About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Memantine Hydrochloride
- Company
- Nantes University Hospital
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 20 recruiting
Efficacy results: Not yet reported
20 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 22, 2026
Find a Clinical Trial Near Me
See recruiting studies for Memantine Hydrochloride and check eligibility with the study team.
Trial details
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Recruiting NCT NCT03550391
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases
Not yet reported Canadian Cancer Trials Group 206 participants Est. completion 2027-12-31 86 sites Stand-aloneOther conditions: Brain MetastasesView official trial listing → -
Recruiting NCT NCT04302870
Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial
Not yet reported, Not yet reported University of Edinburgh 1150 participants Est. completion 2030-12 22 sites Stand-aloneOther conditions: Motor Neuron Disease, Amyotrophic Lateral SclerosisView official trial listing → -
Recruiting NCT NCT04539951
Pragmatic Trial of Obsessive-compulsive Disorder
Not yet reported Shanghai Mental Health Center 1600 participants Est. completion 2028-12-31 1 siteOther conditions: Obsessive-Compulsive DisorderView official trial listing → -
Recruiting NCT NCT04789915
Add-on MEmaNtine to Dopamine Modulation to Improve Negative Symptoms at First Psychosis
Not yet reported Bjorn H. Ebdrup 46 participants Est. completion 2026-12-31 1 siteOther conditions: Psychosis, Negative Symptoms With Primary Psychotic DisorderView official trial listing → -
Recruiting NCT NCT05013892
NTS-WBRT in Brain Metastases
Not yet reported Massachusetts General Hospital 41 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Brain MetastasesView official trial listing → -
Recruiting NCT NCT05045950
Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique
Not yet reported Medical College of Wisconsin 53 participants Est. completion 2029-05 2 sites Stand-aloneOther conditions: Brain MetastasesView official trial listing → -
Recruiting NCT NCT05664464
Glutamate Inhibitors in Glioblastoma
Not yet reported, Not yet reported University of Zurich 120 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: GlioblastomaView official trial listing → -
Recruiting NCT NCT05801380
Monitoring Drug Efficacy in Patients with Alzheimer's Disease
University of the Philippines 60 participants Est. completion 2026-02-14 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Recruiting NCT NCT06007846
A Prospective Study of Memantine in Patients With Cirrhosis and Liver Cancer
Not yet reported, Not yet reported Inova Health Care Services 12 participants Est. completion 2029-07-31 2 sites Stand-aloneOther conditions: Hepatocellular Carcinoma, CirrhosisView official trial listing → -
Recruiting NCT NCT06041789
Effect of Acetylcholinesterase Inhibitors on Bone Metabolism
Not yet reported Duke University 45 participants Est. completion 2027-09 1 siteOther conditions: OsteoporosisView official trial listing → -
Recruiting NCT NCT06275035
Evaluation of Memantine in the Preservation of Memory and Neurocognition Following CSI
Not yet reported Tata Memorial Centre 101 participants Est. completion 2031-01 1 site Stand-aloneOther conditions: Neurocognitive DysfunctionView official trial listing → -
Recruiting NCT NCT06679387
"The Effect of Memantine on the Prevention and Amelioration of Paclitaxel-induced Toxicity in Breast Cancer Patients"
Not yet reported Ain Shams University 80 participants Est. completion 2025-10 1 site Stand-aloneOther conditions: Breast Cancer Early Stage Breast Cancer (Stage 1-3)View official trial listing → -
Recruiting NCT NCT06727773
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
Not yet reported UNC Lineberger Comprehensive Cancer Center 90 participants Est. completion 2029-06-15 1 site Stand-aloneOther conditions: Breast Cancer, Locally Advanced Breast Cancer, Cognitive Impairment, Cognitive Decline, Cognitive Change, Breast Cancer Stage I, Breast Cancer Stage II, Breast Cancer Stage IIIView official trial listing → -
Recruiting NCT NCT06789757
The Study of Atezolizumab, Bevacizumab and Memantine in Patients With Hepatocellular Carcinoma (HCC)
Not yet reported Inova Health Care Services 19 participants Est. completion 2028-01-27 2 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT06862960
Ozanimod in Patients With Alzheimer's Disease
Not yet reported ChenXiaoChun 40 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Recruiting NCT NCT07094438
Study Safety and Efficacy of Deep Brain Stimulation (DBS) and Cervical Deep Lymphoid-venous Anastomosis (LVA) in Alzheimer's Disease
Not yet reported Chinese PLA General Hospital 98 participants Est. completion 2027-07 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Recruiting NCT NCT07139834
Pattern Separation in Major Depressive Disorder
Not yet reported Jeffrey Miller 30 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Major Depressive Disorder (MDD)View official trial listing → -
Recruiting NCT NCT07248228
Memory Avoidance Whole Brain Radiotherapy vs Hippocampal Avoidance Whole Brain Radiotherapy (Athena 2 Trial)
Not yet reported Case Comprehensive Cancer Center 90 participants Est. completion 2028-11 1 site Stand-aloneOther conditions: Brain MetastasesView official trial listing → -
Recruiting NCT NCT07251023
Efficacy and Safety of DMB-I (INN: Latrepirdine) in Patients With Alzheimer Type Dementia
Not yet reported Bigespas LTD 450 participants Est. completion 2027-05 12 sitesOther conditions: Alzheimer Type DementiaView official trial listing → -
Recruiting NCT NCT07560878
Synaptic Mechanisms of Continuous Theta Burst Stimulation in Depression
Not yet reported Mclean Hospital 80 participants Est. completion 2030-12 1 site Stand-aloneOther conditions: Major DepressionView official trial listing → -
Completed NCT NCT00000867
A Study to Evaluate the Use of Memantine In Combination With Anti-HIV Drugs to Treat AIDS Dementia Complex (ADC)
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 120 participants Est. completion 2001-07 19 sitesOther conditions: AIDS Dementia Complex, HIV InfectionsView official trial listing → -
Completed NCT NCT00001344
Dextromethorphan Versus Placebo for Neuropathic Pain
Not yet reported National Institute of Dental and Craniofacial Research (NIDCR) 129 participants Est. completion 2001-02 1 siteOther conditions: Diabetic Neuropathies, Herpes Zoster, NeuralgiaView official trial listing → -
Completed NCT NCT00040261
Clinical Trial of Memantine for Major Depression
Not yet reported National Institute of Mental Health (NIMH) 112 participants Est. completion 2005-03 1 siteOther conditions: DepressionView official trial listing → -
Completed NCT NCT00097916
An Evaluation of the Safety and Efficacy of Memantine in Agitated Patients With Moderate to Severe Alzheimer's Disease
Not yet reported Forest Laboratories 34 participants Est. completion 2006-04 9 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00097942
Evaluation of the Safety and Efficacy of Memantine as Adjunctive Treatment in Schizophrenia Patients
Not yet reported Forest Laboratories 138 participants Est. completion 2005-09 13 sitesOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT00106405
An Evaluation of the Safety and Efficacy of Memantine in Patients With Acute Mania Associated With Bipolar I Disorder
Not yet reported Forest Laboratories 35 participants Est. completion 2005-11 6 sitesOther conditions: Bipolar DisorderView official trial listing → -
Completed NCT NCT00120874
Memantine and Comprehensive, Individualized Management of Alzheimer's Disease and Caregiver Training
Not yet reported NYU Langone Health 20 participants Est. completion 2011-11 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00125515
Memantine and Naltrexone Treatment for Opioid Dependence
Not yet reported New York State Psychiatric Institute 81 participants Est. completion 2008-08 1 siteOther conditions: Opioid DependenceView official trial listing → -
Completed NCT NCT00134901
Effectiveness of Memantine in Treating Cocaine-Dependent Individuals - 2
Not yet reported New York State Psychiatric Institute 81 participants Est. completion 2007-05 1 site Stand-aloneOther conditions: Cocaine-Related DisordersView official trial listing → -
Completed NCT NCT00136747
The Effects of Memantine and Bupropion on Acute, Reinforcing, and Conditioned Effects of Cigarettes - 1
Not yet reported New York State Psychiatric Institute 45 participants Est. completion 2009-05 1 site Stand-aloneOther conditions: Tobacco Use DisorderView official trial listing → -
Completed NCT NCT00136786
Effect of Memantine Versus Bupropion on Smoking Relapse in Nicotine-Dependent Individuals - 3
Not yet reported New York State Psychiatric Institute 25 participants Est. completion 2009-05 1 siteOther conditions: Tobacco Use DisorderView official trial listing → -
Completed NCT NCT00141882
Memantine in Patients With Chronic Glaucoma
Not yet reported Allergan 1119 participants Est. completion 2006-08Other conditions: Open-Angle GlaucomaView official trial listing → -
Terminated NCT NCT00148590
Memantine for the Prevention of Cognitive Dysfunction and Negative Symptoms in Patients With Acute Schizophrenia
Not yet reported M. Schaefer, MD 24 participants Est. completion 2008-12 1 siteOther conditions: SchizophreniaView official trial listing → -
Terminated NCT NCT00148616
Memantine for the Treatment of Cognitive Dysfunction and Negative Symptoms in Patients With Chronic Schizophrenia
Not yet reported M. Schaefer, MD 13 participants Est. completion 2008-12 1 siteOther conditions: Chronic SchizophreniaView official trial listing → -
Completed NCT NCT00168350
Memantine in Patients With Chronic Glaucoma
Not yet reported Allergan 1179 participants Est. completion 2006-09Other conditions: Open-Angle GlaucomaView official trial listing → -
Completed NCT NCT00181298
Memantine in Systemic Lupus Erythematosus
Not yet reported Johns Hopkins University 61 participants Est. completion 2007-05 1 siteOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Completed NCT NCT00183729
Memantine Treatment for Improving Rehabilitation Outcomes and Preventing Depression in Older Adults
Not yet reported Eric Lenze 35 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: DepressionView official trial listing → -
Completed NCT NCT00186498
Memantine to Reduce Neurocognitive Deficits Following Unilateral ECT for the Treatment of a Major Depression
Not yet reported Stanford University 11 participants Est. completion 2008-02 1 site Stand-aloneOther conditions: Depressive Disorder, MajorView official trial listing → -
Completed NCT NCT00187525
A 52 Week Open Label Trial of Memantine for Frontotemporal Lobar Degeneration
Not yet reported University of California, San Francisco Est. completion 2006-10Other conditions: Frontotemporal Lobar DegenerationView official trial listing → -
Status unknown NCT NCT00196703
Memantine and Constraint-Induced Language Therapy in Chronic Poststroke Aphasia:A Randomized Controlled Trial
Not yet reported Gabinete Berthier y Martínez 30 participants Est. completion 2005-09 1 siteCardiovascular disease Other conditions: AphasiaView official trial listing → -
Completed NCT NCT00200538
Efficacy and Tolerability of Memantine in Frontotemporal Dementia (FTD) Patients
Not yet reported Nantes University Hospital 52 participants 1 siteOther conditions: DementiaView official trial listing → -
Completed NCT NCT00234637
Rivastigmine Monotherapy and Combination Therapy With Memantine in Patients With Moderately Severe Alzheimer's Disease Who Failed to Benefit From Previous Cholinesterase Inhibitor Treatment
Not yet reported Novartis 204 participants Est. completion 2005-06 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00235716
A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease
Not yet reported US Department of Veterans Affairs 613 participants Est. completion 2012-10 14 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT00240760
Memantine and Down's Syndrome
Not yet reported King's College London 180 participants 2 sitesOther conditions: Down's Syndrome, Dementia, Learning DisabilitiesView official trial listing → -
Completed NCT NCT00242632
Treatment With Namenda in Women at Risk for Cognitive Decline
Not yet reported Stanford University 22 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: DementiaView official trial listing → -
Completed NCT NCT00246415
A Placebo-Controlled Trial of Memantine for Alcohol Dependence
Not yet reported National Institute on Alcohol Abuse and Alcoholism (NIAAA) 90 participants Est. completion 2005-12 1 siteAlcohol use disorder Other conditions: Alcohol AbuseView official trial listing → -
Completed NCT NCT00255086
The Effect of Memantine on Brain Structure and Chemistry in Alzheimer's Disease Patients
Not yet reported Stanford University 17 participants Est. completion 2010-02 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Active, not recruiting NCT NCT00262470
Treatment of Orthostatic Intolerance
Not yet reported, Not yet reported Satish R. Raj 150 participants Est. completion 2029-12 1 site Stand-aloneOther conditions: Tachycardia, Chronic Orthostatic IntoleranceView official trial listing → -
Completed NCT NCT00264238
Memantine Augmentation in Obsessive-Compulsive Disorder
Not yet reported, Not yet reported Stanford University 15 participants Est. completion 2008-06 1 site Stand-aloneOther conditions: Obsessive-Compulsive DisorderView official trial listing → -
Completed NCT NCT00280774
Memantine for Corticosteroid-Induced Mood and Declarative Memory Changes
Not yet reported University of Texas Southwestern Medical Center 20 participants Est. completion 2007-02 1 siteOther conditions: Physiological Effects of DrugsView official trial listing → -
Terminated NCT NCT00283309
Memantine or Riluzole Prophylaxis for Corticosteroid-induced Mood and Declarative Memory Changes
Not yet reported University of Texas Southwestern Medical Center 20 participants Est. completion 2007-04 1 siteOther conditions: Mood, Memory DeficitView official trial listing → -
Completed NCT NCT00283725
Use of Different Treatment Care Methods in Patients With Dementia Associated With Alzheimer's Disease
Ortho-McNeil Neurologics, Inc. 573 participants Est. completion 2006-12Other conditions: Dementia, Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00294554
Memantine for Treatment of Cognitive Impairment in Patients With Parkinson's Disease and Dementia
Not yet reported Johns Hopkins University 20 participants Est. completion 2008-12 1 siteOther conditions: Parkinson's Disease, Cognitive Impairment, DementiaView official trial listing → -
Completed NCT NCT00300716
Trial of Memantine for Cognitive Impairment in Multiple Sclerosis
Not yet reported, Not yet reported Oregon Health and Science University 82 participants Est. completion 2009-01 4 sitesOther conditions: Multiple Sclerosis, Cognition DisordersView official trial listing → -
Terminated NCT NCT00303433
Namenda to Prevent Post-Operative Delirium
Not yet reported University of Rochester 30 participants Est. completion 2006-09 1 siteOther conditions: Delirium, Post-Operative StatesView official trial listing → -
Completed NCT NCT00305578
Memantine Augmentation of Lamotrigine Incomplete-Response in Bipolar Depression
Not yet reported Indiana University 29 participants Est. completion 2011-12 1 siteOther conditions: Bipolar DepressionView official trial listing → -
Completed NCT NCT00305903
Safety and Tolerability of Rivastigmine With Add-on Memantine in Patients With Probable Alzheimer's Disease
Not yet reported Novartis 150 participants Est. completion 2007-08 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00315666
Prophylactic Effect of Memantine in Chronic Tension-Type Headache
Not yet reported Danish Headache Center 40 participants Est. completion 2007-06 1 siteOther conditions: Tension-Type HeadacheView official trial listing → -
Completed NCT NCT00322153
A Study of the Safety and Efficacy of Memantine in Moderate to Severe Alzheimer's Disease
Not yet reported Forest Laboratories 677 participants Est. completion 2008-01 83 sitesOther conditions: Dementia of the Alzheimer's TypeView official trial listing → -
Completed NCT NCT00330655
An Open-Label Trial of Memantine in the Treatment of Binge Eating Disorder
Not yet reported Mclean Hospital 15 participants Est. completion 2007-07 1 siteOther conditions: Binge Eating DisorderView official trial listing → -
Completed NCT NCT00334906
Study of Memantine in Assessment of Selected Measures of Volumetric Magnetic Resonance Imaging (MRI) and Cognition in Moderate AD (Alzheimer's Disease)
Not yet reported Forest Laboratories 75 participants 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00344682
Memantine Augmentation of Antidepressants
Not yet reported University of Massachusetts, Worcester 31 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Depressive DisorderView official trial listing → -
Completed NCT NCT00353665
Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS)
Not yet reported, Not yet reported University of Lisbon 63 participants Est. completion 2009-01 1 site Stand-aloneOther conditions: Amyotrophic Lateral SclerosisView official trial listing → -
Completed NCT NCT00368862
Efficacy Study of Memantine Hydrochloride and Escitalopram for the Treatment of Co-Morbid Depression and Alcoholism.
Not yet reported Finnish Institute for Health and Welfare 80 participants Est. completion 2006-06 1 siteOther conditions: Alcoholism, DepressionView official trial listing → -
Completed NCT NCT00371059
Memantine for Agitation in Dementia
Not yet reported East Kent Hospitals University NHS Foundation Trust 153 participants Est. completion 2009-09 2 sitesOther conditions: DEMENTIAView official trial listing → -
Completed NCT NCT00375778
Parkinson's Disease Evaluated by PET and the Effect of Memantine
Not yet reported University of Aarhus 12 participants Est. completion 2006-09 1 siteOther conditions: Parkinson's DiseaseView official trial listing → -
Completed NCT NCT00401167
Memantine for Agitation and Aggression in Severe Alzheimer's Disease
Not yet reported Sunnybrook Health Sciences Centre 31 participants Est. completion 2010-01 2 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00409721
The Effect of Memantine on Functional Outcomes and Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis (ALS)
Not yet reported University of Alberta 42 participants Est. completion 2010-12 2 sites Stand-aloneOther conditions: Amyotrophic Lateral SclerosisView official trial listing → -
Completed NCT NCT00411398
A 10 Week Open-Label Pilot Study to Evaluate the Effectiveness and Safety of Memantine(Namenda) as Augmentation Therapy in Patients With Generalized Anxiety Disorder
Not yet reported State University of New York - Upstate Medical University 15 participants Est. completion 2010-05 1 site Stand-aloneOther conditions: General Anxiety Disorder, Social Anxiety DisorderView official trial listing → -
Completed NCT NCT00439699
A Pilot Clinical Trial Of Memantine for Essential Tremor
Not yet reported VA Greater Los Angeles Healthcare System 16 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: Essential TremorView official trial listing → -
Terminated NCT NCT00462228
Effect of Namenda on Short Term Memory and Attention in Patients With Mild to Moderate Traumatic Brain Injury
Not yet reported University of Missouri-Columbia 11 participants Est. completion 2010-12 1 site Stand-aloneOther conditions: Traumatic Brain InjuryView official trial listing → -
Completed NCT NCT00469456
Effect of Memantine on Functional Communication in Patients With Alzheimer's Disease
Not yet reported Forest Laboratories 265 participants Est. completion 2008-11 25 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00476008
Delaying the Progression of Driving Impairment in Individuals With Mild Alzheimer's Disease
Not yet reported Florida Atlantic University 60 participants Est. completion 2012-10 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00476242
Memantine as a Supplement to Naltrexone in Treating Heroin Dependence
Not yet reported, Not yet reported New York State Psychiatric Institute 82 participants Est. completion 2011-08 1 site Stand-aloneOther conditions: Opioid Dependence, Heroin DependenceView official trial listing → -
Completed NCT NCT00505167
Memantine Versus Donepezil in Early Stages of Alzheimer's Disease
Not yet reported Hospital Miguel Servet 64 participants Est. completion 2008-12 3 sitesOther conditions: Dementia, Alzheimer TypeView official trial listing → -
Completed NCT NCT00545974
Memantine (10mg BID) for the Frontal and Temporal Subtypes of Frontotemporal Dementia
Not yet reported University of California, San Francisco 81 participants Est. completion 2012-12 9 sites Stand-aloneOther conditions: Frontal Lobe Dementia, Frontotemporal Lobe Dementia, Semantic DementiaView official trial listing → -
Completed NCT NCT00551161
Magnetic Resonance Spectroscopy Study of Memantine in Alzheimer's Disease
Not yet reported Northwell Health 12 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00566852
Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors
Not yet reported Radiation Therapy Oncology Group 554 participants Est. completion 2016-12 235 sites Stand-aloneOther conditions: Cognitive/Functional Effects, Metastatic Cancer, Neurotoxicity, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00584948
Memantine Treatment in Fragile X-Associated Tremor/Ataxia Syndrome
Not yet reported University of California, Davis 94 participants Est. completion 2012-09 2 sites Stand-aloneOther conditions: Fragile X-Associated Tremor/Ataxia Syndrome, Fragile X Premutation CarriersView official trial listing → -
Completed NCT NCT00585169
Memantine Treatment Study of Pathological Gambling
Not yet reported Yale University 29 participants Est. completion 2011-12 2 sites Stand-aloneOther conditions: Pathological GamblingView official trial listing → -
Completed NCT NCT00586066
Memantine and Cognitive Dysfunction in Bipolar Disorder
Not yet reported Massachusetts General Hospital 72 participants Est. completion 2009-12 3 sites Stand-aloneOther conditions: Bipolar DisorderView official trial listing → -
Completed NCT NCT00586573
Open-Label Pilot Study of Namenda in Adult Subjects With ADHD and ADHD NOS
Not yet reported Massachusetts General Hospital 34 participants Est. completion 2009-10 1 site Stand-aloneOther conditions: ADHDView official trial listing → -
Completed NCT NCT00594737
Open Label Pilot Study of the Effects of Memantine on FDG-PET in Frontotemporal Dementia
Not yet reported Tiffany Chow, MD 17 participants Est. completion 2012-06 1 siteOther conditions: Frontotemporal DementiaView official trial listing → -
Completed NCT NCT00624026
Memantine - Communication Study
Not yet reported Merz Pharmaceuticals GmbH 107 participants Est. completion 2008-12 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00630500
Efficacy and Safety of Memantine for Parkinson's Disease Dementia (PDD) and Dementia With Lewy Bodies (DLB)
Not yet reported Helse Stavanger HF 75 participants Est. completion 2009-03 4 sitesOther conditions: Dementia Associated With Parkinson's Disease, Dementia With Lewy BodiesView official trial listing → -
Completed NCT NCT00630955
Family History Study of Alcohol Consumption Using Memantine
Not yet reported Yale University 111 participants Est. completion 2011-08 1 site Stand-aloneAlcohol use disorderView official trial listing → -
Completed NCT NCT00638027
Memantine for Spasticity in MS Patients
Not yet reported University of Rochester 21 participants Est. completion 2009-02 1 site Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Terminated NCT NCT00638833
Memantine Therapy for Multiple Sclerosis
Not yet reported Clinica Universidad de Navarra, Universidad de Navarra 20 participants Est. completion 2008-03 1 siteOther conditions: Multiple SclerosisView official trial listing → -
Completed NCT NCT00640198
Memantine and Intensive Speech-Language Therapy in Aphasia
Not yet reported Gabinete Berthier y Martínez 28 participants Est. completion 2007-11 1 siteCardiovascular disease Other conditions: AphasiaView official trial listing → -
Completed NCT NCT00646204
Namenda (Memantine) for Non-motor Symptoms in Parkinson's Disease
Not yet reported Baylor College of Medicine 40 participants Est. completion 2009-03 1 site Stand-aloneOther conditions: Parkinson's DiseaseView official trial listing → -
Terminated NCT NCT00649220
Memantine and Antipsychotics Use
Not yet reported Merz Pharmaceuticals GmbH 19 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00652457
Study of Memantine to Treat Huntington's Disease
Not yet reported Jody Corey-Bloom, MD, PhD 50 participants Est. completion 2009-10-28 3 sites Stand-aloneOther conditions: Huntington's DiseaseView official trial listing → -
Completed NCT NCT00674219
Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder
Not yet reported University of California, Los Angeles 17 participants Est. completion 2008-01 1 siteOther conditions: Obsessive-Compulsive Disorder, Generalized Anxiety DisorderView official trial listing → -
Status unknown NCT NCT00703430
Memantine on Aggression and Agitation of Alzheimer's Disease (AD)
Not yet reported Peking University 50 participants Est. completion 2014-06 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00757978
Memantine as Adjunctive Therapy for Schizophrenia Negative Symptoms
Not yet reported Hospital de Clinicas de Porto Alegre 22 participants Est. completion 2008-03 1 siteOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT00768261
Corticolimbic Degeneration and Treatment of Dementia
Not yet reported Washington University School of Medicine 39 participants Est. completion 2009-10Other conditions: DementiaView official trial listing → -
Completed NCT NCT00800709
Memantine and Changes of Biological Markers and Brain PET Imaging in Alzheimer's Disease
Not yet reported Shanghai Mental Health Center 26 participants Est. completion 2010-10 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00804271
Memantine and Validation of a New Alzheimer's Disease Scale
Not yet reported Merz Pharmaceuticals GmbH 487 participants Est. completion 2009-11 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00829816
Safety and Tolerability of Dimebon in Patients on Memantine, and Memantine Plus Donepezil
Not yet reported Medivation, Inc. 46 participants Est. completion 2010-08 4 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00830375
Memantine Treatment of Compulsive Buying
Not yet reported University of Minnesota 10 participants Est. completion 2010-08-01 2 sites Stand-aloneOther conditions: Compulsive BuyingView official trial listing → -
Completed NCT NCT00855686
Memantine Versus Placebo in Parkinson's Disease Dementia or Dementia With Lewy Bodies
Not yet reported H. Lundbeck A/S 199 participants Est. completion 2009-01 1 site Stand-aloneOther conditions: Parkinson's Disease Dementia, Dementia With Lewy BodiesView official trial listing → -
Terminated NCT NCT00857233
Safety and Tolerability of Memantine in Moderate to Severe Alzheimer's Disease
Not yet reported H. Lundbeck A/S 297 participants Est. completion 2010-10 33 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT00857649
Efficacy and Safety of Memantine in Moderate to Severe Alzheimer's Disease
Not yet reported H. Lundbeck A/S 369 participants Est. completion 2010-09 23 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00862940
A Clinical Study Evaluating the Effects of Memantine on Brain Atrophy in Patients With Alzheimer's Disease
Not yet reported H. Lundbeck A/S 277 participants Est. completion 2009-04 Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT00866060
Donepezil and Memantine in Moderate to Severe Alzheimer's Disease
Not yet reported King's College London 800 participants Est. completion 2013-06 1 siteOther conditions: Moderate to Severe Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00869505
Study of Memantine Augmentation in Severe Obsessive-Compulsive Disorder
Massachusetts General Hospital 1 siteOther conditions: Obsessive-Compulsive DisorderView official trial listing → -
Completed NCT NCT00872898
Study of Pharmacokinetics, Safety, Efficacy, and Tolerability of Memantine in Children With Autism
Not yet reported Forest Laboratories 124 participants 17 sites Stand-aloneOther conditions: AutismView official trial listing → -
Completed NCT NCT00880685
Memantine in the Treatment of Kleptomania
Not yet reported University of Chicago 12 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: KleptomaniaView official trial listing → -
Terminated NCT NCT00912288
A Phase 3 Efficacy Study Of Dimebon In Patients With Moderate To Severe Alzheimer's Disease
Not yet reported Pfizer 86 participants Est. completion 2010-08 47 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00928954
Cross-over Comparison of Gabapentin and Memantine as Treatment for Acquired Nystagmus
Not yet reported Case Western Reserve University 10 participants Est. completion 2009-05 1 siteOther conditions: NystagmusView official trial listing → -
Completed NCT NCT00933608
Effects of Memantine on Magnetic Resonance (MR) Spectroscopy in Subjects at Risk for Alzheimer's Disease
Not yet reported NYU Langone Health 17 participants Est. completion 2011-09 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00954616
Inappropriate Medications Associated With Anticholinesterase and/or Memantine Treatment in the Elderly
University Hospital, Limoges 636 participants Est. completion 2012-01 6 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00956085
Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder
Not yet reported New York State Psychiatric Institute 12 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: Obsessive-Compulsive DisorderView official trial listing → -
Completed NCT NCT00980408
The Influence of Glutamate on Memory in Humans
Not yet reported University Hospital, Bonn 120 participants Est. completion 2011-08 1 siteOther conditions: Healthy IndividualsView official trial listing → -
Withdrawn NCT NCT00986115
Efficacy and Safety of the Use of Memantine for Preserving Cognition in Adult Patients With Epilepsy
Not yet reported University of California, Davis Est. completion 2012-04 1 siteOther conditions: EpilepsyView official trial listing → -
Withdrawn NCT NCT00988663
The Impact of Memantine on Electroconvulsive Therapy (ECT): Will it Improve Response and Protect Against Cognitive Problems?
Not yet reported Jerrry L Lewis Est. completion 2009-11 1 siteOther conditions: Major Depressive DisorderView official trial listing → -
Completed NCT NCT01020331
Memantine Therapy in Amyotrophic Lateral Sclerosis
Not yet reported Phoenix Neurological Associates, LTD 20 participants Est. completion 2009-10 1 site Stand-aloneOther conditions: Amyotrophic Lateral SclerosisView official trial listing → -
Completed NCT NCT01025466
Exelon Patch and Combination With Memantine Comparative Trial
Not yet reported Inha University Hospital 206 participants Est. completion 2010-04 26 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT01032759
Memantine and Postoperative Pain
Not yet reported Duke University 77 participants Est. completion 2015-01 1 siteOther conditions: PainView official trial listing → -
Completed NCT NCT01038128
An Open Label Trial of Memantine in the Treatment of Bulimia Nervosa and Body Dysmorphic Disorder
Not yet reported Mclean Hospital 5 participants Est. completion 2011-05 1 site Stand-aloneObstructive sleep apnea Other conditions: Body Dysmorphic DisorderView official trial listing → -
Status unknown NCT NCT01041313
Memantine for Post-Operative Pain Control
Not yet reported University of Washington 120 participants Est. completion 2011-09 1 siteOther conditions: Pain, Post-operativeView official trial listing → -
Completed NCT NCT01052662
Memantine-enhanced Buprenorphine Treatment for Opioid-dependent Young Adults
Not yet reported, Not yet reported University of Massachusetts, Worcester 87 participants Est. completion 2013-10 1 site Stand-aloneOther conditions: Opioid DependenceView official trial listing → -
Completed NCT NCT01054599
Does Memantine Improve Verbal Memory Task Performance in Subjects With Partial Epilepsy and Memory Dysfunction?
Not yet reported American Academy of Neurology 29 participants Est. completion 2014-05 3 sites Stand-aloneOther conditions: EpilepsyView official trial listing → -
Completed NCT NCT01074619
Study on Cognitive Disorders of Multiple Sclerosis
Not yet reported University Hospital, Caen 90 participants Est. completion 2011-11 1 site Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Terminated NCT NCT01078844
Memantine in Adult Autism Spectrum Disorder
Not yet reported Johns Hopkins University 4 participants Est. completion 2010-07 1 siteOther conditions: Autism, Asperger's Disorder, Pervasive Developmental Disorder NOSView official trial listing → -
Completed NCT NCT01108029
Study of Memantine for Gait Disorders And Attention Deficit In Parkinson's Disease
Not yet reported University Hospital, Lille 28 participants Est. completion 2010-10 1 siteOther conditions: Parkinson's Disease, Gait Disorders, NeurologicView official trial listing → -
Completed NCT NCT01112683
Efficacy and Safety of Memantine Hydrochloride in Enhancing the Cognitive Abilities of Young Adults With Down Syndrome
Not yet reported University of Colorado, Denver 42 participants Est. completion 2011-08 1 site Stand-aloneOther conditions: Down SyndromeView official trial listing → -
Completed NCT NCT01188148
Series Studies of Bipolar Disorder-Valproate add-on Memantine
Not yet reported, Not yet reported National Cheng-Kung University Hospital 219 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: Bipolar DisordersView official trial listing → -
Completed NCT NCT01188525
Pharmacokinetic Study to Characterize Individual Metabolic Profile
Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 10 participants Est. completion 2011-07 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT01189214
Psychopharmacotherapy in Multiple Substances Abuse
Not yet reported National Cheng-Kung University Hospital 200 participants Est. completion 2011-06 1 site Stand-aloneOther conditions: Substance AbuseView official trial listing → -
Completed NCT NCT01196065
A Study of the Effect of Memantine on Pharmacokinetics, Safety and Tolerability of Single Dose RO5313534 in Healthy Volunteers, and the Effect of RO5313534 on Safety and Tolerability of Steady State Memantine
Not yet reported Hoffmann-La Roche 16 participants Est. completion 2010-11 1 site Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Terminated NCT NCT01260467
Memantine for Recurrent Glioblastoma
Not yet reported University of Rochester 4 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: GlioblastomaView official trial listing → -
Completed NCT NCT01261741
Investigation of Memantine in the Treatment of Memory, Concentration or Attention Problems
Not yet reported Merz Pharmaceuticals GmbH 299 participants Est. completion 2011-09 14 sites Stand-aloneOther conditions: Memory Disorder, Retention Disorder, Cognitive, Subjective Cognitive Impairment, Memory, Concentration or Attention ProblemsView official trial listing → -
Completed NCT NCT01333865
A Study of Memantine Hydrochloride (Namenda®) for Cognitive and Behavioral Impairment in Adults With Autism Spectrum Disorders
Not yet reported Massachusetts General Hospital 25 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: Autism Spectrum DisordersView official trial listing → -
Terminated NCT NCT01362686
Comparative Research of Alzheimer's Disease Drugs
Not yet reported Indiana University 200 participants Est. completion 2015-10 5 sites Stand-aloneOther conditions: Dementia, Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01364818
Brain Connectivity in Neurodevelopmental Disorders in Response to Treatment
University of North Carolina, Chapel Hill 25 participants Est. completion 2014-12 1 siteOther conditions: Autism Spectrum Disorders, Psychosis, Fragile X SyndromeView official trial listing → -
Completed NCT NCT01372449
A Multi-site Double-blind Placebo-controlled Trial of Memantine Versus Placebo in Children With Autism (MEM)
Not yet reported Evdokia Anagnostou 23 participants Est. completion 2015-10 2 sitesOther conditions: Autism Spectrum DisorderView official trial listing → -
Completed NCT NCT01392287
Treatment Resistant Geriatric Depression in Primary Care
Not yet reported Mclean Hospital 12 participants Est. completion 2012-04 1 site Stand-aloneOther conditions: Major Depressive DisorderView official trial listing → -
Completed NCT NCT01409694
Alzheimer's Disease - Input of Vitamin D With mEmantine Assay
Not yet reported University Hospital, Angers 90 participants Est. completion 2016-01 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Terminated NCT NCT01430351
Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy
Not yet reported M.D. Anderson Cancer Center 144 participants Est. completion 2025-02-02 1 site Stand-aloneObstructive sleep apnea Other conditions: Glioblastoma, Supratentorial GlioblastomaView official trial listing → -
Completed NCT NCT01458470
A Trial of Memantine as Symptomatic Treatment for Early Huntington Disease
Not yet reported University of British Columbia 19 participants Est. completion 2012-11 1 siteOther conditions: Huntington DiseaseView official trial listing → -
Completed NCT NCT01461174
Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Deprivation Challenge in Healthy Volunteers
Not yet reported Qualissima 36 participants Est. completion 2014-11 2 sites Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01519063
Naltrexone and Memantine Effects on Alcohol Drinking Behaviors
Not yet reported Yale University 75 participants Est. completion 2017-05-01 1 site Stand-aloneAlcohol use disorderView official trial listing → -
Completed NCT NCT01533493
Memantine for Executive Dysfunction in Adults With ADHD: A Pilot Study
Not yet reported Massachusetts General Hospital 33 participants Est. completion 2013-08 1 siteOther conditions: Attention Deficit Hyperactivity Disorder (ADHD), Executive Function Deficits (EFD)View official trial listing → -
Completed NCT NCT01535040
Memantine Hydrochloride in Helping Cancer Survivors Stop Smoking
Not yet reported Wake Forest University Health Sciences 130 participants Est. completion 2014-02-01 1 siteOther conditions: Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer, Tobacco Use DisorderView official trial listing → -
Completed NCT NCT01536314
Prophylaxis of Neuropathic Pain by mémantine
Not yet reported University Hospital, Clermont-Ferrand 43 participants Est. completion 2013-11 1 siteOther conditions: Neuropathic PainView official trial listing → -
Completed NCT NCT01555697
Biomarker Strategies for Medication-Enhanced Cognitive Training in Schizophrenia
Not yet reported, Not yet reported University of California, San Diego 80 participants Est. completion 2019-06-01 1 siteOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT01585168
Functional Neuroimaging of Alcoholism Vulnerability (PIT)
Not yet reported Yale University 71 participants Est. completion 2016-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01592747
Withdrawal Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified Previously Treated With Memantine
Not yet reported Forest Laboratories 479 participants Est. completion 2013-10 94 sites Stand-aloneOther conditions: Autistic Disorder, Autism, Asperger's Disorder, Asperger Syndrome, Autism Spectrum Disorders, Pervasive Developmental Disorder - Not Otherwise Specified (PDD-NOS)View official trial listing → -
Terminated NCT NCT01592773
Safety Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)
Not yet reported Forest Laboratories 747 participants Est. completion 2014-03 106 sites Stand-aloneOther conditions: Autism Spectrum Disorder (ASD), Autism, Autistic Disorder, Asperger's Disorder, Asperger's, Pediatric Autism, Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)View official trial listing → -
Completed NCT NCT01592786
An Open-Label Safety Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)
Not yet reported Forest Laboratories 906 participants Est. completion 2013-08 118 sites Stand-aloneOther conditions: Autism Spectrum Disorder (ASD), Autism, Autistic Disorder, Asperger's Disorder, Asperger's, Pediatric Autism, Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)View official trial listing → -
Completed NCT NCT01602185
Study of NMDA Antagonists and Neuropathic Pain
Not yet reported University Hospital, Clermont-Ferrand 7 participants Est. completion 2016-09-07 1 site Stand-aloneOther conditions: Neuropathic PainView official trial listing → -
Terminated NCT NCT01626391
Safety Study of TRx0237 in Patients Already Taking Medications for Mild and Moderate Alzheimer's Disease
Not yet reported TauRx Therapeutics Ltd 9 participants Est. completion 2013-03 12 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT01653457
Randomised Controlled Trial of Memantine in Fibromyalgia
Not yet reported Aragon Institute of Health Sciences 60 participants Est. completion 2013-05 1 siteOther conditions: FibromyalgiaView official trial listing → -
Completed NCT NCT01656187
Attenuation of Corticosteroid Induced Hippocampal Changes
Not yet reported University of Texas Southwestern Medical Center 46 participants Est. completion 2017-01 1 site Stand-aloneOther conditions: Organic Memory ImpairmentView official trial listing → -
Completed NCT NCT01677754
A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease Therapy
Not yet reported Hoffmann-La Roche 542 participants Est. completion 2015-06-12 142 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT01696591
The Long-Term Safety and Efficacy Follow-Up Study of Subjects Who Completed the Phase I Clinical Trial of Neurostem®-AD
Duk Lyul Na 14 participants Est. completion 2013-09 1 siteOther conditions: Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Delirium, Dementia, Amnestic, Cognitive Disorders, Mental DisordersView official trial listing → -
Completed NCT NCT01744444
Treatment of Pendular Nystagmus With Gabapentin and Memantine in Patients With Multiple Sclerosis
Not yet reported Hospices Civils de Lyon 10 participants Est. completion 2013-07 1 site Stand-aloneOther conditions: Pendular Nystagmus Patients With Multiple SclerosisView official trial listing → -
Withdrawn NCT NCT01844427
Memantine Monotherapy for Executive Dysfunction and ADHD
Not yet reported Massachusetts General HospitalOther conditions: ADHD, Executive Function Deficits (EFD's)View official trial listing → -
Status unknown NCT NCT01849042
Effect of Memantine Oral Pump on Language in Patients With Probable Alzheimer's Disease
Not yet reported Konkuk University Medical Center 188 participants Est. completion 2015-08 1 siteOther conditions: Alzheimer's Disease, DementiaView official trial listing → -
Completed NCT NCT01872598
Masitinib in Patients With Mild to Moderate Alzheimer's Disease
Not yet reported AB Science 721 participants Est. completion 2020-12 6 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT01876823
Memantine Plus Es-citalopram in Elderly Depressed Patients With Cognitive Impairment
Not yet reported, Not yet reported New York State Psychiatric Institute 60 participants Est. completion 2010-03 1 site Stand-aloneOther conditions: Mild Cognitive Impairment, Major Depressive Disorder, Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01902004
Brain Aging and Treatment Response in Geriatric Depression
Not yet reported University of California, Los Angeles 115 participants Est. completion 2019-01-23 1 siteOther conditions: Mild Cognitive Impairment (MCI), DepressionView official trial listing → -
Completed NCT NCT01921972
The Efficacy of a Combination Regimen in Patients With Mild to Moderate Probable Alzheimer's Disease
Not yet reported Charite University, Berlin, Germany 232 participants Est. completion 2009-05 Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01972074
Behavioral and Neural Response to Memantine in Adolescents With Autism Spectrum Disorder
Not yet reported Massachusetts General Hospital 84 participants Est. completion 2018-05-07 1 site Stand-aloneOther conditions: Autism Spectrum DisorderView official trial listing → -
Completed NCT NCT01999894
Open-label Study of Safety and Tolerability of Memantine in Children With Autism
Not yet reported Forest Laboratories 102 participants Est. completion 2013-02 19 sites Stand-aloneOther conditions: Autism, Pediatric AutismView official trial listing → -
Status unknown NCT NCT02001103
Memantine add-on for Cognitive and Negative Symptoms of Schizophrenia
Not yet reported National Taiwan University Hospital 120 participants Est. completion 2017-12 1 siteOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT02001584
A Study to Examine the, Safety, Tolerability and Pharmacokinetics Co-Administered Baclofen and Memantine in Obese and Lean, Otherwise Healthy Adults
Not yet reported Gedeon Richter Plc. Est. completion 2014-05 1 site Stand-aloneOther conditions: Healthy Volunteers;, Obese, Otherwise Healthy VolunteersView official trial listing → -
Completed NCT NCT02079246
Long-term Safety and Tolerability of Idalopirdine (Lu AE58054) as Adjunctive Treatment to Donepezil in Patients With Mild-moderate Alzheimer's Disease
Not yet reported H. Lundbeck A/S 1463 participants Est. completion 2017-07-06 258 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT02080364
Evaluation of the Efficacy and Safety of Azeliragon (TTP488) in Patients With Mild Alzheimer's Disease
Not yet reported vTv Therapeutics 880 participants Est. completion 2018-06-01 115 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02118727
Therapy in Amyotrophic Lateral Sclerosis (TAME)
Not yet reported University of Kansas Medical Center 89 participants Est. completion 2021-07-22 13 sitesOther conditions: Amyotrophic Lateral Sclerosis, Frontal Temporal DementiaView official trial listing → -
Status unknown NCT NCT02136823
Impact of Persistent Conductances on Motor Unit Firing in SCI
Not yet reported Shirley Ryan AbilityLab 50 participants Stand-aloneOther conditions: Chronic Spinal Cord InjuryView official trial listing → -
Active, not recruiting NCT NCT02144584
Memantine for Enhanced Stroke Recovery
Not yet reported University of Utah 20 participants Est. completion 2027-06 1 siteCardiovascular disease Other conditions: Upper Extremity WeaknessView official trial listing → -
Completed NCT NCT02162251
Post-marketing Surveillance of Donepezil Hydrochloride Investigation of the Safety and Effectiveness of Combination Therapy of Donepezil Hydrochloride and Memantine Hydrochloride in Patients With Alzheimer's Disease
Eisai Co., Ltd. 3482 participants Est. completion 2016-04-15 1 siteOther conditions: Alzheimer's DeseaseView official trial listing → -
Status unknown NCT NCT02233556
Effect of Memantine on ERP in Early Schizophrenia and Healthy Subjects
Not yet reported National Taiwan University Hospital 20 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: SchizophreniaView official trial listing → -
Terminated NCT NCT02234752
Galantamine and Memantine Combination for Cognitive Impairments in Schizophrenia
Not yet reported Sheppard Pratt Health System 3 participants Est. completion 2016-07 1 site Stand-aloneOther conditions: Schizophrenia, Schizoaffective DisorderView official trial listing → -
Completed NCT NCT02240589
Memantine for Neuroprotection and Cognitive Enhancement Following Traumatic Brain Injury
Not yet reported Indiana University 11 participants Est. completion 2016-04 1 site Stand-aloneOther conditions: Traumatic Brain InjuryView official trial listing → -
Withdrawn NCT NCT02246075
Study of the Safety of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease Currently Receiving Memantine
Not yet reported FORUM Pharmaceuticals Inc 2 sitesOther conditions: Alzheimer's Disease, Dementia, CognitionView official trial listing → -
Completed NCT NCT02258828
An Open-Label Trial of Memantine for Cognitive Impairment in Patients With Post-Traumatic Stress Disorder
Not yet reported Sriram Ramaswamy 26 participants Est. completion 2007-03 1 site Stand-aloneOther conditions: PTSDView official trial listing → -
Terminated NCT NCT02288000
Prediction of Cognitive Properties of Memantine for Neurodegenerative Diseases
Not yet reported University Hospital, Lille 30 participants Est. completion 2020-12-31 3 sitesOther conditions: Alzheimer Disease, BatteryView official trial listing → -
Completed NCT NCT02304302
Down Syndrome Memantine Follow-up Study
Not yet reported University Hospitals Cleveland Medical Center 160 participants Est. completion 2020-07-22 2 sites Stand-aloneOther conditions: Down Syndrome, Intellectual DisabilityView official trial listing → -
Withdrawn NCT NCT02353130
Cortical Metrics Assessment Outcome Measure Development in Autism With Memantine Treatment
University of North Carolina, Chapel Hill Est. completion 2015-12Other conditions: Autism Spectrum DisordersView official trial listing → -
Completed NCT NCT02360215
Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases
Not yet reported NRG Oncology 518 participants Est. completion 2019-08-26 220 sites Stand-aloneOther conditions: Cognitive Impairment, Metastatic Malignant Neoplasm in the Brain, Solid NeoplasmView official trial listing → -
Terminated NCT NCT02374567
Pharmacovigilance in Gerontopsychiatric Patients
Not yet reported Hannover Medical School 407 participants Est. completion 2017-06-28 5 sites Stand-aloneOther conditions: Dementia, Depression, Schizophrenia, Psychosomatic Disorders, Anxiety DisordersView official trial listing → -
Completed NCT NCT02466191
Treatment of Pendular Nystagmus in OPT
Not yet reported Hospices Civils de Lyon 7 participants Est. completion 2016-01 1 site Stand-aloneOther conditions: Pendular Nystagmus, Oculopalatal TremorView official trial listing → -
Completed NCT NCT02467556
Psychological Intervention and Physiotherapy With Medication Improves CRPS Patients Outcome
Not yet reported Helsinki University Central Hospital 10 participants Est. completion 2014-06 1 siteOther conditions: CRPSView official trial listing → -
Completed NCT NCT02535611
Evaluation of Memantine Versus Placebo on Ischemic Stroke Outcome
Not yet reported Mazandaran University of Medical Sciences 47 participants Est. completion 2017-09Cardiovascular disease Other conditions: Excitotoxicity, MemantineView official trial listing → -
Completed NCT NCT02553928
Comparison of Once Daily and Twice Daily Dosing on Safety and Tolerability of Memantine in Patients With Alzheimer
Not yet reported H. Lundbeck A/S 62 participants Est. completion 2016-07 6 sites Stand-aloneOther conditions: Alzheimer Dementia (AD)View official trial listing → -
Completed NCT NCT02570581
MELA Study - Hedonic Study on the Taste of Drugs Crushed in Food: Observational Study Involving 16 Healthy Volunteers
Not yet reported Centre Hospitalier Universitaire de Nice 16 participants Est. completion 2014-07 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02580305
SUVN-502 With Donepezil and Memantine for the Treatment of Moderate Alzheimer's Disease- Phase 2a Study
Not yet reported Suven Life Sciences Limited 564 participants Est. completion 2019-11-07 71 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02615847
Clinical Trial to Study the Safety and Tolerability of Memantin Mepha® in Sickle Cell Disease Patients
Not yet reported University of Zurich 9 participants Est. completion 2017-07 1 siteOther conditions: Sickle Cell DiseaseView official trial listing → -
Status unknown NCT NCT02630888
Efficacy of Memantine add-on in the Treatment of Bipolar Disorder (Type I) Nonresponders or Partial Responders Patients
Not yet reported University of Sao Paulo 44 participants Est. completion 2020-09 1 siteOther conditions: Bipolar DisorderView official trial listing → -
Enrolling by invitation NCT NCT02670161
Quality Improvement and Practice Based Research in Neurology Using the EMR
Not yet reported Endeavor Health 3300 participants Est. completion 2027-12 1 siteCardiovascular disease Other conditions: Brain Tumors, Epilepsy, Migraine, Mild Cognitive Impairment, Concussion, Multiple Sclerosis, Neuropathy, Parkinson's, Restless Legs SyndromeView official trial listing → -
Completed NCT NCT02811627
Predicting Treatment Response to Memantine in Autism Using Magnetic Resonance Spectroscopy
Not yet reported University of Missouri-Columbia 10 participants Est. completion 2021-04 1 site Stand-aloneOther conditions: Autism Spectrum DisorderView official trial listing → -
Completed NCT NCT02854917
Memantine and Comprehensive, Individualized, Patient Centered Management of Alzheimer's Disease: Health Outcome
NYU Langone Health 20 participants Est. completion 2018-01-05 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT02860338
COMPARATIVE EFFECTIVENESS OF MCI and DEMENTIA TREATMENTS IN A COMMUNITY-BASED DEMENTIA PRACTICE
Clionsky Neuro Systems Inc. 900 participants Est. completion 2015-12Other conditions: Mild Cognitive Impairment, Dementia, Hypoxia, Hyperhomocysteinemia, Vitamin B 12 Deficiency, Iron Deficiency, Anemia, TBI, Neurodegenerative Disorders, Alzheimer's Disease, Vascular Dementia, Brain Injuries, Tauopathies, Parkinson's Disease, Lewy Body Dementia, Frontotemporal Dementia, TDP-43 ProteinopathiesView official trial listing → -
Terminated NCT NCT02950233
Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial
Not yet reported Population Health Research Institute 27 participants Est. completion 2019-03-31 2 sites Stand-aloneOther conditions: Pain, PostoperativeView official trial listing → -
Status unknown NCT NCT03038035
The Alzheimer's Disease THErapy With NEuroaid (ATHENE) Study
Not yet reported National University Hospital, Singapore 150 participants Est. completion 2019-06 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT03039842
Combination of Dextromethorphan and Memantine in Treating Bipolar Disorder
Not yet reported National Cheng-Kung University Hospital 300 participants Est. completion 2017-12-31 1 site Stand-aloneOther conditions: Bipolar Disorder IIView official trial listing → -
Status unknown NCT NCT03043001
Memantine in Bipolar Patients With Alcoholism
Not yet reported National Cheng-Kung University Hospital 60 participants Est. completion 2017-12-31 1 siteOther conditions: AOD Effects and ConsequencesView official trial listing → -
Completed NCT NCT03121820
Fasting Bioequivalence Study of Memantinol 20 mg Tablets Versus Akatinol Memantine® 20 mg Tablets In Normal Healthy Subjects
Not yet reported Geropharm 18 participants Est. completion 2016-11-19 1 site Stand-aloneOther conditions: Bioequivalence, AUC, Cmax, PharmacokineticsView official trial listing → -
Status unknown NCT NCT03168997
Memantine Treatment in Alzheimer's Disease Patients
Not yet reported Wei Cuibai 222 participants Est. completion 2018-12-31Other conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03194906
Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors
Not yet reported St. Jude Children's Research Hospital 41 participants Est. completion 2023-06-28 1 siteOther conditions: Glioma of Brain, Craniopharyngioma, Ependymoma, Germ Cell TumorView official trial listing → -
Completed NCT NCT03221894
A Retrospective Study to Investigate the Additive Effectiveness of Chinese Herbal Medicine in Alzheimer's Disease
Dongzhimen Hospital, Beijing 120 participants Est. completion 2021-07-31 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT03247218
A Phase - IIa - IIb, Trial to Study the Safety, Tolerability and Efficacy of Memantine as a Long-term Treatment of SCD
Not yet reported HaEmek Medical Center, Israel 40 participants Est. completion 2020-12-31 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Withdrawn NCT NCT03316898
A FDG-PET Study of AGN-242071 Added to Standard-of-Care (Donepezil ± Memantine) for the Treatment of Participants With Mild to Moderate Alzheimer's Disease
Not yet reported Allergan Est. completion 2018-11-04 6 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT03342443
Effect of Memantine on Radiotherapy-related Cognitive Impairment
Not yet reported, Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 240 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Cognitive ImpairmentView official trial listing → -
Terminated NCT NCT03468543
Study Determining Gastric-Retentive and Modified Release Properties of Prototype Capsules in Healthy Subjects
Not yet reported Lyndra Inc. 3 participants Est. completion 2017-09-18 1 site Stand-aloneOther conditions: Gastric Retention, HealthyView official trial listing → -
Completed NCT NCT03527472
Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus
Not yet reported Vanderbilt University Medical Center 111 participants Est. completion 2026-02-28 3 sites Stand-aloneOther conditions: Lupus Erythematosus, SystemicView official trial listing → -
Terminated NCT NCT03553875
Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions
Not yet reported Massachusetts General Hospital 25 participants Est. completion 2025-11-25 1 siteOther conditions: Autism, Autism Spectrum Disorder, Nonverbal Learning DisabilityView official trial listing → -
Completed NCT NCT03560245
A Study of Bryostatin in Moderately Severe to Severe Alzheimer's Disease Subjects Not On Memantine
Not yet reported Neurotrope Bioscience, Inc. 108 participants Est. completion 2019-07-25 28 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03565809
Quality of the Management of Diabetes in Elderly People With Dementia in France
University Hospital, Toulouse 87816 participants Est. completion 2018-12-31 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03569579
CKD-355 Drug-drug Interaction Study (CKD-355 DDI P1)
Not yet reported Chong Kun Dang Pharmaceutical 20 participants Est. completion 2018-06-04 1 site Stand-aloneOther conditions: Central Nervous System DiseasesView official trial listing → -
Completed NCT NCT03670095
Study in Healthy Subjects to Compare Two Tablet Formulations of Memantine (Ebixa®) in Fasted and Fed Conditions
Not yet reported H. Lundbeck A/S 64 participants Est. completion 2018-12-24 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT03686774
Memantine and Post-mastectomy Neuropathic Pain
Not yet reported University Hospital, Clermont-Ferrand 150 participants Est. completion 2022-01-31 1 site Stand-aloneOther conditions: Neuropathic PainView official trial listing → -
Completed NCT NCT03703856
Biomarker Predictors of Memantine Sensitivity in Patients With Alzheimer's Disease
Not yet reported University of California, San Diego 53 participants Est. completion 2025-12-30 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03709888
Memantine XR and Pregabalin for Chemotherapy-Induced Peripheral Neuropathy
Saint John's Cancer Institute 20 participants Est. completion 2021-04-29 1 siteOther conditions: Chemotherapy-induced Peripheral NeuropathyView official trial listing → -
Completed NCT NCT03711825
Study to Evaluate Safety/Duration in Stomach of Extended Release Capsules Containing Memantine Hydrochloride in Healthy Adults
Not yet reported Lyndra Inc. 8 participants Est. completion 2018-11-13 1 site Stand-aloneOther conditions: Alzheimer Disease, Gastric Retention, HealthyView official trial listing → -
Completed NCT NCT03729128
Add-on Low Dose Dextromethorphan and Memantine in Patients With Amphetamine-type Stimulants Use Disorder
Not yet reported, Not yet reported Tzu-Yun Wang 85 participants Est. completion 2020-08-31 1 site Stand-aloneOther conditions: Stimulants Use DisorderView official trial listing → -
Completed NCT NCT03779672
Memantine for Epileptic Encephalopathy
Not yet reported Kenneth Myers, MD 30 participants Est. completion 2022-02-08 1 siteOther conditions: Epileptic Encephalopathy, Childhood-OnsetView official trial listing → -
Completed NCT NCT03802162
A Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-355
Not yet reported Chong Kun Dang Pharmaceutical 60 participants Est. completion 2019-08-31 1 site Stand-aloneOther conditions: Alzheimer's Disease (AD)View official trial listing → -
Status unknown NCT NCT03858270
Inhibition of α-synuclein Cell-cell Transmission by NMDAR Blocker, Memantine
Not yet reported Wayne State University 50 participants Est. completion 2023-07-01 1 site Stand-aloneOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT03860597
Memantine Effects on Sensorimotor Gating and Neurocognition in Schizophrenia
Not yet reported University of California, San Diego 42 participants Est. completion 2021-03-31 1 siteOther conditions: Schizophrenia, Schizo Affective Disorder, Schizoaffective Disorder, HealthyView official trial listing → -
Completed NCT NCT03918616
P2X7 Receptor, Inflammation and Neurodegenerative Diseases
University of Pisa 50 participants Est. completion 2019-03-30 1 siteOther conditions: Neuro-Degenerative DiseaseView official trial listing → -
Status unknown NCT NCT03954613
Evaluation of the Contribution of Regular Cognitive Exercises to Treatment in Patients With Alzheimer's Disease
Not yet reported Neutec Ar-Ge San ve Tic A.Ş 198 participants Est. completion 2024-03-01 1 siteOther conditions: Alzheimer Disease, Cognitive ChangeView official trial listing → -
Status unknown NCT NCT03959124
Deep Brain Stimulation for Alzheimer's Disease
Not yet reported Buddhist Tzu Chi General Hospital 30 participants Est. completion 2021-09-30 1 site Stand-aloneOther conditions: Alzheimer Disease, Dementia, Alzheimer Type, Deep Brain StimulationView official trial listing → -
Completed NCT NCT03986424
Local Study of Akatinol Memantine in VaD in Russia
Not yet reported Merz Pharmaceuticals GmbH 130 participants Est. completion 2022-06-01 4 sites Stand-aloneOther conditions: Vascular DementiaView official trial listing → -
Completed NCT NCT03988803
A Study in Healthy Men and Women to Test Which Effects Memantine and BI 425809 Have on Each Other
Not yet reported Boehringer Ingelheim 16 participants Est. completion 2019-10-30 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT04033419
Memantine for Prevention of Cognitive Decline in Patients With Breast Cancer
Not yet reported UNC Lineberger Comprehensive Cancer Center 55 participants Est. completion 2022-04-04 1 site Stand-aloneOther conditions: Cognitive Decline, Chemo-brainView official trial listing → -
Status unknown NCT NCT04035798
add-on Low Dose Memantine in Middle-to-old Aged Bipolar II Disorder Patients
Not yet reported, Not yet reported National Cheng-Kung University Hospital 120 participants Est. completion 2022-07-31 1 site Stand-aloneOther conditions: Bipolar II DisorderView official trial listing → -
Completed NCT NCT04117178
Monitoring Anti-Dementia Drugs by Serum Levels
Not yet reported Zealand University Hospital 132 participants Est. completion 2023-02-16 1 site Stand-aloneOther conditions: Dementia, Dementia With Lewy Bodies, Dementia in Parkinsons Disease, Dementia Alzheimers, Alzheimer DiseaseView official trial listing → -
Completed NCT NCT04217694
Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
Not yet reported Mayo Clinic 18 participants Est. completion 2024-08-12 1 site Stand-aloneOther conditions: Malignant Central Nervous System Neoplasm, Primary Central Nervous System NeoplasmView official trial listing → -
Completed NCT NCT04417543
Effect of Memantine on Cognitive Impairment in Patients With Epilepsy
Not yet reported Assiut University 100 participants Est. completion 2020-01-15 1 siteOther conditions: EpilepsyView official trial listing → -
Completed NCT NCT04538066
Bryostatin Treatment of Moderately Severe Alzheimer's Disease
Not yet reported Neurotrope Bioscience, Inc. 122 participants Est. completion 2022-11-16 19 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Terminated NCT NCT04588246
Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery
Not yet reported NRG Oncology 19 participants Est. completion 2024-08-06 81 sites Stand-aloneOther conditions: Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Breast Neoplasm, Metastatic Malignant Digestive System Neoplasm, Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm, Metastatic Melanoma, Metastatic Renal Cell Carcinoma, Recurrent Brain Neoplasm, Stage IV Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8View official trial listing → -
Status unknown NCT NCT04687566
Dextromethorphan, Memantine Monotherapy, or Combined Use of Dextromethorphan and Memantine in Amphetamine Addiction
Not yet reported, Not yet reported National Cheng-Kung University Hospital 120 participants Est. completion 2024-07-31 1 site Stand-aloneOther conditions: Amphetamine Addiction, PharmacotherapyView official trial listing → -
Completed NCT NCT04698525
Comparative Study Between Valproate and Memantine in the Prophylactic Management of Episodic Migraine.
Not yet reported Universidad Autonoma de San Luis Potosí 33 participants Est. completion 2020-01-15 1 siteOther conditions: Migraine HeadacheView official trial listing → -
Status unknown NCT NCT04737967
The Potential Protective Role of Venlafaxine Versus Memantine in Paclitaxel Induced Peripheral Neuropathy
Not yet reported, Not yet reported Mendel AI 60 participants Est. completion 2021-10-01 1 site Stand-aloneOther conditions: Oncology Pain, Chemotherapy-induced Peripheral NeuropathyView official trial listing → -
Completed NCT NCT04792645
Memantine in Body Focused Repetitive Behaviors
Not yet reported University of Chicago 100 participants Est. completion 2022-07-08 1 site Stand-aloneOther conditions: Trichotillomania (Hair-Pulling Disorder), DermatillomaniaView official trial listing → -
Status unknown NCT NCT04801342
Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain Metastases
Not yet reported National Taiwan University Hospital 72 participants Est. completion 2025-02-28 1 site Stand-aloneOther conditions: Metastatic Malignant Neoplasm to BrainView official trial listing → -
Active, not recruiting NCT NCT04804644
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability
Not yet reported NRG Oncology 152 participants Est. completion 2031-07-01 231 sitesOther conditions: Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Recurrent Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8View official trial listing → -
Completed NCT NCT04857983
Memantine Augmentation of Targeted Cognitive Training in Schizophrenia
Not yet reported, Not yet reported University of California, San Diego 62 participants Est. completion 2025-03-30 1 siteOther conditions: Schizophrenia, Schizoaffective DisorderView official trial listing → -
Active, not recruiting NCT NCT04939597
A Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for a Brain Tumor
Not yet reported Children's Oncology Group 162 participants Est. completion 2027-09-30 138 sites Stand-aloneOther conditions: Central Nervous System CarcinomaView official trial listing → -
Withdrawn NCT NCT04966546
Targeting Spreading Depolarization After Chronic Subdural Hematoma Surgery (TASD)
Not yet reported University of New Mexico Est. completion 2025-12-01 1 site Stand-aloneOther conditions: Chronic Subdural HematomaView official trial listing → -
Status unknown NCT NCT05015595
Memantine for Refractory OCD Patients
Not yet reported University of Roma La Sapienza 20 participants Est. completion 2022-12-31Other conditions: Obsessive-Compulsive DisorderView official trial listing → -
Active, not recruiting NCT NCT05063851
The Use of Memantine for Prevention of Alzheimer's Disease
Not yet reported University of Virginia 32 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT05102045
The Effects of Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer's Disease
Not yet reported Istanbul Medipol University Hospital 27 participants Est. completion 2017-06-01 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT05321680
Withdrawal of Antidementia Drugs in Advanced Dementia (WADAD)
Not yet reported Centro Hospitalar De São João, E.P.E. 16 participants Est. completion 2022-03-20 1 site Stand-aloneOther conditions: DementiaView official trial listing → -
Active, not recruiting NCT NCT05418049
Evaluating the Neurophysiologic and Clinical Effects of Single Dose Drug Challenge
Not yet reported Children's Hospital Medical Center, Cincinnati 45 participants Est. completion 2026-03-05 1 site Stand-aloneOther conditions: Fragile X SyndromeView official trial listing → -
Status unknown NCT NCT05430867
Efficacy and Safety of Memantine and Sodium Oligomannate in Patients With Moderate to Severe Alzheimer's Disease
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 150 participants Est. completion 2024-12-31 Stand-aloneOther conditions: Treatment, Efficacy, Safety, Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT05531383
Effect of Early Memantine Administration on Outcome of Patients With Moderate to Severe Traumatic Brain Injury
Not yet reported Minia University 70 participants Est. completion 2024-07-09 1 siteOther conditions: Traumatic Brain InjuryView official trial listing → -
Status unknown NCT NCT05532644
Correlation of P-glycoprotein Polymorphisms With Microbial Metabolites in Patients With Alzheimer's Disease on Medication
Aristotle University Of Thessaloniki 135 participants Est. completion 2024-09 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT05538507
Efficacy of Chinese Traditional Medicine "Smart Soup" in Cognition and Behavior Regulation in Alzheimer's Disease
Not yet reported Peking Union Medical College Hospital 180 participants Est. completion 2024-06 1 siteOther conditions: Alzheimer Disease, Mild Cognitive ImpairmentView official trial listing → -
Not yet recruiting NCT NCT05564169
Masitinib in Patients With Mild Alzheimer's Disease
Not yet reported AB Science 600 participants Est. completion 2029-12 9 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT05647473
Efficacy, Safety and Response Predictors of Adjuvant Astragalus for Cognition in Orthostatic Hypotension
Not yet reported Fujian Medical University Union Hospital 66 participants Est. completion 2025-05-30 1 site Stand-aloneOther conditions: Orthostatic Hypotension, Alzheimer DiseaseView official trial listing → -
Active, not recruiting NCT NCT05796752
Behavioral Treatment and Memantine in Body Focused Repetitive Behaviors
Not yet reported, Not yet reported University of Chicago 26 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Skin-Picking, Trichotillomania (Hair-Pulling Disorder)View official trial listing → -
Completed NCT NCT05804279
Pharmacokinetics of BPDO-1603 or BPDO-16031 and BPDO-16033 Administration in Healthy Adults
Not yet reported Hyundai Pharm 24 participants Est. completion 2023-03-14 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT05807165
HF-SRT vs. HS-WBRT in Treating Patients With Brain Oligometastases
Chang Gung Memorial Hospital 115 participants Est. completion 2026-07-31 1 siteOther conditions: Brain OligometastasesView official trial listing → -
Status unknown NCT NCT05834231
Efficacy of Memantine in Prevention of Oxaliplatin-induced Peripheral Neurotoxicity
Not yet reported, Not yet reported Mansoura University 60 participants Est. completion 2024-10Other conditions: CancerView official trial listing → -
Completed NCT NCT06337994
Memantine Hydrochloride for Treatment of Cognitive Dysfunction Due to Traumatic Brain Injury
Not yet reported Assiut University 60 participants Est. completion 2024-08-01 1 siteOther conditions: Treatment of Cognitive Deficits After Traumatic Brain InjuryView official trial listing → -
Completed NCT NCT06501638
Efficacy and Safety of memanTine in the Treatment Of Frequently symPtomatic Atrial Premature Beats
Not yet reported Shanghai East Hospital 256 participants Est. completion 2025-05-16 1 site Stand-aloneOther conditions: Atrial Premature Beats, Contractions, or SystolesView official trial listing → -
Not yet recruiting NCT NCT06594172
Early Application of Memantine and Pioglitazone to Protect Cognitive Function After Radiotherapy
Not yet reported Affiliated Cancer Hospital & Institute of Guangzhou Medical University 67 participants Est. completion 2027-06-30 Stand-aloneOther conditions: Radiation Disease, Cognitive Impairment, Drug EffectView official trial listing → -
Not yet recruiting NCT NCT06914310
Memantine as an Additive Therapy in Patients With Traumatic Brain Injury
Not yet reported, Not yet reported Mansoura University 80 participants Est. completion 2025-11-30 1 siteOther conditions: Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury (TBI)View official trial listing → -
Not yet recruiting NCT NCT07164794
Memantine Hydrochloride in Prostate Cancer Patients
Not yet reported Bin Xu 15 participants Est. completion 2028-06 Stand-aloneOther conditions: Metastatic Castration-resistant Prostate Cancer (mCRPC), Prostate Cancer, Neuroendocrine Prostate Cancer (NEPC)View official trial listing → -
Completed NCT NCT07351773
Ultrasound-Guided Stellate Ganglion Block for Alzheimer's Disease
Not yet reported Taizhou Second People's Hospital 40 participants Est. completion 2025-11-29 1 site Stand-aloneOther conditions: Alzheimer's Disease(AD), Cognitive DysfunctionView official trial listing → -
Completed NCT NCT07417670
Satisfaction With Orodispersible vs Conventional Memantine in Moderate to Severe Alzheimer's Disease
Not yet reported Carnot Laboratories 105 participants Est. completion 2025-08-18 4 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Not yet recruiting NCT NCT07470606
Memantine +/- Raloxifene for Cognitive Preservation After Radiation Therapy to the Brain
Not yet reported The University of Texas Health Science Center at San Antonio 108 participants Est. completion 2031-03 1 site Stand-aloneOther conditions: Brain TumorView official trial listing → -
Not yet recruiting NCT NCT07504198
Neuroprotection of Memantine and Rosuvastatin
Not yet reported, Not yet reported Tanta University 46 participants Est. completion 2027-05 1 siteOther conditions: Peripheral Nerve DiseaseView official trial listing → -
Not yet recruiting NCT NCT07505979
SMART Trial: Cognitive Sparing Brain Radiotherapy for Multiple Brain Metastases
Not yet reported National Taiwan University Hospital 90 participants Est. completion 2031-04Other conditions: Brain Metastases From Solid TumorsView official trial listing → -
Not yet recruiting NCT NCT07531940
Escalating Doses of Memantine in Down Syndrome (MEDS-123)
Not yet reported University Hospitals Cleveland Medical Center 25 participants Est. completion 2028-05 1 site Stand-aloneOther conditions: Down Syndrome, Intellectual Disability, Alzheimer Dementia (AD)View official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Memantine Hydrochloride, memantine
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
