About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
GZR18
- Company
- Gan & Lee Pharmaceuticals.
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 3 recruiting
Efficacy results: Not yet reported
3 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Nov 12, 2026
Find a Clinical Trial Near Me
See recruiting studies for GZR18 and check eligibility with the study team.
Trial details
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Recruiting NCT NCT07150975
Phase III Clinical Study Comparing the Efficacy and Safety of GZR18 Injection and Semaglutide (Wegovy®) in Adult Obese or Overweight Subjects
Not yet reported Gan & Lee Pharmaceuticals. 420 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Obesity/Overweight in AdultView official trial listing → -
Recruiting NCT NCT07493057
Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Not Treated With Positive Airway Pressure (PAP) Therapy
Not yet reported Gan & Lee Pharmaceuticals. 140 participants Est. completion 2027-11-14 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Recruiting NCT NCT07501832
Evaluate the Efficacy and Safety of GZR18 Injection in Obese Subjects With Obstructive Sleep Apnea Receiving Positive Airway Pressure (PAP) Therapy
Not yet reported Gan & Lee Pharmaceuticals. 140 participants Est. completion 2028-09-28 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT05328726
Single, Ascending Dose, First Time in Human Study for GZR18 in Healthy Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 24 participants Est. completion 2023-03-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06256523
A Study of GZR18 Injection in Chinese Adult Patients With Type 2 Diabetes Mellitus (T2DM)
Not yet reported, Not yet reported Gan and Lee Pharmaceuticals, USA 72 participants Est. completion 2023-09-28 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06256536
A Study of GZR18 Injection in Chinese Obese/Overweight Patients
Not yet reported, Not yet reported Gan and Lee Pharmaceuticals, USA 60 participants Est. completion 2023-10-22 1 site Stand-aloneOther conditions: Obesity, OverweightView official trial listing → -
Status unknown NCT NCT06256549
A Study of GZR18 Injection in Chinese Patients With Type 2 Diabetes Mellitus
Not yet reported Gan and Lee Pharmaceuticals, USA 272 participants Est. completion 2024-07-20 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06256562
A Study of GZR18 Injection in Obese/Overweight Patients
Not yet reported Gan and Lee Pharmaceuticals, USA 340 participants Est. completion 2024-06-05 1 site Stand-aloneOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT06548945
A Phase I Study of GZR18 Injection in Obese/Overweight Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 16 participants Est. completion 2023-08-14 1 site Stand-aloneOther conditions: Overweight and ObesityView official trial listing → -
Completed NCT NCT06548997
A Phase I Study of GZR18 Injection in Healthy Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 57 participants Est. completion 2022-10-20 1 site Stand-aloneType 2 diabetes Other conditions: Overweight and ObesityView official trial listing → -
Status unknown NCT NCT06554054
A Study of GZR18 Tablet in Chinese Healthy Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 92 participants Est. completion 2024-12-09 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT06670209
A Phase I Clinical Study to Evaluate the Effect of GZR18 Injection on the Pharmacokinetics of Oral Metformin Hydrochloride Tablets in Overweight/Obese Subjects
Not yet reported Gan and Lee Pharmaceuticals, USA 32 participants Est. completion 2025-03-19 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06728124
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Obese/Overweight Subjects
Not yet reported Gan & Lee Pharmaceuticals. 640 participants Est. completion 2026-03-26 1 site Stand-aloneOther conditions: Obesity/OverweightView official trial listing → -
Completed NCT NCT06737042
Efficacy and Safety of GZR18 Every 2 Weeks Versus Tirzepatide and Placebo in Obese or Overweight Participants
Not yet reported Gan and Lee Pharmaceuticals, USA 326 participants Est. completion 2026-02-27 20 sites Stand-aloneOther conditions: Obesity and OverweightView official trial listing → -
Completed NCT NCT06777238
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Subjects With Type 2 Diabetes Mellitus and Poor Blood Glucose Control by Diet and Exercise
Not yet reported Gan & Lee Pharmaceuticals. 274 participants Est. completion 2026-07-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06778967
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus
Not yet reported Gan & Lee Pharmaceuticals. 1133 participants Est. completion 2026-09-18 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06974487
A Phase I Study to Evaluate the PK and PD Profiles of GZR102 Injection Versus GZR4 Injection and GZR18 Injection Given Separately in Chinese Adult Overweight Subjects
Not yet reported Gan & Lee Pharmaceuticals. 30 participants Est. completion 2025-09-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07055386
A Study to Compare the Efficacy and Safety of GZR102 Injection and GZR18 Injection in Type 2 Diabetes Mellitus
Not yet reported Gan & Lee Pharmaceuticals. 90 participants Est. completion 2027-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07119450
The Study of [14C] GZR18
Not yet reported Gan & Lee Pharmaceuticals. 6 participants Est. completion 2025-08-13 1 site Stand-aloneOther conditions: Overweight, Obese, ObesityView official trial listing → -
Completed NCT NCT07128888
Study on Gastric Emptying Effect and Drug-Drug Interactions of GZR18 Injection
Not yet reported Gan & Lee Pharmaceuticals. 60 participants Est. completion 2026-04-13 1 site Stand-aloneOther conditions: Obesity or OverweightView official trial listing → -
Completed NCT NCT07141030
Study of Pharmacokinetics and Safety of GZR18 Injection in Subjects With Renal Impairment and Normal Renal Function
Not yet reported Gan & Lee Pharmaceuticals. 32 participants Est. completion 2025-10-20 1 site Stand-aloneOther conditions: Obesity/OverweightView official trial listing → -
Completed NCT NCT07144098
Study of Pharmacokinetics and Safety of GZR18 Injection in Subjects With Liver Insufficiency and Normal Liver Function
Not yet reported Gan & Lee Pharmaceuticals. 24 participants Est. completion 2026-04-07 1 site Stand-aloneOther conditions: Obesity/OverweightView official trial listing → -
Completed NCT NCT07292441
Extension Study of the Phase 3 Clinical Study of GZR18 Injection for Weight Loss
Not yet reported Gan & Lee Pharmaceuticals. 224 participants Est. completion 2026-09-22 1 site Stand-aloneOther conditions: Overweight or ObesityView official trial listing → -
Completed NCT NCT07355738
Bioequivalence Study of GZR18 Injection Before and After CMC Change
Not yet reported Gan & Lee Pharmaceuticals. 266 participants Est. completion 2026-05-22 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07622810
BALANCE-OBS: Bofanglutide (GZR18) Versus Semaglutide in Latin American Adults With Overweight or Obesity
Not yet reported Carnot Laboratories 352 participants Est. completion 2027-12 6 sites Stand-aloneOther conditions: Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07628985
BALANCE-DM2 Study of Bofanglutide in Adults With Type 2 Diabetes
Not yet reported Carnot Laboratories 374 participants Est. completion 2027-10 7 sites Stand-aloneType 2 diabetesView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: GZR18, GZR18 injection
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.