GLP-1 Market
LLY $1188.72 ▲ +2.7% NVO $38.26 ▲ +1.9% PFE $28.00 ▲ +1.8% VKTX $28.54 ▲ +0.6% KLRA $10.53 ▼ -2.8% GPCR $26.68 ▼ -2.9% RHHBY $53.97 ▲ +2.7%
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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Glibenclamide

Company
Assistance Publique - Hôpitaux de Paris
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
2 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

2 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Oct 8, 2026

Find a Clinical Trial Near Me

See recruiting studies for Glibenclamide and check eligibility with the study team.

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Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

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Trial details
  • Recruiting NCT NCT05426681

    Spinal Cord Injury Neuroprotection With Glyburide

    Not yet reported Francis Farhadi 12 participants Est. completion 2028-05 1 site
    Other conditions: Acute Spinal Cord Injury
    View official trial listing →
  • Recruiting NCT NCT07802561

    Comparison of Metformin Versus Glyburide for Blood Sugar Control in Women With Gestational Diabetes

    Not yet reported Nishtar Medical University 92 participants Est. completion 2026-10-17 1 site
    Other conditions: Gestational Diabetes Mellitus (GDM)
    View official trial listing →
  • Completed NCT NCT00035542

    A Research Study to Determine the Safety and Efficacy of Glucovance Compared to Metformin and Glyburide in Children and Adolescents With Type 2 Diabetes.

    Not yet reported Bristol-Myers Squibb Est. completion 2003-10 50 sites
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00035568

    A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes

    Not yet reported Bristol-Myers Squibb Est. completion 2003-06 9 sites
    Other conditions: Diabetes Mellitus, Non-Insulin-Dependent
    View official trial listing →
  • Completed NCT NCT00046462

    Determine Whether Glycemic Control is Different Between Lantus & a 3rd Oral Agent When Failure With Other Treatment

    Not yet reported Sanofi 240 participants Est. completion 2004-12 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00123643

    Vascular Effects of Rosiglitazone Versus Glyburide in Type 2 Diabetic Patients

    Not yet reported St. Paul Heart Clinic 36 participants Est. completion 2005-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT00160485

    Glyburide Compared to Insulin in the Management of White's Classification A2 Gestational Diabetes

    Not yet reported Tripler Army Medical Center Est. completion 2010-06 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT00162175

    PPAR-COMBO With Sulfonylurea

    Not yet reported Bristol-Myers Squibb 534 participants Est. completion 2005-11 149 sites
    Other conditions: Metabolics Diabetes Nos
    View official trial listing →
  • Completed NCT NCT00184821

    Ischemic Injury and Ischemic Preconditioning in Diabetes

    Radboud University Medical Center 20 participants Est. completion 2005-05 1 site
    Other conditions: Diabetes Mellitus, Insulin-Dependent, Ischemia-Reperfusion Injury
    View official trial listing →
  • Completed NCT NCT00194896

    Preferred Treatment of Type 1.5 Diabetes

    Not yet reported University of Washington 64 participants Est. completion 2008-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00232583

    Preservation of Beta-cell Function in Type 2 Diabetes Mellitus

    Not yet reported University of Texas Southwestern Medical Center 58 participants Est. completion 2011-12 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00238472

    A Pilot Study to Evaluate the Effects of Nateglinide vs. Glibenclamide on Renal Hemodynamics and Albumin Excretion

    Not yet reported Novartis Pharmaceuticals 24 participants Est. completion 2005-06
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00251940

    GALLANT 7 Tesaglitazar Add-on to Sulphonylurea

    Not yet reported AstraZeneca 555 participants Est. completion 2006-03 84 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00255541

    GALLANT 4 Tesaglitazar vs. Glibenclamide

    Not yet reported AstraZeneca 580 participants Est. completion 2006-12 66 sites
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT00267683

    Efficacy and Safety of Insulin Aspart Versus Glibenclamide in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 9 participants Est. completion 2006-04
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00279045

    Diabetes Study With Rosiglitazone Monotherapy Versus Metformin Or Glyburide/Glibenclamide

    Not yet reported GlaxoSmithKline 4426 participants Est. completion 2006-06-19 490 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00286468

    Study of Alogliptin Combined With Sulfonylurea in Subjects With Type 2 Diabetes Mellitus.

    Not yet reported Takeda 500 participants Est. completion 2007-06 68 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT00300105

    GALLEX 4 - Long-Term Extension Study to Evaluate Tesaglitazar Therapy in Patients With Type 2 Diabetes

    Not yet reported AstraZeneca 400 participants Est. completion 2006-12 42 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00313313

    A Study of Saxagliptin in Subjects With Type 2 Diabetes Who Have Inadequate Blood Sugar Control With Sulfonylureas

    Not yet reported AstraZeneca 768 participants Est. completion 2008-09 115 sites
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00333723

    AVANDIA With Glyburide In African American And Hispanic Patients With Type 2 Diabetes Not Controlled by Glyburide Alone

    Not yet reported GlaxoSmithKline 245 participants Est. completion 2003-01-06
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00347100

    Insulin Glargine in Type 2 Diabetic Patients

    Not yet reported Sanofi 387 participants 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00371306

    Comparison of Glucovance to Insulin for Diabetes During Pregnancy

    Not yet reported Regional Obstetrical Consultants 200 participants Est. completion 2008-09 1 site
    Type 2 diabetes Other conditions: Gestational Diabetes, Pregnancy
    View official trial listing →
  • Completed NCT NCT00379769

    RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes

    Not yet reported GlaxoSmithKline 4447 participants Est. completion 2008-12 446 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00388986

    A Drug-Drug Interaction Study of GK Activator (2) and Glyburide in Patients With Type 2 Diabetes.

    Not yet reported Hoffmann-La Roche 18 participants Est. completion 2007-07 4 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00393718

    Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 400 participants Est. completion 2008-05 1 site Added to GLP-1
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT00417729

    Effects of Acarbose Versus Glibenclamide on MAGE and Oxidative Stress in Patients With Type 2 DM

    Not yet reported Taichung Veterans General Hospital 51 participants Est. completion 2009-01 1 site
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00434772

    Glucagon in the Treatment of Hypoglycemia in Newborn Infants of Diabetic Mothers

    Not yet reported Shaare Zedek Medical Center Est. completion 2009-05 1 site
    Other conditions: Hypoglycemia
    View official trial listing →
  • Completed NCT NCT00451620

    Effect of GlucoNorm vs Glyburide on Post-Prandial Hyperglycemia in Elderly Subjects With Type 2 Diabetes

    Not yet reported University of British Columbia 30 participants Est. completion 2011-09 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT00472875

    Do Sulphonylureas Preserve Cortical Function During Hypoglycaemia?

    Not yet reported King's College Hospital NHS Trust 10 participants 1 site
    Other conditions: Type 1 Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00486187

    Effects of ROSIglitazone on Inflammatory Markers and Adipokines in Diabetic Patients Using an Angiotensin Receptor Blocker (TELmisartan) - The ROSITEL Study

    Not yet reported Dr. Milan Gupta 103 participants Est. completion 2009-06 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00494312

    Safety Study of Pioglitazone Compared To Glyburide on Liver Function

    Not yet reported Takeda 2120 participants Est. completion 2005-06
    Other conditions: Diabetes Mellitus, Liver
    View official trial listing →
  • Completed NCT NCT00515801

    Sulfonylurea Effects on Glucagon Regulation During Hypoglycemia in Type 1 DM

    Not yet reported, Not yet reported University Hospital, Basel, Switzerland 18 participants 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT00521742

    Efficacy of Pioglitazone Compared to Glyburide in Treating Subjects With Type 2 Diabetes Mellitus and Mild Cardiac Disease

    Not yet reported Takeda 300 participants Est. completion 2003-01
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Terminated NCT NCT00521820

    Safety Comparison of Pioglitazone and Glyburide in Type 2 Diabetes Subjects With Mild to Moderate Congestive Heart Failure

    Not yet reported Takeda 518 participants Est. completion 2003-10
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00541437

    Type 2 Diabetes Patients Switched From Sulfonylurea With Metformin to Glyburide/Metformin Combination Tablet

    Genovate Biotechnology Co., Ltd., 12 participants Est. completion 2007-02 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00549874

    Effect of Rosiglitazone on Myocardial Blood Flow Regulation in Type 2 Diabetes

    Not yet reported University of Michigan 27 participants Est. completion 2006-11 2 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00608179

    Glimepiride Induced Insulin Secretion Will be Inhibited by Hypoglycemia

    Not yet reported Vanderbilt University 32 participants Est. completion 2010-12
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00610038

    Efficacy and Safety Study of Sulfonylureas in Neonatal Diabetes Mellitus

    Not yet reported Assistance Publique - Hôpitaux de Paris 19 participants Est. completion 2011-12 1 site Stand-alone
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT00696982

    The Effect of Sitagliptin on Hypertension, Arterial Stiffness, Oxidative Stress and Inflammation

    Not yet reported Assaf-Harofeh Medical Center 60 participants Est. completion 2009-06 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Arterial Stiffness
    View official trial listing →
  • Status unknown NCT NCT00700856

    Thiazolidinediones Or Sulphonylureas and Cardiovascular Accidents.Intervention Trial

    Not yet reported Italian Society of Diabetology 3371 participants Est. completion 2018-12 61 sites
    Type 2 diabetesCardiovascular disease
    View official trial listing →
  • Completed NCT NCT00734669

    Risk of Hypoglycemia in Type 2 Diabetes

    University of Giessen 12 participants Est. completion 2016-10
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT00744965

    Treatment of Mild Gestational Diabetes With Glyburide Versus Placebo

    Not yet reported University of Texas Southwestern Medical Center 395 participants Est. completion 2016-01 1 site
    Other conditions: Mild Gestational Diabetes
    View official trial listing →
  • Terminated NCT NCT00759720

    Efficacy and Safety of TAK-559 Combined With Glyburide in Treating Subjects With Type 2 Diabetes Mellitus.

    Not yet reported Takeda 447 participants Est. completion 2004-12
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00770835

    Efficacy and Safety of Pioglitazone in Treating Subjects With Vascular Complications Associated With Type 2 Diabetes Mellitus.

    Not yet reported Takeda 39 participants Est. completion 2011-05 2 sites
    Other conditions: Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT00835991

    Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fed

    Not yet reported Teva Pharmaceuticals USA 60 participants Est. completion 2003-02 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00836472

    Glyburide/Metformin 5 mg/500 mg Film-Coated Tablets, Fasting

    Not yet reported Teva Pharmaceuticals USA 60 participants Est. completion 2003-04 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00864734

    A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Non-fasting Conditions

    Not yet reported Actavis Inc. 24 participants Est. completion 2002-11 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865241

    A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 36 participants Est. completion 2002-11 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00865436

    A Relative Bioavailability Study of Glyburide/Metformin HCl 5 mg/500 mg Tablets Under Fasting Conditions

    Not yet reported Actavis Inc. 36 participants Est. completion 2004-04 1 site
    Other conditions: Healthy
    View official trial listing →
  • Withdrawn NCT NCT00935363

    Interplay Between Organic Anion Transporting Polypeptide (OATP) Transporters Transporters and CYP2C9 in Glyburide Pharmacokinetics (PK)

    Not yet reported University of California, San Francisco Est. completion 2010-04
    Other conditions: Healthy
    View official trial listing →
  • Status unknown NCT NCT00935805

    Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy

    Hospital de Clinicas de Porto Alegre 124 participants Est. completion 2012-07 1 site
    Other conditions: Diabetes Mellitus, Arterial Hypertension
    View official trial listing →
  • Completed NCT NCT00965991

    Metformin Compared to Glyburide in Gestational Diabetes

    Not yet reported University of New Mexico 149 participants Est. completion 2023-08 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Terminated NCT NCT01029795

    A Study of LY2599506 (Oral Agent Medication: Glucokinase Activator 1) in Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 38 participants Est. completion 2010-06 16 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01045590

    Glibenclamide (Dose to be Titrated From Starting Dose of 5mg om) Plus Rosiglitazone 4mg om (Increased to 8mg om After 6 Months) and vs Glibenclamide (Dose to be Titrated With Starting Dose of 5mg om) Plus Placebo, Administered to Patients With Type 2 Diabetes Mellitus

    Not yet reported GlaxoSmithKline 100 participants Est. completion 2006-02 4 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01068860

    To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies

    Not yet reported Novartis 246 participants Est. completion 2010-08 52 sites
    Type 2 diabetesPrediabetes
    View official trial listing →
  • Completed NCT NCT01107717

    Durability of Combination Therapy With Exenatide/Pioglitazone/Metformin vs. Conventional Therapy in New Onset T2DM

    Not yet reported The University of Texas Health Science Center at San Antonio 318 participants Est. completion 2023-02-03 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01131182

    Study of Sitagliptin Treatment in Patients With Type 2 Diabetes During Ramadan (0431-263)

    Not yet reported Merck Sharp & Dohme LLC 1147 participants Est. completion 2010-11-04
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01132703

    Safety Study of RP-1127 (Glyburide for Injection) in Healthy Volunteers

    Not yet reported Biogen 34 participants Est. completion 2010-05-07 1 site
    Cardiovascular disease Other conditions: Traumatic Brain Injury
    View official trial listing →
  • Completed NCT NCT01145534

    Evaluation of Cissus Verticillata L. Infusion in Controlling Type 2 Diabetes

    Not yet reported, Not yet reported Federal University of Paraíba 15 participants Est. completion 2009-10 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01195259

    Malignancy Meta Analysis for BRL49653

    GlaxoSmithKline 1 participants Est. completion 2010-01
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01215331

    Gestational Diabetes: Insulin or Oral Hypoglycemic Agents?

    Not yet reported Université de Sherbrooke 73 participants Est. completion 2016-05 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT01242137

    Pharmacogenetic Effect on the Pharmacodynamics of Glibenclamide

    Assaf-Harofeh Medical Center 30 participants 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01242215

    A Study to Assess the Efficacy and Safety of ASP1941 in Combination With Sulfonylurea in Type 2 Diabetic Patients

    Not yet reported Astellas Pharma Inc 243 participants Est. completion 2012-04-25 7 sites
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01268683

    Glyburide Advantage in Malignant Edema and Stroke Pilot

    Not yet reported, Not yet reported Remedy Pharmaceuticals, Inc. 10 participants Est. completion 2012-06-07 4 sites
    Cardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT01319734

    Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus

    Not yet reported Al-Neelain University 50 participants 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01329016

    Glyburide and Metformin for Gestational Diabetes Mellitus (GDM)

    Not yet reported, Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 177 participants Est. completion 2015-02-28 4 sites
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01340768

    Study to Compare Sitagliptin Versus Sulfonylurea Treatment During Ramadan Fasting in Patients With Type 2 Diabetes (MK-0431-262)

    Not yet reported Merck Sharp & Dohme LLC 870 participants Est. completion 2011-09-21
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01357135

    An Observational Study of Type II Diabetics Treated With Dual Therapy With or Without Sitagliptin (Januvia®/Xelevia®, MK-0431-201)

    Merck Sharp & Dohme LLC 3453 participants Est. completion 2013-08-31
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01454154

    Glyburide (RP-1127) for Traumatic Brain Injury (TBI)

    Not yet reported Remedy Pharmaceuticals, Inc. 29 participants Est. completion 2015-02-20 4 sites
    Other conditions: Traumatic Brain Injury
    View official trial listing →
  • Completed NCT NCT01456650

    R230C and C230C Variants of ABCA1 and Glyburide Response

    Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 85 participants Est. completion 2012-12 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01540396

    Gestational Diabetes Diagnostic Methods

    Not yet reported University of Pittsburgh 47 participants Est. completion 2014-12 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT01563120

    A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus

    Not yet reported HaEmek Medical Center, Israel 108 participants Est. completion 2014-12 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT01584232

    A Study of Dulaglutide in Japanese Participants With Type 2 Diabetes Mellitus

    Not yet reported Eli Lilly and Company 361 participants Est. completion 2013-07 15 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01605773

    Effect of Repaglinide on Postprandial Lipemia in Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 51 participants Est. completion 2003-03-13 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01697592

    Omarigliptin (MK-3102) Clinical Trial - Add-on to Oral Antihyperglycemic Agent Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-3102-015)

    Not yet reported Merck Sharp & Dohme LLC 585 participants Est. completion 2014-05-08 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01698931

    Efficacy of Repaglinide in Subjects With Type 2 Diabetes

    Not yet reported Novo Nordisk A/S 9 participants Est. completion 2003-03-06 1 site
    Type 2 diabetes Other conditions: Diabetes
    View official trial listing →
  • Completed NCT NCT01716338

    Glyburide Healthy Volunteer Study

    Not yet reported Washington University School of Medicine 21 participants Est. completion 2014-08 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT01731431

    Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational Diabetes

    Not yet reported Assistance Publique - Hôpitaux de Paris 914 participants Est. completion 2017-06-02 1 site
    Other conditions: Diabetes, Gestational
    View official trial listing →
  • Completed NCT NCT01733108

    A Study to Assess the Effects of Canagliflozin (JNJ-28431754) on the Pharmacokinetics, Pharmacodynamics, and Safety of Glyburide in Healthy Volunteers

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 29 participants Est. completion 2008-09
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT01794182

    Glyburide Advantage in Malignant Edema and Stroke - Remedy Pharmaceuticals

    Not yet reported Remedy Pharmaceuticals, Inc. 86 participants Est. completion 2016-04-04 17 sites
    Cardiovascular disease Other conditions: Malignant Edema
    View official trial listing →
  • Completed NCT NCT01798706

    Efficacy and Safety of Lixisenatide Versus Placebo on Top of Basal Insulin and/or Oral Antidiabetic Treatment in Older Type 2 Diabetic Patients

    Not yet reported Sanofi 350 participants Est. completion 2015-02 83 sites Added to GLP-1
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT01822548

    Effect of Vildagliptin vs. Glibenclamide on Circulating Endothelial Progenitor Cell Number Type 2 Diabetes

    Not yet reported Azienda Ospedaliero-Universitaria di Parma 64 participants Est. completion 2015-01 2 sites
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT01867502

    Effects of Vildagliptin Versus Glibenclamide on Glycemia After Exercise in Patients With Type 2 Diabetes

    Not yet reported Hospital de Clinicas de Porto Alegre 20 participants Est. completion 2015-08 1 site
    Type 2 diabetes Other conditions: Hypoglycemic Agents, Diabetic Blood Glucose Monitoring, Exercise
    View official trial listing →
  • Terminated NCT NCT01934816

    Incretin and KATP Channels

    Not yet reported Katarina Kos 2 participants Est. completion 2015-10 1 site
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT01940302

    Dietary Supplement of LEHEL for the Patients With Type 2 Diabetes

    Not yet reported Shaoguan University 71 participants Est. completion 2014-03 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT01944618

    forREAL: FORXIGA PRESCRIPTION EVENT MONITORING PROGRAM (PEMP)

    AstraZeneca 5000 participants Est. completion 2015-10 1 site
    Type 2 diabetes
    View official trial listing →
  • Withdrawn NCT NCT01947699

    Glycemic Profile in Women With Gestational Diabetes Treated With Glyburide

    Not yet reported University of Pittsburgh Est. completion 2014-09 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT01998113

    Glyburide and Metformin for the Treatment of Gestational Diabetes Mellitus. Systematic Review

    Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 2509 participants Est. completion 2014-05 1 site
    Other conditions: Gestational Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02080377

    A Feasibility Study Looking at the Use of Glibenclamide and metfoRmin Versus stAndard Care in gEstational diabeteS

    Not yet reported University of Edinburgh 23 participants Est. completion 2016-03 5 sites
    Other conditions: Pregnancy, Gestational Diabetes
    View official trial listing →
  • Status unknown NCT NCT02091336

    Oral Antidiabetic Agents in Pregnancy

    Not yet reported Hospital de Clinicas de Porto Alegre 80 participants Est. completion 2016-12 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT02128022

    Cardioprotective Effects of GLP-1 and Their Mechanisms

    Not yet reported Papworth Hospital NHS Foundation Trust 32 participants Est. completion 2016-03 1 site Stand-alone
    Other conditions: Angina Pectoris
    View official trial listing →
  • Completed NCT NCT02145611

    Vildagliptin vs. Glibenclamide in Endothelial Function in Type 2 Diabetes and Hypertension

    Not yet reported Dr. José Fernando Vilela-Martin MD PhD 50 participants Est. completion 2016-05 1 site
    Type 2 diabetes Other conditions: Hypertension, Endothelial Dysfunction
    View official trial listing →
  • Completed NCT NCT02183428

    Bioavailability of BI 1356 and Glyburide in Healthy Male and Female Volunteers

    Not yet reported Boehringer Ingelheim 20 participants
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02201602

    Sulphonylurea Receptor Mutation and Responsiveness to Gliclazide - a Pilot Proof of Concept, Randomised Cross-over Study

    Not yet reported Khoo Teck Puat Hospital 8 participants Est. completion 2016-07 1 site
    Other conditions: Diabetes
    View official trial listing →
  • Status unknown NCT NCT02255006

    Effect of Acupuncture to Endothelial Dysfunction Induced by Ischemia-reperfusion Injury

    Not yet reported Kyunghee University Medical Center 36 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02297126

    A Prospective Trial to Assess Cost and Clinical Outcomes of a Clinical Pharmacogenomic Program

    Not yet reported Indiana University 4465 participants Est. completion 2019-05-03 1 site
    Other conditions: Adverse Drug Reaction
    View official trial listing →
  • Completed NCT NCT02318693

    Efficacy of Sitagliptin and Glibenclamide on the Glucose Variability in Japanese Participants With Type 2 Diabetes Mellitus (MK-0431-355)

    Not yet reported Merck Sharp & Dohme LLC 53 participants Est. completion 2015-12-15
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02375828

    Glibentek in Patients With Neonatal Diabetes Secondary to Mutations in K+-ATP Channels

    Not yet reported Assistance Publique - Hôpitaux de Paris 10 participants Est. completion 2019-07-22 1 site Stand-alone
    Other conditions: Neonatal Diabetes Secondary to Mutation in the Potassium Channel
    View official trial listing →
  • Status unknown NCT NCT02406950

    Sitagliptin and Endothelial Dysfunction

    Not yet reported Kyunghee University Medical Center 10 participants Est. completion 2015-08 1 site
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT02456428

    Incretin-based Drugs and the Risk of Heart Failure

    Canadian Network for Observational Drug Effect Studies, CNODES 1499650 participants Est. completion 2015-05 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02460874

    Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593)

    Not yet reported, Not yet reported University of Alabama at Birmingham 1 participants Est. completion 2021-05-19 1 site
    Other conditions: Cerebral Edema, Brain Metastases
    View official trial listing →
  • Completed NCT NCT02475499

    Incretin-based Drugs and Pancreatic Cancer

    Canadian Network for Observational Drug Effect Studies, CNODES 886172 participants Est. completion 2015-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02476760

    Incretin-based Drugs and Acute Pancreatitis

    Canadian Network for Observational Drug Effect Studies, CNODES 1417914 participants Est. completion 2015-04 1 site
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02524379

    Spinal Cord Injury Neuroprotection With Glyburide

    Not yet reported, Not yet reported Ohio State University 3 participants Est. completion 2021-02-08 1 site
    Other conditions: Acute Spinal Cord Injury
    View official trial listing →
  • Completed NCT NCT02607410

    Sitagliptin (DPP-4 Inhibitor) and NPH Insulin in Patients With T2D

    Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2014-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02624817

    Long-Term Sulfonylurea Response in KCNJ11 Neonatal Diabetes

    Not yet reported Haukeland University Hospital 90 participants Est. completion 2016-08 1 site Stand-alone
    Other conditions: Permanent Neonatal Diabetes Mellitus
    View official trial listing →
  • Status unknown NCT NCT02624830

    Long-Term Sulfonylurea Response in ABCC8 Neonatal Diabetes (SuResponsSUR)

    Not yet reported Haukeland University Hospital 30 participants Est. completion 2020-02 1 site Stand-alone
    Other conditions: Permanent Neonatal Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT02627898

    Effect of Green Tea Extract on Arterial Stiffness in Type 2 Diabetes Mellitus

    Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2016-12 Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02726490

    Glyburide vs Glucovance in the Treatment of GDM

    Not yet reported Texas Tech University Health Sciences Center, El Paso 7 participants Est. completion 2018-08-14 1 site
    Other conditions: Gestational Diabetes
    View official trial listing →
  • Completed NCT NCT02815787

    The Drug -Drug Interaction of SP2086 and Glyburide

    Not yet reported Jiangsu HengRui Medicine Co., Ltd. 16 participants Est. completion 2014-07 1 site
    Type 2 diabetes
    View official trial listing →
  • Completed NCT NCT02830048

    Low dosE GlibENclamide in Diabetes Part A

    Not yet reported University of Oxford 16 participants Est. completion 2017-03-09 1 site Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Terminated NCT NCT02864953

    Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

    Not yet reported Remedy Pharmaceuticals, Inc. 535 participants Est. completion 2023-08-18 250 sites
    Cardiovascular disease Other conditions: Brain Edema
    View official trial listing →
  • Completed NCT NCT02919345

    Assessment of Dapagliflozin Effect on Diabetic Endothelial Dysfunction of Brachial Artery

    Not yet reported University of Campinas, Brazil 98 participants Est. completion 2019-03 1 site
    Type 2 diabetesCardiovascular disease Other conditions: Carotid Artery Diseases
    View official trial listing →
  • Completed NCT NCT03029702

    Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus

    Not yet reported Maisa N. Feghali, MD 54 participants Est. completion 2023-08-31 1 site
    Other conditions: Gestational Diabetes, Diabetes, Gestational, Pregnancy in Diabetes
    View official trial listing →
  • Withdrawn NCT NCT03078725

    Failure Rate of GLyburide And Metformin Among Gestational Diabetics

    Not yet reported The University of Texas Health Science Center, Houston Est. completion 2018-05-10
    Other conditions: Gestational Diabetes Mellitus, Class A2
    View official trial listing →
  • Completed NCT NCT03089333

    Effects of SGLT2 Inhibitor on Hemodynamic Parameters in Resistant Hypertensive Subjects

    Not yet reported University of Campinas, Brazil 16 participants Est. completion 2017-12 1 site Stand-alone
    Type 2 diabetes Other conditions: Hypertension, Blood Pressure, Obesity, Cardiac Hypertrophy, Microalbuminuria, Vascular Stiffness
    View official trial listing →
  • Completed NCT NCT03284463

    Safety and Efficacy of Glibenclamide Combined With Rt-PA in Acute Cerebral Embolism

    Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 306 participants Est. completion 2023-05-28 8 sites
    Cardiovascular disease
    View official trial listing →
  • Completed NCT NCT03492580

    A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease

    Janssen Research & Development, LLC 714582 participants Est. completion 2018-06-25 1 site
    Type 2 diabetesCardiovascular disease
    View official trial listing →
  • Status unknown NCT NCT03569540

    Glibenclamide in Aneurysmatic Subarachnoid Hemorrhage

    Not yet reported University of Sao Paulo General Hospital 50 participants Est. completion 2019-12-01 1 site Stand-alone
    Other conditions: Subarachnoid Hemorrhage, Aneurysmal
    View official trial listing →
  • Completed NCT NCT03741530

    Glibenclamide Advantage in Treating Edema After Intracerebral Hemorrhage

    Not yet reported Xijing Hospital 220 participants Est. completion 2020-09-23 5 sites Stand-alone
    Other conditions: Intracerebral Hemorrhage
    View official trial listing →
  • Completed NCT NCT03855306

    A Bioequivalence Study of Glibenclamide From Glibesyn 5 mg Tablets (Medochemie LTD Cyprus) and Daonil 5 mg Tablets (Sanofi-Aventis Cyprus Ltd. )

    Not yet reported Genuine Research Center, Egypt 27 participants Est. completion 2018-08-15 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT03856970

    Study to Evaluate the Effect of IW-3718 on the Pharmacokinetics of Oral Contraceptive, Levothyroxine, Glyburide, and Digoxin in Healthy Adult Volunteers

    Not yet reported Ironwood Pharmaceuticals, Inc. 87 participants Est. completion 2019-07-03 1 site
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Status unknown NCT NCT03886922

    The Hemodynamics Effect of Glibenclamide on Levcromakalim Assessed by High Resolution Magnetic Resonance Angiography (MRA) Technique in a Randomized Double-blind Cross-over Placebo-controlled Study With Healthy Volunteers

    Not yet reported Danish Headache Center 15 participants Est. completion 2023-08-30 2 sites
    Other conditions: Hemodynamics of Cranial Arteries, Headache, Cerebral Blood Flow
    View official trial listing →
  • Terminated NCT NCT03954041

    A Study to Evaluate the Efficacy and Safety of BIIB093 in Participants With Brain Contusion

    Not yet reported Remedy Pharmaceuticals, Inc. 92 participants Est. completion 2023-06-27 63 sites
    Other conditions: Brain Contusion
    View official trial listing →
  • Completed NCT NCT04231617

    The Hemodynamic Effects of CGRP After Glibenclamide Administration in Healthy Volunteers

    Not yet reported Danish Headache Center 20 participants Est. completion 2020-09-01 2 sites
    Other conditions: Hemodynamics of Cranial Arteries, Headache, Cerebral Blood Flow
    View official trial listing →
  • Status unknown NCT NCT04239586

    Switching From Insulin to Sulfonylurea in Diabetes Associated With Variants in MODY Genes

    Not yet reported Haukeland University Hospital 30 participants Est. completion 2022-04 1 site
    Other conditions: Maturity-Onset Diabetes of the Young, Type 3, Maturity Onset Diabetes of the Young, Type 1, Childhood Diabetes Mellitus, Insulin-dependent Diabetes Mellitus
    View official trial listing →
  • Completed NCT NCT04859452

    A Study to Evaluate the DDI of DBPR108 With Metformin,Glibenclamide,Valsartan, or Simvastatin in Healthy Subjects

    Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 56 participants Est. completion 2021-07-09 1 site Stand-alone
    Other conditions: Healthy Subjects
    View official trial listing →
  • Completed NCT NCT04960657

    The Hemodynamic Effects of PACAP38 After Glibenclamide Administration in Healthy Volunteers

    Not yet reported Danish Headache Center 22 participants Est. completion 2021-03-19 1 site
    Other conditions: Migraine, Headache, Pain
    View official trial listing →
  • Status unknown NCT NCT05137678

    Evaluate the Use of Glibenclamide on Acute aSAH

    Not yet reported Beijing Tiantan Hospital 110 participants Est. completion 2022-12-01 1 site Stand-alone
    Other conditions: Subarachnoid Hemorrhage
    View official trial listing →
  • Status unknown NCT NCT05148403

    To Evaluate the Effect of Glibenclamide in Reducing Brain Edema of TBI

    Not yet reported, Not yet reported Beijing Tiantan Hospital 76 participants Est. completion 2022-10-01 2 sites Stand-alone
    Other conditions: Traumatic Brain Injury
    View official trial listing →
  • Status unknown NCT NCT05161429

    BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes

    Brigham and Women's Hospital 550000 participants Est. completion 2024-06-30 5 sites
    Type 2 diabetes
    View official trial listing →
  • Active, not recruiting NCT NCT05220917

    Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study

    Brigham and Women's Hospital 781430 participants Est. completion 2027-09-30 1 site
    Type 2 diabetes Other conditions: Cardiovascular Events, Renal Disease
    View official trial listing →
  • Completed NCT NCT05687500

    Oral Glibenclamide in Preterm Infants With Hyperglycaemia (GALOP)

    Not yet reported Assistance Publique - Hôpitaux de Paris 35 participants Est. completion 2026-01-08 1 site Stand-alone
    Other conditions: Transient; Hypoglycemia, Neonatal, Preterm, Glibenclamide Adverse Reaction
    View official trial listing →
  • Status unknown NCT NCT05688332

    Glycaemic & Cardiovascular Treatment Outcomes of Voglibose Vs Glibenclamide Added to Metformin in T2DM Patients

    Not yet reported University of Zambia 118 participants Est. completion 2024-01
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT05751525

    Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome

    Royal Devon and Exeter NHS Foundation Trust 21 participants Est. completion 2025-12-31 4 sites
    Other conditions: Neurodevelopmental Disorders, Intellectual Disability, Development Delay, ADHD, Autism Spectrum Disorder, Epilepsy
    View official trial listing →
  • Withdrawn NCT NCT05910554

    Investigation of the Efficacy of Metformin Therapy on Pulmonary Sarcoidosis

    Not yet reported University of Maryland, Baltimore Est. completion 2027-09-01
    Other conditions: Sarcoidosis, Pulmonary
    View official trial listing →
  • Status unknown NCT NCT06570980

    Comparative Analysis of Cost-effectiveness Between Sulfonylureas and DPP4 Inhibitors in Combination With Metformin in Treatment of Type 2 Diabetic Patients : A Retrospective, Observational Study.

    Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 200 participants Est. completion 2024-08-30 1 site
    Type 2 diabetes
    View official trial listing →
  • Status unknown NCT NCT06589141

    Comparison Between Metformin and Glyburide in the Management of Gestational Diabetes

    Not yet reported Assiut University 180 participants Est. completion 2026-06-30
    Other conditions: Gestational Diabetes Mellitus in Pregnancy
    View official trial listing →
  • Active, not recruiting NCT NCT06907472

    Diabetes Management for Primary Healthcare Centers.

    Not yet reported University of Abuja 106 participants Est. completion 2026-12-31 2 sites Stand-alone
    Type 2 diabetes
    View official trial listing →
  • Not yet recruiting NCT NCT07221799

    OER Glibenclamide for Neuropathic Pain in Multiple Sclerosis

    Not yet reported University of Maryland, Baltimore 10 participants Est. completion 2029-09-01 1 site Stand-alone
    Other conditions: Multiple Sclerosis, Neuropathic Pain
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources
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