About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Glucagon Infusion
- Company
- The University of Texas Health Science Center at San Antonio
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 2 recruiting
Efficacy results: Not yet reported
2 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Find a Clinical Trial Near Me
See recruiting studies for Glucagon Infusion and check eligibility with the study team.
Trial details
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Recruiting NCT NCT06424106
Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 Diabetes
Not yet reported Mayo Clinic 60 participants Est. completion 2027-07-01 1 sitePrediabetesView official trial listing → -
Recruiting NCT NCT07212868
The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery
Not yet reported The University of Texas Health Science Center at San Antonio 150 participants Est. completion 2030-06-30 2 sitesOther conditions: Non-DiabeticView official trial listing → -
Completed NCT NCT01232244
Oxyntomodulin, Mechanisms of Action in Relation to Appetite, Food Intake, Gastric Emptying and Energy Expenditure.
University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2012-01 1 siteOther conditions: Incretin Action, ObesityView official trial listing → -
Completed NCT NCT01261052
Real-time Adaptation to Changes in Insulin Sensitivity
Not yet reported Legacy Health System 14 participants Est. completion 2011-04 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01297946
Closed-loop Control of Glucose Levels in the Context of Exercise in Adults With Type-1 Diabetes
Not yet reported, Not yet reported Institut de Recherches Cliniques de Montreal 15 participants 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01552603
Artificial Pancreas Control System in an Inpatient Setting
Not yet reported Legacy Health System 14 participants Est. completion 2013-09 2 sites Stand-aloneOther conditions: Type I Diabetes MellitusView official trial listing → -
Completed NCT NCT01754337
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 24 Hours in Adults and Adolescents With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 30 participants Est. completion 2014-06 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01871870
Artificial Pancreas Control System in an Outpatient Setting
Not yet reported Legacy Health System 20 participants Est. completion 2013-10 1 site Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01930110
Closed-loop Control of Glucose Levels (Artificial Pancreas) During Exercise in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 15 participants Est. completion 2015-04 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01966393
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 60 Hours in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 23 participants Est. completion 2015-04 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02010827
Endogenous Glucoseproduction in Patients With Type 2 Diabetes Mellitus During Oral Glucose and iv. Glucose Infusion
University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2015-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02081001
PK/PD Study With G-Pump (Glucagon Infusion) in T1DM Patients
Not yet reported Xeris Pharmaceuticals 19 participants Est. completion 2014-09 1 site Stand-aloneOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02189694
Closed-loop Control of Overnight Glucose Levels (Artificial Pancreas) in Children With Type 1 Diabetes in a Diabetes Camp
Not yet reported Institut de Recherches Cliniques de Montreal 33 participants Est. completion 2014-08 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02416765
Closed-loop Control of Postprandial Glucose Levels in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 15 participants Est. completion 2015-10 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Withdrawn NCT NCT02490098
Closed-loop Control of Postprandial Glucose Levels in Children and Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal Est. completion 2018-07 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02733588
Delivery of G-Pump™ (Glucagon Infusion) From an OmniPod® to Prevent Hypoglycemia in Post-Bariatric Surgery Patients
Not yet reported Xeris Pharmaceuticals 8 participants Est. completion 2017-06-01 1 site Stand-aloneOther conditions: Hypoglycemia, Complications of Bariatric ProceduresView official trial listing → -
Completed NCT NCT02748369
In Vivo Assessment of Cellular Metabolism in Humans
Not yet reported K. Sreekumaran Nair 17 participants Est. completion 2017-03-02 1 siteOther conditions: Normal Cellular MetabolismView official trial listing → -
Active, not recruiting NCT NCT02817659
To Determine Tolerability to Glucagon Infusion in Obese Subjects
Not yet reported AdventHealth Translational Research Institute 20 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: ObesityView official trial listing → -
Completed NCT NCT02937558
CSI-Glucagon for Prevention of Hypoglycemia in Children With Congenital Hyperinsulinism
Not yet reported Xeris Pharmaceuticals 5 participants Est. completion 2018-10 5 sitesOther conditions: Congenital HyperinsulinismView official trial listing → -
Completed NCT NCT03061227
Characterization of Metabolic and Brain Effects of Rising Glucagon During an Oral Glucose Challenge
Not yet reported University Hospital Tuebingen 32 participants Est. completion 2020-04-30 1 siteMetabolic syndrome Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT03490942
Glucagon Infusion in T1D Patients With Recurrent Severe Hypoglycemia: Effects on Counter-Regulatory Responses
Not yet reported Xeris Pharmaceuticals 49 participants Est. completion 2020-02-10 5 sitesOther conditions: Hypoglycemia Unawareness, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03526445
Hepatic Metabolic Changes in Response to Glucagon Infusion
Not yet reported Steno Diabetes Center Copenhagen 27 participants Est. completion 2019-06-12 1 siteOther conditions: Non-Alcoholic Fatty Liver Disease, Total Pancreatectomy, Diabetes MellitusView official trial listing → -
Completed NCT NCT04300049
Effect of Physiologic Hyperglucogonemia on Adipocyte Metabolism
Not yet reported The University of Texas Health Science Center at San Antonio 10 participants Est. completion 2023-11-15 2 sites Stand-aloneOther conditions: Insulin SensitivityView official trial listing → -
Completed NCT NCT04307797
Effect of Glucagon and Glucagon-like Peptide-1 Co-agonism on Cardiac Function and Metabolism in Overweight Participants with Type 2 Diabetes
Not yet reported Cambridge University Hospitals NHS Foundation Trust 10 participants Est. completion 2022-10-07 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT05056584
The Role of the Kidneys and Liver in the Elimination of Glucagon
Not yet reported University Hospital, Gentofte, Copenhagen 48 participants Est. completion 2023-03-28 1 site Stand-aloneChronic kidney disease Other conditions: Liver Cirrhosis, HyperglucagonemiaView official trial listing → -
Completed NCT NCT05669547
Dual Hormone Closed Loop in Type 1 Diabetes
Not yet reported UMC Utrecht 243 participants Est. completion 2025-10-15 14 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1, Diabetes type1, DiabetesView official trial listing → -
Status unknown NCT NCT06154096
Liver Fat and Glucagon Resistance
Imperial College London 20 participants Est. completion 2024-09Other conditions: Steatosis of LiverView official trial listing → -
Status unknown NCT NCT06498063
The Underlying Mechanisms Regarding the Effect of Glucagon on the Kidneys Will be Investigated in Healthy Males.
Not yet reported Ali Asmar 10 participants Est. completion 2025-07-31 1 site Stand-aloneOther conditions: Kidney DiseasesView official trial listing → -
Completed NCT NCT06685146
The Glucose-Independent Effects of Exogenous Glucagon on Insulin Secretion and Cognitive Function in Healthy Subjects
Not yet reported Nicolai Jacob Wewer Albrechtsen 15 participants Est. completion 2025-07-21 1 site Stand-aloneOther conditions: Glucose Metabolism, Insulin SecretionView official trial listing → -
Not yet recruiting NCT NCT06872060
The Effects of Glucagon on Renal Regional Blood Flow in Humans Measured by Magnetic Resonance.
Not yet reported Bispebjerg Hospital 10 participants Est. completion 2027-11-01 Stand-aloneOther conditions: Kidney DiseasesView official trial listing → -
Active, not recruiting NCT NCT06877208
The Effect of Glucagon on Cerebral Glucose Metabolism in Healthy Humans
Not yet reported Nicolai Jacob Wewer Albrechtsen 12 participants Est. completion 2027-08 1 site Stand-aloneOther conditions: Cerebral Glucose MetabolismView official trial listing → -
Completed NCT NCT06921824
Investigating the Acute Effects of Increasing Glucagon Exposure in Healthy Participants
Not yet reported Nicolai Jacob Wewer Albrechtsen 16 participants Est. completion 2025-09-19 1 site Stand-aloneOther conditions: Glucose Metabolism, GlucagonView official trial listing → -
Not yet recruiting NCT NCT07300982
Studies of Insulin and Glucagon Action in the Liver
Not yet reported, Not yet reported Duke University 40 participants Est. completion 2029-12 1 site Stand-aloneOther conditions: Diabetes (DM)View official trial listing → -
Active, not recruiting NCT NCT07366710
Measuring Amino Acid and Glucose Metabolism in Healthy Volunteers and NAFLD Patients Using Total-body PET
Not yet reported Rigshospitalet, Denmark 36 participants Est. completion 2027-10 1 site Stand-aloneMASLD Other conditions: Glucose MetabolismView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
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