dapagliflozin in Diabetic Patients With Different Pathophysiology
Not yet reported Region Skane 200 participants Est. completion 2026-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04465877
Study to Evaluate Safety, Tolerability, Pharmacokinetics & Pharmacodynamics of JTT-662 in Subjects With Type 2 Diabetes
Not yet reported Akros Pharma Inc. 37 participants Est. completion 2021-02-17 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT04468243
Pilot RCT Feasibility Study: Cancer and T2D
Not yet reported University of Florida 3 participants Est. completion 2021-12-13 1 site Stand-aloneType 2 diabetes Other conditions: CancerView official trial listing → -
Status unknown NCT NCT04477590
Interactions of Medicine and Exercise With Meal Timing
Not yet reported University of Castilla-La Mancha 160 participants Est. completion 2024-12-30 1 siteMetabolic syndrome Other conditions: Exercise Training, Metformin, Statins, Angiotensin-Converting-Enzyme Inhibitor, Fasting, Intermittent, Angiotensin HypertensionView official trial listing → -
Status unknown NCT NCT04485845
Metformin Versus Vildagliptin in Reducing Risk of Metabolic Syndrome Complications Progression
Not yet reported Cairo University 39 participants Est. completion 2020-09-30 1 site Stand-aloneMetabolic syndrome Other conditions: Diabete Type 2, Kidney InsufficiencyView official trial listing → -
Completed NCT NCT04489147
Effect of Metformin on Non PCO Women Undergoing IVF/ICSI
Not yet reported Kasr El Aini Hospital 400 participants Est. completion 2020-11-27 1 siteOther conditions: InfertilityView official trial listing → -
Completed NCT NCT04497792
Safety and Efficacy of Empagliflozin for Patients With Diabetes Mellitus and Planned Percutaneous Coronary Interventions
Not yet reported Research Institute for Complex Problems of Cardiovascular Diseases, Russia 40 participants Est. completion 2019-11Cardiovascular disease Other conditions: Diabetes Mellitus, Percutaneous Coronary InterventionView official trial listing → -
Status unknown NCT NCT04502303
18F-FDG and 68Ga-FAPI PET/CT in Crohn's Disease
Not yet reported Peking Union Medical College Hospital 30 participants Est. completion 2021-09 Stand-aloneOther conditions: Crohn DiseaseView official trial listing → -
Terminated NCT NCT04504045
Metformin's Effect on Drug Metabolism in Patients With Type 2 Diabetes
Not yet reported University of Southern Denmark 10 participants Est. completion 2022-05-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04504396
Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy
Not yet reported PegBio Co., Ltd. 620 participants Est. completion 2023-05-26 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04508634
Treating Obese PCOS Patients With LSG vs. Met
Not yet reported Shanghai 10th People's Hospital 90 participants Est. completion 2024-09-30 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04510194
COVID-OUT: Early Outpatient Treatment for SARS-CoV-2 Infection (COVID-19)
Not yet reported University of Minnesota 1323 participants Est. completion 2022-12-14 7 sites Stand-aloneOther conditions: Covid19, SARS-CoV InfectionView official trial listing → -
Active, not recruiting NCT NCT04511416
Preventing Cognitive Decline with Metformin
Not yet reported Garvan Institute of Medical Research 242 participants Est. completion 2027-12 1 siteOther conditions: Cognitive DeclineView official trial listing → -
Completed NCT NCT04521049
Tubular Markers in Response to Saxagliptin Therapy
Not yet reported Beni-Suef University 80 participants Est. completion 2020-04-01 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT04530058
The Effects of Metformin on Morbidity and Mortality in Elderly Patients
Not yet reported Hamilton Health Sciences Corporation 250 participants Est. completion 2029-03 1 site Stand-aloneOther conditions: BurnsView official trial listing → -
Active, not recruiting NCT NCT04536805
Relapse in Previously Irradiated Prostate Bed : Stereotactic Ablative Reirradiation Potentiated by Metformin
Not yet reported, Not yet reported Institut Cancerologie de l'Ouest 44 participants Est. completion 2031-11 12 sites Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT04537923
A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin
Not yet reported Eli Lilly and Company 1428 participants Est. completion 2022-11-01 135 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04545736
Oral Metformin for Treatment of ABCA4 Retinopathy
Not yet reported, Not yet reported National Eye Institute (NEI) 55 participants Est. completion 2029-02-02 2 sites Stand-aloneOther conditions: ABCA4 Retinopathy, Stargardt Disease, Retinal Dystrophy, Retinal DegenerationView official trial listing → -
Completed NCT NCT04549415
The Influence of Metformin on Chronic Heart Failure Clinical Course in Patients With Prediabetes
Not yet reported National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov 97 participants Est. completion 2019-11-15 1 siteHeart failureCardiovascular diseasePrediabetesView official trial listing → -
Status unknown NCT NCT04559308
The Effect of Metformin on Breast Cancer Patients
Not yet reported Beni-Suef University 80 participants Est. completion 2020-10 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT04566718
A Treatment Legacy Effect of Metformin in Obese Women With PCOS
University Medical Centre Ljubljana 40 participants Est. completion 2020-02-01 1 siteOther conditions: PCOSView official trial listing → -
Withdrawn NCT NCT04569214
The Efficacy and Safety of PAZ320 on PPG and Insulin Blood Levels in Type II Diabetic Patients
Not yet reported Boston Therapeutics Est. completion 2013-02 1 siteOther conditions: Type II DiabetesView official trial listing → -
Active, not recruiting NCT NCT04576104
Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer
Not yet reported Northwestern University 51 participants Est. completion 2026-06-30 8 sites Stand-aloneOther conditions: Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, Endometrial CarcinomaView official trial listing → -
Active, not recruiting NCT NCT04583462
Impact of Metformin on Peripheral Arterial Calcification in Type 1 Diabetes
Not yet reported Assistance Publique - Hôpitaux de Paris 230 participants Est. completion 2027-10-29 1 site Stand-aloneOther conditions: Type 1 Diabetes, Peripheral Arterial CalcificationView official trial listing → -
Completed NCT NCT04588259
Research Study to Compare a New Medicine "Fast-acting Insulin Aspart" to Another Medicine "Insulin Aspart" in Chinese People With Diabetes
Not yet reported Novo Nordisk A/S 331 participants Est. completion 2022-08-05 40 sites Stand-aloneType 2 diabetes Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT04591626
A Study of Dulaglutide (LY2189265) in Chinese Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 291 participants Est. completion 2022-04-28 27 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT04593459
Probiotic Intervention in PCOS
Not yet reported Medical University of Graz 112 participants Est. completion 2023-10-16 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04596631
A Research Study to Compare a New Medicine Oral Semaglutide to a Dummy Medicine in Children and Teenagers With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 132 participants Est. completion 2026-02-03 97 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Terminated NCT NCT04607252
Metformin Plus Megestrol Acetate As a Fertility-sparing Treatment in Patients with Atypical Endometrial Hyperplasia
Not yet reported, Not yet reported Fudan University 12 participants Est. completion 2021-06-03 1 site Stand-aloneOther conditions: Atypical Endometrial HyperplasiaView official trial listing → -
Status unknown NCT NCT04615351
A Pragmatic Approach to Lowering the Risk of Diabetes Mellitus After A Diagnosis of Gestational Diabetes Mellitus
Not yet reported Women and Infants Hospital of Rhode Island 200 participants Est. completion 2022-06-30 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT04617275
A 12-WEEK TITRATE STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06882961 IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND IN NON-DIABETIC ADULTS WITH OBESITY
Not yet reported Pfizer 151 participants Est. completion 2021-11-17 38 sitesOther conditions: Diabetes, ObesityView official trial listing → -
Status unknown NCT NCT04621656
Sugar Challenge Study
January, Inc. 1022 participants Est. completion 2021-10 1 siteType 2 diabetesPrediabetes Other conditions: HealthyView official trial listing → -
Completed NCT NCT04621669
Drug-durg Interaction of SHR3680 With Digoxin, Rosuvastatin Calcium and Metformin Hydrochloride
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 36 participants Est. completion 2021-09-08 1 site Stand-aloneOther conditions: Drug-drug Interaction,SHR3680View official trial listing → -
Completed NCT NCT04622111
Safety and Pharmacokinetics Study of CPL207280 Compound in Healthy Volunteers.
Not yet reported Celon Pharma SA 68 participants Est. completion 2021-05-05 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT04623567
Efficacy Assessment of Chinese Herbal Medicine Jiangtang Tiaozhi Recipe Treating Participants With Glucose and Lipid Metabolism Disturbances
Not yet reported, Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 96 participants Est. completion 2024-06-30 1 siteType 2 diabetes Other conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT04625946
Metformin as an Adjunctive Therapy to Catheter Ablation in Atrial Fibrillation
Not yet reported University of Michigan 117 participants Est. completion 2025-08-10 1 site Stand-aloneOther conditions: Atrial FibrillationView official trial listing → -
Completed NCT NCT04625985
Metformin Glycinate, Treatment of Patients With COVID-19 and Severe Acute Respiratory Syndrome Secondary to SARS-CoV-2.
Not yet reported Laboratorios Silanes S.A. de C.V. 20 participants Est. completion 2021-03-18 1 site Stand-aloneOther conditions: Severe Acute Respiratory Syndrome Coronavirus 2View official trial listing → -
Withdrawn NCT NCT04626089
Metformin Glycinate in Patients With MS or DM2 , Hospitalized With COVID-19 and SARS Secondary to SARS-CoV-2
Not yet reported Laboratorios Silanes S.A. de C.V. Est. completion 2021-02 1 site Stand-aloneMetabolic syndromeType 2 diabetes Other conditions: Severe Acute Respiratory Syndrome Coronavirus 2View official trial listing → -
Status unknown NCT NCT04626323
Randomized Study Comparing Metabolic Surgery With Intensive Medical Therapy to Treat Diabetic Kidney Disease
Not yet reported Hospital Alemão Oswaldo Cruz 60 participants Est. completion 2024-12 1 site Stand-aloneType 2 diabetes Other conditions: Kidney Disease, Chronic, Kidney InjuryView official trial listing → -
Completed NCT NCT04631289
Preadmission Metformin Exposure and Incidence of Acute Kidney Injury
Second Affiliated Hospital of Guangzhou Medical University 3841 participants Est. completion 2020-11-10 1 siteOther conditions: AKIView official trial listing → -
Completed NCT NCT04634890
Bialystok Exercise Study in Diabetes
Not yet reported Medical University of Bialystok 300 participants Est. completion 2023-12-20 1 siteType 2 diabetesPrediabetes Other conditions: Overweight, Obesity, DyslipidemiasView official trial listing → -
Completed NCT NCT04639492
Postbiotic MBS and Metformin Combination in Patients With T2DM
Not yet reported Microbio Co Ltd 14 participants Est. completion 2022-09-23 1 siteOther conditions: Type-II DiabetesView official trial listing → -
Completed NCT NCT04640571
Impact of Metformin and Polysorbate 80 on Drug Absorption and Disposition
Not yet reported University of Maryland, Baltimore 18 participants Est. completion 2021-11-01 1 site Stand-aloneOther conditions: Bile Salt Export Pump (BSEP) Transporter, Polysorbate 80View official trial listing → -
Completed NCT NCT04649502
Metformin for the Treatment of Hidradenitis Suppurativa (HS)
Not yet reported K.R. van Straalen 62 participants Est. completion 2023-08-23 1 site Stand-aloneOther conditions: Hidradenitis SuppurativaView official trial listing → -
Status unknown NCT NCT04653779
A Clinical Trial to Evaluate the Preference Regarding Convenience of Medication and Efficacy/Safety of SUGAMET®XR Tablet 5/1000mg
Not yet reported Dong-A ST Co., Ltd. 54 participants Est. completion 2021-07 2 sites Stand-aloneType 2 diabetes Other conditions: Renal Disease, Diabetes Mellitus, Metabolic Disease, Endocrine System DiseasesView official trial listing → -
Completed NCT NCT04654676
DPP4 Inhibitor on Glycemic Variability
Not yet reported University Malaysia Sarawak 12 participants Est. completion 2019-08-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04659915
Counteracting Deleterious Metabolic Glucocorticoid Effects With Metformin
Not yet reported Eleonora Seelig 19 participants Est. completion 2021-08-18 1 site Stand-aloneOther conditions: Glucocorticoid EffectView official trial listing → -
Withdrawn NCT NCT04662164
A Study to Access the Efficacy in Type 2 Diabetes Mellitus on Stable Metformin
Not yet reported, Not yet reported Shanghai HEP Pharmaceutical Co., Ltd. Est. completion 2025-12Type 2 diabetesView official trial listing → -
Status unknown NCT NCT04662866
Effects of Glucose Lowering Agents in South Asian Women With Impaired Glucose Tolerance or Impaired Fasting Glucose
Not yet reported Oslo University Hospital 64 participants Est. completion 2023-10 1 sitePrediabetes Other conditions: Insulin Sensitivity, Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT04665570
A Study to Learn More About How Acarbose and Metformin Work When Taken Together and How Safe They Are in Indian Patients Who Were Recently Diagnosed With Type 2 Diabetes (T2D)
Bayer 2000 participants Est. completion 2024-09-05 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04667143
Dual Add-on Therapy in Type 2 Diabetes Poorly Controlled With Metformin Monotherapy
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 760 participants Est. completion 2022-10 Stand-aloneOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT04671953
Effect of BMS-986165 on the Blood Levels of Metformin
Not yet reported Bristol-Myers Squibb 36 participants Est. completion 2021-03-30 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Status unknown NCT NCT04672031
Glycemic Targets for Pregnant Women With GDM and T2DM
Not yet reported University of Southern California 120 participants Est. completion 2023-07 1 site Stand-aloneType 2 diabetes Other conditions: Diabetes Mellitus in Pregnancy, Diabetes, GestationalView official trial listing → -
Completed NCT NCT04684420
GXR RM (Glucophage® Extended Release Reduced Mass) 500 Milligram (mg) Korea Bioequivalence (BE) Study
Not yet reported Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 81 participants Est. completion 2022-03-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Active, not recruiting NCT NCT04691960
A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging
Not yet reported Weill Medical College of Cornell University 18 participants Est. completion 2026-06 2 sites Stand-aloneOther conditions: GlioblastomaView official trial listing → -
Completed NCT NCT04700839
SGLT2 Inhibitors in Patients With PCOS
Not yet reported Shanghai 10th People's Hospital 68 participants Est. completion 2021-04-30 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04706377
Vitamin B12 Supplementation in Diabetic Neuropathy
Not yet reported Aristotle University Of Thessaloniki 90 participants Est. completion 2020-02-28 1 siteOther conditions: Diabetes Mellitus, Diabetic Neuropathies, Diabetic Complication, Diabetic FootView official trial listing → -
Completed NCT NCT04738799
The Impact of Food Order on Glycemic Excursions in Type 2 Diabetes Assessed by Continuous Glucose Monitoring
Not yet reported Weill Medical College of Cornell University 20 participants Est. completion 2023-07-03 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT04741204
Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer
Not yet reported Woman's Est. completion 2022-09 1 site Stand-aloneOther conditions: Breast Cancer Stage, Insulin Resistance, Racial BiasView official trial listing → -
Active, not recruiting NCT NCT04742751
An Open-Label Pilot Intervention Trial to Prevent Diabetes in Prediabetic Adult Survivors of Childhood Cancer
Not yet reported St. Jude Children's Research Hospital 96 participants Est. completion 2027-03 1 site Stand-alonePrediabetes Other conditions: Adult ChildrenView official trial listing → -
Status unknown NCT NCT04750135
Assessment of Metformin as Adjuvant Therapy in Patients With Ulcerative Colitis
Not yet reported National Hepatology & Tropical Medicine Research Institute 40 participants Est. completion 2021-06-01 1 site Stand-aloneOther conditions: Ulcerative Colitis, Inflammatory Bowel DiseasesView official trial listing → -
Terminated NCT NCT04754334
A Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus
Not yet reported Oramed, Ltd. 346 participants Est. completion 2023-01-13 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04762966
Study of Metformin Overdose
Central Hospital, Nancy, France 50 participants Est. completion 2021-09-01 1 siteOther conditions: Metformin Associated Lactic AcidosisView official trial listing → -
Status unknown NCT NCT04766008
Metformin in Diabetic Patients Undergoing Coronary Angiography
Not yet reported Humanitas Hospital, Italy 150 participants Est. completion 2022-04-30 1 site Stand-aloneCardiovascular disease Other conditions: Diabetes Mellitus, Lactic Acidosis With Diabetes Mellitus, Contrast-induced Nephropathy, Metformin Associated Lactic AcidosisView official trial listing → -
Withdrawn NCT NCT04767841
The AMPK Modulator Metformin as a Novel Adjunct to Conventional Therapy in Patients With Knee Osteoarthritis
Not yet reported, Not yet reported Sadat City University Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Osteo Arthritis KneeView official trial listing → -
Status unknown NCT NCT04780854
Drug Repurposing for the Prevention of Chemotherapy-induced Peripheral Neuropathy (CIPN)
Not yet reported Cairo University 68 participants Est. completion 2022-07 1 siteOther conditions: Chemotherapy-induced Peripheral NeuropathyView official trial listing → -
Status unknown NCT NCT04792749
Clinical Effects of Metformin on Fertility-sparing Treatment for Early Endometrial Cancer
Not yet reported Samsung Medical Center 77 participants Est. completion 2024-03-31 1 site Stand-aloneOther conditions: Endometrial Cancer Stage IView official trial listing → -
Status unknown NCT NCT04796428
GliflOzin in eLderly Diabetic patiENts: A praGmatic Intraclass Evaluation Trial
Not yet reported Center for Outcomes Research and Clinical Epidemiology, Italy 1167 participants Est. completion 2023-12-31Type 2 diabetesView official trial listing → -
Status unknown NCT NCT04799938
Effect of Exercise on GDF-15 Levels in Prediabetic Patients
Not yet reported Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey 70 participants Est. completion 2023-04-01 1 sitePrediabetesView official trial listing → -
Completed NCT NCT04807348
Chiglitazar Added to Metformin for Type 2 Diabetes
Not yet reported Chipscreen Biosciences, Ltd. 533 participants Est. completion 2023-02-10 50 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04809311
Remote Study Collecting Blood Glucose Values and Activity Data in Patients With Type 2 Diabetes on Different Treatments
Novo Nordisk A/S 156 participants Est. completion 2025-01-07 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04817215
Phase 3 Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus
Not yet reported King Hamad University Hospital, Bahrain 608 participants Est. completion 2022-07 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04826692
TEsting METformin Against Cognitive Decline in HD
Not yet reported Instituto de Investigacion Sanitaria La Fe 60 participants Est. completion 2025-06-10 9 sites Stand-aloneOther conditions: Huntington DiseaseView official trial listing → -
Completed NCT NCT04829903
Dulaglutide Versus Liraglutide in Obese Type 2 Diabetic Adolescents Using Metformin
Not yet reported Corporacion Parc Tauli 116 participants Est. completion 2021-11-20 1 siteType 2 diabetes Other conditions: Obesity, Adolescent ObesityView official trial listing → -
Not yet recruiting NCT NCT04836910
Microbiome and Polycystic Ovaries
Sheba Medical Center 40 participants Est. completion 2027-03-30 1 siteOther conditions: Polycystic Ovary Syndrome, Microbial ColonizationView official trial listing → -
Withdrawn NCT NCT04839237
The Effect and the Pharmacogenomics Study of Liraglutide in Obese Patients
Not yet reported Xiangya Hospital of Central South University Est. completion 2021-12-01 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT04841096
Oral Combination of Glimepiride/Vildagliptin/Metformin in Patients With T2D and Dual Treatment Failure
Not yet reported Laboratorios Silanes S.A. de C.V. 162 participants Est. completion 2024-05-15 5 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04841668
Gut-Brain-axis: Targets for Improvement of Cognition in the Elderly
Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta 50 participants Est. completion 2024-12-03 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04850846
Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma
Not yet reported Dana-Farber Cancer Institute 60 participants Est. completion 2027-07-31 7 sites Stand-aloneOther conditions: Monoclonal Gammopathy of Undetermined Significance, Smoldering Multiple MyelomaView official trial listing → -
Completed NCT NCT04852510
Amelioration of Polycystic Ovary Syndrome Related Disorders by Supplementation of Thymoquinone and Metformin
Not yet reported, Not yet reported Saudi German Hospital - Madinah 253 participants Est. completion 2020-08-31 1 siteOther conditions: Polycystic Ovary Syndrome (PCOS)View official trial listing → -
Suspended NCT NCT04854512
Investigational Study of Delayed Release Metformin
Not yet reported Anji Pharma 675 participants Est. completion 2024-06-30 87 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04855513
Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial
Not yet reported Hamad Medical Corporation 414 participants Est. completion 2023-12-30 1 site Stand-aloneOther conditions: Preeclampsia, Preeclampsia Severe, High Risk Pregnancy, EclampsiaView official trial listing → -
Completed NCT NCT04856007
A Study to Assess the Bioequivalence of Fixed Dose Combination of Dapagliflozin/Metformin XR Relative to Co-administration of the Individual Components in Healthy Chinese Subjects.
Not yet reported AstraZeneca 80 participants Est. completion 2021-06-14 1 site Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Completed NCT NCT04859452
A Study to Evaluate the DDI of DBPR108 With Metformin,Glibenclamide,Valsartan, or Simvastatin in Healthy Subjects
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 56 participants Est. completion 2021-07-09 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT04862390
Incidence of Hypoglycemia in Pregnant Ladies With or Without Gestational Diabetes Fasting Ramadan
King Abdullah International Medical Research Center 30 participants Est. completion 2021-08-01 1 siteOther conditions: Pregnancy in DiabeticView official trial listing → -
Completed NCT NCT04865835
A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia.
Not yet reported Otsuka Pharmaceutical Development & Commercialization, Inc. 21 participants Est. completion 2022-05-03 2 sites Stand-aloneOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT04866667
Observational Study of ASCVD Risks of Type 2 Diabetes in East China
Zhejiang Provincial People's Hospital 316 participants Est. completion 2024-05-31 1 siteType 2 diabetesCardiovascular disease Other conditions: LiraglutideView official trial listing → -
Completed NCT NCT04867252
Effects of Combined Resveratrol and Myo-inositol on Altered Metabolic, Endocrine Parameters and Perceived Stress in Patients With Polycystic Ovarian Syndrome
Not yet reported Khyber Medical University Peshawar 88 participants Est. completion 2021-08-03 1 siteOther conditions: PCOSView official trial listing → -
Active, not recruiting NCT NCT04869917
Behavioral Nudges for Diabetes Prevention (BEGIN) Trial in Primary Care
Not yet reported Northwestern University 960 participants Est. completion 2026-09-01 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT04877106
Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects
Not yet reported The Affiliated Hospital of Qingdao University 48 participants Est. completion 2018-07-31 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT04879511
Effect of Metformin in Children With Type 1 Diabetes
Not yet reported, Not yet reported Ain Shams University 80 participants Est. completion 2021-01-29 1 siteOther conditions: Effect of Change in T1DM Glycemic ControlView official trial listing → -
Status unknown NCT NCT04882332
Metformin Usage Index and Vitamin B12 Status in Egyptian Type 2 Diabetic Patients
Cairo University 108 participants Est. completion 2022-10 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04885426
Metformin for the Prevention of CRA Recurrence
Not yet reported Jing-yuan Fang, MD, Ph. D 414 participants Est. completion 2022-11 1 site Stand-aloneOther conditions: Colorectal Adenoma, Metformin, ChemopreventionView official trial listing → -
Completed NCT NCT04885530
ACTIV-6: COVID-19 Study of Repurposed Medications
Not yet reported Susanna Naggie, MD 10956 participants Est. completion 2024-04-29 110 sites Stand-aloneOther conditions: Covid19View official trial listing → -
Completed NCT NCT04885712
A Study to Evaluate the Efficacy and Safety of Pioglitazone 15mg or 30mg Add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
Not yet reported Boryung Pharmaceutical Co., Ltd 378 participants Est. completion 2023-03-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04893148
Efficacy and Safety of iGlarLixi Versus Insulin Glargine Plus Dulaglutide in Patients With Type 2 Diabetes
Not yet reported Chungbuk National University Hospital 40 participants Est. completion 2022-12-30 1 siteType 2 diabetes Other conditions: Glucose, High BloodView official trial listing → -
Active, not recruiting NCT NCT04897945
A Shared Decision Making Intervention for Diabetes Prevention in Women With a History of Gestational Diabetes Mellitus
Not yet reported University of California, Los Angeles 310 participants Est. completion 2026-10-01 2 sites Stand-alonePrediabetesType 2 diabetes Other conditions: Gestational Diabetes MellitusView official trial listing → -
Terminated NCT NCT04899349
Study of Safety and Efficacy of Dapagliflozin + Metformin XR Versus Metformin XR in Participants With HR+, HER2-, Advanced Breast Cancer While on Treatment With Alpelisib and Fulvestrant
Not yet reported Novartis Pharmaceuticals 2 participants Est. completion 2023-05-10 2 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT04902326
Behavioral Economics and Self-Determination Theory to Change Diabetes Risk (BEST Change)
Not yet reported University of Michigan 380 participants Est. completion 2023-09-18 1 site Stand-aloneOther conditions: Pre DiabetesView official trial listing → -
Completed NCT NCT04907708
Comparative Effects of Metformin and Insulin on Stereological Studies and Immunohistochemistry of Placenta
Not yet reported University of Karachi 156 participants Est. completion 2019-08-07 1 site Stand-aloneOther conditions: Diabetes Mellitus Arising in Pregnancy, Insulin-Requiring, Diabetes Mellitus in PregnancyView official trial listing → -
Completed NCT NCT04916093
Safety and Efficacy of Antidiabetic Drugs in Recently Diagnosed Patients With Type 2 Diabetes
Not yet reported Beni-Suef University 60 participants Est. completion 2020-12-15 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04925063
The Effect of Metformin in Patients With Newly Diagnosed mHSPC
Not yet reported Sun Yat-sen University 266 participants Est. completion 2027-01-31 1 site Stand-aloneOther conditions: Metastatic Prostate CancerView official trial listing → -
Status unknown NCT NCT04926155
The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancer
Not yet reported Sun Yat-sen University 234 participants Est. completion 2024-08-31 1 site Stand-aloneOther conditions: Metastatic Prostate CancerView official trial listing → -
Status unknown NCT NCT04930471
Steroid and Behaviour Changes Under Metformin
Insel Gruppe AG, University Hospital Bern 45 participants Est. completion 2023-12 1 siteOther conditions: Autistic DisorderView official trial listing → -
Completed NCT NCT04930744
Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV)
Not yet reported University of Massachusetts, Worcester 112 participants Est. completion 2025-08-15 2 sites Stand-aloneOther conditions: Tuberculosis, Pulmonary Tuberculosis, HIV CoinfectionView official trial listing → -
Active, not recruiting NCT NCT04931017
Metformin for Chemoprevention of Lung Cancer in Overweight or Obese Individuals at High Risk for Lung Cancer
Not yet reported Northwestern University 50 participants Est. completion 2027-06-30 4 sites Stand-aloneOther conditions: Lung CarcinomaView official trial listing → -
Completed NCT NCT04931147
A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers
Not yet reported Redx Pharma Ltd 90 participants Est. completion 2023-03-08 1 site Stand-aloneOther conditions: Fibrosis, Inflammation, Idiopathic Pulmonary Fibrosis, Non-alcoholic Steatohepatitis, Liver Diseases, Kidney DiseasesView official trial listing → -
Completed NCT NCT04947020
DataBase for Analysis of Rectal Cancer Oncological Results
Jagiellonian University 2443 participants Est. completion 2024-12-31 1 siteOther conditions: Rectal Cancer, Metformin, Overall Survival, Lymph Node Metastases, Disease-free SurvivalView official trial listing → -
Status unknown NCT NCT04962841
Nutraceuticals and Drug Treatment in Frail Older Adults
University of Campania Luigi Vanvitelli 485 participants Est. completion 2023-04-01 1 siteOther conditions: FrailtyView official trial listing → -
Completed NCT NCT04969627
Effects of GLP-1 Analogue Combined With Metformin and Metformin on Gonadal and Metabolic Profiles in Chinese Overweight/Obese PCOS Patients With Hyperandrogenemia.
Not yet reported Bing He 60 participants Est. completion 2022-03-29 1 site MixedOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04972396
Pemvidutide (ALT-801) DDI Study in Healthy Volunteers
Not yet reported Altimmune, Inc. 40 participants Est. completion 2022-05-15 2 sites Stand-aloneMASHView official trial listing → -
Completed NCT NCT04973891
CANA/Met in Non-diabetic Women With PCOS
Not yet reported, Not yet reported Shengjing Hospital 52 participants Est. completion 2022-03-08 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT04976283
Effect of Oral Anti-diabetic Medication on Liver Fat in Subjects With Type II Diabetes and Non-alcoholic Fatty Liver
Not yet reported Getz Pharma 123 participants Est. completion 2023-11-15 1 siteType 2 diabetesMASHMASLDView official trial listing → -
Completed NCT NCT04979130
Comparing Semaglutide Versus Placebo on Intestinal Barrier Function in Type 2 Diabetes Mellitus (SIB)
Not yet reported University of Colorado, Denver 69 participants Est. completion 2024-10-16 1 site Added to GLP-1Type 2 diabetes Other conditions: Chronic Inflammation, Intestinal PermeabilityView official trial listing → -
Status unknown NCT NCT04984070
Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety
Not yet reported Fudan University 100 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, AnxietyView official trial listing → -
Withdrawn NCT NCT04994561
VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements
Not yet reported Vitality in Aging Research Group, Inc. Est. completion 2023-12 Stand-aloneOther conditions: AgingView official trial listing → -
Completed NCT NCT04998032
A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment(SUPER-2)
Not yet reported, Not yet reported Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. 620 participants Est. completion 2023-08-13 61 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05004948
Exercise Intervention Combined With Metformin in the Treatment of Type 2 Diabetes
Not yet reported Prince Sattam Bin Abdulaziz University 57 participants Est. completion 2019-10-15 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05013112
Ameliorating Metabolic Profiling After Kidney Transplantation (AMPKT)
Not yet reported West China Hospital 105 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Kidney Transplantation, Metabolic Disorder, Metformin, EmpagliflozinView official trial listing → -
Completed NCT NCT05025852
The Effect of In-utero Exposure to Metformin in 5-11 Year Old Offspring of Mothers in the MiTy Trial
Mount Sinai Hospital, Canada 132 participants Est. completion 2025-04-30 12 sitesType 2 diabetes Other conditions: Pregnancy in Diabetic, Child Obesity, Child DevelopmentView official trial listing → -
Status unknown NCT NCT05032001
ORAL ANTIDIABETICS EFFECT ON VISCERAL FAT
Not yet reported Metabolic Research Unit 30 participants Est. completion 2022-08-01 1 site Stand-aloneType 2 diabetes Other conditions: Abdominal ObesityView official trial listing → -
Completed NCT NCT05035082
A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE)
Not yet reported Novo Nordisk A/S 1018 participants Est. completion 2025-06-18 25 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05040087
Changing the Natural History of Type 2 Diabetes ("CHANGE" Study)
Not yet reported Foundation for Atlanta Veterans Education and Research, Inc. 127 participants Est. completion 2028-06-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05041673
Anti-diabetic Drugs and Fatty Liver Management
Not yet reported Alexandria University 120 participants Est. completion 2022-09-30 1 site Stand-aloneType 2 diabetes Other conditions: Fatty Liver, NonalcoholicView official trial listing → -
Completed NCT NCT05042505
Effect of Dapagliflozin vs Sitagliptin on Liver Fat Accumulation and Body Composition in Patients With Diabetes Mellitus and Liver Transplantation
Not yet reported Medanta, The Medicity, India 100 participants Est. completion 2026-02-27 1 siteOther conditions: Diabetes Mellitus, Liver Transplant; ComplicationsView official trial listing → -
Status unknown NCT NCT05052918
The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes
Not yet reported Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey 90 participants Est. completion 2023-03-15 1 siteOther conditions: Pre Diabetes, Exercise, Metformin, AtherosclerosisView official trial listing → -
Completed NCT NCT05053841
Implication of Metformin Plus Aromatase Inhibitor in Obese Postmenopausal Breast Cancer Women
Not yet reported Tanta University 45 participants Est. completion 2015-06Other conditions: Metformin, Breast CancerView official trial listing → -
Status unknown NCT NCT05054842
Clinical Study of Retagliptin Phosphate Combined With Metformin in the Treatment of Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 174 participants Est. completion 2023-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05055219
Conventional and Metabolomic Predictors of Prediabetes & Insulin Resistance
University of Michigan 772 participants Est. completion 2020-02-19 1 sitePrediabetes Other conditions: Obesity, ChildhoodView official trial listing → -
Completed NCT NCT05081583
Clinical Evaluation of the Pharmacokinetic Goldenseal-Metformin Interaction in Diabetic Patients
Not yet reported Washington State University 22 participants Est. completion 2023-08-31 1 site Stand-aloneType 2 diabetes Other conditions: Interaction, Adverse Herb-DrugView official trial listing → -
Completed NCT NCT05083949
A Study in Healthy Humans to Assess the Relative Bioavailability of One Fixed-dose Combination Tablet Empagliflozin/Metformin Versus Jardiance® Tablet and Glifage® Tablet Administered Together
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2021-09-09 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05093959
Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction
Not yet reported Wake Forest University Health Sciences 86 participants Est. completion 2026-04-16 2 sitesHeart failureView official trial listing → -
Active, not recruiting NCT NCT05098470
Effects of Modulators of Gluconeogenesis, Glycogenolysis and Glucokinase Activity
Not yet reported University of Alabama at Birmingham 100 participants Est. completion 2026-07-29 2 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT05101135
To Evaluate the Efficacy and Safety of JT-001 add-on in Paatients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
Not yet reported Jeil Pharmaceutical Co., Ltd. 256 participants Est. completion 2022-10-31 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT05102071
Clinical Outcomes and Healthcare Cost and Resource Utilization (HCRU) in Patients With Type 2 Diabetes and Cardiovascular Disease on 2nd Line Empagliflozin Versus 2nd Line Sulfonylureas
Boehringer Ingelheim Est. completion 2022-06-15 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT05103306
Empagliflozin-based Quadruple Therapy vs Basal Insulin-based Therapy
Chungbuk National University Hospital 300 participants Est. completion 2022-12Type 2 diabetesView official trial listing → -
Status unknown NCT NCT05108350
A Study to Assess the Bioequivalence of Fixed Dose Combination of HR20033 Relative to Co-administration of the Individual Components in Healthy Chinese Subjects
Not yet reported Shandong Suncadia Medicine Co., Ltd. 80 participants Est. completion 2021-12-10 Stand-aloneOther conditions: Type II DiabetesView official trial listing → -
Active, not recruiting NCT NCT05109169
METformin and FINGER Intervention to Prevent Cognitive Impairment and Disability in Older Adults at Risk for Dementia
Not yet reported Imperial College London 600 participants Est. completion 2028-06-30 3 sitesOther conditions: Cognitive Decline, Cognitive Impairment, DementiaView official trial listing → -
Completed NCT NCT05120505
Metformin in Children With Fragile X Syndrome
Not yet reported Children's Hospital of Fudan University 37 participants Est. completion 2025-01-30 1 site Stand-aloneOther conditions: Fragile X Syndrome, MetforminView official trial listing → -
Completed NCT NCT05123781
Fasting Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers
Not yet reported Joint Stock Company "Farmak" 28 participants Est. completion 2019-04-17 1 site Stand-aloneOther conditions: PharmacokineticsView official trial listing → -
Completed NCT NCT05124717
Fed Bioequivalence Study of 2 Metformin 500 mg Prolongued Release Tablets in 28 Healthy Male and Female Volunteers
Not yet reported Joint Stock Company "Farmak" 28 participants Est. completion 2019-07-03 1 site Stand-aloneOther conditions: PharmacokineticsView official trial listing → -
Completed NCT NCT05124730
Fasting Bioequivalence Study of 2 Metformin 500 mg Prolonged Release Tablets in 44 Healthy Male and Female Volunteers
Not yet reported Joint Stock Company "Farmak" 44 participants Est. completion 2021-05-29 1 site Stand-aloneOther conditions: PharmacokineticsView official trial listing → -
Completed NCT NCT05125575
Fed Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers
Not yet reported Joint Stock Company "Farmak" 28 participants Est. completion 2019-01-19 1 site Stand-aloneOther conditions: PharmacokineticsView official trial listing → -
Status unknown NCT NCT05126381
Population Pharmacokinetic - Pharmacodynamic Models of Chronic Disease Therapeutics for Smokers
The Second Affiliated Hospital of Chongqing Medical University 200 participants Est. completion 2024-04-30 1 siteOther conditions: Chronic Disease, SmokingView official trial listing → -
Completed NCT NCT05131828
CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy
Not yet reported Cambridge University Hospitals NHS Foundation Trust 70 participants Est. completion 2025-09-26 1 site Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Completed NCT NCT05132023
Bioequivalence Study of Empagliflozin & Metformin HCL From Empagliform 12.5/1000 mg F.C.T (Hikma Pharma, Egypt) and Synjardy 12.5/1000 mg F.C.T (Boehringer Ingelheim International GmbH, Germany)
Not yet reported Genuine Research Center, Egypt 26 participants Est. completion 2019-05-15 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT05147896
Semaglutide Anti-Atherosclerotic Mechanisms of Action Study in Type 2 Diabetes Patients
Not yet reported University Medical Centre Ljubljana 100 participants Est. completion 2023-12-01 1 siteType 2 diabetes Other conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT05151146
A Phase 1 Study of ANJ900 Chinese Healthy Subjects
Not yet reported Anji Pharma 18 participants Est. completion 2022-02-28 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT05158374
Molecular Effects of Aspirin & Metformin on Colonic Epithelium
Not yet reported University of Edinburgh Est. completion 2023-06Other conditions: Colorectal Cancer, Colorectal Neoplasms, Colorectal AdenomaView official trial listing → -
Status unknown NCT NCT05161429
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
Brigham and Women's Hospital 550000 participants Est. completion 2024-06-30 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05162014
To Assess the Risk of Acute Pancreatitis in Patients With Type 2 Diabetes Mellitus Treated With Empagliflozin
Boehringer Ingelheim 494679 participants Est. completion 2022-09-12 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05162690
Efficacy of Dapagliflozin in Diabetes Associated Peripheral Neuropathy
Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 40 participants Est. completion 2023-12-31 1 siteOther conditions: Diabetic Peripheral NeuropathyView official trial listing → -
Completed NCT NCT05164523
The Effect of SGLT2 Inhibitors on Heart Rate Variability and BDNF Levels in Patients With Type 2 Diabetes
Goztepe Training and Research Hospital 64 participants Est. completion 2022-12-30 1 siteType 2 diabetes Other conditions: Heart Rate VariabilityView official trial listing → -
Completed NCT NCT05167513
Monitoring Parameters Beyond Glycemic Control: Impact of Sitagliptin on Quality of Life in Type 2 Diabetes Patients
Not yet reported Getz Pharma 188 participants Est. completion 2022-04-28 1 site Stand-aloneType 2 diabetes Other conditions: Quality of Life, Metformin+SitagliptinView official trial listing → -
Completed NCT NCT05177588
Efficacy of Metformin as add-on Therapy in Non-Diabetic Heart Failure Patients
Not yet reported Cairo University 70 participants Est. completion 2023-04-30 1 site Stand-aloneHeart failureView official trial listing → -
Status unknown NCT NCT05182970
Metformin and Prevention of Cardiovascular Events in Patients With Acute Myocardial Infarction and Prediabetes (MIMET)
Not yet reported Karolinska Institutet 5160 participants Est. completion 2026-05 1 sitePrediabetesCardiovascular diseaseView official trial listing → -
Suspended NCT NCT05183204
Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma
Not yet reported Weill Medical College of Cornell University 33 participants Est. completion 2026-06 1 site Stand-aloneOther conditions: GlioblastomaView official trial listing → -
Withdrawn NCT NCT05192850
Endometrial Cancer Recurrence in Patients Taking Metformin
WellSpan Health Est. completion 2023-02-27 1 siteOther conditions: Recurrent Endometrial CarcinomaView official trial listing → -
Status unknown NCT NCT05200793
Efficacy of Empagliflozin or Linagliptin as an Alternative to Metformin for Treatment of Polycystic Ovary Syndrome
Not yet reported Alexandria University 75 participants Est. completion 2022-09-01 1 siteOther conditions: Polycystic Ovary Syndrome (PCOS)View official trial listing → -
Status unknown NCT NCT05214235
A Clinical Study on the Effect of Hypoglycemic Drugs on the Prognosis of Spinal Surgery in Diabetic Patients
Xijing Hospital 124 participants Est. completion 2024-02-29 1 siteOther conditions: Diabetes Mellitus, Spinal DiseasesView official trial listing → -
Active, not recruiting NCT NCT05220917
Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study
Brigham and Women's Hospital 781430 participants Est. completion 2027-09-30 1 siteType 2 diabetes Other conditions: Cardiovascular Events, Renal DiseaseView official trial listing → -
Status unknown NCT NCT05226897
Clinical Trial to Assess the Efficacy and Safety of YYC405 in Type 2 Diabetes Patients
Not yet reported Yooyoung Pharmaceutical Co., Ltd. 256 participants Est. completion 2023-06-26 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05232994
Metformin and Esomeprazole For Preterm Pre-eclampsia
Not yet reported Christiana Care Health Services 38 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Preeclampsia Severe, Preeclampsia Second Trimester, Preterm Birth ComplicationView official trial listing → -
Completed NCT NCT05233514
Effect of Aerobic Exercise on Polycystic Ovary Syndrome
Not yet reported Cairo University 40 participants Est. completion 2021-12-10 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT05236530
Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir
Not yet reported Novartis Pharmaceuticals 48 participants Est. completion 2022-10-17 1 site Stand-aloneOther conditions: MalariaView official trial listing → -
Active, not recruiting NCT NCT05237960
Metformin for the Prevention of Oral Cancer in Patients With Oral Leukoplakia or Erythroplakia
Not yet reported University of Arizona 34 participants Est. completion 2026-12 10 sites Stand-aloneOther conditions: Erythroplakia, Oral LeukoplakiaView official trial listing → -
Completed NCT NCT05240274
The POWERED Study: Prophylaxis With Metformin to Prevent PTDM
Not yet reported Barts & The London NHS Trust 60 participants Est. completion 2022-08-30 1 siteOther conditions: Post-transplant Diabetes Mellitus, New Onset Diabetes After Transplant, New Onset Diabetes After Transplantation, Kidney Transplant; Complications, Renal Transplantation, End Stage Renal Disease, MetforminView official trial listing → -
Completed NCT NCT05260021
A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both
Not yet reported Eli Lilly and Company 99 participants Est. completion 2025-01-28 51 sitesType 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders, Endocrine System Diseases, Metabolic DiseaseView official trial listing → -
Status unknown NCT NCT05261997
Endotherapy for Painless Chronic Pancreatitis
Not yet reported Changhai Hospital 60 participants Est. completion 2023-11 1 siteOther conditions: Pancreatitis, Chronic, Exocrine Pancreatic Insufficiency, Abdominal Pain, Cholangiopancreatography, Endoscopic RetrogradeView official trial listing → -
Status unknown NCT NCT05262257
Evaluation and Intervention of Cognitive Function in Patients With Diabetes Mellitus.
Not yet reported The First Affiliated Hospital with Nanjing Medical University 120 participants Est. completion 2023-12-30 Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05275608
Effects of VLCKD in Metabolic Syndrome
Not yet reported Azienda Ospedaliero Universitaria Maggiore della Carita 40 participants Est. completion 2026-12 1 site Stand-aloneType 2 diabetesMetabolic syndrome Other conditions: Non-alcoholic Fatty Liver Disease, ObesityView official trial listing → -
Completed NCT NCT05279768
Stem Cells and Secretomes for Infertility Therapy in Polycystic Ovary Syndrome (PCOS) Patients With Insulin Resistance.
Not yet reported, Not yet reported PT. Prodia Stem Cell Indonesia 44 participants Est. completion 2025-01-20 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT05280496
A Pragmatic Approach to Lower Diabetes Risk After Gestational Diabetes
Not yet reported Tufts Medical Center 20 participants Est. completion 2025-04-18 1 site Stand-alonePrediabetesType 2 diabetes Other conditions: Diabetes, GestationalView official trial listing → -
Completed NCT NCT05284344
The Impact of Glucotoxicity on Gastric Emptying in Chinese Patients With Newly Diagnosed Type 2 Diabetes
University of Adelaide 78 participants Est. completion 2023-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05288153
Metformin Efficacy and Safety for Gastric Intestinal Metaplasia
Not yet reported Xijing Hospital of Digestive Diseases 140 participants Est. completion 2023-10-31 2 sites Stand-aloneOther conditions: Gastric Intestinal MetaplasiaView official trial listing → -
Status unknown NCT NCT05292573
Longitudinal Follow-up in Women With Endometrial Hyperplasia Without Atypia
Not yet reported Chang Gung Memorial Hospital 1000 participants Est. completion 2026-01-29 1 site Stand-aloneOther conditions: FemaleView official trial listing → -
Status unknown NCT NCT05296044
To Evaluate the Efficacy and Safety of JT-003 add-on in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin and Dapagliflozin
Not yet reported Jeil Pharmaceutical Co., Ltd. 245 participants Est. completion 2024-02-28 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05298670
Drug Repurposing Using Metformin for Improving the Therapeutic Outcome in Multiple Sclerosis Patients
Not yet reported German University in Cairo 80 participants Est. completion 2023-03-28 1 site Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Status unknown NCT NCT05305898
"MetCool ACS"- Metformin "Cooling" Effect on Metformin-naive Patients Treated With PCI Because of Acute Coronary Syndrome
Not yet reported Military Institute od Medicine National Research Institute 2000 participants Est. completion 2025-12 14 sites Stand-aloneOther conditions: Acute Coronary SyndromeView official trial listing → -
Active, not recruiting NCT NCT05306028
Metformin and Insulin to Pancreatic Cancer Related Diabetes (Type 3c)
Not yet reported Fudan University 20 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Pancretic Cancer, Diabete MellitusView official trial listing → -
Completed NCT NCT05313529
LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 396 participants Est. completion 2026-07-01 5 sites MixedType 2 diabetes Other conditions: Mild Cognitive ImpairmentView official trial listing → -
Active, not recruiting NCT NCT05317806
Metformin Use in Cardiac Fibrosis in PAI-1 Deficiency
Not yet reported Indiana Hemophilia &Thrombosis Center, Inc. 15 participants Est. completion 2027-10 1 site Stand-aloneOther conditions: Plasminogen Activator Inhibitor-1 Deficiency, Cardiac FibrosisView official trial listing → -
Status unknown NCT NCT05326490
Study to Evaluate the Efficacy and Safety of PB-201 in Type 2 Diabetic Mellitus Patients With Poor Glycemic Control Via Metformin Hydrochloride Monotherapy
Not yet reported PegBio Co., Ltd. 546 participants Est. completion 2024-10-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05326984
Effect of Metformin on ABCB1 and AMPK Expression in Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported Hospital General de Mexico 20 participants Est. completion 2023-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT05329857
The Study Intends to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safety Profile of Test Product Compared to Reference Product Will be Evaluated.
Not yet reported AET Laboratories Private Limited 60 participants Est. completion 2016-03 Stand-aloneOther conditions: To Determine Bioequivalence Under Fed ConditionsView official trial listing → -
Completed NCT NCT05332795
The Impact of Metformin on the Outcome of Gouty Arthritis in a Cohort of Egyptian Gouty Patients.
Not yet reported Menoufia University 100 participants Est. completion 2024-02-20 1 siteOther conditions: Gouty ArthritisView official trial listing → -
Active, not recruiting NCT NCT05333003
Semaglutide in Comorbid Schizophrenia Spectrum Disorder and Obesity
Not yet reported Centre for Addiction and Mental Health 92 participants Est. completion 2026-08 1 siteOther conditions: Schizophrenia Spectrum DisordersView official trial listing → -
Status unknown NCT NCT05333835
A Trial Comparing the Efficacy and Safety of HR17031 Injection to INS068 Injection and to SHR20004 Injection in Patients With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 455 participants Est. completion 2024-03-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05337969
The Study Aims to Show Bioequivalence of the Test Product and the Reference Reference Product in a Crossover Design Study Healthy Volunteers. Additionally, the Safety Profile of Test Product Compared to Reference Product Will be Assessed.
Not yet reported AET Laboratories Private Limited 60 participants Est. completion 2016-03 Stand-aloneOther conditions: To Determine Bioequivalence Under Fed ConditionsView official trial listing → -
Completed NCT NCT05343767
Investigate the Efficacy and Safety of Low-Glu in Patients Newly Diagnosed With Type II Diabetes Mellitus
Not yet reported Natural Wellness Egypt 198 participants Est. completion 2021-05-30 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05347459
Cognitive Protective Effect of Newer Antidiabetic Drugs
Alexandria University 100 participants Est. completion 2023-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05349474
Metformin Treatment in Progressive Multiple Sclerosis
Not yet reported University of California, Los Angeles 23 participants Est. completion 2025-05-30 1 site Stand-aloneOther conditions: Secondary Progressive Multiple Sclerosis, Primary Progressive Multiple SclerosisView official trial listing → -
Completed NCT NCT05351021
Efficacy of Metformin as Preventive Treatment in Paclitaxel Induced Peripheral Neuropathy in Breast Cancer Patients
Not yet reported Mansoura University 76 participants Est. completion 2022-10-30 1 site Stand-aloneOther conditions: Peripheral Neuropathy, Breast CancerView official trial listing → -
Completed NCT NCT05353686
A Trial Investigating the Effect of 4 Weeks Dosing of XEN-D0501 on Blood Glucose Reduction in Patients With Diabetes
Not yet reported Pila Pharma 54 participants Est. completion 2019-12-19 10 sitesType 2 diabetes Other conditions: Efficacy, Safety, PharmacokineticsView official trial listing → -
Completed NCT NCT05360147
Liraglutide Improve Cognitive Function in Patients With Type 2 Diabetes Mellitus
Not yet reported Third Military Medical University 30 participants Est. completion 2021-05-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05360537
Effects of Degludec/Liraglutide on Time in Range, Inflammation and Endothelial Function vs Insulin Basal Bolus in Diabetic Inpatients
Not yet reported University of Palermo 100 participants Est. completion 2022-04-20 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT05362799
Different Induction Protocols in PCOS After Clomiphene Citrate Failed Pregnancy in Non-IVF Cycles
Not yet reported Menoufia University 176 participants Est. completion 2023-12-31Other conditions: Infertility, FemaleView official trial listing → -
Completed NCT NCT05363384
A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 25 mg and MET XR 1,000 mg) in Healthy Volunteers
Not yet reported Celltrion 48 participants Est. completion 2022-07-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05363592
A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 12.5 mg and MET XR 500 mg) in Healthy Volunteers
Not yet reported Celltrion 48 participants Est. completion 2022-07-25 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05364164
A Food Effect Study of CT-L01 After Oral Administration in Healthy Volunteers
Not yet reported Celltrion 24 participants Est. completion 2022-07-25 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05365451
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters
Not yet reported Washington State University 16 participants Est. completion 2023-07-22 1 site Stand-aloneOther conditions: Interaction, Endogenous BiomarkersView official trial listing → -
Active, not recruiting NCT NCT05366868
Durable Effect of Imeglimin on the Glycemic Control in Patients With Type 2 Diabetes Mellitus
Not yet reported National Center for Global Health and Medicine, Japan 567 participants Est. completion 2027-03-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05367063
Canagliflozin and Myocardial Fibrosis
Not yet reported Shanghai Zhongshan Hospital 45 participants Est. completion 2025-03-20 1 siteType 2 diabetes Other conditions: Cardiovascular RiskView official trial listing → -
Completed NCT NCT05369793
Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic Neuropathy
Not yet reported Tanta University 60 participants Est. completion 2023-10-10 1 site Stand-aloneType 2 diabetes Other conditions: Diabetic NeuropathiesView official trial listing → -
Completed NCT NCT05373680
Efficacy and Safety of Metformin Versus Empagliflozin on Chronic Kidney Disease Progression
Not yet reported, Not yet reported Tanta University 118 participants Est. completion 2024-04-01 2 sites Stand-aloneOther conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT05376969
Evaluate the Long Term Safety and Efficacy of DWP16001 add-on to Metformin in Patients With T2DM Inadequately Controlled on Metformin
Not yet reported Daewoong Pharmaceutical Co. LTD. 159 participants Est. completion 2022-05-16 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05386186
The Effect of Glimepiride Compared With Sitagliptin as an add-on Therapy to Metformin in Severe Insulin Deficiency Diabetes
Not yet reported Peking University People's Hospital 192 participants Est. completion 2024-03-31 1 site Stand-aloneType 2 diabetes Other conditions: Severe Insulin Deficient DiabetesView official trial listing → -
Completed NCT NCT05386706
Treating PCOS With Digital Intervention vs. Metformin
Not yet reported Shanghai 10th People's Hospital 80 participants Est. completion 2023-09-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT05395377
Preventing Diabetes
Not yet reported Geisinger Clinic 84 participants Est. completion 2021-11-16 1 sitePrediabetesView official trial listing → -
Status unknown NCT NCT05396378
Early Recovery After Cesarean Delivery - Maternal Glucose Homeostasis Following Preoperative Glucose Dose
Women's Hospital HUS 150 participants Est. completion 2023-12-31 1 siteOther conditions: Gestational Diabetes, Cesarean Section ComplicationsView official trial listing → -
Completed NCT NCT05400863
Effect of NNS on Metformin/GDF15, Pilot
Not yet reported University of Florida 46 participants Est. completion 2024-08-02 1 site Stand-aloneOther conditions: Obesity, Adolescent, Pre DiabetesView official trial listing → -
Status unknown NCT NCT05412056
Metformin to Prevent Preterm Birth in Twin Pregnancy
Not yet reported, Not yet reported The University of Hong Kong 790 participants Est. completion 2025-06Other conditions: Preterm Birth, Premature Obstetric Labor, Twin; Complicating Pregnancy, Pregnancy Complications, Pregnancy Preterm, Metformin, Drug EffectView official trial listing → -
Completed NCT NCT05413369
iGlarLixi vs IDegAsp in Chinese Participants After OAD(s)
Not yet reported Sanofi 582 participants Est. completion 2023-10-20 60 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT05415644
Study of the Bioequivalence and Food Effects of HRX0701 Tablets in Healthy Subjects
Not yet reported Shandong Suncadia Medicine Co., Ltd. 78 participants Est. completion 2022-08-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05416580
Efficacy of Ursodeoxycholic Acid (UDCA) in Patients With Type 2 Diabetes
Not yet reported University of Banja Luka 60 participants Est. completion 2024-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05418452
Efficacy of 1% Metformin Gel Mixed With PRF in Augmenting Narrow Ridge
Not yet reported Al-Azhar University 2 participants Est. completion 2023-06-15 1 site Stand-aloneOther conditions: Horizontal Ridge DeficiencyView official trial listing → -
Status unknown NCT NCT05422092
Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 80 participants Est. completion 2023-12 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05429554
The Effect of Metformin and DPP4 Inhibitors on Cognition and Cardiovascular Protection in Type 2 Diabetic Patients
MTI University 60 participants Est. completion 2022-09 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05440591
Effects of Dapagliflozin and Metformin on Vascular Function in Newly-Diagnosed Treatment-Naive Type 2 Diabetes
Not yet reported Tan Tock Seng Hospital 150 participants Est. completion 2023-05-10 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT05451147
A Comparative Study of the Effect of Ayurvedic Drugs and Metformin in the Management of Diabetes Mellitus (Type II)
Not yet reported A & U Tibbia College Karol Bagh 48 participants Est. completion 2019-04-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05463094
GXR RM China BE Study (Darmstadt - Jiangsu)
Not yet reported Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany 84 participants Est. completion 2023-01-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT05463627
Effects of Metformin on Metabolic and Reproductive Outcomes in Chinese PCOS Patients
RenJi Hospital 1440 participants Est. completion 2023-01-01 1 siteOther conditions: Polycystic Ovary Syndrome, MetforminView official trial listing → -
Status unknown NCT NCT05468554
Evaluation of Metformin Effect on the Fertility of Women Treated With 131I for Thyroid Cancer
Not yet reported Medical University of Bialystok 160 participants Est. completion 2026-04-30 1 site Stand-aloneOther conditions: Thyroid CancerView official trial listing → -
Completed NCT NCT05478252
A Research Study to Compare Two Semaglutide Medicines in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 388 participants Est. completion 2023-09-18 104 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT05479214
Effect of Adding Metformin to Insulin in Uncontrolled Diabetic Patients During the 3rd Trimester of Pregnancy
Not yet reported Cairo University 150 participants Est. completion 2023-02-10 1 site Stand-aloneOther conditions: Diabetes Mellitus PregnancyView official trial listing → -
Completed NCT NCT05480007
Non-alcoholic Fatty Liver Disease and Its Treatment
Not yet reported Shanghai 10th People's Hospital 68 participants Est. completion 2018-12-01 Stand-aloneMASLDView official trial listing → -
Completed NCT NCT05504226
Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin 25 mg and Metformin
Not yet reported Handok Inc. 214 participants Est. completion 2024-06-18 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05504239
Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin and Metformin
Not yet reported Handok Inc. 235 participants Est. completion 2024-04-23 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05505994
The Efficacy and Safety of DWP16001 in Combination With Metformin in T2DM Patients Inadequately Controlled on Metformin
Not yet reported Daewoong Pharmaceutical Co. LTD. 340 participants Est. completion 2024-09 1 siteType 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease, Endocrine System DiseasesView official trial listing → -
Status unknown NCT NCT05507398
The Anti-tumor Effect of Metformin And Atorvastatin in Breast Cancer
Not yet reported Tanta University 100 participants Est. completion 2023-09Other conditions: Breast Cancer FemaleView official trial listing → -
Status unknown NCT NCT05513729
Effect of Canagliflozin on Liver Inflammation Damage in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver Disease
First Affiliated Hospital Xi'an Jiaotong University 80 participants Est. completion 2024-03-01 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05519813
Effects of Pioglitazone Combined With Metformin on Gonadal and Metabolic Profiles in Chinese Nonobese PCOS Patients.
Not yet reported Bing He 60 participants Est. completion 2023-03-20 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT05521633
Comparison of the Effects of Metformin and Pioglitazone on Liver Enzymes and Ultrasound Changes in Non-Diabetic Non-Alcoholic Fatty Liver
Not yet reported King Edward Medical University 96 participants Est. completion 2022-05-24 1 siteMASLDView official trial listing → -
Completed NCT NCT05526690
Study to Evaluate the Effect of CIN-107 on the Pharmacokinetics of the MATE Substrate, Metformin, in Healthy Subjects
Not yet reported AstraZeneca 27 participants Est. completion 2020-12-12 1 site Stand-aloneOther conditions: HypertensionView official trial listing → -
Terminated NCT NCT05536037
Metformin for the Prevention of Oral Cancer in Patients With Oral Premalignant Lesions
Not yet reported Thomas Jefferson University 4 participants Est. completion 2024-03-16 1 site Stand-aloneOther conditions: Erythroplakia, Leukoplakia, Oral Cavity Carcinoma, Proliferative Verrucous LeukoplakiaView official trial listing → -
Status unknown NCT NCT05536193
Topical Metformin Emulgel VS Salicylic Acid Peeling in Treatment of Acne Vulgaris
Not yet reported Assiut University 34 participants Est. completion 2023-09-10 Stand-aloneOther conditions: Acne VulgarisView official trial listing → -
Completed NCT NCT05542420
A Research Study, Looking at the Characterization of Treatment Intensified (Add on to Metformin) Real-world Adult Population With Type 2 Diabetes Mellitus in India, Pakistan and Thailand.
Novo Nordisk A/S 3000 participants Est. completion 2023-04-20 3 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT05545800
Efficacy and Safety Of Different Regimens In Patients With Type 2 Diabetes Receiving Intensive Insulin Therapy
Not yet reported Xiangya Hospital of Central South University 78 participants Est. completion 2024-06-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05549570
Comparative Bioavailability Study of Metformin/Sitagliptin 850 mg/50 mg Tablets in Healthy Male and Female Volunteers
Not yet reported Galenicum Health 26 participants Est. completion 2017-11-01 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT05549583
Comparative Bioavailability Study of Sitagliptin/Metformin 50 mg/1000 mg Tablets in Healthy Male and Female Volunteers
Not yet reported Galenicum Health 26 participants Est. completion 2018-04-25 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT05550129
Study to Evaluate the Drug-drug Interactions Between Metformin and AMG 510 in Healthy Participants
Not yet reported Amgen 13 participants Est. completion 2019-11-25 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Terminated NCT NCT05554679
Maternal and Fetal Outcome With Metformin Therapy for Obese Pregnant Women .
Not yet reported Assiut University 178 participants Est. completion 2023-07-11 1 siteOther conditions: Metformin for Obese Pregnant WomenView official trial listing → -
Completed NCT NCT05571319
A Pilot Study of Metformin to Reduce Cerebrovascular Dysfunction in Participants With HIV and Metabolic Syndrome.
Not yet reported University of Stellenbosch 30 participants Est. completion 2025-03-28 1 site Stand-aloneMetabolic syndrome Other conditions: HIV SeropositivityView official trial listing → -
Status unknown NCT NCT05572060
Effect of Metformin Use on Mortality in Diabetic and Non Diabetic Patients With Sepsis and Septic Shock.
Not yet reported Assiut University 75 participants Est. completion 2025-01-31Other conditions: Septic ShockView official trial listing → -
Completed NCT NCT05572749
Clinical Trial of Crocus Kozanis Administration in Obese Children and Adolescents
Not yet reported Aristotle University Of Thessaloniki 75 participants Est. completion 2023-09-30 1 site Stand-alonePrediabetes Other conditions: Obesity, DyslipidemiasView official trial listing → -
Withdrawn NCT NCT05580250
A Study of LY3526318 in Healthy Male Japanese Participants
Not yet reported Eli Lilly and Company Est. completion 2022-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT05580523
Aspirin Versus Metformin in Pregnancies at High Risk of Preterm Preeclampsia: a 3-arm Randomized Controlled Trial
Not yet reported Chinese University of Hong Kong 3000 participants Est. completion 2025-11-30 6 sites Stand-aloneOther conditions: PreeclampsiaView official trial listing → -
Terminated NCT NCT05590676
Metformin Treatment in Infants After Perinatal Brain Injury
Not yet reported The Hospital for Sick Children 1 participants Est. completion 2024-02-22 1 site Stand-aloneOther conditions: Hypoxic Ischemic Encephalopathy of Newborn, Premature BirthView official trial listing → -
Status unknown NCT NCT05591235
Effect of Metformin, Dapagliflozin, Combination of Metformin and Pioglitazone in Patients With Type 2 Diabetes
Not yet reported Nanjing First Hospital, Nanjing Medical University 60 participants Est. completion 2023-02Other conditions: Type2diabetes, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT05601336
of Sodium Glucose Cotransporter-2 Inhibitors on Metabolic, Hormonal and Clinical Parameters in PCO
Not yet reported Beni-Suef University 200 participants Est. completion 2023-07-30 1 siteOther conditions: PCOView official trial listing → -
Completed NCT NCT05606913
A Study of IBI362 in Participants With Type 2 Diabetes
Not yet reported Innovent Biologics (Suzhou) Co. Ltd. 731 participants Est. completion 2024-04-09 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT05607316
Evaluating the Efficacy and Safety of Metformin in Vitiligo
Not yet reported University of Massachusetts, Worcester Est. completion 2028-11-01 1 site Stand-aloneOther conditions: VitiligoView official trial listing → -
Completed NCT NCT05615012
A Study Investigating Interactions Between BMS-986322 and Rosuvastatin, Metformin and Methotrexate in Healthy Participants
Not yet reported Bristol-Myers Squibb 76 participants Est. completion 2023-12-13 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT05615467
A Study of Effect of LY3556050 on Metformin in Healthy Participants
Not yet reported Eli Lilly and Company 18 participants Est. completion 2022-12-27 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05628584
High FODMAP Diet With Metformin in preDM
Not yet reported Elaine Chow 26 participants Est. completion 2023-10-15 1 site Stand-alonePrediabetesView official trial listing → -
Status unknown NCT NCT05629806
Effect of Acarbose and Mixture of Pioglitazone and Metformin in Patients With Type 2 Diabetes
Not yet reported Nanjing First Hospital, Nanjing Medical University 50 participants Est. completion 2023-05-31 1 siteType 2 diabetes Other conditions: Blood Glucose FluctuationView official trial listing → -
Completed NCT NCT05638893
Metformin as Adjuvant Therapy in Obese Knee Osteoarthritis Patients
Not yet reported, Not yet reported Tanta University 50 participants Est. completion 2022-04-15 1 site Stand-aloneOsteoarthritisView official trial listing → -
Status unknown NCT NCT05641337
Research on Optimal Strategy of Hypoglycemic Therapy for Cirrhosis With Diabetes
Not yet reported Huashan Hospital 184 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: Liver Cirrhosis, DiabetesView official trial listing → -
Status unknown NCT NCT05646199
Semaglutide vs Metformin in Polycystic Ovary Syndrome (PCOS)
Not yet reported, Not yet reported University of Hull 60 participants Est. completion 2025-12-30 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT05653895
Independent and Additive Effects Of Micronutrients With Metformin In Patients With PCOS
Not yet reported Khyber Medical University Peshawar 120 participants Est. completion 2024-02-07 1 siteOther conditions: PCOSView official trial listing → -
Status unknown NCT NCT05655728
Treatment With Metformin in Chinese Children With Alport Syndrome
Not yet reported Peking University First Hospital 78 participants Est. completion 2025-04-20Other conditions: Alport Syndrome, MetforminView official trial listing → -
Completed NCT NCT05657613
Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects
Not yet reported CTI BioPharma 60 participants Est. completion 2023-06-08 1 site Stand-aloneOther conditions: Drug InteractionsView official trial listing → -
Status unknown NCT NCT05663736
Effect of Gemigliptin Versus Glimepiride on Cardiac Diastolic Function in Patients With Type 2 Diabetes
Not yet reported Seoul National University Bundang Hospital 80 participants Est. completion 2023-12-31 1 siteOther conditions: Ejection FractionView official trial listing → -
Completed NCT NCT05680129
A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Dulaglutide in Participants With T2DM
Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 623 participants Est. completion 2024-10-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05680662
The Study of Quadruple Therapy Quercetin, Zinc, Metformin, and EGCG as Adjuvant Therapy for Early, Metastatic Breast Cancer and Triple-negative Breast Cancer, a Novel Mechanism
Not yet reported Ministry of Health, Saudi Arabia 200 participants Est. completion 2024-01-31 Stand-aloneOther conditions: Breast Cancer Female, Triple Negative Breast CancerView official trial listing → -
Active, not recruiting NCT NCT05680805
Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 100 participants Est. completion 2025-11-30 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, MetforminView official trial listing → -
Completed NCT NCT05682495
A HR20031 BE Study on Healthy Subjects
Not yet reported Shandong Suncadia Medicine Co., Ltd. 96 participants Est. completion 2023-04-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05688332
Glycaemic & Cardiovascular Treatment Outcomes of Voglibose Vs Glibenclamide Added to Metformin in T2DM Patients
Not yet reported University of Zambia 118 participants Est. completion 2024-01 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05694221
Drug Drug Interaction (DDI) Between Supaglutide and Digoxin or Metformin
Not yet reported Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. 34 participants Est. completion 2023-08-17 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT05702905
Semaglutide Improves Metabolic Abnormalities and Fertility in Obese Infertile Women With Polycystic Ovary Syndrome
Not yet reported Peking University First Hospital 75 participants Est. completion 2025-06-30 1 site Added to GLP-1Other conditions: PCOS (Polycystic Ovary Syndrome), SemaglutideView official trial listing → -
Status unknown NCT NCT05703984
A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fasting Conditions
Not yet reported GC Biopharma Corp 50 participants Est. completion 2023-04-19 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT05708053
Cardio-protective Effect of Metformin in Patients Undergoing PCI
Not yet reported Future University in Egypt 80 participants Est. completion 2024-12 3 sites Stand-aloneOther conditions: Elective Percutaneous Coronary Intervention, Ischemic Reperfusion InjuryView official trial listing → -
Completed NCT NCT05722951
Metformin Efficacy and Safety in Epileptic Patients
Not yet reported Tanta University 60 participants Est. completion 2024-06-20 1 site Stand-aloneOther conditions: EpilepsyView official trial listing → -
Status unknown NCT NCT05729386
A Study to Evaluate the Safety, PK of GC2129A in Healthy Volunteers Under Fed Conditions
Not yet reported GC Biopharma Corp 34 participants Est. completion 2023-04-17 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT05740345
New Approaches to INOCA
Pasquale Mone 3000 participants Est. completion 2021-01-15Other conditions: New Approaches in INOCAView official trial listing → -
Completed NCT NCT05741372
A Study to Compare How Different Medicines (Rosuvastatin, Digoxin, Metformin, and Furosemide) Are Handled by the Body of Healthy People and People With Liver Cirrhosis
Not yet reported Boehringer Ingelheim 28 participants Est. completion 2024-12-30 1 site Stand-aloneOther conditions: Liver CirrhosisView official trial listing → -
Active, not recruiting NCT NCT05743387
Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural Lesotho
Not yet reported University Hospital, Basel, Switzerland 252 participants Est. completion 2027-12-31 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05743907
Clinical Trial to Evaluate the Efficacy and Safety of DA-2811 When Added to Ongoing Metformin Monotherapy in Patients with Type 2 Diabetes Who Have Inadequate Glycemic Control
Not yet reported Dong-A ST Co., Ltd. 231 participants Est. completion 2025-03-10 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT05753371
Bioequivalence Study of Metformin Hydrochloride 500 mg Film-Coated Tablets in Indonesia Healthy Subject
Not yet reported PT. Pyridam Farma Tbk 24 participants Est. completion 2022-03-31 1 site Stand-aloneOther conditions: Drug UseView official trial listing → -
Completed NCT NCT05759442
Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics
Not yet reported Bahria University 46 participants Est. completion 2023-07-15 1 sitePrediabetesView official trial listing → -
Status unknown NCT NCT05759897
A 16 Week Study of HRS-7535 in Adults With Type 2 Diabetes Mellitus
Not yet reported Shandong Suncadia Medicine Co., Ltd. 180 participants Est. completion 2024-01-04Type 2 diabetesView official trial listing → -
Status unknown NCT NCT05760456
Safety and Efficacy of DIDALA Monotherapy in Patients With Type 2 Diabetes Compared With Metformin.
Not yet reported Centre of Clinical Pharmacology, Hanoi Medical University 140 participants Est. completion 2024-08-31 2 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT05760677
Study on the Efficacy and Safety of Chiglitazar Sodium in PCOS With T2DM
Not yet reported Affiliated Hospital of Nantong University 142 participants Est. completion 2024-09-30 1 site Stand-aloneType 2 diabetes Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral OvariesView official trial listing → -
Completed NCT NCT05762471
Phase 1b/2a Study of GSBR-1290 in Adult Overweight or Obese Healthy Subjects and Subjects With Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics 142 participants Est. completion 2024-04-11 4 sitesType 2 diabetes Other conditions: Overweight or ObesityView official trial listing → -
Status unknown NCT NCT05766540
Add-on Aripiprazole on Cardiometabolic Profile in Treatment Resistant Schizophrenia: RCT
Not yet reported All India Institute of Medical Sciences, Bhubaneswar 60 participants Est. completion 2023-12-31 Stand-aloneOther conditions: Difference in the Change in Cardiovascular Risk in Treatment Resistant SchizophreniaView official trial listing → -
Completed NCT NCT05767515
The Effects of Acetyl-L-Carnitine and Myo/Chiro-Inositol in Patients With PCOS
Not yet reported Khyber Medical University Peshawar 120 participants Est. completion 2024-03-10 1 site Stand-aloneOther conditions: Infertility, Female, PCOS (Polycystic Ovary Syndrome) of Bilateral OvariesView official trial listing → -
Completed NCT NCT05768360
A Study to Assess the Effects of Savolitinib on the Pharmacokinetics of Digoxin, Rosuvastatin, Metformin, and Furosemide in Healthy Male Subjects
Not yet reported AstraZeneca 6 participants Est. completion 2023-06-24 1 site Stand-aloneOther conditions: Healthy Male SubjectsView official trial listing → -
Status unknown NCT NCT05779644
Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes Mellitus
Not yet reported RenJi Hospital 300 participants Est. completion 2025-02-23 1 site Stand-aloneType 2 diabetes Other conditions: Metformin, Obesity, Abdominal, Abdominal Fat, Non-Alcoholic Fatty Liver Disease, Metabolism Disorder, Glucose, Metabolism Disorder, LipidView official trial listing → -
Completed NCT NCT05781711
Clinical Study to Evaluate the Possible Efficacy of Metformin in Patients With Parkinson's Disease
Not yet reported Tanta University 60 participants Est. completion 2025-01-20 1 siteOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT05790577
Comparison of 30% Metformin and 2% Nicotinamide Lotion With Kligman Formula in the Treatment of Melasma
Not yet reported Ishtiaq Ahmed 88 participants Est. completion 2023-02-15 1 siteOther conditions: MelasmaView official trial listing → -
Completed NCT NCT05798715
Bioequivalence Study of of Metformin HCl From Gleptomet 50/1000 mg F.C.Tablets (EVA Pharma, Egypt) and Janumet 50/1000 mg F.C.Tablets (Merck Sharp & Dohme, The Netherlands)
Not yet reported Genuine Research Center, Egypt 30 participants Est. completion 2023-01-13 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05801627
SAL067 Treatment in Patients With Type 2 Diabetes Who Are Not Controlled by Metformin
Not yet reported Shenzhen Salubris Pharmaceuticals Co., Ltd. 408 participants Est. completion 2022-05-24 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05802212
Effect of Metformin on Patients With Polycystic Ovary Syndrome
Not yet reported Peking University Third Hospital 77 participants Est. completion 2023-05-01 1 site Stand-aloneOther conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral OvariesView official trial listing → -
Completed NCT NCT05815680
A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese Subjects
Not yet reported Innovent Biologics (Suzhou) Co. Ltd. 48 participants Est. completion 2023-10-30 1 site Stand-aloneOther conditions: Overweight Subjects, Obese SubjectsView official trial listing → -
Completed NCT NCT05816057
A Study of the Efficacy and Safety of Semaglutide Injection in the Treatment of Type 2 Diabetes Mellitus
Not yet reported Hangzhou Jiuyuan Gene Engineering Co. Ltd., 476 participants Est. completion 2023-10-31 35 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05821543
Efficacy and Safety of Sibutramin-containing Drugs in Patient With Alimentary Obesity
Not yet reported Promomed, LLC 240 participants Est. completion 2021-05-21 8 sites Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT05822674
Variable Effects of Anti-diabetics on Stress Hyperglycemia Ratio
University of Diyala 80 participants Est. completion 2023-02-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05823870
This Study is to Compare and Evaluate the Safety and Pharmacokinetic Characteristics (PK) After Administration of DW6014 and Each Component(Empagliflozin and Metformin) in Healthy Adult Volunteers in Fast Condition.
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 32 participants Est. completion 2023-03-20 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Status unknown NCT NCT05823883
This Study is to Compare and Evaluate the Safety and Pharmacokinetic Characteristics (PK) After Administration of DW6014 and Each Component in Healthy Adult Volunteers in Fed Condition.
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 30 participants Est. completion 2023-08 1 site Stand-aloneOther conditions: DW6014View official trial listing → -
Withdrawn NCT NCT05828303
A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors
Not yet reported Turning Point Therapeutics, Inc. Est. completion 2025-11-30 33 sites Stand-aloneOther conditions: Advanced Solid Tumor, Metastatic Solid TumorView official trial listing → -
Withdrawn NCT NCT05833958
Polypill Versus Metformin in New Onset Type 2 Diabetes
Not yet reported George Medicines PTY Limited Est. completion 2025-09 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05838573
Metformin Treatment on Cognitive Impairment of Schizophrenia
Not yet reported Central South University 120 participants Est. completion 2026-06-08 4 sitesOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT05840068
IGF Level in Breast Cancer Patients Treated With Metformin
Not yet reported Beni-Suef University 107 participants Est. completion 2021-07-31 1 site Stand-aloneOther conditions: Breast Cancer FemaleView official trial listing → -
Status unknown NCT NCT05847244
The Effect of Addition of Metformin In Obese Non- Diabetic Patients With Heart Failure With Preserved Ejection Fraction
Not yet reported Sara ElAdawy 80 participants Est. completion 2024-12-01 2 sites Stand-aloneOther conditions: Diastolic Dysfunction, ObesityView official trial listing → -
Status unknown NCT NCT05852639
Fetal CPR at Term for Prediction of Adverse Neonatal Outcome in Pregnancies Complicated by GDM
Cairo University 260 participants Est. completion 2024-04 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Withdrawn NCT NCT05854966
CPI-613 Given With Metformin in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Not yet reported Wake Forest University Health Sciences Est. completion 2025-09 Stand-aloneOther conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory, Granulocytic SarcomaView official trial listing → -
Completed NCT NCT05874167
A Pharmacokinetic Study of DW6013 (FDC of Linagliptin and Metformin) in Healthy Adult Volunteers
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 50 participants Est. completion 2022-10-11 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT05874180
A Pharmacokinetic Study of DW6013 (FDC of Linagliptin and Metformin) in Healthy Adult Volunteers in Fed Condition
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 31 participants Est. completion 2023-02-03 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Status unknown NCT NCT05878535
METFORMIN FOR ATRIAL FIBRILLATION
Not yet reported Arab Contractors Medical Centre 770 participants Est. completion 2025-04 1 siteOther conditions: Atrial FibrillationView official trial listing → -
Active, not recruiting NCT NCT05893225
Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration
Not yet reported University Hospital, Antwerp 120 participants Est. completion 2027-02-28 5 sitesOther conditions: Multiple Sclerosis, Primary Progressive Multiple Sclerosis, Secondary-progressive Multiple SclerosisView official trial listing → -
Status unknown NCT NCT05893849
Pharmacokinetics of Clinical Probes and Characteristics of Endogenous Biomarker in Chinese Older Adults
Peking University Third Hospital 624 participants Est. completion 2024-04 1 siteOther conditions: AgingView official trial listing → -
Completed NCT NCT05900284
Safety and Feasibility of Metformin for Sepsis Induced AKI
Not yet reported Hernando Gomez 80 participants Est. completion 2026-05-18 1 site Stand-aloneOther conditions: Sepsis, Septic Shock, Acute Kidney Injury, MetforminView official trial listing → -
Status unknown NCT NCT05902468
Ursodeoxycholic Acid as add-on Therapy in Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Tanta University 88 participants Est. completion 2024-11-28 2 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT05906563
Evaluation of Melatonin and Metformin Loaded Nanoparticles in the Treatment of Periodontal Intra-bony Defects
Not yet reported Amira ragab 52 participants Est. completion 2024-06 1 siteOther conditions: Bone Loss in JawView official trial listing → -
Withdrawn NCT NCT05910554
Investigation of the Efficacy of Metformin Therapy on Pulmonary Sarcoidosis
Not yet reported University of Maryland, Baltimore Est. completion 2027-09-01Other conditions: Sarcoidosis, PulmonaryView official trial listing → -
Completed NCT NCT05918068
Pyridoxine Effect on the Blood Glucose Level in Type 2 Diabetic Patients
Not yet reported Al-Rasheed University College 108 participants Est. completion 2023-04-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05921942
The Impact of Metformin Administration on the Clinical Outcome of Stage IV Colon Cancer
Not yet reported Ain Shams University 70 participants Est. completion 2022-12-30 1 siteOther conditions: Colorectal CancerView official trial listing → -
Suspended NCT NCT05932251
Towards Precision Medicine for Diabetes in Pregnancy
Zuyderland Medisch Centrum 103 participants Est. completion 2025-09-30 1 siteOther conditions: Gestational Diabetes, Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT05939921
Effects of Metformin Therapy on Pancreatic and Hepatic Fat Content in Patients of Type 2 Diabetes Mellitus
Not yet reported Diabetes Foundation, India 15 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: Type2diabetesView official trial listing → -
Status unknown NCT NCT05942963
Efficacy of Empagliflozin and Pioglitazone in Diabetic Patients With NAFLD
Not yet reported Jinnah Postgraduate Medical Centre 240 participants Est. completion 2024-04 1 site Stand-aloneOther conditions: Non-Alcoholic Fatty Liver Disease, Type2diabetesView official trial listing → -
Active, not recruiting NCT NCT05949008
Effect of Metformin, a Drug Used to Treat Diabetes, vs Placebo
Not yet reported University of California, Los Angeles 150 participants Est. completion 2028-07-30 1 site Stand-aloneOther conditions: NIDDM, ObesityView official trial listing → -
Status unknown NCT NCT05950516
Efficacy and Safety of Semaglutide Ingection in Subjects With Type 2 Diabetes
Not yet reported Qilu Pharmaceutical Co., Ltd. 478 participants Est. completion 2025-01-22 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT05952349
Effect of Metformin and Combination of Olive Oil Plus Nutritional Supplements on Inflammatory Markers IL-6 and IL-8 in PCOS.
Not yet reported Khyber Medical University Peshawar 88 participants Est. completion 2024-04-01 1 siteOther conditions: PCOView official trial listing → -
Not yet recruiting NCT NCT05957991
Danish Precocious Puberty Study - DAPP Study A National Cohort Study on Incidence and Etiologies for Precocious Puberty
Copenhagen University Hospital at Herlev 1500 participants Est. completion 2030-09 5 sitesOther conditions: Puberty, PrecociousView official trial listing → -
Completed NCT NCT05965219
A Trial to Evaluate the Effects of Itraconazole and Carbamazepine on the Pharmacokinetics of Emraclidine and of Emraclidine on the Pharmacokinetics of Metformin in Healthy Adult Participants
Not yet reported Cerevel Therapeutics, LLC 60 participants Est. completion 2023-11-10 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT05965908
Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome
Not yet reported Beni-Suef University 183 participants Est. completion 2025-12-30 1 siteOther conditions: Polycystic OvaryView official trial listing → -
Completed NCT NCT05966792
SGLT2 Inhibitors in Treating Patients With PCOS
Not yet reported Shanghai 10th People's Hospital 82 participants Est. completion 2025-06-30 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT05977465
Empagliflozin in Treatment of Peripheral Diabetic Neuropathy
Not yet reported, Not yet reported Tanta University 50 participants Est. completion 2023-08-03 1 site Stand-aloneOther conditions: Diabetic Neuropathy PeripheralView official trial listing → -
Status unknown NCT NCT05979038
Clinical Evaluation of the Effect of Metformin in Sepsis
Not yet reported German University in Cairo 110 participants Est. completion 2024-07-10 1 site Stand-aloneOther conditions: SepsisView official trial listing → -
Completed NCT NCT05981365
Voxelotor CYP and Transporter Cocktail Interaction Study
Not yet reported Pfizer 44 participants Est. completion 2023-10-04 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT05981742
Effects of Combined Metformin and Cabergoline in Comparison With Metformin Only Therapy on Ovarian and Hormonal Activities in Iraqi Patients With PCOS
Not yet reported Al-Rasheed University College 75 participants Est. completion 2023-03-31 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT05986838
Effect of Laser Puncture Versus Ultraviolet Radiation on Women With Polycystic Ovarian Syndrome
Not yet reported Cairo University 100 participants Est. completion 2024-04 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT05988684
Effect of Metformin on Carotid Atherosclerosis for Non-diabetic Patients With PsA (CAMPA Study)
Not yet reported Chinese University of Hong Kong 24 participants Est. completion 2025-09-30 1 site Stand-aloneOther conditions: PsA (Psoriatic Arthritis)View official trial listing → -
Completed NCT NCT05990205
Effect of the SCL16A11 Risk Haplotype on Treatments to Prevent Type 2 Diabetes
Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 437 participants Est. completion 2024-03-01 1 sitePrediabetesView official trial listing → -
Status unknown NCT NCT05994586
The Efficacy of AP029 Mix in Patients With Impaired Carbohydrate Metabolism
Not yet reported AronPharma Sp. z o. o. 30 participants Est. completion 2023-11-26 1 site Stand-alonePrediabetes Other conditions: Diabetes in AdolescenceView official trial listing → -
Completed NCT NCT05998837
GLUcose Transport and REnalPROtection in Chronic Kidney Disease
Not yet reported, Not yet reported IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy 34 participants Est. completion 2024-09-30 1 siteChronic kidney diseaseType 2 diabetes Other conditions: HypertensionView official trial listing → -
Active, not recruiting NCT NCT06000462
The Effect of Dapagliflozin on Weight Loss in Obese Adults Without Diabetes
Not yet reported Oman Ministry of Health 150 participants Est. completion 2025-12-30 1 siteOther conditions: Obesity, Dapagliflozin Adverse Reaction, Weight Loss, Effect of DrugView official trial listing → -
Active, not recruiting NCT NCT06005142
Therapeutic Intervention of Eriomin Associated with Metformin in the Control of Hyperglycemia in Pre-Diabetic Patients
Not yet reported Thais Cesar 80 participants Est. completion 2024-12-30 1 sitePrediabetesView official trial listing → -
Status unknown NCT NCT06010992
Nitazoxanide as Adjuvant Therapy in Type 2 Diabetes Mellitus
Not yet reported Tanta University 70 participants Est. completion 2025-01-01 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06012682
Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility
Not yet reported Medical University of Bialystok 200 participants Est. completion 2027-09-30 Stand-aloneOther conditions: Infertility, FemaleView official trial listing → -
Completed NCT NCT06015594
Metformin Treatment in Adolescent Patients With PCOS: A Long-term, Winning Metabolic Choice.
Not yet reported University of Cagliari 168 participants Est. completion 2022-05-01 Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT06031168
1% Metformin Gel-coated Implants and Osteointegration and Crestal Marginal Bone Loss
Not yet reported Hams Hamed Abdelrahman 26 participants Est. completion 2023-11-30 1 site Stand-aloneOther conditions: OsteointegrationView official trial listing → -
Status unknown NCT NCT06041399
The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy
Not yet reported First Affiliated Hospital of Wenzhou Medical University 1400 participants Est. completion 2025-01-02 1 site Stand-aloneOther conditions: Diabetic Peripheral NeuropathyView official trial listing → -
Completed NCT NCT06042855
ACTIV-6: COVID-19 Study of Repurposed Medications - Arm G (Metformin)
Not yet reported Susanna Naggie, MD 3214 participants Est. completion 2024-11-04 110 sites Stand-aloneOther conditions: Covid19View official trial listing → -
Completed NCT NCT06045221
A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin
Not yet reported Eli Lilly and Company 1698 participants Est. completion 2025-08-22 131 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT06049186
CRD vs. Met in Patients With Obese PCOS Infertility
Not yet reported Shanghai First Maternity and Infant Hospital 406 participants Est. completion 2026-03-31 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT06057246
Individual Determinants of Postprandial Glucose Response in Type 2 Diabetes
Not yet reported Federico II University 144 participants Est. completion 2025-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT06059287
The Effect of Henagliflozin and Metformin on Myocardial Tissue-level Characteristics
Not yet reported RenJi Hospital 64 participants Est. completion 2025-12-31Type 2 diabetes Other conditions: Obesity, Sodium-glucose Co-transporter-2 Inhibitor, Myocardial Fibrosis, Magnetic Resonance ImagingView official trial listing → -
Status unknown NCT NCT06064552
Screening For First Trimester's Hyperglycemia in High and Low Risk Pregnancy
Sohag University 100 participants Est. completion 2024-09-24 1 siteOther conditions: Screening for Hyperglycemia in First Trimester in High and Low Risk PregnancyView official trial listing → -
Completed NCT NCT06065540
A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Not yet reported Novo Nordisk A/S 2734 participants Est. completion 2026-01-06 405 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06066060
A DDI Study of JMKX000623 and Metformin Hydrochloride
Not yet reported Jemincare 24 participants Est. completion 2023-11-06 1 site Stand-aloneOther conditions: Healthy, Drug-Drug InteractionView official trial listing → -
Completed NCT NCT06068686
Vildagliptin Versus Glimepiride in Type 2 Diabetic Patients
Not yet reported Damanhour University 70 participants Est. completion 2024-12-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06071442
Potential Drug Interaction Study Between Vemircopan and Rosuvastatin, Metformin, Levonorgestrel/Ethinyl Estradiol-containing Oral Contraceptives, and Carbamazepine
Not yet reported Alexion Pharmaceuticals, Inc. 60 participants Est. completion 2024-04-12 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT06073600
Bioequivalence Study to Compare Metformin / Vildagliptin Versus Galvumet®
Not yet reported Reseach Laboratory of Clinical and Experimental Pharmacology 18 participants Est. completion 2022-11-13 1 site Stand-aloneOther conditions: Fed ConditionsView official trial listing → -
Status unknown NCT NCT06080802
The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction
Not yet reported, Not yet reported October University for Modern Sciences and Arts 80 participants Est. completion 2024-12-01 1 site Stand-aloneHeart failure Other conditions: Diabete Type 2View official trial listing → -
Withdrawn NCT NCT06083675
Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S Est. completion 2027-05-28 100 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT06083935
Evaluation of the Effects of Diosmin/Hespiridin Combination on the Clinical Outcomes in Patients With Polycystic Ovary Syndrome
Not yet reported Ain Shams University 120 participants Est. completion 2024-12-01Other conditions: Poly Cystic Ovary SyndromeView official trial listing → -
Completed NCT NCT06084156
A Study to Evaluate the DDI of HSK7653 With Metformin
Not yet reported Haisco Pharmaceutical Group Co., Ltd. 22 participants Est. completion 2019-12-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06085703
Effects of Henagliflozin on the Brain Function in T2DM Patients With Mild Cognitive Impairment: a Randomized, Parallel Controlled Clinical Trial
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 24 participants Est. completion 2025-06-30 1 site Stand-aloneType 2 diabetes Other conditions: Mild Cognitive ImpairmentView official trial listing → -
Status unknown NCT NCT06087796
Topical Pentoxifylline; Metformin Versus Betamethasone in the Treatment of Alopecia Areata.
Not yet reported Assiut University 60 participants Est. completion 2024-10 1 site Stand-aloneOther conditions: Alopecia AreataView official trial listing → -
Completed NCT NCT06092060
The Effect of a Multistrain Probiotic on Metformin Tolerance and Efficacy With Microbiota and Stool Metabolome in Insulin-resistant Women - a 12-week Randomized, Placebo-controlled, Double-blind Study
Not yet reported Poznan University of Physical Education 40 participants Est. completion 2023-07-20 1 siteOther conditions: Insulin ResistanceView official trial listing → -
Status unknown NCT NCT06096454
Effect of Life Style Modification and Metformin on Hypothyroidism With Insulin Resistance
Not yet reported Assiut University 100 participants Est. completion 2024-10-30 Stand-aloneOther conditions: Hypothyroidism, Insulin ResistanceView official trial listing → -
Terminated NCT NCT06100822
Managing Chronic Tendon Pain by Metformin
Not yet reported James Wang 21 participants Est. completion 2026-08-24 1 site Stand-aloneOther conditions: Tendinopathy, Chronic Pain, Achilles TendinopathyView official trial listing → -
Completed NCT NCT06101147
Effect of Vitamin D Supplementation on Testosterone Level in Women With Polycystic Ovary Syndrome
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 66 participants Est. completion 2024-07-30 1 site Stand-aloneOther conditions: PCOS, Vitamin DView official trial listing → -
Completed NCT NCT06103747
Bioequivalence Study to Compare Metformin / Vildagliptin (850 mg/50 mg) Versus Galvumet®
Not yet reported Reseach Laboratory of Clinical and Experimental Pharmacology 18 participants Est. completion 2023-08-15 1 site Stand-aloneOther conditions: Fed ConditionsView official trial listing → -
Completed NCT NCT06107153
Effect of Short-term Basal Insulin Initiation in Newly Diagnosed Type 2 Diabetes on 1-year Glycemic Control
Not yet reported University of Basrah 243 participants Est. completion 2024-11-01 1 siteOther conditions: Type2diabetesView official trial listing → -
Completed NCT NCT06109311
A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor
Not yet reported Eli Lilly and Company 546 participants Est. completion 2025-09-15 70 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06124495
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.
Not yet reported Galenicum Health 58 participants Est. completion 2023-02-13 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT06124547
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 50 mg /500 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.
Not yet reported Galenicum Health 48 participants Est. completion 2023-02-13 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT06124560
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.
Not yet reported Galenicum Health 58 participants Est. completion 2022-11-07 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT06124573
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fed Conditions.
Not yet reported Galenicum Health 48 participants Est. completion 2022-11-21 1 site Stand-aloneType 2 diabetes Other conditions: BioequivalenceView official trial listing → -
Completed NCT NCT06125587
Chiglitazar/Metformin in Non-obese Women With PCOS
Not yet reported, Not yet reported Shengjing Hospital 55 participants Est. completion 2024-11-20 1 siteOther conditions: Polycystic Ovary Syndrome, Chiglitazar, MetforminView official trial listing → -
Status unknown NCT NCT06126029
Effect of Metformin as Add-on Therapy to Ibuprofen on Disease Activity in Knee Osteoarthritis Patients.
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 68 participants Est. completion 2024-06-30 1 site Stand-aloneOsteoarthritis Other conditions: MetforminView official trial listing → -
Status unknown NCT NCT06127433
The Effect of Short-term Insulin Intensive Therapy Based on the Application of Insulin Pump and Real-time Dynamic Glucose Monitoring Technology on Reversing the Newly Diagnosed Type 2 Diabetes
Not yet reported Sun Yat-sen University 210 participants Est. completion 2024-12-30 1 siteOther conditions: Insulin Pump,Continuous Glucose Monitoring TechnologyView official trial listing → -
Completed NCT NCT06128967
A Multicenter, Adaptive, Randomized, doublE-blinded, Placebo-controlled Study in Participants With Long COVID-19: The REVIVE Trial
Not yet reported Cardresearch 399 participants Est. completion 2025-08-01 6 sitesOther conditions: Long COVID-19 Syndrome, Chronic Fatigue SyndromeView official trial listing → -
Not yet recruiting NCT NCT06135584
Study on MAFLD-related Cirrhosis Prevention and Treatment Strategies
Not yet reported The Affiliated Hospital of Hangzhou Normal University 1000 participants Est. completion 2026-12-31 Stand-aloneOther conditions: Metabolic Dysfunction-associated Fatty Liver Disease, CirrhosisView official trial listing → -
Status unknown NCT NCT06140485
A Trial to Investigate the Efficacy and Safety of NW Low-Glu® in Patients With Type II Diabetes Mellitus
Not yet reported Natural Wellness Egypt 400 participants Est. completion 2025-10Type 2 diabetesView official trial listing → -
Status unknown NCT NCT06141980
Study to Evaluate the Long Term Safety and Efficacy of DWP16001 in Patients With Type 2 Diabetes Mellitus
Not yet reported Daewoong Pharmaceutical Co. LTD. 134 participants Est. completion 2025-09Type 2 diabetesView official trial listing → -
Completed NCT NCT06145360
Evaluating the Efficacy and Safety of Empagliflozin Addition to Insulin and Oral Antidiabetic Medication (OAD) Regimen in Poorly Controlled Type 2 Diabetes and Obese Patient
Not yet reported SINA Health Education and Welfare Trust 150 participants Est. completion 2024-03-01 1 site Stand-aloneType 2 diabetes Other conditions: Glucose Metabolism Disorders, Hypoglycemic Agents, EmpagliflozinView official trial listing → -
Status unknown NCT NCT06147050
Effect of Metformin in Reducing Fatigue in Long COVID in Adolescents
Not yet reported Purpose Life Sciences 16 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Long COVIDView official trial listing → -
Status unknown NCT NCT06147518
To Compare the Safety and Efficacy of Dapagliflozin Plus Metformin Versus Sitagliptin Plus Metformin for Treatment of Diabetes in Patients With Compensated and Stable Decompensated Cirrhosis
Not yet reported Institute of Liver and Biliary Sciences, India 240 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Compensated Cirrhosis, Decompensated CirrhosisView official trial listing → -
Completed NCT NCT06160414
A Study to Investigate the Potential Drug Interactions Between ALXN2080 and Rosuvastatin and Metformin in Healthy Adult Participants
Not yet reported Alexion Pharmaceuticals, Inc. 20 participants Est. completion 2024-02-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT06161844
Efficacy and Safety of Semaglutide Injection (HD1916) in Patients With Type 2 Diabetes Mellitus
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 506 participants Est. completion 2025-05-14 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT06164535
The Effects of DPPIs on Cognitive Function of Diabetic Patients
Not yet reported Beni-Suef University 105 participants Est. completion 2024-07-15 1 site Stand-aloneOther conditions: Cognitive ImpairmentView official trial listing → -
Completed NCT NCT06170463
Insulin Sensitizers Role in Control of PCOS Vicious Cycle.
Not yet reported Zagazig University 210 participants Est. completion 2023-04-15 1 siteOther conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral OvariesView official trial listing → -
Status unknown NCT NCT06181422
Metformin and Lactoferrin in Sepsis in Icu
Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2024-06-09 1 siteOther conditions: SepsisView official trial listing → -
Status unknown NCT NCT06182618
Retrospective Analysis for Patients With Metabolic Syndrome
Second Affiliated Hospital, Zhejiang University, School of Medicine 400 participants Est. completion 2024-01-01 1 siteMetabolic syndromeView official trial listing → -
Status unknown NCT NCT06188234
The Prescription Patterns and Clinical Efficacy of Tenero Tab/Tenero M SR Tab
Hanlim Pharm. Co., Ltd. 3000 participants Est. completion 2026-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06192108
A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin
Not yet reported Eli Lilly and Company 962 participants Est. completion 2025-09-26 74 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT06199544
Effect of Unani Medicine for the Management of Anomalies Associated With Polycystic Ovarian Syndrome
Not yet reported Hamdard University 150 participants Est. completion 2024-12-01 1 siteOther conditions: Comparative StudyView official trial listing → -
Status unknown NCT NCT06203275
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus
Not yet reported aya ramadan ashmawy sarhan 44 participants Est. completion 2026-01Type 2 diabetesView official trial listing → -
Completed NCT NCT06204107
A Clinical Trial to Evaluate the Food Effect on Pharmacokinetic Profiles and Safety of CKD-379
Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2023-12-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06204185
Clinical and Biochemical Evaluation of 1% Metformin in Non-surgical Treatment of Periodontitis
Not yet reported Ain Shams University 40 participants Est. completion 2022-11-30 1 siteOther conditions: PeriodontitisView official trial listing → -
Status unknown NCT NCT06215976
The Nephroprotective Effect of Metformin With Cisplatin in Bladder Cancer
Not yet reported Cairo University 78 participants Est. completion 2024-12-30 1 siteOther conditions: Muscle-Invasive Bladder CarcinomaView official trial listing → -
Status unknown NCT NCT06217887
Efficacy Comparison of Polyethylene Glycol Loxenatide and Gliclazide on the Brain Function in T2DM Patients
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 58 participants Est. completion 2024-06 1 site Stand-aloneType 2 diabetes Other conditions: Cognitive Function AbnormalView official trial listing → -
Status unknown NCT NCT06218342
Henagliflozin in Relieving Type 2 Diabetes With Non-alcoholic Fatty Liver Disease
Not yet reported Sir Run Run Shaw Hospital 156 participants Est. completion 2025-12-31 Stand-aloneType 2 diabetes Other conditions: Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT06221969
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Not yet reported Novo Nordisk A/S 1024 participants Est. completion 2026-04-06 197 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06227832
A Study to Determine the Effect of KP-001 on Metformin and Midazolam Pharmacokinetics and the Effect of Clarithromycin on KP-001 Pharmacokinetics in Healthy Adult Participants
Not yet reported Kaken Pharmaceutical 38 participants Est. completion 2024-07-31 1 site Stand-aloneOther conditions: Healthy AdultsView official trial listing → -
Completed NCT NCT06229795
Effect of Green Tea on Obese Pediatrics With Prediabetes
Not yet reported Ain Shams University 90 participants Est. completion 2024-11-19 1 site Stand-alonePrediabetesView official trial listing → -
Status unknown NCT NCT06233201
Sitagliptin and Metformin Hydrochloride Tablets 50 mg/500 mg Relative to Originator
Not yet reported Bio-innova Co., Ltd 34 participants Est. completion 2024-07-28 Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Status unknown NCT NCT06233240
Sitagliptin and Metformin Hydrochloride Tablets 50 mg/1000 mg Relative to Originator
Not yet reported Bio-innova Co., Ltd 34 participants Est. completion 2024-06-12 Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT06235086
A Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes Mellitus
Not yet reported CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. 632 participants Est. completion 2026-02-03 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT06243536
The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients
Not yet reported University Hospital Sestre Milosrdnice 60 participants Est. completion 2024-12-31 1 siteType 2 diabetes Other conditions: Overweight, Disordered Eating BehaviorsView official trial listing → -
Status unknown NCT NCT06244407
The Bioequivalence Study of Fixed-dose Combination of Vildagliptin and Metformin HCI 50/1000 mg FCT Under Fed Conditions
Not yet reported International Bio service 40 participants Est. completion 2024-06-02 Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Completed NCT NCT06244550
Clinical Trials Using HepatoKeeper Herbal Essentials to Treat Non-alcoholic Fatty Liver Disease and Metabolic Factors
Not yet reported Taipei City Hospital 60 participants Est. completion 2023-06-13 1 site Stand-aloneOther conditions: Non-alcoholic Fatty Liver Disease, Liver Fibrosis, Liver InjuryView official trial listing → -
Completed NCT NCT06247748
Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects
Not yet reported Beijing Dongfang Biotech Co., Ltd. 28 participants Est. completion 2024-04-15 1 siteType 2 diabetes Other conditions: OverweightView official trial listing → -
Status unknown NCT NCT06248801
Vildagliptin and Metformin Tablets 50/1000 mg Relative to GALVUS MET (50mg/1000 mg) Tablets
Not yet reported Bio-innova Co., Ltd 48 participants Est. completion 2024-10-15 Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Status unknown NCT NCT06252194
Comparative Study of Metformin Versus Doxycycline in Moderate to Severe Adult Acne Vulgaris Patients.
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 120 participants Est. completion 2024-03 1 site Stand-aloneOther conditions: Acne VulgarisView official trial listing → -
Status unknown NCT NCT06256289
Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome
Not yet reported Ping Li,MD 50 participants Est. completion 2025-04-30 Stand-aloneOther conditions: Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Active, not recruiting NCT NCT06257966
A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Dulaglutide in Combination Therapy Diabetes Mellitus Type 2 Patients With Metformin
Not yet reported Beijing Dongfang Biotech Co., Ltd. 600 participants Est. completion 2026-11-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06260722
Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)
Not yet reported Eli Lilly and Company 1250 participants Est. completion 2027-02 77 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06266598
Effectiveness of Antidiabetic Treatment Applied in Childhood Obesity
Not yet reported HÜMEYRA ACIKAN 52 participants Est. completion 2021-10-27 1 siteOther conditions: Childhood Obesity, Insulin ResistanceView official trial listing → -
Completed NCT NCT06280274
Metformin Use in Patients Undergoing Total Joint Replacement Surgery
Not yet reported Oregon Health and Science University 40 participants Est. completion 2025-09-15 1 site Stand-aloneOther conditions: HyperglycemiaView official trial listing → -
Terminated NCT NCT06296836
Effect of Continuing Versus Holding Metformin During Hospitalizations.
Not yet reported University of Illinois at Chicago 22 participants Est. completion 2026-04-30 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06297603
Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)
Not yet reported Eli Lilly and Company 320 participants Est. completion 2026-11 76 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06323161
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without Metformin
Not yet reported Novo Nordisk A/S 274 participants Est. completion 2025-10-23 61 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT06325956
PCOS Immune Function Predicts Metformin Efficacy
Not yet reported Shanghai 10th People's Hospital 100 participants Est. completion 2026-07-01 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Metformin, Immune FunctionView official trial listing → -
Completed NCT NCT06326840
Clinical Efficacy and Adverse Reactions of Antipsychotic Treatment
Not yet reported Taipei Medical University Hospital 42 participants Est. completion 2011-06-10 1 site Stand-aloneOther conditions: Metabolic Disturbance, Hyperprolactinemia, SchizophreniaView official trial listing → -
Completed NCT NCT06327191
EMERGE Mothers and Kids
National University of Ireland, Galway, Ireland 370 participants Est. completion 2026-04-02 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT06327815
Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM
Not yet reported AstraZeneca 633 participants Est. completion 2025-06-30 35 sites Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06328426
Vitamin D With Omega-3 or Metformin in Osteoarthritis
Not yet reported Assiut University 60 participants Est. completion 2026-12OsteoarthritisView official trial listing → -
Completed NCT NCT06332612
Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial
Not yet reported, Not yet reported Ziauddin University 30 participants Est. completion 2025-01-06 1 site Stand-aloneOther conditions: Oral Submucous FibrosisView official trial listing → -
Terminated NCT NCT06333080
The Effect of Adherence to Oral Semaglutide on Glycaemic Control in People With Type 2 Diabetes Treated With Metformin
Aalborg University Hospital 1 participants Est. completion 2025-07-29 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06335134
A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin
Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 57 participants Est. completion 2024-06-28 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT06339086
Efficacy and Safety of Semaglutide Injection in Subjects With Type 2 Diabetes
Not yet reported Chengdu Brilliant Pharmaceutical Co., Ltd. 478 participants Est. completion 2025-12-30 Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT06353061
Chemoradiotherapy With or Without Metformin in Locally Advanced Cervical Cancer
Not yet reported Peking Union Medical College Hospital 51 participants Est. completion 2026-02-01 1 site Stand-aloneOther conditions: Cervical Cancer, Radiotherapy, Metformin, Hypoxia, PET/CTView official trial listing → -
Completed NCT NCT06353347
Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin
Not yet reported Shenzhen HighTide Biopharmaceutical Ltd. 551 participants Est. completion 2025-07-30 64 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06357273
The Effect of White Tea Consumption on Obesity
Recep Tayyip Erdogan University 91 participants Est. completion 2023-12-15 1 siteOther conditions: Obesity, Obesity; Endocrine, Obesity Adult OnsetView official trial listing → -
Terminated NCT NCT06359015
Metformin and Esomeprazole in Preterm Pre-eclampsia
Not yet reported Christiana Care Health Services 4 participants Est. completion 2025-05-08 1 site Stand-aloneOther conditions: Preeclampsia Severe, Pre-Eclampsia, Preeclampsia, Preeclampsia Second Trimester, Preeclampsia Complicating Childbirth, Preeclampsia Puerperium, PretermView official trial listing → -
Completed NCT NCT06370247
First-time Usage of SGLT2 Inhibitors in Type 2 Diabetic Patients Who Are Fasting During Ramadan: Safety and Efficacy
Not yet reported Sohag University 60 participants Est. completion 2023-09-25 1 siteType 2 diabetes Other conditions: SGLT2 Inhibitors, First Time Use, Fasting in RamadanView official trial listing → -
Completed NCT NCT06393348
Efficacy and Safety of HRS-7535 Tablets in T2DM Subjects Poorly Controlled With Metformin and SGLT2i.
Not yet reported Shandong Suncadia Medicine Co., Ltd. 155 participants Est. completion 2025-03-13 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06405178
Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome
Not yet reported Beni-Suef University 200 participants Est. completion 2026-04-01 1 site Stand-aloneOther conditions: Polycystic OvaryView official trial listing → -
Status unknown NCT NCT06405971
Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE)
Not yet reported Ming Lv 60 participants Est. completion 2025-06-01 1 site Stand-aloneOther conditions: Dissecting Aneurysm of Cerebral ArteryView official trial listing → -
Completed NCT NCT06415773
Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin
Not yet reported Shenzhen HighTide Biopharmaceutical Ltd. 367 participants Est. completion 2025-07-25 53 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06416800
A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants
Not yet reported Incyte Corporation 71 participants Est. completion 2025-01-15 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Not yet recruiting NCT NCT06417489
Evaluation of Efficacy and Safety of Combination Therapy of Henagliflozin Proline, Retagliptin and Metformin in New Diagnosed Type 2 Diabetes Patients
Not yet reported Peking University First Hospital 160 participants Est. completion 2026-12-31 Stand-aloneType 2 diabetesView official trial listing → -
Enrolling by invitation NCT NCT06429007
A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury
Not yet reported Boston Children's Hospital 30 participants Est. completion 2029-03-01 1 site Stand-aloneOther conditions: Hypoxic-Ischemic Encephalopathy, HIE, Neurodevelopment, Infant DevelopmentView official trial listing → -
Status unknown NCT NCT06430125
Nephroprotective Effect of Nicorandil in Type 2 Diabetes Mellitus
Not yet reported Tanta University 46 participants Est. completion 2025-02 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT06439758
Effects of First-Line Oral Hypoglycemics in Bone Markers of Treatment Naïve Saudi Adults With Type 2 Diabetes
Not yet reported King Saud University 111 participants Est. completion 2025-12-01 Stand-aloneOther conditions: Diabetes Type 2, OsteoporosisView official trial listing → -
Status unknown NCT NCT06449235
Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh
Not yet reported Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders 938 participants Est. completion 2025-06 1 siteOther conditions: Type2diabetesView official trial listing → -
Completed NCT NCT06450262
Bioequivalence Study to Compare Empagliflozin/ Metformin HCl 12.5mg/1000mg Film-coated Tablets
Not yet reported Humanis Saglık Anonim Sirketi 36 participants Est. completion 2024-03-05 1 site Stand-aloneOther conditions: Type2diabetesView official trial listing → -
Completed NCT NCT06452017
Effects of Telerehabilitation Exercise Program on Maternal Glycemic Control
Not yet reported Riphah International University 70 participants Est. completion 2025-05-30 2 sitesOther conditions: Gestational Diabetes Mellitus in PregnancyView official trial listing → -
Not yet recruiting NCT NCT06452498
Preeclampsia Intervention Netherlands
Not yet reported Amsterdam UMC 180 participants Est. completion 2028-07 Stand-aloneOther conditions: Pre-Eclampsia Onset Less Than 37 Weeks, Pre-Eclampsia, Pre-Eclampsia; Complicating Pregnancy, Pre-Eclampsia as Antepartum Condition, Pre-eclampsia or Eclampsia With Pre-existing Hypertension, Pre-Eclampsia; Affecting Fetus, HELLP Syndrome Complicating Pregnancy, HELLP Syndrome, HELLPView official trial listing → -
Completed NCT NCT06452511
Comparing the Effect of Metformin vs. Pep2dia as an Adjunct to Letrozole on Ovulation Induction and Pregnancy Outcomes in Overweight Women With PCOS
Not yet reported Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy 100 participants Est. completion 2025-03-25 1 siteOther conditions: PCOSView official trial listing → -
Not yet recruiting NCT NCT06460896
Analysis of the Influence of Gastric By-Pass on the Pharmacokinetics of Common Drugs
Not yet reported Assistance Publique - Hôpitaux de Paris 64 participants Est. completion 2027-09 1 siteOther conditions: Bypass Bariatric SurgeryView official trial listing → -
Completed NCT NCT06473662
Study to Evaluate the Safety and Efficacy of Oral Insulin Formulation in Type 2 Diabetes Mellitus Subjects
Not yet reported Roger New 153 participants Est. completion 2020-07-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06475586
Effect of Semaglutide on the Psoriatic Lesions in Patients With Type 2 Diabetes Mellitus
Not yet reported University of Banja Luka 30 participants Est. completion 2024-06-10 1 siteOther conditions: Psoriasis Vulgaris, Diabetes Type 2View official trial listing → -
Completed NCT NCT06476730
Telerehabilitation Exercise: Effects on Maternal Psychological Health and Delivery Outcomes
Not yet reported Riphah International University 62 participants Est. completion 2025-05-10 2 sitesOther conditions: Gestational Diabetes Mellitus in Pregnancy, Gestational Diabetes, Maternal Psychological DistressView official trial listing → -
Completed NCT NCT06479434
Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls
Not yet reported Aga Khan University 110 participants Est. completion 2025-10-02 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Insulin ResistanceView official trial listing → -
Completed NCT NCT06480292
Telerehabilitation Exercise: Effects on Maternal Quality of Life, Fetal and Neonatal Health.
Not yet reported Riphah International University 68 participants Est. completion 2025-06-10 2 sitesOther conditions: Gestational Diabetes Mellitus in PregnancyView official trial listing → -
Completed NCT NCT06481085
To Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 324 participants Est. completion 2025-06-30 31 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06483243
Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetic of CKD-501, D745, and D150 for Healthy Subjects in Fed State.
Not yet reported Chong Kun Dang Pharmaceutical 45 participants Est. completion 2024-05-17 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT06490874
Continuous Glucose Monitoring (CGM) Substudy of the DECIDE RCT
Ohio State University Est. completion 2030-12 4 sitesOther conditions: Gestational Diabetes Mellitus, Pregnancy, High RiskView official trial listing → -
Status unknown NCT NCT06492655
To Evaluate the Food Effect on Pharmacokinetic Profiles and Safety in Healthy Volunteers
Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2024-08-08Type 2 diabetesView official trial listing → -
Completed NCT NCT06495281
Observational Study of Triple Combination Therapy of Zemidapa Tab. and Metformin in Type 2 Diabetes Mellitus Patients
LG Chem 2044 participants Est. completion 2025-12-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06495931
Study on Drug Interaction of HRS-1780 Tablets, Henagliflozin Tablets, Metformin Tablets and HRS-7535 Tablets in Healthy Human
Not yet reported Shandong Suncadia Medicine Co., Ltd. 24 participants Est. completion 2024-08-13 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06504862
A Study in Healthy Men to Test Whether Zongertinib Influences the Amount of 4 Other Medicines (Dabigatran, Rosuvastatin, Metformin, and Furosemide) in the Blood
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2024-12-18 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT06515652
To Compare the Effects of Herbal Medicines With Traditional Allopathic Medicines in Cases of Patients With Metabolic Syndrome
Not yet reported Hamdard University 200 participants Est. completion 2024-08-30 1 siteMetabolic syndromeView official trial listing → -
Status unknown NCT NCT06519786
Safety and Efficacy of Metformin for Treatment of Cytopenia in Children and Adolescents With Fanconi Anemia
Not yet reported Ain Shams University 30 participants Est. completion 2025-03 2 sites Stand-aloneOther conditions: Fanconi AnemiaView official trial listing → -
Completed NCT NCT06523595
Evaluation of the Pharmacokinetic Drug-drug Interactions Between VX-993 and Metformin in Healthy Adults
Not yet reported Vertex Pharmaceuticals Incorporated 31 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: PainView official trial listing → -
Withdrawn NCT NCT06526494
Metformin and Vascular Function in Prediabetes
Not yet reported Diana Jalal Est. completion 2025-12-01 2 sites Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT06528002
Hybrid Method Between Low-ratio Premixed Insulin and Short Acting Insulin in Fasting Type 2 Diabetic Patients in Ramadan
Sohag University 45 participants Est. completion 2024-06-15 1 siteOther conditions: Continous Blood Glucose Monitoring, Calculation of Body Mass Index, Measurment of Blood PressureView official trial listing → -
Status unknown NCT NCT06545526
Chemopreventive Effect of Combination of Celecoxib and Metformin in Patients With Familial Adenomatous Polyposis
Not yet reported Yonsei University 28 participants Est. completion 2026-06-30 1 site Stand-aloneOther conditions: Familial Adenomatous PolyposisView official trial listing → -
Status unknown NCT NCT06545994
A Prospective Cohort Study on the Serum Kisspeptin Levels Throughout Pregnancy in PCOS
Fudan University 180 participants Est. completion 2026-06-30 1 siteOther conditions: Polycystic Ovary Syndrome, Pregnancy ComplicationsView official trial listing → -
Status unknown NCT NCT06559722
A Trial Investigating the Efficacy and Safety of Insulin Degludec/Liraglutide Injection in Subjects With Type 2 Diabetes
Not yet reported Tonghua Dongbao Pharmaceutical Co.,Ltd 510 participants Est. completion 2026-02 Added to GLP-1Type 2 diabetesView official trial listing → -
Withdrawn NCT NCT06560333
iSGLT2 Inhibitor and a iDPP -4 Inhibitor in Treatment of Type 2 Diabetes Mellitus in Patients Treated With Metformin (TRIAD)
Not yet reported Eurofarma Laboratorios S.A. Est. completion 2029-02-28 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT06570980
Comparative Analysis of Cost-effectiveness Between Sulfonylureas and DPP4 Inhibitors in Combination With Metformin in Treatment of Type 2 Diabetic Patients : A Retrospective, Observational Study.
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 200 participants Est. completion 2024-08-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06571591
Efficacy and Safety of Pioglitazone Combination Therapy in Type 2 Diabetes Patients on a Background of Empagliflozin With Metformin
Not yet reported Celltrion 606 participants Est. completion 2026-05-04 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT06576375
Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome
Not yet reported Future University in Egypt 70 participants Est. completion 2025-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT06589141
Comparison Between Metformin and Glyburide in the Management of Gestational Diabetes
Not yet reported Assiut University 180 participants Est. completion 2026-06-30 Stand-aloneOther conditions: Gestational Diabetes Mellitus in PregnancyView official trial listing → -
Completed NCT NCT06589765
A Study of HRS-7535 Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequately Controlled With Metformin
Not yet reported Shandong Suncadia Medicine Co., Ltd. 810 participants Est. completion 2026-05-29 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06603480
Effects of Exercise and Metformin on Methylglyoxal Levels in Prediabetic Individuals
Not yet reported Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey 96 participants Est. completion 2022-12-07 1 site Stand-alonePrediabetes Other conditions: Methylglyoxal, Exercise, MetforminView official trial listing → -
Completed NCT NCT06605703
A Randomized Controlled Trial Comparing the Effectiveness of Different Treatment Options for Weight Management After Discontinuation of Semaglutide and Tirzepatide (GLP1 Transition Trial)
Not yet reported WW International Inc 226 participants Est. completion 2026-02-05 1 site Stand-aloneOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT06606886
Effects of Hydroxyurea and Metformin in Transfusion Dependent Beta-Thalassemia
Not yet reported Bahria University 96 participants Est. completion 2026-02-09 1 siteOther conditions: Transfusion Dependent Beta-thalassemiaView official trial listing → -
Active, not recruiting NCT NCT06611501
Glycemic Regulation as Endometriosis Adjunct Treatment
Not yet reported Boston Children's Hospital 14 participants Est. completion 2027-01 1 site Stand-aloneOther conditions: Pelvic Pain, EndometriosisView official trial listing → -
Status unknown NCT NCT06611904
The Effect of Combined Dulaglutide and Dapagliflozin Treatment vs DPP-4 Inhibitors in Endothelial and Vascular Function in Patients With Type 2 Diabetes Mellitus and Albuminuria
Not yet reported Attikon Hospital 60 participants Est. completion 2024-12-15 1 siteOther conditions: Urine Albumin (UAlb), Glycocalyx, Arterial StiffnessView official trial listing → -
Completed NCT NCT06613750
Comparative Study of Sitagliptin and Gliclazide With Metformin in Type 2 Diabetes Patients With Glucotoxicity
Not yet reported Zhibin Xu 129 participants Est. completion 2024-07-01 1 siteType 2 diabetes Other conditions: GlucotoxicityView official trial listing → -
Completed NCT NCT06628544
Trained Immunity in Fungal Infection and Its Mechanism
Not yet reported Zhongnan Hospital 79 participants Est. completion 2023-12-01 1 site Stand-aloneOther conditions: BCG VaccinationView official trial listing → -
Completed NCT NCT06638671
Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity
Not yet reported University of Virginia 14 participants Est. completion 2026-03-12 1 site Stand-aloneOther conditions: Exercise Capacity, MetforminView official trial listing → -
Not yet recruiting NCT NCT06644404
Phase 1 Study of Drug-Drug Interactions Between DWP16001, DWC202407, and DWC202408 in Healthy Adults
Not yet reported Daewoong Pharmaceutical Co. LTD. 34 participants Est. completion 2025-04-01 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT06649344
A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 Diabetes
Not yet reported Fujian Shengdi Pharmaceutical Co., Ltd. 884 participants Est. completion 2026-07-18 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06649773
The Experiment of Noiiglutide Injection in Type 2 Diabetes Patients
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 137 participants Est. completion 2025-12-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06654960
Influence of HRS9531 on Pharmacokinetics of Metformin in Healthy Subjects
Not yet reported Fujian Shengdi Pharmaceutical Co., Ltd. 20 participants Est. completion 2024-12-26 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06655220
A Study in Healthy Men to Test Whether BI 1815368 Influences the Amount of Metformin in the Body
Not yet reported Boehringer Ingelheim 14 participants Est. completion 2025-01-13 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Enrolling by invitation NCT NCT06666933
Study of Time-restricted Eating (TRE) to Clinical Pregnancy Rate in PCOS Women With Glucose Metabolism Disorder Via IVF/ICSI
Not yet reported RenJi Hospital 254 participants Est. completion 2026-07 1 site Stand-aloneOther conditions: PCOS, Glucose Metabolism Disorder, IVF OutcomeView official trial listing → -
Not yet recruiting NCT NCT06670209
A Phase I Clinical Study to Evaluate the Effect of GZR18 Injection on the Pharmacokinetics of Oral Metformin Hydrochloride Tablets in Overweight/Obese Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 32 participants Est. completion 2025-03-19 Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06675994
In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme
LifeBridge Health 80 participants Est. completion 2025-12-30PrediabetesCardiovascular disease Other conditions: Healthy, Hypercholesterolemia, Hypertension, Overweight, Diabetes, Family History of Peripheral Artery Disease, Family History of Cerebrovascular DiseaseView official trial listing → -
Completed NCT NCT06679413
A Study to Assess Drug-drug Interaction of ZX008 in Healthy Male and Female Study Participants
Not yet reported UCB BIOSCIENCES, Inc. 22 participants Est. completion 2025-06-12 1 site Stand-aloneOther conditions: Healthy Study ParticipantsView official trial listing → -
Not yet recruiting NCT NCT06682351
Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention
Not yet reported Stanford University 200 participants Est. completion 2027-12 1 site Stand-aloneType 2 diabetesPrediabetesView official trial listing → -
Enrolling by invitation NCT NCT06683235
Effect of Flaxseed as a Treatment for Adults With Type 2 Diabetes Mellitus in Mexico
Not yet reported Universidad Autónoma Benito Juárez de Oaxaca 160 participants Est. completion 2025-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06688123
Efficacy and Safety of SHR-3167 and Insulin Glargine in Type 2 Diabetes Subjects
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 275 participants Est. completion 2026-04-22 2 sitesType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06691542
Efficacy and Safety of Platelet-rich Plasma, Metformin and Cryotherapy in Treatment of Non-genital Warts
Not yet reported, Not yet reported Assiut University 108 participants Est. completion 2025-04 Stand-aloneOther conditions: Non-Genital WartsView official trial listing → -
Not yet recruiting NCT NCT06713967
Comparison of Pregnancy Outcomes in Women with Polycystic Ovarian Syndrome with and Without Glucophage
Not yet reported University of Health Sciences Lahore 70 participants Est. completion 2025-05-26 Stand-aloneOther conditions: Polycystic Ovarian Syndrome (PCOS), Pregnancy OutcomesView official trial listing → -
Not yet recruiting NCT NCT06717087
Study of Acupuncture to Control Weight and Improve Pregnancy Rates in Overweight/Obese PCOS Patients
Not yet reported RenJi Hospital 92 participants Est. completion 2026-06-01 1 siteOther conditions: Polycystic Ovary Syndrome, Metformin, AcupunctureView official trial listing → -
Completed NCT NCT06727838
Study on Drug Interaction of Metformin Tablets and HRS-7535 Tablets in Healthy Human
Not yet reported Shandong Suncadia Medicine Co., Ltd. 18 participants Est. completion 2025-01-25 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT06728982
Impact Of Metformin In Rectal Cancer Patients
Not yet reported, Not yet reported Minia University 85 participants Est. completion 2025-07-15 2 sitesOther conditions: Rectal Cancer PatientsView official trial listing → -
Completed NCT NCT06739044
Efficacy and Safety of Semaglutide Injection vs Ozempic® in Patients With Type 2 Diabetes
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 494 participants Est. completion 2025-02-21 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06743698
META Trial - a Mixed Methods Process Evaluation
University College Dublin 60 participants Est. completion 2027-02Prediabetes Other conditions: HIVView official trial listing → -
Completed NCT NCT06759922
Glimepiride, Empagliflozin, and Sitagliptin With Metformin for Type 2 Diabetes
Not yet reported Bahria University 172 participants Est. completion 2025-06-30 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06762041
Effects of Metformin on Androgens and Other Steroid Hormones in Affected Subjects With Autism
Insel Gruppe AG, University Hospital Bern 20 participants Est. completion 2026-11-30Other conditions: AutismView official trial listing → -
Not yet recruiting NCT NCT06762223
Henagliflozin on Liver Fibrosis in Patients with MASLD and T2DM
Not yet reported Xiqiao Zhou 190 participants Est. completion 2026-12-31 1 site Stand-aloneMASLDType 2 diabetesView official trial listing → -
Completed NCT NCT06766201
Effect of Use of Calcium Hydroxide and Metformin Intracanal Medicament After NSRCT
Not yet reported, Not yet reported Postgraduate Institute of Dental Sciences Rohtak 120 participants Est. completion 2025-01-01 1 site Stand-aloneOther conditions: Apical PeriodontitisView official trial listing → -
Completed NCT NCT06766500
Pharmacokinetics and Bioequivalence Study of Empagliflozin+Metformin Hydrochloride 5 mg/850 mg Film-coated Tablets (Gedeon Richter Plc., Hungary) Versus Synjardy® 5 mg/850 mg Film-coated Tablets (Boehringer Ingelheim International GmbH, Germany)
Not yet reported Gedeon Richter Plc. 64 participants Est. completion 2025-02-28 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06772857
Aerobic Versus Resistance Exercises on Insulin Sensitivity in Obese Patients
Not yet reported Cairo University 3 participants Est. completion 2025-01-30 1 site Stand-aloneOther conditions: Insulin Sensitivity/ResistanceView official trial listing → -
Enrolling by invitation NCT NCT06773923
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
Not yet reported Universidad Austral de Chile 10 participants Est. completion 2025-12-01 1 siteOther conditions: Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures, Bone Loss, Age RelatedView official trial listing → -
Not yet recruiting NCT NCT06775093
Effects of GLP-1RAs on Reproductive Outcomes in PCOS and Obesity
Not yet reported Peking University Third Hospital 392 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Obesity, Infertility, FemaleView official trial listing → -
Active, not recruiting NCT NCT06778967
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus
Not yet reported Gan & Lee Pharmaceuticals. 1100 participants Est. completion 2026-12-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06779253
A Study to Investigate The Effect of Pimicotinib on The Pharmacokinetics of Metformin, Fexofenadine and Rosuvastatin In Healthy Subjects
Not yet reported Abbisko Therapeutics Co, Ltd 39 participants Est. completion 2025-05-22 1 siteOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT06792968
Pharmacokinetics and Bioequivalence Study of Empagliflozin+Metformin Hydrochloride 5 mg/1000 mg Film-coated Tablets (Gedeon Richter Plc., Hungary) Versus Synjardy 5 mg/1000 mg Film-coated Tablets (Boehringer Ingelheim International GmbH, Germany)
Not yet reported Gedeon Richter Plc. 64 participants Est. completion 2025-04-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06793943
A Study of Interaction of Zasocitinib (TAK-279) With Other Medicines in Healthy Adults
Not yet reported Takeda 78 participants Est. completion 2025-03-30 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Enrolling by invitation NCT NCT06804187
Sweet Sensing in Type 2 Diabetes
University of Nottingham 505 participants Est. completion 2026-06 1 siteType 2 diabetesPrediabetesView official trial listing → -
Completed NCT NCT06812585
The Effect of Metformin As an Adjuvant Therapy on Immunological Parameters in Egyptian Patients with RRMS: a Pilot Study
Not yet reported German University in Cairo 30 participants Est. completion 2025-01-30 1 site Stand-aloneOther conditions: Multiple Sclerosis (MS) - Relapsing-remittingView official trial listing → -
Completed NCT NCT06813924
A Research Study of the Effect of Etavopivat on Other Drugs in Healthy Participants
Not yet reported Novo Nordisk A/S 37 participants Est. completion 2025-05-27 1 site Stand-aloneOther conditions: Healthy Volunteers Sickle Cell Disease, ThalassemiaView official trial listing → -
Completed NCT NCT06823856
Pharmacokinetics and Bioequivalence Study of Empagliflozin+Metformin Hydrochloride 12.5 mg/1000 mg Film-coated Tablets (Gedeon Richter Plc., Hungary) Versus Synjardy 12.5 mg/1000 mg Film-coated Tablets (Boehringer Ingelheim International GmbH, Germany)
Not yet reported Gedeon Richter Plc. 64 participants Est. completion 2025-05-21 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06840613
Glucophage Plus Myo-Inositol vs Glucophage in Glycemic Control Among Patients With Gestational Diabetes Mellitus
Not yet reported University of Health Sciences Lahore 90 participants Est. completion 2025-05Other conditions: Gestational Diabetes Mellitus (GDM)View official trial listing → -
Enrolling by invitation NCT NCT06846138
Enhancing the Efficacy and Tolerability of Metformin by add-on Polyherbal Formulation: a Gut Microbiome Study
Not yet reported Pauls Stradins Clinical University Hospital 66 participants Est. completion 2026-12-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06851962
Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.
Not yet reported Fundación para la Investigación del Hospital Clínico de Valencia 92 participants Est. completion 2026-06-30 3 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06856369
Clinical Efficacy of 1% Metformin and Alendronate Gel in Adjunct to Fibrin in Chronic Periodontitis
Not yet reported Bahria University 120 participants Est. completion 2027-09-30 1 siteOther conditions: Alveolar Bone Loss Associated Chronic PeriodontitisView official trial listing → -
Active, not recruiting NCT NCT06860841
Effects of D-Chiro-Inositol Combined with Metformin on Insulin Resistance in People with Overweight or Obesity and T2DM
Not yet reported Campus Bio-Medico University 16 participants Est. completion 2025-04-10 1 site Stand-aloneType 2 diabetes Other conditions: Overweight and Obese AdultsView official trial listing → -
Completed NCT NCT06871761
A Trial Comparing HR17031 With Insulin Glargine in Patients With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 393 participants Est. completion 2025-05-13 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06871904
Fibrosis-Modulating Effects of Metformin and Pirfenidone in Oral Submucous Fibrosis
Not yet reported, Not yet reported Ziauddin University 45 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: Oral Submucous FibrosisView official trial listing → -
Completed NCT NCT06881264
A Study Comparing HR17031 With Insulin Glargine in Patients With Type 2 Diabetes
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 401 participants Est. completion 2025-09-19 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06882291
Intermittent Fasting Diet Versus Resistive Exercise Program on Insulin Resistance in Obese Women With P.C.O.S
Not yet reported Cairo University 72 participants Est. completion 2025-09-30 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Terminated NCT NCT06884683
Nivolumab Plus Metformin in Metastatic Renal Cell Carcinoma
Not yet reported Fondazione Policlinico Universitario Agostino Gemelli IRCCS 12 participants Est. completion 2023-09-13 2 sites Stand-aloneOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Not yet recruiting NCT NCT06893978
Placental Organoids Development: Application in the Study of the Human Reproduction Pathophysiology.
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 20 participants Est. completion 2027-11 1 siteOther conditions: Preeclampsia, Pregnancy Loss, Preterm Birth, HealthyView official trial listing → -
Active, not recruiting NCT NCT06899061
Modular Clinical Pharmacology Study to Evaluate the Drug-drug Interaction Potential and Relative Bioavailability of Saruparib
Not yet reported AstraZeneca 41 participants Est. completion 2028-05-19 4 sitesOther conditions: Advanced Solid MalignanciesView official trial listing → -
Active, not recruiting NCT NCT06907472
Diabetes Management for Primary Healthcare Centers.
Not yet reported University of Abuja 106 participants Est. completion 2026-12-31 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06911983
Comparative Efficacy of Metformin and Berberine Among TCF7L2 (rs7903146) TT vs. CC Genotype Carriers With Type 2 Diabetes
Not yet reported S.LAB (SOLOWAYS) 60 participants Est. completion 2026-03-01 1 siteOther conditions: Diabetes MellitisView official trial listing → -
Completed NCT NCT06913881
Comparative Cardiovascular Effectiveness of GLP-1 RAs vs. Insulin in Early-Onset Type 2 Diabetes
Karolinska Institutet 92100 participants Est. completion 2025-01-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06920056
A Study of BGM0504 in Overweight or Obese Participants
Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 28 participants Est. completion 2025-07-25 1 site Stand-aloneOther conditions: Overweight or ObeseView official trial listing → -
Not yet recruiting NCT NCT06942390
Topical Metformin Versus Topical Ketotifen in Melasma Treatment
Not yet reported Assiut University 60 participants Est. completion 2026-10-30 Stand-aloneOther conditions: MelasmaView official trial listing → -
Not yet recruiting NCT NCT06946628
New Triple Therapy in Newly Diagnosed Type 2 Diabetes
Not yet reported Sun Yat-sen University 296 participants Est. completion 2030-12-31 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Enrolling by invitation NCT NCT06959784
Assessing Incretin Therapy for Cardiovascular Risk Reduction and Diabetes Remission( ITCRDR Study)
Not yet reported China-Japan Friendship Hospital 142 participants Est. completion 2026-12-31 1 siteCardiovascular disease Other conditions: Diabetes Mellitus, Cerebrovascular DiseaseView official trial listing → -
Completed NCT NCT06961019
Clinical Study to Assess the Safety, Efficacy and In-Use Tolerability of Herbal-Based Sugar Support Effervescent Tablets in Type-2 Diabetes Mellitus Patients
Not yet reported NovoBliss Research Pvt Ltd 14 participants Est. completion 2026-03-14 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06965868
Role of the Blood-Brain Barrier in Stress Resilience: Investigating New Pathways Towards Pharmacological Augmentation of Stress Resilience
Not yet reported Leibniz-Institut für Resilienzforschung (LIR) gGmbH 122 participants Est. completion 2027-02 3 sitesOther conditions: Stress Resilience, Blood-Brain Barrier Integrity, Mental HealthView official trial listing → -
Not yet recruiting NCT NCT06975839
Local Metformin Gel and Impacted Lower Third Molar
Not yet reported Fayoum University 36 participants Est. completion 2026-02-01 Stand-aloneOther conditions: Impacted Third Molar ToothView official trial listing → -
Completed NCT NCT06983223
Oral Sucrosomial® Vitamin B12 in the Management of B12 Deficiency Among Metformin-Treated Type 2 Diabetes Patients
Not yet reported Liaquat University of Medical & Health Sciences 50 participants Est. completion 2025-12-03 1 siteType 2 diabetes Other conditions: Vitamin B 12 DeficiencyView official trial listing → -
Completed NCT NCT06995339
Comparative Clinical and Biochemical Study Evaluating the Effectiveness of Metformin Versus Febuxostat on Gouty Obese Non-Diabetic Patients
Not yet reported Mostafa Bahaa 60 participants Est. completion 2025-12-30 1 siteOther conditions: GoutView official trial listing → -
Not yet recruiting NCT NCT06999343
Exploring the Anti-ageing Effects of Metformin in COPD
Not yet reported Fundación Instituto de Investigación Sanitaria de Navarra 212 participants Est. completion 2029-09-01 Stand-aloneOther conditions: COPDView official trial listing → -
Active, not recruiting NCT NCT07003191
Metformin Hydrochloride and Empagliflozin Tablets in the Treatment of Type 2 Diabetes
Sun Yat-sen University 2600 participants Est. completion 2025-12-31 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT07007221
Clinical Trials to Evaluate Metformin to Treat Depression in People Living With HIV
Not yet reported University of Minnesota Est. completion 2030-12-01 Stand-aloneOther conditions: Depression, HivView official trial listing → -
Active, not recruiting NCT NCT07026968
A Study of Prusogliptin Tablets Combined With Dapagliflozin Tablets and Metformin Hydrochloride Extended Release Tablets in Type 2 Diabetes
Not yet reported CSPC Ouyi Pharmaceutical Co., Ltd. 815 participants Est. completion 2026-11-13 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07027969
Metabolic Surgery for Atrial Fibrillation Elimination
Not yet reported Ali Aminian 100 participants Est. completion 2030-03-31 1 siteOther conditions: Atrial Fibrillation, Obesity and Obesity-related Medical ConditionsView official trial listing → -
Active, not recruiting NCT NCT07033585
Generic Drugs (Dapagliflozin and Saxagliptin) Treat Type 2 Diabetes Patients With Controlled Cancers
Not yet reported, Not yet reported Han Xu, M.D., Ph.D., FAPCR, Medical Director,, IRB Chair 600 participants Est. completion 2026-11-28 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07055958
Effect of Metformin as Add-on Therapy in Levodopa Treated Parkinson's Disease Patients
Not yet reported Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 74 participants Est. completion 2025-07-20 1 site Stand-aloneOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT07057271
A Study of CJC-1134-PC Injection in Patients With Type 2 Diabetes With Inadequately Controlled Blood Glucose Level After Metformin Monotherapy or Metformin in Combination With Insulin Secretagogues
Not yet reported Changshan ConjuChem BioPharmaceutical Research and Development (Hebei) Co., Ltd. 464 participants Est. completion 2023-02-21 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT07057479
Phase III Trial of SGLT2 Inhibitor and Thiazolidinedione Fixed-Dose Combination vs. Monotherapy in Type 2 Diabetes Patients on Metformin
Not yet reported Eurofarma Laboratorios S.A. Est. completion 2028-02 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07058675
Myoinositol vs. Metformin for Polycystic Ovarian Syndrome (PCOS): Impact on Metabolic Health and Fertility
Not yet reported Benha University 156 participants Est. completion 2025-06-18 1 siteOther conditions: PCOSView official trial listing → -
Completed NCT NCT07061496
Comparative Effects of Exercise and Metformin on Glycemic Control in Prediabetic Adults
Not yet reported Asad Ullah Jan 226 participants Est. completion 2026-03-15 1 siteOther conditions: Pre Diabetic, Pre DiabetesView official trial listing → -
Completed NCT NCT07066722
A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults
Not yet reported ViiV Healthcare 126 participants Est. completion 2025-12-17 2 sites Stand-aloneOther conditions: HIV InfectionsView official trial listing → -
Completed NCT NCT07072949
The Impact of Ursodeoxycholic Acid and Probiotics on Metabolic Outcomes in Type 2 Diabetic Patients Taking Metformin
Not yet reported University of Banja Luka 90 participants Est. completion 2024-01-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07073157
Effect of HRS-8427 for Injection on the Pharmacokinetics of Furosemide and Metformin in Healthy Subjects。
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 24 participants Est. completion 2025-08-15 1 site Stand-aloneOther conditions: Health VolunteerView official trial listing → -
Enrolling by invitation NCT NCT07073768
Comparison Between Efficacy of Trelagliptin and Sitagliptin in Type II Diabetic Patients
Not yet reported Khyber Medical College, Peshawar 126 participants Est. completion 2026-12-30 1 site Stand-aloneType 2 diabetes Other conditions: Glycemic Control for Diabetes MellitusView official trial listing → -
Completed NCT NCT07076056
Clinical Trial to Evaluate the Efficacy and Safety of DW1026C1 or DW1026C2
Not yet reported Daewon Pharmaceutical Co., Ltd. 230 participants Est. completion 2024-06-19 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07077525
Effect of Vildagliptin Versus Dapagliflozin as Add on Therapy to Metformin on Cardiovascular Risk Factors
Not yet reported Al-Azhar University 196 participants Est. completion 2024-08-31 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07086859
Alveolar Ridge Preservation Using Autogenous Whole Tooth Graft With 1 %Metformin :A Randomized Controlled Clinical Trial
Not yet reported Cairo University 24 participants Est. completion 2026-03-30 1 site Stand-aloneOther conditions: Dimensional Changes After Tooth Extraction, Tooth Extraaction, Socket PreservationView official trial listing → -
Not yet recruiting NCT NCT07088523
Traditional Chinese Medicine Intervention for Ischemic Cardiovascular Disease Comorbid With Diabetes Mellitus: An Efficacy Comparative Study
Not yet reported Guangzhou University of Traditional Chinese Medicine 4205 participants Est. completion 2027-12-31 1 siteCardiovascular disease Other conditions: Diabete MellitusView official trial listing → -
Not yet recruiting NCT NCT07113756
New Topical Treatment in Plaque Psoriasis
Not yet reported Sohag University 70 participants Est. completion 2026-09-01Other conditions: Plaque PsoriasisView official trial listing → -
Completed NCT NCT07120828
The Role of CYP8B1 Polymorphisms in Modulating the Biochemical Pathways Affected by SGLT2 Inhibitors in T2DM and Obesity
Not yet reported Erbil Polytechnic University 260 participants Est. completion 2026-03-15 1 siteType 2 diabetes Other conditions: Obese Diabetics, Obese Patients (BMI ≥ 30 kg/m²)View official trial listing → -
Not yet recruiting NCT NCT07121088
Traditional Chinese Medicine Intervention for Ischemic Cerebrovascular Disease and Diabetes Mellitus: An Efficacy Comparative Study
Not yet reported Guangzhou University of Traditional Chinese Medicine 3666 participants Est. completion 2027-12-31Other conditions: Ischemic Cerebral Infarction, Diabetes MellitusView official trial listing → -
Completed NCT NCT07121959
A Study of Belzutifan (MK-6482) and Metformin in Healthy Adult Participants (MK-6482-039)
Not yet reported Merck Sharp & Dohme LLC 14 participants Est. completion 2025-09-26 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Not yet recruiting NCT NCT07136987
A Trial of 2 Disease-Modifying Drugs (Metformin and N-acetylcysteine ) to Promote TB Lung Function Recovery
Not yet reported Open Source Pharma Foundation 1104 participants Est. completion 2031-07 Stand-aloneOther conditions: TuberculosisView official trial listing → -
Not yet recruiting NCT NCT07139405
TriGlytza®-01 Versus Metformin in Overweight and Obese Adults With Type 2 Diabetes and Inadequate Glycaemic Control Despite Metformin Therapy
Not yet reported Myopharm Limited 48 participants Est. completion 2027-12-30 3 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07145827
Effect of Metformin on Endometrial Thickness in Postmenopausal Breast Cancer Patients Receiving Tamoxifen
Not yet reported Uruk University 60 participants Est. completion 2025-07-01 1 site Stand-aloneOther conditions: Breast Cancer, Endometrial Hyperplasia and Endometrial CancersView official trial listing → -
Not yet recruiting NCT NCT07156539
A Phase 3 Study of HS-20094 in Patients With T2DM
Not yet reported Jiangsu Hansoh Pharmaceutical Co., Ltd. 546 participants Est. completion 2027-05-30 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT07158411
Evaluate the Effect of Vimseltinib on Organic Cation Transporter 2 (OCT2)
Not yet reported Deciphera Pharmaceuticals, LLC 22 participants Est. completion 2026-01-30 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Not yet recruiting NCT NCT07165158
The Effect of Semaglutide on Bone Health
Not yet reported The First Affiliated Hospital of Xiamen University 150 participants Est. completion 2026-12-31 1 site Stand-aloneType 2 diabetes Other conditions: Osteoporosis, Osteoporosis FractureView official trial listing → -
Completed NCT NCT07172269
Mangosteen Supplement as Adjuvant Therapy With Sitagliptin/Metformin in Iraqi Patients With Type 2 Diabetes
Not yet reported Mais Qais Hbeeb 58 participants Est. completion 2025-05-26 1 site Stand-aloneType 2 diabetes Other conditions: Diabete Mellitus, Dyslipidemia in Patients With Diabetes Mellitus, Insulin ResistanceView official trial listing → -
Not yet recruiting NCT NCT07173712
Regimen Transition After Short-Term Intensive Insulin Therapy in Type 2 Diabetes
Not yet reported Yanbing Li 324 participants Est. completion 2027-12-31Type 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07176338
Role of Metformin in Posterior Capsule Opacification
Not yet reported Vienna Institute for Research in Ocular Surgery 40 participants Est. completion 2025-10-01 1 site Stand-aloneType 2 diabetes Other conditions: CataractView official trial listing → -
Enrolling by invitation NCT NCT07179042
Intertrochanteric Femur Fracture Patients Who Receive Metformin With a Placebo
Not yet reported University of Utah 60 participants Est. completion 2030-09 1 site Stand-aloneOther conditions: Intertrochanteric Femur Fracture, Muscle AtrophyView official trial listing → -
Enrolling by invitation NCT NCT07209527
Truway Diagnostic Tools in Primary Care
Not yet reported Truway Health, Inc. 200 participants Est. completion 2028-10-01 1 site Stand-aloneType 2 diabetesCardiovascular diseaseChronic kidney diseaseMetabolic syndromePrediabetes Other conditions: Chronic Disease, Hypertension, Hyperlipidemia, Peripheral Artery DiseaseView official trial listing → -
Completed NCT NCT07213895
Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCL 25mg/5mg/1000mg Extended-Release Tablets Versus Trijardy® XR Extended Release Film Coated Tablets
Not yet reported Humanis Saglık Anonim Sirketi 14 participants Est. completion 2025-09-18 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07215156
Metformin Versus Chlorhexidine Gel as Adjuncts to Scaling and Root Planing in Stage II Grade B Periodontitis
Not yet reported Kafrelsheikh University 60 participants Est. completion 2026-06-01 Stand-aloneOther conditions: Stage II, Grade B Periodontitis, Chronic PeriodontitisView official trial listing → -
Completed NCT NCT07216131
A Study to Investigate the Effect of AZD0780 on Metformin Pharmacokinetics in Healthy Adult Volunteers Aged 18 to 55 Years
Not yet reported AstraZeneca 14 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT07222098
A Clinical Study of Calderasib (MK-1084) With Rosuvastatin and Metformin in Healthy People (MK-1084-016)
Not yet reported Merck Sharp & Dohme LLC 16 participants Est. completion 2025-12-29 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT07223671
Study to Evaluate the Effect of Repotrectinib on the Drug Levels of Transporter and CYP P450 Probe Substrates in Healthy Adult Participants
Not yet reported Bristol-Myers Squibb 30 participants Est. completion 2026-03-19 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Not yet recruiting NCT NCT07229534
Clinical Trial to Evaluate the Efficacy and Safety of DA-5218 in Patients With Type 2 Diabetes
Not yet reported Dong-A ST Co., Ltd. 238 participants Est. completion 2027-11Other conditions: Diabete MellitusView official trial listing → -
Not yet recruiting NCT NCT07241897
DPP4 Inhibitor Intervention on Post-stroke Cognitive Impairment in Ischemic Stroke Patients With Type 2 Diabetes
Not yet reported Second Affiliated Hospital of Soochow University 312 participants Est. completion 2028-04-30 1 site Stand-aloneCardiovascular disease Other conditions: Diabete MellitusView official trial listing → -
Active, not recruiting NCT NCT07244770
The Effects of Some Antihyperglycemic Drugs on Cognitive Function and Risk of Depression of Diabetic Patients
Beni-Suef University 300 participants Est. completion 2026-12-30 1 siteOther conditions: MCIView official trial listing → -
Completed NCT NCT07247656
The Efficacy and Safety of Empagliflozin - Linagliptin and Empagliflozin- Metformin Therapy in Reduction of Body Weight in Type 2 Diabetic Patients .
Not yet reported Bahria University 200 participants Est. completion 2023-05-01 1 siteOther conditions: Diabete MellitusView official trial listing → -
Completed NCT NCT07266766
Bioequivalence Study to Compare Empagliflozin / Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg
Not yet reported Humanis Saglık Anonim Sirketi 40 participants Est. completion 2025-10-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07266779
Bioequivalence Study of Test Product (T) of Ertugliflozin/Metformin 7.5 mg/ 1000 mg Film Coated Tablets and Reference Product (R) of Segluromet 7.5 mg/ 1000 mg Film Coated Tablets in Healthy, Adult, Human Subjects Under Fed Condition.
Not yet reported Humanis Saglık Anonim Sirketi 36 participants Est. completion 2025-10-11 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07272109
Active Anti-diabetic Treatment Plus Chemotherapy for Pancreatic Cancer Related Diabetes
Not yet reported Fudan University 210 participants Est. completion 2028-12-30 1 site Stand-aloneOther conditions: Pancreatic CancerView official trial listing → -
Not yet recruiting NCT NCT07272967
Metformin in Preventing Secondary Gliosis Following Acute Thoraco-Lumbar Spinal Cord Injury
Not yet reported Badr University 34 participants Est. completion 2026-02-01 1 siteOther conditions: Spinal Cord Injury (SCI)View official trial listing → -
Active, not recruiting NCT NCT07274644
Effects of iGlarLixi Versus iGlar on Liver Fat Content in Patients With Type 2 Diabetes Mellitus Combined With Metabolic Dysfunction-associated Steatotic Liver Disease
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 36 participants Est. completion 2026-07-30 1 site Stand-aloneMASLDType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07275359
Investigating Senolytic Properties in Pulmonary Rehabilitation and Metformin in COPD Exacerbations
Not yet reported Duke University 45 participants Est. completion 2029-10-02 1 site Stand-aloneOther conditions: Chronic Obstructive Pulmonary Disease (COPD)View official trial listing → -
Active, not recruiting NCT NCT07279909
Phase-III Clinical Studies on Poly Herbal Anti-Diabetic Formulation
Not yet reported Hamdard University 500 participants Est. completion 2026-05-20 1 siteOther conditions: Diabetes Type 2, Diabetes Mellitus, Experimental, HbA1c, Urinary Glucose, Ability of Experimental Drug to Lower HbA1c Compare to MetforminView official trial listing → -
Enrolling by invitation NCT NCT07280572
RECLAIM Adaptive Platform Trial for PCC Treatments
Not yet reported Janneke van de Wijgert 1250 participants Est. completion 2027-12-01 1 site Stand-aloneOther conditions: Post COVID ConditionView official trial listing → -
Not yet recruiting NCT NCT07289750
The Effect of Alogliptin Combined With Actoplus Met on Glucose and Lipid Metabolism and Pancreatic Function in Patients With T2DM Complicated With MAFLD
Not yet reported The Fourth Affiliated Hospital of Zhejiang University School of Medicine 80 participants Est. completion 2027-08-31Type 2 diabetes Other conditions: MAFLDView official trial listing → -
Not yet recruiting NCT NCT07300007
PK and Relative Bioavailability of Liquid Metformin vs Tablets in Healthy Adults
Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-05-28 Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Not yet recruiting NCT NCT07300020
PK and Relative Bioavailability of Novel Liquid Metformin vs Tablets
Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-06-28 Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Not yet recruiting NCT NCT07300033
Bioequivalence Study of Liquid Metformin (100 and 250 mg/mL) vs IR Tablets
Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-07-28 Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Not yet recruiting NCT NCT07300046
Tolerability Study of Liquid Metformin (100 and 250 mg/mL) vs IR Tablets
Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-08-28 Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Not yet recruiting NCT NCT07300059
Short-Term Glycemic Effects of Liquid Metformin vs Standard Tablets
Not yet reported Aspargo Labs, Inc 24 participants Est. completion 2026-08-28 Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT07302932
Metformin and Molecular Aging in Prediabetes
Not yet reported Diabetes Foundation, India 112 participants Est. completion 2025-01-30 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT07303127
Combination of Bitter Melon Extract and Snakehead Fish Powder to Reduce Glycaemia in Type 2 Diabetes Mellitus
Not yet reported Universitas Muhammadiyah Surakarta 80 participants Est. completion 2021-10-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07303556
Improving Cardiovascular Disease Diagnosis and Treatment in Kazakhstan Using Metabolic Correction With GLP-1 Drugs
Not yet reported Nazarbayev University 120 participants Est. completion 2026-11-01 1 site Added to GLP-1Heart failure Other conditions: Diabete Type 2, Arterial HypertensionView official trial listing → -
Not yet recruiting NCT NCT07311551
A Comparison of Effectiveness, Safety, and Cost-effectiveness of Dapagliflozin and Empagliflozin in Patients With Type 2 Diabetes Mellitus and High Body Mass Index (BMI)
Not yet reported Bhavya Bhavya, MD 112 participants Est. completion 2026-12 Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07321223
Comparison of Different Doses of Vitamin D Supplementation on Glycated Haemoglobin and Blood Glucose Parameters With Type II Diabetes Mellitus Having Vitamin d Deficiency
Not yet reported University of Lahore 108 participants Est. completion 2026-02-22 1 siteOther conditions: Diabetes (DM), Vitamin D DeficiencyView official trial listing → -
Not yet recruiting NCT NCT07323381
Effects of Henagliflozin Proline and Metformin XR on Body Composition in Geriatric Patients With Newly Diagnosed T2DM
Not yet reported Bin Lu 116 participants Est. completion 2027-09-30Other conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT07323589
Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS
Not yet reported PAEC general hospital 120 participants Est. completion 2025-10-25 1 site Stand-aloneOther conditions: PCOS (Polycystic Ovary Syndrome)View official trial listing → -
Completed NCT NCT07333742
A Clinical Study to See How the Body Handles and How Safe a Combination Tablet of Gemigliptin, Dapagliflozin, and Metformin 50/10/1000mg is Compared to Taking Gemigliptin 50mg Separately With Dapagliflozin/Metformin 10/1000mg in Healthy Adults After a Meal
Not yet reported LG Chem 50 participants Est. completion 2025-11-27 1 site Stand-aloneOther conditions: Fed Conditions, Healthy VolunteerView official trial listing → -
Completed NCT NCT07336914
Effect of Conventional vs Intensive Management on Gestational Diabetes and Maternal Fetal Outcomes
Not yet reported Khyber Medical University Peshawar 60 participants Est. completion 2026-04-25 2 sites Stand-aloneOther conditions: Gestational DiabetesView official trial listing → -
Not yet recruiting NCT NCT07342764
Dapagliflozin Versus Metformin for the Management of Antipsychotic-Induced Weight Gain: A Pragmatic Pilot Randomized Controlled Trial
Not yet reported Sultan Qaboos University 110 participants Est. completion 2028-12 1 siteOther conditions: Antipsychotic-induced Weight Gain (AIWG), Antipsychotic-induced Weight GainView official trial listing → -
Completed NCT NCT07345507
Comparison of Efficacy of Metformin Gel 30% vs Triple Combination Cream (Hydroquinone 4%, Flucinolone Acetonide 0.01%, Tretinoin 0.025%) in Treatment of Melasma in Tertiary Care Hospital Karachi
Not yet reported Jinnah Postgraduate Medical Centre 34 participants Est. completion 2025-08-30 1 site Stand-aloneOther conditions: MelasmaView official trial listing → -
Completed NCT NCT07357337
Efficacy of Oral Metformin vs Oral Doxycycline in Treating Acne Vulgaris
Not yet reported Ghurki Trust and Teaching Hospital 68 participants Est. completion 2025-10-01 1 site Stand-aloneOther conditions: Acne Vulgaris on the Face, Acne VulgarisView official trial listing → -
Active, not recruiting NCT NCT07362030
Drug-durg Interaction of RAY1225 With Warfarin, Atorvastatin, Metformin and Digoxin
Not yet reported Guangdong Raynovent Biotech Co., Ltd 32 participants Est. completion 2026-03-30 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT07363707
A Study Between Dapagliflozin and Empagliflozin Effect on NAFLD in Patients With Type 2 Diabetes.
Not yet reported Beni-Suef University 108 participants Est. completion 2024-03-01 1 siteMASLDView official trial listing → -
Not yet recruiting NCT NCT07365358
Evaluate the Efficacy and Safety of Empagliflozin or Glimepiride Combination Therapy in Type 2 Diabetes Mellitus Patients
Not yet reported Chong Kun Dang Pharmaceutical 200 participants Est. completion 2027-08 1 siteOther conditions: Diabete Type 2View official trial listing → -
Completed NCT NCT07368569
A Study in Healthy People to Test Whether BI 764198 Influences the Amount of Metformin in the Body
Not yet reported Boehringer Ingelheim 14 participants Est. completion 2026-03-17 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT07372118
Bioequivalence Study to Compare Empagliflozin / Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg in Fast Condition
Not yet reported Humanis Saglık Anonim Sirketi 32 participants Est. completion 2026-01-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07375654
Combined Use of Cyclosporine and Metformin in Treatment of Psoriasis vs Cyclosporine Alone
Not yet reported Cairo University 32 participants Est. completion 2025-11-04 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT07380841
Metformin vs Inositol vs Diet vs Combination Therapy in PCOS
Not yet reported Islamabad Medical and Dental College 192 participants Est. completion 2026-01-13 1 site Stand-aloneMetabolic syndrome Other conditions: Polycystic Ovary Syndrome, Insulin ResistanceView official trial listing → -
Completed NCT NCT07387679
Myo-inositol Versus Metformin in Patients With Polycystic Ovarian Syndrome to Treat Obesity
Not yet reported Muhammad Aamir Latif 60 participants Est. completion 2025-05-28 1 site Stand-aloneOther conditions: Polycystic Ovarian SyndromeView official trial listing → -
Not yet recruiting NCT NCT07395895
Effect of Metformin Iontophoresis on Knee Osteoarthritis in Postmenopausal Women
Not yet reported Badr University 68 participants Est. completion 2026-05-01 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT07396844
The Food Effect on Pharmacokinetics of Fixed Dose Combination of Gemigliptin/Dapagliflozin/Metformin in Healthy Volunteers
Not yet reported LG Chem 28 participants Est. completion 2026-06-26 1 site Stand-aloneOther conditions: Healthy, Fasting, FedView official trial listing → -
Completed NCT NCT07399470
A Clinical Study in Healthy Adults to See How the Body Processes and How Safe a Tablet That Combines Gemigliptin, Dapagliflozin, and Metformin is, Compared With Taking Zemiglo and Xigduo XR Together While Fasting.
Not yet reported LG Chem 58 participants Est. completion 2026-02-06 1 site Stand-aloneOther conditions: Healthy Volunteers, Fasting ConditionsView official trial listing → -
Completed NCT NCT07399535
Clinical Investigation of Herbal Formulation and Its Efficacy in Polycystic Ovarian Syndrome
Not yet reported Jinnah Postgraduate Medical Centre 116 participants Est. completion 2026-03-01 1 site Stand-aloneOther conditions: Polycystic Ovarian Syndrome (PCOS), Herbal Medicine, Infertility, Metabolic DisorderView official trial listing → -
Completed NCT NCT07412015
Pilot Bioequivalence Study of Chiglitazar/Metformin Extended-Release Tablets
Not yet reported Chipscreen Biosciences, Ltd. 24 participants Est. completion 2026-05-28 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07415226
Glucose-lowering Drugs as an Adjunct to Insulin Therapy in Chinese Patients With Type 1 Diabetes
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 500 participants Est. completion 2027-12-31Other conditions: Type 1 Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT07417306
A Study of HDM1005 in Participants With T2DM Not Controlled With Metformin Alone or in Combination With a Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 912 participants Est. completion 2027-12-31 1 siteType 2 diabetesView official trial listing → -
Suspended NCT NCT07433062
A Study to Evaluate the Effect of AZD6793 on the Pharmacokinetics and Pharmacodynamics of Metformin in Participants With Type 2 Diabetes Mellitus
Not yet reported AstraZeneca 28 participants Est. completion 2026-06-18 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07436182
Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. Metformin Monotherapy
Not yet reported Mansoura University 176 participants Est. completion 2026-06-01 1 site Stand-aloneOther conditions: Mitochondria, MetforminView official trial listing → -
Completed NCT NCT07437612
Cryotherapy and Intracanal Medicaments for Postoperative Pain in Apical Periodontitis
Not yet reported Celalettin Topbaş 80 participants Est. completion 2024-01-01 1 siteOther conditions: Symptomatic Apical Periodontitis, Pulp NecrosisView official trial listing → -
Not yet recruiting NCT NCT07441187
Efficacy and Safety of Henagliflozin, Retagliptin, and Metformin Extended-Release Tablets in Chinese Patients With Type 2 Diabetes Mellitus
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 300 participants Est. completion 2027-12-31Type 2 diabetesView official trial listing → -
Completed NCT NCT07451639
White Mulberry Leaf Extract for Metabolic Health in Overweight Adults Taking Metformin
Not yet reported Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo 50 participants Est. completion 2024-06-01 1 siteOther conditions: Weight ManagementView official trial listing → -
Completed NCT NCT07451938
A Cohort Study on Obese Patients' Multidisciplinary Integrated Health Management
China-Japan Friendship Hospital 1500 participants Est. completion 2025-07-30 1 siteOther conditions: Obesity, Diabete Type 2, Bariatric SurgeryView official trial listing → -
Enrolling by invitation NCT NCT07452913
Metformin, Empagliflozin With Sitagliptin vs Linagliptin in Type 2 Diabetes
Not yet reported Bahria University 110 participants Est. completion 2026-06-30 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07459595
Metformin Versus Myo-inositol in the Management of Polycystic Ovarian Disease: A Comparative Study
Not yet reported Fatima Tariq 60 participants Est. completion 2026-07-31 1 siteOther conditions: Polycystic Ovarian Syndrome (PCOS)View official trial listing → -
Not yet recruiting NCT NCT07460336
Effects of Cofrogliptin on Beta-Cell Function in LADA Patients
Not yet reported Second Xiangya Hospital of Central South University 84 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Latent Autoimmune Diabetes in Adults (LADA)View official trial listing → -
Completed NCT NCT07462078
The Effect of Lifestyle Modification on the Risk of Prediabetes Among Patients Attending Outpatient Clinic.
Not yet reported Kasr El Aini Hospital 124 participants Est. completion 2025-06-02 1 site Stand-alonePrediabetesView official trial listing → -
Completed NCT NCT07469254
Adding 1% Metformin Gel to Bone Graft in Association With Immediate Dental Implants
Not yet reported Al-Azhar University 20 participants Est. completion 2025-09-01 1 site Stand-aloneOther conditions: Metformin Gel, Bone Graft, Immediate Dental ImplantsView official trial listing → -
Completed NCT NCT07472179
Effect of Pioglitazone vs Metformin on Clinical, Biochemical and Hormonal Parameters of Insulin Resistant PCOS
Not yet reported Mst.Sumyara Khatun 60 participants Est. completion 2026-02-20 1 site Stand-aloneOther conditions: PCOS(Insulin Resistant)View official trial listing → -
Active, not recruiting NCT NCT07475546
Combination Gerotherapeutic Interventions for Healthspan Improvement
Not yet reported AgelessRx 30 participants Est. completion 2026-04 1 site Stand-aloneOther conditions: Healthspan Improvement, Aging, LongevityView official trial listing → -
Not yet recruiting NCT NCT07485777
Comparative Evaluation of Topical 30% Metformin and Kligman's Regimen in Women With Melasma
Not yet reported Foundation University Islamabad 82 participants Est. completion 2027-06-01 1 site Stand-aloneOther conditions: Melasma (Facial Melasma), MelasmaView official trial listing → -
Not yet recruiting NCT NCT07487103
Efficacy and Safety of QLG1091 vs Rybelsus as add-on to Metformin in Subjects With Type 2 Diabetes
Not yet reported Qilu Pharmaceutical Co., Ltd. 478 participants Est. completion 2027-05Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07495748
Comparative Evaluation of Topical Metformin and Topical Tranexamic Acid in Melasma
Not yet reported Foundation University Islamabad 70 participants Est. completion 2027-07-01 1 site Stand-aloneOther conditions: MelasmaView official trial listing → -
Not yet recruiting NCT NCT07502001
Influence of HDM1005 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 42 participants Est. completion 2027-06-02 1 site Stand-aloneOther conditions: Overweight, ObesityView official trial listing → -
Not yet recruiting NCT NCT07511010
Food Effect and Multiple-Dose Study of Chiglitazar/Metformin Extended-Release Tablets
Not yet reported Chipscreen Biosciences, Ltd. 28 participants Est. completion 2026-10-26 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07513480
Pretreatment With CPA-EE, Metformin and Myoinositol in PCOS With High AMH
Not yet reported Mst.Sumyara Khatun 68 participants Est. completion 2026-02-20 1 site Stand-aloneOther conditions: PCOSView official trial listing → -
Not yet recruiting NCT NCT07516821
Efficacy of Topical Metformin in Psoriasis Vulgaris
Not yet reported Cairo University 55 participants Est. completion 2026-09-01 1 siteOther conditions: Psoriasis VulgarisView official trial listing → -
Completed NCT NCT07519265
Bioequivalence Study of Chiglitazar/Metformin Extended-Release Tablets
Not yet reported Chipscreen Biosciences, Ltd. 64 participants Est. completion 2026-08-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07520110
Metformin to Attenuate Progressive Respiratory Decline in Idiopathic Pulmonary Fibrosis
Not yet reported University of Massachusetts, Worcester 800 participants Est. completion 2029-03-15 15 sites Stand-aloneOther conditions: Idiopathic Pulmonary FibrosisView official trial listing → -
Completed NCT NCT07530289
A Clinical Study of Ulonivirine (MK-8507) With Atorvastatin and Metformin in Healthy Adults (MK-8507-018)
Not yet reported Merck Sharp & Dohme LLC 12 participants Est. completion 2026-06-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT07531108
Effects of Empagliflozin-Metformin, Sitagliptin-Metformin, and Metformin on Adipokines in Type 2 Diabetes
Not yet reported Hawler Medical University 186 participants Est. completion 2025-11-27 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07536620
Metformin and Alveolar Cleft
Not yet reported Fayoum University 36 participants Est. completion 2027-05-30 Stand-aloneOther conditions: Alveolar CleftView official trial listing → -
Completed NCT NCT07541456
Empagliflozin Versus Non-SGLT2 Oral Drugs for Blood Pressure in Type 2 Diabetes
Not yet reported Dr. Zarmina Younes 300 participants Est. completion 2025-11-08 1 siteType 2 diabetes Other conditions: HypertensionView official trial listing → -
Completed NCT NCT07541807
Assessing Changes in Gadoxetate Metabolism by the Liver Using MRI
Sheffield Teaching Hospitals NHS Foundation Trust 12 participants Est. completion 2025-02-28 2 sitesOther conditions: Liver DysfunctionView official trial listing → -
Completed NCT NCT07567781
A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.
Not yet reported AbbVie 12 participants Est. completion 2026-07-21 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Enrolling by invitation NCT NCT07568574
Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes
Not yet reported Enhanced Emirates Limited 60 participants Est. completion 2033-03-01 1 site Stand-aloneOther conditions: Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite AthletesView official trial listing → -
Completed NCT NCT07570082
Drug-Drug Interaction Study of Atumelnant in Healthy Participants
Not yet reported Crinetics Pharmaceuticals Inc. 46 participants Est. completion 2026-07-30 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT07582471
Insulin Versus Oral Hypoglycemic Agents in Gestational Diabetes Mellitus
Not yet reported Dr Mudassar Saeed Pansota 60 participants Est. completion 2026-04-07 1 site Stand-aloneOther conditions: Gestational Diabetes Mellitus (GDM)View official trial listing → -
Completed NCT NCT07585396
Inositol in Letrozol Resistant PCOS Women
Not yet reported, Not yet reported Kafrelsheikh University 136 participants Est. completion 2026-07-11 1 siteOther conditions: Polycystic Ovary Syndrome, InfertilityView official trial listing → -
Completed NCT NCT07586969
Modulation of Hyperandrogenic Anovulation Through Fenugreek Seeds
Not yet reported University of Lahore 70 participants Est. completion 2024-12-11 1 siteOther conditions: Poly Cystic Ovary SyndromeView official trial listing → -
Completed NCT NCT07589075
Sodium-Glucose Co-Transporter-2 Inhibitors as Adjuvant Therapy With Letrozole in Induction of Ovulation
Not yet reported Beni-Suef University 500 participants Est. completion 2025-10-30 1 site Stand-aloneOther conditions: Induction of OvulationView official trial listing → -
Not yet recruiting NCT NCT07589387
Hypertension Treatment in Nigeria: Hypertension Diabetes Integration Study- Formative Aim 3
Not yet reported Washington University School of Medicine 2800 participants Est. completion 2030-01-31 Stand-aloneOther conditions: Diabete MellitusView official trial listing → -
Completed NCT NCT07591402
Metformine as a Protective Factor of Mortality in Type 2 Diabetic Patients Admitted to the ICU for Septic Shock.
Assistance Publique - Hôpitaux de Paris 2740 participants Est. completion 2024-12-15 1 siteOther conditions: D012139, D003924View official trial listing → -
Completed NCT NCT07603505
Effect of NAE on Polycystic Ovarian Syndrome (PCOS)
Not yet reported Jinnah Sindh Medical University 116 participants Est. completion 2026-06-15 1 site Stand-aloneOther conditions: Polycystic Ovarian Syndrome (PCOS), Infertility, Metabolic DisordersView official trial listing → -
Active, not recruiting NCT NCT07604779
Enhancing PCOS Management for Better Outcomes of Intracytoplasmic Sperm Injection
Not yet reported Beni-Suef University 150 participants Est. completion 2027-03-03 1 site Stand-aloneOther conditions: Polycystic Ovarian Syndrome (PCOS)View official trial listing → -
Completed NCT NCT07604870
Krill Oil and Metformin in Women With PCOS and Metabolically Unhealthy Obesity
Not yet reported Firat University 54 participants Est. completion 2024-04-30 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Obesity, MetabolicView official trial listing → -
Not yet recruiting NCT NCT07622290
Metformin Treatment for Children With Obesity-associated Asthma
Not yet reported Prof Ibrahim Janahi 182 participants Est. completion 2028-03 1 siteOther conditions: Obesity-associated AsthmaView official trial listing → -
Completed NCT NCT07627048
Influence of Gut Microbiota on the Development of Type 2 Diabetes Mellitus and Personalization of Diabetes-lowing Therapy
Pirogov Russian National Research Medical University 100 participants Est. completion 2022-04-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07628556
Antidiabetic Medications and Risk of Cancer
University of Pecs 74799 participants Est. completion 2025-12-30 1 siteOther conditions: CancerView official trial listing → -
Not yet recruiting NCT NCT07628985
BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes
Not yet reported Carnot Laboratories 374 participants Est. completion 2027-10 7 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07633015
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 5 mg / 850 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-04-29 1 site Stand-aloneOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Completed NCT NCT07633028
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 850 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-04-08 1 site Stand-aloneOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Completed NCT NCT07633041
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 1000 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-04-04 1 site Stand-aloneOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Completed NCT NCT07633054
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 500 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-11-24 1 site Stand-aloneOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Not yet recruiting NCT NCT07635953
New Triple Combination Therapy in Newly Diagnosed Type 2 Diabetes
Not yet reported Sun Yat-sen University 296 participants Est. completion 2031-07-01 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT07647003
A Study to Evaluate the Effect of Two Fixed-Dose Leucine, Sildenafil and Metformin Combinations on Blood Pressure in Individuals With Hypertension
Not yet reported NuSirt Biopharma 150 participants Est. completion 2027-07-07 Stand-aloneOther conditions: HypertensionView official trial listing → -
Active, not recruiting NCT NCT07659444
Metformin Withdrawal In Metabolic Syndrome
Not yet reported University of Castilla-La Mancha 21 participants Est. completion 2026-09-30 1 site Stand-aloneMetabolic syndrome Other conditions: Glucose IntoleranceView official trial listing → -
Completed NCT NCT07679711
Bioequivalence Study of Sitagliptin/Metformin Extended-Release Tablets in Healthy Subjects
Not yet reported The Affiliated Hospital of Qingdao University 76 participants Est. completion 2023-03-22 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Not yet recruiting NCT NCT07687667
Effects of GLP-1RAs on Fertility Outcomes in Obese Women With PCOS
Not yet reported Peking University Third Hospital 406 participants Est. completion 2029-12 1 siteOther conditions: Polycystic Ovary Syndrome (PCOS), Obesity, Infertility, FemaleView official trial listing → -
Completed NCT NCT07691203
Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCl 25 mg/5 mg/1000 mg Extended Release Tablet Versus Trijardy® XR 25 mg/5 mg/1000 mg Extended- Release Tablets
Not yet reported Humanis Saglık Anonim Sirketi 36 participants Est. completion 2026-07-01 1 site Stand-aloneType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT07694115
Bioequivalence Study to Compare Empagliflozin/ Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg
Not yet reported Humanis Saglık Anonim Sirketi 40 participants Est. completion 2026-07-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07696585
New Topical Treatment in Patchy Alopecia Areata
Not yet reported Sohag University 60 participants Est. completion 2027-12-28Other conditions: Alopecia AreataView official trial listing → -
Enrolling by invitation NCT NCT07696806
Microneedling-Assisted Metformin, Tranexamic Acid, and Modified Kligman's Formula for Melasma
Not yet reported Sameh Sarsik 80 participants Est. completion 2027-08-30 1 site Stand-aloneOther conditions: Melasma (Facial Melasma)View official trial listing → -
Not yet recruiting NCT NCT07699367
Metformin and ACLR Muscle Recovery
Not yet reported University of Utah 40 participants Est. completion 2032-10-01 1 site Stand-aloneOther conditions: Atrophy, Inflammation, Weakness, MuscleView official trial listing → -
Completed NCT NCT07702669
Modified Huanglian Wendan Decoction for Metabolic Syndrome
Not yet reported First Affiliated Hospital of Heilongjiang Chinese Medicine University 180 participants Est. completion 2025-08-31 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Not yet recruiting NCT NCT07708610
Preadmission GLP-1 Receptor Agonist Plus SGLT2 Inhibitor Use and Early Outcomes After Pneumonia Hospitalization in Adults With Type 2 Diabetes
Chung Shan Medical University 71775 participants Est. completion 2026-08-31 1 site Stand-aloneType 2 diabetes Other conditions: PneumoniaView official trial listing → -
Not yet recruiting NCT NCT07728318
Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients
Not yet reported Akhtar Saeed Medical and Dental College 52 participants Est. completion 2027-05-12Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07734558
Evaluation of Neuregulin-4 (NRG4) Levels in Obese and Non-Obese Patients With Type 2 Diabetes Mellitus
GÜLDEN ANATACA 125 participants Est. completion 2026-12-30 1 siteType 2 diabetes Other conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT07738692
Effects of Various Types of Ultrasound Therapy in Knee Osteoarthritis
Not yet reported Horus University 80 participants Est. completion 2026-06-30 1 site Stand-aloneOsteoarthritisView official trial listing → -
Completed NCT NCT07751549
Systemic and Topical Metformin Versus Glycolic Acid Peel for the Treatment of Acanthosis Nigricans
Not yet reported Tanta University 54 participants Est. completion 2026-05-25 1 siteOther conditions: Acanthosis NigricansView official trial listing → -
Not yet recruiting NCT NCT07753252
Phase 1 Study in Healthy Adults to See How Sevabertinib Changes Metformin Levels in the Body
Not yet reported Bayer 40 participants Est. completion 2026-09-28 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Not yet recruiting NCT NCT07753317
Clinical and Radiographic Evaluation of Subgingival 1% Metformin Gel Versus 0.05% Zoledronate Gel as an Adjunct to MINST of Intrabony Defects in Controlled Type 2 DM
Not yet reported Cairo University 30 participants Est. completion 2027-03-01Other conditions: Controlled Type 2 Diabetic Patients With PeriodontitisView official trial listing → -
Completed NCT NCT07759674
Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in Jordan
Not yet reported Jerash Private University 25 participants Est. completion 2023-12-01 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome (PCOS) Women, Insulin Resistance SyndromeView official trial listing → -
Completed NCT NCT07763899
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fast Study.
Not yet reported ADIUM 46 participants Est. completion 2025-11-30 1 site Stand-aloneOther conditions: BioequivalanceView official trial listing → -
Completed NCT NCT07763912
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 50 mg/1000 mg in Healthy Subjects, Fed Study.
Not yet reported ADIUM 46 participants Est. completion 2025-12-05 1 site Stand-aloneOther conditions: BioequivalenceView official trial listing → -
Completed NCT NCT07763951
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fast Study.
Not yet reported ADIUM 46 participants Est. completion 2025-12-14 1 site Stand-aloneOther conditions: BioequivalanceView official trial listing → -
Completed NCT NCT07763964
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Sitagliptin/Metformin in Prolonged-release Tablets With 100 mg/1000 mg in Healthy Subjects, Fed Study.
Not yet reported ADIUM 46 participants Est. completion 2025-12-19 1 site Stand-aloneOther conditions: BioequivalanceView official trial listing → -
Not yet recruiting NCT NCT07768280
Efficacy and Safety of Hebenrun in Patients With Type 2 Diabetes
Not yet reported Jiangxi University of Traditional Chinese Medicine 110 participants Est. completion 2028-03 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07770087
Effect of Metformin Gel on Guided Bone Regeneration Around Immediate Dental Implant at Posterior Maxillary Region
Not yet reported Al-Azhar University 12 participants Est. completion 2025-12-15 2 sites Stand-aloneOther conditions: Metformin Gel, Bone Healing, Guided Bone Regeneration, Crestal Bone Loss, Peri Implant Bone LossView official trial listing → -
Not yet recruiting NCT NCT07770711
Inositol and Metformin Administration in Mediterranean Diet and Low-Carbohydrate Diets in Women With PCOS
Not yet reported Dicle University 90 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: PCOS (Polycystic Ovary Syndrome), Insulin Resistance, Obesity (BMI>30)View official trial listing → -
Not yet recruiting NCT NCT07778719
Metformin-Dapagliflozin Effects on IGF-1 in Male T2DM With MASLD
Not yet reported The 95th Hospital of Putian,Putian, Fujian, China 84 participants Est. completion 2027-12-11 1 site Stand-aloneType 2 diabetesMASLDView official trial listing → -
Not yet recruiting NCT NCT07779811
Topical Metformin Versus Triple Regimen for Epidermal Melasma
Not yet reported Combined Military Hospital, Pakistan 104 participants Est. completion 2027-01-30 1 site Stand-aloneOther conditions: Epidermal Melasma, Facial HyperpigmentationView official trial listing → -
Completed NCT NCT07788378
Metformin in Elderly Patients With Type 2 Diabetes and Muscle Strength, Muscle Mass, and Physical Function: Positive or Negative Correlation?
Fudan University 290 participants Est. completion 2024-12-24 1 siteOther conditions: Diabete Type 2, Muscle Strength, Muscle Mass, Physical Function, MetforminView official trial listing → -
Completed NCT NCT07793838
Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS
Not yet reported Jerash Private University 400 participants Est. completion 2026-08-01 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome (PCOS) WomenView official trial listing → -
Not yet recruiting NCT NCT07796191
Drug-drug Interactions Studies of VC005 Tablets in Healthy Adult Subjects
Not yet reported Jiangsu vcare pharmaceutical technology co., LTD 84 participants Est. completion 2026-11-30 1 site Stand-aloneOther conditions: Healthy Adult ParticipantsView official trial listing → -
Not yet recruiting NCT NCT07796477
A Study of SYH2069 Injection in Participants With T2DM Not Controlled With Diet/Exercise Alone or Metformin
Not yet reported CSPC Ouyi Pharmaceutical Co., Ltd. 240 participants Est. completion 2027-10-19 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07806019
Metformin in Parkinson's Disease: Safety and Efficacy
Not yet reported Jinnah Medical & Dental College 70 participants Est. completion 2027-02-01Other conditions: Parkinsons Disease (PD)View official trial listing → -
Not yet recruiting NCT NCT07810998
Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome
Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2027-05-10Other conditions: Poly Cystic Ovary SyndromeView official trial listing → -
Not yet recruiting NCT NCT07811011
Efficacy of Vildagliptin Versus Metformin in Patients With Polycystic Ovary Syndrome
Not yet reported, Not yet reported Tanta University 70 participants Est. completion 2027-03-30Other conditions: Poly Cystic Ovary SyndromeView official trial listing → -
Completed NCT NCT07811856
Effects of Metformin and Theory-Based Education in Women With Polycystic Ovary Syndrome
Not yet reported Jerash Private University 900 participants Est. completion 2026-08-01 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome (PCOS) WomenView official trial listing → -
Active, not recruiting NCT NCT07821073
Myo-Inositol and Folic Acid for Improving Inflammation in Polycystic Ovary Syndrome
Not yet reported Khyber Medical University Peshawar 50 participants Est. completion 2026-09-30 1 site Stand-aloneOther conditions: Inflammation Biomarkers, Poly Cystic Ovary Syndrome, PCOS (Polycystic Ovary Syndrome)View official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Metformin, glucophage
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
