About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
GlucaGen
- Company
- Zealand Pharma
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 190 recruiting
Efficacy results: Not yet reported
190 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 1, 2026
Find a Clinical Trial Near Me
See recruiting studies for GlucaGen and check eligibility with the study team.
Trial details
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Recruiting NCT NCT00992901
Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery
Not yet reported The University of Texas Health Science Center at San Antonio 160 participants Est. completion 2027-08 2 sitesOther conditions: Post Bariatricsurgery, HypoglycemiaView official trial listing → -
Recruiting NCT NCT01803451
Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
Not yet reported The University of Texas Health Science Center at San Antonio 80 participants Est. completion 2027-08 2 sitesOther conditions: Post-bariatric SurgeryView official trial listing → -
Recruiting NCT NCT01851694
Beta-cell Response to Incretin Hormones in Cystic Fibrosis
Not yet reported University of Pennsylvania 45 participants Est. completion 2026-12 1 siteOther conditions: Cystic Fibrosis, Pancreatic InsufficiencyView official trial listing → -
Recruiting NCT NCT03087032
Liraglutide-bolus vs Glargine-bolus Therapy in Overweight/Obese Type 2 Diabetes Patients (LiraGooD)
Not yet reported The First Affiliated Hospital of Xiamen University 164 participants Est. completion 2025-02-10 1 siteType 2 diabetes Other conditions: Overweight and Obesity, Hyperglycaemia (Diabetic)View official trial listing → -
Recruiting NCT NCT03883412
Effect of Exercise and/or Liraglutide on Vascular Dysfunction and Insulin Sensitivity in Type 2 Diabetes ( ZQL007)
Not yet reported University of Virginia 60 participants Est. completion 2027-12 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT03987308
Comparing the Efficacy and Safety Between Continuous Subcutaneous Beinaglutide and CSII for Newly Diagnosed T2DM Patients
Not yet reported Beijing Hospital 115 participants Est. completion 2025-12 16 sitesType 2 diabetes Other conditions: Type 2 Diabetic PatientsView official trial listing → -
Recruiting NCT NCT04200391
Very Low Carbohydrate Diets and Glucagon Response in T1DM
Not yet reported Boston Children's Hospital 12 participants Est. completion 2026-07-31 1 siteOther conditions: Type1diabetesView official trial listing → -
Recruiting NCT NCT04575844
Effects of Exercise and GLP-1 Agonism on Muscle Microvascular Perfusion and Insulin Action in Adults With Metabolic Syndrome
Not yet reported University of Virginia 80 participants Est. completion 2027-04-30 1 siteMetabolic syndromeView official trial listing → -
Recruiting NCT NCT04629586
The T1D Exchange Registry
T1D Exchange, United States 50000 participants Est. completion 2030-12-31 1 siteOther conditions: Diabetes Mellitus, Type 1, Diabetes, Type 1 Diabetes, Diabetes MellitusView official trial listing → -
Recruiting NCT NCT04731272
GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance
Not yet reported University of Pennsylvania 30 participants Est. completion 2028-06-30 2 sitesOther conditions: Cystic Fibrosis, Pancreatic Insufficiency, Abnormal Glucose Tolerance, DiabetesView official trial listing → -
Recruiting NCT NCT05119179
Pharmacogenetics of the Response to GLP-1 in Mexican-Americans With Prediabetes
Not yet reported The University of Texas Health Science Center, Houston 300 participants Est. completion 2026-10-31 1 sitePrediabetesView official trial listing → -
Recruiting NCT NCT05268237
Safety, Tolerability and Preliminary Efficacy of Sublingual Liraglutide in Patients With Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Biolingus 15 participants Est. completion 2026-03 1 siteOther conditions: Diabete Type 2View official trial listing → -
Recruiting NCT NCT05340868
Genetics of the Acute Response to Oral Semaglutide
Not yet reported Medical University of Bialystok 1000 participants Est. completion 2025-12-31 1 sitePrediabetes Other conditions: Prediabetic State, ObesityView official trial listing → -
Recruiting NCT NCT05375968
Splanchnic Venous Capacitance in Postural Tachycardia Syndrome
Not yet reported Vanderbilt University Medical Center 50 participants Est. completion 2028-06-01 1 siteOther conditions: Postural Tachycardia Syndrome (POTS)View official trial listing → -
Recruiting NCT NCT05390892
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
Not yet reported Brigham and Women's Hospital 6000 participants Est. completion 2029-03-01 36 sitesCardiovascular disease Other conditions: Type2DiabetesView official trial listing → -
Recruiting NCT NCT05478707
Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes
Not yet reported AdventHealth Translational Research Institute 47 participants Est. completion 2028-07-30 1 siteOther conditions: Diabetes Mellitus, Type 1, Endothelial DysfunctionView official trial listing → -
Recruiting NCT NCT05499702
The Effects of Glucagon on Hepatic Metabolism in People With Type 2 Diabetes After Caloric Restriction
Not yet reported Adrian Vella 20 participants Est. completion 2027-12-31 1 siteOther conditions: Type2diabetesView official trial listing → -
Recruiting NCT NCT05501483
Adipose Tissue Heterogeneity and Its Link to Type 2 Diabetes
Not yet reported Karolinska Institutet 60 participants Est. completion 2032-12-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT05553093
Effects of Tirzepatide and Insulin Glargine on Glucolipid Metabolism and Brain Function in Patients With Type 2 Diabetes
Not yet reported Nanjing First Hospital, Nanjing Medical University 150 participants Est. completion 2027-10-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT05662189
Assessment of Pancreatic Beta Cell Mass and Function by Positron Emission Tomography Imaging in Human Diabetes Mellitus
Not yet reported Azienda Ospedaliero-Universitaria di Parma 70 participants Est. completion 2025-12 1 siteOther conditions: Type1diabetes, Type2diabetes, Pre Diabetes, HyperinsulinismView official trial listing → -
Recruiting NCT NCT05663515
A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs
AstraZeneca 24000 participants Est. completion 2026-10-01 8 sitesOther conditions: Pancreatic CancerView official trial listing → -
Recruiting NCT NCT05681299
Effects of GH and Lirglutide on AgRP
Not yet reported Columbia University 40 participants Est. completion 2028-04-30 1 siteOther conditions: Healthy, Growth Hormone DeficiencyView official trial listing → -
Recruiting NCT NCT05708859
Effect of Tirzepatide on Progression of Coronary Atherosclerosis Using MDCT
Not yet reported Matthew J. Budoff 120 participants Est. completion 2026-05 1 siteOther conditions: Type II Diabetes, AtherosclerosisView official trial listing → -
Recruiting NCT NCT05822609
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
Not yet reported University of Washington 60 participants Est. completion 2027-12 4 sitesChronic kidney disease Other conditions: Type 1 DiabetesView official trial listing → -
Recruiting NCT NCT05831085
Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease
Not yet reported Duk-Woo Park, MD 1500 participants Est. completion 2029-12-31 39 sitesOther conditions: Coronary Artery StenosisView official trial listing → -
Recruiting NCT NCT05912621
Tirzepatide: Reversal of Lipotoxicity and Adipose Tissue Dysfunction in Humans With Overweight/Obesity
Not yet reported Stanford University 66 participants Est. completion 2029-12 1 siteOther conditions: Obesity, Overweight and Obesity, OverweightView official trial listing → -
Recruiting NCT NCT05933499
Effect of Tirzepatide and Bimagrumab on Body Composition, Insulin Sensitivity, and Bone in Adults With Obesity
Not yet reported Massachusetts General Hospital 63 participants Est. completion 2029-03-31 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT05938712
The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Kidney Transplant Recipients
Not yet reported University Health Network, Toronto 20 participants Est. completion 2028-03-01 1 siteOther conditions: Kidney Transplant RecipientsView official trial listing → -
Recruiting NCT NCT06003153
GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH
Not yet reported Massachusetts General Hospital 125 participants Est. completion 2027-05-31 1 siteType 2 diabetes Other conditions: Genetic Predisposition, Metabolic DiseasesView official trial listing → -
Recruiting NCT NCT06069622
Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment
Brigham and Women's Hospital 30 participants Est. completion 2026-11-30 1 siteOther conditions: Overweight and ObesityView official trial listing → -
Recruiting NCT NCT06132477
Impact GLP-1 Agonists Following Bariatric
Not yet reported University of Missouri-Columbia 150 participants Est. completion 2030-07 1 siteMetabolic syndromeObstructive sleep apnea Other conditions: Morbid Obesity, Diabetes Mellitus, HypertensionView official trial listing → -
Recruiting NCT NCT06143956
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Not yet reported Eli Lilly and Company 1481 participants Est. completion 2028-02 56 sitesOther conditions: Obesity, OverweightView official trial listing → -
Recruiting NCT NCT06191848
Subcutaneous Tirzepatide Once-weekly in Patients With Obesity and Knee Osteoarthritis (STOP KNEE-OA)
Not yet reported University of Melbourne 352 participants Est. completion 2037-05 4 sitesOsteoarthritis Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT06246799
Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes
Not yet reported The University of Texas Health Science Center at San Antonio 256 participants Est. completion 2029-06-30 2 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT06252493
Value of PET/MR Enterography in the Assessment of Crohn's Disease Using a Collagen-binding Radiotracer.
Massachusetts General Hospital 25 participants Est. completion 2029-12-19 1 siteOther conditions: Crohn DiseaseView official trial listing → -
Recruiting NCT NCT06324461
GLP-1 Receptor Agonist for Reduction of Myocardial Injury After Non-cardiac Surgery
Not yet reported The University of Hong Kong 372 participants Est. completion 2028-12-31 3 sitesOther conditions: Myocardial InjuryView official trial listing → -
Recruiting NCT NCT06361238
Liraglutide in Preventing Delirium in Diabetic Elderly After Cardiac Surgery
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 260 participants Est. completion 2028-03-31 1 siteOther conditions: Delirium, PostoperativeView official trial listing → -
Recruiting NCT NCT06374875
Fibrosis Lessens After Metabolic Surgery
Not yet reported The Cleveland Clinic 120 participants Est. completion 2029-12-31 22 sitesMASLDMASH Other conditions: Non-Alcoholic Fatty Liver Disease, Liver Fibrosis, ObesityView official trial listing → -
Recruiting NCT NCT06387199
Alleviating Carbohydrate Counting for Patients with Type-1 Diabetes Using a Closed Loop System with Weekly Subcutaneous Semaglutide
Not yet reported, Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 26 participants Est. completion 2027-01 1 siteOther conditions: Type 1 Diabetes, Diabetes MellitusView official trial listing → -
Recruiting NCT NCT06424015
Insulin and Insulin Pulses During Fasting
Not yet reported Mayo Clinic 60 participants Est. completion 2027-09-01 1 sitePrediabetesView official trial listing → -
Recruiting NCT NCT06424106
Effect of Glucagon on Fasting Insulin Secretion and Glucose Metabolism in Subjects Without Type 2 Diabetes
Not yet reported Mayo Clinic 60 participants Est. completion 2027-07-01 1 sitePrediabetesView official trial listing → -
Recruiting NCT NCT06439277
A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)
Not yet reported Eli Lilly and Company 300 participants Est. completion 2030-12 69 sitesOther conditions: Obesity, Weight GainView official trial listing → -
Recruiting NCT NCT06461377
The Ameliorative Effects of GLP-1RA on Diabetic Cardiac Autonomatic Neuropathy
Not yet reported The First Affiliated Hospital with Nanjing Medical University 50 participants Est. completion 2027-12-31 1 siteType 2 diabetes Other conditions: Diabetes With Diabetic Autonomic Neuropathy (Diagnosis)View official trial listing → -
Recruiting NCT NCT06470295
Effect of C-peptide on Hypoglycemic Counterregulation
Not yet reported University of Cincinnati 38 participants Est. completion 2028-01-01 1 siteOther conditions: Hypoglycemia, Type 1 DiabetesView official trial listing → -
Recruiting NCT NCT06512584
Efficacy and Safety of PJ009 in Patients With Short Bowel Syndrome Requiring Parenteral Nutrition
Not yet reported Chongqing Peg-Bio Biopharm Co., Ltd. 72 participants Est. completion 2026-04-27 8 sitesOther conditions: Short Bowel SyndromeView official trial listing → -
Recruiting NCT NCT06517212
Tirzepatide Weight Loss for MRD+ Early Breast Cancer
Not yet reported Baylor Research Institute 48 participants Est. completion 2030-12-31 1 siteOther conditions: Breast Cancer, Breast Neoplasms, Breast CancersView official trial listing → -
Recruiting NCT NCT06518837
Tirzepatide for Weight Loss Intervention in Early-Stage Hormone Receptor Positive/HER2 Negative Breast Cancer
Not yet reported Rutgers, The State University of New Jersey 40 participants Est. completion 2027-09-30 7 sitesOther conditions: Hormone Receptor-Positive Breast Cancer, HER2-Negative Breast CancerView official trial listing → -
Recruiting NCT NCT06528405
The Efficacy and Safety of Sodium-glucose Cotransporter 2 Inhibitors in Patients With Acute Kidney Disease
Not yet reported National Taiwan University Hospital 264 participants Est. completion 2027-12 1 siteOther conditions: Acute Kidney InjuryView official trial listing → -
Recruiting NCT NCT06548490
GLP-1R Agonist Treatment for Opioid Use Disorder
Not yet reported Milton S. Hershey Medical Center 200 participants Est. completion 2027-04-30 4 sitesSubstance use disorder Other conditions: Opioid Abuse and Addiction, Narcotic-Related Disorders, Chemically-Induced Disorders, Mental Disorder, OpioidView official trial listing → -
Recruiting NCT NCT06582875
Glucagon-Like Peptide-1 Receptor Agonist in ADPKD
Not yet reported University of Colorado, Denver 126 participants Est. completion 2029-06-30 1 siteOther conditions: Autosomal Dominant Polycystic Kidney, ObesityView official trial listing → -
Recruiting NCT NCT06592261
Graded Insulin Suppression Test P&F
Not yet reported Columbia University 15 participants Est. completion 2026-09 1 siteOther conditions: Insulin Resistance, Hyperinsulinemia, Obesity, HealthyView official trial listing → -
Recruiting NCT NCT06606821
The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery Disease
Not yet reported Tina Vilsbøll 124 participants Est. completion 2028-08-01 3 sitesCardiovascular disease Other conditions: Coronary Microvascular Dysfunction, Overweight or Obesity, Stable Angina PectorisView official trial listing → -
Recruiting NCT NCT06630585
GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes
Not yet reported University of Bern 42 participants Est. completion 2026-06 3 sitesOther conditions: Type 1 Diabetes (T1D)View official trial listing → -
Recruiting NCT NCT06647368
Development of a Non-invasive Method for Quantifying Cerebral Glucose Metabolism for Studying the Effect of Glucagon in Humans
Not yet reported Nicolai Jacob Wewer Albrechtsen 6 participants Est. completion 2024-12-17 1 siteOther conditions: Cerebral Glucose MetabolismView official trial listing → -
Recruiting NCT NCT06651177
Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder
Not yet reported T. John Winhusen, PhD 310 participants Est. completion 2027-10-31 9 sitesSubstance use disorderView official trial listing → -
Recruiting NCT NCT06654219
Protective Benefits of a Clear Liquid Diet on Residual Gastric Content in Patients Taking Glucagon Like Peptide-1 Receptor (GLP-1 RA) Agonist Prior to Anesthesia
Not yet reported The University of Texas Health Science Center, Houston 136 participants Est. completion 2026-12-31 1 siteOther conditions: Pulmonary AspirationView official trial listing → -
Recruiting NCT NCT06657209
Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide
Not yet reported Stanford University 104 participants Est. completion 2027-12-15 2 sitesType 2 diabetes Other conditions: Diabetes, Pre DiabetesView official trial listing → -
Recruiting NCT NCT06666049
Gastric POCUS for Airway Management in Patients Using Glucagon-like Peptide-1 Receptor Agonist (Multicentric)
Clinica Universidad de Navarra, Universidad de Navarra 39 participants Est. completion 2026-12-01 2 sitesOther conditions: Aspiration PneumoniaView official trial listing → -
Recruiting NCT NCT06671587
iGlarLixi CGM Study in Chinese T2D Individuals After OADs
Not yet reported Sanofi 678 participants Est. completion 2026-09-18 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06706284
Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes
Not yet reported Marzieh Salehi 50 participants Est. completion 2029-03-01 2 sitesType 2 diabetes Other conditions: Spinal Cord InjuriesView official trial listing → -
Recruiting NCT NCT06721507
2024 Tirzepatide-Bariatric Surgery
Not yet reported Marlene Starr 50 participants Est. completion 2026-12-31 1 siteOther conditions: Obesity and Obesity-related Medical Conditions, Bariatric SurgeryView official trial listing → -
Recruiting NCT NCT06725693
Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related Disease
Tianjin Medical University 500 participants Est. completion 2027-11-01 3 sitesOther conditions: GLP1-R-related Disease, Tumor, Insulinoma, Positron Emission TomographyView official trial listing → -
Recruiting NCT NCT06727331
Study of Tirzepatide for Recovery and Alcohol Use Management
Not yet reported Brigham and Women's Hospital 20 participants Est. completion 2027-07-01 2 sitesAlcohol use disorderView official trial listing → -
Recruiting NCT NCT06734312
MAINTAIN (Mucosal AblatIoN Therapy After INcretins)
Not yet reported Dr. Christopher McGowan 20 participants Est. completion 2026-06 2 sites Added to GLP-1Other conditions: Obesity and Obesity-related Medical Conditions, Obesity and Overweight, Obesity Prevention, Obesity Recidivism, GLP-1, Ablation TechniquesView official trial listing → -
Recruiting NCT NCT06742710
Liraglutide Treatment in Obese Infertile PCOS Women
Not yet reported Peking University Third Hospital 890 participants Est. completion 2029-12-31 3 sitesOther conditions: PCOS, Obesity, InfertilityView official trial listing → -
Recruiting NCT NCT06751589
A Study of a Weight Loss Intervention in People With Endometrial Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 36 participants Est. completion 2027-12 7 sitesOther conditions: Endometrial CancerView official trial listing → -
Recruiting NCT NCT06759701
Pre-Surgical Tirzepatide-Assisted Weight Loss in Overweight and Obese Men With Intermediate Risk Prostate Cancer: A Pilot Feasibility Study
Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2028-12-31 1 siteOther conditions: Diabetes, Prostate CancerView official trial listing → -
Recruiting NCT NCT06770621
Longitudinal Study of the GLUcagon REsponse to Hypoglycemia in Children and Adolescents With New-onset Type 1 DIAbetes
Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 1000 participants Est. completion 2025-10-25 1 siteOther conditions: Severe Hypoglycemia, Type1diabetesView official trial listing → -
Recruiting NCT NCT06774079
Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) and Diet in Inflammatory Bowel Disease (IBD) Patients
Not yet reported University of Miami 24 participants Est. completion 2027-03-05 1 siteOther conditions: Crohn DiseaseView official trial listing → -
Recruiting NCT NCT06802081
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation
Not yet reported The Cleveland Clinic 100 participants Est. completion 2027-06-01 1 siteOther conditions: Atrial Fibrillation, ObesityView official trial listing → -
Recruiting NCT NCT06811324
Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults
Not yet reported The University of Texas Health Science Center at San Antonio 20 participants Est. completion 2027-06-01 1 siteOther conditions: Obesity Prevention, Sarcopenia in Elderly, Cardiovascular Function, GLP - 1, Weight LossView official trial listing → -
Recruiting NCT NCT06820281
Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes
Not yet reported Victor Chang Cardiac Research Institute 44 participants Est. completion 2027-12-31 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Recruiting NCT NCT06825182
Current Status of Islet Alpha Cell Function in Patients with Type 2 Diabetes
Not yet reported Nanjing First Hospital, Nanjing Medical University 1000 participants Est. completion 2025-12-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06836284
The Evira Study: Additional Support During Obesity Treatment
Not yet reported Karolinska Institutet 40 participants Est. completion 2027-05-01 3 sitesOther conditions: Childhood Obesity, Treatment AdherenceView official trial listing → -
Recruiting NCT NCT06839248
Effect of Fasting Recommendations Among Patients Using GLP-1 Receptor Agonists
Not yet reported St Vincent's Hospital Melbourne 154 participants Est. completion 2027-02-01 2 sitesOther conditions: Residual Gastric Contents, Pulmonary Aspiration of Gastric ContentsView official trial listing → -
Recruiting NCT NCT06847399
Efficacy and Safety of Tirzepatide Versus Placebo or Lisdexamfetamine Dimesylate for Binge-Eating Disorder
Not yet reported Johns Hopkins University 105 participants Est. completion 2027-12-01 1 siteOther conditions: Obesity and Overweight, Binge Eating DisorderView official trial listing → -
Recruiting NCT NCT06857942
A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
Not yet reported Eli Lilly and Company 200 participants Est. completion 2028-05 39 sitesOther conditions: Psoriasis, Overweight or ObesityView official trial listing → -
Recruiting NCT NCT06888167
Food (Poly)Phenol Metabotypes and Beta-cell Mass and Function.
Not yet reported Azienda Ospedaliero-Universitaria di Parma 40 participants Est. completion 2026-02-28 1 siteOther conditions: Healthy VolunteerView official trial listing → -
Recruiting NCT NCT06894784
A Clinical Trial to Evaluate The Effects of Semaglutide and Empagliflozin Combined to Automated Insulin Delivery on Diabetes Control in Adults Living With Type 1 Diabetes
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 36 participants Est. completion 2027-01 1 siteOther conditions: Diabetes Type 1View official trial listing → -
Recruiting NCT NCT06901245
Tirzepatide in PWS, HO and GNSO
Not yet reported Grace Kim 36 participants Est. completion 2026-12 3 sitesOther conditions: Prader-Willi Syndrome, Hypothalamic Obesity, Obesity/TherapyView official trial listing → -
Recruiting NCT NCT06903923
Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy
Not yet reported University of Virginia 120 participants Est. completion 2030-04-30 1 siteOther conditions: Obesity in Children, Bone Strength, GLP - 1, Lifestyle Modification, Bone Density, ObesityView official trial listing → -
Recruiting NCT NCT06911203
A Study of BGM0504 in Participants With Obesity
Not yet reported BrightGene Bio-Medical Technology Co., Ltd. 90 participants Est. completion 2026-01-11 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT06934642
Effect of Tirzepatide on Markers of MASLD in Patients With Obesity
Not yet reported University of New Mexico 8 participants Est. completion 2026-10 1 siteMASLD Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT06937086
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Not yet reported Eli Lilly and Company 350 participants Est. completion 2028-04 187 sitesOther conditions: Ulcerative Colitis, Obesity or OverweightView official trial listing → -
Recruiting NCT NCT06937099
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Not yet reported Eli Lilly and Company 290 participants Est. completion 2028-05 183 sitesOther conditions: Crohn's Disease, Obesity or OverweightView official trial listing → -
Recruiting NCT NCT06939088
Effects of Tirzepatide on Alcohol Intake in Patients Diagnosed With Schizophrenia and Alcohol Use Disorder
Not yet reported Anders Fink-Jensen, MD, DMSci 108 participants Est. completion 2028-12-31 2 sitesAlcohol use disorder Other conditions: Alcohol Abuse/Dependence, Alcoholism, Schizophrenia Disorders, Schizophrenia and Disorders With Psychotic Features, Schizophrenia and Schizophrenia Spectrum Psychosis, SchizophreniaView official trial listing → -
Recruiting NCT NCT06976619
The Effect of Glycemic Control and of GLP-1 Receptor Agonism on Islet GLP-1 in People With Type 1 and Type 2 Diabetes
Not yet reported Mayo Clinic 60 participants Est. completion 2029-03-31 1 siteType 2 diabetes Other conditions: Type 1 DiabetesView official trial listing → -
Recruiting NCT NCT06976853
Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease
Not yet reported Washington University School of Medicine 60 participants Est. completion 2028-08 3 sitesOther conditions: Crohn Disease (CD)View official trial listing → -
Recruiting NCT NCT06994338
Tirzepatide for Alcohol Use Disorder
Not yet reported University of Southern California 42 participants Est. completion 2026-08-31 1 siteAlcohol use disorder Other conditions: Obesity and Overweight, AlcoholView official trial listing → -
Recruiting NCT NCT07012642
Efficacy of GLP-1 Receptor Agonists in Treating Upper and Lower Extremity Lymphedema
Not yet reported Advanced Reconstructive Surgery Alliance 110 participants Est. completion 2027-04-09 2 sitesOther conditions: LymphedemaView official trial listing → -
Recruiting NCT NCT07017270
Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis
Not yet reported Unity Health Toronto 100 participants Est. completion 2027-09 2 sitesOther conditions: Kidney Disease, Chronic, Diabetes, Dialysis, End Stage Kidney Disease (ESRD)View official trial listing → -
Recruiting NCT NCT07019519
POTS-FLOW: Interplay Between Gut Hormones and Autonomic Postprandial Blood Flow Regulation in Patients With POTS
Not yet reported University of Copenhagen 30 participants Est. completion 2026-09-30 1 siteOther conditions: Postural Orthostatic Tachycardia Syndrome (POTS), HealthyView official trial listing → -
Recruiting NCT NCT07027995
Food and Fitness With Medicine (FFWM)
Not yet reported Ohio State University 200 participants Est. completion 2029-03 4 sitesMetabolic syndromeType 2 diabetesView official trial listing → -
Recruiting NCT NCT07029009
Liraglutide Treatment in Patients With Maturity-onset Diabetes of the Young (MODY)
Not yet reported Mansa 50 participants Est. completion 2027-01 1 siteOther conditions: Maturity Onset Diabetes of the YoungView official trial listing → -
Recruiting NCT NCT07042672
Behavioral Therapy and GLP-1 Analogue Effects on Binge Eating, Weight, and Coping in Obesity
Haukeland University Hospital 80 participants Est. completion 2028-12-31 1 siteOther conditions: Binge Eating Disorder Associated With Obesity, Binge Eating Disorder, Eating Disorder Binge, Eating Disorders, GLP-1, CBT, Obesity &Amp; OverweightView official trial listing → -
Recruiting NCT NCT07046819
Tirzepatide in MetALD
Not yet reported National Institute on Alcohol Abuse and Alcoholism (NIAAA) 120 participants Est. completion 2027-07-30 1 siteAlcohol use disorder Other conditions: Metabolic Alcohol-associated Liver DiseaseView official trial listing → -
Recruiting NCT NCT07058155
Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease
Not yet reported The Cleveland Clinic 70 participants Est. completion 2034-02-01 1 siteOther conditions: Liver Cirrhoses, Portal Hypertension Related to Cirrhosis, Severe Obesity, TIPSView official trial listing → -
Recruiting NCT NCT07065383
Rebalancing the Fat Content of the Heart and Muscles
Not yet reported University of Aberdeen 60 participants Est. completion 2028-07-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07065552
Tirzepatide in Obesity-Driven Endometrial Cancer
Not yet reported UNC Lineberger Comprehensive Cancer Center 20 participants Est. completion 2028-07 1 siteOther conditions: Endometrial Cancer, ObesityView official trial listing → -
Recruiting NCT NCT07075341
Healthy Living BEYOND Weight Study
American Heart Association 1000000 participants Est. completion 2060-12 1 siteOther conditions: Overweight or ObesityView official trial listing → -
Recruiting NCT NCT07082062
Effects of GLP-1 Formula on GLP-1 and Glucose Regulation
Not yet reported Shih Chien Huang 100 participants Est. completion 2025-12-31 1 siteOther conditions: OverweightView official trial listing → -
Recruiting NCT NCT07082114
A Phase 3 Study to Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 800 participants Est. completion 2027-05-17 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07083154
Mazdutide in Type 2 Diabetes With Early-Stage Cognitive Impairment (LIGHT-COG Study)
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 420 participants Est. completion 2029-08-01 8 sitesType 2 diabetes Other conditions: Dementia, Mild, Mild Cognitive ImpairmentView official trial listing → -
Recruiting NCT NCT07091500
Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With Obesity
Not yet reported Washington University School of Medicine 40 participants Est. completion 2029-08-01 1 siteOther conditions: Obesity, Skeletal Muscle, Brain ConnectivityView official trial listing → -
Recruiting NCT NCT07091734
Tirzepatide for Partial Lipodystrophy Treatment: A New Horizon in 2024
Not yet reported University of Michigan 32 participants Est. completion 2029-09 1 siteOther conditions: Lipodystrophy, PartialView official trial listing → -
Recruiting NCT NCT07095517
Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2028-12-31 1 siteOther conditions: Colorectal Cancer Prevention, Colorectal AdenomaView official trial listing → -
Recruiting NCT NCT07096908
Tirzepatide Use in People With Obesity and Type 1 Diabetes
Not yet reported Dasman Diabetes Institute 60 participants Est. completion 2028-08-01 1 siteOther conditions: Type1diabetes, ObesityView official trial listing → -
Recruiting NCT NCT07101939
A Study of the Effect of (S)-Pindolol Benzoate (ACM-001.1) on Lean Body Mass (LBM) in Obese Patents During (PROACT 1), and Post-semaglutide Therapy (PROACT 2)
Not yet reported Actimed Therapeutics Ltd 120 participants Est. completion 2027-03 7 sitesOther conditions: Obesity, Muscle LossView official trial listing → -
Recruiting NCT NCT07107334
A Study to Estimate Early Clinical Efficacy Signals of GLP-1 Agonist Administration in Conjunction With Levonorgestrel Intrauterine Device in Obese Patients With Endometrioid Intraepithelial Neoplasia
Not yet reported University of Florida 20 participants Est. completion 2029-11 1 siteOther conditions: Endometrioid Endometrial AdenocarcinomaView official trial listing → -
Recruiting NCT NCT07111494
Impact of Glucagon-like Peptide-1 (GLP-1) Analogs on Disease Outcomes in Psoriatic Arthritis: A Pragmatic Randomized Controlled Trial
Not yet reported Medical College of Wisconsin 22 participants Est. completion 2028-10-15 1 siteOther conditions: Psoriatic Arthritis (PsA)View official trial listing → -
Recruiting NCT NCT07136714
Does Semaglutide Improve Depressive Symptoms in Patients With Major Depressive Disorder and Overweight or Obesity
Not yet reported Nordsjaellands Hospital 116 participants Est. completion 2027-09 1 siteOther conditions: Major Depressive DisorderView official trial listing → -
Recruiting NCT NCT07154719
GLP-1R Actions on Muscle and the Skeleton
Not yet reported Pennington Biomedical Research Center 50 participants Est. completion 2027-05-01 2 sitesOther conditions: Musculoskeletal Abnormalities, Obesity, Sarcopenic Obesity, Osteoporosis, Drug EffectView official trial listing → -
Recruiting NCT NCT07165028
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Not yet reported Eli Lilly and Company 4500 participants Est. completion 2032-08 563 sitesMASLDView official trial listing → -
Recruiting NCT NCT07169136
Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)
Nemours Children's Clinic 20 participants Est. completion 2026-12 1 siteOther conditions: Polycystic Ovarian Syndrome in Adolescent Females, Obesity (Disorder)View official trial listing → -
Recruiting NCT NCT07191873
Tirzepatide in Idiopathic Intracranial Hypertension Trial
Not yet reported Duke University 60 participants Est. completion 2028-08 1 siteOther conditions: Idiopathic Intracranial Hypertension (IIH)View official trial listing → -
Recruiting NCT NCT07193459
Study to Evaluate HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 360 participants Est. completion 2027-02-01 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07195994
A Clinical Trial to Examine the Efficacy and Safety of an Investigational Product With and Without Use of Semaglutide on Glycemic Response in Adults With Prediabetes or Type 2 Diabetes
Not yet reported QuickSilver Scientific 90 participants Est. completion 2026-09 1 siteType 2 diabetesPrediabetesView official trial listing → -
Recruiting NCT NCT07202247
Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabolic Health in Prostate Cancer Patients During Androgen Deprivation Therapy, IMPACT-ADT Trial
Not yet reported City of Hope Medical Center 60 participants Est. completion 2028-04-09 1 siteOther conditions: Prostate Carcinoma, Recurrent Prostate CarcinomaView official trial listing → -
Recruiting NCT NCT07205432
Phase I Study of XTL6001 Injection in Healthy and Obese Subjects
Not yet reported Shanghai Xitaili Biomedicine Technology co., Ltd. 80 participants Est. completion 2026-04 1 siteOther conditions: Weight Management in Adult Patients With Obesity or OverweightView official trial listing → -
Recruiting NCT NCT07207148
People With Multiple Sclerosis Treated With Ocrelizumab and GLP-1 Agonists
Northwestern University 100 participants Est. completion 2028-08-31 1 siteOther conditions: Multiple SclerosisView official trial listing → -
Recruiting NCT NCT07210684
Effects of Dihydroberberine (DHB) on GLP-1, Glycemic Control, Appetite, and Mood in Adults With Pre-Diabetes
Not yet reported Nanjing Nutrabuilding Bio-tech Co., Ltd. 54 participants Est. completion 2026-03-15 1 sitePrediabetesView official trial listing → -
Recruiting NCT NCT07212868
The Role of Glucagon in Glucose Metabolism in Humans With and Without Bariatric Surgery
Not yet reported The University of Texas Health Science Center at San Antonio 150 participants Est. completion 2030-06-30 2 sitesOther conditions: Non-DiabeticView official trial listing → -
Recruiting NCT NCT07218445
The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity
Not yet reported Mayo Clinic 40 participants Est. completion 2027-09-18 1 siteOther conditions: Obesity, Menopause Hot FlashesView official trial listing → -
Recruiting NCT NCT07220473
Tirzepatide to Slow Biological Aging
Not yet reported The University of Texas Medical Branch, Galveston 90 participants Est. completion 2028-01 1 siteOther conditions: Aging, LONGEVITY 1View official trial listing → -
Recruiting NCT NCT07224880
Ellacor® Micro-Coring Technology® in Fitzpatrick Skin Types I-VI, Including Patients Receiving Glucagon-Like Peptide-1 Receptor Agonists
Cytrellis Biosystems, Inc. 10 participants Est. completion 2026-02-28 1 siteOther conditions: glp1 Agonist, Gene Expression, Skin LaxityView official trial listing → -
Recruiting NCT NCT07225816
Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)
Not yet reported Novo Nordisk A/S 71 participants Est. completion 2027-01-06 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07228741
Resistance Exercise and Incretin Mimetic for Cardiometabolic Health in Survivors of ALL With Obesity
Not yet reported St. Jude Children's Research Hospital 20 participants Est. completion 2028-11 1 siteOther conditions: Acute Lymphoblastic Leukemia, ObesityView official trial listing → -
Recruiting NCT NCT07243171
A Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Ecnoglutide Tablets in Chinese Participants With Overweight or Obesity
Not yet reported, Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 126 participants Est. completion 2027-04-28 1 siteOther conditions: Overweight and/or Obesity, Weight ManagementView official trial listing → -
Recruiting NCT NCT07244003
Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 430 participants Est. completion 2028-06-30 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07245771
Phase 1/2a Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effect on Body Weight of RN3161 as Monotherapy and in Combination With Tirzepatide in Adults With Overweight and Obesity
Not yet reported, Not yet reported Ikaria Bioscience Pty Ltd 104 participants Est. completion 2027-08-15 1 siteOther conditions: Obesity &Amp; OverweightView official trial listing → -
Recruiting NCT NCT07246421
Glucagon Resistance in Patients With MASLD and T2DM
Not yet reported University of Aarhus 24 participants Est. completion 2028-07-31 1 siteType 2 diabetes Other conditions: Metabolic Associated Fatty Liver DiseaseView official trial listing → -
Recruiting NCT NCT07247084
A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)
Not yet reported Eli Lilly and Company 3000 participants Est. completion 2032-07 30 sitesOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07257484
Tirzepatide's Role in Postmenopausal HR+ Breast Cancer Survivors
Not yet reported Weill Medical College of Cornell University 30 participants Est. completion 2028-02-25 1 siteOther conditions: Obesity (Disorder), Breast CancerView official trial listing → -
Recruiting NCT NCT07282041
Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis
Not yet reported, Not yet reported National University of Singapore 130 participants Est. completion 2030-12-01 1 siteCardiovascular disease Other conditions: Intracranial AtherosclerosisView official trial listing → -
Recruiting NCT NCT07284511
A Clinical Trial Using Tirzepatide to Help Adults With Type 1 Diabetes Automatically Control Their Blood Sugar
Not yet reported, Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 105 participants Est. completion 2029-01 4 sitesOther conditions: Type 1 Diabetes, Type 1 Diabetes Mellitus, T1D, T1DM, T1DM - Type 1 Diabetes MellitusView official trial listing → -
Recruiting NCT NCT07284875
Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
Not yet reported Kailera 2340 participants Est. completion 2028-03 104 sitesOther conditions: Obesity, OverweightView official trial listing → -
Recruiting NCT NCT07284901
Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
Not yet reported Kailera 1156 participants Est. completion 2028-04-24 167 sitesOther conditions: Obesity With Diabetes, Overweight With DiabetesView official trial listing → -
Recruiting NCT NCT07284979
Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
Not yet reported Kailera 1200 participants Est. completion 2028-04 59 sitesOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07293325
Semaglutide and Tirzepatide for Genetic Aging Delay in Adults With Obesity
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 66 participants Est. completion 2027-06-02 1 siteOther conditions: Adults With Simple ObesityView official trial listing → -
Recruiting NCT NCT07309094
Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD
Cardenal Herrera University 250 participants Est. completion 2028-12-31 1 siteChronic kidney diseaseType 2 diabetes Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT07317115
Side-to-Side Duodeno-ileostomy Versus Semaglutide in Adults With Obesity and Type 2 Diabetes
Not yet reported GT Metabolic Solutions, Inc. 20 participants Est. completion 2028-06 1 siteType 2 diabetes Other conditions: Obesity (Disorder), Obesity & OverweightView official trial listing → -
Recruiting NCT NCT07326111
A Clincial Study Testing Tirzepatide on Reproductive Function and Metabolic Health in Women With PCOS Who Are Overweight or Obese
Not yet reported University of Bonn 198 participants Est. completion 2029-12 2 sitesOther conditions: Polycystic Ovary Syndrome (PCOS), Obesity & OverweightView official trial listing → -
Recruiting NCT NCT07327281
A Clinical Trial Evaluating TQF3250 Capsules in Healthy Adult Subjects
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 66 participants Est. completion 2026-12 1 siteOther conditions: HyperglycemiaView official trial listing → -
Recruiting NCT NCT07336862
Bariatric Surgery Combined With GLP-1 Receptor Agonists Study
Not yet reported, Not yet reported China-Japan Friendship Hospital 200 participants Est. completion 2027-12 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07364175
A Trial Within Cohort Feasibility Study Design Comparing Standard of Care Versus Weight Loss (Achieved Through Tirzepatide) for Obesity-related Hypertension in Young Adults
Not yet reported Cambridge University Hospitals NHS Foundation Trust 60 participants Est. completion 2029-01 1 siteOther conditions: Hypertension, Obesity & OverweightView official trial listing → -
Recruiting NCT NCT07373834
Tirzepatide and Muscle Outcomes in Obesity
Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2027-03 1 siteOther conditions: Obesity (Disorder)View official trial listing → -
Recruiting NCT NCT07387796
Clinical and Neurobehavioral Changes With Weight Loss Drug Discontinuation and Reinitiation
Not yet reported The University of Texas at Dallas 40 participants Est. completion 2029-02 1 siteSubstance use disorder Other conditions: Drug Discontinuation, Eating Behavior Changes, TirzepatideView official trial listing → -
Recruiting NCT NCT07398300
Insulin-Mediated Glucose Uptake and Organ Perfusion Assessed by Total-Body PET During GIP and GLP-1 Infusion
Not yet reported Copenhagen University Hospital, Rigshospitalet 36 participants Est. completion 2027-05 1 siteType 2 diabetes Other conditions: HealhtyView official trial listing → -
Recruiting NCT NCT07400783
TED_ORG: Study on Short Bowel Syndrome
Not yet reported Meyer Children's Hospital IRCCS 50 participants Est. completion 2026-10 1 siteOther conditions: Short Bowel Syndrome (SBS)View official trial listing → -
Recruiting NCT NCT07423247
Tirzepatide (Spartina) in Obese Kidney Transplant Recipients
Not yet reported Shahid Beheshti University of Medical Sciences 30 participants Est. completion 2026-09 1 siteOther conditions: TirzepatideView official trial listing → -
Recruiting NCT NCT07427251
The Postprandial Hypo-Avoid Study
Not yet reported Steno Diabetes Center Copenhagen 18 participants Est. completion 2028-05-01 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Recruiting NCT NCT07443956
Combination of Biologic and Anti-obesity Therapies in Psoriatic Arthritis
Not yet reported NHS Greater Glasgow and Clyde 45 participants Est. completion 2030-05 4 sitesOther conditions: Psoriatic Arthritis (PsA), Obesity & OverweightView official trial listing → -
Recruiting NCT NCT07444203
Transformative Research in Diabetic Nephropathy 2.0
University of Pennsylvania 200 participants Est. completion 2028-11-12 1 siteType 2 diabetes Other conditions: Diabetic Nephropathies, Kidney Diseases, Renal Insufficiency, ChronicView official trial listing → -
Recruiting NCT NCT07463846
A Study to Evaluate ALN-2232 in Participants With Obesity
Not yet reported, Not yet reported Alnylam Pharmaceuticals 156 participants Est. completion 2028-03-02 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07467447
Effect of LY3437943 Versus Placebo in Participants Who Have Obesity or Are Overweight
Not yet reported Hudson Biotech 300 participants Est. completion 2028-02-17 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07481747
Efficacy and Safety of Tirzepatide Once Weekly Versus Placebo in Participants Who Are Either Obese or Overweight With Weight-Related Comorbidities (SURMOUNT-1)
Not yet reported Hudson Biotech 2539 participants Est. completion 2028-03-17 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT07497399
Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis
Not yet reported Johns Hopkins University 120 participants Est. completion 2030-01 2 sitesOther conditions: Multiple SclerosisView official trial listing → -
Recruiting NCT NCT07521631
Efficacy and Safety of HDM1005 Compared to Tirzepatide in Obese Adults Without Diabetes
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 372 participants Est. completion 2027-07-23 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07523633
Effect of Semaglutide on Cannabis Use in Adults With Cannabis Use Disorder
Not yet reported Anders Fink-Jensen, MD, DMSci 100 participants Est. completion 2028-04-30 1 siteOther conditions: Cannabis Use Disorder, Cannabis Use Disorders, Cannabis Abuse, Cannabis Dependence, Cannabis AddictionView official trial listing → -
Recruiting NCT NCT07527910
A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD
Not yet reported Regeneron Pharmaceuticals 204 participants Est. completion 2030-03-15 9 sites Added to GLP-1MASLDView official trial listing → -
Recruiting NCT NCT07554638
Incretin Therapies in Obesity-related HFpEF
Not yet reported Columbia University 50 participants Est. completion 2030-04 1 siteHeart failure Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT07558863
Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes
Not yet reported The First Affiliated Hospital with Nanjing Medical University 60 participants Est. completion 2028-08-30 1 siteType 2 diabetes Other conditions: Diabetes With Diabetic Autonomic Neuropathy (Diagnosis)View official trial listing → -
Recruiting NCT NCT07559500
Tirzepatide s Dopaminergic Effects in Alcohol Use Disorders (AUD)
Not yet reported National Institute on Alcohol Abuse and Alcoholism (NIAAA) 176 participants Est. completion 2031-12-31 1 siteAlcohol use disorderView official trial listing → -
Recruiting NCT NCT07573163
Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion
Not yet reported Alaa Sada 34 participants Est. completion 2028-12-31 1 siteOther conditions: Mild Autonomous Cortisol Secretion (MACS), Adrenalectomy; StatusView official trial listing → -
Recruiting NCT NCT07574723
Tirzepatide Titration to Reduce Side Effects in Individuals With Obesity
Not yet reported Dasman Diabetes Institute 68 participants Est. completion 2029-12-31 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07575399
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
Not yet reported Amgen 300 participants Est. completion 2028-02-28 45 sitesOther conditions: Obesity or OverweightView official trial listing → -
Recruiting NCT NCT07588438
Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay.
Not yet reported Las Rías Medical Center 160 participants Est. completion 2027-08-10 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT07589322
Comparative Observation of Metabolic and Pharmacologic Adipose Remodeling With Enhanced Incretin AgonisTs
Not yet reported Tri-Service General Hospital (TSGH) 120 participants Est. completion 2029-09-30 1 siteMetabolic syndromeView official trial listing → -
Recruiting NCT NCT07602699
Multi-Site Trial of Tirzepatide for Smoking Cessation
Not yet reported University of Southern California 300 participants Est. completion 2028-09 4 sitesOther conditions: Smoking Cessation, Smoking BehaviorsView official trial listing → -
Recruiting NCT NCT07628127
A Trial of Oral VRB-103 Alone or in Combination With Oral Ecnoglutide (VRB-101) in Participants With Obesity or Overweight
Not yet reported Verdiva Bio Dev Limited 336 participants Est. completion 2028-03 1 siteOther conditions: Obesity, OverweightView official trial listing → -
Recruiting NCT NCT07633639
GLP-1 Therapy After Bariatric Surgery in Chinese Patients With Obesity
Not yet reported China-Japan Friendship Hospital 200 participants Est. completion 2028-05-01 1 siteOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07653412
Precision Obesity Medicine: Genetic Prediction of Response to GLP-1/GIP Agonists.
National and Kapodistrian University of Athens 220 participants Est. completion 2027-06-30 1 siteOther conditions: Obesity (Disorder), Anti-obesity Agents, Precision MedicineView official trial listing → -
Recruiting NCT NCT07685808
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
Not yet reported Regeneron Pharmaceuticals 360 participants Est. completion 2028-01-21 18 sitesOther conditions: Overweight or ObesityView official trial listing → -
Recruiting NCT NCT07702461
Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor Agonists
Ohio State University 300 participants Est. completion 2027-01 1 siteOther conditions: Obesity & Overweight, Diabetes (DM)View official trial listing → -
Recruiting NCT NCT07703683
Myokines as Potential Biomarkers and Drivers of Sarcopenia in Metabolic and Endocrine Diseases
Cliniques universitaires Saint-Luc- Université Catholique de Louvain 100 participants Est. completion 2056-12-31 1 siteOther conditions: Diabetes, Obesity & Overweight, Cushing Syndrome, Metabolic Diseases, Endocrine Diseases, Sarcopenia, Sarcopenic ObesityView official trial listing → -
Recruiting NCT NCT07704047
A Clinical Study of FT1 in Patients With Short Bowel Syndrome
Not yet reported Chongqing Peg-Bio Biopharm Co., Ltd. 8 participants Est. completion 2027-04-15 1 siteOther conditions: Short Bowel Syndrome, SBSView official trial listing → -
Recruiting NCT NCT07723833
A Study to Investigate the Relative Bioavailability and Safety of Different Oral Formulations of Elecoglipron in Healthy Participants
Not yet reported AstraZeneca 152 participants Est. completion 2026-11-18 2 sitesOther conditions: Healthy ParticipantsView official trial listing → -
Recruiting NCT NCT07732738
Bariatric Surgery Combined With GLP-1RA: A Multicenter Study.
Not yet reported China-Japan Friendship Hospital 400 participants Est. completion 2027-12-30 7 sitesOther conditions: ObesityView official trial listing → -
Recruiting NCT NCT07734870
Tirzepatide for Treatment of CCCA
Not yet reported Johns Hopkins University 20 participants Est. completion 2028-05-25 2 sitesOther conditions: Central Centrifugal Cicatricial Alopecia (CCCA)View official trial listing → -
Recruiting NCT NCT07742735
A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
Not yet reported VectivBio AG 124 participants Est. completion 2029-10 94 sitesOther conditions: Short Bowel Syndrome (SBS), SBS Associated With Intestinal Failure (SBS-IF)View official trial listing → -
Recruiting NCT NCT07743567
Gestational Response, Outcomes, and Weight After GLP-1 Use
University of Kansas Medical Center 400 participants Est. completion 2028-04 1 siteOther conditions: Pregnant Individuals, Obesity & Overweight, Gestational Weight GainView official trial listing → -
Recruiting NCT NCT07747857
A Clinical Trial Evaluating TQF3250 Capsules in Patients With Type 2 Diabetes Mellitus and Overweight/Obesity
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 72 participants Est. completion 2027-07 12 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT07773272
Cardiovascular-kidney-metabolic (CKM)-Guided Therapy for Patients After Acute Coronary Syndrome
Zuyderland Medisch Centrum 1215 participants Est. completion 2029-03-31 1 siteOther conditions: Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI), Hypercholerolemia, Hypertension, Diabete Mellitus, Cardiovascular Risk ManagementView official trial listing → -
Recruiting NCT NCT07789223
Weight and Metabolic Management Study
Not yet reported Elenzia 200 participants Est. completion 2027-02 1 siteOther conditions: Overweight, Obesity, Weight MaintenanceView official trial listing → -
Recruiting NCT NCT07793929
A Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics (PK) of Ribupatide
Not yet reported Kailera 32 participants Est. completion 2028-02-08 2 sitesOther conditions: End Stage Renal Disease, Renal Impairment, Obesity, OverweightView official trial listing → -
Recruiting NCT NCT07795736
Charactertizing Growth Hormone Deficiency in Traumatic Brain Injury
University of Calgary 200 participants Est. completion 2028-11-01 2 sitesOther conditions: Growth Hormone Deficiency, Traumatic Brain InjuryView official trial listing → -
Recruiting NCT NCT07803185
Evaluation of Anhedonia and Emotional Eating in Individuals Using GLP-1 Receptor Agonists
TC Erciyes University 60 participants Est. completion 2026-12-31 1 siteOther conditions: Obesity, Emotional Eating, AnhedoniaView official trial listing → -
Recruiting NCT NCT07803744
A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity
Not yet reported Eli Lilly and Company 18 participants Est. completion 2026-12 1 siteOther conditions: Diabetes Mellitus, Type 1, Overweight, ObesityView official trial listing → -
Recruiting NCT NCT07818707
Post-Prandial Carbohydrate Metabolism in Individuals With and Without Post-Bariatric Surgery Hypoglycemia (PBH)
Not yet reported Joslin Diabetes Center 40 participants Est. completion 2027-01 2 sitesOther conditions: Hypoglycemia, Hypoglycemia, Reactive, Bariatric SurgeryView official trial listing → -
Recruiting NCT NCT07842640
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASC35 Injection in Participants With Obesity or Overweight
Not yet reported Ascletis Pharma (China) Co., Limited 84 participants Est. completion 2027-06 1 siteOther conditions: Chronic Weight ManagementView official trial listing → -
Completed NCT NCT00001229
Diagnosis and Treatment of Pheochromocytoma
National Heart, Lung, and Blood Institute (NHLBI) 240 participants Est. completion 2001-01 1 siteOther conditions: PheochromocytomaView official trial listing → -
Status unknown NCT NCT00005889
Gluconeogenesis in Very Low Birth Weight Infants Who Are Receiving Nutrition By Intravenous Infusion
Not yet reported National Center for Research Resources (NCRR) 96 participants 1 siteOther conditions: Infant, Low Birth Weight, HyperglycemiaView official trial listing → -
Completed NCT NCT00013910
NNC 90-1170 Mechanism of Action: A Double-Blind, Randomized, Single-Center, Placebo-Controlled, Crossover Study to Examine Beta-Cell Responsiveness to Graded Glucose Infusion in Subjects With Type 2 Diabetes
Not yet reported National Center for Research Resources (NCRR) 30 participants 1 siteOther conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT00105352
Improving Metabolic Assessments in Type 1 Diabetes Mellitus Clinical Trials
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 120 participants Est. completion 2005-11 18 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT00145353
Insulin NovoRapid Versus Actrapid in Treatment of Type 1 Diabetic Patients During Daily Adjustment of Insulin Dose
Not yet reported Odense University Hospital 16 participants Est. completion 2006-06 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00154401
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 177 participants Est. completion 2005-10 39 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00154414
Effect of Liraglutide on Blood Glucose Control in Japanese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 226 participants Est. completion 2006-05 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT00155376
Intravenous-Morphine and Glucagon-Usage Enhanced MR Cholangiography
Not yet reported National Taiwan University Hospital 100 participants Est. completion 2005-09 1 siteOther conditions: Liver DiseaseView official trial listing → -
Completed NCT NCT00180648
Plasma Determination of Glucagon-like Peptide 2 as a Predictor of Recovery in Adults With Acute Intestinal Failure
Imperial College London 30 participants Est. completion 2008-02Other conditions: Short Bowel SyndromeView official trial listing → -
Completed NCT NCT00206258
The Role of Amylin and Glucagon in T1DM
Not yet reported Baylor College of Medicine 30 participants Est. completion 2005-08 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00230464
Acute Metabolic Effects of LAF 237 in Type 2 Diabetics
Not yet reported The University of Texas Health Science Center at San Antonio 16 participants Est. completion 2005-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00256256
The Effect of GLP-1 on Glucose Uptake in the Brain and Heart in Healthy Men
Not yet reported University of Aarhus 10 participants Est. completion 2007-01 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00259727
The Study of HIV Protease Inhibitors and Their Effects on Glucose Metabolism
US Department of Veterans Affairs 80 participants Est. completion 2008-09 1 siteOther conditions: Diabetes, HIV Infections, Insulin ResistanceView official trial listing → -
Completed NCT NCT00264199
Effect of 48 Hours of Treatment With the Natural Peptide-Hormone GLP-1 in Patients With Chronic Heart Failure
Not yet reported Aarhus University Hospital Skejby 20 participants Est. completion 2007-12 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT00273000
The Importance of Glucagon-Like Peptide-2 (GLP-2)in Mesenteric Bloodflow in Humans
Not yet reported Glostrup University Hospital, Copenhagen 10 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00285896
GLP-1 Infusion and Long-Time Fasting
Not yet reported University of Aarhus 8 participants Est. completion 2007-05 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00294723
To Evaluate the Effect of Liraglutide Versus Glimepiride (Amaryl®) on Haemoglobin A1c
Not yet reported Novo Nordisk A/S 746 participants Est. completion 2008-11 117 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00304538
A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Very Low Dose-Glucagon in Subjects With Type 1 Diabetes Mellitus
Not yet reported DiObex 10 participants Est. completion 2006-07 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00318422
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1041 participants Est. completion 2007-05 127 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00318461
To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together
Not yet reported Novo Nordisk A/S 1091 participants Est. completion 2008-11 190 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00331851
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 584 participants Est. completion 2007-04 116 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00333151
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 576 participants Est. completion 2007-08 89 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00353834
The Effect of Exenatide Compared to Lantus Insulin on Vascular Function in Type 2 Diabetes
Not yet reported Joslin Diabetes Center 72 participants Est. completion 2010-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00390520
Efficacy and Safety of Vildagliptin Versus Placebo in Patients With Type 2 Diabetes
Not yet reported Novartis 28 participants Est. completion 2007-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00393445
Exendin(9-39)Amide as a Glucagon-like Peptide-1 (GLP-1) Receptor Antagonist in Humans
Not yet reported Ludwig-Maximilians - University of Munich 6 participants Est. completion 2007-05 1 siteOther conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT00393718
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 400 participants Est. completion 2008-05 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00395746
Effect of Liraglutide in Combination With Sulfonylurea (SU) on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 264 participants Est. completion 2008-05 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00418288
The Effect of GLP-1 on Glucose Uptake in the Brain and Heart in Healthy Men During Hypoglycemia
Not yet reported University of Aarhus 10 participants Est. completion 2008-02 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT00422058
The Effect of Liraglutide on Body Weight in Obese Subjects Without Diabetes
Not yet reported Novo Nordisk A/S 564 participants Est. completion 2009-04-30 19 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT00434772
Glucagon in the Treatment of Hypoglycemia in Newborn Infants of Diabetic Mothers
Not yet reported Shaare Zedek Medical Center Est. completion 2009-05 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT00460941
A Titration Study of a Glucagon-Like Peptide-1 (GLP-1) Analogue in Patients With Type 2 Diabetes Treated With Metformin.
Not yet reported Hoffmann-La Roche 133 participants Est. completion 2008-01 29 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT00473733
Glucagon Like Peptides Receptors Expression in the Stomach of Diabetes Type 2
Not yet reported Assaf-Harofeh Medical Center 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00488423
Glucose Metabolism in the Immediate and Short Term Follow up After Bariatric Surgery
Not yet reported The Cleveland Clinic 21 participants Est. completion 2008-11 1 siteOther conditions: Diabetes, Gastric BypassView official trial listing → -
Completed NCT NCT00515801
Sulfonylurea Effects on Glucagon Regulation During Hypoglycemia in Type 1 DM
Not yet reported, Not yet reported University Hospital, Basel, Switzerland 18 participants 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00518882
Effect of Liraglutide or Exenatide Added to an Ongoing Treatment on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 467 participants Est. completion 2009-04 125 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00529048
Quantification of the Incretin Effect in Healthy Subjects and Patients With Type 2 Diabetes
Herlev Hospital 16 participants Est. completion 2009-09 1 siteOther conditions: Incretin EffectView official trial listing → -
Completed NCT NCT00537719
Scintigraphy Study to Assess Gastric Emptying in Healthy Subjects Given GSK716155 or Placebo.
Not yet reported GlaxoSmithKline 34 participants Est. completion 2008-04-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00566189
New Frontiers on Bariatric Surgical Procedures: Classical Bypass for Type-2 Diabetic Patients With Obesity Grade I
Not yet reported, Not yet reported University of Campinas, Brazil 36 participants Est. completion 2012-12 1 siteType 2 diabetes Other conditions: Insulin Resistance, ObesityView official trial listing → -
Terminated NCT NCT00566215
Treatment of Type 2 Diabetes Mellitus by Duodenal Exclusion Associated With Omentectomy: Clinical and Hormonal Study
Not yet reported, Not yet reported University of Campinas, Brazil 6 participants Est. completion 2009-06 1 siteType 2 diabetes Other conditions: Insulin Resistance, ObesityView official trial listing → -
Completed NCT NCT00566358
Surgical Treatment of Non-obese Type 2 Diabetic Patients With Duodenal Exclusion
Not yet reported, Not yet reported University of Campinas, Brazil 18 participants Est. completion 2009-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00571324
Effect of Exendin-(9-39) on Glycemic Control in Subjects With Congenital Hyperinsulinism
Not yet reported, Not yet reported Diva De Leon 9 participants Est. completion 2014-12 1 siteOther conditions: Congenital HyperinsulinismView official trial listing → -
Completed NCT NCT00588380
GLP1R Polymorphisms and Response to GLP1
Not yet reported Mayo Clinic 88 participants Est. completion 2010-09 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00603031
Effect of GLP-1 and GIP on Insulin Secretion in Type-1 Diabetes Mellitus
Not yet reported Hvidovre University Hospital 9 participants Est. completion 2008-06 1 siteOther conditions: Type-1 Diabetes MellitusView official trial listing → -
Terminated NCT NCT00609154
Effect of GLP-1 on Insulin Biosynthesis and Turnover Rates
Not yet reported, Not yet reported Albert Einstein College of Medicine 20 participants Est. completion 2014-05-13 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00612625
Near Normalisation of BG Improves the Potentiating Effect of GLP-1
Not yet reported Hvidovre University Hospital 9 participants Est. completion 2004-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00612950
Beta-Cell Function After Near-Normalisation of Blood Glucose
Not yet reported Hvidovre University Hospital 8 participants Est. completion 2007-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00614120
Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 929 participants Est. completion 2009-02 50 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00620282
The Effect of Liraglutide on Endothelial Function in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 49 participants Est. completion 2010-05 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT00625040
Incretin Physiology and Beta-cell Function Before and After Weight-loss
Glostrup University Hospital, Copenhagen 10 participants Est. completion 2011-01 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT00633763
PET-CT Scan Method to Monitor Pancreatic B-Cell Loss in Diabetes Mellitus
University of California, Irvine 30 participants Est. completion 2008-07 1 siteOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT00639613
The Role of Small Intestinal Endocrine Cells in Type 2 Diabetic Hyperglucagonemia
University Hospital, Gentofte, Copenhagen 20 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00651105
Effect of LAF237 on Glucagon Secretion in Patients With Type 2 Diabetes and in Healthy Subjects
Not yet reported Novartis 63 participants 2 sitesOther conditions: Type-2 Diabetes, HealthyView official trial listing → -
Status unknown NCT NCT00655603
Influence of Glucagon Inhibition in Relation to the Anti-Diabetic Effect of Glucagon-Like Peptide-1 (GLP-1) in Patients With Type 2 Diabetes Mellitus
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2009-09Type 2 diabetesView official trial listing → -
Status unknown NCT NCT00673751
Effect of the Enteric Hormone Glucagon-Like Peptide (GLP-2) on the Intestinal Blood Flow in Patients With Short Bowel Syndrome
Not yet reported Glostrup University Hospital, Copenhagen 8 participants 1 siteOther conditions: Short Bowel SyndromeView official trial listing → -
Completed NCT NCT00673894
Effects of Glutamine on GLP-1 and Insulin Secretion in Man
Not yet reported Garvan Institute of Medical Research 22 participants Est. completion 2014-11 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00686972
The Effect of Surgically Induced Weight Loss on Endocrine Function, Cardiovascular Function and Body Composition
Not yet reported Johns Hopkins University 51 participants Est. completion 2010-10 1 siteOther conditions: Bariatric SurgeryView official trial listing → -
Completed NCT NCT00694122
Comparison of Lantus and Neutral Protamine Hagedorn (NPH) Insulin in the Dawn Phenomenon
Not yet reported Massachusetts General Hospital 27 participants Est. completion 2010-11 1 siteOther conditions: Type 1 Diabetes, Dawn PhenomenonView official trial listing → -
Completed NCT NCT00696657
A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and Liraglutide
Not yet reported Novo Nordisk A/S 415 participants Est. completion 2009-02-05 77 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00700817
The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 665 participants Est. completion 2010-06 166 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT00704795
Glucagon Responses During Oral- and iv Glucose in Patients With Type 1 Diabetes
University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2009-10 1 siteOther conditions: Hyperglucagonemia, Hyperglycemia, Diabetes MellitusView official trial listing → -
Completed NCT NCT00713440
Incretin Physiology Associated With Steroid Hormone Treatment
Not yet reported Glostrup University Hospital, Copenhagen 10 participants Est. completion 2009-01 1 siteType 2 diabetes Other conditions: SteroidsView official trial listing → -
Completed NCT NCT00716170
GIP, GLP-1 and GLP-2 in Type 2 Diabetic Hyperglucagonemia
Herlev Hospital 10 participants Est. completion 2009-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00732602
The Effects of GIP and GLP-2 on the Secretion of Glucagon in Patients With Type 1 Diabetes
Not yet reported University Hospital, Gentofte, Copenhagen 8 participants 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT00740012
Glycemic Rises After Waking Up In Response To An Alarm Clock In Type 1-Diabetic Patients Analysed With Continuous Glucose Monitoring (GlucoDay®)
Not yet reported Diabeteszentrum Bad Lauterberg im Harz 32 participants Est. completion 2008-09 1 siteOther conditions: Stress, Type 1 DiabetesView official trial listing → -
Completed NCT NCT00740324
Exploratory Study of Additional Use of Scopolamine Butylbromide, Glucagon or NPO-11 Following Single Dose of NPO-11 in Healthy Adult Men
Not yet reported Nihon Pharmaceutical Co., Ltd 30 participants Est. completion 2009-07 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00745186
Pharmacokinetics (PK) and Pharmacodynamics (PD) of Mayne Glucagon for Injection Compared With Glucagen® (Novo Nordisk) in Healthy Volunteers
Not yet reported Hospira, now a wholly owned subsidiary of Pfizer 28 participants Est. completion 2008-03 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT00747383
How Improvement in Control of Diabetes Influences the Production of a Hormone Produced in the Gut Which Improves the Release and Action of Insulin.
Not yet reported The Royal Bournemouth Hospital 74 participants Est. completion 2010-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00761540
To Investigate the Blood Concentration of Liraglutide as Well as the Effects on Glucose and Insulin After 21 Days of Daily Subcutaneous Injections of Liraglutide or Placebo
Not yet reported Novo Nordisk A/S 37 participants Est. completion 2008-12 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT00775684
Effect of Exenatide, Sitagliptin or Glimepiride on Functional ß -Cell Mass
Not yet reported University of Pennsylvania 47 participants Est. completion 2012-11 3 sitesPrediabetesType 2 diabetesView official trial listing → -
Completed NCT NCT00781937
Comparison of Liraglutide Versus Placebo in Weight Loss Maintenance in Obese Subjects: SCALE - Maintenance
Not yet reported Novo Nordisk A/S 422 participants Est. completion 2010-09-01 37 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT00797823
Sensor-Augmented Insulin Delivery: Insulin Plus Glucagon Versus Insulin Alone
Not yet reported Legacy Health System 14 participants Est. completion 2009-09 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Terminated NCT NCT00798590
The Efficacy of Glucagon Like Peptide (GLP) - 1(7-36) Amide for Glycemic Control in Critically Ill Patients
Not yet reported Johns Hopkins University 19 participants Est. completion 2011-06 1 siteOther conditions: Critically Ill, HypoglycemiaView official trial listing → -
Terminated NCT NCT00799435
Evaluating the Use of Exenatide in People With Type 2 Diabetes and Diastolic Heart Failure
Not yet reported Baylor College of Medicine 2 participants Est. completion 2012-04 1 siteType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT00807729
Randomized Trial of ERCP Then Laparoscopic Cholecystectomy vs. Laparoscopic Cholecystectomy Plus Laparoscopic Common Bile Duct Exploration in Patients With Likely Choledocholithiasis
Not yet reported University of California, San Francisco 122 participants Est. completion 2007-11 1 siteOther conditions: Choleclithiasis, Common Bile Duct StonesView official trial listing → -
Completed NCT NCT00811317
Closed-loop Glucose Control for Automated Management of Type 1 Diabetes
Not yet reported Boston University Charles River Campus 11 participants Est. completion 2009-10 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT00817271
To Evaluate the Response to Glucagon During Hypoglycemia
Not yet reported AstraZeneca 8 participants Est. completion 2009-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00823940
A Phase 1 Study to Evaluate the Safety and Tolerability of GSK1362885 in Healthy Normal Subjects
Not yet reported GlaxoSmithKline 42 participants Est. completion 2009-04-27 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00829569
n-3 Fatty Acid Infusion and Type 2 Diabetes
Not yet reported St. Olavs Hospital 11 participants Est. completion 2008-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00834938
Comparison Between Patients With or Without Diabetes Recovery After Bariatric Surgery
University of Campinas, Brazil 24 participants Est. completion 2010-07 1 siteOther conditions: Diabetes, Bariatric Surgery, ObesityView official trial listing → -
Terminated NCT NCT00835328
Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia
Not yet reported, Not yet reported Diva De Leon 14 participants Est. completion 2017-01-28 1 siteOther conditions: Congenital HyperinsulinismView official trial listing → -
Completed NCT NCT00843232
Characterization of the Incretinpathy in Type 2 Diabetes Initiated After Sixty Years Old
University of Campinas, Brazil 24 participants Est. completion 2010-09 1 siteType 2 diabetes Other conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT00843479
The Aging Endocrine Pancreas: Characterization of the Entero-insular Axis Physiology in the Elderly
University of Campinas, Brazil 24 participants Est. completion 2010-09 1 siteType 2 diabetes Other conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT00847080
Treatment With Sitagliptin for Reactive Hypoglycemia Secondary to Dysinsulinism
Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 20 participants Est. completion 2011-03 1 siteOther conditions: Reactive HypoglycemiaView official trial listing → -
Terminated NCT NCT00853944
Effect of Sitagliptin on Graft Function Following Islet Transplantation
Not yet reported University of British Columbia 12 participants Est. completion 2013-11-01 1 siteOther conditions: Islet TransplantationView official trial listing → -
Completed NCT NCT00856700
Glucagon-like Peptide 1 (GLP-1) and Endothelial Dysfunction in Metabolic Syndrome
Not yet reported University of Rome Tor Vergata 20 participants Est. completion 2012-06 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT00856986
The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 987 participants Est. completion 2010-11 233 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00859079
Efficacy of GLP-1 Infusion in Comparison to an Insulin Infusion Protocol to Reach Normoglycemia Type 2 Diabetic Patients
Not yet reported Medical University of Graz 8 participants Est. completion 2007-01 1 siteType 2 diabetes Other conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT00862589
Glucagon-Like Peptide-1 (GLP-1) Suppression of Alpha Cell Secretion in Type 2 Diabetes Mellitus (T2DM)
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2007-03Other conditions: Hyperglycemia, Hyperglucagonemia, Glucose IntoleranceView official trial listing → -
Withdrawn NCT NCT00869102
Characterization of Beta Cell Failure
Not yet reported University Hospital Tuebingen Est. completion 2011-12 1 siteMetabolic syndrome Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00873223
Examination of the Effects of Liraglutide on the Mode of Action of Insulin Detemir
Not yet reported Novo Nordisk A/S 33 participants Est. completion 2009-09 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00876213
Amylin and Glucagon-Like Peptide-1 (GLP-1): Influence on Gastric Emptying, Appetite and Food Intake in Humans
Hvidovre University Hospital 23 participants Est. completion 2008-06 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00881543
"Effect of Dipeptidyl Peptidase IV After Diets in näive Type 2 Diabetic Patients"
Not yet reported University of Sao Paulo General Hospital 45 participants Est. completion 2011-10 1 siteOther conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT00882050
Intravenous Exenatide (Byetta) During Surgery
Not yet reported, Not yet reported Thomas Jefferson University 104 participants Est. completion 2016-04 1 siteOther conditions: Euglycemia, Hypoglycemia, HyperglycemiaView official trial listing → -
Completed NCT NCT00882492
GLP 1 for Intraoperative Glycemic Control
Not yet reported University of Pennsylvania 80 participants Est. completion 2011-05 1 siteOther conditions: Hyperglycemia, HypoglycemiaView official trial listing → -
Completed NCT NCT00884091
A Pilot Study to Evaluate the Glucagon-Like Peptide 1 Response to the Challenge of Mixed Meals in Chinese Subjects
Taipei Veterans General Hospital, Taiwan 21 participants Est. completion 2011-07 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00897676
Effect of Exendin-(9-39) on Fasting Adaptation and Protein Sensitivity
Not yet reported, Not yet reported Diva De Leon 17 participants Est. completion 2017-01 1 siteOther conditions: Congenital HyperinsulinismView official trial listing → -
Completed NCT NCT00923962
Endothelial and Metabolic Effects of Glucagon-like Peptide-1 (GLP-1) in Coronary Circulation in Patients With Type 2 Diabetes Mellitus
Not yet reported University Hospital, Gentofte, Copenhagen 35 participants Est. completion 2012-01 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT00929812
Glucagon Modulation of Ghrelin Secretion
Not yet reported Charite University, Berlin, Germany 38 participants Est. completion 2009-12 1 siteOther conditions: Healthy Subjects, Obesity, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT00937079
Whole Body 111In-exendin-4 Imaging Study in Insulinoma Patients
University Hospital, Basel, Switzerland 30 participants Est. completion 2011-12 1 siteOther conditions: Hyperinsulinism, Hypoglycemia, InsulinomaView official trial listing → -
Completed NCT NCT00940134
Effects of Intravenous Infusions of Gut Hormones on Appetite and Metabolism.
Not yet reported University of Copenhagen 24 participants Est. completion 2012-01 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT00943501
Safety of Liraglutide in Pediatric Patients With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 21 participants Est. completion 2011-09 20 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT00947011
Dipeptidyl Peptidase-4 Inhibition on Glucagon-like Peptide-1 (GLP-1)
Not yet reported Johns Hopkins University 12 participants Est. completion 2010-03 1 siteOther conditions: Glucose HomeostasisView official trial listing → -
Completed NCT NCT00950677
The Effect of Byetta and Symlin on Post-meal Meal Blood Sugar Levels in Children With Type 2 Diabetes
Not yet reported Baylor College of Medicine 16 participants Est. completion 2011-05 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT00966654
Effect of GLP - 1 (7-36 Amide) on Myocardial Function Following Coronary Artery Bypass (CABG) Surgery
Not yet reported Johns Hopkins University 12 participants Est. completion 2012-09 1 siteOther conditions: CABGView official trial listing → -
Completed NCT NCT00969566
Predictive Parameters for Efficacy of Sitagliptin and Metformin Combination
Not yet reported Seoul National University Bundang Hospital 150 participants Est. completion 2011-07 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00978393
A Trial to Assess the Effect of Liraglutide on Gastric Emptying in Healthy Obese Volunteers
Not yet reported Novo Nordisk A/S 49 participants Est. completion 2011-06-08 1 siteOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT00980083
GLP-1 - Regulatory Mechanism of Postprandial Glycemia
Not yet reported Ludwig-Maximilians - University of Munich 12 participants Est. completion 2007-12 1 siteOther conditions: Healthy Subjects, Gastric EmptyingView official trial listing → -
Completed NCT NCT00983021
Safety and Tolerability of NN9068 in Healthy Male Volunteers
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2009-12 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT00993304
A Trial to Assess the Effect of Liraglutide on Blood Triglyceride (Fat) Levels After a Meal in Type 2 Diabetics
Not yet reported Novo Nordisk A/S 20 participants Est. completion 2010-12 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT00993720
Effect of GLP-1 on Insulin-dose, Risk of Hypoglycemia and Gastric Emptying Rate in Patients With Type 1 Diabetes
Not yet reported, Not yet reported Hvidovre University Hospital 30 participants Est. completion 2010-10 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01021865
Effects of Hyperglycemia on Myocardial Perfusion in Humans With and Without Type 2 Diabetes
Mayo Clinic 33 participants Est. completion 2014-07 1 siteCardiovascular diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT01029886
Safety and Efficacy of Exenatide Once Weekly Versus Liraglutide in Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 912 participants Est. completion 2011-04 108 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01056107
Effects of ROSE-010 on GI Transit in Constipation Predominant Irritable Bowel Syndrome (C-IBS) Patients
Not yet reported, Not yet reported Mayo Clinic 52 participants Est. completion 2011-12 1 siteOther conditions: Irritable Bowel Syndrome Constipation PredominantView official trial listing → -
Completed NCT NCT01065298
Efficacy Of Autologous Bone Marrow Derived Stem Cell Transplantation In Patients With Type 2 Diabetes Mellitus-2
Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2011-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01079624
GIP and GLP-1 on Gastric Emptying, Appetite and Insulin-glucose
Not yet reported Uppsala University 15 participants Est. completion 2009-11 1 siteOther conditions: Physiology, Gastroenterology, EndocrinologyView official trial listing → -
Completed NCT NCT01079715
Safety and Efficacy of Propranolol in Newborns With Retinopathy of Prematurity
Not yet reported, Not yet reported Meyer Children's Hospital IRCCS 52 participants Est. completion 2012-10 2 sitesOther conditions: Retinopathy of PrematurityView official trial listing → -
Completed NCT NCT01088841
Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY
Not yet reported University Hospital, Basel, Switzerland 16 participants Est. completion 2010-03 1 siteOther conditions: Appetite and General Nutritional Disorders, Hormone ReplacementView official trial listing → -
Completed NCT NCT01117350
Efficacy Assessment of Insulin Glargine Versus LiraglutidE After Oral Agents Failure
Not yet reported Sanofi 978 participants Est. completion 2013-03 136 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01128894
A Study to Determine the Efficacy and Safety of Albiglutide as Compared With Liraglutide.
Not yet reported GlaxoSmithKline 841 participants Est. completion 2011-09 173 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01147276
Vildagliptin and the Glucagon Response to Hypoglycemia in Type 1 Diabetes
Not yet reported Lund University 28 participants Est. completion 2011-12 1 siteOther conditions: Diabetes, HypoglycemiaView official trial listing → -
Completed NCT NCT01153438
Relationship Between Changes in Gut Hormones After Gastric Bypass and Gastric Banding and Improvements in Diabetes
University of Pennsylvania 8 participants Est. completion 2013-06 1 siteType 2 diabetes Other conditions: Obesity, Bariatric SurgeryView official trial listing → -
Completed NCT NCT01155206
Acute Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon
Not yet reported University Health Network, Toronto 9 participants Est. completion 2010-01 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01161862
Integration of Continuous Glucose Monitoring Into a BiHormonal Closed-Loop Artificial Pancreas
Not yet reported Boston University Charles River Campus 24 participants Est. completion 2013-06 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01162499
Role of Glucagon-Like Peptide-1 in Postprandial Hypoglycemia
Not yet reported Diva De Leon 7 participants Est. completion 2014-12 1 siteOther conditions: Postprandial HypoglycemiaView official trial listing → -
Completed NCT NCT01173978
Insulinotropic Effect of GIP and GLP-1 Before and After Reduced Glucose Tolerance
Not yet reported Glostrup University Hospital, Copenhagen 10 participants Est. completion 2010-07 1 siteOther conditions: Insulin Resistance, Deteriorated Glucose Homeostasis, InactivityView official trial listing → -
Completed NCT NCT01175473
Effects of Lixisenatide Compared to Liraglutide on the Postprandial Plasma Glucose in Patients With Type 2 Diabetes
Not yet reported Sanofi 148 participants Est. completion 2010-11 7 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01176708
Intact Liver Innervation and Glucose and Glucagon-like Peptide-1 (GLP-1) Induced Insulin Secretion
Not yet reported University Hospital, Gentofte, Copenhagen 30 participants Est. completion 2012-12 1 siteOther conditions: Liver TransplantationView official trial listing → -
Status unknown NCT NCT01176760
Intact Vagal Innervation for and Glucagon-like Peptide-1 (GLP-1) Effects
Not yet reported University Hospital, Gentofte, Copenhagen 30 participants Est. completion 2012-12 1 siteOther conditions: Vagotomy, TruncalView official trial listing → -
Status unknown NCT NCT01176890
Intact Vagal Innervation and Glucagon-like Peptide-1 (GLP-1) Effects
Not yet reported University Hospital, Gentofte, Copenhagen 30 participants Est. completion 2012-12 1 siteOther conditions: Vagotomy, TruncalView official trial listing → -
Completed NCT NCT01179048
Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results
Not yet reported Novo Nordisk A/S 9341 participants Est. completion 2015-12-17 428 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01185119
Effect of GLP-1 on Glucose Metabolism in CNS Assessed by PET
Not yet reported, Not yet reported University of Aarhus 10 participants Est. completion 2011-03 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01189890
Safety and Efficacy of Sitagliptin Compared With Glimepiride in Elderly Participants With Type 2 Diabetes Mellitus (MK-0431-251)
Not yet reported Merck Sharp & Dohme LLC 480 participants Est. completion 2012-10-31Type 2 diabetesView official trial listing → -
Terminated NCT NCT01206101
Efficacy and Safety of Liraglutide in Subjects With Type 1 Diabetes Undergoing Islet Cell Transplantation
Not yet reported Novo Nordisk A/S 3 participants Est. completion 2013-06-03 16 sitesOther conditions: Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01208012
Impact of Liraglutide on Endothelial Function and Microvascular Blood Flow in Type 2 Diabetes Mellitus
Not yet reported ikfe-CRO GmbH 44 participants Est. completion 2010-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01212133
A Post Marketing Surveillance (PMS) Study of Liraglutide in Subjects With Type 2 Diabetes Mellitus in India
Novo Nordisk A/S 1386 participants Est. completion 2012-04 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01218633
Dose-response Study of Exendin-9,39 on Glucose Metabolism
Not yet reported Adrian Vella 11 participants Est. completion 2012-12 1 siteOther conditions: Pancreatic Effects of 9,39-Exendin and 9,36-GLP-1View official trial listing → -
Completed NCT NCT01219400
Vildagliptin and the Glucagon Response to Hypoglycemia in Insulin-Treated Patients With Type 2 Diabetes
Not yet reported Lund University 28 participants Est. completion 2013-12 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01226966
Observational Study on Efficacy and Safety of Liraglutide in Subjects With Type 2 Diabetes
Novo Nordisk A/S 3152 participants Est. completion 2013-11 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01232244
Oxyntomodulin, Mechanisms of Action in Relation to Appetite, Food Intake, Gastric Emptying and Energy Expenditure.
University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2012-01 1 siteOther conditions: Incretin Action, ObesityView official trial listing → -
Completed NCT NCT01232946
Cooperation of Insulin and GLP-1 on Myocardial Glucose Uptake
Not yet reported Indiana University 30 participants Est. completion 2017-09-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01234649
Combined Liraglutide and Metformin Therapy in Women With Previous Gestational Diabetes Mellitus (GDM)
Not yet reported Woman's 153 participants Est. completion 2019-06-14 1 siteType 2 diabetesMetabolic syndromePrediabetes Other conditions: Gestational Diabetes Mellitus, Disorder of Glucose RegulationView official trial listing → -
Completed NCT NCT01237119
Liraglutide Efficacy and Action in Non-Alcoholic Steatohepatitis
Not yet reported University of Birmingham 52 participants Est. completion 2014-07 1 siteMASHView official trial listing → -
Status unknown NCT NCT01254123
Effect of Additional Treatment With EXenatide in Patients With an Acute Myocardial Infarction (the EXAMI Trial)
Not yet reported Amsterdam UMC, location VUmc 40 participants 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01261052
Real-time Adaptation to Changes in Insulin Sensitivity
Not yet reported Legacy Health System 14 participants Est. completion 2011-04 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01270789
LIraglutide and Beta-cell RepAir (LIBRA) Study
Not yet reported Mount Sinai Hospital, Canada 63 participants Est. completion 2014-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01272219
Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes
Not yet reported Novo Nordisk A/S 3731 participants Est. completion 2015-03-02 226 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT01272232
Effect of Liraglutide on Body Weight in Overweight or Obese Subjects With Type 2 Diabetes: SCALE™ - Diabetes
Not yet reported Novo Nordisk A/S 846 participants Est. completion 2013-01-25 161 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT01272583
Dipeptidyl Peptidase-4 Inhibitors and Alpha-cell Recovery
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 16 participants Est. completion 2012-10 1 siteOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Completed NCT NCT01274052
Study of Postprandial Incretin Response in Women With Gestational Diabetes
University Hospital, Gentofte, Copenhagen 19 participants Est. completion 2008-07 1 siteOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT01282164
The Glucagon Stimulation Test for Evaluation of Adult Growth Hormone Deficiency and Adrenocorticotropic Axis
Not yet reported The Cleveland Clinic 43 participants Est. completion 2014-07 4 sitesOther conditions: Adult Growth Hormone Deficiency, Hypothalamic-pituitary DisordersView official trial listing → -
Completed NCT NCT01288326
Observational Study on Effectiveness and Safety of Liraglutide in Subjects With Type 2 Diabetes
Novo Nordisk A/S 254 participants Est. completion 2013-03 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01296412
Comparison of Two Treatment Regimens (Sitagliptin Versus Liraglutide) on Participants Who Failed to Achieve Good Glucose Control on Metformin Alone (MK-0431-403)
Not yet reported Merck Sharp & Dohme LLC 653 participants Est. completion 2012-02-29Type 2 diabetesView official trial listing → -
Completed NCT NCT01297946
Closed-loop Control of Glucose Levels in the Context of Exercise in Adults With Type-1 Diabetes
Not yet reported, Not yet reported Institut de Recherches Cliniques de Montreal 15 participants 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Terminated NCT NCT01298830
GLP-1 CellBeads® for the Treatment of Stroke Patients With Space-occupying Intracerebral Hemorrhage
Not yet reported, Not yet reported CellMed AG, a subsidiary of BTG plc. 11 participants Est. completion 2011-06 6 sitesOther conditions: Intracerebral Hemorrhage (ICH)View official trial listing → -
Completed NCT NCT01299012
Liraglutide as Additional Treatment in Patients With Type 1 Diabetes Mellitus
University at Buffalo 30 participants Est. completion 2013-06Other conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01300260
Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose
Not yet reported Eli Lilly and Company 32 participants Est. completion 2011-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01304823
Role of the Gut Sweet Taste Receptor in the Secretion of Glucagon-like Peptide-1 and Peptide YY
Not yet reported University Hospital, Basel, Switzerland 10 participants Est. completion 2011-01 1 siteOther conditions: Taste Disorder, Primary, SweetView official trial listing → -
Completed NCT NCT01319240
Safety and Tolerability of Insulin Degludec/Liraglutide (A3) in Healthy Subjects
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2011-05 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01336023
Dual Action of Liraglutide and Insulin Degludec in Type 2 Diabetes: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1663 participants Est. completion 2012-11-22 302 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01341028
Gut Hormones After Roux-en-Y Gastric Bypass (RYGBP) Plus Gastric Fundus Resection
Not yet reported University of Patras 24 participants Est. completion 2010-06 1 siteOther conditions: Morbid ObesityView official trial listing → -
Status unknown NCT NCT01342042
The Safety,Preliminary Pharmacodynamics and Pharmacokinetics Study of rExenatide-4 in Chinese Type 2 Diabetes Mellitus
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 36 participants Est. completion 2011-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01345734
Non-Interventional Study on Safety of Liraglutide in Subjects With Type 2 Diabetes
Novo Nordisk A/S 1056 participants Est. completion 2013-07-26 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01347801
Mechanisms of Insulin Resistance in Critical Illness: Role of Systemic Inflammation and GLP-1
Not yet reported Copenhagen University Hospital, Rigshospitalet 40 participants Est. completion 2014-09 2 sitesOther conditions: HypoglycaemiaView official trial listing → -
Completed NCT NCT01363609
Effects of Glucagon Like Peptide-1(GLP-1) and Liraglutide on Brain Satiety and Reward Circuits and Feeding Behavior in Diabetes
Not yet reported Amsterdam UMC, location VUmc 50 participants Est. completion 2015-01 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT01373216
Glucagon-like Peptide 1 Agonist Exenatide for Improved Glucose Control and Cardiac Function in Patients With Aortocoronary Bypass
Not yet reported Charles University, Czech Republic 38 participants Est. completion 2014-12 1 siteCardiovascular disease Other conditions: Decreased Left Ventricular FunctionView official trial listing → -
Completed NCT NCT01373450
Evaluation of the Glucoregulatory Effects of Glucagon-like Peptide-1 Receptor (GLP-1 Receptor) Activation in Participants With Type 2 Diabetes Mellitus (MK-0000-222)
Not yet reported Merck Sharp & Dohme LLC 12 participants Est. completion 2011-07Type 2 diabetesView official trial listing → -
Completed NCT NCT01375270
Glucolipotoxicity and Type 2 Diabetes
Not yet reported Copenhagen University Hospital, Rigshospitalet 30 participants Est. completion 2014-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01382667
Plasma Levels of Glucagon-like Peptide-2 and Dyspepsia in Patients With Extraintestinal Cancer During Chemotherapy
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis 70 participants Est. completion 2012-01 1 siteOther conditions: Breast Cancer, Lung Cancer, DyspepsiaView official trial listing → -
Completed NCT NCT01388361
Comparison of the Efficacy and Safety of Two Intensification Strategies in Subjects With Type 2 Diabetes Inadequately Controlled on Basal Insulin and Metformin
Not yet reported Novo Nordisk A/S 413 participants Est. completion 2012-07 124 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT01392898
Liraglutide and Insulin Therapy in Patients With Type 2 Diabetes
Not yet reported Radboud University Medical Center 50 participants Est. completion 2014-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01394341
Liraglutide Treatment to Patients With Severe Renal Insufficiency
Not yet reported Bo Feldt-Rasmussen 40 participants Est. completion 2013-10 3 sitesType 2 diabetes Other conditions: End-stage Renal DiseaseView official trial listing → -
Completed NCT NCT01399645
Study of Liraglutide Versus Insulin on Liver Fat Fraction in Patients With Type 2 Diabetes
Not yet reported Centre hospitalier de l'Université de Montréal (CHUM) 35 participants Est. completion 2014-06 1 siteMASLDMASHType 2 diabetesView official trial listing → -
Status unknown NCT NCT01402037
Beta Cell Function in (Pre)Type 1 Diabetes
Not yet reported Universitair Ziekenhuis Brussel 100 participants Est. completion 2016-07 3 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01403025
Evaluating the Safety and Effectiveness of Liraglutide in Subjects With Type 2 Diabetes
Novo Nordisk A/S 4121 participants Est. completion 2015-12-28 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01413126
Peanuts Second Meal Glycemic Response
Not yet reported Federal University of Vicosa 15 participants Est. completion 2011-02 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01413542
Pharmacogenetics of Ace Inhibitor-Associated Angioedema
Not yet reported Vanderbilt University 44 participants Est. completion 2014-07 1 siteOther conditions: Hypertension, Diabetes Type 2View official trial listing → -
Completed NCT NCT01425580
Liraglutide and Heart Failure in Type 2 Diabetes
Not yet reported Thomas Nystrom 62 participants Est. completion 2016-08 2 sitesHeart failureType 2 diabetesView official trial listing → -
Completed NCT NCT01434901
The Effects of Bethanechol on Glucose Homeostasis
Not yet reported Washington University School of Medicine 50 participants Est. completion 2014-07-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01436734
Role of Aprotinin in Glucagon Degradation, Measurement by Radioimmunoactive Method (RIA) I125
Not yet reported University Hospital, Gentofte, Copenhagen 5 participants Est. completion 2013-05 1 siteOther conditions: HyperglucagonemiaView official trial listing → -
Completed NCT NCT01449019
The Role of Endogenous Glucagon-like Peptide 1 (GLP-1) in Type 2 Diabetes Mellitus (T2DM)
Not yet reported Ludwig-Maximilians - University of Munich 24 participants Est. completion 2010-07 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01449747
Pharmacokinetics Study of Dipeptidyl Peptidase 4 Inhibitor to Control Type 2 Diabetes Mellitus
Not yet reported The Catholic University of Korea 24 participants Est. completion 2015-07 2 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01451905
GLP-1 Receptors in Normal Skin and Skin From Patients With Psoriasis
Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2012-12 1 siteOther conditions: Reduction of Psoriasis Following Liraglutide Therapy in Terms of PASI and DLQIView official trial listing → -
Completed NCT NCT01452113
Effect of Autonomic Neuropathy on the Efficacy of a DPP-IV Inhibitor (Galvus) Therapy
Not yet reported University Hospital, Toulouse 21 participants Est. completion 2013-03 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01453842
Diet Oil Induced Stimulation of GLP-1
Not yet reported University of Copenhagen 12 participants Est. completion 2012-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01455441
The Effects of Physical Training and GLP-1 Receptor Agonist Liraglutide Treatment in Patients With Type 2 Diabetes
Not yet reported Tina Vilsboll 40 participants Est. completion 2014-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01456572
Gastric and Intestinal Satiation in Obese and Normal Weight Healthy People
Not yet reported University Hospital, Basel, Switzerland 65 participants Est. completion 2011-07 1 siteOther conditions: Endocrine System DiseasesView official trial listing → -
Completed NCT NCT01460069
The Effect of Glucagon Like Peptide (GLP)-1 in Psoriasis
Not yet reported Annesofie Faurschou 20 participants Est. completion 2013-05 1 siteOther conditions: PsoriasisView official trial listing → -
Completed NCT NCT01461577
Effectiveness and Safety of Treatment of Insulin Glargine in Type 2 Diabetes Mellitus Following Glucagon-like Peptide-1 (GLP-1) Failure
Not yet reported Sanofi 89 participants Est. completion 2012-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01467063
Glutamine and Insulin Sensitivity in Type I Diabetes
Not yet reported Nemours Children's Clinic 13 participants Est. completion 2013-07 1 siteOther conditions: Type I Diabetes MellitusView official trial listing → -
Completed NCT NCT01468181
A Study of LY2189265 in Japanese Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 394 participants Est. completion 2013-12 14 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01469351
Identifying Potential Effects of Liraglutide on Degenerative Changes
Not yet reported University of Aarhus 34 participants Est. completion 2013-04 1 siteOther conditions: Alzheimers DiseaseView official trial listing → -
Suspended NCT NCT01471509
Protein, Amino Acids & Insulin & Glucagon Secretion in Humans
Not yet reported Minneapolis Veterans Affairs Medical Center 300 participants Est. completion 2017-11-06 1 siteType 2 diabetesMetabolic syndromeView official trial listing → -
Completed NCT NCT01472640
The Effect of Liraglutide on Left Ventricular Function in Chronic Heart Failure Patients With and Without Type 2 Diabetes Mellitus
Not yet reported Flyvbjerg, Allan, DMSc 240 participants Est. completion 2015-10 4 sitesHeart failure Other conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT01483651
Physiologic Response to Glucagon at Varying Insulin Levels
Not yet reported Legacy Health System 11 participants Est. completion 2013-03 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01484262
Liraglutide or Insulin in Real Life Usage in Patients With Diabetes Mellitus Type 2
Novo Nordisk A/S 1344 participants Est. completion 2014-10-31 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01499108
Time Course of the Blood Pressure Lowering Effect of Liraglutide Therapy in Type 2 Diabetes
Not yet reported Peter Rossing 32 participants Est. completion 2014-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01503112
Predicting Response to Incretin Based Agents in Type 2 Diabetes
Royal Devon and Exeter NHS Foundation Trust 957 participants Est. completion 2014-04 18 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01505673
Adding Liraglutide to High Dose Insulin: Breaking the Cycle
Not yet reported Ildiko Lingvay 71 participants Est. completion 2016-06 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT01507272
Safety and Tolerability of Liraglutide in Healthy Male Volunteers
Not yet reported Novo Nordisk A/S 34 participants Est. completion 1999-12 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01507285
Safety and Tolerability of Liraglutide in Healthy Volunteers and Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 24 participants Est. completion 1999-11 1 siteType 2 diabetes Other conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01507311
Effect of Liraglutide on Pulsatile Insulin Secretion in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 11 participants Est. completion 1999-12 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01507337
Comparison of the Effect of Liraglutide in Young Versus Elderly Healthy Volunteers
Not yet reported Novo Nordisk A/S 32 participants Est. completion 2004-06 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01507389
Safety of Liraglutide in Subjects With Liver Impairment and in Subjects With Normal Liver Function
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2006-06 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01507597
The Effect of GLP-1 on the Inhibition of Glucagon Secretion
Not yet reported University Hospital, Gentofte, Copenhagen 30 participants Est. completion 2013-08 1 siteType 2 diabetes Other conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01508806
Safety and Tolerability of Liraglutide in Subjects With Impaired Kidney Function and in Subjects With Normal Kidney Function
Not yet reported Novo Nordisk A/S 30 participants Est. completion 2006-03 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01508858
Influence on the Effect of an Oral Contraceptive Drug After Administration of Liraglutide in Postmenopausal Women
Not yet reported Novo Nordisk A/S 21 participants Est. completion 2007-04 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01508897
Comparison of Two Liraglutide Formulations in Healthy Volunteers
Not yet reported Novo Nordisk A/S 22 participants Est. completion 2004-06-30 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01508923
Effect of Liraglutide on Glucose Profiles and Gastric Emptying in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 17 participants Est. completion 2002-02 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01508949
Effect of Liraglutide on Weight and Appetite in Obese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 35 participants Est. completion 2002-03 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01509742
Effect of Liraglutide on Glucagon Secretion in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 19 participants Est. completion 2001-11 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01509755
Comparison of Liraglutide and Glimepiride on Blood Sugar Control in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 196 participants Est. completion 2001-10 29 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01511159
Comparison of Liraglutide Inhaled Into the Lungs Compared to Liraglutide Injected Under the Skin in Healthy Male Volunteers
Not yet reported Novo Nordisk A/S 32 participants Est. completion 2001-12 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01511172
Effect of Liraglutide as add-on to Metformin Compared to Either Liraglutide or Metformin Alone, or to a Combination of Metformin and a SU (Sulphonylurea) Agent in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 145 participants Est. completion 2002-12 41 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01511185
Effect of Liraglutide on the Beta-cell Responsiveness in Subjects With Type 2 Diabetes Compared to a Healthy Control Group
Not yet reported Novo Nordisk A/S 20 participants Est. completion 2001-10 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01511198
Efficacy and Safety of Metformin and Liraglutide in Obese Subjects With Type 2 Diabetes Previously Treated With an Oral Hypoglycemic Agent
Not yet reported Novo Nordisk A/S 223 participants Est. completion 2001-10 39 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Enrolling by invitation NCT NCT01511393
An Active Surveillance Program for Cases of Medullary Thyroid Carcinoma (MTC)
Novo Nordisk A/S 6750 participants Est. completion 2039-12 1 siteType 2 diabetes Other conditions: Diabetes, Medullary Thyroid Carcinoma, Weight ManagementView official trial listing → -
Completed NCT NCT01511692
Effect of Liraglutide Compared to Glimepiride on Appetite in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 43 participants Est. completion 2007-09 2 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01512108
Safety and Efficacy of Liraglutide in Combination With an OAD in Subjects With Type 2 Diabetes Insufficiently Controlled on OAD Alone
Not yet reported Novo Nordisk A/S 363 participants Est. completion 2013-04-26 36 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01513525
Comparison of Liraglutide Injected at Three Different Injection Sites in Healthy Volunteers
Not yet reported Novo Nordisk A/S 21 participants Est. completion 2007-05 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Terminated NCT NCT01514149
Dose-Ranging Study to Evaluate Efficacy and Safety of Weekly CJC-1134-PC in Patients With T2DM on Metformin Monotherapy
Not yet reported ConjuChem 73 participants Est. completion 2013-03 22 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01514487
Comparison of Three Liraglutide Formulations in Healthy Volunteers
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2005-03-30 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01515553
Bioequivalence of Two Liraglutide Formulations in Healthy Volunteers
Not yet reported Novo Nordisk A/S 22 participants Est. completion 2007-04 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01515579
Comparison of Two Liraglutide Formulations in Healthy Subjects
Not yet reported Novo Nordisk A/S 22 participants Est. completion 2006-06 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01515592
Safety and Tolerability of Liraglutide in Healthy Japanese Male Volunteers
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2006-04 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01516255
Effect of Liraglutide on Heart Frequency in Healthy Volunteers
Not yet reported Novo Nordisk A/S 64 participants Est. completion 2006-11 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT01516476
Study of RO6807952 in Patients With Diabetes Mellitus Type 2
Not yet reported Hoffmann-La Roche 2 participants Est. completion 2012-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01517555
Effect of Liraglutide on Absorption of Paracetamol in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 18 participants Est. completion 2007-05 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01517568
Metabolism and Excretion of Liraglutide in Healthy Male Volunteers
Not yet reported Novo Nordisk A/S 7 participants Est. completion 2006-12 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01518101
Vildagliptin Versus Liraglutide - Patient Preference After Receiving Both Medications
Not yet reported Novartis Pharmaceuticals 62 participants Est. completion 2012-10 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01518166
Effect of Liraglutide on Gastrointestinal Absorption of Several Drugs and Potential Influence of Liraglutide on Intragastric pH
Not yet reported Novo Nordisk A/S 70 participants Est. completion 2007-04 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01519102
Comparison of Closed-loop Operation After Morning Meal With and Without Carbohydrate Counting
Not yet reported Institut de Recherches Cliniques de Montreal 12 participants Est. completion 2012-11 1 siteOther conditions: Type-1 DiabetesView official trial listing → -
Completed NCT NCT01524705
FLuctuATion Reduction With inSULin and Glp-1 Added togetheR (FLAT-SUGAR)
Not yet reported University of Washington 102 participants Est. completion 2014-07 12 sitesType 2 diabetesView official trial listing → -
Suspended NCT NCT01527747
Effects of DPP-4 Inhibition on Triglycerides
Not yet reported Oregon Health and Science University 15 participants Est. completion 2024-12 1 siteType 2 diabetes Other conditions: HypertriglyceridemiaView official trial listing → -
Completed NCT NCT01536665
The Effect of Liraglutide Adjunct to Insulin on Glucagon Response to Hypoglycaemia in Subjects With Type 1 Diabetes
Not yet reported Novo Nordisk A/S 45 participants Est. completion 2012-08 1 siteOther conditions: Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01541215
Efficacy and Safety of Liraglutide in Combination With Metformin Compared to Metformin Alone, in Children and Adolescents With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 135 participants Est. completion 2020-05-20 185 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT01542242
Liraglutide Use in Prader-Willi Syndrome
Not yet reported Vancouver General Hospital 1 participants Est. completion 2013-03 1 siteType 2 diabetes Other conditions: Prader Willi SyndromeView official trial listing → -
Completed NCT NCT01550653
Liraglutide Effects on Memory in Healthy Subjects
Not yet reported University of Luebeck 40 participants Est. completion 2013-12 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01552603
Artificial Pancreas Control System in an Inpatient Setting
Not yet reported Legacy Health System 14 participants Est. completion 2013-09 2 sites Stand-aloneOther conditions: Type I Diabetes MellitusView official trial listing → -
Completed NCT NCT01556594
Safety and Efficacy of a Novel Glucagon Formulation in Type 1 Diabetic Patients Following Insulin-induced Hypoglycemia
Not yet reported Eli Lilly and Company 18 participants Est. completion 2012-07 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT01557166
Effect of Liraglutide in Obese Subjects With Moderate or Severe Obstructive Sleep Apnoea: SCALE™ - Sleep Apnoea
Not yet reported Novo Nordisk A/S 359 participants Est. completion 2013-06-17 42 sitesOther conditions: Metabolism and Nutrition Disorder, Obesity, Obstructive Sleep ApnoeaView official trial listing → -
Completed NCT NCT01558271
A Study of LY2189265 in Japanese Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 492 participants Est. completion 2014-05 14 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01562678
Liraglutide in Obesity and Diabetes: Identification of CNS Targets Using fMRI
Not yet reported Beth Israel Deaconess Medical Center 28 participants Est. completion 2014-05 1 siteOther conditions: Diabetes, Effects of Liraglutide Administration on Brain Activity, Weight Loss, HungerView official trial listing → -
Completed NCT NCT01572740
Efficacy and Safety of Liraglutide in Combination With Insulin Therapy Compared to Insulin Alone in Japanese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 257 participants Est. completion 2013-03-27 23 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT01573286
Safety and Dosing Study of Glucagon-like Peptide 2 (GLP-2) in Infants and Children With Intestinal Failure
Not yet reported, Not yet reported Alberta Children's Hospital 13 participants Est. completion 2015-08 4 sitesOther conditions: Intestinal Failure, Short Bowel SyndromeView official trial listing → -
Completed NCT NCT01575301
DIabetes REsearCh on Patient sTratification (DIRECT): GLP-1R Agonists
Not yet reported University of Dundee 411 participants Est. completion 2015-12-11 4 sitesOther conditions: DiabetesView official trial listing → -
Completed NCT NCT01579981
The Importance of GLP-1 in Post RYGB Improvement in Glycaemic Control Type 2 Diabetic Subjects
Not yet reported Hvidovre University Hospital 9 participants Est. completion 2012-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01584232
A Study of Dulaglutide in Japanese Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 361 participants Est. completion 2013-07 15 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01592279
GLP-1 Analogue Treatment in Uncontrolled Type 1 Diabetic Patients
Not yet reported Hadassah Medical Organization 124 participantsOther conditions: Uncontrolled Type 1 Diabetic PatientsView official trial listing → -
Withdrawn NCT NCT01593137
A Long-term Trial to Compare the Effects of Liraglutide and Sulphonylurea (Glimepiride) Both in Combination With Metformin on Clinical, Endothelial and Image Markers of Cardiovascular Risk in Patients With Type 2 Diabetes
Not yet reported Fundación Fernández-Cruz Est. completion 2014-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01593605
Resveratrol-Leucine Metabolite Synergy in Pre-diabetes
Not yet reported Vanderbilt University 36 participants Est. completion 2013-06 1 sitePrediabetesView official trial listing → -
Completed NCT NCT01595789
The Effect of Liraglutide on the Treatment of Coronary Artery Disease and Type 2 Diabetes
Not yet reported Haugaard, Steen Bendix, M.D., DMSc 41 participants Est. completion 2015-07 1 siteCardiovascular diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT01596504
Pharmacodynamic Effects of Lixisenatide Compared to Liraglutide in Patients With Type 2 Diabetes Not Adequately Controlled With Insulin Glargine With or Without Metformin
Not yet reported Sanofi 142 participants Est. completion 2013-07 8 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT01597531
Combinatorial Therapy for Peristent Type 2 Diabetes After Gastric Banding
Not yet reported East Carolina University 1 participants Est. completion 2014-06 1 siteType 2 diabetes Other conditions: Gastric BandingView official trial listing → -
Completed NCT NCT01599338
Impact of Liraglutide on Sensory Perception, Sensory Specific Satiety, Liking and Wanting in Type 2 Diabetic Patients
Not yet reported Centre Hospitalier Universitaire Dijon 30 participants Est. completion 2011-09 1 siteType 2 diabetes Other conditions: OverweightView official trial listing → -
Completed NCT NCT01606423
The Effect of LY2409021 on Blood Sugar Levels When Glucagon Levels Are Increased in Healthy Male Participants
Not yet reported Eli Lilly and Company 21 participants Est. completion 2008-03 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT01607450
Modulation of Human Myocardial Metabolism by GLP-1 Dose Response
Not yet reported, Not yet reported Indiana University 33 participants Est. completion 2012-12 1 siteType 2 diabetes Other conditions: HealthyView official trial listing → -
Completed NCT NCT01607931
Exercise, Glucose Kinetics, and the Incretin Effect
Not yet reported Copenhagen University Hospital, Rigshospitalet 12 participants Est. completion 2016-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01610154
Contribution of Pancreatic αcells Function to Blood Glucose Regulation in Chinese Type 2 Diabetics- the Effect of Sitagliptin on Glucagon Secretion, Insulin Secretion and Insulin Resistance in Chinese Type 2 Diabetics
Not yet reported Guangwei Li 85 participants Est. completion 2015-06 1 siteOther conditions: Insulin Secretion, Insulin ResistanceView official trial listing → -
Completed NCT NCT01610934
The Effects of GLP-1 in Maturity-Onset Diabetes of The Young (MODY)
Not yet reported, Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2013-08 1 siteOther conditions: Maturity-onset Diabetes of the YoungView official trial listing → -
Completed NCT NCT01612468
Liraglutide in Type 1 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 100 participants Est. completion 2015-02 1 siteOther conditions: Diabetes Mellitus, Type 1, OverweightView official trial listing → -
Completed NCT NCT01615978
Safety and Tolerability of Liraglutide in Japanese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 15 participants Est. completion 2004-03 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01617434
The Effect of Liraglutide Versus Placebo When Added to Basal Insulin Analogues With or Without Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 451 participants Est. completion 2013-10 86 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01620463
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Liraglutide in Healthy Japanese Volunteers
Not yet reported Novo Nordisk A/S 32 participants Est. completion 2003-03 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01620476
Safety and Tolerability of Liraglutide in Healthy Japanese Volunteers
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2004-03 1 siteOther conditions: Diabetes, HealthyView official trial listing → -
Completed NCT NCT01620489
Efficacy and Safety of Liraglutide Versus Placebo as add-on to Existing Diabetes Medication in Subjects With Type 2 Diabetes and Moderate Renal Impairment
Not yet reported Novo Nordisk A/S 279 participants Est. completion 2013-08-20 97 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01624259
A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes
Not yet reported Eli Lilly and Company 599 participants Est. completion 2013-11 57 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT01628445
Study of Liraglutide in Individuals With Type 2 Diabetes Using Insulin
Not yet reported University of Manitoba 52 participants Est. completion 2015-11 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT01638260
GLP-1 and Non-exercise Activity Thermogenesis in RHZ
Not yet reported Maastricht University Medical Center 22 participants Est. completion 2013-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01640834
Study of LY2409021 in Participants With Type 1 Diabetes
Not yet reported Eli Lilly and Company 20 participants Est. completion 2012-09 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT01642108
Treatment With Sitagliptin in Non-obese Japanese Patients With Type 2 Diabetes Mellitus
Not yet reported Niigata Medical Center 40 participants Est. completion 2013-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01654120
Study of Effectiveness of Liraglutide Added to High Dose Insulin in Type II Diabetics
Not yet reported Mountain Diabetes and Endocrine Center 37 participants Est. completion 2013-11 1 siteOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT01656057
The Impact of Gall Bladder Emptying and Bile Acids on the Human GLP-1-secretion
Not yet reported Filip Krag Knop 10 participants Est. completion 2014-04 1 siteOther conditions: To Assess the Impact of Bile Acids on Human Glukagon-like-peptide-1 SecretionView official trial listing → -
Completed NCT NCT01658501
Phase 2b Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel-Group Study to Assess the PD Response and Safety of Three Dose Levels of (PB1023) Injection Following 20 Weeks of Weekly SC Dosing in Adults With T2DM
Not yet reported PhaseBio Pharmaceuticals Inc. 593 participants Est. completion 2013-07 93 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01664247
The Effect of Insulin Degludec in Combination With Liraglutide and Metformin in Subjects With Type 2 Diabetes Qualifying for Treatment Intensification
Not yet reported Novo Nordisk A/S 346 participants Est. completion 2013-12-31 132 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01664676
Effects of Liraglutide on Kidney Function in Type 2 Diabetic Patients
Not yet reported University of Aarhus 11 participants Est. completion 2014-02 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT01671579
Comparison of Bowel Ultrasound & MR Enterography in the Follow-up of Previously Diagnosed Pediatric Small Bowel Crohn Disease
Not yet reported Children's Hospital Medical Center, Cincinnati 33 participants Est. completion 2017-08 1 siteOther conditions: Crohn DiseaseView official trial listing → -
Withdrawn NCT NCT01674283
Effect of Glucagon on Uterine Contractility at the Time of Embryo Transfer in in Vitro Fertilization
Not yet reported Clinique Ovo Est. completion 2013-10 1 siteOther conditions: Women With Fertility DisorderView official trial listing → -
Completed NCT NCT01674972
Glucose-induced Glucagon-like Peptide 1 (GLP-1) Secretion in NAFLD Patients Compared to Healthy Controls
University Hospital, Basel, Switzerland 102 participants Est. completion 2012-06 1 siteOther conditions: Non Alcoholic Fatty Liver Disease, Non Alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT01676116
The Efficacy of Insulin Degludec/Liraglutide in Controlling Glycaemia in Adults With Type 2 Diabetes Inadequately Controlled on GLP-1 Receptor Agonist and OAD Therapy
Not yet reported Novo Nordisk A/S 438 participants Est. completion 2014-03-11 109 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01677104
The Microvascular Function of GLP-1 and Its Analogues
Not yet reported Katarina Kos 63 participants Est. completion 2014-07 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT01680653
Testing State of the Art Remote Glucose Monitoring at Diabetes Camp
Not yet reported Stanford University 57 participants Est. completion 2012-09 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT01684956
Pharmacokinetic Comparison of Intradermal Versus Sub-cutaneous Insulin and Glucagon Delivery in Type 1 Diabetes
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2017-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01687582
Effect of GLP-1 Analogs on Psoriasis in Type 2 Diabetic Patients
Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 10 participants Est. completion 2013-03 1 siteType 2 diabetes Other conditions: PsoriasisView official trial listing → -
Completed NCT NCT01689051
Vasodilatory and Metabolic Effects of Glucagon-like Peptide-1 in Periphery Circulation in Patients With and Without Type 2 Diabetes Mellitus
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2013-04 1 siteType 2 diabetes Other conditions: Blod Pressure, Glucagon-like Peptide-1, Human Physiology, Blood FlowView official trial listing → -
Completed NCT NCT01695109
The Influence of Liraglutide on the Reward Properties of Food: an fMRI Study on Healthy Volunteers
Not yet reported Medical University of Vienna 16 participants Est. completion 2012-03 1 siteOther conditions: Healthy Human Male SubjectsView official trial listing → -
Completed NCT NCT01698502
Physical Training and the Incretin Effect
University of Copenhagen 21 participants Est. completion 2013-06 1 siteOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT01722227
Anti-diabetic Effects of Liraglutide in Adolescents and Young Subjects With Type 1 Diabetes
Not yet reported University at Buffalo Est. completion 2018-05 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01722240
Liraglutide in Type 1 Diabetes
Not yet reported University at Buffalo 69 participants Est. completion 2019-07-29 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01722266
Liraglutide in the Treatment of Type 1 Diabetes Mellitus
Not yet reported University at Buffalo 72 participants Est. completion 2014-12-01 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01725126
To Investigate the Safety, Tolerability and Pharmacodynamics of GSK2890457 in Healthy Volunteers and Subjects With Type 2 Diabetes
Not yet reported GlaxoSmithKline 53 participants Est. completion 2013-09-12 3 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT01733758
A Monotherapy Study to Evaluate the Efficacy and Safety of 2 Dose Levels of Albiglutide in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM)
Not yet reported GlaxoSmithKline 494 participants Est. completion 2015-02 74 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01739049
Influence of Appetite Related Hormones in Binge Eating Behaviour Among the Overweight and Obese
Not yet reported Universiti Kebangsaan Malaysia Medical Centre 42 participants Est. completion 2015-01 1 siteOther conditions: Binge Eating BehaviourView official trial listing → -
Completed NCT NCT01739283
GIP and GLP-1 in Type 1 Diabetes
Not yet reported Mikkel Christensen 10 participants Est. completion 2013-11 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT01740921
GLP-1 and Microvascular Function in Type 2 Diabetes
Not yet reported Royal Devon and Exeter NHS Foundation Trust 39 participants Est. completion 2016-02 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT01741103
Sitagliptin in Type I Diabetic Patients
Not yet reported University at Buffalo Est. completion 2013-09 1 siteOther conditions: Diabetes Type IView official trial listing → -
Completed NCT NCT01744236
SAFEGUARD: Pleiotropic Effects of Incretin Based Therapies
Not yet reported Amsterdam UMC, location VUmc 70 participants Est. completion 2015-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01747967
Immune Biomarkers of Residual Beta-cell Mass in Type 1 Diabetes
Not yet reported Assistance Publique - Hôpitaux de Paris 156 participants Est. completion 2017-05-30 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01749163
Hyperglycemia and the Extra-pancreatic Effect of Incretins
Not yet reported Copenhagen University Hospital, Rigshospitalet 20 participants Est. completion 2014-03 1 siteOther conditions: Extra-pancreatic Incretin Effect, Glucose EffectivenessView official trial listing → -
Completed NCT NCT01753362
Liraglutide In Overweight Patients With Type 1 Diabetes
Not yet reported University at Buffalo 84 participants Est. completion 2018-02 2 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01754337
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 24 Hours in Adults and Adolescents With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 30 participants Est. completion 2014-06 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01755416
Liraglutide Versus Insulin Mono-therapy in the Closed Loop Setting
Not yet reported Albert Einstein College of Medicine 18 participants Est. completion 2015-01 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01755572
Blood Pressure Outcomes With Liraglutide Therapy
Not yet reported Mount Sinai Hospital, Canada 22 participants Est. completion 2014-03 1 siteType 2 diabetes Other conditions: Systolic HypertensionView official trial listing → -
Completed NCT NCT01759823
Bone Marrow Derived Stem Cell Transplantation in T2DM
Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 30 participants Est. completion 2015-10 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT01760772
Effect of GLP-1 on Postprandial Lipid Metabolism
Not yet reported David Dalessio 42 participants Est. completion 2015-02 1 siteOther conditions: Heart DiseaseView official trial listing → -
Completed NCT NCT01761318
Effect of Liraglutide on Cardiovascular Endpoints in Diabetes Mellitus Type 2 Patients
Not yet reported Leiden University Medical Center 50 participants Est. completion 2016-03 1 siteType 2 diabetesMetabolic syndromeCardiovascular disease Other conditions: Diastolic Dysfunction, Fatty LiverView official trial listing → -
Completed NCT NCT01762059
Outpatient Automated Blood Glucose Control With a Bi-hormonal Bionic Endocrine Pancreas
Not yet reported Massachusetts General Hospital 32 participants Est. completion 2014-06 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01767389
Glucagon-like Peptide (GLP) Utilization and Safety
GlaxoSmithKline 1 participants Est. completion 2013-12Type 2 diabetesView official trial listing → -
Completed NCT NCT01777282
A Study to Determine the Long Term Safety and Efficacy of Albiglutide in Combination With Oral Monotherapy Antihyperglycemic Medications in Japanese Patients With Type 2 Diabetes Mellitus
Not yet reported GlaxoSmithKline 374 participants Est. completion 2015-01-27 49 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01779362
RISE Adult Medication Study
Not yet reported RISE Study Group 267 participants Est. completion 2019-08 4 sitesPrediabetesType 2 diabetesView official trial listing → -
Completed NCT NCT01779622
Rapid Versus Slow Ingestion of Mixed Meal: Influence on Islet and Incretin Hormone Secretion in Healthy Volunteers
Not yet reported Lund University 24 participants Est. completion 2014-06 1 siteOther conditions: Healthy Volunteers Recruited From the General PopulationView official trial listing → -
Completed NCT NCT01782261
Incretin Effect on the Immunological Phenotype
Not yet reported Medical University of Graz 15 participants Est. completion 2015-02 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01784965
Liraglutide and a Calorie Restricted Diet Augments Weight Loss and Decreases Risk of Type 2 Diabetes and CVD.
Not yet reported Stanford University 69 participants Est. completion 2012-12Prediabetes Other conditions: Older AdultsView official trial listing → -
Completed NCT NCT01785043
Differences in Endothelial Function Amongst Sitagliptin and Liraglutide Users
Not yet reported Anna Cruceta 13 participants Est. completion 2014-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01787916
52 Week Trial of Liraglutide in Type 1 Diabetes
Not yet reported CHU de Quebec-Universite Laval 15 participants Est. completion 2015-04 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01789086
A Randomised, Double-blind, Placebo-controlled Trial to Assess Safety, Tolerability and Pharmacokinetics of Liraglutide in Obese Adolescent Subjects Aged 12 to 17 Years
Not yet reported Novo Nordisk A/S 21 participants Est. completion 2014-05 1 siteOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Status unknown NCT NCT01790308
Effect of Liraglutide Combined With Short-term CSII on Long-term Glycemic Remission and β Cell Function
Not yet reported Sun Yat-sen University 100 participants Est. completion 2015-12Type 2 diabetesView official trial listing → -
Completed NCT NCT01794143
A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 Diabetes
Not yet reported GRADE Study Group 7850 participants Est. completion 2021-04-30 36 sitesType 2 diabetes Other conditions: Comparative Effectiveness of Glycemia-lowering MedicationsView official trial listing → -
Completed NCT NCT01795144
Incretin Regulation of Insulin Secretion in Monogenic Diabetes
Not yet reported University of Chicago 10 participants Est. completion 2017-03 1 siteOther conditions: Monogenic DiabetesView official trial listing → -
Status unknown NCT NCT01795235
Study of Glucagon, Ghrelin and Growth Hormone as Counterregulatory Hormones
Not yet reported University of Virginia 6 participants Est. completion 2014-07 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01795248
The Impact of Liraglutide on Glucose Tolerance and the Risk of Type 2 Diabetes in Women With Previous Pregnancy-induced Diabetes
Not yet reported Tina Vilsboll 105 participants Est. completion 2020-09 1 siteOther conditions: Gestational Diabetes MellitusView official trial listing → -
Status unknown NCT NCT01800734
Mixed Meal Test in Type 1 Diabetes: Optimization of Artificial Pancreas-Pilot Study
Not yet reported Azienda Ospedaliera Universitaria Integrata Verona 20 participants Est. completion 2015-02 1 siteOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT01800968
Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)
Not yet reported Duke University 300 participants Est. completion 2015-10 25 sitesHeart failureView official trial listing → -
Status unknown NCT NCT01804413
Pegvisomant With Glucagon Test to Assess for Adult Growth Hormone Deficiency
Not yet reported Oregon Health and Science University 10 participants Est. completion 2013-12 1 siteOther conditions: Adults Growth Hormone Deficiency.View official trial listing → -
Withdrawn NCT NCT01818648
Exenatide on GI Motor Function and Permeability in Short Bowel Syndrome
Not yet reported Mayo Clinic Est. completion 2014-01Other conditions: Short Bowel SyndromeView official trial listing → -
Completed NCT NCT01821846
Investigating the Safety Profile of Liraglutide Under Normal Conditions of Use in Korean Subjects With Type 2 Diabetes Mellitus
Novo Nordisk A/S 64 participants Est. completion 2017-03-08 7 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Withdrawn NCT NCT01828125
Efficacy of Small Subcutaneous Glucagon Dose to Treat Hypoglycemia in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal Est. completion 2013-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01832532
A Pilot Study of the Effects on Sleep Disordered Breathing (SDB) When Using the Drug Liraglutide for 4 Weeks
Not yet reported, Not yet reported Children's Hospital Medical Center, Cincinnati 34 participants Est. completion 2015-12 1 siteOther conditions: Sleep Apnea, Sleep Disordered BreathingView official trial listing → -
Completed NCT NCT01833988
The Summer Camp Study: Blood Glucose Control With a Bi-Hormonal Bionic Endocrine Pancreas
Not yet reported Massachusetts General Hospital 32 participants Est. completion 2014-12 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01835964
Biobehavioral Mechanisms of Glucose Variability
Not yet reported University of Virginia 30 participants Est. completion 2014-02 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01836523
The Efficacy and Safety of Liraglutide as Adjunct Therapy to Insulin in the Treatment of Type 1 Diabetes
Not yet reported Novo Nordisk A/S 1398 participants Est. completion 2015-06 182 sitesOther conditions: Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT01843075
Evaluating Liraglutide in Alzheimer's Disease
Not yet reported Imperial College London 204 participants Est. completion 2019-12 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01843127
A Study to Evaluate the Effect of Ranolazine on Postprandial Glucagon in Subjects With Type 2 Diabetes.
Not yet reported Gilead Sciences 24 participants Est. completion 2013-09 3 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01845259
Does a GLP-1 Receptor Agonist Change Glucose Tolerance in Antipsychotic-treated Patients?
Not yet reported Psychiatric Centre Rigshospitalet 103 participants Est. completion 2017-03 1 sitePrediabetesView official trial listing → -
Completed NCT NCT01847313
The Effect of Glucagon-like-peptide 1 (GLP-1) Receptor Agonism on Diabetic Kidney Disease
Not yet reported Karl Neff 20 participants Est. completion 2015-11 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT01856790
Effect of Liraglutide on Automated Closed-loop Glucose Control in Type 1 Diabetes
Not yet reported Jennifer Sherr 15 participants Est. completion 2015-11 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Active, not recruiting NCT NCT01858896
GLP-1 and Hypoglycemia
Not yet reported University of Maryland, Baltimore 28 participants Est. completion 2026-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01865760
Etiology, Assessment and Treatment of Post-gastric Bypass Severe Hypoglycemia
Not yet reported University of Aarhus 33 participants Est. completion 2016-03 1 siteOther conditions: Obesity, Hypoglycemia, SurgeryView official trial listing → -
Completed NCT NCT01870297
A Study of LY3025876 in Participants With Diabetes
Not yet reported Eli Lilly and Company 72 participants Est. completion 2014-12 4 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01871870
Artificial Pancreas Control System in an Outpatient Setting
Not yet reported Legacy Health System 20 participants Est. completion 2013-10 1 site Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01875575
Oral Glucose Stimulation in Normal-weight and Obese Volunteers
Not yet reported University Hospital, Basel, Switzerland 24 participants Est. completion 2013-04 1 siteOther conditions: Endocrine System DiseasesView official trial listing → -
Completed NCT NCT01879917
Liraglutide in Newly Onset Type 1 Diabetes.
Not yet reported, Not yet reported Hvidovre University Hospital 65 participants Est. completion 2018-08 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01880827
Splanchnic Blood Redistribution After Incretin Hormone Infusion and Obesity Surgery
Not yet reported Turku University Hospital 36 participants Est. completion 2016-01 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT01890993
Retrospective Collection of Effectiveness and Safety Data From Patients Treated With Liraglutide or DPP-4 Inhibitor in Primary Care in Europe
Novo Nordisk A/S 952 participants Est. completion 2014-06 4 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01899430
Polycystic Ovary Syndrome and Liraglutide
Not yet reported University Medical Centre Ljubljana 32 participants Est. completion 2013-04 1 siteOther conditions: PCOS, ObesityView official trial listing → -
Completed NCT NCT01900340
Intestinal Glucagon-like Peptide-1 (GLP-1) and the Physiological Role in Eating in Humans
Not yet reported University Hospital, Basel, Switzerland 12 participants Est. completion 2012-12 1 siteOther conditions: Appetite and General Nutritional DisordersView official trial listing → -
Completed NCT NCT01905020
Closed-loop Control of Overnight Glucose Levels in Adults and Adolescents With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 28 participants Est. completion 2014-09 3 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01907854
Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and Metformin
Not yet reported Novo Nordisk A/S 407 participants Est. completion 2015-06-15 106 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01911468
Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin
Not yet reported University Medical Centre Ljubljana 36 participants Est. completion 2013-04 1 siteOther conditions: PCOS, ObesityView official trial listing → -
Completed NCT NCT01916265
Trial to Compare the Relative Pharmacodynamic Properties of Different Glucagon Dosages
Not yet reported Profil Institut für Stoffwechselforschung GmbH 6 participants Est. completion 2013-11 1 siteOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT01917656
Efficacy and Safety of Liraglutide Versus Sulphonylurea Both in Combination With Metformin During Ramadan in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 343 participants Est. completion 2014-09-04 41 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01917760
Pharmacokinetics Study of Gamma-aminobutyric Acid
Huashan Hospital 12 participants Est. completion 2014-12 1 siteOther conditions: Diabetes Mellitus, Diabetes Mellitus, Type 1, Glucose Metabolism Disorders, Metabolic Diseases, Endocrine System Diseases, Autoimmune Diseases, Immune System DiseasesView official trial listing → -
Completed NCT NCT01919489
Liraglutide Hospital Discharge Trial
Not yet reported Emory University 273 participants Est. completion 2020-08-30 5 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01919684
Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes Mellitus
Not yet reported Ligand Pharmaceuticals 56 participants Est. completion 2014-03 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01930097
Closed-loop Control of Glucose Levels After Meal Intake in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 12 participants Est. completion 2014-02 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01930110
Closed-loop Control of Glucose Levels (Artificial Pancreas) During Exercise in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 15 participants Est. completion 2015-04 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01931982
Effect of Glucagon-like Peptide 1 (GLP-1) on Microvascular Myocardial Function in Patients With Type 2 Diabetes.
Not yet reported Bispebjerg Hospital 20 participants Est. completion 2014-04 1 siteType 2 diabetes Other conditions: Microvascular DysfunctionView official trial listing → -
Terminated NCT NCT01934816
Incretin and KATP Channels
Not yet reported Katarina Kos 2 participants Est. completion 2015-10 1 siteOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT01935791
Investigating Brown Adipose Tissue Activation in Humans
Not yet reported Imperial College London 11 participants Est. completion 2018-11-05 1 siteOther conditions: Metabolic DiseasesView official trial listing → -
Completed NCT NCT01937598
Antidiabetic Effects of Adding a DPP-4 Inhibitor to Pre-Existing Treatment With an Incretin Mimetic in Patients With T2D
Not yet reported Michael A. Nauck 16 participants Est. completion 2015-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01938469
Effect of Meal Number, Frequency, and Form on Satiety and Metabolism After Weight Loss Surgery
Not yet reported St. Luke's-Roosevelt Hospital Center 33 participants Est. completion 2014-07 1 siteOther conditions: Gastric Bypass Surgery, ObesityView official trial listing → -
Withdrawn NCT NCT01951716
Effects of Xenin-25 on Insulin Secretion and Gastric Emptying in Humans With and Without a Complete Truncal Vagotomy
Not yet reported Washington University School of Medicine Est. completion 2018-07 1 siteOther conditions: Does the Vagus Nerve Mediate the Effects of Xenin-25View official trial listing → -
Completed NCT NCT01951729
The Role of Cholinergic Signaling for Mediating the Effects of GIP and/or Xenin-25 on Insulin Secretion
Not yet reported Washington University School of Medicine 15 participants Est. completion 2015-05 1 sitePrediabetesView official trial listing → -
Status unknown NCT NCT01954147
Umbilical Cord Mesenchymal Stem Cells and Liraglutide in Diabetes Mellitus
Not yet reported, Not yet reported Diabetes Care Center of Nanjing Military Command 100 participants Est. completion 2015-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01956929
Metformin's Effect on Glucagon-induced Glucose Production and Protein Metabolism.
Not yet reported Mayo Clinic 12 participants Est. completion 2016-03 1 siteOther conditions: Insulin Resistance, Prediabetic StateView official trial listing → -
Completed NCT NCT01958775
Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon Like Peptide 2
Not yet reported University Health Network, Toronto 12 participants Est. completion 2014-06 1 siteOther conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT01959334
Evaluate the Immunogenicity of a Novel Glucagon Formulation
Not yet reported Eli Lilly and Company 75 participants Est. completion 2013-12 1 siteOther conditions: Drug-specific Antibodies, Diabetes MellitusView official trial listing → -
Completed NCT NCT01966393
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 60 Hours in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 23 participants Est. completion 2015-04 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT01966978
The Effect of Simple Basal Insulin Titration, Metformin Plus Liraglutide for Type 2 Diabetes With Very Elevated HbA1c - The SIMPLE Study
Not yet reported University of Texas Southwestern Medical Center 157 participants Est. completion 2017-12 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01972152
Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of G-Pen(TM) (Glucagon Injection) to Treat Severe Hypoglycemia
Not yet reported Xeris Pharmaceuticals 30 participants Est. completion 2014-02 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT01972542
The Usefulness of Postprandial Triglyceride for Assessment of Cardiovascular Risk
Not yet reported Seoul National University Bundang Hospital 80 participants Est. completion 2015-08 1 sitePrediabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01972893
A Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ZYD1, Following Subcutaneous Administration in Healthy Volunteers
Not yet reported Zydus Lifesciences Limited 56 participants Est. completion 2012-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01973231
Efficacy and Safety of Liraglutide Versus Lixisenatide as add-on to Metformin in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 404 participants Est. completion 2014-11 61 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01975259
Investigating the Incretin Effect in Cystic Fibrosis
Liverpool Heart and Chest Hospital NHS Foundation Trust 50 participants Est. completion 2015-07 1 siteOther conditions: Cystic FibrosisView official trial listing → -
Completed NCT NCT01982630
Study of the Safety and Efficacy of MK-8521 Compared to Placebo and a Diabetes Drug in Participants With Type 2 Diabetes Mellitus (MK-8521-003)
Not yet reported Merck Sharp & Dohme LLC 87 participants Est. completion 2014-10-03Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT01986231
Safety Study of Repeated Doses of Glucagon on Animal Starch in the Liver
Not yet reported Legacy Health System 12 participants Est. completion 2012-12 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01994746
Efficacy and Safety of Nasal Glucagon for Treatment of Hypoglycemia in Adults
Not yet reported Eli Lilly and Company 77 participants Est. completion 2015-01 8 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01997411
Assessment of Intranasal Glucagon in Children and Adolescents With Type 1 Diabetes
Not yet reported, Not yet reported Eli Lilly and Company 48 participants Est. completion 2015-01 7 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01999504
Gut Hormone Response After Paleolithic-type Meals
Not yet reported Unilever R&D 24 participants Est. completion 2014-10 1 siteOther conditions: Insulin Resistance, SatietyView official trial listing → -
Status unknown NCT NCT02001363
Efficacy Study of Glucagonlike Peptide-1 to Treat Reperfusion Injury
Not yet reported Chen Wei Ren, MD 90 participants Est. completion 2016-03 1 siteCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT02003274
Mixed Meal Test in Type 1 Diabetes on Insulin Pump Therapy: Optimization of Artificial Pancreas
Not yet reported Azienda Ospedaliera Universitaria Integrata Verona 20 participants Est. completion 2017-10-31 2 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02006459
Involvement of Extrapancreatic Factors on Gastrointestinal-mediated Glucose Disposal
University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2015-10 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02008682
The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 368 participants Est. completion 2014-11 25 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02010827
Endogenous Glucoseproduction in Patients With Type 2 Diabetes Mellitus During Oral Glucose and iv. Glucose Infusion
University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2015-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02012166
A Study of MK-0893 on Glucagon-Induced Glycemic Excursion in Healthy Male Participants Following Intravenous Administration of Glucagon, Sandostatine® and Insulin (MK-0893-002)
Not yet reported Merck Sharp & Dohme LLC 18 participants Est. completion 2005-12Type 2 diabetesView official trial listing → -
Completed NCT NCT02014740
Effect of Liraglutide on Epicardial Fat in Subjects With Type 2 Diabetes
Not yet reported University of Miami 100 participants Est. completion 2017-03 1 siteType 2 diabetes Other conditions: Overweight, ObesityView official trial listing → -
Withdrawn NCT NCT02015780
Fasiglifam in Type 2 Diabetic Subjects With Chronic Kidney Disease Stage 4 or 5 on Hemodialysis
Not yet reported Takeda Est. completion 2016-01 30 sitesType 2 diabetesChronic kidney diseaseView official trial listing → -
Status unknown NCT NCT02016846
Liraglutide Efficacy on Glucocorticoid Induced Hyperglycemia in Patients High Risk for Diabetes
Not yet reported Rabin Medical Center 36 participants 1 siteOther conditions: Glucocorticoid Induced HyperglycemiaView official trial listing → -
Completed NCT NCT02018627
Equivalence of A Stable Liquid Glucagon Formulation With Freshly Reconstituted Lyophilized Glucagon
Not yet reported, Not yet reported Steven J. Russell, MD, PhD 20 participants Est. completion 2018-08-02 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02020629
Study on Lixisenatide and Counterregulation to Hypoglycemia
Not yet reported Lund University 18 participants Est. completion 2015-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02036372
Perioperative Insulin, GIK or GLP-1 Treatment in Diabetes Mellitus
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 150 participants Est. completion 2017-01 3 sitesOther conditions: Diabetes Mellitus Type IIView official trial listing → -
Completed NCT NCT02036710
Location of GLP-1 Release
University of Minnesota 12 participants Est. completion 2013-10 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02041234
Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes Versus Best Medical Treatment
Not yet reported Khoo Teck Puat Hospital 40 participants Est. completion 2022-06 1 siteOther conditions: Type II Diabetes in Subjects BMI 27 to 32View official trial listing → -
Completed NCT NCT02043054
Effects of Liraglutide in Young Adults With Type 2 DIAbetes (LYDIA)
Not yet reported University of Leicester 90 participants Est. completion 2017-09-29 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT02055014
Randomisation to Endobarrier Alone Versus With Incretin Analogue in SustainEd Diabesity (REVISE-Diabesity)
Not yet reported Sandwell & West Birmingham Hospitals NHS Trust 72 participants Est. completion 2017-03 4 sitesType 2 diabetes Other conditions: Obesity, DiabesityView official trial listing → -
Completed NCT NCT02057172
Glycaemic Control of Weekly LAPS-Exendin Versus Placebo in Subjects of Type 2 Diabetes
Not yet reported Hanmi Pharmaceutical Company Limited 254 participants Est. completion 2014-12 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02059564
A Phase 1b Study of LAPS-Exendin in Subjects of Type 2 Diabetes Mellitus
Not yet reported Hanmi Pharmaceutical Company Limited 44 participants Est. completion 2014-12 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02060383
Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or Acromegaly
Not yet reported Novartis Pharmaceuticals 249 participants Est. completion 2018-03-26 43 sitesOther conditions: Cushing's Disease, AcromegalyView official trial listing → -
Terminated NCT NCT02072096
A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Eli Lilly and Company 192 participants Est. completion 2015-10 34 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02073929
LIPT - Liraglutide in Polycystic Ovary Syndrome
Not yet reported Jens Faber 72 participants Est. completion 2015-12 3 sitesCardiovascular disease Other conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02075281
Effect of LAPS-Exendin on Body Weight in Obese Population
Not yet reported Hanmi Pharmaceutical Company Limited 297 participants Est. completion 2015-02 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02077946
A Retrospective Database Assessment of Clinical Effectiveness in Type 2 Diabetes Patients Treated With Liraglutide From Primary Care Centers in Sweden
Novo Nordisk A/S 1059 participants Est. completion 2014-09-03 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02078726
Glucagon Use in Colonoscopies
Not yet reported University of California, San Francisco 100 participants Est. completion 2018-05 1 siteOther conditions: Colon CancerView official trial listing → -
Completed NCT NCT02081001
PK/PD Study With G-Pump (Glucagon Infusion) in T1DM Patients
Not yet reported Xeris Pharmaceuticals 19 participants Est. completion 2014-09 1 site Stand-aloneOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02081014
Safety and Efficacy Study of Mini-Dose Glucagon (G-Pen Mini) in Patients With Type 1 Diabetes
Not yet reported Xeris Pharmaceuticals 13 participants Est. completion 2014-11 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02082496
GLP-1 Response and Effect in Individuals With Obesity Causing Genetic Mutations
Not yet reported University of Copenhagen 50 participants Est. completion 2019-04 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02086227
Bioequivalence of Fresenius Kabi USA, LLC Glucagon for SC Injection Compared to Glucagon for Injection (Bedford Laboratories)
Not yet reported Fresenius Kabi USA, LLC 32 participants Est. completion 2013-06 1 site Stand-aloneOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02089256
Effect of Repeated Administration of Liraglutide on Insulinogenic Indices
Not yet reported University of Tartu 10 participants Est. completion 2015-03 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02092220
A Multicenter Study of Outpatient Automated Blood Glucose Control With a Bihormonal Bionic Pancreas
Not yet reported Massachusetts General Hospital 48 participants Est. completion 2016-12 4 sitesOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT02092896
Liraglutide as add-on to Insulin in Type 1 Diabetes
Not yet reported Hvidovre University Hospital 40 participants Est. completion 2014-10 1 siteOther conditions: Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02094183
The Interaction Between Appetite Hormones
Not yet reported University of Copenhagen 58 participants Est. completion 2014-04 2 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT02098395
The Efficacy and Safety of Liraglutide Adjunct to Insulin Treatment in Type 1 Diabetes
Not yet reported Novo Nordisk A/S 835 participants Est. completion 2015-04 120 sitesOther conditions: Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02099084
Short Bowel Syndrome and Teduglutide Versus Placebo
Not yet reported Mayo Clinic 8 participants Est. completion 2015-03 1 siteOther conditions: Short Bowel SyndromeView official trial listing → -
Completed NCT NCT02105324
The Summer Camp Study 2: Blood Glucose Control With a Bi-Hormonal Endocrine Pancreas
Not yet reported Massachusetts General Hospital 19 participants Est. completion 2014-08 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Withdrawn NCT NCT02109315
Vitamin C and Liraglutide Effects on Hypoglycemia-induced Oxidative Stress, Inflammation and Endothelial Dysfunction in Type 1 Diabetes.
Not yet reported Anna Cruceta Est. completion 2015-05 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02113332
Addition of Liraglutide to Patients With Type 2 Diabetes Treated With Multiple Daily Insulin Injections
Not yet reported Vastra Gotaland Region 124 participants Est. completion 2014-08 14 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT02127996
GLP-1 Loading During Elective Percutaneous Coronary Intervention
Not yet reported Papworth Hospital NHS Foundation Trust 193 participants Est. completion 2021-07 1 siteCardiovascular disease Other conditions: Angina Pectoris, Reperfusion Injury, Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT02128022
Cardioprotective Effects of GLP-1 and Their Mechanisms
Not yet reported Papworth Hospital NHS Foundation Trust 32 participants Est. completion 2016-03 1 siteOther conditions: Angina PectorisView official trial listing → -
Completed NCT NCT02129179
The Effect of Glucagon-Like Peptide-1 (GLP-1) on Pulmonary Vascular Resistance (PVR) in Patients With Heart Failure
Not yet reported Papworth Hospital NHS Foundation Trust 10 participants Est. completion 2016-12 1 siteHeart failureView official trial listing → -
Completed NCT NCT02140983
Effects of Liraglutide on Hippocampal Structure and Function in Aging Adults With Prediabetes
Not yet reported Stanford University 41 participants Est. completion 2017-02 1 siteOther conditions: Insulin Resistance, DementiaView official trial listing → -
Completed NCT NCT02147925
Efficacy Study of Liraglutide vs.Sitagliptin vs. Glargine on Liver Fat in T2DM Subjects
Not yet reported Sun Yat-sen University 75 participants Est. completion 2017-04 1 siteOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT02150707
The Differential Effects of Diabetes Therapy on Inflammation
University College Dublin 17 participants Est. completion 2015-12 1 siteChronic kidney diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT02163278
A Multiple Ascending Dose Phase I Study of DBPR108 in Healthy Male Subjects
Not yet reported National Health Research Institutes, Taiwan 32 participants Est. completion 2015-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02171130
Clinical Usability of Intranasal Glucagon in Treatment of Hypoglycemia
Not yet reported Eli Lilly and Company 129 participants Est. completion 2015-08 9 sitesOther conditions: Hypoglycemia, Diabetes Mellitus, Drug-Specific AntibodiesView official trial listing → -
Completed NCT NCT02180334
The Effect of Combination of Mosapride and DPP-4 Inhibitor on Plasma Concentration of Incretin Hormones
Not yet reported Seoul National University Hospital 12 participants Est. completion 2015-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02181127
Closed-Loop Glucagon Administration For Hypoglycemia Treatment
Not yet reported Massachusetts General Hospital 31 participants Est. completion 2017-04 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02187250
PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary Syndrome
Not yet reported University Medical Centre Ljubljana 45 participants Est. completion 2014-06 1 siteOther conditions: PCOS, ObesityView official trial listing → -
Completed NCT NCT02189694
Closed-loop Control of Overnight Glucose Levels (Artificial Pancreas) in Children With Type 1 Diabetes in a Diabetes Camp
Not yet reported Institut de Recherches Cliniques de Montreal 33 participants Est. completion 2014-08 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02192853
Correlation Between Plasma- and Endothelial DPP-4 Activity
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2014-03 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02198209
Liraglutide Actions on the Liver: Effects on Glucose Phosphorylation
Not yet reported Cedars-Sinai Medical Center Est. completion 2020-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02205528
A Study of Once-Daily NNC0090-2746 in Participants With Type 2 Diabetes Inadequately Controlled With Metformin
Not yet reported Novo Nordisk A/S 108 participants Est. completion 2015-09-15 20 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02207348
Investigating Bioequivalence Between Single-dose Liraglutide Administered Subcutaneously With Two Different Pen-injectors
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2014-09 1 siteOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT02219295
SEGATROM: Sensory and Gastrointestinal Impact of Taste Receptor Variants on Human Metabolism and Nutrition
Not yet reported German Institute of Human Nutrition 97 participants Est. completion 2014-09 1 siteOther conditions: Disorder of Glucose RegulationView official trial listing → -
Completed NCT NCT02229227
Safety and Efficacy of Albiglutide + Insulin Glargine Versus Insulin Lispro + Insulin Glargine Subjects With Type 2 Diabetes Mellitus
Not yet reported GlaxoSmithKline 814 participants Est. completion 2017-07-24 157 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02229240
Albiglutide Versus Placebo Added-on to Basal-Bolus Insulin Therapy in Subjects With Type 2 Diabetes Mellitus
Not yet reported GlaxoSmithKline Est. completion 2015-12Type 2 diabetesView official trial listing → -
Terminated NCT NCT02231658
Effects of Victoza® Versus Lyxumia® on Gastroesophageal Reflux, Gastric Emptying and Gastric Acid Secretion
Not yet reported Profil Institut für Stoffwechselforschung GmbH 109 participants Est. completion 2018-07-23 2 sitesOther conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT02232971
Treatment of Low Blood Sugar With Glucagon Among Patients With Type 1 Diabetes
Not yet reported Hvidovre University Hospital 8 participants Est. completion 2015-07 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02235584
Insulinotropic Effect of GLP-1 and GIP After Dexamethasone
Not yet reported Hvidovre University Hospital 19 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02235961
Investigate Safety, Tolerability and Pharmacokinetics for Single Doses of NNC9204-0530 Alone and in Combination With Liraglutide in Overweight to Obese But Otherwise Healthy Male Subjects
Not yet reported Novo Nordisk A/S 163 participants Est. completion 2016-07-06 1 siteOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Status unknown NCT NCT02236299
Diastolic RV EvAluation With Millar Catheter to Investigate the Effect of Glucagon-Like Peptide-1 (GLP-1) on Right Ventricular Function During Elective Coronary Angioplasty and Stenting
Not yet reported Papworth Hospital NHS Foundation Trust 30 participants 1 siteOther conditions: Right Coronary Artery Percutaneous Coronary Intervention, Right Ventricular Diastolic DysfunctionView official trial listing → -
Completed NCT NCT02237053
Effects of Glucagon Administration on Energy Expenditure
Not yet reported AdventHealth Translational Research Institute 6 participants Est. completion 2016-06 1 siteOther conditions: Hyperglucagonemia, ObesityView official trial listing → -
Completed NCT NCT02237521
The Effect of the Incretin Hormones on the Endocrine Pancreatic Function During Hyperglycemia in End-stage Renal Disease
Bo Feldt-Rasmussen 24 participants Est. completion 2016-04-28 1 siteOther conditions: End-stage Renal DiseaseView official trial listing → -
Completed NCT NCT02240043
Growth Hormone Evaluation in the Elderly People
Not yet reported Universidade Federal do Rio de Janeiro 48 participants Est. completion 2013-08Other conditions: AgingView official trial listing → -
Completed NCT NCT02241889
Three-way, Cross-over Closed-loop Exercise Study
Not yet reported Oregon Health and Science University 23 participants Est. completion 2015-09 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Terminated NCT NCT02244164
Pathophysiological Study of the Increase in Pancreatic Volume in Type 2 Diabetes Treatments.
Not yet reported Erasme University Hospital 5 participants Est. completion 2023-02-13 1 siteType 2 diabetes Other conditions: Incretinomimetics, PancreasView official trial listing → -
Completed NCT NCT02255266
Long-Term Effectiveness of Liraglutide for Treatment of Type 2 Diabetes in Daily Practice
Novo Nordisk A/S 1788 participants Est. completion 2015-11-16 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02256189
Sitagliptin and Glucagon Counterregulation
Not yet reported Lund University 28 participants Est. completion 2017-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02276196
Effect of LIXIsenatide on the Renal System
Not yet reported Amsterdam UMC, location VUmc 40 participants Est. completion 2016-04 1 siteChronic kidney disease Other conditions: Diabetes Mellitus, Glucagon-Like Peptide 1View official trial listing → -
Completed NCT NCT02280837
Is Glucagon-like Peptide-1 Insufficiency a Residual Risk in Coronary Artery Disease?
Sapporo Medical University 190 participants Est. completion 2020-12-29 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT02282254
Closed-loop Control of Overnight Glucose Levels (Artificial Pancreas) in Type 1 Diabètes Adults With Hypoglycemia Unawareness and Documented Nocturnal Hypoglycemia
Not yet reported Institut de Recherches Cliniques de Montreal 35 participants Est. completion 2016-07 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Withdrawn NCT NCT02284230
The Effect of Liraglutide in Patients With Prediabetes and Kidney Failure
Not yet reported Bo Feldt-Rasmussen Est. completion 2015-08 1 siteOther conditions: Kidney Failure, Chronic, Prediabetic StateView official trial listing → -
Completed NCT NCT02292290
Trial for People With Established Type 2 Diabetes During Ramadan
Not yet reported University of Leicester 99 participants Est. completion 2012-12 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02299050
Effect of Cycloset on Glycemic Control When Added to Glucagon-like Peptide 1 (GLP-1) Analogue Therapy
Not yet reported The University of Texas Health Science Center at San Antonio 23 participants Est. completion 2018-04-30 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02299388
To Evaluate the Effect of Liraglutide on Ambulatory Blood Pressure-A Pilot Study
Not yet reported Tulane University School of Medicine 11 participants Est. completion 2016-12 1 siteOther conditions: Diabetes Mellitus, Non-Insulin-Dependent, Hypertensive DiseaseView official trial listing → -
Completed NCT NCT02302976
GLP-1 Agonism for Blocking Cocaine Euphoria and Self-Administration
Not yet reported Yale University 13 participants Est. completion 2018-08-01 1 siteOther conditions: Cocaine DependenceView official trial listing → -
Completed NCT NCT02315001
Liraglutide to Improve corONary Haemodynamics During Exercise streSS
Not yet reported King's College London 26 participants Est. completion 2015-03 1 siteOther conditions: Ischaemic Heart Disease, Coronary Heart Disease, Chronic Stable AnginaView official trial listing → -
Completed NCT NCT02321878
Post-marketing Surveillance (Special Use-results Surveillance) on Use With Liraglutide (Victoza®)
Novo Nordisk A/S 1092 participants Est. completion 2017-06-16 5 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02324842
Effect of Combined Incretin-Based Therapy Plus Canagliflozin on Glycemic Control and the Compensatory Rise in Hepatic Glucose Production in Type 2 Diabetic Patients
Not yet reported The University of Texas Health Science Center at San Antonio 45 participants Est. completion 2019-03-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02337660
Involvement of Steatosis-induced Glucagon Resistance in Hyperglucagonaemia
Not yet reported University Hospital, Gentofte, Copenhagen 30 participants Est. completion 2016-01 1 siteOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Status unknown NCT NCT02344186
Effects of Liraglutide on ER Stress in Obese Patients With Type 2 Diabetes
Not yet reported Temple University 12 participants Est. completion 2023-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02351232
The Lira Pump Trial
Not yet reported, Not yet reported Hvidovre University Hospital 44 participants Est. completion 2016-10 2 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT02365740
Postprandial Blood Glucose Control and Gastric Emptying in Type 1 Diabetes: Pathogenetic Factors and Therapeutic Options
Not yet reported Federico II University 80 participants Est. completion 2016-11 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02367053
Single Ascending Doses of ZP4207 Administered in HV and in T1D to Evaluate Safety, Tolerability PKs and PDs of ZP4207 Compared to a Comparator
Not yet reported Zealand Pharma 111 participants Est. completion 2015-04 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02370745
Characterizing the Incretin Effect of Amino Acids and Defining GLP-1 Role on Skeletal Muscle
Not yet reported University of Nottingham 40 participants Est. completion 2018-03 1 siteOther conditions: SarcopeniaView official trial listing → -
Status unknown NCT NCT02372526
The Effect of Different Macronutrients on Gastrointestinal Hormone Secretion After Gastric Bypass Operation
Kirstine Nyvold Bojsen-Moeller 18 participants Est. completion 2017-06 1 siteOther conditions: Bariatric Surgery (Gastric Bypass), OverweightView official trial listing → -
Withdrawn NCT NCT02379299
DiaCon Dual-Hormone Closed-Loop Glucose Control
Not yet reported, Not yet reported Hvidovre University Hospital 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02381249
The Effect of Satiety Gut Hormone Modulation on Appetitive Drive After Upper Gastrointestinal Surgery
Not yet reported St. James's Hospital, Ireland 40 participants Est. completion 2018-03 2 sitesOther conditions: Esophageal Neoplasms, Stomach Neoplasms, Weight Loss, Malnutrition, Pancreatic Neoplasms, Duodenal NeoplasmsView official trial listing → -
Completed NCT NCT02385617
Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer
Not yet reported St. James's Hospital, Ireland 20 participants Est. completion 2017-12 2 sitesOther conditions: Esophageal Neoplasms, Stomach Neoplasms, Weight Loss, MalnutritionView official trial listing → -
Completed NCT NCT02385630
Longitudinal Assessment of Gut Hormone Secretion Following Upper Gastrointestinal Surgery for Cancer
Not yet reported St. James's Hospital, Ireland 40 participants Est. completion 2018-07 1 siteOther conditions: Esophageal Neoplasms, Stomach Neoplasms, Weight Loss, MalnutritionView official trial listing → -
Completed NCT NCT02397265
Clinical Assessment of a Closed-loop System With Glucagon, Exercise and Mixed Meals
Not yet reported Imperial College London 24 participants Est. completion 2015-07-22 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02398383
Role of Glucagon In Glucose Control in Cystic Fibrosis Related Diabetes
Not yet reported Yale University 7 participants Est. completion 2017-06-22 1 siteOther conditions: Cystic Fibrosis, Cystic Fibrosis Related DiabetesView official trial listing → -
Completed NCT NCT02402933
Clinical Usability of Nasal Glucagon in Treatment of Hypoglycemia in Children and Adolescents
Not yet reported Eli Lilly and Company 26 participants Est. completion 2015-08 3 sitesOther conditions: Hypoglycemia, Diabetes MellitusView official trial listing → -
Completed NCT NCT02403284
The Effect of Liraglutide on Dietary Lipid Induced Insulin Resistance in Humans
Not yet reported Phoenix VA Health Care System 97 participants Est. completion 2023-11-01 1 siteOther conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT02403648
Pharmacokinetics and Pharmacodynamics of BIOD-961 vs. Marketed Glucagons
Not yet reported Biodel 15 participantsOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02404376
COMBinAtion Therapy in Myocardial Infarction: The COMBAT-MI Trial
Not yet reported Hospital Universitari Vall d'Hebron Research Institute 378 participants Est. completion 2020-06 6 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT02408705
Investigating the Effect of Liraglutide on the Endogenous Glucose Production During in Tye 1 Diabetes Subjects
Not yet reported Medical University of Graz 14 participants Est. completion 2016-05 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02411578
Mini-Dose Glucagon to Treat Non-Severe Hypoglycemia
Not yet reported Jaeb Center for Health Research 26 participants Est. completion 2016-05 5 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02416765
Closed-loop Control of Postprandial Glucose Levels in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 15 participants Est. completion 2015-10 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Terminated NCT NCT02417103
Pretreatment of Patients Expecting Bariatric Surgery With the GLP-1 Analogon Liraglutid
Not yet reported Universitätsklinikum Hamburg-Eppendorf 2 participants Est. completion 2016-12 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02423824
Cognitive Dysfunction and Glucagon-like Peptide-1 Agonists
Not yet reported University Health Network, Toronto 21 participants Est. completion 2016-05 1 siteOther conditions: Bipolar Disorder, Major Depressive DisorderView official trial listing → -
Completed NCT NCT02423980
G-Pen™ for Hypoglycemia Rescue in T1D Patients
Not yet reported Xeris Pharmaceuticals 7 participants Est. completion 2015-06 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02443155
A Clinical Proof-of-principle Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of NNC0114-0006 and Liraglutide on Preservation of Beta-cell Function
Not yet reported Novo Nordisk A/S 308 participants Est. completion 2019-02-27 108 sitesOther conditions: Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02446834
Research of Intensive Lifestyle Intervention for PCOS Patients With IGT
Not yet reported RenJi Hospital 40 participants Est. completion 2018-04 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02453711
Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus
Not yet reported Novo Nordisk A/S 957 participants Est. completion 2017-04-12 74 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT02456428
Incretin-based Drugs and the Risk of Heart Failure
Canadian Network for Observational Drug Effect Studies, CNODES 1499650 participants Est. completion 2015-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02459938
Safety and Efficacy of ZP-Glucagon to Injectable Glucagon for Hypoglycemia
Not yet reported Zosano Pharma Corporation 16 participants Est. completion 2015-10 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02461589
Dose-finding of Semaglutide Administered Subcutaneously Once Daily Versus Placebo and Liraglutide in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 706 participants Est. completion 2016-10-13 150 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02465515
Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus
Not yet reported GlaxoSmithKline 9463 participants Est. completion 2018-03-14 607 sitesOther conditions: Diabetes MellitusView official trial listing → -
Withdrawn NCT NCT02472717
Psoriatic Arthritis Treated With Liraglutide Therapy: a QUality of Life and Efficacy Study
Not yet reported University Health Network, Toronto Est. completion 2016-10 1 sitePrediabetesType 2 diabetes Other conditions: Psoriatic Arthritis, PsoriasisView official trial listing → -
Completed NCT NCT02473809
The Effect of Liraglutide on Bone Turnover, Bone Mass and Bone Cell Function
Not yet reported University of Aarhus 60 participants Est. completion 2017-10 1 siteOther conditions: Diabetes Complications, OsteoporosisView official trial listing → -
Completed NCT NCT02475070
Vildagliptin Versus Dapagliflozin on Glucagon
Not yet reported Lund University 28 participants Est. completion 2017-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02475421
Hyperglucagonaemia in Patients With Type 2 Diabetes - Role of Glucagon Clearance
Not yet reported University Hospital, Gentofte, Copenhagen 32 participants Est. completion 2017-01 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02475499
Incretin-based Drugs and Pancreatic Cancer
Canadian Network for Observational Drug Effect Studies, CNODES 886172 participants Est. completion 2015-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02476760
Incretin-based Drugs and Acute Pancreatitis
Canadian Network for Observational Drug Effect Studies, CNODES 1417914 participants Est. completion 2015-04 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02480985
The PIT-TBI Pilot Study
Not yet reported CHU de Quebec-Universite Laval 70 participants Est. completion 2018-03 5 sitesOther conditions: Pituitary Disorders, Traumatic Brain InjuryView official trial listing → -
Completed NCT NCT02483299
Liraglutide as Add on Therapy on Metformin in Women With Polycystic Ovary Syndrome
Not yet reported University Medical Centre Ljubljana 40 participants Est. completion 2015-04 1 siteOther conditions: PCOS, ObesityView official trial listing → -
Completed NCT NCT02488057
Improving Beta Cell Function in Mexican American Women With Prediabetes
Not yet reported Ohio State University 360 participants Est. completion 2019-03 4 sitesPrediabetesView official trial listing → -
Completed NCT NCT02490085
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 24 Hours in Adults With Type 2 Diabetes Under Intensive Insulin Therapy
Not yet reported Institut de Recherches Cliniques de Montreal 15 participants Est. completion 2018-09 2 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02490098
Closed-loop Control of Postprandial Glucose Levels in Children and Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal Est. completion 2018-07 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT02490176
Effects of Glucagon Like Peptide-1 on Haemodynamic Parameters
Not yet reported Chinese PLA General Hospital 50 participants Est. completion 2016-07 1 siteHeart failureView official trial listing → -
Terminated NCT NCT02492763
A Preliminary Study of the Efficacy and Safety of MK-8521 for Type 2 Diabetes (MK-8521-004)
Not yet reported Merck Sharp & Dohme LLC 176 participants Est. completion 2017-04-18 Stand-aloneOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT02497859
Breakfast Intake and Satiety Hormones
Not yet reported Texas Tech University 20 participants Est. completion 2016-05 1 siteOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT02501850
The Effect of the GLP-1 Receptor Agonists on Blood Levels of Lipoprotein (a)
Not yet reported Hospital Universitari Vall d'Hebron Research Institute 40 participants Est. completion 2015-10 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02503943
Effects of Incretin on the Blood Pressure and Lipid in Patients With Overweight or Obese Diabetes
Not yet reported Third Affiliated Hospital of Third Military Medical University 90 participants Est. completion 2016-09Type 2 diabetes Other conditions: Overweight, Obesity, Masked HypertensionView official trial listing → -
Completed NCT NCT02505334
A Trial Comparing the Efficacy and Safety of Liraglutide 1.8 mg/Day to Liraglutide 0.9 mg/Day in Japanese Subjects With Type 2 Diabetes Mellitus.
Not yet reported Novo Nordisk A/S 635 participants Est. completion 2017-11-09 47 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT02507128
Effects of Glucagon Like Peptide-1 on No-reflow
Not yet reported Chen Wei Ren, MD 190 participants Est. completion 2016-07 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT02509065
The Set-Point Study: Evaluating Effects of Changing Glucose Target on Bionic Pancreas Performance
Not yet reported Massachusetts General Hospital 24 participants Est. completion 2017-12 1 siteType 2 diabetes Other conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02516150
Effect of Ethanol Intoxication on the Anti-Hypoglycemic Action of Glucagon
Not yet reported Massachusetts General Hospital 26 participants Est. completion 2017-06 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02516657
Liraglutide in Adolescents With Type 1 Diabetes
Not yet reported University at Buffalo 5 participants Est. completion 2023-08-03 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02518945
Dapagliflozin As Additional Treatment To Liraglutide And Insulin In Patients With Type 1 Diabetes
Not yet reported University at Buffalo 26 participants Est. completion 2016-04 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02527200
Effect of Liraglutide for Weight Management in Paediatric Subjects With Prader-Willi Syndrome
Not yet reported Novo Nordisk A/S 56 participants Est. completion 2020-11-19 32 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT02527993
Treatment of Hypoglycemia Following Gastric Bypass Surgery
Not yet reported Zealand University Hospital 11 participants Est. completion 2017-04-08Other conditions: Hypoglycemia, Obesity, SurgeryView official trial listing → -
Status unknown NCT NCT02535299
Par-4 and Telomere-telomerase System in Type 2 Diabetes Patients Who Received GLP-1 or Metformin Treatment
Not yet reported Third Military Medical University 200 participants Est. completion 2019-12 1 siteOther conditions: GLP-1;Metformin;Telomere-telomerase System;Par-4View official trial listing → -
Completed NCT NCT02537834
Tofogliflozin GLP-1 Analogue Combination Trial
Not yet reported Kowa Company, Ltd. 65 participants Est. completion 2017-10 11 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02545738
Antiproteinuric Effects of Liraglutide Treatment
Not yet reported Steno Diabetes Center Copenhagen 32 participants Est. completion 2016-05 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT02550548
Incretin Action in Physiology and Diabetes
Not yet reported David D'Alessio, M.D. 39 participants Est. completion 2021-04-16 1 siteOther conditions: Insulin SecretionView official trial listing → -
Status unknown NCT NCT02560376
68Ga-NOTA-exendin-4 PET/CT for the Localization of Insulinoma and Diagnosis of Nesidioblastosis
Not yet reported Peking Union Medical College Hospital 100 participants Est. completion 2016-12 1 siteOther conditions: Insulinoma, NesidioblastosisView official trial listing → -
Status unknown NCT NCT02577848
GLP-1 on Non-ST-Segment Elevation Myocardial Infarction
Not yet reported Chinese PLA General Hospital 90 participants Est. completion 2016-10 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT02578498
Glucagon Efficiency After High and Low Carbohydrate Diet
Not yet reported Hvidovre University Hospital 10 participants Est. completion 2016-07 1 siteOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Status unknown NCT NCT02584582
The Effect of GLP-1 on Postprandial Glucagon Secretion Independent of The Gastric Emptying Rate
Not yet reported, Not yet reported Hvidovre University Hospital 10 participantsOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02589626
Long-term Safety and Efficacy of Empagliflozin as Add on to GLP-1 RA
Not yet reported Boehringer Ingelheim 65 participants Est. completion 2017-06-02 16 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02591849
GLP-1 Effects on Insulin and Glucagon in PTDM
Not yet reported Oslo University Hospital 24 participants Est. completion 2015-03 1 siteOther conditions: Post-transplant Diabetes MellitusView official trial listing → -
Completed NCT NCT02592421
SGLT2 Inhibition and Stimulation of Endogenous Glucose Production: Protocol 2
Not yet reported The University of Texas Health Science Center at San Antonio 30 participants Est. completion 2019-10-31 1 siteOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT02598791
GIP/GLP-1 Co-Activity in Subjects With Obesity: Lowering of Food Intake
Not yet reported University Hospital, Gentofte, Copenhagen 18 participants Est. completion 2016-06-20 1 siteType 2 diabetes Other conditions: Obesity, AdiposityView official trial listing → -
Completed NCT NCT02602600
Glucagon-like Peptide-1 and Coronary Microvascular Dysfunction in Women With Angina Pectoris and no Coronary Stenosis
Not yet reported Eva Prescott 33 participants Est. completion 2017-04-18 1 siteOther conditions: Microvascular AnginaView official trial listing → -
Completed NCT NCT02607306
A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Japanese Subjects With Type 2 Diabetes Mellitus.
Not yet reported Novo Nordisk A/S 819 participants Est. completion 2017-12-22 76 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT02611232
Incretin-based Therapy in Preclinical Type 1 Diabetes in Adults
Not yet reported University of Oulu 42 participants Est. completion 2024-06 3 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02616003
Preoperative Condition in Giant Obese Patients
Not yet reported Sana Klinikum Offenbach 50 participants Est. completion 2018-04 1 siteOther conditions: Morbid Obesity, Bariatric Surgery CandidateView official trial listing → -
Completed NCT NCT02617654
Liraglutide Effect on Beta-cell Function in C-peptide Positive Type 1 Diabetes
Not yet reported Per-Ola Carlsson 18 participants Est. completion 2020-09 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02621489
Effects on Re-endothelialisation With Bydureon Treatment in Type 2 Diabetes Subjects
Not yet reported Karolinska Institutet 38 participants Est. completion 2022-10 1 siteOther conditions: Atherosclerosis, Diabetes, RestenosisView official trial listing → -
Completed NCT NCT02624817
Long-Term Sulfonylurea Response in KCNJ11 Neonatal Diabetes
Not yet reported Haukeland University Hospital 90 participants Est. completion 2016-08 1 siteOther conditions: Permanent Neonatal Diabetes MellitusView official trial listing → -
Status unknown NCT NCT02624830
Long-Term Sulfonylurea Response in ABCC8 Neonatal Diabetes (SuResponsSUR)
Not yet reported Haukeland University Hospital 30 participants Est. completion 2020-02 1 siteOther conditions: Permanent Neonatal Diabetes MellitusView official trial listing → -
Completed NCT NCT02625636
A Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Doses of SAR438544 in Comparison to Placebo and Glucagon in Healthy Subjects and Type 1 Diabetes Mellitus Patients
Not yet reported Sanofi 20 participants Est. completion 2016-02 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02626936
Safety of Overestimation of a Meal Insulin Bolus in the Context of Dual-hormone Closed-loop Operation
Not yet reported Institut de Recherches Cliniques de Montreal 10 participants Est. completion 2016-06 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Withdrawn NCT NCT02635243
A Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of a Single Dose of SAR438544 in Comparison to Glucagon in Type 1 Diabetes Mellitus Patients Under Induced Hypoglycemia
Not yet reported Sanofi Est. completion 2016-11Other conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02635386
EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)
Not yet reported Woman's 119 participants Est. completion 2020-10-09 1 siteOther conditions: Polycystic Ovary Syndrome, ObesityView official trial listing → -
Status unknown NCT NCT02637388
Effects of Beta-glucan on Energy Intake and Satiety
Not yet reported Queen Margaret University 36 participants Est. completion 2016-12 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02638805
Study of the Safety and Tolerability of Switching to ITCA 650 in Patients With Type 2 Diabetes Receiving Liraglutide
Not yet reported Intarcia Therapeutics 136 participants Est. completion 2017-10 36 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02639130
GLP-1 Mediating DPP-4 Inhibition in Type 2 Diabetes
Not yet reported Diabeteszentrum Bad Lauterberg im Harz 67 participants Est. completion 2010-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02647944
Pilot Study of the Effect of Liraglutide on Weight Loss and Gastric Functions in Obesity
Not yet reported Mayo Clinic 40 participants Est. completion 2016-12-30 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02650206
Effect of Liraglutide (Victoza) on Inflammation in Human Adipose Tissue and Blood
Not yet reported Stanford University 56 participants Est. completion 2019-09-27 1 siteType 2 diabetes Other conditions: Diabetes Mellitus, Type II, Diabetes Mellitus, Adult-Onset, InflammationView official trial listing → -
Status unknown NCT NCT02650596
Effects of GLP-1 on Chronic Heart Failure
Not yet reported Shi Yang 68 participants Est. completion 2018-02 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT02654665
Comparing Effects of Liraglutide and Bariatric Surgery on Weight Loss, Liver Function, Body Composition, Insulin Resistance, Endothelial Function and Biomarkers of Non-alcoholic Steatohepatitis (NASH) in Obese Asian Adults
Not yet reported Changi General Hospital 36 participants Est. completion 2018-12 1 siteMASLDMASH Other conditions: Weight LossView official trial listing → -
Completed NCT NCT02655770
Effect of Liraglutide on Diastolic Dysfunction on Cardiac MRI in Type 2 Diabetes Patients
Not yet reported Copenhagen University Hospital, Rigshospitalet 40 participants Est. completion 2019-12 1 siteType 2 diabetes Other conditions: Diastolic Dysfunction, Cardiac MRI, Myocardial PerfusionView official trial listing → -
Completed NCT NCT02656069
Safety and Efficacy of G-Pen Compared to Lilly Glucagon for Hypoglycemia Rescue in Adult Type 1 Diabetics
Not yet reported Xeris Pharmaceuticals 80 participants Est. completion 2017-09-25 7 sitesOther conditions: Hypoglycemia, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02660008
Single Doses of ZP4207 Adm. sc to Hypoglycemic TD1 pt. to Describe the PK and PD of ZP4207 as Comp. to Marketed Glucagon
Not yet reported Zealand Pharma 81 participants Est. completion 2016-06 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02660047
Effect of Liraglutide on Cardiovascular Endpoints in Diabetes Mellitus Type 2 Patients of South Asian Descent
Not yet reported Leiden University Medical Center 51 participants Est. completion 2018-03-09 1 siteType 2 diabetesMetabolic syndromeCardiovascular disease Other conditions: Diastolic Dysfunction, Fatty LiverView official trial listing → -
Completed NCT NCT02660242
The Use of Mini-dose Glucagon to Prevent Exercise-induced Hypoglycemia in Type 1 Diabetes
Not yet reported Jaeb Center for Health Research 16 participants Est. completion 2017-02-15 2 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02662400
Assessment of Insulin Sensitivity and β Cell Function by Clamps Studies
Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 7 participants Est. completion 2016-12Other conditions: Diabetes Mellitus, Non-Insulin-DependentView official trial listing → -
Completed NCT NCT02663661
Insulin-Glucose-Glucagon Network: Defining a Type 1 Diabetes Progression Index
Not yet reported University of Virginia 73 participants Est. completion 2019-06-30 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02664441
Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic Obesity
Not yet reported Seattle Children's Hospital 42 participants Est. completion 2020-07-31 3 sitesOther conditions: Hypothalamic ObesityView official trial listing → -
Completed NCT NCT02665715
Can Postprandial Reactive Hypoglycaemia be Reduced in Patients After Roux-en-Y Gastric Bypass With a Low Carbohydrate Diet?
Not yet reported Amirsalar Samkani 10 participants Est. completion 2016-06 1 siteOther conditions: Bariatric Surgery (Gastric Bypass)View official trial listing → -
Completed NCT NCT02669524
Dissection of the Gastrointestinal-mediated Glucose Disposal and Incretin Defect in Patients With Type 2 Diabetes
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2016-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02673554
The Reduced Insulinotropic Effect of a Continuous Infusion Relative to a Bolus Injection of GIP
Not yet reported Diabeteszentrum Bad Lauterberg im Harz 30 participantsType 2 diabetesView official trial listing → -
Status unknown NCT NCT02673931
GLP-1 and Hyperoxia for Organ Protection in Heart Surgery
Not yet reported Copenhagen University Hospital, Rigshospitalet 1400 participants Est. completion 2024-09 1 siteCardiovascular disease Other conditions: Coronary Disease, Shock, Cardiogenic, Renal Failure, Brain Injury, Aortic Valve DiseaseView official trial listing → -
Terminated NCT NCT02674893
Effect of Victoza on Dietary Preferences and Habit in Patients With Type 2 Diabetes
Not yet reported Centre Hospitalier Universitaire Dijon 48 participants Est. completion 2016-08-31 1 siteType 2 diabetes Other conditions: OverweightView official trial listing → -
Completed NCT NCT02683187
DPP4 Inhibition & Beta Cell Function
Not yet reported David D'Alessio, M.D. 40 participants Est. completion 2018-03-16 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT02686177
Effect of GLP-1 on Angiogenesis
Not yet reported Assistance Publique - Hôpitaux de Paris 50 participants Est. completion 2021-05-28 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02692040
Study of the Gut Hormone Analogue G3215 in Adult Subjects
Not yet reported Imperial College London 90 participants Est. completion 2019-01 1 siteOther conditions: Diabetes Mellitus, ObesityView official trial listing → -
Completed NCT NCT02696148
A Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Liraglutide in Obese Children Aged 7 to 11 Years
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2017-04-13 9 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Terminated NCT NCT02701257
The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic Pancreas
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2018-05 1 siteOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT02717858
A Trial to Assess the Effects of Liraglutide on Gallbladder Emptying in Overweight and Obese Subjects.
Not yet reported Novo Nordisk A/S 52 participants Est. completion 2017-02-27 1 siteOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Status unknown NCT NCT02718950
Influence of Liraglutide, a GLP-1 Receptor Agonist, on Brown Adipose Tissue (BAT) Activity in Humans
Not yet reported University of Campinas, Brazil 20 participants Est. completion 2017-04Type 2 diabetes Other conditions: ObesityView official trial listing → -
Terminated NCT NCT02721888
Effect of Liraglutide on Fatty Liver Content and Lipoprotein Metabolism
Not yet reported Centre Hospitalier Universitaire Dijon 127 participants 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02725502
Incretin Axis in Type 1 Diabetes Mellitus
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 20 participants Est. completion 2016-05 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02730377
Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1991 participants Est. completion 2019-08-12 232 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02731664
GLP-1 Inhibits Prandial Antro-duodeno-jejunal Motility in Humans
Not yet reported Uppsala University 12 participants Est. completion 2017-08 1 siteOther conditions: Functional Gastrointestinal DisordersView official trial listing → -
Completed NCT NCT02733588
Delivery of G-Pump™ (Glucagon Infusion) From an OmniPod® to Prevent Hypoglycemia in Post-Bariatric Surgery Patients
Not yet reported Xeris Pharmaceuticals 8 participants Est. completion 2017-06-01 1 siteOther conditions: Hypoglycemia, Complications of Bariatric ProceduresView official trial listing → -
Completed NCT NCT02735031
Exenatide and Impaired Hypoglycaemic Awareness in Type 1 Diabetes
Not yet reported, Not yet reported Radboud University Medical Center 10 participants Est. completion 2018-04-09 1 siteOther conditions: Diabetes Mellitus, Type 1, HypoglycemiaView official trial listing → -
Completed NCT NCT02738151
Efficacy and Safety of Toujeo® Versus Tresiba® in Insulin-Naive Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Oral Antihyperglycemic Drug(s) ± GLP-1 Receptor Agonist
Not yet reported Sanofi 929 participants Est. completion 2017-08-15 158 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02740829
Assessment of Intranasal Glucagon on Endogenous Glucose Production
Not yet reported University Health Network, Toronto 10 participants Est. completion 2016-03Other conditions: DiabetesView official trial listing → -
Terminated NCT NCT02743598
Liraglutide for HIV-associated Neurocognitive Disorder
Not yet reported Temple University 4 participants Est. completion 2018-09 1 siteType 2 diabetesMetabolic syndrome Other conditions: HIV Infection, Obesity, OverweightView official trial listing → -
Completed NCT NCT02746757
Glucagon Like Peptide-1 in Remote Ischemic Conditioning
Not yet reported Karolinska Institutet 12 participants Est. completion 2018-01 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02748369
In Vivo Assessment of Cellular Metabolism in Humans
Not yet reported K. Sreekumaran Nair 17 participants Est. completion 2017-03-02 1 siteOther conditions: Normal Cellular MetabolismView official trial listing → -
Completed NCT NCT02749032
Feed-Back Suppression of Meal-Induced Glucagon-like Peptide 1 (GLP-1) Secretion
Not yet reported Michael A. Nauck 24 participants 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT02750930
Extension to Study 200952 to Evaluate the Long-term Safety, Tolerability and Pharmacodynamics of Albiglutide Liquid Drug Product in Type 2 Diabetes Mellitus Subjects
Not yet reported GlaxoSmithKline 8 participants Est. completion 2017-03-21 27 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02759107
A Study of Tirzepatide (LY3298176) in Healthy Participants and Participants With Type 2 Diabetes (T2DM)
Not yet reported Eli Lilly and Company 142 participants Est. completion 2017-06-26 2 sitesType 2 diabetes Other conditions: HealthyView official trial listing → -
Completed NCT NCT02765399
The Effect of Liraglutide Treatment on Postprandial Chylomicron and VLDL Kinetics, Liver Fat and de Novo Lipogenesis
Not yet reported Helsinki University Central Hospital 23 participants Est. completion 2019-02-28 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02773355
Timely Detection of Treatment Emergent Serious and Non-serious Adverse Events for Saxenda® in Mexican Patients
Novo Nordisk A/S 27 participants Est. completion 2022-02-28 14 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT02777073
Effects of Single Doses of Liraglutide and Dapagliflozin on Ketogenesis in Type 1 Diabetes
Not yet reported University at Buffalo 43 participants Est. completion 2016-12-31 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02778100
A Study of Nasal Glucagon in Participants With a Common Cold
Not yet reported Eli Lilly and Company 36 participants Est. completion 2013-04 1 siteOther conditions: Common ColdView official trial listing → -
Completed NCT NCT02778113
A Study of Glucagon Administered in Different Forms and Routes to Healthy Adults
Not yet reported Eli Lilly and Company 16 participants Est. completion 2011-11 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02783196
Effect of Liraglutide on Clock Genes
Not yet reported Tel Aviv University 14 participants Est. completion 2017-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02787551
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period
Not yet reported Sanofi 514 participants Est. completion 2018-11-17 124 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02792400
The Role of Glucagon in the Effects of Dipeptidyl Peptidase-4 Inhibitors and Sodium-glucose Co-transporter-2 Inhibitors
Not yet reported University Hospital, Gentofte, Copenhagen 24 participants Est. completion 2018-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02796950
The Effect of Acipimox on GLP (Glucagon-like Peptide)-1 Secretion
Not yet reported University of Aarhus 8 participants Est. completion 2017-01-20 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02798250
Safety of Overestimation of a Meal Insulin Bolus in the Context of Dual-hormone Closed-loop Operation - Part 2
Not yet reported Institut de Recherches Cliniques de Montreal 11 participants Est. completion 2017-03 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Terminated NCT NCT02802514
A Study Comparing the Effect of Albiglutide With Exenatide on Regional Brain Activity Related to Nausea in Healthy Subjects
Not yet reported GlaxoSmithKline 5 participants Est. completion 2017-09-07 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT02806960
A Study of Single and Repeated Doses of Glucagon Administered to Participants With Diabetes
Not yet reported Eli Lilly and Company 12 participants Est. completion 2014-08 1 siteType 2 diabetes Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02806973
A Study of Single or Repeated Doses of Glucagon in Participants With Diabetes
Not yet reported Eli Lilly and Company 32 participants Est. completion 2015-04 1 siteType 2 diabetes Other conditions: Diabetes Mellitus, Type 1View official trial listing → -
Active, not recruiting NCT NCT02817659
To Determine Tolerability to Glucagon Infusion in Obese Subjects
Not yet reported AdventHealth Translational Research Institute 20 participants Est. completion 2026-12 1 siteOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT02829502
The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Stroke
Not yet reported Christina Kruuse 30 participants Est. completion 2023-11 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT02830048
Low dosE GlibENclamide in Diabetes Part A
Not yet reported University of Oxford 16 participants Est. completion 2017-03-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02832999
Short Term Effect of Liraglutide Versus Vildagliptine on Insulin Secretion and Insulin Sensitivity in Type 2 Diabetes
Not yet reported Yaounde Central Hospital 14 participants Est. completion 2016-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02838589
The Effect of GLP-1 Receptor Agonist on Cerebral Blood Flow Velocity in Non-stroke Volunteers
Not yet reported Christina Kruuse 30 participants Est. completion 2017-02 1 siteCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT02846857
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 15 Weeks in Adolescents and Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de MontrealOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02857764
Sodium-glucose Co-transporter 2 (SGLT2) Inhibitor Risk of Below-Knee Lower Extremity Amputation: A Retrospective Cohort Study Using a Large Claims Database in the United States
Janssen Research & Development, LLC 127690 participants Est. completion 2017-06-30Type 2 diabetesView official trial listing → -
Completed NCT NCT02860923
Efficacy and Safety of Exenatide in the Treatment of Hypothalamic Obesity After Craniopharyngioma Therapy
Not yet reported University Hospital, Bordeaux 42 participants Est. completion 2018-09-30 11 sitesOther conditions: Craniopharyngiomas, Hypothalamic ObesityView official trial listing → -
Completed NCT NCT02862730
Four Way Crossover Closed Loop With Exercise Detection
Not yet reported Oregon Health and Science University 25 participants Est. completion 2018-01-31 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02863419
Efficacy and Safety of Oral Semaglutide Versus Liraglutide and Versus Placebo in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 711 participants Est. completion 2018-03-30 108 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02870231
Investigating Safety, Tolerability, PK and PD for Multiple Doses of NNC9204-0530 in Combination With Liraglutide in Male and Female Subjects Being Overweight or With Obesity
Not yet reported Novo Nordisk A/S 187 participants Est. completion 2017-09-03 2 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Active, not recruiting NCT NCT02879409
HbA1c Variability in Type II Diabetes
Not yet reported Weill Cornell Medical College in Qatar 150 participants Est. completion 2026-10-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02879955
Carbohydrates and Gut Hormones After Gastric Bypass Surgery
Not yet reported Hvidovre University Hospital 20 participants Est. completion 2017-06 1 siteOther conditions: OverweightView official trial listing → -
Completed NCT NCT02881060
The Late Effects of Ethanol Intake on the Glucose Response to Subcutaneous Glucagon in Type 1 Diabetes
Not yet reported Hvidovre University Hospital 12 participants Est. completion 2017-01-26 1 siteOther conditions: Hypoglycemia, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02882737
The Impact of Subcutaneous Glucagon Before, During and After Exercise a Study in Patients With Type 1 Diabetes Mellitus
Not yet reported Hvidovre University Hospital 14 participants Est. completion 2017-07-11 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT02887625
Exenatide Plus Pioglitazone Versus Insulin in Poorly Controlled T2DM
Not yet reported Dr. Muhammad Abdulghani 410 participants Est. completion 2017-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02889510
Study to Assess the Efficacy of Liraglutide in Patients With Type 2 Diabetes Mellitus
Not yet reported Lecube, Albert, M.D. 76 participants Est. completion 2019-12-16 6 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT02891954
Genetics of Response to Canagliflozin
Not yet reported University of Maryland, Baltimore 700 participants Est. completion 2026-12-25Type 2 diabetesView official trial listing → -
Completed NCT NCT02895672
GLP-1/Basal Insulin Combination Therapy
Albany College of Pharmacy and Health Sciences 150 participants Est. completion 2016-12Type 2 diabetesView official trial listing → -
Completed NCT NCT02898506
Incretin-based Therapy in Late Preclinical Type 1 Diabetes
Not yet reported University of Oulu 13 participants Est. completion 2021-06 4 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02905864
Liraglutide 3 mg for Knee Osteoarthritis
Not yet reported Henrik Gudbergsen 150 participants Est. completion 2019-03 1 siteOsteoarthritis Other conditions: ObesityView official trial listing → -
Completed NCT NCT02908087
Incretin-based Therapy in Early Diagnosed Type 1 Diabetes
Not yet reported University of Oulu 13 participants Est. completion 2021-05 4 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT02909933
Low Dose Liraglutide and Metformin vs. High Dose Liraglutide Alone in Treatment of Obesity
Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2015-10 1 siteOther conditions: Polycystic Ovary Syndrome, ObesityView official trial listing → -
Completed NCT NCT02910518
A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus
Not yet reported Sanofi 44 participants Est. completion 2017-05-03 1 siteOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02910570
Changes in Skin Autoflouresence Following Weight Loss and Maintenance Using Liraglutide in Knee Osteoarthritis
Not yet reported Parker Research Institute 150 participants Est. completion 2019-03 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT02911818
Lifestyle Modification and Liraglutide
Not yet reported University of Pennsylvania 150 participants Est. completion 2018-12 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02916251
ZP4207(Dasiglucagon) Administered to T1D Patients to Assess the PK and PD Compared to Marketed Glucagon
Not yet reported Zealand Pharma 38 participants Est. completion 2017-04-05 1 siteOther conditions: Diabetes Mellitus Type 1View official trial listing → -
Completed NCT NCT02918279
Effect of Liraglutide for Weight Management in Pubertal Adolescent Subjects With Obesity
Not yet reported Novo Nordisk A/S 251 participants Est. completion 2019-08-08 33 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Withdrawn NCT NCT02920190
Antigen-Lipid-Driven Monoclonal Gammopathies Targeting Epicardial Fat
Not yet reported University of Miami Est. completion 2021-12-31Other conditions: Monoclonal Gammopathies, Overweight, ObesityView official trial listing → -
Completed NCT NCT02928614
Biomarkers in Obese Patients With Knee Osteoarthritis; Weight Maintenance
Not yet reported Henrik Gudbergsen 150 participants Est. completion 2019-03 1 siteOsteoarthritis Other conditions: ObesityView official trial listing → -
Completed NCT NCT02928679
Multi-parametric Imaging of the Knee in Obese Patients With Knee Osteoarthritis; Weight Maintenance
Not yet reported Henrik Gudbergsen 150 participants Est. completion 2019-03-20 1 siteOsteoarthritis Other conditions: ObesityView official trial listing → -
Status unknown NCT NCT02930265
Clinical Study of Liraglutide in Improving Cardiac Function for Patients With Ischemic Cardiomyopathy
Not yet reported Chinese PLA General Hospital 400 participants Est. completion 2018-03 1 siteOther conditions: Ischemic CardiomyopathyView official trial listing → -
Completed NCT NCT02931383
Ultrasound of the Knee in Obese Patients With Knee Osteoarthritis; Weight Maintenance
Not yet reported Henrik Gudbergsen 150 participants Est. completion 2019-03 1 siteOsteoarthritis Other conditions: ObesityView official trial listing → -
Completed NCT NCT02937558
CSI-Glucagon for Prevention of Hypoglycemia in Children With Congenital Hyperinsulinism
Not yet reported Xeris Pharmaceuticals 5 participants Est. completion 2018-10 5 sitesOther conditions: Congenital HyperinsulinismView official trial listing → -
Status unknown NCT NCT02940184
GLP-1 Signaling in Truncally Vagotomized Subjects
Not yet reported University of Copenhagen 24 participants Est. completion 2018-10 1 siteOther conditions: PhysiologyView official trial listing → -
Status unknown NCT NCT02944110
Delineation of the Diabetogenic Role of Extrapancreatic Glucagon in Totally Pancreatectomised Patients Using Glucagon Receptor Antagonism
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2021-07Other conditions: Diabetes After Total PancreatectomyView official trial listing → -
Active, not recruiting NCT NCT02944500
Saxenda: Underlying Mechanisms and Clinical Outcomes
Not yet reported Beth Israel Deaconess Medical Center 28 participants Est. completion 2027-06 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02953665
Safety and Efficacy of Liraglutide in Parkinson's Disease
Not yet reported Cedars-Sinai Medical Center 63 participants Est. completion 2022-08-03 1 siteOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT02960659
Title: Therapeutic Targets in African-American Youth With Type 2 Diabetes
Not yet reported, Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 24 participants Est. completion 2022-05-20 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02963922
Effect and Safety of Liraglutide 3.0 mg in Subjects With Overweight or Obesity and Type 2 Diabetes Mellitus Treated With Basal Insulin
Not yet reported Novo Nordisk A/S 396 participants Est. completion 2018-09-25 54 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT02963935
Effect and Safety of Liraglutide 3.0 mg as an Adjunct to Intensive Behaviour Therapy for Obesity in a Non-specialist Setting
Not yet reported Novo Nordisk A/S 282 participants Est. completion 2018-06-19 10 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT02964247
LIRA-ADD2SGLT2i - Liraglutide Versus Placebo as add-on to SGLT2 Inhibitors.
Not yet reported Novo Nordisk A/S 303 participants Est. completion 2018-05-08 82 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02966275
Post Bariatric Closed Loop Glucagon Trial
Not yet reported Massachusetts General Hospital 10 participants Est. completion 2017-12 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02967757
In-market Utilisation of Liraglutide Used for Weight Management in Europe
Novo Nordisk A/S 316 participants Est. completion 2019-05-28 19 sitesOther conditions: Metabolism and Nutrition Disorder, ObesityView official trial listing → -
Completed NCT NCT02969863
The Monitoring Study
Not yet reported Massachusetts General Hospital 27 participants Est. completion 2017-12-28 1 siteOther conditions: Type1diabetesView official trial listing → -
Completed NCT NCT02971202
Contribution of Hyperinsulinemia vs. Hyperglycemia to Insulin Resistance in Type 1 Diabetes and Maturity Onset Diabetes of the Young, Type 2 (MODY2)
Not yet reported Vanderbilt University 33 participants Est. completion 2019-02 1 siteOther conditions: Type 1 Diabetes Mellitus, Maturity-Onset Diabetes of the Young, Type 2, MODY2, Insulin ResistanceView official trial listing → -
Completed NCT NCT02971228
Feasibility Trial Testing the Bionic Pancreas With ZP4207
Not yet reported Zealand Pharma 13 participants Est. completion 2017-06-07 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02971631
Gastrectomy, Eating Behaviour and GLP-1
Not yet reported Cambridge University Hospitals NHS Foundation Trust 5 participants Est. completion 2018-09-16 1 siteOther conditions: Gastric Cancer, Dumping SyndromeView official trial listing → -
Completed NCT NCT02973321
A Study to Assess the Safety and Efficacy of SAR425899 in Patients With Type 2 Diabetes Mellitus
Not yet reported Sanofi 296 participants Est. completion 2017-12-27 59 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02975297
Exenatide Once Weekly for Smoking Cessation
Not yet reported, Not yet reported The University of Texas Health Science Center, Houston 84 participants Est. completion 2020-01-03 1 siteOther conditions: Smoking CessationView official trial listing → -
Completed NCT NCT02987348
Clinical Outcomes of Exenatide Versus Basal Insulin
AstraZeneca 18000 participants Est. completion 2015-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02994420
Endocrine and Neural Control of Eating in Women
University of Zurich 50 participants Est. completion 2019-12 1 siteOther conditions: Normal Body Weight, ObesityView official trial listing → -
Completed NCT NCT03005951
The Influence of Breakfast on Hormone Responses and Cognitive Performance
Not yet reported Albert Einstein College of Medicine 17 participants Est. completion 2019-01-01 1 siteOther conditions: Insulin ResistanceView official trial listing → -
Completed NCT NCT03010683
Effects of Agonists of Glucagon Like Peptide - 1 Receptors (GLP-1R) on Arterial Stiffness, Endothelial Glycocalyx and Coronary Flow Reserve in Patients With Coronary Artery Disease and Patients With Diabetes Mellitus
Not yet reported University of Athens 60 participants Est. completion 2017-12 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT03011008
Liraglutide as Additional Treatment to Insulin in Patients With Autoimmune Diabetes Mellitus
Not yet reported Second Xiangya Hospital of Central South University 20 participants Est. completion 2021-06 1 siteOther conditions: Type 1 Diabetes Mellitus, Autoimmune DiabetesView official trial listing → -
Status unknown NCT NCT03011021
Safety and Efficacy of Umbilical Cord Blood Regulatory T Cells Plus Liraglutide on Autoimmune Diabetes
Not yet reported, Not yet reported Second Xiangya Hospital of Central South University 40 participants Est. completion 2025-06 1 siteOther conditions: Type1 Diabetes Mellitus, Autoimmune DiabetesView official trial listing → -
Completed NCT NCT03018028
Dose-response, Safety and Efficacy of Oral Semaglutide Versus Placebo and Versus Liraglutide, All as Monotherapy in Japanese Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 243 participants Est. completion 2018-08-15 16 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT03018665
A Study of the Effect of Glucagon-like Peptide 1(GLP-1) Receptor Agonist in Combination With Metformin Therapy on Diabetes Remission in Subjects With Newly Diagnosed Type 2 Diabetes Who Are Overweight or Obese
Not yet reported The First Hospital of Jilin University 200 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03034941
Short Term Weight Loss With Liraglutide and Metformin in Infertile Obese PCOS Patients
Not yet reported University Medical Centre Ljubljana 35 participants Est. completion 2016-12 1 siteOther conditions: Obesity, PCOSView official trial listing → -
Completed NCT NCT03036800
Saxenda in Obesity Services (STRIVE Study)
Not yet reported University of Leicester 392 participants Est. completion 2022-02-25 5 sitesOther conditions: Obesity, Weight Loss, Diabetes MellitusView official trial listing → -
Completed NCT NCT03038620
Impact of Liraglutide 3.0 on Body Fat Distribution
Not yet reported University of Texas Southwestern Medical Center 235 participants Est. completion 2020-10-13 1 siteCardiovascular disease Other conditions: Obesity, Visceral, Fat DisorderView official trial listing → -
Completed NCT NCT03041792
Methodology Study To Examine 6-Week Food Intake With Liraglutide In Obese Subjects
Not yet reported Pfizer 61 participants Est. completion 2018-01-16 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03048578
Clinical Efficacy and Safety of Using 3.0mg Liraglutide to Treat Weight Regain After Roux-en-Y Gastric Bypass Surgery
Not yet reported NYU Langone Health 132 participants Est. completion 2021-03-02 1 siteOther conditions: ObesityView official trial listing → -
Withdrawn NCT NCT03057509
A Pilot Study Of Ga-68-DOTA-TOC Imaging In Participants With Small Bowel Carcinoid Tumors
Not yet reported Massachusetts General Hospital Est. completion 2021-09-30 2 sitesOther conditions: Small Bowel Carcinoid TumorView official trial listing → -
Completed NCT NCT03061227
Characterization of Metabolic and Brain Effects of Rising Glucagon During an Oral Glucose Challenge
Not yet reported University Hospital Tuebingen 32 participants Est. completion 2020-04-30 1 siteMetabolic syndrome Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03068065
Antidiabetic Effects on Intrahepatic Fat
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 87 participants Est. completion 2015-10 1 siteType 2 diabetes Other conditions: Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT03081676
The Effect of GIP and GLP-1 on Insulin and Glucagon Secretion in Patients With HNF1A-diabetes Treated With or Without Sulphonylurea
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2018-06-01 1 siteOther conditions: Maturity-Onset Diabetes of the Young, Type 3View official trial listing → -
Completed NCT NCT03085511
High Quality Protein for Assisting With Weight Loss
Not yet reported Texas Tech University 40 participants Est. completion 2019-05-17 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03091673
Glucose Response of G-Pen (Glucagon Injection) in Pediatric T1D Patients
Not yet reported Xeris Pharmaceuticals 31 participants Est. completion 2017-09-27 7 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03101930
Cardiovascular Effects of GLP-1 Receptor Activation
Not yet reported Vanderbilt University Medical Center 329 participants Est. completion 2021-06-24 1 sitePrediabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT03103009
Treatment Plan for an Individual Patient With Pasireotide for Hyperinsulinemic Hypoglycemia
Not yet reported University of Colorado, Denver 1 participants Est. completion 2017-12-22 1 siteOther conditions: Hyperinsulinemic Hypoglycemia, Post Gastrointestinal Tract Surgery HypoglycaemiaView official trial listing → -
Completed NCT NCT03115099
A Study of LY3325656 in Healthy Participants and Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 80 participants Est. completion 2018-04-05 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03115424
Effect of GLP-1 Receptor Agonism After Sleeve Gastrectomy
Not yet reported Mayo Clinic 46 participants Est. completion 2024-05-30 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03129594
Plasma Glucagon-like Peptide-1 Levels and Acute Myocardial Infarction
Chinese PLA General Hospital 709 participants Est. completion 2015-02Other conditions: Coronary Angiography, Glucagon-like Peptide-1View official trial listing → -
Completed NCT NCT03131687
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 318 participants Est. completion 2018-08-01 49 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT03139305
Effect of Prolonged (72 Hour) Glucagon Administration on Energy Expenditure in Healthy Obese Subjects
Not yet reported AdventHealth Translational Research Institute 30 participants Est. completion 2027-02 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03141632
Effects of Glucagon Like Peptide 1 (GLP-1) Analogues on Fluid Intake
Not yet reported University Hospital, Basel, Switzerland 17 participants Est. completion 2017-05-12 1 siteOther conditions: Thirst, Water-Electrolyte ImbalanceView official trial listing → -
Completed NCT NCT03150030
Hypoglycaemia and Cardiac Arrhythmias in Type 2 Diabetes
University Hospital, Gentofte, Copenhagen 42 participants Est. completion 2020-01-06 1 siteType 2 diabetes Other conditions: Arrhythmia, CardiacView official trial listing → -
Completed NCT NCT03157063
Pilot Data Collection for Activity, Adiposity, and Appetite in Adolescents
Children's Mercy Hospital Kansas City 64 participants Est. completion 2018-11-19 1 siteOther conditions: Physical Activity, Sedentary Lifestyle, Metabolism, Energy BalanceView official trial listing → -
Completed NCT NCT03158805
Saxenda® in Obese or Overweight Patients With Stable Bipolar Disorder (Investigator Initiated)
Not yet reported Lindner Center of HOPE 60 participants Est. completion 2023-01-01 1 siteOther conditions: Bipolar Disorder, ObesityView official trial listing → -
Completed NCT NCT03172494
A Trial Comparing Insulin Degludec/Liraglutide, Insulin Degludec, and Liraglutide in Chinese Subjects With Type 2 Diabetes Inadequately Controlled on Oral Antidiabetic Drugs (OADs)
Not yet reported Novo Nordisk A/S 720 participants Est. completion 2019-07-13 36 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03176524
A Trial to Investigate the Safety and the Pharmacokinetic, Pharmacodynamic Characteristics of Two BioChaperone® Glucagon Formulations Compared to Marketed GlucaGen® in Subjects With T1DM
Not yet reported Adocia 27 participants Est. completion 2017-09-04 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03181191
The Anatomical Location, Cellular Origin and Molecular Basis of Gut-derived Glucagon Secretion
Not yet reported University Hospital, Gentofte, Copenhagen 24 participants Est. completion 2017-12-03 1 siteOther conditions: Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT03182426
Stem Cell Mobilization (Plerixafor) and Immunologic Reset in Type 1 Diabetes (T1DM)
Not yet reported, Not yet reported University of Alberta 22 participants Est. completion 2024-07-15 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03191396
Research Study Comparing a New Medicine Semaglutide to Liraglutide in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 577 participants Est. completion 2018-08-13 92 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03195257
Glucose-Dependent Insulinotropic Polypeptide - Effects on Markers of Bone Turnover in Patients With Type 1 Diabetes
Not yet reported Mikkel Christensen 10 participants Est. completion 2016-12-01Other conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03204396
Smoking Cessation Facilitated by Glucagon-like Peptide-1 (GLP-1) Analogues
Not yet reported University Hospital, Basel, Switzerland 256 participants Est. completion 2022-08-30 1 siteOther conditions: Glucagon-like Peptide-1, Smoking Cessation, Weight Change, Body, CravingView official trial listing → -
Completed NCT NCT03216226
A Trial to Evaluate the Immunogenicity of Dasiglucagon and GlucaGen in Patients With Type 1 Diabetes Mellitus
Not yet reported Zealand Pharma 112 participants Est. completion 2018-02-13 7 sites Stand-aloneOther conditions: Hypoglycemia, Diabetes Mellitus, Type 1View official trial listing → -
Terminated NCT NCT03217175
Efficacy of Glucagon In the Prevention of Hypoglycemia During Mild Exercise
Not yet reported Massachusetts General Hospital 22 participants Est. completion 2018-03-09 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03232112
Does Treatment With GLP-1 Reduce Alcohol Intake in Patients With Alcohol Dependence?
Not yet reported Anders Fink-Jensen, MD, DMSci 152 participants Est. completion 2020-10-05 1 siteAlcohol use disorder Other conditions: Addiction, AlcoholView official trial listing → -
Completed NCT NCT03235050
A Study to Evaluate the Efficacy and Safety of MEDI0382 in the Treatment of Overweight and Obese Subjects With Type 2 Diabetes
Not yet reported AstraZeneca 834 participants Est. completion 2019-06-14 119 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03241303
Delineation of the Role of Glucagon-like Peptide-1 Signalling in Relation to Increased Carbohydrate Content in the Distal Small Intestines
Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2018-01-01 1 siteOther conditions: Glucose Metabolism DisordersView official trial listing → -
Active, not recruiting NCT NCT03241706
Liver Glycogen and Hypoglycemia in Humans
Not yet reported Jason Winnick 40 participants Est. completion 2028-05-31 1 siteOther conditions: Hypoglycemia; IatrogenicView official trial listing → -
Completed NCT NCT03246451
The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D
Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2017-12-10 1 siteOther conditions: Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT03246828
Glucagon in MODY (Maturity Onset Diabetes of the Young)
Not yet reported University of Oxford 10 participants Est. completion 2022-08-01 1 siteOther conditions: MODY1, MODY3View official trial listing → -
Completed NCT NCT03249506
Cardiovascular Outcomes in Participants With Type 2 Diabetes Mellitus (T2DM)
Janssen Research & Development, LLC 25358 participants Est. completion 2017-11-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03255629
Closed-Loop Glucagon Pump for Treatment of Post-Bariatric Hypoglycemia
Not yet reported, Not yet reported Joslin Diabetes Center 18 participants Est. completion 2018-08-22 1 siteOther conditions: Post-bariatric HypoglycemiaView official trial listing → -
Completed NCT NCT03258853
Feasibility of Outpatient Closed Loop Control With the iLet Bionic Pancreas in Cystic Fibrosis Related Diabetes
Not yet reported Massachusetts General Hospital 22 participants Est. completion 2022-06-29 1 siteOther conditions: Cystic Fibrosis-related DiabetesView official trial listing → -
Completed NCT NCT03260881
Liraglutide Effects on Epicardial Fat Inflammatory Genes
Not yet reported University of Miami 38 participants Est. completion 2024-09-05 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Terminated NCT NCT03279731
Binge Eating Liraglutide Intervention
Not yet reported Kelly Allison 36 participants Est. completion 2019-10-01 1 siteOther conditions: Binge-Eating DisorderView official trial listing → -
Completed NCT NCT03292185
A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide Compared With Insulin Degludec and Liraglutide in Healthy Chinese Subjects
Not yet reported Novo Nordisk A/S 24 participants Est. completion 2018-01-02 1 siteType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03292315
Once Weekly GLP-1 in Persons With Spinal Cord Injury
Not yet reported James J. Peters Veterans Affairs Medical Center 5 participants Est. completion 2023-03-01 1 siteOther conditions: Spinal Cord Injuries, Insulin Resistance, Pre Diabetes, ObesityView official trial listing → -
Completed NCT NCT03311724
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 111 participants Est. completion 2018-04-24 13 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03314844
Plasma Glucagon-like Peptide-1 Levels and In-hospital Complications in ST-segment Elevation Myocardial Infarction
Chinese PLA General Hospital 564 participants Est. completion 2015-02-01Cardiovascular disease Other conditions: Glucagon-like Peptide-1, Bleeding, ComplicationsView official trial listing → -
Completed NCT NCT03322631
A Study of Tirzepatide (LY3298176) in Japanese Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 48 participants Est. completion 2018-11-28 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03331289
Can Exenatide Prevent Increase in EGP in Response to Dapagliflozin-induced Increase in Glucosuria
Not yet reported The University of Texas Health Science Center at San Antonio 107 participants Est. completion 2022-11-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03339453
A Study of Nasal Glucagon in Participants With Type 1 Diabetes Mellitus
Not yet reported Eli Lilly and Company 70 participants Est. completion 2018-01-13 2 sitesOther conditions: Hypoglycemia, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03341429
Evaluation of Liraglutide 3.0mg in Patients With Poor Weight-loss and a Suboptimal Glucagon-like Peptide-1 Response
Not yet reported University College, London 70 participants Est. completion 2020-06-11 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03347890
Reward Mechanisms in Obesity
Not yet reported Zoltan Pataky 70 participants Est. completion 2020-03-30 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03350191
A Clinical Study to Investigate if SAR425899 Binds to the Liver and Pancreas in Overweight to Obese Type 2 Diabetes Mellitus Patients
Not yet reported Sanofi 13 participants Est. completion 2018-06-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03353948
The Effect of a Liraglutide on IVF in Obese PCOS
Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2016-09-01Other conditions: Polycystic Ovary Syndrome, Obesity, Infertility, FemaleView official trial listing → -
Completed NCT NCT03363464
Comparative Effectiveness of Empagliflozin in the US
Boehringer Ingelheim 230000 participants Est. completion 2026-07-09 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT03371862
Liraglutide on Decreasing Parenteral Support in Short Bowel Patients (SLIPS)
Not yet reported Imperial College London Est. completion 2020-09-30 1 siteOther conditions: Short Bowel SyndromeView official trial listing → -
Completed NCT NCT03374956
Individualized Obesity Pharmacotherapy
Not yet reported Mayo Clinic 193 participants Est. completion 2022-05-26 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03375463
A Study of Tirzepatide (LY3298176) in Healthy Participants
Not yet reported Eli Lilly and Company 52 participants Est. completion 2018-12-27 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT03378635
A Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Type 1 Diabetes Subjects
Not yet reported Zealand Pharma 170 participants Est. completion 2018-05-25 5 sitesOther conditions: Hypoglycemia, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03414333
To Determine the Effect of GLP1 on Cognitive Function, Brain Glucose Metabolism and Neuroplasticity.
Not yet reported University of Pisa 14 participants Est. completion 2018-06 1 siteOther conditions: Glucose Metabolism Disorders, Obesity, Degenerative Brain DisorderView official trial listing → -
Status unknown NCT NCT03421119
Comparing Efficacy and Safety of CinnaGen-liraglutide Versus Victoza® in Patients With Type II Diabetes
Not yet reported Cinnagen 300 participants Est. completion 2019-12-01Type 2 diabetesView official trial listing → -
Completed NCT NCT03421379
A Study of Nasal Glucagon (LY900018) in Japanese Participants With Diabetes Mellitus
Not yet reported Eli Lilly and Company 75 participants Est. completion 2018-08-20 4 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT03422666
Plasma Lipoprotein Response to Glucagon-like Peptide-2
Not yet reported, Not yet reported University Health Network, Toronto 10 participants Est. completion 2021-12-01 1 siteOther conditions: HyperlipidemiasView official trial listing → -
Completed NCT NCT03422848
Hydration to Optimize Metabolism
Not yet reported Region Skane 797 participants Est. completion 2025-11-03 1 siteOther conditions: Glucose, High BloodView official trial listing → -
Completed NCT NCT03424044
Three Way Crossover Closed Loop Study With Xeris Glucagon
Not yet reported Oregon Health and Science University 23 participants Est. completion 2019-05-17 1 siteOther conditions: Type1diabetesView official trial listing → -
Status unknown NCT NCT03426085
The Effects of Liraglutide on Sudomotor Function and Inflammation in Type 2 Diabetes
Not yet reported Eastern Virginia Medical School 44 participants Est. completion 2020-08 1 siteOther conditions: Autonomic Nervous System Diseases, Sweat Gland Diseases, Diabetic Neuropathy With Neurologic ComplicationView official trial listing → -
Status unknown NCT NCT03426956
Glucose Absorption and Gut Hormone Secretion After Gastric Bypass
Not yet reported Hvidovre University Hospital 10 participants Est. completion 2019-05-01 1 siteOther conditions: OverweightView official trial listing → -
Completed NCT NCT03439072
G-Pen™ Compared to Lilly Glucagon for Hypoglycemia Rescue in Adults With Type 1 Diabetes
Not yet reported Xeris Pharmaceuticals 81 participants Est. completion 2018-05-03 6 sitesOther conditions: Insulin Hypoglycemia, Type 1 Diabetes Mellitus, Severe HypoglycemiaView official trial listing → -
Completed NCT NCT03442972
Glucagon-like Peptide-2 Mediated Secretion of Stored Enteral Lipids
Not yet reported, Not yet reported University Health Network, Toronto 21 participants Est. completion 2021-12-01 2 sitesOther conditions: HyperlipidemiasView official trial listing → -
Status unknown NCT NCT03444142
Effect of Exenatide LAR or Dulaglutide on the Variability of 24-hour Heart Rate and Blood Pressure in Type 2 Diabetes
Not yet reported University of Guadalajara 30 participants Est. completion 2021-11-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03444467
First Research Study to Compare a Possible New Medicine NNC9204-1513 to the Medicine Glucagon, in Healthy People.
Not yet reported Novo Nordisk A/S 36 participants Est. completion 2018-05-24 1 siteType 2 diabetes Other conditions: Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03449654
Effect of Liraglutide on Vascular Inflammation in Type-2 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 102 participants Est. completion 2019-08-16 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03456687
Effects of Exenatide on Motor Function and the Brain
Not yet reported University of Florida 5 participants Est. completion 2021-08-25 1 siteOther conditions: Parkinson's DiseaseView official trial listing → -
Completed NCT NCT03466021
Effects of Liraglutide in Chronic Obstructive Pulmonary Disease
Not yet reported Claus Bogh Juhl 40 participants Est. completion 2020-05-31 2 sitesOther conditions: Pulmonary Disease, Chronic ObstructiveView official trial listing → -
Completed NCT NCT03479762
In Market Utilisation of Liraglutide Used for Weight Management in the UK: a Study in the CPRD Primary Care Database
Novo Nordisk A/S 105 participants Est. completion 2022-09-12 1 siteOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT03480022
Liraglutide 3mg (Saxenda) on Weight, Body Composition, Hormonal and Metabolic Parameters in Obese Women With PCOS
Not yet reported Woman's 88 participants Est. completion 2021-05-19 1 siteOther conditions: Pre Diabetes, Polycystic Ovary Syndrome, Obesity AndroidView official trial listing → -
Completed NCT NCT03482024
A Study of Tirzepatide (LY3298176) in Participants With Impaired Kidney Function
Not yet reported Eli Lilly and Company 45 participants Est. completion 2019-08-19 4 sitesOther conditions: Renal Insufficiency, End Stage Renal DiseaseView official trial listing → -
Completed NCT NCT03486392
A Study to Evaluate the Safety and Efficacy of JNJ-64565111 in Non-diabetic Severely Obese Participants
Not yet reported Janssen Research & Development, LLC 474 participants Est. completion 2019-03-08 51 sitesOther conditions: ObesityView official trial listing → -
Terminated NCT NCT03490942
Glucagon Infusion in T1D Patients With Recurrent Severe Hypoglycemia: Effects on Counter-Regulatory Responses
Not yet reported Xeris Pharmaceuticals 49 participants Est. completion 2020-02-10 5 sitesOther conditions: Hypoglycemia Unawareness, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03492580
A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease
Janssen Research & Development, LLC 714582 participants Est. completion 2018-06-25 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT03498001
Effects of GLP-1 Agonists on CArdiac Steatosis Evaluated by Magnetic Resonance Imaging
Not yet reported Centre Hospitalier Universitaire Dijon 42 participants Est. completion 2023-12-20 1 siteOther conditions: Type II DiabetesView official trial listing → -
Terminated NCT NCT03500484
Effect of Liraglutide on Neural Responses to High Fructose Corn Syrup in Individuals With Obesity.
Not yet reported Yale University 13 participants Est. completion 2020-06-25 1 siteOther conditions: Obesity, Childhood, Neural DevelopmentView official trial listing → -
Completed NCT NCT03502083
Human Vasodilatory Effect of GLP-1
Not yet reported Papworth Hospital NHS Foundation Trust 11 participants Est. completion 2017-03-01Type 2 diabetes Other conditions: Coronary Stenosis, Angina, StableView official trial listing → -
Completed NCT NCT03507621
Sevoflurane Versus Propofol; Neuro Endocrine Response in Patients of Oociyt Pick up
Yavuz Orak 60 participants Est. completion 2019-04-30 1 siteOther conditions: Anesthesia, Infertility, Pain, Postoperative, Stress, PsychologicalView official trial listing → -
Withdrawn NCT NCT03508739
Glucagon-like Peptide-1 Metabolism and Acute Neprilysin Inhibition
Not yet reported University of Pennsylvania Est. completion 2026-06-30 1 siteType 2 diabetes Other conditions: Pre-diabetic, Hypertension, Elevated Blood PressureView official trial listing → -
Completed NCT NCT03520062
The Effect of Liraglutide on Pancreatic Hormones and Its Size
Not yet reported Nicolai Jacob Wewer Albrechtsen 14 participants Est. completion 2020-01-01 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03523273
Pilot Study of the Effect of Liraglutide 3.0 mg on Weight Loss and Gastric Functions in Obesity
Not yet reported Michael Camilleri, MD 136 participants Est. completion 2021-08-31 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03526445
Hepatic Metabolic Changes in Response to Glucagon Infusion
Not yet reported Steno Diabetes Center Copenhagen 27 participants Est. completion 2019-06-12 1 siteOther conditions: Non-Alcoholic Fatty Liver Disease, Total Pancreatectomy, Diabetes MellitusView official trial listing → -
Completed NCT NCT03528174
Single Hormone Closed Loop Study With PDT Sensor
Not yet reported Oregon Health and Science University 10 participants Est. completion 2018-07-01 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03533179
Glucagon's Cardiovascular Effects With and Without Beta-blocker-induced Cardioinhibition
Not yet reported University Hospital Bispebjerg and Frederiksberg 10 participants Est. completion 2019-10-01 1 siteOther conditions: Drug Overdose, Overdose of Beta-adrenergic Blocking DrugView official trial listing → -
Completed NCT NCT03534310
Weight Loss With Intensive Lifestyle Modifications Plus Bariatric Surgery Versus Liraglutide 3 mg
Not yet reported Catholic University of the Sacred Heart 75 participants Est. completion 2017-04-10 1 siteOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT03543423
Studies of the Early Meal Phase in Healthy Individuals - Nutrient Absorption and Gastrointestinal Hormone Secretion
Not yet reported University of Copenhagen 12 participants Est. completion 2019-06-30 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT03547427
Glucagon Counterregulation in Type 1 Diabetes
Not yet reported University of Virginia 13 participants Est. completion 2019-03-11 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03555994
A Study to Investigate the Effect of MEDI0382 on Hepatic Glycogen Metabolism in Overweight and Obese Subjects With Type 2 Diabetes Mellitus.
Not yet reported MedImmune LLC 51 participants Est. completion 2021-04-14 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03556098
Glucose-dependent Insulinotropic Polypeptide as a Safeguard Against Hypoglycemia in Patients With Type 1 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 12 participants Est. completion 2020-02-11 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03560336
A Regulatory Post-marketing Surveillance (rPMS) Study to Evaluate the Safety and Effectiveness of Saxenda®(Liraglutide 3.0 mg) in Obese Patients and Overweight Patients With Obesity-related Comorbidities in Routine Clinical Practice in Korea.
Novo Nordisk A/S 758 participants Est. completion 2020-12-02 28 sitesOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT03573934
Gut Hormones and Bone Remodeling in Humans (KS-2)
Not yet reported University of Copenhagen 10 participants Est. completion 2018-03-15 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT03574064
Effects of Gut Peptides on Bone Remodeling
Not yet reported University of Copenhagen 10 participants Est. completion 2019-01-01 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT03619330
Testosterone Replacement Therapy and Liraglutide Effects on Weight Loss in Hypogonadism.
Not yet reported University Medical Centre Ljubljana 30 participants Est. completion 2015-08 1 siteOther conditions: Hypogonadism, ObesityView official trial listing → -
Completed NCT NCT03632759
Targeting Beta Cell Dysfunction With Liraglutide or Golimumab in Longstanding T1D
Not yet reported Carla Greenbaum, MD 16 participants Est. completion 2021-11-09 2 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT03650582
Intranasal Glucagon and Energy Balance
Not yet reported, Not yet reported University Health Network, Toronto 20 participants Est. completion 2018-10-30 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03659461
Glucagon-like Peptide-1 Levels, Insulin Resistance and Insulin Sensitivity Index in Type 2 Diabetes Mellitus
Not yet reported National University of Malaysia 174 participants Est. completion 2020-01-31 1 siteType 2 diabetesPrediabetesView official trial listing → -
Completed NCT NCT03667053
Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in T1DM Children
Not yet reported Zealand Pharma 42 participants Est. completion 2019-06-28 5 sitesOther conditions: HypoglycemiaView official trial listing → -
Status unknown NCT NCT03671733
Effects of GLP-1 RAs on Weight and Metabolic Indicators in Obese Patients
Not yet reported Xiangya Hospital of Central South University 150 participants Est. completion 2022-09-01 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03672812
The Use of Liraglutide in Brain Death
Not yet reported Hospital de Clinicas de Porto Alegre 50 participants Est. completion 2022-02-10 1 siteOther conditions: Brain DeathView official trial listing → -
Completed NCT NCT03680482
To Compare the Effects of Non-nutritive Sweeteners Intake in Subjects With T2DM
Not yet reported University of Chile 17 participants Est. completion 2017-08-31Type 2 diabetesView official trial listing → -
Completed NCT NCT03682172
Effect of Glucagon-like Peptide 2 on Gallbladder Motility After a Meal in Young, Healthy Male Subjects
Not yet reported Steno Diabetes Center Copenhagen 15 participants Est. completion 2020-07-01 1 siteOther conditions: Effect of Glucagon-like Peptide 2 on Gallbladder MotilityView official trial listing → -
Completed NCT NCT03688711
Trial to Confirm the Clinical Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Subjects With T1DM
Not yet reported Zealand Pharma 45 participants Est. completion 2019-03-11 3 sitesOther conditions: Hypoglycemia, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03690206
Efficacy And Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome (SBS)
Not yet reported Zealand Pharma 106 participants Est. completion 2022-07-26 29 sitesOther conditions: Short Bowel SyndromeView official trial listing → -
Completed NCT NCT03702660
Effect of GIP After a Meal in Patients With Type 2 Diabetes
Not yet reported University Hospital, Gentofte, Copenhagen 10 participants Est. completion 2018-01-23 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03707171
Effects of Liraglutide on the Cognitive Function in Patients With Type 2 Diabetes Mellitus
Not yet reported Third Military Medical University 30 participants Est. completion 2019-05-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03712098
Daily Liraglutide for Nicotine Dependence
Not yet reported Rebecca Ashare 40 participants Est. completion 2022-05-25 1 siteOther conditions: Smoking Cessation, Weight, BodyView official trial listing → -
Completed NCT NCT03713190
Effects of Empagliflozin on Endogenous Glucose Production in End Stage Renal Disease(ESRD).
Not yet reported University of Pisa 25 participants Est. completion 2020-03-15 1 siteOther conditions: End Stage Renal DiseaseView official trial listing → -
Completed NCT NCT03714594
Effects of Dapagliflozin+Saxagliptin in Addition to Metformin v/s Saxagliptin or Dapagliflozin in Patients With DM2.
Not yet reported University of Pisa 48 participants Est. completion 2022-08-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03717688
The Effects of Neprilysin on Glucagon-like Peptide-1
Not yet reported Nicolai Jacob Wewer Albrechtsen 19 participants Est. completion 2019-05-14 1 siteHeart failure Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03728959
Effects of a Liquid Meal and Gut Hormones (GIP and GLP-2) on Bone Remodeling in Participants With Hypoparathyroidism.
Not yet reported University of Copenhagen 7 participants Est. completion 2019-04-12 1 siteOther conditions: HypoparathyroidismView official trial listing → -
Completed NCT NCT03730662
A Study of Tirzepatide (LY3298176) Once a Week Versus Insulin Glargine Once a Day in Participants With Type 2 Diabetes and Increased Cardiovascular Risk
Not yet reported Eli Lilly and Company 2002 participants Est. completion 2021-04-22 216 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03734718
The Role of Glucose-Dependent Insulinotropic Polypeptide in the Pathological Glucose Homeostasis Of Type 1 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 20 participants Est. completion 2019-12-31 1 siteOther conditions: Diabetes Mellitus, Type 1, HypoglycemiaView official trial listing → -
Completed NCT NCT03737240
IDegLira HIGH Trial
Not yet reported Emory University 145 participants Est. completion 2022-07-08 2 sitesOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT03738865
G-Pen Compared to Glucagen Hypokit for Severe Hypoglycemia Rescue in Adults With Type 1 Diabetes
Not yet reported Xeris Pharmaceuticals 132 participants Est. completion 2019-04-02 7 sitesOther conditions: Insulin Hypoglycemia, Type 1 Diabetes Mellitus, Severe HypoglycemiaView official trial listing → -
Completed NCT NCT03757130
Multiple Ascending Dose Study of AMG 598 in Adults With Obesity
Not yet reported Amgen 50 participants Est. completion 2019-12-16 4 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT03765502
A Study Comparing User Experience of Different Delivery Devices for Glucagon
Not yet reported Eli Lilly and Company 99 participants Est. completion 2019-01-03 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT03768518
GLP-1 Receptor Expression in CHI
Radboud University Medical Center 40 participants Est. completion 2019-02-01 1 siteOther conditions: Congenital HyperinsulinismView official trial listing → -
Completed NCT NCT03770637
Glucagon Ready to Use (RTU) in Subjects With Hyperinsulinemic Hypoglycemia After Bariatric Surgery
Not yet reported Xeris Pharmaceuticals 14 participants Est. completion 2020-02-26 5 sitesOther conditions: Hyperinsulinemic HypoglycemiaView official trial listing → -
Completed NCT NCT03777176
A Two-Period Open-label Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism
Not yet reported Zealand Pharma 32 participants Est. completion 2020-10-05 10 sitesOther conditions: Congenital HyperinsulinismView official trial listing → -
Completed NCT NCT03795701
To Predict Weight Loss Response to Liraglutide (Saxenda®), From fMRI-based Determination of Food Cue Reactivity
Not yet reported Texas Tech University 73 participants Est. completion 2022-05-01 2 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT03800732
The Influence of Nocturnal Food Intake in Eating Behavior of Night Workers
Not yet reported Federal University of Uberlandia 10 participants Est. completion 2020-07-01 1 siteOther conditions: Shift Work Type Circadian Rhythm Sleep DisorderView official trial listing → -
Completed NCT NCT03807440
DIA_CENTRAL:T2D Treatment Pattern in Central Europe
Boehringer Ingelheim 4083 participants Est. completion 2021-08-31 177 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03819790
The Effect of Soliqua on Glucose Variability in Type 2 Patients Among South Asians
Not yet reported LMC Diabetes & Endocrinology Ltd. 119 participants Est. completion 2019-11-19 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03819972
The Dose Response of Calcium Co-ingested With Protein on GLP-1 Concentrations
Not yet reported University of Bath 18 participants Est. completion 2021-03-31 1 siteOther conditions: GLP-1 ConcentrationView official trial listing → -
Completed NCT NCT03823339
A Research Study, Looking at How Xultophy® Works in People With Type 2 Diabetes in Local Clinical Practice in United Arab Emirates
Novo Nordisk A/S 300 participants Est. completion 2020-12-14 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03826381
NAFLD Among Patients With Type 2 Diabetes and CKD
Copenhagen University Hospital, Rigshospitalet 100 participants Est. completion 2021-06-23 1 siteChronic kidney diseaseType 2 diabetes Other conditions: Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT03829800
Formulas for Diabetes With Sucromalt & Isomaltulose on Glycemic Index, Hormones & Subjective Appetite in Type 2 Diabetes
Not yet reported Universidad del Zulia 23 participants Est. completion 2018-11-15Type 2 diabetesView official trial listing → -
Completed NCT NCT03829891
Study for Beinaglutide Versus Glargine Therapy in Glycemic Variability of Type 2 Diabetes Mellitus
Not yet reported Xijing Hospital 60 participants Est. completion 2020-12-04 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03835013
Haemodynamic Effects of GLP-1 and Glucagon in Healthy Male Volunteers
Not yet reported Cambridge University Hospitals NHS Foundation Trust 26 participants Est. completion 2021-11-01 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT03840278
The Bihormonal iLet Bionic Pancreas Feasibility Study
Not yet reported, Not yet reported Massachusetts General Hospital 12 participants Est. completion 2019-07-03 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03841526
Glucagon Ready-to-Use (RTU) for Prevention of Exercise-Induced Hypoglycemia During Aerobic Exercise in Adults With T1D
Not yet reported Xeris Pharmaceuticals 48 participants Est. completion 2020-04-02 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT03849235
A Pathophysiological Study of the Postprandial Human Liver (PLS)
Not yet reported Copenhagen University Hospital, Hvidovre 87 participants Est. completion 2025-09-01 1 siteOther conditions: Cirrhosis, Fatty LiverView official trial listing → -
Completed NCT NCT03856047
Research Study Investigating How Well NNC0174-0833 Works in People Suffering From Overweight or Obesity.
Not yet reported Novo Nordisk A/S 706 participants Est. completion 2021-03-25 54 sitesOther conditions: Overweight, ObesityView official trial listing → -
Active, not recruiting NCT NCT03856632
Liraglutide Effect in Atrial Fibrillation
Not yet reported University of Miami 60 participants Est. completion 2026-12-31 1 siteOther conditions: Atrial FibrillationView official trial listing → -
Completed NCT NCT03859323
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Ascending, Subcutaneous, Single and Multiple Doses of SHP681 (Glucagon-like Peptide-2 [GLP-2] Analog-Fc Fusion) in Healthy Adult Participants
Not yet reported Shire 104 participants Est. completion 2020-01-06 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT03860688
Effects of Oral Glucose and Teduglutide on Plasma Lipoproteins
Not yet reported, Not yet reported University Health Network, Toronto 15 participants Est. completion 2022-05 1 siteOther conditions: HyperlipidemiasView official trial listing → -
Completed NCT NCT03861039
A Long-term Safety Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 443 participants Est. completion 2021-02-16 34 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03861052
A Study of Tirzepatide (LY3298176) Compared to Dulaglutide in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 636 participants Est. completion 2021-03-31 46 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT03866421
NAFLD Among Patients With Chronic Kidney Disease and the Effect of Kidney Transplantation
Copenhagen University Hospital, Rigshospitalet 3 participants Est. completion 2022-03-31 1 siteChronic kidney diseasePrediabetes Other conditions: Non-Alcoholic Fatty Liver Disease, Kidney TransplantView official trial listing → -
Completed NCT NCT03867656
Effects of Gut Peptides on Bone Remodeling. KS-4-Diabetes-19
Not yet reported University of Copenhagen 10 participants Est. completion 2020-06-26 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03882970
A Study of Tirzepatide (LY3298176) Versus Insulin Degludec in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 1444 participants Est. completion 2021-01-04 122 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03885297
3mg Liraglutide for Overweight or Obesity
University Hospitals Coventry and Warwickshire NHS Trust 43 participants Est. completion 2020-12-18 1 siteOther conditions: Overweight, Obesity, Infertility, FemaleView official trial listing → -
Completed NCT NCT03888157
A Research Study Looking at How Victoza® Works in People With Type 2 Diabetes in Iran, Followed in Local Clinical Routine
Novo Nordisk A/S 839 participants Est. completion 2020-10-21 16 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03893526
Effect of Neprilysin on Glucagon-Like Peptide-1 in Patients With Type 2 Diabetes
Not yet reported University of Copenhagen 12 participants Est. completion 2021-03-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03895697
A Trial to Compare the Efficacy and Safety of 2 Different Batches of Subcutaneous Dasiglucagon in Patients With T1DM
Not yet reported Zealand Pharma 92 participants Est. completion 2019-07-30 1 siteOther conditions: Hypoglycemia, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT03905707
Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS
Not yet reported Zealand Pharma 150 participants Est. completion 2026-04-30 27 sitesOther conditions: Short Bowel SyndromeView official trial listing → -
Completed NCT NCT03919617
Metabolic Pathways of GRA in Patients With Type 1 Diabetes
Not yet reported, Not yet reported University of California, San Diego 4 participants Est. completion 2022-05-31 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03936049
Replication of the LEADER Diabetes Trial in Healthcare Claims
Brigham and Women's Hospital 168690 participants Est. completion 2021-02-18 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT03940742
A Study of Tirzepatide in Participants With Impaired Liver Function
Not yet reported Eli Lilly and Company 32 participants Est. completion 2020-09-22 3 sitesOther conditions: Hepatic InsufficiencyView official trial listing → -
Completed NCT NCT03941236
Extension Trial Evaluating the Long-term Safety and Efficacy of Dasiglucagon in Children With Congenital Hyperinsulinism
Not yet reported Zealand Pharma 42 participants Est. completion 2026-05-26 10 sitesOther conditions: Congenital HyperinsulinismView official trial listing → -
Status unknown NCT NCT03948347
Liraglutide in Acute Minor Ischemic Stroke or High-risk Transient Ischemic Attack Patients With Type 2 Diabetes Mellitus
Not yet reported First Affiliated Hospital of Jinan University 1708 participants Est. completion 2024-06 1 siteCardiovascular diseaseType 2 diabetes Other conditions: Transient Ischemic AttackView official trial listing → -
Completed NCT NCT03950245
Incretin Hormone Antagonism After Bariatric Surgery
Not yet reported Hvidovre University Hospital 36 participants Est. completion 2021-04-16 2 sitesOther conditions: Bariatric SurgeryView official trial listing → -
Completed NCT NCT03951753
A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus (T2DM)
Not yet reported Eli Lilly and Company 117 participants Est. completion 2021-04-08 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03954834
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Not Controlled With Diet and Exercise Alone
Not yet reported Eli Lilly and Company 478 participants Est. completion 2020-10-28 53 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03954873
Glucagon-like Peptide 2 - a Glucose Dependent Glucagonotropic Hormone?
Not yet reported University Hospital, Gentofte, Copenhagen 10 participants Est. completion 2020-06-01 1 siteOther conditions: Glucose Metabolism Disorders, Endocrine or Metabolic DiseaseView official trial listing → -
Completed NCT NCT03955575
Treatment of Bile Acid Malabsorption With Liraglutide
Not yet reported Filip Krag Knop 52 participants Est. completion 2022-05-31 1 siteOther conditions: Bile Acid MalabsorptionView official trial listing → -
Status unknown NCT NCT03965000
Human Solute Carrier Family 5 Member 2 (SLC5A2) Deficiency and the Glucagon-Incretin Axis
Medical University Innsbruck 10 participants Est. completion 2022-01 1 siteCardiovascular disease Other conditions: Familial Renal Glucosuria, Diabetes MellitusView official trial listing → -
Completed NCT NCT03965130
The Effect of Glucagon on Rates of Hepatic Mitochondrial Oxidation in Man Assessed by PINTA
Not yet reported Yale University 10 participants Est. completion 2023-07-06 1 siteOther conditions: Healthy ParticipantsView official trial listing → -
Completed NCT NCT03970044
Effectiveness of Exenatide Plus Dapagliflozin on 24 Hour Glucose Variability Measured by CGM. A Proof of Concept.
Not yet reported Consano Clinical Research, LLC 67 participants Est. completion 2021-06-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03970772
Mini-Dose Glucagon to Treat Fasting-induced Hypoglycemia During Ramadan
Not yet reported Qassim University 20 participants Est. completion 2019-08-15 1 siteOther conditions: Fasting Hypoglycemia, Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT03986008
Effects of Benaglutide on Weight and Gut Microbiota in Obese Patients
Not yet reported Xiangya Hospital of Central South University 60 participants Est. completion 2021-12-23 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT03987919
A Study of Tirzepatide (LY3298176) Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 1879 participants Est. completion 2021-02-15 127 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03993132
A Study Using Medical Records of Danish People With Type 2 Diabetes Comparing Empagliflozin and Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) in the Occurrence of Serious Cardiovascular Outcomes
Boehringer Ingelheim 26774 participants Est. completion 2022-06-16 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04004988
A Study of Tirzepatide Administered by Two Different Devices in Healthy Participants
Not yet reported Eli Lilly and Company 47 participants Est. completion 2019-12-16 1 siteOther conditions: HealthyView official trial listing → -
Active, not recruiting NCT NCT04007809
Phenotypic and Genotypic Characterization of New-onset Type I Diabetes
Not yet reported Université Catholique de Louvain 98 participants Est. completion 2027-06-30 1 siteOther conditions: Type1diabetesView official trial listing → -
Status unknown NCT NCT04008290
The Effect of Liraglutide on the GIT
Not yet reported Universitaire Ziekenhuizen KU Leuven 15 participants Est. completion 2021-04-01Other conditions: ObesityView official trial listing → -
Completed NCT NCT04009603
Comparison of Probiotics, Metformin & Their Combination Therapy in the Treatment of PCOS
Not yet reported Ziauddin University 78 participants Est. completion 2020-01-28 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04020445
Simplification of Complex Insulin Regimens With Preserving Good Glycemic Control in Type 2 Diabetes
Bekes County Central Hospital 150 participants Est. completion 2022-01-01 1 siteOther conditions: HBA1c, Body Weight, HypoglycemiaView official trial listing → -
Status unknown NCT NCT04029272
Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients
Not yet reported Peking Union Medical College Hospital 80 participants Est. completion 2020-12-31 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT04034524
Cardiovascular Outcomes and HbA1c Among Patients With Type 2 Diabetes Newly Initiating GLP1RAs vs Basal Insulin
Brigham and Women's Hospital 20000 participants Est. completion 2020-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04039503
A Study of Tirzepatide (LY3298176) Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine With or Without Metformin
Not yet reported Eli Lilly and Company 475 participants Est. completion 2021-01-13 48 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04042142
Glucagon Resistance in Patients With NAFLD
Not yet reported University of Aarhus 28 participants Est. completion 2022-08-18 1 siteOther conditions: Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis, Glucose Metabolism DisordersView official trial listing → -
Status unknown NCT NCT04046822
Effect of Liraglutide on Microbiome in Obesity
Not yet reported Federico II University 70 participants Est. completion 2020-04-30 1 siteOther conditions: Obesity, Weight Loss, MicrobiomeView official trial listing → -
Completed NCT NCT04050553
A Study of Tirzepatide in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 42 participants Est. completion 2022-01-25 1 siteType 2 diabetes Other conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT04050670
A Study of Tirzepatide at Different Injection Sites in Participants With Different Body Sizes
Not yet reported Eli Lilly and Company 54 participants Est. completion 2020-04-03 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT04053712
Dual-hormone Closed-loop Glucose Control in Type 1 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 13 participants Est. completion 2021-03-19 1 siteOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Withdrawn NCT NCT04057261
Effect of Liraglutide on the Metabolic Profile in Patients With Type 2 Diabetes and Cardiovascular Disease
Not yet reported RWTH Aachen University Est. completion 2022-11 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT04061473
Involvement of Dipeptidyl Peptidase-4 and Sodium-glucose Co-transporter-2 in Extrapancreatic Glucagon Secretion
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2019-08-20 1 siteOther conditions: Diabetes After Total PancreatectomyView official trial listing → -
Completed NCT NCT04064203
The Effect of Insulin-induced Hypoglycaemia on Gut-derived Glucagon Secretion (Px-Hypo)
Not yet reported University Hospital, Gentofte, Copenhagen 24 participants Est. completion 2018-09-20 1 siteOther conditions: Diabetes After Total PancreatectomyView official trial listing → -
Completed NCT NCT04074161
Research Study to Investigate How Well Semaglutide Works Compared to Liraglutide in People Living With Overweight or Obesity
Not yet reported Novo Nordisk A/S 338 participants Est. completion 2021-05-11 19 sitesOther conditions: Overweight, ObesityView official trial listing → -
Terminated NCT NCT04079881
Glucagon Response to Prandial Insulin Administration in Persons With Type 1 Diabetes
Not yet reported, Not yet reported Washington University School of Medicine 1 participants Est. completion 2020-07-01 1 siteOther conditions: Type 1 Diabetes, Hyperglycemia, PostprandialView official trial listing → -
Completed NCT NCT04081337
A Study to Measure Energy Expenditure and Food Intake in Participants With Obesity Using Tirzepatide
Not yet reported Eli Lilly and Company 55 participants Est. completion 2022-05-26 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT04093752
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes on Metformin With or Without Sulfonylurea (SURPASS-AP-Combo)
Not yet reported Eli Lilly and Company 917 participants Est. completion 2021-11-24 67 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04098549
The Effect of Rapid and Slow Glucose Fall on the Subsequent Glucose Production in People With Type 1 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 10 participants Est. completion 2020-01-15 1 siteOther conditions: Type 1 Diabetes, Blood Glucose, Low, Glucose Metabolism DisordersView official trial listing → -
Status unknown NCT NCT04122716
Combined Effects of GLP-1 Analogue and Exercise on Maintenance of Weight Loss and Health After Very-low Calorie Diet
Not yet reported Signe Torekov 215 participants Est. completion 2021-11 1 siteOther conditions: ObesityView official trial listing → -
Withdrawn NCT NCT04133922
Effect of GLP-1 on Microvascular Insulin Responses in Type 1 Diabetes
Not yet reported University of Virginia Est. completion 2024-10 1 siteOther conditions: Type 1 Diabetes, Insulin Sensitivity/ResistanceView official trial listing → -
Status unknown NCT NCT04137328
Clinical Study on the Improvement of Diabetic Neuropathic Pain by Liraglutide
Not yet reported Fudan University 60 participants Est. completion 2022-11-30Other conditions: Diabetic Neuropathic PainView official trial listing → -
Status unknown NCT NCT04146155
Efficacy and Safety of Liraglutide in Type 2 Diabetes With Lower Extremity Arterial Disease
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 200 participants Est. completion 2021-12-31 1 siteType 2 diabetes Other conditions: Peripheral Vascular Disorder Due to Diabetes MellitusView official trial listing → -
Completed NCT NCT04166773
A Study of Tirzepatide (LY3298176) in Participants With Nonalcoholic Steatohepatitis (NASH)
Not yet reported Eli Lilly and Company 190 participants Est. completion 2024-01-10 112 sitesMASHView official trial listing → -
Completed NCT NCT04172441
Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism
Not yet reported, Not yet reported Zealand Pharma 12 participants Est. completion 2022-03-07 6 sitesOther conditions: Congenital HyperinsulinismView official trial listing → -
Completed NCT NCT04172987
A Study of the Effect of Tirzepatide on How the Body Handles Birth Control Pills in Healthy Female Participants
Not yet reported Eli Lilly and Company 40 participants Est. completion 2021-02-09 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT04184622
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight
Not yet reported Eli Lilly and Company 2539 participants Est. completion 2024-07-06 118 sitesOther conditions: Overweight, ObesityView official trial listing → -
Status unknown NCT NCT04186026
Co-infusion of Neurotensin and GLP-1 Effects on Appetite and Food Intake.
Not yet reported University of Copenhagen 35 participants Est. completion 2024-06-30 2 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT04186494
Effect of Liraglutide vs CPAP on Cardiometabolic Outcomes in Obstructive Sleep Apnea
Not yet reported St Vincent's University Hospital, Ireland 30 participants Est. completion 2022-07-31 1 siteOther conditions: Sleep Apnea, ObstructiveView official trial listing → -
Withdrawn NCT NCT04192019
Micro Glucagon During Exercise in Type 1 Diabetes
Not yet reported Insel Gruppe AG, University Hospital Bern Est. completion 2024-06Other conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Completed NCT NCT04199728
Use of a GLP-1R Agonist to Treat Opioid Use Disorder
Not yet reported, Not yet reported Milton S. Hershey Medical Center 27 participants Est. completion 2023-09-13 1 siteOther conditions: Opiate Substitution Treatment, Opioid-Related DisordersView official trial listing → -
Status unknown NCT NCT04232605
Investigation of Vasodilation and Intensity of Headache Triggered by Glucagon Like Peptide-1 in Humans
Not yet reported Danish Headache Center 43 participants Est. completion 2022-01-01 1 siteOther conditions: Headache, MigraineView official trial listing → -
Completed NCT NCT04235959
A Study of Tirzepatide in Chinese Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 24 participants Est. completion 2021-08-17 2 sitesType 2 diabetesView official trial listing → -
Terminated NCT NCT04253223
A Study to Determine Safety and Efficacy of (REMD-477) in Controlling Hyperglycemia Due to Copanlisib
Not yet reported Duke University 1 participants Est. completion 2021-05-05 1 siteOther conditions: Hyperglycemia Drug InducedView official trial listing → -
Completed NCT NCT04255433
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 13299 participants Est. completion 2025-06-12 635 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04295005
A Study Based on Data From German Sick Funds That Looks at the Costs of Treatment of Type-2 Diabetic Patients With Empagliflozin vs. DPP-4 Inhibitors vs. GLP-1 Receptor Agonists
Boehringer Ingelheim 24500 participants Est. completion 2021-09-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04300049
Effect of Physiologic Hyperglucogonemia on Adipocyte Metabolism
Not yet reported The University of Texas Health Science Center at San Antonio 10 participants Est. completion 2023-11-15 2 sitesOther conditions: Insulin SensitivityView official trial listing → -
Status unknown NCT NCT04305002
Exenatide Treatment in Parkinson's Disease
Not yet reported Center for Neurology, Stockholm 60 participants Est. completion 2023-10-10 1 siteOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT04307797
Effect of Glucagon and Glucagon-like Peptide-1 Co-agonism on Cardiac Function and Metabolism in Overweight Participants with Type 2 Diabetes
Not yet reported Cambridge University Hospitals NHS Foundation Trust 10 participants Est. completion 2022-10-07 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT04311411
A Study of Tirzepatide in Overweight and Very Overweight Participants
Not yet reported Eli Lilly and Company 114 participants Est. completion 2022-12-16 3 sitesOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT04311424
Study of Tirzepatide in Healthy Participants
Not yet reported Eli Lilly and Company 6 participants Est. completion 2020-10-02 1 siteOther conditions: HealthyView official trial listing → -
Active, not recruiting NCT NCT04324229
Liraglutide in the Prevention of Type 2 Diabetes After Gestational Diabetes
Not yet reported Turku University Hospital 80 participants Est. completion 2027-12 1 siteOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT04325581
Laparocopic Sleeve Gastrectomy With or Without Liraglutide in Obese Patients
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 16 participants Est. completion 2018-12-31Other conditions: Weight LossView official trial listing → -
Terminated NCT NCT04330625
Glucagon Receptor Inhibition to Enable Breast Cancer Patients to Benefit From PI3K Inhibitor Therapy (REMD-477)
Not yet reported Duke University 1 participants Est. completion 2021-05-05 1 siteOther conditions: Hyperglycemia Drug InducedView official trial listing → -
Completed NCT NCT04334161
Evaluation of the Neuro-endocrine Response to Post-prandial Hyperinsulinaemic Hypoglycaemia.
Lia Bally 32 participants Est. completion 2021-07-13 1 siteOther conditions: Roux-en-y Gastric Bypass, Post Prandial HypoglycemiaView official trial listing → -
Completed NCT NCT04337268
Acute Effects of GLP-1 on Renal Hemodynamics
Not yet reported Copenhagen University Hospital, Rigshospitalet 10 participants Est. completion 2020-03-01 1 siteOther conditions: The GLP-1-mediated Gut-kidney AxisView official trial listing → -
Completed NCT NCT04347252
Glucagon Regulation of Glucose Metabolism
Not yet reported David D'Alessio, M.D. 19 participants Est. completion 2021-04-16 1 siteOther conditions: Insulin SecretionView official trial listing → -
Completed NCT NCT04352738
Role of the Liver in Glucose Homeostasis Using Metabolic Imaging
Insel Gruppe AG, University Hospital Bern 30 participants Est. completion 2022-08-30 1 siteOther conditions: Type 1 Diabetes, Bariatric Surgery CandidateView official trial listing → -
Completed NCT NCT04354090
Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of JY09
Not yet reported Beijing Dongfang Biotech Co., Ltd. 41 participants Est. completion 2019-06-22 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT04355832
Glucagon-like Peptide-1 in Type 1 Diabetes
Not yet reported University of Maryland, Baltimore Est. completion 2025-09-24 1 siteOther conditions: Type1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04373967
Study to Assess the Efficacy and Safety of Liraglutide in the Treatment of Type 2 Diabetes
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 424 participants Est. completion 2021-12-02 46 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT04379856
Proof of Concept Study in Patients With Short Bowel Syndrome
Not yet reported, Not yet reported 9 Meters Biopharma, Inc. 12 participants Est. completion 2020-12-31 1 siteOther conditions: Short Bowel SyndromeView official trial listing → -
Status unknown NCT NCT04383197
Exercise and GLP-1 RA on Insulin Secretion
Not yet reported University of Copenhagen 30 participants Est. completion 2022-08 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04388059
Antrum Size, Glucagon-like Peptide 1 Levels and Glycemic Control After Sleeve Gastrectomy in Morbid Obese Diabetic Adolescents
Tanta University 18 participants Est. completion 2015-12Other conditions: Adolescent ObesityView official trial listing → -
Completed NCT NCT04392843
Effect of Fasting on Insulin-induced Hypoglycemia Counterregulation in Healthy Humans
Not yet reported University of Cincinnati 12 participants Est. completion 2023-05-11 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT04407234
A Study to Measure Stomach Emptying in Overweight Non-diabetic and Diabetic Participants Using Tirzepatide
Not yet reported Eli Lilly and Company 36 participants Est. completion 2021-01-07 1 siteType 2 diabetes Other conditions: Overweight, ObesityView official trial listing → -
Withdrawn NCT NCT04410341
The DPP-4 Inhibitor Vildagliptin as Adjunct in Major Depressive Disorder Patients
Not yet reported, Not yet reported Sadat City University Est. completion 2024-12-01 1 siteOther conditions: Major Depressive DisorderView official trial listing → -
Completed NCT NCT04416737
Evaluating the Benefits of Physiologic Insulin Delivery
Not yet reported Stanford University 16 participants Est. completion 2023-06-02 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT04428866
Mechanisms of Post-Bariatric Hypoglycemia
Joslin Diabetes Center 105 participants Est. completion 2024-09 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT04432090
GPR119 Agonist for Hypoglycemia in Type 1 Diabetes
Not yet reported AdventHealth Translational Research Institute 110 participants Est. completion 2023-08-12 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT04459338
A Dose-response Study Examining the Contribution of GLP-1 Receptor Signaling to Glucagon-stimulated Insulin Secretion
Not yet reported Adrian Vella 11 participants Est. completion 2022-06-14 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT04461015
The Effect of the Interaction of Glucagon and Insulin on Endogenous Glucose Production in Humans
Not yet reported Adrian Vella 12 participants Est. completion 2022-01-06 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT04487743
Efficacy and Safety of Liraglutide on Body Weight in Obese Subjects or Overweight Subjects With Co-morbidities
Not yet reported Xiangya Hospital of Central South University 300 participants Est. completion 2022-06 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT04504370
Safety and Efficacy of Pegylated Exenatine Injection (PB-119) in Drug-naïve T2DM Subjects
Not yet reported PegBio Co., Ltd. 273 participants Est. completion 2022-11-28 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04504396
Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy
Not yet reported PegBio Co., Ltd. 620 participants Est. completion 2023-05-26 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04520490
Brain Activation and Satiety in Children 2
Not yet reported Seattle Children's Hospital 63 participants Est. completion 2026-02-12 1 siteOther conditions: Childhood ObesityView official trial listing → -
Status unknown NCT NCT04525300
Gut Microbiome Changes Following Liraglutide Treatment in Obese Subjects or Overweight Subjects With Co-morbidities
Not yet reported Xiangya Hospital of Central South University 300 participants Est. completion 2022-06 1 siteOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT04529278
Efficacy and Tolerance of Liraglutide for Weight Loss in Obese Type 2 Diabetic Hemodialysis Patients
Not yet reported Fondation Hôpital Saint-Joseph 18 participants Est. completion 2023-12-31 4 sitesType 2 diabetes Other conditions: Hemodialysis, ObeseView official trial listing → -
Terminated NCT NCT04531176
EMI-EHP Weight Management and Type 2 Diabetes Pragmatic Trial
Not yet reported The Cleveland Clinic 74 participants Est. completion 2023-08-04 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Status unknown NCT NCT04535960
Incretin and Treatment With Inhibition of Sodium-glucose Cotransporter-2 Combination Insights Into Mechanisms Implicated in Congestive Heart Failure: "NATRIURETIC" Trial
Not yet reported University Health Network, Toronto 36 participants Est. completion 2023-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04537923
A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin
Not yet reported Eli Lilly and Company 1428 participants Est. completion 2022-11-01 135 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04545411
Combination GRA and SGLT-2i Treatment in Type 1 Diabetes
Not yet reported, Not yet reported University of California, San Diego 12 participants Est. completion 2022-10-31 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT04550520
Copeptin After a Subcutaneous Stimulation With Glucagon in Adults
Not yet reported University Hospital, Basel, Switzerland 42 participants Est. completion 2021-05-30 1 site Stand-aloneOther conditions: Diabetes InsipidusView official trial listing → -
Status unknown NCT NCT04575194
Study of the Cardiometabolic Effects of Obesity Pharmacotherapy
Not yet reported National and Kapodistrian University of Athens 40 participants Est. completion 2023-05-30 1 siteOther conditions: Obesity, Blood PressureView official trial listing → -
Completed NCT NCT04605861
The Efficacy and Safety of Liraglutide on Body Weight Loss in Obese and Overweight Patients
Not yet reported Shanghai Zhongshan Hospital 414 participants Est. completion 2023-04-15 1 siteOther conditions: Obese, OverweightView official trial listing → -
Completed NCT NCT04610203
Glycaemic Response, Insulinaemic Response, GLP-1 and GIP Testing of Food Product Lines
Not yet reported Oxford Brookes University 41 participants Est. completion 2019-09-30 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT04614168
Maximising Time With a Normal Blood Glucose to Restore the Glucagon Response in Type 1 Diabetes
Not yet reported University of Edinburgh 24 participants Est. completion 2025-12-26 1 siteOther conditions: Type 1 Diabetes, Type 1 Diabetes Mellitus With Hypoglycemia, Hypoglycemia, Hypoglycemia Unawareness, Glucagon Deficiency, Insulin HypoglycemiaView official trial listing → -
Withdrawn NCT NCT04643301
Liraglutide for Low-responders After Bariatric Surgery
Not yet reported Zuyderland Medisch Centrum Est. completion 2021-12-31Other conditions: Obesity, Obesity, MorbidView official trial listing → -
Completed NCT NCT04651868
The Effect of Exogenous Glucagon-like Peptide 2 on Cholecystokinin-induced Gallbladder Emptying
Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2021-04-27 1 siteOther conditions: GallbladderView official trial listing → -
Completed NCT NCT04657003
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight
Not yet reported Eli Lilly and Company 938 participants Est. completion 2023-04-10 75 sitesType 2 diabetes Other conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT04657016
A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
Not yet reported Eli Lilly and Company 579 participants Est. completion 2023-05-12 65 sitesOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT04657939
Targeting Beta-cell Failure in Lean Patients With Type 2 Diabetes
Not yet reported University of Leeds 57 participants Est. completion 2022-10-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04660643
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight for the Maintenance of Weight Loss
Not yet reported Eli Lilly and Company 783 participants Est. completion 2023-05-18 70 sitesOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT04666987
A Research Study Looking at Long-term Blood Sugar Control in People With Type 2 Diabetes Being Treated With Xultophy® in a Real-world Setting in Italy
Novo Nordisk A/S 359 participants Est. completion 2023-02-10 28 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT04683237
Liraglutide Plus Megestrol Acetate in Endometrial Atypical Hyperplasia
Not yet reported, Not yet reported Xiaojun Chen Est. completion 2026-11-30Other conditions: Atypical Endometrial Hyperplasia, Obese, Fertility IssuesView official trial listing → -
Completed NCT NCT04687514
Effects of Glucagon-Like Peptide-1 Analogs on Sexuality
Not yet reported University Hospital, Basel, Switzerland 26 participants Est. completion 2022-09-05 1 siteOther conditions: Sexual FunctioningView official trial listing → -
Completed NCT NCT04702672
High-amylose Barley (HIAMBA) in the Regulation and Prevention of Type 2 Diabetes
Not yet reported University of Aarhus 38 participants Est. completion 2024-07-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04712266
A Trial to Investigate Hyperglycemic and Hypoglycemic Excursions in Subjects With Type 1 Diabetes
Not yet reported Abvance Therapeutics 15 participants Est. completion 2021-01-10 1 siteOther conditions: Type 1 Diabetes Mellitus With HypoglycemiaView official trial listing → -
Status unknown NCT NCT04733508
Glucagon Like Peptide 1 Receptor (GLP1R) Expression and Beta-cell Mass in Patients With Type 2 Diabetes
Not yet reported Radboud University Medical Center 28 participants Est. completion 2022-12-01 1 siteType 2 diabetes Other conditions: Diabetes MellitusView official trial listing → -
Withdrawn NCT NCT04758858
Carbohydrates Under Target for Type 1 Diabetes Management
Not yet reported Institut de Recherches Cliniques de Montreal Est. completion 2023-03 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Terminated NCT NCT04763564
Efficacy of Liraglutide Therapy in Patients With IPAA
Not yet reported University of North Carolina, Chapel Hill 8 participants Est. completion 2023-10-16 1 siteOther conditions: Pouchitis, Irritable Pouch SyndromeView official trial listing → -
Active, not recruiting NCT NCT04775082
SCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With Obesity
Not yet reported Novo Nordisk A/S 78 participants Est. completion 2027-02-08 32 sitesOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT04779645
Effects of GRA in Patients With Type 1
Not yet reported University of California, San Diego 30 participants Est. completion 2025-12-31 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT04781998
Is Saxenda® a Viable Treatment of Obese Patients in Forensic Psychiatry?
Not yet reported Anders Fink-Jensen, MD, DMSci 24 participants Est. completion 2022-09-01 1 siteOther conditions: Mental Disorder, Metabolic Disturbance, Feasibility, Overweight and Obesity, LiraglutideView official trial listing → -
Completed NCT NCT04809311
Remote Study Collecting Blood Glucose Values and Activity Data in Patients With Type 2 Diabetes on Different Treatments
Novo Nordisk A/S 156 participants Est. completion 2025-01-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04825366
Restoration of Hypoglycemia Awareness With Home-based High Intensity Interval Training
Not yet reported Institut de Recherches Cliniques de Montreal 47 participants Est. completion 2025-08-31 1 siteOther conditions: Type 1 Diabetes, Hypoglycemia UnawarenessView official trial listing → -
Completed NCT NCT04829903
Dulaglutide Versus Liraglutide in Obese Type 2 Diabetic Adolescents Using Metformin
Not yet reported Corporacion Parc Tauli 116 participants Est. completion 2021-11-20 1 siteType 2 diabetes Other conditions: Obesity, Adolescent ObesityView official trial listing → -
Withdrawn NCT NCT04839237
The Effect and the Pharmacogenomics Study of Liraglutide in Obese Patients
Not yet reported Xiangya Hospital of Central South University Est. completion 2021-12-01 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT04844918
A Study of Tirzepatide (LY3298176) in Participants With Obesity Disease
Not yet reported Eli Lilly and Company 267 participants Est. completion 2023-06-24 18 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT04847557
A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial
Not yet reported Eli Lilly and Company 731 participants Est. completion 2024-07-02 146 sitesHeart failure Other conditions: ObesityView official trial listing → -
Completed NCT NCT04859322
The Effect of Lifestyle-induced Hepatic Steatosis on Glucagon-stimulated Amino Acid Turnover
Not yet reported Malte Palm Suppli, MD 20 participants Est. completion 2021-12-09 1 siteOther conditions: Non-Alcoholic Fatty Liver Disease, Glucagon ResistanceView official trial listing → -
Completed NCT NCT04876027
GLP-1 RAs in Patients With Polycystic Ovary Syndrome (PCOS)
Not yet reported Shanghai 10th People's Hospital 68 participants Est. completion 2022-05-10 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04881110
Liraglutide and Peripheral Artery Disease
Not yet reported University of Campania Luigi Vanvitelli 60 participants Est. completion 2022-12-31 1 siteType 2 diabetes Other conditions: Peripheral Arterial DiseaseView official trial listing → -
Completed NCT NCT04883346
Liraglutide (Saxenda(R)) in Adolescents With Obesity After Sleeve Gastrectomy
Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 34 participants Est. completion 2024-04-30 1 siteOther conditions: Obesity, Status Post Sleeve GastrectomyView official trial listing → -
Withdrawn NCT NCT04885634
Semaglutide for the Reduction of Arrhythmia Burden in Overweight AF Patients
Not yet reported Axel Brandes Est. completion 2024-11Other conditions: Atrial Fibrillation, Overweight and ObesityView official trial listing → -
Status unknown NCT NCT04892199
Does GLP-1RA Prevent Deterioration of Metabolic State in Prediabetic and Diabetic Patients Treated With Antipsychotic Medication?
Not yet reported Anders Fink-Jensen, MD, DMSci 104 participants Est. completion 2026-08-01 3 sitesType 2 diabetes Other conditions: Metabolic Disturbance, Schizophrenia, Clozapine, GLP-1, OlanzapineView official trial listing → -
Completed NCT NCT04903509
A Study in Men With Overweight to Test How Well Different Doses of BI 1820237 Are Tolerated When Given as an Injection Alone or in Combination With Liraglutide
Not yet reported Boehringer Ingelheim 95 participants Est. completion 2022-08-26 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT04904133
Effects of Low/No Calorie Sweeteners on Glucose Tolerance
Not yet reported Acibadem University 42 participants Est. completion 2019-07-02 1 siteOther conditions: Healthy Population, Glucose ToleranceView official trial listing → -
Completed NCT NCT04907721
Development and Evaluation of a Glucagon Sensitivity Test in Individuals With and Without Hepatic Steatosis
Not yet reported University of Copenhagen 65 participants Est. completion 2023-10-21 1 siteOther conditions: Non-Alcoholic Fatty Liver Disease, Glucagon Resistance, Type 1 Diabetes, ObesityView official trial listing → -
Completed NCT NCT04926415
Effects of Transcutaneous Auricular Vagus Nerve Stimulation on Obesity and Insulin Resistance
Not yet reported Burrell College of Health Sciences 30 participants Est. completion 2022-04-26 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT04949867
Dual-Hormone Closed-Loop Glucose Control in Adolescents With Type 1 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 11 participants Est. completion 2022-04-26 2 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT04952779
Regulatory Post Marketing Surveillance (rPMS) Study of Xultophy® (Insulin Degludec/Liraglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea
Novo Nordisk A/S 750 participants Est. completion 2024-12-15 32 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04977635
Biomarkers of Heterogeneity in Type 1 Diabetes
Diabeter Nederland BV 611 participants Est. completion 2021-12-31 3 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT04992312
A Study of Nasal Glucagon (LY900018) in Pediatric Participants With Type 1 Diabetes
Not yet reported Eli Lilly and Company 7 participants Est. completion 2023-11-05 8 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT05005741
The Effects of Glucose Control and Weight Loss Between Beinaglutide and Dulaglutide in Type 2 Diabetes With Overweight or Obesity.
Not yet reported Second Xiangya Hospital of Central South University 120 participants Est. completion 2023-12-31 4 sitesType 2 diabetes Other conditions: Overweight or ObesityView official trial listing → -
Terminated NCT NCT05007977
Effect of ZT-01 on Glucagon During Hypoglycemia in Type 1 Diabetes Mellitus
Not yet reported Zucara Therapeutics Inc. 24 participants Est. completion 2022-04-18 1 siteOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Active, not recruiting NCT NCT05018286
Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.
Not yet reported VectivBio AG 158 participants Est. completion 2027-10-30 66 sitesOther conditions: Short Bowel SyndromeView official trial listing → -
Completed NCT NCT05024032
A Study of Tirzepatide (LY3298176) in Chinese Participants Without Type 2 Diabetes Who Have Obesity or Overweight (SURMOUNT-CN)
Not yet reported Eli Lilly and Company 210 participants Est. completion 2022-12-27 29 sitesOther conditions: Obesity, Overweight, Metabolism and Nutrition DisorderView official trial listing → -
Completed NCT NCT05029076
Human Bioequivalence Test of Liraglutide Injection
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 28 participants Est. completion 2019-07-01 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05041673
Anti-diabetic Drugs and Fatty Liver Management
Not yet reported Alexandria University 120 participants Est. completion 2022-09-30 1 siteType 2 diabetes Other conditions: Fatty Liver, NonalcoholicView official trial listing → -
Completed NCT NCT05056584
The Role of the Kidneys and Liver in the Elimination of Glucagon
Not yet reported University Hospital, Gentofte, Copenhagen 48 participants Est. completion 2023-03-28 1 siteChronic kidney disease Other conditions: Liver Cirrhosis, HyperglucagonemiaView official trial listing → -
Completed NCT NCT05073692
Comparison of Type 2 Diabetes Pharmacotherapy Regimens
Kaiser Permanente 241981 participants Est. completion 2025-03-12 6 sitesType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT05076292
Low-dose Glucagon for Prevention of Exercise-Induced Hypoglycemia in People With Type 1 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 22 participants Est. completion 2023-08-08 1 site Stand-aloneOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Completed NCT NCT05093517
Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM
Not yet reported The University of Texas Health Science Center at San Antonio 4 participants Est. completion 2022-03-16 1 siteType 2 diabetes Other conditions: Glucose Tolerance Impaired, Insulin SensitivityView official trial listing → -
Status unknown NCT NCT05095259
Metabolic Adaptation to High-frequent Hypoglycaemia in Type 1 Diabetes
Not yet reported Nordsjaellands Hospital 60 participants Est. completion 2023-12 2 sitesOther conditions: Type1diabetesView official trial listing → -
Completed NCT NCT05111912
Effects of XW003 Versus Liraglutide on Body Weight of Adult Participants With Obesity
Not yet reported Sciwind Biosciences APAC CO Pty. Ltd. 206 participants Est. completion 2022-12-20 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT05153590
A Research Study About Weight Loss and Treatment Patterns With the Use of Saxenda® in Adults in Real-life Settings in Switzerland
Novo Nordisk A/S 269 participants Est. completion 2022-04-15 1 siteOther conditions: Obesity or OverweightView official trial listing → -
Status unknown NCT NCT05161429
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
Brigham and Women's Hospital 550000 participants Est. completion 2024-06-30 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05162183
Replication of the LEAD-2 Diabetes Trial in Healthcare Claims Data
Brigham and Women's Hospital 3474 participants Est. completion 2021-09-01 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT05177653
Separate and Combined Extrapancreatic Effects of the Incretin Hormones
Not yet reported University Hospital, Gentofte, Copenhagen 13 participants Est. completion 2023-03-03 1 siteOther conditions: Pancreatectomy; HyperglycemiaView official trial listing → -
Status unknown NCT NCT05181150
Gut Peptides and Bone Remodeling in Individuals With Spinal Cord Injury
Not yet reported University of Copenhagen 20 participants Est. completion 2024-11 1 siteOther conditions: Spinal Cord InjuriesView official trial listing → -
Completed NCT NCT05193578
Home-based Intervention With Semaglutide Treatment Of Neuroleptica-Related Prediabetes
Not yet reported Jan Frystyk 154 participants Est. completion 2024-05-01 1 siteOther conditions: Schizophrenia, Prediabetic StateView official trial listing → -
Active, not recruiting NCT NCT05202353
A Study in People With Obesity to Test the Effects of BI 456906 Compared With Semaglutide on Glucagon Receptor Activity in the Liver
Not yet reported Boehringer Ingelheim 29 participants Est. completion 2027-02-03 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT05203237
Phase 1 Study to Evaluate the Safety and Tolerability of VK2735
Not yet reported Viking Therapeutics, Inc. 92 participants Est. completion 2024-12-03 1 siteMASH Other conditions: Weight LossView official trial listing → -
Completed NCT NCT05205928
Weekly Subcutaneous Semaglutide as Adjunct to Closed-loop Therapy in Type 1 Diabetes Care
Not yet reported, Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 28 participants Est. completion 2024-06-30 1 siteOther conditions: Type 1 Diabetes, Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT05206149
Stimulation Test With Intranasal Glucagon for Corticotroph, Somatotroph and Antidiuretic Axes
Not yet reported A.O.U. Città della Salute e della Scienza 10 participants Est. completion 2021-12-31 1 siteOther conditions: HypopituitarismView official trial listing → -
Completed NCT NCT05214573
Second-line Therapies for Patients With Type 2 Diabetes and Moderate Cardiovascular Disease Risk
Mayo Clinic 386301 participants Est. completion 2025-07-22 1 siteType 2 diabetes Other conditions: Cardiac DiseaseView official trial listing → -
Completed NCT NCT05218915
Basal Plus GLP1-ra on Glycemic Variability in CKD
Not yet reported Elaine Chow 95 participants Est. completion 2024-10-30 1 siteChronic kidney disease Other conditions: Diabetes MellitusView official trial listing → -
Active, not recruiting NCT NCT05220917
Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study
Brigham and Women's Hospital 781430 participants Est. completion 2027-09-30 1 siteType 2 diabetes Other conditions: Cardiovascular Events, Renal DiseaseView official trial listing → -
Active, not recruiting NCT NCT05221229
Outcome of Overweight AF Patients Following Ablation With a Potential Weight Loss Medication ( GOAL-AF )
University Hospital Birmingham 29 participants Est. completion 2026-06-01 1 siteOther conditions: Atrial Fibrillation, Recurrence, Overweight and Obesity, LiraglutideView official trial listing → -
Completed NCT NCT05225974
A Randomized Phase 1 Study of Liralutide Injection in Healthy Chinese Subjects
Not yet reported The Affiliated Hospital of Qingdao University 32 participants Est. completion 2021-08-19 1 siteOther conditions: Therapeutic EquivalencyView official trial listing → -
Status unknown NCT NCT05249881
"Efficacy of Once Weekly GLP 1 Analogue: Semaglutide. A Multicenter Experience From Pakistan."
Not yet reported Aga Khan University 300 participants Est. completion 2022-12 2 sitesType 2 diabetes Other conditions: Weight Change, BodyView official trial listing → -
Active, not recruiting NCT NCT05254314
Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3)
Not yet reported Vanderbilt University Medical Center 100 participants Est. completion 2026-12-30 1 siteOther conditions: AsthmaView official trial listing → -
Completed NCT NCT05254418
Effects of GLP1-RA on Ectopic Fat Deposition in Chronic Kidney Disease
Not yet reported Vanderbilt University Medical Center 7 participants Est. completion 2024-08-01 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT05260021
A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both
Not yet reported Eli Lilly and Company 99 participants Est. completion 2025-01-28 51 sitesType 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders, Endocrine System Diseases, Metabolic DiseaseView official trial listing → -
Active, not recruiting NCT NCT05264727
Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion
Not yet reported Mayo Clinic 30 participants Est. completion 2026-12-31 1 siteType 2 diabetes Other conditions: Healthy, ObesityView official trial listing → -
Status unknown NCT NCT05268627
Endoscopic Ultrasound Guided Gastric Botulinum Toxin Injections Versus Glucagon Like Peptide 1 Receptor Agonist in Weight Loss
Not yet reported Mansoura University 38 participants Est. completion 2023-01-27 2 sitesOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT05285397
Effect of Liraglutide on Weight Loss in Patients Who Have Undergone Revisional Bariatric Surgeries.
Not yet reported General Committee of Teaching Hospitals and Institutes, Egypt 60 participants Est. completion 2022-09 1 siteOther conditions: Morbid ObesityView official trial listing → -
Completed NCT NCT05290506
Linagliptin Response to OGTT in Prediabetes and Type 2 Diabetes Mellitus
Not yet reported National University of Malaysia 50 participants Est. completion 2021-03-01 1 sitePrediabetesType 2 diabetesView official trial listing → -
Completed NCT NCT05294536
A Pharmacokinetic Study Comparing the Liraglutide Injection (RD12014) and Victoza® in Healthy Chinese Subjects
Not yet reported Sunshine Lake Pharma Co., Ltd. 50 participants Est. completion 2020-11-27 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05310292
A Glucometabolic Evaluation of Patients With Idiopathic Ketotic Hypoglycemia
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2025-04-01 1 siteOther conditions: Idiopathic Ketotic HypoglycemiaView official trial listing → -
Completed NCT NCT05313529
LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 396 participants Est. completion 2026-07-01 5 sitesType 2 diabetes Other conditions: Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT05360147
Liraglutide Improve Cognitive Function in Patients With Type 2 Diabetes Mellitus
Not yet reported Third Military Medical University 30 participants Est. completion 2021-05-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05379686
Glucagon and Advanced HCL System to Prevent Exercise-Induced Hypoglycaemia in People With Type 1 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 10 participants Est. completion 2024-05-13 1 site Stand-aloneOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Status unknown NCT NCT05389813
Comparison Between Oxycodone and Pregabalin as Preemptive Analgesia
Not yet reported, Not yet reported An-Najah National University 150 participants Est. completion 2024-05-01 1 siteOther conditions: AnesthesiaView official trial listing → -
Completed NCT NCT05390307
Obesity Treatment to Improve Diabetes
Not yet reported Dasman Diabetes Institute 60 participants Est. completion 2024-01-01 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05391581
The Role of GIP and GLP-2 in Postprandial Splanchnic Blood Flow Distribution and Metabolism
Not yet reported University of Copenhagen 10 participants Est. completion 2023-02-07 1 siteOther conditions: Blood FlowView official trial listing → -
Completed NCT NCT05395000
Comparison of Ease of Use and Acceptability of Intranasal and Injectable Glucagon Among Providers Administering it to Children or Adolescents With Type 1 Diabetes (BETTER-ING)
Not yet reported CHU de Quebec-Universite Laval 60 participants Est. completion 2022-09-22 1 siteOther conditions: Diabetes Mellitus, Type 1, HypoglycemiaView official trial listing → -
Completed NCT NCT05412004
Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstructive Sleep Apnea
Not yet reported Eli Lilly and Company 469 participants Est. completion 2024-03-29 58 sitesObstructive sleep apnea Other conditions: ObesityView official trial listing → -
Terminated NCT NCT05415410
Proof-of-concept Trial of Apraglutide in Acute Graft Versus Host Disease (aGVHD)
Not yet reported VectivBio AG 31 participants Est. completion 2024-12-17 13 sitesOther conditions: GVHDView official trial listing → -
Completed NCT NCT05419856
Safety, Tolerability and Pharmacokinetics of Intraarticular 4P004 Single Dose in Patient With KL 2-4 Osteoarthritic Knee
Not yet reported 4Moving Biotech 34 participants Est. completion 2023-10-31 3 sitesOsteoarthritisView official trial listing → -
Active, not recruiting NCT NCT05433584
A Study of Tirzepatide Compared With Intensified Conventional Care in Adult Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 780 participants Est. completion 2027-11 90 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT05438186
INSPIRE Turkey :A Research Study Looking at the Clinical Parameters Associated With Use and Discontinuation of Saxenda® in Local Clinical Practice in Turkey by Analysing Past Patient Medical Records
Novo Nordisk A/S Est. completion 2022-10-31 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT05444569
A Study of LY3537021 in Healthy Participants
Not yet reported Eli Lilly and Company 47 participants Est. completion 2023-02-24 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT05446415
L-Cell Activity in Small Intestine as Biliopancreatic Loop in Obese Patients With DM2 Submitted to RYGBP
Not yet reported University of Sao Paulo General Hospital 20 participants Est. completion 2022-12-05 1 siteType 2 diabetes Other conditions: Severe ObesityView official trial listing → -
Withdrawn NCT NCT05454709
A Stable Glucagon Analog Administered by a Bihormonal Closed Loop System
Not yet reported Inreda Diabetic B.V. Est. completion 2023-12-29 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT05467514
Effect of Liraglutide on Subclinical Atherosclerosis in Patients With Type 1 Diabetes Mellitus
Not yet reported David Sanchez Garcia 35 participants Est. completion 2023-02-28 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT05468632
A Study in North Macedonia Investigating Retrospective Data of Glucagon-like Peptide-1 (GLP-1) Participants With Type 2 Diabetes (T2D) in Real World Environment (RWE) Setting (MIRAGE)
Novo Nordisk A/S 314 participants Est. completion 2022-07-31 17 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT05492305
Glucagon-like Peptide 1 (GLP1) Receptor Agonists and Mental Health
King's College London 20 participants Est. completion 2023-08 1 siteOther conditions: Diabetes Mellitus, Obesity, Mental Health IssueView official trial listing → -
Completed NCT NCT05500586
The Effects of Glucagon on Hepatic Metabolism
Not yet reported, Not yet reported Adrian Vella 21 participants Est. completion 2026-03-31 1 siteMASLD Other conditions: Obesity, Type2diabetesView official trial listing → -
Completed NCT NCT05526157
An Observational Study, Called FINEGUST, to Learn More About How People With Chronic Kidney Disease and Type 2 Diabetes Are Treated and How the Introduction of New Treatment Options, Like Finerenone, Impacts Clinical Practice
Bayer 50000 participants Est. completion 2024-09-05 5 sitesChronic kidney diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT05535322
Real-world Evaluation of GLP-1 Receptor Agonists (GLP-1RA) on Efficacy and Persistence, Adherence and Therapeutic Inertia Among Type 2 Diabetes Adults With Obesity
Ana Palanca 26944 participants Est. completion 2022-09-01 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT05536804
A Study of Tirzepatide (LY3298176) in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes
Not yet reported Eli Lilly and Company 134 participants Est. completion 2026-07-30 27 sitesChronic kidney diseaseType 2 diabetes Other conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT05543850
Portable Artificial Pancreas Applied for Youth and Adolescents
Not yet reported Inreda Diabetic B.V. 20 participants Est. completion 2023-05-19 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT05548647
Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects
Not yet reported University of Pennsylvania 120 participants Est. completion 2025-05-12 1 siteOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT05556512
A Study of Tirzepatide (LY3298176) on the Reduction on Morbidity and Mortality in Adults With Obesity
Not yet reported Eli Lilly and Company 15374 participants Est. completion 2027-10 671 sitesOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT05564039
A Study of Tirzepatide (LY3298176) in Adult Participants With Type 2 Diabetes Switching From Dulaglutide (SURPASS-SWITCH)
Not yet reported Eli Lilly and Company 282 participants Est. completion 2024-08-12 38 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT05579249
A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in America
Not yet reported Novo Nordisk A/S 500 participants Est. completion 2024-11-27 1 siteOther conditions: ObesityView official trial listing → -
Terminated NCT NCT05579977
Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People With Obesity
Not yet reported Pfizer 902 participants Est. completion 2023-09-22 90 sitesOther conditions: Diabetes Mellitus, ObesityView official trial listing → -
Completed NCT NCT05582096
A Study of LY3457263 in Obese Participants
Not yet reported Eli Lilly and Company 38 participants Est. completion 2023-06-08 1 siteOther conditions: Overweight, ObesityView official trial listing → -
Completed NCT NCT05598008
Effects of Glucagon-like-Peptide-1 Analogues on Sexuality
University Hospital, Basel, Switzerland 85 participants Est. completion 2025-10-24 1 siteOther conditions: Sexual DesireView official trial listing → -
Status unknown NCT NCT05606471
Glucagon-like Peptide-1 Agonism With Very Low Calorie Diets
Not yet reported University of Nottingham 45 participants Est. completion 2023-07-28 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05616013
Safety and Efficacy of Bimagrumab and Semaglutide in Adults Who Are Overweight or Obese
Not yet reported Eli Lilly and Company 507 participants Est. completion 2025-06-14 26 sitesOther conditions: Obesity, Obese, Overweight or ObesityView official trial listing → -
Completed NCT NCT05616273
Stimulated Glucagon as a Biomarker of Hypoglycemic Risk in Type 1 Diabetes
University of Exeter 62 participants Est. completion 2025-09-30 1 siteOther conditions: Type 1 Diabetes, HypoglycemiaView official trial listing → -
Status unknown NCT NCT05659368
Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1
Not yet reported Ospedale San Raffaele 10 participants Est. completion 2024-12 1 siteOther conditions: Wolfram SyndromeView official trial listing → -
Completed NCT NCT05663164
Effect of Thiamine on Serum Glucagon And Reactive Oxygen Species (ROS)
Not yet reported Universitas Sumatera Utara 30 participants Est. completion 2022-12-01 1 siteOther conditions: Sepsis, Thiamine DeficiencyView official trial listing → -
Terminated NCT NCT05668936
A Thorough QTC Study to Assess the Effect of Cotadutide on Cardiac Repolarization in Healthy Participants
Not yet reported AstraZeneca 31 participants Est. completion 2023-03-10 1 siteOther conditions: Non-alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT05669547
Dual Hormone Closed Loop in Type 1 Diabetes
Not yet reported UMC Utrecht 243 participants Est. completion 2025-10-15 14 sitesOther conditions: Diabetes Mellitus, Type 1, Diabetes type1, DiabetesView official trial listing → -
Completed NCT NCT05670379
Assessment of Safety, Tolerability and Drug Levels of Exenatide Implant
Not yet reported Vivani Medical, Inc 24 participants Est. completion 2025-08-21 1 siteOther conditions: Overweight and Obesity, Type2diabetesView official trial listing → -
Completed NCT NCT05680129
A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Dulaglutide in Participants With T2DM
Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 623 participants Est. completion 2024-10-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05680155
A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Placebo in T2DM Patients
Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 211 participants Est. completion 2024-10-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05691712
A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 257 participants Est. completion 2024-07-01 25 sitesOther conditions: Diabetes Type 2, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease, Endocrine System DiseasesView official trial listing → -
Terminated NCT NCT05694741
A Study to Assess Safety, Tolerability, and Pharmacokinetics of AZD0186
Not yet reported AstraZeneca 31 participants Est. completion 2023-05-10 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05696366
Combination Adjunctive Therapy to Address Multiple Metabolic Imbalances in Type 1 Diabetes
Not yet reported, Not yet reported University of California, San Diego 24 participants Est. completion 2028-01 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05696847
A Study of Tirzepatide (LY3298176) in Pediatric Participants With Obesity
Not yet reported Eli Lilly and Company 28 participants Est. completion 2025-01-16 3 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT05700604
Hypoglycemia and Glucagon Response in CF
Marmara University 53 participants Est. completion 2020-12-31 1 siteOther conditions: Cystic Fibrosis, Hypoglycemia, Glucagon Deficiency, Pancreatic InsufficiencyView official trial listing → -
Status unknown NCT NCT05705388
POSE2.0 With GLP-1 Agonist for Obesity Management
Not yet reported Emirates Health Services (EHS) 50 participants Est. completion 2026-01-03 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT05706506
A Study of Tirzepatide (LY3298176) in Adults With Type 2 Diabetes Switching From a GLP-1 RA (SURPASS-SWITCH-2)
Not yet reported Eli Lilly and Company 152 participants Est. completion 2023-10-31 32 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05724134
Pancreatic Clamp in NAFLD
Not yet reported Columbia University 18 participants Est. completion 2025-09-24 1 siteOther conditions: Insulin Resistance, Prediabetic State, Hyperinsulinemia, Non-Alcoholic Fatty Liver Disease, ObesityView official trial listing → -
Completed NCT NCT05725681
Satiety of High-Protein Ramen Noodles
Not yet reported Texas Tech University 30 participants Est. completion 2023-12-02 1 siteOther conditions: Appetitive BehaviorView official trial listing → -
Status unknown NCT NCT05751720
Effect on Non-Alcoholic Fatty Liver Disease in Patients With Type 2 Diabetes Mellitus With Gastric Inhibitory Polypeptide/Glucagon Like Peptide-1 Analogue
Not yet reported, Not yet reported Dr Adnan Agha 30 participants Est. completion 2025-02 1 siteType 2 diabetes Other conditions: Non-Alcoholic Fatty Liver Disease, Non-alcoholic Steatohepatitis, Liver FatView official trial listing → -
Active, not recruiting NCT NCT05756764
Anti-obesity Pharmacotherapy and Inflammation
Louisiana State University Health Sciences Center in New Orleans 30 participants Est. completion 2026-02-20 2 sitesOther conditions: ObesityView official trial listing → -
Terminated NCT NCT05762744
Pharmacogenomics of GLP1 Receptor Agonists
Not yet reported University of Maryland, Baltimore 63 participants Est. completion 2022-10-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05766358
Role Of Metabolic Adaptation In Weight Regain
Pennington Biomedical Research Center 27 participants Est. completion 2024-05-24 1 siteOther conditions: Weight Loss, Weight Gain, ObesityView official trial listing → -
Status unknown NCT NCT05779644
Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes Mellitus
Not yet reported RenJi Hospital 300 participants Est. completion 2025-02-23 1 siteType 2 diabetes Other conditions: Metformin, Obesity, Abdominal, Abdominal Fat, Non-Alcoholic Fatty Liver Disease, Metabolism Disorder, Glucose, Metabolism Disorder, LipidView official trial listing → -
Status unknown NCT NCT05782881
High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 16000 participants Est. completion 2024-12-31 107 sitesCardiovascular diseaseType 2 diabetes Other conditions: Coronary DiseaseView official trial listing → -
Completed NCT NCT05788965
Semaglutide in CFRD
Not yet reported, Not yet reported University of Minnesota 8 participants Est. completion 2024-12-31 1 siteOther conditions: Cystic Fibrosis, Cystic Fibrosis-related DiabetesView official trial listing → -
Completed NCT NCT05794581
A Study to Assess the Effects of CT-868 Treatment on Glucose Homeostasis in Participants with Type 1 Diabetes
Not yet reported Carmot Therapeutics, Inc. 32 participants Est. completion 2024-04-06 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05810597
A Research Study Looking at Similarity Between Tirzepatide Versions for Different Injection Devices
Not yet reported Eli Lilly and Company 65 participants Est. completion 2023-07-17 3 sitesOther conditions: HealthyView official trial listing → -
Completed NCT NCT05813795
A Phase 3 Study to Evaluate the Efficacy of XW003 in Adults With Overweight or Obesity
Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 664 participants Est. completion 2024-10-10 1 siteOther conditions: Weight ManagementView official trial listing → -
Status unknown NCT NCT05818995
Therapeutic Drug Use for CKD Patients
Qianfoshan Hospital 10000 participants Est. completion 2024-06-30 1 siteChronic kidney diseaseView official trial listing → -
Active, not recruiting NCT NCT05822544
Phase 1/1b Study of TLC-6740 in Healthy Subjects and Subjects With Obesity, With or Without Diabetes
Not yet reported OrsoBio, Inc 564 participants Est. completion 2027-01 4 sitesType 2 diabetes Other conditions: Healthy Subjects, ObesityView official trial listing → -
Completed NCT NCT05822830
A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities
Not yet reported Eli Lilly and Company 751 participants Est. completion 2024-11-13 32 sitesOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT05889637
Gastric Ultrasound Assessment for Preoperative Prandial State of Patients Taking Glucagon-Like Peptide-1 Receptor Agonists
The University of Texas Health Science Center, Houston 132 participants Est. completion 2023-07-12 1 siteOther conditions: Pulmonary AspirationView official trial listing → -
Completed NCT NCT05895643
Does Semaglutide Reduce Alcohol Intake in Patients With Alcohol Use Disorder and Comorbid Obesity?
Not yet reported Psychiatric Centre Rigshospitalet 108 participants Est. completion 2025-07-31 1 siteAlcohol use disorder Other conditions: Alcohol Abuse, Alcohol AddictionView official trial listing → -
Completed NCT NCT05920889
Glucagon-like Peptide 1 Receptor Agonist in Acute Large Vessel Occlusion Stroke Treated by Reperfusion Therapies
Not yet reported Chinese University of Hong Kong 140 participants Est. completion 2024-10-25 2 sitesCardiovascular disease Other conditions: Brain DiseasesView official trial listing → -
Status unknown NCT NCT05952882
Liraglutide and Metformin Combination on Weight Loss, Metabolic - Endocrine Parameters and Pregnancy Rate in Women With PCOS, Obesity and Infertility
Not yet reported Mỹ Đức Hospital 188 participants Est. completion 2025-12-31Other conditions: Polycystic Ovary Syndrome, Obesity, Infertility, FemaleView official trial listing → -
Terminated NCT NCT05960565
Glucagon Enhanced Insulin Absorption in Diabetes Mellitus Type 1
Not yet reported St. Olavs Hospital 9 participants Est. completion 2023-12-22 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05963022
A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes (SURPASS-CN-MONO)
Not yet reported Eli Lilly and Company 206 participants Est. completion 2024-10-09 28 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05965908
Effect of Liraglutide in Obese Women With Polycystic Ovary Syndrome
Not yet reported Beni-Suef University 183 participants Est. completion 2025-12-30 1 siteOther conditions: Polycystic OvaryView official trial listing → -
Status unknown NCT NCT05973799
Effect of Fasting on Hypoglycemic Counterregulation in Type 1 Diabetes
Not yet reported University of Cincinnati 10 participants Est. completion 2024-12-31 1 siteOther conditions: Hypoglycemia, Type1diabetesView official trial listing → -
Completed NCT NCT05978713
A Study of Tirzepatide (LY3298176) in Healthy Lactating Females
Not yet reported Eli Lilly and Company 11 participants Est. completion 2024-03-12 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT05990374
Therapeutic Effects and Effects on Body Fat of GLP-1 Receptor Agonists in Patients With Type 2 Diabetes for 1-4 Years
Not yet reported Nanjing First Hospital, Nanjing Medical University 100 participants Est. completion 2024-01-01 1 siteOther conditions: DiabetesView official trial listing → -
Active, not recruiting NCT NCT06005012
Semaglutide Treatment in the Real-world for Fibrosis Due to NAFLD in Obesity and T2DM
Not yet reported University of California, San Diego 120 participants Est. completion 2026-12-31 1 siteType 2 diabetes Other conditions: Fibrosis, Liver, Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Withdrawn NCT NCT06009653
Effects of Tirzepatide Plus Intensive Lifestyle Therapy on Body Weight and Metabolic Health in Latinos With Obesity
Not yet reported Washington University School of Medicine Est. completion 2024-05-29 1 siteOther conditions: Obesity, Metabolic DiseaseView official trial listing → -
Status unknown NCT NCT06014398
Improving Survivorship and Health-related Quality of Life in Patients With Primary Brain Tumours
Not yet reported Royal College of Surgeons, Ireland 50 participants Est. completion 2025-09-01 2 sitesOther conditions: Hypopituitarism, Radiotherapy-Induced Hypopituitarism, Brain TumorView official trial listing → -
Completed NCT NCT06017544
GLP-1RAs) and SGLT2is Combination Therapy and MACEs in Patients with Type 2 Diabetes.
University of Campania Luigi Vanvitelli 257 participants Est. completion 2024-12-01 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT06027567
The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial Pressure
Not yet reported Rigmor Højland Jensen 38 participants Est. completion 2025-10-28 2 sitesOther conditions: Idiopathic Intracranial Hypertension, Intracranial Pressure, Obesity, Pseudotumor Cerebri Syndrome, Papilledema, Weight LossView official trial listing → -
Active, not recruiting NCT NCT06037252
A Study of Investigational Tirzepatide (LY3298176) Doses in Participants With Type 2 Diabetes and Obesity
Not yet reported Eli Lilly and Company 414 participants Est. completion 2026-10 40 sitesType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT06038734
Using Point-of-Care-Ultrasound (POCUS) to Assess Gastric Contents Among Fasting Pre-operative Patients Taking GLP-1 Agonists.
University of North Carolina, Chapel Hill 108 participants Est. completion 2024-04-17 1 siteOther conditions: Delayed Gastric Emptying, GastroparesisView official trial listing → -
Completed NCT NCT06047548
A Study of LY3298176 (Tirzepatide) For the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
Not yet reported Eli Lilly and Company 441 participants Est. completion 2026-01-20 20 sitesOther conditions: Overweight, ObesityView official trial listing → -
Not yet recruiting NCT NCT06073184
Weight-loss Drug for Fertility-Sparing Treatment of Atypical Hyperplasia and Low-grade Cancer of the Endometrium
Not yet reported University Health Network, Toronto 71 participants Est. completion 2032-02Other conditions: Endometrial Cancer, Atypical HyperplasiaView official trial listing → -
Active, not recruiting NCT NCT06075667
A Study of Tirzepatide (LY3298176) Once Weekly in Adolescent Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
Not yet reported Eli Lilly and Company 160 participants Est. completion 2029-07 33 sitesOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT06082973
Dual-hormone Artificial Pancreas Versus Single-hormone Under Exercise and a Meal Challenge
Not yet reported Universitat Politècnica de València 15 participants Est. completion 2025-05-30 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT06099067
Harmonizing RCT-Duplicate Emulations In A Real World Replication Program (HARRP)
AstraZeneca 239990 participants Est. completion 2023-08-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06120556
Efficacy of Glucagon-like Peptide-1 Receptor Agonists According to Type 2 Diabetes Subtypes
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari 130 participants Est. completion 2023-10-31 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT06125873
Effect of Moringa Leaf Capsules on Glycemic Control of Type 2 Diabetic Patients
Not yet reported Islamabad Medical and Dental College 50 participants Est. completion 2024-08-01 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT06126354
Dexamethasone/Pancreatic Clamp P&F
Not yet reported Columbia University Est. completion 2026-03-31 1 siteOther conditions: Insulin Resistance, Prediabetic State, Non-Alcoholic Fatty Liver Disease, Overweight and ObesityView official trial listing → -
Completed NCT NCT06131437
A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight
Not yet reported Novo Nordisk A/S 809 participants Est. completion 2026-01-09 46 sitesOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT06154096
Liver Fat and Glucagon Resistance
Imperial College London 20 participants Est. completion 2024-09Other conditions: Steatosis of LiverView official trial listing → -
Active, not recruiting NCT NCT06162715
GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Pilot Trial
Not yet reported, Not yet reported Vanderbilt University Medical Center 30 participants Est. completion 2027-12-01 1 siteOther conditions: Severe Obesity, Obesity, BMI Greater Than 30View official trial listing → -
Suspended NCT NCT06171152
Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues
Not yet reported University of Chicago 30 participants Est. completion 2027-10-01 1 siteOther conditions: Multiple Sclerosis, Long COVID, Long Covid19, Obese, Obesity, Obesity, Morbid, Acute Leukemia in RemissionView official trial listing → -
Not yet recruiting NCT NCT06180616
Tirzepatide for the Treatment of Concurrent Type 1 Diabetes and Overweight or Obesity
Not yet reported Royal North Shore Hospital 40 participants Est. completion 2028-12Other conditions: Type 1 Diabetes Mellitus, Overweight and ObesityView official trial listing → -
Status unknown NCT NCT06182852
The Effect of GLP-1 Receptor Agonist on Bone Metabolism in Patients With Diabetes Mellitus
Nanjing First Hospital, Nanjing Medical University 330 participants Est. completion 2025-12-31 1 siteOther conditions: Diabete Type 2, Bone MetabolismView official trial listing → -
Completed NCT NCT06194955
The Effect of GIP, GLP-1 and GLP-2 in Individuals With Genetically Altered Receptor Function
Not yet reported University of Copenhagen 50 participants Est. completion 2026-04-01 1 siteOther conditions: Incretin EffectView official trial listing → -
Completed NCT NCT06201819
Liraglutide Effectiveness in Preoperative Weight-loss for Bariatric-metabolic Surgery
Not yet reported Hospital Civil Juan I. Menchaca 37 participants Est. completion 2023-05-01 1 siteOther conditions: Weight Loss, Bariatric Surgery Candidate, Obesity, MorbidView official trial listing → -
Status unknown NCT NCT06217848
The Effect of GLP-1 Agonist in Patients With Hypothalamic Obesity: Prospective, Pilot Study
Not yet reported Seoul National University Hospital 50 participants Est. completion 2024-03-08 1 siteOther conditions: Panhypopituitarism, Craniopharyngioma, Hypothalamic ObesityView official trial listing → -
Completed NCT NCT06221969
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Not yet reported Novo Nordisk A/S 1024 participants Est. completion 2026-04-06 197 sitesType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06234111
Semaglutide and Physical Activity for Obesity and Multimorbidity
Hvidovre University Hospital 35 participants Est. completion 2026-11 1 siteOther conditions: Obesity Morbid, Multimorbidity, ObesityView official trial listing → -
Completed NCT NCT06236672
Impact of GLP-1 RAs Compared to Basal Insulin Start in Patients Living With Type 2 Diabetes and Chronic Kidney Disease
LMC Diabetes & Endocrinology Ltd. 348 participants Est. completion 2023-11-29 1 siteType 2 diabetesChronic kidney diseaseView official trial listing → -
Active, not recruiting NCT NCT06240039
Direct Versus Indirect Effect of Amino Acids on Hepatokines
Not yet reported University of Copenhagen 30 participants Est. completion 2028-09-01 1 siteOther conditions: Non-Alcoholic Fatty Liver Disease, ObesityView official trial listing → -
Completed NCT NCT06272695
Glucagon Rescue of Insulin-Induced Hypoglycemia in Adults With Type 1 Diabetes Treated With Volagidemab
Not yet reported REMD Biotherapeutics, Inc. 24 participants Est. completion 2025-02-01 2 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Terminated NCT NCT06273163
Identifying Strategies to Curtail Weight Regain After GLP-1 Receptor Agonist Treatment Cessation
Not yet reported University of Texas Southwestern Medical Center 39 participants Est. completion 2025-08-05 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT06282458
Dose-Finding Study Evaluating Effect on Body Composition of Enobosarm in Patients Taking a GLP-1 for Chronic Weight Mgmt
Not yet reported Veru Inc. 168 participants Est. completion 2025-08-22 14 sites Stand-aloneOther conditions: Muscle Loss, ObesityView official trial listing → -
Completed NCT NCT06283641
Study to Evaluate the Safety and Effectiveness of Saxenda® for Weight Management in Routine Clinical Practice in Taiwan.
Novo Nordisk A/S 300 participants Est. completion 2025-01-13 15 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT06297616
A Study of LY3841136 in Japanese Participants With Obesity or Overweight
Not yet reported Eli Lilly and Company 128 participants Est. completion 2025-11-21 3 sitesOther conditions: Obesity, OverweightView official trial listing → -
Status unknown NCT NCT06301256
Evaluate the Efficacy of TIRZEPATIDE for the Treatment of Moderate to Severe HS Hidradenitis Suppurativa
Not yet reported Florida Academic Centers Research and Education, LLC 20 participants Est. completion 2025-03-11Other conditions: Hidradenitis SuppurativaView official trial listing → -
Completed NCT NCT06326060
A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Help People With Excess Body Weight Lose Weight
Not yet reported Novo Nordisk A/S 354 participants Est. completion 2025-05-01 70 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT06333496
Effect of a Glucagon Like Peptide 1 (GLP1) Booster in Healthy Humans
Not yet reported Alpine Biotech LLC 12 participants Est. completion 2024-05-08 1 siteOther conditions: Blood Sugar; High, Overweight and Obesity, Fat Burn, Obesity, Heart Health MarkersView official trial listing → -
Status unknown NCT NCT06344247
Comparison of the Efficacy and Safety of SGLT2i and GLP-1 Receptor Agonists in Obese Patients With Kidney Disease
Not yet reported RenJi Hospital 48 participants Est. completion 2025-12-01 1 siteChronic kidney disease Other conditions: ObesityView official trial listing → -
Completed NCT NCT06345066
A Study of LY3841136 in Overweight and Obese Participants
Not yet reported Eli Lilly and Company 96 participants Est. completion 2025-09-29 3 sitesOther conditions: Obesity, OverweightView official trial listing → -
Status unknown NCT NCT06346366
Glucose Control Through a Bihormonal Artificial Pancreas in Patients After Total Pancreatectomy
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 40 participants Est. completion 2024-04-01 1 site Stand-aloneOther conditions: Pancreatic Neoplasms, Type 3c Diabetes, Total PancreatectomyView official trial listing → -
Withdrawn NCT NCT06354101
The Purpose of This Registry Study is to Learn More About Metabolic Health: Approximately 15,000 Participants Who Are Overweight or Have Obesity With or Without Metabolic Diseases Are Expected to Participate in This Registry Study.
CorEvitas Est. completion 2023-07-01Other conditions: Metabolic HealthView official trial listing → -
Completed NCT NCT06370728
A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants
Not yet reported Eli Lilly and Company 30 participants Est. completion 2024-07-23 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT06373146
A Study of Tirzepatide (LY3298176) Plus Mibavademab Compared With Tirzepatide Alone in Adult Participants With Obesity
Not yet reported Eli Lilly and Company 392 participants Est. completion 2026-04-02 17 sitesOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT06388213
Investigation of the Evolution of Gastric Emptying by Gastric Ultra Sonography in Patients Treated With GLP-1 Receptor Agonists on a 7 Days Pausing Period.
University Hospital, Geneva 40 participants Est. completion 2026-05Type 2 diabetes Other conditions: Anesthesia, Pulmonary Aspiration of Gastric ContentsView official trial listing → -
Completed NCT NCT06408610
Moderate Continuous Versus High Interval Intensity Training on Gut Dysbiosis and GLP1 Hormone in IBS
Not yet reported Cairo University 66 participants Est. completion 2025-05-17 2 sitesOther conditions: Irritable Bowel Syndrome, Obesity, DysbiosisView official trial listing → -
Completed NCT NCT06410924
A Study to Evaluate DD01 in Overweight/Obese Subjects With MASLD/MASH
Not yet reported Neuraly, Inc. 67 participants Est. completion 2026-04-21 12 sitesMASLDMASHView official trial listing → -
Status unknown NCT NCT06438146
LIROH - Liraglutide for Obesity in HIV
Not yet reported Brigham and Women's Hospital 40 participants Est. completion 2025-05 1 siteOther conditions: Obesity, HIV InfectionsView official trial listing → -
Withdrawn NCT NCT06438874
Type 2 Diabetes Post Exercise Arterial Stiffness
Not yet reported University of Illinois at Chicago Est. completion 2024-12Type 2 diabetesView official trial listing → -
Completed NCT NCT06445075
Efficacy and Safety of Apitegromab for the Treatment of Adults Who Are Overweight or Obese
Not yet reported Scholar Rock, Inc. 102 participants Est. completion 2025-06-17 7 sitesOther conditions: Overweight and ObesityView official trial listing → -
Status unknown NCT NCT06449235
Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh
Not yet reported Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders 938 participants Est. completion 2025-06 1 siteOther conditions: Type2diabetesView official trial listing → -
Completed NCT NCT06481085
To Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 324 participants Est. completion 2025-06-30 31 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06485089
Effects of Tirzepatide on Blood, Imaging and Breast Tissue Biomarkers
University of Kansas Medical Center 25 participants Est. completion 2026-03-25 2 sitesOther conditions: Obesity, Breast Cancer RiskView official trial listing → -
Status unknown NCT NCT06498063
The Underlying Mechanisms Regarding the Effect of Glucagon on the Kidneys Will be Investigated in Healthy Males.
Not yet reported Ali Asmar 10 participants Est. completion 2025-07-31 1 siteOther conditions: Kidney DiseasesView official trial listing → -
Completed NCT NCT06500143
Residual Gastric Content After Holding of Glucagon-like Peptide-1 Receptor Agonists Before Elective Surgery
Ciusss de L'Est de l'Île de Montréal 94 participants Est. completion 2025-02-28 1 siteOther conditions: Gastric RetentionView official trial listing → -
Status unknown NCT NCT06500299
Evaluate the Safety and Efficacy of HDM1002 Tablets in Overweight and Obese Adults
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 180 participants Est. completion 2024-11-30Other conditions: Overweight and ObesityView official trial listing → -
Completed NCT NCT06500429
A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants Receiving a Glucagon-like Peptide-1 (GLP-1) Agonist
Not yet reported Neurogastrx, Inc. 120 participants Est. completion 2024-09-13 1 siteOther conditions: Overweight and Obesity, HealthyView official trial listing → -
Status unknown NCT NCT06501326
Efficacy and Safety of Liraglutide in the Treatment of Obesity Combined With Metabolism Associated Fatty Liver Disease
Not yet reported Affiliated Hospital of Nantong University 102 participants Est. completion 2025-02-28 1 siteOther conditions: Non-alcoholic Fatty Liver Disease, ObesityView official trial listing → -
Terminated NCT NCT06515418
Efficacy and Safety of Oral Azelaprag Plus Once Weekly Tirzepatide Compared with Tirzepatide Alone in Participants with Obesity Aged 55 Years and Over
Not yet reported BioAge Labs, Inc. 204 participants Est. completion 2025-02-12 14 sitesOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT06520540
HDM1002 Tablets in Chinese Overweight and Obese Adult Subjects
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 72 participants Est. completion 2024-12-30 1 siteOther conditions: Glucagon-Like Peptide-1 Receptor AgonistsView official trial listing → -
Completed NCT NCT06523101
A Study of PJ009 in Healthy Adult Volunteers
Not yet reported Chongqing Peg-Bio Biopharm Co., Ltd. 24 participants Est. completion 2023-05-15 1 siteOther conditions: Short Bowel SyndromeView official trial listing → -
Completed NCT NCT06533527
Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy
Not yet reported The Cleveland Clinic 69 participants Est. completion 2025-05-20 2 sitesType 2 diabetes Other conditions: Obesity, GastroparesisView official trial listing → -
Completed NCT NCT06534411
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both
Not yet reported Novo Nordisk A/S 1023 participants Est. completion 2026-07-09 163 sitesType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06546384
GLP-1 RA on Alcohol Consumption, Metabolism and Liver Parameters in Patients With Obesity and Fatty Liver Disease
Not yet reported Insel Gruppe AG, University Hospital Bern 64 participants Est. completion 2027-04-30 1 siteAlcohol use disorder Other conditions: Adiposity, Fatty LiverView official trial listing → -
Status unknown NCT NCT06555146
Semaglutide's Effect on Renal Hemodynamics and Function in Patients With Type 2 Diabetes Mellitus and Nephropathy
Not yet reported Bispebjerg Hospital 15 participants Est. completion 2025-03 1 siteType 2 diabetes Other conditions: Kidney Disease, ChronicView official trial listing → -
Not yet recruiting NCT NCT06558422
Human Models of Selective Insulin Resistance: Pancreatic Clamp
Not yet reported Columbia University 36 participants Est. completion 2029-02-28 1 siteMASLD Other conditions: Insulin Resistance, Hyperinsulinemia, Non-Alcoholic Fatty Liver Disease, Prediabetic State, ObesityView official trial listing → -
Status unknown NCT NCT06562088
A Drug-Drug Interaction (DDI) Study of HDM1002 With Rifampicin and Itraconazole in Healthy Subjects
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 40 participants Est. completion 2024-12-30 1 siteOther conditions: Healthy Adult SubjectView official trial listing → -
Completed NCT NCT06564753
Phase 2 Trials of NA-931 to Study Subjects Who Are Obese With at Least One Weight-related Comorbid Condition
Not yet reported Biomed Industries, Inc. 126 participants Est. completion 2025-04-18 5 sitesOther conditions: Weight Loss, Obesity, Body Weight, Body Weight ChangesView official trial listing → -
Active, not recruiting NCT NCT06565611
A Phase 2 Study Evaluating the Co-Administration of Bremelanotide With Tirzepatide for the Treatment of Obesity
Not yet reported Palatin Technologies, Inc 108 participants Est. completion 2025-03-31 4 sitesOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT06576401
A Study To Characterize Mass Balance Of [14C] HDM1002 in Chinese Healthy Subjects
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 10 participants Est. completion 2024-12 1 siteOther conditions: Healthy Adult SubjectView official trial listing → -
Status unknown NCT NCT06577584
Comparison of Diabetes Patients - Care Trajectory Versus Convention
Universitaire Ziekenhuizen KU Leuven 20000 participants Est. completion 2025-12Type 2 diabetesView official trial listing → -
Enrolling by invitation NCT NCT06581120
GLP_1 RA Ultrasound Study
Children's Hospital Medical Center, Cincinnati 100 participants Est. completion 2026-07 1 siteOther conditions: Glucagon Like Peptide-1 (GLP-1, Delayed Gastric Emptying, Risk of Aspiration, Diabetes, Morbid ObesityView official trial listing → -
Completed NCT NCT06588283
Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Moderate-to-Severe Plaque Psoriasis and Obesity or Overweight
Not yet reported Eli Lilly and Company 281 participants Est. completion 2026-06-01 72 sitesOther conditions: Psoriasis, ObesityView official trial listing → -
Completed NCT NCT06588296
Ixekizumab Concomitantly Administered With Tirzepatide in Adults With Psoriatic Arthritis and Obesity or Overweight
Not yet reported Eli Lilly and Company 279 participants Est. completion 2026-04-23 86 sitesOther conditions: Psoriatic Arthritis, ObesityView official trial listing → -
Completed NCT NCT06588504
Research Study in Japan to Compare Dasiglucagon With Glucagon in Treating Very Low Levels of Blood Sugar in Asian Adults With Type 1 Diabetes and Testing of Dasiglucagon for the Same Condition in Japanese Adolescents
Not yet reported Novo Nordisk A/S 38 participants Est. completion 2025-07-20 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT06601517
A Drug-Drug Interaction (DDI) Study of HDM1002 With Repaglinide, Atorvastatin, Digoxin and Rosuvastatin in Healthy Subjects and Overweight Subjects.
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 30 participants Est. completion 2025-04 1 siteOther conditions: Healthy Adult Subject, Overweight SubjectView official trial listing → -
Completed NCT NCT06603571
A Study to Investigate Weight Management With LY3841136 and Tirzepatide (LY3298176), Alone or in Combination, in Adult Participants With Obesity or Overweight With Type 2 Diabetes
Not yet reported Eli Lilly and Company 367 participants Est. completion 2026-09-14 52 sitesOther conditions: Obesity, OverweightView official trial listing → -
Status unknown NCT NCT06608329
A Relative Bioavailability and Food Effect Study of HDM1002 in Healthy Subjects
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 33 participants Est. completion 2024-12 1 siteOther conditions: Healthy Adult SubjectView official trial listing → -
Completed NCT NCT06608433
Glucagon-like Peptide-1 Receptor Agnoists for the Assessment of Adrenal Function
Not yet reported University Hospital, Basel, Switzerland 22 participants Est. completion 2025-11-30 1 siteOther conditions: Healthy Volunteer Study, HPA, Cortisol Deficiency, Adrenal InsufficiencyView official trial listing → -
Completed NCT NCT06621017
Effect of GLP-1 Analogue ROSE-010 on Appetite in Overweight and Obese Subjects
Not yet reported Rose Pharma Inc 40 participants Est. completion 2025-02-27 1 siteOther conditions: Obesity; OverweightView official trial listing → -
Completed NCT NCT06634927
Pharmacokinetic Similarity, Safety, and Immunogenicity of Semaglutide Injection and Ozempic ® Injection in Healthy Subjects.
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 68 participants Est. completion 2025-02-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06635057
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes During Ramadan
Not yet reported Eli Lilly and Company 166 participants Est. completion 2026-04-15 29 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06640972
Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists
Not yet reported Response Pharmaceuticals 68 participants Est. completion 2025-05-13 1 siteOther conditions: Triglycerides, Weight Gain Trajectory, Cholesterol, ElevatedView official trial listing → -
Active, not recruiting NCT NCT06643728
A Study to Investigate Weight Management With Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Adults With Obesity or Overweight
Not yet reported Eli Lilly and Company 252 participants Est. completion 2027-01 12 sitesOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT06648031
Comparison of the Safety, Efficacy and Pharmacokinetics of DehydraTECH -CBD and DehydraTECH-GLP1 Agonists Alone or in Combination, in Overweight or Obese, Pre- and Type 2 Diabetic Participants
Not yet reported Lexaria Bioscience Corp. 148 participants Est. completion 2025-07-31 7 sitesOther conditions: Type2diabetesView official trial listing → -
Completed NCT NCT06660134
Strict Weight Management Based on GLP-1 RA for Ablation Outcomes in Overweight or Obese Patients with T2DM and AF
Not yet reported Shanghai Chest Hospital 174 participants Est. completion 2024-01-10 1 siteType 2 diabetes Other conditions: Atrial Fibrillation (AF)View official trial listing → -
Active, not recruiting NCT NCT06662383
A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity
Not yet reported Eli Lilly and Company 800 participants Est. completion 2026-12 65 sitesOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT06671340
Chronic Dorzagliatin on Insulin and Incretin Function in Intermediate Hyperglycemia and Type 2 Diabetes
Not yet reported Elaine Chow 30 participants Est. completion 2026-01-31 1 siteType 2 diabetesPrediabetes Other conditions: Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT06682351
Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention
Not yet reported Stanford University 200 participants Est. completion 2027-12 1 siteType 2 diabetesPrediabetesView official trial listing → -
Completed NCT NCT06685146
The Glucose-Independent Effects of Exogenous Glucagon on Insulin Secretion and Cognitive Function in Healthy Subjects
Not yet reported Nicolai Jacob Wewer Albrechtsen 15 participants Est. completion 2025-07-21 1 siteOther conditions: Glucose Metabolism, Insulin SecretionView official trial listing → -
Completed NCT NCT06721910
Interplay Between Interleukin-6 and Glucagon in the Regulation of Human Amino Acid and Protein Homeostasis
Not yet reported University Hospital, Basel, Switzerland 26 participants Est. completion 2025-09-18 1 siteOther conditions: Healthy, Glucagon Resistance, Amino Acid ChangeView official trial listing → -
Completed NCT NCT06722326
Hydrogen-rich Water and Appetite in Obesity
Not yet reported University of Novi Sad, Faculty of Sport and Physical Education 36 participants Est. completion 2024-12-30 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT06722560
SHORT-term Effects of GLucagon-like Peptide One on BonE
Not yet reported Odense University Hospital 12 participants Est. completion 2025-10-31 1 siteOther conditions: To Investigate the Physiological Effect of GLP-1 on the Skeleton, Healthy VolunteerView official trial listing → -
Not yet recruiting NCT NCT06732245
Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese
Not yet reported Biomed Industries, Inc. 224 participants Est. completion 2027-12-15 17 sitesOther conditions: Obesity and OverweightView official trial listing → -
Active, not recruiting NCT NCT06734273
Randomized Control Trial of Sleeve Gastrectomy With Tirzepatide in Maximizing Weight Loss
Not yet reported Nicholas Skertich 42 participants Est. completion 2028-09 1 siteOther conditions: Obesity and Obesity-related Medical ConditionsView official trial listing → -
Completed NCT NCT06737042
Efficacy and Safety of GZR18 Every 2 Weeks Versus Tirzepatide and Placebo in Obese or Overweight Participants
Not yet reported Gan and Lee Pharmaceuticals, USA 326 participants Est. completion 2026-02-27 20 sitesOther conditions: Obesity and OverweightView official trial listing → -
Completed NCT NCT06738979
A Clinical Study Comparing Semaglutide Injection and Wegovy® for Weight Management in Obese Subjects
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 408 participants Est. completion 2026-05-26 66 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT06739044
Efficacy and Safety of Semaglutide Injection vs Ozempic® in Patients With Type 2 Diabetes
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 494 participants Est. completion 2025-02-21 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06745128
Tirzepatide for Obesity and Meth Use Disorder
Not yet reported University of Texas Southwestern Medical Center 35 participants Est. completion 2026-02-12 1 siteOther conditions: Obesity, Methamphetamine Use DisorderView official trial listing → -
Active, not recruiting NCT NCT06747468
Avexitide for Treatment of Post-Bariatric Hypoglycemia
Not yet reported Amylyx Pharmaceuticals Inc. 75 participants Est. completion 2027-02 21 sitesOther conditions: Post Bariatric HypoglycemiaView official trial listing → -
Completed NCT NCT06752967
Hormonal Control of Energy and Macronutrient Intake in Obesity (MEMORY)
Not yet reported Steno Diabetes Center Copenhagen 47 participants Est. completion 2026-06-25 1 siteOther conditions: Obesity, Normal Weight, OverweightView official trial listing → -
Withdrawn NCT NCT06759740
An Exploratory Study of 68Ga-DOTA-SEMA in Preoperative Precise Imaging of Patients with Glucagon-Like Peptide-1 Receptor (GLP1R) Positive Insulinomas
Not yet reported The Affiliated Hospital Of Southwest Medical University Est. completion 2026-12 1 siteOther conditions: HypoglycaemiaView official trial listing → -
Completed NCT NCT06762314
Efficacy and Safety of Empagliflozin or Semaglutide in Overweight/Obese Patients With Type 1 Diabetes
Not yet reported Mostafa Bahaa 114 participants Est. completion 2026-01-20 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT06774807
Blocking of the Gut Hormone Receptor for Glucagon-like Peptide 2 (GLP-2) by the GLP-2 Receptor Antagonist GLP-2(3-33)
Not yet reported University of Copenhagen 10 participants Est. completion 2024-09-07 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT06779929
Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes
Brigham and Women's Hospital 70000 participants Est. completion 2026-03-01 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06788626
Glucagon-like Peptide 1 Receptor Agonist in Acute Large Vessel Occlusion Stroke After Endovascular Treatment
Not yet reported Wei Hu 390 participants Est. completion 2028-02 1 siteCardiovascular disease Other conditions: Large Vessel Occlusion, Neuroprotective Drugs, Endovascular TreatmentView official trial listing → -
Active, not recruiting NCT NCT06801015
Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor Functions
Not yet reported Mayo Clinic 30 participants Est. completion 2028-03-31 1 siteOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT06803888
Bariatric Surgery vs. Semaglutide vs. Tirzepatide
Not yet reported Ali Aminian 140 participants Est. completion 2027-12-01 1 siteOther conditions: Obesity and Obesity-related Medical ConditionsView official trial listing → -
Active, not recruiting NCT NCT06807970
Optimization of Obesity for Total Knee Replacement With Glucagon-like Peptide-1 Receptor Agonist
Not yet reported The University of Hong Kong 54 participants Est. completion 2028-07-01 1 siteOsteoarthritisView official trial listing → -
Completed NCT NCT06818292
Investigation of the Relationship Between Peripheral and Central Metabolic Changes Induced by GLP-1 Agonists
Not yet reported Nils Opel 10 participants Est. completion 2024-12-06 1 siteOther conditions: HealthyView official trial listing → -
Active, not recruiting NCT NCT06854614
Sequential Therapy Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)
Not yet reported The Cleveland Clinic 150 participants Est. completion 2028-04-28 1 siteOther conditions: ObesityView official trial listing → -
Suspended NCT NCT06854861
Premixed Glucagon/Insulin Solution for Faster Insulin Absorption in Type 1 Diabetes
Not yet reported, Not yet reported St. Olavs Hospital 30 participants Est. completion 2025-12-31 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT06854952
A Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of TERN-601 in Adults With Overweight or Obesity
Not yet reported Terns, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 167 participants Est. completion 2025-09-19 17 sitesOther conditions: Overweight or ObesityView official trial listing → -
Active, not recruiting NCT NCT06861439
GLP-1s to Enhance Lasting Optimal Weight
Not yet reported Wake Forest University Health Sciences 40 participants Est. completion 2026-12-31 1 siteOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT06864026
A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)
Not yet reported Eli Lilly and Company 200 participants Est. completion 2027-08 55 sitesOther conditions: Psoriatic Arthritis, Overweight or ObesityView official trial listing → -
Not yet recruiting NCT NCT06872060
The Effects of Glucagon on Renal Regional Blood Flow in Humans Measured by Magnetic Resonance.
Not yet reported Bispebjerg Hospital 10 participants Est. completion 2027-11-01Other conditions: Kidney DiseasesView official trial listing → -
Active, not recruiting NCT NCT06877208
The Effect of Glucagon on Cerebral Glucose Metabolism in Healthy Humans
Not yet reported Nicolai Jacob Wewer Albrechtsen 12 participants Est. completion 2027-08 1 siteOther conditions: Cerebral Glucose MetabolismView official trial listing → -
Completed NCT NCT06890611
A Study of Bimagrumab Alone (LY3985863) and Bimagrumab With Tirzepatide (LY900042) in Healthy Participants
Not yet reported Eli Lilly and Company 125 participants Est. completion 2025-09-26 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT06893211
Effect of Tirzepatide on Brown Adipose Tissue in Obesity
Not yet reported University Medical Centre Ljubljana 34 participants Est. completion 2025-12-20 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT06895408
Separate and Combined Extrapancreatic Effects of GIP and GLP-1
Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2025-07-14 1 siteOther conditions: Pancreatectomy; HyperglycemiaView official trial listing → -
Withdrawn NCT NCT06901349
A Study of Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Participants With Obesity or Overweight With Type 2 Diabetes
Not yet reported Eli Lilly and Company Est. completion 2025-06-10 50 sitesOther conditions: Obesity, OverweightView official trial listing → -
Enrolling by invitation NCT NCT06904846
To Evaluate the Change in Glucose Parameters in Adult Patients With Type 1 or Type 2 Diabetes From Europe Using the iCan o3 CGM System for 60 Days Period
Not yet reported Sinocare 70 participants Est. completion 2026-06-30 1 siteOther conditions: Diabetes Mellitus, Continuous Glucose Monitoring SystemView official trial listing → -
Completed NCT NCT06913881
Comparative Cardiovascular Effectiveness of GLP-1 RAs vs. Insulin in Early-Onset Type 2 Diabetes
Karolinska Institutet 92100 participants Est. completion 2025-01-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06914141
Comparative Effectiveness of Tirzepatide Versus Semaglutide in Individuals With Heart Failure With Preserved Ejection Fraction
Brigham and Women's Hospital 28118 participants Est. completion 2025-06-01 1 siteType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT06914154
Emulation of the SUMMIT Heart Failure Trial in Healthcare Claims Data
Brigham and Women's Hospital 11265 participants Est. completion 2025-06-01 1 siteType 2 diabetesHeart failureView official trial listing → -
Active, not recruiting NCT NCT06914895
A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight
Not yet reported Eli Lilly and Company 905 participants Est. completion 2026-12 146 sitesOther conditions: Type 1 Diabetes, Obesity, OverweightView official trial listing → -
Completed NCT NCT06916065
A Study of Eloralintide (LY3841136) and Eloralintide With Tirzepatide in Participants With Overweight or Obesity
Not yet reported Eli Lilly and Company 188 participants Est. completion 2026-01-19 3 sitesOther conditions: Overweight, ObesityView official trial listing → -
Active, not recruiting NCT NCT06918405
Efficacy and Safety of Tirzepatide for Weight Management
Not yet reported Chittagong Medical College 440 participants Est. completion 2026-06-30 1 siteOther conditions: Obesity and Obesity-related Medical ConditionsView official trial listing → -
Completed NCT NCT06921824
Investigating the Acute Effects of Increasing Glucagon Exposure in Healthy Participants
Not yet reported Nicolai Jacob Wewer Albrechtsen 16 participants Est. completion 2025-09-19 1 siteOther conditions: Glucose Metabolism, GlucagonView official trial listing → -
Enrolling by invitation NCT NCT06924697
Effect of Glucagon-like Peptide-1 (GLP-1) Receptor Agonist Stimulation on Smoking Consumption in Type 2 Diabetes Patients
Not yet reported Shanghai East Hospital 46 participants Est. completion 2026-07-01 1 siteType 2 diabetes Other conditions: Nicotine Dependence, CigarettesView official trial listing → -
Completed NCT NCT06935838
Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV
Not yet reported University of Hawaii 12 participants Est. completion 2026-06-02 1 siteOther conditions: Obesity and Overweight, HIV, Chronic InflammationView official trial listing → -
Not yet recruiting NCT NCT06955130
Lactate and Glycerol Contribution to Gluconeogenesis
Not yet reported Rutgers, The State University of New Jersey 48 participants Est. completion 2030-04-30Type 2 diabetes Other conditions: Obesity, HealthyView official trial listing → -
Active, not recruiting NCT NCT06962280
A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight
Not yet reported Eli Lilly and Company 465 participants Est. completion 2027-07 79 sitesOther conditions: Type 1 Diabetes, Obesity, OverweightView official trial listing → -
Active, not recruiting NCT NCT06965413
A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity
Not yet reported Hoffmann-La Roche 285 participants Est. completion 2027-03-31 35 sitesOther conditions: Obesity, Overweight, Overweight With One Weight Related ComorbidityView official trial listing → -
Active, not recruiting NCT NCT06980623
Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction
Brigham and Women's Hospital 26000 participants Est. completion 2026-10-01 1 siteType 2 diabetesHeart failureView official trial listing → -
Withdrawn NCT NCT06982378
GLP-1 RA on Liver OMICS in MASLD
Medical College of Wisconsin Est. completion 2026-07-09 1 siteMASLD Other conditions: Diabetes, ObesityView official trial listing → -
Active, not recruiting NCT NCT06986603
Glucagon Dose-Response in Patients With Post-Bariatric Hypoglycemia
Not yet reported Joslin Diabetes Center 28 participants Est. completion 2026-09-01 2 sitesOther conditions: Hypoglycemia, Hypoglycemia, Reactive, Bariatric SurgeryView official trial listing → -
Active, not recruiting NCT NCT07000955
Tolerance and Pharmacokinetic/Pharmacokinetic Study of IBI362 15mg in Patients With Moderate to Severe Obesity
Not yet reported, Not yet reported Innovent Biologics (Suzhou) Co. Ltd. 98 participants Est. completion 2027-05-14 1 siteOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07021937
Brain Plasticity and GLP-1 Receptor Agonist Treatment for Obesity
Not yet reported University of Colorado, Denver 120 participants Est. completion 2031-04-30 1 siteOther conditions: Obesity/TherapyView official trial listing → -
Not yet recruiting NCT NCT07030621
Efficacy of Semaglutide in Improving Neurological Outcomes After Endovascular Thrombectomy for Acute Ischemic Stroke: A Randomized Double-Blind Controlled Trial
Not yet reported RenJi Hospital 436 participants Est. completion 2028-01-31 1 siteCardiovascular diseaseView official trial listing → -
Enrolling by invitation NCT NCT07057310
Aging Well: Targeting Obesity With GLP-1 Agonists to Enhance Physical and Vascular Health in Postmenopausal Women
Not yet reported Mayo Clinic 30 participants Est. completion 2027-03-31 1 siteOther conditions: Obesity, MenopauseView official trial listing → -
Not yet recruiting NCT NCT07073053
The Role of Glucagon-Like Peptide-1 Receptor Agonists in Coronary Artery Diseases and Their Potential Mechanisms
Not yet reported Taipei Veterans General Hospital, Taiwan 60 participants Est. completion 2028-07-31 1 siteType 2 diabetes Other conditions: Glucagon-Like Peptide-1 Receptor Agonists, Coronary Arterial Disease (CAD)View official trial listing → -
Active, not recruiting NCT NCT07073417
A Study to Compare XW003 Injection and Semaglutide Injection in Chinese Adults With Obesity (SLIMMER-UP-SWITCH)
Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 163 participants Est. completion 2027-08-23 1 siteOther conditions: Obesity, Weight ManagementView official trial listing → -
Not yet recruiting NCT NCT07078838
Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer
Not yet reported UNC Lineberger Comprehensive Cancer Center 40 participants Est. completion 2029-03 1 siteOther conditions: Endometrial Cancer, Endometrial Intraepithelial Neoplasia, Grade 1 Endometrial Endometrioid CarcinomaView official trial listing → -
Completed NCT NCT07088718
Prediction of the SURPASS-CVOT Cardiovascular Outcome Trial in Healthcare Claims Data
Brigham and Women's Hospital 44671 participants Est. completion 2025-07-30 1 siteType 2 diabetes Other conditions: Major Adverse Cardiac Events, Cardiovascular (CV) RiskView official trial listing → -
Enrolling by invitation NCT NCT07092605
Effectiveness of Microdosed GLP-1 in Improving Health, Quality of Life, and Longevity Measures
Not yet reported AgelessRx 150 participants Est. completion 2025-12-01 1 siteOther conditions: Longevity, Quality of Life, Mood, Inflammation, Immune Health, Pain Management, Weight Management, AlertnessView official trial listing → -
Completed NCT NCT07096063
Comparative Effectiveness of Tirzepatide and Semaglutide in Individuals at Cardiovascular Risk
Brigham and Women's Hospital 887132 participants Est. completion 2025-07-15 1 siteType 2 diabetes Other conditions: Overweight, Cardiovascular (CV) RiskView official trial listing → -
Withdrawn NCT NCT07097974
Evaluation of the Efficacy of the Composite WM Formula in Body Weight Change
Not yet reported TCI Co., Ltd. Est. completion 2025-12-30 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT07097987
Evaluation of the Efficacy of the Composite WM Formula in Promoting GLP-1 Secretion
Not yet reported TCI Co., Ltd. 20 participants Est. completion 2026-04-24 1 siteOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07099742
Effectiveness and Safety of Tirzepatide Among Participants With Obesity With or Without Type 2 Diabetes Mellitus (T2DM)
Dr. Md. Alimur Reza 364 participants Est. completion 2026-07 3 sitesOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07100691
Gastric Emptying With Metoclopramide in GLP-1 Agonist Patients Undergoing Elective Surgery
Not yet reported Mater Misericordiae University Hospital 80 participants Est. completion 2026-06 2 sitesOther conditions: Pulmonary Aspiration During Anaesthetic Induction, Gastric Emptying Time, Preoperative Risk Assessment, Obesity (Disorder)View official trial listing → -
Active, not recruiting NCT NCT07115069
Comparison of Body Composition Changes With Weight Loss Interventions
Vanderbilt University Medical Center 60 participants Est. completion 2027-12 1 siteOther conditions: ObesityView official trial listing → -
Enrolling by invitation NCT NCT07117240
Evaluation of the Efficacy and Safety of GLP-1 Receptor Agonist Therapy In Steroid-Induced Diabetes
Not yet reported Medical University of Warsaw 100 participants Est. completion 2028-07-10 1 siteOther conditions: Steroid-Induced Diabetes, Steroid-Induced Hyperglycemia, DiabetesView official trial listing → -
Active, not recruiting NCT NCT07128082
The Long COVID Treatment Trial
Not yet reported Scripps Translational Science Institute 1000 participants Est. completion 2026-12 1 siteOther conditions: Long COVIDView official trial listing → -
Not yet recruiting NCT NCT07140055
A Research Study to Evaluate BLX-7006 in Healthy Adults
Not yet reported Biolexis Therapeutics 76 participants Est. completion 2026-05 1 siteOther conditions: Normal Healthy Volunteer, Safety After Oral IntakeView official trial listing → -
Enrolling by invitation NCT NCT07140289
Effect of Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA) on Gastric Emptying
Wael Saasouh, MD 100 participants Est. completion 2028-06-01 1 siteOther conditions: Gastric Emptying, Glucagon-Like Peptide-1 Receptor Agonists, Intermittent Fasting, Intraoperative Complication Due to Anesthesia, Respiratory Aspiration of Gastric ContentsView official trial listing → -
Completed NCT NCT07141472
Glucagon Like Peptide 1 (GLP-1) Booster™ RCT Study
Not yet reported Lawry Han 69 participants Est. completion 2025-08-14 1 siteOther conditions: Blood Sugar; High, Overweight and Obesity, Fat Loss, GLP-1, GlucagonView official trial listing → -
Completed NCT NCT07143227
A Study of XW003 Injection in Chinese Adolescents With Obesity
Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 48 participants Est. completion 2026-04-18 1 siteOther conditions: Obese Adolescents, ObesityView official trial listing → -
Completed NCT NCT07158385
Effect of High Fat High Protein Meal in Type 1 Diabetes
Not yet reported Cumhuriyet University 11 participants Est. completion 2021-02-17 1 siteOther conditions: Type 1 Diabetes Mellitus, AdolescentView official trial listing → -
Not yet recruiting NCT NCT07176663
Efficacy and Safety of Tirzepatide (Spartina) in Chronic Kidney Failure
Not yet reported Shahid Beheshti University of Medical Sciences 15 participants Est. completion 2026-05-01 1 siteOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07179120
Can Fat-Burning Shots Boost Fertility? Comparing Weight-Loss Injections vs. Healthy Habits for Obese Men With Low Sperm Health
Not yet reported First Affiliated Hospital of Wenzhou Medical University 180 participants Est. completion 2027-01-02Other conditions: Obesity-related Male InfertilityView official trial listing → -
Not yet recruiting NCT NCT07216352
Evaluate the Safety and Efficacy of a Topical Serum (AGE Serum) in Improving Visible Signs of Aging
Not yet reported Goldman, Butterwick, Fitzpatrick and Groff 25 participants Est. completion 2026-05-30 1 site Added to GLP-1Other conditions: Laxity; SkinView official trial listing → -
Not yet recruiting NCT NCT07217743
Assess Impact of Poly-L-lactic Acid on GLP1 Subjects
Not yet reported Goldman, Butterwick, Fitzpatrick and Groff 20 participants Est. completion 2026-10-31 1 site Added to GLP-1Other conditions: Laxity; SkinView official trial listing → -
Not yet recruiting NCT NCT07221461
Assess Impact of Microdroplet Hyaluronic Acid Filler on Skin Quality in Patients on Glucagon-like Peptide-1 Agonists
Not yet reported Goldman, Butterwick, Fitzpatrick and Groff 24 participants Est. completion 2026-03-02 1 site Added to GLP-1Other conditions: WrinkleView official trial listing → -
Active, not recruiting NCT NCT07225829
A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis
Not yet reported 4Moving Biotech 129 participants Est. completion 2026-10-28 22 sitesOsteoarthritis Other conditions: Synovitis of KneeView official trial listing → -
Completed NCT NCT07240246
Effect of a Dietary Supplement on Hormones Involved in Appetite Regulation in Overweight and Obese Adults
Not yet reported FFoQSI - Austrian Competence Centre for Feed and Food Quality, Safety & Innovation 40 participants Est. completion 2026-05-12 1 siteOther conditions: GLP-1, Obesity &Amp; Overweight, Dietary SupplementView official trial listing → -
Not yet recruiting NCT NCT07249554
Combination Therapy for Alcohol Use Disorder
Not yet reported Johns Hopkins University 45 participants Est. completion 2028-09 1 siteAlcohol use disorderView official trial listing → -
Not yet recruiting NCT NCT07251556
GLP-1 Receptor Agonists in Non-diabetic Patients With Psoriatic Arthritis
Not yet reported Chinese University of Hong Kong 40 participants Est. completion 2027-01-01Other conditions: Psoriasis ArthritisView official trial listing → -
Terminated NCT NCT07254988
Gut Peptides and Bone Remodeling in Children With Neuromuscular Disorders
Not yet reported University of Copenhagen 3 participants Est. completion 2025-12-01 1 siteOther conditions: Spinal Muscular Atrophy (SMA), Cerebral Palsy (CP), Duchenne Muscular Dystrophy (DMD)View official trial listing → -
Not yet recruiting NCT NCT07265752
Tirzepatide for the Treatment of Cannabis Use Disorder
Not yet reported Brigham and Women's Hospital 6 participants Est. completion 2028-06-30Other conditions: Cannabis Use DisorderView official trial listing → -
Not yet recruiting NCT NCT07276763
Impact of Discontinuing GLP-1 Receptor Agonists for Two Weeks Prior to Upper Endoscopy on the Risk of Gastric Retention
Fudan University 16509 participants Est. completion 2025-12-15 1 siteOther conditions: Gastric RetentionView official trial listing → -
Completed NCT NCT07281937
A Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
Not yet reported Verdiva Bio Dev Limited 206 participants Est. completion 2026-07-23 22 sitesOther conditions: Obesity, OverweightView official trial listing → -
Not yet recruiting NCT NCT07292519
Tirzepatide Combined With Cognitive-Behavioural Therapy (CBT) for Adults With Alcohol Use Disorder (AUD) and Overweight/Obesity (OOB)
Not yet reported South West Sydney Local Health District 46 participants Est. completion 2028-01-15 1 siteAlcohol use disorder Other conditions: Overweight or Obese, Comorbidities and Coexisting ConditionsView official trial listing → -
Completed NCT NCT07294898
A Study to Investigate the Effect of a Low-fat Meal and Evening Dosing on KAI-7535 in Participants Living With Obesity or Overweight
Not yet reported Kailera 18 participants Est. completion 2026-01-26 1 siteOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT07297238
Effect of GLP-1 on Intestinal Barrier Function in SBS-IF Patients: A Preliminary Exploration.
Not yet reported Jinling Hospital, China 20 participants Est. completion 2026-06-30 2 sitesOther conditions: Short Bowel Syndrome (SBS), Intestinal FailureView official trial listing → -
Not yet recruiting NCT NCT07298915
The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED)
Not yet reported University of Virginia 24 participants Est. completion 2027-06 1 siteOther conditions: Obesity & OverweightView official trial listing → -
Active, not recruiting NCT NCT07299084
A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 40 participants Est. completion 2026-11 1 siteType 2 diabetes Other conditions: Overweight, ObesityView official trial listing → -
Not yet recruiting NCT NCT07300982
Studies of Insulin and Glucagon Action in the Liver
Not yet reported, Not yet reported Duke University 40 participants Est. completion 2029-12 1 siteOther conditions: Diabetes (DM)View official trial listing → -
Active, not recruiting NCT NCT07303556
Improving Cardiovascular Disease Diagnosis and Treatment in Kazakhstan Using Metabolic Correction With GLP-1 Drugs
Not yet reported Nazarbayev University 120 participants Est. completion 2026-11-01 1 siteHeart failure Other conditions: Diabete Type 2, Arterial HypertensionView official trial listing → -
Completed NCT NCT07304141
Pharmacological Treatment - An Overview of Its Role in Managing Childhood Obesity
Göteborg University 128 participants Est. completion 2025-12-12 1 siteOther conditions: Obesity (Disorder), Child ObesityView official trial listing → -
Enrolling by invitation NCT NCT07319286
Role of Glucagon-like Peptide-1 Receptor Agonists in Menstrual Irregularities in Adolescent Females With Type 1 Diabetes Mellitus
Not yet reported, Not yet reported Ain Shams University 50 participants Est. completion 2027-03 2 sitesOther conditions: Menstrual Irregularities, Type1 Diabetes Mellitus, Glucagon-Like Peptide-1 Receptor Agonists, Female Reproductive HealthView official trial listing → -
Not yet recruiting NCT NCT07319975
Effect of Semaglutide and Tirzepatide Combined With Exercise in Obesity
Not yet reported Istanbul Galata University 48 participants Est. completion 2026-12 1 siteOther conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT07325435
Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor Agonists
Not yet reported MaryAnn Banerji 60 participants Est. completion 2028-06-30 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07349641
A Study of Weight Loss Intervention With Tirzepatide and Progestin Intrauterine Device to Treat Endometrial Hyperplasia and Grade 1 Endometrial Cancer
Not yet reported National Cancer Institute (NCI) 55 participants Est. completion 2030-10-31 3 sitesOther conditions: Endometrial Atypical Hyperplasia/Endometrioid Intraepithelial Neoplasia, FIGO Grade 1 Endometrial Endometrioid AdenocarcinomaView official trial listing → -
Not yet recruiting NCT NCT07350512
Investigating the Acute Effects of Increasing Alanine Exposure in Healthy Participants
Not yet reported Nicolai Jacob Wewer Albrechtsen 15 participants Est. completion 2027-01-20 1 siteOther conditions: Glucose Metabolism, GlucagonView official trial listing → -
Completed NCT NCT07360262
Gastric Emptying Recovery After GLP-1 RA Cessation
Wonkwang University Hospital 186 participants Est. completion 2026-01-12 2 sitesOther conditions: Gastric Emptying, Gastroparesis, Preoperative CareView official trial listing → -
Not yet recruiting NCT NCT07360457
GLP1 Analogues and the Risk of Osteoarthritis
Beni-Suef University 390 participants Est. completion 2027-03-01OsteoarthritisView official trial listing → -
Active, not recruiting NCT NCT07366710
Measuring Amino Acid and Glucose Metabolism in Healthy Volunteers and NAFLD Patients Using Total-body PET
Not yet reported Copenhagen University Hospital, Rigshospitalet 36 participants Est. completion 2027-10 1 siteMASLD Other conditions: Glucose MetabolismView official trial listing → -
Completed NCT NCT07368855
GLP-1 Medicines and Mental Health Changes
Not yet reported University of California, San Diego 90 participants Est. completion 2025-07-01 1 siteOther conditions: Obesity, Depression, GLP-1View official trial listing → -
Completed NCT NCT07370922
Glucagon-Like Peptide 1 Receptor Agonist in Diabetes Mellitus Management in Children and Adolescents With Transfusion-Dependent Thalassemia
Not yet reported Ain Shams University 80 participants Est. completion 2026-01-05 1 siteOther conditions: Transfusion Dependent Beta ThalassemiaView official trial listing → -
Completed NCT NCT07373236
The Effect of Endogenous GLP-1 on Glucagon Secretion in Type 1 Diabetes
Not yet reported Asger Lund, MD 12 participants Est. completion 2026-04-09 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT07374445
Research on Timing of Liraglutide Therapy in Patients With Obesity After Metabolic Surgery
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 100 participants Est. completion 2025-06-01 1 siteOther conditions: Obesity, Weight Loss, Bariatric SurgeryView official trial listing → -
Not yet recruiting NCT NCT07382024
Tirzepatide to Reduce rEcurrence And Burden After Ablation of Atrial Fibrillation
Not yet reported National Taiwan University Hospital 200 participants Est. completion 2028-07-31 1 siteOther conditions: Atrial Fibrillation Ablation, Persistent Atrial Fibrillation, Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07411378
Testing the Efficacy, Safety, and PK of 20E in Patients With Obesity Who Are Starting Treatment With the GLP-1 Agonist Semaglutide for Weight Loss.
Not yet reported Biophytis 164 participants Est. completion 2027-08Other conditions: Muscle Wasting, Obesity & Overweight, ObesityView official trial listing → -
Completed NCT NCT07417618
INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)
Brigham and Women's Hospital 60000 participants Est. completion 2026-06-19 1 siteType 2 diabetesCardiovascular disease Other conditions: OverweightView official trial listing → -
Active, not recruiting NCT NCT07431086
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity in the US
Not yet reported Regeneron Pharmaceuticals 120 participants Est. completion 2026-12-18 3 sitesOther conditions: Overweight or ObesityView official trial listing → -
Active, not recruiting NCT NCT07438444
A Study of Tirzepatide (LY3298176) in Adult Participants in India With Either Type 2 Diabetes Mellitus or Obesity
Not yet reported Eli Lilly and Company 344 participants Est. completion 2027-07 21 sitesType 2 diabetes Other conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT07439536
Dose Optimization of Sitagliptin and Duloxetine in Diabetic Cirrhosis
Not yet reported Kafrelsheikh University 64 participants Est. completion 2025-10-01 1 siteOther conditions: Liver Cirrhosis With DiabetesView official trial listing → -
Active, not recruiting NCT NCT07446998
Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss
Not yet reported Veru Inc. 239 participants Est. completion 2027-12 13 sites Stand-aloneOther conditions: Obesity & Overweight, Mobility Disability, HOMA-IRView official trial listing → -
Completed NCT NCT07455825
A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants Aged 18 to 55 Years
Not yet reported AstraZeneca 65 participants Est. completion 2026-06-01 2 sitesOther conditions: Healthy ParticipantsView official trial listing → -
Active, not recruiting NCT NCT07457424
Direct Measurement of Microstructure of Ingestive Behaviour After Initiation of GLP-1 Receptor Agonist Treatment at Maximum Dose (DIGRAT)
University College Dublin 140 participants Est. completion 2027-01-31 1 siteOther conditions: Metabolic Disease, Obesity & OverweightView official trial listing → -
Active, not recruiting NCT NCT07458269
Efficacy and Safety of Ribupatide (KAI-9531) Administered Once Weekly in Participants Living With Obesity Who Do Not Have Diabetes
Not yet reported Kailera 264 participants Est. completion 2027-06 35 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT07465926
Early Add-On Combination of GLP-1 Receptor Agonist and SGLT2 Inhibitor in People With Cardiovascular-Kidney-Metabolic Stage 2-3
Chung Shan Medical University 451036 participants Est. completion 2026-01-31Metabolic syndromeCardiovascular diseaseType 2 diabetes Other conditions: Kidney Disease, Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07468552
Trial of Tirzepatide for the Treatment of Cannabis Use Disorder
Not yet reported National Institute on Drug Abuse (NIDA) 100 participants Est. completion 2028-11-15Other conditions: Cannabis Use DisorderView official trial listing → -
Not yet recruiting NCT NCT07483801
DECODE - Haemodynamic Effects Of Semaglutide and Tirzepatide - a Series of Pilot Studies
Not yet reported Cambridge University Hospitals NHS Foundation Trust 112 participants Est. completion 2028-04 1 siteCardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07491133
Effect of Ambient Temperature on Blood Glucose and Insulin Absorption in Adults With Type 1 Diabetes
Not yet reported Institut de Recherches Cliniques de Montreal 30 participants Est. completion 2027-07 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT07492563
Safety and Effectiveness of Tirzepatide in Patients With Obesity at Hospital de Clínicas, Paraguay
LABORATORIOS INDUFAR 300 participants Est. completion 2027-10 1 siteType 2 diabetes Other conditions: Obesity, Overweight With ComorbiditiesView official trial listing → -
Active, not recruiting NCT NCT07497880
Efficacy and Safety of Oral KAI-7535 in Adult Participants Living With Obesity or Overweight With at Least 1 Weight-Related Comorbidity
Not yet reported Kailera 306 participants Est. completion 2027-07-07 36 sitesOther conditions: Obesity, OverweightView official trial listing → -
Not yet recruiting NCT NCT07504172
Real-world Effectiveness and Dosing Patterns of Tirzepatide in People With Obesity
Radboud University Medical Center 1700 participants Est. completion 2026-08-01 10 sitesOther conditions: Overweight , Obesity, Obesity (Disorder)View official trial listing → -
Not yet recruiting NCT NCT07505134
Exploring the Influence of Glucagon-like Peptide -1 (GLP-1) Medications on Food Cravings, Food Selection, and Food Intake Following Exposure to Food Advertisements
Not yet reported Penn State University 50 participants Est. completion 2026-09Other conditions: GLP - 1View official trial listing → -
Not yet recruiting NCT NCT07511543
Glucagon-like Peptide-1 Receptor Agonists for Endovascular Stroke Thrombectomy
Not yet reported Population Health Research Institute 100 participants Est. completion 2029-01-31Cardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07537686
Glucagon-like Peptide 2 (GLP-2) in Undernourished Women Improving From Histology-Confirmed Environmental Enteric Dysfunction (EED)
Not yet reported International Centre for Diarrhoeal Disease Research, Bangladesh 55 participants Est. completion 2027-12-30Other conditions: Environmental Enteric DysfunctionView official trial listing → -
Completed NCT NCT07539584
Adiponectin in Patients With Metabolic Disorders
Not yet reported Moscow Regional Research and Clinical Institute (MONIKI) 130 participants Est. completion 2024-04-08 1 siteType 2 diabetes Other conditions: Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD)View official trial listing → -
Not yet recruiting NCT NCT07547878
Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)
Not yet reported Baylor Research Institute 64 participants Est. completion 2029-03-31 1 siteChronic kidney diseaseType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07553299
A Study of Weekly Oral Dose of Ecnoglutide (VRB-101) for Weight Maintenance in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
Not yet reported Verdiva Bio Dev Limited 120 participants Est. completion 2026-12-31 20 sitesOther conditions: Obesity, Overweight, Weight MaintenanceView official trial listing → -
Not yet recruiting NCT NCT07555730
AI-assisted Multi-domain Lifestyle Versus Tirzepatide for Weight Loss Maintenance in Adults With Type 2 Diabetes (AIM-MAINTAIN)
Not yet reported Huazhong University of Science and Technology 400 participants Est. completion 2028-09-30 1 siteType 2 diabetes Other conditions: Weight Loss MaintenanceView official trial listing → -
Not yet recruiting NCT NCT07558603
Evaluate the Safety and Efficacy of AGE Serum in Post-menopausal Patients on Hormone Replacement Therapy Taking Glucagon-like Peptide-1 Agonist
Not yet reported Goldman, Butterwick, Fitzpatrick and Groff 50 participants Est. completion 2026-11-30 1 site Added to GLP-1Other conditions: Laxity; SkinView official trial listing → -
Not yet recruiting NCT NCT07567378
CARTIZ Registry: Cartilage, Arthropathy and Imaging Under Tirzepatide in Zone-stratified Cohorts - A Four-Institute Mexican Observational Registry
JULIO GRANADOS MONTIEL 30 participants Est. completion 2029-05 1 siteType 2 diabetesMetabolic syndromeHeart failureCardiovascular disease Other conditions: Psoriatic Arthritis, Osteoarthitis, Knee, Diabetes (DM), Obesity (Disorder), Insulin Resistance Syndrome, Preserved Ejection Fraction, Atrial Fibrillation (AF), Non Alcholic Fatty Liver Disease, Sarcopenia, PericardiumView official trial listing → -
Not yet recruiting NCT NCT07588984
GLP-1 Medication & Behavioral Health Programs on Weight & Metabolic Outcomes: FLOURISH and THRIVE Prospective Cohort Study
Noom Inc. 2310 participants Est. completion 2029-05 1 siteCardiovascular disease Other conditions: Obesity & Overweight, Weight Loss, Preventative Health, Body WeightView official trial listing → -
Active, not recruiting NCT NCT07590219
Use of Liraglutide in Children Aged 6 to 12 Years With Severe Obesity
Not yet reported University of Sao Paulo General Hospital 30 participants Est. completion 2028-04 1 siteOther conditions: Severe Obesity, Cardiovascular Function, Liraglutide, Childhood Obesity, Echocardiography, Speckle TrackingView official trial listing → -
Not yet recruiting NCT NCT07595575
The Effects of LEUVATE on Glycemia, Insulinemia, Aminoacidemia, and Protein Synthesis in GLP-1 RA-treated Adults
Not yet reported Nutraceutical Innovations LLC 8 participants Est. completion 2026-12-01Other conditions: The Whole-body Protein Synthesis Response to Protein With Amino Acid or Amino AcidsView official trial listing → -
Not yet recruiting NCT NCT07599046
Fecal Microbiota Transplantation (FMT) Combined With Calorie-Restricted Diet and Semaglutide in Patients With Obesity and Type 2 Diabetes
Not yet reported Eighth Affiliated Hospital, Sun Yat-sen University 20 participants Est. completion 2029-12-30 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07605247
Tirzepatide in the Treatment of Endometrial Cancer
Not yet reported Rutgers, The State University of New Jersey 30 participants Est. completion 2028-01Other conditions: Endometrial CancerView official trial listing → -
Not yet recruiting NCT NCT07605390
RAndomized EHR-based Prescribing to Improve Disease-modifying Therapies for Cardio-Kidney-Metabolic Care (RAPID-CKM)
Not yet reported Baylor Research Institute 600 participants Est. completion 2028-01 2 sitesChronic kidney diseaseType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07611552
Effects of Inulin on Cardiometabolic Risk Factors in Individuals Using Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA ) Medications for Weight Loss
Not yet reported Huazhong University of Science and Technology 600 participants Est. completion 2026-11 5 sitesOther conditions: Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07614412
SHIELD-T1D: Shingrix and GLP-1 Agonist for Beta-Cell Preservation in Recent-Onset Type 1 Diabetes.
Not yet reported Ministry of Health, Saudi Arabia 240 participants Est. completion 2028-12-31 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT07619508
Tirzepatide vs Semaglutide in Individuals at Cardiovascular Risk But Without Diabetes.
Brigham and Women's Hospital 100000 participants Est. completion 2026-06-01 1 siteOther conditions: Obesity, OverweightView official trial listing → -
Completed NCT NCT07623148
GLP-1 RA Cessation and Gastric Ultrasound Findings
Wonkwang University Hospital 186 participants Est. completion 2026-08-04 1 siteOther conditions: Residual Gastric Contents, Delayed Gastric EmptyingView official trial listing → -
Completed NCT NCT07628556
Antidiabetic Medications and Risk of Cancer
University of Pecs 74799 participants Est. completion 2025-12-30 1 siteOther conditions: CancerView official trial listing → -
Not yet recruiting NCT NCT07630454
Tirzepatide on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With Obesity and HFpEF
Not yet reported Yunlong Wang 602 participants Est. completion 2029-12-01 1 siteHeart failure Other conditions: Atrial Fibrillation, TirzepatideView official trial listing → -
Enrolling by invitation NCT NCT07640139
Estimating the Impact of Obesity Medications on Clinical and Economic Outcomes
Indiana University 125000 participants Est. completion 2029-12-31 1 siteOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07642635
Glucagon-Like Peptide-1 Receptor Agonists to Attenuate Metabolic Risk in Individuals With Duchenne Muscular Dystrophy
Not yet reported, Not yet reported Vanderbilt University Medical Center 30 participants Est. completion 2030-12 1 siteOther conditions: Duchenne Muscular Dystrophy (DMD)View official trial listing → -
Not yet recruiting NCT NCT07654062
Mazdutide for Adults With Prediabetes: A Randomized, Double-Blind, Placebo-Controlled Trial (DREAM-PRE)
Not yet reported Shandong Provincial Hospital 150 participants Est. completion 2029-07 1 sitePrediabetesView official trial listing → -
Not yet recruiting NCT NCT07671248
Tirzepatide in the Treatment of Cannabis Use Disorder
Not yet reported McMaster University 15 participants Est. completion 2028-07-31 1 siteOther conditions: Cannabis Use Disorder, Moderate, Cannabis Use Disorder, SevereView official trial listing → -
Not yet recruiting NCT NCT07676331
Clinical Study of Local and Systemic Biological Impact of GLP1/GIP-Receptor Agonists in Patients With Breast Cancer: The CLARA Trial
Not yet reported Universitaire Ziekenhuizen KU Leuven 168 participants Est. completion 2028-05-01Other conditions: Hormone-receptor-positive Breast Cancer, Early Breast CancerView official trial listing → -
Completed NCT NCT07677865
GLP-1 Receptor Agonists and Alzheimer's Disease: A Multi-National Target Trial Emulation
West China Hospital 213891 participants Est. completion 2026-06-24 1 siteType 2 diabetes Other conditions: Alzheimer Disease, Obesity & OverweightView official trial listing → -
Completed NCT NCT07682857
Effects of an Arabinoxylan-enriched Rusk on Postprandial Glucose, Insulin, Glucagon-like Peptide-1 and Appetite Responses
Not yet reported University of Turin, Italy 10 participants Est. completion 2026-04-30 1 siteOther conditions: Healthy Adult ParticipantsView official trial listing → -
Enrolling by invitation NCT NCT07687589
The Antiemetic Effects of Increased Splanchnic Perfusion, Induced by the Gut Hormone GIP, in Healthy Individuals
Not yet reported University of Copenhagen 14 participants Est. completion 2027-04-28 1 siteOther conditions: EmesisView official trial listing → -
Enrolling by invitation NCT NCT07693608
An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use Disorder
Not yet reported University of Texas Southwestern Medical Center 45 participants Est. completion 2030-03-01 1 siteOther conditions: Obesity, Methamphetamine Use Disorder, Cocaine Use Disorder, Stimulant Use DisordersView official trial listing → -
Not yet recruiting NCT NCT07697391
AI-Assisted Lifestyle Intervention Versus Tirzepatide for Obesity and Newly Diagnosed Type 2 Diabetes
Not yet reported The First Affiliated Hospital of Anhui Medical University 285 participants Est. completion 2028-01-31 2 sitesType 2 diabetes Other conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07700030
High-protein plUs reSistance Training in gLucagon-like pEptide 1 Receptor Agonist Users (HUSTLE)
Not yet reported NYU Langone Health 32 participants Est. completion 2027-12 1 siteOther conditions: Weight LossView official trial listing → -
Completed NCT NCT07701005
Non-Invasive Hepatic and Metabolic Index Changes After Incretin Therapy in Overweight/Obesity
Goztepe Prof Dr Suleyman Yalcın City Hospital 154 participants Est. completion 2026-04-15 1 siteOther conditions: Steatosis of Liver, Metabolic Liver Injury, Obesity, Overweight, Insulin ResistanceView official trial listing → -
Not yet recruiting NCT NCT07701460
Assessing Follow up Trajectories in Eating, Routines, and Weight After GLP-1
Not yet reported Tufts University 200 participants Est. completion 2028-07-31 1 siteOther conditions: Weight MaintenanceView official trial listing → -
Not yet recruiting NCT NCT07706088
Effect of Tirzepatide on Diabetic Peripheral Sensorimotor Neuropathy
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 40 participants Est. completion 2028-07-01Other conditions: Neuropathy, Small Fiber, Diabete MellitusView official trial listing → -
Enrolling by invitation NCT NCT07707778
Tirzepatide's Effects on Epigenetic Aging and Metabolic Restoration in Virally Suppressed People With HIV
Not yet reported National Taiwan University Clinical Trial Center 60 participants Est. completion 2027-12 1 siteMASLDMetabolic syndrome Other conditions: Human Immunodeficiency Virus (HIV), Dyslipidaemia, Diabetes Mellitus, Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07715929
Effect of Tirzepatide on Recurrence of Atrial Fibrillation After Catheter Ablation in Obese Patients
Not yet reported Yunlong Wang 710 participants Est. completion 2029-12-30Other conditions: Atrial Fibrillation, Obesity & Overweight, Catheter AblationView official trial listing → -
Not yet recruiting NCT NCT07723820
Glycemic Velocity and Early Retinal Microvascular Change With GLP-1RA Versus SGLT2i Initiation in Type 2 Diabetes (GLIDE)
Thammasat University Hospital 126 participants Est. completion 2027-09-01 1 siteType 2 diabetes Other conditions: Diabetic Retinopathy (DR)View official trial listing → -
Not yet recruiting NCT NCT07728318
Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients
Not yet reported Akhtar Saeed Medical and Dental College 52 participants Est. completion 2027-05-12Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07734792
Tirzepatide in Thrombectomy-Treated Acute Ischemic Stroke: A Randomized Trial
Not yet reported, Not yet reported yifang zhu 726 participants Est. completion 2028-07-31 1 siteCardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07738276
Evaluation of the Efficacy and Safety of Tirzepatide, a Dual GLP-1/GIP Agonist, on Functional Capacity in Reduced Ejection Fraction Heart Failure Patients With Obesity
Not yet reported Shahid Beheshti University of Medical Sciences 60 participants Est. completion 2027-12-22Heart failure Other conditions: Obesity & Overweight, TirzepatideView official trial listing → -
Not yet recruiting NCT NCT07747805
GLP-1 Agonists for Lung Function Improvement and Muscle Restoration in COPD
Not yet reported The Cleveland Clinic 30 participants Est. completion 2029-08-15 1 siteOther conditions: COPD, Obesity & Overweight, SarcopeniaView official trial listing → -
Not yet recruiting NCT NCT07755085
GLP-1s in Hip and Knee Arthroplasty
Not yet reported Nova Scotia Health Authority 100 participants Est. completion 2028-12 1 siteOther conditions: Arthritis, Obesity & Overweight, GLP - 1View official trial listing → -
Not yet recruiting NCT NCT07756359
Tirzepatide for Ileal Pouch-anal Anastomosis (IPAA) and Chronic High Bowel Frequency (I8F-NS-X008)
Not yet reported University of North Carolina, Chapel Hill 20 participants Est. completion 2027-09 5 sitesOther conditions: Pouch, Ileal, Pouches, Ileoanal, Bowel Diseases, InflammatoryView official trial listing → -
Not yet recruiting NCT NCT07759258
Plasma GLP-2 Dynamics and Acute Radiation Enteritis After Abdominopelvic Radiotherapy
Wang Xinying 50 participants Est. completion 2027-10-28Other conditions: Radiation EnteritisView official trial listing → -
Not yet recruiting NCT NCT07760532
Comparing Facial Aging Between Identical Twins With 3D Imaging
Ponsky Facial Aesthetics And Plastic Surgery, Llc 200 participants Est. completion 2026-09 1 siteOther conditions: Facial Skin Aging, Facial Volume Loss, Wrinkle AppearanceView official trial listing → -
Not yet recruiting NCT NCT07767552
Mazdutide for Remission of Type 2 Diabetes: Multicentre, Double Blind, Randomised, Placebo Controlled Trial
Not yet reported Yanbing Li 249 participants Est. completion 2029-06-30 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07770152
Semaglutide in Youth With Autism Spectrum Disorder
Not yet reported Children's Hospital Medical Center, Cincinnati 42 participants Est. completion 2029-09-01 1 site Stand-aloneOther conditions: Autism Spectrum Disorder, ObesityView official trial listing → -
Not yet recruiting NCT NCT07770906
Effect of GLP-1 Receptor Agonists on Periodontal Health and Response to Nonsurgical Periodontal Therapy
Not yet reported Cukurova University 40 participants Est. completion 2027-12-01Other conditions: Periodontal Disease, Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07771166
Effects of N-Acyl Taurines on Incretin Levels in Healthy Subjects
Not yet reported University Hospital, Gentofte, Copenhagen 18 participants Est. completion 2028-12Other conditions: Cardiometabolic ConditionsView official trial listing → -
Not yet recruiting NCT NCT07782359
Impact of Using a GLP1 on Treatment Related Side Effects of Lung Cancer Patients Receiving Lorlatinib
Not yet reported University of Chicago 30 participants Est. completion 2030-06 1 siteOther conditions: Lung CancerView official trial listing → -
Not yet recruiting NCT NCT07783113
Dietary Supplement for Telogen Effluvium Associated With GLP-1 Receptor Agonist Use
Not yet reported Farmoquimica S.A. 48 participants Est. completion 2027-02 1 siteOther conditions: AlopeciaView official trial listing → -
Not yet recruiting NCT NCT07787936
GLP-1/GIP Receptor Agonists in Obesity-Related HFpEF: The GLIDE-HF Registry
Miedziowe Centrum Zdrowia SA 150 participants Est. completion 2033-01-01 1 siteHeart failure Other conditions: Obesity, Pulmonary Hypertension, Iron DeficiencyView official trial listing → -
Not yet recruiting NCT NCT07796204
Ability of Almonds to Improve Nutrition During GLP-1 Treatment
Not yet reported Pennington Biomedical Research Center 76 participants Est. completion 2028-12-01 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07796477
A Study of SYH2069 Injection in Participants With T2DM Not Controlled With Diet/Exercise Alone or Metformin
Not yet reported CSPC Ouyi Pharmaceutical Co., Ltd. 240 participants Est. completion 2027-10-19 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07798284
A Clinical Trial of TQF3250 Capsules in Overweight/Obese Trial Participants With Poor Weight Control Through Simple Lifestyle Intervention
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 80 participants Est. completion 2027-04 10 sitesOther conditions: Overweight/ObesityView official trial listing → -
Not yet recruiting NCT NCT07811895
Dual GIP/GLP-1 Receptor Agonist in Obese Women Before Frozen Embryo Transfer
Not yet reported RenJi Hospital 1510 participants Est. completion 2030-12 1 siteOther conditions: Tirzepatide, Frozen Embryo Transfer, ObesityView official trial listing → -
Not yet recruiting NCT NCT07812636
Tirzepatide and Levonorgestrel IUD Therapy for EIN and Early-Stage Endometrial Cancer
Not yet reported Milton S. Hershey Medical Center 15 participants Est. completion 2028-08-01 1 siteOther conditions: Grade 1 Endometrial Endometrioid Carcinoma, Endometrial Intraepithelial Neoplasia, Metabolic ComorbiditiesView official trial listing → -
Not yet recruiting NCT NCT07816744
Danish Trial of Weight Loss to Reduce Atrial Fibrillation Progression
Not yet reported Axel Brandes 480 participants Est. completion 2030-09 2 sitesOther conditions: Atrial Fibrillation (AF), Obesity & OverweightView official trial listing → -
Not yet recruiting NCT NCT07817823
Yeast Protein Supplementation and Muscle Preservation During GLP-1RA-Induced Weight Loss
Not yet reported Huazhong University of Science and Technology 200 participants Est. completion 2027-05-30 1 siteOther conditions: Overweight and Obesity in Adults Receiving GLP-1RA TreatmentView official trial listing → -
Not yet recruiting NCT NCT07817875
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
Not yet reported Eli Lilly and Company 150 participants Est. completion 2032-12 84 sitesOther conditions: ObesityView official trial listing → -
Not yet recruiting NCT NCT07818226
Effects of GLP-1 Receptor Agonists on Saliva and Oral Health
Kırıkkale University 50 participants Est. completion 2027-12-15 1 siteType 2 diabetes Other conditions: Obesity & Overweight, Xerostomia, Dental CariesView official trial listing → -
Completed NCT NCT07820111
Comparative Study of Different Weekly GLP-1 Receptor Agonists Among Diabetic and Non-Diabetic Patients: Clinical Trial
Not yet reported Zagazig University 159 participants Est. completion 2026-03-17 1 siteOther conditions: Obese Diabetics, Obese Non DiabeticView official trial listing → -
Not yet recruiting NCT NCT07824895
Mazdutide for Weight Management and Gout in Adults With Obesity
Not yet reported Hongwei Jiang 30 participants Est. completion 2028-03-31Metabolic syndrome Other conditions: Gout, Obesity (BMI>30), HyperuricemiaView official trial listing → -
Not yet recruiting NCT NCT07825857
Randomized Controlled Trial of Tirzepatide for Methamphetamine Use Disorder
Not yet reported University of Texas Southwestern Medical Center 228 participants Est. completion 2031-08 4 sitesOther conditions: Methamphetamine Use DisorderView official trial listing → -
Not yet recruiting NCT NCT07829198
Efficacy of Tirzepatide for Weight Management in Patients With Suboptimal Weight Loss After Bariatric Surgery: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Not yet reported Universidade do Porto 70 participants Est. completion 2028-12 3 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT07834398
Weekly GLP-1 Receptor Agonists in Obese Individuals Without Diabetes
Not yet reported Zagazig University 150 participants Est. completion 2026-04-21 1 siteOther conditions: Non-diabetec Obesity, Obesity (Disorder)View official trial listing → -
Not yet recruiting NCT NCT07842393
A Study of IBI3042 in Healthy Adult Participants
Not yet reported Fortvita Biologics (USA)Inc. 32 participants Est. completion 2027-02-03 1 siteOther conditions: Healthy Volunteers (HV)View official trial listing → -
Not yet recruiting NCT NCT07845500
A Study to Learn About Switching to a Monthly Study Medicine Called Berobenatide (PF-08653944) to Help Keep Weight Off in People With Overweight or Obesity
Not yet reported Pfizer 660 participants Est. completion 2028-02-16 8 sitesOther conditions: Obesity, Overweight and/or Obesity, Overweight, Treatment Of ObesityView official trial listing → -
Not yet recruiting NCT NCT07846865
Tirzepatide Versus Positive Airway Pressure for the Treatment of Obstructive Sleep Apnoea: A Randomised Comparative Effectiveness Trial
Not yet reported, Not yet reported Woolcock Institute of Medical Research 256 participants Est. completion 2028-12-01 1 siteOther conditions: Sleep Apnoea, Obesity & Overweight, Sleep Apnea Syndrome, ObstructiveView official trial listing → -
Not yet recruiting NCT NCT07846956
NAION in Non-Diabetic Obese Patients Using GLP-1 Receptor Agonists: A Real-World Study
Istanbul Saglik Bilimleri University 28 participants Est. completion 2026-11-30 1 siteOther conditions: Non-arteritic Anterior Ischemic Optic Neuropathy Obesity, ObesityView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
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