About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Kybella

Company: The Maas Clinic
Mechanism: Mechanism not yet reported
Route: Route not yet reported
Recruiting trials: 21 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

21 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Oct 20, 2026

Trial details

Recruiting NCT NCT04650243

Clinical Research of Tapering UDCA in PBC Patients With a Complete Response

Not yet reported Peking Union Medical College Hospital 90 participants Est. completion 2025-05 1 site

Other conditions: Primary Biliary Cholangitis
View official trial listing →
Recruiting NCT NCT04924868

Ursodeoxycolic Acid for the Prevention of Relapsing Complications After Gallstone Acute Pancreatitis

Not yet reported Hospital General Universitario de Alicante 332 participants Est. completion 2027-07-01 18 sites

Other conditions: Acute Pancreatitis Due to Gallstones
View official trial listing →
Recruiting NCT NCT05751967

Fenofibrate Combined With Ursodeoxycholic Acid in Subjects With Primary Biliary Cholangitis

Not yet reported Xijing Hospital of Digestive Diseases 150 participants Est. completion 2027-12-01 7 sites

Other conditions: Primary Biliary Cholangitis
View official trial listing →
Recruiting NCT NCT05925309

Preventive Effect of Prophylactic Oral Antibiotics Against Cholangitis After Kasai Portoenterostomy

Not yet reported Children's Hospital of Fudan University 356 participants Est. completion 2029-12-31 1 site

Other conditions: Biliary Atresia, Cholangitis, Anti-Bacterial Agents
View official trial listing →
Recruiting NCT NCT06294847

Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment Surgery

Not yet reported Hopital Foch 120 participants Est. completion 2027-11 2 sites

Other conditions: Retinal Detachment
View official trial listing →
Recruiting NCT NCT06447402

A Trial to Compare Nebulized Amphotericin B and Nebulized Normal Saline as Maintenance in Patients With Chronic Pulmonary Aspergillosis

Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 196 participants Est. completion 2027-08-31 1 site Stand-alone

Other conditions: Chronic Pulmonary Aspergillosis, CPA, Aspergilloma
View official trial listing →
Recruiting NCT NCT06610760

Efficacy and Safety of Ursodeoxycholic Acid in Reversing Gastric Intestinal Metaplasia

Not yet reported Yongquan Shi 196 participants Est. completion 2026-10-31 6 sites

Other conditions: Gastric Intestinal Metaplasia
View official trial listing →
Recruiting NCT NCT06684106

Ursodeoxycholic Acid Attenuates Statin-Induced Impaired Glucose Tolerance

Not yet reported First Affiliated Hospital Xi'an Jiaotong University 128 participants Est. completion 2027-06-01 2 sites

Other conditions: Hyperlipidemia, Ursodeoxycholic Acid, Statin Therapy, Glucose Intolerance
View official trial listing →
Recruiting NCT NCT06755541

Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cholangitis: a Real World Study

Not yet reported Xijing Hospital of Digestive Diseases 150 participants Est. completion 2035-12 1 site

Other conditions: Primary Biliary Cholangitis (PBC)
View official trial listing →
Recruiting NCT NCT06756490

A Phase I Study of HY-2003 in the Subjects With Excessive Submental Fat Accumulation

Not yet reported Sichuan Huiyu Pharmaceutical Co., Ltd 30 participants Est. completion 2027-05-31 2 sites

Other conditions: Moderate or Severe Submental Fullness
View official trial listing →
Recruiting NCT NCT06922669

Glucocorticoids for Acute Drug Induced Liver Injury With Hyperbilirubinemia

Not yet reported General Hospital of Shenyang Military Region 232 participants Est. completion 2027-09-30 1 site

Other conditions: Drug Induced Liver Injury
View official trial listing →
Recruiting NCT NCT07014163

Evaluating the Efficacy and Safety of Embella (Deoxycholic Acid, Produced by Espad Pharmed Co.) Injection in the Management of Superficial Lipomas

Not yet reported Espad Pharmed 10 participants Est. completion 2026-06-20 2 sites

Other conditions: Lipoma
View official trial listing →
Recruiting NCT NCT07068191

Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly

Not yet reported Phenomen Pharma 90 participants Est. completion 2025-08 1 site

MASLD Other conditions: Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD), Hepatomegaly, Nonalcoholic Fatty Liver (NAFL), Fatty Liver, Fatty Liver, Alcoholic, Fatty Liver, Nonalcoholic, Fatty Liver Disease
View official trial listing →
Recruiting NCT NCT07110987

The Efficacy of Ursodeoxycholic Acid (UDCA) as Adjuvant Therapy to Phototherapy in the Management of Neonatal Indirect Hyperbilirubinemia

Not yet reported Tishreen University Hospital 70 participants Est. completion 2027-03-01 1 site

Other conditions: Hyperbilirubinemia, Neonatal Indirect
View official trial listing →
Recruiting NCT NCT07237425

Intralesional Ronkyla Plus Injection for the Treatment of Superficial Lipoma

Not yet reported Glonova Pharma Co., Ltd 56 participants Est. completion 2028-08-31 3 sites Stand-alone

Other conditions: Lipoma, Submental Fullness
View official trial listing →
Recruiting NCT NCT07296458

FIREFLY Trial: Fenofibrate Intervention---Randomized Evaluation in First-Line PBC Therapy

Not yet reported Xijing Hospital of Digestive Diseases 132 participants Est. completion 2028-12-31 1 site

Other conditions: Primary Biliary Cholangitis (PBC)
View official trial listing →
Recruiting NCT NCT07378761

Comparing UDCA and Corticosteroids in Immunotherapy Induced Cholestatic Hepatitis

Not yet reported University Hospital, Montpellier 94 participants Est. completion 2028-12 6 sites

Other conditions: Immune-Mediated Cholestasis
View official trial listing →
Recruiting NCT NCT07672860

Perioperative Ursodeoxycholic Acid for Renal Protection in Adults Undergoing Partial Nephrectomy for Renal Tumors

Not yet reported Jinling Hospital, China 162 participants Est. completion 2027-12 1 site

Other conditions: Kidney Cancer
View official trial listing →
Recruiting NCT NCT07717242

Sun Yat-Sen Treatment Strategy for Enhancing Response in Muscle-invasive Bladder Cancer

Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 80 participants Est. completion 2029-01-31 1 site

Other conditions: Bladder Urothelial Carcinoma, Bladder Cancer
View official trial listing →
Recruiting NCT NCT07725263

Low-Dose Liposomal Amphotericin B for Invasive Fungal Infection Prophylaxis in Neutropenic Children

Haikou Affiliated Hospital of Central South University Xiangya School of Medicine 30 participants Est. completion 2027-03-31 1 site

Other conditions: Thalassemia, Hematopoietic Stem Cell Transplantation, Neutropenia, Invasive Fungal Infections, Graft vs Host Disease
View official trial listing →
Recruiting NCT NCT07763054

Low-dose Liposomal Amphotericin B for Antifungal Prophylaxis in Prolonged Neutropenia Patients

Haikou Affiliated Hospital of Central South University Xiangya School of Medicine 30 participants Est. completion 2026-11-30 1 site

Other conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, Lymphoma, Multiple Myeloma, Chronic Lymphocytic Leukemia, Neutropenia, ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Invasive Fungal Infections
View official trial listing →
Completed NCT NCT00002742

Antifungal Therapy for Fever and Neutropenia in Patients Receiving Treatment for Hematologic Cancer

Not yet reported Aronex Pharmaceuticals Est. completion 2007-09 59 sites

Other conditions: Chronic Myeloproliferative Disorders, Infection, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes
View official trial listing →
Completed NCT NCT00003031

Comparison of Voriconazole and Amphotericin B in Treating Patients With Aspergillosis

Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 212 participants 74 sites

Other conditions: Infection, Pulmonary Complications
View official trial listing →
Status unknown NCT NCT00004315

Phase II Pilot Study to Compare the Bioavailability of Buffered, Enteric-Coated Ursodiol With Unmodified Ursodiol for Chronic Cholestatic Liver Disease and Cystic Fibrosis-Associated Liver Disease

Not yet reported National Center for Research Resources (NCRR) 20 participants 1 site

Other conditions: Cystic Fibrosis, Gastrointestinal Diseases, Cholestasis
View official trial listing →
Status unknown NCT NCT00004346

Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acid for Cerebrotendinous Xanthomatosis

Not yet reported National Center for Research Resources (NCRR) 5 participants 1 site

Other conditions: Cerebrotendinous Xanthomatosis
View official trial listing →
Completed NCT NCT00004441

Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis

Not yet reported Children's Hospital Medical Center, Cincinnati 39 participants Est. completion 2001-09 3 sites

Other conditions: Cystic Fibrosis
View official trial listing →
Terminated NCT NCT00004442

Study of Bile Acids in Patients With Peroxisomal Disorders

Not yet reported University of Cincinnati 25 participants Est. completion 1999-04

Other conditions: Infantile Refsum's Disease, Zellweger Syndrome, Bifunctional Enzyme Deficiency, Adrenoleukodystrophy
View official trial listing →
Completed NCT NCT00004748

Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis

Not yet reported National Center for Research Resources (NCRR) 90 participants

Other conditions: Liver Cirrhosis, Biliary
View official trial listing →
Completed NCT NCT00004784

Phase III Randomized Study of Ursodiol With Vs Without Methotrexate for Primary Biliary Cirrhosis

Not yet reported National Center for Research Resources (NCRR) 315 participants

Other conditions: Liver Cirrhosis, Biliary
View official trial listing →
Withdrawn NCT NCT00018694

Cholestanol in Humans

Not yet reported US Department of Veterans Affairs Est. completion 2009-12 1 site

Other conditions: Cerebrotendinous Xanthomatosis
View official trial listing →
Terminated NCT NCT00042549

Lithotripsy for the Treatment of Gallstones

Not yet reported Medstone International 184 participants 2 sites

Other conditions: Cholelithiasis
View official trial listing →
Terminated NCT NCT00059202

Trial of High-dose Urso in Primary Sclerosing Cholangitis

Not yet reported, Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 150 participants Est. completion 2008-06 7 sites

Other conditions: Primary Sclerosing Cholangitis
View official trial listing →
Terminated NCT NCT00062023

Comparison of Sulindac, Aspirin, and Ursodiol in Preventing Colorectal Cancer

Not yet reported M.D. Anderson Cancer Center 12 participants Est. completion 2006-05 1 site

Other conditions: Colorectal Cancer
View official trial listing →
Status unknown NCT NCT00134758

Ursodeoxycholic Acid in the Treatment of Duodenal Adenomas in Familial Adenomatous Polyposis (FAP) Patients

Not yet reported, Not yet reported Assistance Publique - Hôpitaux de Paris 90 participants Est. completion 2009-10 1 site

Other conditions: Adenomatous Polyposis Coli, Familial
View official trial listing →
Completed NCT NCT00161083

UDCA for Symptomatic Gallstone Disease

Not yet reported UMC Utrecht 180 participants Est. completion 2004-11 1 site

Other conditions: Cholecystolithiasis
View official trial listing →
Completed NCT NCT00200343

Efficacy and Safety Study of Ursodeoxycholic Acid to Treat Chronic Hepatitis C

Not yet reported Tanabe Pharma Corporation 596 participants Est. completion 2004-12 1 site

Other conditions: Chronic Hepatitis C
View official trial listing →
Status unknown NCT NCT00285597

Ursodeoxycholic Acid in Chronic Heart Failure

Not yet reported National Heart and Lung Institute Est. completion 2006-01 1 site

Heart failure
View official trial listing →
Completed NCT NCT00310505

Amphotericin B Treatment in Visceral Leishmaniasis

Not yet reported Banaras Hindu University 1500 participants 1 site

Other conditions: Visceral Leishmaniasis
View official trial listing →
Completed NCT NCT00361517

To Determine Whether Galactomannan Test Will Help to Detect Fungal Infections Early and Hence Start Treatment Early

Not yet reported Singapore General Hospital 47 participants Est. completion 2009-06-30 1 site Stand-alone

Other conditions: Aspergillosis
View official trial listing →
Completed NCT NCT00422188

Deoxycholic Acid Injection for the Treatment of Superficial Lipomas

Not yet reported Kythera Biopharmaceuticals 16 participants Est. completion 2007-11 1 site

Other conditions: Lipoma
View official trial listing →
Completed NCT NCT00465751

Effects of FXR Activation on Hepatic Lipid and Glucose Metabolism

Not yet reported University Hospital, Basel, Switzerland 30 participants 1 site

Metabolic syndrome Other conditions: Familial Hypertriglyceridemia, Familial Combined Hyperlipidemia
View official trial listing →
Status unknown NCT NCT00514774

Ursodiol in Huntington's Disease

Not yet reported Oregon Health and Science University 21 participants Est. completion 2009-06 1 site

Other conditions: Huntington Disease
View official trial listing →
Completed NCT NCT00523965

Combination Therapy in Indian Visceral Leishmaniasis

Not yet reported Banaras Hindu University 624 participants Est. completion 2010-02 1 site

Other conditions: Leishmaniasis, Visceral
View official trial listing →
Terminated NCT NCT00550862

Study of INT 747 in Combination With URSO in Patients With Primay Biliary Cirrhosis (PBC)

Not yet reported Intercept Pharmaceuticals 165 participants Est. completion 2010-12 32 sites

Other conditions: Liver Cirrhosis, Biliary
View official trial listing →
Completed NCT NCT00608842

Phase 2 Study for the Treatment of Superficial Lipomas

Not yet reported Kythera Biopharmaceuticals 62 participants Est. completion 2010-01 7 sites

Other conditions: Lipoma
View official trial listing →
Completed NCT NCT00618618

Phase 2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat

Not yet reported Kythera Biopharmaceuticals 73 participants Est. completion 2008-12 7 sites

Other conditions: Moderate or Severe Submental Fullness
View official trial listing →
Completed NCT NCT00618709

Dose-Escalation Safety and Pharmacokinetic Study of ATX-101

Not yet reported Kythera Biopharmaceuticals 24 participants Est. completion 2009-01 1 site

Other conditions: Healthy
View official trial listing →
Completed NCT NCT00618722

Phase 1-2 Study of Deoxycholic Acid Injection (ATX-101) for the Reduction of Submental Fat

Not yet reported, Not yet reported Kythera Biopharmaceuticals 85 participants Est. completion 2008-10 6 sites

Other conditions: Moderate or Severe Submental Fullness
View official trial listing →
Completed NCT NCT00628719

Single Infusion of Liposomal Amphotericin B in Indian Visceral Leishmaniasis

Not yet reported Banaras Hindu University 400 participants Est. completion 2009-03 1 site

Other conditions: Visceral Leishmaniasis
View official trial listing →
Completed NCT NCT00696969

Safety and Efficacy Study to Evaluate Different Combination Treatment Regimens for Visceral Leishmaniasis

Not yet reported Drugs for Neglected Diseases 634 participants Est. completion 2010-01 2 sites

Other conditions: Visceral Leishmaniasis
View official trial listing →
Completed NCT NCT00706381

Thyroid Hormones Homeostasis and Energy Metabolism Changes During Stimulation of Endogenously Secreted Bile Acids (BAs)

Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 31 participants Est. completion 2012-08-21 1 site

Other conditions: Healthy Volunteers
View official trial listing →
Completed NCT NCT00757081

Study to Evaluate the Effect of Injection Lypolysis (Lipodissolve) Treatments to Reduce Body Fat

Not yet reported BodyAesthetic Research Center 20 participants Est. completion 2009-12 1 site Stand-alone

Other conditions: Abdominal Subcutaneous Fat
View official trial listing →
Completed NCT NCT00808743

Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis

Not yet reported, Not yet reported Radboud University Medical Center 37 participants Est. completion 2013-01 5 sites

Other conditions: Familial Adenomatous Polyposis, Duodenal Neoplasms, Duodenal Polyps
View official trial listing →
Terminated NCT NCT00815516

Study to Compare the Efficacy and Safety of Micafungin Versus Conventional Amphotericin B for the Treatment of Neonatal Candidiasis

Not yet reported Astellas Pharma Global Development, Inc. 30 participants Est. completion 2014-12 17 sites

Other conditions: Candidiasis
View official trial listing →
Completed NCT NCT00835952

ATX-101 Abdominoplasty

Not yet reported Kythera Biopharmaceuticals 14 participants Est. completion 2009-04 2 sites

Other conditions: Characteristics of Subcutaneous Fat
View official trial listing →
Completed NCT NCT00846963

Ursodiol for Treating Parenteral Nutrition Associated Cholestasis in Neonates

Not yet reported, Not yet reported Ibrahim Mohamed 26 participants Est. completion 2013-03 1 site

Other conditions: Cholestasis
View official trial listing →
Terminated NCT NCT00851747

A Study of the Efficacy of Subcutaneous Phosphatidylcholine and Deoxycholate Injections for Localized Fat Removal

Not yet reported The Cleveland Clinic 18 participants Est. completion 2009-10 1 site Stand-alone

Other conditions: Obesity
View official trial listing →
Completed NCT NCT00858858

Clinical Studies on Bile Acids in Barrett's Esophagus

Not yet reported US Department of Veterans Affairs 60 participants Est. completion 2015-02 1 site

Other conditions: Gastroesophageal Reflux Disease
View official trial listing →
Completed NCT NCT00873275

Ursodiol, Combination Chemotherapy, and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer

Not yet reported City of Hope Medical Center 11 participants Est. completion 2025-02-26 1 site

Other conditions: Colorectal Cancer
View official trial listing →
Completed NCT NCT00877604

Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral Sclerosis

Not yet reported Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 34 participants Est. completion 2012-04 1 site

Other conditions: Amyotrophic Lateral Sclerosis
View official trial listing →
Completed NCT NCT00885703

High-Dose Fluconazole for the Treatment of Cryptococcal Meningitis in HIV-Infected Individuals

Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 168 participants Est. completion 2017-01-12 10 sites

Other conditions: Cryptococcal Meningitis, HIV Infections
View official trial listing →
Completed NCT NCT00909610

Ursodiol Tablets 500 mg Under Fasting Conditions

Not yet reported Teva Pharmaceuticals USA 80 participants Est. completion 2007-01 1 site

Other conditions: Healthy
View official trial listing →
Completed NCT NCT00909753

Ursodiol 500 mg Tablets Under Fed Conditions

Not yet reported Teva Pharmaceuticals USA 92 participants Est. completion 2006-10 1 site

Other conditions: Healthy
View official trial listing →
Completed NCT NCT00912301

Cheno Effect on Transit in Health and IBS-C

Not yet reported Mayo Clinic 36 participants Est. completion 2009-12 1 site

Other conditions: Constipation-predominant Irritable Bowel Syndrome
View official trial listing →
Completed NCT NCT01032187

Amphotericin B to Treat Visceral Leishmaniasis in Brazilian Children

Not yet reported University of Brasilia 101 participants Est. completion 2010-07 2 sites Stand-alone

Other conditions: Visceral Leishmaniasis
View official trial listing →
Completed NCT NCT01032889

Deoxycholic Acid Injection Submental Fat (SMF) Magnetic Resonance Imaging (MRI) and Subject-reported Outcome Measures Study

Not yet reported Kythera Biopharmaceuticals 129 participants Est. completion 2010-12 10 sites

Other conditions: Moderate or Severe Submental Fullness
View official trial listing →
Completed NCT NCT01073202

Effects of Ursodeoxycholic Acid on Graft Recovery Early After Adult Liver Transplantation

Not yet reported Shanghai Jiao Tong University School of Medicine 112 participants Est. completion 2009-01 1 site

Other conditions: Liver Transplantation, Ischemia-reperfusion Injury, Cholestasis
View official trial listing →
Completed NCT NCT01088607

Safety and Efficacy Study of Ursodeoxycholic Acid Therapy in Pediatric Primary Sclerosing Cholangitis

Not yet reported University of Tennessee 27 participants Est. completion 2017-06 12 sites

Other conditions: Primary Sclerosing Cholangitis
View official trial listing →
Completed NCT NCT01097304

Ursodiol in Treating Patients With Barrett Esophagus and Low-Grade Dysplasia

Not yet reported National Cancer Institute (NCI) 36 participants Est. completion 2014-07 4 sites

Other conditions: Barrett Esophagus, Esophageal Carcinoma
View official trial listing →
Status unknown NCT NCT01141322

Cholestatic Drug-induced Liver Injury

Not yet reported Taipei Veterans General Hospital, Taiwan 180 participants Est. completion 2010-07 1 site

Other conditions: Hepatitis, Toxic
View official trial listing →
Completed NCT NCT01149304

Preventive Effect of Enoxaparin, Pentoxifylline and Ursodeoxycholic Acid to Radiation Induced Liver Toxicity

Not yet reported University of Magdeburg 22 participants 1 site

Other conditions: Colorectal Cancer, Liver Metastases, Irradiation Damage, Radiation Induced Liver Disease
View official trial listing →
Withdrawn NCT NCT01226823

Ursodeoxycholic Acid And Cholestasis Of Pregnancy

Not yet reported University of Bologna Est. completion 2013-11 7 sites

Other conditions: Intrahepatic Cholestasis of Pregnancy
View official trial listing →
Completed NCT NCT01294644

Evaluation of Safety and Efficacy of Deoxycholic Acid Injection (ATX-101) in the Reduction of Submental Fat

Not yet reported Kythera Biopharmaceuticals 360 participants Est. completion 2012-02 29 sites

Other conditions: Moderate or Severe Submental Fullness
View official trial listing →
Completed NCT NCT01305577

Evaluation of Safety and Efficacy of Deoxycholic Acid Injection (ATX-101) in the Reduction of Submental Fat

Not yet reported Kythera Biopharmaceuticals 363 participants Est. completion 2012-01 30 sites

Other conditions: Moderate or Severe Submental Fullness
View official trial listing →
Terminated NCT NCT01310738

Efficacy and Safety Study of Drugs for Treatment of Visceral Leishmaniasis in Brazil

Not yet reported University of Brasilia 378 participants Est. completion 2015-02 5 sites Stand-alone

Other conditions: Visceral Leishmaniasis
View official trial listing →
Completed NCT NCT01319916

Lipid and Adipokine Profiles Following Subcutaneous Injection of ATX-101 Into Abdominal Fat Tissue

Not yet reported Kythera Biopharmaceuticals 10 participants Est. completion 2011-01 1 site

Other conditions: Healthy
View official trial listing →
Completed NCT NCT01320761

A Study to Assess Injection Comfort of Two Formulations of ATX-101

Not yet reported Kythera Biopharmaceuticals 24 participants 2 sites

Other conditions: Healthy
View official trial listing →
Status unknown NCT NCT01337440

Efficacy and Safety of Ursodeoxycholic Acid (UDCA) Added to the DPP-4 Inhibitor in People With Type 2 Diabetes and Chronic Liver Diseases

Not yet reported Kanazawa University 20 participants Est. completion 2013-03 1 site

Type 2 diabetes Other conditions: Chronic Liver Disease
View official trial listing →
Completed NCT NCT01426373

Open-Label Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area

Not yet reported Kythera Biopharmaceuticals 165 participants Est. completion 2013-06 18 sites

Other conditions: Moderate or Severe Submental Fullness
View official trial listing →
Status unknown NCT NCT01440309

Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Refractory Primary Biliary Cirrhosis

Not yet reported Robert Chunhua Zhao, MD, PhD 20 participants Est. completion 2013-12 1 site

Other conditions: Primary Biliary Cirrhosis
View official trial listing →
Completed NCT NCT01462786

To Evaluate the Safety, Tolerability and to Compare the Pharmacokinetic Profile of ATX-101

Not yet reported Kythera Biopharmaceuticals 5 participants Est. completion 2011-12 1 site

Other conditions: Healthy
View official trial listing →
Status unknown NCT NCT01483248

Human Menstrual Blood-derived Mesenchymal Stem Cells for Patients With Liver Cirrhosis

Not yet reported, Not yet reported S-Evans Biosciences Co., Ltd. 50 participants Est. completion 2015-10 1 site

Other conditions: Liver Cirrhosis, Fibrosis, Liver Disease, Digestive System Disease
View official trial listing →
Completed NCT NCT01505569

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Not yet reported Masonic Cancer Center, University of Minnesota 44 participants Est. completion 2024-02-01 1 site

Obstructive sleep apnea Other conditions: Ewing's Family Tumors, Renal Tumors, Hepatoblastoma, Soft Tissue Sarcoma, Primary Malignant Brain Neoplasms, Retinoblastoma, Medulloblastoma, Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET), Atypical Teratoid/Rhabdoid Tumor (AT/RT), CNS Tumors, Germ Cell Tumors
View official trial listing →
Completed NCT NCT01510860

Ursofalk Tablets (500 mg) Versus Ursofalk Capsules (250 mg) in the Treatment of Primary Biliary Cirrhosis

Not yet reported Dr. Falk Pharma GmbH 65 participants Est. completion 2010-07 1 site

Other conditions: Primary Biliary Cirrhosis
View official trial listing →
Completed NCT NCT01542034

Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area

Not yet reported Kythera Biopharmaceuticals 506 participants Est. completion 2013-08 36 sites

Other conditions: Moderate or Severe Submental Fullness
View official trial listing →
Completed NCT NCT01546142

Phase 3 Study of Deoxycholic Acid Injection (ATX-101) Versus Placebo for the Reduction of Localized Subcutaneous Fat in the Submental Area

Not yet reported Kythera Biopharmaceuticals 516 participants Est. completion 2013-08 35 sites

Other conditions: Moderate or Severe Submental Fullness
View official trial listing →
Completed NCT NCT01548079

Ursodeoxycholic Acid in Bariatric Surgery

Not yet reported Sahlgrenska University Hospital 40 participants Est. completion 2010-05

Other conditions: Non-alcoholic Fatty Liver Disease, Morbid Obesity
View official trial listing →
Completed NCT NCT01576458

Ursodeoxycholic Acid in the Treatment of Intrahepatic Cholestasis of Pregnancy

Not yet reported Turku University Hospital 20 participants Est. completion 1998-12 1 site

Other conditions: Intrahepatic Cholestasis, Pregnancy
View official trial listing →
Completed NCT NCT01632917

Open-Label Pharmacokinetic Study of Final Formulations of ATX-101

Not yet reported Kythera Biopharmaceuticals 24 participants Est. completion 2012-07 1 site

Other conditions: Healthy
View official trial listing →
Completed NCT NCT01666223

Effect of Bile Acids on GLP-1 Secretion

Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2013-06 1 site

Type 2 diabetes Other conditions: Obesity
View official trial listing →
Completed NCT NCT01674946

Effect of Bile Acids on the Secretion of Satiation Peptides in Humans

Not yet reported University Hospital, Basel, Switzerland 12 participants Est. completion 2012-05 1 site

Other conditions: Echolocation
View official trial listing →
Status unknown NCT NCT01688375

The Effect of Ursodeoxycholic Acid in Liver Functional Restoration of Patients With Obstructive Jaundice

Not yet reported University Clinical Centre of Kosova 54 participants Est. completion 2013-12 3 sites

Other conditions: Obstructive Jaundice
View official trial listing →
Completed NCT NCT01829698

Efficacy and Safety Study of TUDCA Compare UDCA to Treatment Chronic Cholestatic Liver Disease-PBC

Not yet reported Beijing Trendful Kangjian Medical Information Consulting Limited Company 199 participants Est. completion 2014-02 1 site

Other conditions: Cholestatic Liver Disease
View official trial listing →
Completed NCT NCT01857284

Safety and Efficacy of Tauroursodeoxycholic Acid Versus Ursofalk in the Treatment of Adult Primary Biliary Cirrhosis

Not yet reported Beijing Friendship Hospital 216 participants Est. completion 2013-01 25 sites

Other conditions: Primary Biliary Cirrhosis
View official trial listing →
Completed NCT NCT01857479

A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis

Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 21 participants Est. completion 2015-06 1 site Stand-alone

Other conditions: Allergic Bronchopulmonary Aspergillosis
View official trial listing →
Completed NCT NCT01899703

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Repeat Doses of GSK2330672 Administration in Subjects With Primary Biliary Cirrhosis (PBC) and Symptoms of Pruritus

Not yet reported GlaxoSmithKline 22 participants Est. completion 2015-10-07 3 sites

Other conditions: Cholestasis, Intrahepatic
View official trial listing →
Completed NCT NCT01904058

Phase 2 Study to Evaluate LUM001 in Combination With Ursodeoxycholic Acid in Patients With Primary Biliary Cirrhosis

Not yet reported Mirum Pharmaceuticals, Inc. 66 participants Est. completion 2015-04 24 sites

Other conditions: PBC, Primary Biliary Cirrhosis
View official trial listing →
Terminated NCT NCT01945281

Safety, Tolerability, and Efficacy of Caspofungin Versus Amphotericin B Deoxycholate in the Treatment of Invasive Candidiasis in Neonates and Infants (MK-0991-064)

Not yet reported Merck Sharp & Dohme LLC 51 participants Est. completion 2018-02-28

Other conditions: Candidiasis, Invasive
View official trial listing →
Completed NCT NCT01974336

The Preventative and Therapeutical Effect of Ursodeoxycholic Acid(UDCA) to Short Bowel Syndrome Patients

Not yet reported Jinling Hospital, China 30 participants Est. completion 2016-09 1 site

Other conditions: Short Bowel Syndrome
View official trial listing →
Completed NCT NCT02007434

Patient Experience Study of Deoxycholic Acid Injection

Not yet reported Kythera Biopharmaceuticals 84 participants Est. completion 2014-06 1 site

Other conditions: Moderate or Severe Submental Fullness
View official trial listing →
Completed NCT NCT02016365

Safety and Efficacy Study of Doxycycline/UrsoDeoxyCholicAcid on Disease Progression in ATTR Amyloidosis

Not yet reported Umeå University 55 participants Est. completion 2014-12 3 sites

Other conditions: Transthyretin Amyloidosis, Cardiomyopathy
View official trial listing →
Completed NCT NCT02021110

Ursodeoxycholic Acid as Treatment for Polycystic Liver Disease

Not yet reported Radboud University Medical Center 34 participants Est. completion 2015-10 3 sites

Other conditions: Polycystic Liver Disease, Polycystic Kidney, Autosomal Dominant
View official trial listing →
Completed NCT NCT02033876

Ursodiol on Insulin Sensitivity, Gastric Emptying and Body Weight With Type 2 Diabetes on Metformin

Not yet reported Mayo Clinic 24 participants Est. completion 2017-03 1 site

Type 2 diabetes
View official trial listing →
Completed NCT NCT02035267

Safety Study of ATX-101 (Deoxycholic Acid) in Subjects With Mild or Extreme Fullness of Submental Fat

Not yet reported Kythera Biopharmaceuticals 93 participants Est. completion 2015-06 8 sites

Other conditions: Moderate to Severe Convexity of Submental Fat, Safety, Efficacy
View official trial listing →
Completed NCT NCT02123134

Safety Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area in Subjects 65 to 75 Years of Age

Not yet reported Kythera Biopharmaceuticals 55 participants Est. completion 2015-09 6 sites

Other conditions: Moderate to Severe Convexity of Submental Fat, Safety, Efficacy
View official trial listing →
Status unknown NCT NCT02136030

Liposomal Amphotericin B for the Treatment of Cryptococcal Meningitis

Not yet reported TTY Biopharm 84 participants Est. completion 2016-12 1 site

Other conditions: Cryptococcal Meningitis
View official trial listing →
Completed NCT NCT02159729

Long Term Follow-up Study on Safety and Maintenance of Efficacy of ATX-101

Not yet reported Kythera Biopharmaceuticals 205 participants Est. completion 2015-12 20 sites

Other conditions: Submental Fat, Healthy
View official trial listing →
Completed NCT NCT02163902

Long-term Follow-up Study on Safety and Maintenance of Efficacy of ATX-101

Not yet reported Kythera Biopharmaceuticals 224 participants Est. completion 2016-08 15 sites

Other conditions: Submental Fat, Healthy
View official trial listing →
Terminated NCT NCT02244944

Ezetimibe-Ursodiol Combination Therapy on Biomarkers of Liver Function and Sterol Balance in Subjects With NAFLD

Not yet reported Gregory Graf, PhD 2 participants Est. completion 2015-09 1 site

MASLD
View official trial listing →
Terminated NCT NCT02283905

Amphotericin-B and Voriconazole for Pulmonary Blastomycosis

Not yet reported University of Manitoba 2 participants Est. completion 2020-09-25 1 site

Other conditions: Blastomycosis
View official trial listing →
Completed NCT NCT02314208

Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5

Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 12 participants Est. completion 2018-01-01 1 site

Other conditions: Spastic Paraplegia, Hereditary
View official trial listing →
Status unknown NCT NCT02319629

Preventive Therapy With Ursodiol to Reduce the Incidence of Gallstones Formation in Patients After Bariatric Surgery

Not yet reported HaEmek Medical Center, Israel 266 participants Est. completion 2018-12 1 site

Other conditions: Morbid Obesity
View official trial listing →
Status unknown NCT NCT02338635

Effect of Ursodeoxycholic Acid on Peritoneal Function in Patients on Peritoneal Dialysis

Not yet reported Ewha Womans University 55 participants Est. completion 2018-01

Other conditions: End-Stage Kidney Disease
View official trial listing →
Completed NCT NCT02340247

Effects of Bile Acids on GLP-1 Secretion After Roux-en-Y Gastric Bypass

Not yet reported Hvidovre University Hospital 11 participants 1 site

Other conditions: Severe Obesity
View official trial listing →
Completed NCT NCT02385032

Comparative Bioavailability Study of UDCA

Not yet reported Daewoong Pharmaceutical Co. LTD. 50 participants Est. completion 2015-05

Other conditions: Healthy
View official trial listing →
Completed NCT NCT02415777

Clinical Trial to Evaluate the Efficacy and Safety of 'URSA SOFT CAP. (UDCA-003)' in Fatigue Patients With Liver Dysfunction

Not yet reported Daewoong Pharmaceutical Co. LTD. 168 participants Est. completion 2015-07 1 site

Other conditions: Fatigue
View official trial listing →
Completed NCT NCT02418130

A Multi-center, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of 'Ursa Complex Soft Cap. (UDCA-004)' in Patients With Physical Fatigue.

Not yet reported Daewoong Pharmaceutical Co. LTD. 166 participants Est. completion 2015-03 1 site

Other conditions: Fatigue
View official trial listing →
Withdrawn NCT NCT02420496

Enteral Fish Oil is Superior to Ursodeoxycholic Acid (UDCA) and Placebo for the Treatment of Cholestasis in Infants

Not yet reported The University of Texas Health Science Center at San Antonio Est. completion 2016-06 1 site

Other conditions: Cholestasis, Liver Disease
View official trial listing →
Completed NCT NCT02438813

Condition of Submental Fullness and Treatment Outcomes Registry

Kythera Biopharmaceuticals 1029 participants Est. completion 2016-11-10 95 sites

Other conditions: Submental Fullness
View official trial listing →
Terminated NCT NCT02472509

The Role of Ursodeoxycholic Acid in Treatment of Gallstones in Hemolytic Disorders

Not yet reported Shaare Zedek Medical Center 3 participants Est. completion 2017-09-10 1 site

Other conditions: Hemolytic Disorders, Gallstones
View official trial listing →
Completed NCT NCT02622685

A Multiple Dose Study of DWP10292 and UDCA in Healthy Male Subjects

Not yet reported Daewoong Pharmaceutical Co. LTD. 58 participants Est. completion 2016-02

Other conditions: Healthy
View official trial listing →
Status unknown NCT NCT02721862

Effectiveness of Ursodeoxycholic Acid Use in the Prevention of Gallstone Formation After Sleeve Gastrectomy

Not yet reported American University of Beirut Medical Center 100 participants Est. completion 2019-03 2 sites

Other conditions: Cholelithiasis
View official trial listing →
Completed NCT NCT02748616

C. Difficile and Ursodiol

Not yet reported NYU Langone Health 9 participants Est. completion 2020-01-31 1 site

Other conditions: Diarrhea
View official trial listing →
Status unknown NCT NCT02789644

Clinical Trial to Investigate Pharmacokinetics, Metabolomics and Biomarker in Elderly After UDCA Administration

Not yet reported Seoul National University Hospital 16 participants Est. completion 2016-07 1 site

Other conditions: Aged
View official trial listing →
Completed NCT NCT02841306

Ursodeoxycholic Acid for Rhegmatogenous Retinal Detachment

Not yet reported Francine Behar-Cohen 26 participants Est. completion 2017-09 1 site

Other conditions: Rhegmatogenous Retinal Detachment
View official trial listing →
Completed NCT NCT02876484

Effects of Bile Acids and Bile Acid Sequestrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass

Not yet reported Hvidovre University Hospital 12 participants Est. completion 2020-11 1 site

Other conditions: Severe Obesity
View official trial listing →
Status unknown NCT NCT02936596

Remission Induction of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome

Not yet reported Xiaoli Fan 53 participants Est. completion 2022-06-01 1 site

Other conditions: Hepatitis, Autoimmune, Cholangitis, Liver Cirrhosis, Biliary, Cholestasis
View official trial listing →
Status unknown NCT NCT02937012

Use of Bezafibrate in Patients With Primary Biliary Cirrhosis to Archive Complete Biochemical Response in Non-responders

Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 34 participants Est. completion 2019-12 1 site

Other conditions: Primary Biliary Cirrhosis
View official trial listing →
Status unknown NCT NCT02943707

Autologous Bone Marrow Stem Cells Infusion for the Treatment of Liver Diseases.

Not yet reported Wenzhou Medical University 40 participants Est. completion 2020-10 1 site

Other conditions: Liver Diseases
View official trial listing →
Completed NCT NCT02952963

Effect of Bile Acids and Bile Acid Sequstrants on GLP-1 Secretion After Roux-en-Y Gastric Bypass

Not yet reported Hvidovre University Hospital 8 participants Est. completion 2020-11 1 site

Other conditions: Severe Obesity
View official trial listing →
Withdrawn NCT NCT02965911

Efficacy and Safety of Fenofibrate Combined With UDCA in PBC Patients With an Incomplete Biochemical Response to UDCA

Not yet reported, Not yet reported Beijing 302 Hospital Est. completion 2021-09-08 1 site

Other conditions: Primary Biliary Cirrhosis
View official trial listing →
Completed NCT NCT02967250

Brain Bioenergetics in Parkinson's Disease and Response to Repeated Oral UDCA Treatment

Not yet reported University of Minnesota 5 participants Est. completion 2022-02-28 1 site

Other conditions: Parkinson Disease
View official trial listing →
Completed NCT NCT02979210

Infant Fecal Insult Study

Not yet reported Kimberly-Clark Corporation 24 participants Est. completion 2017-02-01 1 site

Other conditions: Dermatitis
View official trial listing →
Status unknown NCT NCT03000218

Evaluation of PK and Biomarkers After UDCA Administrations to Subjects Who Are Overweight and Have Liver Problems

Not yet reported Seoul National University Hospital 30 participants 1 site

Other conditions: Overweight, Abnormal Liver Function Tests
View official trial listing →
Status unknown NCT NCT03004118

Therapeutic Effect of Ursodeoxycholic Acid in Functional Dyspepsia

Not yet reported Universitaire Ziekenhuizen KU Leuven 16 participants Est. completion 2025-11

Other conditions: Functional Dyspepsia
View official trial listing →
Status unknown NCT NCT03056274

Metformin in Intrahepatic Cholestasis of Pregnancy

Not yet reported, Not yet reported Epsom and St Helier University Hospitals NHS Trust 40 participants Est. completion 2019-09

Other conditions: Intrahepatic Cholestases, Pregnancy Complications
View official trial listing →
Completed NCT NCT03168555

Changes in Bile Acid Homeostasis and Stool Habits After Cholecystectomy

Not yet reported Zealand University Hospital 23 participants Est. completion 2019-05-15 1 site

Other conditions: Bile Acid Malabsorption, Cholelithiasis
View official trial listing →
Completed NCT NCT03188146

Performance of Scoring Systems in Chinese Patients With Primary Biliary Cholangitis (PBC) on Ursodeoxycholic Acid

Humanity and Health Research Centre 57 participants Est. completion 2025-02-15 1 site

Other conditions: Primary Biliary Cholangitis (PBC)
View official trial listing →
Terminated NCT NCT03201952

Examination of the Metabolic Effects of Direct Bile Salt Delivery to the Ileum in Humans

Not yet reported Vanderbilt University Medical Center 2 participants Est. completion 2020-05-01 1 site

Other conditions: Glucose Intolerance, Gastric Bypass Surgery
View official trial listing →
Completed NCT NCT03241563

Subcutaneous Sodium Deoxycholate Injections With or Without Triamcinolone for Reduction of Submental Fat

Not yet reported Goldman, Butterwick, Fitzpatrick and Groff 20 participants Est. completion 2017-02 1 site

Other conditions: Fat Reduction
View official trial listing →
Terminated NCT NCT03284034

Cryolipolysis Versus ATX-101 (Deoxycholic Acid) for Upper Back Fat

Not yet reported Northwestern University 8 participants Est. completion 2020-06-08 1 site

Other conditions: Upper Back Fat
View official trial listing →
Completed NCT NCT03361176

Kybella With Triamcinolone

Not yet reported Goldman, Butterwick, Fitzpatrick and Groff 30 participants Est. completion 2018-12-18 2 sites Stand-alone

Other conditions: Adiposity
View official trial listing →
Completed NCT NCT03489889

Development of Ursodeoxycholic Acid 300 mg at Hospital Das Clinicas of the University of São Paulo School of Medicine

Not yet reported University of Sao Paulo General Hospital 30 participants Est. completion 2018-06 1 site

Other conditions: Ursodeoxycholic Acid, Primary Biliary Cirrhosis
View official trial listing →
Completed NCT NCT03510598

Submental Study (Sequential Treatment Approach)

Not yet reported Zeltiq Aesthetics 16 participants Est. completion 2018-12-08 1 site Stand-alone

Other conditions: Body Fat Disorder
View official trial listing →
Completed NCT NCT03512808

A Single-dose, Comparative Bioavailability Study of Two Formulations of Ursodiol 500mg Tablets Under Fasting Conditions

Not yet reported Daewoong Pharmaceutical Co. LTD. 77 participants Est. completion 2017-07-31 1 site

Other conditions: Healthy
View official trial listing →
Completed NCT NCT03512821

A Single-dose, Comparative Bioavailability Study of Two Formulations of Ursodiol 500mg Tablets Under Fed Conditions

Not yet reported Daewoong Pharmaceutical Co. LTD. 77 participants Est. completion 2017-11-30 1 site

Other conditions: Healthy
View official trial listing →
Status unknown NCT NCT03578055

BDD With UDCA Therapy After Laparoscopic Cholecystectomy

Not yet reported Ewha Womans University Mokdong Hospital 172 participants Est. completion 2019-12-31 1 site

Other conditions: Cholecystitis, Acute, Cholecystitis, Chronic
View official trial listing →
Completed NCT NCT03586674

Fibrates in Pediatric Cholestasis

Not yet reported Hoda A. Atta 50 participants Est. completion 2018-06-20 2 sites

Other conditions: Chronic Cholestasis
View official trial listing →
Terminated NCT NCT03602976

Ursodeoxycholic Acid (UDCA) for Hepatic Sarcoidosis

Not yet reported Ethan Weinberg 7 participants Est. completion 2022-01-12 1 site

Other conditions: Hepatic Sarcoidosis, Elevated Alkaline Phosphatase
View official trial listing →
Completed NCT NCT03659058

Impact of Ursodeoxycholic Acid, Silymarin, Antioxidants and Colchicine on Fibrosis Regression in HCV After SVR

Not yet reported Zagazig University 400 participants Est. completion 2018-08-01

Other conditions: Fibrosis, Liver
View official trial listing →
Completed NCT NCT03664596

Therapeutic And Dietary Effects Of The Sublimated Mare's Milk Supplement In Patients With Non-Alcoholic Steatohepatitis

Not yet reported Medical Centre Hospital of the President's Affairs Administration, Republic of Kazakhstan 80 participants Est. completion 2020-12-01 1 site

Other conditions: Non-alcoholic Steatohepatitis
View official trial listing →
Completed NCT NCT03665519

Clinical Trial on the Effect of the Sublimated Mare Milk Supplement on Primary Biliary Cholangitis

Not yet reported National Scientific Medical Center, Kazakhstan 40 participants Est. completion 2020-12-01 1 site

Other conditions: Primary Biliary Cirrhosis
View official trial listing →
Withdrawn NCT NCT03678480

A Study of HTD1801 in Adolescents With Primary Sclerosing Cholangitis (PSC)

Not yet reported HighTide Therapeutics (Hong Kong) Limited Est. completion 2021-11-04

Other conditions: Primary Sclerosing Cholangitis, Cholangitis, Cholangitis, Sclerosing, Bile Duct Diseases, Biliary Tract Diseases, Digestive System Diseases, Adolescent
View official trial listing →
Completed NCT NCT03682471

Long-term 24-month Follow-up Study on Safety and Maintenance of Efficacy of ATX-101 (Sodium Deoxycholate Injection)

Allergan 201 participants Est. completion 2013-12-13 18 sites

Other conditions: Subcutaneous Fat
View official trial listing →
Terminated NCT NCT03691415

Evaluation of the Safety and Effectiveness of BELKYRA® Inj. for the Treatment of Patients With Submental Fullness Due to Submental Fat: A Postmarketing Surveillance Study in Korea

Allergan 71 participants Est. completion 2020-04-14 4 sites

Other conditions: Submental Fullness
View official trial listing →
Terminated NCT NCT03724175

The Role of Secondary Bile Acids in Intestinal Inflammation

Not yet reported, Not yet reported Stanford University 2 participants Est. completion 2026-03-02 1 site

Other conditions: Ulcerative Colitis, Pouchitis
View official trial listing →
Completed NCT NCT03844100

Effectiveness and Safety in Administrating CNU® Capsule to Refractory Functional Dyspepsia Patients

Not yet reported, Not yet reported Gangnam Severance Hospital 37 participants Est. completion 2021-08-04 6 sites

Other conditions: Dyspepsia, Biliary Dysplasia
View official trial listing →
Completed NCT NCT04054011

Safety and Efficacy of Deoxycholic Acid Injection for Reduction of Upper Inner Thigh Fat

Not yet reported University of California, San Diego 15 participants Est. completion 2020-05-19 1 site Stand-alone

Other conditions: Adiposity
View official trial listing →
Status unknown NCT NCT04072640

Three Induction Treatments on Cryptococcal Meningitis

Not yet reported First Affiliated Hospital of Zhejiang University 120 participants Est. completion 2022-12-01 1 site Stand-alone

Other conditions: Cryptococcal Meningitis, HIV/AIDS
View official trial listing →
Status unknown NCT NCT04076527

Prospective, Multicenter Cohort Study on Primary Biliary Cholangitis

University of Leipzig 1200 participants Est. completion 2024-03 50 sites

Other conditions: PBC, Primary Biliary Cholangitis
View official trial listing →
Completed NCT NCT04089722

Efficacy and Safety of Deoxycholic Acid Injections for Removal of Adipose Tissue in the "Bra Strap Fat" Region

Not yet reported Juva Skin & Laser Center 22 participants Est. completion 2020-10-22 1 site

Other conditions: Brassiere Strap Fat (BSF), Bra Strap Fat (BSF)
View official trial listing →
Status unknown NCT NCT04281082

Genetic Polymorphisms of ABCB11 and ABCB4 in Women With Intrahepatic Cholestasis of Pregnancy (ICP) and in Their First Degree Relatives

Alexandra Hospital, Athens, Greece 50 participants Est. completion 2022-01-31 1 site

Other conditions: Cholestasis of Pregnancy
View official trial listing →
Active, not recruiting NCT NCT04407650

Ursodeoxycholic Acid vs Metformin in Gestational Diabetes Mellitus

Not yet reported King's College London 64 participants Est. completion 2025-05-31 1 site

Other conditions: Gestational Diabetes
View official trial listing →
Completed NCT NCT04502381

Combined Inhalational With Intravenous Amphotericin B Versus Intravenous Amphotericin B Alone for Pulmonary Mucormycosis

Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2021-12-30 1 site Stand-alone

Other conditions: Pulmonary Mucormycosis
View official trial listing →
Withdrawn NCT NCT04531878

BSEP Function Rescue During Childhood Inhereditary Cholestatic Diseases

Not yet reported, Not yet reported Children's Hospital of Fudan University Est. completion 2023-02-08

Other conditions: Hereditary Diseases, Cholestasis, Intrahepatic
View official trial listing →
Status unknown NCT NCT04542473

Pancreatic Enzymes and Bile Acids in Acutely Ill Severely Malnourished Children

Not yet reported, Not yet reported University of Oxford 400 participants Est. completion 2024-06-30 4 sites

Other conditions: SEPSIS, MALNUTRITION, CHILD
View official trial listing →
Status unknown NCT NCT04617561

Ursodeoxycholic Acid Combined With Low Dose Glucocorticoid in the Treatment of PBC With AIH Features II

Not yet reported West China Hospital 90 participants Est. completion 2022-11-01 1 site

Other conditions: Hepatitis, Autoimmune, Primary Biliary Cholangitis
View official trial listing →
Completed NCT NCT04640571

Impact of Metformin and Polysorbate 80 on Drug Absorption and Disposition

Not yet reported University of Maryland, Baltimore 18 participants Est. completion 2021-11-01 1 site

Other conditions: Bile Salt Export Pump (BSEP) Transporter, Polysorbate 80
View official trial listing →
Completed NCT NCT04730583

Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

Not yet reported Massachusetts General Hospital 34 participants Est. completion 2024-04-19 1 site

Other conditions: Cutaneous Neurofibroma
View official trial listing →
Status unknown NCT NCT04751188

A Study to Assess Efficacy and Safety of Bezafibrate in Patients With Primary Biliary Cholangitis

Not yet reported Instituto Mexicano del Seguro Social 11 participants Est. completion 2021-07 1 site

Other conditions: Primary Biliary Cirrhosis
View official trial listing →
Status unknown NCT NCT04786795

MITE in the Treatment of Dyspepsia After Cholecystectomy

Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 990 participants Est. completion 2022-02

Other conditions: Patients With Dyspeptic Symptoms After Cholecystectomy
View official trial listing →
Status unknown NCT NCT04810156

Treatment Efficacy of Corticosteroids and Mycophenolate Mofetil in Patients With Immune Related Hepatitis

Not yet reported Inge Marie Svane 60 participants Est. completion 2025-11-07 5 sites

Other conditions: Hepatitis, Drug-Induced
View official trial listing →
Completed NCT NCT04834557

Evaluating the Effect of Digoxin and Ursodeoxycholic Acid in Patients With Rheumatoid Arthritis

Not yet reported Tanta University 90 participants Est. completion 2022-09-30 1 site

Other conditions: Rheumatoid Arthritis
View official trial listing →
Completed NCT NCT04841551

Kybella for the Treatment of Flank Fat (FF)

Not yet reported Beer, Kenneth R., M.D., PA 10 participants Est. completion 2022-03-02 1 site

Other conditions: Adiposity
View official trial listing →
Completed NCT NCT04910178

Follow-up of NAFLD Patients With MRI-PDFF

Not yet reported Asmaa Abdelfattah Elsayed 80 participants Est. completion 2021-12-30 1 site

MASLD Other conditions: Diabetes Type 2
View official trial listing →
Completed NCT NCT04977661

Comparing the Effects of Vitamin E, Ursodeoxycholic Acid and Pentoxyfylline on Egyptian Non-alcoholic Steatohepatitis (NASH) Patients

Not yet reported Kafrelsheikh University 102 participants Est. completion 2021-01-10 1 site

MASH
View official trial listing →
Status unknown NCT NCT05043194

Ursodeoxycholic Acid Prevents Total Parenteral Nutrition Cholestasis

Not yet reported Wei Liu 80 participants Est. completion 2022-07-30 1 site

Other conditions: Cholestasis of Parenteral Nutrition
View official trial listing →
Status unknown NCT NCT05416580

Efficacy of Ursodeoxycholic Acid (UDCA) in Patients With Type 2 Diabetes

Not yet reported University of Banja Luka 60 participants Est. completion 2024-04 1 site

Type 2 diabetes
View official trial listing →
Status unknown NCT NCT05467553

A Study to Compare P1101 Plus TAF With or Without UDCA in Patients With HBV and HDV Co-Infection

Not yet reported National Taiwan University Hospital 30 participants Est. completion 2025-08-31 2 sites

Other conditions: Hepatitis D
View official trial listing →
Completed NCT NCT05499026

Safety and Efficacy of CDCA in CTX Chenodeoxycholic Acid (CDCA) in Patients Affected by Cerebrotendinous Xanthomatosis (CTX)

Leadiant Biosciences Ltd. 28 participants Est. completion 2015-06-03

Other conditions: Cerebrotendinous Xanthomatoses
View official trial listing →
Status unknown NCT NCT05500937

Effect of UDCA on the New Onset Diabetes and Glucose Intolerance Induced by Statin

Not yet reported, Not yet reported First Affiliated Hospital Xi'an Jiaotong University 1000 participants Est. completion 2024-12-31 1 site

Other conditions: Diabetes Mellitus
View official trial listing →
Terminated NCT NCT05526807

Ursodeoxycholic Acid in C. Difficile Infection

Not yet reported Nottingham University Hospitals NHS Trust 6 participants Est. completion 2023-12-31 1 site

Other conditions: Clostridioides Difficile Infection
View official trial listing →
Completed NCT NCT05642624

The PK/PD of Deoxycholic Acid Amphotericin B in Invasive Fungal Infection Patients With Sepsis/Septic Shock

Southeast University, China 20 participants Est. completion 2022-06-28 2 sites

Other conditions: Fungal Infection
View official trial listing →
Completed NCT NCT05659654

The Application of Ursodeoxycholic Acid for the Prevention of SARS-CoV-2 Infection (COVID-19)

Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 95 participants Est. completion 2023-03-08 1 site

Other conditions: COVID-19
View official trial listing →
Completed NCT NCT05690646

Prophylactic Effect of Nirmatrelvir/Ritonavir and Ursodeoxycholic Acid on Reducing Complications After Cardiac Surgery

Not yet reported China National Center for Cardiovascular Diseases 491 participants Est. completion 2024-08-01 1 site

Other conditions: Cardiac Surgery
View official trial listing →
Status unknown NCT NCT05753852

Open Label Extension of TUDCA-ALS Study

Not yet reported Humanitas Mirasole SpA 184 participants Est. completion 2025-03-31 23 sites

Other conditions: Amyotrophic Lateral Sclerosis
View official trial listing →
Status unknown NCT NCT05812612

UDCA in the Treatment of COVID-19 Infection and Its Clinical Prognosis in Patients With Autoimmune Liver Disease

Beijing Ditan Hospital 2000 participants Est. completion 2023-12-30 1 site

Other conditions: COVID-19 Infection
View official trial listing →
Completed NCT NCT05832697

An Exploratory Clinical Trial to Evaluate and Compare Safety and Pharmacokinetic Characteristics After Administration of the DWJ1439, DWJ1464, DWC202108 or DWC202109 in Healthy Adult Volunteers

Not yet reported Daewoong Pharmaceutical Co. LTD. 44 participants Est. completion 2023-01-30 1 site

Other conditions: Healthy Subject
View official trial listing →
Status unknown NCT NCT05849558

Study to Compare the Efficacy & Safety of Ursoplus Capsules vs. UDCA vs. Placebo Among Chronic Liver Disease Patients

Not yet reported MinaPharm Pharmaceuticals 297 participants Est. completion 2023-12-31 1 site

Other conditions: Chronic Liver Disease
View official trial listing →
Status unknown NCT NCT05902468

Ursodeoxycholic Acid as add-on Therapy in Type 2 Diabetes Mellitus

Not yet reported, Not yet reported Tanta University 88 participants Est. completion 2024-11-28 2 sites

Type 2 diabetes
View official trial listing →
Completed NCT NCT05973370

Evaluating the Effect of Ursodeoxycholic Acid in Patients With Rheumatoid Arthritis

Not yet reported Tanta University 60 participants Est. completion 2024-05-30 1 site

Other conditions: Rheumatoid Arthritis
View official trial listing →
Completed NCT NCT06091787

Effect of Ursodeoxycholic Acid Supplementation on Liver Regeneration on Right Lobe Donor Hepatectomy

Not yet reported Institute of Liver and Biliary Sciences, India 90 participants Est. completion 2024-11-30 1 site

Other conditions: Liver Regeneration, Ursodeoxycholic Acid, Partial Liver Resection
View official trial listing →
Completed NCT NCT06120036

Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Not yet reported Massachusetts General Hospital 20 participants Est. completion 2025-01-09 1 site

Other conditions: Neurofibromatosis 1
View official trial listing →
Completed NCT NCT06127355

Gestational Treatment With Ursodeoxycholic Acid Compared to Placebo to Reduce Severity of Gestational Diabetes Mellitus Diagnosed at 24-28 Weeks' Gestation

Not yet reported Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia 113 participants Est. completion 2022-05-10 1 site

Other conditions: Gestational Diabetes
View official trial listing →
Completed NCT NCT06132165

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Not yet reported Massachusetts General Hospital 13 participants Est. completion 2025-07-31 1 site

Other conditions: Neurofibromatosis 1
View official trial listing →
Completed NCT NCT06180057

Bioequivalence Study to Compare Chenodeoxycholic Acid Capsules (250mg Chenodeoxycholic Acid) Versus Chenodeoxycholic Acid Leadiant 250 mg Hard Capsules (250mg Chenodeoxycholic Acid)

Not yet reported Humanis Saglık Anonim Sirketi 24 participants Est. completion 2022-08-15 1 site

Other conditions: Cerebrotendinous Xanthomatoses
View official trial listing →
Withdrawn NCT NCT06260748

A Study of Chenodeoxycholic Acid (CDCA) in Newly Diagnosed Participants With Cerebrotendinous Xanthomatosis (CTX)

Not yet reported Leadiant Biosciences, Inc. Est. completion 2025-12-31 1 site

Other conditions: Cerebrotendinous Xanthomatoses
View official trial listing →
Active, not recruiting NCT NCT06278090

Impact of Ursodeoxycholic Acid Treatment on the Gallbladder Polyp Evolution

Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz 36 participants Est. completion 2027-07 1 site

Other conditions: Gallbladder Polyp
View official trial listing →
Enrolling by invitation NCT NCT06300502

Assessing the Efficacy of Repeat, Monthly Treatments of Deoxycholate for NF1 Associated Cutaneous Neurofibromas (cNFs)

Not yet reported Massachusetts General Hospital 15 participants Est. completion 2027-02 1 site

Other conditions: Neurofibromas, Cutaneous, Neurofibromatosis 1
View official trial listing →
Completed NCT NCT06414512

Optimizing the Dose of Flucytosine for the Treatment of Cryptococcal Meningitis

Not yet reported University of Minnesota 48 participants Est. completion 2024-10-02 2 sites

Other conditions: Cryptococcal Meningitis
View official trial listing →
Completed NCT NCT06509438

Effectiveness and Safety Evaluation of Embella (Deoxycholic Acid, by Espad Pharmed Co.) in Management of Submental Fat

Not yet reported Espad Pharmed 20 participants Est. completion 2024-01-01 1 site

Other conditions: Submental Fullness
View official trial listing →
Completed NCT NCT06517862

Efficacy & Safety of Oral Adjuvants to Phototherapy in Neonatal Hyperbilirubinemia

Not yet reported Amira Adel Fouly 140 participants Est. completion 2026-05-01 1 site

Other conditions: Neonatal Hyperbilirubinemia
View official trial listing →
Not yet recruiting NCT NCT06525389

Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)

Not yet reported Duke University 428 participants Est. completion 2031-09-01 5 sites Stand-alone

Other conditions: Talaromycosis
View official trial listing →
Completed NCT NCT06591455

A Pilot Study of Fenofibrate and Ursodeoxycholic Acid in the Treatment of Newly Diagnosed Primary Biliary Cholangitis

Not yet reported Han Ying 30 participants Est. completion 2025-08-18 1 site

Other conditions: Primary Biliary Cholangitis (PBC)
View official trial listing →
Enrolling by invitation NCT NCT06591468

A Multicenter, Randomized, Controlled Trial of Prednisone Combined With Ursodeoxycholic Acid in the Treatment of Primary Biliary Cholangitis With Moderate to Severe Interface Hepatitis Characteristics

Not yet reported, Not yet reported Han Ying 244 participants Est. completion 2027-12-31 2 sites

Other conditions: Primary Biliary Cholangitis (PBC)
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Not yet recruiting NCT NCT06629909

Safety and Feasibility of Human Umbilical Cord Mesenchymal Stem Cell-Derived Secretome in the Treatment of Liver Cirrhosis: a Comprehensive Evaluation of Fibrosis Reduction, Immunomodulation, and Hepatic Regeneration: a Single Center, Randomized, Phase I Clinical Trial

Not yet reported Baermed 54 participants Est. completion 2026-10-31 1 site

Other conditions: Liver Cirrhosis
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Completed NCT NCT06783621

A Study to Evaluate Patient Satisfaction With the Overall Face and Neck Appearance After Combined Treatment of OnabotulinumtoxinA, JUVÉDERM® Products, KYBELLA, CoolSculpting Elite and SkinMedica Products

Not yet reported AbbVie 130 participants Est. completion 2026-03-20 10 sites Stand-alone

Other conditions: Facial Contouring
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Not yet recruiting NCT NCT06842472

PD-L1 Inhibitor + RT ± Ursodeoxycholic Acid in Recurrent/Metastatic HER2-Neg Breast Cancer

Not yet reported Cancer Institute and Hospital, Chinese Academy of Medical Sciences 70 participants Est. completion 2029-12

Other conditions: Breast Cancer
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Not yet recruiting NCT NCT06884748

Prevention of Recurrence of Clostridioides Difficile Colitis With Ursodeoxycholic Acid (UCDA) as a Supplement to Standard Therapy

Not yet reported Medical College of Wisconsin 30 participants Est. completion 2028-05-01 1 site

Other conditions: Clostridioides Difficile Infection
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Active, not recruiting NCT NCT06918080

Hepatoprotective Measures for Children at High Risk of NAFLD

Not yet reported Ain Shams University 200 participants Est. completion 2025-07 2 sites

MASLD Other conditions: Obesity and Overweight, Acute Lymphoblastic Leukemia
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Not yet recruiting NCT NCT06926569

Single High-dose of Liposomal Amphotericin B in Combination With B/F/TAF for HIV/AIDS-associated Talaromycosis

Not yet reported Shanghai Public Health Clinical Center 116 participants Est. completion 2026-05-01 Stand-alone

Other conditions: HIV/AIDS-associated Talaromycosis
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Completed NCT NCT07004010

Evaluating the Efficacy and Safety of Embella (Deoxycholic Acid, Produced by Espad Pharmed Co.) for the Treatment of Flank Fat

Not yet reported Espad Pharmed 30 participants Est. completion 2024-12-30 1 site

Other conditions: Flank Fat
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Completed NCT NCT07072949

The Impact of Ursodeoxycholic Acid and Probiotics on Metabolic Outcomes in Type 2 Diabetic Patients Taking Metformin

Not yet reported University of Banja Luka 90 participants Est. completion 2024-01-31 1 site

Type 2 diabetes
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Terminated NCT NCT07102979

Remedial Mechanism of Simvastatin and Ursodeoxycholic Acid in Liver Cirrhosis: Crosstalk of Bile Secretion, Gut Microbiome, and Host Immune Response

Not yet reported Chang Gung Memorial Hospital 19 participants Est. completion 2025-12-31 1 site

Other conditions: Liver Fibrosis
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Active, not recruiting NCT NCT07191756

Amphotericin B Versus Isavuconazole for Mucormycosis: A Comparative Efficacy and Safety Study

Qiu Ye 150 participants Est. completion 2025-09-25 1 site

Other conditions: Mucormycosis
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Not yet recruiting NCT NCT07273734

UDCA to Prevent Post-TIPS Hepatic Encephalopathy

Not yet reported West China Hospital 270 participants Est. completion 2027-12-31 1 site

Other conditions: Hepatic Encephalopathy (HE), TIPS
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Not yet recruiting NCT NCT07525401

Comparative Evaluation of Oral Ursodeoxycholic Acid in Reducing Bilirubin Levels Among Patients With Acute Viral Hepatitis

Not yet reported Combined Military Hospital, Pakistan 88 participants Est. completion 2026-10

Other conditions: Hepatitis A, Hepatitis E Virus Infection
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Not yet recruiting NCT NCT07664020

Effect of Ursodeoxycholic Acid Supplementation on Liver Regeneration in Adult Living Donor Liver Transplant (LDLT) Recipients.

Not yet reported Institute of Liver and Biliary Sciences, India 130 participants Est. completion 2027-11-01 1 site

Other conditions: Chronic Liver Disease
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Completed NCT NCT07743788

Efficacy, Satisfaction, and Safety of the Mesolipo® Protocol for the Treatment of Localized Adiposity

Not yet reported Antony de Paula Barbosa 12 participants Est. completion 2025-06-30 1 site Stand-alone

Other conditions: Localized Adiposity
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Completed NCT NCT07790757

Efficacy of Topical Insulin Gel as a Coupling Medium in Phonophoresis-Assisted Physiotherapy vs Liposomal Insulin in Management of Joint Inflammation

Not yet reported Deraya University 60 participants Est. completion 2026-02-01 1 site Stand-alone

Other conditions: Joint Inflammation
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Not yet recruiting NCT NCT07852780

Effect of Adjunctive Ursodeoxycholic Acid on Oxidative Stress, Inflammation, and Organ Dysfunction in Adults With Sepsis

Not yet reported, Not yet reported Tanta University 80 participants Est. completion 2027-10-01

Other conditions: Sepsis
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Completed NCT NCT07867366

Effect of Ursodeoxycholic Acid on Indirect Hyperbilirubinemia in Neonates Treated With Phototherapy

Not yet reported Muhammad Aamir Latif 220 participants Est. completion 2026-07-31 1 site

Other conditions: Hyperbilirubinemia Indirect
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Completed NCT NCT07880301

Safety and Efficacy of Deoxycholate Treatment of Small Fatty Deformities ( SFD)

Not yet reported The Maas Clinic 37 participants Est. completion 2021-12-25 1 site Stand-alone

Other conditions: Deformity; Skin, Fat Redistribution, Lipodystrophy
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Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

ClinicalTrials.gov — NCT07880301

Also known as: Kybella, Deoxycholate, Sodium deoxycholate

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No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.