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Recruiting
NCT NCT06924320
A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes
Not yet reported, Not yet reported
Pfizer
381 participants
Est. completion 2026-09-15
1 site
Stand-alone
Other conditions: Obesity and Obesity-related Medical Conditions
View official trial listing →
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Recruiting
NCT NCT07519135
A Study to Learn About the Medicine Called PF-08653944 in People With and Without Reduced Liver Function
Not yet reported
Pfizer
26 participants
Est. completion 2027-07-09
3 sites
Other conditions: Healthy
View official trial listing →
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Completed
NCT NCT06712836
A Phase 2b Study to Examine the Safety and Efficacy of Once-Weekly MET097 in Adults With Obesity or Overweight
Not yet reported
Pfizer
239 participants
Est. completion 2026-04-30
2 sites
Stand-alone
Other conditions: Obesity, Overweight or Obesity
View official trial listing →
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Completed
NCT NCT06857617
This Study Will Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of MET097 in Adult Participants With Overweight or Obesity
Not yet reported, Not yet reported
Metsera, a wholly owned subsidiary of Pfizer
120 participants
Est. completion 2025-03-15
3 sites
Stand-alone
Other conditions: Obesity and Overweight
View official trial listing →
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Completed
NCT NCT06897202
A Study to Evaluate the Efficacy and Safety of Once-Weekly MET097 in Adults With Obesity or Overweight and T2DM
Not yet reported
Pfizer
133 participants
Est. completion 2026-03-18
29 sites
Stand-alone
Type 2 diabetes
Other conditions: Obesity in Diabetes
View official trial listing →
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Active, not recruiting
NCT NCT06973720
A Phase 2b Study to Evaluate the Efficacy and Safety of Once-Monthly MET097 in Adults With Obesity or Overweight
Not yet reported
Pfizer
268 participants
Est. completion 2026-10-16
5 sites
Stand-alone
Other conditions: Obesity, Overweight or Obesity
View official trial listing →
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Active, not recruiting
NCT NCT07311850
Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity
Not yet reported
Pfizer
3578 participants
Est. completion 2028-04-25
169 sites
Stand-alone
Other conditions: Obesity and Overweight
View official trial listing →
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Active, not recruiting
NCT NCT07400653
A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)
Not yet reported
Pfizer
1078 participants
Est. completion 2028-05-16
188 sites
Type 2 diabetes
Other conditions: Obesity, Overweight and/or Obesity, Overweight, Diabetes, Type 2
View official trial listing →
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Completed
NCT NCT07400679
A Study to Learn How the Study Medicine Called PF-08653944 is Taken up Into the Blood in Adults With Overweight or Obesity
Not yet reported
Pfizer
48 participants
Est. completion 2026-07-08
1 site
Other conditions: Overweight, Obesity, Healthy
View official trial listing →
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Active, not recruiting
NCT NCT07508241
A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or Obesity
Not yet reported
Pfizer
22 participants
Est. completion 2027-01-27
1 site
Other conditions: Obesity, Overweight and/or Obesity, Overweight, Drug Interaction
View official trial listing →
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Not yet recruiting
NCT NCT07794761
A Study to Learn About Safety and Effects of Once-weekly Treatment With Berobenatide in Adults With Obesity Disease in Japan (VESPER-JW)
Not yet reported
Pfizer
180 participants
Est. completion 2029-03-14
12 sites
Other conditions: Obesity
View official trial listing →
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Not yet recruiting
NCT NCT07794774
A Study to Learn About Safety and Effects of Once-monthly Treatment With Berobenatide in Adults With Obesity Disease in Japan (VESPER-JM)
Not yet reported
Pfizer
197 participants
Est. completion 2029-02-21
11 sites
Other conditions: Obesity
View official trial listing →