About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Intranasal insulin
- Company
- Centre for Addiction and Mental Health
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 18 recruiting
Efficacy results: Not yet reported
18 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 26, 2026
Find a Clinical Trial Near Me
See recruiting studies for Intranasal insulin and check eligibility with the study team.
Trial details
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Recruiting NCT NCT03087032
Liraglutide-bolus vs Glargine-bolus Therapy in Overweight/Obese Type 2 Diabetes Patients (LiraGooD)
Not yet reported The First Affiliated Hospital of Xiamen University 164 participants Est. completion 2025-02-10 1 siteType 2 diabetes Other conditions: Overweight and Obesity, Hyperglycaemia (Diabetic)View official trial listing → -
Recruiting NCT NCT03463564
Insulin Pump vs Multiple Daily Injections of Insulin and Glyco-metabolic Control in Type 1 Diabetic Patients
Not yet reported University of Campania Luigi Vanvitelli 150 participants Est. completion 2026-12 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Recruiting NCT NCT05266417
Intranasal Insulin and Glutathione as an Add-On Therapy in Parkinson's Disease
Not yet reported Gateway Institute for Brain Research 56 participants Est. completion 2027-11-30 4 sitesOther conditions: Parkinson DiseaseView official trial listing → -
Recruiting NCT NCT05988632
Intranasal Insulin for Treatment of Alcohol Use Disorder
Not yet reported, Not yet reported Brown University 40 participants Est. completion 2027-01-31 1 siteAlcohol use disorderView official trial listing → -
Recruiting NCT NCT06039787
Exercise Training on Brain Insulin Responsiveness
Not yet reported University Hospital Tuebingen 40 participants Est. completion 2026-12-31 1 siteOther conditions: Insulin Resistance, ObesityView official trial listing → -
Recruiting NCT NCT06072963
COMMETS- Combination MCI Metabolic Syndrome
Not yet reported Rutgers, The State University of New Jersey 80 participants Est. completion 2028-12-01 1 site Added to GLP-1Metabolic syndrome Other conditions: Alzheimer Disease, Mild Cognitive ImpairmentView official trial listing → -
Recruiting NCT NCT06251635
Effects of Antipsychotics on Brain Insulin Action in Females
Not yet reported Centre for Addiction and Mental Health 15 participants Est. completion 2026-08-01 1 site Stand-aloneType 2 diabetes Other conditions: Insulin Resistance, Menstrual Cycle, AntipsychoticsView official trial listing → -
Recruiting NCT NCT06280703
A Study of LY3938577 in Healthy Participants and Participants With Type 1 Diabetes Mellitus (T1DM)
Not yet reported Eli Lilly and Company 118 participants Est. completion 2026-09 1 siteOther conditions: Healthy, Type 1 Diabetes MellitusView official trial listing → -
Recruiting NCT NCT06419777
Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes
Not yet reported Thomas Jefferson University 430 participants Est. completion 2026-05 2 sitesOther conditions: Gestational Diabetes, Pregnancy RelatedView official trial listing → -
Recruiting NCT NCT06419803
Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)
Not yet reported Thomas Jefferson University 430 participants Est. completion 2026-05 2 sitesOther conditions: Gestational Diabetes, Pregnancy RelatedView official trial listing → -
Recruiting NCT NCT06445946
DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes
Not yet reported Ohio State University 1572 participants Est. completion 2030-12 24 sites Stand-aloneOther conditions: Gestational Diabetes Mellitus, Pregnancy, High RiskView official trial listing → -
Recruiting NCT NCT06532461
A Trial of Three- and Seven-days Insulin Infusions Set
Not yet reported Steno Diabetes Center Copenhagen 80 participants Est. completion 2026-12-31 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Recruiting NCT NCT06945406
A Study of LY4057996 in Healthy Participants and Participants With Type 1 and Type 2 Diabetes
Not yet reported Eli Lilly and Company 124 participants Est. completion 2026-12 1 siteType 2 diabetes Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Recruiting NCT NCT07109245
Do Antipsychotics Block Insulin Action in the Brain: is it a Class Effect?
Not yet reported Centre for Addiction and Mental Health 35 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Brain Insulin Sensitivity, Healthy Controls, CognitionView official trial listing → -
Recruiting NCT NCT07171684
Single vs Multi-Dose Insulin for Glycemic Control (SUGAR)
Not yet reported Rutgers, The State University of New Jersey 176 participants Est. completion 2027-05-15 2 sitesOther conditions: Diabetes in Pregnancy, Gestational DiabetesView official trial listing → -
Recruiting NCT NCT07384052
Safety and Feasibility of Intranasal Insulin in Patients With Spinal Cord Injury
Not yet reported HealthPartners Institute 12 participants Est. completion 2027-01 1 site Stand-aloneOther conditions: Spinal Cord InjuryView official trial listing → -
Recruiting NCT NCT07422220
Long-Term Effects of Walnut Consumption on Brain Function
Not yet reported Maastricht University Medical Center 55 participants Est. completion 2027-08 1 siteOther conditions: Healthy, Brain Insulin Sensitivity, Cerebral Blood Flow, Brain Vascular Function, Satiety and Food Intake, Food Reward, Cognitive Performance, Abdominal Obesity, Cognitive DeclineView official trial listing → -
Recruiting NCT NCT07675499
Exercise and Intranasal Insulin in Type 2 Diabetes
Not yet reported, Not yet reported Rutgers, The State University of New Jersey 60 participants Est. completion 2029-05-31 4 sitesType 2 diabetes Other conditions: Insulin Sensitivity/Resistance, Cognition, Brain Blood FlowView official trial listing → -
Completed NCT NCT00036504
Efficacy and Safety of Twice-Daily Insulin Lispro Low Mixture Compared to a Once-Daily Long Acting Insulin Comparator in Patients Who Have Been Using One or More Oral Antihyperglycemic Agents Without Insulin
Not yet reported Eli Lilly and Company 100 participants Est. completion 2002-08 13 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00046501
Compare Blood Sugar Level Between Lantus in the Morning and Other Insulins in Type 1 Diabetes Adolescents
Not yet reported Sanofi 250 participants 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00063128
Safety and Efficacy of Human Insulin Inhalation Powder in Patients With Type 1 Diabetes Mellitus.
Not yet reported Eli Lilly and Company 119 participants Est. completion 2004-04 25 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00071448
Insulin Aspart vs. Insulin Lispro vs. Regular Insulin in Paediatric Population
Not yet reported Novo Nordisk A/S 378 participants Est. completion 2004-06 76 sitesOther conditions: Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00097071
Safety and Efficacy of NovoLog vs. Humalog in Insulin Pumps in Children and Adolescents
Not yet reported Novo Nordisk A/S 299 participants Est. completion 2006-05 52 sitesOther conditions: Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00110370
Comparing Pre-Mixed Insulin With Insulin Glargine Combined With Rapid-Acting Insulin in Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 300 participants Est. completion 2006-04 48 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00115570
Comparison of the Ability of Glulisine With Lispro to Control Type 1 Diabetes Mellitus in Children and Adolescents
Not yet reported Sanofi 572 participants Est. completion 2006-11 1 siteOther conditions: Diabetes Mellitus, Insulin-DependentView official trial listing → -
Completed NCT NCT00135941
Insulin Glargine Plus Insulin Glulisine Multiple Daily Injections (MDI) Versus Premix Insulin Treatment in Subjects With Diabetes Mellitus (Type 1 or Type 2)
Not yet reported Sanofi 582 participants Est. completion 2007-09 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00191178
Effects of Insulin in Perceived Mood Symptoms in Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 60 participants Est. completion 2005-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00191282
Hyperglycemia and Cardiovascular Outcomes With Type 2 Diabetes
Not yet reported Eli Lilly and Company 1116 participants Est. completion 2007-10 17 sitesType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00191464
Long-Term Effects of Insulin Plus Metformin Regimens on the Overall and Postprandial Glycemic Control of Patients With Type 2 Diabetes
Not yet reported Eli Lilly and Company 320 participants Est. completion 2005-09 7 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00191581
Local Registration Trial in China Humalog Mix 50
Not yet reported Eli Lilly and Company 120 participants Est. completion 2006-04 2 sitesType 2 diabetes Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT00223613
Intranasal Insulin for Prevention of Type 1 Diabetes
Not yet reported University of Turku 240 participants Est. completion 2005-08 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Withdrawn NCT NCT00228904
Effects of Pulsatile Intravenous Insulin Delivery on Diabetic Neuropathy in pATIENTS (Pts) With Type 1 and Type 2 Diabetes
Not yet reported, Not yet reported Florida Atlantic University Est. completion 2011-10 1 siteOther conditions: Diabetic NeuropathyView official trial listing → -
Completed NCT NCT00231725
Complaints Associated With Use of Pre-Filled Pen B With Type 2 Diabetics on Twice-Daily Insulin
Not yet reported Eli Lilly and Company 370 participants Est. completion 2006-04 4 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00279201
The DURABLE Trial: Evaluating the Durability of Starter Insulin Regimens in Patients With Type 2 Diabetes (IOOV)
Not yet reported Eli Lilly and Company 2091 participants Est. completion 2009-11 199 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00290979
Efficacy and Safety of Insulin Glulisine in Type 1 Diabetes Mellitus
Not yet reported Sanofi 250 participants 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00297583
Insulin Glulisine in Type 1 Diabetes Mellitus
Not yet reported SanofiOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00310297
Insulin Glulisine in Type 2 Diabetes Mellitus
Not yet reported SanofiType 2 diabetesView official trial listing → -
Completed NCT NCT00311077
Insulin Glulisine in Healthy Lean and Obese Subjects
Not yet reported SanofiOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00311818
Insulin Glargine in Type 2 Diabetes Mellitus
Not yet reported SanofiType 2 diabetesView official trial listing → -
Completed NCT NCT00314314
The Effect of Intranasal Insulin on Neurocognitive Function in Euthymic Patients With Bipolar Disorder
Not yet reported University Health Network, Toronto 60 participants Est. completion 2009-03 1 site Stand-aloneOther conditions: Bipolar DisorderView official trial listing → -
Completed NCT NCT00336674
Trial of Intranasal Insulin in Children and Young Adults at Risk of Type 1 Diabetes
Not yet reported Melbourne Health 110 participants Est. completion 2019-11-13 6 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00348374
Exubera vs Lispro in a Lantus-based Regimen for Improved Glycemic Control in Type 2 Diabetes
Not yet reported Pfizer 191 participants Est. completion 2008-08 63 sitesOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT00356421
A Clinical Trial Comparing Efficacy and Safety of Exubera® and Humalog®
Not yet reported Pfizer 58 participants Est. completion 2008-06 23 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00377858
Comparison of Two Approaches to Insulin Therapy in Patients With Type 2 Diabetes (IOOX)
Not yet reported Eli Lilly and Company 484 participants Est. completion 2008-09 25 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00393705
Lispro Mid Mixture (MM) Intensive Mixture Therapy With Progressive Dose-Titration of Lispro Low Mixture (LM) or Biphasic Insulin Aspart 30/70 (S019)
Not yet reported Eli Lilly and Company 302 participants Est. completion 2009-03 9 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00420095
A Study for Patients With Diabetes Mellitus (IOPA)
Not yet reported Eli Lilly and Company 117 participants Est. completion 2008-01 4 sitesType 2 diabetes Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Terminated NCT NCT00428207
Glycemic Stability of Insulin Aspart Versus Insulin Lispro in Insulin Pump Therapy
Not yet reported Joslin Diabetes Center 4 participants Est. completion 2008-08 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00438568
SNIFF 120: Study of Nasal Insulin to Fight Forgetfulness (120 Days)
Not yet reported University of Washington 173 participants Est. completion 2011-12 1 siteOther conditions: Mild Cognitive Impairment, Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00442767
Post-meal Insulin Dosing With Adjuvant Pre-meal Pramlintide in Children With Type 1 Diabetes Mellitus
Not yet reported Montefiore Medical Center 8 participants Est. completion 2009-02 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00461331
Comparison of Insulins Aspart and Lispro in Insulin Pumps
Not yet reported Tulane University Health Sciences Center 20 participants Est. completion 2008-08 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Terminated NCT NCT00464854
Glucose Control With Multiple Daily Insulin Injections In Diabetic Patients Hospitalized In A General Medicine Ward
Not yet reported Assaf-Harofeh Medical Center 100 participants Est. completion 2006-09 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00467376
Insulin Glulisine, Insulin Lispro and Insulin Glargine in Type 1 or 2 Diabetes Mellitus
Not yet reported Sanofi 485 participants 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00467649
A Study to Characterize Regimens of Basal Insulin Intensified With Either Symlin® or Rapid Acting Insulin in Patients With Type 2 Diabetes
Not yet reported AstraZeneca 112 participants Est. completion 2008-04 37 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00468754
A Study Comparing Continuous Subcutaneous Insulin Infusion With Multiple Daily Injections With Insulin Lispro and Glargine
Not yet reported Hoffmann-La Roche 50 participants Est. completion 2005-05 4 sitesOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT00487240
Comparison of Two Basal Insulin Therapies for Patients With Type 1 Diabetes
Not yet reported Eli Lilly and Company 387 participants Est. completion 2008-08 28 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00494013
Comparison of Two Basal Insulins for Patients With Type 2 Diabetes (IOOY)
Not yet reported Eli Lilly and Company 442 participants Est. completion 2008-09 56 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT00505882
Efficacy of Pramlintide on Prevention of Weight Gain Early Onset of Type 1 Diabetes
Not yet reported University of Texas Southwestern Medical Center Est. completion 2008-12 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00510952
Comparison of Two Basal Insulins for Patients With Type 2 Diabetes on Anti-Hyperglycemic Medications (IOPE)
Not yet reported Eli Lilly and Company 471 participants Est. completion 2008-10 17 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00513201
Lyspro Insulin vs Regular Insulin in Cirrhotic Patients
Not yet reported University of Campania Luigi Vanvitelli 1 siteOther conditions: Diabetes Mellitus, CirrhosisView official trial listing → -
Completed NCT NCT00537251
32 Week, Open, Randomized, 2 Way Cross Over Multicentre Trial to Compare Safety & Efficacy of Combination of HOE901 Insulin Analogue Once Daily at Bedtime + Lispro Insulin Before Meals vs NPH Insulin (Twice a Day) + Regular in Type 1 Diabetes Mellitus
Not yet reported Sanofi 80 participants Est. completion 2004-02Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00540709
PUMP STUDY MDI Lantus/Lispro vs Continuous Insulin+Lispro
Not yet reported Sanofi 58 participants Est. completion 2003-09Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00548808
A Study for Type 2 Diabetic Patients
Not yet reported Eli Lilly and Company 426 participants Est. completion 2009-08 25 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00551356
Lispro Mix 25 vs. Glargine in Type 2 Diabetics
Not yet reported Eli Lilly and Company 53 participants Est. completion 2003-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00551538
24 Hour Plasma Glucose Profiles Comparing Lispro Mix 75/25 vs. Glargine
Not yet reported Eli Lilly and Company 15 participants Est. completion 2004-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00553488
Feasibility Study of the Effect of Intra-Dermal Insulin Injection on Blood Glucose Levels After Eating
Not yet reported Becton, Dickinson and Company 30 participants Est. completion 2008-01 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00560417
Comparison of Two Basal Insulins for Patients With Type 2 Diabetes Taking Oral Diabetes Medicines and Exenatide
Not yet reported Eli Lilly and Company 339 participants Est. completion 2009-12 52 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00570050
Effect of Intranasal Insulin on Depressive Symptoms in Major Depressive Disorder
Not yet reported University Health Network, Toronto 35 participants Est. completion 2014-09 1 site Stand-aloneOther conditions: Major Depressive DisorderView official trial listing → -
Completed NCT NCT00574405
Preservation of Pancreatic Beta Cell Function Through Insulin Pump Therapy
Not yet reported Arkansas Children's Hospital Research Institute 24 participants Est. completion 2011-03 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00575666
Intranasal Insulin Treatment in Patients With Schizophrenia
Not yet reported University of Massachusetts, Worcester 45 participants Est. completion 2010-09 1 site Stand-aloneOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT00581867
Memory and Insulin in Early Alzheimer's Disease
Not yet reported, Not yet reported Jeff Burns, MD 31 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00607087
Effect of Insulin Glulisine Compared to Insulin Aspart and Insulin Lispro When Administered by Continuous Subcutaneous Insulin Infusion (CSII) on Specific Pump Parameters in Patient With Type 1 Diabetes Mellitus
Not yet reported Sanofi 289 participants Est. completion 2009-06 12 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00624767
A Study to Evaluate the Effect of Nasal Insulin on Postprandial Glycemic Control in Type 2 Diabetic Patients
Not yet reported Nastech Pharmaceutical Company, Inc. 18 participants Est. completion 2008-05 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00641407
Bedtime Insulins and Oral Antihyperglycemic Drugs in Type 2 Diabetes
Not yet reported University of Campania Luigi Vanvitelli 100 participants Est. completion 2008-03 1 siteType 2 diabetes Other conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT00646581
Effect of Single Dose Intranasal Insulin On Cognitive Function
Not yet reported University of Massachusetts, Worcester 30 participants Est. completion 2010-01 1 site Stand-aloneOther conditions: Schizophrenia, Schizoaffective DisorderView official trial listing → -
Completed NCT NCT00652288
Evaluation of Pharmacokinetics and Pharmacodynamic Properties of Rapid-Acting Insulin Analogs
Not yet reported Yale University 36 participants Est. completion 2011-09Other conditions: Diabetes Mellitus, Type IView official trial listing → -
Completed NCT NCT00662857
A Study Designed to Compare 2 Dose Strengths of TI Inhalation Powder in Adults With Type 1 Diabetes Mellitus and to Compare One of Those Formulations (30Units) With an Injection of Insulin Lispro
Not yet reported Mannkind Corporation 29 participants Est. completion 2008-12 2 sitesOther conditions: Diabetes Mellitus: Type 1View official trial listing → -
Completed NCT NCT00664534
Pre-Mix Insulin Lispro Treatment for Type 2 Diabetes Patients Who Consume a Light Breakfast
Not yet reported Eli Lilly and Company 344 participants Est. completion 2010-11 27 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00666718
A Comparison Study of Basal Bolus Therapies Together With Lispro Insulin in Type 2 Diabetes Patients
Not yet reported Eli Lilly and Company 374 participants Est. completion 2010-02 50 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT00700622
Safety and Efficacy of Technosphere® Insulin Inhalation Powder and Lantus® Compared to Humalog® and Lantus® Over 16-Weeks
Not yet reported Mannkind Corporation 130 participants Est. completion 2010-03 22 sites Stand-aloneOther conditions: Diabetes, Type 1View official trial listing → -
Completed NCT NCT00705536
Pharmacokinetic (PK), Pharmacodynamic (PD), and Safety Study of Subcutaneously Administered Humalog® With and Without Recombinant Human Hyaluronidase (rHuPH20)and Humulin-R® With and Without rHuPH20
Not yet reported Halozyme Therapeutics 26 participants Est. completion 2008-02 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT00747006
Safety and Efficacy of Technosphere® Insulin Inhalation Powder (TI Inhalation Powder)When an Optimal Dose is Taken With Varied Carbohydrate Intake
Not yet reported Mannkind Corporation 18 participants Est. completion 2011-05 1 siteType 2 diabetes Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00774800
Phase II Pharmacokinetics Study of Humalog and Humulin-R With and Without rHuPH20 in Type 1 Diabetes Mellitus
Not yet reported Halozyme Therapeutics 22 participants Est. completion 2009-03 1 site Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00803972
Dose-Ranging, Pharmacokinetic (PK), Glucodynamic (GD), Safety and Tolerability Study of Subcutaneously (SC) Administered Humulin R and Humalog With or Without rHuPH20
Not yet reported Halozyme Therapeutics 42 participants Est. completion 2009-08-28 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT00806975
Comparison of Novo Rapid 30 Mix Injection FlexPen® and Humalog 25 Mix Injection KwikPen® in Type 2 Diabetic Patients
Not yet reported Nagaoka Red Cross Hospital 200 participants Est. completion 2009-06 1 siteType 2 diabetes Other conditions: Diabetes ComplicationsView official trial listing → -
Completed NCT NCT00810589
A Randomised, Single Centre, Double-Blind, Two-Period Crossover, Glucose Clamp Trial
Not yet reported Medical University of Graz 30 participants Est. completion 2008-12 1 siteOther conditions: Diabetes, Type IView official trial listing → -
Completed NCT NCT00841919
Insulin Therapy in the Hospital Comparing Two Protocols
Not yet reported Cook County Health 60 participants Est. completion 2009-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00849576
Effect of Treatment With Insulin VIAjectTM Compared to Regular Human Insulin and Insulin Lispro on Mealtime Blood Vessel Stress in Patients With Type 2 Diabetes Mellitus.
Not yet reported Biodel 15 participants Est. completion 2008-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00850096
Effects of Nasulin Versus Placebo on Blood Glucose Control in Patient Volunteers With Type 2 Diabetes Mellitus
Not yet reported CPEX Pharmaceuticals Inc. 94 participants Est. completion 2010-03 21 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT00850161
Intranasal Insulin and Its Effect on Postprandial Metabolism in Comparison to Subcutaneous Insulin
Not yet reported CPEX Pharmaceuticals Inc. Est. completion 2010-09 Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00862849
Pharmacokinetic and Glucodynamic Crossover Study of Subcutaneously (SC) Administered Insulin Lispro + Recombinant Human Hyaluronidase (rHuPH20) and Regular Human Insulin + rHuPH20 Compared to Insulin Lispro Alone
Not yet reported Halozyme Therapeutics 22 participants Est. completion 2009-08 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00874809
Diabetes Mellitus Type 2 Basal Insulin Dosing Requirements Study
Not yet reported Diabetes Care Center 30 participants Est. completion 2011-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00883558
Safety Study of Subcutaneously-Injected Prandial INSULIN-PH20 NP Compared to Insulin Lispro Injection in Participants With Type 1 Diabetes Mellitus
Not yet reported Halozyme Therapeutics 48 participants Est. completion 2010-04 8 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Withdrawn NCT NCT00916201
Evaluation Study of New Compounds With Potential Use in Schizophrenia
Not yet reported Central Institute of Mental Health, Mannheim Est. completion 2025-01-31 1 site Stand-aloneOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT00916357
Liquid Meal Study With Insulin Lispro With/Without Recombinant Human Hyaluronidase PH20 (rHuPH20) and Regular Human Insulin With rHuPH20 to Compare Pharmacokinetics, Postprandial Glycemic Response, and Optimal Insulin Dose in Participants With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Halozyme Therapeutics 23 participants Est. completion 2009-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00927524
Insulin Exposure and Glucose Response to Meals in Type 1 Diabetic Subjects Administered Two Different Insulin Regimens Compared to the Endogenous Insulin Exposure and Glucose Response to Meals In Healthy Adult Controls
Not yet reported Vanderbilt University 24 participants Est. completion 2010-12Other conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00960661
A Trial Comparing Two Therapies: Basal Insulin/Glargine, Exenatide and Metformin Therapy (BET) or Basal Insulin/Glargine, Bolus Insulin Lispro and Metformin Therapy (BBT) in Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 1036 participants Est. completion 2012-08 95 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00971997
A Study of Insulin Lispro Mix in Type 2 Diabetic Asian Patients
Not yet reported Eli Lilly and Company 135 participants Est. completion 2011-04 14 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00976391
A Study to Determine the Safety and Efficacy of Albiglutide Administered in Combination With Insulin Glargine
Not yet reported GlaxoSmithKline 586 participants Est. completion 2012-05 209 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00977808
Pilot Study of Closed-Loop Glucose Control in People With Type 1 Diabetes (BPK004)
Not yet reported University of Virginia 12 participants Est. completion 2009-02 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00979875
A Pharmacokinetic and Glucodynamic Study of Subcutaneously Administered Insulin Analogs With rHuPH20 Compared to Insulin Analogs Alone
Not yet reported Halozyme Therapeutics 14 participants Est. completion 2010-05 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00985712
A Study on the Effect of 2 Pen Devices on HbA1c
Not yet reported Eli Lilly and Company 263 participants Est. completion 2011-07 29 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00993473
6-month Comparison of Morning Lantus Versus Neutral Protamine Hagedorn Insulin in Young Children With Type 1 Diabetes
Not yet reported Sanofi 125 participants Est. completion 2011-03 61 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01000922
A Study Comparing the Pharmacodynamic Properties of Insulin VIAJECT™, Regular Human Insulin, and Insulin Lispro
Not yet reported Biodel 24 participants Est. completion 2008-01 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT01023165
Effects of Intensive Bolus Intravenous Insulin Delivery on Metabolic Integrity in Type 1 and Type 2 Diabetes
Not yet reported Global Infusion and Aspiration Systems, LLC 2000 participants Est. completion 2015-11 1 site Stand-aloneOther conditions: Diabetes Mellitus, Metabolic IntegrityView official trial listing → -
Terminated NCT NCT01035801
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Insulin (IN-105) in Type 1 Diabetes Patients
Not yet reported Biocon Limited 20 participants Est. completion 2011-03-12 5 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT01045954
A Study of the Rules for Insulin Dosing in Patients Using Multiple Daily Injections
Not yet reported Diabetes Care Center 50 participants Est. completion 2010-10 1 siteOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Withdrawn NCT NCT01067118
A Randomized Control Trial Comparing Linjeta Versus Humalog in Pumps: Effect on Postprandial Blood Sugars.
Not yet reported Stanford University Est. completion 2011-06 2 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01068860
To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies
Not yet reported Novartis 246 participants Est. completion 2010-08 52 sitesType 2 diabetesPrediabetesView official trial listing → -
Completed NCT NCT01109316
Insulin Lispro 6 Days Versus Insulin Aspart 6 Days in Pump Use
Not yet reported Eli Lilly and Company 132 participants Est. completion 2011-08 11 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01110746
To Evaluate the Effect on Post-prandial Glycemia Safety, and Tolerability of Viaject 7 vs. Lispro Insulin During Subcutaneous Insulin Pump Therapy
Not yet reported Biodel 20 participants Est. completion 2010-06 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01120444
Study on the Effects on Blood Glucose Following Intradermal and Subcutaneous Dosing of Insulin in Diabetic Patients
Not yet reported, Not yet reported Becton, Dickinson and Company 20 participants Est. completion 2010-10 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01121835
Insulins Glargine and gluLisine strAtegy Versus Premixed Insulin strAteGy: a cOmparative Study
Not yet reported Sanofi 934 participants Est. completion 2012-03 96 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01133392
Bioequivalence of Two Lispro Formulations
Not yet reported Eli Lilly and Company 41 participants Est. completion 2010-08 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT01134107
Insulin Lispro 6 Days Versus Insulin Aspart 6 Days in Pump Use
Not yet reported Eli Lilly and Company 133 participants Est. completion 2011-12 15 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Terminated NCT NCT01136746
Hospital Management of Hyperglycemia Study of Insulin Glargine Plus Insulin Lispro Versus Human Regular Insulin
Not yet reported Eli Lilly and Company 16 participants Est. completion 2011-11 12 sitesOther conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT01147627
Effect of Different Interventions on Glycemic Control and β-cell Function in Newly Diagnosed Type 2 Diabetic Patients
Not yet reported Sun Yat-sen University 416 participants Est. completion 2012-12 25 sitesType 2 diabetes Other conditions: Newly DiagnosedView official trial listing → -
Status unknown NCT NCT01149005
Cystic Fibrosis (CF) Exacerbation and Insulin Treatment
Not yet reported Hadassah Medical Organization 30 participants Est. completion 2015-12 1 site Stand-alonePrediabetes Other conditions: Cystic Fibrosis, Pulmonary ExacerbationView official trial listing → -
Completed NCT NCT01159938
A Study of Postprandial Hyperglycemia in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 72 participants Est. completion 2013-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01175811
A Study Comparing Insulin Intensification Therapies in Patients With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 402 participants Est. completion 2012-11 14 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01175824
Comparison of the Efficacy and Safety of Two Insulin Intensification Strategies
Not yet reported Eli Lilly and Company 478 participants Est. completion 2012-11 18 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01184014
Hospital Insulin Protocol Aims for Glucose Control in Corticosteroid-induced Hyperglycemia
Not yet reported HealthPartners Institute 72 participants Est. completion 2012-08 1 siteOther conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT01191268
A Study in Participants With Type 2 Diabetes Mellitus (AWARD-4)
Not yet reported Eli Lilly and Company 884 participants Est. completion 2012-09 101 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01194245
Safety/Efficacy Study of Subcutaneously Injected Prandial Insulins Compared to Insulin Lispro Alone in Participants With Type 1 Diabetes Mellitus
Not yet reported Halozyme Therapeutics 135 participants Est. completion 2011-08 19 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01194258
Safety/Efficacy Study of Subcutaneously Injected Prandial Insulins Compared to Insulin Lispro Alone in Patients With Type 2 Diabetes Mellitus
Not yet reported Halozyme Therapeutics 132 participants Est. completion 2011-08 22 sitesOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Status unknown NCT NCT01201278
PK/PD Study of Intranasal Insulin in Type I Diabetes
Not yet reported Hompesch, Marcus, M.D. 20 participants 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01206322
Enhancement of Cerebral Vasoreactivity and Cognition by Intranasal Insulin in Type 2 Diabetes
Not yet reported Beth Israel Deaconess Medical Center 30 participants Est. completion 2013-04 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01213901
Optimizing Insulin Absorption and Insulin Injection Technique in Older Adults
Not yet reported University of British Columbia 20 participants Est. completion 2014-03 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01215955
Study of Insulin Lispro in Participants With Inadequately Controlled Type 2 Diabetes
Not yet reported Eli Lilly and Company 1117 participants Est. completion 2013-01 76 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01216618
Evaluation of the Effect of the InsuPatch Device on Insulin Pharmacokinetics in Clamp Studies
Not yet reported Insuline Medical Ltd. 55 participants Est. completion 2011-06 3 sitesOther conditions: Diabetes Mellitus, Insulin-DependentView official trial listing → -
Completed NCT NCT01235039
A Study Evaluating the Bioequivalence of VIAject®7 Compared to VIAject®25 and Comparing the Pharmacokinetic and Pharmacodynamic Properties of VIAject®7 to Insulin Lispro in Subjects With Type 1 Diabetes Mellitus
Not yet reported, Not yet reported Biodel 43 participants Est. completion 2009-09 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01240785
Metformin Versus Insulin in Gestational Diabetes
Not yet reported Turku University Hospital 221 participants Est. completion 2012-12Other conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT01269034
New Onset Type 1 Diabetes: Role of Exenatide
Not yet reported Albert Einstein College of Medicine 13 participants Est. completion 2017-01-31 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01269047
Use of Exenatide and Pramlintide to Decrease Post-prandial Hyperglycemia
Not yet reported Albert Einstein College of Medicine 37 participants Est. completion 2016-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01283425
Evaluation of the Safety Use of the InsuPatch Device in Daily Life Conditions
Not yet reported Insuline Medical Ltd. 147 participants Est. completion 2012-04 8 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01300260
Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose
Not yet reported Eli Lilly and Company 32 participants Est. completion 2011-08 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT01303042
Efficacy of Insulin Lispro Mix 50/50 Therapy
Not yet reported Aichi Gakuin University 80 participants Est. completion 2014-12 4 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01311076
TAK-329 Glucose Clamp Study
Not yet reported Takeda 37 participants Est. completion 2012-01 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01334151
Pharmacokinetic and Pharmacodynamic Properties of BIOD-105 and BIOD-107 Compared to Humalog® in Subjects With Type 1 Diabetes
Not yet reported Biodel 13 participants Est. completion 2011-08 1 siteOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT01336751
Lantus Versus Humalog Mix as add-on Therapy in Type Diabetes Patients Failing Sulfonylurea and Metformin Combination Treatment
Not yet reported Sanofi 212 participants Est. completion 2002-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01378117
Dipeptidyl Peptidase-4 Inhibitor (Sitagliptin) Therapy in the Inpatients With Type 2 Diabetes
Not yet reported Emory University 90 participants Est. completion 2012-06 2 sitesType 2 diabetes Other conditions: Hospitalization, HyperglycemiaView official trial listing → -
Withdrawn NCT NCT01398670
Immunogenicity Study of Wockhardt's Insulin Lispro/Lispro Mix Basal Bolus Regimen in Type 1 Diabetics
Not yet reported Wockhardt Est. completion 2013-05Other conditions: Type I DiabetesView official trial listing → -
Withdrawn NCT NCT01399255
Comparative Bioequivalence Study of Wockhardt's Insulin Analogue Lispro (Listro™) With Humalog® in Healthy Subjects
Not yet reported Wockhardt Est. completion 2012-06 1 siteOther conditions: Bioequivalence in Healthy SubjectsView official trial listing → -
Withdrawn NCT NCT01400789
Comparative Bioequivalence Study of Wockhardt's Insulin Analogue Listro Mix 50/50® and Humalog Mix50/50® in Healthy Subjects
Not yet reported Wockhardt 1 siteOther conditions: Bioequivalence in Healthy SubjectsView official trial listing → -
Withdrawn NCT NCT01400802
Comparative Bioequivalence Study of Wockhardt's Insulin Analogue Mixture Listro Mix 75/25® and Humalog Mix75/25 ® in Healthy Subjects
Not yet reported Wockhardt Est. completion 2012-06 1 siteOther conditions: Bioequivalence in Healthy SubjectsView official trial listing → -
Status unknown NCT NCT01406496
Best Timing of Insulin Bolus Before Meals of Different Contents
Not yet reported Kaplan Medical Center 24 participants Est. completion 2013-12 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01421147
A Study in Adults With Type 1 Diabetes
Not yet reported Eli Lilly and Company 536 participants Est. completion 2013-04 52 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01436045
Safety and Effectiveness Study of Intranasal Insulin Glulisine on Cognitive and Memory in Mild-Mod AD Patients.
Not yet reported HealthPartners Institute 12 participants Est. completion 2013-06 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01454284
A Study in Participants With Type I Diabetes Mellitus
Not yet reported Eli Lilly and Company 1114 participants Est. completion 2014-02 119 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01468987
A Study in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 1369 participants Est. completion 2013-08 156 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01469559
Safety Study of Intranasal Insulin in Type 1 Diabetes and Diabetic Peripheral Neuropathy
Not yet reported University of Calgary 12 participants Est. completion 2012-07 1 siteOther conditions: Diabetic Peripheral NeuropathyView official trial listing → -
Completed NCT NCT01474538
Safety and Efficacy Study of Insulin Lispro Versus Insulin Aspart in Participants With Type 2 Diabetes on Insulin Pump Therapy
Not yet reported Eli Lilly and Company 122 participants Est. completion 2013-02 12 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01479075
The Effect of Central Insulin on Insulin Sensitivity and Energy Metabolism
Not yet reported German Diabetes Center 30 participants Est. completion 2014-06 1 site Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01481779
A Study in Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 455 participants Est. completion 2014-06 51 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01524705
FLuctuATion Reduction With inSULin and Glp-1 Added togetheR (FLAT-SUGAR)
Not yet reported University of Washington 102 participants Est. completion 2014-07 12 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01526733
Randomized, Double Blind, 2 Way Crossover Study of CSII With, Versus Without, Pretreatment With Human Hyaluronidase
Not yet reported Halozyme Therapeutics 25 participants Est. completion 2013-09 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01531855
Post-exercise Insulin Reductions in Type 1 Diabetes
Not yet reported Northumbria University 13 participants Est. completion 2012-08 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01547169
Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 21 Days
Not yet reported University of Washington 60 participants Est. completion 2012-12 1 siteOther conditions: Alzheimer's Disease, Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT01561378
Cardiac Surgery Neuroprotection Study in Elders
Not yet reported Albert Einstein College of Medicine 22 participants Est. completion 2014-10 1 siteOther conditions: Post-operative Cognitive Decline, Post-operative DeliriumView official trial listing → -
Completed NCT NCT01595646
Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 120 Days (SL120)
Not yet reported Wake Forest University Health Sciences 37 participants Est. completion 2015-03-12 2 sitesOther conditions: Alzheimer's Disease, Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT01613807
Humalog® Mix50/50(tm) as a Treatment for Gestational Diabetes
Not yet reported Sansum Diabetes Research Institute 40 participants Est. completion 2010-10 Stand-aloneOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT01621178
A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD)
Not yet reported Eli Lilly and Company 577 participants Est. completion 2016-12 89 sitesType 2 diabetesChronic kidney diseaseView official trial listing → -
Completed NCT NCT01621776
Effect of Apidra Compared to Humalog in Decreasing Post-Prandial Hyperglycemia
Not yet reported University of Florida 107 participants Est. completion 2012-08 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Withdrawn NCT NCT01636596
Efficacy of Pulsatile IV Insulin on Cognition and Amyloid Burden in Patients With Alzheimer's Disease
Not yet reported Louisiana State University Health Sciences Center Shreveport Est. completion 2015-01 1 siteOther conditions: Alzheimer's Disease, Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT01638325
A Study of Insulin Lispro With BioChaperone Excipient in Healthy Participants
Not yet reported Adocia 37 participants Est. completion 2012-09 1 siteOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT01662921
Comparator Trial Using Insulin Glulisine vs. Insulin Lispro for Treatment of Gestational Diabetes
Not yet reported Sansum Diabetes Research Institute 17 participants Est. completion 2015-08-31 1 siteOther conditions: Diabetes During PregnancyView official trial listing → -
Completed NCT NCT01680185
Sensor-Augmented Insulin-Pump Therapy in New-onset Diabetes After Transplantation
Not yet reported Medical University of Vienna 85 participants Est. completion 2018-05 1 siteOther conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT01684943
Selecting Insulin Analogs for Closed-Loop Control Using Multiplex Pharmacokinetic Profiling
Not yet reported Massachusetts General Hospital 33 participants Est. completion 2017-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01686620
A Study Evaluating Safety and Efficacy of BIOD-123 Compared to Insulin Lispro (Humalog®)
Not yet reported Biodel 132 participants Est. completion 2013-06 34 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01755468
Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Pilot Study)
Not yet reported Mount Sinai Hospital, Canada 24 participants Est. completion 2017-10 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT01756105
Efficacy of Metformin in Achieving Glycaemia Goals as Recommended for the Treatment of Gestational Diabetes in Non Obese Women
Not yet reported University Hospital, Strasbourg, France 84 participants Est. completion 2018-06 5 sites Stand-aloneOther conditions: Gestational Diabetes, Metformin, Treatment, Oxidative StressView official trial listing → -
Completed NCT NCT01762059
Outpatient Automated Blood Glucose Control With a Bi-hormonal Bionic Endocrine Pancreas
Not yet reported Massachusetts General Hospital 32 participants Est. completion 2014-06 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01767909
The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)
Not yet reported, Not yet reported University of Southern California 240 participants Est. completion 2018-12-11 25 sitesOther conditions: Amnestic Mild Cognitive Impairment, Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01773473
Comparison of Insulin Mix25 Versus Mix50
Not yet reported Eli Lilly and Company 403 participants Est. completion 2014-08 27 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01776788
Effect of Short-Term Intensive Insulin Sequential Exenatide Therapy in Newly Diagnosed Type 2 Diabetic Patients
Not yet reported The First Affiliated Hospital of Xiamen University 156 participants Est. completion 2015-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01781234
Efficacy Study of Intranasal Insulin to Treat Tobacco Abstinence Syndrome
Not yet reported Ajna Hamidovic 51 participants Est. completion 2016-05 1 site Stand-aloneOther conditions: Tobacco Abstinence SyndromeView official trial listing → -
Completed NCT NCT01792284
A Study of LY2605541 in Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 212 participants Est. completion 2014-04 18 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01792323
Absorption of Insulin Following Subcutaneous Bolus Administration With Different Bolus Durations
Not yet reported Medical University of Graz 20 participants Est. completion 2014-01 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01797601
Insulin Sensitivity of the Human CNS System: fMRI Study With Intranasal Insulin Application
Not yet reported University Hospital Tuebingen 48 participants Est. completion 2014-04 1 siteOther conditions: Obesity, DiabetesView official trial listing → -
Status unknown NCT NCT01802944
Intranasal Insulin: A Novel Treatment for Gulf War Multisymptom Illness
Not yet reported Bronx Veterans Medical Research Foundation, Inc 114 participants Est. completion 2017-12 2 sites Stand-aloneOther conditions: Chronic Multisymptom Illness in Gulf War VeteransView official trial listing → -
Completed NCT NCT01810952
The Management of Glucocorticoid-Induced Hyperglycemia in Hospitalized Patients
Not yet reported Baylor College of Medicine 37 participants Est. completion 2013-09 1 siteOther conditions: Hyperglycemia, Diabetes MellitusView official trial listing → -
Completed NCT NCT01811849
Pharmacokinetic and Injection Site Toleration of BIOD-238 and BIOD-250 Compared to Humalog® in Subjects With Type 1 Diabetes
Not yet reported Biodel 12 participants Est. completion 2012-12Other conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01845831
Sitagliptin Therapy in Hospitalized Patients With Type 2 Diabetes
Not yet reported Emory University 292 participants Est. completion 2016-04 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01848990
CONSISTENT 1: Metabolic and Safety Outcomes of Hylenex Recombinant (Hyaluronidase Human Injection) Preadministered at CSII Infusion Site in Participants With Type 1 Diabetes Mellitus (T1DM)
Not yet reported Halozyme Therapeutics 456 participants Est. completion 2014-09 39 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01871493
A Study of LY2605541 and Insulin Lispro Mixture in Healthy Participants
Not yet reported Eli Lilly and Company 40 participants Est. completion 2013-09 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT01908894
Pharmacokinetic and Pharmacodynamic Properties of BIOD-123 and BIOD-125 Compared to Humalog® in Subjects With Type 1 Diabetes Including Assessments of Injection Site Toleration
Not yet reported Biodel 12 participants Est. completion 2012-03Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01945099
Acceleration of Insulin Action by Hyaluronidase During Closed-Loop Therapy
Not yet reported Yale University 13 participants Est. completion 2016-07 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01969149
Exenatide for Stress Hyperglycemia
Not yet reported, Not yet reported Centre Hospitalier Universitaire de Besancon 110 participants Est. completion 2016-12 1 siteOther conditions: Stress HyperglycemiaView official trial listing → -
Withdrawn NCT NCT01971047
Safety and Efficacy Study of Correcting Hyperglycemia in Patients With Diabetes Having Out-patient Surgery
Not yet reported Emory University Est. completion 2018-09 1 siteType 2 diabetes Other conditions: Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT01974544
Prevention and Treatment Of Diabetes Complications With Gastric Surgery or Intensive Medicines
Not yet reported Pontificia Universidad Catolica de Chile 150 participants Est. completion 2016-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01981031
A Trial to Assess the Efficacy and Safety of BioChaperone Combo and Humalog Mix 25 in Subjects With Type 1 Diabetes
Not yet reported Adocia 21 participants Est. completion 2014-08 1 siteOther conditions: Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02004366
Linagliptin Inpatient Trial
Not yet reported Emory University 295 participants Est. completion 2017-03 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02012465
Validation of Insulin Protocol for Glucocorticoid-induced Hyperglycemia in Diabetic Oncology Patients
Not yet reported Washington University School of Medicine 15 participants Est. completion 2015-05 1 siteType 2 diabetes Other conditions: Lymphoma, HyperglycemiaView official trial listing → -
Completed NCT NCT02028871
Intranasal Insulin for Weight Management During Smoking Cessation
Not yet reported Ajna Hamidovic 26 participants Est. completion 2016-05 2 sitesOther conditions: Tobacco Abstinence SyndromeView official trial listing → -
Completed NCT NCT02029924
A Double-blinded, Randomised, Two -Period Crossover Euglycemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Insulin Lispro and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes
Not yet reported Adocia 37 participants Est. completion 2014-08 1 siteOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT02064166
Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin.
Not yet reported Peter Novak 15 participants Est. completion 2015-09 1 site Stand-aloneOther conditions: Parkinson Disease, Multiple System AtrophyView official trial listing → -
Completed NCT NCT02111083
A Study of 2 Different Formulations of Insulin Lispro in Healthy Participants
Not yet reported Eli Lilly and Company 38 participants Est. completion 2014-08 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02131948
Regulation of Endogenous Glucose Production by Brain Insulin Action
Not yet reported University Health Network, Toronto 8 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: Insulin Resistance, DiabetesView official trial listing → -
Completed NCT NCT02146651
A Double-blinded, Randomised, Four-period Crossover Euglycemic Clamp Trial Investigating the Dose-response and Dose-exposure Relationship of BioChaperone Insulin Lispro in Three Different Doses in Subjects With Type 1 Diabetes
Not yet reported Adocia 38 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT02152384
A Study to Compare and Measure the Effects of Insulin Peglispro (LY2605541) and Glargine on Meal Time Insulin Requirements
Not yet reported Eli Lilly and Company 28 participants Est. completion 2014-12 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02154477
Effect of Intranasal Insulin on LH Concentrations in Man
Not yet reported, Not yet reported Texas Tech University Health Sciences Center 14 participants Est. completion 2017-12 1 siteOther conditions: Hypogonadotropic HypogonadismView official trial listing → -
Completed NCT NCT02155023
Feasibility Study to Determine the Optimal Calibration Method for Glucose Sensors
Not yet reported Medical University of Graz 8 participants Est. completion 2015-01 1 siteOther conditions: DiabetesView official trial listing → -
Status unknown NCT NCT02164032
The Role of IntraNasal Insulin in Regulating HepaTic Lipid COntent in HUMANS
Not yet reported Medical University of Vienna 20 participants Est. completion 2016-12 1 siteOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT02165566
Humalog or Humulin for Intensive Insulin Therapy in Intensive Care Unit
Not yet reported University of Roma La Sapienza 28 participants Est. completion 2014-05 1 siteOther conditions: HyperglycemiaView official trial listing → -
Terminated NCT NCT02189395
Comparison of Neutral Protamine Hagedorn (NPH) and Lantus Based Insulin Regimen in the Management of Hypoglycemia in the Hospitalized Patients in Noncritical Care Setting
Not yet reported Riverside University Health System Medical Center 52 participants Est. completion 2017-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02192424
Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Main Trial)
Not yet reported Mount Sinai Hospital, Canada 109 participants Est. completion 2020-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02194595
Preserving Beta-cell Function in Type 2 Diabetes With Exenatide and Insulin (PREVAIL)
Not yet reported Mount Sinai Hospital, Canada 105 participants Est. completion 2022-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02197520
A Study To Compare the Effects of Insulin Peglispro and Glargine on Insulin Sensitivity and Meal Time Insulin Requirements in Type 2 Diabetics
Not yet reported Eli Lilly and Company 24 participants Est. completion 2015-06 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02206568
Pharmacokinetics of Ultra-Rapid-Acting Insulin Lispro (URAL) in Type 1 Diabetes Mellitus
Not yet reported Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc. Est. completion 2014-09 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02212951
Comparison of Postprandial Glucose Control Associated With BIOD-531 vs. Humalog Mix 75/25 vs. Humulin R U-500
Not yet reported, Not yet reported Biodel 12 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02213146
A Double-blinded, Randomised, Three-period Crossover Euglycaemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Human Insulin, Human Insulin (Huminsulin® Normal) and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes
Not yet reported, Not yet reported Adocia 38 participants Est. completion 2015-06 1 site Stand-aloneOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT02221323
A Trial to Compare the PK and PD of Insulin Lispro Administered Into Different Tissues in Subjects With Diabetes Mellitus Type 1
Not yet reported Profil Institut für Stoffwechselforschung GmbH 18 participants Est. completion 2014-11 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02227862
Non-inferiority Study to Compare the Efficacy and Safety of Mylan's Insulin Glargine With Lantus® in Type 1 Diabetes Mellitus Patients (INSTRIDE 1)
Not yet reported Mylan Inc. 558 participants Est. completion 2016-07 162 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02229227
Safety and Efficacy of Albiglutide + Insulin Glargine Versus Insulin Lispro + Insulin Glargine Subjects With Type 2 Diabetes Mellitus
Not yet reported GlaxoSmithKline 814 participants Est. completion 2017-07-24 157 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02248454
Insulin Bolus Required for High Fat Foods in Type 1 Diabetes
Not yet reported Joslin Diabetes Center 10 participants Est. completion 2015-04Other conditions: Type 1 DiabetesView official trial listing → -
Withdrawn NCT NCT02250794
Metformin and Sitagliptin Therapy for Adult Patients With Type 2 Diabetes Admitted to the General Medical Unit
Not yet reported Rush University Medical Center Est. completion 2015-05Type 2 diabetesView official trial listing → -
Completed NCT NCT02273180
Comparison of SAR342434 to Humalog as the Rapid Acting Insulin in Adult Patients With Type 1 Diabetes Mellitus Also Using Insulin Glargine
Not yet reported Sanofi 507 participants Est. completion 2016-07 89 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02273258
A Study to Compare Pharmacokinetics and Pharmacodynamics of SAR342434 to Insulin Lispro in Subjects With Type 1 Diabetes
Not yet reported Sanofi 30 participants Est. completion 2013-07 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02276859
Normal Versus Dual Wave Insulin Bolus for High-protein Food
Not yet reported Medical University of Warsaw 70 participants Est. completion 2015-09 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02293551
A Study of Lispro Formulations in Healthy Participants
Not yet reported Eli Lilly and Company 54 participants Est. completion 2015-09 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02294474
Comparison of SAR342434 to Humalog as the Rapid Acting Insulin in Adult Patients With Type 2 Diabetes Mellitus Also Using Insulin Glargine
Not yet reported Sanofi 505 participants Est. completion 2016-02 103 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02317575
A Study of LY900014 Formulations in Healthy Participants
Not yet reported Eli Lilly and Company 29 participants Est. completion 2015-09 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02324309
BIOD-531 vs. Humalog Mix 75/25 vs. Humulin R U-500 Post-Meal Glucose Control in Patients With Severe Insulin Resistance
Not yet reported, Not yet reported Biodel 12 participants 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02344992
Blood Glucose Control With BioChaperone Insulin Lispro Compared to Insulin Lispro (Humalog®) After Ingestion of a Standardized Meal
Not yet reported Adocia 38 participants Est. completion 2015-06 1 siteOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT02415556
Memory Aid by Intranasal Insulin in Diabetes (MemAID)
Not yet reported Beth Israel Deaconess Medical Center 289 participants Est. completion 2020-05-31 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02416765
Closed-loop Control of Postprandial Glucose Levels in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 15 participants Est. completion 2015-10 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02417090
Late Metabolic Effects of Metformin Therapy in Gestational Diabetes
Turku University Hospital 173 participants Est. completion 2019-12-01Other conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT02432976
Impact of Perioperative Exenatide Infusion on Quality of Life in Cardiac Surgery Patients
Not yet reported, Not yet reported Centre Hospitalier Universitaire de Besancon 64 participants Est. completion 2017-01 1 siteOther conditions: Quality of LifeView official trial listing → -
Completed NCT NCT02443402
Sitagliptin in Non-Diabetic Patients Undergoing Cardiac Surgery
Not yet reported Emory University 68 participants Est. completion 2016-12 4 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT02443714
Pharmacokinetic and Pharmacodynamic Profile of Insulin Lispro Using Needle-Free Jet Injection Technology
Not yet reported Chongqing Medical University 18 participants Est. completion 2015-09 1 siteOther conditions: HealthyView official trial listing → -
Suspended NCT NCT02446028
A Study Evaluating Safety and Efficacy of BIOD 531 Compared to Humalog® Mix 75/25 in Subjects With Type 2 Diabetes
Not yet reported Biodel 13 participants Est. completion 2016-05 7 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02451917
Glargine Versus NPH in Patients With Chronic Kidney Disease
Not yet reported University of Sao Paulo General Hospital 34 participants Est. completion 2016-08 1 site Stand-aloneType 2 diabetesChronic kidney diseaseView official trial listing → -
Completed NCT NCT02468999
Influence of Central Nervous Insulin Action on Insulin Sensitivity of Peripheral Organs in Lean Versus Overweight Humans
Not yet reported University Hospital Tuebingen 21 participants Est. completion 2015-12 1 siteOther conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT02470637
Single Dose Clamp Study to Evaluate Concentration-time Profile and Metabolic Activity of 3 Dose Levels of Afrezza and 3 Dose Levels of Insulin Lispro in Patients With Type 1 Diabetes Mellitus
Not yet reported Mannkind Corporation 30 participants Est. completion 2015-09 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Withdrawn NCT NCT02488616
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 5 Days in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal Est. completion 2018-11 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Withdrawn NCT NCT02490098
Closed-loop Control of Postprandial Glucose Levels in Children and Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal Est. completion 2018-07 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02500979
Effect of a Fixed Pramlintide: Insulin Dose Ratio on Postprandial Glucose in Type 1 Diabetes Mellitus
Not yet reported AstraZeneca 34 participants Est. completion 2016-08-05 3 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Terminated NCT NCT02503501
Intranasal Glulisine in Amnestic Mild Cognitive Impairment and Probable Mild Alzheimer's Disease
Not yet reported HealthPartners Institute 49 participants Est. completion 2019-02-15 2 sitesOther conditions: Mild Cognitive Impairment, Alzheimer's Disease (AD)View official trial listing → -
Completed NCT NCT02509429
Comparison of an Artificial Pancreas Versus Threshold Low Glucose Suspend in Type 1 Diabetic Children
Not yet reported University Hospital, Montpellier 24 participants Est. completion 2016-12 4 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02514850
A Trial to Compare the Pharmacodynamic and Pharmacokinetic Properties of Biochaperone® Combo With Humalog® Mix25 and With Simultaneous Injections of Humalog® and Lantus® in Subjects With Type 2 Diabetes
Not yet reported Adocia 24 participants Est. completion 2015-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02514954
Postprandial Blood Glucose Control With BioChaperone® Combo and Insulin Lispro (Humalog®) Mix 25 in People With Type 1 Diabetes Mellitus
Not yet reported Adocia 28 participants Est. completion 2015-11 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Withdrawn NCT NCT02518022
How to be Safe With Alcoholic Drinks in Diabetes
Not yet reported Kinderkrankenhaus auf der Bult Est. completion 2016-06 1 siteOther conditions: Type 1 Diabetes Mellitus, HypoglycemiaView official trial listing → -
Completed NCT NCT02518945
Dapagliflozin As Additional Treatment To Liraglutide And Insulin In Patients With Type 1 Diabetes
Not yet reported University at Buffalo 26 participants Est. completion 2016-04 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02525744
A Study of a New LY900014 Formulation in Healthy Participants
Not yet reported Eli Lilly and Company 24 participants Est. completion 2015-10 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02526810
Comparison of Glycaemic Fluctuation and Oxidative Stress Between Two Short-term Therapies for Type 2 Diabetes
Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 70 participants Est. completion 2016-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02528396
To Investigate the Efficacy and Safety of Individualized Doses of BioChaperone Insulin Lispro in Comparison to Humalog® U-100 in Patients With Type 1 Diabetes Mellitus
Not yet reported Adocia 36 participants Est. completion 2015-12 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02529293
A Clinical Trial Investigating the Intra-subject Variability of Pharmacokinetics and Glucodynamics of BioChaperone Insulin Lispro U-100 Product and U-200 Product in Healthy Volunteers
Not yet reported Adocia 26 participants Est. completion 2015-11 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02556840
Impact on Birth Weight of Two Therapeutic Strategies (Insulin Therapy From the Beginning of Pregnancy vs. Insulin Therapy Initiated According to Fetal Growth Evaluated by Ultrasonography Measurements) in Pregnant Women With Monogenic Diabetes
Not yet reported Assistance Publique - Hôpitaux de Paris 46 participants Est. completion 2020-12-09 1 site Stand-aloneOther conditions: Maturity-Onset Diabetes of the YoungView official trial listing → -
Completed NCT NCT02556918
Sitagliptin for Hyperglycemia in Patients With T2DM Undergoing Cardiac Surgery
Not yet reported Emory University 202 participants Est. completion 2018-11-06 3 sitesOther conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT02562313
A Trial Investigating the Continuous Subcutaneous Insulin Infusion of a Liquid Formulation of BioChaperone Insulin Lispro in Comparison to Humalog®
Not yet reported Adocia 80 participants Est. completion 2016-11 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02562326
A Trial to Investigate the Efficacy, Pharmacokinetics, Safety and Tolerability of BioChaperone Insulin Lispro in Comparison to Humalog® U-100 in Patients With Type 2 Diabetes Mellitus
Not yet reported Adocia 51 participants Est. completion 2016-01 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02603510
Assessment of the Safety of SAR342434 and Humalog® When Administered as Continuous Subcutaneous Insulin Infusion
Not yet reported Sanofi 27 participants Est. completion 2016-04 2 sites Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Withdrawn NCT NCT02623452
A Study of a New Type of Insulin in Participants With Type 1 Diabetes on Insulin Injection Therapy
Not yet reported Eli Lilly and Company Est. completion 2018-04Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Withdrawn NCT NCT02623465
A Study of a New Type of Insulin in Participants With Type 2 Diabetes on Insulin Injection Therapy
Not yet reported Eli Lilly and Company Est. completion 2018-04Type 2 diabetesView official trial listing → -
Withdrawn NCT NCT02623478
A Study of a Novel Insulin Lispro Formulation in Participants With Type 1 Diabetes Mellitus Using Insulin Pumps
Not yet reported Eli Lilly and Company Est. completion 2018-04Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02626936
Safety of Overestimation of a Meal Insulin Bolus in the Context of Dual-hormone Closed-loop Operation
Not yet reported Institut de Recherches Cliniques de Montreal 10 participants Est. completion 2016-06 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02636361
A Study of Various Formulations of LY900014 in Healthy Participants
Not yet reported Eli Lilly and Company 26 participants Est. completion 2016-02 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02660502
An Euglycemic Clamp Trial to Evaluate Pharmacokinetics of Single Doses of BioChaperone Insulin Lispro in Healthy Japanese Subjects
Not yet reported Adocia 15 participants Est. completion 2016-05 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02666430
Extension Study to Assess Safety and Efficacy of Mylan's Insulin Glargine and Lantus® in Type 1 Diabetes Mellitus (T1DM) Patients
Not yet reported Mylan Inc. 127 participants Est. completion 2017-07 81 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT02685449
Insulin Requirement for Pure-protein Meal in Children With Type 1 Diabetes on Insulin Pumps.
Not yet reported Medical University of Warsaw 70 participants Est. completion 2018-08 1 siteOther conditions: Diabetes type1View official trial listing → -
Completed NCT NCT02688933
A Study Comparing the Efficacy and Safety of the Morning Injection of Toujeo Versus Lantus in Patients With Type 1 Diabetes Mellitus
Not yet reported Sanofi 638 participants Est. completion 2017-06-19 100 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02690883
Effect of Exenatide on 24h-UAER in Patients With Diabetic Nephropathy
Not yet reported Nanfang Hospital, Southern Medical University 92 participants Est. completion 2019-12-30Other conditions: Diabetic NephropathiesView official trial listing → -
Terminated NCT NCT02701257
The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic Pancreas
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2018-05 1 siteOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT02703324
A Study of LY900014 Formulation in Participants With Type 1 Diabetes Mellitus Using Insulin Pumps
Not yet reported Eli Lilly and Company 30 participants Est. completion 2016-08 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02703337
A Study of LY900014 in Participants With Type 2 Diabetes on Insulin Injection Therapy
Not yet reported Eli Lilly and Company 30 participants Est. completion 2016-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02703350
A Study of LY900014 in Participants With Type 1 Diabetes on Insulin Injection Therapy
Not yet reported Eli Lilly and Company 30 participants Est. completion 2016-07 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02713841
Pharmacologic Response and Safety of Inhaled Insulin in Type 1 Diabetes
Not yet reported, Not yet reported Dance Biopharm Inc. 12 participants Est. completion 2013-07Other conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02716610
Dose-Response and Variability of Inhaled Insulin in Type 2 Diabetes
Not yet reported, Not yet reported Dance Biopharm Inc. 24 participants Est. completion 2014-01Type 2 diabetesView official trial listing → -
Status unknown NCT NCT02729064
Intraoperative Nasal Insulin Effect on Plasma and CSF Insulin Concentration and Blood Glucose
Not yet reported Hiroaki Sato, MD., PhD. 141 participants Est. completion 2021-09 1 site Stand-aloneOther conditions: Ischemic Heart Disease, Aortic AneurysmView official trial listing → -
Completed NCT NCT02739906
A Trial to Investigate Post Prandial Blood Glucose Control With Fast-acting Human Insulin HinsBet® Compared to Insulin Lispro (Humalog®) and Regular Human Insulin (Huminsulin® Normal) After Ingestion of a Standardized Meal in Subjects With T1DM
Not yet reported, Not yet reported Adocia 36 participants Est. completion 2016-08 2 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02741687
Sitagliptin in Non-Diabetic Patients Undergoing General Surgery
Not yet reported Emory University 80 participants Est. completion 2017-04 2 sitesOther conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT02752087
A Study to Compare the Effects of a Test and Reference Formulation of LY900014 in Healthy Participants
Not yet reported Eli Lilly and Company 24 participants Est. completion 2016-05 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02758691
fMRI Study of Effects of Nasal Insulin on Memory
Not yet reported Virginia Polytechnic Institute and State University 45 participants Est. completion 2017-05-10 Stand-aloneOther conditions: Human Memory, Intranasal InsulinView official trial listing → -
Completed NCT NCT02770521
A Study of Treprostinil and a New Formulation of LY900014 in Healthy Japanese Participants
Not yet reported Eli Lilly and Company 23 participants Est. completion 2016-07 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02794155
Study of HDV Insulin Versus Insulin in Type 1 Diabetes Subjects (ISLE-1)
Not yet reported Diasome Pharmaceuticals 157 participants Est. completion 2018-06-15 21 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02798250
Safety of Overestimation of a Meal Insulin Bolus in the Context of Dual-hormone Closed-loop Operation - Part 2
Not yet reported Institut de Recherches Cliniques de Montreal 11 participants Est. completion 2017-03 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02810392
Intranasal Insulin and Post-stroke Cognition: A Pilot Study
Not yet reported Wake Forest University Health Sciences 20 participants Est. completion 2020-03-04 1 siteCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT02811484
Efficacy of Exenatide-LAR and Dapagliflozin in Overweight/Obese, Insulin Treated Patients With Type 2 Diabetes
Not yet reported Weill Medical College of Cornell University Est. completion 2018-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02814123
Effect of Basal-Bolus Closed-Loop Co-Administration of Insulin and Pramlintide on Improving the Glycemic Control in Type 1 Diabetes
Not yet reported McGill University 28 participants Est. completion 2018-07-08 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02846831
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 12 Days in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 36 participants Est. completion 2020-01-27 2 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Withdrawn NCT NCT02846857
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 15 Weeks in Adolescents and Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de MontrealOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02855307
Closed-loop Control of Glucose Levels (Artificial Pancreas) During Postprandial Exercise in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 37 participants Est. completion 2018-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02870361
Influence of Central Nervous Insulin Sensitivity on Insulin Secretion
Not yet reported University Hospital Tuebingen 15 participants Est. completion 2018-04 1 siteOther conditions: Insulin SecretionView official trial listing → -
Status unknown NCT NCT02871089
Closed Loop From Onset in Type 1 Diabetes
Not yet reported University of Cambridge 96 participants Est. completion 2024-07-31 7 sitesOther conditions: Diabetes Mellitus, Type 1 DiabetesView official trial listing → -
Completed NCT NCT02915250
A Trial to Compare Post Prandial Blood Glucose Control of BioChaperone® Combo With Humalog® Mix25 and With Simultaneous Injections of Humalog® and Lantus® in Subjects With Type 2 Diabetes
Not yet reported Adocia 36 participants Est. completion 2017-06 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02933645
Effects of Intranasal Insulin Administration on Tissue Specific Insulin Sensitivity
Not yet reported Turku University Hospital 10 participants Est. completion 2016-12 1 siteOther conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT02942654
A Study of LY900014 Formulation in Healthy Participants
Not yet reported Eli Lilly and Company 32 participants Est. completion 2016-12 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02962921
Insulin Effects on Cardiac Function in Patients With Diabetes Mellitus
Not yet reported Rambam Health Care Campus 6 participants Est. completion 2004-11 1 siteOther conditions: Diabetes Mellitus, Ventricular DysfunctionView official trial listing → -
Completed NCT NCT02971228
Feasibility Trial Testing the Bionic Pancreas With ZP4207
Not yet reported Zealand Pharma 13 participants Est. completion 2017-06-07 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02988401
Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis
Not yet reported, Not yet reported Johns Hopkins University 105 participants Est. completion 2021-12-17 1 site Stand-aloneOther conditions: Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Secondary Progressive, Multiple Sclerosis, Primary ProgressiveView official trial listing → -
Completed NCT NCT03056456
A Study of LY900014 Administered in Participants With Type 1 Diabetes Using an Insulin Pump
Not yet reported Eli Lilly and Company 24 participants Est. completion 2017-06-19 2 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Terminated NCT NCT03081117
Intranasal Insulin for the Treatment of HAND
Not yet reported, Not yet reported Johns Hopkins University 21 participants Est. completion 2020-10-16 1 site Stand-aloneOther conditions: HIV Dementia, HIV-Associated Cognitive Motor ComplexView official trial listing → -
Completed NCT NCT03096392
Comparison of Hepatic Directed Vesicle (HDV)-Insulin Lispro Versus Insulin Lispro to Further Improve Glycemic Control
Not yet reported Diasome Pharmaceuticals 46 participants Est. completion 2018-03-18 5 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03102476
Environmental Effects Type 1 Diabetes Mellitus
Not yet reported University of Hull 10 participants Est. completion 2018-02-02 1 siteOther conditions: Type1diabetesView official trial listing → -
Completed NCT NCT03141827
The Effect of Intranasal Insulin on Hepatic and Intestinal Triglyceride-rich Lipoprotein Production
Not yet reported, Not yet reported University Health Network, Toronto 9 participants Est. completion 2017-04-26 1 siteOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT03156361
21 Day Comparison of Continuous Insulin Infusion Using HDV Insulin to Standard Insulin in Type 1 Diabetes Mellitus
Not yet reported Diasome Pharmaceuticals 24 participants Est. completion 2018-03-15 1 siteOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03166124
A Study of LY900014 in Elderly and Younger Adult Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 80 participants Est. completion 2017-11-18 2 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03170544
Single Ascending Dose Study of MK-1092 in Healthy Participants and in Participants With Type 1 and Type 2 Diabetes Mellitus (MK-1092-001)
Not yet reported Merck Sharp & Dohme LLC 69 participants Est. completion 2018-11-08 1 site Stand-aloneType 2 diabetes Other conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03179332
A Trial to Evaluate the Pharmacokinetic and Pharmacodynamic Properties of BioChaperone® Insulin Lispro, Fiasp® and NovoRapid® Delivered by an Insulin Pump
Not yet reported Adocia 43 participants Est. completion 2017-09-27 1 siteOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03180710
A Trial to Investigate the Dose-linearity of BioChaperone® Combo 75/25 and the Safety at Three Different Doses in Subjects With Type 2 Diabetes
Not yet reported Adocia 32 participants Est. completion 2017-12-21 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03182322
PINIT Study: Primary Intranasal Insulin Trial
Not yet reported Technical University of Munich 38 participants Est. completion 2021-06-07 2 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03214367
A Study of LY900014 in Participants With Type 1 Diabetes
Not yet reported Eli Lilly and Company 1392 participants Est. completion 2019-08-22 172 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03214380
A Study of LY900014 Compared to Insulin Lispro in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 933 participants Est. completion 2019-03-13 141 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT03229850
Dynamics of Insulin Absorption in Subclinical Lipohypertrophy Using the Euglycemic Clamp Technique
Not yet reported Graydon Meneilly Est. completion 2025-04-22 1 siteOther conditions: Diabetes Mellitus, LipohypertrophyView official trial listing → -
Completed NCT NCT03232983
A Study of LY900014 Formulation at Different Injection Sites in Healthy Participants
Not yet reported Eli Lilly and Company 28 participants Est. completion 2017-11-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03234491
Improving Post-Prandial Blood Glucose Control With Afrezza During Closed-Loop Therapy
Not yet reported Yale University 15 participants Est. completion 2019-07-22 1 siteOther conditions: Post-Prandial Hyperglycemia, Post-Prandial HypoglycemiaView official trial listing → -
Withdrawn NCT NCT03248271
Effects of Insulin on Hypotension and Sarcopenia
Kenneth Madden Est. completion 2023-01-10 1 siteOther conditions: Diabetes, Sarcopenia, Hypotension, OrthostaticView official trial listing → -
Terminated NCT NCT03260868
Evaluation of Virtual Versus Traditional Study Conducted in a Group Pilot Study in Adult Patients With Type 1 Diabetes Mellitus (eStudy)
Not yet reported Sanofi 15 participants Est. completion 2018-11-22 6 sites Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Terminated NCT NCT03262116
Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas
Not yet reported, Not yet reported Massachusetts General Hospital 20 participants Est. completion 2019-07-23 1 site Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Terminated NCT NCT03277222
Intranasal Treatment of HIV-associated Neurocognitive Disorders
Not yet reported University of Calgary 4 participants Est. completion 2019-04-21 1 siteOther conditions: HIV Associated Neurocognitive Disorder (HAND)View official trial listing → -
Completed NCT NCT03286751
A Comparative Study of LY900014 to Insulin Lispro (Humalog) in Healthy Participants
Not yet reported Eli Lilly and Company 42 participants Est. completion 2018-02-06 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03305822
A Study of LY900014 in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 38 participants Est. completion 2017-12-14 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT03307512
PK and PD Profile of Dance 501 in Healthy, Non-diabetic Subjects With Mild to Moderate Asthma or COPD
Not yet reported Dance Biopharm Inc. 40 participants Est. completion 2019-08-30 1 siteOther conditions: Safety and TolerabilityView official trial listing → -
Status unknown NCT NCT03320031
A Study of Adding Linagliptin to Control Glycemic Variability and HbA1c in Peritoneal Dialysis Patients With Type 2 Diabetes(PDPD) With Premixed Insulin Therapy
Not yet reported Yanbing Li 232 participants Est. completion 2019-12 1 site Stand-aloneType 2 diabetes Other conditions: Peritoneal DialysisView official trial listing → -
Status unknown NCT NCT03324867
The Effect of Intranasal Insulin Administration on Cognitive Function After Cardiac Surgery.
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 316 participants Est. completion 2023-04 Stand-aloneOther conditions: Cognitive Decline, Heart Diseases, DeliriumView official trial listing → -
Completed NCT NCT03328845
Impact on the Oxidative Stress of the Different Analogues of Insulin in People With Type 1 Diabetes. (Ineox Study)
Not yet reported Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud 300 participants Est. completion 2021-11-20 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03334448
A Study to Compare 2 Formulations of LY900014 in Healthy Participants
Not yet reported Eli Lilly and Company 49 participants Est. completion 2018-03-15 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT03338023
A Study of LY2963016 Compared to Lantus® in Adult Chinese Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 272 participants Est. completion 2020-03-05 20 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT03341299
A Comparative Study of LY900014 With Insulin Lispro (Humalog) in Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 36 participants Est. completion 2018-04-03 2 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03341312
A Comparative Study of LY900014 With Insulin Lispro (Humalog) in Participants With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Eli Lilly and Company 36 participants Est. completion 2018-03-31 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03350984
Insulin Schemes for Type 2 Diabetes Control
Not yet reported Universidad de Guanajuato 75 participants Est. completion 2018-07-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03367390
A Study of an Automated Insulin Delivery System in Participants With Type 1 Diabetes Mellitus (T1DM)
Not yet reported Eli Lilly and Company 30 participants Est. completion 2018-02-09 1 siteOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03368807
Assessment of Mealtime Bolus Insulin Behavior
Eli Lilly and Company 79 participants Est. completion 2018-07-23 6 sitesType 2 diabetes Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03383822
Regulation of Endogenous Glucose Production by Brain Insulin Action in Insulin Resistance
Not yet reported, Not yet reported University Health Network, Toronto 7 participants Est. completion 2017-12-01 1 site Stand-aloneOther conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT03407118
A Study of LY900014 in Japanese Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 31 participants Est. completion 2018-07-12 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT03415061
Effect of Intranasal Insulin on POCD and POD
Not yet reported Hiroaki Sato, MD., PhD. 494 participants Est. completion 2024-11-30 1 site Stand-aloneOther conditions: Delirium, Heart DiseasesView official trial listing → -
Completed NCT NCT03433677
A Study of LY900014 and Insulin Lispro With an External Continuous Subcutaneous Insulin Infusion System in Adult Participants With Type 1 Diabetes
Not yet reported Eli Lilly and Company 49 participants Est. completion 2018-09-04 5 sites Stand-aloneOther conditions: Diabetes Type 1View official trial listing → -
Completed NCT NCT03449433
A Meal Test Study of LY900014 in Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 80 participants Est. completion 2018-08-14 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03465878
A Study of LY900014 in Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 56 participants Est. completion 2019-11-14 2 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03495908
Regular Insulin vs Rapid Insulin Delivered by V-Go
Not yet reported East Coast Institute for Research 136 participants Est. completion 2019-08-12 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03507829
Insulin Therapy for the Prevention of New Onset Diabetes After Transplantation Prospective Study in Non-Diabetic De Novo Kidney Transplant Recipients
Not yet reported Medical University of Vienna 263 participants Est. completion 2018-05-22Other conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT03509324
Effectiveness of Glucose Control, β Cell Function in Response to Short-term Insulin Pump Therapy in Type 2 Diabetes
Not yet reported Sun Yat-sen University 67 participants Est. completion 2015-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03512236
A Trial to Investigate Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BioChaperone® Pramlintide Insulin in Patients With Type 1 Diabetes Mellitus
Not yet reported Adocia 24 participants Est. completion 2019-02-14 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Terminated NCT NCT03547427
Glucagon Counterregulation in Type 1 Diabetes
Not yet reported University of Virginia 13 participants Est. completion 2019-03-11 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT03563794
Efficacy and Safety of Vildagliptin Added to Continuous Subcutaneous Insulin Infusion in Uncontrolled Type 2 Diabetes
Not yet reported The First Affiliated Hospital of Xiamen University 400 participants Est. completion 2019-12-10 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03565666
The Insulin-Only Bionic Pancreas Bridging Study
Not yet reported, Not yet reported Massachusetts General Hospital 36 participants Est. completion 2018-11-19 3 sites Stand-aloneOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03604575
A Study to Compare Pharmacokinetics and Pharmacodynamics of Insulin Lispro to Humalog® in Healthy Subjects
Not yet reported Geropharm 28 participants Est. completion 2016-12-26 1 siteOther conditions: Clamp StudyView official trial listing → -
Completed NCT NCT03606018
A Study to Compare Pharmacokinetics and Pharmacodynamics of Insulin Lispro Mix 25 to Humalog® Mix 25 in Healthy Subjects
Not yet reported Geropharm 48 participants Est. completion 2017-07-13 2 sitesOther conditions: Clamp StudyView official trial listing → -
Completed NCT NCT03616977
Study to Compare 2 Formulations of LY900014 in Healthy Participants
Not yet reported Eli Lilly and Company 69 participants Est. completion 2018-10-19 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT03632681
Effect of Intranasal Insulin on Cognitive Processes and Appetite
Not yet reported University of Birmingham 64 participants Est. completion 2019-04-01 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03637075
Raclopride-PET/MRT
Not yet reported University Hospital Tuebingen 24 participants Est. completion 2023-12-31 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT03660553
Simplified Insulin Regimen for the Elderly
Not yet reported University of Miami 7 participants Est. completion 2022-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03662334
A Study of Continuous Subcutaneous Insulin Infusion (CSII) Pump Function in Subjects With Type 1 Diabetes With Recombinant Human Hyaluronidase (rHuPH20)
Not yet reported Halozyme Therapeutics 14 participants Est. completion 2014-02-27 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03670641
Remission Through Early Monitored Insulin Therapy - Duration Month
Not yet reported Sandra Sobel 10 participants Est. completion 2020-07-31 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03682640
Azithromycin Insulin Diet Intervention Trial in Type 1 Diabetes
Not yet reported Uppsala University 60 participants Est. completion 2021-12-31 1 siteOther conditions: Diabetes Mellitus, Type 1, Diabetes Mellitus, Metabolic Disease, Glucose Metabolism Disorders, Endocrine System Diseases, Juvenile Diabetes, Insulin Dependent Diabetes, Type 1 Diabetes Mellitus, Inflammation, Diet ModificationView official trial listing → -
Completed NCT NCT03740919
A Study Comparing LY900014 to Insulin Lispro (Humalog) in Children and Adolescents With Type 1 Diabetes
Not yet reported Eli Lilly and Company 751 participants Est. completion 2021-07-02 111 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Active, not recruiting NCT NCT03741478
Intranasal Insulin and Olanzapine Study in Healthy Volunteers
Not yet reported Centre for Addiction and Mental Health 64 participants Est. completion 2026-07-30 2 sites Stand-aloneOther conditions: Healthy ControlsView official trial listing → -
Completed NCT NCT03743285
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus (T1D)
Not yet reported Eli Lilly and Company 10 participants Est. completion 2019-01-28 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03760640
A Study of LY900014 in a Medtronic Pump
Not yet reported Eli Lilly and Company 42 participants Est. completion 2019-10-07 2 sitesOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03830281
A Study Comparing LY900014 to Insulin Lispro (Humalog) in Adults With Type 1 Diabetes Using Insulin Pump Therapy
Not yet reported Eli Lilly and Company 471 participants Est. completion 2020-01-06 83 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03848767
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus During Meal Challenges
Not yet reported Eli Lilly and Company 10 participants Est. completion 2019-04-01 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03849612
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 10 participants Est. completion 2019-03-27 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03890003
A Study of an Automated Insulin Delivery System in Adult Participants With Type 1 Diabetes
Not yet reported Eli Lilly and Company 10 participants Est. completion 2019-05-06 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03903016
A Bioequivalence Study Comparing Two Different Strengths Formulations of Insulin Lispro in Patients With Type 1 Diabetes
Not yet reported Sanofi 90 participants Est. completion 2019-08-19 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT03915613
Brain Insulin Resistance in Mood Disorders
Not yet reported, Not yet reported University Health Network, Toronto 150 participants Est. completion 2024-10-05 1 site Stand-aloneOther conditions: Major Depressive Disorder, Bipolar Disorder, Anhedonia, Intranasal InsulinView official trial listing → -
Completed NCT NCT03916640
A Trial to Assess a Co-formulation of an Insulin Analog and Pramlintide in Subjects With Type 1 Diabetes Mellitus
Not yet reported Adocia 24 participants Est. completion 2019-03-01 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03929419
"Effect of Central Insulin Administration on Whole-body Insulin Sensitivity in Women"
Not yet reported University Hospital Tuebingen 29 participants Est. completion 2021-04-30 1 siteOther conditions: Insulin SensitivityView official trial listing → -
Completed NCT NCT03938740
Comparison of Different Insulin Dosing Algorithms Using Hepatic Directed Vesicle-Insulin Lispro and Insulin Degludec
Not yet reported Diasome Pharmaceuticals 61 participants Est. completion 2020-03-18 7 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03943537
Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders
Not yet reported Mclean Hospital 87 participants Est. completion 2024-02-23 1 site Stand-aloneOther conditions: Psychosis, Schizophrenia, Schizo Affective Disorder, Bipolar I DisorderView official trial listing → -
Completed NCT NCT03952130
A Study of LY900014 Compared to Insulin Lispro (Humalog) in Adults With Type 1 Diabetes
Not yet reported Eli Lilly and Company 354 participants Est. completion 2022-01-10 30 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03952143
A Study of LY900014 Compared to Insulin Lispro (Humalog) in Adults With Type 2 Diabetes
Not yet reported Eli Lilly and Company 628 participants Est. completion 2021-01-20 41 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04019821
Super-Bolus: Effects on Postprandial Glycemia After High Glycemic Index Meal
Not yet reported Medical University of Warsaw 72 participants Est. completion 2023-04-01 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT04023344
Efficacy and Safety of Insulin Lispro Biphasic 25 Compared to Humalog® Mix 25 in Type 2 Diabetes Mellitus Patients
Not yet reported Geropharm 210 participants Est. completion 2019-04-18 18 sitesType 2 diabetes Other conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT04028960
IN Insulin in Type 1 Diabetes (T1D) Hypoglycemia Unawareness: Safety Only Phase
Not yet reported HealthPartners Institute 4 participants Est. completion 2020-04-08 1 siteOther conditions: Type1diabetesView official trial listing → -
Completed NCT NCT04031599
Assessment of the Efficacy of the Artificial Pancreas Combined With a Qualitative Meal Size Estimation to Control Postprandial Glucose Levels
Not yet reported Institut de Recherches Cliniques de Montreal 30 participants Est. completion 2021-12-14 2 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT04044534
Intranasal Insulin for Posttraumatic Stress Disorder
Not yet reported VA Connecticut Healthcare System 10 participants Est. completion 2026-05-28 1 site Stand-aloneOther conditions: PTSDView official trial listing → -
Completed NCT NCT04049123
A Study of LY900014 in Healthy Chinese Participants
Not yet reported Eli Lilly and Company 15 participants Est. completion 2020-10-23 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT04079881
Glucagon Response to Prandial Insulin Administration in Persons With Type 1 Diabetes
Not yet reported, Not yet reported Washington University School of Medicine 1 participants Est. completion 2020-07-01 1 site Stand-aloneOther conditions: Type 1 Diabetes, Hyperglycemia, PostprandialView official trial listing → -
Completed NCT NCT04100473
Dose Response of Dance 501 in Subjects With Type 2 Diabetes Mellitus
Not yet reported Dance Biopharm Inc. 24 participants Est. completion 2019-08-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04112069
The Insulin-Only Bionic Pancreas Bridging Study- Pediatric Transitional Study
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2018-11-19 3 sites Stand-aloneOther conditions: Type1 Diabetes MellitusView official trial listing → -
Terminated NCT NCT04115384
Intranasal Insulin in Frontotemporal Dementia (FTD)
Not yet reported HealthPartners Institute 3 participants Est. completion 2023-05-15 1 siteOther conditions: Frontotemporal Dementia, Behavioral VariantView official trial listing → -
Completed NCT NCT04124302
The Impact of Two Different Insulin Dose Calculation on Postprandial Glycemia After Mixed Meal.
Not yet reported Medical University of Warsaw 76 participants Est. completion 2024-12-31 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT04149262
Fiasp® Versus NovoRapid® in Children With Type 1 Diabetes on MiniMed 640G Pump With Sensor
Aristotle University Of Thessaloniki 44 participants Est. completion 2023-02-15 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT04154449
Effect of Intranasal Insulin on Postoperative Cognitive Dysfunction
Minia University 57 participants Est. completion 2019-12-25 2 sitesOther conditions: Middle Aged PatientsView official trial listing → -
Completed NCT NCT04157738
A Study of Rapid-Acting Mealtime Insulin in Children and Adolescents With Newly Diagnosed Type 1 Diabetes Mellitus
Not yet reported Emory University 24 participants Est. completion 2020-12-17 1 siteOther conditions: Diabetes Mellitus, Type 1 DiabetesView official trial listing → -
Completed NCT NCT04161976
A Study of LY900027 Given by Insulin Pump to Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 20 participants Est. completion 2020-07-14 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT04196231
Durability of Combination of Insulin and GLP-1 Receptor Agonist or SGLT-2 Inhibitors Versus Basal Bolus Insulin Regimen in Type 2 Diabetes (BEYOND)
Not yet reported University of Campania Luigi Vanvitelli 258 participants Est. completion 2020-10-20 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04200313
The Insulin-Only Bionic Pancreas Pivotal Trial
Not yet reported Jaeb Center for Health Research 440 participants Est. completion 2022-01-14 16 sitesOther conditions: Diabetes Mellitus, Type 1 Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT04235439
PK/PD Biosimilarity Study of Gan & Lee Insulin Lispro Injection vs. EU and US Humalog® in Healthy Males
Not yet reported Gan and Lee Pharmaceuticals, USA 36 participants Est. completion 2019-07-03 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04243629
Co-administration of Pramlintide and Insulin Via an Automated Dual-hormone Artificial Pancreas System in Adults With Type 1 Diabetes
Not yet reported McGill University 26 participants Est. completion 2024-04 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1, Type 1 Diabetes, Postprandial HyperglycemiaView official trial listing → -
Completed NCT NCT04251585
Intranasal Insulin in Parkinson's Disease
Not yet reported HealthPartners Institute 31 participants Est. completion 2024-08-27 1 site Stand-aloneOther conditions: Parkinson DiseaseView official trial listing → -
Withdrawn NCT NCT04254380
Gan & Lee Evaluation of New Biosimilar for Type 1 Lispro
Not yet reported Gan and Lee Pharmaceuticals, USA Est. completion 2020-01-27 107 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT04276207
A Study of LY900014 Versus Insulin Lispro (Humalog) on High Blood Sugar in Participants With Type 1 Diabetes Who Use Insulin Pumps
Not yet reported Eli Lilly and Company 32 participants Est. completion 2020-08-10 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT04292535
Safety and Efficacy of Combining Intranasal Insulin & Acute Exercise
Not yet reported Michigan State University 116 participants Est. completion 2020-02-20 1 siteOther conditions: Insulin, ExerciseView official trial listing → -
Terminated NCT NCT04416269
Oral Anti Diabetic Agents in the Hospital
Not yet reported Emory University 85 participants Est. completion 2025-04-11 3 sites Added to GLP-1Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT04484779
A Study of an Insulin Management System in Participants With Type 1 or Type 2 Diabetes
Not yet reported Eli Lilly and Company 67 participants Est. completion 2020-12-22 5 sitesType 2 diabetes Other conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT04501107
A Trial to Compare BioChaperone Insulin Lispro Formulations With US Approved Humalog® and With EU Approved Humalog® in Patients With Type 1 Diabetes Mellitus
Not yet reported Adocia 32 participants Est. completion 2020-11-03 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT04537923
A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin
Not yet reported Eli Lilly and Company 1428 participants Est. completion 2022-11-01 135 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04542148
Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes
Not yet reported University of Alabama at Birmingham 120 participants Est. completion 2026-12-31 4 sitesType 2 diabetes Other conditions: Preterm Birth, Pregnancy, High Risk, Diabetes, GestationalView official trial listing → -
Withdrawn NCT NCT04635774
Post Operative Delirium Study
Not yet reported, Not yet reported University of Kansas Medical Center Est. completion 2023-11-14 1 siteOther conditions: DeliriumView official trial listing → -
Completed NCT NCT04687878
The Effect of Intranasal Insulin on Motor and Non-motor Symptoms in Parkinson's Disease Patients
Not yet reported dr.dargahi 28 participants Est. completion 2023-09-20 1 siteOther conditions: Parkinson DiseaseView official trial listing → -
Status unknown NCT NCT04690309
Human Versus Analogue Insulin in Patients After Pancreatectomy.
Not yet reported Polish Society of Diabetology 100 participants Est. completion 2021-12-31 1 siteOther conditions: Pancreatogenous DiabetesView official trial listing → -
Completed NCT NCT04739241
Premixed vs Basal Bolus Insulin Therapy in Older Patients With Type 2 Diabetes
Not yet reported Consorci Sanitari Integral 60 participants Est. completion 2018-06-19Type 2 diabetesView official trial listing → -
Completed NCT NCT04739371
Food Intake and Intra-Nasal Insulin for African American Adults (FIINAAL)
Not yet reported Pennington Biomedical Research Center 40 participants Est. completion 2022-06-07 1 site Stand-aloneOther conditions: InsulinView official trial listing → -
Completed NCT NCT04783376
Effect of Splitting Mealtime Insulin Doses After Mixed Meals High in Fat and Protein
Not yet reported Sohag University 43 participants Est. completion 2022-03-03 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT04816890
A Trial to Assess the Efficacy and Safety of M1 Pram P037 Prandial Insulin in Subjects With Type 1 Diabetes (T1DM)
Not yet reported Adocia 80 participants Est. completion 2022-02-24 2 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04965051
Safety and Efficacy of Insulin Degludec/Insulin Aspart in Patients With T1DM
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 40 participants Est. completion 2023-12 1 siteOther conditions: Type 1 Diabetes Mellitus With Diabetic Gastroparesis, HbA1c, Time in RangeView official trial listing → -
Status unknown NCT NCT04972175
Safety and Efficacy of BC LisPram
Not yet reported Michael Tsoukas 16 participants Est. completion 2022-06 1 siteOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT04974528
Afrezza® INHALE-1 Study in Pediatrics
Not yet reported Mannkind Corporation 319 participants Est. completion 2025-04-29 39 sitesType 2 diabetes Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT04977908
Closing the Loop in Adults With Type 1 Diabetes (CLEAR)
Not yet reported University of Cambridge 26 participants Est. completion 2023-05-31 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05062785
Dose-Finding Study of Intranasal Insulin in Healthy Participants Insulin in Healthy Participants
Not yet reported Robert Silbergleit 24 participants Est. completion 2022-04-25 1 site Stand-aloneOther conditions: Out-Of-Hospital Cardiac Arrest, HealthyView official trial listing → -
Completed NCT NCT05067270
A Study of Infusion Site Pain After Infusion of Excipients in Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 40 participants Est. completion 2021-12-06 2 sites Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT05081219
SNIFF - Combo INI+EMPA Trial
Not yet reported Wake Forest University Health Sciences 47 participants Est. completion 2024-09-17 1 site Stand-aloneOther conditions: Mild Cognitive Impairment, Cognitive Impairment, Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT05104424
The Study of Quadruple Therapy Intranasal Insulin, Zinc, Gabapentin, Ice Cube Stimulation for Post COVID-19 Smell and Taste Dysfunctions
Not yet reported Ministry of Health, Saudi Arabia 22 participants Est. completion 2022-10-01Other conditions: Smell Dysfunction, Taste Disorders, Taste Disorder, Secondary, Sweet, Taste Disorder, Secondary, Bitter, Smell DisorderView official trial listing → -
Suspended NCT NCT05153395
Impact of Intranasal Insulin on Sympathetic Activity and Cerebral Vasodilation
Not yet reported University of Missouri-Columbia 65 participants Est. completion 2027-06 1 siteOther conditions: Healthy, Vasodilation, Insulin Resistance, Autonomic Dysfunction, ObesityView official trial listing → -
Completed NCT NCT05218915
Basal Plus GLP1-ra on Glycemic Variability in CKD
Not yet reported Elaine Chow 95 participants Est. completion 2024-10-30 1 siteChronic kidney disease Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT05257460
Closing the Loop in Adults With Type 1 Diabetes Under Free Living Conditions (AP@Home04_Phase 4)
Not yet reported University of Cambridge 28 participants Est. completion 2023-03-25 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05262387
A Study of LY900014 (Lyumjev) Versus Insulin Lispro (Humalog) in Participants With Type 1 Diabetes
Not yet reported Eli Lilly and Company 25 participants Est. completion 2023-03-07 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT05325294
Evaluation of the Advanced Hybrid Closed Loop (AHCL) System in Type 1 Adults and Pediatrics Utilizing Lyumjev®
Not yet reported Medtronic MiniMed, Inc. 244 participants Est. completion 2024-01-03 19 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05373186
A Trial Investigating the Pharmacodynamics of BC Combo THDB0207 Compared With Humalog® Mix25 and Simultaneous Injections of Humalog® and Lantus® in Healthy Chinese Volunteers
Not yet reported Adocia 27 participants Est. completion 2022-12-04 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT05373199
A Trial Comparing the Pharmacodynamics and Pharmacokinetics of BC Combo THDB0207 and Lantus® and Humalog® in Subjects With Type 1 Diabetes
Not yet reported Adocia 30 participants Est. completion 2022-10-28 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05373212
A Trial Investigating the Dose Linearity and Safety of BC Combo THDB0207 in Subjects With Type 2 Diabetes
Not yet reported Adocia 40 participants Est. completion 2023-01-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05457933
Efficacy and Safety of Dapagliflozin for the Hospital Management of Patients With Type 2 Diabetes
Not yet reported Medanta, The Medicity, India 250 participants Est. completion 2023-01-14 1 siteCardiovascular disease Other conditions: Type2diabetesView official trial listing → -
Completed NCT NCT05461365
Intranasal Insulin for COVID-19-related Smell Loss
Not yet reported Universidad Panamericana 27 participants Est. completion 2021-12-20 1 site Stand-aloneOther conditions: Anosmia, Smell Loss, Paraosmia, Hyposmia, COVID-19View official trial listing → -
Completed NCT NCT05462756
A Study of Insulin Efsitora Alfa (LY3209590) as a Weekly Basal Insulin Compared to Insulin Glargine in Adult Participants With Type 2 Diabetes on Multiple Daily Injections
Not yet reported Eli Lilly and Company 730 participants Est. completion 2024-02-27 81 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05463744
A Study of Insulin Efsitora Alfa (LY3209590) Compared With Insulin Degludec in Participants With Type 1 Diabetes Treated With Multiple Daily Injection Therapy
Not yet reported Eli Lilly and Company 692 participants Est. completion 2024-05-07 83 sitesOther conditions: Type 1 Diabetes, DiabetesView official trial listing → -
Completed NCT NCT05508061
Ultrarapid Insulin Administered by a Bihormonal Closed Loop System in Patients With Type 1 Diabetes
Not yet reported Inreda Diabetic B.V. 12 participants Est. completion 2023-03-16 3 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05543850
Portable Artificial Pancreas Applied for Youth and Adolescents
Not yet reported Inreda Diabetic B.V. 20 participants Est. completion 2023-05-19 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT05565976
Dapagliflozin Effect in Cognitive Impairment in Stroke Trial
Not yet reported, Not yet reported Jaime Daniel Mondragon 270 participants Est. completion 2025-07-01 1 siteCardiovascular diseaseMetabolic syndrome Other conditions: Mild Cognitive Impairment, Dementia, VascularView official trial listing → -
Completed NCT NCT05571878
Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents
Not yet reported Centre for Addiction and Mental Health 24 participants Est. completion 2025-05-13 1 site Stand-aloneOther conditions: Major Depressive Disorder, DepressionView official trial listing → -
Completed NCT NCT05579119
SITAgliptin Plus GLARgine to Glycemic Control in the Hospital Setting (SITAGLAR-H)
Not yet reported Hospital de Especialidades, Centro Medico Nacional "La Raza", Instituto Mexicano del Seguro Social 76 participants Est. completion 2023-08-24 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05613491
Intranasal Insulin Improves Postoperative Neurocognitive Disorders in Elderly Patients
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 438 participants Est. completion 2023-08-31 1 site Stand-aloneOther conditions: Postoperative Neurocognitive DisordersView official trial listing → -
Status unknown NCT NCT05660941
Automated Fully Closed-Loop Insulin Delivery in Type 1 Diabetes With Ultra-Rapid Lispro (ACOLYTE Study)
Not yet reported Manchester University NHS Foundation Trust 26 participants Est. completion 2024-05-01 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Not yet recruiting NCT NCT05689424
Suppression of Endogenous Glucose Production by Injectable HDV-Insulin Lispro: A Dose Response Study in Human Subjects With Type 1 Diabetes
Not yet reported University of California, San Diego 18 participants Est. completion 2026-06-30Other conditions: Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT05726461
Efficacy and Safety of Android Artificial Pancreas System in Adult Patients With Type 1 Diabetes Mellitus in China
Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 25 participants Est. completion 2024-09-30 1 siteOther conditions: Diabetes Mellitus, Diabetes Mellitus, Type 1, Glucose Metabolism Disorders, Metabolic Disease, Endocrine System Diseases, Autoimmune Diseases, Immune System DiseasesView official trial listing → -
Active, not recruiting NCT NCT05748990
Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in Schizophrenia
Not yet reported Centre for Addiction and Mental Health 20 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Schizophrenia, HealthyView official trial listing → -
Completed NCT NCT05834868
Efficacy and Safety of THDB0206 Compared to Insulin Lispro Injection in Participants With Type 2 Diabetes
Not yet reported Tonghua Dongbao Pharmaceutical Co.,Ltd 1040 participants Est. completion 2024-12-31 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT05866367
Measurement of Insulin Levels in Cerebral Spinal Fluid (CSF) of Healthy Adults After a Single Intranasal Dose
Not yet reported HealthPartners Institute 2 participants Est. completion 2024-06-28 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05893797
A Study of LY8888AX in Participants Using a Connected Insulin Management Platform
Not yet reported Eli Lilly and Company 36 participants Est. completion 2024-09-16 9 sites Stand-aloneType 2 diabetes Other conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT06144255
Dose-Dependent Effect of Intranasal Insulin in Humans Using Functional Magnetic Resonance Imaging (fMRI)
Not yet reported Florian Schmitzberger 6 participants Est. completion 2024-02-22 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT06153329
A Trial to Evaluate the Pharmacokinetics and Pharmacodynamics of THDB0206 Injection in Healthy Chinese Subjects
Not yet reported Tonghua Dongbao Pharmaceutical Co.,Ltd 39 participants Est. completion 2022-06-06 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT06238778
Phase 2b Trial Comparing HDV-Insulin Lispro to Insulin Lispro in Adults With Type 1 Diabetes Receiving Insulin Degludec
Not yet reported Diasome Pharmaceuticals 227 participants Est. completion 2025-12-16 27 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Active, not recruiting NCT NCT06295640
Relative Contribution of Brain Insulin Action for Postprandial Metabolism
Not yet reported University of Ulm 31 participants Est. completion 2026-06 1 site Stand-aloneOther conditions: Glucose Metabolism DisordersView official trial listing → -
Status unknown NCT NCT06346366
Glucose Control Through a Bihormonal Artificial Pancreas in Patients After Total Pancreatectomy
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 40 participants Est. completion 2024-04-01 1 site Stand-aloneOther conditions: Pancreatic Neoplasms, Type 3c Diabetes, Total PancreatectomyView official trial listing → -
Completed NCT NCT06370715
A Study of LY900014 in Adult Participants With Type 2 Diabetes Mellitus in India
Not yet reported Eli Lilly and Company 150 participants Est. completion 2025-09-02 12 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT06391853
Investigating Brain Insulin Resistance in Alzheimer Disease with IntraNasal Insulin : a Multimodal Neuroimaging Study
Not yet reported Erasme University Hospital Est. completion 2026-10-01 Stand-aloneOther conditions: Alzheimer Disease, Mild Cognitive ImpairmentView official trial listing → -
Withdrawn NCT NCT06434038
Measurement of Insulin Levels in the Cerebrospinal Fluid of Healthy Adults After a Single Intranasal Dose - Middle Age
Not yet reported HealthPartners Institute Est. completion 2026-02-28 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT06443957
The Preventive Effect of Different Doses of Intranasal Insulin on Postoperative Delirium
Not yet reported The First Hospital of Jilin University 129 participants Est. completion 2024-04-13 1 site Stand-aloneOther conditions: Postoperative DeliriumView official trial listing → -
Active, not recruiting NCT NCT06552130
The Importance of Insulin Action in the Brain for the Immune System During Physical Activity
Not yet reported University of Ulm 20 participants Est. completion 2026-09 1 site Stand-aloneOther conditions: Insulin SensitivityView official trial listing → -
Not yet recruiting NCT NCT06600776
Mealtime or Post-meal Dosing of URLi in Medtronic 780G Hybrid Closed Loop System
Not yet reported Tel-Aviv Sourasky Medical Center 50 participants Est. completion 2025-10-21 1 siteOther conditions: Type 1 Diabetes (T1D)View official trial listing → -
Completed NCT NCT06741566
Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.
Not yet reported Minia University 150 participants Est. completion 2026-05-15 1 siteOther conditions: Post Operative Cognitive DysfunctionView official trial listing → -
Enrolling by invitation NCT NCT06765655
Perioperative Glucose Monitoring and Treatment to Reduce Risk of Surgical Site Infections and Complications
Not yet reported St. Peter's Hospital, Albany, NY 266 participants Est. completion 2025-01-31 1 siteOther conditions: Surgical Site Infections, Stress HyperglycemiaView official trial listing → -
Completed NCT NCT06948760
Testing a Conversion Factor for a More Rapidly Acting Insulin in an Automated Insulin Delivery System Among Adolescents With T1D
Not yet reported Mark D. DeBoer, MD, MSc., MCR 11 participants Est. completion 2026-03-10 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT07090824
Subcutaneous Pharmacokinetic Evaluation of Monomeric Insulin and Lyumjev in Adults With Type 1 Diabetes
Not yet reported Stanford University 10 participants Est. completion 2026-05-29 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1, Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT07165652
Study to Demonstrate Pharmacokinetic and Pharmacodynamic Similarity Between NKF-INS(L), US-Humalog®, and EU-Humalog®
Not yet reported Xentria, Inc. 54 participants Est. completion 2026-03-02 1 siteOther conditions: Healthy Male Adult VolunteersView official trial listing → -
Not yet recruiting NCT NCT07252752
Dopamine and Insulin in Psychosis
Not yet reported Medical University of Vienna 46 participants Est. completion 2029-01-01 1 site Stand-aloneOther conditions: First Episode Psychosis (FEP)View official trial listing → -
Completed NCT NCT07282054
Efficacy and Safety of THDB0206 Compared to Insulin Lispro Injection in Participants With Type 1 Diabetes
Not yet reported Tonghua Dongbao Pharmaceutical Co.,Ltd 550 participants Est. completion 2025-01-24 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Not yet recruiting NCT NCT07466173
The Importance of Insulin Action in the Brain for the Immune System During Physical Activity-Overweight
Not yet reported University of Ulm 8 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Insulin SensitivityView official trial listing → -
Enrolling by invitation NCT NCT07521371
Intranasal Insulin for Autism Spectrum Disorder in Children and Young Adults Aged 4 to 21 Years
Healing Hope International 12 participants Est. completion 2030-01-30 1 siteOther conditions: Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Autism Spectrum Disorder High-Functioning, Autism Spectrum Disorder With Absence of Functional Language, Autism Spectrum Disorder With Impaired Functional Language, Autistic Disorder of Childhood Onset With Full Syndrome, Autistic Disorders Spectrum, Autistic Disorder, Autistic Disorder in Children and Adolescents, Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental AbnormalitiesView official trial listing → -
Completed NCT NCT07532577
Intranasal Insulin to Prevent Intensive Care Unit Delirium
Not yet reported, Not yet reported Radboud University Medical Center 30 participants Est. completion 2026-07-30 1 site Stand-aloneOther conditions: Delirium - PostoperativeView official trial listing → -
Not yet recruiting NCT NCT07720479
Intranasal Insulin for Postoperative Delirium in Older Patients With T2DM
Not yet reported Weidong Mi 210 participants Est. completion 2028-02-01 Stand-aloneOther conditions: Postoperative Delirium (POD)View official trial listing → -
Not yet recruiting NCT NCT07756294
Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease
Not yet reported Wake Forest University Health Sciences 30 participants Est. completion 2028-04 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Intranasal insulin, Humalog
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