About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
GC012F
GC012F
- Company
- Gracell Biotechnologies (Shanghai) Co., Ltd.
- Mechanism
- Mechanism not yet reported
- Route
- Injectable
- Recruiting trials
- 16 recruiting
Efficacy results: Not yet reported
16 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Nov 7, 2026
Find a Clinical Trial Near Me
See recruiting studies for GC012F and check eligibility with the study team.
Trial details
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Recruiting NCT NCT05850234
AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)
Not yet reported, Not yet reported AstraZeneca 232 participants Est. completion 2029-01-25 36 sites Stand-aloneOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Recruiting NCT NCT05858684
Dual Target CAR-T Cell Treatment for Refractory Systemic Lupus Erythematosus (SLE) Patients
Not yet reported RenJi Hospital 18 participants Est. completion 2029-06-10 1 site Stand-aloneOther conditions: CAR-T Cell TherapyView official trial listing → -
Recruiting NCT NCT06235229
A Study of GC012F in Patients With Relapsed/Refractory Multiple Myeloma
Not yet reported, Not yet reported Gracell Biotechnologies (Shanghai) Co., Ltd. 110 participants Est. completion 2026-03-02 10 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Recruiting NCT NCT06897930
A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE
Not yet reported, Not yet reported AstraZeneca 150 participants Est. completion 2029-05-01 20 sites Stand-aloneOther conditions: Lupus Erythematosus, SystemicView official trial listing → -
Recruiting NCT NCT07058298
GC012F Injection in the Treatment of Refractory Generalized Myasthenia Gravis(24103)
Not yet reported Daishi Tian 6 participants Est. completion 2027-09-10 1 site Stand-aloneOther conditions: Generalized Myasthenia Gravis (gMG)View official trial listing → -
Recruiting NCT NCT07073547
A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)
Not yet reported AstraZeneca 40 participants Est. completion 2028-05-26 13 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Recruiting NCT NCT07081646
A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.
Not yet reported, Not yet reported Alexion Pharmaceuticals, Inc. 91 participants Est. completion 2031-02-14 18 sites Stand-aloneOther conditions: Relapsed AL Amyloidosis, Refractory AL Amyloidosis, Light Chain Amyloidosis, AmyloidosisView official trial listing → -
Recruiting NCT NCT07086404
GC012F Injection in Refractory Idiopathic Inflammatory Myopathy
Not yet reported Daishi Tian 12 participants Est. completion 2029-09-15 1 site Stand-aloneOther conditions: Idiopathic Inflammatory Myopathy (IIM)View official trial listing → -
Recruiting NCT NCT07224373
An Open-label Study of AZD0120 in Adults With Multiple Sclerosis
Not yet reported AstraZeneca 24 participants Est. completion 2028-12-12 19 sites Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Recruiting NCT NCT07250269
Study of GC012F, CAR-T Therapy Targeting CD19 and BCMA in Chinese Participants With Relapsed or Refractory AL Amyloidosis
Not yet reported Gracell Biotechnologies (Shanghai) Co., Ltd. 12 participants Est. completion 2028-11-24 9 sites Stand-aloneOther conditions: Relapsed/Refractory AL AmyloidosisView official trial listing → -
Recruiting NCT NCT07295847
A Study of AZD0120 in Autoimmune Diseases
Not yet reported, Not yet reported AstraZeneca 27 participants Est. completion 2028-02-22 25 sites Stand-aloneOther conditions: Systemic Sclerosis, Idiopathic Inflammatory Myopathies, Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT07303790
This is an Early Exploratory Study to Assess the Tolerability and Safety of GC012F in Patients With Multiple Sclerosis
Not yet reported Daishi Tian 9 participants Est. completion 2028-12-10 1 site Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Recruiting NCT NCT07350837
CAR-T Therapy Targeting CD19 and BCMA in Highly Sensitized Kidney Transplant Participants
Not yet reported Tongji Hospital 12 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Highly Sensitized Patients Awaiting Kidney TransplantView official trial listing → -
Recruiting NCT NCT07391657
A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)
Not yet reported AstraZeneca 508 participants Est. completion 2030-07-29 143 sites Stand-aloneOther conditions: Relapsed Refractory Multiple MyelomaView official trial listing → -
Recruiting NCT NCT07735637
A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6).
Not yet reported AstraZeneca 750 participants Est. completion 2039-11-17 114 sites Stand-aloneOther conditions: Newly Diagnosed Multiple Myeloma (NDMM)View official trial listing → -
Recruiting NCT NCT07764978
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
Not yet reported AstraZeneca 750 participants Est. completion 2034-05-12 124 sites Stand-aloneOther conditions: Newly Diagnosed Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04236011
BCMA and CD19 Targeted Fast Dual CAR-T for BCMA+ Refractory/Relapsed Multiple Myeloma
Not yet reported Shanghai Changzheng Hospital 15 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04617704
BCMA and CD19 Targeted Fast Dual CART for Chromosomal Abnomalities High-risk BCMA+ Multiple Myeloma
Not yet reported Shanghai Changzheng Hospital 15 participants Est. completion 2022-02-01 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04935580
Study of FasT CAR-T GC012F Injection in High Risk TE NDMM Patients
Not yet reported, Not yet reported Shanghai Changzheng Hospital 20 participants Est. completion 2023-07-01 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT05412329
Study of Dual Targeted CD19/BCMA FASTCART GC012F in Relapsed/ Refractory Multiple Myeloma
Not yet reported Shanghai Changzheng Hospital 9 participants Est. completion 2024-06-01 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT05840107
Study of FasT CAR-T GC012F Injection NDMM Patients
Not yet reported Shanghai Changzheng Hospital 18 participants Est. completion 2025-09-30 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT05846347
Phase I Clinical Study of GC012F Injection in Treatment of Refractory Systemic Lupus Erythematosus
Not yet reported Zhejiang University 15 participants Est. completion 2025-04-19 1 site Stand-aloneOther conditions: CAR-TView official trial listing → -
Withdrawn NCT NCT06419166
An Exploratory Clinical Study of GC012F Injection for Refractory gMG
Not yet reported Zhejiang University Est. completion 2027-10-01 1 site Stand-aloneOther conditions: Refractory Generalized Myasthenia GravisView official trial listing → -
Active, not recruiting NCT NCT06530849
A Study of GC012F Injection in Subjects With Refractory Systemic Lupus Erythematosus
Not yet reported, Not yet reported Gracell Biotechnologies (Shanghai) Co., Ltd. 20 participants Est. completion 2027-02-01 2 sites Stand-aloneOther conditions: Refractory Systemic Lupus ErythematosusView official trial listing → -
Not yet recruiting NCT NCT06759948
An Early Exploratory Clinical Study of GC012F Injection in the Treatment of Refractory Generalized Myasthenia Gravis
Not yet reported Chongbo Zhao 18 participants Est. completion 2027-09-10 1 site Stand-aloneOther conditions: Generalized Myasthenia Gravis (gMG)View official trial listing → -
Not yet recruiting NCT NCT07072884
GC012F in Patients With Autoimmune Diseases
Not yet reported Qiong Fu 15 participants Est. completion 2029-03-31 Stand-aloneOther conditions: Systemic Sclerosis (SSc), Idiopathic Inflammatory Myopathy (IIM)View official trial listing → -
Withdrawn NCT NCT07315503
An Open-label Study of GC012F in Rheumatoid Arthritis.
Not yet reported Institute of Hematology & Blood Diseases Hospital, China Est. completion 2041-01-15 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Withdrawn NCT NCT07364487
This is an Open-Label Study to Assess the Safety and Efficacy of GC012F in Patients With Multiple Sclerosis
Not yet reported Huashan Hospital Est. completion 2026-03-25 1 site Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Not yet recruiting NCT NCT07790575
Autoimmune Cytopenia Elimination by Chimeric Antigen Receptor T-cell Therapy
Not yet reported Saurabh Dahiya 16 participants Est. completion 2041-07 1 site Stand-aloneOther conditions: CytopeniaView official trial listing → -
Not yet recruiting NCT NCT07833046
Long-term Follow-up Study in Subjects With Multiple Myeloma Previously Treated With GC012F Injection
RenJi Hospital 40 participants Est. completion 2039-08-21 1 siteOther conditions: Multiple MyelomaView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: GC012F, GC012F Injection, AZD0120
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
