GLP-1 Market
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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

MET097

Company
Pfizer
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
7 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

7 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Oct 21, 2026

Find a Clinical Trial Near Me

See recruiting studies for MET097 and check eligibility with the study team.

Select conditions
Match
Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT06924320

    A Study of MET233 in Combination With MET097 in Individuals With Obesity or Overweight With or Without Diabetes

    Not yet reported, Not yet reported Pfizer 381 participants Est. completion 2026-09-15 1 site Stand-alone
    Other conditions: Obesity and Obesity-related Medical Conditions
    View official trial listing →
  • Recruiting NCT NCT07519135

    A Study to Learn About the Medicine Called PF-08653944 in People With and Without Reduced Liver Function

    Not yet reported Pfizer 26 participants Est. completion 2027-07-09 3 sites Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Recruiting NCT NCT07595549

    A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

    Not yet reported Pfizer 954 participants Est. completion 2028-06-21 72 sites Stand-alone
    Other conditions: Obesity, Overweight and/or Obesity, Overweight
    View official trial listing →
  • Recruiting NCT NCT07792954

    A Study to Learn About the Study Medicine Called PF-08653944 Taken Once-Weekly Compared to Placebo in Chinese Adults With Overweight or Obesity

    Not yet reported Pfizer 300 participants Est. completion 2028-05-23 34 sites
    Other conditions: Obesity, Overweight
    View official trial listing →
  • Recruiting NCT NCT07794761

    A Study to Learn About Safety and Effects of Once-weekly Treatment With Berobenatide in Adults With Obesity Disease in Japan (VESPER-JW)

    Not yet reported Pfizer 180 participants Est. completion 2029-03-14 34 sites
    Other conditions: Obesity
    View official trial listing →
  • Recruiting NCT NCT07823608

    A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Use a Breathing Machine (PAP) (VESPER-OSA 1)

    Not yet reported Pfizer 258 participants Est. completion 2028-06-18 6 sites
    Other conditions: Apnea, Sleep Disorders, Overweight and/or Obesity
    View official trial listing →
  • Recruiting NCT NCT07845500

    A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity

    Not yet reported Pfizer 660 participants Est. completion 2028-02-16 16 sites
    Other conditions: Obesity, Overweight and/or Obesity, Overweight, Treatment Of Obesity
    View official trial listing →
  • Completed NCT NCT06712836

    A Phase 2b Study to Examine the Safety and Efficacy of Once-Weekly MET097 in Adults With Obesity or Overweight

    Not yet reported Pfizer 239 participants Est. completion 2026-04-30 2 sites Stand-alone
    Other conditions: Obesity, Overweight or Obesity
    View official trial listing →
  • Completed NCT NCT06857617

    This Study Will Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of MET097 in Adult Participants With Overweight or Obesity

    Not yet reported, Not yet reported Metsera, a wholly owned subsidiary of Pfizer 120 participants Est. completion 2025-03-15 3 sites Stand-alone
    Other conditions: Obesity and Overweight
    View official trial listing →
  • Completed NCT NCT06897202

    A Study to Evaluate the Efficacy and Safety of Once-Weekly MET097 in Adults With Obesity or Overweight and T2DM

    Not yet reported Pfizer 133 participants Est. completion 2026-03-18 29 sites Stand-alone
    Type 2 diabetes Other conditions: Obesity in Diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT06973720

    A Phase 2b Study to Evaluate the Efficacy and Safety of Once-Monthly MET097 in Adults With Obesity or Overweight

    Not yet reported Pfizer 268 participants Est. completion 2026-10-16 5 sites Stand-alone
    Other conditions: Obesity, Overweight or Obesity
    View official trial listing →
  • Active, not recruiting NCT NCT07311850

    Efficacy and Safety of MET097 Once-Weekly in People With Overweight or Obesity

    Not yet reported Pfizer 3578 participants Est. completion 2028-04-25 161 sites Stand-alone
    Other conditions: Obesity and Overweight
    View official trial listing →
  • Active, not recruiting NCT NCT07400653

    A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)

    Not yet reported Pfizer 1078 participants Est. completion 2028-05-16 180 sites Stand-alone
    Type 2 diabetes Other conditions: Obesity, Overweight and/or Obesity, Overweight, Diabetes, Type 2
    View official trial listing →
  • Completed NCT NCT07400679

    A Study to Learn How the Study Medicine Called PF-08653944 is Taken up Into the Blood in Adults With Overweight or Obesity

    Not yet reported Pfizer 48 participants Est. completion 2026-07-08 1 site Stand-alone
    Other conditions: Overweight, Obesity, Healthy
    View official trial listing →
  • Active, not recruiting NCT NCT07508241

    A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or Obesity

    Not yet reported Pfizer 22 participants Est. completion 2027-01-27 1 site Stand-alone
    Other conditions: Obesity, Overweight and/or Obesity, Overweight, Drug Interaction
    View official trial listing →
  • Active, not recruiting NCT NCT07575932

    A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity

    Not yet reported Pfizer 940 participants Est. completion 2028-01-05 63 sites Stand-alone
    Other conditions: Overweight, Obesity, Overweight and/or Obesity, Overweight or Obesity, Overnutrition, Nutrition Disorders, Nutritional and Metabolic Diseases, Body Weight
    View official trial listing →
  • Not yet recruiting NCT NCT07794774

    A Study to Learn About Safety and Effects of Once-monthly Treatment With Berobenatide in Adults With Obesity Disease in Japan (VESPER-JM)

    Not yet reported Pfizer 197 participants Est. completion 2029-02-21 28 sites
    Other conditions: Obesity
    View official trial listing →
  • Not yet recruiting NCT NCT07845513

    A Study to Learn About the Study Medicine Called PF-08653944 in Otherwise Healthy Chinese Adults With Overweight or Obesity

    Not yet reported Pfizer 16 participants Est. completion 2027-02-21 1 site Stand-alone
    Other conditions: Overweight, Obesity, Healthy Adults
    View official trial listing →
  • Not yet recruiting NCT NCT07874633

    A Study to Learn About the Study Medicine Called PF-08653944 Taken Once-Monthly Compared to Placebo in Chinese Adults With Overweight or Obesity

    Not yet reported Pfizer 432 participants Est. completion 2028-08-15 2 sites
    Other conditions: Obesity, Overweight
    View official trial listing →
  • Not yet recruiting NCT NCT07876531

    A Study to Learn How Different Forms of the Study Medicine Called Berobenatide is Taken up Into the Blood in Adults With Overweight or Obesity

    Not yet reported Pfizer 144 participants Est. completion 2027-04-06 1 site
    Other conditions: Overweight and/or Obesity, Healthy Participants
    View official trial listing →
  • Not yet recruiting NCT NCT07881757

    A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2)

    Not yet reported Pfizer 258 participants Est. completion 2028-07-20 2 sites
    Other conditions: Apnea, Sleep Disorders, Overweight and/or Obesity
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: MET097, PF-08653944

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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.