About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Fludarabine Phosphate
- Company
- St. Jude Children's Research Hospital
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 546 recruiting
Efficacy results: Not yet reported
546 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 7, 2026
Find a Clinical Trial Near Me
See recruiting studies for Fludarabine Phosphate and check eligibility with the study team.
Trial details
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Recruiting NCT NCT00801489
Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Not yet reported M.D. Anderson Cancer Center 270 participants Est. completion 2028-10-11 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11, Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11, Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1, de Novo Myelodysplastic Syndrome, High Risk Myelodysplastic Syndrome, Inv(16), Myelodysplastic Syndrome With Excess Blasts, t(16;16), t(8;21), Untreated Adult Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT00920972
Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases
Not yet reported, Not yet reported Washington University School of Medicine 220 participants Est. completion 2031-12 28 sites Stand-aloneOther conditions: Metabolic Disorders, Hematologic, Immune, or Bone Marrow Disorders, Hemoglobinopathies, Non-malignant DisordersView official trial listing → -
Recruiting NCT NCT01174121
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
Not yet reported National Cancer Institute (NCI) 332 participants Est. completion 2029-12-27 1 site Stand-aloneOther conditions: Metastatic Colorectal Cancer, Metastatic Pancreatic Cancer, Metastatic Ovarian Cancer, Metastatic Breast Carcinoma, Metastatic Endocrine Tumors/ Neuroendocrine TumorsView official trial listing → -
Recruiting NCT NCT01666080
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
Not yet reported Masonic Cancer Center, University of Minnesota 30 participants Est. completion 2028-06 1 siteOther conditions: Hematologic Disorders, Hemoglobinopathies, ImmunodeficienciesView official trial listing → -
Recruiting NCT NCT01804634
Reduced Intensity Haploidentical BMT for High Risk Solid Tumors
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 60 participants Est. completion 2030-01 3 sites Stand-aloneOther conditions: Refractory and/or Relapsed Metastatic Solid TumorsView official trial listing → -
Recruiting NCT NCT01861106
Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations
Not yet reported National Cancer Institute (NCI) 144 participants Est. completion 2028-12-31 1 siteOther conditions: GATA2, Immunodeficiency, MDSView official trial listing → -
Recruiting NCT NCT01949129
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
Not yet reported, Not yet reported St. Anna Kinderkrebsforschung 1800 participants Est. completion 2030-06-01 119 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukaemiaView official trial listing → -
Recruiting NCT NCT01962415
Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT
Not yet reported Paul Szabolcs 100 participants Est. completion 2027-11 1 site Stand-aloneOther conditions: Primary Immunodeficiency (PID), Congenital Bone Marrow Failure Syndromes, Inherited Metabolic Disorders (IMD), Hereditary Anemias, Inflammatory Conditions, Systemic Juvenile Idiopathic Arthritis (sJIA), Juvenile Rheumatoid Arthritis (JRA)View official trial listing → -
Recruiting NCT NCT02133196
T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer
Not yet reported National Cancer Institute (NCI) 85 participants Est. completion 2027-10-23 1 site Stand-aloneOther conditions: Advanced Non-Small Cell Lung Cancer, Squamous Cell Carcinoma, Advanced NSCLC, Adenosquamous Carcinoma, AdenocarcinomaView official trial listing → -
Recruiting NCT NCT02143830
HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy
Not yet reported Children's Hospital Medical Center, Cincinnati 70 participants Est. completion 2028-12 3 sites Stand-aloneOther conditions: Fanconi Anemia, Severe Marrow Failure, Myelodysplastic Syndrome (MDS), Acute Myelogenous Leukemia (AML)View official trial listing → -
Recruiting NCT NCT02161783
Treatment of Graft Failure After Hematopoietic Stem Cell Transplantation
Masonic Cancer Center, University of Minnesota 50 participants Est. completion 2032-01-30 1 siteOther conditions: Primary Graft Failure, Secondary Graft FailureView official trial listing → -
Recruiting NCT NCT02443831
CARPALL: Immunotherapy With CD19+CD22 CAR T-cells for CD19+ and CD22+ Acute Lymphoblastic Leukaemia
Not yet reported University College, London 50 participants Est. completion 2041-12-31 3 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT02508038
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
Not yet reported University of Wisconsin, Madison 22 participants Est. completion 2027-12 1 site Stand-aloneObstructive sleep apnea Other conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Myelodysplastic Syndrome, Myeloproliferative Syndrome, Ewing Sarcoma, Primitive Neuroectodermal Tumor, NeuroblastomaView official trial listing → -
Recruiting NCT NCT02621021
A Phase 2 Trial for Metastatic Melanoma Using Adoptive Cell Therapy With Tumor Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of Pembrolizumab
Not yet reported National Cancer Institute (NCI) 53 participants Est. completion 2029-06-16 1 site Stand-aloneOther conditions: MelanomaView official trial listing → -
Recruiting NCT NCT02727803
Personalized NK Cell Therapy in CBT
Not yet reported M.D. Anderson Cancer Center 100 participants Est. completion 2027-05-31 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia With Myelodysplasia-Related Changes, Acute Myeloid Leukemia With Variant MLL Translocations, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Chemotherapy-Related Leukemia, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, ISS Stage II Plasma Cell Myeloma, ISS Stage III Plasma Cell Myeloma, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts, Myelodysplastic Syndrome With Gene Mutation, Myelodysplastic/Myeloproliferative Neoplasm, Previously Treated Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Hodgkin Lymphoma, Recurrent Non-Hodgkin Lymphoma, Refractory Acute Lymphoblastic Leukemia, Refractory Adult Acute Lymphoblastic Leukemia, Secondary Acute Myeloid Leukemia, Therapy-Related Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT02828592
Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia
Not yet reported Northside Hospital, Inc. 20 participants Est. completion 2028-08-31 2 sites Stand-aloneOther conditions: Severe Aplastic AnemiaView official trial listing → -
Recruiting NCT NCT02830724
Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers
Not yet reported, Not yet reported National Cancer Institute (NCI) 124 participants Est. completion 2030-01-01 1 site Stand-aloneOther conditions: Pancreatic Cancer, Renal Cell Cancer, Breast Cancer, Melanoma, Ovarian CancerView official trial listing → -
Recruiting NCT NCT02859402
Allogeneic Stem Cell Transplantation in Relapsed/Refractory T-, NK/T-cell Lymphomas
Not yet reported Keimyung University Dongsan Medical Center 34 participants Est. completion 2027-12 2 sites Stand-aloneOther conditions: T-cell Non-Hodgkin Lymphoma, Lymphoma, Extranodal NK-T-CellView official trial listing → -
Recruiting NCT NCT02917083
CD30 CAR T Cells, Relapsed CD30 Expressing Lymphoma (RELY-30)
Not yet reported Baylor College of Medicine 60 participants Est. completion 2040-02 2 sites Stand-aloneOther conditions: Hodgkin's Lymphoma, Non-Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT03016806
Umbilical Cord Blood Transplantation From Unrelated Donors
University of Rochester 30 participants Est. completion 2027-06 1 siteOther conditions: Acute Leukemia, Immune Deficiency Disorder, Congenital Hematological Disorder, Metabolism Disorder, Aplastic Anemia, Myelodysplastic Syndromes, Chronic Leukemia, Lymphoma, Multiple Myeloma, Solid TumorView official trial listing → -
Recruiting NCT NCT03121001
Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease
Not yet reported University of Illinois at Chicago 50 participants Est. completion 2029-05 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Recruiting NCT NCT03128034
211^At-BC8-B10 Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, or Mixed-Phenotype Acute Leukemia
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 75 participants Est. completion 2029-03-31 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome With Excess Blasts, Recurrent Acute Myeloid Leukemia, Refractory Acute Lymphoblastic Leukemia, Recurrent Acute Lymphoblastic Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Refractory Acute Myeloid Leukemia, Refractory Mixed Phenotype Acute Leukemia, Mixed Phenotype Acute LeukemiaView official trial listing → -
Recruiting NCT NCT03128996
Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders
Not yet reported, Not yet reported Washington University School of Medicine 29 participants Est. completion 2033-04 4 sites Stand-aloneOther conditions: Severe Sickle Cell Disease, Bone Marrow Failure Syndromes, Metabolic Disorders, Immunologic Disorders, Hemoglobinopathies, Non-malignant DisordersView official trial listing → -
Recruiting NCT NCT03190941
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients
Not yet reported, Not yet reported National Cancer Institute (NCI) 110 participants Est. completion 2028-06-29 1 site Stand-aloneOther conditions: Pancreatic Cancer, Gastric Cancer, Gastrointestinal Cancer, Colon Cancer, Rectal CancerView official trial listing → -
Recruiting NCT NCT03196414
Study of T Cells Targeting CD138/BCMA/CD19/More Antigens (CART-138/BCMA/19/More) for Chemotherapy Refractory and Relapsed Multiple Myeloma
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 10 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Recruiting NCT NCT03214562
Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 116 participants Est. completion 2027-09-30 1 site Stand-aloneOther conditions: High Risk Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT03326921
HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant
Not yet reported Fred Hutchinson Cancer Center 24 participants Est. completion 2028-07-16 1 site Stand-aloneOther conditions: Juvenile Myelomonocytic Leukemia, Recurrent Acute Biphenotypic Leukemia, Recurrent Acute Undifferentiated Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Refractory Acute Lymphoblastic Leukemia, Refractory Adult Acute Lymphoblastic Leukemia, Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive, Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm, Recurrent Myelodysplastic Syndrome, Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm, Refractory Myelodysplastic Syndrome, Acute Undifferentiated Leukemia, Mixed Phenotype Acute Leukemia, Recurrent Chronic Myeloid Leukemia, BCR-ABL1 Positive, Refractory Chronic Myeloid Leukemia, BCR-ABL1 Positive, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Acute Biphenotypic Leukemia, Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Minimal Residual Disease, Recurrent Chronic Myelomonocytic Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Leukemia, Chronic Myeloid Leukemia, BCR-ABL1 PositiveView official trial listing → -
Recruiting NCT NCT03412877
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer
Not yet reported National Cancer Institute (NCI) 285 participants Est. completion 2029-03-23 1 site Stand-aloneOther conditions: Endocrine Tumors, Non-Small Cell Lung Cancer, Ovarian Cancer, Breast Cancer, Gastrointestinal/Genitourinary Cancers, Neuroendocrine Tumors, Multiple MyelomaView official trial listing → -
Recruiting NCT NCT03500731
Lung and Bone Marrow Transplantation for Lung and Bone Marrow Failure
Not yet reported, Not yet reported Paul Szabolcs 8 participants Est. completion 2028-12 2 sites Stand-aloneOther conditions: Idiopathic Pulmonary Fibrosis, Emphysema or COPDView official trial listing → -
Recruiting NCT NCT03509961
The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL
Not yet reported Pediatric Transplantation & Cellular Therapy Consortium 95 participants Est. completion 2026-07-01 24 sitesOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT03579875
Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders
Not yet reported Masonic Cancer Center, University of Minnesota 48 participants Est. completion 2029-01-05 1 site Stand-aloneOther conditions: Fanconi Anemia, Severe Aplastic Anemia, Myelodysplastic Syndromes, T Cell Receptor Alpha/Beta Depletion, Telomere Biology Disorder, Bone Marrow Failure, Dyskeratosis Congenita, Telomere Biology DisordersView official trial listing → -
Recruiting NCT NCT03643276
Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017
Not yet reported Martin Schrappe 5000 participants Est. completion 2028-07-14 115 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, PediatricView official trial listing → -
Recruiting NCT NCT03653338
T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias
Not yet reported, Not yet reported Paul Szabolcs 5 participants Est. completion 2028-08-01 1 site Stand-aloneOther conditions: Sickle Cell Anemia, Beta-thalassemia Major, Diamond-blackfan AnemiaView official trial listing → -
Recruiting NCT NCT03666000
Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)
Not yet reported Imugene Limited 135 participants Est. completion 2027-06 15 sites Stand-aloneOther conditions: Non-Hodgkin Lymphoma, B-cell Acute Lymphoblastic Leukemia, Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT03670966
211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 30 participants Est. completion 2029-10-20 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Acute Myeloid Leukemia in Remission, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome With Excess Blasts, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Refractory Mixed Phenotype Acute Leukemia, Hematopoietic and Lymphoid Cell NeoplasmView official trial listing → -
Recruiting NCT NCT03676504
Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR
Not yet reported, Not yet reported University Hospital Heidelberg 68 participants Est. completion 2027-12-31 2 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult, Acute Lymphoblastic Leukemia, Pediatric, Chronic Lymphocytic Leukemia, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, Mantle Cell LymphomaView official trial listing → -
Recruiting NCT NCT03721068
Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma
Not yet reported UNC Lineberger Comprehensive Cancer Center 18 participants Est. completion 2044-06-19 2 sites Stand-aloneObstructive sleep apnea Other conditions: NeuroblastomaView official trial listing → -
Recruiting NCT NCT03765177
CLIC-1901 for the Treatment of Patients With Relapsed/Refractory CD19 Positive Hematologic Malignancies
Not yet reported, Not yet reported Ottawa Hospital Research Institute 60 participants Est. completion 2042-06-30 3 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Non-Hodgkin's Lymphoma, Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT03852407
Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity Conditioning
Not yet reported University of Liege 114 participants Est. completion 2038-11-01 10 sites Stand-aloneOther conditions: Acute Myeloid Leukemia in Remission, Myelodysplastic Syndromes, Chronic Myeloid Leukemia in Remission, Myeloproliferative Syndrome, Myeloproliferative Disorder, Acute Lymphoid Leukemia in Remission, Multiple Myeloma, Chronic Lymphoid Leukemia, Non Hodgkin Lymphoma, Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT03937544
Intravenous Autologous CD19 CAR-T Cells for R/R B-ALL
Not yet reported, Not yet reported National University of Malaysia 10 participants Est. completion 2027-03-18 1 site Stand-aloneOther conditions: Relapsed B Acute Lymphoblastic Leukaemia, Refractory B Acute Lymphoblastic LeukaemiaView official trial listing → -
Recruiting NCT NCT03938987
Anti-CD19, Dual Co-stimulatory (4-1BB, CD3ζ) Chimeric Antigen Receptor T-cells in Patients With Relapsed/Refractory Aggressive Lymphoma or Acute Lymphoblastic Leukemia (ALL)
Not yet reported, Not yet reported University of Alberta 63 participants Est. completion 2027-12 6 sites Stand-aloneOther conditions: Relapsed Non Hodgkin Lymphoma, Relapsed Adult ALL, Relapsed Pediatric ALLView official trial listing → -
Recruiting NCT NCT03964506
Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant
Not yet reported Omar Aljitawi 24 participants Est. completion 2028-03-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, Atypical Chronic Myeloid Leukemia, Chronic Monocytic Leukemia, Myelofibrosis, Myelodysplastic/Myeloproliferative NeoplasmView official trial listing → -
Recruiting NCT NCT03970096
Graft Versus Host Disease-Reduction Strategies for Donor Blood Stem Cell Transplant Patients With Acute Leukemia or Myelodysplastic Syndrome (MDS)
Not yet reported Fred Hutchinson Cancer Center 120 participants Est. completion 2029-12-31 3 sites Stand-aloneOther conditions: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative NeoplasmView official trial listing → -
Recruiting NCT NCT03980002
A Prospective Multicenter Phase 2 Study of FCR/BR Alternating With Ibrutinib in Treatment-naive Patients With CLL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 50 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT03980769
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Thiotepa in Treating Patients With Non-malignant Disorders
Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2028-07-01 1 site Stand-aloneOther conditions: Non-Neoplastic Hematopoietic and Lymphoid Cell DisorderView official trial listing → -
Recruiting NCT NCT04022239
Bendamustine With or Without Cyclophosphamide in Preventing GVHD in Patients Undergoing Stem Cell Transplant
Not yet reported, Not yet reported M.D. Anderson Cancer Center 25 participants Est. completion 2027-07-31 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid System NeoplasmView official trial listing → -
Recruiting NCT NCT04024761
A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation
Not yet reported Dana-Farber Cancer Institute 50 participants Est. completion 2026-12-01 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Myeloproliferative Neoplasm, Juvenile Myelomonocytic LeukemiaView official trial listing → -
Recruiting NCT NCT04083183
Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant Diseases
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2028-01-09 1 site Stand-aloneOther conditions: Non-Malignant NeoplasmView official trial listing → -
Recruiting NCT NCT04083495
CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma
Not yet reported UNC Lineberger Comprehensive Cancer Center 20 participants Est. completion 2038-08 2 sites Stand-aloneOther conditions: Peripheral T Cell LymphomaView official trial listing → -
Recruiting NCT NCT04146298
Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer
Not yet reported, Not yet reported Changhai Hospital 30 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Pancreatic Cancer, Pancreatic Neoplasms, Pancreatic Ductal Adenocarcinoma, Advanced CancerView official trial listing → -
Recruiting NCT NCT04167696
Study in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02
Not yet reported Celyad Oncology SA 27 participants Est. completion 2035-02 5 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT04187105
BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)
Not yet reported University of Illinois at Chicago 27 participants Est. completion 2026-12 1 siteOther conditions: Acute Leukemia, MDSView official trial listing → -
Recruiting NCT NCT04195633
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies
Not yet reported Fred Hutchinson Cancer Center 60 participants Est. completion 2029-03-12 1 site Stand-aloneOther conditions: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Adult Diffuse Large Cell Lymphoma, Anaplastic Large Cell Lymphoma, Burkitt Lymphoma, Chronic Myeloid Leukemia, BCR-ABL1 Positive, Chronic Myelomonocytic Leukemia, Hodgkin Lymphoma, Lymphoblastic Lymphoma, Lymphoplasmacytic Lymphoma, Mantle Cell Lymphoma, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome, Prolymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, Refractory Follicular Lymphoma, Refractory Marginal Zone Lymphoma, Refractory Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT04196413
GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG)
Not yet reported Stanford University 97 participants Est. completion 2043-07-31 1 site Stand-aloneOther conditions: Glioma of Spinal Cord, Glioma of BrainstemView official trial listing → -
Recruiting NCT NCT04223765
Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
Not yet reported UNC Lineberger Comprehensive Cancer Center 20 participants Est. completion 2043-03-22 1 site Stand-aloneObstructive sleep apnea Other conditions: Mantle Cell Lymphoma, Follicular Lymphoma, Splenic Marginal Zone Lymphoma, Nodal Marginal Zone Lymphoma, Indolent Non-hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT04224558
Stem Cell Transplantation in Crohn's Disease
Not yet reported, Not yet reported Cedars-Sinai Medical Center 15 participants Est. completion 2027-09-30 1 site Stand-aloneOther conditions: Crohn DiseaseView official trial listing → -
Recruiting NCT NCT04232085
Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Marrow Failures
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 27 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Primary Immune Deficiency Disorder, Immune Deficiency Disease, Bone Marrow Failure, Short Telomere Length, Fanconi Anemia, Non Fanconi DNA-DSB Repair Disorder, Hoyeraal-Hreidarsson Syndrome, Dyskeratosis Congenita, Telomere Biology Disorder, Short Telomere SyndromeView official trial listing → -
Recruiting NCT NCT04282044
Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies
Not yet reported BioEclipse Therapeutics 60 participants Est. completion 2026-10 3 sites Stand-aloneObstructive sleep apnea Other conditions: Solid Tumor, Adult, Triple Negative Breast Cancer, Colorectal Cancer, Hepatocellular Carcinoma, Epithelial Ovarian Cancer, Gastric Cancer, Non-small Cell Lung Cancer, Malignant MelanomaView official trial listing → -
Recruiting NCT NCT04314219
Comparing Post-Transplant Cyclophosphamide As GVHD Prophylaxis to Standard of Care for Acute Leukemia Patients
Not yet reported King Faisal Specialist Hospital & Research Center 264 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL) in Complete Remission, Acute Myeloid Leukemia (AML) in RemissionView official trial listing → -
Recruiting NCT NCT04318678
CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)
Not yet reported St. Jude Children's Research Hospital 108 participants Est. completion 2030-07-29 2 sites Stand-aloneOther conditions: AML/MDS, B-ALL, T-ALL, BPDCNView official trial listing → -
Recruiting NCT NCT04339777
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Inborn Errors of Immunity
Not yet reported National Cancer Institute (NCI) 66 participants Est. completion 2027-11-30 1 siteOther conditions: Lymphoproliferative Disorders, Autoimmune Lymphoproliferative, Immune System Diseases, Common Variable Immunodeficiency, Primary T-cell Immunodeficiency DisordersView official trial listing → -
Recruiting NCT NCT04370301
Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis
Not yet reported Fred Hutchinson Cancer Center 20 participants Est. completion 2029-08-31 1 site Stand-aloneOther conditions: Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Recruiting NCT NCT04422912
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)
Not yet reported, Not yet reported Cabaletta Bio 40 participants Est. completion 2029-01 13 sites Stand-aloneOther conditions: Pemphigus VulgarisView official trial listing → -
Recruiting NCT NCT04440436
Assessment of Safety and Efficacy of IM19 for Recurrent or Refractory (R/R) Non-Hodgkin's Lymphoma(NHL) Patients
Not yet reported, Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 52 participants Est. completion 2035-06-04 1 site Stand-aloneOther conditions: NHLView official trial listing → -
Recruiting NCT NCT04510051
CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in Children
Not yet reported City of Hope Medical Center 18 participants Est. completion 2027-02-24 3 sites Stand-aloneOther conditions: Malignant Brain Neoplasm, Recurrent Malignant Brain Neoplasm, Refractory Malignant Brain NeoplasmView official trial listing → -
Recruiting NCT NCT04545762
Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma
Not yet reported C. Babis Andreadis 36 participants Est. completion 2026-10-31 1 site Stand-aloneOther conditions: Refractory Non-Hodgkin Lymphoma, Burkitt Lymphoma, Mantle Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Primary Mediastinal Large B Cell Lymphoma, Diffuse Large B Cell Lymphoma, Small Lymphocytic Lymphoma, Transformed Lymphoma, Non-Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT04558736
Haploidentical HCT for Severe Aplastic Anemia
Not yet reported St. Jude Children's Research Hospital 21 participants Est. completion 2030-07-01 1 site Stand-aloneOther conditions: Aplastic Anemia, Bone Marrow Failure SyndromeView official trial listing → -
Recruiting NCT NCT04561557
Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System
Not yet reported Tongji Hospital 36 participants Est. completion 2027-05-31 1 site Stand-aloneOther conditions: Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Neuromyelitis Optica Spectrum Disorder, Myasthenia Gravis, Chronic Inflammatory Demyelinating Polyradiculoneuropathy, Idiopathic Inflammatory Myopathies, Multiple Sclerosis, Autoimmune Encephalitis, Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD), POEMS SyndromeView official trial listing → -
Recruiting NCT NCT04586478
Phase II Clinical Trial of CNCT19 Cell Injection in the Treatment of Relapsed or Refractory Non-Hodgkin's Lymphoma
Not yet reported Juventas Cell Therapy Ltd. 60 participants Est. completion 2025-09-30 17 sites Stand-aloneOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Recruiting NCT NCT04614103
Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer
Not yet reported Iovance Biotherapeutics, Inc. 170 participants Est. completion 2031-12 71 sites Stand-aloneOther conditions: Metastatic Non Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT04644016
Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant Disorders
Not yet reported Memorial Sloan Kettering Cancer Center 31 participants Est. completion 2026-12-20 1 site Stand-aloneOther conditions: AML, ALL, MDS, MPD Withou Myelofibrosis, NHL or HL, Inherited Metabolic Disorders, Hemoglobinopathies, Bone Marrow Failure, HLHView official trial listing → -
Recruiting NCT NCT04678401
IS-free Treg HaploHCT
Not yet reported Dana-Farber Cancer Institute 30 participants Est. completion 2029-08-31 1 site Stand-aloneOther conditions: Stem Cell Transplant Complications, Graft Vs Host Disease, Myeloid Leukemia, Acute, Myeloid Leukemia in Relapse (Disorder), Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT04684147
Clinical Trial of CNCT19 Cell Injection in the Treatment of Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported Juventas Cell Therapy Ltd. 100 participants Est. completion 2026-12-31 11 sites Stand-aloneOther conditions: Relapsed or Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT04708054
Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDS
Not yet reported, Not yet reported M.D. Anderson Cancer Center 324 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT04784052
Depleted Donor Stem Cell Transplant in Children and Adults With Fanconi Anemia After Being Conditioned With a Regimen Containing Briquilimab
Not yet reported, Not yet reported Porteus, Matthew, MD 18 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Fanconi AnemiaView official trial listing → -
Recruiting NCT NCT04792489
DALY II USA/ MB-CART2019.1 for DLBCL
Not yet reported Miltenyi Biomedicine GmbH 315 participants Est. completion 2028-12-31 32 sites Stand-aloneOther conditions: Refractory Diffuse Large B Cell Lymphoma (DLBCL), Relapsed Diffuse Large B Cell Lymphoma, High Grade B-cell Lymphoma (HGBCL), Primary Mediastinal B-cell Lymphoma (PMBCL), Transformed Lymphoma, Central Nervous System Lymphoma, Mantle Cell Lymphoma (MCL), Richter Transformation, Transplant-ineligible 2nd Line DLBCLView official trial listing → -
Recruiting NCT NCT04815356
Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients With Relapsed/Refractory Hairy Cell Leukemia and Variant
Not yet reported National Cancer Institute (NCI) 27 participants Est. completion 2036-12-01 1 site Stand-aloneOther conditions: Hairy Cell Leukemia, Hairy Cell Leukemia VariantView official trial listing → -
Recruiting NCT NCT04848064
Third-Party Natural Killer Cells and Mogamulizumab for the Treatment of Relapsed or Refractory Cutaneous T-cell Lymphomas or Adult T-Cell Leukemia/Lymphoma
Not yet reported John Reneau 12 participants Est. completion 2027-01-30 1 site Stand-aloneOther conditions: Recurrent Adult T-Cell Leukemia/Lymphoma, Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma, Refractory Adult T-Cell Leukemia/Lymphoma, Refractory Primary Cutaneous T-Cell Non-Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT04881240
Study of CD19 Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia
Not yet reported St. Jude Children's Research Hospital 60 participants Est. completion 2028-07-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia, Refractory, Pediatric ALLView official trial listing → -
Recruiting NCT NCT04892277
CD19-Directed CAR-T Cell Therapy for the Treatment of Relapsed/Refractory B Cell Malignancies
Not yet reported Mayo Clinic 25 participants Est. completion 2040-03-27 1 site Stand-aloneOther conditions: Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Chronic Lymphocytic Leukemia, Recurrent Small Lymphocytic Lymphoma, Recurrent Transformed Chronic Lymphocytic Leukemia, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Small Lymphocytic Lymphoma, Refractory Transformed Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT04897321
B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)
Not yet reported St. Jude Children's Research Hospital 48 participants Est. completion 2028-03-01 1 siteObstructive sleep apnea Other conditions: Pediatric Solid Tumor, Neuroblastoma, Ewing Sarcoma, Wilms Tumor, Adrenocortical Cancer, Desmoplastic Small Round Cell Tumor, Germ Cell Cancer, Rhabdoid Tumor, Clear Cell Sarcoma, Hepatoblastoma, Melanoma, Carcinoma, Malignant Peripheral Nerve Sheath Tumors, Soft Tissue SarcomaView official trial listing → -
Recruiting NCT NCT04959175
Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies
Not yet reported, Not yet reported National Cancer Institute (NCI) 320 participants Est. completion 2027-04-30 2 sites Stand-aloneOther conditions: Hematologic NeoplasmsView official trial listing → -
Recruiting NCT NCT04989803
Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma
Not yet reported, Not yet reported Kite, A Gilead Company 247 participants Est. completion 2030-02 34 sites Stand-aloneOther conditions: Relapsed and/or Refractory B-cell LymphomaView official trial listing → -
Recruiting NCT NCT05003895
GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor Malignancies
Not yet reported National Cancer Institute (NCI) 38 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma, Hepatocellular Cancer, Metastatic Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05010564
Trivalent CAR-T Cell in Acute B-Lineage Leukemia (TRICAR-ALL)
Not yet reported Baylor College of Medicine 38 participants Est. completion 2040-03-29 1 site Stand-aloneOther conditions: Leukemia, B-CellView official trial listing → -
Recruiting NCT NCT05027945
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Not yet reported National Cancer Institute (NCI) 54 participants Est. completion 2031-07-01 1 site Stand-aloneOther conditions: Immunodeficiency, Hematopoietic Stem Cell TransplantationView official trial listing → -
Recruiting NCT NCT05031897
Two Step Haplo With Radiation Conditioning
Not yet reported Thomas Jefferson University 63 participants Est. completion 2032-04 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Adult T-Cell Leukemia/Lymphoma, Aplastic Anemia, Chronic Lymphocytic Leukemia, Chronic Myeloid Leukemia, BCR-ABL1 Positive, Chronic Myelomonocytic Leukemia, Essential Thrombocythemia, Hematopoietic and Lymphatic System Neoplasm, Hodgkin Lymphoma, Multiple Myeloma, Myelodysplastic Syndrome, Myelofibrosis, Myeloid Neoplasm, Non-Hodgkin Lymphoma, Polycythemia Vera, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT05052528
Fludarabine and Cyclophosphamide With or Without Rituximab Before CD19 Chimeric Antigen Receptor T Cells for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Not yet reported University of California, Davis 36 participants Est. completion 2027-12-15 1 site Stand-aloneOther conditions: Recurrent Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell LymphomaView official trial listing → -
Recruiting NCT NCT05077527
Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma
Not yet reported AIDS Malignancy Consortium 20 participants Est. completion 2029-01-31 7 sites Stand-aloneOther conditions: AIDS-Related Diffuse Large B-cell Lymphoma, AIDS-Related Non-Hodgkin Lymphoma, HIV Infection, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Grade 3b Follicular Lymphoma, Recurrent High Grade B-Cell Lymphoma, Recurrent Non-Hodgkin Lymphoma, Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Recurrent Transformed B-Cell Non-Hodgkin Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Grade 3b Follicular Lymphoma, Refractory High Grade B-Cell Lymphoma, Refractory Non-Hodgkin Lymphoma, Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Refractory Transformed B-Cell Non-Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT05092451
Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances
Not yet reported, Not yet reported M.D. Anderson Cancer Center 80 participants Est. completion 2030-08-31 1 site Stand-aloneOther conditions: B-Cell Lymphoma, Myelodysplastic Syndromes (MDS), Acute Myeloid Leukemia (AML), Multiple Myeloma, Plasma Cell Leukemia, Hodgkin Lymphoma, T-cell Non-Hodgkin's Lymphoma/ T-cell Acute Lymphoblastic Leukmeia, Myelodysplastic Syndrome / Chronic Myelomonocytic Leukemia, Blastic Transformation of Chronic Myeloid Leukemia, Germ Cell TumorsView official trial listing → -
Recruiting NCT NCT05110742
Phase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological Malignances
Not yet reported, Not yet reported M.D. Anderson Cancer Center 64 participants Est. completion 2030-12-31 1 site Stand-aloneOther conditions: Hematological MalignancyView official trial listing → -
Recruiting NCT NCT05126849
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Post-transplant Cyclophosphamide in Patients With Acquired Refractory Aplastic Anemia or in Relapse After Immunosuppression
Not yet reported Assistance Publique - Hôpitaux de Paris 31 participants Est. completion 2027-01-06 35 sites Stand-aloneOther conditions: Refractory Idiopathic Aplastic Anemia, Haploidentical Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Recruiting NCT NCT05141474
Assessment of the Safety and Tolerability of ex Vivo Next-generation Neoantigen-selected Tumor-infiltrating Lymphocyte (TIL) Therapy in Advanced Epithelial Tumors and Immune Checkpoint Blockade (ICB) Resistant Solid Tumors
Not yet reported Vall d'Hebron Institute of Oncology 10 participants Est. completion 2027-01-01 1 site Stand-aloneOther conditions: Epithelial Tumors, Malignant, Malignant Solid TumorView official trial listing → -
Recruiting NCT NCT05183035
Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)
Not yet reported PedAL BCU, LLC 130 participants Est. completion 2031-04 90 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05225363
Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian Cancer
Not yet reported City of Hope Medical Center 33 participants Est. completion 2028-11-05 1 site Stand-aloneOther conditions: Platinum-Resistant Ovarian CarcinomaView official trial listing → -
Recruiting NCT NCT05238792
Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors
Not yet reported Children's National Research Institute 24 participants Est. completion 2029-10 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Recruiting NCT NCT05290662
Registry of Patients Having Received oNKord®
Glycostem Therapeutics BV 50 participants Est. completion 2028-03 2 sitesOther conditions: AMLView official trial listing → -
Recruiting NCT NCT05310591
Combination of an Anti-PD1 Antibody With Tisagenlecleucel Reinfusion in Children, Adolescents and Young Adults With Acute Lymphoblastic Leukemia After Loss of Persistence
Not yet reported, Not yet reported Assistance Publique - Hôpitaux de Paris 26 participants Est. completion 2027-03 13 sites Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia, in RelapseView official trial listing → -
Recruiting NCT NCT05317403
Venetoclax to Augment Epigenetic Modification and Chemotherapy
Not yet reported Medical College of Wisconsin 40 participants Est. completion 2027-01 1 siteOther conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia RefractoryView official trial listing → -
Recruiting NCT NCT05323201
Study Of B7H3 CAR-T Cells in Treating Advanced Liver Cancer
Not yet reported, Not yet reported The Affiliated Hospital of Xuzhou Medical University 15 participants Est. completion 2027-02-10 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05326243
Phase 1/2 Study of CD19 Chimeric Antigen Receptor T-cell (CD19 CAR-T; PL001) for Relapsed or Refractory B-cell Lymphoma
Not yet reported, Not yet reported Pell Bio-Med Technology Co., Ltd. 49 participants Est. completion 2027-03-31 5 sites Stand-aloneOther conditions: Diffuse Large B Cell Lymphoma, Primary Mediastinal Large B Cell Lymphoma, Large B-cell Lymphoma, Follicular Lymphoma Grade 3A, Follicular Lymphoma Grade 3BView official trial listing → -
Recruiting NCT NCT05327023
Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies
Not yet reported, Not yet reported National Cancer Institute (NCI) 430 participants Est. completion 2029-07-02 1 site Stand-aloneOther conditions: Hematologic NeoplasmsView official trial listing → -
Recruiting NCT NCT05334823
A Study of pCAR-19B in the Treatment of CD19-positive Relapsed/Refractory B-ALL in Children and Adolescents
Not yet reported Chongqing Precision Biotech Co., Ltd 100 participants Est. completion 2029-07-01 16 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Relapsed Pediatric ALL, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT05361174
A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer
Not yet reported, Not yet reported Iovance Biotherapeutics, Inc. 53 participants Est. completion 2029-09 11 sites Stand-aloneOther conditions: Unresectable Melanoma, Metastatic Melanoma, Stage III Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT05417971
Reduced Intensity Fludarabine and TBI Prior to Haplo-Identical Transplantation
Northside Hospital, Inc. 20 participants Est. completion 2026-12-31 1 siteOther conditions: Hematologic MalignancyView official trial listing → -
Recruiting NCT NCT05426252
Thal-Fabs: Reduced Toxicity Conditioning for High Risk Thalassemia
Not yet reported, Not yet reported The Hospital for Sick Children 20 participants Est. completion 2026-12-31 1 siteOther conditions: Thalassemia in ChildrenView official trial listing → -
Recruiting NCT NCT05427136
Early Pulmonary Dysfunction in Childhood Cancer Patients
University Children's Hospital Basel 140 participants Est. completion 2051-06 5 sitesOther conditions: Pulmonary DysfunctionView official trial listing → -
Recruiting NCT NCT05436418
The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation
Not yet reported, Not yet reported National Cancer Institute (NCI) 260 participants Est. completion 2028-06-25 2 sites Stand-aloneOther conditions: Peripheral Blood Stem Cell Transplantation, Hematopoietic Stem Cell TransplantationView official trial listing → -
Recruiting NCT NCT05436561
Reduced MBF Regimen for Patients >=55 Years With Myeloid Malignancies
Not yet reported Shanghai Jiao Tong University School of Medicine 61 participants Est. completion 2027-06-30 2 sites Stand-aloneOther conditions: Disease-free SurvivalView official trial listing → -
Recruiting NCT NCT05442515
CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory B Cell Malignancies
Not yet reported, Not yet reported National Cancer Institute (NCI) 130 participants Est. completion 2029-07-01 1 site Stand-aloneOther conditions: B-NHL, B-Non Hodgkin Lymphoma, Acute Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, B-precursor ALL, B-All, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, B Cell, B-Cell Lymphoma, B-Cell Leukemia, Acute Lymphoid LeukemiaView official trial listing → -
Recruiting NCT NCT05445011
Anti-FLT3 CAR-T Cell (TAA05 Cell Injection) in the Treatment of Relapsed / Refractory Acute Myeloid Leukemia
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 12 participants Est. completion 2027-06-14 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05476770
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 54 participants Est. completion 2027-11-11 31 sites Stand-aloneOther conditions: Hematologic Malignancy, AML, ALL, BPDCN, MDS, Lymphoblastic Lymphoma, Lymphoma, B-Cell, Lymphoma, T-Cell, Hodgkin Lymphoma, Mixed Phenotype Acute Leukemia, Acute Undifferentiated LeukemiaView official trial listing → -
Recruiting NCT NCT05477589
Studying Conditioning Regimen In Pediatric Transplantation - AML , SCRIPT-AML
Not yet reported Vastra Gotaland Region 170 participants Est. completion 2031-12-31 17 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML) in Remission, Stem Cell TransplantationView official trial listing → -
Recruiting NCT NCT05483491
KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer
Not yet reported Christian Hinrichs 30 participants Est. completion 2030-12-31 2 sites Stand-aloneOther conditions: Gastric Cancer, Breast Cancer, Cervical Cancer, Lung CancerView official trial listing → -
Recruiting NCT NCT05503134
Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for Relapsed/Refractory AML
Not yet reported, Not yet reported Nationwide Children's Hospital 20 participants Est. completion 2027-02 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05508009
Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same Donor
Not yet reported, Not yet reported Alice Bertaina 12 participants Est. completion 2034-10 1 site Stand-aloneChronic kidney disease Other conditions: SIOD, Cystinosis, FSGS, SLE NephritisView official trial listing → -
Recruiting NCT NCT05518253
A Clinical Study of CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors
Not yet reported Weijia Fang, MD 30 participants Est. completion 2027-05-30 1 site Stand-aloneOther conditions: Metastatic Tumor, Advanced Solid Tumor, Renal Cell Carcinoma, Ovarian Cancer, Cervix CancerView official trial listing → -
Recruiting NCT NCT05554939
Allogenic CD19-targeting CAR-γδT Cell Therapy in R/R NHL
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2027-12-31 2 sites Stand-aloneOther conditions: Non Hodgkin's LymphomaView official trial listing → -
Recruiting NCT NCT05564390
MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)
Not yet reported National Cancer Institute (NCI) 2000 participants Est. completion 2029-05-15 354 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm, Acute Myeloid Leukemia Post Cytotoxic Therapy, Acute Myeloid Leukemia, Myelodysplasia-Related, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT05586074
HEC73543 Versus Salvage Chemotherapy in R/R FLT3-ITD AML
Not yet reported Sunshine Lake Pharma Co., Ltd. 324 participants Est. completion 2028-05-30 1 siteOther conditions: Leukemia, Acute Myeloid (AML)View official trial listing → -
Recruiting NCT NCT05618041
The Safety and Efficay Investigation of CAR-T Cell Therapy for Patients With Hematological Malignancies
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 50 participants Est. completion 2027-12-06 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Lymphoma, Multiple MyelomaView official trial listing → -
Recruiting NCT NCT05618925
Study for Subjects With Relapsed/Refractory Non- Hodgkin Lymphoma
Not yet reported ImmunityBio, Inc. 20 participants Est. completion 2027-03-15 2 sites Stand-aloneOther conditions: Non Hodgkin's Lymphoma Refractory/RelapsedView official trial listing → -
Recruiting NCT NCT05625594
Intracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/Mem T-lymphocytes) for the Treatment of Central Nervous System Lymphoma
Not yet reported City of Hope Medical Center 20 participants Est. completion 2028-05-22 1 site Stand-aloneOther conditions: Central Nervous System LymphomaView official trial listing → -
Recruiting NCT NCT05633615
Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma
Not yet reported SWOG Cancer Research Network 396 participants Est. completion 2030-06-30 87 sites Stand-aloneOther conditions: Diffuse Large B-Cell Lymphoma, Grade 3b Follicular Lymphoma, Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Transformed Follic Lymph to Diff Large B-Cell Lymphoma, Transformed Marg Zone Lymph to Diff Large B-Cell LymphomaView official trial listing → -
Recruiting NCT NCT05639972
E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers
Not yet reported, Not yet reported Christian Hinrichs 15 participants Est. completion 2026-10-01 2 sites Stand-aloneOther conditions: HPV-Associated Cervical Carcinoma, HPV-Related Carcinoma, HPV-Related Malignancy, HPV Positive Oropharyngeal Squamous Cell Carcinoma, HPV-Related Adenocarcinoma, HPV-Related Adenosquamous Carcinoma, HPV-Related Squamous Cell Carcinoma, HPV-Related Anal Squamous Cell Carcinoma, HPV-Related Penile Squamous Cell Carcinoma, HPV-Related Vulvar Squamous Cell Carcinoma, HPV-Related Endocervical Adenocarcinoma, Cervical Cancer, Oropharynx Cancer, Anal Cancer, Vulvar Cancer, Penile Cancer, Vaginal CancerView official trial listing → -
Recruiting NCT NCT05656573
CART-PSMA Cells for Advanced Prostate Cancer
Not yet reported Nova Therapeutics LLC 20 participants Est. completion 2025-12-01 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Recruiting NCT NCT05667506
A Study of CNCT19 Treatment in Children and Adolescent r/r ALL Patients(Pediatric)
Not yet reported, Not yet reported Juventas Cell Therapy Ltd. 47 participants Est. completion 2027-05-30 9 sites Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT05681650
HER2 Targeted HypoSti.CAR-T Cells in HER2 Positive Advanced Solid Tumors
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: HER2 Positive Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT05681780
Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 20 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Non Small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer, Recurrent Non Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT05686226
E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers
Not yet reported Christian Hinrichs 20 participants Est. completion 2027-01-01 3 sites Stand-aloneOther conditions: Cervical Cancer, Throat Cancer, Oropharynx Cancer, Anal Cancer, Vulva Cancer, Vaginal Cancer, Penile Cancer, Metastatic Cancer, HPV-Related Malignancy, HPV-Related Carcinoma, HPV-Related Cervical Carcinoma, HPV-Related Squamous Cell Carcinoma, HPV-Related Adenocarcinoma, HPV Positive Oropharyngeal Squamous Cell Carcinoma, HPV-Associated Vaginal Adenocarcinoma, HPV-Related Adenosquamous Carcinoma, HPV-Related Endocervical Adenocarcinoma, HPV-Related Anal Squamous Cell Carcinoma, HPV-Related Penile Squamous Cell Carcinoma, HPV-Related Vulvar Squamous Cell Carcinoma, HPV Positive Rectal Squamous Cell CarcinomaView official trial listing → -
Recruiting NCT NCT05702853
Metabolically Fit CD19 CAR T-cell Therapy With CD34 Selection in Patients With CD19+ Relapsed/Refractory NHL, CLL/SLL
Not yet reported, Not yet reported Medical University of South Carolina 27 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: B-cell Non Hodgkin Lymphoma, Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT05705570
Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies
Not yet reported Nelson Hamerschlak 30 participants Est. completion 2028-12-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia Refractory, B-cell Lymphoma Recurrent, B-cell Lymphoma Refractory, Chronic Lymphocytic Leukemia Recurrent, Chronic Lymphocytic Leukemia RefractoryView official trial listing → -
Recruiting NCT NCT05722418
CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma
Not yet reported Caribou Biosciences, Inc. 50 participants Est. completion 2027-12 16 sites Stand-aloneOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Recruiting NCT NCT05735717
MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies
Not yet reported Masonic Cancer Center, University of Minnesota 70 participants Est. completion 2030-11-30 1 site Stand-aloneOther conditions: Hematologic Malignancy, Acute Leukemia, Remission, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, AML, TP53, Intrachromosomal Amplification of Chromosome 21, Cytogenetic Abnormality, CNS Leukemia, Minimal Residual Disease, Myelodysplasia, Juvenile Myelomonocytic Leukemia, Somatic Mutation, PTPN11 Gene Mutation, N-RAS Gene Amplification, Neurofibromatosis 1, NF1 Mutation, CBL Gene Mutation, Monosomy 7, Chromosome Abnormality, Fetal Hemoglobin, Lymphoblastic Lymphoma, High Grade Non-Hodgkin's Lymphoma, AdultView official trial listing → -
Recruiting NCT NCT05736419
A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)
Not yet reported Memorial Sloan Kettering Cancer Center 24 participants Est. completion 2027-02-09 6 sites Stand-aloneOther conditions: Sickle Cell Disease, Thalassemia, Beta, ThalassemiaView official trial listing → -
Recruiting NCT NCT05748197
A Study of ADCLEC.syn1 in People With Acute Myeloid Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 40 participants Est. completion 2028-04-18 7 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05768529
Clinical Study of U16 in Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Not yet reported, Not yet reported Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd 100 participants Est. completion 2026-12-31 2 sites Stand-aloneOther conditions: Relapsed or Refractory Non-Hodgkin's LymphomaView official trial listing → -
Recruiting NCT NCT05787574
A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition
Not yet reported Joseph Oved 39 participants Est. completion 2027-03 13 sites Stand-aloneOther conditions: Primary Immune Regulatory Disorder, Autoimmune Lymphoproliferative, Immune System DiseasesView official trial listing → -
Recruiting NCT NCT05805605
Allo HSCT Using RIC and PTCy for Hematological Diseases
Not yet reported Masonic Cancer Center, University of Minnesota 56 participants Est. completion 2028-10-22 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Biphenotypic Acute Leukemia, Undifferentiated Leukemia, Prolymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Myelodysplastic Syndrome With Excess Blasts-1, Burkitt Lymphoma, Relapsed T-Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone Lymphoma, Follicular Lymphoma, Myeloproliferative Neoplasm, MyelofibrosisView official trial listing → -
Recruiting NCT NCT05826535
Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma
Not yet reported, Not yet reported Lyell Immunopharma, Inc. 270 participants Est. completion 2031-06-30 35 sites Stand-aloneOther conditions: Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Large B-cell LymphomaView official trial listing → -
Recruiting NCT NCT05831033
Safety and Efficacy of an Autologous Tumor Infiltrating Lymphocyte (TIL) Therapy in Patients with Advanced Solid Tumors
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 16 participants Est. completion 2027-06-15 3 sites Stand-aloneOther conditions: Solid TumorView official trial listing → -
Recruiting NCT NCT05832515
AHSCT With Fludarabine and Cyclophosphamide Based Conditioning Regimes in Patients With Multiple Sclerosis
Not yet reported St. Petersburg State Pavlov Medical University 200 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Recruiting NCT NCT05849207
Post-Transplant Cyclophosphamide in Patients Aged >/= 65 Years Undergoing Haploidentical Transplant
Not yet reported Ronald Paquette 26 participants Est. completion 2028-07-01 1 siteOther conditions: Hematologic MalignanciesView official trial listing → -
Recruiting NCT NCT05849662
A Phase I/II Study of Trametinib and Azacitidine for Patients With Newly Diagnosed Juvenile Myelomonocytic Leukemia
Not yet reported, Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 58 participants Est. completion 2029-12 21 sites Stand-aloneOther conditions: Leukemia, Juvenile Myelomonocytic, JMML, JCML, Neurofibromatosis 1, CBL SyndromeView official trial listing → -
Recruiting NCT NCT05870995
Chemotherapy CLAGE-Ven Sequential With Reduced Intensity Conditioning for Refractory Acute Myelodi Leukemia
Not yet reported Shanghai Jiao Tong University School of Medicine 100 participants Est. completion 2026-09-01 3 sites Stand-aloneOther conditions: Refractory LeukemiaView official trial listing → -
Recruiting NCT NCT05873712
Zanubrutinib and Lisocabtagene Maraleucel for the Treatment of Richter's Syndrome
Not yet reported Aseel Alsouqi 24 participants Est. completion 2026-12-31 3 sites Stand-aloneOther conditions: Recurrent Transformed Chronic Lymphocytic Leukemia, Refractory Transformed Chronic Lymphocytic Leukemia, Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma, Recurrent Transformed B-Cell Non-Hodgkin Lymphoma, Recurrent Transformed Non-Hodgkin Lymphoma, Refractory Transformed Non-Hodgkin Lymphoma, Refractory Transformed B-cell Non-Hodgkin Lymphoma, Refractory TransformedView official trial listing → -
Recruiting NCT NCT05877599
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
Not yet reported AstraZeneca 45 participants Est. completion 2029-07-31 20 sites Stand-aloneOther conditions: Non-small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Colorectal Carcinoma, Pancreatic Adenocarcinoma, Breast Cancer, Other Solid Tumors, Ovarian Cancer, Myeloid Neoplasms (AML/MDS)View official trial listing → -
Recruiting NCT NCT05881525
NY-ESO-1 TCR-T Cells for NY-ESO-1 Positive Subjects With Advanced Solid Tumors
Not yet reported TCRCure Biopharma Ltd. 18 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT05884333
Cord Blood Transplant in Adults With Blood Cancers
Not yet reported Memorial Sloan Kettering Cancer Center 54 participants Est. completion 2028-05-22 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML), Myelodysplastic Syndromes (MDS), Myeloproliferative Disorder, Non-Hodgkin's LymphomaView official trial listing → -
Recruiting NCT NCT05900401
Delayed Tolerance Through Mixed Chimerism
Not yet reported, Not yet reported Massachusetts General Hospital 20 participants Est. completion 2032-12 1 site Stand-aloneOther conditions: Kidney Failure, Kidney Transplant; Complications, ChimeraView official trial listing → -
Recruiting NCT NCT05908643
A First-In-Human Trial of pTTL in Advanced Colorectal Cancer
Not yet reported, Not yet reported Neogap Therapeutics AB 16 participants Est. completion 2032-06 2 sites Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Recruiting NCT NCT05909059
CAR T-cell Therapy in Patients With Renal Dysfunction
Not yet reported Northside Hospital, Inc. 20 participants Est. completion 2027-08-31 1 site Stand-aloneOther conditions: Non-hodgkin Lymphoma,B Cell, Multiple Myeloma, Acute Lymphoblastic Leukemia, AdultView official trial listing → -
Recruiting NCT NCT05913804
YTS104 Cell Injection for the Treatment of Relapsed or Refractory Multiple Myeloma
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 12 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: Relapsed or Refractory Multiple MyelomaView official trial listing → -
Recruiting NCT NCT05917405
Study Comparing the Efficacy of 2 RIC Regimens (Clofarabine vs Fludarabine) in Adults With AML Eligible to Allo-SCT
Not yet reported Nantes University Hospital 302 participants Est. completion 2028-09-14 23 sitesOther conditions: Acute Myeloid Leukemia in RemissionView official trial listing → -
Recruiting NCT NCT05926726
GPC3-directed CAR-T in the Treatment Amongst Subjects With Advanced Hepatocellular Carcinoma
Not yet reported RenJi Hospital 12 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05934448
Pembro Plus CAR T-cell Therapy in R/R in PMBCL
Not yet reported Jennifer Crombie, MD 35 participants Est. completion 2031-06-06 2 sites Stand-aloneOther conditions: Primary Mediastinal Large B-cell Lymphoma (PMBCL), Primary Mediastinal Large B Cell Lymphoma, Primary Mediastinal Large B-Cell Lymphoma Refractory, Primary Mediastinal Large B-Cell Lymphoma Recurrent, Epstein-Barr Virus Positive Diffuse Large B-Cell Lymphoma, T-Cell/Histiocyte-Rich Large B-Cell LymphomaView official trial listing → -
Recruiting NCT NCT05947487
CD70 Targeted CAR-T Cells in CD70 Positive Advanced/Metastatic Solid Tumors
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Solid Tumor, AdultView official trial listing → -
Recruiting NCT NCT05948033
CD70 Targeted CAR-T Cells in CD70 Positive Relapsed/Refractory Lymphoma
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Recruiting NCT NCT05949125
Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies (1b Dose Expansion)
Not yet reported AvenCell Europe GmbH 37 participants Est. completion 2028-01 15 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia RefractoryView official trial listing → -
Recruiting NCT NCT05950802
Optimizing lymphoDepletion to Improve Outcomes In Patients Receiving Cell Therapy With Yescarta
Not yet reported University Health Network, Toronto 40 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: DLBCL - Diffuse Large B Cell LymphomaView official trial listing → -
Recruiting NCT NCT05952947
HRYZ-T101 Injection for HPV18 Positive Solid Tumor
Not yet reported HRYZ Biotech Co. 32 participants Est. completion 2028-02 1 site Stand-aloneOther conditions: Cervical Cancer, Head and Neck Squamous Cell Carcinoma, Carcinoma of Vagina, Carcinoma of Penis, Anal Cancer, Carcinoma of VulvaView official trial listing → -
Recruiting NCT NCT05955261
A Study of Venetoclax in Combination With Conventional Chemotherapy in Pediatric Patients With Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 70 participants Est. completion 2034-03 10 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT05963217
Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL
Not yet reported University Health Network, Toronto 19 participants Est. completion 2028-06-30 1 site Stand-aloneOther conditions: Relapsed or Refractory CD19+ B-cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT05981001
Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer
Not yet reported, Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 170 participants Est. completion 2035-04-30 1 site Stand-aloneOther conditions: Breast NeoplasmsView official trial listing → -
Recruiting NCT NCT05981014
Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer
Not yet reported, Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 196 participants Est. completion 2035-05-31 1 site Stand-aloneOther conditions: Breast NeoplasmsView official trial listing → -
Recruiting NCT NCT05989828
A2-ESO-1 TCR-Engineered T Cells for Relapsed/Refractory Advanced or Metastatic NY-ESO-1 Overexpression Positive Triple Negative Breast Cancer
Not yet reported University of Southern California 20 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Triple Negative Breast CancerView official trial listing → -
Recruiting NCT NCT05991908
Randomized Study of Conditioning of Fludarabine Combined With Single or Dual Alkylating Agents in Myeloid Malignancies
Not yet reported Shanghai Jiao Tong University School of Medicine 222 participants Est. completion 2026-06-30 9 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT06001788
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Kura Oncology, Inc. 171 participants Est. completion 2027-08 45 sites Stand-aloneOther conditions: AML, AML With Mutated NPM1, Hematologic Malignancy, KMT2Ar, NPM1 Mutation, MLL Rearrangement, Leukemia, Acute Myeloid Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute, Acute Leukemia, Neoplasms by Histologic TypeView official trial listing → -
Recruiting NCT NCT06002659
CAR20(NAP)-T Therapy for B Cell Lymphoma (CARMA-01 Study)
Not yet reported, Not yet reported Uppsala University 18 participants Est. completion 2027-12-30 2 sites Stand-aloneOther conditions: B-cell LymphomaView official trial listing → -
Recruiting NCT NCT06010472
An Exploratory Clinical Study of Anti-CD19 CAR NK Cells in the Treatment of Systemic Lupus Erythematosus
Not yet reported Changhai Hospital 36 participants Est. completion 2027-08-25 1 site Stand-aloneOther conditions: Systemic Lupus Erythematosus (SLE)View official trial listing → -
Recruiting NCT NCT06010862
Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid Tumors
Not yet reported Chongqing Precision Biotech Co., Ltd 36 participants Est. completion 2026-09-30 1 site Stand-aloneOther conditions: Gastric Cancer, Colon Cancer, Pancreas Cancer, Esophagus Cancer, Cholangiocarcinoma, Lung Cancer, Breast CancerView official trial listing → -
Recruiting NCT NCT06013423
Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases
Not yet reported Fred Hutchinson Cancer Center 54 participants Est. completion 2032-10-31 1 site Stand-aloneOther conditions: Acute Leukemia of Ambiguous Lineage, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Blastic Plasmacytoid Dendritic Cell Neoplasm, Hematopoietic and Lymphatic System Neoplasm, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Non-Hodgkin Lymphoma, Chronic Myeloid Leukemia, BCR-ABL1 PositiveView official trial listing → -
Recruiting NCT NCT06014073
TRAC and Power3 (SPPL3) Genes Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-NHL
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2026-09-01 3 sites Stand-aloneOther conditions: Non Hodgkin's LymphomaView official trial listing → -
Recruiting NCT NCT06026319
CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma
Not yet reported Marcela V. Maus, M.D.,Ph.D. 24 participants Est. completion 2028-01-01 1 site Stand-aloneOther conditions: Non-hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Follicular Lymphoma, Marginal Zone Lymphoma, Diffuse Large B Cell Lymphoma, Primary Mediastinal Large B-cell Lymphoma (PMBCL), High-grade B-cell Lymphoma, Grade 3b Follicular Lymphoma, Mantle Cell LymphomaView official trial listing → -
Recruiting NCT NCT06028828
Risk-ADAPTed Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported University of California, Irvine 60 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: Allogeneic Hematopoietic Stem Cell Transplantation, Allogeneic Stem Cell Transplantation, Hematologic MalignanciesView official trial listing → -
Recruiting NCT NCT06043323
A Phase II Study of Axicabtagene Ciloleucel, an Anti-CD19 Chimeric Antigen Receptor (CAR) Tcell Therapy, in Combination With Radiotherapy (RT) in Relapsed/Refractory Follicular Lymphoma
Not yet reported M.D. Anderson Cancer Center 20 participants Est. completion 2028-09-01 1 site Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Recruiting NCT NCT06043466
A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors
Not yet reported Chongqing Precision Biotech Co., Ltd 30 participants Est. completion 2027-12-31 2 sites Stand-aloneOther conditions: Colorectal Cancer, Esophagus Cancer, Gastric Cancer, Pancreas Cancer, Non-small Cell Lung Cancer, Breast Cancer, Bile Duct CancerView official trial listing → -
Recruiting NCT NCT06043713
Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Solid Tumor Cancers With KRAS G12V Mutations
Not yet reported Fred Hutchinson Cancer Center 24 participants Est. completion 2028-01-01 1 site Stand-aloneOther conditions: Metastatic Malignant Solid NeoplasmView official trial listing → -
Recruiting NCT NCT06047886
UAB 2419-CD34 Selection Using the Automated CliniMACS Prodigy
Not yet reported University of Alabama at Birmingham 50 participants Est. completion 2029-12 1 site Stand-aloneOther conditions: AML, ALL, Lymphoid Malignancies, Myelodysplastic Syndromes, CML, Primary MyelofibrosisView official trial listing → -
Recruiting NCT NCT06047977
Tumor Infiltrating Lymphocyte Therapy for Pediatric High Risk Solid Tumors
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 30 participants Est. completion 2029-09-01 1 site Stand-aloneOther conditions: LymphocytesView official trial listing → -
Recruiting NCT NCT06055439
A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy
Not yet reported, Not yet reported Chimeric Therapeutics 135 participants Est. completion 2027-05 4 sites Stand-aloneOther conditions: Neuroendocrine Tumors, Colorectal Cancer, Gastric CancerView official trial listing → -
Recruiting NCT NCT06056102
CAR-T Cell Therapy for Desensitization in Kidney Transplantation
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 20 participants Est. completion 2042-12-15 3 sites Stand-aloneOther conditions: Kidney Transplant, Kidney Failure, End Stage Renal Failure on DialysisView official trial listing → -
Recruiting NCT NCT06060613
Safety and Efficacy of OBX-115 in Advanced Solid Tumors
Not yet reported, Not yet reported Obsidian Therapeutics, Inc. 208 participants Est. completion 2029-06-30 10 sites Stand-aloneOther conditions: Tumor Skin, Metastatic Melanoma, Melanoma, Lung Cancer, Metastatic Lung Cancer, Non Small Cell Lung Cancer, Metastatic Non Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT06064903
CD7-CAR-T Cells in Pediatric Relapsed/Refractory CD7+ T-ALL/LL
Not yet reported, Not yet reported Bambino Gesù Hospital and Research Institute 26 participants Est. completion 2040-09-30 1 site Stand-aloneOther conditions: T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic LymphomaView official trial listing → -
Recruiting NCT NCT06066359
Ph I/II Trial of Cord Blood-derived NK Cells With NY-ESO-1 TCR/IL-15 for R/R Myeloma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 44 participants Est. completion 2028-08-31 1 site Stand-aloneOther conditions: Relapsed/Refractory MyelomaView official trial listing → -
Recruiting NCT NCT06066424
Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)
Not yet reported M.D. Anderson Cancer Center 54 participants Est. completion 2040-04-30 1 site Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Recruiting NCT NCT06080191
Allogeneic Second-generation CD19-CAR T Cells for Pediatric Relapsed/Refractory B-ALL
Not yet reported Bambino Gesù Hospital and Research Institute 24 participants Est. completion 2041-06-01 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06083129
Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated Donor
Not yet reported Assistance Publique - Hôpitaux de Paris 324 participants Est. completion 2028-11-28 28 sitesOther conditions: GVHDView official trial listing → -
Recruiting NCT NCT06083883
Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1
Not yet reported M.D. Anderson Cancer Center 44 participants Est. completion 2028-11-30 1 site Stand-aloneObstructive sleep apnea Other conditions: Synovial SarcomaView official trial listing → -
Recruiting NCT NCT06084819
Clinical Study of Venetoclax Combined With CACAG Regimen in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Chinese PLA General Hospital 200 participants Est. completion 2030-01-31 1 siteOther conditions: Relapsed/Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06090864
ATLCAR.CD30.CCR4 for CD30+ HL ATLCAR.CD30.CCR4 Cells
Not yet reported, Not yet reported UNC Lineberger Comprehensive Cancer Center 31 participants Est. completion 2033-07-01 1 site Stand-aloneOther conditions: Hodgkin Lymphoma, Relapse, RefractoryView official trial listing → -
Recruiting NCT NCT06092047
UTAA09 Injection in the Treatment of Relapsed/Refractory Hematolymphatic Malignancies.
Not yet reported PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10 participants Est. completion 2028-04 1 site Stand-aloneOther conditions: CD19-positive Relapsed or Refractory B-cell MalignanciesView official trial listing → -
Recruiting NCT NCT06096038
Autologous CAR-T Cells Targeting CSPG4 in Relapsed/Refractory HNSCC
Not yet reported UNC Lineberger Comprehensive Cancer Center 33 participants Est. completion 2028-08-01 1 site Stand-aloneOther conditions: Head and Neck Cancer, Relapse, Recurrent, Refractory CancerView official trial listing → -
Recruiting NCT NCT06111612
Intensive Conditioning withTHI/Bu/Flu/Ara-C in Allo-HSCT for Myeloid Malignancies With Extramedullary Involvement
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 50 participants Est. completion 2027-01-01 1 siteOther conditions: Acute Myeloid Leukemia, Myelodysplastic Neoplasm, Chronic Myelomonocytic Leukemia, Myeloid Sarcoma, Extramedullary Myeloid TumorView official trial listing → -
Recruiting NCT NCT06119685
IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers
Not yet reported, Not yet reported Indapta Therapeutics, INC. 128 participants Est. completion 2029-12-31 12 sites Stand-aloneOther conditions: NHL, Multiple Myeloma, Blood Cancer, Refractory Non-Hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma, Refractory Multiple Myeloma, Relapsed Multiple MyelomaView official trial listing → -
Recruiting NCT NCT06120166
Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of r/r DLBCL Clinical Research
Not yet reported He Huang 18 participants Est. completion 2026-04-05 1 site Stand-aloneOther conditions: Diffuse Large B-cell LymphomaView official trial listing → -
Recruiting NCT NCT06121297
RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus
Not yet reported, Not yet reported Cabaletta Bio 28 participants Est. completion 2029-12 23 sites Stand-aloneOther conditions: Systemic Lupus Erythematosus, Lupus NephritisView official trial listing → -
Recruiting NCT NCT06121557
Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer
Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 24 participants Est. completion 2031-12-31 1 site Stand-aloneOther conditions: Breast NeoplasmsView official trial listing → -
Recruiting NCT NCT06121570
Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes as Neoadjuvant Therapy for HER2-Negative Breast Cancer
Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 24 participants Est. completion 2031-08-31 1 site Stand-aloneOther conditions: Breast NeoplasmsView official trial listing → -
Recruiting NCT NCT06125483
TBI/Flu/Bu/Mel Combined With Secondary UCBT in Patients With Hematological Malignancies Who Relapsed After Allo-HSCT
Not yet reported The First Affiliated Hospital of Soochow University 38 participants Est. completion 2026-10-31 1 site Stand-aloneOther conditions: Hematopoietic Malignancy, Relapse/Recurrence, Hematopoietic Stem Cell TransplantationView official trial listing → -
Recruiting NCT NCT06126406
Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes(CAR-T) for CEA Positive Advanced Malignant Solid Tumors
Not yet reported Chongqing Precision Biotech Co., Ltd 60 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Gastric Cancer, Colon Cancer, Rectal Cancer, Breast Cancer, Lung Cancer, Esophagus Cancer, Cholangiocarcinoma, Pancreas CancerView official trial listing → -
Recruiting NCT NCT06153251
A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myeloma
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 187 participants Est. completion 2030-05-02 19 sites Stand-aloneOther conditions: Relapsed and/or Refractory Multiple MyelomaView official trial listing → -
Recruiting NCT NCT06154252
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
Not yet reported, Not yet reported Cabaletta Bio 74 participants Est. completion 2028-07 35 sites Stand-aloneOther conditions: Idiopathic Inflammatory Myopathy, Dermatomyositis, Anti-Synthetase Syndrome, Immune-Mediated Necrotizing Myopathy, Juvenile Dermatomyositis, Juvenile Polymyositis, Juvenile Idiopathic Inflammatory Myopathy (JIIM), Juvenile MyositisView official trial listing → -
Recruiting NCT NCT06155188
Post-transplant PT/FLU+CY Promotes Unrelated Cord Blood Engraftment in Haplo-cord Setting in Childhood Leukemia
Not yet reported Nanfang Hospital, Southern Medical University 60 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Leukemia, Stem Cell Transplant, Cord BloodView official trial listing → -
Recruiting NCT NCT06158828
Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML
Not yet reported, Not yet reported Washington University School of Medicine 68 participants Est. completion 2030-05-31 1 site Stand-aloneOther conditions: AML, Childhood, Aml, Acute Myeloid Leukemia, Pediatric, Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06170294
MAGE-A4-directed TCR-T in the Treatment Amongst Subjects With Advanced Solid Tumors
Not yet reported Peking University 20 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Recruiting NCT NCT06173518
A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)
Not yet reported Autolus Limited 30 participants Est. completion 2027-11 9 sites Stand-aloneOther conditions: Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia, Relapsed or Refractory B Cell Non-Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT06185751
Safety and Efficacy of CS1 CAR-T (WS-CART-CS1) in Subjects With Multiple Myeloma
Not yet reported Washington University School of Medicine 25 participants Est. completion 2040-08-31 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Recruiting NCT NCT06186401
Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells
Not yet reported Hideho Okada, MD, PhD 20 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: EGFR Gene Mutation, Glioblastoma, MGMT-Unmethylated Glioblastoma, Recurrent GlioblastomaView official trial listing → -
Recruiting NCT NCT06191887
B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies
Not yet reported Mayo Clinic 27 participants Est. completion 2040-12-31 1 site Stand-aloneOther conditions: B-Cell Non-Hodgkin Lymphoma, Recurrent Chronic Lymphocytic Leukemia, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Recurrent Transformed Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, Refractory Diffuse Large B-Cell Lymphoma, Refractory Follicular Lymphoma, Refractory Mantle Cell Lymphoma, Refractory Marginal Zone Lymphoma, Refractory Small Lymphocytic Lymphoma, Refractory Transformed Chronic Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT06193486
Autologous Gamma Delta T Cells to Target Prostate Stem Cell Antigen in mCRPC
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 30 participants Est. completion 2033-12-13 1 site Stand-aloneOther conditions: Metastatic Castration-resistant Prostate CancerView official trial listing → -
Recruiting NCT NCT06193889
KYSA-6: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Patients With Generalized Myasthenia Gravis
Not yet reported, Not yet reported Kyverna Therapeutics 66 participants Est. completion 2028-09 22 sitesOther conditions: Myasthenia Gravis, Generalized Myasthenia GravisView official trial listing → -
Recruiting NCT NCT06195891
Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome
Not yet reported City of Hope Medical Center 33 participants Est. completion 2030-03-22 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT06198842
Low Dose Treosulfan Based Conditioning Regimen and PTCy in HSCT for Nijmegen Breakage Syndrome
Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 10 participants Est. completion 2029-01-31 1 site Stand-aloneOther conditions: Nijmegen Breakage SyndromeView official trial listing → -
Recruiting NCT NCT06199427
PTCy and and Ruxolitinib for GVHD Prophylaxis After HSCT With Thymoglobulin in Conditioning Regimen in Patients With Inborn Errors of Immunity
Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 100 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Inborn Errors of ImmunityView official trial listing → -
Recruiting NCT NCT06204991
To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma
Not yet reported Inge Marie Svane 10 participants Est. completion 2028-04-01 2 sites Stand-aloneOther conditions: Melanoma Stage III, Melanoma Stage IV, MelanomaView official trial listing → -
Recruiting NCT NCT06208735
CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies
Not yet reported British Columbia Cancer Agency 24 participants Est. completion 2027-08-01 7 sites Stand-aloneOther conditions: B-Cell Leukemia, Non-Hodgkin's Lymphoma, B-cell Acute Lymphoblastic Leukemia, Diffuse Large B Cell Lymphoma, High-grade B-cell Lymphoma, Primary Mediastinal Large B-cell Lymphoma (PMBCL), Mantle Cell Lymphoma, B-cell LymphomaView official trial listing → -
Recruiting NCT NCT06213636
Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia (PMBCL/CNS-BCL).
Not yet reported, Not yet reported Essen Biotech 75 participants Est. completion 2028-12-10 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult B-Cell, Acute Lymphoblastic Leukemia, in Relapse, Non-Hodgkin Lymphoma, B-cell, Diffuse Large B Cell Lymphoma, Central Nervous System Lymphoma, Lymphoma, Follicular, MCLView official trial listing → -
Recruiting NCT NCT06215950
A Clinical Research About CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Gynecologic Cancer
Not yet reported Chongqing Precision Biotech Co., Ltd 36 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Ovarian Cancer, Cervix Cancer, Metastatic Cancer, Advanced Cancer, Gynecologic CancerView official trial listing → -
Recruiting NCT NCT06236139
Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 48 participants Est. completion 2027-03-30 1 site Stand-aloneOther conditions: Metastatic Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IVB Prostate Cancer AJCC v8View official trial listing → -
Recruiting NCT NCT06241456
FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors
Not yet reported Fate Therapeutics 351 participants Est. completion 2044-05-01 14 sites Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Recruiting NCT NCT06247787
A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy
Not yet reported Children's Oncology Group 36 participants Est. completion 2028-03-31 19 sites Stand-aloneOther conditions: Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Myelodysplastic Syndrome, Recurrent Juvenile Myelomonocytic Leukemia, Refractory Childhood Acute Myeloid Leukemia, Refractory Childhood Myelodysplastic Syndrome, Refractory Juvenile Myelomonocytic LeukemiaView official trial listing → -
Recruiting NCT NCT06249256
An Exploratory Study on the Treatment of Advanced Solid Tumors by Fast CAR T Cells
Not yet reported Shanghai Cell Therapy Group Co.,Ltd 12 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Recruiting NCT NCT06252870
Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation
Not yet reported Nantes University Hospital 82 participants Est. completion 2028-07-18 3 sites Stand-aloneOther conditions: Graft Versus Host Disease, Hematologic MalignancyView official trial listing → -
Recruiting NCT NCT06262438
CHIP-AML22/Quizartinib: Quizartinib + Chemotherapy in Newly Diagnosed Pediatric FLT3-ITD+ and NPM1wt AML Patients
Not yet reported Princess Maxima Center for Pediatric Oncology 60 participants Est. completion 2032-06 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia in ChildrenView official trial listing → -
Recruiting NCT NCT06265584
Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant
Not yet reported University of Alabama at Birmingham 56 participants Est. completion 2028-11 1 site Stand-aloneOther conditions: Acute Leukemia, Myelodysplastic Syndrome, Myeloproliferative DisordersView official trial listing → -
Recruiting NCT NCT06285279
The BCMA/CD19 Dual Targeted CAR-T Cell in Participants With Autoimmune Kidney Diseases
Not yet reported Nanjing University School of Medicine 24 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Lupus Nephritis, ANCA-associated Vasculitis, Membranous Nephropathy - PLA2R Induced, IgG4-Related DiseasesView official trial listing → -
Recruiting NCT NCT06287944
225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome
Not yet reported City of Hope Medical Center 15 participants Est. completion 2028-05-19 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT06305299
Autologous CAR-T Cells Targeting B7H3 in Ovarian Cancer iC9-CAR.B7-H3 T Cells
Not yet reported UNC Lineberger Comprehensive Cancer Center 27 participants Est. completion 2036-04 1 site Stand-aloneOther conditions: Ovary Neoplasm, Ovarian Cancer, Epithelial Ovarian Cancer, RecurrentView official trial listing → -
Recruiting NCT NCT06308978
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
Not yet reported Fate Therapeutics 244 participants Est. completion 2042-09-30 21 sites Stand-aloneOther conditions: Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV), Idiopathic Inflammatory Myositis (IIM), Systemic Sclerosis (SSc), Systemic Lupus Erythematosus (SLE), Lupus NephritisView official trial listing → -
Recruiting NCT NCT06313957
A Study of LUCAR-20SP in Subjects With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported Peking University Cancer Hospital & Institute 42 participants Est. completion 2028-09 3 sites Stand-aloneOther conditions: Relapsed B-cell Non-Hodgkin Lymphoma, Refractory B-cell Non-Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT06315309
Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant
Not yet reported University of Alabama at Birmingham 29 participants Est. completion 2027-05 1 site Stand-aloneOther conditions: GVHD,Acute, Acute Leukemia, Myelodysplastic Syndromes, Myeloproliferative DisordersView official trial listing → -
Recruiting NCT NCT06316791
Exploratory Clinical Study of CNCT19 Anti CD19 Cell Therapy in the Treatment of Refractory Autoimmune Diseases
Not yet reported Juventas Cell Therapy Ltd. 24 participants Est. completion 2025-12-13 1 site Stand-aloneOther conditions: Lupus Erythematosus, SystemicView official trial listing → -
Recruiting NCT NCT06318533
A Clinical Study of CAR NK Cells for the Treatment of Relapsed/Refractory B-cell Related Autoimmune Diseases
Not yet reported YANRU WANG 15 participants Est. completion 2027-03-13 2 sites Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Recruiting NCT NCT06319456
A Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL.
Not yet reported Ascentage Pharma Group Inc. 344 participants Est. completion 2028-08 10 sitesOther conditions: CLL/SLLView official trial listing → -
Recruiting NCT NCT06321289
Allogeneic TRAC Locus-inserted CD19-targeting STAR T Cell Therapy in r/r B-NHL
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2027-03-20 2 sites Stand-aloneOther conditions: Non-hodgkin Lymphoma,B CellView official trial listing → -
Recruiting NCT NCT06323525
TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B Cell Lymphoma
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2027-04-25 3 sites Stand-aloneOther conditions: Non-hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT06326463
CAR T-cell Therapy Directed to CD70 for Pediatric Patients With Hematological Malignancies
Not yet reported St. Jude Children's Research Hospital 18 participants Est. completion 2031-07-01 1 site Stand-aloneOther conditions: Hematologic Malignancy, ALL, Childhood, AML, Childhood, Lymphoma, MDSView official trial listing → -
Recruiting NCT NCT06328777
RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis
Not yet reported, Not yet reported Cabaletta Bio 37 participants Est. completion 2029-07 10 sites Stand-aloneOther conditions: Systemic Sclerosis, Scleroderma, Interstitial Lung DiseasesView official trial listing → -
Recruiting NCT NCT06336395
Ma-Spore ALL 2020 Study
Not yet reported National University Hospital, Singapore 500 participants Est. completion 2030-03 3 sites Stand-aloneOther conditions: B Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06337474
An Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Primary Immune Thrombocytopenia
Not yet reported Changzhou No.2 People's Hospital 9 participants Est. completion 2026-07-30 1 site Stand-aloneOther conditions: Thrombocytopenia AlloimmuneView official trial listing → -
Recruiting NCT NCT06345495
High Dose Ruxolitinib and Allogeneic Stem Cell Transplantation in Myelofibrosis Patients With Splenomegaly
Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2029-01-01 1 site Stand-aloneOther conditions: Splenomegaly, MyelofibrosisView official trial listing → -
Recruiting NCT NCT06347068
Study of Autologous CAR-T Cells Targeting B7-H3 in TNBC iC9-CAR.B7-H3 T Cells
Not yet reported UNC Lineberger Comprehensive Cancer Center 42 participants Est. completion 2030-05 1 site Stand-aloneOther conditions: Breast Cancer, Relapse, Resistant Cancer, Triple Negative Breast CancerView official trial listing → -
Recruiting NCT NCT06348797
Phase I Clinical Study of α-PD-L1/DLL3 CAR-T in Patients With R/R SCLC
Not yet reported Sichuan University 30 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Small Cell Lung Cancer Extensive StageView official trial listing → -
Recruiting NCT NCT06350110
Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)
Not yet reported, Not yet reported Essen Biotech 75 participants Est. completion 2025-12-28 1 site Stand-aloneOther conditions: Systemic Lupus Erythematosus, Lupus Nephritis, Autoimmune Diseases, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Granulomatous Polyangiitis, Microscopic Polyangiitis, Systemic Sclerosis, Idiopathic Inflammatory Myopathies, Sjogren's SyndromeView official trial listing → -
Recruiting NCT NCT06352281
Efficacy and Safety of CAR-T Cells Therapy for Chronic or Refractory Primary Immune Thrombocytopenia (ITP)
Not yet reported, Not yet reported 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China 10 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: ITP - Immune ThrombocytopeniaView official trial listing → -
Recruiting NCT NCT06359041
RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis
Not yet reported, Not yet reported Cabaletta Bio 24 participants Est. completion 2029-09 17 sites Stand-aloneOther conditions: Generalized Myasthenia Gravis (gMG)View official trial listing → -
Recruiting NCT NCT06364423
Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias
Not yet reported, Not yet reported National Cancer Institute (NCI) 132 participants Est. completion 2030-07-01 1 site Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-Cell, B-Lymphocytic Leukemia, Chronic, B-Cell Chronic Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Lymphoblastic Lymphoma, Leukemia, Acute Lymphoblastic, Small Lymphocytic LymphomaView official trial listing → -
Recruiting NCT NCT06376162
Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia
Not yet reported PedAL BCU, LLC 20 participants Est. completion 2027-01 20 sites Stand-aloneOther conditions: Relapsed/Refractory KMT2A-r Acute Leukemia, Relapsed/Refractory NUP98-r Acute Leukemia, Relapsed/Refractory NPM1-m Acute LeukemiaView official trial listing → -
Recruiting NCT NCT06378060
Clinical Study on Modified Allogeneic Hematopoietic Stem Cell Transplantation Regimen for Severe Aplastic Anemia
Not yet reported Hematology department of the 920th hospital 30 participants Est. completion 2027-04-01 1 site Stand-aloneOther conditions: Severe Aplastic AnemiaView official trial listing → -
Recruiting NCT NCT06383572
Phase I/II Study of Engineered T Cell Receptor-Modified NK Cells Targeting PRAME in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Myeloid Malignancies
Not yet reported, Not yet reported M.D. Anderson Cancer Center 44 participants Est. completion 2029-04-01 1 site Stand-aloneOther conditions: Lymphodepleting Chemotherapy, Myeloid MalignanciesView official trial listing → -
Recruiting NCT NCT06387069
A Study to Evaluate HMPL-306 in Patients With IDH1or IDH2-mutated Acute Myeloid Leukemia
Not yet reported Hutchmed 316 participants Est. completion 2029-09-30 53 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06395870
Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported Tianjin Medical University Cancer Institute and Hospital 33 participants Est. completion 2028-06-30 2 sites Stand-aloneOther conditions: B-Cell Non-Hodgkin Lymphoma-Recurrent, B-Cell Non-Hodgkin Lymphoma-RefractoryView official trial listing → -
Recruiting NCT NCT06412497
MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.
Not yet reported Masonic Cancer Center, University of Minnesota 60 participants Est. completion 2036-05-01 1 site Stand-aloneOther conditions: Severe Aplastic Anemia, Acquired Amegakaryocytic Thrombocytopenia, Acquired Pure Red Cell Aplasia, Paroxysmal Nocturnal HemoglobinuriaView official trial listing → -
Recruiting NCT NCT06415487
ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)
Not yet reported Acepodia Biotech, Inc. 30 participants Est. completion 2027-03-27 9 sites Stand-aloneOther conditions: Locally Advanced Solid Tumor, Metastatic Solid TumorView official trial listing → -
Recruiting NCT NCT06420063
Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AML
Not yet reported, Not yet reported Essen Biotech 85 participants Est. completion 2026-12-28 1 site Stand-aloneOther conditions: AML, Acute Myeloid Leukemia, AML, Adult Recurrent, AML, AdultView official trial listing → -
Recruiting NCT NCT06420076
Sequential CAR-T Cells Therapy for CD5/CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD5/CD7-Specific CAR-T Cells
Not yet reported, Not yet reported Essen Biotech 60 participants Est. completion 2026-12-28 1 site Stand-aloneOther conditions: T Cell Lymphoma, T Cell Leukemia, T-cell Acute Lymphoblastic Leukemia, T-Cell Lymphoma of CNS, T Cell Prolymphocytic Leukemia, T Cell Childhood ALLView official trial listing → -
Recruiting NCT NCT06420089
CD5-deleted Chimeric Antigen Receptor Cells (Senza5 CART5) for T Cell Non-Hodgkin Lymphoma (NHL)
Not yet reported Vittoria Biotherapeutics 30 participants Est. completion 2029-08-30 2 sites Stand-aloneOther conditions: T Cell Non-Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT06428188
Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune Diseases
Not yet reported, Not yet reported Essen Biotech 60 participants Est. completion 2026-12-28 1 site Stand-aloneOther conditions: Autoimmune Diseases, Systemic Lupus Erythematosus, Systemic Lupus Erythematosus Acute, Sjogren's SyndromeView official trial listing → -
Recruiting NCT NCT06434363
Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders
Not yet reported, Not yet reported M.D. Anderson Cancer Center 47 participants Est. completion 2030-12-31 2 sites Stand-aloneOther conditions: Autoimmune Disorders, Systemic Sclerosis, Systemic Lupus Erythematosus, Lupus, Lupus NephritisView official trial listing → -
Recruiting NCT NCT06445803
CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL
Not yet reported Rong Tao 48 participants Est. completion 2026-12 2 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia With Failed Remission, B-cell Lymphoma Refractory, B-cell Lymphoma RecurrentView official trial listing → -
Recruiting NCT NCT06446128
A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed or Refractory B Cell Non-Hodgkin Lymphoma(NHL)
Not yet reported Shanghai Cell Therapy Group Co.,Ltd 20 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Non-Hodgkin Lymphoma, B-cellView official trial listing → -
Recruiting NCT NCT06455917
TIL Therapy in Non-small-cell Lung Cancer (NSCLC) Patients
Not yet reported University Hospital, Basel, Switzerland 30 participants Est. completion 2029-12 1 site Stand-aloneOther conditions: Non-Small Cell Lung Cancer, Lung Cancer (NSCLC)View official trial listing → -
Recruiting NCT NCT06464679
An Exploratory Clinical Study of CD19 CAR NK Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases
Not yet reported Changhai Hospital 72 participants Est. completion 2026-06-30 1 site Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Recruiting NCT NCT06469190
An Exploratory Clinical Study of Anti-CD19 CAR NK Cell (KN5501) in the Treatment of Relapsed/Refractory Immune Nephropathy
Not yet reported Changhai Hospital 36 participants Est. completion 2027-06-20 1 site Stand-aloneOther conditions: NephropathyView official trial listing → -
Recruiting NCT NCT06477549
BeFluBu vs FluBuRux Conditioning in Haploidentical HCT
Not yet reported St. Petersburg State Pavlov Medical University 220 participants Est. completion 2029-06 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Biphenotypic Acute Leukemia, Lymphoblastic Lymphoma, Myeloproliferative Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT06478225
Evaluate the Safety and Efficacy of BGT007H Cell Therapy in Patients With Relapsed/Refractory Pancreatic Cancer
Not yet reported RenJi Hospital 12 participants Est. completion 2027-08-31 1 site Stand-aloneOther conditions: Tumor PancreasView official trial listing → -
Recruiting NCT NCT06481592
A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Endometrial Cancer.
Not yet reported Iovance Biotherapeutics, Inc. 60 participants Est. completion 2029-11 12 sites Stand-aloneOther conditions: Endometrial CancerView official trial listing → -
Recruiting NCT NCT06481735
TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-ALL
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2028-02-15 6 sites Stand-aloneOther conditions: Acute Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT06482684
CAR-T-cell Treatment for Untreated High Risk MANtle Cell Lymphoma
Not yet reported Christian Schmidt, MD 150 participants Est. completion 2031-12-31 2 sites Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Recruiting NCT NCT06486051
A Study of Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell Lymphoma
Not yet reported Malaghan Institute of Medical Research 60 participants Est. completion 2029-06-30 3 sites Stand-aloneOther conditions: Large B-cell Lymphoma, Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Primary Mediastinal Large B-cell Lymphoma (PMBCL), Transformed Non-Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT06494371
A Study of LCAR-HL30 in Subjects With Relapsed/Refractory Hodgkin's Lymphoma and Anaplastic Large Cell Lymphoma
Not yet reported Ruijin Hospital 32 participants Est. completion 2028-08 1 site Stand-aloneOther conditions: Hodgkin's Lymphoma, Anaplastic Large Cell LymphomaView official trial listing → -
Recruiting NCT NCT06500273
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Not yet reported Allogene Therapeutics 250 participants Est. completion 2032-12 85 sites Stand-aloneOther conditions: Large B-cell LymphomaView official trial listing → -
Recruiting NCT NCT06500819
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors
Not yet reported Stanford University 41 participants Est. completion 2029-07 1 site Stand-aloneObstructive sleep apnea Other conditions: Neuroblastoma, SarcomaView official trial listing → -
Recruiting NCT NCT06503224
An Exploratory Clinical Study of SCAR02 Targeting BCMA and CD19 for the Treatment of Refractory Autoimmune Diseases
Not yet reported The First Affiliated Hospital of University of Science and Technology of China 18 participants Est. completion 2028-04-30 1 site Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Recruiting NCT NCT06503237
Safety and Efficacy of SWK002 in Patients With D2T-Rheumatoid Arthritis
Not yet reported The First Affiliated Hospital of University of Science and Technology of China 18 participants Est. completion 2026-03 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT06512519
Second Haplo-transplantation for Graft Failure
Not yet reported Peking University People's Hospital 34 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Graft Failure, Stem Cell Transplant ComplicationsView official trial listing → -
Recruiting NCT NCT06512545
Modified Second Haplo-transplantation for Graft Failure
Not yet reported Peking University People's Hospital 12 participants Est. completion 2026-06-30 1 site Stand-aloneOther conditions: Graft Failure, Stem Cell Transplant ComplicationsView official trial listing → -
Recruiting NCT NCT06515314
HRYZ-T102 TCR-T Cell for AFP Positive Advanced HCC and Other Solid Tumors
Not yet reported Shanghai Ruiliyuan Biotechnology Co., Ltd. 12 participants Est. completion 2027-08-10 1 site Stand-aloneOther conditions: Hepatic Cell CarcinomaView official trial listing → -
Recruiting NCT NCT06517004
An Open-label, Single-arm Study of JWCAR201 in the Treatment of Relapsed or Refractory Diffuse Large B-cell Lymphoma
Not yet reported Fudan University 9 participants Est. completion 2027-08 1 site Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Recruiting NCT NCT06517641
Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia
Not yet reported Medical College of Wisconsin 60 participants Est. completion 2029-02-01 25 sitesOther conditions: Severe Aplastic AnemiaView official trial listing → -
Recruiting NCT NCT06519565
Safety and Efficacy of PRG-1801 in Recurrent/Refractory Primary Immune Thrombocytopenia (ITP)
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 6 participants Est. completion 2027-08-15 2 sites Stand-aloneOther conditions: Immune ThrombocytopeniaView official trial listing → -
Recruiting NCT NCT06530303
Biological Tumor Infiltrating Lymphocytes Therapy With Immunotherapy for Colon and Rectum Cancer
Not yet reported, Not yet reported Essen Biotech 85 participants Est. completion 2026-12-28 1 site Stand-aloneOther conditions: Colorectal Cancer, Colon Cancer, Rectum CancerView official trial listing → -
Recruiting NCT NCT06532799
TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Stomach and Esophageal Cancer
Not yet reported, Not yet reported Essen Biotech 75 participants Est. completion 2026-12-28 1 site Stand-aloneOther conditions: Stomach Cancer, Stomach Cancer Recurrent, Stomach Cancer, Adenocarcinoma, Esophageal Cancer, Esophageal Cancer Metastatic to Bone, Esophageal Cancer Metastatic to Lung, Esophageal Cancer Metastatic to LiverView official trial listing → -
Recruiting NCT NCT06532812
TIL Gean Therapy Combined With Immunotherapy for Advanced or Metastatic Refractory Breast Cancer
Not yet reported, Not yet reported Essen Biotech 85 participants Est. completion 2026-12-28 1 site Stand-aloneOther conditions: Breast Cancer, Breast Carcinoma, Breast Cancer Metastatic, Breast Cancer Triple NegativeView official trial listing → -
Recruiting NCT NCT06538012
TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Lung Cancer
Not yet reported, Not yet reported Essen Biotech 85 participants Est. completion 2026-12-28 1 site Stand-aloneOther conditions: Lung Cancer, Lung Cancer Metastatic, Lung Cancer, Non-small Cell, Lung Cancer RecurrentView official trial listing → -
Recruiting NCT NCT06546150
RE002 T Cell Injection for the Treatment of KRAS G12D Mutated Solid Tumors
Not yet reported Henan Cancer Hospital 30 participants Est. completion 2027-04-01 1 site Stand-aloneOther conditions: KRAS G12D, T Cell TherapyView official trial listing → -
Recruiting NCT NCT06548607
Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases
Not yet reported Nanjing Bioheng Biotech Co., Ltd. 20 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: SLE (Systemic Lupus), Systemic Sclerosis, ANCA Associated Vasculitis, Idiopathic Inflammatory Myopathies, Sjogren's Syndrome, Autoimmune DiseasesView official trial listing → -
Recruiting NCT NCT06550141
Emapalumab Prevention of CAR-T Cell Associated Toxicities
Not yet reported Marcela V. Maus, M.D.,Ph.D. 28 participants Est. completion 2027-08-01 2 sites Stand-aloneOther conditions: Large B-cell Lymphoma, Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, Primary Mediastinal Large B-cell Lymphoma, High-grade B-cell Lymphoma, Follicular LymphomaView official trial listing → -
Recruiting NCT NCT06571825
RIC Allo-HSCT vs. Venetoclax-Based Consolidation in Elderly AML Patients After First CR
Not yet reported He Huang 118 participants Est. completion 2028-02-28 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06581562
Open-label Single-Center Study to Evaluate the Safety and Efficacy of Combining Rituximab and AB-101 in B-cell Associated Autoimmune Diseases.
Not yet reported IRIS Research and Development, LLC 30 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Rheumatoid Arthritis, Pemphigus Vulgaris, Granulomatosis With Polyangiitis, Systemic Lupus ErythematosusView official trial listing → -
Recruiting NCT NCT06585514
Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Systemic Lupus Erythematosus
Not yet reported, Not yet reported Beijing GoBroad Hospital 18 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Systemic Lupus Erythematosus (SLE), Lupus Nephritis (LN)View official trial listing → -
Recruiting NCT NCT06598371
A Phase 1/2 Study of KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors
Not yet reported, Not yet reported M.D. Anderson Cancer Center 141 participants Est. completion 2041-08-01 1 site Stand-aloneOther conditions: Select Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT06609928
FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported Fred Hutchinson Cancer Center 12 participants Est. completion 2042-10-01 1 site Stand-aloneOther conditions: Recurrent Childhood Acute Myeloid Leukemia, Refractory Childhood Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06613490
An Exploratory Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Antisynthetase Antibody Syndrome and Rheumatoid Arthritis
Not yet reported The First Affiliated Hospital with Nanjing Medical University 24 participants Est. completion 2026-10-20 1 site Stand-aloneOther conditions: Antisynthetase Syndrome, Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT06614270
Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 15 participants Est. completion 2027-01-06 1 site Stand-aloneOther conditions: Systemic Sclerosis (SSc), ANCA Associated Vasculitis (AAV), Idiopathic Inflammatory Myopathy (IIM), Sjogren's Syndrome, Antiphospholipid Syndrome, Systemic Lupus ErythematosusView official trial listing → -
Recruiting NCT NCT06615479
A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 440 participants Est. completion 2032-06-22 141 sites Stand-aloneOther conditions: Relapsed or Refractory Multiple Myeloma (RRMM)View official trial listing → -
Recruiting NCT NCT06622694
CD7 CAR T Cells (RD13-02) in the Treatment of Relapsed/Refractory Severe Aplastic Anemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 15 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Severe Aplastic Anemia, Relapse, Refractory, CAR T-cell TherapyView official trial listing → -
Recruiting NCT NCT06630611
Evaluation of a Pragmatic Approach to Adoptive Cell Therapy (ACT) Using an IL2 Analog (ANV419) vs High Dose IL2 After Tumor Infiltrating Lymphocytes (TIL) Therapy in Patients With Melanoma, NSCLC and Cervical Cancer (PragmaTIL)
Not yet reported Vall d'Hebron Institute of Oncology 40 participants Est. completion 2029-09 1 site Stand-aloneOther conditions: Melanoma, Non Small Cell Lung Cancer, Cervical CancerView official trial listing → -
Recruiting NCT NCT06640582
TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas
Not yet reported, Not yet reported Essen Biotech 85 participants Est. completion 2026-12-28 1 site Stand-aloneOther conditions: Brain Tumor, Brain Metastases, Brain Cancer, Glioma, Gliomas, Malignant, Glioblastoma, MeningiomaView official trial listing → -
Recruiting NCT NCT06642025
EX02 CAR-T Cells for Relapsed and Refractory Acute Myeloid Leukemia
Not yet reported Zhimin Zhai 9 participants Est. completion 2029-09-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), CAR-TView official trial listing → -
Recruiting NCT NCT06646497
Indication of HSCT in Patients With Refractory/Relapse AA After First-line Standard Immunosuppressive Therapy Aged More Than 40 Years
Not yet reported Assistance Publique - Hôpitaux de Paris 52 participants Est. completion 2030-01-24 26 sites Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Recruiting NCT NCT06652243
Clinical Study of SN301A Injection in the Treatment of Hepatocellular Carcinoma
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 12 participants Est. completion 2027-10-31 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT06658951
Anti-HER2 CAR-T Cell Injection in Patients With HER2-positive Advanced Malignant Solid Tumors
Not yet reported UTC Therapeutics Inc. 30 participants Est. completion 2028-04-30 1 site Stand-aloneOther conditions: HER2-positive Advanced Malignant Solid TumorsView official trial listing → -
Recruiting NCT NCT06660420
Phase 1 Dose Escalation and Expansion Study of PRAME T Cell Receptor (TCR) Engineered NK Cells in Participants With Recurrent and/or Refractory Melanoma (PRAMETIME-Mel)
Not yet reported M.D. Anderson Cancer Center 39 participants Est. completion 2031-12-31 1 site Stand-aloneOther conditions: Phase 1, Recurrent Melanoma, Refractory MelanomaView official trial listing → -
Recruiting NCT NCT06674382
Haplo-HSCT for Myelofibrosis
Not yet reported Peking University People's Hospital 39 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: MyelofibrosisView official trial listing → -
Recruiting NCT NCT06680752
Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS
Not yet reported, Not yet reported ARCE Therapeutics, Inc. 49 participants Est. completion 2028-12 3 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory, MDS (Myelodysplastic Syndrome)View official trial listing → -
Recruiting NCT NCT06688799
Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Autoimmune Diseases
Not yet reported, Not yet reported Beijing GoBroad Hospital 18 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Recruiting NCT NCT06689917
JY231(JY231) Injection for the Treatment of Relapsed or Refractory B Cell Lymphoma/ Leukemia
Not yet reported Tongji Hospital 20 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: B-ALL, B-NHLView official trial listing → -
Recruiting NCT NCT06696833
Allogeneic CD19-targeted CAR-γδT Cell Infusion Therapy in Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia
Not yet reported The First Affiliated Hospital of Soochow University 18 participants Est. completion 2025-12-01 1 site Stand-aloneOther conditions: B-Cell Acute Lymphoblastic Leukemia, AdultView official trial listing → -
Recruiting NCT NCT06697665
An Exploratory Clinical Study to Evaluate the Safety, Tolerability, Immune Response and Preliminary Efficacy of LM103 Injection in Combination With PD-1 in Patients With Advanced Solid Tumours
Not yet reported Suzhou BlueHorse Therapeutics Co., Ltd. 10 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Solid CancerView official trial listing → -
Recruiting NCT NCT06699771
Phase 1 to Investigate the Safety, Tolerability, and Efficacy of GCC2005 in Patients With R/R NK and T-cell Malignancies
Not yet reported GC Cell Corporation 53 participants Est. completion 2027-08 3 sites Stand-aloneOther conditions: Lymphoma, T-CellView official trial listing → -
Recruiting NCT NCT06708845
US Zamto-cel Autoimmune Diseases
Not yet reported Miltenyi Biomedicine GmbH 48 participants Est. completion 2028-07 1 site Stand-aloneOther conditions: Lupus Nephritis, Systemic Lupus Erythematosus, Systemic Sclerosis (SSc), Diffuse Cutaneous Systemic SclerosisView official trial listing → -
Recruiting NCT NCT06711146
Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Moderate to Severe Active SLE Clinical Research
Not yet reported Zhejiang University 36 participants Est. completion 2027-04-05 1 site Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Recruiting NCT NCT06713837
IMPACT-AML: A Randomized Pragmatic Clinical Trial for Relapsed or Refractory Acute Myeloid Leukemia.
Not yet reported Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS 339 participants Est. completion 2028-01 47 sitesOther conditions: Acute Myeloid Leukemia, Relapse/RecurrenceView official trial listing → -
Recruiting NCT NCT06716164
Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of r/r B-NHL Clinical Research
Not yet reported Zhejiang University 36 participants Est. completion 2027-04-05 1 site Stand-aloneOther conditions: Non-hodgkin Lymphoma,B CellView official trial listing → -
Recruiting NCT NCT06718738
Clinical Study of IM96 CAR-T Cell Therapy in Patients With Advanced Colorectal Cancer
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 9 participants Est. completion 2026-08-15 1 site Stand-aloneOther conditions: Colorectal Cancer (CRC)View official trial listing → -
Recruiting NCT NCT06720324
CD7-specific CAR-T Cell in the Treatment of CD7-positive Relapsed/Refractory Hematologic Tumors
Not yet reported, Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 80 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Hematologic MalignancyView official trial listing → -
Recruiting NCT NCT06728189
A Clinical Research About CD70-targeted CAR-NKT Cells Therapy in Subjects with Advanced Malignant Solid Tumors
Not yet reported Peking University Cancer Hospital & Institute 13 participants Est. completion 2026-10-17 1 site Stand-aloneOther conditions: Advanced Malignant Solid TumorsView official trial listing → -
Recruiting NCT NCT06732232
A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed/ Refractory Multiple Myeloma
Not yet reported Shanghai Cell Therapy Group Co.,Ltd 12 participants Est. completion 2027-12-12 1 site Stand-aloneOther conditions: Relapsed, Refractory, Multiple MyelomaView official trial listing → -
Recruiting NCT NCT06733935
A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)
Not yet reported, Not yet reported Nkarta, Inc. 240 participants Est. completion 2028-10 18 sites Stand-aloneOther conditions: Systemic Sclerosis, Idiopathic Inflammatory Myopathies, Antineutrophil Cytoplasmic Antibody-Associated Vasculitis, Rheumatoid ArthritisView official trial listing → -
Recruiting NCT NCT06743126
SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous Melanoma
Not yet reported Immatics US, Inc. 360 participants Est. completion 2031-10 71 sites Stand-aloneOther conditions: Melanoma, Cutaneous MalignantView official trial listing → -
Recruiting NCT NCT06756152
Preventing of GVHD with Post-transplantation Cyclophosphamide, Abatacept, Vedolizumab and Ruxolitinib At Children and Young Adults with Hemoblastosis
Not yet reported, Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 50 participants Est. completion 2026-10-10 1 site Stand-aloneOther conditions: Biphenotypic Acute Leukemia, Acute Lymphoblastic Leukemia, Myeloblastic Leukemia, Bilinear Leukemia, Malignant Lymphoma, Non-Hodgkin, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT06756321
A Study of CAR T-Cells in Relapsed/Refractory Hematologic Malignancy
Not yet reported Affiliated Hospital of Nantong University 9 participants Est. completion 2026-03-18 1 site Stand-aloneOther conditions: Relapsed/refractory Lymphoma, Relapsed/Refractory LeukemiaView official trial listing → -
Recruiting NCT NCT06768151
A Clinical Trial of CEA Targeting CAR-T for CEA Positive Advanced Lung Cancer
Not yet reported Chongqing Precision Biotech Co., Ltd 48 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Advanced Lung CancerView official trial listing → -
Recruiting NCT NCT06773091
A Phase I Study of NK042 Cell Injection in Advanced Solid Tumors
Not yet reported Shanghai NK Cell Technology Co., LTD 76 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT06775912
Clinical Study on Targeted CD19/BCMA CAR-T Therapy for Autoimmune Diseases
Not yet reported Nanjing Bioheng Biotech Co., Ltd. 18 participants Est. completion 2027-06-01 1 site Stand-aloneOther conditions: SLE, Systemic Sclerosis, IIM, NMOSD, MS, MG, ANCA Associated Vasculitis (AAV)View official trial listing → -
Recruiting NCT NCT06777979
CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia
Not yet reported St. Jude Children's Research Hospital 30 participants Est. completion 2031-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Recurrent Acute Lymphoblastic Leukemia, Recurrent B Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06783270
T-cell Therapy with CRISPR PD1-edited Tumor Infiltrating Lymphocytes for Patients with Metastatic Melanoma
Not yet reported Inge Marie Svane 10 participants Est. completion 2028-01-01 1 site Stand-aloneOther conditions: Melanoma MetastaticView official trial listing → -
Recruiting NCT NCT06786533
Clinical Study of Anti-FLT3 CAR-T Cells for the Treatment of Relapsed/Refractory AML
Not yet reported Hemogenyx Pharmaceuticals LLC 18 participants Est. completion 2027-01 1 site Stand-aloneOther conditions: Relapsed/Refractory Acute Myeloid Leukemia (R/R AML)View official trial listing → -
Recruiting NCT NCT06792799
Anti-CD19/BCMA CAR-NK Cells in Patients With B Cell Mediated Autoimmune Disease
Not yet reported The Children's Hospital of Zhejiang University School of Medicine 36 participants Est. completion 2029-06-30 1 site Stand-aloneOther conditions: Autoimmune Diseases, Systemic Lupus Erthematosus, Multi-Drug Resistant Nephrotic Syndrome, IgAN - IgA NephropathyView official trial listing → -
Recruiting NCT NCT06802315
Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)
Not yet reported University of Illinois at Chicago 38 participants Est. completion 2032-03 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Relapsed, Adult, Acute Myeloid Leukemia Refractory, Chronic Myeloid Leukemia - Accelerated Phase, Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT06807606
Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk Hematologic Malignancies Who Have Relapsed After First Allogeneic Stem Cell Transplantation
Not yet reported M.D. Anderson Cancer Center 35 participants Est. completion 2029-11-30 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Recruiting NCT NCT06809699
Human Leukocyte Antigen (HLA) Mismatched Related Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported He Huang 29 participants Est. completion 2027-10-31 1 site Stand-aloneOther conditions: Hematologic DiseasesView official trial listing → -
Recruiting NCT NCT06809712
Human Leukocyte Antigen (HLA) Mismatched Unrelated Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported He Huang 29 participants Est. completion 2027-10-31 1 site Stand-aloneOther conditions: Hematologic DiseaseView official trial listing → -
Recruiting NCT NCT06815003
Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning
Not yet reported City of Hope Medical Center 35 participants Est. completion 2028-10-15 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Graft Versus Host Disease, Myelodysplastic Syndrome, Myeloproliferative NeoplasmView official trial listing → -
Recruiting NCT NCT06821048
Study of CEA Targeting CAR-T (PTC13) in the Treatment of CEA-Positive Advanced Malignant Solid Tumors
Not yet reported Weijia Fang, MD 18 participants Est. completion 2027-12-01 1 site Stand-aloneOther conditions: Colorectal Cancer, Stomach Cancer, Pancreatic Cancer, Metastatic CancerView official trial listing → -
Recruiting NCT NCT06826118
Axicabtagene Ciloleucel Injection in Patients With Relapsed/Refractory Follicular Lymphoma
Not yet reported The First Affiliated Hospital of Xiamen University 30 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Lymphoma, Follicular Lymphoma, Refractory LymphomaView official trial listing → -
Recruiting NCT NCT06826430
Inaticabtagene Autoleucel Injection in the Treatment of Refractory Systemic Lupus Erythematosus-related Immune Thrombocytopenia
Not yet reported Juventas Cell Therapy Ltd. 12 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Autoimmune ThrombocytopeniaView official trial listing → -
Recruiting NCT NCT06829472
Conditioning Regimen of Melphalan-busulfan and Fludarabine: a Randomized Study of Different Dose of Melphalan
Not yet reported Shanghai Jiao Tong University School of Medicine 120 participants Est. completion 2026-12-01 2 sites Stand-aloneOther conditions: Toxicities, SurvivorshipView official trial listing → -
Recruiting NCT NCT06834282
CER-1236 in Patients With Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), and Myelofibrosis (MF)
Not yet reported CERo Therapeutics Holdings, Inc. 18 participants Est. completion 2029-12-31 5 sites Stand-aloneOther conditions: AML, Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06834529
CAR2219 CAR-T Cells for the Treatment of R/R B Cell Leukemia and Lymphoma
Not yet reported, Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 20 participants Est. completion 2027-01-31 1 site Stand-aloneOther conditions: Relapsed or Refractory B Cell Leukemia and LymphomaView official trial listing → -
Recruiting NCT NCT06838832
Novel Allogenic CD19-targeting CAR-γδT Cell Therapy (QH103E) in r/r NHL
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2028-03-01 1 site Stand-aloneOther conditions: Non-hodgkin Lymphoma,B CellView official trial listing → -
Recruiting NCT NCT06847269
CAR T CELL Therapy for Pediatric, Adolescent and Young Adult Patients With CD19-Positive Leukemia
Not yet reported St. Jude Children's Research Hospital 25 participants Est. completion 2031-04 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06859424
A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation
Not yet reported Center for International Blood and Marrow Transplant Research 358 participants Est. completion 2028-06 13 sites Stand-aloneOther conditions: AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL), Acute Leukemia (Category), MDS (Myelodysplastic Syndrome), CML (Chronic Myelogenous Leukemia), CLL (Chronic Lymphocytic Leukemia), Prolymphocyctic Leukemia, Chronic Myelomonocytic Leukemia (CMML), Myeloproliferative Neoplasm (MPN), Lymphoma, MyelofibrosisView official trial listing → -
Recruiting NCT NCT06865664
FGFR4 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory Rhabdomyosarcoma
Not yet reported National Cancer Institute (NCI) 50 participants Est. completion 2029-04-01 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Recruiting NCT NCT06869265
Thiotepa Combined With Busulfan and Fludarabine Conditioning Regimen for Haploidentical Hematopoietic Stem Cell Transplantation in Elderly Patients With High-Risk Acute Myeloid Leukemia
Not yet reported Peking University People's Hospital 56 participants Est. completion 2029-04-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), High Risk Acute Myeloid Leukemia(AML), Relapsed/Refractory Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT06871410
Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported Roswell Park Cancer Institute 26 participants Est. completion 2028-04-01 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06872333
Allo HSCT for High Risk Hemoglobinopathies
Not yet reported Masonic Cancer Center, University of Minnesota 62 participants Est. completion 2032-06-01 1 site Stand-aloneOther conditions: Graft Failure, Sickle Cell Disease, HemoglobinopathiesView official trial listing → -
Recruiting NCT NCT06874946
Nanobody-Based Anti-CD5 CAR-T for Relapsed/Refractory T-ALL/NHL
Not yet reported, Not yet reported Peking University People's Hospital 30 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, T - Cell Lymphoma, PTCLView official trial listing → -
Recruiting NCT NCT06879340
Evaluating the Safety and Efficacy of DuoCAR20.19.22-D95 in Adult Patients With Relapsed or Refractory B-cell Malignancies
Not yet reported University of Kansas Medical Center 54 participants Est. completion 2040-03 1 site Stand-aloneOther conditions: B-Cell Non-Hodgkin Lymphoma, B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT06880913
Nanobody-Based CD19/CD22 Tandem Dual CAR-T Therapy for R/R B-ALL
Not yet reported, Not yet reported Peking University People's Hospital 50 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Precursor B-Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Recruiting NCT NCT06885697
Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma
Not yet reported National Cancer Institute (NCI) 100 participants Est. completion 2044-06-01 1 site Stand-aloneOther conditions: Mesothelioma, Neoplasms, Stomach Neoplasms, Pancreatic Neoplasms, Ovarian Neoplasms, Lung Neoplasms, Thymus Neoplasms, Colonic NeoplasmsView official trial listing → -
Recruiting NCT NCT06889766
NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma
Not yet reported Centre Hospitalier Universitaire Vaudois 9 participants Est. completion 2029-06 2 sitesOther conditions: Advanced Melanoma, Melanoma Metastatic, SarcomaView official trial listing → -
Recruiting NCT NCT06897930
A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE
Not yet reported, Not yet reported AstraZeneca 150 participants Est. completion 2029-05-01 20 sites Stand-aloneOther conditions: Lupus Erythematosus, SystemicView official trial listing → -
Recruiting NCT NCT06898385
A Phase I Clinical Study of IX001 TCR-T Injection in the Treatment of Advanced Pancreatic Cancer Patients With KRAS G12V Mutation
Not yet reported Sun Yat-sen University 9 participants Est. completion 2027-09-27 1 site Stand-aloneOther conditions: Pancreatic CancerView official trial listing → -
Recruiting NCT NCT06902012
Safety and Efficacy of Early Second Infusion of Axi-cel Based on ctDNA for R/R Large B - Cell Lymphoma
Not yet reported, Not yet reported Zhujiang Hospital 15 participants Est. completion 2028-08 1 site Stand-aloneOther conditions: Relapsed/Refractory Diffuse Large B-cell LymphomaView official trial listing → -
Recruiting NCT NCT06902389
A Clinical Study of Multi-target Hi-TCR-T Cells in the Treatment of Advanced Hepatocellular Carcinoma
Not yet reported, Not yet reported Eastern Hepatobiliary Surgery Hospital 30 participants Est. completion 2028-04-07 1 site Stand-aloneOther conditions: Advanced Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT06903117
Anti-CEA CAR-T for Advanced CEA-Positive Lung Carcinoma
Not yet reported Chongqing Precision Biotech Co., Ltd 60 participants Est. completion 2028-03-31 1 site Stand-aloneOther conditions: Advanced Lung CancerView official trial listing → -
Recruiting NCT NCT06904066
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
Not yet reported National Cancer Institute (NCI) 86 participants Est. completion 2029-04-30 1 site Stand-aloneOther conditions: Malignancy, Hematologic, Neoplasms, Hematologic, Neoplasms, Hematopoietic, Blood Cancer, Hematological Neoplasms, Hematopoietic Malignancies, Dysmyelopoietic Syndromes, Hematopoetic Myelodysplasia, Myeloid Leukemia, Acute, Nonlymphoblastic Leukemia, Acute, Leukemia, Lymphocytic, AcuteView official trial listing → -
Recruiting NCT NCT06912152
MT027 in Patients With Advanced Peritoneal Malignancies or Abdominal Metastatic Solid Tumors
Not yet reported Zhejiang University 12 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: B7-H3-positive Advanced Malignant Solid Tumors Advanced Primary Peritoneal Tumors or Secondary Abdominal Metastatic Malignant Solid TumorsView official trial listing → -
Recruiting NCT NCT06916767
Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma
Not yet reported Paolo Caimi, MD 18 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Relapsed CLL, Refractory CLL, Refractory LymphomaView official trial listing → -
Recruiting NCT NCT06925464
CD7 CAR T-Cell Therapy for r/r T-cell Lymphomas
Not yet reported, Not yet reported Beijing GoBroad Hospital 36 participants Est. completion 2027-04-01 4 sites Stand-aloneOther conditions: T-Cell Non-Hodgkin Lymphoma, T-cell Lymphoma (PTCL and CTCL)View official trial listing → -
Recruiting NCT NCT06928662
Chemotherapy (Decitabine in Combination With FLAG-Ida) and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Adults With Myeloid Malignancies at High Risk of Relapse
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 36 participants Est. completion 2028-11-29 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Undifferentiated Leukemia, Mixed Phenotype Acute Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Acute Undifferentiated Leukemia, Recurrent Chronic Myelomonocytic Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Acute Undifferentiated Leukemia, Refractory Chronic Myelomonocytic Leukemia, Refractory Mixed Phenotype Acute Leukemia, Refractory Myelodysplastic Syndrome, Secondary Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT06930651
A Phase I/II Study of CAR.70-Engineered IL15-Transduced Cord Blood-Derived NK Cells With TGF-beta Receptor 2 (TGFBR2) Knock Out in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Myeloid Malignancies
Not yet reported, Not yet reported M.D. Anderson Cancer Center 42 participants Est. completion 2030-05-01 1 site Stand-aloneOther conditions: Myeloid MalignanciesView official trial listing → -
Recruiting NCT NCT06937567
CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors
Not yet reported Zhejiang University 36 participants Est. completion 2028-05-30 1 site Stand-aloneOther conditions: Biliary Tract Cancer, Colorectal Carcinoma, Gastric Cancer, Metastatic, Pancreatic Adenocarcinoma (Ductal Adenocarcinoma), Multiple CancerView official trial listing → -
Recruiting NCT NCT06940297
Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported Mayo Clinic 44 participants Est. completion 2031-08-15 1 site Stand-aloneOther conditions: Recurrent Multiple Myeloma, Refractory Multiple MyelomaView official trial listing → -
Recruiting NCT NCT06945523
Clinical Study on Chimeric Antigen Receptor T Lymphocyte (CAR-T) Targeting CEA for the Treatment of CEA - Positive Advanced Lung Cancer
Not yet reported Chongqing Precision Biotech Co., Ltd 60 participants Est. completion 2028-04-30 1 site Stand-aloneOther conditions: Advanced Lung CancerView official trial listing → -
Recruiting NCT NCT06946225
ACTengine® IMA203 Combined With mRNA-4203
Not yet reported Immatics US, Inc. 15 participants Est. completion 2029-08 4 sites Stand-aloneOther conditions: Cutaneous Melanoma, Synovial SarcomaView official trial listing → -
Recruiting NCT NCT06947460
CD19-BCMA CART Cell Therapy for Refractory SLE-LN, SSc, and pSS-PAH
Not yet reported, Not yet reported Beijing GoBroad Hospital 45 participants Est. completion 2026-07-31 1 site Stand-aloneOther conditions: Refractory Lupus Nephritis, Systemic Sclerosis, Primary Sjogren's Syndrome Combined With Pulmonary Hypertension, Other Autoimmune Diseases (AID)View official trial listing → -
Recruiting NCT NCT06947473
Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.
Not yet reported, Not yet reported Beijing GoBroad Hospital 45 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Refractory Lupus Nephritis, Systemic Sclerosis, Primary Sjogren's Syndrome Combined With Pulmonary HypertensionView official trial listing → -
Recruiting NCT NCT06961357
Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma
Not yet reported, Not yet reported H. Lee Moffitt Cancer Center and Research Institute 36 participants Est. completion 2030-05 1 site Stand-aloneOther conditions: MelanomaView official trial listing → -
Recruiting NCT NCT06961669
Intravenous Autologous CD19 CAR-T Cells for R/ R MM, B-ALL, and B-Cell Lymphoma
Not yet reported Anhui Provincial Hospital 18 participants Est. completion 2028-08-31 1 site Stand-aloneOther conditions: Lymphoblastic Leukemia, Relapsed or Refractory Multiple Myeloma (RRMM)View official trial listing → -
Recruiting NCT NCT06992583
Targeted Anti-CEA CAR-T Immunotherapy for Advanced Lung Cancer
Not yet reported Chongqing Precision Biotech Co., Ltd 60 participants Est. completion 2028-04-30 1 site Stand-aloneOther conditions: Advanced Lung CancerView official trial listing → -
Recruiting NCT NCT06996119
Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant
Not yet reported City of Hope Medical Center 15 participants Est. completion 2027-05-25 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Graft Versus Host Disease, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT06996132
Bispecific Antibody-Based Salvage Therapy Followed by CAR-T ± ASCT in R/R Aggressive B-Cell Lymphoma
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 25 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Relapsed or Refractory Aggressive B-cell LymphomaView official trial listing → -
Recruiting NCT NCT06997471
Phase I Trial on the Safety of Delayed Infusion of a Naïve T Cell-Depleted Hematopoietic Graft With Memory T Cells in Solid Organ Transplant Recipients
Not yet reported Francisco Hernández Oliveros 10 participants Est. completion 2028-06 1 site Stand-aloneOther conditions: Solid Organ Transplant Complications, Solid Organ Transplant Recipients, Solid Organ Transplant RejectionView official trial listing → -
Recruiting NCT NCT07003555
Dual-target BCMA-CD19 CAR-T Cell Therapy for RR/MM With Extramedullary Infiltration
Not yet reported Beijing GoBroad Hospital 18 participants Est. completion 2027-06-25 1 site Stand-aloneOther conditions: Relapsed or Refractory Multiple Myeloma (RRMM)View official trial listing → -
Recruiting NCT NCT07003568
Dual-target BCMA-GPRC5D CAR-T Cell Therapy for RR/MM With Extramedullary Infiltration
Not yet reported Beijing GoBroad Hospital 18 participants Est. completion 2027-06-25 1 site Stand-aloneOther conditions: Relapsed or Refractory Multiple Myeloma (RRMM)View official trial listing → -
Recruiting NCT NCT07004647
MT027 Cell Injection in Patients With Advanced Primary or Secondary Peritoneal Tumors
Not yet reported Ruijin Hospital 10 participants Est. completion 2028-11-30 1 site Stand-aloneOther conditions: Peritoneal TumorView official trial listing → -
Recruiting NCT NCT07008885
BCOR and ZC3H12 Genes Knock-out CD19-targeting CAR-T Cell Therapy in r/r B-ALL
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2027-05-31 2 sites Stand-aloneOther conditions: Acute Lymphocytic LeukemiaView official trial listing → -
Recruiting NCT NCT07009002
BCOR and ZC3H12 Genes Knock-out CD19-targeting CAR-T Cell Therapy in r/r B Cell Lymphoma
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2027-05-31 1 site Stand-aloneOther conditions: B Cell LymphomaView official trial listing → -
Recruiting NCT NCT07010523
Anti-Mesothelin CAR-T Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors
Not yet reported First Affiliated Hospital of Zhejiang University 24 participants Est. completion 2027-10-14 1 site Stand-aloneOther conditions: Mesothelin-positive Advanced Malignant Solid TumorsView official trial listing → -
Recruiting NCT NCT07011004
A Study of Natural Killer Cells in Combination With Atezolizumab in People With Acute Myelogenous Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 18 participants Est. completion 2028-05 7 sites Stand-aloneOther conditions: Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, in RelapseView official trial listing → -
Recruiting NCT NCT07015242
A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 65 participants Est. completion 2028-12-10 40 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Recruiting NCT NCT07022197
Safety and Efficacy of BAFF-R CART for Refractory Neuroimmune Diseases
Not yet reported, Not yet reported Tianjin Medical University General Hospital 27 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Chronic Inflammatory Demyelinating Polyradiculoneuropathy, NMO Spectrum Disorder, Myasthenia Gravis, Idiopathic Inflammatory MyopathiesView official trial listing → -
Recruiting NCT NCT07022964
CD5 CAR T-Cell Therapy for r/r T-cell Lymphomas
Not yet reported, Not yet reported Beijing GoBroad Hospital 36 participants Est. completion 2028-06-01 3 sites Stand-aloneOther conditions: T-Cell Non-Hodgkin Lymphoma, T-cell Lymphoma (PTCL and CTCL)View official trial listing → -
Recruiting NCT NCT07025824
Evaluation of Treosulfan Versus Melphalan Conditioning Followed by PTCy in Patients With AML and MDS Undergoing Allogeneic Transplantation
Not yet reported Technische Universität Dresden 220 participants Est. completion 2029-09 17 sites Stand-aloneOther conditions: AML - Acute Myeloid Leukemia, MDS (Myelodysplastic Syndrome)View official trial listing → -
Recruiting NCT NCT07032129
Sequential CAR-T Cells Targeting BCMA/GPRC5D in Patients With Relapsed/ Refractory Multiple Myeloma
Not yet reported, Not yet reported Essen Biotech 60 participants Est. completion 2028-12-28 1 site Stand-aloneOther conditions: Multiple Myeloma, Multiple Myeloma in Relapse, Multiple Myeloma Progression, Multiple Myeloma, RefractoryView official trial listing → -
Recruiting NCT NCT07036250
Clinical Study of U32 in Patients With Acute Myeloid Leukemia
Not yet reported, Not yet reported Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd 20 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukaemiaView official trial listing → -
Recruiting NCT NCT07045909
Efficacy and Safety of Anitocabtagene Autoleucel in Participants With Newly Diagnosed Multiple Myeloma (GEM-AnitoFIRST)
Not yet reported PETHEMA Foundation 30 participants Est. completion 2030-03-31 10 sites Stand-aloneOther conditions: De Novo Multiple Myeloma, Anitocabtagene AutoleucelView official trial listing → -
Recruiting NCT NCT07046078
Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer
Not yet reported Fred Hutchinson Cancer Center 20 participants Est. completion 2029-06-30 1 site Stand-aloneOther conditions: Acute Leukemia of Ambiguous Lineage, Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT07052565
CAR-T Cells Therapy for Patients With Autoimmune Diseases
Not yet reported Anhui Provincial Hospital 18 participants Est. completion 2028-11-01 1 site Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Recruiting NCT NCT07059975
UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML
Not yet reported Baylor College of Medicine 36 participants Est. completion 2031-08 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Pediatric AMLView official trial listing → -
Recruiting NCT NCT07061938
Study to Assess Safety, Efficacy and Persistence of ACE1831, in Subjects With IgG4-Related Disease
Not yet reported, Not yet reported Acepodia Biotech, Inc. 34 participants Est. completion 2029-09-20 11 sites Stand-aloneOther conditions: IgG4 Related DiseaseView official trial listing → -
Recruiting NCT NCT07066397
A Phase 1 Study of FIT-CD19-CAR-T Cells in R/R B-ALL
Not yet reported TriArm Therapeutics (Taiwan) Limited 12 participants Est. completion 2041-04-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT07066982
Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas
Not yet reported, Not yet reported Essen Biotech 60 participants Est. completion 2028-12-28 1 site Stand-aloneOther conditions: Sarcoma, Sarcoma, Kaposi, Sarcoma, Ewing, Sarcoma,Soft Tissue, Sarcoma of Bone and Connective Tissue, Sarcoma, Synovial, Sarcoma Metastatic, Sarcomas, Germinoblastic, Sarcoma of BoneView official trial listing → -
Recruiting NCT NCT07066995
Mesothelin and Claudin 18.2 Dual-Target CAR-T Therapy in Advanced Pancreatic Cancer
Not yet reported, Not yet reported Essen Biotech 60 participants Est. completion 2028-12-28 1 site Stand-aloneOther conditions: Pancreatic Cancer, Pancreatic Carcinoma, Pancreatic Cancer Non-resectable, Pancreatic Cancer Stage IVView official trial listing → -
Recruiting NCT NCT07067255
Sequential CD146 and GPC3 CAR-T Cell Therapy in Advanced Ovarian Cancer
Not yet reported, Not yet reported Essen Biotech 80 participants Est. completion 2029-12-28 1 site Stand-aloneOther conditions: Ovarian Cancer, Ovarian Carcinoma, Ovarian Sarcoma, Ovarian Cancer Stage IVView official trial listing → -
Recruiting NCT NCT07072234
Phase I Study of Allogeneic Transforming Growth Factor-beta Receptor Type 2 Knockout CD70 CAR NK Cells in Treatment Refractory Clear Cell Renal Cell Carcinoma
Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2030-02-01 1 site Stand-aloneOther conditions: Clear Cell Carcinoma, Phase 1, Growth FactorView official trial listing → -
Recruiting NCT NCT07072494
CD19 CAR-T Cell Infusion as Consolidation Therapy in Adolescent and Adult Patients With Acute B-ALL Ineligible for Allogeneic HSCT: A Clinical Study
Not yet reported, Not yet reported Zhujiang Hospital 30 participants Est. completion 2027-08-19 2 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT07077512
Relmacabtagene Autoleucel Combined With Sintilimab for Relapsed/Refractory B-cell Lymphoma
Not yet reported Sun Yat-sen University 30 participants Est. completion 2027-07-15 3 sites Stand-aloneOther conditions: Large B Cell Diffuse Lymphoma, Mantle Cell Lymphoma (MCL), Follicular Lymphoma ( FL)View official trial listing → -
Recruiting NCT NCT07085104
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
Not yet reported Allogene Therapeutics 66 participants Est. completion 2032-10 17 sites Stand-aloneOther conditions: Systemic Lupus Erythematosus (With and Without Nephritis), Idiopathic Inflammatory Myopathy, Systemic SclerosisView official trial listing → -
Recruiting NCT NCT07085559
Safety and Efficacy of Metabolically Armed BCMA CAR-T Cells (Meta10-BCMA) in the Treatment of r/r Plasma Cell Neoplasms Clinical Research
Not yet reported Anhui Provincial Hospital 36 participants Est. completion 2027-10-15 1 site Stand-aloneOther conditions: Multiple Myeloma (MM), Plasma Cell Leukemia (PCL), AL Amyloidosis (AL)View official trial listing → -
Recruiting NCT NCT07087002
GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults
Not yet reported Stanford University 18 participants Est. completion 2027-08 1 site Stand-aloneOther conditions: Medulloblastoma, Central Nervous System Embryonal Tumor, Refractory Medulloblastoma, Recurrent Medulloblastoma, Pediatric Brain Tumor, Embryonal Tumor With Multilayered Rosettes (ETMR), Pineoblastoma, Atypical Teratoid/Rhabdoid Tumor (ATRT) of the CNS, CNS Neuroblastoma, FOXR2-activatedView official trial listing → -
Recruiting NCT NCT07093073
Clinical Study of U01(ssCART-19) in Patients With B-Cell Lymphoma
Not yet reported Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd 30 participants Est. completion 2029-01-31 1 site Stand-aloneOther conditions: B Cell LymphomaView official trial listing → -
Recruiting NCT NCT07093411
Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported Beijing GoBroad Hospital 48 participants Est. completion 2028-12 3 sites Stand-aloneOther conditions: B-cell Non-Hodgkin Lymphoma Recurrent B-cell Non-Hodgkin Lymphoma RefractoryView official trial listing → -
Recruiting NCT NCT07095075
A Study of LUCAR-DKS1 in Subjects With Relapsed/Refractory Autoimmune Diseases
Not yet reported Nanjing Legend Biotech Co. 36 participants Est. completion 2029-12-31 5 sites Stand-aloneOther conditions: Relapsed/Refractory Autoimmune DiseasesView official trial listing → -
Recruiting NCT NCT07097207
Efficacy and Safety of CD19CD20-CAR.p40-T in B-cell Lymphoma
Not yet reported, Not yet reported Shenzhen University General Hospital 20 participants Est. completion 2026-09-30 1 site Stand-aloneOther conditions: Relapsed/Refractory B-cell LymphomaView official trial listing → -
Recruiting NCT NCT07100067
LCAR-F33S in Treatment of Relapsed/Refractory Multiple Myeloma
Not yet reported Nanjing Legend Biotech Co. 35 participants Est. completion 2029-11-20 4 sites Stand-aloneOther conditions: Relapsed/Refractory Multiple Myeloma(MM)View official trial listing → -
Recruiting NCT NCT07101588
Ruxolitinib-Decitabine Intensified Conditioning Regimen for AML: A Randomized Trial
Not yet reported Chinese PLA General Hospital 200 participants Est. completion 2028-12-30 1 siteOther conditions: Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)View official trial listing → -
Recruiting NCT NCT07104799
Momelotinib During and After HCT in Myelofibrosis
Not yet reported Massachusetts General Hospital 28 participants Est. completion 2030-01 1 site Stand-aloneOther conditions: Myelofibrosis, Hematopoietic Cell Transplantation (HCT)View official trial listing → -
Recruiting NCT NCT07105735
RN1201 Injection for Autoimmune Diseases Refractory to Standard Therapies
Not yet reported The First Affiliated Hospital with Nanjing Medical University 18 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Autoimmune Diseases Refractory to Standard TherapiesView official trial listing → -
Recruiting NCT NCT07106749
CD180 CART for Relapsed or Refractory CD180 Positive Hematologic Malignancies
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 12 participants Est. completion 2030-06-28 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia/LymphomaView official trial listing → -
Recruiting NCT NCT07106814
Safety and Efficacy of Metabolically Armed Tumor-lnfiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors
Not yet reported Anhui Provincial Hospital 36 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT07108530
Efficacy of Integrated Induction-Consolidation Chemotherapy and Transplantation for Adult Acute Myeloid Leukemia: Multicenter Study
Not yet reported Shanxi Bethune Hospital 50 participants Est. completion 2027-08-06 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07109518
uCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 12 participants Est. completion 2030-06-28 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), T Lymphoblastic Leukemia/LymphomaView official trial listing → -
Recruiting NCT NCT07115745
A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 125 participants Est. completion 2030-08-16 28 sites Stand-aloneOther conditions: Refractory Autoimmune DiseasesView official trial listing → -
Recruiting NCT NCT07116057
MOv19-BBz CAR T Cells in FRa+ Cancers
Not yet reported University of Pennsylvania 10 participants Est. completion 2040-10 1 site Stand-aloneOther conditions: Metastatic Non Small Cell Lung Cancer, Recurrent Lung Non-Small Cell CarcinomaView official trial listing → -
Recruiting NCT NCT07123545
Autologous Neoantigen-Specific T-Cell Therapy for Advanced Hepatocellular Carcinoma
Not yet reported, Not yet reported Zhejiang University 20 participants Est. completion 2029-07-31 1 site Stand-aloneOther conditions: Advanced Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT07139067
Phase I Clinical Study of YK1101 Injection for the Treatment of Advanced Solid Tumors
Not yet reported Peking University 10 participants Est. completion 2028-07-01 2 sites Stand-aloneOther conditions: Advanced Solid Tumor CancerView official trial listing → -
Recruiting NCT NCT07139509
Allogeneic UCB-derived, Dual-targeting BCMA/CD19 CAR-T for Relapsed/Refractory Multiple Myeloma
Not yet reported Xi'an No.3 Hospital 18 participants Est. completion 2028-12-30 1 site Stand-aloneOther conditions: Relapsed/Refractory Multiple Myeloma(MM)View official trial listing → -
Recruiting NCT NCT07144462
A Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of NEUK203-215 Injection in Adult Chinese Patients With Relapsed/Refractory Autoimmune Diseases
Not yet reported Neukio Biotherapeutics (Shanghai) Co., Ltd. 8 participants Est. completion 2027-01-14 1 site Stand-aloneOther conditions: AutoimmuneView official trial listing → -
Recruiting NCT NCT07145450
Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC
Not yet reported, Not yet reported Anocca AB 96 participants Est. completion 2030-07-31 10 sitesOther conditions: PDACView official trial listing → -
Recruiting NCT NCT07148791
Exploratory Study of Anti-BCMA-CD19 CAR-T Cell Therapy in Relapsed or Refractory IgG4-Related Disease
Not yet reported Chinese PLA General Hospital 9 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: IgG4 Related Disease, B-cell Mediated Autoimmune DisordersView official trial listing → -
Recruiting NCT NCT07149857
A Study to Evaluate Efficacy and Safety of Ciltacabtagene Autoleucel
Not yet reported Janssen Research & Development, LLC 60 participants Est. completion 2029-04-06 20 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Recruiting NCT NCT07153068
SupCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 12 participants Est. completion 2030-06-28 1 site Stand-aloneOther conditions: T Lymphoblastic Leukemia/Lymphoma, Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT07162038
Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation
Not yet reported National Cancer Institute (NCI) 155 participants Est. completion 2034-10-01 1 site Stand-aloneOther conditions: Hematologic Malignancies, Hematologic NeoplasmsView official trial listing → -
Recruiting NCT NCT07172958
Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE)
Not yet reported Children's National Research Institute 18 participants Est. completion 2044-12 2 sites Stand-aloneObstructive sleep apnea Other conditions: Ewing Sarcoma, Neuroblastoma, Wilms TumorView official trial listing → -
Recruiting NCT NCT07174427
Multi-center Study of TBI-1301 (INN: Mipetresgene Autoleucel; Mip-cel) in Patients With NY-ESO-1 Positive Synovial Sarcoma
Not yet reported Takara Bio Inc. 5 participants Est. completion 2032-03 3 sites Stand-aloneOther conditions: Synovial SarcomasView official trial listing → -
Recruiting NCT NCT07179692
CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid Tumors
Not yet reported Chongqing Precision Biotech Co., Ltd 108 participants Est. completion 2028-05-31 1 site Stand-aloneOther conditions: Lung Cancer, Gastric Cancer, Colon Cancer, Rectal Cancer, Esophageal Cancer, Pancreas CancerView official trial listing → -
Recruiting NCT NCT07203404
A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases.
Not yet reported Nanjing Bioheng Biotech Co., Ltd. 96 participants Est. completion 2028-07-23 1 site Stand-aloneOther conditions: SLE, LN, ANCA Associated Vasculitis, ANCA-Associated Glomerulonephritis, Anti-GBM Disease, MN, SSc, IIM, IgA NephropathyView official trial listing → -
Recruiting NCT NCT07214688
Fludarabine and Intermediate-dose TBI Followed by PTCy in Patients Undergoing Allo Transplant for Heme Malignancies
Not yet reported Hackensack Meridian Health 209 participants Est. completion 2032-01 3 sites Stand-aloneOther conditions: Allogeneic Stem Cell Transplant RecipientView official trial listing → -
Recruiting NCT NCT07220993
Novel Unedited Allo Cell Therapy For High Risk T-Cell Malignancies Using CD7-Specific Car T Cells
Not yet reported Baylor College of Medicine 27 participants Est. completion 2043-12 2 sites Stand-aloneOther conditions: T-cell Acute Lymphoblastic Lymphoma, T-non-Hodgkin Lymphoma, T-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT07222735
Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas
Not yet reported St. Jude Children's Research Hospital 42 participants Est. completion 2031-11-05 1 site Stand-aloneObstructive sleep apnea Other conditions: Sarcoma, Childhood Soft Tissue Sarcoma, Ewing SarcomaView official trial listing → -
Recruiting NCT NCT07223021
A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 130 participants Est. completion 2028-10 6 sites Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT07225439
Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)
Not yet reported Paolo Caimi, MD 15 participants Est. completion 2027-12 2 sites Stand-aloneOther conditions: Non Hodgkin Lymphoma, B-cell Non Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, High-grade B-cell Lymphoma, Primary Mediastinal Large B Cell Lymphoma, Follicular Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone Lymphoma, Mantle Cell LymphomaView official trial listing → -
Recruiting NCT NCT07227571
Genetically Engineered Cells (FH-FOLR1 ST CAR T Cells) for the Treatment of Advanced Refractory or Recurrent/Progressive Osteosarcoma, FIERCe Trial
Not yet reported Fred Hutchinson Cancer Center 30 participants Est. completion 2044-01-31 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Recruiting NCT NCT07228273
Induction and Consolidation With Fludarabine, Cytarabine, Idarubicin, and Venetoclax for the Treatment of Acute Myeloid Leukemia
Not yet reported OHSU Knight Cancer Institute 102 participants Est. completion 2029-08-24 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Recruiting NCT NCT07228624
Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes
Not yet reported Fred Hutchinson Cancer Center 50 participants Est. completion 2030-09-01 1 site Stand-aloneOther conditions: Myelodysplastic/Myeloproliferative Neoplasm, Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Recruiting NCT NCT07241468
An Exploratory Clinical Study on the Safety and Efficacy of Anti-CD19/BCMA U CAR-T Cells in the Treatment of Relapsed/Refractory Immune-mediated Kidney Disease
Not yet reported Changhai Hospital 36 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Relapsed/Refractory Immune Nephropathy, Relapsed/Refractory Immune-mediated Kidney DiseaseView official trial listing → -
Recruiting NCT NCT07242417
TC-G203 for Patients With GPC3-Positive Advanced Solid Tumors
Not yet reported Beijing GoBroad Hospital 30 participants Est. completion 2027-11-01 2 sites Stand-aloneOther conditions: Solid Cancer, GPC3 Positive Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07246096
Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases
Not yet reported Changhai Hospital 60 participants Est. completion 2028-07-20 1 site Stand-aloneOther conditions: Autoimmune Diseases, Systemic Lupus Erythematosus, Systemic Sclerosis, Primary Sjögren Syndrome, Rheumatoid Arthritis, Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisView official trial listing → -
Recruiting NCT NCT07246304
TC-D101 Cell Therapy for Patients With DLL3-Positive SCLC
Not yet reported TCRCure Biopharma Ltd. 24 participants Est. completion 2028-11-30 1 site Stand-aloneOther conditions: Small Cell Lung Cancer ( SCLC ), CAR-T Cell TherapyView official trial listing → -
Recruiting NCT NCT07247396
CEA CAR-T Therapy After Cytoreduction in Colorectal Cancer Patients With Peritoneal Metastases
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 12 participants Est. completion 2027-10-31 1 site Stand-aloneOther conditions: Peritoneal Metastases From Colorectal CancerView official trial listing → -
Recruiting NCT NCT07250386
A Study of CEA-Targeted CAR-T Therapy in Patients With CEA-Positive Advanced Solid Tumors
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 48 participants Est. completion 2028-09-30 1 site Stand-aloneOther conditions: NSCLC (Advanced Non-small Cell Lung Cancer), Breast CancerView official trial listing → -
Recruiting NCT NCT07252050
Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease
Not yet reported, Not yet reported Arkansas Children's Hospital Research Institute 24 participants Est. completion 2029-11-19 4 sites Stand-aloneOther conditions: Sickle Cell Disease, Hematopoetic Stem Cell Transplant, Haploidentical Hematopoietic Stem Cell Transplant, Haploidentical Stem Cell Transplantation, Graft FailureView official trial listing → -
Recruiting NCT NCT07257419
CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma
Not yet reported St. Jude Children's Research Hospital 70 participants Est. completion 2035-12 1 site Stand-aloneOther conditions: Relapsed Pediatric ALL, Hematopoietic Cell Transplantation, Hematologic MalignancyView official trial listing → -
Recruiting NCT NCT07259070
Multicenter, Single-Arm Exploratory Phase I Clinical Study (Assessment of Safety and Efficacy) of Fully Human BAFF-R Chimeric Antigen Receptor T-Cell Injection in Relapsed/Refractory BAFF-R-Positive B-Cell Lymphoma
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 20 participants Est. completion 2029-11-28 1 siteOther conditions: DLBCL, CLL, FL, MCL, WM, MZLView official trial listing → -
Recruiting NCT NCT07266181
Safety and Efficacy of CD19 Chimeric Antigen Receptor T-Cell (CAR-T) in the Treatment of Refractory Membranous Nephropathy
Not yet reported The First Affiliated Hospital of Air Force Medicial University 5 participants Est. completion 2028-07-31 1 siteOther conditions: Refractory Membranous NephropathyView official trial listing → -
Recruiting NCT NCT07275736
A Study of CNCT19 in the Treatment of Relapsed or Refractory Neurological Autoimmune Diseases
Not yet reported Juventas Cell Therapy Ltd. 18 participants Est. completion 2029-06-01 1 site Stand-aloneOther conditions: Neurological Autoimmune DiseasesView official trial listing → -
Recruiting NCT NCT07283315
Exploratory Clinical Study of Second-generation CD19/BCMA Chimeric Antigen Receptor NK Cell Injection in Treating Paediatric B Cell-related Autoimmune Diseases
Not yet reported The Children's Hospital of Zhejiang University School of Medicine 12 participants Est. completion 2029-12-30 1 site Stand-aloneOther conditions: Paediatric B Cell-related Autoimmune Diseases, Autoimmune Diseases, CARView official trial listing → -
Recruiting NCT NCT07284433
Study of Allo-QuadCAR01-T, an Allogeneic CAR-T Targeting CD19/CD20, in Patients With Relapsed or Refractory B-Cell Malignancies
Not yet reported, Not yet reported AvenCell Therapeutics, Inc. 178 participants Est. completion 2029-11-02 13 sites Stand-aloneOther conditions: Lymphoma Diffuse Large B-cell, Leukemia and Lymphoma, Leukemia Relapse, Lymphoma Receiving CAR-T TherapyView official trial listing → -
Recruiting NCT NCT07284641
Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)
Not yet reported Paul Szabolcs 25 participants Est. completion 2031-02-01 1 siteOther conditions: Common Variable Immunodeficiency (CVID), Primary Immune Regulatory Disorder, Immune Dysregulation, DiGeorge Syndrome, STAT 1 Gain of Function, STAT 3 Gain of Function, Hypomorphic RAG1 Deficiency, CD40 Ligand Deficiency, Mendelian Susceptibility to Mycobacterial Disease, GATA2 Associated Immunodeficiency, CD40 Deficiency, Hypomorphic RAG2 Deficiency, Immune Dysregulation Polyendocrinopathy Enteropathy X-Linked Syndrome, Omenn Syndrome, Chronic Granulomatous DiseaseView official trial listing → -
Recruiting NCT NCT07288073
TIL Therapy in cSCC and MCC
Not yet reported Karam Khaddour, MD, MS 14 participants Est. completion 2029-06-29 1 site Stand-aloneOther conditions: Cutaneous Squamous Cell Carcinoma, Merkel Cell Carcinoma, Metastatic Cutaneous Squamous Cell Carcinoma, Skin CancerView official trial listing → -
Recruiting NCT NCT07297173
Phase 1 Study of Chemotherapy Plus HLA-mismatched GPBMC Infusion Bridging to Allo-HSCT for R/R Leukemia
Not yet reported Beijing 302 Hospital 5 participants Est. completion 2030-12-01 1 site Stand-aloneOther conditions: Relapsed Leukemia, Refractory LeukemiaView official trial listing → -
Recruiting NCT NCT07297667
GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours
Not yet reported Canadian Cancer Trials Group 30 participants Est. completion 2033-09-01 3 sites Stand-aloneOther conditions: Alveolar Soft Part Sarcoma, Renal Cell Carcinoma, Triple Negative Breast CancerView official trial listing → -
Recruiting NCT NCT07304154
A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases
Not yet reported Kite, A Gilead Company 52 participants Est. completion 2029-06 8 sites Stand-aloneOther conditions: Chronic Inflammatory Demyelinating Polyneuropathy, Myasthenia Gravis, Multiple SclerosisView official trial listing → -
Recruiting NCT NCT07328503
CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 20 participants Est. completion 2031-01-31 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, B-AllView official trial listing → -
Recruiting NCT NCT07331272
A Study of LUCAR-G79D in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus (r/r SLE) and Idiopathic Inflammatory Myopathies (r/r IIM)
Not yet reported Nanjing Legend Biotech Co. 38 participants Est. completion 2030-01-31 5 sites Stand-aloneOther conditions: Systemic Lupus Erythematosus (SLE), Idiopathic Inflammatory Myopathies(IIM)View official trial listing → -
Recruiting NCT NCT07333261
Study of BMS-986453 in Newly Diagnosed Multiple Myeloma
Not yet reported Susan Bal 25 participants Est. completion 2041-12 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Recruiting NCT NCT07337785
CD19/BCMA-Targeted UCAR-T for Patients With Neurological Autoimmune Diseases
Not yet reported Tongji Hospital 36 participants Est. completion 2028-11-01 1 site Stand-aloneOther conditions: Relapsing or Refractory Multiple Sclerosis (MS), Myasthenia Gravis (MG), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Autoimmune Encephalitis (AE)View official trial listing → -
Recruiting NCT NCT07349160
Safety and Efficacy of Metabolically Armed Tumor-Infiltrating Lymphocytes (Meta10-TIL) for the Treatment of Advanced Solid Tumors
Not yet reported Cancer Institute and Hospital, Chinese Academy of Medical Sciences 36 participants Est. completion 2028-01-20 1 site Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT07358260
B7-H3.CD28Z.CART in Solid Tumors
Not yet reported Robbie Majzner 40 participants Est. completion 2031-12-31 1 site Stand-aloneOther conditions: Pediatric Solid Tumor, NeuroblastomaView official trial listing → -
Recruiting NCT NCT07368270
Safety and Efficacy Study of Anti-PD1 Armored CD19 CAR-T Cells in Adult Subjects With Relapsed or Refractory Diffuse Large B-cell Lymphoma
Not yet reported Jiangsu Topcel-KH Pharmaceutical Co., Ltd. 30 participants Est. completion 2029-01 1 site Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Recruiting NCT NCT07369492
Safety and Efficacy Study of BAFF-R CAR-T Cells in Adult Subjects With CD19-Negative Relapsed or Refractory B-Cell Lymphoma
Not yet reported Jiangsu Topcel-KH Pharmaceutical Co., Ltd. 30 participants Est. completion 2029-01 1 site Stand-aloneOther conditions: B-cell LymphomaView official trial listing → -
Recruiting NCT NCT07390539
B7-H3.CD28Z.CART in CNS Neoplasms
Not yet reported Robbie Majzner 70 participants Est. completion 2032-08-31 2 sites Stand-aloneOther conditions: Central Nervous System Neoplasms, Brain Tumor, Brain Tumor, Recurrent, Brain Tumor, Pediatric, Brain Tumor Adult, Medulloblastoma, Medulloblastoma, Childhood, Medulloblastoma, Adult, Medulloblastoma Recurrent, Ependymoma, Atypical Teratoid/Rhabdoid Tumor, Embryonal Tumor With Multilayered Rosettes, Pineoblastoma, Leptomeningeal DiseaseView official trial listing → -
Recruiting NCT NCT07396480
Fludarabine Plus Melphalan Versus Addition of Venetoclax to Fludarabine/Melphalan Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in AML/MDS Patients Aged > 50 Years: a Multicenter, Randomized, Phase 3 Trial
Not yet reported First Affiliated Hospital of Zhejiang University 186 participants Est. completion 2030-06-30 18 sites Stand-aloneOther conditions: Venentoclax, Myeloid Malignancies, Conditioning, ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION, Acute Myeloid Leucemia, Myeldysplastic Syndrome (MDS)View official trial listing → -
Recruiting NCT NCT07399769
Efficacy and Safety of MSLN CAR-T in Advanced Malignant Tumors
Not yet reported, Not yet reported Shenzhen University General Hospital 20 participants Est. completion 2027-01-30 1 site Stand-aloneOther conditions: Advanced Solid Malignant Tumors (With Positive Expression of MSLN in Tumor Tissue)View official trial listing → -
Recruiting NCT NCT07410494
Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors
Not yet reported, Not yet reported Essen Biotech 85 participants Est. completion 2028-12-28 1 site Stand-aloneOther conditions: Cancer, Breast Cancer, Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer (Locally Advanced or Metastatic), Prostate Cancer - Recurrent, Pancreatic Ductal Adenocarcinoma (PDAC), Ovarian Cancer, Glioblastoma, Melanoma (Skin Cancer), Acute Myeloid Leukemia (AML), Non Hodgkin Lymphoma, Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma, Liver CancerView official trial listing → -
Recruiting NCT NCT07410676
EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors
Not yet reported, Not yet reported Essen Biotech 83 participants Est. completion 2029-12-21 1 site Stand-aloneOther conditions: Cancer, Sarcoma, Leukaemia, Breast Cancer (Locally Advanced or Metastatic), Lung Cancer (Diagnosis), Colorectal Cancer, Melanoma (Skin Cancer), Bladder Cancer, Kidney Cancer, Pancreatic Cancer Metastatic, Liver Cancer (Primary and Metastatic), Ovarian Cancer, Esophageal Cancer, Glioblastoma, Non-Melanoma Skin CancerView official trial listing → -
Recruiting NCT NCT07411599
Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial")
Not yet reported, Not yet reported M.D. Anderson Cancer Center 28 participants Est. completion 2030-11-15 1 site Stand-aloneOther conditions: Colorectal Cancer, Peritoneal Metastases, CarcinomatosisView official trial listing → -
Recruiting NCT NCT07416682
CAR BCMA-70 CAR-T Cells for the Treatment of High-risk Plasma Cell Neoplasms
Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 20 participants Est. completion 2028-01-30 1 site Stand-aloneOther conditions: High-risk Plasma Cell NeoplasmsView official trial listing → -
Recruiting NCT NCT07428993
Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma
Not yet reported St. Jude Children's Research Hospital 41 participants Est. completion 2035-12 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Recruiting NCT NCT07441291
CD19 CAR-T vs DLI for Post-HSCT MRD in Ph- ALL: A RCT
Not yet reported Peking University People's Hospital 70 participants Est. completion 2028-12-30 1 site Stand-aloneOther conditions: B ALL, Allogenetic Hematopoietic Stem Cell Transplantation, MRD-positiveView official trial listing → -
Recruiting NCT NCT07444632
Phase1 Basket Trial Of CAR.70-Engineered IL15-Transduced With TGFBR2 Knock Out Cord Blood-Derived NK Cells For Relapsed/Refractory Lymphoid Malignancies
Not yet reported M.D. Anderson Cancer Center 60 participants Est. completion 2032-09-30 1 site Stand-aloneOther conditions: Lymphoid, Hodgkin LymphomaView official trial listing → -
Recruiting NCT NCT07454226
ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 92 participants Est. completion 2030-03-01 1 site Stand-aloneOther conditions: Ph-Like, Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT07464951
CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Stephan Grupp MD PhD 30 participants Est. completion 2030-05-14 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT07467863
Dual-Target CAR-NK Cells Directed Against MSLN, EGFR, or HER2 in Advanced NSCLC
Not yet reported, Not yet reported Beijing Biotech 48 participants Est. completion 2028-02-17 1 site Stand-aloneOther conditions: Non-Small Cell Lung Cancer, Advanced/Metastatic NSCLCView official trial listing → -
Recruiting NCT NCT07473167
Study of Safety and Efficacy of TC011 in the Relapsed/Refractory Large B Cell Non-Hodgkin Lymphoma Patients
Not yet reported, Not yet reported TICAROS Co., Ltd. 98 participants Est. completion 2028-03-10 1 site Stand-aloneOther conditions: Relapsed Large B-cell Lymphoma, Refractory Large B-cell Lymphoma, Diffuse Large B-cell Lymphoma (DLBCL), High-grade B-cell Lymphoma (HGBL), Transformed Follicular Lymphoma (TFL), Primary Mediastinal Large B-cell Lymphoma (PMBCL)View official trial listing → -
Recruiting NCT NCT07477912
Anti BCMA CAR- T Cell Therapy for Adults With Relapsed or Refractory Multiple Myeloma
Not yet reported, Not yet reported Minsk Scientific-Practical Center for Surgery, Transplantation and Hematology 30 participants Est. completion 2030-02-01 1 site Stand-aloneOther conditions: Multiple Myeloma RefractoryView official trial listing → -
Recruiting NCT NCT07480213
Adaptive Phase 1/2 Study of Dual-Target CAR-NK Cells in Relapsed/Refractory Small Cell Lung Cancer (SCLC)
Not yet reported, Not yet reported Beijing Biotech 60 participants Est. completion 2028-04-17 1 site Stand-aloneOther conditions: Small Cell Lung Cancer (SCLC), Relapsed/Refractory SCLC, SCLC, Extensive StageView official trial listing → -
Recruiting NCT NCT07480928
Dual-Targeting CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma
Not yet reported, Not yet reported Beijing Biotech 42 participants Est. completion 2028-06-26 1 site Stand-aloneOther conditions: Pancreatic Ductal Adenocarcinoma (PDAC), Unresectable Locally Advanced or Metastatic DiseaseView official trial listing → -
Recruiting NCT NCT07480941
Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma
Not yet reported Beijing Biotech 36 participants Est. completion 2028-03-17 1 site Stand-aloneOther conditions: Glioblastoma, High-grade Glioma, Malignant Glioma, Recurrent Glioblastoma, Recurrent High-grade GliomaView official trial listing → -
Recruiting NCT NCT07480954
Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16)
Not yet reported, Not yet reported Beijing Biotech 36 participants Est. completion 2028-05-17 1 site Stand-aloneOther conditions: Epithelial Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube Carcinoma, Recurrent or Refractory Disease After Standard TherapiesView official trial listing → -
Recruiting NCT NCT07486089
Dual-Target CAR-NK Cells for Advanced Breast Cancer (HER2+ and TNBC)
Not yet reported, Not yet reported Beijing Biotech 60 participants Est. completion 2028-03-17 1 site Stand-aloneOther conditions: Breast Cancer (Locally Advanced or Metastatic), HER2-positive Breast Cancer, Triple-Negative Breast Cancer (TNBC)View official trial listing → -
Recruiting NCT NCT07487597
Functionally Enhanced ALPP-Targeted Engineered T Cells in Advanced Solid Tumors
Not yet reported TCRCure Biopharma Ltd. 24 participants Est. completion 2029-02-28 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Recruiting NCT NCT07490041
Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases
Not yet reported The Children's Hospital of Zhejiang University School of Medicine 36 participants Est. completion 2027-12-19 1 site Stand-aloneOther conditions: Rheumatic Diseases, Pediatric Rheumatological Condition (i.e., Arthritis, SLE, Kawasaki's Disaese), Systemic Lupus Erythematosus (SLE), Connective Tissue Disease-associated Interstitial Lung DiseaseView official trial listing → -
Recruiting NCT NCT07492628
Dual-Target Nectin-4/HER2 CAR-NK Cells in Advanced Urothelial Carcinoma
Not yet reported Beijing Biotech 42 participants Est. completion 2028-05-17 1 site Stand-aloneOther conditions: Bladder Cancer, Urothelial Carcinoma, Metastatic Urothelial Carcinoma, Locally Advanced Urothelial Carcinoma, Upper Tract Urothelial CarcinomaView official trial listing → -
Recruiting NCT NCT07493538
MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases
Not yet reported Masonic Cancer Center, University of Minnesota 132 participants Est. completion 2035-03 1 site Stand-aloneOther conditions: AML, MDS, Acute Leukemia, Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT07500220
Dual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCC
Not yet reported, Not yet reported Beijing Biotech 30 participants Est. completion 2028-03-17 1 site Stand-aloneOther conditions: Advanced Hepatocellular Carcinoma (HCC), Metastatic Liver CancerView official trial listing → -
Recruiting NCT NCT07502287
Dual-Target GD2/B7-H3 CAR-NK Cells for Pediatric Relapsed or Refractory Neuroblastoma
Not yet reported, Not yet reported Beijing Biotech 36 participants Est. completion 2028-06-17 1 site Stand-aloneOther conditions: Relapsed Neuroblastoma, Refractory Neuroblastoma, High-Risk Neuroblastoma, GanglioneuroblastomaView official trial listing → -
Recruiting NCT NCT07508605
Efficacy and Safety of CD19/CD20 CAR/TRuC-T in Relapsed/Refractory B-Cell Lymphoma
Not yet reported, Not yet reported Shenzhen University General Hospital 20 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: Relapsed/Refractory B-cell LymphomaView official trial listing → -
Recruiting NCT NCT07509034
Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease
Not yet reported National Cancer Institute (NCI) 40 participants Est. completion 2031-01-30 1 site Stand-aloneOther conditions: Recurrent Small Cell Lung Cancer, Extensive-Stage Small Cell Lung Cancer, Small Cell Lung Cancer, Small Cell Lung Carcinoma, Refractory Small Cell Lung Cancer, Extrapulmonary Small Cell Carcinoma, Neuroendocrine Carcinoma, Poorly Differentiated Neuroendocrine Carcinoma, High-Grade Neuroendocrine CarcinomaView official trial listing → -
Recruiting NCT NCT07509086
IL-15-Armored CAR-T Therapy in Relapsed or Refractory Multiple Myeloma and Plasma Cell Leukemia
Not yet reported The First Hospital of Jilin University 25 participants Est. completion 2029-07-15 1 site Stand-aloneOther conditions: Relapsed/Refractory Multiple Myeloma, Plasma Cell Leukemia (PCL)View official trial listing → -
Recruiting NCT NCT07510802
Dual-Target CAR-NK Cells for Advanced Breast Cancer HER2+ TNBC
Not yet reported, Not yet reported Beijing Biotech 60 participants Est. completion 2028-04-17 1 site Stand-aloneOther conditions: Breast Cancer (Advanced/Metastatic), HER2-positive Breast Cancer, Triple-negative Breast CancerView official trial listing → -
Recruiting NCT NCT07510828
PRISM-NK: Precision-Matched Allogeneic Single- or Dual-Target CAR-NK Cells for Advanced Solid Tumors
Not yet reported, Not yet reported Beijing Biotech 60 participants Est. completion 2028-04-17 1 site Stand-aloneOther conditions: Advanced or Metastatic Solid TumorsView official trial listing → -
Recruiting NCT NCT07519187
CAR 70-BCMA CAR-T Cells for the Treatment of Relapsed or Refractory Plasma Cell Neoplasms
Not yet reported The General Hospital of Western Theater Command 20 participants Est. completion 2028-04-01 1 site Stand-aloneOther conditions: Relapsed or Refractory Plasma Cell NeoplasmsView official trial listing → -
Recruiting NCT NCT07523529
Biomarker-Guided Dual-Target CAR-T Cells for Advanced Solid Tumors
Not yet reported, Not yet reported Beijing Biotech 72 participants Est. completion 2028-03-17 1 site Stand-aloneOther conditions: Advanced Unresectable, MetastaticView official trial listing → -
Recruiting NCT NCT07523542
SELECT-SLE: Biomarker-Guided CAR-T Target Selection for Refractory Lupus
Not yet reported, Not yet reported Beijing Biotech 24 participants Est. completion 2028-10-17 1 site Stand-aloneOther conditions: REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS, Lupus NephritisView official trial listing → -
Recruiting NCT NCT07523555
Adaptive Dual-Target CAR-T Cells for Relapsed or Refractory Hematologic Malignancies
Not yet reported, Not yet reported Beijing Biotech 96 participants Est. completion 2028-02-17 1 site Stand-aloneOther conditions: Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia, Relapsed/Refractory B-cell Non-Hodgkin Lymphoma or CLL/SLL, Relapsed/Refractory Multiple Myeloma or Plasma Cell Leukemia, Relapsed/Refractory Acute Myeloid Leukemia, High-risk Myelodysplastic Neoplasm, BPDCN; Relapsed/Refractory T-cell Acute Lymphoblastic Leukemia, T-lymphoblastic Lymphoma, Peripheral T-cell LymphomaView official trial listing → -
Recruiting NCT NCT07526493
Safety and Pharmacodynamics of QH103 Cell Injection in the Treatment of Patients With Relapsed/Refractory Antibody-Mediated Neurological Autoimmune Diseases.
Not yet reported Tongji Hospital 6 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Multiple Sclerosis (MS), Neuromyelitis Optica Spectrum Disorder (NMOSD), Autoimmune Encephalitis (AE), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Myasthenia Gravis (MG), Anti-Myelin Oligodendrocyte Glycoprotein Immunoglobulin G Antibody-Associated Disease (MOGAD), Idiopathic Inflammatory Myopathies (IIM)View official trial listing → -
Recruiting NCT NCT07532824
Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS
Not yet reported, Not yet reported Institute of Hematology and Blood Transfusion, Czech Republic 16 participants Est. completion 2029-11 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)/AML, Proton Therapy, MDS and AML Prior to Allogeneic SCT, Myelodysplastic NeoplasmView official trial listing → -
Recruiting NCT NCT07544589
A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers
Not yet reported Dispatch Biotherapeutics 66 participants Est. completion 2046-04 7 sites Stand-aloneOther conditions: Colorectal Cancer, Gastric Adenocarcinoma, Esophageal Adenocarcinoma, Gastroesophageal Adenocarcinoma, Biliary Tract CarcinomaView official trial listing → -
Recruiting NCT NCT07551336
Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade Glioma
Not yet reported Beijing Biotech 36 participants Est. completion 2028-04-17 1 site Stand-aloneOther conditions: Malignant Glioma, High-Grade Gliomas, Glioblastoma, Recurrent High-Grade Gliomas, Recurrent GlioblastomaView official trial listing → -
Recruiting NCT NCT07551349
Dual-target CD70/CAIX CAR-NK Cells for Advanced Clear Cell Renal Cell Carcinoma
Not yet reported, Not yet reported Beijing Biotech 36 participants Est. completion 2028-04-17 1 site Stand-aloneOther conditions: Advanced or Metastatic Clear Cell Renal Cell CarcinomaView official trial listing → -
Recruiting NCT NCT07551362
Dual-target CLDN18.2/HER2 CAR-NK Cells for Advanced Gastric/GEJ Cancer
Not yet reported, Not yet reported Beijing Biotech 36 participants Est. completion 2028-03-17 1 site Stand-aloneOther conditions: Advanced Gastric Adenocarcinoma, Advanced Gastroesophageal Junction AdenocarcinomaView official trial listing → -
Recruiting NCT NCT07558850
Exploratory Clinical Study of Anti-CD19/BCMA Universal CAR-T Cell Injection for the Treatment of Refractory Autoimmune Diseases
Not yet reported The First Affiliated Hospital with Nanjing Medical University 72 participants Est. completion 2029-01-10 1 site Stand-aloneOther conditions: Rheumatoid Arthritis, Dermatomyositis, Systemic Lupus Erythematosus, Systemic SclerosisView official trial listing → -
Recruiting NCT NCT07564232
Phase 1 Study Of LNK001 In Advanced Or Metastatic Clear Cell Renal Cell Carcinoma
Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2033-06-06 1 site Stand-aloneOther conditions: Clear Cell Renal Cell CarcinomaView official trial listing → -
Recruiting NCT NCT07565220
Thiotepa-based Conditioning Regimen With De-escalated Post-graft Cyclophosphamide for Allogeneic Stem Cell Transplantation in Hematologic Malignancies
Not yet reported Sawa Ito, MD 48 participants Est. completion 2030-11-01 1 site Stand-aloneOther conditions: Acute Lymphocytic Leukemia (ALL), Acute Myeloid Leukemia (AML), Acute Leukemia, Myelodysplastic Syndrome(MDS), Myeloproliferative Neoplasm (MPN)View official trial listing → -
Recruiting NCT NCT07566377
Cord Blood Transplantation in Children and Young Adults With Blood Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 71 participants Est. completion 2030-04-28 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, Non-hodgkin Lymphoma, Hodgkin Lymphoma, Leukemia, Lymphoma, Graft-versus-host DiseaseView official trial listing → -
Recruiting NCT NCT07570563
Clinical Study of the Safety and Efficacy of Allogeneic TCR-enhanced Vδ2 T Cell in Patients With Malignant Tumors.
Not yet reported, Not yet reported Chinese PLA General Hospital 24 participants Est. completion 2031-12-31 1 site Stand-aloneOther conditions: Hematologic Malignancy, Solid TumorView official trial listing → -
Recruiting NCT NCT07572136
Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Not yet reported National Cancer Institute (NCI) 57 participants Est. completion 2032-06-30 1 site Stand-aloneOther conditions: B-All, Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT07582172
Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome
Not yet reported City of Hope Medical Center 35 participants Est. completion 2029-04-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia With Complex Karyotype, Myelodysplastic Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Chronic Myelomonocytic Leukemia, Recurrent Myelodysplastic Syndrome, Recurrent Secondary Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic Chronic Myelomonocytic Leukemia, Refractory Myelodysplastic Syndrome, Refractory Secondary Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07584889
Efficacy and Safety of CD19-CAR.p40-T in Patients With Relapsed/Refractory CD19-Positive Hematologic Malignancies
Not yet reported, Not yet reported Shenzhen University General Hospital 10 participants Est. completion 2029-04-19 1 site Stand-aloneOther conditions: B Cell Lymphoma, Acute Lymphoblastic Leukemia, Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07586735
A Novel Conditioning Regimen for Haplo-HSCT in Older Patients With SAA
Peking University People's Hospital 64 participants Est. completion 2029-12-30 1 siteOther conditions: Severe Aplastic Anemia, Aplastic Anaemia, Hematopoietic Cell TransplantView official trial listing → -
Recruiting NCT NCT07587125
Safety and Efficacy of S103 Cells in Progressive/Refractory Multiple Sclerosis
Not yet reported Xijing Hospital 9 participants Est. completion 2029-11 1 site Stand-aloneOther conditions: Multiple Sclerosis (MS) Primary Progressive, Multiple Sclerosis, Multiple Sclerosis (MS) Secondary Progressive, Refractory Multiple SclerosisView official trial listing → -
Recruiting NCT NCT07588360
Haplo-Cord HSCT for AML/MDS
Not yet reported Fujian Medical University Union Hospital 82 participants Est. completion 2029-06-30 4 sites Stand-aloneOther conditions: MDS (Myelodysplastic Syndrome), AML (Acute Myeloid Leukemia)View official trial listing → -
Recruiting NCT NCT07588594
Thiotepa-Containing Conditioning Regimen for Allogeneic HSCT in Chronic Myelomonocytic Leukemia
Not yet reported Peking University People's Hospital 31 participants Est. completion 2028-05 1 site Stand-aloneOther conditions: Chronic Myelomonocytic Leukemia (CMML)View official trial listing → -
Recruiting NCT NCT07589517
Dual-Targeting CAR-NK Cells in Biomarker-Selected Advanced Colorectal Cancer
Not yet reported, Not yet reported Beijing Biotech 48 participants Est. completion 2028-03-17 1 site Stand-aloneOther conditions: Colorectal Cancer, Metastatic Colorectal Adenocarcinoma, Unresectable Colorectal CancerView official trial listing → -
Recruiting NCT NCT07589530
Phase 1/2 Study of EB-NK-301 (Allogeneic TROP2-CAR NK Cells) in Advanced TROP2-Expressing Solid Tumors
Not yet reported, Not yet reported Beijing Biotech 60 participants Est. completion 2028-03-17 1 site Stand-aloneOther conditions: Advanced Solid Tumors, Metastatic Solid Tumors, TROP2-Expressing Solid TumorsView official trial listing → -
Recruiting NCT NCT07589543
Dual-Target CAR-NK Cells in Recurrent or Refractory Epithelial Ovarian Cancer
Not yet reported, Not yet reported Beijing Biotech 42 participants Est. completion 2028-03-17 1 site Stand-aloneOther conditions: Epithelial Ovarian Cancer, Epithelial Ovarian Cancer, Fallopian Tube or PeritoneumView official trial listing → -
Recruiting NCT NCT07591649
Adapt NK for High Risk Myeloid Diseases as Bridge to Allo HSCT
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 18 participants Est. completion 2035-03-01 1 site Stand-aloneOther conditions: Relapsed Adult AML, Refractory AML, Acute Myelogenous LeukemiaView official trial listing → -
Recruiting NCT NCT07593820
A Phase I Interventional Open-label, Non-randomized Dose-escalation Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity, and Preliminary Anti-tumor Activity of Autologous p95HER2.CAR-TECH2Me T Cells in Patients With Selected Advanced Cancers.
Not yet reported Vall d'Hebron Institute of Oncology 15 participants Est. completion 2041-04-01 2 sites Stand-aloneOther conditions: Metastatic Gastric Cancer, Metastatic Breast Cancer, Endometrial Cancer MetastaticView official trial listing → -
Recruiting NCT NCT07594067
TCR1188-ABC Cells in KRAS-mutated Cancers
Not yet reported University of Pennsylvania 30 participants Est. completion 2042-07 1 site Stand-aloneOther conditions: Cholangiocarcinoma, Colorectal Cancer, Non-Small Cell Lung Cancer, Pancreatic AdenocarcinomaView official trial listing → -
Recruiting NCT NCT07598955
Target-Selected CAR-NK Cells (CD30, CD5, or Mesothelin) for Relapsed/Refractory B2 Thymoma or Thymic Carcinoma
Not yet reported, Not yet reported Beijing Biotech 36 participants Est. completion 2028-04-17 1 site Stand-aloneOther conditions: B2 Thymoma, Thymic CarcinomaView official trial listing → -
Recruiting NCT NCT07613723
A Study to Test the Safety, Tolerability and Effect of ZI-MA4-1 for Patients With Locally Advanced or Metastatic Solid Malignancies
Not yet reported Zelluna Immunotherapy AS 9 participants Est. completion 2032-12 2 sites Stand-aloneOther conditions: Ovarian Cancer, Squamous Non-Small Cell Lung Cancer (NSCLC), Synovial Sarcomas, Head and Neck CancerView official trial listing → -
Recruiting NCT NCT07614061
Safety and Efficacy of CD160-Enhanced Autologous Antigen-Specific T-Cells (BTC-Ag-T) in Advanced Biliary Tract Cancer
Not yet reported Shanghai Zhongshan Hospital 18 participants Est. completion 2029-12 1 site Stand-aloneOther conditions: Biliary Tract Neoplasms, Cholangiocarcinoma, Intrahepatic, Cholangiocarcinoma, Extrahepatic, Cholangiocarcinoma, Perihilar, Gallbladder CancerView official trial listing → -
Recruiting NCT NCT07617285
Allogeneic CAR-T(CT0890B) in NKG2DL+ R/R AML
Not yet reported Peking University People's Hospital 27 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: AML, Refractory/Relapse Acute Myeloid LeukemiaView official trial listing → -
Recruiting NCT NCT07617753
Dual-Targeting CAR-NK Cells for Recurrent Ovarian Cancer (MSLN, FRα, MUC16) pt2
Not yet reported, Not yet reported Beijing Biotech 36 participants Est. completion 2028-03-17 1 site Stand-aloneOther conditions: Epithelial Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube Carcinoma, Recurrent or Refractory Disease After Standard TherapiesView official trial listing → -
Recruiting NCT NCT07617805
EGFR/HER2 Dual-Target CAR-NK Cells for Recurrent or Metastatic HNSCC
Not yet reported, Not yet reported Beijing Biotech 42 participants Est. completion 2028-05-17 1 site Stand-aloneOther conditions: Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma, Biomarker-positive EGFR/HER2- Expressing HNSCCView official trial listing → -
Recruiting NCT NCT07627698
Dual-Target CSPG4/GD2 CAR-NK Cells for Advanced Melanoma
Not yet reported, Not yet reported Beijing Biotech 36 participants Est. completion 2028-06-17 1 site Stand-aloneOther conditions: Unresectable Melanoma, Metastatic Cutaneous Melanoma, Metastatic Uveal MelanomaView official trial listing → -
Recruiting NCT NCT07627711
Dual-Target CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma
Not yet reported, Not yet reported Beijing Biotech 42 participants Est. completion 2028-03-17 1 site Stand-aloneOther conditions: Pancreatic Ductal Adenocarcinoma (PDAC), Unresectable Locally Advanced, Metastatic DiseaseView official trial listing → -
Recruiting NCT NCT07641023
Dual-Target CAR-NK Cells Targeting MSLN, EGFR, or HER2 in Advanced NSCLC
Not yet reported, Not yet reported Beijing Biotech 60 participants Est. completion 2028-06-17 1 site Stand-aloneOther conditions: Non-Small Cell Lung Cancer, Advanced/MetastaticView official trial listing → -
Recruiting NCT NCT07641036
Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract Cancer
Not yet reported, Not yet reported Beijing Biotech 30 participants Est. completion 2028-10-17 1 site Stand-aloneOther conditions: Cholangiocarcinoma, Intrahepatic Cholangiocarcinoma, Extrahepatic Cholangiocarcinoma, Gallbladder Carcinoma, Biliary Tract CancerView official trial listing → -
Recruiting NCT NCT07641049
Dual-target PSMA/PSCA CAR-NK Cells in Advanced Prostate Cancer
Not yet reported Beijing Biotech 36 participants Est. completion 2028-06-17 1 site Stand-aloneOther conditions: Metastatic Castration-resistant Prostate Cancer, Advanced Prostate Adenocarcinoma, PSCA-positive Prostate Cancer, PSMA-Positive Progressive Metastatic Castration-Resistant Prostate CancerView official trial listing → -
Recruiting NCT NCT07668557
Anti-CD33-CLL1 CAR-T Cells (ICG415) for the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported iCell Gene Therapeutics 18 participants Est. completion 2029-07-04 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Recruiting NCT NCT07673367
Nemtabrutinib With CAR T Therapy in Relapsed/Refractory Mantle Cell Lymphoma
Not yet reported Vanderbilt-Ingram Cancer Center 25 participants Est. completion 2032-07-31 1 site Stand-aloneOther conditions: Recurrent Mantle Cell Lymphoma, Refractory Mantle Cell LymphomaView official trial listing → -
Recruiting NCT NCT07677306
Age-Stratified Conditioning Regimen Efficacy for MDS Haplo-HSCT
Not yet reported Peking University People's Hospital 120 participants Est. completion 2028-06-30 1 siteOther conditions: Myelodysplastic SyndromesView official trial listing → -
Recruiting NCT NCT07681388
CD19 CAR-T Therapy for Refractory Pemphigus Vulgaris
Not yet reported Jinbo Chen 3 participants Est. completion 2028-12-30 1 site Stand-aloneOther conditions: Pemphigus VulgarisView official trial listing → -
Recruiting NCT NCT07748533
HY001N for Patients With Autoimmune Hemolytic Anemia After Failure ≥3 Lines of Therapy.
Not yet reported Juventas Cell Therapy Ltd. 9 participants Est. completion 2028-10-01 1 site Stand-aloneOther conditions: Autoimmune Hemolytic Anemia (AIHA)View official trial listing → -
Recruiting NCT NCT07764978
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
Not yet reported AstraZeneca 750 participants Est. completion 2034-05-12 124 sites Stand-aloneOther conditions: Newly Diagnosed Multiple MyelomaView official trial listing → -
Recruiting NCT NCT07770802
Clinical Study of HS-IT101 Injection in the Treatment of Advanced Renal Cancer
Not yet reported Hangzhou Huasai Biomedicine Co., Ltd. 15 participants Est. completion 2028-08 2 sites Stand-aloneOther conditions: Clear Cell Renal Cell CarcinomaView official trial listing → -
Recruiting NCT NCT07830342
A Clinical Study of HS-IT101 Injection in Patients With Advanced Non-Small Cell Lung Cancer
Not yet reported Hangzhou Huasai Biomedicine Co., Ltd. 24 participants Est. completion 2028-10 1 site Stand-aloneOther conditions: Advanced NSCLCView official trial listing → -
Recruiting NCT NCT07838714
Dual-Targeted Umbilical Cord Blood CAR-T Cells Against CD19 and CD22 for the Treatment of Relapsed or Refractory Acute B-Cell Lymphoblastic Leukemia
Not yet reported Ruijin Hospital 18 participants Est. completion 2028-03-30 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Recruiting NCT NCT07855302
CD19 CAR-T Therapy for Refractory Childhood-Onset Systemic Lupus Erythematosus
Not yet reported Seoul National University Hospital 8 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Childhood-Onset Systemic Lupus Erythematosus, Refractory SLE, CD19 CAR-T Cell TherapyView official trial listing → -
Completed NCT NCT00001422
A Controlled Trial of Intermittent Fludarabine for Psoriatic Arthritis
Not yet reported National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 20 participants Est. completion 2000-04 1 siteOther conditions: Arthritis, Psoriatic, PsoriasisView official trial listing → -
Completed NCT NCT00001586
Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): DNA Microarray Gene Expression Analysis
Not yet reported National Cancer Institute (NCI) 105 participants Est. completion 2011-11 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00001637
Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older Adults
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 28 participants Est. completion 2016-12-28 1 siteOther conditions: Chronic Lymphocytic Leukemia, Graft vs Host Disease, Leukemia, Myelodysplastic Syndrome, Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00001676
Cyclophosphamide and Fludarabine to Treat Lupus Nephritis
Not yet reported National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 15 participants Est. completion 2002-11 1 siteOther conditions: Glomerulonephritis, Lupus Nephritis, Systemic Lupus ErythematosusView official trial listing → -
Completed NCT NCT00001677
Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthritis: Safety, Tolerance and Efficacy
Not yet reported National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 40 participants Est. completion 2000-04 1 siteOther conditions: Arthritis, Rheumatoid, SynovitisView official trial listing → -
Completed NCT NCT00001765
Stem Cell Transplant Following Low-Intensity Chemotherapy to Treat Chronic Granulomatous Disease
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 60 participants Est. completion 2005-02 1 siteOther conditions: Chronic Granulomatous DiseaseView official trial listing → -
Completed NCT NCT00001832
Lymphocyte Re-infusion During Immune Suppression to Treat Metastatic Melanoma
Not yet reported National Cancer Institute (NCI) 170 participants Est. completion 2010-05 1 site Stand-aloneOther conditions: Melanoma, Neoplasm MetastasisView official trial listing → -
Completed NCT NCT00002779
Fludarabine Plus Octreotide in Treating Patients With Relapsed Low-Grade Non-Hodgkin's Lymphoma
Not yet reported Alliance for Clinical Trials in Oncology 34 participants Est. completion 2015-06 20 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00002798
Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Not yet reported National Cancer Institute (NCI) 880 participants 1 site Stand-aloneOther conditions: Childhood Acute Erythroleukemia (M6), Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Monoblastic Leukemia (M5a), Childhood Acute Monocytic Leukemia (M5b), Childhood Acute Myeloblastic Leukemia With Maturation (M2), Childhood Acute Myeloblastic Leukemia Without Maturation (M1), Childhood Acute Myelomonocytic Leukemia (M4), Childhood Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes, Refractory Anemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Excess Blasts in Transformation, Refractory Anemia With Ringed Sideroblasts, Secondary Myelodysplastic Syndromes, Untreated Childhood Acute Myeloid Leukemia and Other Myeloid MalignanciesView official trial listing → -
Completed NCT NCT00002833
Peripheral Stem Cell Transplantation Plus Filgrastim in Treating Patients With Acute or Chronic Myelogenous Leukemia
Not yet reported M.D. Anderson Cancer Center 53 participants Est. completion 2002-04 1 site Stand-aloneOther conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00002838
Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory Chronic Lymphocytic Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 13 participants Est. completion 2002-07 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00003145
Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Peripheral Blood Stem Cell Transplant Followed by Donor Lymphocyte Infusion in Treating Older Patients With Chronic Myeloid Leukemia
Not yet reported Fred Hutchinson Cancer Center 18 participants 8 sites Stand-aloneOther conditions: Accelerated Phase of Disease, Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Phase of Disease, Recurrent DiseaseView official trial listing → -
Completed NCT NCT00003204
Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With Stage III or Stage IV Low-Grade Non-Hodgkin's Lymphoma
Not yet reported National Cancer Institute (NCI) 515 participants 1 site Stand-aloneOther conditions: Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Small Lymphocytic Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT00003248
Fludarabine and Monoclonal Antibody Therapy in Treating Patients With Untreated B-cell Chronic Lymphocytic Leukemia
Not yet reported Alliance for Clinical Trials in Oncology 104 participants Est. completion 2010-06 34 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00003552
Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Metastatic Melanoma
Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) Est. completion 2002-10 1 siteOther conditions: Stage IV Melanoma, Recurrent MelanomaView official trial listing → -
Completed NCT NCT00003619
Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation or Isotretinoin in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Acute Lymphocytic Leukemia
Not yet reported, Not yet reported Drexel University College of Medicine Est. completion 2004-04 2 sitesOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Myelodysplastic Syndromes, ThrombocytopeniaView official trial listing → -
Completed NCT NCT00003635
506U78 in Treating Patients With Chronic Lymphocytic Leukemia That Has Not Responded to Fludarabine or Alkylating Agents
Not yet reported GlaxoSmithKline Est. completion 2004-03 22 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00003659
Fludarabine, Cyclophosphamide, and Rituximab in Treating Patients Who Have Chronic Lymphocytic Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 39 participants Est. completion 2009-05 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00003729
Combination Chemotherapy in Treating Children With Relapsed or Refractory Acute Lymphocytic Leukemia
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 13 participants 23 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00003764
Fludarabine With or Without Cyclophosphamide in Treating Patients With Chronic Lymphocytic Leukemia
Not yet reported Eastern Cooperative Oncology Group 280 participants 218 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00003816
Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer
Not yet reported, Not yet reported Roswell Park Cancer Institute 361 participants Est. completion 2019-07-12 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Nonmalignant Neoplasm, Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT00003829
Chemotherapy in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia
Not yet reported Alliance for Clinical Trials in Oncology 34 participants Est. completion 2008-10 17 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00003838
Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 202 participants Est. completion 2020-06-18 1 site Stand-aloneOther conditions: Myeloproliferative Disorders, Acute Myelogenous Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic LeukemiaView official trial listing → -
Withdrawn NCT NCT00004114
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Hematologic Cancer
Not yet reported Jonsson Comprehensive Cancer CenterOther conditions: Leukemia, Lymphoma, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00004135
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Metastatic Kidney Cancer
Not yet reported University of Chicago 19 participants Est. completion 2007-08 1 site Stand-aloneOther conditions: Kidney Cancer, Melanoma (Skin)View official trial listing → -
Completed NCT NCT00004145
Chemotherapy Plus Biological Therapy Followed By Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Not yet reported University of Chicago 16 participants Est. completion 2011-08 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT00004194
Fludarabine in Treating Patients With Steroid-Resistant Chronic Graft- Versus-Host Disease
Not yet reported, Not yet reported Jonsson Comprehensive Cancer CenterOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT00004218
Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia
Not yet reported Leukemia Research Fund Est. completion 2007-07 86 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00004246
Radiation Therapy Plus Fludarabine in Treating Patients With Locally Advanced Cancer of the Mouth, Pharynx, or Larynx
Not yet reported M.D. Anderson Cancer Center 16 participants Est. completion 2002-12-02 1 site Stand-aloneOther conditions: Head and Neck CancerView official trial listing → -
Completed NCT NCT00004255
Treatment of Bone Marrow to Prevent Graft-Versus-Host Disease in Patients With Acute or Chronic Leukemia Undergoing Bone Marrow Transplantation
Not yet reported, Not yet reported Chimeric Therapies Est. completion 2003-05 15 sitesOther conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00004485
Bone Marrow Transplantation in Treating Children With Sickle Cell Disease
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 50 participants 2 sitesOther conditions: Sickle Cell AnemiaView official trial listing → -
Completed NCT NCT00004857
Fludarabine Followed by Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia
Not yet reported Alliance for Clinical Trials in Oncology 86 participants Est. completion 2010-02 50 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00004862
Augmerosen Plus Fludarabine and Cytarabine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 24 participants 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Withdrawn NCT NCT00004878
Donor Lymphocytes to Prevent Graft-Versus-Host Disease in Patients With Chronic Myeloid Leukemia
Not yet reported Jonsson Comprehensive Cancer CenterOther conditions: Graft Versus Host Disease, LeukemiaView official trial listing → -
Completed NCT NCT00005580
Bryostatin + Fludarabine in Treating Patients With Chronic Lymphocytic Leukemia or Relapsed Indolent Non-Hodgkin's Lymphoma
Not yet reported Virginia Commonwealth University 54 participants Est. completion 2006-08 3 sitesOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00005593
Fludarabine, Carboplatin, and Topotecan in Treating Patients With Relapsed/Refractory Acute Leukemia or Advanced Myelodysplastic Syndrome
Not yet reported Case Comprehensive Cancer Center 31 participants Est. completion 2003-03 1 siteOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00005785
Stem Cell (Modified Bone Marrow) Transplantation in HIV-Infected Patients With Blood Cancer
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 30 participants Est. completion 2001-11 1 siteOther conditions: Hematologic Neoplasm, HIV InfectionView official trial listing → -
Completed NCT NCT00005799
Fludarabine Phosphate, Low-Dose Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer
Not yet reported Fred Hutchinson Cancer Center 55 participants 7 sites Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), B-cell Chronic Lymphocytic Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Childhood Renal Cell Carcinoma, Chronic Phase Chronic Myelogenous Leukemia, Clear Cell Renal Cell Carcinoma, de Novo Myelodysplastic Syndromes, Nodal Marginal Zone B-cell Lymphoma, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Splenic Marginal Zone Lymphoma, Stage III Renal Cell Cancer, Stage IV Renal Cell Cancer, T-cell Large Granular Lymphocyte Leukemia, Type 1 Papillary Renal Cell Carcinoma, Type 2 Papillary Renal Cell Carcinoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00005802
Chemotherapy Followed by Donor White Blood Cells Plus Interleukin-2 in Treating Patients With Acute Myeloid or Lymphocytic Leukemia
Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2005-03 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00005803
Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 76 participants Est. completion 2018-10 5 sites Stand-aloneOther conditions: Prolymphocytic Leukemia, Recurrent Adult Hodgkin Lymphoma, Recurrent Childhood Hodgkin Lymphoma, Recurrent Childhood Non-Hodgkin Lymphoma, Recurrent Chronic Lymphocytic Leukemia, Recurrent Non-Hodgkin Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Refractory Small Lymphocytic Lymphoma, T-Cell Chronic Lymphocytic Leukemia, T-Cell Prolymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00005851
Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Stage IV Kidney Cancer
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 11 participants Est. completion 2018-09-27 6 sites Stand-aloneOther conditions: Recurrent Renal Cell Cancer, Stage IV Renal Cell CancerView official trial listing → -
Completed NCT NCT00005863
Combination Chemotherapy With or Without Filgrastim and/or Tretinoin in Treating Patients With Acute Myeloid Leukemia
Not yet reported Medical Research Council Est. completion 2004-12 1 siteOther conditions: Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00005898
Phase I/II Study of Total Body Irradiation, Cyclophosphamide, and Fludarabine Followed by Alternate Donor Hematopoietic Cell Transplantation in Patients With Fanconi's Anemia
Not yet reported, Not yet reported University of Minnesota 30 participants 1 siteOther conditions: Fanconi's AnemiaView official trial listing → -
Completed NCT NCT00005941
Peripheral Stem Cell Transplant, White Blood Cell Infusions, Chemotherapy, and Radiation Therapy in Treating Patients With Recurrent Metastatic Cervical or Vaginal Cancer
Not yet reported Fred Hutchinson Cancer Center Est. completion 2005-06 1 siteOther conditions: Cervical Cancer, Vaginal CancerView official trial listing → -
Completed NCT NCT00006042
Cyclophosphamide Plus Bone Marrow Transplantation in Treating Patients With Hematologic Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 1 siteOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Withdrawn NCT NCT00006090
Arsenic Trioxide in Treating Patients With Refractory or Relapsed Chronic Lymphocytic Leukemia
Not yet reported M.D. Anderson Cancer Center Est. completion 2001-10Other conditions: LeukemiaView official trial listing → -
Status unknown NCT NCT00006100
Allogeneic Epstein Barr Virus-Specific Cytotoxic T-Lymphocytes in Treating Patients With Progressive, Relapsed, or Refractory Hodgkin's Lymphoma
Not yet reported Milton S. Hershey Medical Center 1 siteOther conditions: LymphomaView official trial listing → -
Withdrawn NCT NCT00006126
Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Small Cell Lung, Breast, Testicular, or Kidney Cancer That is Metastatic or That Cannot Be Treated With Surgery
Not yet reported Northwestern University Est. completion 2001-04Other conditions: Breast Cancer, Kidney Cancer, Lung Cancer, Melanoma (Skin), Testicular Germ Cell TumorView official trial listing → -
Completed NCT NCT00006184
Chemotherapy, Stem Cell Transplantation and Donor and Patient Vaccination for Treatment of Multiple Myeloma
Not yet reported National Cancer Institute (NCI) 20 participants Est. completion 2008-01-12 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00006233
Combination Chemotherapy, Total-Body Irradiation, Peripheral Stem Cell Transplantation, and Lymphocyte Infusion in Treating Patients With Stage IV Melanoma
Not yet reported Fred Hutchinson Cancer Center Est. completion 2003-12 1 siteOther conditions: Melanoma (Skin)View official trial listing → -
Status unknown NCT NCT00006250
Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III or Stage IV Non-Hodgkin's Lymphoma
Not yet reported Lymphoma Trials Office 500 participants 59 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00006251
Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 21 participants 2 sites Stand-aloneObstructive sleep apnea Other conditions: Acute Undifferentiated Leukemia, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma, Childhood Grade III Lymphomatoid Granulomatosis, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Myelomonocytic Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, de Novo Myelodysplastic Syndromes, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Juvenile Myelomonocytic Leukemia, Mast Cell Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Myeloid/NK-cell Acute Leukemia, Nodal Marginal Zone B-cell Lymphoma, Noncutaneous Extranodal Lymphoma, Peripheral T-cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Primary Systemic Amyloidosis, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Renal Cell Cancer, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Stage II Multiple Myeloma, Stage III Multiple Myeloma, T-cell Large Granular Lymphocyte Leukemia, Testicular Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00006252
Fludarabine and Cyclophosphamide Followed by Peripheral Stem Cell Transplant in Treating Patients With Leukemia or Lymphoma
Not yet reported Cancer and Leukemia Group B 47 participants Est. completion 2011-10 19 sites Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00006379
Non-Ablative Allo HSCT For Hematologic Malignancies or SAA
Not yet reported Case Comprehensive Cancer Center 58 participants Est. completion 2011-10 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Precancerous/Nonmalignant Condition, Small Intestine CancerView official trial listing → -
Completed NCT NCT00006413
Stem Cell Transplantation to Treat Systemic Mastocytosis
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 25 participants Est. completion 2006-12-14 1 siteOther conditions: MastocytosisView official trial listing → -
Completed NCT NCT00006417
Modified Stem Cell Transplantation Procedure for Treating Chronic Granulomatous Disease
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 10 participants Est. completion 2004-11 1 siteOther conditions: Chronic Granulomatous DiseaseView official trial listing → -
Completed NCT NCT00008151
Gemtuzumab Ozogamicin, Fludarabine, and Total-body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported Fred Hutchinson Cancer Center Est. completion 2002-07 1 siteOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00008177
Radiolabeled Monoclonal Antibody Therapy, Fludarabine Phosphate, and Low-Dose Total-Body Irradiation Followed by Donor Stem Cell Transplant and Immunosuppression Therapy in Treating Older Patients With Advanced Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes
Not yet reported Fred Hutchinson Cancer Center 79 participants Est. completion 2010-12-15 1 site Stand-aloneOther conditions: Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Excess Blasts in Transformation, Refractory Anemia With Ringed Sideroblasts, Refractory Cytopenia With Multilineage Dysplasia, Secondary Myelodysplastic Syndromes, Untreated Adult Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT00008307
Combination Chemotherapy Followed by Donor Bone Marrow Transplant or Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer or Genetic Disorders
Not yet reported Herbert Irving Comprehensive Cancer Center 52 participants 1 siteOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00009984
Thalidomide With or Without Fludarabine in Treating Patients With Hematologic Cancer
Not yet reported National Cancer Institute (NCI) 70 participants 1 site Stand-aloneOther conditions: Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00010361
Study of Total Body Irradiation and Fludarabine Followed By Allogeneic Peripheral Blood Stem Cell or Bone Marrow Transplantation in Combination With Cyclosporine and Mycophenolate Mofetil in Patients With Inherited Disorders
Not yet reported Fred Hutchinson Cancer Center 20 participants 1 siteOther conditions: Metabolism, Inborn Errors, Granulomatous Disease, ChronicView official trial listing → -
Completed NCT NCT00014235
Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies
Not yet reported Fred Hutchinson Cancer Center 160 participants 11 sites Stand-aloneObstructive sleep apnea Other conditions: Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Blastic Plasmacytoid Dendritic Cell Neoplasm, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Myelomonocytic Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, de Novo Myelodysplastic Syndromes, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Juvenile Myelomonocytic Leukemia, Mast Cell Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Noncutaneous Extranodal Lymphoma, Peripheral T-cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Primary Systemic Amyloidosis, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Stage II Multiple Myeloma, Stage III Multiple Myeloma, T-cell Large Granular Lymphocyte Leukemia, Testicular Lymphoma, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid Leukemia, Untreated Childhood Acute Lymphoblastic Leukemia, Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00014508
Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma
Not yet reported Eastern Cooperative Oncology Group Est. completion 2011-05-27 12 sitesOther conditions: Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Status unknown NCT NCT00017108
Chlorambucil in Treating Patients With Advanced Chronic Lymphocytic Leukemia
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 13 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00019838
UCN-01 and Fludarabine in Treating Patients With Recurrent or Refractory Lymphoma or Leukemia
Not yet reported National Cancer Institute (NCI) 2 sitesOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00020176
Allogeneic Peripheral Stem Cell Transplantation in Treating Patients With Stage IV Breast Cancer
Not yet reported National Cancer Institute (NCI) Est. completion 2007-08 2 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00020800
Rituximab Plus Fludarabine in Treating Patients With Waldenstrom's Macroglobulinemia
Not yet reported Jonsson Comprehensive Cancer Center 7 participants 18 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00021151
Compassionate Use of Campath-1H in Treating Patients With Refractory Prolymphocytic Leukemia or Chronic Lymphocytic Leukemia
Not yet reported Case Comprehensive Cancer Center 2 participants Est. completion 2002-05 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00024440
Fludarabine and Cyclophosphamide With or Without Oblimersen in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
Not yet reported Genta Incorporated Est. completion 2007-02 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00025038
Combination Chemotherapy Followed By Donor Bone Marrow or Umbilical Cord Blood Transplant in Treating Children With Newly Diagnosed Juvenile Myelomonocytic Leukemia
Not yet reported National Cancer Institute (NCI) 100 participants 1 site Stand-aloneOther conditions: Juvenile Myelomonocytic LeukemiaView official trial listing → -
Withdrawn NCT NCT00025519
Peripheral Stem Cell Transplantation in Treating Patients With Metastatic or Recurrent Kidney Cancer
Not yet reported Fox Chase Cancer Center Est. completion 2006-10Other conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00025662
Selective T-Cell Depletion to Reduce GVHD (Patients) Receiving Stem Cell Tx to Treat Leukemia, Lymphoma or MDS
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 23 participants Est. completion 2008-02 1 siteOther conditions: Graft vs Host Disease, Myelodysplastic Syndromes, Leukemia, Leukemia, Myeloid, Leukemia, Myelomonocytic, Chronic, Leukemia, Lymphocytic, Lymphoma, Lymphoma, Mantle-cell, Lymphoma, Non-Hodgkin, Hodgkin DiseaseView official trial listing → -
Completed NCT NCT00027547
Combination Chemotherapy and Total-Body Irradiation Followed by Peripheral Stem Cell or Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2004-07 3 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00027560
Melphalan, Fludarabine, and Alemtuzumab Followed by Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 51 participants Est. completion 2009-04 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00027573
Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Metastatic or Unresectable Kidney Cancer
Not yet reported Alliance for Clinical Trials in Oncology 36 participants Est. completion 2006-06 6 sites Stand-aloneOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00027820
Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 106 participants Est. completion 2004-09-05 10 sites Stand-aloneOther conditions: Adult Acute Myeloid Leukemia in Remission, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Myelodysplastic Syndrome, Childhood Renal Cell Carcinoma, Chronic Myelomonocytic Leukemia, Clear Cell Renal Cell Carcinoma, de Novo Myelodysplastic Syndrome, Metastatic Renal Cell Cancer, Previously Treated Myelodysplastic Syndrome, Progression of Multiple Myeloma or Plasma Cell Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult Non-Hodgkin Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Non-Hodgkin Lymphoma, Refractory Anemia, Refractory Anemia With Ringed Sideroblasts, Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Renal Medullary Carcinoma, Type 1 Papillary Renal Cell Carcinoma, Type 2 Papillary Renal Cell Carcinoma, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid Leukemia, Untreated Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00027924
Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia or Myelodysplastic Syndrome
Not yet reported Fred Hutchinson Cancer Center Est. completion 2003-05 1 siteOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00028418
Clofarabine in Chronic Lymphocytic Leukemia
Not yet reported M.D. Anderson Cancer Center 100 participants Est. completion 2004-03 1 siteOther conditions: Hematologic Neoplasms, Lymphoproliferative Disorders, Leukemia, Leukemia, Lymphocytic, ChronicView official trial listing → -
Completed NCT NCT00028600
Peripheral Stem Cell Transplant in Treating Patients With Multiple Myeloma
Not yet reported Alliance for Clinical Trials in Oncology 60 participants Est. completion 2010-02 15 sites Stand-aloneOther conditions: Multiple Myeloma, Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00028730
Total-Body Irradiation and Chemotherapy Followed By Donor Bone Marrow Transplant in Treating Young Patients With Hematologic Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 25 participants Est. completion 2008-06 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00031005
Stem Cell Transplantation to Treat Leukocyte Adhesion Deficiency
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 10 participants Est. completion 2003-02 1 siteOther conditions: Leukocyte-Adhesion Deficiency SyndromeView official trial listing → -
Completed NCT NCT00031655
Reduced Intensity Donor Stem Cell Transplant in Treating Patients With High Risk Acute Lymphocytic Leukemia in Complete Remission
Not yet reported Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium 30 participants Est. completion 2012-11 3 sites Stand-aloneOther conditions: Adult Acute Lymphoblastic Leukemia in Remission, Childhood Acute Lymphoblastic Leukemia in Remission, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT00034528
Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 2 participants Est. completion 2003-11 1 site Stand-aloneOther conditions: Hemoglobinopathies, Anemia, Sickle Cell, Hemoglobin SC Disease, Thalassemia, Thalassemia MajorView official trial listing → -
Completed NCT NCT00036738
Fludarabine Phosphate and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Has Responded to Treatment With Imatinib Mesylate, Dasatinib, or Nilotinib
Not yet reported Fred Hutchinson Cancer Center 28 participants Est. completion 2018-05 3 sites Stand-aloneOther conditions: Adult Acute Lymphoblastic Leukemia in Remission, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Blastic Phase, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Phase of Disease, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent DiseaseView official trial listing → -
Completed NCT NCT00038831
Allo Transplantation With Mylotarg, Fludarabine and Melphalan for AML, CML and MDS
Not yet reported, Not yet reported M.D. Anderson Cancer Center 47 participants Est. completion 2006-10 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00038844
Safety and Efficacy of Campath in Nonmyeloablative Transplantation
Not yet reported M.D. Anderson Cancer Center 65 participants Est. completion 2010-09 1 site Stand-aloneOther conditions: Lymphoma, LeukemiaView official trial listing → -
Completed NCT NCT00038857
Megadose CD34 Selected Progenitor Cells for Transplantation in Patients With Advanced Hematological Malignant Diseases
Not yet reported M.D. Anderson Cancer Center 29 participants Est. completion 2009-06 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT00040417
Bone Marrow Transplant From Donor Using Less Toxic Conditioning for Patient With High Risk Hemoglobinopathies
Not yet reported Baylor College of Medicine 15 participants Est. completion 2003-11-21 2 sitesOther conditions: Sickle Cell Anemia, Hemoglobinopathy, ThalassemiaView official trial listing → -
Terminated NCT NCT00040651
Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients
Not yet reported National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 15 participants Est. completion 2007-03 1 siteOther conditions: Scleroderma, Systemic SclerosisView official trial listing → -
Completed NCT NCT00040846
Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies
Not yet reported Fred Hutchinson Cancer Center 60 participants Est. completion 2009-12 7 sites Stand-aloneObstructive sleep apnea Other conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Phase Chronic Myelogenous Leukemia, Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Contiguous Stage II Grade 1 Follicular Lymphoma, Contiguous Stage II Grade 2 Follicular Lymphoma, Contiguous Stage II Marginal Zone Lymphoma, Contiguous Stage II Small Lymphocytic Lymphoma, Hepatosplenic T-cell Lymphoma, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Noncontiguous Stage II Grade 1 Follicular Lymphoma, Noncontiguous Stage II Grade 2 Follicular Lymphoma, Noncontiguous Stage II Marginal Zone Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Peripheral T-cell Lymphoma, Previously Treated Myelodysplastic Syndromes, Progressive Hairy Cell Leukemia, Initial Treatment, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Splenic Marginal Zone Lymphoma, Stage I Adult Diffuse Small Cleaved Cell Lymphoma, Stage I Childhood Anaplastic Large Cell Lymphoma, Stage I Childhood Large Cell Lymphoma, Stage I Cutaneous T-cell Non-Hodgkin Lymphoma, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Mycosis Fungoides/Sezary Syndrome, Stage I Small Lymphocytic Lymphoma, Stage II Childhood Anaplastic Large Cell Lymphoma, Stage II Childhood Large Cell Lymphoma, Stage II Cutaneous T-cell Non-Hodgkin Lymphoma, Stage II Mycosis Fungoides/Sezary Syndrome, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Childhood Anaplastic Large Cell Lymphoma, Stage III Childhood Large Cell Lymphoma, Stage III Cutaneous T-cell Non-Hodgkin Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Mycosis Fungoides/Sezary Syndrome, Stage III Small Lymphocytic Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Childhood Anaplastic Large Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma, Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Mycosis Fungoides/Sezary Syndrome, Stage IV Small Lymphocytic Lymphoma, T-cell Large Granular Lymphocyte Leukemia, Waldenström MacroglobulinemiaView official trial listing → -
Terminated NCT NCT00041288
Study Of Two Non-Myeloablative Stem Cell Transplant Strategies For Low-Grade Lymphoma And CLL
Not yet reported University of Texas Southwestern Medical Center 10 participants Est. completion 2003-01 23 sitesOther conditions: Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT00043810
Study of Gelonin Purging of Autologous Stem Cells for Transplantation
Not yet reported, Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2005-03 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00043979
Stem Cell Transplantation in Patients With High-Risk and Recurrent Pediatric Sarcomas
Not yet reported National Cancer Institute (NCI) 60 participants Est. completion 2011-12-14 1 site Stand-aloneOther conditions: SarcomaView official trial listing → -
Completed NCT NCT00044954
Total-Body Irradiation, Fludarabine, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer
Not yet reported University of Texas Southwestern Medical Center Est. completion 2006-11 14 sitesOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00045435
Reduced Intensity Donor Peripheral Blood Stem Cell Transplant in Treating Patients With De Novo or Secondary Acute Myeloid Leukemia in Remission
Not yet reported Fred Hutchinson Cancer Center 17 participants Est. completion 2009-01 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Erythroleukemia (M6a), Adult Pure Erythroid Leukemia (M6b), Secondary Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00045513
Combination Chemotherapy in Treating Patients With Chronic Lymphocytic Leukemia or Lymphocytic Lymphoma
Not yet reported, Not yet reported University Health Network, Toronto 3 sitesOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00047060
Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary Syndrome
Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 5 participants Est. completion 2019-01-24 1 site Stand-aloneOther conditions: Mycosis Fungoides, Sezary SyndromeView official trial listing → -
Terminated NCT NCT00048399
Stem Cell Transplantation for Patients With Graft Failure Following an Allogeneic Transplant, Using Identical or Near Identical Donors and Less Toxic Conditioning With CAMPATH 1H
Not yet reported, Not yet reported Baylor College of Medicine 40 participants Est. completion 2003-10-31 2 sitesOther conditions: Graft FailureView official trial listing → -
Completed NCT NCT00048412
Stem Cell Transplant for Patients With Blood Malignancy Using Donors and Less Toxic Chemotherapy With CAMPATH 1H
Not yet reported, Not yet reported Baylor College of Medicine 40 participants Est. completion 2004-11-12 2 sitesOther conditions: Myelodysplastic Disorders, Leukemia, Multiple Myeloma, Plasma Cell Dyscrasia, Lymphoproliferative DisordersView official trial listing → -
Completed NCT NCT00048737
Safety and Efficacy of 90Y Zevalin in Nonmyeloablative Transplantation for Lymphoid Malignancies
Not yet reported, Not yet reported M.D. Anderson Cancer Center 70 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Lymphoma, LeukemiaView official trial listing → -
Terminated NCT NCT00048893
Vaccine and Chemotherapy for Previously Untreated Metastatic Breast Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 37 participants Est. completion 2011-06 2 sitesOther conditions: Breast Neoplasms, Metastases, NeoplasmView official trial listing → -
Completed NCT NCT00049075
Fludarabine in Treating Patients With Chronic Lymphocytic Leukemia
Not yet reported NCIC Clinical Trials Group 128 participants Est. completion 2009-12-21 34 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00049504
Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer
Not yet reported Fred Hutchinson Cancer Center 53 participants Est. completion 2014-02 1 site Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Cutaneous B-cell Non-Hodgkin Lymphoma, de Novo Myelodysplastic Syndromes, Hematopoietic/Lymphoid Cancer, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Peripheral T-cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic Syndromes, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Stage II Multiple Myeloma, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Hodgkin Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Adult T-cell Leukemia/Lymphoma, Stage III Childhood Hodgkin Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage III Cutaneous T-cell Non-Hodgkin Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Multiple Myeloma, Stage III Mycosis Fungoides/Sezary Syndrome, Stage III Small Lymphocytic Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Hodgkin Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Adult T-cell Leukemia/Lymphoma, Stage IV Childhood Hodgkin Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Mycosis Fungoides/Sezary Syndrome, Stage IV Small Lymphocytic Lymphoma, Testicular Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00051311
Modified Stem Cell Transplant Procedure to Treat Patients With Blood and Immune System Cancers
Not yet reported National Cancer Institute (NCI) 62 participants Est. completion 2014-09-25 1 site Stand-aloneOther conditions: Hematologic NeoplasmsView official trial listing → -
Terminated NCT NCT00053014
S0125, Chemotherapy, Total-Body Irradiation, and Peripheral Stem Cell Transplantation in Treating Older Patients With Acute Myeloid Leukemia
Not yet reported SWOG Cancer Research Network 5 participants Est. completion 2006-06 83 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00053092
Combination Chemotherapy With or Without Rituximab in Treating Patients With Mantle Cell Lymphoma
Not yet reported Institute of Cancer Research, United Kingdom 82 participants Est. completion 2009-02 2 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00053196
Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Cancer
Not yet reported Alliance for Clinical Trials in Oncology 82 participants Est. completion 2010-08 12 sites Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma, Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00053287
Fludarabine/Carboplatin/Topotecan w/Thalidomide for Relapsed/Refractory AML, CML and MDS
Not yet reported Case Comprehensive Cancer Center 42 participants Est. completion 2007-03 1 siteOther conditions: Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00053989
NMA Allogeneic Hematopoietic Cell Transplant in Hematologic Cancer/Disorders
Not yet reported Roswell Park Cancer Institute 41 participants Est. completion 2018-07-19 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Fanconi Anemia, Aplastic AnemiaView official trial listing → -
Completed NCT NCT00054236
Combination Chemotherapy Followed By Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Severe Aplastic Anemia
Not yet reported Case Comprehensive Cancer Center 55 participants Est. completion 2011-03 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00054353
Reduced-Intensity Conditioning Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 16 participants Est. completion 2012-10-14 2 sites Stand-aloneOther conditions: Refractory Multiple MyelomaView official trial listing → -
Completed NCT NCT00055653
Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders
Not yet reported Roswell Park Cancer Institute Est. completion 2005-09 25 sitesOther conditions: Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic-Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00056095
Allogeneic Stem Cell Transplant in Treating Patients With Metastatic Kidney Cancer
Not yet reported UNICANCER 57 participants Est. completion 2016-08-17 26 sites Stand-aloneOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00056966
Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation of Patients With Hematological Diseases
Not yet reported, Not yet reported Baylor College of Medicine 24 participants Est. completion 2006-12 2 sites Stand-aloneOther conditions: Hematologic MalignancyView official trial listing → -
Terminated NCT NCT00056979
Monoclonal Antibody Conditioning for Allogeneic Stem Cell Transplantation of Patients With Inherited Metabolic Storage Diseases
Not yet reported, Not yet reported Baylor College of Medicine 2 participants Est. completion 2003-06 2 sites Stand-aloneOther conditions: Inherited Metabolic Storage DiseasesView official trial listing → -
Completed NCT NCT00058227
Alvocidib, Fludarabine Phosphate, and Rituximab in Treating Patients With Lymphoproliferative Disorders or Mantle Cell Lymphoma
Not yet reported National Cancer Institute (NCI) 37 participants 1 site Stand-aloneObstructive sleep apnea Other conditions: B-cell Chronic Lymphocytic Leukemia, Contiguous Stage II Grade 1 Follicular Lymphoma, Contiguous Stage II Grade 2 Follicular Lymphoma, Contiguous Stage II Mantle Cell Lymphoma, Contiguous Stage II Marginal Zone Lymphoma, Contiguous Stage II Small Lymphocytic Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Grade 1 Follicular Lymphoma, Noncontiguous Stage II Grade 2 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Noncontiguous Stage II Marginal Zone Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Progressive Hairy Cell Leukemia, Initial Treatment, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Splenic Marginal Zone Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Small Lymphocytic Lymphoma, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Small Lymphocytic Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Small Lymphocytic Lymphoma, Untreated Hairy Cell Leukemia, Waldenström MacroglobulinemiaView official trial listing → -
Terminated NCT NCT00058825
Stem Cell Transplant for Hematologic Diseases
Not yet reported, Not yet reported Baylor College of Medicine 27 participants Est. completion 2014-09 2 sites Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT00060424
Fludarabine Phosphate and Total-Body Irradiation Before Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia
Not yet reported Fred Hutchinson Cancer Center 21 participants Est. completion 2010-09-22 3 sites Stand-aloneOther conditions: B-Cell Prolymphocytic Leukemia, Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, T-Cell Prolymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00060684
Dose Ranging Trial for Pixantrone in the FND-R Variant Regimen in Indolent Non-Hodgkin's Lymphoma
Not yet reported CTI BioPharma 30 participants Est. completion 2007-05 4 sitesOther conditions: Lymphoma, Low-Grade, Lymphoma, Small Lymphocytic, Lymphoma, Mixed-Cell, Follicular, Lymphoma, Small Cleaved-Cell, FollicularView official trial listing → -
Completed NCT NCT00061581
Experimental Bone Marrow Transplant Protocol
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 14 participants Est. completion 2017-06-14 1 siteOther conditions: Acute Lymphocytic Leukemia, Chronic Myeloid Leukemia, Acute Myelocytic Leukemia, Myelodysplastic Syndromes, Myeloproliferative DisordersView official trial listing → -
Completed NCT NCT00062036
Cyclophosphamide and Fludarabine Followed By Interleukin-2 Gene-Modified Tumor Infiltrating Lymphocytes in Treating Patients With Metastatic Melanoma
Not yet reported, Not yet reported National Institutes of Health Clinical Center (CC) 33 participants Est. completion 2008-09 2 sitesOther conditions: Melanoma (Skin)View official trial listing → -
Terminated NCT NCT00066417
Peripheral Stem Cell Transplant in Treating Patients With High-Risk Leukemia
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 51 participants Est. completion 2007-01 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00067002
Randomized Double Cord Blood Transplant Study
Not yet reported M.D. Anderson Cancer Center 110 participants Est. completion 2016-07 1 site Stand-aloneOther conditions: Leukemia, Lymphocytic, Acute, Leukemia, Myelocytic, Acute, Leukemia, Myeloid, Chronic, Lymphoma, Non-HodgkinView official trial listing → -
Completed NCT NCT00068315
Bortezomib and Fludarabine With or Without Rituximab in Treating Patients With Relapsed or Refractory Indolent Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
Not yet reported National Cancer Institute (NCI) 18 participants 7 sites Stand-aloneObstructive sleep apnea Other conditions: Hematopoietic/Lymphoid Cancer, Nodal Marginal Zone B-cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Splenic Marginal Zone Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00068523
Ultraviolet-B Light Therapy and Allogeneic Stem Cell Transplantation in Treating Patients With Hematologic Malignancies
Not yet reported Case Comprehensive Cancer Center 10 participants 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Terminated NCT NCT00069992
Total-Body Irradiation, Fludarabine, and Alemtuzumab Followed By Stem Cell Transplant in Treating Patients With Myeloproliferative Disorder, MS, AML, or CML
Not yet reported Baylor College of Medicine 7 participants Est. completion 2007-04 2 sites Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00070135
Fludarabine and Busulfan Followed by Allogeneic Stem Cell Transplant in Treating Older Patients With Acute Myeloid Leukemia in First Complete Remission
Not yet reported Alliance for Clinical Trials in Oncology 121 participants Est. completion 2016-06-15 21 sites Stand-aloneOther conditions: Adult Acute Myeloid Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00073879
Fludarabine, Cyclophosphamide, and Alemtuzumab in Treating Patients With Recurrent or Metastatic Renal Cell Carcinoma (Kidney Cancer) Undergoing Allogeneic Stem Cell Transplantation
Not yet reported Baylor College of Medicine Est. completion 2004-04 1 siteOther conditions: Kidney CancerView official trial listing → -
Terminated NCT NCT00074269
Allogeneic Stem Cell Transplant After ATG, High-Dose Melphalan, and Fludarabine for Patients With Breast Cancer
Not yet reported University of California, San Diego 5 participants Est. completion 2008-03 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT00074490
Donor Stem Cell Transplant With No or Low-Intensity Chemotherapy Using Sirolimus and Treated Immune Cells to Treat Blood and Lymph Cancers
Not yet reported National Cancer Institute (NCI) 442 participants Est. completion 2017-08-16 2 sites Stand-aloneOther conditions: Lymphoma, Leukemia, Myeloproliferative Disorders, Multiple Myleoma, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00076752
Lymphocyte Depletion and Stem Cell Transplantation to Treat Severe Systemic Lupus Erythematosus
Not yet reported National Cancer Institute (NCI) 9 participants Est. completion 2013-10-15 1 site Stand-aloneOther conditions: Lupus Erythematosus, SystemicView official trial listing → -
Completed NCT NCT00078065
Xcellerated T CellsTM in Patients With Multiple Myeloma
Not yet reported Xcyte Therapies 30 participants Est. completion 2004-06 9 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00078234
Genasense® (Oblimersen Sodium), Fludarabine, and Rituximab in Subjects With Chronic Lymphocytic Leukemia
Not yet reported, Not yet reported Genta Incorporated 25 participants Est. completion 2010-09 3 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00078858
Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 37 participants 10 sites Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Grade III Lymphomatoid Granulomatosis, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Childhood Renal Cell Carcinoma, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Clear Cell Renal Cell Carcinoma, Contiguous Stage II Adult Burkitt Lymphoma, Contiguous Stage II Adult Diffuse Large Cell Lymphoma, Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Contiguous Stage II Adult Lymphoblastic Lymphoma, Contiguous Stage II Grade 3 Follicular Lymphoma, Contiguous Stage II Mantle Cell Lymphoma, de Novo Myelodysplastic Syndromes, Hepatosplenic T-cell Lymphoma, Juvenile Myelomonocytic Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Burkitt Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Grade 3 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Noncutaneous Extranodal Lymphoma, Peripheral T-cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Renal Cell Cancer, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Anemia, Refractory Anemia With Ringed Sideroblasts, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Splenic Marginal Zone Lymphoma, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Immunoblastic Large Cell Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Adult T-cell Leukemia/Lymphoma, Stage I Childhood Anaplastic Large Cell Lymphoma, Stage I Childhood Large Cell Lymphoma, Stage I Childhood Lymphoblastic Lymphoma, Stage I Childhood Small Noncleaved Cell Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage II Adult T-cell Leukemia/Lymphoma, Stage II Childhood Anaplastic Large Cell Lymphoma, Stage II Childhood Large Cell Lymphoma, Stage II Childhood Lymphoblastic Lymphoma, Stage II Childhood Small Noncleaved Cell Lymphoma, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Adult T-cell Leukemia/Lymphoma, Stage III Childhood Anaplastic Large Cell Lymphoma, Stage III Childhood Large Cell Lymphoma, Stage III Childhood Lymphoblastic Lymphoma, Stage III Childhood Small Noncleaved Cell Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Adult T-cell Leukemia/Lymphoma, Stage IV Childhood Anaplastic Large Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma, Stage IV Childhood Lymphoblastic Lymphoma, Stage IV Childhood Small Noncleaved Cell Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Renal Cell Cancer, T-cell Large Granular Lymphocyte Leukemia, Type 1 Papillary Renal Cell Carcinoma, Type 2 Papillary Renal Cell Carcinoma, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid Leukemia, Untreated Childhood Acute Lymphoblastic Leukemia, Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00079144
Lymphocyte-Depleting Nonmyeloablative Preparative Chemotherapy Followed By Autologous Lymphocyte Infusion, Peptide Vaccine Plus Montanide ISA-51, and Interleukin-2 in Treating Patients With Metastatic Melanoma
Not yet reported National Cancer Institute (NCI) Est. completion 2005-08 2 sitesOther conditions: Melanoma (Skin)View official trial listing → -
Completed NCT NCT00079391
Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignancies
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 50 participants Est. completion 2011-09 1 siteOther conditions: Hematologic Malignancies, Bone Marrow Transplant RejectionView official trial listing → -
Terminated NCT NCT00079443
FR901228 Alone or Combined With Rituximab and Fludarabine in Treating Patients With Relapsed or Refractory Low-Grade B-Cell Non-Hodgkin's Lymphoma
Not yet reported National Cancer Institute (NCI) 60 participants 1 site Stand-aloneOther conditions: Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT00080925
T-Cell-Depleted Allogeneic Stem Cell Transplantation After Immunoablative Induction Chemotherapy and Reduced-Intensity Transplantation Conditioning in Treating Patients With Hematologic Malignancies
Not yet reported National Institutes of Health Clinical Center (CC) 20 participants Est. completion 2010-12 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00082940
Denileukin Diftitox in Treating Patients With Fludarabine-Refractory B-Cell Chronic Lymphocytic Leukemia
Not yet reported Wake Forest University Health Sciences Est. completion 2005-06 11 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00085423
Cyclophosphamide, Fludarabine, and High-Dose Interleukin-2 in Treating Patients With Metastatic Melanoma
Not yet reported Dartmouth-Hitchcock Medical Center 20 participants Est. completion 2010-02 1 site Stand-aloneOther conditions: Melanoma (Skin)View official trial listing → -
Completed NCT NCT00085462
Gene-Modified White Blood Cells Followed By Interleukin-2 and Vaccine Therapy in Treating Patients With Metastatic Melanoma
Not yet reported National Institutes of Health Clinical Center (CC) 61 participants Est. completion 2008-09 2 sitesOther conditions: Melanoma (Skin)View official trial listing → -
Completed NCT NCT00086580
Fludarabine (Fludara®) Plus Alemtuzumab (CAMPATH®, MabCampath®) vs Fludarabine Alone in B-Cell Chronic Lymphocytic Leukemia (B-CLL) Patients
Not yet reported Genzyme, a Sanofi Company 335 participants Est. completion 2010-06 48 sites Stand-aloneOther conditions: B-Cell Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00086775
Fludarabine Combined With Either Alemtuzumab or Rituximab in Treating Patients With Refractory or Relapsed B-Cell Chronic Lymphocytic Leukemia
Not yet reported Bayer Est. completion 2009-10 5 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00089011
Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body Irradiation With or Without Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant for Hematologic Cancer
Not yet reported Fred Hutchinson Cancer Center 150 participants Est. completion 2018-07 5 sites Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Blastic Phase Chronic Myelogenous Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Phase Chronic Myelogenous Leukemia, Contiguous Stage II Adult Burkitt Lymphoma, Contiguous Stage II Adult Diffuse Large Cell Lymphoma, Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Contiguous Stage II Adult Lymphoblastic Lymphoma, Contiguous Stage II Grade 1 Follicular Lymphoma, Contiguous Stage II Grade 2 Follicular Lymphoma, Contiguous Stage II Grade 3 Follicular Lymphoma, Contiguous Stage II Mantle Cell Lymphoma, Contiguous Stage II Marginal Zone Lymphoma, Contiguous Stage II Small Lymphocytic Lymphoma, Cutaneous B-cell Non-Hodgkin Lymphoma, de Novo Myelodysplastic Syndromes, Essential Thrombocythemia, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Burkitt Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Grade 1 Follicular Lymphoma, Noncontiguous Stage II Grade 2 Follicular Lymphoma, Noncontiguous Stage II Grade 3 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Noncontiguous Stage II Marginal Zone Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Noncutaneous Extranodal Lymphoma, Peripheral T-cell Lymphoma, Polycythemia Vera, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Primary Myelofibrosis, Prolymphocytic Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Diffuse Small Cleaved Cell Lymphoma, Stage I Adult Immunoblastic Large Cell Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Adult T-cell Leukemia/Lymphoma, Stage I Childhood Anaplastic Large Cell Lymphoma, Stage I Childhood Large Cell Lymphoma, Stage I Childhood Lymphoblastic Lymphoma, Stage I Childhood Small Noncleaved Cell Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage I Cutaneous T-cell Non-Hodgkin Lymphoma, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Multiple Myeloma, Stage I Small Lymphocytic Lymphoma, Stage IA Mycosis Fungoides/Sezary Syndrome, Stage IB Mycosis Fungoides/Sezary Syndrome, Stage II Adult T-cell Leukemia/Lymphoma, Stage II Childhood Anaplastic Large Cell Lymphoma, Stage II Childhood Large Cell Lymphoma, Stage II Childhood Lymphoblastic Lymphoma, Stage II Childhood Small Noncleaved Cell Lymphoma, Stage II Chronic Lymphocytic Leukemia, Stage II Cutaneous T-cell Non-Hodgkin Lymphoma, Stage II Multiple Myeloma, Stage IIA Mycosis Fungoides/Sezary Syndrome, Stage IIB Mycosis Fungoides/Sezary Syndrome, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Adult T-cell Leukemia/Lymphoma, Stage III Childhood Anaplastic Large Cell Lymphoma, Stage III Childhood Large Cell Lymphoma, Stage III Childhood Lymphoblastic Lymphoma, Stage III Childhood Small Noncleaved Cell Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage III Cutaneous T-cell Non-Hodgkin Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Multiple Myeloma, Stage III Small Lymphocytic Lymphoma, Stage IIIA Mycosis Fungoides/Sezary Syndrome, Stage IIIB Mycosis Fungoides/Sezary Syndrome, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Adult T-cell Leukemia/Lymphoma, Stage IV Childhood Anaplastic Large Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma, Stage IV Childhood Lymphoblastic Lymphoma, Stage IV Childhood Small Noncleaved Cell Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Small Lymphocytic Lymphoma, Stage IVA Mycosis Fungoides/Sezary Syndrome, Stage IVB Mycosis Fungoides/Sezary Syndrome, Testicular Lymphoma, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid Leukemia, Untreated Childhood Acute Lymphoblastic Leukemia, Untreated Childhood Acute Myeloid Leukemia and Other Myeloid Malignancies, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00089453
Study of KIR-Ligand Mismatched Haplo-Identical Natural Killer Cells Transfused Before Autologous Stem Cell Transplant
Not yet reported University of Arkansas 10 participants Est. completion 2010-05 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00090051
FCR Versus FC Alone in the Treatment of Chronic Lymphocytic Leukemia (CLL) in Relapsed Patients
Not yet reported Hoffmann-La Roche 552 participants Est. completion 2012-05-31 106 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00091104
Cyclophosphamide and Fludarabine Followed by Vaccine Therapy, Gene-Modified White Blood Cell Infusions, and Aldesleukin in Treating Patients With Metastatic Melanoma
Not yet reported National Institutes of Health Clinical Center (CC) 136 participants Est. completion 2010-10 2 sitesOther conditions: Melanoma (Skin)View official trial listing → -
Completed NCT NCT00091143
Fludarabine Followed by Vaccine Therapy and White Blood Cell Infusions in Treating Patients With Unresectable or Metastatic Melanoma
Not yet reported Providence Cancer Center, Earle A. Chiles Research Institute 20 participants Est. completion 2010-03 1 siteOther conditions: Melanoma (Skin)View official trial listing → -
Status unknown NCT NCT00093522
Vaccine Therapy With or Without Fludarabine in Treating Patients With Stage IV Kidney Cancer
Not yet reported St. Luke's Medical Center 28 participants 2 sitesOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00093743
Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed by Unrelated Donor Stem Cell Transplant in Treating Patients With Fanconi Anemia
Not yet reported Fred Hutchinson Cancer Center 2 participants 5 sites Stand-aloneOther conditions: Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Childhood Acute Myeloid Leukemia in Remission, Childhood Myelodysplastic Syndromes, Fanconi Anemia, Previously Treated Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00096018
Fludarabine and Thalidomide in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia
Not yet reported, Not yet reported Roswell Park Cancer Institute 43 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00096382
Cyclophosphamide, Fludarabine, and Total-Body Irradiation Followed By Cellular Adoptive Immunotherapy, Autologous Stem Cell Transplantation, and Interleukin-2 in Treating Patients With Metastatic Melanoma
Not yet reported National Institutes of Health Clinical Center (CC) 34 participants Est. completion 2009-01 2 sitesOther conditions: Melanoma (Skin)View official trial listing → -
Terminated NCT NCT00096460
Autologous or Donor Stem Cell Transplantation in Treating Patients With Recurrent Non-Hodgkin's Lymphoma (BMT CTN 0202)
Not yet reported, Not yet reported Medical College of Wisconsin 30 participants Est. completion 2009-03 30 sitesOther conditions: Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Follicular LymphomaView official trial listing → -
Completed NCT NCT00098670
Fludarabine, Rituximab, and Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia
Not yet reported National Cancer Institute (NCI) 102 participants Est. completion 2011-02 2 sites Stand-aloneOther conditions: B-cell Chronic Lymphocytic Leukemia, Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage IV Chronic Lymphocytic LeukemiaView official trial listing → -
Withdrawn NCT NCT00101140
Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia in Remission
Not yet reported Eastern Cooperative Oncology GroupOther conditions: Adult Acute Erythroid Leukemia, Adult Acute Monoblastic and Acute Monocytic Leukemia, Adult Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00103558
Lumiliximab in Combination With FCR in Subjects With Relapsed Chronic Lymphocytic Leukemia (CLL)
Not yet reported, Not yet reported Biogen 31 participants Est. completion 2010-03 5 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00104858
Fludarabine Phosphate, Radiation Therapy, and Rituximab in Treating Patients Who Are Undergoing Donor Stem Cell Transplant Followed by Rituximab for High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported Fred Hutchinson Cancer Center 66 participants Est. completion 2018-03-30 5 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage III Small Lymphocytic Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Small Lymphocytic Lymphoma, T-Cell Large Granular Lymphocyte LeukemiaView official trial listing → -
Completed NCT NCT00104975
Alemtuzumab and Combination Chemotherapy Followed By Donor Lymphocytes in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer
Not yet reported Yale University 20 participants Est. completion 2008-05 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00105001
Tacrolimus and Mycophenolate Mofetil With or Without Sirolimus in Preventing Acute Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer
Not yet reported Fred Hutchinson Cancer Center 210 participants Est. completion 2015-05-08 11 sites Stand-aloneOther conditions: Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndrome, Refractory Chronic Lymphocytic Leukemia, Refractory Plasma Cell Myeloma, Waldenstrom Macroglobulinemia, Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With t(9;11)(p22;q23); MLLT3-MLL, Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11, Adult Acute Promyelocytic Leukemia With t(15;17)(q22;q12); PML-RARA, Adult Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Lymphoma, Childhood Myelodysplastic Syndrome, Stage II Contiguous Adult Burkitt Lymphoma, Stage II Contiguous Adult Diffuse Large Cell Lymphoma, Stage II Contiguous Adult Diffuse Mixed Cell Lymphoma, Stage II Contiguous Adult Diffuse Small Cleaved Cell Lymphoma, Stage II Adult Contiguous Immunoblastic Lymphoma, Stage II Contiguous Adult Lymphoblastic Lymphoma, Stage II Grade 1 Contiguous Follicular Lymphoma, Stage II Grade 2 Contiguous Follicular Lymphoma, Stage II Grade 3 Contiguous Follicular Lymphoma, Stage II Contiguous Mantle Cell Lymphoma, Stage II Non-Contiguous Adult Burkitt Lymphoma, Stage II Non-Contiguous Adult Diffuse Large Cell Lymphoma, Stage II Non-Contiguous Adult Diffuse Mixed Cell Lymphoma, Stage II Non-Contiguous Adult Diffuse Small Cleaved Cell Lymphoma, Stage II Adult Non-Contiguous Immunoblastic Lymphoma, Stage II Non-Contiguous Adult Lymphoblastic Lymphoma, Stage II Grade 1 Non-Contiguous Follicular Lymphoma, Stage II Grade 2 Non-Contiguous Follicular Lymphoma, Stage II Grade 3 Non-Contiguous Follicular Lymphoma, Stage II Non-Contiguous Mantle Cell Lymphoma, Stage II Small Lymphocytic Lymphoma, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Burkitt Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Recurrent Childhood Hodgkin Lymphoma, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Secondary Myelodysplastic Syndrome, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Immunoblastic Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Childhood Anaplastic Large Cell Lymphoma, Stage I Childhood Large Cell Lymphoma, Stage I Childhood Lymphoblastic Lymphoma, Stage I Childhood Burkitt Lymphoma, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Small Lymphocytic Lymphoma, Stage II Childhood Anaplastic Large Cell Lymphoma, Stage II Childhood Lymphoblastic Lymphoma, Stage II Childhood Burkitt Lymphoma, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Immunoblastic Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Childhood Anaplastic Large Cell Lymphoma, Stage III Childhood Large Cell Lymphoma, Stage III Childhood Lymphoblastic Lymphoma, Stage III Childhood Burkitt Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Small Lymphocytic Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Immunoblastic Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Childhood Anaplastic Large Cell Lymphoma, Stage IV Childhood Large Cell Lymphoma, Stage IV Childhood Lymphoblastic Lymphoma, Stage IV Childhood Burkitt Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Small Lymphocytic LymphomaView official trial listing → -
Terminated NCT NCT00108108
Dose-finding Trial of HCD122 in Patients With Chronic Lymphocytic Leukemia (CLL) That is Relapsed or Non-responsive to Prior Fludaribine Therapy
Not yet reported Novartis Pharmaceuticals 26 participants Est. completion 2008-06 5 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00110058
Fludarabine and Radiation Therapy in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Phase or Accelerated Phase Chronic Myelogenous Leukemia
Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2006-07 3 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00110071
Iodine I 131 Tositumomab and Fludarabine Phosphate in Treating Older Patients Who Are Undergoing an Autologous or Syngeneic Stem Cell Transplant for Relapsed or Refractory Non-Hodgkin's Lymphoma
Not yet reported Fred Hutchinson Cancer Center 38 participants 1 site Stand-aloneObstructive sleep apnea Other conditions: Nodal Marginal Zone B-cell Lymphoma, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Splenic Marginal Zone Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00112567
Total-Body Irradiation, Thiotepa, and Fludarabine in Treating Young Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 20 participants Est. completion 2007-07 2 sitesOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00112593
Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer
Not yet reported Fred Hutchinson Cancer Center 5 participants 1 site Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Aggressive NK-cell Leukemia, AIDS-related Diffuse Large Cell Lymphoma, AIDS-related Diffuse Mixed Cell Lymphoma, AIDS-related Diffuse Small Cleaved Cell Lymphoma, AIDS-related Immunoblastic Large Cell Lymphoma, AIDS-related Lymphoblastic Lymphoma, AIDS-related Peripheral/Systemic Lymphoma, AIDS-related Primary CNS Lymphoma, AIDS-related Small Noncleaved Cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Blastic Phase Chronic Myelogenous Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Grade III Lymphomatoid Granulomatosis, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Eosinophilic Leukemia, Chronic Myelomonocytic Leukemia, Chronic Neutrophilic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Contiguous Stage II Adult Burkitt Lymphoma, Contiguous Stage II Adult Diffuse Large Cell Lymphoma, Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Contiguous Stage II Adult Lymphoblastic Lymphoma, Contiguous Stage II Grade 1 Follicular Lymphoma, Contiguous Stage II Grade 2 Follicular Lymphoma, Contiguous Stage II Grade 3 Follicular Lymphoma, Contiguous Stage II Mantle Cell Lymphoma, Contiguous Stage II Marginal Zone Lymphoma, Contiguous Stage II Small Lymphocytic Lymphoma, Cutaneous B-cell Non-Hodgkin Lymphoma, Essential Thrombocythemia, Extramedullary Plasmacytoma, Hepatosplenic T-cell Lymphoma, HIV Infection, HIV-associated Hodgkin Lymphoma, Intraocular Lymphoma, Isolated Plasmacytoma of Bone, Juvenile Myelomonocytic Leukemia, Mast Cell Leukemia, Meningeal Chronic Myelogenous Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Myeloid/NK-cell Acute Leukemia, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Burkitt Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Grade 1 Follicular Lymphoma, Noncontiguous Stage II Grade 2 Follicular Lymphoma, Noncontiguous Stage II Grade 3 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Noncontiguous Stage II Marginal Zone Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Noncutaneous Extranodal Lymphoma, Peripheral T-cell Lymphoma, Polycythemia Vera, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Primary Central Nervous System Lymphoma, Primary Myelofibrosis, Primary Systemic Amyloidosis, Progressive Hairy Cell Leukemia, Initial Treatment, Prolymphocytic Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Stage 0 Chronic Lymphocytic Leukemia, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Diffuse Small Cleaved Cell Lymphoma, Stage I Adult Hodgkin Lymphoma, Stage I Adult Immunoblastic Large Cell Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Adult T-cell Leukemia/Lymphoma, Stage I Childhood Anaplastic Large Cell Lymphoma, Stage I Childhood Hodgkin Lymphoma, Stage I Childhood Large Cell Lymphoma, Stage I Childhood Lymphoblastic Lymphoma, Stage I Childhood Small Noncleaved Cell Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage I Cutaneous T-cell Non-Hodgkin Lymphoma, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Multiple Myeloma, Stage I Small Lymphocytic Lymphoma, Stage IA Mycosis Fungoides/Sezary Syndrome, Stage IB Mycosis Fungoides/Sezary Syndrome, Stage II Adult Hodgkin Lymphoma, Stage II Adult T-cell Leukemia/Lymphoma, Stage II Childhood Anaplastic Large Cell Lymphoma, Stage II Childhood Hodgkin Lymphoma, Stage II Childhood Large Cell Lymphoma, Stage II Childhood Lymphoblastic Lymphoma, Stage II Childhood Small Noncleaved Cell Lymphoma, Stage II Chronic Lymphocytic Leukemia, Stage II Cutaneous T-cell Non-Hodgkin Lymphoma, Stage II Multiple Myeloma, Stage IIA Mycosis Fungoides/Sezary Syndrome, Stage IIB Mycosis Fungoides/Sezary Syndrome, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Hodgkin Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Adult T-cell Leukemia/Lymphoma, Stage III Childhood Anaplastic Large Cell Lymphoma, Stage III Childhood Hodgkin Lymphoma, Stage III Childhood Large Cell Lymphoma, Stage III Childhood Lymphoblastic Lymphoma, Stage III Childhood Small Noncleaved Cell Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage III Cutaneous T-cell Non-Hodgkin Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Multiple Myeloma, Stage III Small Lymphocytic Lymphoma, Stage IIIA Mycosis Fungoides/Sezary Syndrome, Stage IIIB Mycosis Fungoides/Sezary Syndrome, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Hodgkin Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Adult T-cell Leukemia/Lymphoma, Stage IV Childhood Anaplastic Large Cell Lymphoma, Stage IV Childhood Hodgkin Lymphoma, Stage IV Childhood Large Cell Lymphoma, Stage IV Childhood Lymphoblastic Lymphoma, Stage IV Childhood Small Noncleaved Cell Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Small Lymphocytic Lymphoma, Stage IVA Mycosis Fungoides/Sezary Syndrome, Stage IVB Mycosis Fungoides/Sezary Syndrome, T-cell Large Granular Lymphocyte Leukemia, Testicular Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific, Waldenström MacroglobulinemiaView official trial listing → -
Terminated NCT NCT00113646
Non-Myeloablative HLA-Mismatched Ex-Vivo T-cell Depleted Stem Cell Transplantation for Hematologic Malignancies
Not yet reported Massachusetts General Hospital 14 participants Est. completion 2007-12 1 siteOther conditions: Lymphoma, Leukemia, Multiple Myeloma, Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT00113828
Non-Myeloablative HLA-Matched Ex-Vivo T-cell Depleted Stem Cell Transplantation for Hematologic Malignancies
Not yet reported Massachusetts General Hospital 5 participants Est. completion 2007-03 1 site Stand-aloneOther conditions: Lymphoma, Leukemia, Multiple Myeloma, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00117156
Fludarabine and Rituximab for the Treatment of Marginal Zone Non-Hodgkin's Lymphoma
Not yet reported Dana-Farber Cancer Institute 26 participants Est. completion 2012-01 4 sites Stand-aloneOther conditions: Lymphoma, Non-Hodgkin, MALT LymphomaView official trial listing → -
Completed NCT NCT00117598
Study Evaluating Temsirolimus (CCI-779) In Mantle Cell Lymphoma (MCL)
Not yet reported Pfizer 169 participants Est. completion 2011-01 73 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00118352
Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Hematologic Cancer
Not yet reported Fred Hutchinson Cancer Center 12 participants Est. completion 2015-05-26 2 sites Stand-aloneObstructive sleep apnea Other conditions: Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Juvenile Myelomonocytic Leukemia, Mast Cell Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Noncutaneous Extranodal Lymphoma, Peripheral T-cell Lymphoma, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic Syndromes, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Testicular Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00119340
Fludarabine, Total-Body Irradiation, and Donor Stem Cell Transplant Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Chronic Myelogenous Leukemia
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 75 participants Est. completion 2007-11 3 sitesOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00119366
Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported Fred Hutchinson Cancer Center 18 participants Est. completion 2019-05-08 1 site Stand-aloneOther conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Childhood Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Excess Blasts in Transformation, Refractory Anemia With Ringed Sideroblasts, Refractory Cytopenia With Multilineage Dysplasia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00119392
Yttrium Y 90 Ibritumomab Tiuxetan, Fludarabine, Radiation Therapy, and Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma
Not yet reported Fred Hutchinson Cancer Center 42 participants Est. completion 2016-04-23 1 site Stand-aloneOther conditions: B-cell Chronic Lymphocytic Leukemia, Nodal Marginal Zone B-cell Lymphoma, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Splenic Marginal Zone Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00119730
Chemotherapy Followed by Zevalin for Relapsed Mantle Cell Lymphoma
Not yet reported Dana-Farber Cancer Institute 30 participants Est. completion 2013-12 2 sites Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Terminated NCT NCT00125606
Phase 3 Trial for AML Patients in CR2 Comparing 8Gy TBI /Fludarabine to Conditioning With TBI 12Gy/Cyclophosphamide
Not yet reported University Hospital Muenster 30 participants Est. completion 2011-07 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00133367
Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus
Not yet reported Massachusetts General Hospital 32 participants Est. completion 2011-11 2 sitesOther conditions: Multiple Myeloma, Non-Hodgkin's Lymphoma, Hodgkin's Disease, Myelogenous Leukemia, Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00134004
Fludarabine, Cyclophosphamide, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 210 participants Est. completion 2015-01 3 sites Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00138229
Cyclophosphamide and Fludarabine Followed By an Autologous Lymphocyte Infusion and Interleukin-2 in Treating Patients With Refractory or Recurrent Metastatic Melanoma
Not yet reported National Institutes of Health Clinical Center (CC) 6 participants Est. completion 2007-04 2 sitesOther conditions: Melanoma (Skin)View official trial listing → -
Completed NCT NCT00140569
Randomized Study for Patients With Follicular Lymphoma Needing Treatment
Not yet reported Lymphoma Study Association 400 participants Est. completion 2004-01 8 sitesOther conditions: Follicular LymphomaView official trial listing → -
Completed NCT NCT00143065
Fludarabine, Rituximab, and Alemtuzumab for B-Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported Ohio State University Comprehensive Cancer Center 8 participants Est. completion 2009-07 1 siteOther conditions: Lymphoma, Small Lymphocytic, Lymphocytic Leukemia, ChronicView official trial listing → -
Completed NCT NCT00143559
Stem Cell Transplantation as Immunotherapy for Hematologic Malignancies
Not yet reported St. Jude Children's Research Hospital 17 participants Est. completion 2009-01 1 siteOther conditions: Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndrome, Paroxysmal Nocturnal Hemoglobinuria, Hodgkin's Lymphoma, Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT00143845
Study of Low-Intensity Conditioning for Allogeneic Stem Cell Transplant
Not yet reported University of Michigan Rogel Cancer Center 54 participants Est. completion 2013-02 1 site Stand-aloneOther conditions: Multiple Myeloma, Lymphocytic Leukemia, Chronic, Lymphoma, Low-GradeView official trial listing → -
Terminated NCT NCT00145587
Stem Cell Transplantation for Children Affected With Osteopetrosis
Not yet reported St. Jude Children's Research Hospital 15 participants Est. completion 2009-02 1 siteOther conditions: OsteopetrosisView official trial listing → -
Completed NCT NCT00145613
Haploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies
Not yet reported St. Jude Children's Research Hospital 25 participants Est. completion 2009-02 1 siteOther conditions: Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Secondary AML, Myelodysplastic Syndrome (MDS), Secondary MDS, Chronic Myeloid Leukemia, Juvenile Myelomonocytic Leukemia (JMML), Paroxysmal Nocturnal Hemoglobinuria (PNH), Lymphoma, Non-Hodgkin, Hodgkin DiseaseView official trial listing → -
Completed NCT NCT00145626
HLA-Nonidentical Stem Cell and Natural Killer Cell Transplantation for Children Less the Two Years of Age With Hematologic Malignancies
Not yet reported St. Jude Children's Research Hospital 40 participants Est. completion 2016-07 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Myelodysplasia, Chronic Myeloid Leukemia, HistiocytosisView official trial listing → -
Completed NCT NCT00147901
Fludarabine, Cyclophosphamide, and Alemtuzumab in Patients With B-cell Chronic Lymphatic Leukemia (B-CLL)
Not yet reported German CLL Study Group 61 participants Est. completion 2011-11 1 site Stand-aloneOther conditions: B-cell Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT00150878
Standard vs. Reduced-Intensity Conditioning in Patients With Acute Myeloid Leukemia in First Remission
Not yet reported University Hospital Carl Gustav Carus 198 participants Est. completion 2010-12 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00153985
Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients With Hemoglobinopathies
Not yet reported Dana-Farber Cancer Institute 2 participants Est. completion 2009-07 6 sitesOther conditions: Hemoglobinopathies, Sickle Cell Disease, ThalassemiaView official trial listing → -
Status unknown NCT NCT00156858
Busulfan and Fludarabine as Conditioning for Allogeneic Stem Cell Transplantation: a Pharmacokinetic Study
Not yet reported Alberta Health services 200 participants Est. completion 2010-12 1 siteOther conditions: Hematologic MalignancyView official trial listing → -
Completed NCT NCT00160355
Haploidentical Hematopoietic Stem Cell Transplantation Patients With Wiskott-Aldrich Syndrome
Not yet reported St. Jude Children's Research Hospital 4 participants Est. completion 2009-02 1 siteOther conditions: Wiskott-Aldrich SyndromeView official trial listing → -
Terminated NCT NCT00167180
Post Transplant Donor Lymphocyte Infusion
Not yet reported Masonic Cancer Center, University of Minnesota 57 participants Est. completion 2018-12-24 1 siteOther conditions: Leukemia, Myeloid, Chronic, Lymphomas, Multiple Myeloma, Myelodysplastic Syndrome, Leukemia, Lymphocytic, Acute, Leukemia, Lymphocytic, Chronic, AMLView official trial listing → -
Terminated NCT NCT00167206
Stem Cell Transplantation for Fanconi Anemia
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 16 participants Est. completion 2008-12 1 site Stand-aloneOther conditions: Fanconi AnemiaView official trial listing → -
Completed NCT NCT00169208
Fludarabine, Mitoxantrone and Rituximab in Relapsed or Primary Failing Advanced Follicular Non-Hodgkin's Lymphoma
Not yet reported Lymphoma Study Association 50 participants Est. completion 2006-12 16 sites Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Completed NCT NCT00176852
Stem Cell Transplant for Hemoglobinopathy
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 22 participants Est. completion 2020-01 1 site Stand-aloneOther conditions: Sickle Cell Disease, Thalassemia, Severe Congenital Neutropenia, Diamond-Blackfan Anemia, Shwachman-Diamond SyndromeView official trial listing → -
Completed NCT NCT00176865
Stem Cell Transplant for Immunologic or Histiocytic Disorders
Not yet reported Masonic Cancer Center, University of Minnesota 19 participants Est. completion 2014-08 1 siteOther conditions: Hemophagocytic Lymphohistiocytosis, X-Linked Lymphoproliferative Disorders, Chediak-Higashi Syndrome, Griscelli Syndrome, Immunologic Deficiency Syndromes, Langerhans-Cell HistiocytosisView official trial listing → -
Completed NCT NCT00176878
Stem Cell Transplant for Bone Marrow Failure Syndromes
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 10 participants Est. completion 2009-03 1 site Stand-aloneOther conditions: Diamond-Blackfan Anemia, Kostmann's Neutropenia, Shwachman-Diamond SyndromeView official trial listing → -
Completed NCT NCT00179790
Reduced Intensity Transplant Using Extracorporeal Photopheresis
Not yet reported, Not yet reported Ann & Robert H Lurie Children's Hospital of Chicago 22 participants Est. completion 2015-01 1 siteOther conditions: Leukemia, CancerView official trial listing → -
Completed NCT NCT00182650
Cellular Adoptive Immunotherapy in Treating Patients With Relapsed or Refractory Follicular Non-Hodgkin's Lymphoma
Not yet reported City of Hope Medical Center 5 participants Est. completion 2008-03 1 siteOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT00183989
Combination Therapy With Fludarabine, Mitoxantrone and Rituximab in Mantle Cell Lymphoma
Not yet reported University of Southern California 30 participants Est. completion 2006-12 1 siteOther conditions: Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT00186797
Purified CD34+ Hematopoietic Stem Cell Transplantation From Alternate Donors for Patients With Severe Aplastic Anemia
Not yet reported St. Jude Children's Research Hospital 28 participants Est. completion 2007-05 1 siteOther conditions: Aplastic AnemiaView official trial listing → -
Completed NCT NCT00186966
Treatment of Children and Adolescents With Refractory or Relapsed Acute Myeloid Leukemia
Not yet reported Dutch Childhood Oncology Group 394 participants Est. completion 2010-09 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00187083
A Study of Children With Refractory or Relapsed ALL
Not yet reported St. Jude Children's Research Hospital 40 participants Est. completion 2003-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT00187096
Natural Killer (NK) Cell Transplantation for AML
Not yet reported St. Jude Children's Research Hospital 49 participants Est. completion 2013-03 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00188136
Early Allogeneic Blood Stem Cell Transplantation in High-risk Acute Myeloid Leukemia (AML)
Not yet reported University Hospital Carl Gustav Carus 32 participants Est. completion 2010-12 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00189488
Trial to Evaluate Palifermin in the Reduction of Acute Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Allogeneic Marrow/Peripheral Blood Progenitor Cell (PBPC) Transplantation
Not yet reported Swedish Orphan Biovitrum 155 participants Est. completion 2013-08 Stand-aloneOther conditions: Graft Versus Host Disease, Hematologic MalignanciesView official trial listing → -
Completed NCT NCT00193466
Rituximab and Fludarabine Followed by CAMPATH-1H in Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported SCRI Development Innovations, LLC 40 participants Est. completion 2008-04Other conditions: Non-Hodgkins LymphomaView official trial listing → -
Completed NCT NCT00198991
German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)
Not yet reported Goethe University 1883 participants Est. completion 2013-06-30 1 site Stand-aloneOther conditions: Adult Acute Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00199056
German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99)
Not yet reported Goethe University 225 participants Est. completion 2005-12 1 siteOther conditions: Adult Acute Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT00199147
Efficacy of G-CSF-Priming in Elderly AML Patients
Not yet reported Johann Wolfgang Goethe University Hospital 250 participants 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00202917
Haploidentical Transplantation With CD3/CD19 Depleted Grafts in Patients With Hematologic Malignancies
Not yet reported, Not yet reported University Hospital Tuebingen 61 participants Est. completion 2010-12 7 sitesOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT00206726
Alemtuzumab/Fludarabine for Relapsed/Refractory B-cell Chronic Lymphocytic Leukemia (B-CLL)
Not yet reported Genzyme, a Sanofi Company 60 participants Est. completion 2008-04 27 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Completed NCT NCT00208923
Allogeneic Bone Marrow Transplantation With Matched Unrelated Donors for Patients With Hematologic Malignancies
Not yet reported Emory University 55 participants Est. completion 2007-10 1 siteOther conditions: Hematologic MalignanciesView official trial listing → -
Terminated NCT NCT00208975
Phase II Study of Fludarabine and Mitoxantrone, Followed by GM-CSF(Granulocyte-macrophage Colony-stimulating Factor) and Rituximab
Not yet reported Emory University 15 participants Est. completion 2011-09 1 siteOther conditions: LymphomaView official trial listing → -
Status unknown NCT NCT00209209
Induction Chemotherapy (R-CHOP Vs. R-FC) Followed by Interferon Maintenance Versus Rituximab Maintenance in MCL
Not yet reported European Mantle Cell Lymphoma Network 570 participants Est. completion 2018-12 7 sites Stand-aloneOther conditions: Lymphoma, Mantle-CellView official trial listing → -
Status unknown NCT NCT00209833
Treatment of Adults Aged Up to 60 Years With De Novo Acute Myeloblastic Leukaemia,Secondary AML, or RAEB-T
Not yet reported, Not yet reported Hannover Medical School 200 participants Est. completion 2005-09 1 siteOther conditions: De Novo Akute Myeloid Leukemia (AML), Secondary Acute Myeloid Leukemia (AML), Refractory Anemia With Excess of Blasts in TransformationView official trial listing → -
Completed NCT NCT00220311
A Study to Confirm the Efficacy and Safety of Fludarabine Phosphate Administered in Untreated Chronic Lymphocytic Leukemia Patients With Anemia and/or Thrombocytopenia
Not yet reported Genzyme, a Sanofi Company 10 participants Est. completion 2005-09 Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Withdrawn NCT NCT00226512
To Determine the Role of Adding Campath-1H or ATG Given In-vivo in Addition to Fludarabine and Low Dose Busulfex on Outcome in Patients Treated With Reduced Intensity Conditioning
Not yet reported Hadassah Medical Organization 203 participants 1 siteOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00228852
IMM 0212: Busulfan With Fludarabine and Antithymocyte Globulin as Preparative Therapy for Hematopoietic Stem Cell Transplant for the Treatment of Severe Congenital T-Cell Immunodeficiency
Not yet reported, Not yet reported Emory University Est. completion 2006-11 1 siteOther conditions: T-Cell Immune Deficiency Diseases, Severe Combined ImmunodeficiencyView official trial listing → -
Completed NCT NCT00230282
Phase 2 Fludarabine, Cytoxan and FCCAM <Alemtuzumab> in Untreated B-Cell Chronic Lymphocytic Leukemia
Not yet reported Steven E. Coutre 25 participants Est. completion 2011-10 1 site Stand-aloneOther conditions: Leukemia, B-cell Leukemia, Chronic Leukemia, Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Withdrawn NCT NCT00242931
Flu/TBI in Treating Patients Not Responding to Previous Hormone Therapy
Not yet reported OHSU Knight Cancer Institute Est. completion 2008-03 Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00243009
Fludarabine and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Metastatic Kidney Cancer That Cannot Be Removed By Surgery
Not yet reported OHSU Knight Cancer Institute 1 participants Est. completion 2006-04 1 siteOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00244010
Partially Matched Stem Cell Transplantation for Patients With Refractory Severe Aplastic Anemia or Refractory Cytopenias
Not yet reported St. Jude Children's Research Hospital 4 participants Est. completion 2009-02 1 siteOther conditions: Anemia, Aplastic, Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Kostmann SyndromeView official trial listing → -
Completed NCT NCT00245037
Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer
Not yet reported, Not yet reported OHSU Knight Cancer Institute 147 participants Est. completion 2015-08 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous ConditionView official trial listing → -
Completed NCT NCT00253513
Treosulfan and Fludarabine in Treating Younger Patients Who Are Undergoing a Donor Stem Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome
Not yet reported, Not yet reported OHSU Knight Cancer Institute 60 participants Est. completion 2009-10 3 sitesOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00254163
Fludarabine, Cyclophosphamide, and Rituximab Versus Pentostatin, Cyclophosphamide, and Rituximab in Previously Untreated or Treated B-Cell Chronic Lymphocytic Leukemia Patients
Not yet reported US Oncology Research 184 participants Est. completion 2011-09 11 sitesOther conditions: B-Cell Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00254410
FCM-R (Fludarabine, Cyclophosphamide, Mitoxantrone, Rituximab) in Previously Untreated Patients With Chronic Lymphocytic Leukemia (CLL) < 70 Years
Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2017-09-14 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT00255684
Fludarabine, Cyclophosphamide, and Total-Body Irradiation Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients Who Are Undergoing a Donor Umbilical Cord Blood Transplant for Hematologic Cancer
Not yet reported University of Rochester 16 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00255710
Cyclophosphamide and/or Mycophenolate Mofetil With or Without Tacrolimus in Treating Patients Who Are Undergoing a Donor Bone Marrow or Peripheral Stem Cell Transplant for Hematologic Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 60 participants 1 siteOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00258427
Hematopoietic Stem Cell Transplantation in High Risk Patients With Fanconi Anemia
Not yet reported Masonic Cancer Center, University of Minnesota 14 participants Est. completion 2020-10-10 1 site Stand-aloneOther conditions: Fanconi AnemiaView official trial listing → -
Completed NCT NCT00262886
Donor Peripheral Stem Cell or Bone Marrow Transplant in Treating Patients With Relapsed or Refractory Metastatic Kidney Cancer
Not yet reported University of Rochester 35 participants 1 siteOther conditions: Kidney CancerView official trial listing → -
Completed NCT NCT00274846
Donor Peripheral Stem Cell Transplant in Treating Patients With Relapsed Acute Myeloid Leukemia
Not yet reported Masonic Cancer Center, University of Minnesota 21 participants Est. completion 2008-06 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00274976
Alemtuzumab in Treating Patients With Advanced Chronic Lymphocytic Leukemia That Did Not Respond to Previous Fludarabine
Not yet reported German CLL Study Group Est. completion 2009-08 35 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00275054
Rituximab, Fludarabine, and Cyclophosphamide or Observation Alone in Treating Patients With Stage 0, Stage I, or Stage II Chronic Lymphocytic Leukemia
Not yet reported German CLL Study Group 825 participants Est. completion 2015-06 91 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00275678
Comparison of Peripheral Blood Stem Cell Transplantation With Bone Marrow Transplantation for the Treatment of Serious Hematological Malignancies
Not yet reported Mayo Clinic 15 participants 1 siteOther conditions: Blood Stem Cell TransplantView official trial listing → -
Completed NCT NCT00276809
Combination Chemotherapy, Total-Body Irradiation, and Alemtuzumab in Treating Patients Undergoing an Autologous Stem Cell Transplant for Stage I, Stage II, Stage III, or Stage IV Chronic Lymphocytic Leukemia
Not yet reported German CLL Study Group 30 participants Est. completion 2004-09 12 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00276848
Fludarabine With or Without Cyclophosphamide in Treating Patients With Advanced Chronic Lymphocytic Leukemia
Not yet reported German CLL Study Group 375 participants Est. completion 2007-07 135 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00278213
Combination Chemotherapy Followed By Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia
Not yet reported German CLL Study Group 17 participants Est. completion 2009-12 19 sitesOther conditions: Prolymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT00278265
Methotrexate Followed by Fludarabine in Patients With T-Cell Large Granular Lymphocytic Leukemia
Not yet reported German CLL Study Group 12 participants Est. completion 2009-12 7 sites Stand-aloneOther conditions: T-Cell Large Granular Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT00278512
Hematopoietic Stem Cell Support in Vasculitis
Not yet reported Northwestern University 7 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: VasculitisView official trial listing → -
Completed NCT NCT00280241
Protocol for the Treatment of Patients With Previously Untreated Chronic Lymphocytic Leukemia
Not yet reported University of Pittsburgh 65 participants Est. completion 2013-01 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT00281879
Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer
Not yet reported OHSU Knight Cancer Institute 200 participants Est. completion 2008-03 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Unusual Cancers of ChildhoodView official trial listing → -
Completed NCT NCT00281892
Fludarabine and Darbepoetin Alfa in Treating Older Patients With Chronic Lymphocytic Leukemia
Not yet reported German CLL Study Group 97 participants Est. completion 2010-10 46 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, AnemiaView official trial listing → -
Completed NCT NCT00281918
Fludarabine and Cyclophosphamide With or Without Rituximab in Patients With Previously Untreated Chronic B-Cell Lymphocytic Leukemia
Not yet reported Hoffmann-La Roche 817 participants Est. completion 2011-10 162 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00281931
Fludarabine, Cyclophosphamide, and Rituximab in Treating Patients With Prolymphocytic Leukemia
Not yet reported German CLL Study Group 21 participants Est. completion 2006-10 1 siteOther conditions: Prolymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00281983
Fludarabine and Cyclophosphamide in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Lymphocytic Leukemia or Waldenstrom's Macroglobulinemia
Not yet reported, Not yet reported German CLL Study Group 100 participants Est. completion 2010-07 13 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00282282
Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-myeloablative Peripheral Blood Stem Cell Transplantation
Not yet reported Dana-Farber Cancer Institute 31 participants Est. completion 2009-07 1 siteOther conditions: Graft Versus Host Disease, GVHDView official trial listing → -
Terminated NCT NCT00282412
Rheumatoid Arthritis:Tolerance Induction by Mixed Chimerism
Not yet reported Northwestern University 4 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT00289549
Study of Forodesine Hydrochloride in Patients With Advanced, Fludarabine-refractory Chronic Lymphocytic Leukemia (CLL)
Not yet reported BioCryst Pharmaceuticals 8 participants Est. completion 2009-01 1 siteOther conditions: Leukemia, Lymphocytic, ChronicView official trial listing → -
Completed NCT NCT00290511
Rituximab, Fludarabine, Mitoxantrone, Dexamethasone (R-FND) Plus Zevalin for High-Risk Follicular Lymphoma
Not yet reported M.D. Anderson Cancer Center 49 participants Est. completion 2021-02-12 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00290641
Chemotherapy and Total-Body Irradiation Followed by Donor Umbilical Cord Blood Transplant, Cyclosporine, and Mycophenolate Mofetil in Treating Patients With Hematologic Cancer
Not yet reported Masonic Cancer Center, University of Minnesota 68 participants Est. completion 2006-01 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00295971
Donor Stem Cell Transplant in Treating Young Patients With Myelodysplastic Syndrome, Leukemia, Bone Marrow Failure Syndrome, or Severe Immunodeficiency Disease
Not yet reported University of California, San Francisco 21 participants Est. completion 2011-12 2 sites Stand-aloneOther conditions: Congenital Amegakaryocytic Thrombocytopenia, Leukemia, Myelodysplastic Syndromes, Severe Congenital NeutropeniaView official trial listing → -
Status unknown NCT NCT00295997
Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, or Aplastic Anemia
Not yet reported University of California, San Francisco 35 participants 2 sitesOther conditions: Chronic Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00296023
Donor Stem Cell Transplant in Treating Older or Frail Patients With Hematologic Cancer
Not yet reported University of California, San Francisco 25 participants Est. completion 2008-06 2 sites Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00301834
Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Patients With Hematologic Disorders
Not yet reported University of California, San Francisco 35 participants Est. completion 2011-09 2 sites Stand-aloneOther conditions: Congenital Amegakaryocytic Thrombocytopenia, Diamond-blackfan Anemia, Leukemia, Myelodysplastic Syndromes, Severe Congenital NeutropeniaView official trial listing → -
Terminated NCT NCT00301860
Donor Stem Cell Transplant Followed By Donor White Blood Cell Infusions in Treating Young Patients With Hematologic Cancer
Not yet reported University of California, San Francisco 8 participants Est. completion 2007-11 1 siteOther conditions: Leukemia, LymphomaView official trial listing → -
Withdrawn NCT NCT00301912
Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer
Not yet reported University of California, San Francisco 1 siteOther conditions: Anemia, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00301951
Low-Dose Fludarabine, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer
Not yet reported University of California, San Francisco 7 participants Est. completion 2009-07 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00303667
Donor Natural Killer Cells and Aldesleukin in Treating Patients w/High Risk AML Undergoing Donor Stem Cell Transplant
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 50 participants Est. completion 2011-03 1 site Stand-aloneOther conditions: Acute Myelogenous LeukemiaView official trial listing → -
Terminated NCT NCT00303719
Allogeneic Bone Marrow Transplantation Using Less Intensive Therapy
Not yet reported Masonic Cancer Center, University of Minnesota 342 participants Est. completion 2019-05-08 1 site Stand-aloneOther conditions: Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma, Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00303836
Vaccine Therapy With or Without Interleukin-2 After Chemotherapy and an Autologous White Blood Cell Infusion in Treating Patients With Metastatic Melanoma
Not yet reported National Cancer Institute (NCI) 58 participants 1 site Stand-aloneOther conditions: Recurrent Melanoma, Stage IV MelanomaView official trial listing → -
Completed NCT NCT00304018
Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer
Not yet reported University of California, San Francisco 5 participants Est. completion 2009-03 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT00304720
Tacrolimus and MMF as Post Grafting Immunosuppression After Conditioning With Flu TBI for HLA Matched Family Donor
Not yet reported Colorado Blood Cancer Institute 40 participants 1 siteOther conditions: Multiple Myeloma, Lymphoma, Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00305682
Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant
Not yet reported Masonic Cancer Center, University of Minnesota 295 participants Est. completion 2019-12-12 1 siteOther conditions: Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00305708
Busulfan, Antithymocyte Globulin, and Fludarabine Followed By a Donor Stem Cell Transplant in Treating Young Patients With Blood Disorders, Bone Marrow Disorders, Chronic Myelogenous Leukemia in First Chronic Phase, or Acute Myeloid Leukemia in First Remission
Not yet reported, Not yet reported University of California, San Francisco 40 participants Est. completion 2004-07 1 siteOther conditions: Congenital Amegakaryocytic Thrombocytopenia, Diamond-blackfan Anemia, Fanconi Anemia, Leukemia, Severe Congenital Neutropenia, ThrombocytopeniaView official trial listing → -
Completed NCT NCT00309842
Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases
Not yet reported Masonic Cancer Center, University of Minnesota 213 participants Est. completion 2019-11-22 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Myelofibrosis, MDS, Refractory Anemia, Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia, Non-Hodgkin's Lymphoma, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00309881
Combination Chemotherapy and Rituximab in Treating Patients With Chronic Lymphocytic Leukemia (CLL) That Did Not Respond to Fludarabine, CLL With Autoimmune Haemolytic Anemia (AIHA) or Richter's Transformation (RT)
Not yet reported German CLL Study Group 75 participants Est. completion 2011-03 18 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00311129
Efficacy and Safety Study of SH T 586 in Combination With Rituximab to Treat Low-Grade NHL
Not yet reported Genzyme, a Sanofi Company 41 participants Est. completion 2007-07 8 sites Stand-aloneOther conditions: Lymphoma, Low-GradeView official trial listing → -
Completed NCT NCT00313508
Dendritic Cell Vaccination During Lymphoid Reconstruction
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 18 participants Est. completion 2012-03 1 site Stand-aloneOther conditions: Intraocular Melanoma, Melanoma (Skin)View official trial listing → -
Completed NCT NCT00314106
Chemotherapy, Irradiation, Cell Infusions, and Interleukin-2 to Treat Metastatic Melanoma
Not yet reported National Cancer Institute (NCI) 26 participants Est. completion 2009-03 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT00317759
Fludarabine Followed By Adoptive Immunotherapy in Treating Patients With Stage IV Melanoma
Not yet reported Fred Hutchinson Cancer Center 12 participants Est. completion 2008-10 1 siteOther conditions: Melanoma (Skin)View official trial listing → -
Terminated NCT NCT00318110
Matched Unrelated Donor Transplant for Metastatic Renal Cell Carcinoma
Not yet reported Center for International Blood and Marrow Transplant Research 4 participants Est. completion 2009-03 5 sites Stand-aloneOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT00322101
Low-Dose or High-Dose Conditioning Followed by Peripheral Blood Stem Cell Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Myelogenous Leukemia
Not yet reported Fred Hutchinson Cancer Center 25 participants Est. completion 2014-10 8 sites Stand-aloneOther conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Childhood Acute Myeloid Leukemia in Remission, Childhood Myelodysplastic Syndromes, de Novo Myelodysplastic Syndromes, Myelodysplastic Syndrome With Isolated Del(5q), Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00324623
Cyclophosphamide and Fludarabine Followed by Cellular Adoptive Immunotherapy and Vaccine Therapy in Patients With Metastatic Melanoma
Not yet reported Prof. Serge Leyvraz 8 participants 1 site Stand-aloneOther conditions: Melanoma (Skin)View official trial listing → -
Completed NCT NCT00326417
Fludarabine-based Conditioning for Severe Aplastic Anemia (BMT CTN 0301)
Not yet reported, Not yet reported Medical College of Wisconsin 97 participants Est. completion 2016-01 22 sites Stand-aloneOther conditions: Anemia, AplasticView official trial listing → -
Status unknown NCT NCT00328237
Treatment of Hematologic Malignancies With Single-Unit or Double-Unit Cord Blood Transplantation
Not yet reported Colorado Blood Cancer Institute 20 participants 1 siteOther conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myeloid Leukemia, Non-Hodgkin Lymphoma, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00328861
Natural Killer Cells Plus IL-2 Following Chemotherapy to Treat Advanced Melanoma or Kidney Cancer
Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2009-04 1 site Stand-aloneOther conditions: Metastatic Melanoma, Metastatic Kidney CancerView official trial listing → -
Completed NCT NCT00333190
CD8+ T Cell Depletion for GVHD Prophylaxis After Peripheral Blood Stem Cell Transplantation
Not yet reported Dana-Farber Cancer Institute 30 participants Est. completion 2009-03 2 sitesOther conditions: Hematologic Malignancy, AML, ALL, CML, Multiple Myeloma, NHL, Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT00334074
Clofarabine and Ara-C for the Treatment of Relapsed AML and Untreated MDS
Not yet reported Baylor Research Institute 30 participants Est. completion 2008-02 1 siteOther conditions: Acute Myelogenous Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous LeukemiaView official trial listing → -
Completed NCT NCT00337246
Combination Chemotherapy With or Without Rituximab in Treating Patients With Previously Treated Chronic Lymphocytic Leukemia
Not yet reported Cancer Research UK 56 participants Est. completion 2011-03 16 sitesOther conditions: LeukemiaView official trial listing → -
Active, not recruiting NCT NCT00338377
Lymphodepletion Plus Adoptive Cell Transfer With or Without Dendritic Cell Immunization in Patients With Metastatic Melanoma
Not yet reported M.D. Anderson Cancer Center 1230 participants Est. completion 2030-02-28 1 site Stand-aloneOther conditions: MelanomaView official trial listing → -
Completed NCT NCT00338494
Dose Escalation Study of Clofarabine in Patients With Relapsed or Refractory Low Grade or Intermediate-Grade B-Cell Lymphoma
Not yet reported Yale University 16 participants Est. completion 2011-04 1 siteOther conditions: B-Cell LymphomaView official trial listing → -
Completed NCT NCT00342316
Reduced Intensity Conditioning Transplantation Versus Standard of Care in Acute Myeloid Leukemia
Not yet reported Vastra Gotaland Region 340 participants Est. completion 2018-07-20 25 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00343798
A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies
Not yet reported Fred Hutchinson Cancer Center 23 participants 4 sites Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Phase Chronic Myelogenous Leukemia, Contiguous Stage II Adult Burkitt Lymphoma, Contiguous Stage II Adult Diffuse Large Cell Lymphoma, Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Contiguous Stage II Adult Lymphoblastic Lymphoma, Contiguous Stage II Grade 3 Follicular Lymphoma, Contiguous Stage II Mantle Cell Lymphoma, de Novo Myelodysplastic Syndromes, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Burkitt Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Grade 3 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Previously Treated Myelodysplastic Syndromes, Prolymphocytic Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory Anemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Excess Blasts in Transformation, Refractory Chronic Lymphocytic Leukemia, Refractory Multiple Myeloma, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Splenic Marginal Zone Lymphoma, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Immunoblastic Large Cell Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Childhood Lymphoblastic Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage II Childhood Lymphoblastic Lymphoma, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Childhood Lymphoblastic Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Childhood Lymphoblastic Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT00344825
Vitalis Study - Observational Study on the Quality of Life in Patients Under Treatment for B-Chronic Lymphocytic Leukemia (B-CLL)
Genzyme, a Sanofi Company 300 participants Est. completion 2006-11 1 siteOther conditions: Leukemia, B-Cell, ChronicView official trial listing → -
Completed NCT NCT00346359
Fludarabine and Busulfan Followed by Donor Peripheral Stem Cell Transplant and Antithymocyte Globulin, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Cancer
Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2007-11 1 siteOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00349349
HuMax-CD20 in B-Cell Chronic Lymphocytic Leukemia (B-CLL) Patients Failing Fludarabine and Alemtuzumab
Not yet reported GlaxoSmithKline 223 participants Est. completion 2012-06Other conditions: Leukaemia, Lymphocytic, ChronicView official trial listing → -
Completed NCT NCT00352976
TBI Dose De-escalation for Fanconi Anemia
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 83 participants Est. completion 2020-10-09 1 site Stand-aloneOther conditions: Fanconi AnemiaView official trial listing → -
Completed NCT NCT00353860
Stem Cell Transplantation and T-Cell Add-Back to Treat Bone Marrow Malignances
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 70 participants Est. completion 2007-11-29 1 siteOther conditions: Immunosuppression, LeukemiaView official trial listing → -
Terminated NCT NCT00354172
Donor Umbilical Cord Blood Natural Killer Cells, Aldesleukin and Umbilical Cord Blood Transplant in Patients With Refractory Hematologic Cancers.
Not yet reported Masonic Cancer Center, University of Minnesota 16 participants Est. completion 2008-08 1 site Stand-aloneOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00354822
Fludarabine,Cyclophosphamide and Rituximab Followed by Zevalin for Non-Follicular Indolent Lymphomas.
Not yet reported A.O. Ospedale Papa Giovanni XXIII 25 participants Est. completion 2009-08 6 sitesOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Completed NCT NCT00357565
Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia
Not yet reported Masonic Cancer Center, University of Minnesota 34 participants Est. completion 2025-03-11 1 site Stand-aloneOther conditions: Leukemia, Myelodysplastic Syndromes, Childhood Acute Myeloid Leukemia in Remission, Recurrent Childhood Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Previously Treated Myelodysplastic Syndrome, Secondary Myelodysplastic Syndrome, Refractory Anemia With Excess Blasts in Transformation, Refractory Anemia With Excess Blasts, Refractory Anemia, De Novo Myelodysplastic Syndrome, Childhood Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT00358657
Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant and Cyclophosphamide, Mycophenolate Mofetil, Tacrolimus, and Sirolimus in Treating Patients With Primary Immunodeficiency Disorders or Noncancerous Inherited Disorders
Not yet reported Fred Hutchinson Cancer Center 14 participants Est. completion 2019-05-25 3 sites Stand-aloneOther conditions: Immunodeficiency Syndrome, Severe Aplastic Anemia, Genetic DisorderView official trial listing → -
Completed NCT NCT00361140
Busulfan Safety/Efficacy as Conditioning Prior to Hematopoietic Cell Transplantation (HCT)
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 72 participants Est. completion 2012-02 1 site Stand-aloneOther conditions: Myelodysplastic Syndromes, Myeloproliferative Disorders, Leukemia, Lymphocytic, Myeloma, LymphomaView official trial listing → -
Completed NCT NCT00365287
Combination Chemotherapy and Total-Body Irradiation Before Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer, Metastatic Breast Cancer, or Kidney Cancer
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 148 participants Est. completion 2005-12Other conditions: Breast Cancer, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00372619
Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported Children's Oncology Group 74 participants Est. completion 2012-08 79 sitesOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00373594
Therapy for Chronic Cold Agglutinin Disease
Not yet reported University of Bergen 30 participants Est. completion 2010-05 6 sitesOther conditions: Cold Agglutinin DiseaseView official trial listing → -
Completed NCT NCT00376480
Laboratory-Treated Lymphocyte Infusion After Haploidentical Donor Stem Cell Transplant
Not yet reported Dana-Farber Cancer Institute 19 participants Est. completion 2018-05-16 6 sites Stand-aloneOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00376519
Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases
Not yet reported Masonic Cancer Center, University of Minnesota 3 participants Est. completion 2008-03 1 site Stand-aloneOther conditions: Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Secondary MyelofibrosisView official trial listing → -
Terminated NCT NCT00376805
Allogeneic Natural Killer (NK) Cells in Patients With Advanced Metastatic Breast Cancer
Not yet reported Masonic Cancer Center, University of Minnesota 6 participants Est. completion 2010-01 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00378534
Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 116 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Chronic Myelogenous Leukemia, Acute Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00381004
FCR Plus Sargramostim (GM-CSF) as Frontline Therapy for Symptomatic Chronic Lymphocytic Leukemia
Not yet reported M.D. Anderson Cancer Center 60 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00381550
3-AP and Fludarabine in Treating Patients With Myeloproliferative Disorders, Chronic Myelomonocytic Leukemia, or Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia
Not yet reported National Cancer Institute (NCI) 35 participants Est. completion 2011-03 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Blastic Phase Chronic Myelogenous Leukemia, Chronic Eosinophilic Leukemia, Chronic Myelomonocytic Leukemia, Essential Thrombocythemia, Philadelphia Chromosome Negative Chronic Myelogenous Leukemia, Polycythemia Vera, Primary Myelofibrosis, Relapsing Chronic Myelogenous LeukemiaView official trial listing → -
Status unknown NCT NCT00382694
Fludarabine Added to Induction Treatment in Untreated Multiple Myeloma Patients
Not yet reported Nordic Myeloma Study Group 80 participants Est. completion 2006-12 6 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00385788
Allogeneic Blood Stem Cell Transplantation and Adoptive Immunotherapy for Hodgkin's Disease
Not yet reported M.D. Anderson Cancer Center 52 participants Est. completion 2016-08 1 site Stand-aloneOther conditions: Hodgkin's DiseaseView official trial listing → -
Completed NCT NCT00387959
Chemotherapy, Radiation Therapy, Rituximab, and Umbilical Cord Blood Transplant in Treating Patients With B-Cell Non-Hodgkin's Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 17 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Withdrawn NCT NCT00389506
Fludarabine and Cyclophosphamide Followed By LMB-2 Immunotoxin in Treating Patients With Hodgkin's Lymphoma
Not yet reported National Institutes of Health Clinical Center (CC) Est. completion 2008-05 1 siteOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT00391066
Lumiliximab With Fludarabine, Cyclophosphamide, and Rituximab (FCR) Versus FCR Alone in Subjects With Relapsed Chronic Lymphocytic Leukemia (CLL)
Not yet reported Biogen 627 participants Est. completion 2010-12 194 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT00392782
Donor Stem Cell Transplant in Treating Patients With Myeloid Cancer or Other Disease
Not yet reported Masonic Cancer Center, University of Minnesota 24 participants Est. completion 2011-05 9 sites Stand-aloneOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00393029
Phase II Study of Metastatic Cancer That Overexpresses P53 Using Lymphodepleting Conditioning Followed by Infusion of Anti-P53 TCR-Gene Engineered Lymphocytes
Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2008-11 1 site Stand-aloneOther conditions: Anti-p53 TCR-GeneView official trial listing → -
Completed NCT NCT00393107
Safety and Efficacy of Fludarabine and Cyclophosphamide + Rituximab
Not yet reported Gruppo Italiano Studio Linfomi 54 participants Est. completion 2006-08 9 sitesOther conditions: Follicular LymphomaView official trial listing → -
Withdrawn NCT NCT00396968
AMD3100 With Busulfan, Fludarabine and Thymoglobulin for Allogeneic Stem Cell Transplant for AML and MDS
Not yet reported, Not yet reported Genzyme, a Sanofi CompanyOther conditions: Acute Myelogenous Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT00397800
Rituximab, Fludarabine, Cyclophosphamide, and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Relapsed B-Cell Non-Hodgkin's Lymphoma
Not yet reported, Not yet reported Technical University of Munich 12 participants Est. completion 2013-05 12 sitesOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00397813
Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders
Not yet reported Fred Hutchinson Cancer Center 77 participants Est. completion 2018-03 3 sites Stand-aloneOther conditions: Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndrome, Essential Thrombocythemia, Myeloproliferative Neoplasm, Paroxysmal Nocturnal Hemoglobinuria, Polycythemia Vera, Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase, Primary Myelofibrosis, Refractory Anemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Ring Sideroblasts, Refractory Cytopenia With Multilineage Dysplasia, Refractory Cytopenia With Multilineage Dysplasia and Ring SideroblastsView official trial listing → -
Completed NCT NCT00402558
Alloreactive NK Cells for Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, LeukemiaView official trial listing → -
Status unknown NCT NCT00408447
Stem Cell Transplant in Sickle Cell Disease and Thalassemia
Not yet reported Columbia University 53 participants Est. completion 2025-02 1 siteOther conditions: Sickle Cell Disease, Beta ThalassemiaView official trial listing → -
Completed NCT NCT00410163
Ofatumumab With Fludarabine and Cyclophosphamide in B-CLL Patients
Not yet reported GlaxoSmithKline 61 participants Est. completion 2013-05 2 sitesOther conditions: Leukaemia, Lymphocytic, ChronicView official trial listing → -
Completed NCT NCT00412360
Single vs Double Umbilical Cord Blood Transplants in Children With High Risk Leukemia and Myelodysplasia (BMT CTN 0501)
Not yet reported Medical College of Wisconsin 224 participants Est. completion 2014-10 38 sites Stand-aloneOther conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndrome, Natural Killer Cell Lymphoblastic Leukemia/LymphomaView official trial listing → -
Terminated NCT NCT00416884
Flu,Alemtuzumab,and TBI Followed By Donor Stem Cell Chronic Phase CML
Not yet reported OHSU Knight Cancer Institute 1 participants Est. completion 2008-03 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT00416910
Combination Chemotherapy With or Without G-CSF in Treating Patients With Relapsed Chronic Lymphocytic Leukemia
Not yet reported German CLL Study Group 83 participants Est. completion 2007-09 Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00419250
A Dose Escalation Study of Lenalidomide in Relapsed or Refractory B-cell Chronic Lymphocytic Leukemia
Not yet reported Celgene 52 participants Est. completion 2010-06-01 35 sitesOther conditions: Chronic Lymphocytic Leukemia, Leukemia, B-Cell, ChronicView official trial listing → -
Completed NCT NCT00423709
Allogeneic Blood Stem Cell Transplantation
Not yet reported M.D. Anderson Cancer Center 46 participants Est. completion 2007-08 1 siteOther conditions: Hodgkin's DiseaseView official trial listing → -
No Longer Available NCT NCT00423826
Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease
Barbara Ann Karmanos Cancer Institute Est. completion 2015-01 1 siteOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Precancerous Condition, Secondary MyelofibrosisView official trial listing → -
Completed NCT NCT00425802
Chemotherapy, Total-Body Irradiation, Rituximab, and Donor Stem Cell Transplant in Treating Patients With B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 61 participants Est. completion 2016-10-28 1 siteOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00427336
Purine Analog-Based Conditioning in Patients With Severe Aplastic Anemia
Not yet reported M.D. Anderson Cancer Center 9 participants Est. completion 2009-08 1 site Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Completed NCT NCT00427557
Cellular Therapy With Cord Blood Cells
Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2010-11 1 site Stand-aloneOther conditions: Multiple Myeloma, Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00427661
A Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative Regimen
Not yet reported University of Pittsburgh 8 participants Est. completion 2014-05 1 siteOther conditions: Sickle Cell Disease, Thalassemia, HemoglobinopathiesView official trial listing → -
Terminated NCT NCT00429026
Conditioning Regimen in Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2008-03 1 site Stand-aloneOther conditions: Renal Cell CancerView official trial listing → -
Completed NCT NCT00429416
Research Study to Determine if an Experimental Agent, LLME Can Decrease the Incidence and Severity of Graft-Versus-Host-Disease (GVHD) Following Blood (Hematopoietic) Stem Cell Transplantation
Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 14 participants Est. completion 2009-05 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT00429572
Mini-Allogeneic Peripheral Blood Progenitor Cell Transplantation For Recurrent or Metastatic Breast Cancer
Not yet reported M.D. Anderson Cancer Center 19 participants Est. completion 2008-05 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT00448019
FCR and Bevacizumab in the Treatment of Relapsed Chronic Lymphocytic Leukemia (CLL)
Not yet reported M.D. Anderson Cancer Center 64 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00448201
Reduced-Intensity Busulfan and Fludarabine With or Without Antithymocyte Globulin Followed by Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Other Disease
Not yet reported UNC Lineberger Comprehensive Cancer Center 71 participants Est. completion 2012-05-23 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00448357
Allogeneic Hematopoietic Cell Transplantation for Patients With Busulfex-based Regimen
Not yet reported, Not yet reported UNC Lineberger Comprehensive Cancer Center 54 participants Est. completion 2015-11 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00450983
Donor Peripheral Stem Cell Transplant and Donor Natural Killer Cell Transplant After Total-Body Irradiation, Thiotepa, Fludarabine, and Muromonab-CD3 in Treating Patients With Leukemia or Other Blood Diseases
Not yet reported Fred Hutchinson Cancer Center 1 participants Est. completion 2010-07 2 sitesOther conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00452374
Oxaliplatin, Fludarabine, Cytarabine and Rituximab in Richter's Syndrome, Refractory CLL and PLL
Not yet reported, Not yet reported M.D. Anderson Cancer Center 48 participants Est. completion 2011-01 2 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00453388
Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation Followed by Donor Bone Marrow Transplant, Mycophenolate Mofetil, and Cyclosporine in Treating Patients With Fanconi Anemia
Not yet reported Fred Hutchinson Cancer Center 6 participants Est. completion 2013-06 5 sites Stand-aloneOther conditions: Acute Myeloid Leukemia in Remission, de Novo Myelodysplastic Syndrome, Fanconi Anemia, Previously Treated Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00455312
Stem Cell Transplant (SCT) for Dyskeratosis Congenita or SAA
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 36 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Dyskeratosis Congenita, Aplastic AnemiaView official trial listing → -
Completed NCT NCT00462332
Fludarabine and Alemtuzumab or Cyclophosphamide Followed by Peripheral Blood Stem Cell Transplant or Alemtuzumab in Treating Patients With Advanced or Progressive Chronic Lymphocytic Leukemia
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 86 participants Est. completion 2011-06 23 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00467961
Stem Cell Transplantation for Patients With Cancers of the Blood
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 61 participants Est. completion 2012-11 1 site Stand-aloneOther conditions: CML (Chronic Myelogenous Leukemia), CLL (Chronic Lymphocytic Leukemia), AML (Acute Myelogenous Leukemia), Acute Lymphocytic Leukemia, MDS (Myelodysplastic Syndrome)View official trial listing → -
Completed NCT NCT00469014
Busulfan, Fludarabine, Clofarabine With Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 72 participants Est. completion 2013-03 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome, Chronic Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00469144
IV Busulfan With Allo-BMT: Study for Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrome
Not yet reported M.D. Anderson Cancer Center 233 participants Est. completion 2014-11 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, Leukemia, Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT00472329
Fludarabine and 400 CGY Total Body Irradiation for Recipients of HLA-Matched or Mis-Matched Family or Unrelated Donor Hematopoietic Stem Cell Transplants Who Have Rejected Their First Allogeneic Stem Cell Transplant
Not yet reported Colorado Blood Cancer Institute 20 participants Est. completion 2020-12 1 siteOther conditions: Graft FailureView official trial listing → -
Terminated NCT NCT00473551
Anti-Third Party T Lymphocytes With Nonmyeloablative Stem Cell Transplantation for Indolent Lymphoid Malignancies
Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, MyelomaView official trial listing → -
Completed NCT NCT00475020
Allogeneic Stem Cell Transplantation for Myelofibrosis and Myelodysplastic Syndrome
Not yet reported M.D. Anderson Cancer Center 63 participants Est. completion 2017-10-04 1 site Stand-aloneOther conditions: MyelofibrosisView official trial listing → -
Terminated NCT NCT00478244
Allogeneic Hematopoietic Stem Cell Transplant For Epidermolysis Bullosa
Not yet reported Masonic Cancer Center, University of Minnesota 7 participants Est. completion 2011-08 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Terminated NCT NCT00480987
Oxaliplatin, Fludarabine, and Cytarabine in Acute Myeloid Leukemia (AML) or High-Risk Myelodysplastic Syndromes (MDS)
Not yet reported, Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2010-08 1 site Stand-aloneOther conditions: Myelodysplastic Syndromes, Acute Myeloid Leukemia, LeukemiaView official trial listing → -
Completed NCT NCT00487448
SMD_FLAG-IDA_98: FLAG-IDA in Induction Treatment of High Risk Myelodysplastic Syndromes or Secondary Acute Myeloblastic Leukemia
Not yet reported PETHEMA Foundation 200 participants Est. completion 2007-06 15 sitesOther conditions: Myelodysplastic Syndrome, Acute Myeloblastic LeukemiaView official trial listing → -
Completed NCT NCT00488709
Fludarabine, Cytarabine, Topotecan in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported PETHEMA Foundation 47 participants Est. completion 2007-04 16 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT00489281
Non-Myeloablative Bone Marrow Transplant for Patients With Sickle Cell Anemia and Other Blood Disorders
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 43 participants Est. completion 2018-12-29 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT00491634
Treosulfan-based Conditioning for Transplantation in AML/MDS
Not yet reported Dr. Avichai Shimoni MD 24 participants Est. completion 2014-06 1 siteOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00498316
Cord Blood Expansion on Mesenchymal Stem Cells
Not yet reported M.D. Anderson Cancer Center 98 participants Est. completion 2016-10 1 siteOther conditions: Myelodysplastic Syndrome, LeukemiaView official trial listing → -
Terminated NCT NCT00499889
Imatinib Mesylate, Busulfan, Fludarabine, and Antithymocyte Globulin for CML Patients
Not yet reported M.D. Anderson Cancer Center 42 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00505895
FM 140 vs FM100 Study in Patients With Multiple Myeloma
Not yet reported M.D. Anderson Cancer Center 52 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Terminated NCT NCT00505921
Autologous and Allogenic Transplantation With Campath-1H for T-Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00506129
Allogeneic Transplantation in Patients With Cutaneous T-Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 33 participants Est. completion 2015-06 1 site Stand-aloneOther conditions: Lymphoma, Disorder Related to Bone Marrow TransplantationView official trial listing → -
Completed NCT NCT00506857
Phase I/II Trial of Fludarabine Plus Busulfan and Allogeneic Progenitor Cell Support
Not yet reported, Not yet reported M.D. Anderson Cancer Center 82 participants Est. completion 2011-08 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT00509288
Phase II Study of Metastatic Melanoma With Lymphodepleting Conditioning and Infusion of Anti-MART-1 F5 TCR-Gene-Engineered Lymphocytes
Not yet reported National Cancer Institute (NCI) 24 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Melanoma, Skin CancerView official trial listing → -
Terminated NCT NCT00509496
Phase II Study of Metastatic Melanoma With Lymphodepleting Conditioning and Anti-gp100:154-162 TCR Gene Engineered Lymphocytes
Not yet reported National Cancer Institute (NCI) 21 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Skin Cancer, MelanomaView official trial listing → -
Terminated NCT NCT00510887
Bortezomib (Velcade) With Standard Chemotherapy for Relapsed or Refractory Follicular Lymphoma
Not yet reported Duke University 14 participants Est. completion 2013-09 1 site Stand-aloneOther conditions: Lymphoma, FollicularView official trial listing → -
Completed NCT NCT00513474
Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant
Not yet reported Massachusetts General Hospital 46 participants Est. completion 2013-02-12 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00513604
Phase II Study of Short-Term Cultured Anti-Tumor Autologous Lymphocytes After Lymphocyte-Depleting Chemotherapy in Metastatic Melanoma
Not yet reported National Cancer Institute (NCI) 158 participants Est. completion 2012-11 1 site Stand-aloneOther conditions: Melanoma, Malignant Melanoma, Melanoma, Experimental, Experimental MelanomasView official trial listing → -
Terminated NCT NCT00513747
Early or Delayed Fludarabine and Rituximab in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia
Not yet reported Alliance for Clinical Trials in Oncology 84 participants Est. completion 2016-06 387 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00516152
Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT
Not yet reported University of California, San Francisco 36 participants Est. completion 2007-11 1 siteOther conditions: Chronic Myeloid Leukemia, Acute Myelogenous Leukemia, Myelodysplasia, Acute Lymphocytic Leukemia, Severe Aplastic Anemia, Non-Hodgkin's Lymphoma, Lymphoproliferative Disease, Multiple Myeloma, Advanced Myeloproliferative DiseaseView official trial listing → -
Withdrawn NCT NCT00517218
This Study is Being Performed to Evaluate the Effect of Genasense on the Efficacy and the Safety of Rituximab/Fludarabine Combination Treatment in Previously Untreated Subjects With Chronic Lymphocyctic Leukemia(CLL)
Not yet reported Genta Incorporated Est. completion 2009-06Other conditions: Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00520130
Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune System
Not yet reported, Not yet reported National Cancer Institute (NCI) 92 participants Est. completion 2018-12-31 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, Hodgkin's Lymphoma, Non-Hodgkin's Disease, Acute Leukemia, Multiple MyelomaView official trial listing → -
Completed NCT NCT00521859
Cloretazine (VNP40101M) With Hematopoietic Cell Transplantation for Hematologic Malignancies
Not yet reported M.D. Anderson Cancer Center 5 participants Est. completion 2010-12 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Terminated NCT NCT00523809
Allogeneic Hematopoietic Stem Cell Transplantation With Bevacizumab for Advanced Solid Tumor
Not yet reported M.D. Anderson Cancer Center 5 participants Est. completion 2011-10 1 site Stand-aloneOther conditions: Breast Cancer, Ovarian CancerView official trial listing → -
Terminated NCT NCT00524667
HDAC Inhibitor Valproic Acid as an Effective Therapy for Chronic Lymphocytic Leukemia
Not yet reported CancerCare Manitoba 6 participants Est. completion 2011-07 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00525876
Non-Myeloablative Allogeneic Stem Cell Transplantation
Not yet reported M.D. Anderson Cancer Center 49 participants Est. completion 2010-09 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00526292
Chemotherapy and a Donor Natural Killer Cell Infusion in Treating Patients With Relapsed or Persistent Leukemia or Myelodysplastic Syndrome After a Donor Stem Cell Transplant
Not yet reported Memorial Sloan Kettering Cancer Center 12 participants Est. completion 2015-07 1 site Stand-aloneOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT00529880
Fludarabine and Cytarabine as Continuous Infusion Plus G-CSF Priming for Elderly Patients With Resistant AML
Not yet reported Cooperative Study Group A for Hematology 19 participants Est. completion 2007-10 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT00531310
Reduced Intensity AlloSCT in(CML) With Persistent Disease
Not yet reported Columbia University 5 participants Est. completion 2010-06 1 site Stand-aloneOther conditions: Chronic Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT00531635
Induction of Mixed Hemopoietic Chimerism in Patients Using Fludarabine, Low Dose TBI, PBSC Infusion and Post Transplant in Immunosuppression w/CSA & Mycophenolate Mofetil
Not yet reported King Faisal Specialist Hospital & Research Center 350 participants Est. completion 2012-06 1 siteOther conditions: Post Transplant in Immunosuppression w/CSA & Mycophenolate MofetilView official trial listing → -
Completed NCT NCT00533923
Nonmyeloablative Allogeneic Stem Cell Transplantation From HLA-Matched Unrelated Donor for the Treatment of Hematologic Disorders
Not yet reported Beth Israel Deaconess Medical Center 25 participants Est. completion 2007-01 1 siteOther conditions: AML, ALL, CLL, Myelodysplastic Syndrome, Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma, Multiple Myeloma, Aplastic Anemia, Myeloproliferative DisorderView official trial listing → -
Completed NCT NCT00536341
Fludarabine, Rituximab, and Lenalidomide in Minimally Treated/Untreated Patients With Chronic Lymphocytic Leukemia (CLL)
Not yet reported, Not yet reported SCRI Development Innovations, LLC 64 participants Est. completion 2016-11 6 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00536978
Natural Killer (NK) Cell Adback After Allogeneic Stem Cell Transplant With Campath-IH Plus Chemorx for Patients With Lymphoid Malignancies
Not yet reported M.D. Anderson Cancer Center 22 participants Est. completion 2010-11 1 site Stand-aloneOther conditions: Lymphoma, LeukemiaView official trial listing → -
Terminated NCT NCT00543114
Dose Escalation Study of Revlimid With Fludarabine-Rituximab for CLL/SLL
Not yet reported Dana-Farber Cancer Institute 9 participants Est. completion 2012-12 2 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00545714
A Study to Assess the Efficacy of Rituximab (MabThera) in First Line Treatment of Chronic Lymphocytic Leukemia (CLL)
Not yet reported Hoffmann-La Roche 86 participants Est. completion 2016-05-20 33 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Completed NCT NCT00547196
AlloHCT From Matched Unrelated Donors in Pts w/ Advanced Hematologic Malignancies & Disorders
Not yet reported City of Hope Medical Center 10 participants Est. completion 2024-05-28 2 sites Stand-aloneOther conditions: Leukemia, Lymphoma, Myelodysplastic SyndromesView official trial listing → -
Withdrawn NCT NCT00551239
Fludarabine and Rituximab With or Without Pixantrone in Treating Patients With Relapsed or Refractory Indolent Non-Hodgkin Lymphoma
Not yet reported CTI BioPharma 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00553098
Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by a Donor Stem Cell Transplant in Treating Patients With Immunodeficiency or Other Nonmalignant Inherited Disorders
Not yet reported Fred Hutchinson Cancer Center 29 participants 6 sites Stand-aloneOther conditions: Immunodeficiency Syndrome, Non-Cancer DiagnosisView official trial listing → -
Status unknown NCT NCT00559221
FLAG+Ida With G-CSF Priming for Patients Younger Than 60 Years With Resistant AML
Not yet reported Cooperative Study Group A for Hematology 37 participants Est. completion 2008-06 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00560053
Pethema Multiple Myeloma 2000
Not yet reported PETHEMA Foundation 500 participants Est. completion 2005-02Other conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00562640
Autologous T Cells With or Without Cyclophosphamide and Fludarabine in Treating Patients With Recurrent or Persistent Advanced Ovarian Epithelial Cancer, Primary Peritoneal Cavity Cancer, or Fallopian Tube Cancer (Fludarabine Treatment Closed as of 12/01/2009)
Not yet reported Memorial Sloan Kettering Cancer Center 12 participants Est. completion 2021-08-03 1 site Stand-aloneOther conditions: Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity CancerView official trial listing → -
Terminated NCT NCT00562965
Study Comparing Inotuzumab Ozogamicin In Combination With Rituximab Versus Defined Investigator's Choice In Follicular Non-Hodgkin's Lymphoma (NHL)
Not yet reported Pfizer 29 participants Est. completion 2011-04 39 sitesOther conditions: Lymphoma, FollicularView official trial listing → -
Completed NCT NCT00564200
MINIALO-VELCADE2005: A Study of Bortezomib (Velcade) Treated Multiple Myeloma Patients Pre and Post Allogeneic Haematopoietic Progenitor Cell Transplant With no Myeloablative Conditioning
Not yet reported PETHEMA Foundation 30 participants Est. completion 2014-10 10 sitesOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00564512
Fludarabine, Cyclophosphamide, and Rituximab or Alemtuzumab in Treating CLL2007 CLL 2007 FMP
Not yet reported French Innovative Leukemia Organisation 178 participants Est. completion 2013-07 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00565981
A Pilot Trial With Subcutaneous Alemtuzumab and Oral Fludarabinephosphate for the Determination of Safety, Efficacy and Molecular Profiling for the Prediction of Response
Not yet reported Arbeitsgemeinschaft medikamentoese Tumortherapie 10 participants Est. completion 2008-02-13 8 sites Stand-aloneOther conditions: B-cell Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00566332
Trial Comparing Chlorambucil to Fludarabine in Patients With Advanced Waldenström Macroglobulinemia
Not yet reported French Study Group on Chronic Lymphoid Leukemia 414 participants Est. completion 2014-12 1 siteOther conditions: Waldenström Macroglobulinemia, Lymphoplasmacytic Lymphoma, Splenic Marginal Zone LymphomaView official trial listing → -
Completed NCT NCT00566696
Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies
Not yet reported St. Jude Children's Research Hospital 73 participants Est. completion 2020-02-06 1 site Stand-aloneOther conditions: Leukemia, Acute Lymphocytic (ALL), Leukemia, Myeloid, Acute(AML), Leukemia, Myeloid, Chronic(CML), Juvenile Myelomonocytic Leukemia (JMML), Hemoglobinuria, Paroxysmal Nocturnal (PNH), Hodgkin Lymphoma, Lymphoma, Non-Hodgkin (NHL), Myelodysplastic Syndrome (MDS)View official trial listing → -
Completed NCT NCT00574496
Combination Chemotherapy Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or High-Risk Primary Refractory Hodgkin Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 25 participants Est. completion 2022-08-02 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Withdrawn NCT NCT00577161
Fludarabine, Pixantrone and Rituximab vs Fludarabine and Rituximab forRelapsed or Refractory Indolent NHL
Not yet reported CTI BioPharma Est. completion 2012-07 8 sites Stand-aloneOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT00577278
A Phase II Study of Allo-HCT for B-Cell NHL Using Zevalin, Fludarabine and Melphalan
Not yet reported City of Hope Medical Center 41 participants Est. completion 2023-12-14 1 site Stand-aloneOther conditions: Graft Versus Host Disease, Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00577993
Fludarabine, Mitoxantrone, and Dexamethasone (FND) Plus Rituximab for Lymphoma Patients
Not yet reported M.D. Anderson Cancer Center 210 participants Est. completion 2017-08-24 1 siteOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT00578292
Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO
Not yet reported Baylor College of Medicine 10 participants Est. completion 2016-05 1 site Stand-aloneOther conditions: ThalassemiaView official trial listing → -
Completed NCT NCT00578643
Matched Unrelated or Non-Genotype Identical Related Donor Transplantation For Chronic Granulomatous Disease
Not yet reported Baylor College of Medicine 15 participants Est. completion 2017-11-24 1 site Stand-aloneOther conditions: Chronic Granulomatous DiseaseView official trial listing → -
Completed NCT NCT00578942
Allo Non-myeloablative SCT Utilizing Matched Family Member Stem Cells Purged Using Campath
Not yet reported David Rizzieri, MD 48 participants Est. completion 2013-04 1 site Stand-aloneOther conditions: Lymphoma, Myeloma, Leukemia, Myelodysplasia, Solid TumorsView official trial listing → -
Terminated NCT NCT00579111
Reduced Intensity Preparative Regimen Followed by Stem Cell Transplant (FAB)
Not yet reported, Not yet reported Baylor College of Medicine 4 participants Est. completion 2010-10 2 sites Stand-aloneOther conditions: Myelodysplastic and Myeloproliferative Disorders, Acute Myelogenous Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, Multiple Myeloma, Plasma Cell Dyscrasia, Lymphoproliferative Disorders, Hematologic DiseasesView official trial listing → -
Terminated NCT NCT00579137
Allogeneic SCT Of Pts With SCID And Other Primary Immunodeficiency Disorders
Not yet reported, Not yet reported Baylor College of Medicine 3 participants Est. completion 2009-10 1 site Stand-aloneOther conditions: Severe Combined Immunodeficiency Disease, Severe Primary Immunodeficiency Disorder, Undefined T Cell Deficiency Disorder, Wiskott-Aldrick SyndromeView official trial listing → -
Completed NCT NCT00580034
Allo Non-Myeloablative SCT Utilizing Mis-Matched Family Member Stem Cells Purged Using Campath
Not yet reported David Rizzieri, MD 176 participants Est. completion 2013-04 1 site Stand-aloneOther conditions: Lymphoma, Myeloma, Leukemia, Myelodysplasia, Solid TumorsView official trial listing → -
Terminated NCT NCT00582816
Haploidentical Transplant With NK Cell Infusion for Pediatric Acute Leukemia and Solid Tumors
Not yet reported, Not yet reported University of Wisconsin, Madison 9 participants Est. completion 2015-08 1 site Stand-aloneOther conditions: Leukemia, Solid TumorsView official trial listing → -
Completed NCT NCT00582894
Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation for Malignant Hematological Diseases
Not yet reported University of Oklahoma 17 participants Est. completion 2008-03 1 siteOther conditions: Hematological Neoplasms, Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT00582933
Phase II Trial of a Chemotherapy Alone Regimen of IV Busulfan (Busulfex), Melphalan and Fludarabine as Myeloablative Regimen Followed by an Allogeneic T-Cell Depleted Hematopoietic Stem Cell Transplant From an HLA-Identical, or HLA-Non Identical Related or Unrelated Donor
Not yet reported Memorial Sloan Kettering Cancer Center 96 participants Est. completion 2009-04 1 site Stand-aloneOther conditions: Leukemia, Myelodysplastic Syndrome, Non-Hodgkin's Lymphoma, Allogeneic Marrow TransplantView official trial listing → -
Terminated NCT NCT00586274
Use of Rft5-Dga to Deplete Alloreactive Cells for Pts With Fanconi Anemia After Haploidentical SCT
Not yet reported Baylor College of Medicine 1 participants Est. completion 2009-07 2 sites Stand-aloneOther conditions: FANCONI ANEMIAView official trial listing → -
Completed NCT NCT00587054
Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic Disorders
Not yet reported Memorial Sloan Kettering Cancer Center 129 participants Est. completion 2011-05 1 site Stand-aloneOther conditions: Allogeneic Stem Cell Transplant, Leukemia, Non-Hodgkins, Lymphoblastic Lymphoma, Myelodysplastic Syndrome, Paroxysmal Nocturnal Hemoglobinuria (PNH)View official trial listing → -
Terminated NCT NCT00589316
Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome
Not yet reported Fred Hutchinson Cancer Center 26 participants Est. completion 2021-10-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, CD45-Positive Neoplastic Cells Present, Chronic Myelomonocytic Leukemia, Previously Treated Myelodysplastic Syndrome, Refractory Anemia With Excess Blasts, Refractory Anemia With Ring Sideroblasts, Refractory Cytopenia With Multilineage Dysplasia, Refractory Cytopenia With Multilineage Dysplasia and Ring SideroblastsView official trial listing → -
Completed NCT NCT00589563
Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant For Hematological Cancer
Not yet reported City of Hope Medical Center 32 participants Est. completion 2012-02 2 sites Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Infection, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Precancerous Condition, Secondary Myelofibrosis, Small Intestine CancerView official trial listing → -
Terminated NCT NCT00590460
Antibody Conditioning Regimen For Allogeneic Donor Stem Cell Transplantation Of Patients With Fanconi Anemia
Not yet reported, Not yet reported Baylor College of Medicine 5 participants Est. completion 2009-09 2 sites Stand-aloneOther conditions: Fanconi Anemia, Severe Aplastic AnemiaView official trial listing → -
Terminated NCT NCT00593554
Phase 2 Haplotype Mismatched HSCT in Patients With Hematological Malignancies
Not yet reported Sherif S. Farag 9 participants Est. completion 2017-07-28 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplasia, Chronic Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT00594308
In-Vivo Activated T-Cell Depletion to Prevent GVHD
Not yet reported Indiana University 10 participants 1 siteOther conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Myelodysplasia, Lymphoma, Non-Hodgkin's, Mantle-Cell Lymphoma, Hodgkin's Disease, Multiple Myeloma, MyelofibrosisView official trial listing → -
Completed NCT NCT00595127
Hematopoietic Stem Cell Transplantation for Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using Total Body Irradiation, Cyclophosphamide and Fludarabine
Not yet reported Memorial Sloan Kettering Cancer Center 21 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Fanconi AnemiaView official trial listing → -
Completed NCT NCT00597519
A Myeloablative Conditioning Regimen and Total Body Irradiation Followed by the Transplantation for Patients With Hematological Malignancy
Not yet reported Memorial Sloan Kettering Cancer Center 28 participants Est. completion 2015-09 1 site Stand-aloneOther conditions: Cancer, Leukemia, Myelodysplastic Syndrome, Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT00597714
Efficacy Study of T Cell Depleted Allogeneic Non-myeloablative Stem Cell Transplant
Not yet reported David Rizzieri, MD 264 participants Est. completion 2013-11 1 site Stand-aloneOther conditions: Hodgkin's Disease, Non Hodgkin's Lymphoma, Myeloma, Leukemia, MyelodysplasiaView official trial listing → -
Completed NCT NCT00602459
Fludarabine and Rituximab With or Without Lenalidomide or Cyclophosphamide in Treating Patients With Symptomatic Chronic Lymphocytic Leukemia
Not yet reported National Cancer Institute (NCI) 418 participants Est. completion 2023-04-15 364 sites Stand-aloneOther conditions: Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage IV Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00602693
T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer
Not yet reported Masonic Cancer Center, University of Minnesota 41 participants Est. completion 2015-04-16 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma, Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Withdrawn NCT NCT00603460
DCVax-L Vaccination With CD3/CD28 Costimulated Autologous T-Cells for Recurrent Ovarian or Primary Peritoneal Cancer
Not yet reported, Not yet reported University of Pennsylvania Est. completion 2013-03 1 siteOther conditions: Ovarian Cancer, Primary Peritoneal CancerView official trial listing → -
Completed NCT NCT00603954
Allogeneic HCT With HLA-matched Donors : a Phase II Randomized Study Comparing 2 Nonmyeloablative Conditionings
Not yet reported University of Liege 107 participants Est. completion 2016-07 11 sitesOther conditions: Hematological MalignanciesView official trial listing → -
Status unknown NCT NCT00604136
Treatment of Metastatic Melanoma With Tumor Infiltrating Lymphocytes and IL-2 Following Lympho-depleting Chemotherapy
Not yet reported Hadassah Medical Organization 20 participants Est. completion 2020-07 1 siteOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT00606437
Total Body Irradiation With Fludarabine Followed by Combined Umbilical Cord Blood (UCB) Transplants
Not yet reported Duke University 40 participants Est. completion 2014-02 1 site Stand-aloneOther conditions: Lymphoma, Myeloma, Leukemia, Myelodysplasia, Solid Tumors, Hodgkin's Disease, MyelofibrosisView official trial listing → -
Completed NCT NCT00607854
Safety of Ibritumomab Tiuxetan (Zevalin®) in Combination With a Fludarabine-based Reduced Intensity Conditioning (RIC) Regimen (ZEVALLO 2007)
Not yet reported University Hospital, Bordeaux 31 participants Est. completion 2011-11 12 sites Stand-aloneOther conditions: Diffuse Large B-Cell Lymphoma, Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT00608374
Chlorambucil or Fludarabine as First-Line Therapy in Treating Patients With Previously Untreated Waldenström Macroglobulinemia, Splenic Lymphoma, or Lymphoplasmacytic Lymphoma
Not yet reported Taunton and Somerset Hospital 400 participants Est. completion 2013-01 49 sitesOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT00608517
Treatment of Single or Double Umbilical Cord Trans + Graft-versus-host Disease (GVHD) Prophylaxis w/ Tacrolimus & Mycophenolate Mofetil
Not yet reported Vanderbilt-Ingram Cancer Center 6 participants Est. completion 2011-05 4 sites Stand-aloneOther conditions: Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00610311
Anti-gp100 Cells Plus ALVAC gp100 Vaccine to Treat Advanced Melanoma
Not yet reported National Cancer Institute (NCI) 3 participants Est. completion 2011-02 1 site Stand-aloneOther conditions: Metastatic Melanoma, Skin CancerView official trial listing → -
Terminated NCT NCT00612222
Anti-MART-1 F5 Cells Plus ALVAC MART-1 Vaccine to Treat Advanced Melanoma
Not yet reported National Cancer Institute (NCI) 4 participants Est. completion 2011-03 1 site Stand-aloneOther conditions: Metastatic Melanoma, Skin CancerView official trial listing → -
Terminated NCT NCT00612612
Obatoclax, Fludarabine, and Rituximab in Treating Patients With Previously Treated Chronic Lymphocytic Leukemia
Not yet reported National Cancer Institute (NCI) 28 participants 1 site Stand-aloneOther conditions: B-cell Chronic Lymphocytic Leukemia, Leukemia, Prolymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, Stage I Chronic Lymphocytic Leukemia, Stage II Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage IV Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT00613561
Early Diagnosis and Stem Cell Transplantation for Severe Immunodeficiency Diseases
Not yet reported Ann & Robert H Lurie Children's Hospital of Chicago 25 participants Est. completion 2017-12 1 siteOther conditions: Severe Immunodeficiency DiseasesView official trial listing → -
Terminated NCT NCT00615589
Stem Cell Transplantation To Treat High Risk Multiple Myeloma With Reduced Toxicity Myeloablative Conditioning Regimen
Not yet reported University of Michigan Rogel Cancer Center 22 participants Est. completion 2013-01 1 site Stand-aloneOther conditions: Multiple Myeloma, Plasma Cell LeukemiaView official trial listing → -
Terminated NCT NCT00618540
Reduced Intensity Hematopoietic Cell Transplantation for Patients With Resistant Langerhans Cell Histiocytosis
Not yet reported Masonic Cancer Center, University of Minnesota 1 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Histiocytosis, Langerhans-cellView official trial listing → -
Completed NCT NCT00619645
Donor Peripheral Stem Cell Transplant, Fludarabine, and Busulfan in Treating Patients With Hematologic Cancers
Not yet reported University of California, Davis 8 participants Est. completion 2013-11 1 siteOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00622895
Allogeneic Hematopoietic Cell Transplantation for Severe Systemic Sclerosis
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 3 participants Est. completion 2017-08-01 2 sites Stand-aloneOther conditions: Systemic Scleroderma, Severe Systemic SclerosisView official trial listing → -
Completed NCT NCT00623935
Blood Stem Cell Transplantation for the Treatment of Older Patients With Acute Myelogenous Leukemia
Not yet reported University of Michigan Rogel Cancer Center 56 participants Est. completion 2015-11 1 site Stand-aloneOther conditions: Acute Myelogenous LeukemiaView official trial listing → -
Status unknown NCT NCT00625430
A Phase I Gene Therapy Study of FP253/Fludarabine for Prostate Cancer
Not yet reported Biotech Equity Partners Pty Ltd 18 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00625729
Donor Natural Killer Cell Infusion, Rituximab, Aldesleukin, and Chemotherapy in Treating Patients With Relapsed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 6 participants Est. completion 2010-04 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT00627666
Donor Stem Cell Transplant After Busulfan, Fludarabine, and Antithymocyte Globulin in Treating Patients With Hematological Cancer
Not yet reported Asan Medical Center 52 participants Est. completion 2010-06 1 siteOther conditions: Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00629798
Busulfan, Melphalan, and Fludarabine With Peri-transplant Palifermin, Followed by a T-Cell Depleted Hematopoietic Stem Cell Transplant From HLA Matched or Mismatched Related or Unrelated Donors in Patients With Advanced Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)
Not yet reported Memorial Sloan Kettering Cancer Center 64 participants Est. completion 2020-10-20 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Advanced Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00630253
Cytoxan, Fludara, and Antithymocyte Globulin Conditioning Followed By Stem Cell Transplant in Treating Fanconi Anemia
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 31 participants Est. completion 2020-10-10 1 site Stand-aloneOther conditions: Fanconi AnemiaView official trial listing → -
Completed NCT NCT00634881
Alemtuzumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia
Not yet reported, Not yet reported German CLL Study Group 13 participants Est. completion 2012-02-17 6 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT00636155
EL625 in Persistent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported David Rizzieri 20 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: Lymphoma, Small Lymphocytic, Leukemia, Lymphocytic, ChronicView official trial listing → -
Completed NCT NCT00636909
Nonmyeloablative Allo SCT for the Treatment of Hematologic Disorders
Not yet reported Beth Israel Deaconess Medical Center 25 participants Stand-aloneOther conditions: AML, ALL, CML Chronic Phase, Accelerated Phase, or Blast Crisis, CLL, MDS, RELAPSED NON-HODGKIN'S OR HODGKIN'S LYMPHOMA, APLASTIC ANEMIA, MULTIPLE MYELOMA, MYELOPROLIFERATIVE DISORDER (P Vera, CMML, ET)View official trial listing → -
Completed NCT NCT00640796
Pilot Study of Expanded, Donor Natural Killer Cell Infusions for Refractory Non-B Lineage Hematologic Malignancies and Solid Tumors
Not yet reported St. Jude Children's Research Hospital 22 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute, T-Cell, Juvenile Myelomonocytic Leukemia Lymphoblastic, T-cell Lymphoblastic Lymphoma, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00641095
Phase III, Multicentre, Randomised Study of Fludarabine/Cyclophosphamide Combination With or Without Rituximab in Patients With Untreated Mantle Cell Lymphoma
Not yet reported, Not yet reported University College, London 370 participants Est. completion 2015-05-22 67 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00644371
Allogenic Stem Cell Transplantation (SCT) With Non-myeloablative Conditioning in Patients With Relapse Non-Hodgkin's Lymphoma (NHL)
Not yet reported Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea 20 participants Est. completion 2013-02-04 14 sites Stand-aloneOther conditions: Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT00645606
Rituximab Maintenance Versus Observation After First-line Immunochemotherapy by FCR in Older Patients With Chronic Lymphocytic Leukemia
Not yet reported University Hospital, Tours 542 participants Est. completion 2017-07 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00651781
Velcaflagida in Relapsed or Refractary Acute Myeloid Leukemia
Not yet reported, Not yet reported PETHEMA Foundation 40 participants Est. completion 2013-02 13 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT00652899
Allogeneic Natural Killer Cells in Patients With Recurrent Ovarian Cancer, Fallopian Tube, and Primary Peritoneal Cancer
Not yet reported Masonic Cancer Center, University of Minnesota 14 participants Est. completion 2009-08 1 site Stand-aloneOther conditions: Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity CancerView official trial listing → -
Terminated NCT NCT00670410
Autologous Transplant Followed by Allogeneic Transplant for High Risk Neuroblastoma
Not yet reported Columbia University 15 participants Est. completion 2010-12 1 site Stand-aloneOther conditions: NeuroblastomaView official trial listing → -
Terminated NCT NCT00670748
Chemotherapy Followed by ESO-1 Lymphocytes and Aldesleukin to Treat Metastatic Cancer
Not yet reported National Cancer Institute (NCI) 45 participants Est. completion 2016-06-29 1 site Stand-aloneOther conditions: Metastatic Melanoma, Metastatic Renal Cell Cancer, Metastatic CancerView official trial listing → -
Terminated NCT NCT00676806
A Phase II Study of Umbilical Cord Blood Transplantation
Not yet reported Tufts Medical Center 7 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma, Aplastic AnemiaView official trial listing → -
Status unknown NCT NCT00679536
Allogeneic Transplantation for Pediatric Leukemias With Unrelated Donors
Not yet reported, Not yet reported Ann & Robert H Lurie Children's Hospital of Chicago 30 participants Est. completion 2015-05 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00683046
T-Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Hematologic Malignancies
Not yet reported University of Chicago 204 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Lymphoid Leukemia, Chronic Myelogenous Leukemia, Malignant Lymphoma, Hodgkin's Disease, Chronic Lymphocytic Leukemia, Myeloproliferative Disorder, Anemia, Aplastic, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00684255
Reduced Intensity Transplant in Medically Refractory Systemic Lupus Erythematosus (SLE) and Systemic Sclerosis (SSc)
Not yet reported New York Medical College 1 participants Est. completion 2008-07 1 site Stand-aloneOther conditions: Systemic Lupus Erythematosus, Systemic SclerosisView official trial listing → -
Completed NCT NCT00686556
Total Marrow Irradiation for Refractory Acute Leukemia
Not yet reported Masonic Cancer Center, University of Minnesota 12 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, Multiple MyelomaView official trial listing → -
Completed NCT NCT00688883
Fludara (Oral) Phase II Study for Indolent Lymphoma
Not yet reported Genzyme, a Sanofi Company 52 participants Est. completion 2004-08 17 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00691015
Sirolimus, Tacrolimus, and Antithymocyte Globulin in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplant
Not yet reported Barbara Ann Karmanos Cancer Institute 48 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00693927
Nonmyeloablative Stem Cell Transplantation With CD8-depleted or Unmanipulated Peripheral Blood Stem Cells (PBSC)
Not yet reported University of Liege 54 participants Est. completion 2008-05 1 siteOther conditions: Hematologic MalignanciesView official trial listing → -
Terminated NCT NCT00698009
Haploidentical Natural Killer (NK) Cells in Patients With Relapsed or Refractory Neuroblastoma
Not yet reported M.D. Anderson Cancer Center 1 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: NeuroblastomaView official trial listing → -
Terminated NCT NCT00704938
Gene-Modified Lymphocytes, High-Dose Aldesleukin, and Vaccine Therapy in Treating Patients With Progressive or Recurrent Metastatic Cancer
Not yet reported National Institutes of Health Clinical Center (CC) 3 participants Est. completion 2009-08 1 site Stand-aloneOther conditions: Kidney Cancer, Melanoma (Skin), Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Terminated NCT NCT00708721
Low-dose Oral Clofarabine for the Treatment of IPSS INT-1, INT-2 or HIGH Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia
Not yet reported, Not yet reported University of Utah 11 participants Est. completion 2014-11 1 site Stand-aloneOther conditions: Cancer, Chronic Myelomonocytic LeukemiaView official trial listing → -
Terminated NCT NCT00714259
Non-Myeloablative Allogeneic HSCT From HLA Matched Related or Unrelated Donors for the Treatment of Low Grade B Cell Malignancies
Not yet reported, Not yet reported University of Alabama at Birmingham 5 participants Est. completion 2013-02 1 siteOther conditions: Multiple Myeloma, CLL / SLL, Non Hodgkin's Lymphoma, Waldenstroms, Mantle Cell LymphomaView official trial listing → -
Terminated NCT NCT00719849
Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematological Cancer or Other Disease
Not yet reported Fred Hutchinson Cancer Center 13 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00719888
Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Disease
Not yet reported Fred Hutchinson Cancer Center 135 participants Est. completion 2024-12-19 3 sites Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Burkitt Lymphoma, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Follicular Lymphoma, Lymphoblastic Lymphoma, Lymphoplasmacytic Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Myelodysplastic Syndrome, Myelofibrosis, Non-Hodgkin Lymphoma, Plasma Cell Myeloma, Prolymphocytic Leukemia, Refractory Anemia, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT00723099
Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer
Not yet reported Fred Hutchinson Cancer Center 73 participants Est. completion 2018-07-31 6 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Aggressive Non-Hodgkin Lymphoma, Chronic Myelogenous Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Indolent Non-Hodgkin Lymphoma, Lymphoma, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Recurrent Chronic Lymphocytic Leukemia, Recurrent Follicular Lymphoma, Recurrent Lymphoplasmacytic Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Plasma Cell Myeloma, Recurrent Small Lymphocytic Lymphoma, Recurrent T-Cell Non-Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Chronic Myelogenous Leukemia, Refractory Follicular Lymphoma, Refractory Hodgkin Lymphoma, Refractory Lymphoplasmacytic Lymphoma, Refractory Mantle Cell Lymphoma, Refractory Small Lymphocytic Lymphoma, T-Cell Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT00727415
Lenalidomide, Fludarabine & Cyclophosphamide in Advanced Chronic Lymphocytic Leukemia Not Responding to Therapy
Not yet reported, Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 42 participants Est. completion 2016-01 23 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00731328
Donor Stem Cell Transplant After Busulfan, Fludarabine, Methylprednisolone, and Antithymocyte Globulin in Treating Patients With Bone Marrow Failure Syndrome
Not yet reported Asan Medical Center 15 participants Est. completion 2013-12 1 siteOther conditions: Leukemia, Myelodysplastic Syndromes, Nonmalignant Neoplasm, Paroxysmal Nocturnal HemoglobinuriaView official trial listing → -
Completed NCT NCT00732316
Donor Stem Cell Transplant After Busulfan, Fludarabine, and Antithymocyte Globulin in Treating Patients With Hematologic Cancer or Myelodysplastic Syndrome
Not yet reported Asan Medical Center 54 participants Est. completion 2011-05 1 siteOther conditions: Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT00737685
Flu+CPM+rATG Conditioning Regimes for Unrelated Bone Marrow Transplantation (UBMT)(or Mobilized Peripheral Blood)in Severe Aplastic Anemia (SAA)
Not yet reported The Korean Society of Pediatric Hematology Oncology 30 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Anemia, AplasticView official trial listing → -
Completed NCT NCT00738829
Lenalidomide Dose Escalation Combined With Rituximab/Fludarabine in Untreated CLL
Not yet reported, Not yet reported Arbeitsgemeinschaft medikamentoese Tumortherapie 45 participants Est. completion 2012-01 7 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Completed NCT NCT00739141
Conditioning Regimen and the Transplantation of Unrelated Donor Umbilical Cord Blood in Patients With Hematologic Malignancies.
Not yet reported Memorial Sloan Kettering Cancer Center 86 participants Est. completion 2021-10-15 1 site Stand-aloneOther conditions: Leukemia, Myelodysplastic Syndrome, Non-Hodgkins Lymphoma, Chronic Myelogenous Leukemia, Hodgkins LymphomaView official trial listing → -
Completed NCT NCT00741455
Chemotherapy Followed by Allogeneic Stem Cell Transplantation for Hematologic Malignancies
Not yet reported Dartmouth-Hitchcock Medical Center 18 participants Est. completion 2020-05-01 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT00744692
Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders
Not yet reported Duke University 22 participants Est. completion 2014-04 1 siteOther conditions: Non Malignant Disorders, Immunodeficiencies, Congenital Marrow Failures, Hemoglobinopathies, Inborn Errors of Metabolism, Sickle Cell, Thalassemia, Lysosomal Storage DiseaseView official trial listing → -
Completed NCT NCT00745420
Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601)
Not yet reported Medical College of Wisconsin 30 participants Est. completion 2016-09 19 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Status unknown NCT NCT00750126
Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported University Hospital, Clermont-Ferrand 30 participants Est. completion 2009-04 1 siteOther conditions: Solid Tumors, Hematologic NeoplasmsView official trial listing → -
Completed NCT NCT00759798
Identifying Prognostic Factors in Frontline FCR for Patients With Chronic Lymphocytic Leukemia (CLL)
Not yet reported M.D. Anderson Cancer Center 289 participants Est. completion 2020-07-22 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, LeukemiaView official trial listing → -
Completed NCT NCT00763490
Trial Of Double Umbilical Cord Blood Transplantation
Not yet reported University of Michigan Rogel Cancer Center 20 participants Est. completion 2015-10 1 site Stand-aloneOther conditions: Hematological MalignanciesView official trial listing → -
Completed NCT NCT00764829
Blood Samples to Evaluate Biomarkers of Donor Chimerism
Fred Hutchinson Cancer Center 80 participants Est. completion 2012-02 1 siteOther conditions: Leukemia, Hodgkins Disease, Non-hodgkins Lymphoma, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00769522
FCR or BR in Patients With Previously Untreated B-Cell Chronic Lymphocytic Leukemia
Not yet reported German CLL Study Group 564 participants Est. completion 2018-01 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00772486
A Phase Ib Study of ISF35 in Combination With Chemotherapy (FCR) in Subjects With Relapsed, Refractory, and/or 17p- CLL
Not yet reported Memgen, LLC 13 participants Est. completion 2013-04 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00774280
Busulfan Plus Cyclophosphamide vs Fludarabine as a Conditioning Regimen
Not yet reported Cooperative Study Group A for Hematology 130 participants Est. completion 2010-12 1 siteOther conditions: Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00774527
Comparison of Cy-Atg Vs Cy-Flu-Atg for the Conditioning Therapy in Allo-HCT
Not yet reported Cooperative Study Group A for Hematology 82 participants Est. completion 2011-01 1 siteOther conditions: Bone Marrow Failure SyndromesView official trial listing → -
Status unknown NCT NCT00774826
Multicentric Study, Three Randomized Arms (R-CVP vs R-CHOP vs R-FM),for Patients With Stage II-IV Follicular Lymphoma
Not yet reported Fondazione Italiana Linfomi - ETS 534 participants Est. completion 2014-03 82 sitesOther conditions: Follicular LymphomaView official trial listing → -
Completed NCT NCT00775931
Allogeneic Transplantation For Severe Osteopetrosis
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 7 participants Est. completion 2013-06 1 siteOther conditions: Severe OsteopetrosisView official trial listing → -
Completed NCT NCT00782379
Combination Chemotherapy, Donor Stem Cell Transplant, Tacrolimus, Mycophenolate Mofetil, and Cyclophosphamide in Treating Patients With Hematologic Cancer
Not yet reported Northside Hospital, Inc. 20 participants Est. completion 2012-04 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT00787761
Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer
Not yet reported Northside Hospital, Inc. 24 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: Myeloproliferative Disorders, Kidney Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00789776
Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolimus in Treating Patients With Hematologic Cancer
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 41 participants Est. completion 2017-05 3 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Aggressive Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma, Previously Treated Myelodysplastic Syndrome, Recurrent Chronic Lymphocytic Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Indolent Adult Non-Hodgkin Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Plasma Cell Myeloma, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hodgkin Lymphoma, Refractory Plasma Cell Myeloma, Refractory Small Lymphocytic Lymphoma, Waldenstrom MacroglobulinemiaView official trial listing → -
Status unknown NCT NCT00790413
Haploidentical Stem Cell Transplantation in Neuroblastoma
Not yet reported Lund University Hospital 15 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: NeuroblastomaView official trial listing → -
Completed NCT NCT00793351
Reduced Intensity Stem Cell Transplantation in Children With Relapsed Neuroblastoma After Autologous Transplantation
Not yet reported Samsung Medical Center 25 participants Est. completion 2015-11 1 siteOther conditions: NeuroblastomaView official trial listing → -
Completed NCT NCT00793572
Autologous or Syngeneic Stem Cell Transplant Followed by Donor Stem Cell Transplant and Bortezomib in Treating Patients With Newly Diagnosed High-Risk, Relapsed, or Refractory Multiple Myeloma
Not yet reported Fred Hutchinson Cancer Center 32 participants Est. completion 2016-10 1 site Stand-aloneOther conditions: Refractory Plasma Cell MyelomaView official trial listing → -
Completed NCT NCT00794820
Fludarabine, Cyclophosphamide, and Rituximab - High Dose Frontline
Not yet reported M.D. Anderson Cancer Center 66 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00795132
Hematopoietic Cell Transplantation for Pediatric Patients With Hematologic Malignancies
Not yet reported University of Utah 47 participants Est. completion 2009-07 1 siteOther conditions: Acute Leukaemia, Chronic Disease, Leukemia, Myelodysplasia, LymphomaView official trial listing → -
Completed NCT NCT00796068
Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematological Cancer Who Are Undergoing Umbilical Cord Blood Transplant
Not yet reported Fred Hutchinson Cancer Center 130 participants Est. completion 2021-12-14 3 sites Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission, Blasts Under 5 Percent of Bone Marrow Nucleated Cells, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Myelodysplastic Syndrome (MDS)View official trial listing → -
Terminated NCT NCT00800150
Total Marrow and Total Lymph Node Irradiation, Fludarabine, and Melphalan Followed By Donor Stem Cell Transplant in Treating Patients With Advanced Hematological Cancer That Has Not Responded to Treatment
Not yet reported City of Hope Medical Center 6 participants Est. completion 2010-10 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT00800839
Busulfan and Fludarabine Followed by Post-transplant Cyclophosphamide
Not yet reported M.D. Anderson Cancer Center 56 participants 1 site Stand-aloneOther conditions: Hematologic Diseases, Leukemia, Lymphoma, MyelomaView official trial listing → -
Terminated NCT NCT00801060
Evaluation of Safety and Efficacy of Fludarabine, Cyclophosphamide, and Rituximab (FCR) +/- Lumiliximab in Subjects With Previously Untreated Chronic Lymphocytic Leukemia (CLL)
Not yet reported Biogen 40 participants Est. completion 2010-09 36 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00802113
Autologous and Allogeneic Transplant for Relapsed Lymphoma
Not yet reported, Not yet reported Columbia University 30 participants Est. completion 2014-10-22 6 sites Stand-aloneOther conditions: Non-Hodgkin's Lymphoma, Hodgkins DiseaseView official trial listing → -
Completed NCT NCT00802568
Fludarabine, Busulfan, Antithymocyte Globulin, and Donor Stem Cell Transplant in Treating Patients With Multiple Myeloma That Has Not Responded to Treatment
Not yet reported Institut Paoli-Calmettes 48 participants 1 siteOther conditions: Multiple Myeloma and Plasma Cell NeoplasmView official trial listing → -
Completed NCT NCT00806767
Fludarabine, Busulfan, and Antilymphocyte Globulin Followed by Donor Stem Cell Transplant in Treating Older Patients With Hematological Cancer
Not yet reported Institut Paoli-Calmettes 82 participants 1 siteOther conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Status unknown NCT NCT00807196
Zevalin With Non Myeloablative Allogeneic Stem Cell Transplantation in Patients With Non Hodgkin Lymphoma
Not yet reported, Not yet reported Maisonneuve-Rosemont Hospital 20 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Non-Hodgkins LymphomaView official trial listing → -
Completed NCT NCT00809276
Allo BMT Using Matched Related/Unrelated Donors With FluBu and HiCY
Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 92 participants Est. completion 2011-12 3 sitesOther conditions: Lymphoma, Multiple Myeloma, Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00810602
Vorinostat to Prevent Graft Versus Host Disease Following Reduced Intensity, Related Donor Stem Cell Transplant
Not yet reported, Not yet reported Pavan Reddy, MD 61 participants Est. completion 2013-07 2 sites Stand-aloneOther conditions: Hematologic Malignancies, Graft vs Host DiseaseView official trial listing → -
Completed NCT NCT00812669
CLL-Irl Study. CTRIAL-IE (ICORG) 07-01, V7
Not yet reported Cancer Trials Ireland 52 participants Est. completion 2019-11-21 7 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT00813124
Azacitidine After Allo Blood And Marrow Transplantation (BMT) for Chronic Myelogenous Leukemia (CML)
Not yet reported M.D. Anderson Cancer Center 24 participants Est. completion 2014-09 1 site Stand-aloneOther conditions: Stem Cell Transplantation, LeukemiaView official trial listing → -
Status unknown NCT NCT00815568
Feasibility and Efficacy Study of Conditioning Regimen for Allogeneic Hematopoietic Cell Transplantation (HCT) With Fludarabine, Busulfan, and Total Body Irradiation (TBI)
Not yet reported Samsung Medical Center 114 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: AML, MDS, ALL, CML, LymphomaView official trial listing → -
Terminated NCT NCT00818961
Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Cancer
Not yet reported Northside Hospital, Inc. 36 participants Est. completion 2012-03 1 siteOther conditions: Leukemia, Lymphoma, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT00822770
Plerixafor and Granulocyte Colony-stimulating Factor (G-CSF) With Busulfan, Fludarabine and Thymoglobulin
Not yet reported, Not yet reported M.D. Anderson Cancer Center 47 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: Stem Cell Transplantation, LeukemiaView official trial listing → -
Completed NCT NCT00824265
Ofatumumab Added to Fludarabine-Cyclophosphamide vs Fludarabine-Cyclophosphamide Combination in Relapsed Subjects With Chronic Lymphocytic Leukemia
Not yet reported Novartis Pharmaceuticals 365 participants Est. completion 2017-10-25 135 sites Stand-aloneOther conditions: Leukaemia, Lymphocytic, ChronicView official trial listing → -
Withdrawn NCT NCT00829647
A Study Using Two Oral Chemotherapy Agents for Chronic Lymphocytic Leukemia
Not yet reported, Not yet reported Scripps Health Est. completion 2016-03-01Other conditions: Chronic Lymphocytic Leukemia, LeukemiaView official trial listing → -
Status unknown NCT NCT00840385
Orally Fludarabine, Adriamycin and Dexamethasone (FAD) in Newly Diagnosed Peripheral T-cell Lymphomas (PTCL)
Not yet reported Fudan University 30 participants Est. completion 2010-11 1 site Stand-aloneOther conditions: T-Cell Lymphomas, ChemotherapyView official trial listing → -
Completed NCT NCT00841724
Study of a Reduced-toxicity "Submyeloablative" Conditioning Regimen Prior to Allogeneic Stem Cell Transplantation in Patients With Hematological Malignancies
Not yet reported Nantes University Hospital 82 participants Est. completion 2012-01 3 sitesOther conditions: Hematological MalignanciesView official trial listing → -
Completed NCT NCT00843947
Reduced Intensity Stem Cell Transplantation (RIST) for Patients With Hematological Malignancies Conditioned With Fludarabine and Busulfan
Not yet reported University of California, Davis 8 participants Est. completion 2013-11 1 siteOther conditions: Hematologic MalignanciesView official trial listing → -
Withdrawn NCT NCT00845104
Fludarabine Phosphate, Rituximab, and Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia That Has Relapsed or Not Responded To Treatment
Not yet reported Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium Stand-aloneOther conditions: B-cell Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00849147
Bone Marrow Transplant From Partially Matched Donors and Nonmyeloablative Conditioning for Blood Cancers (BMT CTN 0603)
Not yet reported Medical College of Wisconsin 55 participants Est. completion 2013-11 17 sites Stand-aloneOther conditions: Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Acute, Burkitt Lymphoma, Lymphoma, B-Cell, Lymphoma, Follicular, Lymphoma, Large B-Cell, DiffuseView official trial listing → -
Terminated NCT NCT00849745
Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases
Not yet reported Duke University 4 participants Est. completion 2015-07 1 site Stand-aloneOther conditions: Systemic Lupus Erythematosus, Systemic SclerosisView official trial listing → -
Terminated NCT NCT00850499
Phase 2 Study of VELCADE With Fludarabine in Comparison to Rituximab With Fludarabine in Follicular Lymphoma Patients Previously Treated With Rituximab
Not yet reported Millennium Pharmaceuticals, Inc. 12 participants Est. completion 2011-10 43 sites Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Completed NCT NCT00852163
Study of Stem Cell Transplant for Leukemia and Myelodysplastic Syndromes Using Clofarabine and Busulfan Regimen
Not yet reported Baylor Research Institute 20 participants Est. completion 2011-12 1 siteOther conditions: Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00856388
Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders
Not yet reported Roswell Park Cancer Institute 62 participants Est. completion 2019-03-13 1 site Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Aplastic Anemia, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Eosinophilic Leukemia, Chronic Myelomonocytic Leukemia, Chronic Neutrophilic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, de Novo Myelodysplastic Syndromes, Fanconi Anemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Burkitt Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Grade 1 Follicular Lymphoma, Noncontiguous Stage II Grade 2 Follicular Lymphoma, Noncontiguous Stage II Grade 3 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Noncontiguous Stage II Marginal Zone Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Paroxysmal Nocturnal Hemoglobinuria, Previously Treated Myelodysplastic Syndromes, Primary Myelofibrosis, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Splenic Marginal Zone Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Small Lymphocytic Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Small Lymphocytic Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT00859001
Study to Evaluate the Efficacy and Safety of Subsequent Treatment With the Zevalin (Ibritumomab Tiuxetan) Study in Patients With Follicular Grade I-II Lymphoma After 4 Cycles of Fludarabine-Mitoxantrone-Rituximab (FMR) Therapy
Not yet reported University of Bologna 55 participants 1 site Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Completed NCT NCT00860457
Lenalidomide Following Fludarabine/Rituximab (FR) in Untreated Chronic Lymphocytic Leukemia (CLL)
Not yet reported Georgetown University 22 participants Est. completion 2012-02 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00860574
Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia
Not yet reported Fred Hutchinson Cancer Center 96 participants 3 sites Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Blastic Phase Chronic Myelogenous Leukemia, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT00863330
Laboratory-Treated Autologous Lymphocytes and Aldesleukin After Cyclophosphamide and Fludarabine in Treating Patients With Metastatic Melanoma
Not yet reported Wake Forest University Health Sciences 14 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Melanoma (Skin)View official trial listing → -
Completed NCT NCT00864227
Evaluating the Safety and Effectiveness of an Umbilical Cord Blood Stem Cell Transplant (BMT CTN 0604)
Not yet reported Medical College of Wisconsin 54 participants Est. completion 2013-11 16 sites Stand-aloneOther conditions: Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myeloid, Acute, Burkitt Lymphoma, Lymphoma, B-Cell, Lymphoma, Follicular, Lymphoma, Large B-Cell, DiffuseView official trial listing → -
Completed NCT NCT00868413
Study of ABT-263 When Administered in Combination With Either Fludarabine/Cyclophosphamide/Rituximab or Bendamustine/Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia
Not yet reported AbbVie (prior sponsor, Abbott) 32 participants Est. completion 2013-05 6 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT00871689
Chemotherapy, Total-Body Irradiation, Donor Natural Killer Cell Infusion, Aldesleukin, and UCB Transplant in Treating Patients With Relapsed or Refractory AML
Not yet reported Masonic Cancer Center, University of Minnesota 2 participants Est. completion 2011-10 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Withdrawn NCT NCT00874315
Allogeneic Hematopoietic Stem Cell Transplantation for Relapsed or Refractory High-Risk NBL.
Not yet reported Nationwide Children's Hospital Est. completion 2012-06 4 sitesOther conditions: NeuroblastomaView official trial listing → -
Completed NCT NCT00875667
A Study to Determine the Efficacy of Lenalidomide Versus Investigator's Choice in Patients With Relapsed or Refractory Mantle Cell Lymphoma (MCL)
Not yet reported Celgene 254 participants Est. completion 2018-10-09 97 sitesOther conditions: Mantle Cell Lymphoma, Lymphoma, Mantle-CellView official trial listing → -
Completed NCT NCT00880815
Fludarabine, Bendamustine, and Rituximab in Treating Participants With Lymphoid Cancers Undergoing Stem Cell Transplant
Not yet reported M.D. Anderson Cancer Center 60 participants Est. completion 2019-05-28 1 site Stand-aloneOther conditions: CD20 Positive, Chronic Lymphocytic Leukemia, Follicular Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, T-Cell Non-Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT00881556
Allogeneic Stem Cell Transplantation (ALLOSCT) in Recessive Dystrophic Epidermolysis Bullosa (RDEB)
Not yet reported Columbia University 3 participants Est. completion 2015-09 3 sites Stand-aloneObstructive sleep apneaView official trial listing → -
Active, not recruiting NCT NCT00881920
Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL
Not yet reported Baylor College of Medicine 54 participants Est. completion 2035-07 2 sites Stand-aloneOther conditions: Lymphoma, Myeloma, LeukemiaView official trial listing → -
Status unknown NCT NCT00881933
Study of Fludarabine + Cyclophosphamide + TBI Conditioning Regimen for Double Units Cord Blood Transplantation(CBT)in Severe Aplastic Anemia(SAA)
Not yet reported, Not yet reported The Korean Society of Pediatric Hematology Oncology 5 participants Est. completion 2012-09 1 site Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Status unknown NCT NCT00882323
Reduced Toxicity Fludarabine (Flu) + Cyclophosphamide (CPM) + Rabbit Antithymocyte Globulin (rATG) Conditioning Regimen for Unrelated Donor Transplantation in Severe Aplastic Anemia (SAA)
Not yet reported The Korean Society of Pediatric Hematology Oncology 33 participants Est. completion 2012-10 1 site Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Completed NCT NCT00885833
Study of Reduced Toxicity Myeloablative Conditioning Regimen for Wiskott-Aldrich Syndrome (WAS)
Not yet reported, Not yet reported The Korean Society of Pediatric Hematology Oncology 5 participants Est. completion 2012-03 1 site Stand-aloneOther conditions: Wiskott-Aldrich SyndromeView official trial listing → -
Completed NCT NCT00886522
Intrabone Infusion of Cord Blood in Adults With Hematological Malignancies
Not yet reported IRCCS Azienda Ospedaliero-Universitaria di Bologna 23 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Hematological MalignanciesView official trial listing → -
Status unknown NCT NCT00887042
Study of Reduced Toxicity Myeloablative Conditioning Regimen for Cord Blood Transplantation in Pediatric AML
Not yet reported, Not yet reported The Korean Society of Pediatric Hematology Oncology 35 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00890500
Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.
Not yet reported Fate Therapeutics 12 participants Est. completion 2013-10 2 sitesOther conditions: Hematologic Malignancies, Allogeneic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT00894049
A Study Comparing Non Myeloablative (Flu-TBI) and Reduced Intensity (FLU-BU-ATG) Conditioning in Allogenic Transplantation
Not yet reported Institut Paoli-Calmettes 148 participants Est. completion 2013-02 5 sites Stand-aloneOther conditions: Allograft, Allogeneic Cell Transplantaion, Hematological Malignancy, Solid TumorView official trial listing → -
Completed NCT NCT00897260
Umbilical Cord Blood Transplantation As Treatment Of Adult Patients With Hematologic Disorders
Not yet reported University of British Columbia 27 participants Est. completion 2013-01-09 1 site Stand-aloneOther conditions: Hematological Malignancy, Bone Marrow Failure SyndromeView official trial listing → -
Terminated NCT NCT00899431
Nonmyeloablative Stem Cell Transplantation for Chronic Lymphocytic Leukemia (CLL)
Not yet reported M.D. Anderson Cancer Center 39 participants Est. completion 2018-10-07 1 siteOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT00902044
Her2 Chimeric Antigen Receptor Expressing T Cells in Advanced Sarcoma
Not yet reported Baylor College of Medicine 36 participants Est. completion 2032-07 2 sites Stand-aloneOther conditions: SarcomaView official trial listing → -
Status unknown NCT NCT00907036
Fludarabine Phosphate, Melphalan, and Alemtuzumab Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed Hodgkin Lymphoma
Not yet reported Cancer Research UK 49 participantsOther conditions: LymphomaView official trial listing → -
Completed NCT NCT00909168
Induction, Consolidation and Intensification Therapy for Patients Younger Than 66 Years With Previously Untreated CD33 Positive Acute Myeloid Leukemia (AML)
Not yet reported, Not yet reported University Hospital, Udine, Italy 130 participants Est. completion 2013-03 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT00909948
Intentional Rejection of the Donor Graft Using Recipient Leukocyte Infusion(s) Following Nonmyeloablative Allogeneic Stem Cell Transplant
Not yet reported Massachusetts General Hospital 7 participants Est. completion 2012-08 1 siteOther conditions: Non Hodgkin's Lymphoma, Hodgkin Disease, Multiple MyelomaView official trial listing → -
Completed NCT NCT00910650
Study of Gene Modified Immune Cells in Patients With Advanced Melanoma
Not yet reported Jonsson Comprehensive Cancer Center 14 participants Est. completion 2019-05-30 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT00912223
Blood Stem Cell Transplant With Low Dose Chemotherapy for Relapsed Follicular Non-Hodgkin's Lymphoma (BMT CTN 0701)
Not yet reported Medical College of Wisconsin 65 participants Est. completion 2016-08 21 sites Stand-aloneOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Completed NCT NCT00914849
Intravenous (IV) AMD3100 for Mobilization and Matched Related Transplant for Advanced Hematological Malignancies
Not yet reported Washington University School of Medicine 68 participants Est. completion 2012-02 1 site Stand-aloneOther conditions: Hematologic NeoplasmsView official trial listing → -
Terminated NCT NCT00914940
Selective Depletion of CD45RA+T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD
Not yet reported Fred Hutchinson Cancer Center 41 participants Est. completion 2020-05-26 2 sites Stand-aloneOther conditions: Graft Versus Host Disease, Leukemia, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT00915811
Pilot Study of Reduced Intensity Haematopoietic Stem Cell Transplantation in Patients With Poor Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukaemia (AML) Utilising Conditioning With Fludarabine, Busulphan and Thymoglobulin
Not yet reported King's College Hospital NHS Trust 20 participants Est. completion 2011-06 1 site Stand-aloneOther conditions: Myelodysplastic Syndromes, Leukemia, Myeloid, AcuteView official trial listing → -
Terminated NCT NCT00916045
Pilot Study of Unrelated Cord Blood Transplantation
Not yet reported King's College Hospital NHS Trust 40 participants Est. completion 2012-03 1 siteOther conditions: Leukemia, Myeloid, Acute, Myelodysplastic Syndromes, Leukemia, Lymphoblastic, Acute, Lymphoma, Non-Hodgkin, Hodgkin Disease, Chronic Lymphocytic LeukemiaView official trial listing → -
Withdrawn NCT NCT00918450
Study Assessing the Safety and Efficacy of ABT-263 in Subjects With B-cell Chronic Lymphocytic Leukemia (CLL) Who Have Failed at Least One Prior Fludarabine-containing Regimen
Not yet reported Abbott 150 participantsOther conditions: B-cell Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00918723
Vorinostat, Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2016-10 2 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Stage I Chronic Lymphocytic Leukemia, Stage I Small Lymphocytic Lymphoma, Stage II Chronic Lymphocytic Leukemia, Stage II Small Lymphocytic Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage III Small Lymphocytic Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT00919503
Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders
Not yet reported Fred Hutchinson Cancer Center 98 participants Est. completion 2020-06-10 6 sites Stand-aloneOther conditions: Non-Neoplastic Hematologic and Lymphocytic DisorderView official trial listing → -
Completed NCT NCT00923195
Radiation, Chemotherapy, Vaccine and Anti-MART-1 and Anti-gp100 Cells for Patients With Metastatic Melanoma
Not yet reported National Cancer Institute (NCI) 4 participants Est. completion 2011-08 1 site Stand-aloneOther conditions: Melanoma, Skin CancerView official trial listing → -
Completed NCT NCT00923351
Therapy to Treat Ewing's Sarcoma, Rhabdomyosarcoma or Neuroblastoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 44 participants Est. completion 2018-05-15 1 site Stand-aloneObstructive sleep apnea Other conditions: Neuroblastoma, Sarcoma, Neuroectodermal Tumors, Primitive, PeripheralView official trial listing → -
Completed NCT NCT00923364
Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for MonoMAC
Not yet reported National Cancer Institute (NCI) 19 participants Est. completion 2017-02-26 1 site Stand-aloneOther conditions: MDS, Immunodeficiency, GATA2View official trial listing → -
Terminated NCT NCT00923390
Phase 1/2 Study of Metastatic Renal Cancer Using T-Cells Transduced With a T-Cell Receptor Which Recognizes TRAIL Bound to the DR4 Receptor
Not yet reported National Cancer Institute (NCI) 5 participants Est. completion 2012-08-24 1 siteOther conditions: Renal Cancer, Kidney CancerView official trial listing → -
Terminated NCT NCT00924001
Chemotherapy Followed by Infusion of DMF5 Cells to Treat Metastatic Melanoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 1 participants Est. completion 2010-10 1 site Stand-aloneOther conditions: Melanoma, Malignant Melanoma, Melanoma, ExperimentalView official trial listing → -
Completed NCT NCT00924170
Phase II Trial of LMB-2, Fludarabine and Cyclophosphamide for Adult T-Cell Leukemia
Not yet reported, Not yet reported National Cancer Institute (NCI) 18 participants Est. completion 2021-05-05 1 site Stand-aloneOther conditions: Adult T-Cell Leukemia (ATL)View official trial listing → -
Terminated NCT NCT00924287
Gene Therapy Using Anti-Her-2 Cells to Treat Metastatic Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 1 participants Est. completion 2010-12 1 site Stand-aloneOther conditions: Metastatic CancerView official trial listing → -
Completed NCT NCT00924326
CAR T Cell Receptor Immunotherapy for Patients With B-cell Lymphoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 43 participants Est. completion 2021-11-17 1 site Stand-aloneOther conditions: Primary Mediastinal B-cell Lymphoma, Diffuse, Large B-cell Lymphoma, Diffuse Large B-Cell Lymphoma Transformed From Follicular Lymphoma, Mantle CellView official trial listing → -
Completed NCT NCT00925821
Lenalidomide-Adriamycin-Dexamethasone (RAD) Induction Followed by Stem Cell Transplant in Newly Diagnosed Multiple Myeloma
Not yet reported Wuerzburg University Hospital 146 participants 12 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00925873
GOELAMS SA4 Study: the Role of Fludarabine in the Treatment of Acute Myeloid Leukemia in the Elderly
Not yet reported French Innovative Leukemia Organisation 303 participants Est. completion 2004-11 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00931645
Autologous Stem Cell Transplantation in Chronic Lymphocytic Leukemia
Not yet reported University Hospital, Caen 241 participants Est. completion 2008-12 1 siteOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT00933335
Study of Safety and Efficacy of a Sequential Regimen Consisting of Three Cycles of Fludarabine Followed by Tositumomab and Iodine I 131 Tositumomab
Not yet reported GlaxoSmithKline 38 participants Est. completion 2010-08 Stand-aloneOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Withdrawn NCT NCT00937300
T-cell Based Immunotherapy for Head and Neck Cancer
Not yet reported Inge Marie Svane Est. completion 2011-06 1 siteOther conditions: Squamous Cell Carcinoma, Head and Neck CancerView official trial listing → -
Completed NCT NCT00937625
T-cell Based Immunotherapy for of Melanoma
Not yet reported, Not yet reported Inge Marie Svane 31 participants Est. completion 2015-01 1 siteOther conditions: MelanomaView official trial listing → -
Terminated NCT NCT00941928
Haploidentical Natural Killer (NK) Cells With Epratuzumab for Relapsed Acute Lymphoblastic Leukemia (ALL)
Not yet reported M.D. Anderson Cancer Center 2 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: Leukemia, Pediatric CancerView official trial listing → -
Terminated NCT NCT00943293
Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies
Not yet reported University of Chicago 1 participants Est. completion 2012-01 1 site Stand-aloneOther conditions: Preleukemia, Myeloproliferative Disorders, Lymphoma, Myeloma, Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT00943319
Busulfan-fludarabine Conditioning and T-cell Depleted Allogeneic Stem Cell Transplantation for Patients With Advanced Hematologic Malignancies
Not yet reported, Not yet reported University of Chicago 50 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, MyelomaView official trial listing → -
Completed NCT NCT00943800
Combined Haploidentical-Cord Blood Transplantation for Adults and Children
Not yet reported University of Chicago 87 participants Est. completion 2018-09 1 site Stand-aloneOther conditions: Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, LymphomaView official trial listing → -
Terminated NCT NCT00946023
Optimized Donor Selection, Nonmyeloablative BMT for B-cell Lymphomas With Post-transplantation Cy and Rituximab
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 135 participants Est. completion 2013-07-17 1 site Stand-aloneOther conditions: Lymphoma, B-cell Lymphoma, Non Hodgkin Lymphoma, Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT00946374
Prospective Trial on Immunochemotherapy Plus Autologous Stem Cell Transplantation (SCT) and Allogenic SCT in Primary Mantle-Cell-Lymphoma
Not yet reported Heidelberg University 20 participants Est. completion 2011-06 1 siteOther conditions: Mantle-Cell LymphomaView official trial listing → -
Terminated NCT NCT00947388
Bendamustine Plus Alemtuzumab for Refractory Chronic Lymphocytic Leukemia (CLL)
Not yet reported Case Comprehensive Cancer Center 9 participants Est. completion 2013-03 2 sitesOther conditions: Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Stage III Chronic Lymphocytic Leukemia, Stage III Small Lymphocytic Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT00948922
Melphalan+Bortezomib as a Conditioning Regimen for Autologous and Allogeneic Stem Cell Transplants in Multiple Myeloma
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 124 participants Est. completion 2019-05-14 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT00950846
Umbilical Cord Blood Transplant for Congenital Pediatric Disorders
Not yet reported Baylor College of Medicine 40 participants Est. completion 2021-02-04 1 site Stand-aloneOther conditions: Congenital Pediatric DisordersView official trial listing → -
Status unknown NCT NCT00958854
Fludarabine, Cyclophosphamide, and Thalidomide in Treating Patients With Angioimmunoblastic T-Cell Lymphoma
Not yet reported Cancer Research UK 37 participants 1 siteOther conditions: LymphomaView official trial listing → -
Status unknown NCT NCT00959231
Donor Umbilical Cord Blood Transplant After Cyclophosphamide, Fludarabine Phosphate, and Total-Body Irradiation in Treating Patients With Hematologic Disease
Not yet reported Cancer Research UK 60 participants 6 sitesOther conditions: Hematopoietic/Lymphoid CancerView official trial listing → -
Terminated NCT NCT00961142
Haploidentical Stem Cell Transplantation With CD3/CD19 Depletion and Reduced Intensity Conditioning in Patients With Acute Leukemia
Not yet reported University Hospital Tuebingen 23 participants Est. completion 2015-12-30 8 sitesOther conditions: Acute Myeloid Leukemia, Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT00963872
Donor Umbilical Cord Blood Transplant After Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Cancer
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 31 participants Est. completion 2013-08 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT00966810
Allogeneic Stem Cell Transplantation in CML With Partial T Cell Depletion
Not yet reported, Not yet reported Rambam Health Care Campus 40 participants Est. completion 2011-01 1 site Stand-aloneOther conditions: Philadelphia Chromosome-positive Chronic Myelocytic LeukemiaView official trial listing → -
Completed NCT NCT00968162
Sickle Cell Disease Conditioning for Bone Marrow Transplant
Not yet reported Emory University 8 participants Est. completion 2016-01-11 10 sites Stand-aloneOther conditions: Bone Marrow Transplantation, Sickle Cell DiseaseView official trial listing → -
Withdrawn NCT NCT00968461
Study of Phenethyl Isothiocyanate in Lymphoproliferative Disorders
Not yet reported M.D. Anderson Cancer CenterOther conditions: Leukemia, Lymphoproliferative DisordersView official trial listing → -
Withdrawn NCT NCT00972101
Infusion of Expanded Cord Blood T Cells
Not yet reported M.D. Anderson Cancer Center Est. completion 2011-09 Stand-aloneOther conditions: Stem Cell Transplantation, Leukemia, Lymphoma, Pediatric DisordersView official trial listing → -
Completed NCT NCT00987480
Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine
Not yet reported Memorial Sloan Kettering Cancer Center 45 participants Est. completion 2017-07-10 6 sites Stand-aloneOther conditions: Aplastic Anemia, Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT00988013
Intensity Modulated Total Marrow Irradiation (IM-TMI) for Advanced Hematologic Malignancies
Not yet reported University of Illinois at Chicago 14 participants Est. completion 2016-02 1 siteOther conditions: Acute Myeloid Leukemia, Lymphoblastic Leukemia, Acute Leukemia, Non Hodgkins Lymphoma, Chronic Myeloid LeukemiaView official trial listing → -
Completed NCT NCT00988715
Donor Peripheral Blood Stem Cell Transplant and Pretargeted Radioimmunotherapy in Treating Patients With High-Risk Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome
Not yet reported Fred Hutchinson Cancer Center 17 participants 1 site Stand-aloneOther conditions: Chronic Myelomonocytic Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndrome, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Refractory Anemia With Excess Blasts, Refractory Cytopenia With Multilineage Dysplasia, Refractory Cytopenia With Multilineage Dysplasia and Ringed Sideroblasts, Secondary Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT00990496
A Study Using Allogenic-Cytomegalovirus (CMV) Specific Cells for Glioblastoma Multiforme (GBM)
Not yet reported Milton S. Hershey Medical Center 25 participants Est. completion 2010-10-28 Stand-aloneOther conditions: Glioblastoma MultiformeView official trial listing → -
Completed NCT NCT00997529
Mini Allo Stem Cell Transplantation for the Treatment of Solid Tumors
Not yet reported Beth Israel Deaconess Medical Center 14 participants Est. completion 2010-06 1 site Stand-aloneOther conditions: Metastatic Solid TumorView official trial listing → -
Status unknown NCT NCT00998270
Autologous Bone Marrow Transplantation (BMT) Compared With Allogeneic BMT in Multiple Myeloma
Not yet reported, Not yet reported Tehran University of Medical Sciences 185 participants Est. completion 2017-10 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT01005576
Reduced Intensity Transplant Conditioning Regimen for Severe Thalassemia
Not yet reported Washington University School of Medicine 21 participants Est. completion 2014-07 18 sites Stand-aloneOther conditions: Severe ThalassemiaView official trial listing → -
Completed NCT NCT01005745
Lymphodepletion Plus Adoptive Cell Transfer With High Dose IL-2 in Patients With Metastatic Melanoma
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 19 participants Est. completion 2025-08-18 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT01008462
Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia
Not yet reported Fred Hutchinson Cancer Center 16 participants Est. completion 2018-06-30 2 sites Stand-aloneOther conditions: B-Cell Prolymphocytic Leukemia, Hypodiploidy, Loss of Chromosome 17p, Plasma Cell Leukemia, Progression of Multiple Myeloma or Plasma Cell Leukemia, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Non-Hodgkin Lymphoma, Recurrent Childhood Hodgkin Lymphoma, Recurrent Childhood Non-Hodgkin Lymphoma, Recurrent Chronic Lymphocytic Leukemia, Recurrent Plasma Cell Myeloma, Recurrent Small Lymphocytic Lymphoma, Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Non-Hodgkin Lymphoma, Refractory Plasma Cell Myeloma, Refractory Small Lymphocytic Lymphoma, t(14;16), t(4;14), T-Cell Prolymphocytic Leukemia, Waldenstrom MacroglobulinemiaView official trial listing → -
Completed NCT NCT01010217
Mismatched Transplantation Using High-dose Post-transplant Cyclophosphamide
Not yet reported M.D. Anderson Cancer Center 176 participants Est. completion 2017-10-05 1 site Stand-aloneOther conditions: Blood Stem Cell Transplant Failure, Leukemia, Hematologic MalignanciesView official trial listing → -
Completed NCT NCT01013441
CD3/CD28 Bead Activated T-Cells Following Chemo-Immunotherapy in Patients With Chronic Lymphocytic Leukemia
Not yet reported University of Pennsylvania 20 participants Est. completion 2018-12 2 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT01019317
Fludarabine and Cytarabine in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)
Not yet reported M.D. Anderson Cancer Center 151 participants Est. completion 2012-09 1 site Stand-aloneOther conditions: Leukemia, AML, MDS, CMLView official trial listing → -
Completed NCT NCT01019876
Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases
Not yet reported, Not yet reported Columbia University 38 participants Est. completion 2021-09-07 1 site Stand-aloneOther conditions: Bone Marrow Failure, Osteopetrosis, Fanconi Anemia, Severe Combined ImmunodeficiencyView official trial listing → -
Completed NCT NCT01020539
Allogeneic Stem Cell Transplantation Followed By Targeted Immune Therapy In Average Risk Leukemia
Not yet reported Columbia University 18 participants Est. completion 2020-12 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Juvenile Myelomonocytic LeukemiaView official trial listing → -
Completed NCT NCT01020734
Donor Stem Cell Transplant or Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia in Remission
Not yet reported Asan Medical Center 263 participants Est. completion 2015-07 2 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT01027000
Donor Stem Cell Transplant in Treating Patients With High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported Alliance for Clinical Trials in Oncology 68 participants Est. completion 2023-04 25 sites Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT01028716
Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
Not yet reported Fred Hutchinson Cancer Center 46 participants Est. completion 2021-10-07 1 site Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Erythroid Leukemia in Remission, Acute Leukemia in Remission, Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukaemia With Prior Myelodysplastic Syndrome, Acute Myeloid Leukemia in Remission, Acute Myeloid Leukemia With FLT3/ITD Mutation, Acute Myeloid Leukemia With Inv(3)(Q21Q26.2); RPN1-EVI1, Acute Myeloid Leukemia With Multilineage Dysplasia, Acute Myeloid Leukemia With t(6;9), Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Complete Remission, B Acute Lymphoblastic Leukemia With T(1;19)(Q23;P13.3); E2A-PBX1 (TCF3-PBX1), Ph+ ALL, Burkitt Lymphoma, Childhood Acute Lymphoblastic Leukemia in Complete Remission, DS Stage II Plasma Cell Myeloma, DS Stage III Plasma Cell Myeloma, Myelodysplastic Syndrome, Recurrent Anaplastic Large Cell Lymphoma, Blasts Under 5 Percent of Bone Marrow Nucleated Cells, Recurrent Follicular Lymphoma, Recurrent Hodgkin Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma, Secondary Acute Myeloid Leukemia, T Lymphoblastic Lymphoma, Hematopoietic Cell Transplant RecipientView official trial listing → -
Terminated NCT NCT01037764
Donor-specific Allogeneic Hematopoietic Cell Transplantation for Acute Lymphoblastic Leukemia (ALL)
Not yet reported Asan Medical Center 100 participants Est. completion 2016-12 2 sites Stand-aloneOther conditions: Acute Lymphoid LeukemiaView official trial listing → -
Terminated NCT NCT01044745
Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer
Not yet reported University of Nebraska 20 participants Est. completion 2017-10-10 1 site Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Blastic Phase Chronic Myelogenous Leukemia, Contiguous Stage II Adult Burkitt Lymphoma, Contiguous Stage II Adult Diffuse Large Cell Lymphoma, Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Contiguous Stage II Adult Lymphoblastic Lymphoma, Contiguous Stage II Grade 1 Follicular Lymphoma, Contiguous Stage II Grade 2 Follicular Lymphoma, Contiguous Stage II Grade 3 Follicular Lymphoma, Contiguous Stage II Mantle Cell Lymphoma, Contiguous Stage II Marginal Zone Lymphoma, Contiguous Stage II Small Lymphocytic Lymphoma, de Novo Myelodysplastic Syndromes, Graft Versus Host Disease, Nodal Marginal Zone B-cell Lymphoma, Noncontiguous Stage II Adult Burkitt Lymphoma, Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma, Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma, Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma, Noncontiguous Stage II Adult Lymphoblastic Lymphoma, Noncontiguous Stage II Grade 1 Follicular Lymphoma, Noncontiguous Stage II Grade 2 Follicular Lymphoma, Noncontiguous Stage II Grade 3 Follicular Lymphoma, Noncontiguous Stage II Mantle Cell Lymphoma, Noncontiguous Stage II Marginal Zone Lymphoma, Noncontiguous Stage II Small Lymphocytic Lymphoma, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic Syndromes, Splenic Marginal Zone Lymphoma, Stage I Adult Burkitt Lymphoma, Stage I Adult Diffuse Large Cell Lymphoma, Stage I Adult Diffuse Mixed Cell Lymphoma, Stage I Adult Diffuse Small Cleaved Cell Lymphoma, Stage I Adult Immunoblastic Large Cell Lymphoma, Stage I Adult Lymphoblastic Lymphoma, Stage I Adult T-cell Leukemia/Lymphoma, Stage I Chronic Lymphocytic Leukemia, Stage I Cutaneous T-cell Non-Hodgkin Lymphoma, Stage I Grade 1 Follicular Lymphoma, Stage I Grade 2 Follicular Lymphoma, Stage I Grade 3 Follicular Lymphoma, Stage I Mantle Cell Lymphoma, Stage I Marginal Zone Lymphoma, Stage I Mycosis Fungoides/Sezary Syndrome, Stage I Small Lymphocytic Lymphoma, Stage II Adult T-cell Leukemia/Lymphoma, Stage II Chronic Lymphocytic Leukemia, Stage II Cutaneous T-cell Non-Hodgkin Lymphoma, Stage II Mycosis Fungoides/Sezary Syndrome, Stage III Adult Burkitt Lymphoma, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Adult Diffuse Mixed Cell Lymphoma, Stage III Adult Diffuse Small Cleaved Cell Lymphoma, Stage III Adult Immunoblastic Large Cell Lymphoma, Stage III Adult Lymphoblastic Lymphoma, Stage III Adult T-cell Leukemia/Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage III Cutaneous T-cell Non-Hodgkin Lymphoma, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage III Marginal Zone Lymphoma, Stage III Mycosis Fungoides/Sezary Syndrome, Stage III Small Lymphocytic Lymphoma, Stage IV Adult Burkitt Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Adult Diffuse Mixed Cell Lymphoma, Stage IV Adult Diffuse Small Cleaved Cell Lymphoma, Stage IV Adult Immunoblastic Large Cell Lymphoma, Stage IV Adult Lymphoblastic Lymphoma, Stage IV Adult T-cell Leukemia/Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell Lymphoma, Stage IV Marginal Zone Lymphoma, Stage IV Mycosis Fungoides/Sezary Syndrome, Stage IV Small Lymphocytic Lymphoma, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid Leukemia, Waldenström MacroglobulinemiaView official trial listing → -
Terminated NCT NCT01045382
MSC and HSC Coinfusion in Mismatched Minitransplants
Not yet reported University of Liege 39 participants Est. completion 2021-08 10 sites Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Leukemia, Lymphoblastic, Acute, Leukemia, Myelocytic, Chronic, Myeloproliferative Disorders, Myelodysplastic Syndromes, Multiple Myeloma, Leukemia, Lymphocytic, Chronic, Hodgkin's Disease, Lymphoma, Non-HodgkinView official trial listing → -
Withdrawn NCT NCT01047072
Low-Dose Conditioning Followed by Donor Stem Cell Transplant in Treating Patients With Severe Systemic Sclerosis
Not yet reported Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium 1 site Stand-aloneOther conditions: Systemic SclerodermaView official trial listing → -
Completed NCT NCT01049854
CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant
Not yet reported New York Medical College 20 participants Est. completion 2018-08 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Bone Marrow Failure, Immunodeficiencies, Histiocytosis, Sickle Cell Disease, Beta Thalassemia, Inborn Errors of MetabolismView official trial listing → -
Terminated NCT NCT01050439
Unrelated Donor Transplant for Malignant and Non-Malignant Disorders
Not yet reported Columbia University 22 participants Est. completion 2011-04 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Bone Marrow Failure Syndromes, Immunodeficiencies, HistiocytosisView official trial listing → -
Terminated NCT NCT01050764
Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells
Not yet reported, Not yet reported Everett Meyer 10 participants Est. completion 2014-06 1 site Stand-aloneOther conditions: Leukemia, Acute, Chronic Myelogenous Leukemia (CML), Myelodysplastic Syndrome (MDS), Non-Hodgkin Lymphoma (NHL), Chronic Lymphocytic Leukemia (CLL), Acute Myelogenous Leukemia (AML), Acute Lymphoblastic Leukemia (ALL)View official trial listing → -
Completed NCT NCT01050855
Reduced Intensity Conditioning (RIC) Regimen for Patients With Non-malignant Disorders
Not yet reported Children's Hospital of Philadelphia 56 participants Est. completion 2025-06 1 site Stand-aloneOther conditions: Non Malignant Diseases, Immunodeficiencies, HemoglobinopathiesView official trial listing → -
Terminated NCT NCT01050946
Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit
Not yet reported Medical College of Wisconsin 1 participants Est. completion 2013-03Other conditions: Leukemia, Lymphocytic, Acute, Leukemia, Lymphocytic, Chronic, Leukemia, Myelocytic, Acute, Leukemia, Myeloid, Chronic, Lymphoma, Non-Hodgkin, Lymphoma, HodgkinsView official trial listing → -
Status unknown NCT NCT01051115
Dasatinib Combination for Chronic Lymphocytic Leukemia(CLL) With Refractory Disease
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 35 participants Est. completion 2016-01 4 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT01056614
Fludarabine Phosphate, Busulfan, and Anti-Thymocyte Globulin Followed By Donor Peripheral Blood Stem Cell Transplant, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Malignancies
Not yet reported Fred Hutchinson Cancer Center 23 participants Est. completion 2016-04 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Blastic Phase Chronic Myelogenous Leukemia, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Chronic Phase Chronic Myelogenous Leukemia, de Novo Myelodysplastic Syndromes, Hematopoietic/Lymphoid Cancer, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Relapsing Chronic Myelogenous LeukemiaView official trial listing → -
Completed NCT NCT01063660
Treosulfan Based Conditioning Acute Myeloid Leukaemia (AML)
Not yet reported medac GmbH 75 participants Est. completion 2007-07 1 siteOther conditions: Acute Myeloid LeukaemiaView official trial listing → -
Withdrawn NCT NCT01065545
The Role of Maintenance Oral Clofarabine in Older Adults With Acute Myeloid Leukemia
Not yet reported Northwestern UniversityOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT01067300
A Study Comparing Single Versus Double Umbilical Cord Blood Transplantation in the Young With Acute Leukemia Remission
Not yet reported Assistance Publique Hopitaux De Marseille 198 participants Est. completion 2016-01 1 siteOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT01068301
A Pediatric Study of a Plerixafor Containing Regimen In Second Allogeneic Stem Cell Transplantation
Not yet reported St. Jude Children's Research Hospital 12 participants Est. completion 2013-10 1 siteOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Myelodysplastic Syndrome, Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT01071239
Hematopoietic Stem Cell Transplant for Fanconi Anemia
Not yet reported Medical College of Wisconsin 1 participants Est. completion 2016-08-30 1 site Stand-aloneOther conditions: Fanconi AnemiaView official trial listing → -
Status unknown NCT NCT01079013
Treosulfan-based Conditioning for Allogeneic Stem-cell Transplantation (SCT) in Lymphoid Malignancies
Not yet reported Sheba Medical Center 40 participants Est. completion 2018-04 1 siteOther conditions: Non Hodgkin Lymphoma, Hodgkin LymphomaView official trial listing → -
Completed NCT NCT01082939
Cyclophosphamide, Fludarabine, Alemtuzumab, and Rituximab (CFAR) for Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)
Not yet reported M.D. Anderson Cancer Center 80 participants Est. completion 2011-01 1 site Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT01085617
Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia
University College, London Est. completion 2025-02-24 Stand-aloneOther conditions: Leukemia, Mucositis, Oral ComplicationsView official trial listing → -
Status unknown NCT NCT01087398
Hematopoietic Stem Cell Transplantation for Malignant Infantile Osteopetrosis
Not yet reported, Not yet reported Tehran University of Medical Sciences 10 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: OsteopetrosisView official trial listing → -
Completed NCT NCT01088048
Study to Investigate Idelalisib in Combination With Chemotherapeutic Agents, Immunomodulatory Agents and Anti-CD20 Monoclonal Antibody (mAb) in Participants With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma, Mantle Cell Lymphoma or Chronic Lymphocytic Leukemia
Not yet reported Gilead Sciences 241 participants Est. completion 2015-04-28 11 sites Stand-aloneOther conditions: Indolent Non-Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT01088724
Fludarabine, Cyclophosphamide, Doxorubicin and Rituximab for the Treatment of Post-transplant Lymphoproliferative Disease (PTLD)
Not yet reported A.O. Ospedale Papa Giovanni XXIII 4 participants Est. completion 2010-03 1 site Stand-aloneOther conditions: Post-transplant Lymphoproliferative Disease (PTLD), Non BurkittView official trial listing → -
Completed NCT NCT01096992
Fludarabine, Bendamustine, and Rituximab (FBR) for Relapsed Chronic Lymphocytic Leukemia (CLL)
Not yet reported, Not yet reported M.D. Anderson Cancer Center 51 participants Est. completion 2017-03-31 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT01105273
Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Aplastic Anemia
Not yet reported, Not yet reported Asan Medical Center 12 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Completed NCT NCT01105650
Allogeneic Natural Killer (NK) Cells for Ovarian, Fallopian Tube, Peritoneal and Metastatic Breast Cancer
Not yet reported Masonic Cancer Center, University of Minnesota 13 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, Breast CancerView official trial listing → -
Terminated NCT NCT01106950
Haploidentical Natural Killer Cells to Treat Refractory or Relapsed Acute Myelogenous Leukemia (AML)
Not yet reported Masonic Cancer Center, University of Minnesota 15 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Leukemia, Myelogenous, AcuteView official trial listing → -
Completed NCT NCT01110031
Ofatumumab Cardiac Repolarization (QTc) Study in Fludarabine-Refractory Chronic Lymphocytic Leukemia Subjects
Not yet reported GlaxoSmithKline 12 participants Est. completion 2012-06-26 4 sitesOther conditions: Leukaemia, Lymphocytic, ChronicView official trial listing → -
Completed NCT NCT01113632
Ofatumumab for Patients With Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported SCRI Development Innovations, LLC 77 participants Est. completion 2016-08 13 sitesOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT01117441
International Collaborative Treatment Protocol For Children And Adolescents With Acute Lymphoblastic Leukemia
Not yet reported University Hospital Schleswig-Holstein 6136 participants Est. completion 2021-12-31 139 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT01118013
Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Malignancies or Secondary Myelodysplasia Previously Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant
Not yet reported Alliance for Clinical Trials in Oncology 6 participants Est. completion 2013-08 10 sites Stand-aloneOther conditions: Leukemia, Lymphoma, Lymphoproliferative Disorder, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative NeoplasmsView official trial listing → -
Completed NCT NCT01118091
Prospective Randomized Comparative Study of Cell Transfer Therapy Using CD8+-Enriched Short-Term Cultured Anti-Tumor Autologous Lymphocytes Following a Non-Myeloablative Lymphocyte Depleting Chemotherapy Regimen Compared to High-Dose Aldesleukin in M...
Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2012-04 1 site Stand-aloneOther conditions: Skin Cancer, Melanoma, Metastatic MelanomaView official trial listing → -
Completed NCT NCT01119066
HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies
Not yet reported Memorial Sloan Kettering Cancer Center 422 participants Est. completion 2021-03-30 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Multiple MyelomaView official trial listing → -
Completed NCT NCT01121029
Hematopoietic Stem Cell Transplantation in Type 1 Diabetes Mellitus
Not yet reported, Not yet reported Dra. Olga Graciela Cantu Rodriguez 15 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT01124526
Efficacy Response Duration and Toxicity of Rituximab, Fludarabine, and Cyclophosphamide (RFC) as 1st Line Treatment and Rituximab (R) in Maintenance Treatment in Follicular Non Hodgkin (FNH) Lymphoma
Not yet reported Asociacion Espanola de Hematologia y Hemoterapia 75 participants Est. completion 2008-07 20 sites Stand-aloneOther conditions: Non Hodgkin LymphomaView official trial listing → -
Withdrawn NCT NCT01129323
Reduced-Intensity Preparative Regimen for Allogeneic Stem Cell Transplantation in Patients With Severe Aplastic Anemia
Not yet reported City of Hope Medical Center Stand-aloneOther conditions: Severe Aplastic AnemiaView official trial listing → -
Completed NCT NCT01131169
Busulfan, Melphalan, Fludarabine and T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Followed by Post Transplantation Donor Lymphocyte Infusions
Not yet reported Memorial Sloan Kettering Cancer Center 66 participants Est. completion 2020-05-15 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Terminated NCT NCT01135329
Reduced-intensity, Related-donor Bone Marrow Transplantation Followed by High-dose Cyclophosphamide for Hematologic Cancers
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 15 participants Est. completion 2012-05 1 site Stand-aloneOther conditions: Lymphoma, Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01145209
Ofatumumab-based Induction Chemoimmunotherapy in Previously Untreated Patients With CLL/SLL
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 32 participants Est. completion 2023-09-15 1 site Stand-aloneOther conditions: Small Lymphocytic Lymphoma, CLL (Chronic Lymphocytic Leukemia)View official trial listing → -
Completed NCT NCT01145469
Biomarkers in DNA Samples From Patients With Chronic Lymphocytic Leukemia Previously Treated With Fludarabine-Based Therapy
Eastern Cooperative Oncology Group 225 participants Est. completion 2010-08-01Other conditions: LeukemiaView official trial listing → -
Status unknown NCT NCT01145976
Comparison of Cy-Atg vs Flu-Atg for the Conditioning Therapy in Allo-HCT for Adult Aplastic Anemia
Not yet reported Cooperative Study Group A for Hematology 98 participants Est. completion 2016-02 1 site Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Completed NCT NCT01153971
A Study of Induction and Maintenance Treatment With MabThera (Rituximab) in Patients With Indolent B-Cell Nonfollicular Lymphomas
Not yet reported Hoffmann-La Roche 47 participants Est. completion 2010-09-24 15 sitesOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Status unknown NCT NCT01156350
Haplo-identical Hematopoietic Stem Cell Transplantation Following Reduced-intensity Conditioning in Children With Neuroblastoma
Not yet reported University Hospital, Clermont-Ferrand 10 participants Est. completion 2014-09 1 siteOther conditions: NeuroblastomaView official trial listing → -
Terminated NCT NCT01158885
Clofarabine With Cytarabine for Patients With Minimal Residual Disease Positive Leukemia
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 2 participants Est. completion 2012-10-24 2 sitesOther conditions: Minimal Residual Disease, Leukemia, Lymphoblastic, Acute, Leukemia, Myelogenous, AcuteView official trial listing → -
Withdrawn NCT NCT01163201
T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignancies
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota Est. completion 2015-01 1 site Stand-aloneOther conditions: Hematologic Malignancy, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia in Blast Crisis, Anemia, Refractory, With Excess of Blasts, Chronic Myeloproliferative Disease, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone B-cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Lymphoma, Large Cell Non-Hodgkin's Lymphoma, Lymphoblastic Lymphoma, Burkitt's Lymphoma, High Grade Non-Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT01163357
Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma
Not yet reported City of Hope Medical Center 18 participants Est. completion 2024-05-20 1 site Stand-aloneOther conditions: Autologous Hematopoietic Stem Cell Transplant Recipient, Loss of Chromosome 17p, Plasma Cell Leukemia, Recurrent Plasma Cell Myeloma, Refractory Plasma Cell MyelomaView official trial listing → -
Completed NCT NCT01168219
Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia
Not yet reported National Cancer Institute (NCI) 68 participants Est. completion 2020-02-01 17 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Adult Acute Megakaryoblastic Leukemia, Adult Acute Monoblastic Leukemia, Adult Acute Monocytic Leukemia, Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11, Adult Acute Myeloid Leukemia With Maturation, Adult Acute Myeloid Leukemia With Minimal Differentiation, Adult Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11, Adult Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1, Adult Acute Myeloid Leukemia With t(9;11)(p21.3;q23.3); MLLT3-MLL, Adult Acute Myeloid Leukemia Without Maturation, Adult Acute Myelomonocytic Leukemia, Adult Erythroleukemia, Adult Pure Erythroid Leukemia, Alkylating Agent-Related Acute Myeloid Leukemia, de Novo Myelodysplastic Syndrome, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts, Recurrent Adult Acute Myeloid Leukemia, Secondary Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT01173679
Dasatinib With Fludarabine and Rituximab in Relapsed and Refractory CLL and SLL
Not yet reported Massachusetts General Hospital 10 participants Est. completion 2015-01 3 sitesOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT01175785
Infusion of Off-the-Shelf Expanded Cord Blood Cells to Augment Cord Blood Transplant in Patients With Hematologic Malignancies
Not yet reported Nohla Therapeutics, Inc. 15 participants Est. completion 2014-08 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes, Chronic Phase Chronic Myelogenous Leukemia, de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Refractory Anemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Excess Blasts in Transformation, Relapsing Chronic Myelogenous Leukemia, Secondary Myelodysplastic SyndromesView official trial listing → -
Active, not recruiting NCT NCT01176006
Pilot Study of Reduced-Intensity Hematopoietic Stem Cell Transplant of DOCK8 Deficiency
Not yet reported National Cancer Institute (NCI) 70 participants Est. completion 2028-10-31 1 siteOther conditions: DOCK8 DeficiencyView official trial listing → -
Completed NCT NCT01181258
Penostatin, Rituximab and Ontak and Allogeneic Natural Killer (NK) Cells for Refractory Lymphoid Malignancies
Not yet reported Masonic Cancer Center, University of Minnesota 16 participants Est. completion 2016-07 1 site Stand-aloneOther conditions: Non-Hodgkin Lymphoma, Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT01181271
Tandem Auto-Allo Transplant for Lymphoma
Not yet reported Massachusetts General Hospital 42 participants Est. completion 2016-02 2 sites Stand-aloneOther conditions: Diffuse, Large B-Cell, Lymphoma, Lymphoma, Low-Grade, T-Cell Lymphoma, Mantle-Cell Lymphoma, Hodgkin's Lymphoma, Chronic Lymphocytic Leukemia, Lymphoma, Small LymphocyticView official trial listing → -
Terminated NCT NCT01186458
Fludarabine, Velcade and Rituximab for Relapsed or Refractory Follicular Non-Hodgkin Lymphoma
Not yet reported Hoosier Cancer Research Network 4 participants Est. completion 2013-10 11 sites Stand-aloneOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Completed NCT NCT01187017
A Pilot Study of Fludarabine Plus Cyclophosphamide in Refractory Severe Aplastic Anemia
Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 1 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Aplastic Anemia, Neutropenia, Pancytopenia, Severe Aplastic AnemiaView official trial listing → -
Completed NCT NCT01191957
Busulfan (BU) Plus Fludarabine Vs Intravenous BU Plus Cyclophosphamide as Conditioning Regimens Prior Allogeneic Hematopoetic Stem Cells Transplant (HSCT) in AML
Not yet reported Gruppo Italiano Trapianto di Midollo Osseo 252 participants Est. completion 2014-10 26 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT01203020
Once Daily Targeted Intravenous (IV) Busulfex as Part of Reduced-toxicity Conditioning for Patients With Refractory Lymphomas Undergoing Allogeneic Transplantation
Not yet reported West Virginia University 22 participants Est. completion 2021-09-27 1 site Stand-aloneOther conditions: Hodgkin's Lymphoma, Non-Hodgkin's LymphomaView official trial listing → -
Terminated NCT NCT01203228
Dose-reduced Versus Standard Conditioning in MDS/sAML
Not yet reported European Society for Blood and Marrow Transplantation 129 participants Est. completion 2015-02 14 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, Secondary Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01203722
Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies
Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 87 participants Est. completion 2024-05-28 1 siteOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT01208896
Allogeneic Hematopoietic Stem Cell Transplantation After Reduced-intensity Conditioning for Relapsed Follicular Lymphoma
Not yet reported University Hospital, Bordeaux 32 participants Est. completion 2017-09-28 26 sites Stand-aloneOther conditions: Lymphoma, Follicular, Stem Cell TransplantationView official trial listing → -
Terminated NCT NCT01212887
Treated Blood Cells, Cyclophosphamide, Fludarabine Phosphate, and Aldesleukin in Treating Patients With Cancer
Not yet reported Cancer Research UK 14 participants Est. completion 2010-04 1 siteOther conditions: Breast Cancer, Colorectal Cancer, Gastric Cancer, Lung Cancer, Ovarian Cancer, Pancreatic Cancer, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Terminated NCT NCT01218867
CAR T Cell Receptor Immunotherapy Targeting VEGFR2 for Patients With Metastatic Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 24 participants Est. completion 2015-12-15 1 site Stand-aloneOther conditions: Metastatic Cancer, Metastatic Melanoma, Renal CancerView official trial listing → -
Status unknown NCT NCT01220544
Haploidentical Transplantation With Early Adoptive Transfer of CD56+CD3- NK Cells
Not yet reported, Not yet reported Charite University, Berlin, Germany 30 participants Est. completion 2011-10 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemias, Advanced Hematological Malignancies, Indication for Allogeneic Stem Cell Transplantation, no HLA-identical Donor AvailableView official trial listing → -
Completed NCT NCT01231412
Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant
Not yet reported Fred Hutchinson Cancer Center 174 participants Est. completion 2017-06-30 11 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Aggressive Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Diffuse Large B-Cell Lymphoma, Hematopoietic and Lymphoid Cell Neoplasm, Indolent Non-Hodgkin Lymphoma, Mantle Cell Lymphoma, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Plasma Cell Myeloma, Refractory Chronic Lymphocytic Leukemia, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Hodgkin Lymphoma, Small Lymphocytic Lymphoma, T-Cell Chronic Lymphocytic Leukemia, Waldenstrom MacroglobulinemiaView official trial listing → -
Terminated NCT NCT01236573
Cell Therapy for Metastatic Melanoma Using CD8 Enriched Tumor Infiltrating Lymphocytes
Not yet reported, Not yet reported National Institutes of Health Clinical Center (CC) 34 participants Est. completion 2015-03 1 site Stand-aloneOther conditions: Skin Cancer, Metastatic MelanomaView official trial listing → -
Status unknown NCT NCT01238328
Hematopoietic Stem Cell Transplantation for Mucopolysaccharidosis
Not yet reported, Not yet reported Tehran University of Medical Sciences 10 participants Est. completion 2012-12 1 site Stand-aloneOther conditions: MucopolysaccharidosisView official trial listing → -
Completed NCT NCT01244906
Post-transplant Cyclophosphamide and Sirolimus Following Reduced Intensity Conditioning (RIC) Transplant
Not yet reported Northside Hospital, Inc. 26 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Hematologic NeoplasmsView official trial listing → -
Completed NCT NCT01246557
Study Assessing Safety and Efficiency of the Lenalidomide and Dexamethasone Combination in Patients With Chronic Lymphatic Leukemia (CLL) Relapsing or Resistant to Treatment
Not yet reported, Not yet reported Hospital Universitari Vall d'Hebron Research Institute 20 participants Est. completion 2014-04 6 sitesOther conditions: Chronic Lymphatic LeukemiaView official trial listing → -
Completed NCT NCT01247493
Modified-FLAI Induction and Consolidation Chemotherapy in Elderly Patient With Acute Myeloid Leukemia (AML)
Not yet reported Seoul National University Hospital 108 participants Est. completion 2010-07 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT01247688
Umbilical Cord Blood Transplant for Children With Lymphoid Hematological Malignancies
Not yet reported Baylor College of Medicine Est. completion 2013-12 Stand-aloneOther conditions: Lymphoid Hematological Malignancies, Umbilical Cord Blood TransplantView official trial listing → -
Completed NCT NCT01247701
Umbilical Cord Blood Transplant for Children With Myeloid Hematological Malignancies
Not yet reported Baylor College of Medicine 16 participants Est. completion 2019-10 1 site Stand-aloneOther conditions: Myeloid Hematological MalignanciesView official trial listing → -
Completed NCT NCT01251575
Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant
Not yet reported Fred Hutchinson Cancer Center 77 participants Est. completion 2019-02-11 5 sites Stand-aloneOther conditions: Adult Acute Lymphoblastic Leukemia, Adult Acute Myeloid Leukemia, Adult Diffuse Large B-Cell Lymphoma, Adult Myelodysplastic Syndrome, Adult Non-Hodgkin Lymphoma, Aggressive Non-Hodgkin Lymphoma, Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia, Childhood Diffuse Large B-Cell Lymphoma, Childhood Myelodysplastic Syndrome, Childhood Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia in Remission, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid Cell Neoplasm, Mantle Cell Lymphoma, Plasma Cell Myeloma, Prolymphocytic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, T-Cell Prolymphocytic Leukemia, Waldenstrom Macroglobulinemia, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT01255319
Cyclophosphamide, Fludarabine and Antithymocyte Globulin Conditioning in Myelodysplastic Syndrome (MDS)
Cooperative Study Group A for Hematology 15 participants Est. completion 2014-11 1 siteOther conditions: Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01256398
Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Not yet reported National Cancer Institute (NCI) 66 participants Est. completion 2021-11-15 101 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1View official trial listing → -
Completed NCT NCT01263704
A Study of MabThera/Rituxan (Rituximab) in Combination With Fludarabine And Cyclophosphamide as Primary Therapy in Elderly Patients With Chronic Lymphocytic Leukemia
Not yet reported Hoffmann-La Roche 42 participants Est. completion 2017-04-03 12 sites Stand-aloneOther conditions: Lymphocytic Leukemia, ChronicView official trial listing → -
Terminated NCT NCT01271010
A Study of Rituximab in Combination With Fludarabine and Cyclophosphamide in Participants With Chronic Lymphocytic Leukemia and Favorable Somatic Status
Not yet reported Hoffmann-La Roche 89 participants Est. completion 2016-05-04 10 sites Stand-aloneOther conditions: Lymphocytic Leukemia, ChronicView official trial listing → -
Terminated NCT NCT01271907
Drosophila-generated CTL
Not yet reported National Cancer Institute (NCI) 3 participants Est. completion 2011-12-08 1 site Stand-aloneOther conditions: Metastatic Cutaneous MelanomaView official trial listing → -
Status unknown NCT NCT01274195
Hematopoietic Stem Cell Transplantation With Targeted Busulfan and Fludarabine in Pediatric AML
Not yet reported Seoul National University Hospital 27 participants Est. completion 2013-12 1 siteOther conditions: Hematopoietic Stem Cell TransplantationView official trial listing → -
Terminated NCT NCT01279616
A Reduced Toxicity Allogeneic Unrelated Donor Stem Cell Transplantation (SCT) for Severe Sickle Cell Disease
Not yet reported Nationwide Children's Hospital 8 participants Est. completion 2015-01 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Terminated NCT NCT01283386
A Study to Compare Mabthera (Rituximab), Fludarabine and Cyclophosphamide to Mabthera and Chlorambucil in Participants With Chronic Lymphocytic Leukemia and Unfavorable Somatic Status
Not yet reported Hoffmann-La Roche 26 participants Est. completion 2016-03-16 8 sites Stand-aloneOther conditions: Lymphocytic Leukemia, ChronicView official trial listing → -
Completed NCT NCT01289457
Clofarabine, Idarubicin, and Cytarabine (CIA) Versus Fludarabine, Idarubicin, and Cytarabine (FLAI) in Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome
Not yet reported, Not yet reported M.D. Anderson Cancer Center 282 participants Est. completion 2017-06-28 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT01292135
Safety and Tolerability Study of PCI-32765 Combined With Fludarabine/Cyclophosphamide/Rituximab (FCR) and Bendamustine/Rituximab (BR) in Chronic Lymphocytic Leukemia (CLL)
Not yet reported Pharmacyclics LLC. 33 participants Est. completion 2013-05 6 sites Stand-aloneOther conditions: B-cell Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT01292603
A Study to Compare Subcutaneous Versus Intravenous MabThera (Rituximab) in Combination With Chemotherapy in Patients With Chronic Lymphocytic Leukemia
Not yet reported Hoffmann-La Roche 240 participants Est. completion 2017-11-17 84 sites Stand-aloneOther conditions: Lymphocytic Leukemia, ChronicView official trial listing → -
Completed NCT NCT01300247
A Study of Obinutuzumab (GA101; RO5072759) in Combination With Chemotherapy in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GALTON)
Not yet reported Genentech, Inc. 41 participants Est. completion 2015-12 18 sites Stand-aloneOther conditions: Lymphocytic Leukemia, ChronicView official trial listing → -
Completed NCT NCT01300572
Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS
Not yet reported Fred Hutchinson Cancer Center 16 participants Est. completion 2019-11-22 1 site Stand-aloneOther conditions: Chronic Myelomonocytic Leukemia, Previously Treated Myelodysplastic Syndrome, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Refractory Anemia With Excess Blasts, Secondary Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01303887
A Trial Looking at Rituximab and Chemotherapy as a Treatment for Follicular Lymphoma in Elderly Patients
Not yet reported University of Liverpool 680 participants Est. completion 2023-05-11 73 sites Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Completed NCT NCT01310179
Safety Study of Adenovirus/PNP Coupled With Fludarabine Phosphate to Treat Solid Tumors
Not yet reported PNP Therapeutics, Inc. 12 participants Est. completion 2014-07 2 sites Stand-aloneOther conditions: Head and Neck CancerView official trial listing → -
Terminated NCT NCT01312376
Autologous T-Cells Combined With Autologous OC-DC Vaccine in Ovarian Cancer
Not yet reported Abramson Cancer Center at Penn Medicine 18 participants Est. completion 2019-01 1 siteOther conditions: Ovarian Carcinoma, Fallopian Tube Cancer, Primary Peritoneal CancerView official trial listing → -
Completed NCT NCT01316549
Study of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation
University of California, San Francisco 67 participants Est. completion 2016-04-30 1 siteOther conditions: Hematologic Malignancies, Nonmalignant Diseases, Immunodeficiencies, Hemoglobinopathies, Genetic Inborn Errors of Metabolism, Fanconi Anemia, Thalassemia, Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT01319565
Prospective Randomized Study of Cell Transfer Therapy for Metastatic Melanoma Using Tumor Infiltrating Lymphocytes Plus IL-2 Following Non-Myeloablative Lymphocyte Depleting Chemo Regimen Alone or in Conjunction With 12Gy Total Body Irradiation (TBI...
Not yet reported National Cancer Institute (NCI) 102 participants Est. completion 2024-09-10 1 site Stand-aloneOther conditions: Metastatic Melanoma, Skin CancerView official trial listing → -
Status unknown NCT NCT01322776
Combination of Bortezomib, Fludarabine and Cyclophosphamide Treat Recurrent Mantle Cell Lymphoma
Not yet reported, Not yet reported Sun Yat-sen University 40 participants Est. completion 2013-10 1 site Stand-aloneOther conditions: Mantle Cell Lymphoma RecurrentView official trial listing → -
Completed NCT NCT01328496
Umbilical Cord Blood Transplantation In Patients With Hematologic Malignancies Using A Myeloablative Preparative Regimen
Not yet reported St. Jude Children's Research Hospital 14 participants Est. completion 2016-10-31 1 siteOther conditions: Hematologic Malignancies, Disorder Related to Transplantation, Hematopoietic MalignancyView official trial listing → -
Completed NCT NCT01336712
Total Body Irradiation/Fludarabine Based Ablative Haploidentical Transplant for Hematologic Diseases
Not yet reported Northside Hospital, Inc. 30 participants Est. completion 2015-07 1 site Stand-aloneOther conditions: Chronic Leukemia, Acute Leukemia, Hodgkin's Disease, Non-Hodgkin's Lymphoma, Myelodysplastic SyndromeView official trial listing → -
Status unknown NCT NCT01338675
Targeted Busulfan, Fludarabine Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Chronic Granulomatous Disease(CGD)
Not yet reported, Not yet reported Seoul National University Hospital 5 participants Est. completion 2013-12 1 siteOther conditions: Chronic Granulomatous DiseaseView official trial listing → -
Completed NCT NCT01338987
Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantation
Not yet reported National Cancer Institute (NCI) 76 participants Est. completion 2020-11-19 3 sites Stand-aloneOther conditions: Myelodysplastic Syndrome, Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia, Chronic Myelogenous Leukemia, Chronic Myelomonocytic LeukemiaView official trial listing → -
Terminated NCT NCT01339910
Reduced Intensity Regimen vs Myeloablative Regimen for Myeloid Leukemia or Myelodysplastic Syndrome (BMT CTN 0901)
Not yet reported Medical College of Wisconsin 272 participants Est. completion 2017-10-16 32 sites Stand-aloneOther conditions: Leukemia, Myelocytic, AcuteView official trial listing → -
Completed NCT NCT01342289
Shorter Course Tacrolimus After Nonmyeloablative, Related Donor BMT With High-dose Posttransplantation Cyclophosphamide
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 127 participants Est. completion 2018-03 1 site Stand-aloneOther conditions: Hodgkin's Lymphoma, Leukemia, Myelodysplastic Syndrome(MDS), Multiple Myeloma, Non Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT01343043
A Pilot Study of Genetically Engineered NY-ESO-1 Specific NY-ESO-1ᶜ²⁵⁹T in HLA-A2+ Patients With Synovial Sarcoma
Not yet reported GlaxoSmithKline 50 participants Est. completion 2019-06-18 8 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Completed NCT NCT01349101
A Research Study of Bone Marrow Transplantation From Unrelated or Partially Matched Related Donors
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 78 participants Est. completion 2022-12-07 1 site Stand-aloneOther conditions: Hematological MalignanciesView official trial listing → -
Terminated NCT NCT01350232
Treatment of Sickle Cell Anemia With Stem Cell Transplant
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 2 participants Est. completion 2011-08 1 site Stand-aloneOther conditions: Sickle Cell Anemia, Sickle Cell-hemoglobin C Disease, Sickle Cell-β0-thalassemiaView official trial listing → -
Terminated NCT NCT01350258
Bone Marrow Transplant Using a Reduced Intensity Regimen That is Given in Two Steps
Not yet reported, Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 8 participants Est. completion 2012-08 1 site Stand-aloneOther conditions: Hematologic Malignancies, Acute Leukemia, Myelodysplastic Syndromes (MDS) Other Than RA or RARS Subtypes, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Myeloma, Chronic Myelogenous (or Myeloid) Leukemia (CML) Resistant to STI TherapyView official trial listing → -
Terminated NCT NCT01359254
Cord Blood Transplantation for Patients With Cancer
Not yet reported University of Chicago 1 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: Hematological DiseaseView official trial listing → -
Completed NCT NCT01362452
Infusion of Allogeneic Umbilical Cord Blood-Derived Cluster of Differentiation Antigen 19 (CD19)-Specific T Cells
Not yet reported M.D. Anderson Cancer Center 5 participants Est. completion 2017-07-25 1 siteOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT01364363
Unrelated Donor Stem Cell Transplantation
Not yet reported Scripps Health 64 participants Est. completion 2015-07 1 siteOther conditions: Severe Aplastic Anemia, Paroxysmal Nocturnal Hemoglobinuria, Acute Myelogenous Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, Myeloproliferative Syndromes, Chronic Myelogenous Leukemia, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Multiple Myeloma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Large Granulocytic LeukemiaView official trial listing → -
Terminated NCT NCT01366612
Fludarabine and Busulfan vs. Fludarabine, Busulfan and Total Body Irradiation
Not yet reported Hackensack Meridian Health 53 participants Est. completion 2020-08-18 1 site Stand-aloneOther conditions: Myeloid Malignancies, Acute Myelogenous Leukemia, Chronic Myelogenous Leukemia, Myeloproliferative Disorders, Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT01369875
Modified Tumor Infiltrating Lymphocytes for Metastatic Melanoma
Not yet reported National Cancer Institute (NCI) 2 participants Est. completion 2012-02-14 1 site Stand-aloneOther conditions: Metastatic Melanoma, Skin CancerView official trial listing → -
Terminated NCT NCT01369888
Use of IL-15 After Chemotherapy and Lymphocyte Transfer in Metastatic Melanoma
Not yet reported, Not yet reported National Cancer Institute (NCI) 3 participants Est. completion 2014-05 1 site Stand-aloneOther conditions: Metastatic Melanoma, Skin CancerView official trial listing → -
Completed NCT NCT01370772
Intensified Rituimab Prephase Before FCR in Untreated B-CLL
Not yet reported French Innovative Leukemia Organisation 140 participants Est. completion 2016-03 2 sites Stand-aloneOther conditions: B-cell Chronic Lymphocytic Leukemia CLLView official trial listing → -
Completed NCT NCT01384513
A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 40 participants Est. completion 2022-11-16 1 site Stand-aloneObstructive sleep apnea Other conditions: Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Aplastic Anemia, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Myelodysplastic Syndromes, Chronic Eosinophilic Leukemia, Chronic Myelomonocytic Leukemia, Chronic Neutrophilic Leukemia, Essential Thrombocythemia, Juvenile Myelomonocytic Leukemia, Mastocytosis, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Polycythemia Vera, Previously Treated Myelodysplastic Syndromes, Primary Myelofibrosis, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Anemia, Refractory Anemia With Ringed Sideroblasts, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Secondary Myelodysplastic Syndromes, Splenic Marginal Zone Lymphoma, T-cell Large Granular Lymphocyte Leukemia, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT01385423
Haploidentical Donor Natural Killer Cell Infusion With IL-15 in Acute Myelogenous Leukemia (AML)
Not yet reported Masonic Cancer Center, University of Minnesota 26 participants Est. completion 2015-03 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01389427
Escalating Doses of Torisel in Combination With Three Chemotherapies Regimens: R-CHOP, R-FC or R-DHA for Patients With Relapsed/Refractory Mantle Cell Lymphoma (MCL).
Not yet reported, Not yet reported The Lymphoma Academic Research Organisation 41 participants Est. completion 2015-09 11 sites Stand-aloneOther conditions: Mantle Cell Lymphoma RefractoryView official trial listing → -
Completed NCT NCT01408563
Reduced Intensity Double Umbilical Cord Blood Transplantation
Not yet reported Massachusetts General Hospital 33 participants Est. completion 2017-06 3 sites Stand-aloneOther conditions: Non-Hodgkin's Lymphoma, Hodgkin's Lymphoma, Multiple Myeloma, Chronic Lymphocytic Leukemia, Acute Myelogenous LeukemiaView official trial listing → -
Completed NCT NCT01410344
Allogeneic Transplant in HIV Patients (BMT CTN 0903)
Not yet reported Medical College of Wisconsin 20 participants Est. completion 2018-06 11 sitesOther conditions: Leukemia, Lymphoma, HIVView official trial listing → -
Completed NCT NCT01422603
Clofarabine Pre-conditioning With Allogeneic Transplant for Acute Myeloid Leukaemia (AML)
Not yet reported, Not yet reported University Hospital Southampton NHS Foundation Trust 9 participants Est. completion 2015-03-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukaemia, MyelodysplasiaView official trial listing → -
Completed NCT NCT01423032
Bendamustine Versus Fludarabine in Chronic Lymphocytic Leukemia (CLL)
Not yet reported, Not yet reported WiSP Wissenschaftlicher Service Pharma GmbH 96 participants Est. completion 2009-05 1 siteOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT01423500
ALL-SCT BFM International- HSCT in Children and Adolescents With ALL
Not yet reported St. Anna Kinderkrebsforschung 405 participants Est. completion 2016-09 24 sitesOther conditions: Lymphoblastic Leukemia, Acute, Childhood;View official trial listing → -
Status unknown NCT NCT01423747
Allogeneic Stem Cell Transplantation in Children and Adolescents With Acute Lymphoblastic Leukaemia
Not yet reported St. Anna Kinderkrebsforschung 400 participants Est. completion 2016-09 24 sitesOther conditions: Lymphoblastic Leukemia, Acute, Childhood;View official trial listing → -
Completed NCT NCT01427881
Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies
Not yet reported Fred Hutchinson Cancer Center 43 participants Est. completion 2015-07 1 site Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Myeloid Leukemia in Remission, Adult Erythroleukemia (M6a), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Adult Pure Erythroid Leukemia (M6b), Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Blastic Phase Chronic Myelogenous Leukemia, Childhood Acute Erythroleukemia (M6), Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Megakaryocytic Leukemia (M7), Childhood Acute Myeloid Leukemia in Remission, Childhood Burkitt Lymphoma, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, de Novo Myelodysplastic Syndromes, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Noncutaneous Extranodal Lymphoma, Peripheral T-cell Lymphoma, Philadelphia Chromosome Negative Chronic Myelogenous Leukemia, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Relapsing Chronic Myelogenous Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Stage III Multiple Myeloma, Testicular Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Terminated NCT NCT01434472
High-Dose Y-90-Ibritumomab Tiuxetan Added to Reduced-Intensity Allogeneic Stem Cell Transplant Regimen for Relapsed or Refractory Aggressive B-Cell Lymphoma
Not yet reported Fred Hutchinson Cancer Center 20 participants Est. completion 2020-05-06 1 site Stand-aloneOther conditions: Post-Transplant Lymphoproliferative Disorder, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Burkitt Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Burkitt Lymphoma, Refractory Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT01435343
Treatment of Relapsed or Refractory Acute Myeloblastic Leukemia
Not yet reported, Not yet reported PETHEMA Foundation 55 participants Est. completion 2016-12 10 sitesOther conditions: Acute Myeloblastic LeukemiaView official trial listing → -
Completed NCT NCT01435447
Fludarabine/Busulfan and Cyclophosphamide Conditioning for Adult Lymphoid Malignancies
Not yet reported Shanghai Jiao Tong University School of Medicine 31 participants Est. completion 2018-10-01 1 site Stand-aloneOther conditions: Lymphoid MalignanciesView official trial listing → -
Terminated NCT NCT01445821
Autologous Stem Cell Systemic Sclerosis Immune Suppression Trial
Not yet reported Northwestern University 44 participants Est. completion 2019-10-10 1 site Stand-aloneOther conditions: Scleroderma, SystemicView official trial listing → -
Completed NCT NCT01451515
NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma
Not yet reported St. Jude Children's Research Hospital 23 participants Est. completion 2022-05-31 2 sitesOther conditions: Lymphoblastic LymphomaView official trial listing → -
Completed NCT NCT01453101
Allogeneic Hematopoietic Stem Cell Transplantation for Multiple Myeloma
Not yet reported Hackensack Meridian Health 54 participants Est. completion 2020-06-11 1 siteOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT01454596
CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII
Not yet reported, Not yet reported National Cancer Institute (NCI) 18 participants Est. completion 2019-01-17 1 site Stand-aloneObstructive sleep apnea Other conditions: Malignant Glioma, Glioblastoma, Brain CancerView official trial listing → -
Completed NCT NCT01455051
Ofatumumab as Part of Reduced Intensity Conditioning (RIC) Regimen for Patients With High Risk Chronic Lymphocytic Leukemia (CLL) Undergoing Allogeneic Hematopoietic Cell Transplantation
Not yet reported Grupo Espanol de trasplantes hematopoyeticos y terapia celular 25 participants Est. completion 2017-10 9 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT01455506
PRO#0118: Decitabine Plus Mini Flu-Bu
Not yet reported Hackensack Meridian Health 20 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01456351
Bendamustine Plus Rituximab Versus Fludarabine Plus Rituximab
Not yet reported University of Giessen 230 participants Est. completion 2010-12 1 siteOther conditions: Non-Hodgkin's Lymphoma, Mantle Cell LymphomaView official trial listing → -
Terminated NCT NCT01457131
Modified White Blood Cells That Secrete IL-2 and Express a Protein That Targets the ESO-1tumor Protein for Metastatic Cancer
Not yet reported National Cancer Institute (NCI) 2 participants Est. completion 2013-08-07 1 siteOther conditions: Metastatic Cancer, Metastatic Melanoma, Metastatic Renal CancerView official trial listing → -
Active, not recruiting NCT NCT01461837
Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease
Not yet reported New York Medical College 21 participants Est. completion 2026-12 6 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Terminated NCT NCT01464359
T-Cell Depleted Double UCB for Refractory AML
Not yet reported Masonic Cancer Center, University of Minnesota 3 participants Est. completion 2013-10 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Refractory Acute Myelogenous LeukemiaView official trial listing → -
Terminated NCT NCT01468818
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma
Not yet reported National Cancer Institute (NCI) 18 participants Est. completion 2013-08 1 site Stand-aloneOther conditions: Metastatic Melanoma, Skin CancerView official trial listing → -
Completed NCT NCT01471067
Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies
Not yet reported M.D. Anderson Cancer Center 33 participants Est. completion 2017-04-25 1 site Stand-aloneOther conditions: Blood And Marrow Transplantation, Leukemia, Lymphoma, Transplantation Infection, Transplantation, Bone MarrowView official trial listing → -
Completed NCT NCT01471444
Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
Not yet reported M.D. Anderson Cancer Center 256 participants Est. completion 2020-12-14 1 site Stand-aloneOther conditions: Disorder Related to Bone Marrow Transplantation, Leukemia, Transplantation InfectionView official trial listing → -
Status unknown NCT NCT01472055
Pharmacokinetic Study of Fludarabine in Pediatric Hematopoietic Stem Cell Transplantation
Not yet reported Seoul National University Hospital 46 participants Est. completion 2014-09 1 site Stand-aloneOther conditions: Acute Leukemia, Chronic Leukemia, Severe Aplastic AnemiaView official trial listing → -
Withdrawn NCT NCT01478074
ALT-801-activated Natural Killer Cells After FLAG Induction for Acute Myeloid Leukemia
Not yet reported Altor BioScience Est. completion 2013-11 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01484470
Umbilical Cord Transplantation for the Elderly Population
Not yet reported Loyola University 18 participants Est. completion 2018-11-21 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT01490723
Zevalin-Containing Nonmyeloablative Conditioning for Stem Cell Transplantation (SCT)
Not yet reported M.D. Anderson Cancer Center 20 participants Est. completion 2019-04-24 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT01493453
A Phase I Study of CD19 Specific T Cells in CD19 Positive Malignancy
Not yet reported The Christie NHS Foundation Trust 17 participants Est. completion 2019-06 1 site Stand-aloneOther conditions: CD19 Positive Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT01497002
Comparison of the OSHO Protocol to a Standard Arm Protocol of the German AML Intergroup in Patients With AML>60a
Not yet reported University of Leipzig 1222 participants Est. completion 2018-07-18 1 site Stand-aloneOther conditions: Acute Myeloid LeukaemiaView official trial listing → -
Completed NCT NCT01499147
Fludarabine Based Conditioning for Allogeneic Transplantation for Advanced Hematologic Malignancies
Not yet reported University of Illinois at Chicago 100 participants Est. completion 2013-05 1 siteOther conditions: Acute Myeloid Leukemia, Acute Leukemia, Chronic Myelogenous Leukemia, Malignant Lymphoma, Hodgkin's Disease, Multiple Myeloma, Lymphocytic Leukemia, Myeloproliferative Disorder, Polycythemia Vera, Myelofibrosis, Aplastic AnemiaView official trial listing → -
Terminated NCT NCT01500161
Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing Allogeneic Stem Cell Transplant Without Related HLA-Match
Not yet reported Texas Oncology Cancer Center 1 participants Est. completion 2013-11 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Hodgkins Disease, Non-Hodgkins Lymphoma, Aplastic Anemia, Multiple Myeloma, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01503242
90 Y-BC8-DOTA Monoclonal Antibody, Fludarabine Phosphate, and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Multiple Myeloma
Not yet reported Fred Hutchinson Cancer Center 15 participants Est. completion 2019-12-06 1 site Stand-aloneOther conditions: Plasma Cell Myeloma, Refractory Plasma Cell MyelomaView official trial listing → -
Status unknown NCT NCT01509300
HLA-haploidentical Hematopoietic Stem Cell Transplantation for Children and Adolescents With Acute Leukemia, Myelodysplastic Syndrome and Solid Tumors
Not yet reported, Not yet reported Asan Medical Center 10 participants Est. completion 2014-03 1 site Stand-aloneOther conditions: Acute Leukemia, Myelodysplastic Syndrome, Solid TumorsView official trial listing → -
Terminated NCT NCT01518153
Planned Donor Lymphocyte Infusion (DLI) After Allogeneic Stem Cell Transplantation (SCT)
Not yet reported M.D. Anderson Cancer Center 16 participants Est. completion 2014-08 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, Myeloma, Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT01527045
Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies
Not yet reported Fred Hutchinson Cancer Center 47 participants Est. completion 2019-04 2 sites Stand-aloneOther conditions: Aggressive Non-Hodgkin Lymphoma, Blasts Under 5 Percent of Bone Marrow Nucleated Cells, Chronic Lymphocytic Leukemia, Loss of Chromosome 17p, Myelodysplastic/Myeloproliferative Neoplasm, Non-Hodgkin Lymphoma, Prolymphocytic Leukemia, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Aggressive Adult Non-Hodgkin Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Hodgkin Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Non-Hodgkin Lymphoma, Recurrent Plasma Cell Myeloma, Recurrent Small Lymphocytic Lymphoma, Waldenstrom MacroglobulinemiaView official trial listing → -
Completed NCT NCT01529827
Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
Not yet reported Roswell Park Cancer Institute 94 participants Est. completion 2019-08-29 1 site Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Aplastic Anemia, Burkitt Lymphoma, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Diffuse Large Cell Lymphoma, Childhood Grade III Lymphomatoid Granulomatosis, Childhood Immunoblastic Large Cell Lymphoma, Childhood Myelodysplastic Syndromes, Childhood Nasal Type Extranodal NK/T-cell Lymphoma, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, Congenital Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Hepatosplenic T-cell Lymphoma, Juvenile Myelomonocytic Leukemia, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Paroxysmal Nocturnal Hemoglobinuria, Peripheral T-cell Lymphoma, Polycythemia Vera, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Primary Myelofibrosis, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Childhood Anaplastic Large Cell Lymphoma, Recurrent Childhood Grade III Lymphomatoid Granulomatosis, Recurrent Childhood Large Cell Lymphoma, Recurrent Childhood Lymphoblastic Lymphoma, Recurrent Childhood Small Noncleaved Cell Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Recurrent/Refractory Childhood Hodgkin Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Secondary Myelofibrosis, Severe Combined Immunodeficiency, Severe Congenital Neutropenia, Shwachman-Diamond Syndrome, Splenic Marginal Zone Lymphoma, T-cell Large Granular Lymphocyte Leukemia, Waldenstrom Macroglobulinemia, Wiskott-Aldrich SyndromeView official trial listing → -
Terminated NCT NCT01534143
High Dose Busulfan and Bortezomib in Treating Patients With High Risk Multiple Myeloma Undergoing Stem Cell Transplant
Not yet reported Barbara Ann Karmanos Cancer Institute 1 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple MyelomaView official trial listing → -
Completed NCT NCT01540812
Treatment of Acute Lymphoblastic Leukemia HIGH RISK BCR / ABL NEGATIVE IN ADULTS
PETHEMA Foundation 418 participants Est. completion 2019-12-01 1 siteOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01560117
Combination of Oral Fludarabine, Mitoxantrone Und Rituximab Induction Therapy and Rituximab Maintenance Therapy in Follicular B-Cell Lymphoma
Not yet reported Arbeitsgemeinschaft medikamentoese Tumortherapie 29 participants Est. completion 2010-07Other conditions: Follicular T-NHL Lymphoma, Rituximab MaintenanceView official trial listing → -
Completed NCT NCT01564784
A Study Of Inotuzumab Ozogamicin Versus Investigator's Choice Of Chemotherapy In Patients With Relapsed Or Refractory Acute Lymphoblastic Leukemia
Not yet reported Pfizer 326 participants Est. completion 2017-01-04 198 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01565616
Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease
Not yet reported Emory University 22 participants Est. completion 2016-06-30 8 sitesOther conditions: Sickle Cell DiseaseView official trial listing → -
Terminated NCT NCT01570348
Crohn's Allogeneic Transplant Study
Not yet reported Fred Hutchinson Cancer Center 2 participants Est. completion 2019-10-30 1 site Stand-aloneOther conditions: Crohn DiseaseView official trial listing → -
Completed NCT NCT01572181
Study of a Reduced-toxicity Myeloablative Conditioning Regimen Using Fludarabine and Full Doses of Intravenous Busulfan in Pediatric Patients Not Eligible for Standard Myeloablative Conditioning Regimens
Not yet reported Nantes University Hospital 50 participants Est. completion 2017-10-24 15 sites Stand-aloneOther conditions: Hematologic MalignancyView official trial listing → -
Completed NCT NCT01572662
Allogeneic Transplantation Using Timed Sequential Busulfan and Fludarabine Conditioning
Not yet reported M.D. Anderson Cancer Center 201 participants Est. completion 2022-08-11 1 site Stand-aloneOther conditions: Leukemia, Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia, Myeloproliferative Diseases, Non-Hodgkins Lymphoma, Hodgkins Lymphoma, Multiple Myeloma, Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT01578343
Vorinostat Plus FND in Relapsed or Refractory Mantle Cell Lymphoma
Not yet reported Samsung Medical Center 20 participants Est. completion 2016-02 1 site Stand-aloneOther conditions: Mantle Cell LymphomaView official trial listing → -
Terminated NCT NCT01582048
Multicenter Study of Peritransplantation Immunosuppression for Mismatched Hematopoietic Cell Transplantation After Reduced Intensity Conditioning
Not yet reported Prof. Dr. med. Wolfgang Bethge 9 participants Est. completion 2016-08-17 4 sitesOther conditions: Patients Receiving Mismatched Allogeneic HCTView official trial listing → -
Terminated NCT NCT01583686
CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 15 participants Est. completion 2018-12-17 1 site Stand-aloneOther conditions: Cervical Cancer, Pancreatic Cancer, Ovarian Cancer, Mesothelioma, Lung CancerView official trial listing → -
Terminated NCT NCT01585415
Vemurafenib and White Blood Cell Therapy for Advanced Melanoma
Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2016-07-21 1 site Stand-aloneOther conditions: Metastatic Cancer, MelanomaView official trial listing → -
Completed NCT NCT01585428
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Human Papillomavirus-Associated Cancers
Not yet reported National Cancer Institute (NCI) 29 participants Est. completion 2016-08-01 1 site Stand-aloneOther conditions: Cervical Cancer, Oropharyngeal Cancer, Vaginal Cancer, Anal Cancer, Penile CancerView official trial listing → -
Completed NCT NCT01592981
Randomised Trial in Waldenstrom's Macroglobulinaemia
Not yet reported University College, London 60 participants Est. completion 2020-08-02 30 sitesOther conditions: Waldenstrom's MacroglobulinaemiaView official trial listing → -
Completed NCT NCT01593696
Anti-CD19 White Blood Cells for Children and Young Adults With B Cell Leukemia or Lymphoma
Not yet reported National Cancer Institute (NCI) 53 participants Est. completion 2017-10-02 1 site Stand-aloneOther conditions: ALL, B Cell Lymphoma, Leukemia, Large Cell Lymphoma, Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT01597219
Trial of Haploidentical Stem Cell Transplantation for Haematological Cancers
Not yet reported University College, London 77 participants Est. completion 2024-01 12 sites Stand-aloneOther conditions: Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Acute Myeloid Leukaemia, Acute Lymphoblastic Leukaemia, Myelodysplastic Syndrome, Chronic Myeloid Leukaemia, Chronic Lymphocytic Leukaemia, Acquired Bone Marrow Failure Syndromes, Other Haematological Malignancies; Unrelated HSCT IndicatedView official trial listing → -
Completed NCT NCT01597778
Double Cord Versus Haploidentical (BMT CTN 1101)
Not yet reported Medical College of Wisconsin 368 participants Est. completion 2020-09-11 39 sites Stand-aloneOther conditions: Acute Lymphocytic Leukemia, Acute Myelogenous Leukemia, Burkitt's Lymphoma, Follicular Lymphoma, Hodgkin Lymphoma, Mantle Cell Lymphoma, Non-Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT01598025
Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor
Not yet reported Memorial Sloan Kettering Cancer Center 3 participants Est. completion 2017-10-16 1 site Stand-aloneOther conditions: Acute Leukemia, Chronic Leukemia, Myelodysplastic Syndrome, Non-Hodgkins LymphomaView official trial listing → -
Status unknown NCT NCT01619761
NK Cells in Cord Blood Transplantation
Not yet reported M.D. Anderson Cancer Center 13 participants Est. completion 2021-11 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, DS Stage II Plasma Cell Myeloma, DS Stage III Plasma Cell Myeloma, High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, ISS Stage II Plasma Cell Myeloma, ISS Stage III Plasma Cell Myeloma, Myelodysplastic Syndrome, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Hodgkin Lymphoma, Recurrent Non-Hodgkin Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory Acute Lymphoblastic Leukemia, Refractory Chronic Lymphocytic Leukemia, Refractory Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Refractory Small Lymphocytic Lymphoma, Secondary Acute Myeloid Leukemia, Therapy-Related Acute Myeloid Leukemia, Therapy-Related Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT01621477
T-Cell Replete Haploidentical Donor Hematopoietic Stem Cell Plus Natural Killer (NK) Cell Transplantation in Patients With Hematologic Malignancies Relapsed or Refractory Despite Previous Allogeneic Transplant
Not yet reported St. Jude Children's Research Hospital 34 participants Est. completion 2015-12 1 siteOther conditions: Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia, Chronic Myelocytic Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndrome, Hodgkin or Non-Hodgkin Lymphoma, Sarcoma, MyeloidView official trial listing → -
Terminated NCT NCT01622556
Conditioning Treatment With Umbilical Cord Blood Transplant for Hematologic Malignancies
Not yet reported University of Virginia 6 participants Est. completion 2017-01 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT01625351
A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas
Not yet reported St. Jude Children's Research Hospital 23 participants Est. completion 2020-02-10 1 site Stand-aloneObstructive sleep apnea Other conditions: Ewing Sarcoma, Gastrointestinal Tumor, Germ Cell Tumor, Hepatic Tumor, Lymphoma, Wilms Tumor, Rhabdoid Tumor, Clear Cell Carcinoma, Renal Cell Carcinoma, Melanoma, NeuroblastomaView official trial listing → -
Withdrawn NCT NCT01639456
CD3/CD19 Depleted or CD3 Depleted/CD56 Selected Haploid Donor Natural Killer Cell Treatment in Older AML in First Complete Remission
Not yet reported Masonic Cancer Center, University of Minnesota Est. completion 2017-01 2 sites Stand-aloneOther conditions: Acute Myelogenous LeukemiaView official trial listing → -
Terminated NCT NCT01640301
Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 47 participants Est. completion 2020-03-20 1 site Stand-aloneOther conditions: Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Therapy-Related Acute Myeloid Leukemia, Donor, Hematopoietic Cell Transplant Recipient, HLA-A*0201 Positive Cells Present, Recurrent Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT01652014
Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies
Not yet reported University of Medicine and Dentistry of New Jersey Est. completion 2017-01 1 site Stand-aloneObstructive sleep apnea Other conditions: Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Blastic Phase Chronic Myelogenous Leukemia, Cutaneous B-cell Non-Hodgkin Lymphoma, de Novo Myelodysplastic Syndromes, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Myelodysplastic/Myeloproliferative Neoplasm, Unclassifiable, Nodal Marginal Zone B-cell Lymphoma, Noncutaneous Extranodal Lymphoma, Peripheral T-cell Lymphoma, Post-transplant Lymphoproliferative Disorder, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Hairy Cell Leukemia, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndromes, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, T-cell Large Granular Lymphocyte Leukemia, Testicular Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Active, not recruiting NCT NCT01652092
Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune Deficiencies
Not yet reported Masonic Cancer Center, University of Minnesota 57 participants Est. completion 2026-12 1 siteOther conditions: SCID, Omenn's Syndrome, Reticular Dysgenesis, Wiskott-Aldrich Syndrome, Bare Lymphocyte Syndrome, Common Variable Immunodeficiency, Chronic Granulomatous Disease, CD40 Ligand Deficiency, Hyper IgM Syndrome, X-linked Lymphoproliferative Disease, Hemophagocytic Lymphohistiocytosis, Griscelli Syndrome, Chediak-Higashi Syndrome, Langerhan's Cell HistiocytosisView official trial listing → -
Completed NCT NCT01653717
CD19-specific T-cell for Chronic Lymphocytic Leukemia (CLL)
Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2017-08-07 1 site Stand-aloneOther conditions: Advanced Cancers, LeukemiaView official trial listing → -
Completed NCT NCT01658319
Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies
Not yet reported Case Comprehensive Cancer Center 20 participants Est. completion 2015-05 1 site Stand-aloneObstructive sleep apnea Other conditions: Adult Nasal Type Extranodal NK/T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Cutaneous B-cell Non-Hodgkin Lymphoma, Hepatosplenic T-cell Lymphoma, Intraocular Lymphoma, Nodal Marginal Zone B-cell Lymphoma, Peripheral T-cell Lymphoma, Recurrent Adult Burkitt Lymphoma, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Adult Diffuse Mixed Cell Lymphoma, Recurrent Adult Diffuse Small Cleaved Cell Lymphoma, Recurrent Adult Grade III Lymphomatoid Granulomatosis, Recurrent Adult Hodgkin Lymphoma, Recurrent Adult Immunoblastic Large Cell Lymphoma, Recurrent Adult Lymphoblastic Lymphoma, Recurrent Adult T-cell Leukemia/Lymphoma, Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Mycosis Fungoides/Sezary Syndrome, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Multiple Myeloma, Relapsing Chronic Myelogenous Leukemia, Small Intestine Lymphoma, Splenic Marginal Zone Lymphoma, Stage III Chronic Lymphocytic Leukemia, Testicular Lymphoma, Waldenström MacroglobulinemiaView official trial listing → -
Completed NCT NCT01659151
Vemurafenib With Lymphodepletion Plus Adoptive Cell Transfer & High Dose IL-2 Metastatic Melanoma
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 17 participants Est. completion 2025-08-19 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Active, not recruiting NCT NCT01659606
Radiation- and Alkylator-free Bone Marrow Transplantation Regimen for Patients With Dyskeratosis Congenita
Not yet reported Boston Children's Hospital 40 participants Est. completion 2034-12 13 sites Stand-aloneOther conditions: Dyskeratosis Congenita, Hoyeraal Hreidarsson Syndrome, Revesz Syndrome, Aplastic AnemiaView official trial listing → -
Terminated NCT NCT01663766
Phase I Study of Milatuzumab for Graft Versus Host Disease
Not yet reported Gilead Sciences 12 participants Est. completion 2015-03 1 site Stand-aloneOther conditions: GVHD (Acute or Chronic), Acute Myeloid or Lymphoblastic Leukemia (AML or ALL), Myelodysplastic Syndrome, Chronic Myelogenous Leukemia (CML), Multiple Myeloma (MM), Non-Hodgekin Lymphoma (NHL-both Follicular & Diffuse Large Cell), Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia (CLL or SLL)View official trial listing → -
Completed NCT NCT01664910
CMC-544 and Allogeneic Transplantation for CD22 Positive-Lymphoid Malignancies
Not yet reported, Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2023-06-28 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell NeoplasmView official trial listing → -
Terminated NCT NCT01679041
High Dose Chemo With Stem Cell Transplant as Treatment for Multiple Sclerosis That Failed Prior Treatment
Not yet reported Seah Lim M.D. 1 participants Est. completion 2013-11 3 sites Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Completed NCT NCT01682226
Cord Blood With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cell Transplantation for Hematological Malignancies
Not yet reported Memorial Sloan Kettering Cancer Center 84 participants Est. completion 2021-01-08 1 site Stand-aloneOther conditions: Leukemia, Myelodysplastic Syndrome, LymphomaView official trial listing → -
Completed NCT NCT01683123
Study With Intravenous Busulfan And Fludarabine Myeloablative Conditioning Regimen For HLA Identical Sibling Donor HSCT
Grupo Espanol de trasplantes hematopoyeticos y terapia celular 143 participants Est. completion 2012-10Other conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome, Myeloproliferative Disorders, Chronic Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01690520
Donor Umbilical Cord Blood Transplant With or Without Ex-vivo Expanded Cord Blood Progenitor Cells in Treating Patients With Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, or Myelodysplastic Syndromes
Not yet reported Nohla Therapeutics, Inc. 163 participants Est. completion 2020-05-29 8 sites Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission, Chronic Myelogenous Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01696461
A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor
Not yet reported Center for International Blood and Marrow Transplant Research 127 participants Est. completion 2016-08 12 sitesOther conditions: Related Donors Donating Peripheral Blood Stem Cells (PBSC) to a Family Member, Acute Myelogenous Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndrome, Chronic Myelogenous Leukemia, Non-Hodgkin's Lymphoma, Hodgkin's Disease, Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT01697527
Gene and Vaccine Therapy in Treating Patients With Advanced Malignancies
Not yet reported Jonsson Comprehensive Cancer Center 6 participants Est. completion 2027-11-02 1 site Stand-aloneOther conditions: Malignant NeoplasmView official trial listing → -
Terminated NCT NCT01701323
Expanded Cord Blood Cell Infusion Following Combination Chemotherapy in Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported Nohla Therapeutics, Inc. 7 participants Est. completion 2018-05-10 2 sites Stand-aloneOther conditions: Acute Leukemia of Ambiguous Lineage, Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01701674
Ipilimumab With Lymphodepletion Plus Adoptive Cell Transfer and High Dose IL-2 in Melanoma Mets Pts
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 13 participants Est. completion 2025-08-21 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT01707004
Decitabine and Total-Body Irradiation Followed By Donor Bone Marrow Transplant and Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported University of Wisconsin, Madison 20 participants Est. completion 2017-10-07 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Myeloid Leukemia in Remission, Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), de Novo Myelodysplastic Syndromes, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Myeloid Leukemia, Secondary Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01723839
Phase II Protocol for CLL With Fludarabine and Cyclophosphamide With Rituximab (FCR) Plus Lenalidomide
Not yet reported Hackensack Meridian Health 21 participants Est. completion 2021-06-08 1 siteOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Completed NCT NCT01740557
Genetically Modified Therapeutic Autologous Lymphocytes Followed by Aldesleukin in Treating Patients With Stage III or Metastatic Melanoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 10 participants Est. completion 2023-04-21 1 site Stand-aloneOther conditions: Metastatic Melanoma, Stage III Cutaneous Melanoma AJCC v7, Stage IV Cutaneous Melanoma AJCC v6 and v7View official trial listing → -
Terminated NCT NCT01745913
Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies
Not yet reported Weill Medical College of Cornell University 2 participants Est. completion 2015-04-29 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Acute Lymphocytic Leukemia, Hodgkin's Lymphoma, Non-Hodgkin's LymphomaView official trial listing → -
Terminated NCT NCT01749293
Partially HLA Mismatched (Haploidentical) Allogeneic Bone Marrow Transplantation
Not yet reported University of Illinois at Chicago 3 participants Est. completion 2014-05-15 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Completed NCT NCT01751997
Family-mismatched/Haploidentical Donors Versus Matched Unrelated Donors
Not yet reported, Not yet reported Byung-Sik Cho 116 participants Est. completion 2019-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01758328
Dose Escalation Trial of WT1-specific Donor-derived T Cells Following T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Relapsed/Refractory Multiple Myeloma
Not yet reported Memorial Sloan Kettering Cancer Center 29 participants Est. completion 2025-03-17 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT01759732
Haploidentical Stem Cell Transplantation for Children With Acquired Severe Aplastic Anemia
Not yet reported Asan Medical Center 10 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: Acquired Aplastic AnemiaView official trial listing → -
Completed NCT NCT01760655
Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 62 participants Est. completion 2022-12-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia With FLT3/ITD Mutation, Acute Myeloid Leukemia With Gene Mutations, Acute Myeloid Leukemia With Inv(3) (q21.3;q26.2); GATA2, MECOM, Acute Myeloid Leukemia With t(6;9) (p23;q34.1); DEK-NUP214, Aplastic Anemia, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Myelomonocytic Leukemia, Follicular Lymphoma, Hodgkin Lymphoma, Myelodysplastic Syndrome, Myelofibrosis, Myeloid Leukemia, Non-Hodgkin Lymphoma, Plasma Cell Myeloma, Polycythemia Vera, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Therapy-Related Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01762202
Assessment of Efficacy and Safety of Front-line Fludarabine, Cyclophoshamide and Ofatumumab Chemoimmunotherapy in Young Patients With Chronic Lymphocytic Leukemia.
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 80 participants Est. completion 2018-10 22 sites Stand-aloneOther conditions: B-cell Lymphoid Leukemia, Young PatientsView official trial listing → -
Completed NCT NCT01772953
Treosulfan/Fludarabine/Low Dose TBI as a Preparative Regimen for Children With AML/MDS Undergoing Allo HCT
Not yet reported Center for International Blood and Marrow Transplant Research 40 participants Est. completion 2015-08 23 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)View official trial listing → -
Terminated NCT NCT01773395
GVAX vs. Placebo for MDS/AML After Allo HSCT
Not yet reported Dana-Farber Cancer Institute 123 participants Est. completion 2021-11-24 4 sitesOther conditions: Myelodysplastic Syndrome, Acute Myeloid Leukemia, Chronic Myelomonocytic LeukemiaView official trial listing → -
Completed NCT NCT01785810
Phase II Maraviroc for GVHD Prevention
Not yet reported Abramson Cancer Center at Penn Medicine 37 participants Est. completion 2018-07-12 1 site Stand-aloneOther conditions: Hematologic MalignancyView official trial listing → -
Completed NCT NCT01787474
Donor Natural Killer Cells in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2021-06-17 1 site Stand-aloneOther conditions: Recurrent Adult Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT01795976
NY-ESO-1 T Cells in OG Cancer
Not yet reported Fiona Thistlethwaite 2 participants Est. completion 2017-11 1 site Stand-aloneOther conditions: Oesophageal CancerView official trial listing → -
Completed NCT NCT01807182
Tumor-Infiltrating Lymphocytes After Combination Chemotherapy in Treating Patients With Metastatic Melanoma
Not yet reported Fred Hutchinson Cancer Center 11 participants Est. completion 2021-08-26 1 site Stand-aloneOther conditions: Stage III Cutaneous Melanoma AJCC v7, Stage IIIA Cutaneous Melanoma AJCC v7, Stage IIIB Cutaneous Melanoma AJCC v7, Stage IIIC Cutaneous Melanoma AJCC v7, Stage IV Cutaneous Melanoma AJCC v6 and v7, Metastatic MelanomaView official trial listing → -
Completed NCT NCT01807611
Haploidentical Donor Hematopoietic Progenitor Cell and NK Cell Transplantation for Hematologic Malignancy
Not yet reported St. Jude Children's Research Hospital 82 participants Est. completion 2021-09-27 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Completed NCT NCT01810588
Targeting the IPA and Matching for the Non-Inherited Maternal Antigen for Haplo-Cord Transplantation
Not yet reported Weill Medical College of Cornell University 270 participants Est. completion 2026-03-24 2 sites Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Status unknown NCT NCT01810926
T&B Depletion Non Malignant
Not yet reported Franco Locatelli 130 participants Est. completion 2016-10 4 sites Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Terminated NCT NCT01814046
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Ocular Melanoma
Not yet reported National Cancer Institute (NCI) 24 participants Est. completion 2017-05-31 1 site Stand-aloneOther conditions: Metastatic Ocular Melanoma, Metastatic Uveal MelanomaView official trial listing → -
Completed NCT NCT01814475
Study to Compare Busulfan-fludarabine With Thiotepa-fludarabine Regimen in Allogeneic Transplantation for Myelofibrosis
Not yet reported Gruppo Italiano Trapianto di Midollo Osseo 62 participants Est. completion 2016-12-31 21 sites Stand-aloneOther conditions: MyelofibrosisView official trial listing → -
Completed NCT NCT01814488
A Phase II Study on Allogeneic Stem Cell Transplantation in Patients With Active Acute Leukemia
Not yet reported Gruppo Italiano Trapianto di Midollo Osseo 101 participants Est. completion 2017-06-30 30 sites Stand-aloneOther conditions: Acute LeukemiaView official trial listing → -
Status unknown NCT NCT01818323
Phase I Trial: T4 Immunotherapy of Head and Neck Cancer
Not yet reported King's College London 30 participants Est. completion 2025-01 1 site Stand-aloneOther conditions: Head and Neck CancerView official trial listing → -
Active, not recruiting NCT NCT01821781
Immune Disorder HSCT Protocol
Not yet reported Washington University School of Medicine 20 participants Est. completion 2026-04 1 site Stand-aloneOther conditions: Immune Deficiency Disorders, Severe Combined Immunodeficiency, Chronic Granulomatous Disease, X-linked Agammaglobulinemia, Wiskott-Aldrich Syndrome, Hyper-IgM, DiGeorge Syndrome, Chediak-Higashi Syndrome, Common Variable Immune Deficiency, Immune Dysregulatory Disorders, Hemophagocytic Lymphohistiocytosis, IPEX, Autoimmune Lymphoproliferative Syndrome, X-linked Lymphoproliferative SyndromeView official trial listing → -
Active, not recruiting NCT NCT01822652
3rd Generation GD-2 Chimeric Antigen Receptor and iCaspase Suicide Safety Switch, Neuroblastoma, GRAIN
Not yet reported Baylor College of Medicine 11 participants Est. completion 2030-10 2 sites Stand-aloneOther conditions: NeuroblastomaView official trial listing → -
Completed NCT NCT01823198
Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies
Not yet reported, Not yet reported M.D. Anderson Cancer Center 63 participants Est. completion 2022-05-10 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Erythroid Leukemia, Acute Megakaryoblastic Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Acute Myeloid Leukemia in Remission, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Blasts Under 20 Percent of Bone Marrow Nucleated Cells, Blasts Under 20 Percent of Peripheral Blood White Cells, Chronic Myelomonocytic Leukemia, High Risk Myelodysplastic Syndrome, Myelodysplastic Syndrome, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Therapy-Related Acute Myeloid Leukemia, Therapy-Related Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT01824693
Busulfan, Cyclophosphamide, and Melphalan or Busulfan and Fludarabine Phosphate Before Donor Hematopoietic Cell Transplant in Treating Younger Patients With Juvenile Myelomonocytic Leukemia
Not yet reported Children's Oncology Group 30 participants Est. completion 2017-12-31 50 sites Stand-aloneOther conditions: Juvenile Myelomonocytic LeukemiaView official trial listing → -
Status unknown NCT NCT01828619
Study of New RIC Regimen of BuFlu in Older and/or Intolerable Patients
Peking University People's Hospital 60 participants 1 siteOther conditions: Leukemia, Myelodysplastic SyndromeView official trial listing → -
Status unknown NCT NCT01850108
Non-Myeloablative Conditioning and Bone Marrow Transplantation
Not yet reported Vanderbilt-Ingram Cancer Center 26 participants Est. completion 2024-12-31 3 sites Stand-aloneOther conditions: Sickle Cell Disease, HemoglobinopathiesView official trial listing → -
Completed NCT NCT01858740
Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children
Not yet reported Fred Hutchinson Cancer Center 20 participants Est. completion 2023-07-30 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Leukemia of Ambiguous Lineage, Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Myelodysplastic Syndrome With Excess Blasts-1, Myelodysplastic Syndrome With Excess Blasts-2, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Refractory Adult Acute Lymphoblastic Leukemia, Refractory Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT01860170
Post-Transplant Bortezomib and High Dose Cyclophosphamide as Graft-Versus-Host Disease (GVHD) Prophylaxis
Not yet reported, Not yet reported Corewell Health West 28 participants Est. completion 2018-03 1 siteOther conditions: Hematological MalignancyView official trial listing → -
Completed NCT NCT01861002
A Phase I Study of 5-Azacytidine in Combination With Chemotherapy for Children With Relapsed or Refractory ALL or AML
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 15 participants Est. completion 2014-07-28 23 sites Stand-aloneOther conditions: Lymphoblastic Leukemia, Acute, Childhood, Myelogenous Leukemia, Acute, ChildhoodView official trial listing → -
Completed NCT NCT01866839
Preventing Stem Cell Transplant Complications With a Blood Separator Machine
Not yet reported, Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 41 participants Est. completion 2018-06-28 1 site Stand-aloneOther conditions: MDS (Myelodysplastic Syndrome), Myeloproliferative Disorder, Lymphoma, Non-Hodgkin, ALL (Acute B-Lymphoblastic Leukemia), AML (Acute Myelogenous LeukemiaView official trial listing → -
Terminated NCT NCT01875237
Donor Lymphocyte Infusion (DLI) of T-cells Genetically Modified With iCasp9 Suicide Gene
Not yet reported, Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2017-03-07 1 site Stand-aloneOther conditions: Leukemia, Myeloma, Myeloproliferative DiseasesView official trial listing → -
Completed NCT NCT01877837
Stem Cell Transplantation for Sickle Cell Anemia
Not yet reported Hackensack Meridian Health 30 participants Est. completion 2021-09 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Completed NCT NCT01883323
Tumor-Infiltrating Lymphocytes And Low-Dose Interleukin-2 Therapy Following Cyclophosphamide And Fludarabine In Patients With Melanoma
Not yet reported University Health Network, Toronto 12 participants Est. completion 2018-04 1 site Stand-aloneOther conditions: Metastatic, Stage III or Stage IV, MelanomaView official trial listing → -
Status unknown NCT NCT01894477
Treo/Flu/TBI With Donor Stem Cell Transplant for Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia
Not yet reported Fred Hutchinson Cancer Center 102 participants Est. completion 2022-06 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia in Remission, Chronic Myelomonocytic Leukemia, Minimal Residual Disease, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm, Myelodysplastic/Myeloproliferative Neoplasm, UnclassifiableView official trial listing → -
Terminated NCT NCT01898793
Cytokine-induced Memory-like NK Cells in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Not yet reported, Not yet reported Washington University School of Medicine 89 participants Est. completion 2022-04-04 1 site Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Completed NCT NCT01904136
Natural Killer Cells Before and After Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 54 participants Est. completion 2022-02-28 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Acute Myeloid Leukemia With Gene Mutations, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, de Novo Myelodysplastic Syndrome, Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Therapy-Related Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01905943
A Safety and Efficacy Study of Obinutuzumab Alone or in Combination With Chemotherapy in Participants With Chronic Lymphocytic Leukemia
Not yet reported Hoffmann-La Roche 979 participants Est. completion 2018-10-08 174 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT01946373
T Cell Transfer With or Without Dendritic Cell Vaccination in Patients With Melanoma
Not yet reported Karolinska University Hospital 20 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: MelanomaView official trial listing → -
Completed NCT NCT01947322
Haploidentical NK-cell Infusion in Acute Myeloid Leukemia
Not yet reported, Not yet reported Assistance Publique - Hôpitaux de Paris 10 participants Est. completion 2016-01 4 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT01953900
iC9-GD2-CAR-VZV-CTLs/Refractory or Metastatic GD2-positive Sarcoma and Neuroblastoma
Not yet reported Baylor College of Medicine 26 participants Est. completion 2034-10-31 2 sites Stand-aloneObstructive sleep apnea Other conditions: NeuroblastomaView official trial listing → -
Terminated NCT NCT01954784
Lenalidomide After Donor Stem Cell Transplant and Bortezomib in Treating Patients With High Risk Multiple Myeloma
Not yet reported Case Comprehensive Cancer Center 8 participants Est. completion 2017-01-30 1 site Stand-aloneOther conditions: Refractory Multiple Myeloma, Stage I Multiple Myeloma, Stage II Multiple Myeloma, Stage III Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT01955460
Genetically Modified T-Cells Followed by Aldesleukin in Treating Patients With Stage III-IV Melanoma
Not yet reported M.D. Anderson Cancer Center 34 participants Est. completion 2027-10-30 1 site Stand-aloneOther conditions: Metastatic Melanoma, Stage III Cutaneous Melanoma AJCC v7, Stage IIIA Cutaneous Melanoma AJCC v7, Stage IIIB Cutaneous Melanoma AJCC v7, Stage IIIC Cutaneous Melanoma AJCC v7, Stage IV Cutaneous Melanoma AJCC v6 and v7View official trial listing → -
Terminated NCT NCT01962636
Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases
Not yet reported Masonic Cancer Center, University of Minnesota 200 participants Est. completion 2026-05-14 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelofibrosis, Myelodysplasia, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone B-Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Leukemia, Diffuse Large B Cell Lymphoma, Lymphoblastic Lymphoma, Burkitt's Lymphoma, Non-Hodgkin Lymphoma, Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT01966367
CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation
Not yet reported, Not yet reported Diane George 37 participants Est. completion 2030-02 1 site Stand-aloneOther conditions: Bone Marrow Failure Syndrome, Severe Aplastic Anemia, Severe Congenital Neutropenia, Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Schwachman Diamond Syndrome, Primary Immunodeficiency Syndromes, Acquired Immunodeficiency Syndromes, Histiocytic Syndrome, Familial Hemophagocytic Lymphocytosis, Lymphohistiocytosis, Macrophage Activation Syndrome, Langerhans Cell Histiocytosis (LCH), Hemoglobinopathies, Sickle Cell Disease, Sickle Cell-beta-thalassemiaView official trial listing → -
Completed NCT NCT01967823
T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer
Not yet reported National Cancer Institute (NCI) 11 participants Est. completion 2020-04-06 1 site Stand-aloneOther conditions: Melanoma, Meningioma, Breast Cancer, Non-Small Cell Lung Cancer, Hepatocellular CancerView official trial listing → -
Withdrawn NCT NCT01969942
A Phase I Study to Examine the Toxicity of Allogeneic Stem Cell Transplantation for Relapsed or Therapy Refractory Ewing Sarcoma
Not yet reported University of Louisville Est. completion 2016-10 1 site Stand-aloneOther conditions: Ewing SarcomaView official trial listing → -
Suspended NCT NCT01974479
Pilot Study of Redirected Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemia
Not yet reported National University Health System, Singapore 20 participants Est. completion 2020-02 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT01983761
Study of ASC-101 in Patients With Hematologic Malignancies Who Receive Dual-cord Umbilical Cord Blood Transplantation
Not yet reported, Not yet reported Targazyme, Inc. 25 participants 4 sites Stand-aloneOther conditions: Blood And Marrow Transplantation, Leukemia, Lymphoma, Transplantation Infection, Myelodysplastic Syndrome (MDS), Non-Hodgkin's Lymphoma (NHL), Hodgkin's LymphomaView official trial listing → -
Completed NCT NCT01985061
Evaluation of 3 Different Doses of IV Busulfan
Not yet reported Institut Paoli-Calmettes 177 participants Est. completion 2026-05-27 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT01991457
Fludarabine / Total Body Irradiation Regimen for ALLO HCT in Acute Lymphoblastic Leukemia
Not yet reported University of Alabama at Birmingham 19 participants Est. completion 2022-08-23 1 siteOther conditions: Adult Lymphoblastic LymphomaView official trial listing → -
Terminated NCT NCT01995344
TIL Therapy in Metastatic Melanoma and IL2 Dose Assessment
Not yet reported The Christie NHS Foundation Trust 2 participants Est. completion 2015-07-24 1 siteOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT01998633
Reduced Intensity Conditioning for Hemophagocytic Syndromes or Selected Primary Immune Deficiencies (BMT CTN 1204)
Not yet reported Medical College of Wisconsin 47 participants Est. completion 2016-12 22 sites Stand-aloneOther conditions: Hemophagocytic Lymphohistiocytosis, Chronic Active Epstein-Barr Virus Infection, Chronic Granulomatous Disease, HIGM-1, Leukocyte Adhesion Deficiency, IPEXView official trial listing → -
Terminated NCT NCT02013167
Blinatumomab Versus Standard of Care Chemotherapy in Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia (ALL)
Not yet reported Amgen 405 participants Est. completion 2017-03-14 117 sitesOther conditions: Relapsed/Refractory B-precursor Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02013817
CHAIROS Study A Study of MabThera/Rituxan (Rituximab) Maintenance Therapy in Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Naive to Chemotherapy
Not yet reported Hoffmann-La Roche 43 participants Est. completion 2012-09-24 8 sites Stand-aloneOther conditions: Lymphocytic Leukemia, ChronicView official trial listing → -
Status unknown NCT NCT02014506
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation in Children and Adolescents
Not yet reported, Not yet reported Asan Medical Center 30 participants Est. completion 2018-12 1 site Stand-aloneOther conditions: Haploidentical Hematopoietic Stem Cell Transplantation, Malignant Disease, Non-malignant DiseaseView official trial listing → -
Status unknown NCT NCT02024308
AML1-ETO Acute Myeloid Leukemia With Fludarabine and Cytarabine Chemotherapy
Not yet reported Changhai Hospital 62 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, AML1-ETO Fusion Protein ExpressionView official trial listing → -
Active, not recruiting NCT NCT02028455
A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD19 for Relapsed/Refractory CD19+ Leukemia
Not yet reported, Not yet reported Seattle Children's Hospital 167 participants Est. completion 2036-07 3 sites Stand-aloneOther conditions: CD19+ Acute LeukemiaView official trial listing → -
Terminated NCT NCT02029638
BMT and High Dose Post-Transplant Cyclophosphamide for Chimerism Induction and Renal Allograft Tolerance
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 4 participants Est. completion 2017-09-06 1 site Stand-aloneOther conditions: Kidney TransplantationView official trial listing → -
Status unknown NCT NCT02034630
Targeted Busulfan, Fludarabine Conditioning Regimen for Hematopoietic Stem Cell Transplantation in GRD
Not yet reported, Not yet reported Seoul National University Hospital 5 participants Est. completion 2023-12 1 siteOther conditions: Genetic Rare DiseaseView official trial listing → -
Completed NCT NCT02039726
(QuANTUM-R): An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia (AML) Subjects Who Are FLT3-ITD Positive
Not yet reported Daiichi Sankyo 367 participants Est. completion 2020-09-08 131 sitesOther conditions: AMLView official trial listing → -
Status unknown NCT NCT02047578
Targeted Busulfan, Fludarabine, Etoposide Conditioning Regimen for HSCT in Childhood and Adolescent ALL.
Not yet reported Seoul National University Hospital 38 participants Est. completion 2023-12 1 siteOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT02049580
Reduced Intensity Conditioning (RIC) Regimen and Post-transplant Cyclophosphamide in Haploidentical Bone Marrow Transplantation in in Patients With Poor Prognosis Lymphomas
Not yet reported Istituto Clinico Humanitas 47 participants Est. completion 2016-11 1 site Stand-aloneOther conditions: LymphomaView official trial listing → -
Withdrawn NCT NCT02053545
Haplo-identical SCT for High Risk (HR) Hematologic Malignancies w/Post-Transplant In-Vivo T-cell Depletion
Not yet reported, Not yet reported Ann & Robert H Lurie Children's Hospital of Chicago Est. completion 2017-05-11 1 site Stand-aloneOther conditions: Leukemia, Lymphoma, MDSView official trial listing → -
Terminated NCT NCT02057770
Allogeneic or Haploidentical Stem Cell Transplant Followed By High-Dose Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported Washington University School of Medicine 25 participants Est. completion 2018-03-23 1 site Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Status unknown NCT NCT02061800
CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant
Not yet reported, Not yet reported Diane George 14 participants Est. completion 2026-07 1 site Stand-aloneOther conditions: Chronic Myeloid Leukemia (CML), Acute Myelogenous Leukemia (AML), Myelodysplastic Syndrome (MDS), Juvenile Myelomonocytic Leukemia (JMML), Acute Lymphoblastic Leukemia (ALL), Lymphoma (Hodgkin's and Non-Hodgkin's)View official trial listing → -
Terminated NCT NCT02062359
T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Melanoma
Not yet reported National Cancer Institute (NCI) 2 participants Est. completion 2016-02 1 site Stand-aloneOther conditions: Metastatic Cancer, Metastatic MelanomaView official trial listing → -
Active, not recruiting NCT NCT02065362
TGF-beta Resistant Cytotoxic T-lymphocytes in Treatment of EBV-positive Nasopharyngeal Carcinoma / RESIST-NPC
Not yet reported Baylor College of Medicine 14 participants Est. completion 2033-02 1 site Stand-aloneOther conditions: EBV-positive Nasopharyngeal CarcinomaView official trial listing → -
Completed NCT NCT02065596
Hematopoietic Stem Cell Transplant for Sickle Cell Disease
Not yet reported Case Comprehensive Cancer Center 4 participants Est. completion 2023-02-17 1 site Stand-aloneOther conditions: Sickle Cell Disease, Sickle Cell Anemia, SCDView official trial listing → -
Terminated NCT NCT02070406
Gene-Modified T Cells, Vaccine Therapy, and Ipilimumab in Treating Patients With Locally Advanced or Metastatic Malignancies
Not yet reported Jonsson Comprehensive Cancer Center 4 participants Est. completion 2018-12-18 1 site Stand-aloneOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT02083250
Fludarabine Phosphate, Clofarabine, and Busulfan With Vorinostat in Treating Patients With Acute Leukemia in Remission or Relapse Undergoing Donor Stem Cell Transplant
Not yet reported M.D. Anderson Cancer Center 70 participants Est. completion 2021-11-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in Remission, Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Myelodysplastic Syndrome, Previously Treated Myelodysplastic Syndrome, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02084563
Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms
Not yet reported Hospital Israelita Albert Einstein 455 participants Est. completion 2016-11 1 siteOther conditions: Acute Myeloid Leukemia, Myeloproliferative Neoplasms, Myelodysplastic Syndromes, Myeloproliferative/Myelodysplastic NeoplasmView official trial listing → -
Completed NCT NCT02085408
Clofarabine or Daunorubicin Hydrochloride and Cytarabine Followed By Decitabine or Observation in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia
Not yet reported ECOG-ACRIN Cancer Research Group 727 participants Est. completion 2022-12-21 269 sitesOther conditions: Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome, Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Erythroleukemia (M6a), Adult Pure Erythroid Leukemia (M6b), Secondary Acute Myeloid Leukemia, Untreated Adult Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02096614
Investigator Initiated Phase 1 Study of TBI-1201
Not yet reported Mie University 18 participants Est. completion 2021-03 1 site Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Status unknown NCT NCT02098512
Immunotherapy Following Reduced Intensity Conditioning and Allogeneic Stem Cell Transplant for Poor Risk CD30+ Hodgkin Lymphoma Patients
Not yet reported, Not yet reported New York Medical College 20 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT02105116
AML Therapy With Irradiated Allogeneic Cells
Not yet reported Rutgers, The State University of New Jersey 6 participants Est. completion 2015-12-16 1 site Stand-aloneOther conditions: Adult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a), Adult Acute Monocytic Leukemia (M5b), Adult Acute Myeloblastic Leukemia With Maturation (M2), Adult Acute Myeloblastic Leukemia Without Maturation (M1), Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Adult Acute Myelomonocytic Leukemia (M4), Adult Erythroleukemia (M6a), Adult Pure Erythroid Leukemia (M6b), Recurrent Adult Acute Myeloid Leukemia, Untreated Adult Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02111850
T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive
Not yet reported, Not yet reported National Cancer Institute (NCI) 21 participants Est. completion 2021-03-24 1 site Stand-aloneOther conditions: Cervical Cancer, Renal Cancer, Urothelial Cancer, Melanoma, Breast CancerView official trial listing → -
Terminated NCT NCT02111863
Immunotherapy Using 41BB Selected Tumor Infiltrating Lymphocytes for Patients With Metastatic Melanoma
Not yet reported National Cancer Institute (NCI) 6 participants Est. completion 2016-07-21 1 site Stand-aloneOther conditions: Melanoma, Skin CancerView official trial listing → -
Completed NCT NCT02118285
Intraperitoneal Natural Killer Cells and INCB024360 for Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Not yet reported Masonic Cancer Center, University of Minnesota 2 participants Est. completion 2015-11-12 1 site Stand-aloneOther conditions: Ovarian Cancer, Fallopian Tube Carcinoma, Primary Peritoneal CarcinomaView official trial listing → -
Withdrawn NCT NCT02118311
Treg Cells for AGVHD in Non-myeloablative UCB Transplant
Not yet reported Masonic Cancer Center, University of Minnesota Est. completion 2018-09 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Withdrawn NCT NCT02127905
Unrelated HSCT in Patients With Fanconi Anemia
Not yet reported Neena Kapoor, M.D. Est. completion 2016-03 1 siteOther conditions: Fanconi AnemiaView official trial listing → -
Completed NCT NCT02128945
Dosimetry and Biodistribution of [18F]-Fludarabine in Lymphoid Malignancies
Not yet reported University Hospital, Caen 10 participants Est. completion 2016-05 1 site Stand-aloneOther conditions: Untreated B-Chronic Lymphocytic Leukemia or Diffuse Large B Cells Lymphoma PatientsView official trial listing → -
Completed NCT NCT02129582
Targeted Marrow Irradiation, Fludarabine Phosphate, and Busulfan Before Donor Progenitor Cell Transplant in Treating Patients With Hematologic Malignancies
Not yet reported Case Comprehensive Cancer Center 14 participants Est. completion 2020-03-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Hematologic Malignancies, Acute Lymphocytic Leukemia, Non Hodgkin Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Myelodysplastic Syndrome, Chronic Lymphocytic Leukemia, Chronic Myeloid Leukemia, Myelofibrosis, Myeloproliferative SyndromeView official trial listing → -
Terminated NCT NCT02145039
Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases
Not yet reported Masonic Cancer Center, University of Minnesota 2 participants Est. completion 2019-01 1 site Stand-aloneOther conditions: Acute Leukemias, Burkitt's Lymphoma, Chronic Myelogenous LeukemiaView official trial listing → -
Active, not recruiting NCT NCT02153580
Cellular Immunotherapy Following Chemotherapy in Treating Patients With Recurrent Non-Hodgkin Lymphomas, Chronic Lymphocytic Leukemia, or B-Cell Prolymphocytic Leukemia
Not yet reported City of Hope Medical Center 37 participants Est. completion 2026-09-02 1 site Stand-aloneOther conditions: B-Cell Lymphoma, Unclassifiable, With Features Intermediate Between Diffuse Large B-Cell Lymphoma and Classic Hodgkin Lymphoma, B-Cell Prolymphocytic Leukemia, High Grade B-Cell Lymphoma, Not Otherwise Specified, Post-Transplant Lymphoproliferative Disorder, Recurrent Adult Burkitt Lymphoma, Recurrent Chronic Lymphocytic Leukemia, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Follicular Lymphoma, Recurrent Hairy Cell Leukemia, Recurrent Lymphoplasmacytic Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Recurrent Small Lymphocytic LymphomaView official trial listing → -
Terminated NCT NCT02153905
T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-A*01 Positive
Not yet reported, Not yet reported National Cancer Institute (NCI) 3 participants Est. completion 2018-09-10 1 site Stand-aloneOther conditions: Breast Cancer, Cervical Cancer, Renal Cancer, Melanoma, Bladder CancerView official trial listing → -
Status unknown NCT NCT02156726
Observational Study of Low Dose FCR in Elderly/Comorbid CLL/SLL: The Q-lite Project
Czech CLL Study Group 200 participants Est. completion 2015-07 7 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT02158091
A Phase 1b/2 Study of IPI-145 Plus FCR in Previously Untreated, Younger Patients With CLL
Not yet reported, Not yet reported Dana-Farber Cancer Institute 32 participants Est. completion 2026-07 2 sites Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT02159495
Genetically Modified T-cell Immunotherapy in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia and Persistent/Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm
Not yet reported City of Hope Medical Center 31 participants Est. completion 2027-07-14 1 site Stand-aloneOther conditions: Adult Acute Myeloid Leukemia in Remission, Acute Biphenotypic Leukemia, Early Relapse of Acute Myeloid Leukemia, Late Relapse of Acute Myeloid Leukemia, Recurrent Adult Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Blastic Plasmacytoid Dendritic Cell Neoplasm, Acute Myeloid Leukemia, Adult Acute Lymphoblastic Leukemia, Interleukin-3 Receptor Subunit Alpha Positive, Minimal Residual Disease, Refractory Acute Myeloid Leukemia, Untreated Adult Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02162420
Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia
Not yet reported Masonic Cancer Center, University of Minnesota 61 participants Est. completion 2025-03-11 1 site Stand-aloneOther conditions: Dyskeratosis Congenita, Aplastic AnemiaView official trial listing → -
Completed NCT NCT02165007
Haploidentical Hematopoietic Stem Cell Transplantation
Not yet reported Catherine Bollard 7 participants Est. completion 2024-10 1 site Stand-aloneOther conditions: Sickle Cell-thalassemia Disease, ThalassemiaView official trial listing → -
Completed NCT NCT02167958
Nonmyeloablative Hematopoietic Cell Transplantation (HCT) for Patients With Hematologic Malignancies Using Related, HLA-Haploidentical Donors: A Pilot Trial of Peripheral Blood Stem Cells (PBSC) as the Donor Source
Not yet reported Rafic Farah, MD 28 participants Est. completion 2019-09-21 1 site Stand-aloneOther conditions: Leukemia, MDS, Myelofibrosis, LymphomaView official trial listing → -
Completed NCT NCT02169791
Nonmyeloablative Haploidentical Transplant Followed by MLN9708
Not yet reported Northside Hospital, Inc. 29 participants Est. completion 2020-07-28 1 site Stand-aloneOther conditions: Acute Leukemia, Chronic Leukemia, Myelodysplastic Syndrome, Lymphomas, Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT02171104
MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis
Not yet reported Masonic Cancer Center, University of Minnesota 149 participants Est. completion 2029-07-14 1 site Stand-aloneObstructive sleep apnea Other conditions: Mucopolysaccharidosis Disorders, Hurler Syndrome, Hunter Syndrome, Maroteaux Lamy Syndrome, Sly Syndrome, Alpha-Mannosidosis, Fucosidosis, Glycoprotein Metabolic Disorders, Sphingolipidoses, Recessive Leukodystrophies, Globoid Cell Leukodystrophy, Metachromatic Leukodystrophy, Niemann-Pick B, Niemann-Pick C Subtype 2, Sphingomyelin Deficiency, Peroxisomal Disorders, Adrenoleukodystrophy With Cerebral Involvement, Zellweger Syndrome, Neonatal Adrenoleukodystrophy, Infantile Refsum Disease, Acyl-CoA Oxidase Deficiency, D-Bifunctional Enzyme Deficiency, Multifunctional Enzyme Deficiency, Alpha-methylacyl-CoA Racmase Deficiency, Mitochondrial Neurogastrointestingal Encephalopathy, Severe Osteopetrosis, Hereditary Leukoencephalopathy With Axonal Spheroids (HDLS; CSF1R Mutation), Inherited Metabolic DisordersView official trial listing → -
Status unknown NCT NCT02178683
Tacrolimus and Mycophenolate Mofetil as Post-Grafting Immunosuppression
Not yet reported Colorado Blood Cancer Institute 50 participants Est. completion 2018-12 1 siteOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT02181478
Intra-Osseous Co-Transplant of UCB and hMSC
Not yet reported Case Comprehensive Cancer Center 6 participants Est. completion 2020-02-07 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Myelodysplastic Syndromes, Myelofibrosis, Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Hodgkin Lymphoma, Refractory Hodgkin Lymphoma, Relapsed Chronic Lymphocytic Leukemia, Refractory Chronic Lymphocytic Leukemia, Lymphoid Malignancies, Chronic Myelogenous LeukemiaView official trial listing → -
Withdrawn NCT NCT02194374
Autologous ROR1R-CAR-T Cells for Chronic Lymphocytic Leukemia (CLL)
Not yet reported M.D. Anderson Cancer Center Est. completion 2017-06 Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT02199041
Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen
Not yet reported St. Jude Children's Research Hospital 24 participants Est. completion 2017-05-23 1 site Stand-aloneOther conditions: Hematological MalignanciesView official trial listing → -
Status unknown NCT NCT02199301
Tolerance Induction in Living Donor Kidney Transplantation With Hematopoietic Stem Cell Transplantation
Not yet reported Samsung Medical Center 6 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: End Stage Renal DiseaseView official trial listing → -
Completed NCT NCT02212561
Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome
Not yet reported St. Jude Children's Research Hospital 19 participants Est. completion 2015-12 6 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Myelodysplastic Syndrome (MDS), Mixed Phenotype Acute Leukemia (MPAL)View official trial listing → -
Completed NCT NCT02215967
Study of T Cells Targeting B-Cell Maturation Antigen for Previously Treated Multiple Myeloma
Not yet reported National Cancer Institute (NCI) 30 participants Est. completion 2019-08-15 1 site Stand-aloneOther conditions: Myeloma, Plasma-Cell, Myeloma-MultipleView official trial listing → -
Completed NCT NCT02220985
Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD
Not yet reported Fred Hutchinson Cancer Center 84 participants Est. completion 2025-05-01 2 sites Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Leukemia of Ambiguous Lineage, Acute Undifferentiated Leukemia, Allogeneic Hematopoietic Stem Cell Transplant Recipient, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Blastic Plasmacytoid Dendritic Cell Neoplasm, Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Donor, Lymphoblastic Lymphoma, Myelodysplastic Syndrome With Excess Blasts, Myelodysplastic Syndrome With Excess Blasts-1, Myelodysplastic Syndrome With Excess Blasts-2, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Myeloid Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia in RemissionView official trial listing → -
Completed NCT NCT02224872
Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 18 participants Est. completion 2021-12 2 sites Stand-aloneOther conditions: Severe Aplastic Anemia, Bone Marrow Failure SyndromesView official trial listing → -
Terminated NCT NCT02229266
Randomised Controlled Phase-2 Trial to Determine the Efficacy of Adoptive Immunotherapy With NK Cells in High-risk AML
Not yet reported Technische Universität Dresden 1 participants Est. completion 2017-04-22 3 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02248597
Donor Stem Cell Transplant Followed by Cyclophosphamide in Treating Patients With Hematological Diseases
Not yet reported Wake Forest University Health Sciences 27 participants Est. completion 2023-01-18 1 site Stand-aloneOther conditions: Graft Versus Host Disease, Hematopoietic/Lymphoid CancerView official trial listing → -
Active, not recruiting NCT NCT02250937
Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome
Not yet reported M.D. Anderson Cancer Center 116 participants Est. completion 2027-10-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT02251548
A Phase II Study of Ibrutinib Plus FCR in Previously Untreated, Younger Patients With Chronic Lymphocytic Leukemia
Not yet reported Dana-Farber Cancer Institute 85 participants Est. completion 2027-01 9 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, LeukemiaView official trial listing → -
Completed NCT NCT02251821
JAK Inhibitor Before Donor Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis
Not yet reported Fred Hutchinson Cancer Center 61 participants Est. completion 2026-01-22 1 site Stand-aloneOther conditions: Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Completed NCT NCT02252107
10-day Decitabine, Fludarabine and 2 Gray TBI as Conditioning Strategy for Poor and Very Poor Risk AML in CR1
Not yet reported Radboud University Medical Center 46 participants Est. completion 2019-05 3 sitesOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Terminated NCT NCT02259348
Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation
Not yet reported St. Jude Children's Research Hospital 12 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Myeloid Sarcoma, Chronic Myelogenous Leukemia (CML), Juvenile Myelomonocytic Leukemia (JMML), Myelodysplastic Syndrome (MDS), Non-Hodgkin Lymphoma (NHL)View official trial listing → -
Status unknown NCT NCT02272478
Trial to Test the Effects of Adding 1 of 2 New Treatment Agents to Commonly Used Chemotherapy Combinations
Not yet reported, Not yet reported Cardiff University 1600 participants Est. completion 2022-02 87 sitesOther conditions: Acute Myeloid Leukaemia, Myelodysplastic SyndromeView official trial listing → -
Withdrawn NCT NCT02274506
Infusion of Allogeneic, 3rd Party CD19-specific T Cells
Not yet reported M.D. Anderson Cancer Center Est. completion 2014-10-20 Stand-aloneOther conditions: Blood And Marrow Transplantation, Leukemia, LymphomaView official trial listing → -
Status unknown NCT NCT02275663
Azacytidine Plus FLAG for Relapsed or Refractory AML
Not yet reported King Fahad Medical City 37 participants Est. completion 2018-10 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02278887
Study Comparing TIL to Standard Ipilimumab in Patients With Metastatic Melanoma
Not yet reported The Netherlands Cancer Institute 168 participants Est. completion 2023-12-31 2 sites Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT02280525
Cord Blood Natural Killer (NK) Cells in Leukemia/Lymphoma
Not yet reported M.D. Anderson Cancer Center 8 participants Est. completion 2019-07-09 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT02280811
T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated Cancers
Not yet reported, Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2016-06-28 1 site Stand-aloneOther conditions: Vaginal Cancer, Cervical Cancer, Anal Cancer, Penile Cancer, Oropharyngeal CancerView official trial listing → -
Terminated NCT NCT02282904
Haploidentical Transplant for People With Chronic Granulomatous Disease Using Post Transplant Cyclophosphamide
Not yet reported, Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 7 participants Est. completion 2019-12-10 1 site Stand-aloneOther conditions: Chronic Granulomatous DiseaseView official trial listing → -
Completed NCT NCT02294552
Post-transplantation Cyclophosphamide as GVHD Prophylaxis After HSCT
Not yet reported Ivan S Moiseev 200 participants Est. completion 2017-11 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Lymphoma, Myelodysplastic Syndromes, Chronic Lymphocytic Leukemia, Immune System DiseasesView official trial listing → -
Terminated NCT NCT02310997
Myloablative Cord Blood Transplant in Haematological Malignancies (MAC UCBT)
Not yet reported University College, London 11 participants Est. completion 2015-05 12 sites Stand-aloneOther conditions: Leukaemia, Lymphoma, Other Haematological DiseasesView official trial listing → -
Completed NCT NCT02319135
Azacytidine (Vidaza®) Versus Fludarabine and Cytarabine (Fluga Scheme) in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia
Not yet reported PETHEMA Foundation 289 participants Est. completion 2019-10-28 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT02328950
A 5 Day Course of Fludarabine and Cytarabine Followed by Full Intensity Allogeneic Stem Cell Transplantation (FA5-Bucy) in Treating Patients With High-risk, Recurrent or Refractory Acute Leukemia and Advanced Myelodysplastic Syndrome
Fujian Medical University 50 participants Est. completion 2017-12 1 siteOther conditions: Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Completed NCT NCT02333058
Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies
Not yet reported medac GmbH 70 participants Est. completion 2019-09-30 24 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukaemias (ALL), Acute Myeloid Leukaemias (AML), Myelodysplastic Syndromes (MDS), Juvenile Myelomonocytic Leukaemias (JMML)View official trial listing → -
Suspended NCT NCT02333162
Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant
Not yet reported University of Chicago 30 participants Est. completion 2028-12-01 1 site Stand-aloneOther conditions: Previously Treated Myelodysplastic Syndrome, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Hematologic MalignancyView official trial listing → -
Status unknown NCT NCT02333838
Reduced Toxicity Conditioning Prior to Unrelated Cord Cell Transplantation for High Risk Myeloid Malignancies
Not yet reported Assistance Publique - Hôpitaux de Paris 31 participants Est. completion 2019-05 1 site Stand-aloneOther conditions: Leukemia, MyeloidView official trial listing → -
Completed NCT NCT02348216
Study Evaluating the Safety and Efficacy of KTE-C19 in Adult Participants With Refractory Aggressive Non-Hodgkin Lymphoma
Not yet reported, Not yet reported Kite, A Gilead Company 307 participants Est. completion 2023-07-27 36 sites Stand-aloneOther conditions: Refractory Diffuse Large B Cell Lymphoma (DLBCL), Relapsed Diffuse Large B-Cell Lymphoma, Transformed Follicular Lymphoma (TFL), Primary Mediastinal B-cell Lymphoma (PMBCL), High Grade B-cell Lymphoma (HGBCL)View official trial listing → -
Completed NCT NCT02354690
Vemurafenib and TIL Therapy for Metastatic Melanoma
Not yet reported, Not yet reported Inge Marie Svane 13 participants Est. completion 2018-12-31 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT02356159
Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation
Not yet reported, Not yet reported National Cancer Institute (NCI) 34 participants Est. completion 2025-03-25 2 sites Stand-aloneOther conditions: Myelodysplastic Syndromes, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Acute Leukemia, Multiple MyelomaView official trial listing → -
Terminated NCT NCT02360111
GVHD Prophylaxis With Post Transplant Cyclophosphamide for Patients With Renal Insufficiency Undergoing a Conventional 8/8 HLA-matched Related or Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplant
Not yet reported Memorial Sloan Kettering Cancer Center 3 participants Est. completion 2017-09 1 site Stand-aloneOther conditions: Leukemia, Myelodysplastic Syndrome, Non-Hodgkin's LymphomaView official trial listing → -
Status unknown NCT NCT02366546
Investigator Initiated Phase 1 Study of TBI-1301
Not yet reported Mie University 9 participants 1 site Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Terminated NCT NCT02375984
A Study Using Tumor-Reactive Autologous Tumor Infiltrating Lymphocytes (TIL) in Metastatic Melanomas
Not yet reported Saint John's Cancer Institute 1 participants Est. completion 2017-06-01 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT02379195
Peginterferon and TIL Therapy for Metastatic Melanoma
Not yet reported, Not yet reported Inge Marie Svane 12 participants Est. completion 2018-10 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT02379520
HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA
Not yet reported Baylor College of Medicine 35 participants Est. completion 2026-01 1 site Stand-aloneOther conditions: Human Papillomavirus-Related Carcinoma, Human Papillomavirus Positive Oropharyngeal Carcinoma, Human Papillomavirus Positive Cervical Carcinoma, Human Papillomavirus Positive Anal Carcinoma, Human Papillomavirus Positive Vulvar Carcinoma, Human Papillomavirus Positive Penile CarcinomaView official trial listing → -
Status unknown NCT NCT02385955
Phase II Study of Myeloablative Double Unit Umbilical Cord Blood Transplantation in Adult Patients
Not yet reported Seoul National University Hospital 39 participants Est. completion 2019-04 Stand-aloneOther conditions: Hematologic MalignancyView official trial listing → -
Status unknown NCT NCT02386332
A Randomized Multicenter Study to Compare Two Types of Transplant in Adult Patients With Hematologic Malignancies
Instituto de Investigacion Sanitaria La Fe 206 participants Est. completion 2020-03Other conditions: Hematologic MalignanciesView official trial listing → -
Withdrawn NCT NCT02390739
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing Human Thyroglobulin to People With Thyroglobulin Expressing Thyroid Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) Est. completion 2017-03-22 Stand-aloneOther conditions: Metastatic Thyroid CancerView official trial listing → -
Completed NCT NCT02395822
MT2014-25: Haplo NK With SQ IL-15 in Adult Relapsed or Refractory AML Patients
Not yet reported Masonic Cancer Center, University of Minnesota 17 participants Est. completion 2016-12-01 1 site Stand-aloneOther conditions: Acute Myelogenous LeukemiaView official trial listing → -
Completed NCT NCT02400281
Study of Crenolanib Combined With Chemotherapy in FLT3-mutated Acute Myeloid Leukemia Patients
Not yet reported, Not yet reported Arog Pharmaceuticals, Inc. 28 participants Est. completion 2020-07-15 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT02409576
Pilot Study of Expanded , Activated Haploidentical Natural Killer Cell Infusions for Sarcomas
Not yet reported, Not yet reported National University Hospital, Singapore 20 participants Est. completion 2020-09 1 site Stand-aloneObstructive sleep apnea Other conditions: Ewing SarcomaView official trial listing → -
Terminated NCT NCT02410551
Pacritinib Before Transplant for Myeloproliferative Neoplasms (MPN)
Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2017-01-20 1 site Stand-aloneOther conditions: Myeloproliferative DiseasesView official trial listing → -
Terminated NCT NCT02412475
Epigenetic Reprogramming in Relapse AML
Not yet reported Michael Burke 3 participants Est. completion 2017-06-21 2 sites Stand-aloneOther conditions: Leukemia, Acute MyeloidView official trial listing → -
Completed NCT NCT02414945
TILs & Low-Dose IL-2 Therapy Following Cyclophosphamide and Fludarabine in Pleural Mesothelioma Patients
Not yet reported, Not yet reported University Health Network, Toronto 9 participants Est. completion 2020-10 1 site Stand-aloneOther conditions: Pleural MesotheliomaView official trial listing → -
Completed NCT NCT02421939
A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation
Not yet reported Astellas Pharma Global Development, Inc. 371 participants Est. completion 2025-02-25 126 sitesOther conditions: Leukemia, Acute Myeloid (AML)View official trial listing → -
Completed NCT NCT02423915
Fucosylated T Cells for Graft Versus Host Disease (GVHD) Prevention
Not yet reported M.D. Anderson Cancer Center 5 participants Est. completion 2020-10-06 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT02428517
Allogeneic Hematopoietic Cell Transplantation for Adult Acute Lymphoblastic Leukemia (2015)
Asan Medical Center 20 participants Est. completion 2016-07 4 sitesOther conditions: Precursor Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Completed NCT NCT02431988
Evaluation of CAR19 T-cells as an Optimal Bridge to Allogeneic Transplantation
Not yet reported University College, London 10 participants Est. completion 2022-03-21 1 site Stand-aloneOther conditions: Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT02435901
HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity
Not yet reported, Not yet reported Northwell Health 29 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Sickle Cell Disease, Beta Thalassemia-MajorView official trial listing → -
Withdrawn NCT NCT02439788
3RD GENERATION GD2 SPECIFIC CHIMERIC ANTIGEN RECEPTOR TRANSDUCED AUTOLOGOUS NATURAL KILLER T-CELLS FOR NEUROBLASTOMA
Not yet reported Baylor College of Medicine Est. completion 2030-10 1 site Stand-aloneOther conditions: NeuroblastomaView official trial listing → -
Completed NCT NCT02440464
Allogeneic Hematopoietic Stem Cell Transplantation With Ixazomib for High Risk Multiple Myeloma (BMT CTN 1302)
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 57 participants Est. completion 2020-10-01 15 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT02441803
Allogeneic Hematopoietic Stem Cell Transplantation (AlloSCT) Initial Salvage Therapy for Induction Failure Acute Myeloid Leukemia (AML)
Not yet reported M.D. Anderson Cancer Center 11 participants Est. completion 2021-09-22 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT02445248
Study of Efficacy and Safety of CTL019 in Adult DLBCL Patients
Not yet reported Novartis Pharmaceuticals 115 participants Est. completion 2022-12-22 26 sites Stand-aloneOther conditions: Diffuse Large B-cell Lymphoma (DLBCL)View official trial listing → -
Withdrawn NCT NCT02447055
Allogeneic Stem Cell Transplantation for Patients With Multiple Myeloma
Not yet reported Washington University School of Medicine Est. completion 2016-06 Stand-aloneOther conditions: Multiple Myeloma, Myeloma-MultipleView official trial listing → -
Status unknown NCT NCT02456350
Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell Malignancies
Not yet reported Shenzhen Second People's Hospital 36 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Acute Lymphocytic Leukemia, LymphomaView official trial listing → -
Status unknown NCT NCT02457650
T Cell Receptor-transduced T Cells Targeting NY-ESO-1 for Treatment of Patients With NY-ESO-1- Expressing Malignancies
Not yet reported Shenzhen Second People's Hospital 36 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Bladder Carcinoma, Breast Cancer, Esophagus Carcinoma, Lung Cancer, Melanoma, Multiple Myeloma, Neuroblastoma, Ovarian Cancer, Synovial Sarcoma, Other Metastatic Solid CancersView official trial listing → -
Completed NCT NCT02461121
HLA-mismatched MST vs HLA-matched NST for AML in Intermediate-risk
Not yet reported The Affiliated Hospital of the Chinese Academy of Military Medical Sciences 156 participants Est. completion 2013-05 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02461316
Rituximab in Combination With Fludarabine and Cyclophosphamide in Patients With Chronic Lymphocytic Leukemia
Hoffmann-La Roche 22 participants Est. completion 2011-12 3 sitesOther conditions: Lymphocytic Leukemia, Chronic, Chronic Lymphocytic Leukemia, CancerView official trial listing → -
Completed NCT NCT02472392
Study To Examine Toxicity Of Allogeneic Stem Cell Transplantation For Relapsed Or Therapy Refractory Ewings Sarcoma
Not yet reported University of Louisville 10 participants Est. completion 2016-12 1 siteOther conditions: EWINGS SARCOMAView official trial listing → -
Completed NCT NCT02482090
TIL Therapy for Metastatic Ovarian Cancer
Not yet reported Inge Marie Svane 6 participants Est. completion 2017-04 1 site Stand-aloneOther conditions: Metastatic Ovarian CancerView official trial listing → -
Completed NCT NCT02483325
Study Evaluating the Efficacy of Allogeneic Transplant Conditioning With Adaptive Dose Busulfan Intravenous (Busilvex®) in Patients at High Risk of Carrying Blood Diseases
Not yet reported Institut Paoli-Calmettes 33 participants Est. completion 2020-03 1 siteOther conditions: Hematological DiseasesView official trial listing → -
Withdrawn NCT NCT02489266
In Vivo Persistence of Adoptively-Transferred TIL Cultured With Akti in People With Metastatic Melanoma
Not yet reported National Cancer Institute (NCI) Est. completion 2016-06-29 Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT02497404
Azacytidine Prior to in Vivo T-cell Depleted Allo Stem Cell Transplant for Patients With Myeloid Malignancies in CR
Not yet reported Weill Medical College of Cornell University 40 participants Est. completion 2021-06-17 1 site Stand-aloneOther conditions: Leukemia, Erythroblastic, Acute, Myelodysplastic SyndromesView official trial listing → -
Active, not recruiting NCT NCT02498912
Cyclophosphamide Followed by Intravenous and Intraperitoneal Infusion of Autologous T Cells Genetically Engineered to Secrete IL-12 and to Target the MUC16ecto Antigen in Patients With Recurrent MUC16ecto+ Solid Tumors
Not yet reported Memorial Sloan Kettering Cancer Center 18 participants Est. completion 2027-08 1 site Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT02500550
Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor
Not yet reported Kiadis Pharma 15 participants Est. completion 2018-12-17 11 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT02500576
Pembrolizumab, Standard Chemotherapy, Tumor Infiltrating Lymphocytes, and High- or Low-Dose Aldesleukin in Treating Patients With Metastatic Melanoma
Not yet reported M.D. Anderson Cancer Center 18 participants Est. completion 2022-10-12 1 site Stand-aloneOther conditions: Metastatic Melanoma, Stage IIIB Cutaneous Melanoma AJCC v7, Stage IIIC Cutaneous Melanoma AJCC v7, Stage IV Cutaneous Melanoma AJCC v6 and v7View official trial listing → -
Completed NCT NCT02504047
Use of Haploidentical Related Donors for Patients Without Matched Sibling, Unrelated Donor or Cord Blood Units
Not yet reported University of Calgary 40 participants Est. completion 2019-02 5 sites Stand-aloneOther conditions: Hematologic NeoplasmsView official trial listing → -
Status unknown NCT NCT02507479
Thiotepa-based Conditioning for Allogeneic Stem-cell Transplantation (SCT) in Lymphoid Malignancies
Not yet reported Sheba Medical Center 24 participants Est. completion 2019-07 2 sitesOther conditions: Non Hodgkin Lymphoma, Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Multiple MyelomaView official trial listing → -
Completed NCT NCT02512497
Romidepsin Maintenance After Allogeneic Stem Cell Transplantation
Not yet reported Ohio State University Comprehensive Cancer Center 23 participants Est. completion 2025-06-18 1 site Stand-aloneOther conditions: Cutaneous T-cell Lymphoma, T-Prolymphocytic Leukemia, T-Large Granulocytic Leukemia, T-Lymphoblastic Leukemia/Lymphoma, Peripheral T-Cell LymphomaView official trial listing → -
Terminated NCT NCT02512679
Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells
Not yet reported Children's Hospital Los Angeles 20 participants Est. completion 2014-02Other conditions: Stem Cell Transplantation, Bone Marrow Transplantation, Peripheral Blood Stem Cell Transplantation, Allogeneic Transplantation, Genetic Diseases, Thalassemia, Pediatrics, Diamond-Blackfan Anemia, Combined Immune Deficiency, Wiskott-Aldrich Syndrome, Chronic Granulomatous Disease, X-linked Lymphoproliferative Disease, Metabolic DiseasesView official trial listing → -
Active, not recruiting NCT NCT02514083
A Phase II Study Using Ibrutinib and Short-Course Fludarabine in Treatment-Naive CLL
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 29 participants Est. completion 2034-10-23 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT02520895
Immunological Repertoire in Patients With Lymphoma and Chronic Lymphocytic Leukemia
Hospices Civils de Lyon 98 participants Est. completion 2013-10 1 siteOther conditions: LYMPHOMAView official trial listing → -
Status unknown NCT NCT02520908
Benefit of Allogeneic Haematopoietic Stem Cells in Cutaneous T-cell Lymphomas Epidermotropic With Advanced Stage and Poor Prognosis
Assistance Publique - Hôpitaux de Paris 98 participants Est. completion 2024-11-19 1 siteOther conditions: Epidermotropic T-cell LymphomasView official trial listing → -
Withdrawn NCT NCT02528877
Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis
Not yet reported City of Hope Medical Center 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia in Remission, Primary Myelofibrosis, Primary Myelofibrosis, Prefibrotic Stage, Secondary Acute Myeloid Leukemia, Secondary MyelofibrosisView official trial listing → -
Completed NCT NCT02529813
CD19-Specific T-cells in Treating Patients With Advanced Lymphoid Malignancies
Not yet reported M.D. Anderson Cancer Center 26 participants Est. completion 2021-11-08 1 site Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia, Blasts 5 Percent or More of Bone Marrow Nucleated Cells, CD19 Positive, Minimal Residual Disease, Non-Hodgkin Lymphoma, Small Lymphocytic Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage IV Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT02529839
Safety and Efficacy of an Immunoablative Nonmyeloablative Conditioning Protocol for Autologous Bone Marrow Transplantation (BMT) in Patients With Multiple Sclerosis (MS)
Not yet reported Hadassah Medical Organization 20 participants Est. completion 2017-10 Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Completed NCT NCT02533401
A Study of Rituximab (MabThera) in Participants With Chronic Lymphocytic Leukemia (CLL)
Not yet reported Hoffmann-La Roche 34 participants Est. completion 2014-12 9 sites Stand-aloneOther conditions: Lymphocytic Leukemia, ChronicView official trial listing → -
Terminated NCT NCT02535364
Study Evaluating the Efficacy and Safety of JCAR015 in Adult B-cell Acute Lymphoblastic Leukemia (B-ALL)
Not yet reported Juno Therapeutics, a Subsidiary of Celgene 82 participants Est. completion 2017-09-01 18 sites Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Withdrawn NCT NCT02548468
Reduced Intensity Conditioning Before Partially Matched Donor Stem Cell Transplant in Treating Patients With Advanced Cutaneous T Cell Lymphoma
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University Est. completion 2017-03-16 Stand-aloneOther conditions: Cutaneous T-Cell Non-Hodgkin Lymphoma, Recurrent Mycosis Fungoides and Sezary Syndrome, Stage IIB Mycosis Fungoides and Sezary Syndrome, Stage IIIA Mycosis Fungoides and Sezary Syndrome, Stage IIIB Mycosis Fungoides and Sezary Syndrome, Stage IVA Mycosis Fungoides and Sezary Syndrome, Stage IVB Mycosis Fungoides and Sezary SyndromeView official trial listing → -
Completed NCT NCT02551718
High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia
Not yet reported University of Washington 34 participants Est. completion 2021-05-13 1 site Stand-aloneOther conditions: Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Acute Leukemia of Ambiguous LineageView official trial listing → -
Completed NCT NCT02556931
Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malignancies
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 117 participants Est. completion 2021-04 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, Small Lymphocytic Lymphoma, Chronic Lymphocytic Leukemia, Prolymphocytic Leukemia, Chronic Myeloid Leukemia, Chronic Myeloproliferative Disorders, Multiple Myeloma, Plasma Cell Neoplasm, Plasma Cell Dyscrasia, Myelofibrosis, Polycythemia Vera, Essential Thrombocythemia, Plasma Cell LeukemiaView official trial listing → -
Completed NCT NCT02566304
Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 35 participants Est. completion 2024-02-13 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Myeloid Leukemia in Remission, Aplastic Anemia, Chronic Myelomonocytic Leukemia, Hodgkin Lymphoma, Indolent Non-Hodgkin Lymphoma, Malignant Neoplasm, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Plasma Cell Myeloma, Refractory Anemia, Refractory Anemia With Excess Blasts, Refractory Anemia With Ring Sideroblasts, Refractory Cytopenia With Multilineage Dysplasia, Refractory Cytopenia With Multilineage Dysplasia and Ring SideroblastsView official trial listing → -
Withdrawn NCT NCT02577094
Testing a Reduced Conditioning Regimen FB2A2 Preceded by a Fractionated Radio-immunotherapy (RIT) With 90Y-Epratuzumab Before Allogeneic Stem Cell Transplantation for Patients With Lymphocyte B CD22 Positive Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported Nantes University Hospital Est. completion 2017-01Other conditions: Lymphocyte B CD22 Positive Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02581007
Reduced Intensity Conditioning Transplant Using Haploidentical Donors
Not yet reported Northside Hospital, Inc. 25 participants Est. completion 2020-12-28 1 site Stand-aloneOther conditions: Chronic Myelogenous Leukemia, Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Acute Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, Hodgkin's Lymphoma, Non-Hodgkin's Lymphoma, Myelofibrosis, CMML, Multiple MyelomaView official trial listing → -
Completed NCT NCT02582775
MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCs
Not yet reported Masonic Cancer Center, University of Minnesota 17 participants Est. completion 2023-07-26 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT02588612
Letetresgene Autoleucel Engineered T Cells in NY-ESO -1 Positive Advanced Non-Small Cell Lung Cancer (NSCLC)
Not yet reported GlaxoSmithKline 10 participants Est. completion 2020-08-10 3 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Completed NCT NCT02601313
Study of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 1 and Cohort 2)
Not yet reported Kite, A Gilead Company 105 participants Est. completion 2023-09-22 32 sites Stand-aloneOther conditions: Relapsed/Refractory Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT02614066
A Study Evaluating the Safety and Efficacy of Brexucabtagene Autoleucel (KTE-X19) in Adult Subjects With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (ZUMA-3)
Not yet reported, Not yet reported Kite, A Gilead Company 125 participants Est. completion 2023-11-03 33 sites Stand-aloneOther conditions: Relapsed/Refractory B-precursor Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT02614560
A Study of Vadastuximab Talirine Given Prior to or After Allogeneic Hematopoietic Stem Cell Transplant in AML Patients
Not yet reported, Not yet reported Seagen Inc. 14 participants Est. completion 2017-09-14 11 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02626338
Pilot Study of Crenolanib Combined With Standard Salvage Chemotherapy in Subjects With R/R AML
Not yet reported, Not yet reported Arog Pharmaceuticals, Inc. 16 participants Est. completion 2018-02 4 sites Stand-aloneOther conditions: Relapsed/Refractory Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT02626715
Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS
Not yet reported Randy Windreich 21 participants Est. completion 2023-04-12 1 siteOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Hematopoietic Stem Cell Transplant (HSCT)View official trial listing → -
Terminated NCT NCT02627573
Trial of GVHD Prophylasxis With PTCy or Thymoglobulin in Unrelated SCT
Not yet reported St. Petersburg State Pavlov Medical University 32 participants Est. completion 2019-04-03 1 site Stand-aloneOther conditions: Leukemia, Chronic Myeloid, Myelodysplastic Syndromes, Leukemia, Myeloid, Chronic, Atypical, BCR-ABL NegativeView official trial listing → -
Active, not recruiting NCT NCT02629809
Ibrutinib, Fludarabine Phosphate, Cyclophosphamide, and Obinutuzumab in Treating Patients With Chronic Lymphocytic Leukemia
Not yet reported M.D. Anderson Cancer Center 81 participants Est. completion 2028-03-31 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Status unknown NCT NCT02638428
Genomics-Based Target Therapy for Children With Relapsed or Refractory Malignancy
Not yet reported Samsung Medical Center 90 participants Est. completion 2023-12 1 site Stand-aloneOther conditions: Relapsed Pediatric Solid Tumor, Refractory Pediatric Solid Tumor, Relapsed Pediatric AML, Refractory Pediatric AMLView official trial listing → -
Completed NCT NCT02642965
Liposome-encapsulated Daunorubicin-Cytarabine, Fludarabine Phosphate, Cytarabine, and Filgrastim in Treating Younger Patients With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported Children's Oncology Group 38 participants Est. completion 2023-06-30 73 sites Stand-aloneOther conditions: Acute Myeloid Leukemia Post Cytotoxic Therapy, Recurrent Childhood Acute Myeloid Leukemia, Secondary Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02649764
Prexasertib (LY2606368), Cytarabine, and Fludarabine in Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome
Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2022-07-12 1 site Stand-aloneOther conditions: Chronic Myelomonocytic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent High Risk Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory High Risk Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT02652455
Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 11 participants Est. completion 2020-08-30 1 site Stand-aloneOther conditions: Melanoma (Skin), Skin CancerView official trial listing → -
Terminated NCT NCT02653196
A Multi-Institutional Pilot Study of Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Malignant Neuro-Epithelial and Other Solid Tumors
Not yet reported Montefiore Medical Center 1 participants Est. completion 2017-08 1 site Stand-aloneOther conditions: Neuroepithelial Tumor, Solid Tumor, Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT02659943
T Cells Expressing a Fully-human AntiCD19 Chimeric Antigen Receptor for Treating B-cell Malignancies
Not yet reported National Cancer Institute (NCI) 27 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: Lymphoma, B-Cell, Lymphoma, Non-hodgkinsView official trial listing → -
Completed NCT NCT02660281
URMC Related Haplo-identical Donor BMT
Not yet reported University of Rochester 74 participants Est. completion 2021-01-07 1 siteOther conditions: Hematological Disease, Immune Deficiencies, Solid Tumors, Myelofibrosis, Multiple Myeloma, LymphomaView official trial listing → -
Completed NCT NCT02661035
Allo HSCT Using RIC for Hematological Diseases
Not yet reported Masonic Cancer Center, University of Minnesota 156 participants Est. completion 2023-05-29 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, B-Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Leukemia, Lymphoblastic Lymphoma, Burkitt's Lymphoma, Non-Hodgkin's Lymphoma, Multiple Myeloma, Myeloproliferative Syndromes, Hematological DiseasesView official trial listing → -
Active, not recruiting NCT NCT02665065
Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported Actinium Pharmaceuticals 153 participants Est. completion 2026-12 24 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Leukemia, Acute Myeloid, Myeloid Leukemia, Acute, Leukemia, Myeloid, Acute, Acute Myelogenous Leukemia, Leukemia, Acute Myelogenous, Myelogenous Leukemia, Acute, AML, Bone Marrow TransplantView official trial listing → -
Completed NCT NCT02666898
Phase II Trial GA101 Inbrutinib B CLL
Not yet reported French Innovative Leukemia Organisation 135 participants Est. completion 2023-09 1 site Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Status unknown NCT NCT02670564
ALL SCTped FORUM - Pharmacogenomic Study (add-on Study)
Not yet reported Swiss Pediatric Oncology Group 1000 participants Est. completion 2026-04 4 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT02672501
A Study to Assess CD19-targeted Immunotherapy T Cells in Patients With Relapsed or Refractory CD19+ B Cell Leukemia
Not yet reported, Not yet reported Shanghai GeneChem Co., Ltd. 30 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Leukemia, B-CellView official trial listing → -
Terminated NCT NCT02676323
Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported St. Jude Children's Research Hospital 19 participants Est. completion 2018-04-09 7 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT02678143
Nonmyeloablative Conditioning for Mismatched Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Disease
Not yet reported Washington University School of Medicine 1 participants Est. completion 2021-11-16 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Withdrawn NCT NCT02680951
Dasatinib in Combination With Chemotherapy for Relapsed or Refractory Core Binding Factor Acute Myeloid Leukemia
Not yet reported Emory University Est. completion 2017-12-15 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT02685670
Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma
Not yet reported, Not yet reported The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine 20 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Hematopoietic/Lymphoid Cancer, Adult Acute Lymphoblastic Leukemia in Remission, B-cell Adult Acute Lymphoblastic Leukemia, B-cell Chronic Lymphocytic Leukemia, Recurrent Adult Diffuse Large Cell Lymphoma, Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma, Recurrent Grade 3 Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Refractory Chronic Lymphocytic Leukemia, Stage III Adult Diffuse Large Cell Lymphoma, Stage III Chronic Lymphocytic Leukemia, Stage III Grade 1 Follicular Lymphoma, Stage III Grade 2 Follicular Lymphoma, Stage III Grade 3 Follicular Lymphoma, Stage III Mantle Cell Lymphoma, Stage IV Adult Diffuse Large Cell Lymphoma, Stage IV Chronic Lymphocytic Leukemia, Stage IV Grade 1 Follicular Lymphoma, Stage IV Grade 2 Follicular Lymphoma, Stage IV Grade 3 Follicular Lymphoma, Stage IV Mantle Cell LymphomaView official trial listing → -
Withdrawn NCT NCT02702960
Sequential, Related Donor Partial Liver Transplantation Followed by Bone Marrow Transplantation for Hepatocellular Carcinoma (HCC)
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Est. completion 2018-01-03 1 site Stand-aloneOther conditions: Fibrolamellar Hepatocellular Carcinoma, Hepatocellular Carcinoma (Fibrolamellar Variant), Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT02706392
Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies
Not yet reported Fred Hutchinson Cancer Center 21 participants Est. completion 2021-09-28 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Triple-Negative Breast Carcinoma, Recurrent Acute Lymphoblastic Leukemia, Recurrent Mantle Cell Lymphoma, Refractory Chronic Lymphocytic Leukemia, Stage III Lung Non-Small Cell Cancer AJCC v7, Stage IIIA Lung Non-Small Cell Cancer AJCC v7, Stage IIIB Lung Non-Small Cell Cancer AJCC v7, Stage IV Breast Cancer AJCC v6 and v7, Stage IV Lung Non-Small Cell Cancer AJCC v7, Unresectable Lung Non-Small Cell CarcinomaView official trial listing → -
Terminated NCT NCT02706405
JCAR014 and Durvalumab in Treating Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported Fred Hutchinson Cancer Center 30 participants Est. completion 2021-05-28 1 site Stand-aloneOther conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements, Refractory Primary Mediastinal (Thymic) Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT02707393
Allogeneic Stem Cell Transplantation for Children With CML
Not yet reported, Not yet reported St. Anna Kinderkrebsforschung 13 participants Est. completion 2020-12-01 4 sites Stand-aloneOther conditions: Chronic Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT02718755
Phase II Study of Fludarabine, Cytarabine (ARA-C) and Erwinase IV in Patients With Relapsed or Refractory Hematologic Malignancies
Not yet reported M.D. Anderson Cancer Center Est. completion 2022-05 Stand-aloneOther conditions: Hematologic MalignancyView official trial listing → -
Withdrawn NCT NCT02722135
A Study to Find a Safe Dose of Volasertib Given in Addition to Standard Salvage Chemotherapy in Children (Age 3 Months to Less Than 18 Years) With Acute Myeloid Leukaemia, in Whom Front-line Chemotherapy Failed
Not yet reported Boehringer Ingelheim Est. completion 2018-09 1 siteOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Completed NCT NCT02722668
UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep
Not yet reported Masonic Cancer Center, University of Minnesota 15 participants Est. completion 2024-02-22 1 site Stand-aloneOther conditions: Acute Leukemia, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia/Lymphoma, Burkitt's Lymphoma, Natural Killer Cell Malignancies, Chronic Myelogenous Leukemia, Myelodysplastic Syndrome, Large-cell Lymphoma, Hodgkin Lymphoma, Multiple Myeloma, Relapsed Chronic Lymphocytic Leukemia, Relapsed Small Lymphocytic Lymphoma, Marginal Zone B-cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-cell Lymphoma, Prolymphocytic Leukemia, Bone Marrow Failure Syndromes, Myeloproliferative Neoplasms/Myelofibrosis, Biphenotypic/Undifferentiated/Prolymphocytic Leukemias, MRD Positive Leukemia, Leukemia or MDS in Aplasia, Relapsed T-Cell Lymphoma, Relapsed Multiple Myeloma, Plasma Cell LeukemiaView official trial listing → -
Active, not recruiting NCT NCT02724163
International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia
Not yet reported University of Birmingham 700 participants Est. completion 2032-12 68 sites Stand-aloneOther conditions: Acute Myeloid LeukaemiaView official trial listing → -
Withdrawn NCT NCT02724904
Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplant (HSCT) For Lymphoma
Not yet reported, Not yet reported Massachusetts General Hospital Est. completion 2021-12 2 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Terminated NCT NCT02737384
Hematopoietic Stem Cells Transplantation in Children With Combined Immunodeficiency (CID)
Not yet reported Assistance Publique - Hôpitaux de Paris 4 participants Est. completion 2017-10-26 1 site Stand-aloneOther conditions: Combined ImmunodeficienciesView official trial listing → -
Completed NCT NCT02743351
Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies
Not yet reported, Not yet reported Fate Therapeutics 96 participants Est. completion 2021-11-05 15 sites Stand-aloneOther conditions: Hematologic Malignancies, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Acute Graft-versus-host DiseaseView official trial listing → -
Terminated NCT NCT02750254
Azacitidine in Haploidentical Donor Hematopoietic Cell Transplantation
Not yet reported Washington University School of Medicine 5 participants Est. completion 2020-10-14 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT02756572
Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid Neoplasms
Not yet reported University of Washington 30 participants Est. completion 2020-07-01 1 site Stand-aloneOther conditions: Blasts 10 Percent or More of Bone Marrow Nucleated Cells, Chronic Myelomonocytic Leukemia-2, High Grade Malignant Neoplasm, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts-2, Myeloid Neoplasm, Previously Treated Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02757885
Transplantation for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone Marrow
Not yet reported Emory University 10 participants Est. completion 2021-12-14 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Status unknown NCT NCT02759822
Haploidentical Hematopoietic Stem Cell Transplantation for Acute Leukemias
Leonardo Javier Arcuri 30 participants 1 siteOther conditions: Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-LymphomaView official trial listing → -
Completed NCT NCT02761915
A Phase I Trial of Anti-GD2 T-cells (1RG-CART)
Not yet reported Cancer Research UK 17 participants Est. completion 2020-12-16 1 siteOther conditions: Relapsed or Refractory NeuroblastomaView official trial listing → -
Completed NCT NCT02763475
NK Cells as Consolidation Therapy of Acute Myeloid Leukemia in Children/Adolescents
Not yet reported Instituto de Investigación Hospital Universitario La Paz 7 participants Est. completion 2020-08 6 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Leukemia, Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02765243
Anti-GD2 4th Generation CART Cells Targeting Refractory and/or Recurrent Neuroblastoma
Not yet reported Zhujiang Hospital 12 participants Est. completion 2023-12-30 1 siteOther conditions: Neuroblastoma, Effects of ImmunotherapyView official trial listing → -
Completed NCT NCT02766465
Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)
Not yet reported Medical College of Wisconsin 138 participants Est. completion 2023-08-02 35 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Status unknown NCT NCT02766868
Sequential Intensive Chemotherapy Followed by RIC for Refractory and Relapse ALL
Not yet reported Shanghai Jiao Tong University School of Medicine 20 participants Est. completion 2019-07 1 site Stand-aloneOther conditions: Lymphoblastic Leukemia, Acute, AdultView official trial listing → -
Completed NCT NCT02771197
Lymphodepletion and Anti-PD-1 Blockade to Reduce Relapse in AML Patient Not Eligible for Transplant
Not yet reported Northside Hospital, Inc. 20 participants Est. completion 2023-07-31 2 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT02774291
Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes
Not yet reported Albert Einstein College of Medicine 3 participants Est. completion 2020-08-04 1 site Stand-aloneOther conditions: HLA-A2 Positive Cells Present, Metastatic Malignant Neoplasm, Metastatic Malignant Neoplasm in the BrainView official trial listing → -
Completed NCT NCT02775292
Gene-Modified T Cells, Vaccine Therapy, and Nivolumab in Treating Patients With Stage IV or Locally Advanced Solid Tumors Expressing NY-ESO-1
Not yet reported Jonsson Comprehensive Cancer Center 1 participants Est. completion 2019-04-08 1 site Stand-aloneOther conditions: Adult Solid Neoplasm, Childhood Solid Neoplasm, Metastatic NeoplasmView official trial listing → -
Status unknown NCT NCT02776202
HLA-Identical Sibling Donor Bone Marrow Transplantation for Individuals With Severe Sickle Cell Disease Using a Reduced Intensity Conditioning Regimen
Not yet reported National Guard Health Affairs 15 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Terminated NCT NCT02781467
A Safety Study of Human Cord Blood Derived, Culture Expanded Natural Killer Cell (PNK-007) Infusion With Subcutaneous Recombinant Human IL-2 (rhIL-2) in Adults With Relapsed and/or Refractory Acute Myeloid Leukemia (AML)
Not yet reported Celularity Incorporated 10 participants Est. completion 2017-12-07 7 sites Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Status unknown NCT NCT02784561
Study of Busulfan and FLAG Conditioning Regimen for Allogeneic Peripheral Blood Stem Cell Transplantation
Not yet reported Chinese PLA General Hospital 80 participants Est. completion 2020-07 Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT02788201
Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma
Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2019-10-23 1 site Stand-aloneOther conditions: Urothelial Carcinoma, Bladder Cancer, Urinary Bladder NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT02790515
Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation
Not yet reported St. Jude Children's Research Hospital 170 participants Est. completion 2026-07-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Myeloid Sarcoma, Chronic Myeloid Leukemia (CML), Juvenile Myelomonocytic Leukemia (JMML), Myelodysplastic Syndrome (MDS), Non-Hodgkin Lymphoma (NHL)View official trial listing → -
Withdrawn NCT NCT02791919
Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported National Cancer Institute (NCI) Est. completion 2019-05-31 Stand-aloneOther conditions: CNS 2a, CNS 2b, CNS 2c, CNS1, Recurrent Adult Acute Myeloid Leukemia, Recurrent Childhood Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02793544
HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation Cyclophosphamide
Not yet reported Center for International Blood and Marrow Transplant Research 80 participants Est. completion 2020-03 11 sitesOther conditions: Myelodysplastic Syndrome (MDS), Chronic Lymphocytic Leukemia (CLL), Chemotherapy-sensitive Lymphoma, Acute Lymphoblastic Leukemia (ALL)/T Lymphoblastic Lymphoma, Acute Myelogenous Leukemia (AML), Acute Biphenotypic Leukemia (ABL), Acute Undifferentiated Leukemia (AUL)View official trial listing → -
Completed NCT NCT02799147
GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia
Not yet reported, Not yet reported St. Petersburg State Pavlov Medical University 27 participants Est. completion 2020-11 1 site Stand-aloneOther conditions: Leukemia, Acute Lymphoblastic, Acute Myeloid Leukemia, Mixed-Lineage Acute LeukemiasView official trial listing → -
Completed NCT NCT02806375
PTCy and Ruxolitinib GVHD Prophylaxis in Myelofibrosis
Not yet reported, Not yet reported St. Petersburg State Pavlov Medical University 20 participants Est. completion 2019-04 1 site Stand-aloneOther conditions: Primary Myelofibrosis, Myeloproliferative DisordersView official trial listing → -
Status unknown NCT NCT02809092
Interleukin-21 (IL-21)- Expanded Natural Killer Cells for Induction of Acute Myeloid Leukemia
Not yet reported, Not yet reported Hospital de Clinicas de Porto Alegre 30 participants Est. completion 2020-09 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02833805
NMA Haplo or MUD BMT for Newly Diagnosed Severe Aplastic Anemia
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 21 participants Est. completion 2021-07 1 site Stand-aloneOther conditions: Severe Aplastic Anemia, Aplastic Anemia, Bone Marrow Failure, ImmunosuppressionView official trial listing → -
Status unknown NCT NCT02842138
Autologous CD19 CAR T Cells in Relapsed or Refractory B-cell Lymphoma
Not yet reported Peking University 25 participants Est. completion 2019-08 1 site Stand-aloneOther conditions: B-cell LymphomaView official trial listing → -
Status unknown NCT NCT02844062
Pilot Study of Autologous Anti-EGFRvIII CAR T Cells in Recurrent Glioblastoma Multiforme
Not yet reported Beijing Sanbo Brain Hospital 20 participants Est. completion 2019-07 1 site Stand-aloneOther conditions: Glioblastoma MultiformeView official trial listing → -
Withdrawn NCT NCT02844530
Study Evaluating the Efficacy of 90Yttrium-epratuzumab in Adults With CD22+ Relapsed/Refractory B-ALL
Not yet reported Nantes University Hospital Est. completion 2017-01 1 siteOther conditions: CD22+ Relapsed/Refractory B-ALLView official trial listing → -
Completed NCT NCT02845596
Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia
Not yet reported Michael Pulsipher 40 participants Est. completion 2023-07-19 13 sitesOther conditions: Severe Aplastic AnemiaView official trial listing → -
Completed NCT NCT02845999
Allogenic Immunotherapy Based on Natural Killer (NK) Cell Adoptive Transfer in Metastatic Gastrointestinal Carcinoma Treated With Cetuximab
Not yet reported Centre Hospitalier Universitaire de Besancon 9 participants 1 site Stand-aloneOther conditions: Gastrointestinal Metastatic CancerView official trial listing → -
Completed NCT NCT02858310
E7 TCR T Cells for Human Papillomavirus-Associated Cancers
Not yet reported, Not yet reported National Cancer Institute (NCI) 224 participants Est. completion 2025-07-02 2 sites Stand-aloneOther conditions: Papillomavirus Infections, Cervical Intraepithelial Neoplasia, Carcinoma In Situ, Vulvar Neoplasms, Vulvar DiseasesView official trial listing → -
Active, not recruiting NCT NCT02861417
Busulfan, Fludarabine Phosphate, and Post-Transplant Cyclophosphamide in Treating Patients With Blood Cancer Undergoing Donor Stem Cell Transplant
Not yet reported M.D. Anderson Cancer Center 204 participants Est. completion 2028-08-31 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell Neoplasm, High Risk Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, Lymphoproliferative Disorder, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent High Risk Myelodysplastic Syndrome, Recurrent Hodgkin Lymphoma, Recurrent Myelodysplastic Syndrome, Recurrent Non-Hodgkin Lymphoma, Recurrent Plasma Cell MyelomaView official trial listing → -
Active, not recruiting NCT NCT02869217
Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors
Not yet reported University Health Network, Toronto 22 participants Est. completion 2026-11 1 site Stand-aloneOther conditions: NY-ESO-1 Expressing Solid Tumors in HLA-A2 Positive Patients, Synovial Sarcoma, Melanoma, Esophageal Cancer, Ovarian Cancer, Lung Cancer, Bladder Cancer, Liver CancerView official trial listing → -
Completed NCT NCT02876510
ACTolog in Patients With Solid Cancers
Not yet reported Immatics US, Inc. 38 participants Est. completion 2021-09-22 1 site Stand-aloneOther conditions: Cancer, Solid TumorView official trial listing → -
Status unknown NCT NCT02876978
Anti-GPC3 CAR T for Recurrent or Refractory Lung Squamous Cell Carcinoma
Not yet reported CARsgen Therapeutics Co., Ltd. 20 participants Est. completion 2019-04 1 site Stand-aloneOther conditions: Lung Squamous Cell CarcinomaView official trial listing → -
Completed NCT NCT02880293
Haploidentical (Half-matched) Related Donor Stem Cell Transplantation Using Killer Immunoglobulin-like Receptors in Addition to Normal Selection Factors to Determine the Best Donor
Not yet reported Memorial Sloan Kettering Cancer Center 44 participants Est. completion 2023-11-20 1 site Stand-aloneOther conditions: Hematologic MalignancyView official trial listing → -
Completed NCT NCT02881086
Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment
Not yet reported Goethe University 1023 participants Est. completion 2024-12 1 siteOther conditions: Acute Lymphoblastic Leukemia, Lymphoblastic LymphomaView official trial listing → -
Status unknown NCT NCT02894645
Malaysia-Singapore Acute Lymphoblastic Leukemia 2010 Study
Not yet reported National University Hospital, Singapore 500 participants 4 sitesOther conditions: Acute Lymphoblastic Leukemia (ALL)View official trial listing → -
Completed NCT NCT02905188
Glypican 3-specific Chimeric Antigen Receptor Expressing T Cells for Hepatocellular Carcinoma (GLYCAR)
Not yet reported Baylor College of Medicine 9 participants Est. completion 2023-01-06 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT02916979
Myeloid-Derived Suppressor Cells and Checkpoint Immune Regulators' Expression in Allogeneic SCT Using FluBuATG
Not yet reported Dartmouth-Hitchcock Medical Center 20 participants Est. completion 2022-02-11 1 siteOther conditions: Leukemia, Lymphoid, Leukemia, Myeloid, Myelodysplastic Syndromes, Myelofibrosis, Lymphoma, Malignant, Multiple Myeloma, Waldenstrom MacroglobulinemiaView official trial listing → -
Completed NCT NCT02917096
Ruxolitinib Phosphate and Chemotherapy Given Before and After Reduced Intensity Donor Stem Cell Transplant in Treating Patients With Myelofibrosis
Not yet reported City of Hope Medical Center 18 participants Est. completion 2023-08-31 1 site Stand-aloneOther conditions: Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Completed NCT NCT02918292
Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)
Not yet reported Medical College of Wisconsin 32 participants Est. completion 2021-08-17 28 sites Stand-aloneOther conditions: Severe Aplastic AnemiaView official trial listing → -
Status unknown NCT NCT02924753
The Safety and Efficacy of CART-19 Cells in B-cell Acute Lymphoblastic Leukemia (B-ALL).
Not yet reported Henan Cancer Hospital 20 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT02926053
TIL Therapy for Metastatic Renal Cell Carcinoma
Not yet reported Inge Marie Svane 5 participants Est. completion 2021-10-31 1 site Stand-aloneOther conditions: Metastatic Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT02926586
Fludarabine and Cytarabine Versus High-dose Cytarabine for CBF-AML
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 68 participants Est. completion 2024-07 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Core-Binding FactorView official trial listing → -
Completed NCT NCT02926833
Study of Safety and Efficacy of KTE-C19 in Combination With Atezolizumab in Adults With Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Not yet reported, Not yet reported Kite, A Gilead Company 37 participants Est. completion 2023-01-12 5 sites Stand-aloneOther conditions: Refractory Diffuse Large B Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT02928991
Fludarabine Based RIC for Bone Marrow Failure Syndromes
Not yet reported Children's Hospital of Philadelphia 25 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Bone Marrow Failure SyndromesView official trial listing → -
Active, not recruiting NCT NCT02932956
Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Patients With Pediatric Solid Tumors (GAP)
Not yet reported Baylor College of Medicine 10 participants Est. completion 2037-02 1 site Stand-aloneOther conditions: Liver CancerView official trial listing → -
Status unknown NCT NCT02933775
CD19-redirected Autologous Cells (CAR-CD19 T Cells)
Not yet reported RenJi Hospital 45 participants Est. completion 2020-01 1 site Stand-aloneOther conditions: CD19 Positive Malignant B-cell Leukemia and LymphomaView official trial listing → -
Status unknown NCT NCT02937844
Pilot Study of Autologous Chimeric Switch Receptor Modified T Cells in Recurrent Glioblastoma Multiforme
Not yet reported Beijing Sanbo Brain Hospital 20 participants Est. completion 2019-07 1 site Stand-aloneOther conditions: Glioblastoma MultiformeView official trial listing → -
Completed NCT NCT02950051
Standard Chemoimmunotherapy (FCR/BR) Versus Rituximab + Venetoclax (RVe) Versus Obinutuzumab (GA101) + Venetoclax (GVe) Versus Obinutuzumab + Ibrutinib + Venetoclax (GIVe) in Fit Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without Del(17p) or TP53 Mutation
Not yet reported German CLL Study Group 926 participants Est. completion 2024-02-29 161 sitesOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT02959905
Treatment of Advanced Solid Tumors With TSA-CTL(Tumor Specific Antigen-Induced Cytotoxic T Lymphocytes)
Not yet reported BGI, China 11 participants Est. completion 2022-05-20 1 site Stand-aloneOther conditions: Solid CancerView official trial listing → -
Completed NCT NCT02988466
Reduced Intensity (RIC) Conditioning And Transplantation of HLA-Haplo-HCT
Not yet reported Masonic Cancer Center, University of Minnesota 78 participants Est. completion 2025-03-24 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Active, not recruiting NCT NCT02990819
Alpha/Beta T and CD19+ Depleted Peripheral Stem Cells for Patients With Primary Immunodeficiencies
Not yet reported Children's Hospital of Philadelphia 60 participants Est. completion 2027-12 1 siteOther conditions: Immunodeficiencies, Immune Dysregulation SyndromesView official trial listing → -
Terminated NCT NCT02991898
Adoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme Malignancies
Not yet reported Masonic Cancer Center, University of Minnesota 3 participants Est. completion 2019-06-20 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Burkitt Lymphoma, Natural Killer Cell Malignancies, Chronic Myelogenous Leukemia, Myelodysplastic Syndromes, Large-cell Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone B-Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Leukemia, Hodgkin Lymphoma, Multiple Myeloma, Acute Myelogenous Leukemia, Biphenotypic Leukemia, Undifferentiated LeukemiaView official trial listing → -
Completed NCT NCT02992743
Letetresgene Autoleucel Engineered T Cells in NY-ESO-1 Positive Participants With Advanced Myxoid/ Round Cell Liposarcoma
Not yet reported GlaxoSmithKline 23 participants Est. completion 2022-03-22 6 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT03016377
Administration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL
Not yet reported UNC Lineberger Comprehensive Cancer Center 15 participants Est. completion 2037-09-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Immune System Diseases, Immunoproliferative DisordersView official trial listing → -
Status unknown NCT NCT03016988
The Efficacy and Safety of Bortezomib Combined With Fludarabine and Cytarabine Treatment for Mantle Cell Lymphoma
Not yet reported Tingbo Liu 50 participants Est. completion 2020-12Other conditions: Mantle Cell LymphomaView official trial listing → -
Completed NCT NCT03018223
Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 32 participants Est. completion 2021-03-18 1 site Stand-aloneOther conditions: Non-Hodgkin's Lymphoma, Acute Leukemia in Remission, Chronic Myeloid Leukemia, Primary Myelofibrosis, Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Hodgkin Lymphoma, Multiple MyelomaView official trial listing → -
Completed NCT NCT03019666
Ph I Trial of NAM NK Cells and IL-2 for Adult Pts With MM and NHL
Not yet reported Masonic Cancer Center, University of Minnesota 39 participants Est. completion 2022-08-15 1 site Stand-aloneOther conditions: Multiple Myeloma, Non-Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, Mantle-Cell Lymphoma, Follicular Lymphoma, Indolent B Cell Lymphoma, Primary Mediastinal Lymphoma, Lymphoplasmacytic LymphomaView official trial listing → -
Status unknown NCT NCT03029273
NY-ESO-1 TCR (TAEST16001)for Patients With Advanced NSCLC
Not yet reported Guangzhou Institute of Respiratory Disease 20 participants Est. completion 2019-03 1 site Stand-aloneOther conditions: Lung Cancer, Nonsmall Cell, RecurrentView official trial listing → -
Completed NCT NCT03035422
Sequential Conditioning in Haploidentical Transplantation for Refractory Acute Myeloid Leukemia
Not yet reported Association for Training, Education, and Research in Hematology, Immunology, and Transplantation 24 participants Est. completion 2021-12-18 1 siteOther conditions: Refractory Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT03047811
The Study of Targeted NY-ESO-1 T Cell Receptor (TCR) Genetic Modified Autologous T Cells Treatment of Advanced Solid Tumors
Not yet reported Fudan University 15 participants Est. completion 2017-12-31 1 site Stand-aloneOther conditions: Advanced Malignant Solid TumorsView official trial listing → -
Completed NCT NCT03049449
T Cells Expressing a Fully-Human Anti-CD30 Chimeric Antigen Receptor for Treating CD30-Expressing Lymphomas
Not yet reported National Cancer Institute (NCI) 26 participants Est. completion 2022-01-26 1 site Stand-aloneOther conditions: Lymphoma, Large-Cell, Anaplastic, Enteropathy-Associated T-Cell Lymphoma, Lymphoma, Large B-Cell, Diffuse, Lymphoma, Extranodal NK-T-Cell, Lymphoma, T-Cell, PeripheralView official trial listing → -
Completed NCT NCT03050216
QUILT-3.033: Haplo NK With SQ ALT-803 for Adults With Relapsed or Refractory AML
Not yet reported Masonic Cancer Center, University of Minnesota 8 participants Est. completion 2019-12-15 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03054298
CAR T Cells in Mesothelin Expressing Cancers
Not yet reported University of Pennsylvania 65 participants Est. completion 2024-07-30 1 siteOther conditions: Lung Adenocarcinoma, Ovarian Cancer, Peritoneal Carcinoma, Fallopian Tube Cancer, Mesotheliomas Pleural, Mesothelioma PeritoneumView official trial listing → -
Completed NCT NCT03056339
Umbilical & Cord Blood (CB) Derived CAR-Engineered NK Cells for B Lymphoid Malignancies
Not yet reported, Not yet reported M.D. Anderson Cancer Center 49 participants Est. completion 2023-03-06 1 site Stand-aloneOther conditions: B-Lymphoid Malignancies, Acute Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, Non-hodgkin LymphomaView official trial listing → -
Completed NCT NCT03068819
Cytokine Induced Memory-like NK Cell Adoptive Therapy for Relapsed AML After Allogeneic Hematopoietic Cell Transplant
Not yet reported, Not yet reported Washington University School of Medicine 62 participants Est. completion 2025-06-15 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03070327
BCMA Targeted CAR T Cells With or Without Lenalidomide for the Treatment of Multiple Myeloma
Not yet reported Memorial Sloan Kettering Cancer Center 20 participants Est. completion 2027-02 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Terminated NCT NCT03071276
Selinexor in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 37 participants Est. completion 2019-04-30 7 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT03076437
Anti-CD19 Chimeric Antigen Receptor (CAR)-Transduced T Cell Therapy for Patients With B Cell Malignancies
Not yet reported, Not yet reported Shenzhen Institute for Innovation and Translational Medicine 28 participants Est. completion 2019-12-31 1 site Stand-aloneOther conditions: Acute Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, LymphomaView official trial listing → -
Completed NCT NCT03079089
Sequential Conditioning in Haploidentical Transplantation for Hematopoietic Stem Cells in Patients With Relapsed or Refractory Lymphoid Hematological Disorders
Not yet reported Association for Training, Education, and Research in Hematology, Immunology, and Transplantation 40 participants Est. completion 2023-09-11 1 siteOther conditions: Refractory or Relapsed Lymphoid HaemopathyView official trial listing → -
Completed NCT NCT03081780
Open Label NK Cell Infusion (FATE-NK100) With Subq IL-2 in Adults With AML
Not yet reported Masonic Cancer Center, University of Minnesota 6 participants Est. completion 2020-12-01 1 site Stand-aloneOther conditions: Refractory Acute Myelogenous Leukemia, Relapsed Acute Myelogenous LeukemiaView official trial listing → -
Status unknown NCT NCT03084380
Anti-GPC3 CAR-T for Treating GPC3-positive Advanced Hepatocellular Carcinoma (HCC)
Not yet reported, Not yet reported Xinqiao Hospital of Chongqing 20 participants Est. completion 2020-05-31 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03089203
CART-PSMA-TGFβRDN Cells for Castrate-Resistant Prostate Cancer
Not yet reported University of Pennsylvania 23 participants Est. completion 2038-12-08 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Status unknown NCT NCT03093168
BCMA Chimeric Antigen Receptor Expressing T Cells in Multiple Myeloma
Not yet reported The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine 10 participants Est. completion 2020-02 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT03096782
Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma
Not yet reported M.D. Anderson Cancer Center 6 participants Est. completion 2022-09-20 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Biphenotypic Leukemia, Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Chemotherapy-Related Leukemia, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Myelomonocytic Leukemia, Hodgkin Lymphoma, Langerhans Cell Histiocytosis, Minimal Residual Disease, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts, Non-Hodgkin Lymphoma, Recurrent Hodgkin Lymphoma, Refractory Acute Lymphoblastic Leukemia, Refractory Myelodysplastic Syndrome, Small Lymphocytic Lymphoma, Therapy-Related Myelodysplastic SyndromeView official trial listing → -
Status unknown NCT NCT03101709
The Safety and Efficacy of CART-19 Cells in Relapse and Refractory Patients With CD19+ B-cell Lymphoma
Not yet reported Henan Cancer Hospital 30 participants Est. completion 2019-07 1 site Stand-aloneOther conditions: B Cell LymphomaView official trial listing → -
Terminated NCT NCT03103971
huJCAR014 CAR-T Cells in Treating Adult Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia
Not yet reported Fred Hutchinson Cancer Center 55 participants Est. completion 2024-03-23 1 site Stand-aloneOther conditions: Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Refractory Adult Acute Lymphoblastic Leukemia, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Recurrent Transformed Non-Hodgkin Lymphoma, Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements, Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements, Refractory B Acute Lymphoblastic Leukemia, Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 RearrangementsView official trial listing → -
Completed NCT NCT03105336
A Study of Axicabtagene Ciloleucel in Participants With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma
Not yet reported Kite, A Gilead Company 159 participants Est. completion 2024-12-20 19 sites Stand-aloneOther conditions: Follicular Lymphoma, Marginal Zone Lymphoma, Indolent Non-Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT03110640
Anti-CD19 CAR T Infusion Combined With Allogeneic Stem Cell Transplantation for B-cell Leukemia/Lymphoma
Not yet reported First Affiliated Hospital of Wenzhou Medical University 20 participants Est. completion 2021-09 1 site Stand-aloneOther conditions: B-cell Adult Acute Lymphoblastic Leukemia, B-cell Chronic Lymphocytic Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Hematopoietic/Lymphoid Cancer, Refractory Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT03114670
Donor-derived Anti-CD123-CART Cells for Recurred AML After Allo-HSCT
Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 20 participants Est. completion 2021-03-18 1 siteOther conditions: Adult Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03118492
Combination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Secondary Myelofibrosis
Not yet reported City of Hope Medical Center 22 participants Est. completion 2027-04-29 1 site Stand-aloneOther conditions: Secondary MyelofibrosisView official trial listing → -
Active, not recruiting NCT NCT03121014
Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes
Not yet reported University of Illinois at Chicago 38 participants Est. completion 2026-04 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Terminated NCT NCT03126864
Study of Adoptive Cellular Therapy Using Autologous T Cells Transduced With Lentivirus to Express a CD33 Specific Chimeric Antigen Receptor in Patients With Relapsed or Refractory CD33-Positive Acute Myeloid Leukemia
Not yet reported M.D. Anderson Cancer Center 11 participants Est. completion 2019-10-10 1 site Stand-aloneOther conditions: Hematopoietic/Lymphoid Cancer, Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03128359
High Dose Cyclophosphamide, Tacrolimus, and Mycophenolate Mofetil in Preventing Graft Versus Host Disease in Patients With Hematological Malignancies Undergoing Myeloablative or Reduced Intensity Donor Stem Cell Transplant
Not yet reported City of Hope Medical Center 38 participants Est. completion 2021-09-15 1 site Stand-aloneOther conditions: Acute Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Graft Versus Host Disease, Hodgkin Lymphoma, Mantle Cell Lymphoma, Marginal Zone Lymphoma, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes, Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma, Secondary Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT03139370
Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers
Not yet reported Kite, A Gilead Company 16 participants Est. completion 2023-06-04 12 sites Stand-aloneOther conditions: Solid TumorView official trial listing → -
Status unknown NCT NCT03142646
Safety and Efficacy Evaluation of IM19 CAR-T Cells
Not yet reported, Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 60 participants Est. completion 2018-10-01 2 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT03146234
CAR-GPC3 T Cells in Patients With Refractory Hepatocellular Carcinoma
Not yet reported RenJi Hospital 7 participants Est. completion 2018-10-18 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT03146533
CD19 CART Cells for Patients With Relapse and Refractory CD19+ B-cell Lymphoma.
Not yet reported, Not yet reported Shenzhen Second People's Hospital 20 participants Est. completion 2019-10 1 site Stand-aloneOther conditions: B Cell LymphomaView official trial listing → -
Completed NCT NCT03158935
The ACTIVATE (Adoptive Cell Therapy InVigorated to Augment Tumor Eradication) Trial
Not yet reported University Health Network, Toronto 8 participants Est. completion 2020-08-04 1 site Stand-aloneOther conditions: Advanced Ovarian Cancer, Malignant MelanomaView official trial listing → -
Completed NCT NCT03159585
To Evaluate the Efficacy of NY-ESO-1-specific T Cell Receptor Affinity Enhancing Specific T Cell in Solid Tumors
Not yet reported Zhujiang Hospital 6 participants Est. completion 2019-06-04 1 site Stand-aloneOther conditions: Liver Cancer Stage IV, Gastric Cancer Stage IV, Esophageal Cancer, Stage IV, Bone and Soft Tissue Tumors, Breast Cancer Stage IV, Bladder Carcinoma Stage IV, Prostate Carcinoma Stage IV, Thyroid Cancer Stage IV, Ovarian Cancer Stage IV, Solid TumorView official trial listing → -
Completed NCT NCT03159702
Propylene Glycol-Free Melphalan HCl (EVOMELA®) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical Transplantation
Not yet reported Medical College of Wisconsin 43 participants Est. completion 2025-12-08 1 site Stand-aloneOther conditions: Hematological Malignancy, Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT03164057
A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 206 participants Est. completion 2027-06 10 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT03166397
Adoptive Cell Therapy Following a Non-myeloablative, Lymphodepleting Induction Regimen in Metastatic Melanoma Patients
Not yet reported Sheba Medical Center 30 participants Est. completion 2026-06-01 1 site Stand-aloneOther conditions: Malignant Melanoma Stage IVView official trial listing → -
Terminated NCT NCT03168438
Letetresgene Autoleucel Engineered T Cells Alone and in Combination With Pembrolizumab in NY-ESO-1 Positive Multiple Myeloma
Not yet reported GlaxoSmithKline 6 participants Est. completion 2020-11-05 5 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Terminated NCT NCT03170141
Immunogene-modified T (IgT) Cells Against Glioblastoma Multiforme
Not yet reported Shenzhen Geno-Immune Medical Institute 30 participants Est. completion 2026-07-31 1 site Stand-aloneOther conditions: Glioblastoma Multiforme of Brain, Brain CancerView official trial listing → -
Status unknown NCT NCT03171220
Neoantigen Reactive T Cells Combined With SHR-1210 for Chinese Patients With Advanced Refractory Solid Tumors
Not yet reported, Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 40 participants Est. completion 2020-12-31 1 site Stand-aloneOther conditions: Advanced Malignant Solid TumorView official trial listing → -
Status unknown NCT NCT03171831
Haploidentical Hematopoietic Stem Cell Transplantation for Patients With Thalassemia Major
Not yet reported First Affiliated Hospital of Guangxi Medical University 30 participants Est. completion 2022-04-01 1 site Stand-aloneOther conditions: Thalassemia MajorView official trial listing → -
Completed NCT NCT03173417
Safety and Efficacy Evaluation of IM19 CAR-T Cells (IM19CAR-T)
Not yet reported, Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 177 participants Est. completion 2019-05-01 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT03182244
A Study of ASP2215 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase 3 (FLT3) Mutation
Not yet reported Astellas Pharma Inc 276 participants Est. completion 2026-07-29 49 sitesOther conditions: AML With FLT3 MutationView official trial listing → -
Status unknown NCT NCT03190733
A Optimal Anti-Thymoglobuline (ATG) Dose Decrease cGVHD But Not Increase Leukemia Relapse for Haplo-HSCT
Not yet reported Zhujiang Hospital 192 participants Est. completion 2021-09-30 Stand-aloneOther conditions: Chronic Graft-versus-host-disease, Leukemia RelapseView official trial listing → -
Status unknown NCT NCT03191773
A Study of Anti-CD19 CAR-T Cell Immunotherapy for Refractory /Relapsed B Cell Malignancies
Not yet reported, Not yet reported Second Affiliated Hospital of Guangzhou Medical University 100 participants Est. completion 2020-12-31 5 sites Stand-aloneOther conditions: Acute Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, LymphomaView official trial listing → -
Active, not recruiting NCT NCT03192397
Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant
Not yet reported, Not yet reported Roswell Park Cancer Institute 35 participants Est. completion 2027-05-21 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia in Remission, Adult Acute Lymphoblastic Leukemia in Complete Remission, Chronic Myelogenous Leukemia, BCR-ABL1 Positive in Remission, Chronic Myelomonocytic Leukemia in Remission, Graft Versus Host Disease, Hodgkin Lymphoma, Minimal Residual Disease, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Non-Hodgkin Lymphoma, Plasma Cell Myeloma, Severe Aplastic Anemia, Waldenstrom MacroglobulinemiaView official trial listing → -
Completed NCT NCT03204188
Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 15 participants Est. completion 2026-01-09 1 site Stand-aloneOther conditions: B-Cell Chronic Lymphocytic Leukemia, B-Lymphocytic Leukemia, Chronic, Chronic Lymphocytic Leukemia, Leukemia, Chronic Lymphatic, Leukemia, Chronic Lymphocytic, B-Cell, Leukemia, Lymphocytic, Chronic, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphocytic Leukemia, Chronic, B Cell, Lymphocytic Leukemia, Chronic, B-CellView official trial listing → -
Status unknown NCT NCT03208556
Safety and Efficacy of iPD1 CD19 eCAR T Cells in Relapsed or Refractory B-cell Lymphoma
Not yet reported Peking University 20 participants Est. completion 2020-06-01 1 site Stand-aloneOther conditions: Relapsed or Refractory B-cell LymphomaView official trial listing → -
Completed NCT NCT03213964
Intraperitoneal Delivery of Adaptive Natural Killer (NK) Cells (FATE-NK100) With Intraperitoneal Int
Not yet reported Masonic Cancer Center, University of Minnesota 10 participants Est. completion 2021-03-10 1 site Stand-aloneOther conditions: Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal CancerView official trial listing → -
Completed NCT NCT03215810
Nivolumab and Tumor Infiltrating Lymphocytes (TIL) in Advanced Non-Small Cell Lung Cancer
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 20 participants Est. completion 2023-06-09 2 sites Stand-aloneOther conditions: Non-Small Cell Lung Cancer, Metastatic Non-small Cell Lung Cancer, Squamous Cell Carcinoma, Advanced NSCLC, Adenosquamous Carcinoma, AdenocarcinomasView official trial listing → -
Suspended NCT NCT03229876
Safety and Efficacy Evaluation of CD19-UCART
Not yet reported Bioray Laboratories 20 participants Est. completion 2023-12-30 2 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL), Non Hodgkin Lymphoma (NHL)View official trial listing → -
Active, not recruiting NCT NCT03233854
CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignancies
Not yet reported Stanford University 56 participants Est. completion 2035-09-01 1 site Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, CD19 Positive, Minimal Residual Disease, Philadelphia Chromosome PositiveView official trial listing → -
Status unknown NCT NCT03235973
Cladribine Dose Escalation in Conditioning Regimen Prior to Allo-HSCT for Refractory Acute Leukemia and Myelodysplastic Syndromes
Not yet reported Institut Paoli-Calmettes 29 participants Est. completion 2021-04 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Leukemia, Lymphoblastic, AcuteView official trial listing → -
Status unknown NCT NCT03236129
Allogeneic Immunotherapy for Hematological Malignancies by Selective Depletion of Regulatory T Cells
Not yet reported Assistance Publique - Hôpitaux de Paris 52 participants Est. completion 2026-02 1 site Stand-aloneOther conditions: Hematological Malignancies, Regulatory T Cell Depletion, RelapseView official trial listing → -
Completed NCT NCT03240731
HLA Haploidentical Bone Marrow Transplant in Patients With Severe Sickle Cell Disease
Not yet reported Centre Hospitalier Intercommunal Creteil 25 participants Est. completion 2024-04-08 7 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Terminated NCT NCT03240861
Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer
Not yet reported Jonsson Comprehensive Cancer Center 5 participants Est. completion 2023-10-19 1 site Stand-aloneOther conditions: HLA-A*0201 Positive Cells Present, Locally Advanced Malignant Neoplasm, NY-ESO-1 Positive, Unresectable Malignant Neoplasm, SarcomaView official trial listing → -
Active, not recruiting NCT NCT03241940
Study of CD19/CD22 Chimeric Antigen Receptor T Cells in Children & Young Adults w/ Recurrent or Refractory B Cell Malignancies
Not yet reported Stanford University 33 participants Est. completion 2035-08-01 1 site Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, CD19 Positive, Minimal Residual Disease, Philadelphia Chromosome Positive, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT03246178
Haploidentical Transplantation in Severe Aplastic Anemia
Not yet reported Wu Xiaoxiong 60 participants Est. completion 2020-12-01 1 site Stand-aloneOther conditions: Severe Aplastic AnemiaView official trial listing → -
Active, not recruiting NCT NCT03247088
Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant
Not yet reported, Not yet reported M.D. Anderson Cancer Center 74 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03247309
TCR-engineered T Cells in Solid Tumors (ACTengine IMA201-101)
Not yet reported Immatics US, Inc. 7 participants Est. completion 2023-09-18 5 sites Stand-aloneOther conditions: Solid Tumor, Cancer, Recurrent Solid Tumors, Refractory Solid TumorsView official trial listing → -
Completed NCT NCT03250338
Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML
Not yet reported Arog Pharmaceuticals, Inc. 106 participants Est. completion 2026-04-03 62 sites Stand-aloneOther conditions: Relapsed/Refractory Acute Myeloid Leukemia With FLT3 Activating MutationsView official trial listing → -
Status unknown NCT NCT03257241
A PALG Prospective Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) and Two Standard Salvage Regimens (FLAG-IDA vs CLAG-M) in AML Patients ≤ 60 Years Old
Not yet reported Polish Adult Leukemia Group 582 participants Est. completion 2022-12-31 10 sitesOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT03259516
Nivolumab With Chemotherapy in Refractory MDS
Not yet reported, Not yet reported St. Petersburg State Pavlov Medical University 2 participants Est. completion 2018-12-25 1 site Stand-aloneOther conditions: Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT03263208
CD19 CAR-T Cells for Patients With Relapse and Refractory CD19+ B-ALL.
Not yet reported, Not yet reported Henan Cancer Hospital 20 participants Est. completion 2019-07 2 sites Stand-aloneOther conditions: B-cell Acute Lymphocytic LeukemiaView official trial listing → -
Completed NCT NCT03263559
Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)
Not yet reported Medical College of Wisconsin 95 participants Est. completion 2025-01-29 32 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Terminated NCT NCT03263767
Post Transplant Cyclophosphamide (PTCY) as Sole Graft Versus Host Disease (GVHD) Prophylaxis for Matched Allotransplant: CYRIC
Not yet reported Nantes University Hospital 47 participants Est. completion 2022-06-21 1 site Stand-aloneOther conditions: Graft Versus Host DiseaseView official trial listing → -
Completed NCT NCT03263936
Epigenetic Reprogramming in Relapse/Refractory AML
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 37 participants Est. completion 2022-02-10 33 sitesOther conditions: Acute Myelogenous LeukemiaView official trial listing → -
Completed NCT NCT03270748
Post Transplant High-Dose Cy as GvHD Prophylaxis in 1 HLA Mismatched Unrelated HSCT for Myeloid Malignancies
Not yet reported Gruppo Italiano Trapianto di Midollo Osseo 78 participants Est. completion 2022-11-20 33 sites Stand-aloneOther conditions: Myeloid MalignanciesView official trial listing → -
Active, not recruiting NCT NCT03277729
A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 53 participants Est. completion 2039-03 1 site Stand-aloneOther conditions: Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Chronic Lymphocytic Leukemia, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Follicular Lymphoma, Recurrent Lymphoplasmacytic Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Marginal Zone Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Follicular Lymphoma, Refractory Lymphoplasmacytic Lymphoma, Refractory Mantle Cell Lymphoma, Refractory Transformed Non-Hodgkin Lymphoma, Recurrent Transformed B-Cell Non-Hodgkin Lymphoma, Recurrent Transformed Chronic Lymphocytic Leukemia, Refractory Marginal Zone Lymphoma, Refractory Transformed B-Cell Non-Hodgkin Lymphoma, Refractory Transformed Chronic Lymphocytic Leukemia, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Small Lymphocytic Lymphoma, Recurrent Central Nervous System Lymphoma, Refractory Central Nervous System LymphomaView official trial listing → -
Completed NCT NCT03287674
TIL Therapy in Combination With Checkpoint Inhibitors for Metastatic Ovarian Cancer
Not yet reported, Not yet reported Inge Marie Svane 7 participants Est. completion 2020-06-01 1 site Stand-aloneOther conditions: Metastatic Ovarian CancerView official trial listing → -
Terminated NCT NCT03287804
APRIL CAR T Cells (AUTO2) Targeting BCMA and TACI for the Treatment of Multiple Myeloma
Not yet reported, Not yet reported Autolus Limited 12 participants Est. completion 2019-09-05 4 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Terminated NCT NCT03287817
Cluster of Differentiation Antigen 19/22(CD19/22) CAR T Cells (AUTO3) for the Treatment of Diffuse Large B Cell Lymphoma
Not yet reported, Not yet reported Autolus Limited 52 participants Est. completion 2023-10-19 11 sites Stand-aloneOther conditions: Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)View official trial listing → -
Completed NCT NCT03289455
CD19 /22 CAR T Cells (AUTO3) for the Treatment of B Cell Acute Lymphoblastic Leukemia (ALL)
Not yet reported, Not yet reported Autolus Limited 23 participants Est. completion 2020-05-18 3 sites Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia, Recurrent Childhood Acute Lymphoblastic Leukemia, Refractory Childhood Acute Lymphoblastic Leukemia, B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT03295058
Peripheral Blood Allogenic Stem Cell Transplantation Using Non-anti Thymocyte Globulin Regimens in Severe Aplastic Anemia Patients
Not yet reported, Not yet reported Assiut University 50 participants Est. completion 2020-06 Stand-aloneOther conditions: Severe Aplastic AnemiaView official trial listing → -
Completed NCT NCT03296137
Adoptive Cell Therapy Across Cancer Diagnoses
Not yet reported, Not yet reported Inge Marie Svane 25 participants Est. completion 2020-07-01 1 site Stand-aloneOther conditions: CancerView official trial listing → -
Status unknown NCT NCT03298828
CD19 CAR and PD-1 Knockout Engineered T Cells for CD19 Positive Malignant B-cell Derived Leukemia and Lymphoma
Not yet reported Third Military Medical University 30 participants Est. completion 2022-10 Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Burkitt LymphomaView official trial listing → -
Status unknown NCT NCT03302403
Clinical Study of Redirected Autologous T Cells With a Chimeric Antigen Receptor in Patients With Malignant Tumors
Not yet reported Kang YU 18 participants Est. completion 2023-12-12 1 site Stand-aloneOther conditions: B Cell Lymphoma, B Cell Leukemia, Myeloma, Hepatocellular Carcinoma, Pancreatic Carcinoma, Adenocarcinoma of Esophagogastric JunctionView official trial listing → -
Terminated NCT NCT03303950
Allogeneic Stem Cell Transplantation for Multiple Myeloma and Myelofibrosis
Not yet reported University of Utah 6 participants Est. completion 2020-02-19 1 site Stand-aloneOther conditions: Anemia, ASXL1 Gene Mutation, EZH2 Gene Mutation, IDH1 Gene Mutation, IDH2 Gene Mutation, Plasma Cell Myeloma, Primary Myelofibrosis, Recurrent Plasma Cell Myeloma, Secondary Myelofibrosis, ThrombocytopeniaView official trial listing → -
Terminated NCT NCT03318861
Study to Evaluate the Safety and Efficacy of KITE-585 in Participants With Relapsed/Refractory Multiple Myeloma
Not yet reported Kite, A Gilead Company 17 participants Est. completion 2022-09-16 9 sites Stand-aloneOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Status unknown NCT NCT03321123
MB-CART19.1 in Patients With R/R ALL
Not yet reported Shanghai Children's Medical Center 10 participants Est. completion 2019-12-31 Stand-aloneOther conditions: Precursor B-Lymphoblastic Lymphoma/Leukaemia RefractoryView official trial listing → -
Status unknown NCT NCT03322735
Study of BCMA CAR-T in Multiple Myeloma
Not yet reported, Not yet reported Henan Cancer Hospital 10 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Withdrawn NCT NCT03324243
A Study of Crenolanib With Fludarabine and Cytarabine in Pediatric Patients With Relapsed/Refractory FLT3-Mutated Acute Myeloid Leukemia
Not yet reported Arog Pharmaceuticals, Inc. Est. completion 2020-12 Stand-aloneOther conditions: Relapsed/Refractory FLT3-mutated AMLView official trial listing → -
Terminated NCT NCT03330834
CAR-T Cell Immunotherapy for Advanced Lung Cancer
Not yet reported Sun Yat-sen University 1 participants Est. completion 2020-04-14 1 site Stand-aloneOther conditions: Advanced Lung CancerView official trial listing → -
Terminated NCT NCT03333486
Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer
Not yet reported Roswell Park Cancer Institute 31 participants Est. completion 2023-08-28 1 site Stand-aloneOther conditions: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Acute Leukemia in Remission, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia With FLT3/ITD Mutation, Acute Myeloid Leukemia With Gene Mutations, Aplastic Anemia, B-Cell Non-Hodgkin Lymphoma, CD40 Ligand Deficiency, Chronic Granulomatous Disease, Chronic Leukemia in Remission, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Congenital Amegakaryocytic Thrombocytopenia, Congenital Neutropenia, Congenital Pure Red Cell Aplasia, Glanzmann Thrombasthenia, Immunodeficiency Syndrome, Myelodysplastic Syndrome, Myelofibrosis, Myeloproliferative Neoplasm, Paroxysmal Nocturnal Hemoglobinuria, Plasma Cell Myeloma, Polycythemia Vera, Recurrent Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Secondary Acute Myeloid Leukemia, Secondary Myelodysplastic Syndrome, Severe Aplastic Anemia, Shwachman-Diamond Syndrome, Sickle Cell Disease, T-Cell Non-Hodgkin Lymphoma, Thalassemia, Waldenstrom Macroglobulinemia, Wiskott-Aldrich SyndromeView official trial listing → -
Status unknown NCT NCT03335241
Study of Fludarabine With Pegylated Liposomal Doxorubicin Versus Pegylated Liposomal Doxorubicin Alone In Patients With Platinum Resistant/Refractory Ovarian Cancer
Not yet reported Sun Yat-sen University 140 participants Est. completion 2022-12 1 site Stand-aloneOther conditions: Ovarian CancerView official trial listing → -
Status unknown NCT NCT03337568
Allogeneic HCT Using Uniform Conditioning Regimen Regardless of Donors (MS, MU, or HF) for AML in Remission
Asan Medical Center 110 participants Est. completion 2021-03-30 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03338972
Immunotherapy With BCMA CAR-T Cells in Treating Patients With BCMA Positive Relapsed or Refractory Multiple Myeloma
Not yet reported Fred Hutchinson Cancer Center 28 participants Est. completion 2022-03-22 1 site Stand-aloneOther conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell MyelomaView official trial listing → -
Completed NCT NCT03342196
Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor Transplantation
Not yet reported Case Comprehensive Cancer Center 40 participants Est. completion 2024-06-12 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Status unknown NCT NCT03344367
Study Evaluating the Safety and Efficacy of JWCAR029 in Adult Subjects With Relapsed and Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported Peking University 20 participants Est. completion 2022-03 1 site Stand-aloneOther conditions: Non Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT03344705
Safety and Efficacy Evaluation of IM19 Cells
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 20 participants Est. completion 2020-12-01 1 site Stand-aloneOther conditions: Hematological MalignanciesView official trial listing → -
Status unknown NCT NCT03348033
Safety and Feasibility of the Use of Natural Killer Cells in Patients With Chronic Myeloid Leukemia
Not yet reported, Not yet reported Hospital de Clinicas de Porto Alegre 5 participants Est. completion 2023-03 1 site Stand-aloneOther conditions: Chronic Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03354390
HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 17 participants Est. completion 2029-03-03 1 site Stand-aloneOther conditions: Kidney CancerView official trial listing → -
Status unknown NCT NCT03355859
Study Evaluating the Safety and Efficacy of JWCAR029 in Adult Subjects With Relapsed and Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported Zhao Weili 10 participants Est. completion 2022-03 1 site Stand-aloneOther conditions: Non Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT03367546
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Conditioning (RIC) for Selected High Risk Non-Malignant Diseases
Not yet reported Masonic Cancer Center, University of Minnesota 5 participants Est. completion 2022-12-19 1 site Stand-aloneOther conditions: Sickle Cell Disease, Thalassemia, High Risk Hematologic Disorders, Cerebral Adrenoleukodystrophy, Inherited Metabolic DisordersView official trial listing → -
Completed NCT NCT03373071
Anti-CD19 CAR T Cells in Pediatric Patients Affected by Relapsed/Refractory CD19+ ALL and NHL
Not yet reported, Not yet reported Bambino Gesù Hospital and Research Institute 29 participants Est. completion 2025-01-24 1 site Stand-aloneOther conditions: CD19-ALL, CD19-LNHView official trial listing → -
Status unknown NCT NCT03380039
Clinical Study of CAR-BCMA T Cells in Patients With Refractory or Relapsed Multiple Myeloma
Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 6 participants Est. completion 2023-07-02 1 site Stand-aloneOther conditions: Refractory or Relapsed Multiple MyelomaView official trial listing → -
Status unknown NCT NCT03384212
CBA Versus FBA Conditioning Followed by Allogeneic HSCT in Treatment of High Risk and Refractory AML
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 120 participants Est. completion 2022-07-31 1 siteOther conditions: High Risk Acute Myeloid Leukemia, Allogeneic Hematopoeitic Stem Cell TransplantationView official trial listing → -
Status unknown NCT NCT03384225
CBA Versus FBA Conditioning Followed by Haploidentical Allogeneic HSCT in Treatment of High Risk and Refractory AML
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 120 participants Est. completion 2022-07-31 1 siteOther conditions: High Risk Acute Myeloid Leukemia, Allogeneic Hematopoeitic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT03391466
Study of Effectiveness of Axicabtagene Ciloleucel Compared to Standard of Care Therapy in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma
Not yet reported Kite, A Gilead Company 359 participants Est. completion 2024-11-25 72 sites Stand-aloneOther conditions: Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)View official trial listing → -
Completed NCT NCT03393611
CPX-351 Salvage Therapy Followed by Haplo-Cord Transplant for Relapsed/Refractory Leukemia or Myelodysplastic Syndrome
Not yet reported Weill Medical College of Cornell University 14 participants Est. completion 2021-11-18 1 site Stand-aloneOther conditions: Myelodysplastic Syndromes, Leukemia, Myeloid, Acute, Leukemia, Relapsed Adult Acute Myeloid, Myelodysplastic Syndromes, Previously TreatedView official trial listing → -
Terminated NCT NCT03396575
Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)
Not yet reported University of Florida 11 participants Est. completion 2025-03-20 1 site Stand-aloneOther conditions: Diffuse Intrinsic Pontine Glioma (DIPG), Brain Stem GliomaView official trial listing → -
Terminated NCT NCT03399448
NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)
Not yet reported University of Pennsylvania 3 participants Est. completion 2020-10-09 1 site Stand-aloneObstructive sleep apnea Other conditions: Multiple Myeloma, Melanoma, Synovial SarcomaView official trial listing → -
Active, not recruiting NCT NCT03399773
Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes
Not yet reported Fred Hutchinson Cancer Center 31 participants Est. completion 2027-04-02 1 site Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid Cell Neoplasm, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess BlastsView official trial listing → -
Status unknown NCT NCT03412266
RIC Regimen for Low- and Intermediate-risk MDS Receiving Haplo-HSCT
Not yet reported Peking University People's Hospital 50 participants Est. completion 2023-03-01 1 siteOther conditions: Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT03412409
RIC Regimen for Elderly or High Comorbidity Burden Patients Receiving Haplo-HSCT
Not yet reported Peking University People's Hospital 50 participants Est. completion 2025-09-01 1 site Stand-aloneOther conditions: Acute Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT03412526
Adoptive Cell Therapy Following a Reduced Intensity, Non-myeloablative, Lymphodepleting Induction Regimen in Metastatic Ovarian
Not yet reported Sheba Medical Center 15 participants Est. completion 2022-02-01 1 site Stand-aloneOther conditions: Metastatic Ovarian CancerView official trial listing → -
Completed NCT NCT03426969
Combination Chemotherapy, Total Body Irradiation, and Donor Blood Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis
Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2020-09-21 1 site Stand-aloneOther conditions: Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Completed NCT NCT03430011
Study Evaluating the Safety and Efficacy of JCARH125 in Subjects With Relapsed and/or Refractory Multiple Myeloma
Not yet reported, Not yet reported Juno Therapeutics, a Subsidiary of Celgene 165 participants Est. completion 2023-03-30 20 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT03434704
Peripheral Blood Stem Cell Transplantation From Family Haploidentical Donors in Patients With Myelodysplastic Syndrome and Acute Leukemia Under Primary Prophylaxis With Posaconazole
Not yet reported Ciceri Fabio 10 participants Est. completion 2019-10-13 1 site Stand-aloneOther conditions: Transplant-Related Hematologic Malignancy, Leukemia, Acute, Myelodysplastic Syndromes, Graft Vs Host Disease, Fungal InfectionView official trial listing → -
Active, not recruiting NCT NCT03434769
AntiCD19 Chimeric Antigen Receptor T Cells for Relapsed or Refractory Non Hodgkin Lymphoma
Not yet reported Benjamin Tomlinson 31 participants Est. completion 2036-02 2 sites Stand-aloneOther conditions: Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT03441100
TCR-engineered T Cells in Solid Tumors: IMA202-101
Not yet reported Immatics US, Inc. 16 participants Est. completion 2023-03-17 6 sites Stand-aloneOther conditions: Solid Tumor, Adult, Refractory Cancer, Recurrent Cancer, CancerView official trial listing → -
Completed NCT NCT03441958
ECT-001 (UM171) Expanded Cord Blood Transplant to Treat High-risk Multiple Myeloma
Not yet reported, Not yet reported Ciusss de L'Est de l'Île de Montréal 19 participants Est. completion 2025-10-17 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Withdrawn NCT NCT03446638
iCare 2: Personalized Genomic Mutation Informed Treatment of Patients With Myelodysplastic Syndromes
Not yet reported University of Florida Est. completion 2022-09 1 siteOther conditions: Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT03448393
CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults With Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Not yet reported National Cancer Institute (NCI) 54 participants Est. completion 2025-01-13 1 site Stand-aloneOther conditions: Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, B Cell, B-Cell Lymphoma, B-Cell Leukemia, Acute Lymphoid Leukemia, B-Non Hodgkin Lymphoma, B-NHL, B-All, Acute Lymphoblastic Leukemia, Acute Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT03448978
Autologous CD8+ T-cells Expressing an Anti-BCMA CAR in Patients With Myeloma
Not yet reported Cartesian Therapeutics 32 participants Est. completion 2021-06-03 3 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT03449108
LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas
Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2027-04-30 1 site Stand-aloneObstructive sleep apnea Other conditions: Bone Sarcoma, Giant Cell Tumor of Bone, Malignancy in Giant Cell Tumor of Bone, Malignant Solid Neoplasm, Platinum-Resistant Ovarian Carcinoma, Poorly Differentiated Thyroid Gland Carcinoma, Recurrent Ovarian Carcinoma, Soft Tissue Sarcoma, Thyroid Gland Anaplastic Carcinoma, Thyroid Gland Squamous Cell Carcinoma, Undifferentiated High Grade Pleomorphic Sarcoma of Bone, Triple Negative Breast CancerView official trial listing → -
Completed NCT NCT03455504
Venetoclax Add in Combination With Fludarabine, Cyratabine and Idarubicine in Induction for Acute Myelid Leukemia
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 124 participants Est. completion 2026-07-15 22 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT03456817
HIgh Dose Thymoglobulin Instead of Cyclosporine With a Low Dose of Thymoglobulin for GVHD Prophylaxis
Not yet reported AHS Cancer Control Alberta 68 participants Est. completion 2025-05-31 1 site Stand-aloneOther conditions: Graft-versus-host-disease, RelapseView official trial listing → -
Completed NCT NCT03462316
NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma
Not yet reported Sun Yat-sen University 2 participants Est. completion 2026-04-15 1 site Stand-aloneOther conditions: Bone Sarcoma, Soft Tissue SarcomaView official trial listing → -
Completed NCT NCT03466320
DEPLETHINK - LymphoDEPLEtion and THerapeutic Immunotherapy With NKR-2
Not yet reported, Not yet reported Celyad Oncology SA 21 participants Est. completion 2021-02-01 7 sites Stand-aloneOther conditions: AML, MDSView official trial listing → -
Status unknown NCT NCT03467256
CD19 T-CAR for Treatment of Children and Young Adults With r/r B-ALL
Not yet reported, Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 18 participants Est. completion 2025-10-15 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic Leukemia, Acute Lymphocytic Leukemia, PediatricView official trial listing → -
Active, not recruiting NCT NCT03467516
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma
Not yet reported Udai Kammula 34 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Uveal Neoplasms, Melanoma, UvealView official trial listing → -
Completed NCT NCT03475134
TIL-ACT After NMA Chemo with IL-2 and Nivo Rescue in Metastatic Melanoma (mMEL)
Not yet reported Centre Hospitalier Universitaire Vaudois 18 participants Est. completion 2024-06-06 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT03480360
Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expression
Not yet reported Dartmouth-Hitchcock Medical Center 21 participants Est. completion 2025-10-17 1 siteOther conditions: Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia, Chronic Myeloid Leukemia, Myelodysplasia, Myeloproliferative Disorder, Myelofibrosis, Lymphoma, Lymphoma, Non-Hodgkin, Plasma Cell DisorderView official trial listing → -
Suspended NCT NCT03494569
Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome
Not yet reported City of Hope Medical Center 36 participants Est. completion 2027-09-07 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia, Acute Myeloid Leukemia in Remission, Hematopoietic Cell Transplantation Recipient, Minimal Residual Disease, Myelodysplastic Syndrome, Secondary Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT03497533
Treatment of Refractory/Relapsed Non-Hodgkin Lymphoma With TriCAR-T_CD19
Not yet reported, Not yet reported Timmune Biotech Inc. 6 participants Est. completion 2020-12-31 1 site Stand-aloneOther conditions: Non-hodgkin Lymphoma,B CellView official trial listing → -
Terminated NCT NCT03502577
BCMA-Specific CAR T-Cells Combined With a Gamma Secretase Inhibitor (JSMD194) to Treat Relapsed or Persistent Multiple Myeloma
Not yet reported Fred Hutchinson Cancer Center 19 participants Est. completion 2022-04-20 1 site Stand-aloneOther conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell MyelomaView official trial listing → -
Terminated NCT NCT03504410
Efficacy/Safety of CPI-613 in Combination With HD Cyt. and Mito. vs HD Cyt. and Mito. in Older Patients With R/R AML
Not yet reported Cornerstone Pharmaceuticals 200 participants Est. completion 2022-01-19 60 sitesOther conditions: Relapsed/Refractory Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03513328
Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation
Not yet reported, Not yet reported University of Florida 6 participants Est. completion 2023-02-19 1 site Stand-aloneOther conditions: Bone Marrow Failure Syndrome, Thalassemia, Sickle Cell Disease, Diamond Blackfan Anemia, Acquired Neutropenia in Newborn, Acquired Anemia Hemolytic, Acquired Thrombocytopenia, Hemophagocytic Lymphohistiocytoses, Wiskott-Aldrich Syndrome, Chronic Granulomatous Disease, Common Variable Immunodeficiency, X-linked Lymphoproliferative Disease, Severe Combined Immunodeficiency, Hurler Syndrome, Mannosidosis, AdrenoleukodystrophyView official trial listing → -
Completed NCT NCT03524235
Haploidentical Stem Cell Transplant with Prophylactic Natural Killer DLI for Lymphoma, Multiple Myeloma, and CLL
Not yet reported Noah Merin 20 participants Est. completion 2024-11-06 1 site Stand-aloneOther conditions: Multiple Myeloma, CLL, Chronic Lymphocytic Leukemia, Lymphoma, Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT03526185
A Pilot Study Using Short-Term Cultured Anti-Tumor Autologous Lymphocytes
Not yet reported Yale University 6 participants Est. completion 2020-12-01 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Status unknown NCT NCT03528421
Assessment of Safety and Efficacy of IM19 for Relapsed or Refractory NHL Patients
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 30 participants Est. completion 2020-05 1 site Stand-aloneOther conditions: Non Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT03530085
Dec+Flu+Bu Conditioning Regimen for Elderly AML in CR Undergoing Allo-HSCT
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 60 participants Est. completion 2022-04-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Allogeneic Hematopoietic Stem Cell Transplantation, Conditioning, ElderlyView official trial listing → -
Active, not recruiting NCT NCT03531736
T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia
Not yet reported Memorial Sloan Kettering Cancer Center 17 participants Est. completion 2027-05 2 sites Stand-aloneOther conditions: Myeloid DiseasesView official trial listing → -
Completed NCT NCT03539406
Intraperitoneal Infusion of ex Vivo-cultured Allogeneic NK Cells in Recurrent Ovarian Carcinoma Patients
Not yet reported Radboud University Medical Center 11 participants Est. completion 2023-09-01 1 site Stand-aloneOther conditions: Recurrent Ovarian Carcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Primary Peritoneal CarcinomaView official trial listing → -
Status unknown NCT NCT03540303
Cytoplasmic Activated PD-1 CAR T Cells in Refractory/Relapsed B Cell Lymphoma
Not yet reported Henan Cancer Hospital 15 participants Est. completion 2020-04-30 1 site Stand-aloneOther conditions: Relapsed Non Hodgkin LymphomaView official trial listing → -
Active, not recruiting NCT NCT03549442
Up-front CART-BCMA With or Without huCART19 in High-risk Multiple Myeloma
Not yet reported University of Pennsylvania 40 participants Est. completion 2036-03 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Withdrawn NCT NCT03560908
Dasatinib Combined With Chemotherapy in Relapsed t(8;21) Acute Myeloid Leukemia With KIT D816 Mutation
Not yet reported Institute of Hematology & Blood Diseases Hospital, China Est. completion 2021-12-31 1 site Stand-aloneOther conditions: Relapsed AML, T(8;21), C-KIT MutationView official trial listing → -
Completed NCT NCT03570892
Tisagenlecleucel in Adult Patients With Aggressive B-cell Non-Hodgkin Lymphoma
Not yet reported Novartis Pharmaceuticals 330 participants Est. completion 2026-02-03 67 sites Stand-aloneOther conditions: Non-Hodgkin LymphomaView official trial listing → -
Active, not recruiting NCT NCT03573700
Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported St. Jude Children's Research Hospital 24 participants Est. completion 2027-07-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia, RefractoryView official trial listing → -
Completed NCT NCT03575351
A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas
Not yet reported Celgene 184 participants Est. completion 2023-10-23 54 sites Stand-aloneOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Terminated NCT NCT03579888
CD19-Specific T Cells Post AlloSCT
Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2021-05-27 1 site Stand-aloneOther conditions: B Acute Lymphoblastic Leukemia With t(v;11q23.3); KMT2A Rearranged, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Recurrent Mantle Cell Lymphoma, Recurrent Non-Hodgkin Lymphoma, Recurrent Ph-Like Acute Lymphoblastic Leukemia, Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory B Acute Lymphoblastic Leukemia, Refractory Chronic Lymphocytic Leukemia, Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Refractory Mantle Cell Lymphoma, Refractory Non-Hodgkin Lymphoma, Refractory Ph-Like Acute Lymphoblastic Leukemia, Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma, Refractory Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT03585517
Safety and Efficacy Evaluation of IM23 CAR-T Cells (IM23CAR-T)
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 10 participants Est. completion 2020-10-01 1 site Stand-aloneOther conditions: AMLView official trial listing → -
Terminated NCT NCT03585764
MOv19-BBz CAR T Cells in aFR Expressing Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Not yet reported University of Pennsylvania 46 participants Est. completion 2024-03-26 1 site Stand-aloneOther conditions: Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal CarcinomaView official trial listing → -
Terminated NCT NCT03590574
Phase I/II Study Evaluating AUTO4 in Patients With T Cell Receptor Beta Constant (TRBC)1 Positive T Cell Lymphoma
Not yet reported, Not yet reported Autolus Limited 20 participants Est. completion 2024-12-12 5 sites Stand-aloneOther conditions: T Cell Non-Hodgkin Lymphoma, Peripheral T-Cell Lymphoma, Not Otherwise Specified, Angioimmunoblastic T-cell Lymphoma, Anaplastic Large Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT03591510
A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML
Not yet reported Novartis Pharmaceuticals 22 participants Est. completion 2029-05-18 15 sites Stand-aloneOther conditions: FLT3-mutated Acute Myeloid LeukemiaView official trial listing → -
No Longer Available NCT NCT03594162
Compassionate Use of CAR T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch
UNC Lineberger Comprehensive Cancer Center 1 siteOther conditions: Acute Lymphoblastic Leukemia, Immune System Diseases, Immunoproliferative DisordersView official trial listing → -
Active, not recruiting NCT NCT03597594
Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)
Not yet reported, Not yet reported St. Jude Children's Research Hospital 4 participants Est. completion 2028-07-01 1 siteOther conditions: Severe Combined ImmunodeficiencyView official trial listing → -
Status unknown NCT NCT03600558
Efficacy of FLAG Regimen for the Treatment of Patients With AML
Tianjin Medical University General Hospital 60 participants Est. completion 2020-07 1 siteOther conditions: Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, AcuteView official trial listing → -
Terminated NCT NCT03600909
A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia
Not yet reported Memorial Sloan Kettering Cancer Center 3 participants Est. completion 2021-04-09 3 sites Stand-aloneOther conditions: Fanconi Anemia, Myelodysplastic Syndrome (MDS), Acute Myelogenous Leukemia (AML)View official trial listing → -
Active, not recruiting NCT NCT03602157
Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL
Not yet reported UNC Lineberger Comprehensive Cancer Center 43 participants Est. completion 2039-11-04 1 site Stand-aloneOther conditions: Lymphoma, Immune System Diseases, Immunoproliferative Disorders, Lymphatic Diseases, Lymphoproliferative Disorders, Neoplasms, Cutaneous Lymphoma, Cutaneous Anaplastic Large Cell Lymphoma, Mycosis Fungoides, Sezary Syndrome, Lymphomatoid Papulosis, Cutaneous T Cell Lymphoma, Gray Zone LymphomaView official trial listing → -
Completed NCT NCT03602612
T Cells Expressing a Novel Fully-Human Anti-BCMA CAR for Treating Multiple Myeloma
Not yet reported National Cancer Institute (NCI) 35 participants Est. completion 2026-04-23 1 site Stand-aloneOther conditions: Myeloma-Multiple, Myeloma, Plasma-CellView official trial listing → -
Withdrawn NCT NCT03602898
Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell Transplantation
Not yet reported Fred Hutchinson Cancer Center Est. completion 2023-09-17 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia in Remission, Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid System Neoplasm, Myelodysplastic Syndrome, Myelofibrosis, Myeloproliferative Neoplasm, Recurrent Acute Myeloid Leukemia, Recurrent Hodgkin Lymphoma, Recurrent Non-Hodgkin Lymphoma, Refractory Acute Myeloid Leukemia, Therapy-Related Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03609814
Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)
University of California, San Francisco 30 participants Est. completion 2020-06-30 1 siteOther conditions: Hematologic Malignancies, Nonmalignant Diseases, Immunodeficiencies, Hemoglobinopathies, Genetic Inborn Errors of Metabolism, Fanconi's Anemia, Thalassemia, Sickle Cell DiseaseView official trial listing → -
Terminated NCT NCT03610490
Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma
Not yet reported M.D. Anderson Cancer Center 16 participants Est. completion 2024-08-21 1 site Stand-aloneObstructive sleep apnea Other conditions: Malignant Solid Neoplasm, Metastatic Colorectal Adenocarcinoma, Metastatic Ovarian Carcinoma, Metastatic Pancreatic Ductal Adenocarcinoma, Platinum-Resistant Ovarian Carcinoma, Recurrent High Grade Ovarian Serous Adenocarcinoma, Refractory Colorectal Carcinoma, Stage IV Colorectal Cancer AJCC v8, Stage IVA Colorectal Cancer AJCC v8, Stage IVB Colorectal Cancer AJCC v8, Stage IVC Colorectal Cancer AJCC v8View official trial listing → -
Completed NCT NCT03610724
Phase II Open Label Trial to Determine Safety & Efficacy of Tisagenlecleucel in Pediatric Non-Hodgkin Lymphoma Patients
Not yet reported Novartis Pharmaceuticals 34 participants Est. completion 2023-04-26 26 sites Stand-aloneOther conditions: Non-Hodgkin LymphomaView official trial listing → -
Active, not recruiting NCT NCT03613532
Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN
Not yet reported Jacqueline Garcia, MD 102 participants Est. completion 2030-03-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), MDS/Myeloproliferative Neoplasm-unclassifiable (MDS/MPN-unclassifiable), Hematopoietic Stem Cell TransplantView official trial listing → -
Terminated NCT NCT03615105
Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched Donors
Not yet reported Memorial Sloan Kettering Cancer Center 9 participants Est. completion 2024-03-06 1 site Stand-aloneOther conditions: Acute Lymphoid Leukemia (ALL), Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT03615144
TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated Donors
Not yet reported Memorial Sloan Kettering Cancer Center 1 participants Est. completion 2020-11-13 1 siteOther conditions: Non-Malignant Hematologic DisordersView official trial listing → -
Status unknown NCT NCT03615313
PD-1 Antibody Expressing mesoCAR-T Cells for Mesothelin Positive Advanced Solid Tumor
Not yet reported, Not yet reported Shanghai Cell Therapy Research Institute 50 participants Est. completion 2020-12-03 1 site Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Terminated NCT NCT03616470
Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported GlycoMimetics Incorporated 388 participants Est. completion 2024-03-31 70 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03622788
Cytokine-Treated Veto Cells in Treating Patients With Hematologic Malignancies Following Stem Cell Transplant
Not yet reported, Not yet reported M.D. Anderson Cancer Center 16 participants Est. completion 2027-12-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Aplastic Anemia, Bone Marrow Failure, Chronic Lymphocytic Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Follicular Lymphoma, Hodgkin Lymphoma, Mantle Cell Lymphoma, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Non-Hodgkin Lymphoma, Plasma Cell MyelomaView official trial listing → -
Terminated NCT NCT03624036
Study to Evaluate the Safety and Tolerability of Brexucabtagene Autoleucel (KTE-X19) in People With Relapsed/Refractory Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
Not yet reported Kite, A Gilead Company 16 participants Est. completion 2022-11-18 22 sites Stand-aloneOther conditions: Relapsed/Refractory Chronic Lymphocytic Leukemia and Relapsed/Refractory Small Lymphocytic LymphomaView official trial listing → -
Status unknown NCT NCT03633773
Safety and Efficacy Evaluation of MUC-1 CART in the Treatment of Intrahepatic Cholangiocarcinoma
Not yet reported, Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 9 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Intrahepatic CholangiocarcinomaView official trial listing → -
Status unknown NCT NCT03638206
Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies
Not yet reported, Not yet reported Shenzhen BinDeBio Ltd. 73 participants Est. completion 2023-03-01 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic Leukemia, Lymphoma, Myeloid Leukemia, Multiple Myeloma, Hepatoma, Gastric Cancer, Pancreatic Cancer, Mesothelioma, Colorectal Cancer, Esophagus Cancer, Lung Cancer, Glioma, Melanoma, Synovial Sarcoma, Ovarian Cancer, Renal CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03642626
MT2017-45: CAR-T Cell Therapy for Heme Malignancies
Not yet reported Masonic Cancer Center, University of Minnesota 150 participants Est. completion 2028-06-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Large B-cell LymphomaView official trial listing → -
Status unknown NCT NCT03648697
EBV-TCR-T(YT-E001)for Patients With EBV-positive Recurrent or Metastatic NPC
Not yet reported Fujian Cancer Hospital 20 participants Est. completion 2021-10-10 1 site Stand-aloneOther conditions: Nasopharyngeal CarcinomaView official trial listing → -
Status unknown NCT NCT03658785
Immunotherapy for the Treatment of Advanced Solid Tumor
Not yet reported, Not yet reported Tongji Hospital 40 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Recurrence Tumor, Metastatic Cancer, Solid TumorView official trial listing → -
Completed NCT NCT03661515
Selinexor (KPT-330) Plus FLAG-Ida for the Treatment of Relapsing/Refractory AML
Not yet reported PETHEMA Foundation 16 participants Est. completion 2019-10-15 4 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT03664661
BCMA-CAR-T in Relapsed/Refractory Multiple Myeloma
Not yet reported Henan Cancer Hospital 15 participants Est. completion 2020-04-30 1 site Stand-aloneOther conditions: Relapsed/Refractory MyelomaView official trial listing → -
Active, not recruiting NCT NCT03672318
Study of ATLCAR.CD138 Cells for Relapsed/Refractory Multiple Myeloma
Not yet reported UNC Lineberger Comprehensive Cancer Center 25 participants Est. completion 2039-08-18 1 site Stand-aloneOther conditions: Multiple Myeloma, Immune System DiseasesView official trial listing → -
Terminated NCT NCT03672851
Study Evaluating Safety and Efficacy of CAR-T Cells Targeting CD123 in Patients With Acute Leukemia
Not yet reported Second Affiliated Hospital of Xi'an Jiaotong University 2 participants Est. completion 2019-07-31 1 site Stand-aloneOther conditions: Acute Leukemia, Acute Leukemia in Relapse, Acute Myeloid Leukemia, Relapsed or Refractory Acute LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03674411
Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy
Not yet reported Masonic Cancer Center, University of Minnesota 22 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, Biphenotypic/Undifferentiated Leukemia, Chronic Myelogenous Leukemia, Myelodysplasia, Relapsed Large Cell Lymphoma, Mantle Cell Lymphoma, Hodgkin Lymphoma, Burkitt Lymphoma, Relapsed T-Cell Lymphoma, Lymphoplasmacytic LymphomaView official trial listing → -
Status unknown NCT NCT03687463
Modified Post-Transplant Cyclophosphamide Regimen for Children With Juvenile Myelomonocytic Leukemia
Capital Research Institute of Pediatrics 6 participants Est. completion 2020-04-10Other conditions: Hematopoietic System--CancerView official trial listing → -
Active, not recruiting NCT NCT03690011
Cell Therapy for High Risk T-Cell Malignancies Using CD7-Specific CAR Expressed On Autologous T Cells
Not yet reported Baylor College of Medicine 45 participants Est. completion 2041-03-31 2 sites Stand-aloneOther conditions: T-cell Acute Lymphoblastic Lymphoma, T-non-Hodgkin Lymphoma, T-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT03692663
Study of Anti-PSMA CAR NK Cell (TABP EIC) in Metastatic Castration-Resistant Prostate Cancer
Not yet reported Allife Medical Science and Technology Co., Ltd. 9 participants Est. completion 2024-06 1 site Stand-aloneOther conditions: Metastatic Castration-resistant Prostate CancerView official trial listing → -
Terminated NCT NCT03696537
IMRT-TMI With Fludarabine as Myeloablative Conditioning for Allogeneic HSCT
Not yet reported Naoyuki G. Saito, M.D., Ph.D. 6 participants Est. completion 2021-04-13 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Acute Lymphocytic Leukemia, Myelodysplastic SyndromesView official trial listing → -
Withdrawn NCT NCT03697824
Clinical Trial of Safety, Tolerability and Antitumor Activity of Genetically Engineered T Cells in Combination With Anti-Cancer Agents in Relapsed and Refractory Synovial Sarcoma Expressing New York Esophageal Antigen-1 (NY-ESO-1) and/or LAGE-1a
Not yet reported GlaxoSmithKline Est. completion 2022-07-18 Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Terminated NCT NCT03704298
Safety and Efficacy of Axicabtagene Ciloleucel in Combination With Utomilumab in Adults With Refractory Large B-cell Lymphoma
Not yet reported Kite, A Gilead Company 15 participants Est. completion 2022-12-15 5 sites Stand-aloneOther conditions: Relapsed/Refractory Large B-cell LymphomaView official trial listing → -
Status unknown NCT NCT03706547
Anti-CD19/BCMA Bispecific CAR-T Cell Therapy for R/R MM
Not yet reported Peng Liu 20 participants Est. completion 2021-12 1 site Stand-aloneOther conditions: Multiple Myeloma in Relapse, Multiple Myeloma ProgressionView official trial listing → -
Suspended NCT NCT03710421
CS1-CAR T Therapy Following Chemotherapy in Treating Patients With Relapsed or Refractory CS1 Positive Multiple Myeloma
Not yet reported City of Hope Medical Center 30 participants Est. completion 2027-02-23 1 site Stand-aloneOther conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell MyelomaView official trial listing → -
Status unknown NCT NCT03711864
Safety and Efficacy of IM21 Car-t Cells in Patients With Recurrent or Refractory BCMA Positive Multiple Myeloma
Not yet reported Peking Union Medical College Hospital 15 participants Est. completion 2021-12-20 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT03716856
Clinical Study of CAR-BCMA T in Patients With Refractory or Relapsed Multiple Myeloma
Not yet reported First Affiliated Hospital of Zhejiang University 11 participants Est. completion 2023-06-23 1 site Stand-aloneOther conditions: Refractory or Relapsed Multiple MyelomaView official trial listing → -
Status unknown NCT NCT03720496
Treatment of Refractory/Relapsed Non-Hodgkin Lymphoma With CD19-TriCART Cell Therapy
Not yet reported Timmune Biotech Inc. 6 participants Est. completion 2021-12-01 1 site Stand-aloneOther conditions: Non-hodgkin Lymphoma,B CellView official trial listing → -
Terminated NCT NCT03743246
A Study to Evaluate the Safety and Efficacy of JCAR017 in Pediatric Subjects With Relapsed/Refractory (r/r) B-cell Acute Lymphoblastic Leukemia (B-ALL) and B-cell Non-Hodgkin Lymphoma (B-NHL)
Not yet reported, Not yet reported Celgene 21 participants Est. completion 2024-01-26 19 sites Stand-aloneOther conditions: Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Non-HodgkinView official trial listing → -
Terminated NCT NCT03745326
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
Not yet reported, Not yet reported National Cancer Institute (NCI) 5 participants Est. completion 2022-08-23 1 site Stand-aloneOther conditions: Gastrointestinal Cancer, Pancreatic Cancer, Gastric Cancer, Colon Cancer, Rectal CancerView official trial listing → -
Suspended NCT NCT03752541
Efficacy and Safety Evaluation of BCMA-UCART
Not yet reported Bioray Laboratories 20 participants Est. completion 2023-11-20 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT03754933
Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck Cancer
Not yet reported, Not yet reported GeoVax, Inc. 10 participants Est. completion 2024-12-31 3 sites Stand-aloneOther conditions: Recurrent Head and Neck CancerView official trial listing → -
Completed NCT NCT03761056
Study to Evaluate the Efficacy and Safety of Axicabtagene Ciloleucel as First-Line Therapy in Participants With High-Risk Large B-Cell Lymphoma
Not yet reported Kite, A Gilead Company 42 participants Est. completion 2023-10-12 7 sites Stand-aloneOther conditions: B-cell LymphomaView official trial listing → -
Terminated NCT NCT03766126
Lentivirally Redirected CD123 Autologous T Cells in AML
Not yet reported University of Pennsylvania 22 participants Est. completion 2026-03-05 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia, Adult, Acute Myeloid Leukemia, RefractoryView official trial listing → -
Status unknown NCT NCT03767725
Anti-BCMA or/and Anti-CD19 CART Cells Treatment of Relapsed Multiple Myeloma
Not yet reported Shenzhen Second People's Hospital 10 participants Est. completion 2021-09-01 1 site Stand-aloneOther conditions: Multiple Myeloma in RelapseView official trial listing → -
Active, not recruiting NCT NCT03774654
CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR)
Not yet reported Baylor College of Medicine 13 participants Est. completion 2040-05-05 2 sites Stand-aloneOther conditions: Refractory B-Cell Non-Hodgkin Lymphoma, Refractory B-Cell Small Lymphocytic Lymphoma, Relapsed Adult ALL, Relapsed CLL, Relapsed Non Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT03778619
MG4101 Plus Rituximab Including Lymphodepletion in Patient With r/r NHL B-cell Origin
Not yet reported, Not yet reported GC Cell Corporation 9 participants Est. completion 2020-10-30 3 sites Stand-aloneOther conditions: Relapsed Non Hodgkin Lymphoma, Refractory Non-Hodgkin LymphomaView official trial listing → -
Active, not recruiting NCT NCT03779854
Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant
Not yet reported Fred Hutchinson Cancer Center 45 participants Est. completion 2027-08-31 9 sites Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Leukemia, Acute Leukemia of Ambiguous Lineage, Acute Lymphoblastic Leukemia, Acute Undifferentiated Leukemia, Allogeneic Hematopoietic Stem Cell Transplantation Recipient, Blastic Plasmacytoid Dendritic Cell Neoplasm, Blasts Under 25 Percent of Bone Marrow Nucleated Cells, Blasts Under 5 Percent of Bone Marrow Nucleated Cells, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome With Excess Blasts-1, Myelodysplastic Syndrome/Acute Myeloid Leukemia, Burkitt Leukemia, Chronic Monocytic Leukemia, Lymphoblastic Lymphoma, Mast Cell Leukemia, Myeloproliferative NeoplasmView official trial listing → -
Completed NCT NCT03790072
Ex-vivo Expanded γδ T-lymphocytes (OmnImmune®) in Patients With Acute Myeloid Leukaemia (AML)
Not yet reported TC Biopharm 10 participants Est. completion 2021-03-26 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT03790891
Treatment of Non-Hodgkin Lymphoma With CD19-TriCAR-T/SILK Cell Therapy
Not yet reported Timmune Biotech Inc. 12 participants Est. completion 2022-01-01 3 sites Stand-aloneOther conditions: Non-Hodgkin LymphomaView official trial listing → -
Active, not recruiting NCT NCT03793478
Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood
Not yet reported, Not yet reported Daiichi Sankyo 65 participants Est. completion 2027-05-01 27 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT03799913
MESO-CAR T Cells Therapy for Relapsed and Refractory Ovarian Cancer
Not yet reported Zhejiang University 20 participants Est. completion 2022-04 1 site Stand-aloneOther conditions: Ovarian CancerView official trial listing → -
Active, not recruiting NCT NCT03801083
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract Cancers
Not yet reported Udai Kammula 4 participants Est. completion 2031-01-31 1 site Stand-aloneOther conditions: Biliary Tract Cancer, Cholangiocarcinoma, Biliary Tract NeoplasmsView official trial listing → -
Completed NCT NCT03813147
Pevonedistat, Azacitidine, Fludarabine Phosphate, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2023-12-31 19 sites Stand-aloneOther conditions: Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Status unknown NCT NCT03814447
The Fourth Generation CART-cell Therapy for Refractory-Relapsed Ovarian Cancer
Not yet reported Shanghai 6th People's Hospital 10 participants Est. completion 2023-01 1 site Stand-aloneOther conditions: Ovarian CancerView official trial listing → -
Active, not recruiting NCT NCT03818763
Gene Therapy Trial for Platelet Derived Factor VIII Production in Hemophilia A
Not yet reported Medical College of Wisconsin 5 participants Est. completion 2033-05-01 1 site Stand-aloneOther conditions: Hemophilia AView official trial listing → -
Active, not recruiting NCT NCT03821610
A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC)
Not yet reported University of Birmingham 242 participants Est. completion 2027-11-22 22 sitesOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT03821987
Risk Stratification Directed Conditioning Regimen for Haploidentical HSCT in SAA
Not yet reported Peking University People's Hospital 55 participants Est. completion 2022-03-30 1 site Stand-aloneOther conditions: Aplastic Anemia, Stem Cell Transplant Complications, Engraft FailureView official trial listing → -
Status unknown NCT NCT03823365
Blinatumomab Expanded T-cells (BET) in Indolent Non-Hodgkin Lymphomas/Chronic Lymphocytic Leukemia
Not yet reported A.O. Ospedale Papa Giovanni XXIII 19 participants Est. completion 2022-11 1 siteOther conditions: Indolent Non-Hodgkin Lymphomas/Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT03832127
Evaluation of PET 18F-Fludarabine for the Initial Assessment and End-treatment of Symptomatic Multiple Myeloma Patients
Not yet reported Nantes University Hospital 35 participants Est. completion 2026-09-09 7 sites Stand-aloneOther conditions: MyelomaView official trial listing → -
Completed NCT NCT03841110
FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors
Not yet reported Fate Therapeutics 37 participants Est. completion 2022-11-15 4 sites Stand-aloneObstructive sleep apnea Other conditions: Advanced Solid Tumors, Lymphoma, Gastric Cancer, Colorectal Cancer, Head and Neck Cancer, Squamous Cell Carcinoma, EGFR Positive Solid Tumor, HER2-positive Breast Cancer, Hepatocellular Carcinoma, Small Cell Lung Cancer, Renal Cell Carcinoma, Pancreas Cancer, Melanoma, NSCLC, Urothelial Carcinoma, Cervical Cancer, Merkel Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03849651
TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies
Not yet reported St. Jude Children's Research Hospital 69 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia (ALL), Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS), NK-Cell Leukemia, Hodgkin Lymphoma, Non Hodgkin Lymphoma (NHL), Juvenile Myelomonocytic Leukemia (JMML), Chronic Myeloid Leukemia (CML)View official trial listing → -
Completed NCT NCT03851146
A Study of Anti-Lewis Y Chimeric Antigen Receptor-T Cells (LeY-CAR-T) in Patients With Solid Tumours
Not yet reported Peter MacCallum Cancer Centre, Australia 20 participants Est. completion 2022-04-01 1 site Stand-aloneOther conditions: Advanced CancerView official trial listing → -
Completed NCT NCT03852498
A Clinical Study to Assess the Efficacy and Safety of Gene Therapy for the Treatment of Cerebral Adrenoleukodystrophy (CALD)
Not yet reported Genetix Biotherapeutics Inc. 35 participants Est. completion 2023-07-24 8 sites Stand-aloneOther conditions: Cerebral Adrenoleukodystrophy (CALD)View official trial listing → -
Terminated NCT NCT03856216
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation
Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2025-10-13 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia, Lymphocytic Neoplasm, LymphomaView official trial listing → -
Terminated NCT NCT03860844
Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia
Not yet reported Sanofi 67 participants Est. completion 2023-05-26 41 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT03873805
PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate Cancer
Not yet reported City of Hope Medical Center 14 participants Est. completion 2027-03-18 1 site Stand-aloneOther conditions: Castration-Resistant Prostate Carcinoma, Metastatic Prostate Carcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8View official trial listing → -
Completed NCT NCT03874897
Chimeric Antigen Receptor T Cells Targeting claudin18.2 in Solid Tumors.
Not yet reported Peking University 134 participants Est. completion 2024-01-26 3 sites Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Status unknown NCT NCT03881761
CD19/20 Bispecific Nanobody-derived CAR-T Cells in B Cell Lymphoma
Not yet reported Henan Cancer Hospital 50 participants Est. completion 2022-01-31 2 sites Stand-aloneOther conditions: B-Cell Lymphoma Stage I, Refractory, RelapsedView official trial listing → -
Status unknown NCT NCT03881774
Cord Blood Derived CAR-T Cells in Refractory/Relapsed B Cell Malignancies
Not yet reported Henan Cancer Hospital 20 participants Est. completion 2022-01-31 2 sites Stand-aloneOther conditions: Refractory, Relapsed, B Cell Lymphoma, B Cell LeukemiaView official trial listing → -
Completed NCT NCT03882203
CLAGE Sequential With Flu-Bu Conditioning for Refractory Acute Leukemia
Not yet reported Shanghai Jiao Tong University School of Medicine 18 participants Est. completion 2022-12-30 1 site Stand-aloneOther conditions: Refractory Hematologic Cancer, Allogeneic Stem Cell TransplantationView official trial listing → -
Completed NCT NCT03885947
VPA Expanded UCB Transplantation for Treatment of Patients With Hematological Malignancies
Not yet reported Alla Keyzner 7 participants Est. completion 2021-03-10 1 site Stand-aloneOther conditions: Hematological Malignancy, Acute Leukemia in Remission, Acute Lymphoblastic Leukemia in Remission, Myelodysplastic Syndromes, Non-Hodgkin Lymphoma, Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT03890198
A Phase 1 Study of LCAR-C182A Cells in the Treatment of Advanced Gastric Cancer and Pancreatic Ductal Adenocarcinoma
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 2 participants Est. completion 2020-03-06 1 site Stand-aloneOther conditions: Gastric Cancer, Pancreatic Ductal AdenocarcinomaView official trial listing → -
Completed NCT NCT03902665
Up-front Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia Patients Aged 65-75
Not yet reported Fondazione Policlinico Universitario Agostino Gemelli IRCCS 19 participants Est. completion 2024-06-30 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, AdultView official trial listing → -
Active, not recruiting NCT NCT03907852
Phase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing Cancer
Not yet reported, Not yet reported TCR2 Therapeutics 57 participants Est. completion 2028-11-02 11 sites Stand-aloneOther conditions: Mesothelioma, Mesothelioma, Malignant, Mesothelioma; Pleura, Mesotheliomas Pleural, Mesothelioma Peritoneum, Cholangiocarcinoma, Cholangiocarcinoma Recurrent, Ovarian Cancer, Non Small Cell Lung Cancer, Non Small Cell Lung Cancer Metastatic, High Grade Ovarian Serous AdenocarcinomaView official trial listing → -
Status unknown NCT NCT03910842
Treatment of Children CD19+ Leukemia and Non-Hodgkin Lymphoma With CD19-TriCAR-T/SILK Cell Therapy
Not yet reported Timmune Biotech Inc. 12 participants Est. completion 2022-10-15 1 site Stand-aloneOther conditions: Non-Hodgkin Lymphoma of Intestine, LeukemiaView official trial listing → -
Terminated NCT NCT03912831
Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers
Not yet reported Gilead Sciences 8 participants Est. completion 2022-02-18 9 sites Stand-aloneOther conditions: Human Papillomavirus (HPV) 16+ Relapsed/Refractory CancerView official trial listing → -
Active, not recruiting NCT NCT03913026
UM171 Expanded Cord Blood In Patients With High-Risk Acute Leukemia/Myelodysplasia
Not yet reported Ciusss de L'Est de l'Île de Montréal 30 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: High Risk Hematologic Malignancy, Cord Blood TransplantView official trial listing → -
No Longer Available NCT NCT03914885
Compassionate Use Re-Infusion of ATLCAR.CD30
UNC Lineberger Comprehensive Cancer Center 1 siteOther conditions: Hodgkin Lymphoma, AdultView official trial listing → -
Status unknown NCT NCT03916679
MESO-CAR T Cells Therapy for Relapsed and Refractory Epithelial Ovarian Cancer
Not yet reported, Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 20 participants Est. completion 2023-04-20 1 siteOther conditions: Ovarian CancerView official trial listing → -
Active, not recruiting NCT NCT03919240
CAR-T Cell Therapy Targeting to CD19 for R/R ALL
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 196 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia With Failed RemissionView official trial listing → -
Completed NCT NCT03919526
Anti-CD19/CD22 Bispecific Chimeric Antigen Receptor(CAR)-T Cell Therapy for Measurable Residual Disease(MRD) Positive ALL
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 19 participants Est. completion 2023-11-01 1 site Stand-aloneOther conditions: MRD-positive, Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT03926624
Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage
Not yet reported Delta-Fly Pharma, Inc. 167 participants Est. completion 2026-01-07 39 sitesOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Withdrawn NCT NCT03935347
Adoptive Cell Therapy With (LN-145) in Combination With Pembrolizumab in Treating Patients With Unresectable or Metastatic Transitional Cell Cancer Who Have Failed Cisplatin-Based Chemotherapy
Not yet reported Roswell Park Cancer Institute Est. completion 2023-05-01 1 site Stand-aloneOther conditions: Metastatic Bladder Urothelial Carcinoma, Metastatic Renal Pelvis Urothelial Carcinoma, Metastatic Ureter Urothelial Carcinoma, Metastatic Urethral Urothelial Carcinoma, Unresectable Renal Pelvis Urothelial Carcinoma, Unresectable Ureter Urothelial CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03935893
Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers
Not yet reported Udai Kammula 20 participants Est. completion 2038-06-30 1 site Stand-aloneObstructive sleep apnea Other conditions: Gastric Cancer, Colorectal Cancer, Pancreatic Cancer, Sarcoma, Mesothelioma, Neuroendocrine Tumors, Squamous Cell Cancer, Merkel Cell Carcinoma, Mismatch Repair DeficiencyView official trial listing → -
Completed NCT NCT03939026
Safety and Efficacy of ALLO-501 Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell or Follicular Lymphoma
Not yet reported Allogene Therapeutics 50 participants Est. completion 2025-01-28 7 sites Stand-aloneOther conditions: Relapsed/Refractory Large B Cell Lymphoma, Relapsed/Refractory Follicular LymphomaView official trial listing → -
Status unknown NCT NCT03941626
Autologous CAR-T/TCR-T Cell Immunotherapy for Solid Malignancies
Not yet reported, Not yet reported Shenzhen BinDeBio Ltd. 50 participants Est. completion 2021-12-01 1 site Stand-aloneOther conditions: Esophagus Cancer, Hepatoma, Glioma, Gastric CancerView official trial listing → -
Status unknown NCT NCT03943472
BCMA Chimeric Antigen Receptor Expressing T Cells Therapy for Relapsed/Refractory Multiple Myeloma
Not yet reported Hrain Biotechnology Co., Ltd. 10 participants Est. completion 2022-05 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT03952923
CD19-CAR-T in B-cell Malignancies Patients
Not yet reported Hebei Yanda Ludaopei Hospital 11 participants Est. completion 2021-03-31 1 site Stand-aloneOther conditions: B-cell MalignancyView official trial listing → -
Completed NCT NCT03953599
CD19-Synthetic T Cell Antigen Receptor(STAR)-T in B-cell Malignancies Patients
Not yet reported Hebei Yanda Ludaopei Hospital 18 participants Est. completion 2021-12-31 1 site Stand-aloneOther conditions: B Cell MalignancyView official trial listing → -
Status unknown NCT NCT03955601
A Novel TBI Free Conditioning Protocol for Haploidentical Transplant in Acquired Aplastic Anemia:
Not yet reported National Institute of Blood and Marrow Transplant (NIBMT), Pakistan 30 participants Est. completion 2021-06-30 1 site Stand-aloneOther conditions: Aplastic Anemia IdiopathicView official trial listing → -
Completed NCT NCT03958656
T-cells Expressing an Anti-SLAMF7 CAR for Treating Multiple Myeloma
Not yet reported National Cancer Institute (NCI) 13 participants Est. completion 2021-01-19 1 site Stand-aloneOther conditions: Myeloma-Multiple, Myeloma, Plasma-CellView official trial listing → -
Terminated NCT NCT03960060
A Study of CCT301-59 CAR T Therapy in Adult Subjects With Recurrent or Refractory Solid Tumors
Not yet reported Shanghai PerHum Therapeutics Co., Ltd. 9 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: Solid Tumor, Soft Tissue Sarcoma, Gastric Cancer, Pancreatic Cancer, Bladder CancerView official trial listing → -
Completed NCT NCT03961919
Phase II Trial in Elderly Patients With AML or MDS in Complete Remission Not Eligible for Allogenic Transplant
Not yet reported Ciceri Fabio 15 participants Est. completion 2021-12-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Transplant-Related Hematologic MalignancyView official trial listing → -
Terminated NCT NCT03963024
Treosulfan-TMI Conditioning and Rapamycin GvHD Prophylaxis Before Allo-HSCT
Not yet reported IRCCS San Raffaele 9 participants Est. completion 2019-01-31 1 site Stand-aloneOther conditions: Irradiated Bone Marrow, Transplant-Related Hematologic Malignancy, Leukemia, Acute, Multiple Myeloma, Graft Vs Host DiseaseView official trial listing → -
Active, not recruiting NCT NCT03967223
Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors
Not yet reported USWM CT, LLC 103 participants Est. completion 2028-07-31 38 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT03971799
Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported Center for International Blood and Marrow Transplant Research 52 participants Est. completion 2039-12 6 sites Stand-aloneOther conditions: Acute Myelogenous LeukemiaView official trial listing → -
Completed NCT NCT03980288
4th Generation Chimeric Antigen Receptor T Cells Targeting Glypican-3
Not yet reported Zhejiang University 6 participants Est. completion 2020-12-30 1 site Stand-aloneOther conditions: Advanced Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03983850
Optimizing PTCy Dose and Timing
Not yet reported, Not yet reported National Cancer Institute (NCI) 105 participants Est. completion 2026-10-26 1 site Stand-aloneOther conditions: Graft Versus Host Disease, Hematologic NeoplasmsView official trial listing → -
Terminated NCT NCT03992326
Adoptive Transfer Of Autologous Tumor-Infiltrating Lymphocytes in Solid Tumors
Not yet reported Centre Hospitalier Universitaire Vaudois 6 participants Est. completion 2021-03-05 1 site Stand-aloneOther conditions: Solid Tumor, AdultView official trial listing → -
Terminated NCT NCT03994705
Descartes-11 in Patients With Relapsed/Refractory Multiple Myeloma
Not yet reported Cartesian Therapeutics 20 participants Est. completion 2021-06-11 2 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT03994913
Clinical Trial to Evaluate CD19 CAR T (CT032) in Patients With Relapsed and/or Refractory Non-Hodgkin's B Cell Lymphoma
Not yet reported, Not yet reported CARsgen Therapeutics Co., Ltd. 20 participants Est. completion 2021-05-27 2 sites Stand-aloneOther conditions: Refractory B-Cell Non-Hodgkin Lymphoma, Relapsed B-cell Non-Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT04000698
Personalized Targeted Preparative Regimen Before T-depleted Allogeneic HSCT in Children With Chemoresistent Acute Leukemias
Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 25 participants Est. completion 2022-12 1 site Stand-aloneOther conditions: Refractory Acute Myeloid Leukemia, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT04002115
Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AML
Not yet reported Milton S. Hershey Medical Center 2 participants Est. completion 2022-11-07 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT04002401
Safety and Efficacy of Axicabtagene Ciloleucel in Combination With Rituximab in Participants With Refractory Large B-Cell Lymphoma
Not yet reported Kite, A Gilead Company 27 participants Est. completion 2023-01-30 14 sites Stand-aloneOther conditions: Refractory Large B-cell LymphomaView official trial listing → -
Status unknown NCT NCT04004637
CD7 CAR-T Cells for Patients With R/R CD7+ NK/T Cell Lymphoma,T-lymphoblastic Lymphoma and Acute Lymphocytic Leukemia
Not yet reported PersonGen BioTherapeutics (Suzhou) Co., Ltd. 10 participants Est. completion 2021-06-01 1 site Stand-aloneOther conditions: T-lymphoblastic Lymphoma, NK/T Cell Lymphoma, Acute Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04007029
Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia
Not yet reported Jonsson Comprehensive Cancer Center 24 participants Est. completion 2028-08-01 1 site Stand-aloneOther conditions: CD19 Positive, CD20 Positive, Recurrent Chronic Lymphocytic Leukemia, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Follicular Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma, Recurrent Small Lymphocytic Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Diffuse Large B-Cell Lymphoma, Refractory Follicular Lymphoma, Refractory Mantle Cell Lymphoma, Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma, Refractory Small Lymphocytic LymphomaView official trial listing → -
Status unknown NCT NCT04008888
a Clinical Trial of Efficacy and Safety of the Holistic Treatment of Young High-risk Multiple Myeloma Patients
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 50 participants Est. completion 2020-08-01 1 site Stand-aloneOther conditions: Multiple Myeloma, Plasma Cell Leukemia, Extramedullary Plasmacytoma, Loss of Chromosome 17p, t(14;16), t(4;14), T(14;20), 1Q21 Amplification, Complex KaryotypeView official trial listing → -
Completed NCT NCT04010968
Evaluation of Risk-Adapted and MRD-Driven Strategy for Untreated Fit Patients With Intermediate Risk Chronic Lymphocytic Leukemia
Not yet reported French Innovative Leukemia Organisation 120 participants Est. completion 2025-01-30 34 sitesOther conditions: Intermediate Risk Chronic Lymphocytic Leukemia, Fit Patients, Risk-Adapted and MRD-Driven StrategyView official trial listing → -
Status unknown NCT NCT04014894
ET019003-T Cells in Relapsed/Refractory CD19+ B-Cell Leukemia and Lymphoma
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 9 participants Est. completion 2022-07-01 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT04015336
E7 TCR Cell Induction Immunotherapy for Stage II and Stage III HPV-Associated Oropharyngeal Cancer
Not yet reported National Cancer Institute (NCI) 1 participants Est. completion 2020-07-15 1 siteOther conditions: Papillomavirus Infections, Oropharyngeal NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT04018937
Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation
Not yet reported Emory University 43 participants Est. completion 2026-11 15 sites Stand-aloneOther conditions: Sickle Cell DiseaseView official trial listing → -
Terminated NCT NCT04025216
A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers
Not yet reported Kite, A Gilead Company 16 participants Est. completion 2022-12-02 10 sites Stand-aloneOther conditions: Non-Small Cell Lung Cancer, Ovarian Cancer, Fallopian Tube Cancer, Triple Negative Breast Cancer, Multiple Myeloma, Pancreatic Ductal AdenocarcinomaView official trial listing → -
Withdrawn NCT NCT04029038
Modified Immune Cells (CD19-CD22 CAR T Cells) in Treating Patients With Recurrent or Refractory CD19 Positive, CD22 Positive Leukemia or Lymphoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center Est. completion 2022-11-16 1 site Stand-aloneOther conditions: CD19 Positive, CD22 Positive, Minimal Residual Disease, Progressive Disease, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Non-Hodgkin Lymphoma, Refractory B Acute Lymphoblastic Leukemia, Refractory Chronic Lymphocytic Leukemia, Refractory Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT04030195
Dose-escalation Study of Safety of PBCAR20A in Subjects With r/r NHL or r/r CLL/SLL
Not yet reported, Not yet reported Precision BioSciences, Inc. 18 participants Est. completion 2021-06-24 5 sites Stand-aloneOther conditions: Non-Hodgkin's Lymphoma, Relapsed, Chronic Lymphoid Leukemia in Relapse, Non-Hodgkin's Lymphoma Refractory, Chronic Lymphocytic Leukemia, Lymphoma, Non-Hodgkin, Leukemia, Lymphocytic, Chronic, B-cell Chronic Lymphocytic Leukemia, B-cell Non Hodgkin Lymphoma, Small Lymphocytic LymphomaView official trial listing → -
Status unknown NCT NCT04037566
CRISPR (HPK1) Edited CD19-specific CAR-T Cells (XYF19 CAR-T Cells) for CD19+ Leukemia or Lymphoma.
Not yet reported Xijing Hospital 40 participants Est. completion 2024-08 1 site Stand-aloneOther conditions: Leukemia Lymphocytic Acute (ALL) in Relapse, Leukemia Lymphocytic Acute (All) Refractory, Lymphoma, B-Cell, CD19 PositiveView official trial listing → -
Active, not recruiting NCT NCT04049513
ENABLE-1 (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy)
Not yet reported Malaghan Institute of Medical Research 30 participants Est. completion 2029-03 1 site Stand-aloneOther conditions: Lymphomas Non-Hodgkin's B-Cell, Diffuse Large B-cell Lymphoma (DLBCL), Primary Mediastinal B-cell Lymphoma (PMBCL), Transformed Follicular Lymphoma (TFL), Follicular Lymphoma (FL), Mantle Cell Lymphoma (MCL)View official trial listing → -
Suspended NCT NCT04053062
LIGHT-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer
Not yet reported Bioray Laboratories 12 participants Est. completion 2024-10-15 1 site Stand-aloneOther conditions: Castrate-Resistant Prostate CancerView official trial listing → -
Terminated NCT NCT04067180
Randomized Clinical Study Assessing Haplo vs. URD in AML
Not yet reported Karolinska Institutet 18 participants Est. completion 2022-08-26 9 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT04067414
Exploratory Study of CD19-targeted Chimeric Antigen Receptor T Cells(BZ019) for Relapsed and Refractory B-cell Lymphoma
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 12 participants Est. completion 2021-06-04 1 site Stand-aloneOther conditions: Diffuse Large B Cell Lymphoma, High-grade B-cell Lymphoma, Transformed Lymphoma, Primary Mediastinal Large B Cell LymphomaView official trial listing → -
Completed NCT NCT04074746
Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomas
Not yet reported, Not yet reported M.D. Anderson Cancer Center 45 participants Est. completion 2025-09-23 1 site Stand-aloneOther conditions: Recurrent Anaplastic Large Cell Lymphoma, Recurrent B-Cell Non-Hodgkin Lymphoma, Recurrent Classic Hodgkin Lymphoma, Recurrent Mycosis Fungoides, Recurrent Peripheral T-Cell Lymphoma, Not Otherwise Specified, Refractory Anaplastic Large Cell Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, Refractory Classic Hodgkin Lymphoma, Refractory Mycosis Fungoides, Refractory Peripheral T-Cell Lymphoma, Not Otherwise SpecifiedView official trial listing → -
Terminated NCT NCT04083170
Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers
Not yet reported Fred Hutchinson Cancer Center 1 participants Est. completion 2022-11-30 5 sites Stand-aloneOther conditions: Acute Erythroid Leukemia, Acute Lymphoblastic Leukemia, Acute Megakaryoblastic Leukemia, Acute Myeloid Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid Cell Neoplasm, HIV Infection, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts, Non-Hodgkin Lymphoma, Refractory AnemiaView official trial listing → -
Completed NCT NCT04088864
CD22-CAR T Cells in Children and Young Adults With B Cell Malignancies
Not yet reported Kara Lynn Davis 10 participants Est. completion 2022-01-13 1 site Stand-aloneOther conditions: B Cell Lymphoma, Acute Lymphoblastic Leukemia, Pediatric, LymphomaView official trial listing → -
Completed NCT NCT04088890
Autologous CD22 CAR T Cells in Adults w/ Recurrent or Refractory B Cell Malignancies
Not yet reported Matthew Frank 52 participants Est. completion 2025-03-07 1 site Stand-aloneOther conditions: B-ALL, B-cell Non Hodgkin Lymphoma, DLBCL, Follicular Lymphoma Grade 3BView official trial listing → -
Completed NCT NCT04093596
Safety and Efficacy of ALLO-715 BCMA Allogenic CAR T Cells in in Adults With Relapsed or Refractory Multiple Myeloma (UNIVERSAL)
Not yet reported Allogene Therapeutics 73 participants Est. completion 2025-01-27 11 sites Stand-aloneOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Terminated NCT NCT04097301
Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma
Not yet reported, Not yet reported AGC Biologics S.p.A. 8 participants Est. completion 2021-06-18 3 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT04098393
Giving Chemotherapy for a Shortened Amount of Time Before a Stem Cell Transplantation
Not yet reported Memorial Sloan Kettering Cancer Center 39 participants Est. completion 2026-09 1 site Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Withdrawn NCT NCT04102436
Non-Viral TCR Gene Therapy
Not yet reported National Cancer Institute (NCI) Est. completion 2024-03-08 1 site Stand-aloneOther conditions: Endocrine/Neuroendocrine, Non-Small Cell Lung Cancer, Breast Cancer, Gastrointestinal/Genitourinary Cancers, Ovarian CancerView official trial listing → -
Completed NCT NCT04103879
US Study of UM171-Expanded CB in Patients With High Risk Leukemia/Myelodysplasia
Not yet reported ExCellThera inc. 30 participants Est. completion 2026-02-28 3 sites Stand-aloneOther conditions: High Risk Hematological Malignancy, Cord Blood TransplantView official trial listing → -
Terminated NCT NCT04109482
Trial to Evaluate the Safety and Efficacy of MB-102 in Patients With BPDCN.
Not yet reported, Not yet reported Mustang Bio 3 participants Est. completion 2023-05-17 4 sites Stand-aloneOther conditions: Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)View official trial listing → -
Status unknown NCT NCT04112589
A Clinical Trial to Assess the Efficacy and Safety of the Combination of a Drug Call Quizartinib With Chemotherapy (FLAG-IDA) in Patients With Acute Myeloid Leukemia That Has Not Responded to the First Treatment or That Has Returned After the First Treatment
Not yet reported, Not yet reported PETHEMA Foundation 63 participants Est. completion 2023-12 20 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT04121507
ASTRAL- a Clinical Study to Assess the Efficacy and Toxicity of High-dose Chemotherapy
Not yet reported GWT-TUD GmbH 60 participants Est. completion 2023-02-02 13 sitesOther conditions: Aggressive Non-hodgkin Lymphoma (aNHL), Lymphoma, B-Cell, Lymphoma, T-CellView official trial listing → -
No Longer Available NCT NCT04135092
Single Patient Protocol: A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab
National Institutes of Health Clinical Center (CC)View official trial listing → -
Completed NCT NCT04151706
CD34 Selected Allogeneic HCT w/ Myeloablative Conditioning Plus CD8+ Memory TCell Infusion in MDS, AL and CML
Not yet reported Robert Lowsky 7 participants Est. completion 2023-09-08 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, Acute Leukemia, Chronic Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04160195
T Cells Expressing Fully-human Anti-CD19 and Anti-CD20 Chimeric Antigen Receptors for Treating B-cell Malignancies and Hodgkin Lymphoma
Not yet reported National Cancer Institute (NCI) 2 participants Est. completion 2021-06-11 1 siteOther conditions: Lymphoma, B-Cell, Lymphoma, Non-hodgkins, Chronic Lymphocytic Leukemia, B-Cell Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT04161118
TisaGenlecleucel in Elderly Patients With First-Relapsed or Primary Refractory Aggressive B-cell Non-Hodgkin Lymphoma
Not yet reported University of Cologne 3 participants Est. completion 2023-02-24 2 sites Stand-aloneOther conditions: Non Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT04162119
Safety and Efficiency Study of BCMA-PD1-CART Cells in Relapsed/Refractory Multiple Myeloma
Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2022-10-10 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Approved For Marketing NCT NCT04162756
Study of Brexucabtagene Autoleucel (KTE-X19) for the Treatment of Individuals With Relapsed/Refractory B-Cell Malignancies
Kite, A Gilead Company 9 sitesOther conditions: Relapse/Refractory Mantle Cell LymphomaView official trial listing → -
Status unknown NCT NCT04163302
Safety and Efficiency Study of CD19-PD1-CART Cell in Relapsed/Refractory B Cell Lymphoma
Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2022-07-01 1 site Stand-aloneOther conditions: Lymphoma, B-CellView official trial listing → -
Completed NCT NCT04165967
Adoptive Tumor-infiltrating Lymphocyte Transfer With Nivolumab for Melanoma
Not yet reported University Hospital, Basel, Switzerland 9 participants Est. completion 2023-03-30 1 site Stand-aloneOther conditions: Advanced MelanomaView official trial listing → -
Active, not recruiting NCT NCT04167683
Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant
Copenhagen University Hospital, Rigshospitalet 144 participants Est. completion 2026-11-01 1 siteOther conditions: Hematologic Diseases, Chronic Myeloid Leukemia, Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Myelodysplastic Syndromes, Non Hodgkin Lymphoma, Stem Cell Transplant Complications, Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT04171843
A Dose-escalation Study to Evaluate the Safety and Clinical Activity of PBCAR269A, With or Without Nirogacestat, in Study Participants With Relapsed/Refractory Multiple Myeloma
Not yet reported Precision BioSciences, Inc. 48 participants Est. completion 2022-10-19 5 sites Stand-aloneOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04173988
Study of alloCART-19 Cell Therapy in Pediatric Patients With Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia
Not yet reported Children's Hospital of Fudan University 6 participants Est. completion 2025-07-20 1 site Stand-aloneOther conditions: ALL, Childhood B-CellView official trial listing → -
Active, not recruiting NCT NCT04181827
A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma
Not yet reported Janssen Research & Development, LLC 419 participants Est. completion 2027-03-31 88 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT04191187
Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 34 participants Est. completion 2024-02-14 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Biphenotypic Acute Leukemia, Undifferentiated Leukemia, Prolymphocytic Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Myeloproliferative Neoplasm, Relapsed Large Cell Lymphoma, Mantle Cell Lymphoma, Hodgkin Lymphoma, Burkitt Lymphoma, Relapsed T-Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, Relapsed Small Lymphocytic Lymphoma, Relapsed Marginal B-cell Lymphoma, Relapsed Follicular Lymphoma, Lymphoplasmacytic LymphomaView official trial listing → -
Status unknown NCT NCT04191941
Treatment of Hematological Malignancy With Novel CAR-T Cells.
Not yet reported Timmune Biotech Inc. 9 participants Est. completion 2021-12-31 1 site Stand-aloneOther conditions: B-cell Non Hodgkin Lymphoma, B-cell Acute Lymphoblastic Leukemia, Multiple MyelomaView official trial listing → -
Completed NCT NCT04196491
A Study to Evaluate the Safety of bb2121 in Subjects With High Risk, Newly Diagnosed Multiple Myeloma (NDMM)
Not yet reported Celgene 13 participants Est. completion 2023-06-07 22 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04204161
A Clinical Study of CAR-T Cells Treatment for Children With CD19+/CD22+ R/R ALL and Lymphoma
Not yet reported Shenzhen BinDeBio Ltd. 30 participants Est. completion 2024-10-08 1 site Stand-aloneOther conditions: Relapsed B-cell Acute Lymphoblastic Leukemia, Childhood, Refractory B-cell Acute Lymphoblastic Leukemia, Childhood, Relapsed/Refractory B-cell Lymphoma, ChildhoodView official trial listing → -
Terminated NCT NCT04205240
Reduce Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed Multiple Myeloma
Not yet reported Srinivas Devarakonda 1 participants Est. completion 2021-11-22 1 site Stand-aloneOther conditions: Recurrent Plasma Cell MyelomaView official trial listing → -
Terminated NCT NCT04205838
Anakinra in Preventing Severe Chimeric Antigen Receptor T-Cell Related Encephalopathy Syndrome in Patients With Recurrent or Refractory Large B-cell Lymphoma
Not yet reported Jonsson Comprehensive Cancer Center 23 participants Est. completion 2026-02-19 2 sites Stand-aloneOther conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, High Grade B-Cell Lymphoma, Progressive Disease, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent High Grade B-Cell Lymphoma, Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma, Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory High Grade B-Cell Lymphoma, Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma, Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell LymphomaView official trial listing → -
Status unknown NCT NCT04206943
Study of CD19 Specific Chimeric Antigen Receptor Positive T Cells (CAR-T) in ALL and NHL
Not yet reported, Not yet reported Acibadem University 24 participants Est. completion 2021-01-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Non Hodgkin LymphomaView official trial listing → -
Completed NCT NCT04213469
PD1-CD19-CART in Patients With r/r B-cell Lymphoma
Not yet reported Bioray Laboratories 20 participants Est. completion 2023-11-10 1 site Stand-aloneOther conditions: B-cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT04214886
CD19 Chimeric Antigen Receptor (CAR) T Cells for Adults With Recurrent or Refractory B Cell Malignancies
Not yet reported Loyola University 24 participants Est. completion 2034-12-31 1 site Stand-aloneOther conditions: B-Cell Acute Lymphoblastic Leukemia, Adult, B-cell Lymphoma Refractory, B-cell Lymphoma RecurrentView official trial listing → -
Active, not recruiting NCT NCT04217278
A Trial of Treatments to Assess the Effects on Outcome of Adults With AML and MDS Undergoing Allogeneic SCT
Not yet reported, Not yet reported University of Birmingham 333 participants Est. completion 2026-05 14 sites Stand-aloneOther conditions: Acute Myeloid Leukaemia, High-risk Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT04220684
Trial Testing Safety of IL-21 NK Cells for Induction of R/R AML
Not yet reported Sumithira Vasu 19 participants Est. completion 2024-10-22 2 sites Stand-aloneOther conditions: Allogeneic Stem Cell Transplant Recipient, Blasts 10 Percent or More of Bone Marrow Nucleated Cells, Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT04221971
NK Cell Infusion for Patients With Acute Myeloid Leukemia
Not yet reported Peking University People's Hospital 10 participants Est. completion 2022-04 1 siteOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04230265
Phase 1 Study of UniCAR02-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies
Not yet reported AvenCell Europe GmbH 32 participants Est. completion 2025-04-11 10 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Completed NCT NCT04230473
A Clinical Trial of CNCT19 Cells in the Treatment of CD19 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported Juventas Cell Therapy Ltd. 10 participants Est. completion 2022-11-01 2 sites Stand-aloneOther conditions: Relapsed or Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT04231747
A Study of CC-97540, CD19-targeted NEX-T Chimeric Antigen Receptor (CAR) T Cells, in Subjects With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported Juno Therapeutics, a Subsidiary of Celgene 24 participants Est. completion 2024-02-01 14 sites Stand-aloneOther conditions: Lymphoma Non-Hodgkin, Agressive Lymphoma, Diffuse-large B-cell Lymphoma (DLBCL)View official trial listing → -
Completed NCT NCT04232826
A Clinical Trial of CNCT19 Cells in the Treatment of CD19 Positive Relapsed or Refractory Diffuse Non-Hodgkin Lymphoma
Not yet reported Juventas Cell Therapy Ltd. 9 participants Est. completion 2022-11-01 2 sites Stand-aloneOther conditions: Diffuse Non-Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT04237428
CD19-CART in the Treatment of R/R CD19 Positive Non-Hodgkin's Lymphoma
Not yet reported PersonGen BioTherapeutics (Suzhou) Co., Ltd. 20 participants Est. completion 2021-05-31 1 site Stand-aloneOther conditions: Non Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT04240002
A Study of Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)
Not yet reported, Not yet reported Astellas Pharma Global Development, Inc. 9 participants Est. completion 2025-03-17 7 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Acute Myeloid Leukemia With FMS-like Tyrosine Kinase 3 (FLT3) Mutation / Internal Tandem Duplication (ITD)View official trial listing → -
Terminated NCT NCT04245722
FT596 as a Monotherapy and in Combination With Anti-CD20 Monoclonal Antibodies
Not yet reported Fate Therapeutics 98 participants Est. completion 2023-09-27 9 sites Stand-aloneOther conditions: Lymphoma, B-Cell, Chronic Lymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04245839
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)
Not yet reported Celgene 276 participants Est. completion 2031-09-30 49 sites Stand-aloneOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Terminated NCT NCT04250051
Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported Northwestern University 2 participants Est. completion 2022-12-20 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Recurrent Myeloproliferative Neoplasm, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic Syndrome, Newly Diagnosed Acute Myeloid Leukemia (AML), IDH1 Mutation Myeloid Neoplasms, Acute Myeloid Leukemia (AML)View official trial listing → -
Status unknown NCT NCT04250324
Study of Safety and Efficacy of BZ019 in (R/R) Large B-cell Lymphoma
Not yet reported Shanghai Cell Therapy Group Co.,Ltd 21 participants Est. completion 2022-12 2 sites Stand-aloneOther conditions: Large B-cell LymphomaView official trial listing → -
Completed NCT NCT04260932
CD19/CD20 Dual-CAR-T in B-cell Lymphoma Patients
Not yet reported Hebei Yanda Ludaopei Hospital 12 participants Est. completion 2021-09-10 1 site Stand-aloneOther conditions: B-cell LymphomaView official trial listing → -
Completed NCT NCT04260945
CD19/CD20 Dual-CAR-T in B-cell Leukemia Patients
Not yet reported Hebei Yanda Ludaopei Hospital 12 participants Est. completion 2022-02-10 1 site Stand-aloneOther conditions: B-cell LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04262843
Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia
Not yet reported City of Hope Medical Center 33 participants Est. completion 2027-05-11 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, Myelodysplastic SyndromeView official trial listing → -
Status unknown NCT NCT04264039
Anti-CD19 U-CAR-T Cell Therapy for B Cell Hematologic Malignancies
Not yet reported Xinqiao Hospital of Chongqing 30 participants Est. completion 2022-04-01 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic Leukemia, B-cell LymphomaView official trial listing → -
Status unknown NCT NCT04264078
Anti-CD7 U-CAR-T Cell Therapy for T/NK Cell Hematologic Malignancies
Not yet reported Xinqiao Hospital of Chongqing 30 participants Est. completion 2023-06-01 1 site Stand-aloneOther conditions: T-cell Leukemia, T-cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT04268706
Phase 2 Study Evaluating Autologous CD30.CAR-T Cells in Patients With Relapsed/Refractory Hodgkin Lymphoma (CHARIOT)
Not yet reported Tessa Therapeutics 97 participants Est. completion 2037-03 5 sites Stand-aloneOther conditions: Hodgkin Lymphoma, Adult, Hodgkin Disease Recurrent, Hodgkin Disease Refractory, Hodgkin Disease, PediatricView official trial listing → -
Completed NCT NCT04269811
Flu-Bu-Mel Conditioning Regimen for Myeloid Disease
Not yet reported Shanghai Jiao Tong University School of Medicine 49 participants Est. completion 2023-06-30 2 sites Stand-aloneOther conditions: Relapse Rate After Allo-HSCTView official trial listing → -
Withdrawn NCT NCT04282174
CD34+ Enriched Transplants From HLA-Compatible Patients With Hematologic Malignancies
Not yet reported Baptist Health South Florida Est. completion 2030-03-01 1 site Stand-aloneOther conditions: Hematologic Diseases, Hematologic Malignancy, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Chronic Myelogenous Leukemia, Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT04284228
Antigen-specific T Cell Therapy for AML or MDS Patients With Relapsed Disease After Allo-HCT
Not yet reported, Not yet reported NexImmune Inc. 22 participants Est. completion 2025-03 5 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS)View official trial listing → -
Completed NCT NCT04285567
A Study to Compare the Efficacy and Safety of a Combined Regimen of Venetoclax and Obinutuzumab Versus Fludarabine, Cyclophosphamide, and Rituximab (FCR)/ Bendamustine And Rituximab (BR) in FIT Patients With Previously Untreated Chronic Lymphocytic Leukemia (CLL) Without DEL (17P) or TP53 Mutation
Not yet reported Hoffmann-La Roche 166 participants Est. completion 2025-03-19 40 sitesOther conditions: Chronic Lymphocytic Leukemia (CLL)View official trial listing → -
Status unknown NCT NCT04303247
CD19 and CD22 Dual-targeted CAR-T Cells for Relapsed or Refractory B-NHL
Not yet reported Xinqiao Hospital of Chongqing 30 participants Est. completion 2023-05-01 1 site Stand-aloneOther conditions: B-cell Lymphoma Refractory, B-cell Lymphoma RecurrentView official trial listing → -
Status unknown NCT NCT04303520
Anti-CD19/CD22 Bispecific CAR-T Cell Therapy for CD19-positive ALL
Not yet reported The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine 20 participants Est. completion 2021-02 1 site Stand-aloneOther conditions: CD19-positive ALLView official trial listing → -
Terminated NCT NCT04310592
Natural Killer Cell (CYNK-001) Infusions in Adults with AML
Not yet reported Celularity Incorporated 27 participants Est. completion 2023-04-28 10 sites Stand-aloneOther conditions: Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute, Neoplasms by Histologic Type, Neoplasms, Immunosuppressive Agents, Immunologic Factors, Physiological Effects of Drugs, Alkylating Agents, Antimetabolites, Antineoplastic, Antiviral Agents, Analgesics, Non-narcotic, Anti-infective Agents, Analgesics, Peripheral Nervous System Agents, Hematologic Diseases, Hematologic Neoplasms, Leukemia in Remission, Relapsed Adult AML, Refractory AMLView official trial listing → -
Terminated NCT NCT04314843
Study of Lenzilumab and Axicabtagene Ciloleucel in Participants With Relapsed or Refractory Large B-Cell Lymphoma
Not yet reported Kite, A Gilead Company 6 participants Est. completion 2022-07-27 10 sites Stand-aloneOther conditions: Relapsed/Refractory Large B-cell LymphomaView official trial listing → -
Completed NCT NCT04319757
ACE1702 in Subjects With Advanced or Metastatic HER2-expressing Solid Tumors
Not yet reported Acepodia Biotech, Inc. 12 participants Est. completion 2024-07-15 3 sites Stand-aloneOther conditions: Locally Advanced Solid Tumor, Metastatic Cancer, Solid Tumor, HER2-positive Gastric Cancer, HER2-positive Metastatic Breast CancerView official trial listing → -
Completed NCT NCT04323657
TC-110 T Cells in Adults With Relapsed or Refractory Non-Hodgkin Lymphoma or Acute Lymphoblastic Leukemia
Not yet reported, Not yet reported TCR2 Therapeutics 6 participants Est. completion 2023-02-24 3 sites Stand-aloneOther conditions: Non Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, Diffuse Large B Cell Lymphoma, Primary Mediastinal Large B Cell Lymphoma, Mantle Cell Lymphoma, Follicular LymphomaView official trial listing → -
Completed NCT NCT04325841
Phase II Study of Anti-CD19 CAR-T Cells Treating Leukemia Children
Not yet reported Beijing Boren Hospital 2 participants Est. completion 2024-04-03 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Pediatric, Acute Lymphoblastic Leukemia, in Relapse, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT04336501
Efficacy and Safety Evaluation of IM19 CAR-T Cell Therapy for MRD+ After Transplantation
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 20 participants Est. completion 2021-12-01 1 site Stand-aloneOther conditions: LeukemiaView official trial listing → -
Completed NCT NCT04339101
Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation
Not yet reported City of Hope Medical Center 59 participants Est. completion 2025-10-09 1 site Stand-aloneOther conditions: Acute Leukemia, Hematologic and Lymphocytic Disorder, Myelodysplastic Syndrome, Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Completed NCT NCT04340167
Study of Anti-CD22 CAR-T Cells Treating Leukemia Children
Not yet reported Beijing Boren Hospital 14 participants Est. completion 2024-04-03 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Lymphoblastic Leukemia, in Relapse, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT04347616
Natural Killer-cell Therapy for Acute Myeloid Leukemia
Not yet reported, Not yet reported Radboud University Medical Center 9 participants Est. completion 2026-01-30 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, Relapsed, AdultView official trial listing → -
Withdrawn NCT NCT04354025
Cytokine-induced Memory-like NK Cells in Combination With Chemotherapy in Pediatric Patents With Refractory or Relapsed AML
Not yet reported Washington University School of Medicine Est. completion 2028-07-31 Stand-aloneOther conditions: Refractory Acute Myeloid Leukemia, Relapsed Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04384692
Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis
Not yet reported Fred Hutchinson Cancer Center 53 participants Est. completion 2030-04-23 1 site Stand-aloneOther conditions: Primary Myelofibrosis, Secondary MyelofibrosisView official trial listing → -
Status unknown NCT NCT04385641
Study on the Safety and Effectiveness of UCB-NK Cell Infusion in the Treatment of Advanced Gastric Cancer and Gastroesophageal Cancer
Not yet reported Shandong Golden Brick Biotechnology Co., Ltd. 18 participants Est. completion 2022-10-08 1 site Stand-aloneOther conditions: Advanced Gastric Cancer, Gastroesophageal CancerView official trial listing → -
Withdrawn NCT NCT04389229
OVSTAR TIL Trial (OVarian Cancer Co-STimulatory Antigen Receptor TIL Trial)
Not yet reported, Not yet reported Immetacyte Ltd Est. completion 2025-07-31 2 sites Stand-aloneOther conditions: Ovarian Cancer MetastaticView official trial listing → -
Withdrawn NCT NCT04395092
Haplo-identical Natural Killer (NK) Cells to Prevent Post-Transplant Relapse in AML and MDS (NK-REALM)
Not yet reported Kiadis Pharma Est. completion 2023-11 2 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)View official trial listing → -
Active, not recruiting NCT NCT04395222
Tocilizumab for the Prevention of Graft Failure and GVHD in Haplo-Cord Transplantation
Not yet reported Weill Medical College of Cornell University 21 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Hematologic Malignancy, Bone Marrow TransplantView official trial listing → -
Status unknown NCT NCT04400045
Low Dose Treosulfan Based Conditioning Regimen in HSCT for Nijmegen Breakage Syndrome
Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 10 participants Est. completion 2023-05 1 site Stand-aloneOther conditions: Nijmegen Breakage SyndromeView official trial listing → -
Active, not recruiting NCT NCT04404660
A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)
Not yet reported, Not yet reported Autolus Limited 153 participants Est. completion 2029-06-30 34 sites Stand-aloneOther conditions: Relapsed or Refractory B Cell Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04416984
Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell Lymphoma, Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (ALPHA2)
Not yet reported, Not yet reported Allogene Therapeutics 160 participants Est. completion 2029-05 29 sites Stand-aloneOther conditions: Relapsed or Refractory Large B Cell Lymphoma, Relapsed or Refractory Chronic Lymphocytic Leukemia, Relapsed or Refractory Small Lymphocytic LymphomaView official trial listing → -
Terminated NCT NCT04425655
Fludarabine in Combination With Daunorubicin and Cytarabine Liposome in Newly-diagnosed Acute Myeloid Leukemia.
Not yet reported University of California, San Diego 2 participants Est. completion 2022-07-01 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Adult, AML, AML, AdultView official trial listing → -
Completed NCT NCT04426669
A Study of Metastatic Gastrointestinal Cancers Treated With Tumor Infiltrating Lymphocytes in Which the Gene Encoding the Intracellular Immune Checkpoint CISH Is Inhibited Using CRISPR Genetic Engineering
Not yet reported, Not yet reported Intima Bioscience, Inc. 23 participants Est. completion 2026-01-22 1 site Stand-aloneOther conditions: Gastrointestinal Epithelial Cancer, Gastrointestinal Neoplasms, Cancer of Gastrointestinal Tract, Cancer, Gastrointestinal, Gastrointestinal Cancer, Colo-rectal Cancer, Pancreatic Cancer, Gall Bladder Cancer, Colon Cancer, Esophageal Cancer, Stomach CancerView official trial listing → -
Completed NCT NCT04429191
JSP191 Antibody Conditioning Regimen in MDS/AML Subjects Undergoing Allogenic Hematopoietic Stem Cell Transplantation
Not yet reported Jasper Therapeutics, Inc. 32 participants Est. completion 2023-06-13 6 sitesOther conditions: MYELODYSPLASTIC SYNDROME; MDS, ACUTE MYELOID LEUKEMIA; AMLView official trial listing → -
Completed NCT NCT04432506
Anakinra for the Reduction of CAR-T Toxicity in Patients With Relapsed or Refractory Large B-cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 22 participants Est. completion 2024-05-28 1 site Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell Neoplasm, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent High Grade B-Cell Lymphoma, Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory High Grade B-Cell Lymphoma, Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma, Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell LymphomaView official trial listing → -
Status unknown NCT NCT04447547
Clinical Trial of SL1904B CAR-T Cells for Relapsed or Refractory Non-Hodgkin Lymphoma
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 20 participants Est. completion 2022-12-30 2 sites Stand-aloneOther conditions: Non-hodgkin's LymphomaView official trial listing → -
Status unknown NCT NCT04447573
Immunotherapy With BCMA CAR-T Cells in Treating Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 20 participants Est. completion 2022-12-30 2 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT04473911
Haplo Peripheral Blood Sct In GVHD Prevention
Not yet reported Zachariah Michael DeFilipp 25 participants Est. completion 2024-08-19 1 site Stand-aloneOther conditions: GVHD, AML, ALL, MDS, MPN, CMML, Hodgkin Lymphoma, Non Hodgkin Lymphoma, Blood Stem Cell Transplant Failure, Graft Vs Host Disease, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Myelodysplastic Syndromes, Myeloproliferative Disorder, Chronic Myelomonocytic Leukemia, Chemosensitive Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT04476251
E7 TCR T Cell Induction Immunotherapy for Stage IIB-IVA Cervical Cancer
Not yet reported National Cancer Institute (NCI) 1 participants Est. completion 2021-09-15 1 siteOther conditions: Uterine Cervical NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT04499573
Bispecific CD19/CD22 CAR-T for Treatment of Children and Young Adults With r/r B-ALL
Not yet reported, Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 50 participants Est. completion 2027-03-13 1 site Stand-aloneOther conditions: B-ALLView official trial listing → -
Terminated NCT NCT04508842
CD19/CD22-Dual-STAR-T for Patients With B Cell Acute Leukemia(B-ALL)
Not yet reported Hebei Yanda Ludaopei Hospital 2 participants Est. completion 2022-05-01 1 site Stand-aloneOther conditions: Refractory and Relapsed B Cell Acute LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04511871
A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors
Not yet reported Shanghai PerHum Therapeutics Co., Ltd. 12 participants Est. completion 2025-03-29 1 site Stand-aloneOther conditions: Solid Tumor, Gastric Cancer, Breast Cancer, Ovarian Cancer, SarcomaView official trial listing → -
Status unknown NCT NCT04516551
Anti-CD19 Allo-CAR-T Cells for Relapsed B Cell Malignancies After HSCT
Not yet reported Xinqiao Hospital of Chongqing 18 participants Est. completion 2022-12-01 1 site Stand-aloneOther conditions: Relapsed Adult ALL, B Cell LeukemiaView official trial listing → -
Withdrawn NCT NCT04521946
Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer
Not yet reported M.D. Anderson Cancer Center Est. completion 2022-12-20 Stand-aloneOther conditions: Anaplastic Ependymoma, Atypical Teratoid/Rhabdoid Tumor, Central Nervous System Germ Cell Tumor, Choroid Plexus Carcinoma, Intracranial Myeloid Sarcoma, Malignant Brain Neoplasm, Malignant Glioma, Medulloblastoma, Primitive Neuroectodermal Tumor, Recurrent Anaplastic Ependymoma, Recurrent Atypical Teratoid/Rhabdoid Tumor, Recurrent Malignant Brain Neoplasm, Recurrent Malignant Glioma, Recurrent Medulloblastoma, Recurrent Primitive Neuroectodermal TumorView official trial listing → -
Terminated NCT NCT04526509
Master Protocol to Assess Safety and Dose of First Time in Human Next Generation Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Advanced Solid Tumors
Not yet reported Adaptimmune 12 participants Est. completion 2023-06-08 17 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Terminated NCT NCT04526795
Fludarabine, Cytarabine, and Pegcrisantaspase for the Treament of Relapsed or Refractory Leukemia
Not yet reported M.D. Anderson Cancer Center 19 participants Est. completion 2024-11-15 1 site Stand-aloneOther conditions: Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent Acute Biphenotypic Leukemia, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia, Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Recurrent T-Cell Prolymphocytic Leukemia, Refractory Acute Biphenotypic Leukemia, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Refractory T-Cell Prolymphocytic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04526834
Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma
Not yet reported Tessa Therapeutics 21 participants Est. completion 2036-03 4 sites Stand-aloneOther conditions: Anaplastic Large Cell Lymphoma, Peripheral T Cell Lymphoma, Extranodal NK/T-cell Lymphoma, Diffuse Large B Cell Lymphoma, Primary Mediastinal Large B-Cell Lymphoma (PMBCL)View official trial listing → -
Terminated NCT NCT04530487
Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults
Not yet reported M.D. Anderson Cancer Center 1 participants Est. completion 2024-08-26 1 site Stand-aloneObstructive sleep apnea Other conditions: Desmoplastic Small Round Cell Tumor, Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, Recurrent Desmoplastic Small Round Cell Tumor, Recurrent Malignant Peripheral Nerve Sheath Tumor, Recurrent Malignant Solid Neoplasm, Recurrent Neuroblastoma, Refractory Desmoplastic Small Round Cell Tumor, Refractory Malignant Peripheral Nerve Sheath Tumor, Refractory Malignant Solid Neoplasm, Refractory NeuroblastomaView official trial listing → -
Withdrawn NCT NCT04536922
Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated or Viral Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab
Not yet reported National Cancer Institute (NCI) Est. completion 2021-01-27 1 site Stand-aloneOther conditions: Metastatic HPV-16 Positive Squamous Cell Anal CancerView official trial listing → -
Status unknown NCT NCT04537442
Clinical Study to Evaluate the Safety and Efficacy of IM21 CAR-T Cells in the Treatment of Elderly Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 10 participants Est. completion 2023-03-02 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Suspended NCT NCT04539366
Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, GD2-CAR PERSIST Trial
Not yet reported National Cancer Institute (NCI) 73 participants Est. completion 2040-12-31 6 sites Stand-aloneObstructive sleep apnea Other conditions: Recurrent Childhood Neuroblastoma, Recurrent Neuroblastoma, Refractory Childhood Neuroblastoma, Refractory NeuroblastomaView official trial listing → -
Active, not recruiting NCT NCT04540380
Renal Allograft Tolerance Through Mixed Chimerism - SMC/MGH
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2029-06 1 siteOther conditions: Renal FailureView official trial listing → -
Status unknown NCT NCT04546893
Safety and Efficacy Study of SL1904B CAR-T Cells for Relapsed or Refractory B-Cell Acute Lymphocyte Leukemia
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 20 participants Est. completion 2022-12-01 2 sites Stand-aloneOther conditions: B-ALLView official trial listing → -
Status unknown NCT NCT04546906
Safety and Efficacy Study of CD22 CAR-T Cells for Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 20 participants Est. completion 2022-12-01 2 sites Stand-aloneOther conditions: B-ALLView official trial listing → -
Active, not recruiting NCT NCT04547049
A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies
Not yet reported First Affiliated Hospital of Zhejiang University 232 participants Est. completion 2026-04-01 8 sitesOther conditions: Leukemia, MDSView official trial listing → -
Terminated NCT NCT04551885
FT516 in Combination With Monoclonal Antibodies in Advanced Solid Tumors
Not yet reported Fate Therapeutics 12 participants Est. completion 2023-08-11 3 sites Stand-aloneOther conditions: Solid Tumor, AdultView official trial listing → -
Terminated NCT NCT04562298
A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of LCAR-M23, a CAR-T Cell Therapy Targeting MSLN in Patients With Relapsed and Refractory Epithelial Ovarian Cancer
Not yet reported Shanghai East Hospital 15 participants Est. completion 2022-06-07 1 site Stand-aloneOther conditions: Epithelial Ovarian CancerView official trial listing → -
Completed NCT NCT04572308
Cell Therapy for CD7 Positive T-cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma Using CD7-Specific CAR-T Cells
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 20 participants Est. completion 2021-05-30 1 site Stand-aloneOther conditions: T-cell Acute Lymphoblastic Leukemia/LymphomaView official trial listing → -
Withdrawn NCT NCT04579523
²¹¹At-OKT10-B10 and Fludarabine Alone or in Combination With Cyclophosphamide and Low-Dose TBI Before Donor Stem Cell Transplant for the Treatment of Newly Diagnosed, Recurrent, or Refractory High-Risk Multiple Myeloma
Not yet reported Fred Hutchinson Cancer Center Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Multiple Myeloma, Recurrent Multiple Myeloma, Refractory Multiple MyelomaView official trial listing → -
Terminated NCT NCT04596033
TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapy
Not yet reported Genocea Biosciences, Inc. 49 participants Est. completion 2022-06-27 8 sites Stand-aloneOther conditions: Melanoma, Non-small Cell Lung Cancer, Squamous Cell Carcinoma of Head and Neck, Urothelial Carcinoma, Renal Cell Carcinoma, Small-cell Lung Cancer, Cutaneous Squamous Cell Carcinoma, Anal Squamous Cell Carcinoma, Merkel Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT04608487
Axi-cel in CNS Lymphoma
Not yet reported Dana-Farber Cancer Institute 18 participants Est. completion 2038-06-14 2 sites Stand-aloneOther conditions: Lymphoma, Lymphoma CnsView official trial listing → -
Status unknown NCT NCT04610125
Clinical Trial of CAR-T in the Treatment of Relapsed and Refractory Hematopoietic and Lymphoid Tissue Tumors in Children
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 30 participants Est. completion 2025-06-22 1 site Stand-aloneOther conditions: Leukemia, LymphomaView official trial listing → -
Terminated NCT NCT04611126
T-cell Therapy in Combination With Nivolumab, Relatlimab and Ipilimumab for Patients With Metastatic Ovarian Cancer
Not yet reported, Not yet reported Inge Marie Svane 6 participants Est. completion 2024-03-03 1 siteOther conditions: Metastatic Ovarian Cancer, Metastatic Fallopian Tube Cancer, Peritoneal CancerView official trial listing → -
Active, not recruiting NCT NCT04613557
Safety, Activity and Cell Kinetics of CYAD-211 in Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported Celyad Oncology SA 18 participants Est. completion 2037-02 5 sites Stand-aloneOther conditions: Relapse/Refractory Multiple MyelomaView official trial listing → -
Terminated NCT NCT04614636
FT538 in Subjects With Advanced Hematologic Malignancies
Not yet reported Fate Therapeutics 42 participants Est. completion 2023-08-08 8 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, AML, Adult, Multiple Myeloma, MyelomaView official trial listing → -
Active, not recruiting NCT NCT04623944
NKX101, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS
Not yet reported Nkarta, Inc. 61 participants Est. completion 2039-07 8 sites Stand-aloneOther conditions: Relapsed/Refractory AML, AML, Adult, MDS, Refractory Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT04626726
Adult B-ALL Treated by CART Cell Bridging Allogeneic Hematopoietic Stem Cell Transplantation
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 50 participants Est. completion 2023-05-30 1 site Stand-aloneOther conditions: Adult B Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT04626739
CAR-T Cells in Treating Patients With Relapsed or Refractory NHL
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 100 participants Est. completion 2023-03-30 1 site Stand-aloneOther conditions: Refractory Indolent Adult Non-Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT04626752
CAR-T Cells in Treating Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 50 participants Est. completion 2023-03-30 1 site Stand-aloneOther conditions: Relapsed or Refractory Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04626765
CAR-T for Children With Relapsed and Refractory Acute Lymphoblastic Leukemia
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 50 participants Est. completion 2023-05-30 1 site Stand-aloneOther conditions: Childhood Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04629729
FT819 in Subjects With B-cell Malignancies
Not yet reported Fate Therapeutics 54 participants Est. completion 2039-09-30 18 sites Stand-aloneOther conditions: Lymphoma, B-Cell, Chronic Lymphocytic Leukemia, Precursor B-Cell Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT04632316
A Trial to Evaluate the Safety and Efficacy of oNKord® in Subjects With Acute Myeloid Leukemia
Not yet reported, Not yet reported Glycostem Therapeutics BV 33 participants Est. completion 2023-04 10 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04633148
Dose-escalating Trial With UniCAR02-T Cells and PSMA Target Module (TMpPSMA) in Patients With Progressive Disease After Standard Systemic Therapy in Cancers With Positive PSMA Marker
Not yet reported AvenCell Europe GmbH 16 participants Est. completion 2024-03-28 4 sites Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Status unknown NCT NCT04637269
Anti-BCMA CAR-T Cell Therapy for the R/R Multiple Myeloma
Not yet reported Xinqiao Hospital of Chongqing 16 participants Est. completion 2023-11-01 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04637763
CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)
Not yet reported Caribou Biosciences, Inc. 72 participants Est. completion 2025-09 38 sites Stand-aloneOther conditions: Lymphoma, Non-Hodgkin, Relapsed Non Hodgkin Lymphoma, Refractory B-Cell Non-Hodgkin Lymphoma, Non Hodgkin Lymphoma, Lymphoma, B Cell Lymphoma, B Cell Non-Hodgkin's LymphomaView official trial listing → -
Status unknown NCT NCT04638270
Anti-CD19 FasT CAR-T Cell Therapy for B Cell NHL
Not yet reported Xinqiao Hospital of Chongqing 16 participants Est. completion 2023-11-01 1 site Stand-aloneOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Terminated NCT NCT04639245
Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 1 participants Est. completion 2022-08-16 1 site Stand-aloneOther conditions: Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Solid Neoplasm, Metastatic Triple-Negative Breast Carcinoma, Metastatic Urothelial Carcinoma, Stage IV Lung Cancer AJCC v8View official trial listing → -
Status unknown NCT NCT04639739
Anti-CD19 CAR NK Cell Therapy for R/R Non-Hodgkin Lymphoma.
Not yet reported Xinqiao Hospital of Chongqing 9 participants Est. completion 2023-12-01 1 site Stand-aloneOther conditions: NHLView official trial listing → -
Active, not recruiting NCT NCT04643574
NeoTIL in Advanced Solid Tumors
Not yet reported Centre Hospitalier Universitaire Vaudois 42 participants Est. completion 2027-11 1 site Stand-aloneOther conditions: Solid Tumor, AdultView official trial listing → -
Status unknown NCT NCT04653493
CD19 Targeted CAR T Cell Therapy in Patients With Relapsed/ Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)
Not yet reported Sabz Biomedicals 22 participants Est. completion 2024-08 2 sites Stand-aloneOther conditions: Relapsed B Cell Acute Lymphoblastic Leukemia (ALL), Refractory B Cell Acute Lymphoblastic Leukemia (ALL)View official trial listing → -
Status unknown NCT NCT04662099
T Cells Expressing a Bispecific CAR Targeting CS1 and BCMA in Relapsed/Refractory Multiple Myeloma
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 24 participants Est. completion 2023-12-30 1 site Stand-aloneOther conditions: CS1+ or BCMA+ Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04665063
A Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Hodgkin's Lymphoma
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 20 participants Est. completion 2025-10-21 1 site Stand-aloneOther conditions: Hodgkin's LymphomaView official trial listing → -
Status unknown NCT NCT04665076
Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Plasma Cell Tumors
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 60 participants Est. completion 2025-10-21 1 site Stand-aloneOther conditions: Plasma Cell TumorsView official trial listing → -
Status unknown NCT NCT04666168
A Multicenter Clinical Study on the Safety and Efficacy of CAR-T in the Treatment of Relapsed / Refractory Non Hodgkin's Lymphoma
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 200 participants Est. completion 2025-10-21 1 site Stand-aloneOther conditions: Non-hodgkin's LymphomaView official trial listing → -
Completed NCT NCT04669210
PTCy and Ruxolitinib vs PTCy, Tacrolimus and MMF in MUD and Haploidentical HSCT
Not yet reported St. Petersburg State Pavlov Medical University 128 participants Est. completion 2025-03-28 2 sites Stand-aloneOther conditions: Graft-versus-host-disease, Stem Cell Transplant Complications, Acute Myeloid Leukemia, Acute Lymphoid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04670068
Phase I Study of Autologous CAR T-Cells Targeting the B7-H3 Antigen in Recurrent Epithelial Ovarian
Not yet reported UNC Lineberger Comprehensive Cancer Center 4 participants Est. completion 2030-02 1 site Stand-aloneOther conditions: Epithelial Ovarian CancerView official trial listing → -
Completed NCT NCT04673617
AB-101 as Monotherapy and With Immunotherapy in Patients With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma
Not yet reported, Not yet reported Artiva Biotherapeutics, Inc. 45 participants Est. completion 2025-10-06 21 sites Stand-aloneOther conditions: Non Hodgkin LymphomaView official trial listing → -
Completed NCT NCT04674813
A Study of CC-95266 in Participants With Relapsed and/or Refractory Multiple Myeloma
Not yet reported Juno Therapeutics, a Subsidiary of Celgene 130 participants Est. completion 2025-12-22 10 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04677452
Dose Exploration Study OF JWCAR129, BCMA-Targeted CART for RRMM
Not yet reported The First Affiliated Hospital of Soochow University 24 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Safety and EfficacyView official trial listing → -
Terminated NCT NCT04678336
CD123 Redirected T Cells for AML in Pediatric Subjects
Not yet reported University of Pennsylvania 12 participants Est. completion 2025-05-09 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia, Pediatric, Acute Myeloid Leukemia, RefractoryView official trial listing → -
Active, not recruiting NCT NCT04696731
Safety and Efficacy of ALLO-316 in Subjects With Advanced or Metastatic Clear Cell Renal Cell Carcinoma
Not yet reported Allogene Therapeutics 120 participants Est. completion 2030-01 10 sites Stand-aloneOther conditions: Advanced/Metastatic Clear Cell Renal Cell CarcinomaView official trial listing → -
Suspended NCT NCT04697290
CD19/CD20 Dual-CAR-T in B-cell Non-Hodgkin's Lymphoma Patients.
Not yet reported Beijing Tsinghua Chang Gung Hospital 12 participants Est. completion 2023-06-10 1 site Stand-aloneOther conditions: B-cell Non-Hodgkin's LymphomaView official trial listing → -
Active, not recruiting NCT NCT04697940
Decitabine-primed Tandem CD19/CD20 CAR T Cells Treatment in r/r B-NHL
Not yet reported, Not yet reported Han weidong 33 participants Est. completion 2026-09-01 1 site Stand-aloneOther conditions: Relapsed and Refractory B-cell Non-Hodgkin's Lymphoma, Decitabine-primed Tandem CD19/CD20 CAR T CellsView official trial listing → -
Status unknown NCT NCT04706936
Novel BCMA-targeted CAR-T Cell Therapy for Multiple Myeloma
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 25 participants Est. completion 2024-04 1 site Stand-aloneOther conditions: Relapsed or Refractory Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04713956
G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for RAEB-1,REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 242 participants Est. completion 2024-07-31 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, Allogeneic Hematopoietic Stem Cell Transplantation, ConditioningView official trial listing → -
Completed NCT NCT04714372
FT538 in Combination With Daratumumab in AML Acute Myeloid Leukemia
Not yet reported Masonic Cancer Center, University of Minnesota 9 participants Est. completion 2024-10-15 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myeloid Leukemia, Monocytic LeukemiaView official trial listing → -
Status unknown NCT NCT04716114
A Study of SKLB1028 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory (R/R) AML With FLT3-Mutated
Not yet reported CSPC ZhongQi Pharmaceutical Technology Co., Ltd. 315 participants Est. completion 2025-12 1 siteOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Terminated NCT NCT04727151
TAC T-cells for the Treatment of HER2-positive Solid Tumors
Not yet reported, Not yet reported Triumvira Immunologics, Inc. 28 participants Est. completion 2024-03-25 11 sites Stand-aloneOther conditions: HER2 Positive Gastric Cancer, Metastatic HER2 Positive Gastroesophageal Junction CancerView official trial listing → -
Status unknown NCT NCT04728490
Haplo-identical Transplantation in Patients With Myelofibrosis - A Phase 2 Prospective Multicentric Prospective Study
Not yet reported Assistance Publique - Hôpitaux de Paris 28 participants Est. completion 2024-01-30 Stand-aloneOther conditions: MyelofibrosisView official trial listing → -
Active, not recruiting NCT NCT04732845
Human AntiCD19 Chimeric Antigen Receptor T Cells for Relapsed or Refractory Lymphoid Malignancies
Not yet reported Benjamin Tomlinson 18 participants Est. completion 2040-12-01 1 site Stand-aloneOther conditions: Non Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT04735471
A Phase 1 Study of ADI-001 in B Cell Malignancies
Not yet reported Adicet Therapeutics 34 participants Est. completion 2025-02-03 10 sites Stand-aloneOther conditions: Lymphoma, Follicular, Lymphoma, Mantle-Cell, Marginal Zone Lymphoma, Primary Mediastinal B-cell Lymphoma, Diffuse Large B Cell Lymphoma, Lymphoma, Non-HodgkinView official trial listing → -
Active, not recruiting NCT NCT04756648
Phase I Clinical Trial of CT0180 Cells in the Treatment of Hepatocellular Carcinoma
Not yet reported Zhejiang University 21 participants Est. completion 2026-06-01 1 site Stand-aloneOther conditions: Advanced Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT04766320
Study on TIL for the Treatment of r/r Gynecologic Tumors
Not yet reported Shanghai 10th People's Hospital 15 participants Est. completion 2025-01-31 1 site Stand-aloneOther conditions: Gynecologic CancerView official trial listing → -
Status unknown NCT NCT04766840
Donor-derived CAR-T Cells in the Treatment of AML Patients
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 9 participants Est. completion 2023-12-01 1 site Stand-aloneOther conditions: AMLView official trial listing → -
Status unknown NCT NCT04767308
Safety and Efficacy of CT125A Cells for Treatment of Relapsed/Refractory CD5+ Hematopoietic Malignancies
Not yet reported Huazhong University of Science and Technology 18 participants Est. completion 2023-12 Stand-aloneOther conditions: CD5+ Relapsed/Refractory Hematopoietic Malignancies, Chronic Lymphocytic Leukemia (CLL), Mantle Cell Lymphoma (MCL), Diffuse Large B-cell Lymphoma (DLBCL), Follicular Lymphoma (FL), Peripheral T-cell Lymphomas (PTCL)View official trial listing → -
Completed NCT NCT04768608
PD1 Integrated Anti-PSMA CART in Treating Patients With Castrate-Resistant Prostate Cancer
Not yet reported Zhejiang University 3 participants Est. completion 2023-05-30 1 site Stand-aloneOther conditions: Castrate-Resistant Prostate CancerView official trial listing → -
Withdrawn NCT NCT04776850
Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies
Not yet reported M.D. Anderson Cancer Center Est. completion 2022-12-05 Stand-aloneOther conditions: Beta Thalassemia Major, Sickle Beta 0 Thalassemia, Sickle Beta Plus Thalassemia, Sickle Beta Thalassemia, Sickle Cell Disease, Sickle Cell-SS DiseaseView official trial listing → -
Active, not recruiting NCT NCT04787263
CD19-CAR_Lenti T Cells in Pediatric Patients Affected by Relapsed/Refractory CD19+ ALL and DLBCL or PML
Not yet reported, Not yet reported Bambino Gesù Hospital and Research Institute 32 participants Est. completion 2038-03-03 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Diffuse Large B Cell Lymphoma, Primary Mediastinal LymphomaView official trial listing → -
Terminated NCT NCT04789408
Study of KITE-222 in Participants With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Kite, A Gilead Company 15 participants Est. completion 2024-05-18 9 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT04792593
Senl-h19 CAR-T Cell Injection in the Treatment of Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 15 participants Est. completion 2022-02-10 1 site Stand-aloneOther conditions: B-ALLView official trial listing → -
Status unknown NCT NCT04796441
Clinical Study of Universal CAR-γδT Cell Injection in the Treatment of Patients With Relapsed AML After Transplantation
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 20 participants Est. completion 2022-02-16 1 site Stand-aloneOther conditions: AMLView official trial listing → -
Status unknown NCT NCT04796675
Cord Blood Derived Anti-CD19 CAR-Engineered NK Cells for B Lymphoid Malignancies
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 27 participants Est. completion 2024-03-10 1 site Stand-aloneOther conditions: Acute Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, Non Hodgkin's LymphomaView official trial listing → -
Status unknown NCT NCT04796688
Universal Chimeric Antigen Receptor-modified AT19 Cells for CD19+ Relapsed/Refractory Hematological Malignancies
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 27 participants Est. completion 2024-03-10 2 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Chronic Lymphoblastic Leukemia, B-cell LymphomaView official trial listing → -
Terminated NCT NCT04803058
A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PERSPECTIVE)
Not yet reported ITB-Med LLC 7 participants Est. completion 2026-02-17 3 sitesOther conditions: Kidney TransplantationView official trial listing → -
Terminated NCT NCT04809766
Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma
Not yet reported Fred Hutchinson Cancer Center 9 participants Est. completion 2025-01-15 1 site Stand-aloneOther conditions: Metastatic Pancreatic Ductal Adenocarcinoma, Stage IV Pancreatic Cancer AJCC v8View official trial listing → -
Completed NCT NCT04812691
CD19-targeted CAR T Cells (JWCAR029) for Primary Refractory Diffuse Large B Cell Lymphoma
Not yet reported Shanghai Ming Ju Biotechnology Co., Ltd. 12 participants Est. completion 2023-04-25 2 sites Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Status unknown NCT NCT04823091
Anti-CD7 CAR-Engineered T Cells for T Lymphoid Malignancies Malignancies
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 24 participants Est. completion 2024-04-07 1 site Stand-aloneOther conditions: T-Cell Lymphocytic Leukemia, T-Cell Chronic Lymphocytic Leukemia, T Cell Non-Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT04825496
Clinical Study of ssCART-19 Cells in Patients With CD19 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia
Not yet reported Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd 18 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Relapsed or Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT04844086
RPM CD19-mbIL15-CAR-T Cells in Patient With Advanced Lymphoid Malignancies
Not yet reported Eden BioCell Ltd. 2 participants Est. completion 2022-05-12 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic Leukemia, Non-Hodgkin's Lymphoma, Relapsed, Non-Hodgkin's Lymphoma Refractory, Primary Mediastinal Large B Cell Lymphoma, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, Mantle Cell Lymphoma, High-grade B-cell LymphomaView official trial listing → -
Status unknown NCT NCT04844177
Total Lymphoid Irradiation Pre-HSCT in Severe Congenital Neutropenia
Not yet reported Federal Research Institute of Pediatric Hematology, Oncology and Immunology 10 participants Est. completion 2026-04 1 site Stand-aloneOther conditions: Severe Congenital Neutropenia, GATA2 DeficiencyView official trial listing → -
Suspended NCT NCT04855253
Ph I/II Study of E7777 Prior to CAR-T for R/R LBCL
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota 30 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: DLBCL, Diffuse Large B Cell Lymphoma, High-grade B-cell Lymphoma, DLBCL Arising From Follicular LymphomaView official trial listing → -
Active, not recruiting NCT NCT04859946
Itacitinib for the Prevention of Graft Versus Host Disease
Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2027-04-01 1 site Stand-aloneOther conditions: Hematologic and Lymphocytic DisorderView official trial listing → -
Withdrawn NCT NCT04860817
A Study of Anti-CD7 CAR-T Cells in Pediatric and Young Adult Patients With Relapse and Refractory T-ALL/ T-LBL
Not yet reported 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China Est. completion 2023-11-01 1 site Stand-aloneOther conditions: T-cell Acute Lymphoblastic Leukemia, T-lymphoblastic LymphomaView official trial listing → -
Status unknown NCT NCT04861480
Dual-target CAR-T Cells (C-4-29) in the Treatment of Relapsed/Refractory Multiple Myeloma
Not yet reported Chongqing Precision Biotech Co., Ltd 18 participants Est. completion 2024-07-18 1 site Stand-aloneOther conditions: Multiple Myeloma in Relapse, Multiple Myeloma, RefractoryView official trial listing → -
Active, not recruiting NCT NCT04872595
A Modified Dose of Rabbit Anti-thymocyte Globulin (rATG) in Children and Adults Receiving Treatment to Help Prepare Their Bodies for a Bone Marrow Transplant
Not yet reported Memorial Sloan Kettering Cancer Center 59 participants Est. completion 2027-04 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Acute Lymphoid Leukemia (ALL), Myelodysplastic Syndromes (MDS)View official trial listing → -
Active, not recruiting NCT NCT04877613
GFRα4 CAR T Cells in MTC Patients
Not yet reported University of Pennsylvania 9 participants Est. completion 2039-06-01 1 site Stand-aloneOther conditions: Metastatic Medullary Thyroid Cancer, Recurrent Thyroid Gland Medullary CarcinomaView official trial listing → -
Completed NCT NCT04880434
Study of Brexucabtagene Autoleucel (KTE-X19) in Participants With Relapsed/Refractory Mantle Cell Lymphoma (Cohort 3)
Not yet reported Kite, A Gilead Company 95 participants Est. completion 2025-06-17 40 sites Stand-aloneOther conditions: Relapsed/Refractory Mantle Cell LymphomaView official trial listing → -
Status unknown NCT NCT04888442
Phase I Study of pCAR-19B in the Treatment of Adult CD19-positive Relapsed/Refractory B-ALL
Not yet reported Chongqing Precision Biotech Co., Ltd 18 participants Est. completion 2022-03-28 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT04888468
Phase I Study of pCAR-19B in the Treatment of CD19-positive Relapsed/Refractory B-ALL in Children and Adolescents
Not yet reported Chongqing Precision Biotech Co., Ltd 9 participants Est. completion 2021-09-01 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Relapsed Pediatric ALL, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Withdrawn NCT NCT04893915
Cytokine-induced Memory-like NK Cells in Relapsed/Refractory AML and MDS
Not yet reported Washington University School of Medicine Est. completion 2024-12-31 Stand-aloneOther conditions: Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT04897139
Flu-Bu-Mel Based Conditioning Regimen for Patients With Lymphoid Malignancies Undergoing Allo-HSCT
Not yet reported Shanghai Jiao Tong University School of Medicine 23 participants Est. completion 2024-12-01 1 site Stand-aloneOther conditions: Lymphoid NeoplasmView official trial listing → -
Active, not recruiting NCT NCT04898894
Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia
Not yet reported St. Jude Children's Research Hospital 37 participants Est. completion 2027-09 8 sites Stand-aloneOther conditions: Acute Leukemia of Ambiguous Lineage in Relapse, Acute Myeloid Leukemia, in Relapse, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT04901416
Safety and Efficacy of Allogeneic NK Cell Infusions in Patients With Relapsed/Refractory AML and High Risk MDS
Not yet reported Coeptis Therapeutics 8 participants Est. completion 2024-06-04 1 site Stand-aloneOther conditions: AML, Adult Recurrent, MDSView official trial listing → -
Active, not recruiting NCT NCT04903080
HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma
Not yet reported Children's Oncology Group 50 participants Est. completion 2033-03-31 13 sites Stand-aloneOther conditions: EpendymomaView official trial listing → -
Terminated NCT NCT04904185
ImmPACT Expanded Multiple Antigen Specific Endogenously Derived T Cells (MASE-T) to Patients With Metastatic Melanoma
Not yet reported Inge Marie Svane 8 participants Est. completion 2024-06-07 1 siteOther conditions: Malignant MelanomaView official trial listing → -
Status unknown NCT NCT04904237
Aza-Ven Followed by Reduced Toxicity Conditioning Regimen (MBF) as Salvage Therapy for Refractory AML.
Not yet reported Shanghai Jiao Tong University School of Medicine 23 participants Est. completion 2024-06-01 3 sites Stand-aloneOther conditions: Refractory Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT04904588
HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide
Not yet reported Center for International Blood and Marrow Transplant Research 300 participants Est. completion 2026-12 39 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, LymphomaView official trial listing → -
Active, not recruiting NCT NCT04923893
A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy
Not yet reported Janssen Research & Development, LLC 743 participants Est. completion 2036-09-22 136 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT04933825
A Study of ET-02 in Patients With Relapsed or Refractory B-cell Malignancy(NHL/ALL)
Not yet reported EdiGene (GuangZhou) Inc. 18 participants Est. completion 2024-09-30 1 site Stand-aloneOther conditions: Relapsed or Refractory B-cell Malignancy(NHL/ALL)View official trial listing → -
Completed NCT NCT04938115
Cell Therapy for CD7 Positive Acute Myeloid Leukemia or Mixed Lineage Leukemia
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 50 participants Est. completion 2023-10-30 1 site Stand-aloneOther conditions: Leukemia, T CellView official trial listing → -
Completed NCT NCT04942730
Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe)
Not yet reported St. Petersburg State Pavlov Medical University 50 participants Est. completion 2024-04-30 1 site Stand-aloneOther conditions: Leukemia, Acute Lymphoblastic, Myeloid Leukemia, Acute, Biphenotypic Acute Leukemia, Lymphoblastic Lymphoma, Myelodysplastic Syndromes, Myeloproliferative NeoplasmView official trial listing → -
Completed NCT NCT04965597
Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)
Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2026-02-18 24 sites Stand-aloneOther conditions: Bone Marrow Failure Syndrome, Congenital Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Hereditary Sideroblastic Anemia, Paroxysmal Nocturnal Hemoglobinuria, Shwachman-Diamond Syndrome, Hematologic Neoplasm With Germline GATA2 Mutation, Hematologic Neoplasm With Germline SAMD9 Mutation, Hematologic Neoplasm With Germline SAMD9L MutationView official trial listing → -
Status unknown NCT NCT04973098
Phase I Clinical Trial of CT0181 Cells in the Treatment of Hepatocellular Carcinoma
Not yet reported Peking University 13 participants Est. completion 2023-06 1 site Stand-aloneOther conditions: Advanced Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT04980859
Zebutinib Combined With Immunochemotherapy in the Treat of Newly Treated CLL Patients Without 17p-/TP53 Mutation
Not yet reported Nanfang Hospital, Southern Medical University 45 participants Est. completion 2025-09-01 Stand-aloneOther conditions: Chronic Lymphocytic LeukemiaView official trial listing → -
Status unknown NCT NCT04981691
Anti-mesothelin CAR-T Cells With Advanced Refractory Solid Tumors
Not yet reported Ruijin Hospital 12 participants Est. completion 2022-07-09 1 site Stand-aloneOther conditions: Refractory Malignant Solid NeoplasmView official trial listing → -
Withdrawn NCT NCT04982354
Induction Therapy for Patients With FLT3 Mutated Acute Myeloid Leukemia
Not yet reported, Not yet reported Guenther Koehne Est. completion 2032-08-01 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT04989335
Bisantrene Combination for Resistant AML
Not yet reported Sheba Medical Center 29 participants Est. completion 2025-12-01 1 site Stand-aloneOther conditions: Myelogenous Leukemia, AcuteView official trial listing → -
Completed NCT NCT04990323
US Study of ECT-001-CB in Pediatric and Young Adult Patients With High-Risk Myeloid Malignancies
Not yet reported, Not yet reported ExCellThera inc. 13 participants Est. completion 2025-12-31 1 siteOther conditions: High Risk Myeloid Malignancies, Cord Blood TransplantView official trial listing → -
Terminated NCT NCT04994808
Treosulfan-Based Versus Clofarabine-Based Conditioning Before Donor Hematopoietic Stem Cell Transplant for the Treatment of Myelodysplastic Syndromes or Acute Myeloid Leukemia
Not yet reported Fred Hutchinson Cancer Center 23 participants Est. completion 2026-07-16 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Terminated NCT NCT05000450
Safety and Efficacy of ALLO-605 an Anti-BCMA Allogeneic CAR T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma
Not yet reported, Not yet reported Allogene Therapeutics 6 participants Est. completion 2023-10-11 4 sites Stand-aloneOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Terminated NCT NCT05001451
Study of GDX012 in Patients With MRD Positive AML
Not yet reported GammaDelta Therapeutics Limited 3 participants Est. completion 2022-06-03 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05005299
Venetoclax in Combination With Non-myeloablative Conditioning Allogeneic Haematopoietic Stem Cell Transplantation
Not yet reported Melbourne Health 18 participants Est. completion 2026-03-31 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Leukemia, Lymphoblastic, Acute, L1, Leukemia, Lymphoblastic, Acute, L2, Myelodysplastic Syndromes, Non-hodgkin Lymphoma, Plasma Cell MyelomaView official trial listing → -
Completed NCT NCT05007860
Vaccine Responsiveness in Patients With Chronic Lymphocytic Leukemia
Massachusetts General Hospital 36 participants Est. completion 2023-06-30 1 siteOther conditions: Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaView official trial listing → -
Status unknown NCT NCT05008536
Anti-BCMA CAR-NK Cell Therapy for the Relapsed or Refractory Multiple Myeloma
Not yet reported Xinqiao Hospital of Chongqing 27 participants Est. completion 2023-09-01 1 site Stand-aloneOther conditions: Multiple Myeloma, RefractoryView official trial listing → -
Status unknown NCT NCT05008575
Anti-CD33 CAR NK Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Xinqiao Hospital of Chongqing 27 participants Est. completion 2023-12-01 1 site Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Status unknown NCT NCT05016063
Dual CD33-CLL1-CAR-T Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Xinqiao Hospital of Chongqing 32 participants Est. completion 2023-09-01 1 site Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Active, not recruiting NCT NCT05020015
A Study of TAK-007 in Adults With Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)
Not yet reported Takeda 27 participants Est. completion 2038-12-20 15 sites Stand-aloneOther conditions: Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)View official trial listing → -
Status unknown NCT NCT05020392
Autologous Cells Derived Anti-CD19 CAR-Engineered T Cells With Concurrent BTK Inhibitor for B Cell Lymphoma
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 24 participants Est. completion 2024-10-13 1 site Stand-aloneOther conditions: Diffuse Large B Cell Lymphoma, Burkitt Lymphoma, Follicular Lymphoma, Chronic Lymphocytic Leukemia, Mantle Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT05020444
TriPRIL CAR T Cells in Multiple Myeloma
Not yet reported Marcela V. Maus, M.D.,Ph.D. 16 participants Est. completion 2028-02-24 1 site Stand-aloneOther conditions: Multiple Myeloma, Multiple Myeloma in Relapse, Refractory Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT05020678
NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers
Not yet reported Nkarta, Inc. 150 participants Est. completion 2038-12 6 sites Stand-aloneOther conditions: Lymphoma, Non-Hodgkin, B-cell Acute Lymphoblastic Leukemia, Large B-cell Lymphoma, Mantle Cell Lymphoma, Indolent Lymphoma, Waldenstrom Macroglobulinemia, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Aggressive Lymphoma, Large-cell LymphomaView official trial listing → -
Completed NCT NCT05022849
A Study of JNJ-75229414 for Metastatic Castration-resistant Prostate Cancer Participants
Not yet reported Janssen Research & Development, LLC 15 participants Est. completion 2026-03-11 8 sites Stand-aloneOther conditions: Prostatic NeoplasmsView official trial listing → -
Status unknown NCT NCT05028933
IMC001 for Clinical Research on Advanced Digestive System Malignancies
Not yet reported Zhejiang University 48 participants Est. completion 2024-12-31 2 sites Stand-aloneOther conditions: Advanced Hepatocellular Carcinoma, Advanced Colorectal Cancer, Advanced Gastric Cancer, Advanced Pancreatic CancerView official trial listing → -
Terminated NCT NCT05032599
Donor-Derived CD5 CAR T Cells in Subjects with Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia
Not yet reported Beijing Boren Hospital 19 participants Est. completion 2024-09-01 1 site Stand-aloneOther conditions: T-Cell Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT05032820
Upfront Chimeric Antigen Receptor T-Cell to Upgrade Response in Multiple Myeloma
Not yet reported Medical College of Wisconsin 40 participants Est. completion 2025-02-20 15 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Terminated NCT NCT05035407
T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers
Not yet reported National Cancer Institute (NCI) 36 participants Est. completion 2025-07-16 1 site Stand-aloneOther conditions: Kita-kyushu Lung Cancer Antigen 1, HumanView official trial listing → -
Completed NCT NCT05040568
A PHASE IB STUDY OF IMMUNOTHERAPY WITH EX VIVO PRE-ACTIVATED AND EXPANDED CB-NK CELLS IN COMBINATION WITH CETUXIMAB, IN COLORECTAL CANCER PATIENTS WITH MINIMAL RESIDUAL DISEASE (MRD)
Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2026-01-15 1 site Stand-aloneOther conditions: Colon Cancer, Resected StageView official trial listing → -
Terminated NCT NCT05050006
ITIL-168 in Advanced Melanoma
Not yet reported Instil Bio 29 participants Est. completion 2023-02-27 22 sites Stand-aloneOther conditions: Advanced Cutaneous MelanomaView official trial listing → -
Terminated NCT NCT05066165
Study Investigating NTLA-5001 in Subjects With Acute Myeloid Leukemia
Not yet reported, Not yet reported Intellia Therapeutics 6 participants Est. completion 2022-08-31 10 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT05069935
FT538 in Combination With Monoclonal Antibodies in Advanced Solid Tumors
Not yet reported Fate Therapeutics 16 participants Est. completion 2023-08-11 4 sites Stand-aloneOther conditions: Solid Tumor, AdultView official trial listing → -
Status unknown NCT NCT05084027
Venetoclax Combining With Fludarabine and Melphalan as Conditioning Regimen for Allo-HSCT
Not yet reported First Affiliated Hospital of Zhejiang University 50 participants Est. completion 2024-09-30 8 sites Stand-aloneOther conditions: Hematologic Malignancy, Older Patients, Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Active, not recruiting NCT NCT05088356
Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft
Not yet reported Stanford University 66 participants Est. completion 2028-05 1 site Stand-aloneOther conditions: Allogeneic Hematopoietic Cell Transplantation (HCT), Advanced Hematologic Malignancies, Acute Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndromes, Myeloproliferative DisordersView official trial listing → -
Withdrawn NCT NCT05114837
Ph I/II Study of CAR19 Regulatory T Cells (CAR19-tTreg) for R/R CD19+ B-ALL
Not yet reported, Not yet reported Masonic Cancer Center, University of Minnesota Est. completion 2028-08 1 site Stand-aloneOther conditions: Lymphoma LeukemiaView official trial listing → -
Completed NCT NCT05115630
Off-the-shelf NK Cells + SCT for Myeloid Malignancies
Not yet reported M.D. Anderson Cancer Center 24 participants Est. completion 2025-05-15 1 site Stand-aloneOther conditions: Myeloid Malignancies, Acute Myeloid Leukemia, Myelodysplastic Syndrome, Chronic Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05120271
BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors
Not yet reported, Not yet reported Sotio Biotech Inc. 7 participants Est. completion 2042-12 8 sites Stand-aloneObstructive sleep apnea Other conditions: Hepatocellular Carcinoma, Squamous Cell Carcinoma of the Lung, Merkel Cell CarcinomaView official trial listing → -
Status unknown NCT NCT05122221
CRTE7A2-01 TCR-T Cell for HPV-16 Positive Advanced Cervical, Anal, or Head and Neck Cancers
Not yet reported Corregene Biotechnology Co., Ltd 12 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Cervical Cancer, Anal Cancer, Head and Neck CancersView official trial listing → -
Not yet recruiting NCT NCT05126186
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation With Post-transplant Cyclophosphamide for Rescuing Patients With Graft Failure
Not yet reported Assistance Publique - Hôpitaux de Paris 35 participants Est. completion 2026-12-01 Stand-aloneOther conditions: Hematologic Diseases, Graft Failure, Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Suspended NCT NCT05138458
A Study of MT-101 in Subjects With CD5+ Relapsed/Refractory TCL
Not yet reported, Not yet reported Myeloid Therapeutics 40 participants Est. completion 2025-10 6 sites Stand-aloneOther conditions: Lymphoma, T-Cell, Peripheral, Lymphoma, T-Cell, Cutaneous, Mycosis Fungoides, Adoptive Cellular Immunotherapy, Cell TherapyView official trial listing → -
Active, not recruiting NCT NCT05139004
90Y-DOTA-anti-CD25 Basiliximab, Fludarabine, Melphalan, and Total Marrow and Lymphoid Irradiation for the Treatment of High-Risk Acute Leukemia or Myelodysplastic Syndrome
Not yet reported City of Hope Medical Center 7 participants Est. completion 2027-06-13 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome, Secondary Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05146739
Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane
Not yet reported National Cancer Institute (NCI) 8 participants Est. completion 2027-05-09 19 sites Stand-aloneOther conditions: Acute Myeloid Leukemia Post Cytotoxic Therapy, Myelodysplastic Syndrome Post Cytotoxic Therapy, Myeloid Leukemia Associated With Down Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Mixed Phenotype Acute Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Status unknown NCT NCT05155215
Study to Evaluate the Safety and Efficacy of IM19 CAR-T Cells in Patients With Relapsed and Refractory (R/R) Mantle Cell Lymphoma
Not yet reported, Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 68 participants Est. completion 2023-02-28 Stand-aloneOther conditions: Lymphoma, Lymphoma, Mantle-Cell, Neoplasms by Histologic Type, Neoplasms, Lymphoproliferative DisordersView official trial listing → -
Withdrawn NCT NCT05170828
Cryopreserved MMUD BM With PTCy for Hematologic Malignancies
Not yet reported Ossium Health, Inc. Est. completion 2024-11Other conditions: Acute Leukemia, Myelodysplastic Syndromes, T-lymphoblastic Lymphoma, Acute Lymphocytic Leukemia, Acute Myeloid Leukemia, Acute Biphenotypic Leukemia, Acute Undifferentiated LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05176470
Neoadj Admin Autologous Tumor Infiltrating Lymphocytes & Pembrolizumab for Treatment of Adv Melanoma Patients
Not yet reported Richard Wu 2 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Locally Advanced Melanoma, Pathologic Stage IIIB Cutaneous Melanoma AJCC v8, Pathologic Stage IIIC Cutaneous Melanoma AJCC v8, Pathologic Stage IIID Cutaneous Melanoma AJCC v8, Stage IV MelanomaView official trial listing → -
Completed NCT NCT05182073
FT576 in Subjects With Multiple Myeloma
Not yet reported Fate Therapeutics 31 participants Est. completion 2024-10-18 14 sites Stand-aloneOther conditions: Multiple Myeloma, MyelomaView official trial listing → -
Withdrawn NCT NCT05201183
A Dose Escalation Study of Intensity Modulated Total Marrow Irradiation (IMRT-TMI) Followed by Fludarabine as a Myeloablative Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Relapsed and Refractory Hematologic Malignancies
Not yet reported, Not yet reported Naoyuki G. Saito, M.D., Ph.D. Est. completion 2029-04 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Acute Lymphocytic Leukemia, Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT05206071
Clinical Study of SL19+22 CAR-T Cells for Relapsed or Refractory Non-Hodgkin Lymphoma
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 100 participants Est. completion 2023-12-31 1 site Stand-aloneOther conditions: Non-hodgkin's LymphomaView official trial listing → -
Terminated NCT NCT05207722
CYNK-101 in Combination with Trastuzumab and Pembrolizumab in Patients with Locally Advanced Unresectable or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma
Not yet reported, Not yet reported Celularity Incorporated 1 participants Est. completion 2024-02-15 3 sites Stand-aloneOther conditions: Metastatic HER2 Positive Gastroesophageal Junction CancerView official trial listing → -
Status unknown NCT NCT05208853
An Exploratory Clinical Study Evaluating the Safety and Efficacy of Anti CD30 CAR T Cells in Patients With CD30+ Relapsed/Refractory Lymphoma
Not yet reported Zhejiang University 9 participants Est. completion 2022-02-10 1 site Stand-aloneOther conditions: Hodgkin Lymphoma, NK/T Cell Lymphoma, Peripheral T Cell Lymphoma, Unspecified, Angioimmunoblastic T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Diffuse Large B Cell Lymphoma, Mediastinal B-Cell Diffuse Large Cell Lymphoma, Gray Zone LymphomaView official trial listing → -
Status unknown NCT NCT05211557
Study of Fully Human B7H3 CAR-T in Treating Recurrent Malignant Ovarian Cancer
Not yet reported, Not yet reported The Affiliated Hospital of Xuzhou Medical University 15 participants Est. completion 2026-08-31 1 site Stand-aloneOther conditions: Ovarian CancerView official trial listing → -
Withdrawn NCT NCT05218408
CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type
Not yet reported, Not yet reported Celularity Incorporated Est. completion 2021-10-23Other conditions: Astrocytoma, Grade IV, Glioblastoma, Giant Cell Glioblastoma, Glioblastoma MultiformeView official trial listing → -
Status unknown NCT NCT05225831
Safety and Efficacy of CD19/CD22 Dual Targeted CAR-T Cell Therapy in R/R B-Cell Acute Lymphoblastic Leukemia
Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 100 participants Est. completion 2023-11 1 site Stand-aloneOther conditions: CD19+ and CD 22+ B-ALLView official trial listing → -
Terminated NCT NCT05244070
A Study to Evaluate the Safety and Tolerability of BMS-986403 in Participants With Relapsed and/or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Not yet reported Bristol-Myers Squibb 5 participants Est. completion 2023-05-04 9 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-Cell, LymphomaView official trial listing → -
Withdrawn NCT NCT05248685
Optimized Dual CD33/CLL1 CAR T Cells in Subjects With Refractory or Relapsed Acute Myeloid Leukemia
Not yet reported Beijing Boren Hospital Est. completion 2023-12-31 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05250362
Ex Vivo Expanded NK Cells Infusion Decrease Relapse Post Hematopoietic Stem Cell Transplantation
Not yet reported, Not yet reported Sichuan University 56 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Hematologic MalignancyView official trial listing → -
Active, not recruiting NCT NCT05256537
Fludarabine and Total Body Irradiation 800 Centigray (cGy) or 1125 cGy For Allogeneic Stem Cell Transplant Using Graft Versus Host Disease Prophylaxis With Post-Transplant Cyclophosphamide and Tacrolimus, Without Mycophenolate Mofetil
Not yet reported Ronald Paquette 60 participants Est. completion 2027-01-07 1 siteOther conditions: Hematologic NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT05257083
A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma
Not yet reported Stichting European Myeloma Network 759 participants Est. completion 2040-08 106 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Withdrawn NCT NCT05266950
Safety and Efficacy Study of CI-135 CAR-T Cells in Subjects with Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported Beijing Boren Hospital Est. completion 2023-12-12 1 site Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05287984
Zanubrutinib Followed Zanubrutinib Plus FCR / BR in Newly Diagnosed Symptomatic CLL/SLL
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 63 participants Est. completion 2024-11-29 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Newly DiagnosedView official trial listing → -
Terminated NCT NCT05292898
A Triple-targeted Cell Preparation Targeting CD19/CD20/CD22 in Patients With Relapsed/Refractory B-cell Acute Lymphocytic Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 10 participants Est. completion 2025-03-31 2 sites Stand-aloneOther conditions: Acute Lymphocytic LeukemiaView official trial listing → -
Withdrawn NCT NCT05293509
Pharmacologic Pretransplant Immunosuppression (PTIS) + Reduced Toxicity Conditioning (RTC) Allogeneic Stem Cell Transplantation in Inherited Hematologic Disorders
Not yet reported M.D. Anderson Cancer Center Est. completion 2023-09-18 1 site Stand-aloneOther conditions: Stem Cell TransplantationView official trial listing → -
Terminated NCT NCT05298358
RIC alloBMT With Post-transplant Cyclophosphamide for Refractory Systemic Sclerosis
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 1 participants Est. completion 2024-11-21 1 site Stand-aloneOther conditions: Systemic SclerosisView official trial listing → -
Not yet recruiting NCT NCT05303727
Allogeneic Hematopoietic Stem Cell Transplantation for 4/M Neuroblastoma
Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 64 participants Est. completion 2027-08 1 site Stand-aloneOther conditions: NeuroblastomaView official trial listing → -
Status unknown NCT NCT05315778
Anti-BCMA CAR T-Cell Therapy for R/R ITP
Not yet reported The First Affiliated Hospital of Soochow University 5 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: ITPView official trial listing → -
Terminated NCT NCT05318963
Targeting CD19/CD20/CD22 Triple-targeted Cell in Patients With Relapsed/Refractory B-cell Lymphoma
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 14 participants Est. completion 2025-03-31 2 sites Stand-aloneOther conditions: B-cell Lymphoma Recurrent, B-cell Lymphoma RefractoryView official trial listing → -
Not yet recruiting NCT NCT05319249
Natural Killer Cell Immunotherapy in Combination With PARP-inhibition in Acute Myeloid Leukemia
Not yet reported, Not yet reported German Cancer Research Center 54 participants Est. completion 2028-06 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT05320380
A Study of the Drug IMGN632 in Children With Leukemia That Has Come Back After Treatment or is Difficult to Treat
Not yet reported, Not yet reported Children's Oncology Group Est. completion 2023-09-01 Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Recurrent B Acute Lymphoblastic Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Recurrent T Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia, Refractory B Acute Lymphoblastic Leukemia, Refractory Mixed Phenotype Acute Leukemia, Refractory T Acute Lymphoblastic LeukemiaView official trial listing → -
Completed NCT NCT05322330
Clinical Study of XPO-1 Inhibitors Plus CAR-T Cells in Relapsed Refractory B-cell Non-Hodgkin's Lymphoma
Not yet reported The First Affiliated Hospital of Soochow University 20 participants Est. completion 2024-02-10 1 siteOther conditions: Relapsed/Refractory B-cell Non-Hodgkin's LymphomaView official trial listing → -
Status unknown NCT NCT05322733
Orelabrutinib and Obinutuzumab Plus FC Regimen in Treating Newly Diagnosed CLL/SLL
Not yet reported The First Affiliated Hospital with Nanjing Medical University 25 participants Est. completion 2025-11-05 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT05326516
A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia
Not yet reported Syndax Pharmaceuticals 30 participants Est. completion 2024-07-29 11 sites Stand-aloneOther conditions: Relapsed/Refractory Leukemias, Acute Lymphoblastic Leukemia, Acute Lymphocytic Leukemia, Mixed Phenotype Acute Leukemia, Acute Myeloid Leukemia, Acute Undifferentiated LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05334329
Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors
Not yet reported University of California, Irvine 6 participants Est. completion 2028-11-30 1 site Stand-aloneOther conditions: Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Refractory Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8View official trial listing → -
Completed NCT NCT05347485
A Study of JNJ-68284528 Out-of-Specification (OOS) for Commercial Release in Participants With Multiple Myeloma
Not yet reported Janssen Scientific Affairs, LLC 86 participants Est. completion 2023-12-15 18 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT05352828
Autologous CD30.CAR-T in Combination With Nivolumab in cHL Patients After Failure of Frontline Therapy
Not yet reported Tessa Therapeutics 15 participants Est. completion 2037-12-15 5 sites Stand-aloneOther conditions: Classical Hodgkin Lymphoma, Hodgkin Disease Refractory, Hodgkin Disease RecurrentView official trial listing → -
Terminated NCT NCT05357027
HPV16 E6 TCR T Cells for Cervical Carcinoma
Not yet reported, Not yet reported TCRCure Biopharma Ltd. 5 participants Est. completion 2026-01-15 1 site Stand-aloneOther conditions: Cervical CarcinomaView official trial listing → -
Terminated NCT NCT05358808
ACHIEVE - Efficacy and Effectiveness of Adoptive Cellular tHerapy wIth Ex-Vivo Expanded Allogeneic γδ T-lymphocytes (TCB008) for Patients With Refractory or Relapsed Acute Myeloid Leukaemia (AML)
Not yet reported TC Biopharm 16 participants Est. completion 2025-07-30 6 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Completed NCT NCT05359211
NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma
Not yet reported Fred Hutchinson Cancer Center 27 participants Est. completion 2026-09-04 1 site Stand-aloneOther conditions: Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Recurrent Grade 3b Follicular Lymphoma, Recurrent Primary Mediastinal Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified, Refractory Grade 3b Follicular Lymphoma, Refractory Primary Mediastinal Large B-Cell Lymphoma, Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell LymphomaView official trial listing → -
Status unknown NCT NCT05370547
Chidamide Bridging for CAR-T Therapy
Not yet reported, Not yet reported Chinese PLA General Hospital 120 participants Est. completion 2025-06-30 13 sites Stand-aloneOther conditions: Non Hodgkin's LymphomaView official trial listing → -
Active, not recruiting NCT NCT05371093
Study of Axicabtagene Ciloleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Follicular Lymphoma
Not yet reported Kite, A Gilead Company 231 participants Est. completion 2030-10 52 sites Stand-aloneOther conditions: Relapsed/Refractory Follicular LymphomaView official trial listing → -
Status unknown NCT NCT05379569
Comparative Study of BFC and BuCy Conditioning Regimen for Allo-PBSCT in Acute B-cell ALL
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 142 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: Acute B Lymphoblastic Leukemia, Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Status unknown NCT NCT05379647
Natural Killer (NK) Cell Therapy for B-Cell Malignancies
Not yet reported Zhejiang University 24 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: B-cell Lymphoma, B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT05381181
Safety and Efficacy Evaluation of Next-generation CD19-UCART
Not yet reported Bioray Laboratories 20 participants Est. completion 2026-05-03 Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Non Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT05381662
CD19 Chimeric Antigen Receptors and CD19 Positive Feeder T Cells as a Leukemia Consolidation Treatment
Not yet reported, Not yet reported Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd 10 participants Est. completion 2025-12-01 3 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia in RemissionView official trial listing → -
Completed NCT NCT05390814
[18F]-Fludarabine PET/MRI in Primary Central Nervous System Lymphoma
Not yet reported Assistance Publique - Hôpitaux de Paris 10 participants Est. completion 2024-12-05 1 site Stand-aloneOther conditions: Primary Central Nervous System LymphomaView official trial listing → -
Withdrawn NCT NCT05393635
ITIL-168 in Advanced Solid Tumors
Not yet reported Instil Bio Est. completion 2022-12-08 Stand-aloneOther conditions: Cervical Cancer, Head and Neck Squamous Cell Carcinoma, Non-small Cell Lung CancerView official trial listing → -
Terminated NCT NCT05395052
FT536 Monotherapy and in Combination With Monoclonal Antibodies in Advanced Solid Tumors
Not yet reported Fate Therapeutics 5 participants Est. completion 2023-08-11 5 sites Stand-aloneOther conditions: Non Small Cell Lung Cancer, Colorectal Cancer, Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Head and Neck Cancer, GastroEsophageal CancerView official trial listing → -
Completed NCT NCT05396300
A Clinical Study of CEA-targeted CAR-T in the Treatment of CEA-positive Advanced Malignant Solid Tumors
Not yet reported Weijia Fang, MD 58 participants Est. completion 2026-06-30 1 site Stand-aloneOther conditions: Colorectal Cancer, Solid Cancers, Gastric CancerView official trial listing → -
Terminated NCT NCT05397093
ITIL-306 in Advanced Solid Tumors
Not yet reported Instil Bio 1 participants Est. completion 2026-03-06 2 sites Stand-aloneOther conditions: Epithelial Ovarian Cancer, Non-small Cell Lung Cancer, Renal Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05400109
Evaluate the Safety of UF-KURE19 Cells in Non-Hodgkin Lymphomas
Not yet reported David Wald 21 participants Est. completion 2026-10-01 3 sites Stand-aloneOther conditions: Non Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT05410041
Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory B-cell Malignancies
Not yet reported Beijing Boren Hospital 15 participants Est. completion 2024-05 1 site Stand-aloneOther conditions: Acute Lymphocytic Leukemia, Chronic Lymphocytic Leukemia, Non Hodgkin LymphomaView official trial listing → -
Completed NCT NCT05415475
Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced Malignant Solid Tumors
Not yet reported Chongqing Precision Biotech Co., Ltd 30 participants Est. completion 2025-09-15 1 site Stand-aloneOther conditions: Colorectal Cancer, Esophageal Cancer, Stomach Cancer, Pancreatic Cancer, Metastatic Tumor, Recurrent CancerView official trial listing → -
Status unknown NCT NCT05420493
Clinical Study of Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of Relapsed/Refractory Non-Hodgkin Lymphoma
Not yet reported Chongqing Precision Biotech Co., Ltd 54 participants Est. completion 2025-09-30 1 site Stand-aloneOther conditions: Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Non Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT05420519
Clinical Study of CD70-targeted CAR-T Therapy for Advanced/Advanced Renal Cancer
Not yet reported Chongqing Precision Biotech Co., Ltd 24 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Metastatic Tumor, Renal Cell Carcinoma, Advanced CancerView official trial listing → -
Status unknown NCT NCT05420545
A Clinical Study of CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors
Not yet reported Chongqing Precision Biotech Co., Ltd 36 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Metastatic Tumor, Advanced Solid Tumor, Renal Cell Carcinoma, Ovarian Cancer, Cervix CancerView official trial listing → -
Terminated NCT NCT05438667
TCR-T Cell Therapy on Advanced Solid Tumors
Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 1 participants Est. completion 2026-06-16 1 site Stand-aloneOther conditions: Pancreatic CancerView official trial listing → -
Status unknown NCT NCT05449899
G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for Secondary Acute Myeloid Leukemia Undergoing Allo-HSCT
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 232 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Secondary Acute Myeloid Leukemia Evolving From MDS, Allogeneic Hematopoietic Stem Cell Transplantation, ConditioningView official trial listing → -
Terminated NCT NCT05451849
A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer
Not yet reported, Not yet reported TCR2 Therapeutics 14 participants Est. completion 2025-08-30 7 sites Stand-aloneOther conditions: Mesothelioma, Mesotheliomas Pleural, Mesothelioma, Malignant, Mesothelioma Peritoneum, Ovarian Cancer, Ovarian Serous Adenocarcinoma, Pancreatic Cancer, Pancreatic Adenocarcinoma, Colorectal Cancer, Triple Negative Breast Cancer, TNBC - Triple-Negative Breast Cancer, Ovarian Adenocarcinoma, Pancreatic Neoplasms, Colorectal Neoplasms, Ovarian Neoplasms, Cholangiocarcinoma, Non Small Cell Lung CancerView official trial listing → -
Status unknown NCT NCT05453552
G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for High-risk MDS Undergoing Allo-HSCT
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 242 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome, Allogeneic Hematopoietic Stem Cell Transplantation, ConditioningView official trial listing → -
Status unknown NCT NCT05453669
Clinical Study of the Efficacy of CD19-CAR-DNT Cells in the Treatment of Relapsed/Refractory B-cell NHL
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 12 participants Est. completion 2025-06 1 site Stand-aloneOther conditions: B-cell Non-Hodgkin's LymphomaView official trial listing → -
Active, not recruiting NCT NCT05457010
Study of Cell Therapies for the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia or High-risk Myelodysplastic Syndrome.
Not yet reported Kite, A Gilead Company 24 participants Est. completion 2026-10 5 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromesView official trial listing → -
Active, not recruiting NCT NCT05457556
Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome
Not yet reported Children's Oncology Group 66 participants Est. completion 2027-07-07 63 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic SyndromeView official trial listing → -
Completed NCT NCT05459571
Study of Axicabtagene Ciloleucel Given With Steroids In Participants With Relapsed Or Refractory Large B-Cell Lymphoma
Not yet reported Kite, A Gilead Company 35 participants Est. completion 2025-11-24 16 sites Stand-aloneOther conditions: Relapsed or Refractory Large B-cell LymphomaView official trial listing → -
Status unknown NCT NCT05468190
A Clinical Research About CD70-positive Advanced/Metastatic Solid Tumors Treated by CD70-targeted CAR-T
Not yet reported Chongqing Precision Biotech Co., Ltd 48 participants Est. completion 2025-07-17 1 site Stand-aloneOther conditions: Metastatic Tumor, Advanced Solid Tumor, Renal Cell Carcinoma, Ovarian Cancer, Cervix CancerView official trial listing → -
Active, not recruiting NCT NCT05470283
Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma
Not yet reported M.D. Anderson Cancer Center 21 participants Est. completion 2027-04-01 1 site Stand-aloneOther conditions: Tumor, Metastatic Melanoma, MelanomaView official trial listing → -
Status unknown NCT NCT05472610
Study of Efficacy of BZ019 in Large B-cell Lymphoma
Not yet reported Shanghai Mengchao Cancer Hospital 36 participants Est. completion 2023-01 1 site Stand-aloneOther conditions: Large B-cell LymphomaView official trial listing → -
Terminated NCT NCT05478837
Genetically Modified Cells (KIND T Cells) for the Treatment of HLA-A*0201-Positive Patients With H3.3K27M-Mutated Glioma
Not yet reported University of California, San Francisco 4 participants Est. completion 2026-01-31 1 site Stand-aloneOther conditions: Diffuse Midline Glioma, H3 K27M-MutantView official trial listing → -
Withdrawn NCT NCT05487495
Donor-Derived CD5 CAR T (CT125B) Cells for Relapsed or Refractory T- Cell Acute Lymphoblastic Leukemia/Lymphoma
Not yet reported Beijing Boren Hospital Est. completion 2023-12-31 1 site Stand-aloneOther conditions: T-Cell Acute Lymphoblastic Leukemia/LymphomaView official trial listing → -
Status unknown NCT NCT05487651
Allogeneic NK T-Cells Expressing CD19 Specific CAR in B-Cell Malignancies
Not yet reported Athenex, Inc. 36 participants Est. completion 2024-12 3 sites Stand-aloneOther conditions: NHL, Relapsed, Adult, B-cell Lymphoma, B-cell Leukemia, DLBCL - Diffuse Large B Cell Lymphoma, ALL, Adult B Cell, ALL, Childhood, CLL/SLLView official trial listing → -
Active, not recruiting NCT NCT05495464
A Pilot "Window-3" Study of Acalabrutinib Plus Rituximab Followed by Brexucabtagene Autoleucel Therapy in Patients With Previously Untreated High-risk Mantle Cell Lymphoma
Not yet reported M.D. Anderson Cancer Center 22 participants Est. completion 2027-03-31 1 site Stand-aloneOther conditions: Lymphoma, Mantle Cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT05505812
Study on the Safety and Efficacy of Autogenous Tumor Infiltrates Lymphocytes for the Treatment of Advanced Breast Cancer
Not yet reported The Affiliated Hospital of Qingdao University 10 participants Est. completion 2027-03-31 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT05510505
GVHD Prophylaxis by Addition of CD20 Monoclonal Antibody to the Conditioning Regimen in SAA With Treatment of Allo-HSCT
Not yet reported The First Affiliated Hospital of Soochow University 100 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Withdrawn NCT NCT05513612
Novel CAR-T Cell Therapy in the Treatment of Hematopoietic and Lymphoid Malignancies
Not yet reported Shanghai Pudong Hospital Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), B-cell Non-Hodgkin's Lymphoma (B-NHL), Multiple Myeloma (MM), T-Cell Leukemia/Lymphoma, Adult, B-cell Acute Lymphoblastic Leukemia (B-ALL)View official trial listing → -
Status unknown NCT NCT05515185
B7-H3 Targeting CAR-T Cells Therapy for B7-H3 Positive Solid Tumors
Not yet reported The First People's Hospital of Lianyungang 30 participants Est. completion 2024-09-08 1 siteOther conditions: Advanced Solid TumorView official trial listing → -
Completed NCT NCT05518357
LILRB4 STAR-T Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Hebei Yanda Ludaopei Hospital 2 participants Est. completion 2022-11-15 1 site Stand-aloneOther conditions: Relapsed/Refractory Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05519384
Safety and Preliminary Efficacy of JK500 Cell Injection in Relapsed/Refractory Pediatric Acute Myeloid Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 12 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Childhood, Relapsed Leukemia, Refractory LeukemiaView official trial listing → -
Withdrawn NCT NCT05521087
A Study of JNJ-75276617 in Combination With Conventional Chemotherapy for Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias
Not yet reported Janssen Research & Development, LLC Est. completion 2030-01-29 Stand-aloneOther conditions: Acute Leukemias, Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Acute Leukemia of Ambiguous LineageView official trial listing → -
Status unknown NCT NCT05523661
Dasatinib Plus Anti-CD19/CD22 Bispecific CAR-T Cell Therapy for Elderly Ph-positive ALL Patients
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 15 participants Est. completion 2025-09-01 1 site Stand-aloneOther conditions: Ph Positive ALL, CAR-T Cell, DasatinibView official trial listing → -
Withdrawn NCT NCT05531708
Exploratory Study of Novel MSLN CAR-T Cell Therapy in Patients With MSLN-positive Advanced Refractory Solid Tumors
Not yet reported Shanghai Pudong Hospital Est. completion 2026-04-30 1 site Stand-aloneOther conditions: Mesothelin-positive Advanced Refractory Solid TumorsView official trial listing → -
Completed NCT NCT05534620
Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics
Not yet reported medac GmbH 20 participants Est. completion 2025-06-13 3 sites Stand-aloneOther conditions: Acute Myeloid Leukaemia (AML), Myelodysplastic Syndrome (MDS), Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)View official trial listing → -
Terminated NCT NCT05537766
Study of Brexucabtagene Autoleucel in Adults With Rare B-cell Malignancies
Not yet reported Kite, A Gilead Company 19 participants Est. completion 2025-01-27 26 sites Stand-aloneOther conditions: Relapsed/Refractory Waldenstrom Macroglobulinemia, Relapsed/Refractory Richter Transformation, Relapsed/Refractory Burkitt Lymphoma, Relapsed/Refractory Hairy Cell LeukemiaView official trial listing → -
Completed NCT NCT05538195
Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid Tumors
Not yet reported, Not yet reported Chongqing Precision Biotech Co., Ltd 17 participants Est. completion 2024-02-07 1 site Stand-aloneOther conditions: Gastric Cancer, Colon Cancer, Rectal Cancer, Esophageal Cancer, Pancreatic CancerView official trial listing → -
Not yet recruiting NCT NCT05539768
Study on the Safety and Efficacy of Autogenous Tumor Infiltrates Lymphocytes for the Treatment of Advanced Solid Tumor
Not yet reported The Affiliated Hospital of Qingdao University 8 participants Est. completion 2027-03-31 Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Completed NCT NCT05548088
LILRB4 STAR-T Cells in the Treatment of R/R AML/CMML
Not yet reported Peking University People's Hospital 11 participants Est. completion 2024-08-03 2 sites Stand-aloneOther conditions: Relapsed/Refractory Acute Myeloid Leukemia and Chronic Granulocytic-Mononocytic LeukemiaView official trial listing → -
Completed NCT NCT05563545
Anti-CD19 CAR-Engineered NK Cells in the Treatment of Relapsed/Refractory Acute Lymphoblastic Leukemia
Not yet reported Shanghai Simnova Biotechnology Co.,Ltd. 2 participants Est. completion 2022-11-25 1 site Stand-aloneOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT05565105
CD34+ Transplants for Leukemia and Lymphoma
Not yet reported Guenther Koehne 100 participants Est. completion 2033-06 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, AcuteView official trial listing → -
Withdrawn NCT NCT05566223
CISH Inactivated TILs in the Treatment of NSCLC
Not yet reported, Not yet reported Intima Bioscience, Inc. Est. completion 2027-11 2 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell Lung, Metastatic Non Small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer, Squamous Cell Lung Cancer, Adenocarcinoma of Lung, Large Cell Lung CancerView official trial listing → -
Terminated NCT NCT05569512
Uproleselan With Pre-Transplant Conditioning in Hematopoietic Stem Cell Transplantation for AML
Not yet reported Malika Kapadia 1 participants Est. completion 2023-12-06 5 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Pediatric CancerView official trial listing → -
Terminated NCT NCT05576077
A Study of TBio-4101 (TIL) and Pembrolizumab in Patients With Advanced Solid Tumors
Not yet reported Turnstone Biologics, Corp. 31 participants Est. completion 2025-02-24 13 sites Stand-aloneOther conditions: Breast Cancer, Colorectal Cancer, Uveal Melanoma, Cutaneous Melanoma, Non-Small Cell Lung Cancer, Head and Neck Squamous Cell CarcinomaView official trial listing → -
Status unknown NCT NCT05576181
Safety and Efficacy of ThisCART19A Bridging Hematopoietic Stem Cell Transplantation in Patients With Refractory or Relapsed B-cell Acute Lymphoblastic Leukemia
Not yet reported Fundamenta Therapeutics, Ltd. 19 participants Est. completion 2025-07-22 Stand-aloneOther conditions: Allogeneic, CAR-T, Protein Sequestration, Non-gene EditedView official trial listing → -
Active, not recruiting NCT NCT05577000
Anti-BCMA Chimeric Antigen Receptor T Cells for Relapsed or Refractory Multiple Myeloma
Not yet reported Thomas Martin, MD 5 participants Est. completion 2038-08-31 1 site Stand-aloneOther conditions: Refractory Multiple Myeloma, Relapsed Multiple MyelomaView official trial listing → -
Status unknown NCT NCT05578378
Cladribine Combined With G-CSF and Cytarabine as a Salvage Treatment in R/R ALL
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 32 participants Est. completion 2024-12-31 1 siteOther conditions: Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT05579769
Pediatric Study of GVHD Ppx w/o Calcineurin Inhibitors After Day60 Post First Allo HSCT for Hematological Malignancies.
Not yet reported St. Jude Children's Research Hospital 3 participants Est. completion 2024-05-08 1 site Stand-aloneOther conditions: Hematologic Malignancy, Myeloid MalignancyView official trial listing → -
Not yet recruiting NCT NCT05582590
Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal Cancers
Not yet reported NexImmune Inc. 36 participants Est. completion 2027-08-25 Stand-aloneObstructive sleep apnea Other conditions: Oropharyngeal Cancer, Human Papilloma Virus, Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma, Oropharyngeal Cancer, Metastatic, Head and Neck Cancer Metastatic, HPV-Related Squamous Cell Carcinoma, Relapsed Oropharyngeal SCC, Refractory Oropharyngeal Squamous Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05583149
Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas
Not yet reported Patrick C. Johnson, MD 28 participants Est. completion 2029-03-01 2 sites Stand-aloneOther conditions: Refractory Aggressive B-cell Lymphomas, Refractory B-Cell Non-Hodgkin Lymphoma, Aggressive B-cell NHL, Diffuse Large B-cell Lymphoma (DLBCL), De Novo or Transformed Indolent B-cell Lymphoma, DLBCL, Nos Genetic Subtypes, T Cell/Histiocyte-rich Large B-cell Lymphoma, EBV-Positive DLBCL, Nos, Primary Mediastinal [Thymic] Large B-cell Lymphoma (PMBCL), High-Grade B-Cell Lymphoma, Nos, C-MYC/BCL6 Double-Hit High-Grade B-Cell Lymphoma, Grade 3b Follicular Lymphoma, C-MYC/BCL2 Double-Hit High-Grade B-Cell LymphomaView official trial listing → -
Status unknown NCT NCT05583175
Venetoclax Plus RIC Regimen Allo-HSCT for Elderly Patients With High-risk Myeloid Malignancies
Not yet reported Xianmin Song, MD 50 participants Est. completion 2024-11-01 1 site Stand-aloneOther conditions: Leukemia, Myeloid, Acute, MDS, Hematopoietic Stem Cell Transplantation, Myeloid MalignancyView official trial listing → -
Terminated NCT NCT05588440
A Clinical Study of ONCT-808 in Subjects With Relapsed or Refractory B-Cell Malignancies
Not yet reported, Not yet reported Oncternal Therapeutics, Inc 9 participants Est. completion 2024-09-12 4 sites Stand-aloneOther conditions: Relapsed/Refractory Aggressive B-Cell MalignanciesView official trial listing → -
Active, not recruiting NCT NCT05589896
A First-in-Human Study of HLA-Partially to Fully Matched Allogenic Cryopreserved Deceased Donor Bone Marrow Transplantation for Patients With Hematologic Malignancies
Not yet reported, Not yet reported Ossium Health, Inc. 12 participants Est. completion 2029-05-31 9 sites Stand-aloneOther conditions: Acute Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Biphenotypic Leukemia, Acute Undifferentiated Leukemia, CLL (Chronic Lymphocytic Leukemia), Chronic Myeloid Leukemia (CML), MDS (Myelodysplastic Syndrome), Non-Hodgkin Lymphomas, Hodgkins Lymphoma, Cutaneous T Cell Lymphomas (CTCL)View official trial listing → -
Status unknown NCT NCT05590221
Relmacabtagene Autoleucel as First-Line Therapy for High-Risk Large B-Cell Lymphoma
Not yet reported Peking University Cancer Hospital & Institute 20 participants Est. completion 2024-12-10 4 sites Stand-aloneOther conditions: B-cell LymphomaView official trial listing → -
Status unknown NCT NCT05598593
Modified TBF Regimen as Conditioning Regimen Prior to Allo-HSCT for T-ALL/LBL
Not yet reported First Affiliated Hospital of Zhejiang University 70 participants Est. completion 2025-09 1 site Stand-aloneOther conditions: Cytarabine+Thiotepa + Fludarabine + Busulfan, T Cell Acute Lymphoblastic Leukemia/Lymphoblastic LymphomaView official trial listing → -
Active, not recruiting NCT NCT05600426
A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)
Not yet reported Boston Children's Hospital 53 participants Est. completion 2029-12 52 sitesOther conditions: Severe Aplastic AnemiaView official trial listing → -
Terminated NCT NCT05601830
Natural Killer(NK) Cell Therapy for AML Minimal Residual Disease
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 1 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: Minimal Residual DiseaseView official trial listing → -
Active, not recruiting NCT NCT05605899
Study to Compare Axicabtagene Ciloleucel With Standard of Care Therapy as First-line Treatment in Participants With High-risk Large B-cell Lymphoma
Not yet reported Kite, A Gilead Company 300 participants Est. completion 2031-03 85 sites Stand-aloneOther conditions: High-risk Large B-cell Lymphoma (LBCL)View official trial listing → -
Withdrawn NCT NCT05613348
CD19 CAR T-cell Target Relapsed/Refractory Acute B Cell Leukemia/Lymphoma
Not yet reported, Not yet reported Zhujiang Hospital Est. completion 2028-12-01 2 sites Stand-aloneOther conditions: B-cell Acute Lymphoblastic Leukemia, B-Cell Lymphoma, UnspecifiedView official trial listing → -
Status unknown NCT NCT05616468
BGT007 Cell Treatment of Nasopharyngeal Carcinoma
Not yet reported The Affiliated Hospital of Xuzhou Medical University 23 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Nasopharyngeal CarcinomaView official trial listing → -
Suspended NCT NCT05617625
CD34+ Enriched Transplants to Treat Myelodysplastic Syndrome
Not yet reported Guenther Koehne 50 participants Est. completion 2033-06 1 site Stand-aloneOther conditions: Myelodysplastic Syndromes, Graft Vs Host Disease, Graft-versus-host-diseaseView official trial listing → -
Active, not recruiting NCT NCT05617755
AB-1015, an Integrated Circuit T (ICT) Cell Therapy in Patients With Platinum Resistant Epithelial Ovarian Cancer
Not yet reported Arsenal Biosciences, Inc. 19 participants Est. completion 2027-02 8 sites Stand-aloneOther conditions: Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms, Neoplasms, Glandular and Epithelial, Ovarian Diseases, Genital Neoplasm, Female, Abdominal Neoplasm, RecurrenceView official trial listing → -
Active, not recruiting NCT NCT05621096
Low Dose Radiation as Bridging Therapy in Relapsed B-Cell Non-Hodgkin Lymphoma
Not yet reported University of Nebraska 33 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: DLBCL - Diffuse Large B Cell Lymphoma, High-grade B-cell Lymphoma, Follicular Lymphoma, Mediastinal Large B-cell Lymphoma, Indolent B-Cell Non-Hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin LymphomaView official trial listing → -
Active, not recruiting NCT NCT05624554
A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008)
Not yet reported Merck Sharp & Dohme LLC 300 participants Est. completion 2031-03-17 97 sitesOther conditions: Chronic Lymphocytic Leukemia, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT05628883
Proof of Concept of TBio-4101, Lymphodepleting Chemo, IL-2 for Relapsed/Refractory Melanoma
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 17 participants Est. completion 2025-03-06 1 site Stand-aloneObstructive sleep apnea Other conditions: Metastatic Melanoma, Unresectable Melanoma, Acral Melanoma, Cutaneous Melanoma, Ocular Melanoma, Uveal Melanoma, Iris Melanoma, Conjunctival Melanoma, Non-Cutaneous MelanomaView official trial listing → -
Status unknown NCT NCT05631912
TRAC Locus-inserted CD19-targeting STAR-T Cell Therapy in r/r B-NHL
Not yet reported, Not yet reported Chinese PLA General Hospital 38 participants Est. completion 2025-12-15 2 sites Stand-aloneOther conditions: Non-hodgkin Lymphoma,B CellView official trial listing → -
Completed NCT NCT05634785
CD30 CAR for CD30+ NSGCT
Not yet reported UNC Lineberger Comprehensive Cancer Center 2 participants Est. completion 2025-12-18 1 site Stand-aloneOther conditions: Germ Cell Tumor, Nonseminomatous Germ Cell TumorView official trial listing → -
Status unknown NCT NCT05645601
CAR-NK Targeted CD19 for r/r B-cell Malignancies
Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 12 participants Est. completion 2024-12-30 1 site Stand-aloneOther conditions: Adult Relapsed/Refractory B-cell Hematologic MalignanciesView official trial listing → -
Status unknown NCT NCT05648994
TCR-T Cells for the Treatment NY-ESO-1-positive Advanced Solid Tumors
Not yet reported Fujian Cancer Hospital 30 participants Est. completion 2026-03 Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Status unknown NCT NCT05651100
Safety and Efficacy of Sequential CD19 and CD22 Targeted CAR-T Therapy for Relapsed/Refractory B Cell Lymphoma
Not yet reported, Not yet reported Kecellitics Biotech Company Ltd 50 participants Est. completion 2025-12-10 1 site Stand-aloneOther conditions: Lymphoma, B-CellView official trial listing → -
Completed NCT NCT05653271
ACE1831 in Adult Subjects With Relapsed/ Refractory CD20-expressing B-cell Malignancies
Not yet reported Acepodia Biotech, Inc. 16 participants Est. completion 2026-03-31 13 sites Stand-aloneOther conditions: B-cell Lymphoma, Non Hodgkin Lymphoma, DLBCL, Primary Mediastinal Large B Cell Lymphoma, Marginal Zone Lymphoma, Follicular Lymphoma, Burkitt Lymphoma, High-grade B-cell LymphomaView official trial listing → -
Status unknown NCT NCT05654077
EBV CAR-T Cells for Nasopharyngeal Carcinoma
Not yet reported The Affiliated Hospital of Xuzhou Medical University 24 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: Nasopharyngeal CarcinomaView official trial listing → -
Not yet recruiting NCT NCT05662904
Genetic Ablation of CD33 in HSC to Broaden the Therapeutic Index of CD33-directed Immunotherapy in Patients with AML
Not yet reported German Cancer Research Center 12 participants Est. completion 2030-01 2 sites Stand-aloneOther conditions: Relapsed/Refractory Acute Myeloid Leukemia (AML)View official trial listing → -
Active, not recruiting NCT NCT05665062
Autologous CD19 CAR-T Cell Therapy (SYNCAR-001) + Orthogonal IL-2 (STK-009) in Subjects With CD19+ Hematologic Malignancies
Not yet reported Synthekine 36 participants Est. completion 2041-11 4 sites Stand-aloneOther conditions: CLL/SLL, NHL, Mantle Cell Lymphoma, Follicular Lymphoma, Large B-cell Lymphoma, Indolent B-Cell Non-Hodgkin Lymphoma, Diffuse Large B Cell LymphomaView official trial listing → -
Status unknown NCT NCT05665114
Natural Killer(NK) Cell Therapy in r/r AML
Not yet reported Zhejiang University 18 participants Est. completion 2025-12-24 1 site Stand-aloneOther conditions: AML, AdultView official trial listing → -
Status unknown NCT NCT05667402
Clinical Study of TBF Regimen in Allo-HSCT in Patients With CNS Leukemia
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 50 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Central Nervous System Leukemia, Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Active, not recruiting NCT NCT05672173
Lisocabtagene Maraleucel, Nivolumab and Ibrutinib for the Treatment of Richter's Transformation
Not yet reported City of Hope Medical Center 9 participants Est. completion 2027-08-24 2 sites Stand-aloneOther conditions: Recurrent Transformed Chronic Lymphocytic Leukemia, Refractory Transformed Chronic Lymphocytic Leukemia, Richter SyndromeView official trial listing → -
Active, not recruiting NCT NCT05672459
A Safety And Efficacy Study Of HLA-G- Targeted CAR-T Cells IVS-3001 In Subjects With Previously Treated Advanced HLA-G-Positive Solid Tumors
Not yet reported, Not yet reported M.D. Anderson Cancer Center 31 participants Est. completion 2028-12-29 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Status unknown NCT NCT05673447
The Study of Anti-CD19 CAR NK Cells in the Treatment of Relapsed/Refractory Diffuse Large B Cell Lymphoma
Not yet reported Changhai Hospital 12 participants Est. completion 2024-12-30 1 site Stand-aloneOther conditions: Diffuse Large B Cell LymphomaView official trial listing → -
Enrolling by invitation NCT NCT05674539
Reduced Intensity Conditioning Regimens for Acute Myeloid Leukemia and Myelodysplastic Syndrome
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 200 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Adult, Myelodysplastic Syndrome(MDS), Allogeneic Hematopoietic Stem Cell TransplantationView official trial listing → -
Withdrawn NCT NCT05678205
A Clinical Trial of the Safety and Anti-Tumor Activity of AB-201 in Subjects With Advanced HER2+ Solid Tumors
Not yet reported, Not yet reported Artiva Biotherapeutics, Inc. Est. completion 2027-04 2 sites Stand-aloneOther conditions: Breast Cancer, Gastric Cancer, Gastroesophageal Junction AdenocarcinomaView official trial listing → -
Status unknown NCT NCT05679687
ThisCART19A Bridging to alloHSCT for R/R B-ALL
Not yet reported The First Affiliated Hospital of Soochow University 20 participants Est. completion 2025-11-30 1 site Stand-aloneOther conditions: CAR, Refractory Acute Lymphoblastic Leukemia, Relapsed Adult ALLView official trial listing → -
Status unknown NCT NCT05691153
ThisCART19A for B-NHL Relapsed After Auto-CAR T
Not yet reported The First Affiliated Hospital of Soochow University 20 participants Est. completion 2025-11-30 1 site Stand-aloneOther conditions: CAR, B Cell Lymphoma, Relapsed Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT05694364
Dose Escalation/Dose Expansion Study of PRGN-3007 UltraCAR-T Cells in Patients With Advanced Hematologic and Solid Tumor Malignancies
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 3 participants Est. completion 2024-04-18 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma, Acute Lymphoblastic Leukemia, Diffuse Large B Cell Lymphoma, Triple Negative Breast Cancer MalignanciesView official trial listing → -
Suspended NCT NCT05703854
Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 50 participants Est. completion 2027-09-30 1 site Stand-aloneObstructive sleep apnea Other conditions: Advanced Renal Cell Carcinoma, Advanced MesotheliomaView official trial listing → -
Active, not recruiting NCT NCT05707273
CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remission
Not yet reported City of Hope Medical Center 18 participants Est. completion 2026-09-22 1 site Stand-aloneOther conditions: B Acute Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT05712278
A Study to Investigate Use of Off-the-shelf Natural Killer (NK) Cells (SAR445419) in Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Sanofi 7 participants Est. completion 2024-03-12 3 sites Stand-aloneOther conditions: Acute Myeloid LeukaemiaView official trial listing → -
Terminated NCT NCT05714345
Evaluation of Lymphodepletion With ALLO-647 in Adults With R/R Large B Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy
Not yet reported Allogene Therapeutics 2 participants Est. completion 2024-10-28 2 sites Stand-aloneOther conditions: Relapsed/Refractory Large B Cell LymphomaView official trial listing → -
Status unknown NCT NCT05715606
Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of r/r DLBCL Clinical Research
Not yet reported Anhui Provincial Hospital 18 participants Est. completion 2025-05-15 1 site Stand-aloneOther conditions: Diffuse Large B-cell LymphomaView official trial listing → -
Completed NCT NCT05739409
LILRB4 STAR-T Cell Therapy for Monocytic Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 1 participants Est. completion 2023-05-09 2 sites Stand-aloneOther conditions: Acute Myelogenous Leukemia, Chronic Myelomonocytic LeukemiaView official trial listing → -
Status unknown NCT NCT05739630
M-PTCy vs BuCy in Haploidentical HSCT for Acute Leukemia
Not yet reported, Not yet reported The First Affiliated Hospital of Soochow University 60 participants Est. completion 2025-01-31 1 siteOther conditions: Acute LeukemiaView official trial listing → -
Status unknown NCT NCT05744037
Clinical Study of the Safety and Efficacy of the R/R B-NHL Regimen With BTK Inhibitor+Anti-CD19 CAR-T Cells
Not yet reported The Affiliated Hospital of Xuzhou Medical University 30 participants Est. completion 2025-01-01 1 site Stand-aloneOther conditions: B-cell Non Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT05747157
Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10- 19) in the Treatment of r/r B-ALL Clinical Research
Not yet reported Anhui Provincial Hospital 18 participants Est. completion 2025-05-15 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT05755854
Allogeneic γ9δ2 T Cells Treatment of Recurrent Hematologic Tumors
Not yet reported Anhui Provincial Hospital 10 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Hematologic DiseasesView official trial listing → -
Active, not recruiting NCT NCT05761171
A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia
Not yet reported Children's Oncology Group 78 participants Est. completion 2027-12-31 84 sites Stand-aloneOther conditions: Recurrent Acute Leukemia of Ambiguous Lineage, Recurrent Acute Lymphoblastic Leukemia, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged, Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia, Recurrent Mixed Phenotype Acute Leukemia, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic Leukemia, KMT2A-Rearranged, Refractory Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute Leukemia, Refractory Mixed Phenotype Acute LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05767359
CAR- PRISM (PRecision Intervention Smoldering Myeloma)
Not yet reported Dana-Farber Cancer Institute 20 participants Est. completion 2040-01-15 1 site Stand-aloneOther conditions: Multiple Myeloma, Smoldering Multiple MyelomaView official trial listing → -
Status unknown NCT NCT05775666
UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors
Not yet reported Peking University 87 participants Est. completion 2025-01 Stand-aloneOther conditions: Solid TumorView official trial listing → -
Status unknown NCT NCT05776407
Safety, Efficacy and Pharmacokinetics of ThisCART19A in Patients With Refractory or Relapsed B Cell Lymphoma
Not yet reported, Not yet reported Chongqing University Cancer Hospital 12 participants Est. completion 2024-11 1 site Stand-aloneOther conditions: Refractory or Relapsed B Cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT05779930
Safety and Feasibility of CD19 CAR T Cells Using CliniMACS Prodigy for Relapsed/Refractory CD19 Positive ALL and NHL
Not yet reported Nationwide Children's Hospital 12 participants Est. completion 2035-12 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, in Relapse, Non-Hodgkin's Lymphoma, Relapsed, Non-Hodgkin's Lymphoma Refractory, Acute Lymphoblastic Leukemia With Failed Remission, B-cell Non Hodgkin Lymphoma, B Cell LeukemiaView official trial listing → -
Terminated NCT NCT05780879
A Proof of Concept Pilot Study of the Addition of Venetoclax to Standard Remission Induction Chemotherapy Fludarabine or Cladrabine, Cytarabine, and Granulocyte Colony Stimulating Factor (G-CSF) (FLAG or CLAG) for Frontline Therapy of Secondary Acute Myeloid Leukemia
Not yet reported University of Michigan Rogel Cancer Center 10 participants Est. completion 2025-08-16 1 site Stand-aloneOther conditions: Secondary Acute Myeloid LeukemiaView official trial listing → -
Status unknown NCT NCT05787535
HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid Tumor
Not yet reported HRYZ Biotech Co. 17 participants Est. completion 2025-09 1 site Stand-aloneOther conditions: Cervical Cancer, Head and Neck Squamous Cell Carcinoma, Oropharyngeal Cancer, Vagina Tumor, Carcinoma of Penis, Anal Carcinoma, Carcinoma of VulvaView official trial listing → -
Active, not recruiting NCT NCT05797233
Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies
Not yet reported National Cancer Institute (NCI) 58 participants Est. completion 2029-12-30 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, B-Cell Chronic Lymphocytic Leukemia, Lymphoma, B-CellView official trial listing → -
Status unknown NCT NCT05797948
GZL Sequential CD19/CD22 CAR-T in Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported The First Affiliated Hospital of Soochow University 20 participants Est. completion 2024-06-30 1 site Stand-aloneOther conditions: Relapsed or Refractory B-cell Non-Hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT05798546
Treatment of Advanced Solid Tumors With Neo-T(GI-NeoT-02)
Not yet reported BGI, China 21 participants Est. completion 2024-09 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Status unknown NCT NCT05807659
Fractionated Busulfan Conditioning Regimen for Allo-HSCT in Non-remission Myeloid Malignancies
Not yet reported Sichuan University 18 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Myeloid MalignanciesView official trial listing → -
Status unknown NCT NCT05848999
UCLM802 (Anti-Mesothelin CAR-T) Cell Injection in Patients With Mesothelin-positive Advanced Malignant Solid Tumors
Not yet reported Zhejiang University 87 participants Est. completion 2025-07 1 site Stand-aloneOther conditions: Mesothelin-positive Advanced Malignant Solid TumorsView official trial listing → -
Active, not recruiting NCT NCT05862324
TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3)
Not yet reported, Not yet reported Triumvira Immunologics, Inc. 113 participants Est. completion 2027-08-01 9 sites Stand-aloneOther conditions: Metastatic Solid TumorView official trial listing → -
Terminated NCT NCT05868915
HV-101 for Patients With Advanced Solid Tumors
Not yet reported Hervor Therapeutics 1 participants Est. completion 2026-01-15 1 site Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Active, not recruiting NCT NCT05869955
A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 270 participants Est. completion 2028-08-29 46 sites Stand-aloneOther conditions: Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathy, Systemic Sclerosis, Rheumatoid ArthritisView official trial listing → -
Not yet recruiting NCT NCT05876832
A Study of XY0206 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory AML With FLT3-ITD-Mutation (ALIVE)
Not yet reported Shijiazhuang Yiling Pharmaceutical Co. Ltd 312 participants Est. completion 2027-07-01Other conditions: Acute Myeloid Leukemia With FLT3/ITD MutationView official trial listing → -
Active, not recruiting NCT NCT05878184
Study Evaluating SC291 in Subjects With r/r B-cell Malignancies (ARDENT)
Not yet reported Sana Biotechnology 16 participants Est. completion 2038-11-04 10 sites Stand-aloneOther conditions: Non Hodgkin Lymphoma, Chronic Lymphocytic LeukemiaView official trial listing → -
Terminated NCT NCT05883449
Phase 2 Study of AFM13 in Combination With AB-101 in Subjects With R/R HL and CD30+ PTCL
Not yet reported Affimed GmbH 25 participants Est. completion 2025-06-13 15 sites Stand-aloneOther conditions: Relapsed or Refractory Hodgkin Lymphoma, Peripheral T Cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT05885464
A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)
Not yet reported, Not yet reported Beam Therapeutics Inc. 5 participants Est. completion 2026-12 10 sites Stand-aloneOther conditions: Lymphoblastic Lymphoma, T-Cell Lymphoblastic Leukemia/Lymphoma, Lymphoblastic LeukemiaView official trial listing → -
Terminated NCT NCT05886491
A Study of GDX012 in Adults With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported Takeda 16 participants Est. completion 2025-11-30 11 sites Stand-aloneOther conditions: LeukemiaView official trial listing → -
Active, not recruiting NCT NCT05907746
Allogeneic Hematopoietic Stem Cell Transplantation With Briquilimab-Based Conditioning in Participants With GATA2 Deficiency
Not yet reported National Cancer Institute (NCI) 13 participants Est. completion 2028-07-31 1 site Stand-aloneOther conditions: GATA2, ImmunodeficiencyView official trial listing → -
Active, not recruiting NCT NCT05922930
Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer
Not yet reported, Not yet reported M.D. Anderson Cancer Center 51 participants Est. completion 2028-01-15 1 site Stand-aloneOther conditions: Pancreatic Cancer, Ovarian Cancer, AdenocarcinomaView official trial listing → -
Status unknown NCT NCT05929092
TFBC Combined With UCBT in the Treatment of High-risk Malignant Hematological Diseases
Not yet reported The First Affiliated Hospital of Soochow University 40 participants Est. completion 2026-05-31 1 siteOther conditions: Hematopoietic Stem Cell Transplantation, Malignant Hematological DiseasesView official trial listing → -
Status unknown NCT NCT05930314
CNCT19 Cell Injection for Refractory Systemic Lupus Erythematosus
Not yet reported Peking Union Medical College Hospital 12 participants Est. completion 2025-05-30 1 site Stand-aloneOther conditions: Refractory Systemic Lupus Erythematosus, Lupus Nephritis, Immune ThrombocytopeniaView official trial listing → -
Status unknown NCT NCT05933668
Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Solid Tumor
Not yet reported Peking University 11 participants Est. completion 2026-07 1 site Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Withdrawn NCT NCT05936229
Interferon-Beta-1a (FP-1201) to Prevent Toxicities After CD19-Directed CAR T-Cell Therapy
Not yet reported, Not yet reported Fred Hutchinson Cancer Center Est. completion 2027-10-30 1 site Stand-aloneOther conditions: Recurrent B Acute Lymphoblastic Leukemia, Recurrent B-Cell Non-Hodgkin Lymphoma, Refractory B Acute Lymphoblastic Leukemia, Refractory B-Cell Non-Hodgkin Lymphoma, Recurrent Mantle Cell Lymphoma, Refractory Mantle Cell LymphomaView official trial listing → -
Terminated NCT NCT05938725
KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis
Not yet reported, Not yet reported Kyverna Therapeutics 6 participants Est. completion 2026-05-29 6 sitesOther conditions: Lupus Nephritis, Lupus Nephritis - World Health Organization (WHO) Class III, Lupus Nephritis - WHO Class IVView official trial listing → -
Status unknown NCT NCT05941156
Clinical Study of Anti-CD56-CAR-T in the Treatment of Relapsed/Refractory NK/T Cell Lymphoma /NK Cell Leukemia
Not yet reported The Affiliated Hospital of Xuzhou Medical University 20 participants Est. completion 2026-05 1 site Stand-aloneOther conditions: Extranodal NK T Cell Lymphoma, NK-Cell LeukemiaView official trial listing → -
Status unknown NCT NCT05941936
A Clinical Study on LM103 for the Treatment of Advanced Solid Tumors
Not yet reported Suzhou BlueHorse Therapeutics Co., Ltd. 5 participants Est. completion 2026-02 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Terminated NCT NCT05943990
Study of GSK3845097 in Previously Treated Participants With Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma
Not yet reported Adaptimmune 5 participants Est. completion 2022-10-24 21 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Withdrawn NCT NCT05950113
CART-BCMA/CS1 in Treating Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported Jonsson Comprehensive Cancer Center Est. completion 2028-03-28 1 site Stand-aloneOther conditions: Recurrent Multiple Myeloma, Refractory Multiple MyelomaView official trial listing → -
Completed NCT NCT05950334
FT522 With Rituximab in Relapsed/Refractory B-Cell Lymphoma (FT522-101)
Not yet reported Fate Therapeutics 20 participants Est. completion 2025-06-30 7 sites Stand-aloneOther conditions: Relapsed/Refractory B-Cell LymphomaView official trial listing → -
Status unknown NCT NCT05971576
A Clinical Study on TILs for the Treatment of Advanced Solid Tumors
Not yet reported Suzhou BlueHorse Therapeutics Co., Ltd. 20 participants Est. completion 2026-08 Stand-aloneOther conditions: Solid TumorView official trial listing → -
Status unknown NCT NCT05971589
A Clinical Study on LM103 Injection for the Treatment of Advanced Solid Tumors
Not yet reported Suzhou BlueHorse Therapeutics Co., Ltd. 5 participants Est. completion 2026-08 Stand-aloneOther conditions: Solid TumorView official trial listing → -
Terminated NCT NCT05972720
A Phase 2 Study of Firi-cel in Patients With Relapsed/Refractory Large B-cell Lymphoma
Not yet reported CARGO Therapeutics 101 participants Est. completion 2025-04-04 31 sites Stand-aloneOther conditions: Cancer, Relapsed/Refractory Large B-cell Lymphoma (LBCL)View official trial listing → -
Status unknown NCT NCT05976906
Universal Dual-target NKG2D-NKp44 CAR-T Cells in Advanced Solid Tumors
Not yet reported Zhejiang University 36 participants Est. completion 2025-09 1 site Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Completed NCT NCT05987696
Natural Killer(NK) Cell Therapy in Acute Myeloid Leukemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 2 participants Est. completion 2025-01-17 1 site Stand-aloneOther conditions: AML, Adult, Minimal Residual DiseaseView official trial listing → -
Completed NCT NCT05993299
Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma
Not yet reported USWM, LLC (dba US WorldMeds) 7 participants Est. completion 2026-03-17 38 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Status unknown NCT NCT05998928
A Clinical Study to Evaluate the Safety and Efficacy of BCMA-GPRC5D CAR-T in Patients With Relapsed/Refractory Multiple Myeloma Who Received Three or More Lines of Therapy
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 10 participants Est. completion 2026-07-27 1 site Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT06001385
HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis
Not yet reported Center for International Blood and Marrow Transplant Research 313 participants Est. completion 2026-12-30 32 sites Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myeloid Leukemia, Chronic Lymphocytic Leukemia, Myeloproliferative Neoplasm, Lymphoma, Chronic Myelomonocytic Leukemia, Pro-Lymphocytic Leukemia, MyelofibrosisView official trial listing → -
Withdrawn NCT NCT06003179
Optimizing Lymphodepletion to Improve Outcomes in Patients Receiving Cell Therapy With Kymriah
Not yet reported University Health Network, Toronto Est. completion 2028-11 1 site Stand-aloneOther conditions: Lymphoma, Large B-Cell, DiffuseView official trial listing → -
Withdrawn NCT NCT06005649
Clinical Trial of HY004 Cell Injection in the Treatment of Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma
Not yet reported, Not yet reported Juventas Cell Therapy Ltd. Est. completion 2027-06 Stand-aloneOther conditions: Non-hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT06006390
CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors
Not yet reported, Not yet reported Chongqing Precision Biotech Co., Ltd 60 participants Est. completion 2026-08-31 3 sites Stand-aloneOther conditions: Gastric Cancer, Colon Cancer, Rectal Cancer, Esophageal Cancer, Pancreas Cancer, Lung Cancer, Breast CancerView official trial listing → -
Completed NCT NCT06006403
Safety and Efficacy of CD123-targeted CAR-NK for Relapsed/Refractory Acute Myeloid Leukemia or Blastic Plasmacytoid Dendritic Cell Neoplasm
Not yet reported, Not yet reported Chongqing Precision Biotech Co., Ltd 5 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN), Relapse Leukemia, Refractory LeukemiaView official trial listing → -
Withdrawn NCT NCT06009107
A Study of HY004 Treatment in Adult Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r B-ALL)
Not yet reported, Not yet reported Juventas Cell Therapy Ltd. Est. completion 2027-12-30 Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Status unknown NCT NCT06010875
A Clinical Research About CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors
Not yet reported Chongqing Precision Biotech Co., Ltd 48 participants Est. completion 2026-09-30 1 site Stand-aloneOther conditions: Renal Cell Carcinoma, Ovarian Cancer, Cervix Cancer, Metastatic Cancer, Advanced CancerView official trial listing → -
Status unknown NCT NCT06013111
An Exploratory Clinical Study Evaluating the Safety and Efficacy of Anti-CEA-CAR-T Cells Injection in Patients With CEA+ Locally Advanced and/or Metastatic Solid Tumors
Not yet reported China Medical University, China 9 participants Est. completion 2026-09-01 1 site Stand-aloneOther conditions: CarcinomaView official trial listing → -
Status unknown NCT NCT06027853
Natural Killer(NK) Cell Therapy Targeting CLL1 in Acute Myeloid Leukemia
Not yet reported Zhejiang University 24 participants Est. completion 2026-08-31 1 site Stand-aloneOther conditions: AML, AdultView official trial listing → -
Completed NCT NCT06027957
CD19 CAR T-Cell Therapy for R/R Non-Hodgkin Lymphoma and Acute Lymphoblastic Leukemia
Not yet reported Vinmec Research Institute of Stem Cell and Gene Technology 18 participants Est. completion 2025-07-31 1 site Stand-aloneOther conditions: B-Cell Non Hodgkin Lymphoma, B-Cell Acute Lymphoblastic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT06027983
Chimeric Receptor T Cells With Trastuzumab in HER2+ Advanced Breast Cancer and Other Solid Tumors
Not yet reported, Not yet reported National University Hospital, Singapore 36 participants Est. completion 2027-12-31 Stand-aloneOther conditions: HER2+ Advanced Breast Cancer, Other Solid TumorsView official trial listing → -
Active, not recruiting NCT NCT06034470
Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms
Not yet reported Fred Hutchinson Cancer Center 30 participants Est. completion 2029-05-31 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasm, Myeloproliferative NeoplasmView official trial listing → -
Status unknown NCT NCT06045585
JY231 Injection in the Treatment of Relapsed or Refractory B-cell Lymphoma
Not yet reported Guangdong Second Provincial General Hospital 20 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Relapsed or Refractory B-cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT06045806
A Study to Compare the Efficacy and Safety of Idecabtagene Vicleucel With Lenalidomide Maintenance Therapy Versus Lenalidomide Maintenance Therapy Alone in Adult Participants With Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Autologous Stem Cell Transplantation
Not yet reported Celgene 79 participants Est. completion 2029-11-20 101 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Terminated NCT NCT06048705
Study of GSK3901961 In Previously Treated Advanced (Metastatic OR Unresectable) Synovial Sarcoma/ Myxoid/Round Cell Liposarcoma, and Previously Treated Metastatic Non-Small Cell Lung Cancer
Not yet reported Adaptimmune 7 participants Est. completion 2023-06-08 21 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Status unknown NCT NCT06056752
QH103 Cell Injection for the Treatment of Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia
Not yet reported Anhui Provincial Hospital 10 participants Est. completion 2026-07-03 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT06079164
Study of KITE-197 in Participants With Relapsed or Refractory Large B-cell Lymphoma
Not yet reported Kite, A Gilead Company 21 participants Est. completion 2026-11 11 sites Stand-aloneOther conditions: Relapsed/Refractory Large B-cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT06084884
A Phase I/II Study to Evaluate AZD5851 in GPC3+ Advanced/Recurrent Hepatocellular Carcinoma
Not yet reported, Not yet reported AstraZeneca 94 participants Est. completion 2027-12-13 19 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT06093841
Relmacabtagene Autoleucel As Second-Line Therapy in Adult Patients with Aggressive B-cell NHL
Not yet reported Shanghai Ming Ju Biotechnology Co., Ltd. 46 participants Est. completion 2029-11-04 13 sites Stand-aloneOther conditions: Lymphoma, Large B-Cell, Diffuse, Follicular Lymphoma Grade 3B, High-grade B-cell Lymphoma, Mediastinal B-Cell Diffuse Large Cell LymphomaView official trial listing → -
Withdrawn NCT NCT06094842
Autologous T Cells Lentivirally Transduced to Express L1CAM-Specific Chimeric Antigen Receptors in Treating Patients With Locally Advanced and Unresectable or Metastatic Small Cell Neuroendocrine Prostate Cancer
Not yet reported Fred Hutchinson Cancer Center Est. completion 2028-03-15 1 site Stand-aloneOther conditions: Prostate Carcinoma, Prostate Small Cell Neuroendocrine Carcinoma, Stage III Prostate Cancer AJCC v8, Stage IV Prostate Cancer AJCC v8View official trial listing → -
Active, not recruiting NCT NCT06098326
CyFluATG in Lower Risk MDS
Not yet reported Asan Medical Center 30 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Myelodysplastic SyndromesView official trial listing → -
Status unknown NCT NCT06111625
Short-term Blinatumomab as a Bridge Therapy for Allo-HSCT in Low Burden B-ALL
Not yet reported Sichuan University 20 participants Est. completion 2026-08-31 1 site Stand-aloneOther conditions: Leukemia, LymphoidView official trial listing → -
Terminated NCT NCT06128044
CRISPR-Edited Allogeneic Anti-CLL-1 CAR-T Cell Therapy in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Not yet reported Caribou Biosciences, Inc. 12 participants Est. completion 2025-05-30 10 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia RefractoryView official trial listing → -
Status unknown NCT NCT06144385
A Phase 1, Single-arm, Open-label, Dose-escalation Study of JWATM204 as T Cell-targeted Immunotherapy in the Treatment Amongst Subjects With Advanced Hepatocellular Carcinoma
Not yet reported Shanghai Ming Ju Biotechnology Co., Ltd. 20 participants Est. completion 2024-12 1 site Stand-aloneOther conditions: Liver Carcinoma, Hepatic Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT06149403
A Study to Investigate the Efficacy and Safety of OTL-203 in Subjects With MPS-IH Compared With Standard of Care With Allogeneic HSCT
Not yet reported Orchard Therapeutics 41 participants Est. completion 2031-03 5 sites Stand-aloneOther conditions: MPS-IH (Hurler Syndrome)View official trial listing → -
Completed NCT NCT06150651
Safety of PiggyBac Transposon CAR T-cells Targeting CD-19 in Refractory Lupus.
Not yet reported Chulalongkorn University 3 participants Est. completion 2026-03-01 1 site Stand-aloneOther conditions: SLE (Systemic Lupus)View official trial listing → -
Completed NCT NCT06151847
Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma
Not yet reported University of Kansas Medical Center 11 participants Est. completion 2025-07-10 1 site Stand-aloneOther conditions: Clinical Stage IV Cutaneous Melanoma AJCC v8, Metastatic Melanoma, Pathologic Stage IIIC Cutaneous Melanoma AJCC v8, Unresectable MelanomaView official trial listing → -
Active, not recruiting NCT NCT06152172
CARTIMMUNE: Study of Patients With Autoimmune Diseases Receiving KYV-101
Not yet reported David Porter 24 participants Est. completion 2027-02 1 site Stand-aloneOther conditions: Idiopathic Inflammatory Myopathies, Diffuse Cutaneous Systemic Sclerosis, SLE Nephritis, ANCA Associated VasculitisView official trial listing → -
Status unknown NCT NCT06160362
The Safety and Efficacy of Double-target CART-19 and 20 Cells in Non-Hodgkin's Lymphoma (NHL)
Not yet reported Henan Cancer Hospital 20 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: Non-hodgkin Lymphoma,B CellView official trial listing → -
Not yet recruiting NCT NCT06175702
Treatment Protocol for Newky Diagnosed Adult Ph Positive ALL
PETHEMA Foundation 150 participants Est. completion 2030-12-25Other conditions: Lymphoblastic Leukemia, Philadelphia-Positive ALL, Adult ALLView official trial listing → -
Status unknown NCT NCT06182735
CD70-targeted CAR-NKT Cells(CGC729) Therapy in the Renal Cell Carcinoma
Not yet reported Fudan University 9 participants Est. completion 2025-01-28 1 site Stand-aloneOther conditions: Renal Cell CarcinomaView official trial listing → -
Withdrawn NCT NCT06190249
Efficacy & Safety for LN144 With Pembrolizumab With High Risk Stage IIIb-dResectable Melanoma
Not yet reported James Isaacs, MD Est. completion 2028-07 Stand-aloneOther conditions: Stage IIIB Melanoma, Stage IIIC Melanoma, Stage IIID MelanomaView official trial listing → -
Not yet recruiting NCT NCT06196658
Early Phase I Study of Autologous T Cells (EX02 CAR-T) for Unresectable Pancreatic/Bile Duct Cancer
Not yet reported Zhang Xiaofeng,MD 6 participants Est. completion 2027-12-31 Stand-aloneOther conditions: Pancreatic Cancer, Advanced Biliary CancerView official trial listing → -
Terminated NCT NCT06197178
A Study of LCAR-G08 in Subjects With Advanced Gastrointestinal Tumors Expressing Guanylyl Cyclase C (GCC)
Not yet reported Peking University 17 participants Est. completion 2025-10-22 2 sites Stand-aloneOther conditions: Advanced Gastrointestinal TumorsView official trial listing → -
Withdrawn NCT NCT06205290
A Study to Compare the Efficacy and Safety of Lisocabtagene Maraleucel vs Investigator's Choice Options in Adult Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, Whose Disease Has Failed Treatment With Both BTKi and BCL2i Therapies
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company Est. completion 2031-10-13 48 sites Stand-aloneOther conditions: Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Status unknown NCT NCT06206902
F01 in the Treatment of Relapsed/Refractory Non-hodgkin's Lymphoma
Not yet reported Shanghai Simnova Biotechnology Co.,Ltd. 55 participants Est. completion 2025-12 2 sites Stand-aloneOther conditions: Non-Hodgkin's LymphomaView official trial listing → -
Status unknown NCT NCT06208280
F01 in the Treatment of Autoimmune Diseases
Not yet reported RenJi Hospital 20 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Status unknown NCT NCT06209671
INS19 CAR-T Cells for the Treatment of Relapsed or Refractory Acute B Lymphoblastic Leukemia
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 12 participants Est. completion 2026-01-15 Stand-aloneOther conditions: Leukemia, B-cellView official trial listing → -
Active, not recruiting NCT NCT06220097
Mitoxantrone Hydrochloride Liposome Injection-containing Bridging Regimen and CD19-targeting CAR-T Therapies
Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 28 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: B-cell Acute Lymphoblastic Leukemia, B-cell Lymphoma RefractoryView official trial listing → -
Active, not recruiting NCT NCT06220201
A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 120 participants Est. completion 2027-07-15 34 sites Stand-aloneOther conditions: Multiple Sclerosis, Myasthenia GravisView official trial listing → -
Status unknown NCT NCT06224049
Treatment of Relapsed or Refractory Epstein-Barr Virus Positive T-cell Lymphoma With hNeo-T
Not yet reported BGI, China 6 participants Est. completion 2026-06-30 1 site Stand-aloneOther conditions: T-cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT06228404
Clinical Study of Safety and Efficacy of Enhanced PSMA CAR- T in Refractory CRPC
Not yet reported Shanghai Changzheng Hospital 18 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Metastatic Castration-resistant Prostate Cancer, Castration-resistant Prostate CancerView official trial listing → -
Not yet recruiting NCT NCT06228781
Autologous Hematopoietic Stem Cell Transplantation for Refractory Multiple Sclerosis
Not yet reported Tianjin Medical University General Hospital 20 participants Est. completion 2029-01-01 Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Completed NCT NCT06236425
TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 7 participants Est. completion 2025-04-09 1 site Stand-aloneOther conditions: Squamous Cell Carcinoma of Head and Neck, Metastatic Squamous Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT06237881
A Phase 1/2 Study of KSQ-001EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate the SOCS1 Gene, in Patients With Select Advanced Solid Tumors
Not yet reported, Not yet reported M.D. Anderson Cancer Center 15 participants Est. completion 2029-01-01 1 site Stand-aloneOther conditions: Advanced Solid Tumor, Melanoma, Lung Neoplasms, Head and Neck NeoplasmsView official trial listing → -
Status unknown NCT NCT06242249
Anti-BCMA CAR-NK Therapy in Relapsed or Refractory Multiple Myeloma
Not yet reported, Not yet reported Shahid Beheshti University of Medical Sciences 10 participants Est. completion 2026-06-30 1 site Stand-aloneOther conditions: Multiple Myeloma, RefractoryView official trial listing → -
Not yet recruiting NCT NCT06243159
JY231(Internal Clinical Drug Code) Injection for the Treatment of Refractory Autoimmune Diseases
Not yet reported Shanxi Bethune Hospital 20 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Status unknown NCT NCT06247917
Evaluate the Efficacy and Safety of Allogeneic Haematopoietic Stem Cell Transplantation With FBM Conditioning for MDS
Not yet reported Ruijin Hospital 59 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Myelodysplastic Syndrome With Excess Blasts-1, Myelodysplastic Syndrome With Excess Blasts-2, Myelodysplastic SyndromesView official trial listing → -
Active, not recruiting NCT NCT06253520
Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer
Not yet reported National Cancer Institute (NCI) 210 participants Est. completion 2029-02-20 1 site Stand-aloneOther conditions: Metastatic Solid Cancers, Colorectal Cancer, Breast Cancer, Non-Small Cell Lung Cancer, Gastrointestinal Cancer, Ovarian Cancer, Genitourinary CancerView official trial listing → -
Active, not recruiting NCT NCT06253663
Study of KTE-X19 in Adult Japanese Participants With Relapsed/Refractory Mantle Cell Lymphoma or Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Not yet reported Kite, A Gilead Company 25 participants Est. completion 2027-07 9 sites Stand-aloneOther conditions: Relapsed/Refractory Mantle Cell Lymphoma, Relapsed/Refractory B-precursor Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT06265220
AB-101 in Combination With B-Cell Depleting mAb in Patients Who Failed Treatment for Class III or IV Lupus Nephritis or Other Forms of Refractory Systemic Lupus Erythematosus
Not yet reported Artiva Biotherapeutics, Inc. 51 participants Est. completion 2027-08 9 sites Stand-aloneOther conditions: Lupus Nephritis - WHO Class III, Lupus Nephritis - WHO Class IV, Refractory Systemic Lupus Erythematosus, SLEView official trial listing → -
Status unknown NCT NCT06277011
Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research
Not yet reported Anhui Provincial Hospital 18 participants Est. completion 2025-05-15 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Non-hodgkin LymphomaView official trial listing → -
Not yet recruiting NCT NCT06277804
A Phase I Study of LTC004 Combin With FC in Patients With Advanced/Metastatic Malignancies Tumor
Not yet reported Letolab 48 participants Est. completion 2027-07-01 Stand-aloneOther conditions: Adult Solid TumorView official trial listing → -
Active, not recruiting NCT NCT06285422
Study Evaluating SC262 in Subjects With r/r Non-Hodgkin's Lymphoma (VIVID)
Not yet reported Sana Biotechnology 6 participants Est. completion 2029-03 3 sites Stand-aloneOther conditions: Non Hodgkin's Lymphoma, Large B-cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT06294236
Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM)
Not yet reported Sana Biotechnology 7 participants Est. completion 2028-03 5 sitesOther conditions: Lupus Erythematosus, Systemic Lupus Erythematosus, SLE (Systemic Lupus), Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Granulomatous Polyangiitis, Microscopic PolyangiitisView official trial listing → -
Terminated NCT NCT06295549
Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported The First Affiliated Hospital with Nanjing Medical University 11 participants Est. completion 2025-08-22 3 sites Stand-aloneOther conditions: Relapsed and Refractory B-cell Non-Hodgkin LymphomaView official trial listing → -
Not yet recruiting NCT NCT06297772
Compare the Efficacy and Safety of Dec-FB4 and FB4 as Conditioning Regimen for AML-MR
Not yet reported Ruijin Hospital 220 participants Est. completion 2028-05-01 1 site Stand-aloneOther conditions: AML, AdultView official trial listing → -
Not yet recruiting NCT NCT06298266
To Assess Safety, Tolerability, and Efficacy of Anti-GPRC5D-CD19-CAR-T in Relapsed/Refractory Multiple Myeloma
Not yet reported Guangdong Second Provincial General Hospital 15 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Relapsed or Refractory Multiple MyelomaView official trial listing → -
Withdrawn NCT NCT06313996
A Study to Evaluate the Efficacy and Safety of Liso-cel Compared to Standard of Care in Adults With Relapsed or Refractory Follicular Lymphoma
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company Est. completion 2031-10-16 Stand-aloneOther conditions: Relapsed or Refractory Follicular LymphomaView official trial listing → -
Not yet recruiting NCT NCT06314828
A Tolerability, Safety and Efficacy Study of RJMty19 in Subjects With Relapsed or Refractory B-NHL
Not yet reported Guangdong Ruishun Biotech Co., Ltd 30 participants Est. completion 2027-05-20 Stand-aloneOther conditions: B-cell Non-Hodgkin's LymphomaView official trial listing → -
Status unknown NCT NCT06316076
Safety and Efficacy Study of CD19-CAR-DNT Cells in Autoimmune Diseases
Not yet reported RenJi Hospital 48 participants Est. completion 2026-06 1 site Stand-aloneOther conditions: Systemic Lupus Erythematosus, Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis, Idiopathic Inflammatory Myopathies, Systemic SclerosisView official trial listing → -
Active, not recruiting NCT NCT06325748
SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS
Not yet reported Senti Biosciences 21 participants Est. completion 2040-08 8 sites Stand-aloneOther conditions: AML/MDS, CD33 Expressing Hematological Malignancies, FLT3 Expressing Hematological MalignanciesView official trial listing → -
Active, not recruiting NCT NCT06333483
Obe-cel in Adolescent [Applicable in UK Only] and Adult Severe, Refractory Systemic Lupus Erythematosus
Not yet reported Autolus Limited 16 participants Est. completion 2027-09 6 sites Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Not yet recruiting NCT NCT06340490
A Study of RJMty19 in Refractory Systemic Lupus Erythematosus (SLE)
Not yet reported Guangdong Ruishun Biotech Co., Ltd 24 participants Est. completion 2027-12-31 4 sites Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Withdrawn NCT NCT06341647
Phase 1 Clinical Trial to Evaluate the Safety and Anti-Tumor Activity of AB-201
Not yet reported GC Cell Corporation Est. completion 2029-02 Stand-aloneOther conditions: Breast Cancer, Gastric Cancer, Gastroesophageal Junction AdenocarcinomaView official trial listing → -
Terminated NCT NCT06342960
KYSA-3: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis
Not yet reported, Not yet reported Kyverna Therapeutics 2 participants Est. completion 2025-12-22 6 sitesOther conditions: Lupus Nephritis, Lupus Nephritis - WHO Class III, Lupus Nephritis - WHO Class IVView official trial listing → -
Active, not recruiting NCT NCT06342986
Intraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Not yet reported Masonic Cancer Center, University of Minnesota 3 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Gynecologic Cancer, Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cavity CancerView official trial listing → -
Terminated NCT NCT06343376
Genetically Engineered Cells (EGFRt/19-28z/IL-12 CAR T Cells) for the Treatment of Relapsed or Refractory CD19+ Hematologic Malignancies
Not yet reported Roswell Park Cancer Institute 1 participants Est. completion 2025-01-03 1 site Stand-aloneOther conditions: Recurrent Chronic Lymphocytic Leukemia, Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Follicular Lymphoma, Recurrent High Grade B-Cell Lymphoma, Recurrent Mantle Cell Lymphoma, Recurrent Transformed Chronic Lymphocytic Leukemia, Recurrent Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma, Refractory Chronic Lymphocytic Leukemia, Refractory Diffuse Large B-Cell Lymphoma, Refractory Follicular Lymphoma, Refractory High Grade B-Cell Lymphoma, Refractory Mantle Cell Lymphoma, Refractory Transformed Chronic Lymphocytic Leukemia, Refractory Transformed Follicular Lymphoma to Diffuse Large B-Cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT06358053
CRTE7A2-01 TCR-T Cells for HPV-16 Positive Advanced Cancers
Not yet reported Corregene Biotechnology Co., Ltd 24 participants Est. completion 2028-04-30 Stand-aloneOther conditions: Cervical Cancer, Anal Cancer, Head and Neck Cancers, Other Solid TumorsView official trial listing → -
Active, not recruiting NCT NCT06358430
Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)
Not yet reported M.D. Anderson Cancer Center 10 participants Est. completion 2029-01-18 1 site Stand-aloneOther conditions: Colorectal Cancer, Minimal Residual DiseaseView official trial listing → -
Status unknown NCT NCT06367114
Clinical Trial of ssCART-19 Cell Injection in the Treatment of Relapsed or Refractory Acute Lymphoblastic Leukemia (Including Central Nervous System Infiltration)
Not yet reported Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd 50 participants Est. completion 2025-12 2 sites Stand-aloneOther conditions: Relapsed or Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Enrolling by invitation NCT NCT06375993
A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease
Not yet reported Adicet Therapeutics 180 participants Est. completion 2027-12 2 sites Stand-aloneOther conditions: Lupus Nephritis, Autoimmune Diseases, Systemic Sclerosis (SSc), Systemic Lupus Erythematosus (SLE), ANCA-Associated Vasculitis (AAV), Idiopathic Inflammatory Myopathies, Stiff Person SyndromeView official trial listing → -
Withdrawn NCT NCT06377228
A Study of TAK-007 in Adults With Refractory Lupus Nephritis (LN) or Refractory Systemic Sclerosis (SSc)
Not yet reported Takeda Est. completion 2030-09-02 1 site Stand-aloneOther conditions: Refractory Lupus Nephritis, Refractory Systemic SclerosisView official trial listing → -
Not yet recruiting NCT NCT06383507
A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors
Not yet reported Zhejiang University 18 participants Est. completion 2029-04-21 Stand-aloneOther conditions: Metastatic Tumor, Advanced Solid Tumor, Renal Cell Carcinoma, Ovarian Cancer, Cervix Cancer, Head and Neck Squamous Cell Carcinoma, Nasopharyngeal CarcinomaView official trial listing → -
Not yet recruiting NCT NCT06385808
Efficacy and Safety of MTBF Conditioning Regimen for Salvageable Allo-HSCT in the Treatment of R/R AML
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 37 participants Est. completion 2026-12-31 Stand-aloneOther conditions: Relapse Leukemia, Refractory Acute Myeloid Leukemia, Conditioning, Hematopoietic Stem Cell TransplantationView official trial listing → -
Status unknown NCT NCT06393335
Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research
Not yet reported The Children's Hospital of Zhejiang University School of Medicine 36 participants Est. completion 2026-03-15 1 site Stand-aloneOther conditions: Acute Lymphoblastic Leukemia, Non-hodgkin LymphomaView official trial listing → -
Status unknown NCT NCT06394622
A Clinical Research About CD70-targeted CAR-NKT Cells Therapy Advanced Malignant Solid Tumors
Not yet reported Fudan University 12 participants Est. completion 2026-06-28 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Terminated NCT NCT06400303
KYSA-5: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis
Not yet reported, Not yet reported Kyverna Therapeutics 3 participants Est. completion 2026-06-16 2 sitesOther conditions: Systemic Sclerosis, Systemic Sclerosis - Diffuse Cutaneous, Systemic Sclerosis - 2013 ACR/EULAR Classification CriteriaView official trial listing → -
Status unknown NCT NCT06412458
IM83 Clinical Study of CAR-T Cell Therapy in Patients With Relapsed or Refractory Osteosarcoma
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 9 participants Est. completion 2026-06-15 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Active, not recruiting NCT NCT06413498
A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma
Not yet reported Kite, A Gilead Company 452 participants Est. completion 2031-07 117 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Status unknown NCT NCT06421701
Anti-CD19 CAR-NK Cells in Refractory/Relapsed Systemic Lupus Erythematosus
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 10 participants Est. completion 2026-05-31 1 site Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Suspended NCT NCT06447987
Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic Leukemia
Not yet reported City of Hope Medical Center 24 participants Est. completion 2026-12-05 1 site Stand-aloneOther conditions: Recurrent Acute Lymphoblastic Leukemia, Refractory Acute Lymphoblastic LeukemiaView official trial listing → -
Active, not recruiting NCT NCT06451159
A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis
Not yet reported Bruce Cree 10 participants Est. completion 2027-02 1 site Stand-aloneOther conditions: Progressive Multiple SclerosisView official trial listing → -
Terminated NCT NCT06462144
IMPT-514 in Systemic Lupus Erythematosus, Anca-associated Vasculitis, and Idiopathic Inflammatory Myopathy
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 3 participants Est. completion 2025-10-21 3 sites Stand-aloneOther conditions: Systemic Lupus Erythematosus (SLE), ANCA Associated Vasculitis (AAV), Idiopathic Inflammatory Myopathy (IIM)View official trial listing → -
Active, not recruiting NCT NCT06464185
A Prospective Clinical Study of CD3-CD20 Bisspecific Antibody Based Therapy Combined With CD19-CAR T Cells in the Treatment of Relapsed Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 53 participants Est. completion 2027-04-30 1 site Stand-aloneOther conditions: B-cell Non-Hodgkin LymphomaView official trial listing → -
Completed NCT NCT06464965
Clinical Study of Cord Blood-Derived CAR-NK Cells in Gastric Cancer and Pancreatic Cancer
Not yet reported Zhejiang Provincial People's Hospital 9 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: Gastric Cancer, Pancreas AdenocarcinomaView official trial listing → -
Status unknown NCT NCT06468267
RIC With Thiotepa Combined With Bu/Flu/Ara-C in Allo-HSCT for Relapsed or Refractory PTCL.
Not yet reported Xianmin Song, MD 50 participants Est. completion 2026-07-15 1 site Stand-aloneOther conditions: Peripheral T Cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT06472479
LCAR-M61S and LCAR-M61D in Treatment of Relapsed/Refractory Multiple Myeloma
Not yet reported The First Affiliated Hospital with Nanjing Medical University 66 participants Est. completion 2029-10-12 4 sites Stand-aloneOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT06480565
A Phase 1/2 Trial of ADI-270 in ccRCC
Not yet reported, Not yet reported Adicet Therapeutics 60 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Clear Cell Renal Cell CarcinomaView official trial listing → -
Not yet recruiting NCT NCT06505551
Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma
Not yet reported, Not yet reported SCG Cell Therapy Pte. Ltd. 66 participants Est. completion 2028-12 Stand-aloneOther conditions: HPV-Related Squamous Cell Carcinoma, HPV-Related Cervical Squamous Cell Carcinoma, HPV-Related Vulvar Squamous Cell Carcinoma, HPV-Related Penile Squamous Cell Carcinoma, HPV-Related Vaginal Squamous Cell Carcinoma, HPV-Related Anal Squamous Cell Carcinoma, HPV-Related Head and Neck CancerView official trial listing → -
Status unknown NCT NCT06532630
Anti-CD19-CAR-T Cells in Subjects With Relapsed/Refractory B Cell Malignancies
Not yet reported Shanghai First Song Biotechnology Co., LTD 9 participants Est. completion 2026-09-01 1 site Stand-aloneOther conditions: B-Cell MalignancyView official trial listing → -
Status unknown NCT NCT06532643
Safety and Efficacy of Anti-CD20/CD30 CAR-T Cells in Subjects with Relapsed/Refractory Lymphoma
Not yet reported Shanghai First Song Biotechnology Co., LTD 9 participants Est. completion 2026-09-01 1 site Stand-aloneOther conditions: Relapsed/Refractory LymphomaView official trial listing → -
Not yet recruiting NCT NCT06545201
RE001 T Cell Injection for the Treatment of KRAS G12V Mutated Solid Tumors
Not yet reported Henan Cancer Hospital 30 participants Est. completion 2027-04-01 1 site Stand-aloneOther conditions: KRAS G12V, T Cell TherapyView official trial listing → -
Suspended NCT NCT06549296
Clinical Study on Targeted CD19CAR-T Therapy for Autoimmune Diseases
Not yet reported Nanjing Bioheng Biotech Co., Ltd. 12 participants Est. completion 2027-08-01 1 site Stand-aloneOther conditions: Systemic Lupus Erythematosus, Systemic Sclerosis, ANCA Associated Vasculitis, Idiopathic Inflammatory Myopathies, Sjogren's Syndrome, Autoimmune DiseasesView official trial listing → -
Completed NCT NCT06556108
ALPP CAR-T Cells for ALPP-Positive Advanced Solid Tumors
Not yet reported, Not yet reported Xinqiao Hospital of Chongqing 5 participants Est. completion 2025-07-30 1 site Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Withdrawn NCT NCT06572631
Multi-antigen Specific CD8+ T Cells With Decitabine and Lymphodepleting Chemotherapy for the Treatment of Patients With Relapsed or Refractory AML or MDS Following an Allogeneic Hematopoietic Cell Transplantation From a Matched Donor
Not yet reported City of Hope Medical Center Est. completion 2026-12-12 Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia, Refractory Myelodysplastic SyndromeView official trial listing → -
Active, not recruiting NCT NCT06577025
A Study of Different Sequences of Cilta-cel, Talquetamab in Combination With Daratumumab and Teclistamab in Combination With Daratumumab Following Induction With Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in Participants With Standard-risk Newly Diagnosed Multiple Myeloma
Not yet reported Janssen Research & Development, LLC 43 participants Est. completion 2030-09-30 16 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT06588491
KYSA-8: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Treatment Refractory Stiff Person Syndrome
Not yet reported Kyverna Therapeutics 27 participants Est. completion 2026-06-25 3 sitesOther conditions: Stiff-Person Syndrome, SPSView official trial listing → -
Not yet recruiting NCT NCT06602323
TMLI/Fludarabine/Melphalan Conditioning for Allogeneic Transplantation in High-risk Myelodysplastic Syndrome or Acute Myeloid Leukemia.
Not yet reported Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 34 participants Est. completion 2028-10-01Other conditions: Myelodysplastic Syndromes, Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT06613035
Twice-per-weekSelinexor, 2 Days Melphalan
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 126 participants Est. completion 2027-09-30 4 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Withdrawn NCT NCT06626256
STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma
Not yet reported City of Hope Medical Center Est. completion 2027-10-30 Stand-aloneOther conditions: Locally Advanced Cervical Carcinoma, Locally Advanced Colorectal Carcinoma, Locally Advanced Malignant Solid Neoplasm, Locally Advanced Melanoma, Locally Advanced Pancreatic Ductal Adenocarcinoma, Locally Advanced Renal Cell Carcinoma, Metastatic Cervical Carcinoma, Metastatic Colorectal Carcinoma, Metastatic Malignant Solid Neoplasm, Metastatic Melanoma, Metastatic Pancreatic Ductal Adenocarcinoma, Metastatic Renal Cell Carcinoma, Stage II Pancreatic Cancer AJCC v8, Stage III Cervical Cancer AJCC v8, Stage III Colorectal Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8, Stage III Renal Cell Cancer AJCC v8, Stage IV Cervical Cancer AJCC v8, Stage IV Colorectal Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Unresectable Cervical Carcinoma, Unresectable Colorectal Carcinoma, Unresectable Malignant Solid Neoplasm, Unresectable Melanoma, Unresectable Pancreatic Ductal Adenocarcinoma, Unresectable Renal Cell CarcinomaView official trial listing → -
Not yet recruiting NCT NCT06631040
Cell Therapy with Anti-CD19 CAR-NK Cells in Patients with Relapsed or Resistant B-ALL
Not yet reported, Not yet reported Shahid Beheshti University of Medical Sciences 10 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: Acute Lymphocytic Leukemia in RelapseView official trial listing → -
Not yet recruiting NCT NCT06641453
CAR-T Cell Therapy Targeting GPC3 in Patients with Advanced GPC3-Positive Hepatocellular Carcinoma
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2028-11-15 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Suspended NCT NCT06653023
Universal CAR-T Cells (REVO-UWD-03) for Advanced Hepatocellular Carcinoma and Lung Cancer
Not yet reported Wondercel Biotech (ShenZhen) 60 participants Est. completion 2027-12-30 1 site Stand-aloneOther conditions: HCC - Hepatocellular Carcinoma, NSCLC (Advanced Non-small Cell Lung Cancer)View official trial listing → -
Active, not recruiting NCT NCT06655896
Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic Sclerosis
Not yet reported Novartis Pharmaceuticals 96 participants Est. completion 2032-08-30 93 sites Stand-aloneOther conditions: Scleroderma, DiffuseView official trial listing → -
Suspended NCT NCT06662227
Universal CAR-T Cells (REVO-UWD-19) for Refractory and Relapsed B-Cell Tumors
Not yet reported Wondercel Biotech (ShenZhen) 30 participants Est. completion 2029-12-30 1 site Stand-aloneOther conditions: B Cell Lymphoma, B Cell Leukemia, B Cell MalignancyView official trial listing → -
Suspended NCT NCT06663046
Universal CAR-T Cells (REVO-UWD-00B) for Refractory and Relapsed Multiple Myeloma
Not yet reported Wondercel Biotech (ShenZhen) 30 participants Est. completion 2029-12-30 1 site Stand-aloneOther conditions: Multiple Myleoma, Refractory and Relapsed Multiple MyelomaView official trial listing → -
Active, not recruiting NCT NCT06665256
Phase 2 Study of Rapcabtagene Autoleucel in Myositis
Not yet reported Novartis Pharmaceuticals 21 participants Est. completion 2032-11-29 68 sites Stand-aloneOther conditions: Idiopathic Inflammatory MyopathiesView official trial listing → -
Not yet recruiting NCT NCT06667973
Efficacy of Gilteritinib in Combination With FLAI as Induction Therapy of FLT3-positive Acute Myeloid Leukemia
Not yet reported Gruppo Italiano Malattie EMatologiche dell'Adulto 80 participants Est. completion 2030-06 Stand-aloneOther conditions: Acute Myeloid Leukemia, FLT3 Gene Mutation, Adult AML, DiagnosisView official trial listing → -
Suspended NCT NCT06677710
IDP-023 g-NK Cells Plus Ocrelizumab in Patients With Progressive Multiple Sclerosis
Not yet reported Indapta Therapeutics, INC. 34 participants Est. completion 2028-12-31 5 sites Stand-aloneOther conditions: Multiple Sclerosis, Primary Progressive Multiple Sclerosis (PPMS), Secondary Progressive Multiple Sclerosis (SPMS), Non-Active Secondary Progressive Multiple Sclerosis, Non-Active SPMS, Autoimmune Diseases of the Nervous System, Nervous System Diseases, Autoimmune Diseases, Demyelinating Diseases, Immune System Diseases, Demyelinating Autoimmune Diseases, Central Nervous System (CNS)View official trial listing → -
Suspended NCT NCT06680661
ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis
Not yet reported Leland Metheny 20 participants Est. completion 2028-10-31 1 site Stand-aloneOther conditions: Acute Myelogenous Leukemia, Acute Lymphatic Leukemia, Chronic Myelogenous Leukemia, Myelodysplastic Syndromes, Myelodysplastic Syndrome Other, Chronic Myelomonocytic Leukemia, Lymphoma, Hodgkin LymphomaView official trial listing → -
Withdrawn NCT NCT06690281
A Phase II Study of Adjuvant Immunotherapy Targeting KRAS G12D, KRAS G12V, or TP53 R175H for Participants With Advanced Gastrointestinal Malignancies
Not yet reported National Cancer Institute (NCI) Est. completion 2025-09-09 1 site Stand-aloneOther conditions: Gastrointestinal Carcinoma, Pancreatic Cancer, Hepatocellular Cancer, Cholangiocarcinoma, Duodenal Cancer, Colorectal Cancer, Small Bowel Cancer, Metastatic CancersView official trial listing → -
Withdrawn NCT NCT06698744
UF-KURE-BCMA CAR-T Cells in Patients With Relapsed or Refractory Multiple Myeloma
Not yet reported David Wald Est. completion 2028-09 1 site Stand-aloneOther conditions: Multiple Myeloma, Multiple Myeloma in Relapse, Multiple Myeloma, RefractoryView official trial listing → -
Completed NCT NCT06703346
Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Not yet reported USWM CT, LLC 82 participants Est. completion 2026-07-24 38 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Not yet recruiting NCT NCT06741813
Allo-HSCT vs ASCT in Adult T-LBL
Not yet reported Peking University People's Hospital 230 participants Est. completion 2029-12-31 Stand-aloneOther conditions: T Lymphoblastic LymphomaView official trial listing → -
Not yet recruiting NCT NCT06748872
EPITOME-1015-I: a Study to Investigate the Safety and Tolerability of MDG1015 in Patients with Epithelial Ovarian Cancer, Gastroesophageal Adenocarcinoma, Round Cell Liposarcoma And/or Synovial Sarcoma
Not yet reported Medigene AG 55 participants Est. completion 2042-08-01 1 site Stand-aloneObstructive sleep apnea Other conditions: Epithelial Ovarian Cancer, Gastro-esophageal Junction Cancer, Soft Tissue Sarcoma (STS), Synovial SarcomaView official trial listing → -
Active, not recruiting NCT NCT06752694
Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemia
Not yet reported Fred Hutchinson Cancer Center 1 participants Est. completion 2026-10-15 1 site Stand-aloneOther conditions: Aplastic AnemiaView official trial listing → -
Withdrawn NCT NCT06752876
CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy, in Patients With Refractory Systemic Lupus Erythematosus (GALLOP)
Not yet reported Caribou Biosciences, Inc. Est. completion 2029-04 Stand-aloneOther conditions: Systemic Lupus Erythematosus, Lupus, Lupus Erythematosus, Lupus NephritisView official trial listing → -
Not yet recruiting NCT NCT06825455
Allogeneic B7H3 CAR-γδT Cell Therapy for Advanced Solid Tumors
Not yet reported Peking University 18 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Advanced Solid Tumors, Ovarian Cancers, Peritoneal (metastatic) CancerView official trial listing → -
Completed NCT NCT06837987
Modified Transplantation Regimen and aGVHD Prophylaxis for Severe Aplastic Anemia in the Setting of Allogeneic HSCT.
Hematology department of the 920th hospital 72 participants Est. completion 2025-08-01 1 siteOther conditions: Aplastic Anaemia, Transplantation ConditioningView official trial listing → -
Not yet recruiting NCT NCT06852573
Clinical Study of ZM001 Injection in the Treatment of Refractory Systemic Lupus Erythematosus
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 18 participants Est. completion 2027-08-20 Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Not yet recruiting NCT NCT06879262
Clinical Study of Novel TLR2-Containing CAR-T Cells Targeting CD19 and CD22 for Relapsed/Refractory B-ALL and NHL
Not yet reported Tongji Hospital 60 participants Est. completion 2029-02-28 Stand-aloneOther conditions: R/R NHLView official trial listing → -
Not yet recruiting NCT NCT06888752
LCAR-M61SQ in Treatment of Relapsed/Refractory Multiple Myeloma
Not yet reported First Affiliated Hospital of Wenzhou Medical University 35 participants Est. completion 2030-12-30 Stand-aloneOther conditions: Relapsed/Refractory Multiple MyelomaView official trial listing → -
Not yet recruiting NCT NCT06900192
A Study of Allogeneic Hematopoietic Cell Transplantation for Primary Progressive Multiple Sclerosis
Not yet reported Stanford University 10 participants Est. completion 2029-08 Stand-aloneOther conditions: Primary Progressive Multiple Sclerosis, Multiple Sclerosis, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary ProgressiveView official trial listing → -
Terminated NCT NCT06912529
Axicabtagene Ciloleucel CAR T-cells in Patients With Relapsed or Refractory Primary Mediastinal B-cell Lymphoma
Not yet reported Universität Münster 1 participants Est. completion 2025-07-25 1 site Stand-aloneOther conditions: B-cell Lymphoma Refractory, B-cell Lymphoma RecurrentView official trial listing → -
Withdrawn NCT NCT06926985
An Exploratory Clinical Study of Anti-CD19/BCMA Chimeric Antigen Receptor NK Cell Injection in the Treatment of IgA Nephropathy
Not yet reported Jieyang People's Hospital Est. completion 2027-04-30 1 site Stand-aloneOther conditions: IgA Nephropathy (IgAN)View official trial listing → -
Not yet recruiting NCT NCT06935136
Study to Evaluate the Efficacy and Safety of Axicabtagene Ciloleucel Injection as First-Line Therapy of High-Risk Large B-Cell Lymphoma
Not yet reported Ruijin Hospital 60 participants Est. completion 2028-04-09 1 site Stand-aloneOther conditions: CAR-T Cell Therapy, High-risk Large B-cell Lymphoma (LBCL)View official trial listing → -
Not yet recruiting NCT NCT06939270
CD73/AXL Targeted HypoSti.CAR-T Cells in CD73/AXL Positive Advanced/Metastatic Solid Tumors
Not yet reported, Not yet reported Chinese PLA General Hospital 30 participants Est. completion 2028-05-01 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Not yet recruiting NCT NCT06954987
Venetoclax or Placebo in Combination With Reduced-Intensity Conditioning Hematopoietic Cell (Bone Marrow/Blood Stem Cell) Transplant and as Maintenance Therapy After Transplant in Patients With Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
Not yet reported National Cancer Institute (NCI) 244 participants Est. completion 2028-05-15 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Active, not recruiting NCT NCT06961786
TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 With Lymphocyte-depleting Chemotherapy and TILs in the Treatment of Melanoma
Not yet reported TILT Biotherapeutics Ltd. 9 participants Est. completion 2027-04 1 site Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Suspended NCT NCT06968195
Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma
Not yet reported Roswell Park Cancer Institute 24 participants Est. completion 2029-05-30 1 site Stand-aloneOther conditions: Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma, Recurrent Hepatocellular Carcinoma, Refractory Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8View official trial listing → -
Active, not recruiting NCT NCT06973096
CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy
Not yet reported University of Pennsylvania 9 participants Est. completion 2042-07 1 site Stand-aloneOther conditions: GlioblastomaView official trial listing → -
Withdrawn NCT NCT06984341
A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Pharmacodynamics, and Efficacy of P-CD19CD20-ALLO1 in Participants With Severe, Treatment-refractory Systemic Lupus Erythematosus (SLE)
Not yet reported Genentech, Inc. Est. completion 2033-11-01 2 sites Stand-aloneOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Not yet recruiting NCT NCT06986018
Clinical Study on the Targeted CD19 Universal CAR-T Cell Injection (RD06-04) for the Treatment of IIM and AAV
Not yet reported Peking University People's Hospital 12 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Idiopathic Inflammatory Myopathies, ANCA-Associated VasculitisView official trial listing → -
Not yet recruiting NCT NCT06986434
CAR19BCMA CAR-T Cells for the Treatment of R/R Plasma Cell Neoplasms and Lymphomas/Leukemias With Plasmacytic Differentiation
Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 20 participants Est. completion 2028-08-25 1 site Stand-aloneOther conditions: Relapsed or Refractory Plasma Cell Neoplasms, Lymphomas/Leukemias With Plasmacytic DifferentiationView official trial listing → -
Not yet recruiting NCT NCT06988085
Impact of Lymphodepletion Regimen on the Response to CAR T-cells in Patients With With Relapsed/Refractory Large B-cell Lymphoma
Assistance Publique - Hôpitaux de Paris 42 participants Est. completion 2027-05-30Other conditions: Large B Cell Lymphoma, CAR T CellView official trial listing → -
Withdrawn NCT NCT07006805
RESET-MS: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Multiple Sclerosis
Not yet reported, Not yet reported Cabaletta Bio Est. completion 2029-10 Stand-aloneOther conditions: Relapsing Multiple Sclerosis (RMS), Progressive Multiple Sclerosis (PMS), Multiple Sclerosis - Relapsing Remitting, Multiple Sclerosis, Multiple Sclerosis (Relapsing Remitting), Multiple Sclerosis (MS) - Relapsing-remitting, Progressive Multiple SclerosisView official trial listing → -
Active, not recruiting NCT NCT07008378
A Study to Evaluate the Safety, Tolerability, Cellular Kinetics, and Pharmacodynamics of P-CD19CD20-ALLO1 in Participants With Multiple Sclerosis
Not yet reported Genentech, Inc. 60 participants Est. completion 2032-08-31 5 sites Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Active, not recruiting NCT NCT07015983
A Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 89 participants Est. completion 2032-06-15 97 sites Stand-aloneOther conditions: Lupus Erythematosus, Systemic, Lupus NephritisView official trial listing → -
Not yet recruiting NCT NCT07024147
JWCAR239 in Patients With B Cell Non-Hodgkin Lymphoma
Not yet reported Peking University Cancer Hospital & Institute 20 participants Est. completion 2030-07-01 1 site Stand-aloneOther conditions: B-Cell Non-Hodgkin Lymphoma, Large B Cell Diffuse Lymphoma, Follicular Lymphoma, Marginal Zone B Cell Lymphoma, Mantle Cell Lymphoma (MCL)View official trial listing → -
Not yet recruiting NCT NCT07026942
Phase I/II Clinical Trial of Universal Donor CD33 CAR Natural Killer Cells for AML
Not yet reported, Not yet reported Nationwide Children's Hospital 42 participants Est. completion 2038-07-01 1 site Stand-aloneOther conditions: Relapsed/Refractory AMLView official trial listing → -
Enrolling by invitation NCT NCT07038447
A Study of KITE-363 in Participants With Refractory Autoimmune Diseases
Not yet reported Kite, A Gilead Company 52 participants Est. completion 2029-07 8 sites Stand-aloneOther conditions: Systemic Lupus Erythematosus, Lupus Nephritis, Systemic Sclerosis, Idiopathic Inflammatory MyopathyView official trial listing → -
Terminated NCT NCT07049081
A Study of LUCAR-G79 in Subjects With Relapsed/Refractory Autoimmune Diseases
Not yet reported Nanjing Legend Biotech Co. 3 participants Est. completion 2026-03-20 3 sites Stand-aloneOther conditions: Relapsed/Refractory Autoimmune DiseasesView official trial listing → -
Not yet recruiting NCT NCT07052422
VEN+DAC+Bu2Flu4 vs Bu2Flu5 Conditioning Regimen for Elderly Myeloid Malignancies Undergoing Allo-HSCT
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 160 participants Est. completion 2029-12-31 Stand-aloneOther conditions: Older Patients, Myeloid Malignancies, Conditioning, Hematopoietic Stem Cell Transplantation (HSCT)View official trial listing → -
Suspended NCT NCT07055477
A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)
Not yet reported National Cancer Institute (NCI) 60 participants Est. completion 2044-06-01 1 site Stand-aloneOther conditions: Relapsed and/or Refractory Mature T Cell Malignancy, Peripheral T-Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Anaplastic Large Cell Lymphoma, Hepatosplenic T-cell Lymphoma, Monomorphic Epithelialtropic Intestinal Lymphoma, Enteropathy Associated T-cell Lymphoma, Cutaneous T-Cell Lymphoma, Mycosis Fungoides, Subacute Panniculitis-like T-cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT07055724
Study of Eque-cel CAR-T Therapy in Newly Diagnosed Severe AL Amyloidosis
Not yet reported Nanjing IASO Biotechnology Co., Ltd. 17 participants Est. completion 2027-06 Stand-aloneOther conditions: AL AmyloidosisView official trial listing → -
Not yet recruiting NCT NCT07077330
CAR19BCMA CAR-T Cells for the Treatment of R/R Plasma Cell Neoplasms
Not yet reported Chinese PLA General Hospital 20 participants Est. completion 2027-08-01 2 sites Stand-aloneOther conditions: Relapsed or Refractory Plasma Cell NeoplasmsView official trial listing → -
Not yet recruiting NCT NCT07078721
Efficacy and Safety of UCBT With TMI -Based Conditioning Regimen for Adults With Refractory/Relapsed Aplastic Anemia
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 11 participants Est. completion 2028-06 1 site Stand-aloneOther conditions: Aplastic Anemia IdiopathicView official trial listing → -
Not yet recruiting NCT NCT07085156
Reduced Intensity Conditioning for MDS
Not yet reported Ruijin Hospital 45 participants Est. completion 2028-05-01 1 site Stand-aloneOther conditions: MDSView official trial listing → -
Not yet recruiting NCT NCT07091370
Inaticabtagene Autoleucel Injection in the Treatment of Autoimmune Hemolytic Anemia After Three or More Lines of Therapy
Not yet reported Juventas Cell Therapy Ltd. 12 participants Est. completion 2028-03-30 Stand-aloneOther conditions: AIHA - Cold Autoimmune Hemolytic AnemiaView official trial listing → -
Withdrawn NCT NCT07093086
Clinical Study of Multi-targeted CAR-T Therapy in Patients With Relapsed/Refractory B-Cell Lymphoma
Not yet reported Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd Est. completion 2027-01-30 2 sites Stand-aloneOther conditions: B-cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT07104682
A Study to Determine the Safety and Effectiveness of the Investigational Cellular Therapy GCAR1 in a Patient With Alveolar Soft Part Sarcoma
Not yet reported University of Calgary 1 participants Est. completion 2027-01-19 1 site Stand-aloneOther conditions: Alveolar Soft Part Sarcoma (ASPS), SarcomaView official trial listing → -
Not yet recruiting NCT NCT07105176
HS-IT101 Injection for Advanced NSCLC
Not yet reported Hangzhou Huasai Biomedicine Co., Ltd. 12 participants Est. completion 2027-08-30 1 site Stand-aloneOther conditions: Advanced Non-Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT07108140
Engineered T-cell Therapy for Patients With ALPP-Positive Advanced Solid Tumors
Not yet reported TCRCure Biopharma Ltd. 5 participants Est. completion 2026-01-16 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Not yet recruiting NCT NCT07120607
Allogeneic CD7 CAR γδ T Cells Therapy Recurrent/Refractory Leukemia
Not yet reported Anhui Provincial Hospital 9 participants Est. completion 2027-12-31 Stand-aloneOther conditions: LeukemiaView official trial listing → -
Terminated NCT NCT07123493
Engineered T-Cell Therapy for Patients With ALPP-Positive Advanced Solid Tumors
Not yet reported Haifeng Qin 1 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: Recurrent or Metastatic Solid Tumors With Positive ALPPView official trial listing → -
Not yet recruiting NCT NCT07131085
QH101 Cell Therapy Relapsed/Refractory(R/R) Acute Myeloid Leukemia(AML) and Myelodysplastic Syndromes(MDS)
Not yet reported Anhui Provincial Hospital 9 participants Est. completion 2027-12-31 Stand-aloneOther conditions: MDS, AMLView official trial listing → -
Not yet recruiting NCT NCT07137481
Phase II Study of CD5 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Aggressive T Cell Hematological Malignancies
Not yet reported M.D. Anderson Cancer Center 70 participants Est. completion 2032-07-31 1 site Stand-aloneOther conditions: Hematological MalignanciesView official trial listing → -
Active, not recruiting NCT NCT07139600
Multi-omics Profiling of Patients With Aplastic Anemia Before and After CD7-CAR-T Therapy
Xuzhou Medical University 5 participants Est. completion 2027-07-31 1 siteOther conditions: Aplastic Anaemia, CAR-T, CD7 PositiveView official trial listing → -
Active, not recruiting NCT NCT07142161
A Study on the Safety, Preliminary Efficacy, and Cellular Kinetics of Allo-CD7 CAR-T Cells in T1DM
Not yet reported Nanjing Bioheng Biotech Co., Ltd. 3 participants Est. completion 2026-12-25 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Not yet recruiting NCT NCT07153289
CD318-targeted CAR-T Cell Therapy in Patients With Pancreatic Cancer (ResCPa)
Not yet reported, Not yet reported University Hospital Tuebingen 38 participants Est. completion 2028-12 Stand-aloneOther conditions: Carcinoma, Pancreatic Ductal, Pancreatic NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT07155369
UCAR T-cell Therapy Targeting CD19/ BCMA in Patients With Relapse/ Refractory Autoimmune Diseases
Not yet reported The Affiliated Hospital of Xuzhou Medical University 18 participants Est. completion 2028-09 1 site Stand-aloneOther conditions: Systemic Lupus Erythematosus, Systemic SclerosisView official trial listing → -
Completed NCT NCT07155382
Allogeneic HCT Using Conditioning Regimen of BuFluATG for AML CR1
Asan Medical Center 98 participants Est. completion 2024-08-22 1 siteOther conditions: Acute Myeloid Leukemia (AML)View official trial listing → -
Not yet recruiting NCT NCT07157514
Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML
Not yet reported, Not yet reported Actinium Pharmaceuticals 306 participants Est. completion 2034-02 Stand-aloneOther conditions: Acute Leukemia, Myeloid Leukemia, Acute Myelogenous Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia, in Relapse, Myelogenous Leukemia, Myelogenous Leukemia, Acute, Myelogenous Leukemia in Relapse, Transplant-Related Disorder, Allogeneic Disease, Refractory AMLView official trial listing → -
Not yet recruiting NCT NCT07161193
Anti-CD19 Chimeric Antigen Receptor T Cells for Refractory Autoimmune Diseases
Not yet reported, Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 30 participants Est. completion 2027-11-18 1 site Stand-aloneOther conditions: Autoimmune DiseasesView official trial listing → -
Not yet recruiting NCT NCT07162571
This is a Phase I/II Interventional, Open-label Treatment Study Designed to Evaluate the Safety and Efficacy of Anti CD 19/22 CAR- T Cells Immunotherapy for Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia/Lymphoma.
Not yet reported, Not yet reported Minsk Scientific-Practical Center for Surgery, Transplantation and Hematology 17 participants Est. completion 2031-12 1 site Stand-aloneOther conditions: Acute Lymphobkastic Leukemia, B Cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT07164469
Phase 2 Trial of CD70.CAR NK Cells for Patients With Primary Refractory or Early Relapsed Diffuse Large B-Cell Lymphoma and Hodgkin Lymphoma
Not yet reported M.D. Anderson Cancer Center 100 participants Est. completion 2033-09-30 1 site Stand-aloneOther conditions: Large B-cell Lymphoma, Hodgkin LymphomaView official trial listing → -
Active, not recruiting NCT NCT07166419
Anti-CD19/20/22 Chimeric Antigen Receptor T Cells (TriCAR19.20.22 T Cells) for the Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma, Acute Lymphoblastic Leukemia, and Chronic Lymphocytic Leukemia
Not yet reported Ohio State University Comprehensive Cancer Center 24 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive, Recurrent Acute Lymphoblastic Leukemia, Recurrent Chronic Lymphocytic Leukemia, Recurrent Chronic Myeloid Leukemia, BCR-ABL1 Positive, Recurrent Indolent Non-Hodgkin Lymphoma, Recurrent Lymphoblastic Lymphoma, Recurrent Non-Hodgkin Lymphoma, Recurrent Transformed Chronic Lymphocytic Leukemia, Refractory Acute Lymphoblastic Leukemia, Refractory Chronic Lymphocytic Leukemia, Refractory Chronic Myeloid Leukemia, BCR-ABL1 Positive, Refractory Indolent Non-Hodgkin Lymphoma, Refractory Lymphoblastic Lymphoma, Refractory Non-Hodgkin Lymphoma, Refractory Transformed Chronic Lymphocytic LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07166549
Bispecific CAR T Cells for B-cell Malignancies (BaseCAR-01 Trial)
Not yet reported University Hospital, Basel, Switzerland 12 participants Est. completion 2028-11 1 site Stand-aloneOther conditions: B Cell Malignancies, B-cell Leukemia, B Cell Lymphoma, Bispecific Chimeric Antigen Receptor (CAR) T Cells, Relapsed or Refractory (r/r) B-cell MalignanciesView official trial listing → -
Not yet recruiting NCT NCT07168291
Novel Bispecific AbTCR (Anti-CD19/CD22)-T Cells in Relapsed or Refractory B-cell Lymphoma
Not yet reported First Affiliated Hospital Xi'an Jiaotong University 3 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Diffuse Large B Cell Lymphoma (DLBCL), Follicular Lymphoma ( FL), Burkitt LymphomaView official trial listing → -
Enrolling by invitation NCT NCT07168486
CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas
Not yet reported University of Maryland, Baltimore 15 participants Est. completion 2028-07-01 1 site Stand-aloneOther conditions: B-Cell Lymphoma, Diffuse Large B Cell Lymphoma (DLBCL), Primary Mediastinal Large B-cell Lymphoma (PMBCL), Follicular Lymphoma, Transformed Follicular Lymphoma (tFL), Mantle Cell Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Richter Transformation, Marginal Zone LymphomaView official trial listing → -
Suspended NCT NCT07181720
CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid Tumors
Not yet reported Chongqing Precision Biotech Co., Ltd 90 participants Est. completion 2028-05-31 1 site Stand-aloneOther conditions: Renal Cell Carcinoma (RCC), Lung Cancer, Anaplastic Thyroid Carcinomas, Ovarian Cancer, Cervical Cancer, Thymic CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07214064
Venetoclax- Augmented Treosulfan-Based Reduced Intensity Conditioning Before Allogeneic Stem Cell Transplantation
Not yet reported University Hospital Tuebingen 27 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: AML (Acute Myeloid Leukemia), MDS/AML, MDS (Myelodysplastic Syndrome)View official trial listing → -
Active, not recruiting NCT NCT07232953
Safety and Efficacy of FT14 Conditioning for Allogeneic HSCT in Acute Myeloid Leukemia
Not yet reported Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia 82 participants Est. completion 2027-06 13 sites Stand-aloneOther conditions: Acute Myeloid Leukaemia (AML), Hematopoietic Stem Cell Transplant (HSCT)View official trial listing → -
Enrolling by invitation NCT NCT07240857
A Clinical Study Evaluating the Safety and Efficacy of Local Injection of ACT#001 Chimeric Antigen Receptor T Cells in the Treatment of Castration-Resistant Prostate Cancer
Not yet reported Zhejiang University 18 participants Est. completion 2027-10-31 1 site Stand-aloneOther conditions: Castration-Resistant Prostate Cancer (CRPC)View official trial listing → -
Not yet recruiting NCT NCT07259161
Modified Conditioning Regimen for CML-BP
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 40 participants Est. completion 2029-09-14 Stand-aloneOther conditions: CML,Blast Phase, HSCTView official trial listing → -
Not yet recruiting NCT NCT07265206
A Study of HY001N in the Treatment of Relapsed or Refractory Neurological Autoimmune Diseases
Not yet reported Juventas Cell Therapy Ltd. 15 participants Est. completion 2028-12-30 Stand-aloneOther conditions: Neurological Autoimmune DiseasesView official trial listing → -
Not yet recruiting NCT NCT07298590
An Exploratory Clinical Study on the Safety and Efficacy of CD19/BCMA CAR-NK in the Treatment of Relapsed and Refractory IgG4-related Disease
Not yet reported Changhai Hospital 18 participants Est. completion 2028-12-26 1 site Stand-aloneOther conditions: IgG4 Related DiseaseView official trial listing → -
Not yet recruiting NCT NCT07324889
An Open-label, Single-arm, Prospective, Multicenter, Phase I/II Clinical Study on the Safety and Efficacy of CD19/BCMA CAR-T Cell Therapy for Relapsed/Refractory Warm Antibody Autoimmune Hemolytic Anemia
Not yet reported, Not yet reported Yihao Wang 24 participants Est. completion 2027-10-31Other conditions: Relapsed/Refractory Warm Antibody Autoimmune Hemolytic AnemiaView official trial listing → -
Not yet recruiting NCT NCT07333820
Clinical Study to Evaluate the Safety and Anti-Tumor Activity of AB-201
Not yet reported Yonsei University 18 participants Est. completion 2028-03 1 site Stand-aloneOther conditions: Malignant Neoplasm of Stomach, UnspecifiedView official trial listing → -
Not yet recruiting NCT NCT07335094
A Clinical Study of Humanized CD19 CAR-T Cells With TLR2 for the Treatment of Adult Patients With Naive B-Cell Acute Lymphoblastic Leukemia/Lymphoma Who Are Intolerant to Intensive Chemotherapy
Not yet reported Zhujiang Hospital 60 participants Est. completion 2029-06-01 Stand-aloneOther conditions: B Lymphoblastic Leukemia/LymphomaView official trial listing → -
Not yet recruiting NCT NCT07335562
A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 92 participants Est. completion 2030-11-11 56 sites Stand-aloneOther conditions: Systemic SclerosisView official trial listing → -
Not yet recruiting NCT NCT07336875
Clinical Study of Novel CAR-ITNK Cells Targeting CD70 and CLL1 for Refractory/Relapsed AML
Not yet reported Tongji Hospital 30 participants Est. completion 2029-02-28 Stand-aloneOther conditions: R/R AMLView official trial listing → -
Suspended NCT NCT07340853
CRISPR Delivered Anti-BCMA Car-T Therapy for Relapsed or Refractory Multiple Myeloma
Not yet reported Thomas Martin, MD 30 participants Est. completion 2043-05-25 1 site Stand-aloneOther conditions: Multiple Myeloma, Recurrent Multiple Myeloma, Refractory Multiple MyelomaView official trial listing → -
Not yet recruiting NCT NCT07342738
TCR-T Cell Therapy for KRAS Mutation in Advanced Solid Tumors
Not yet reported Sun Yat-sen University 25 participants Est. completion 2029-02-01 1 site Stand-aloneOther conditions: KRAS G12V, KRAS G12D, Solid TumorView official trial listing → -
Not yet recruiting NCT NCT07358195
Addition of Venetoclax to Combined Hematopoietic Stem Cell and Kidney Transplantation
Not yet reported Massachusetts General Hospital 3 participants Est. completion 2029-12 1 site Stand-aloneOther conditions: Kidney Failure Chronic, Stem Cell Transplant, Stem Cell Transplant Complications, Tolerance, Hematologic CancerView official trial listing → -
Not yet recruiting NCT NCT07367685
Clinical Study of Universal CD19 CAR-γδT Cell Injection in the Treatment of Adult Relapsed/Refractory B-cell Lymphoma
Not yet reported The Second Affiliated Hospital of Fujian Medical University 6 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Recurrent/Refractory B-cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT07372885
GRanulocyte Augmented Cord Blood Transplantation for Poor Risk leukaEmia
Not yet reported, Not yet reported University of Manchester 50 participants Est. completion 2029-12-31 3 sites Stand-aloneOther conditions: Acute Myeloid Leukemia, Stem Cell Transplantation, Stem Cell Transplantation, Hematopoietic, Cord Blood Stem Cell Transplantation, Cellular TherapyView official trial listing → -
Active, not recruiting NCT NCT07388277
CC-97540 in Patients With Antineutrophil Cytoplasmic Antibody-associated Vasculitis
Not yet reported, Not yet reported Marcela V. Maus, M.D.,Ph.D. 12 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Antineutrophil Cytoplasmic Antibody-associated VasculitisView official trial listing → -
Not yet recruiting NCT NCT07406724
HS-IT101 Injection Versus Chemotherapy in the Treatment of Advanced Melanoma
Not yet reported Hangzhou Huasai Biomedicine Co., Ltd. 90 participants Est. completion 2028-12-31 Stand-aloneOther conditions: Melanoma (Excluding Uveal Melanoma)View official trial listing → -
Not yet recruiting NCT NCT07406984
Clinical Study of IM96 CAR-T Cell Therapy in Patients With Advanced Adenocarcinoma of Gastric/Esophagogastric Junction
Not yet reported Beijing Immunochina Medical Science & Technology Co., Ltd. 18 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Adenocarcinoma of Gastric, Adenocarcinoma of Esophagogastric JunctionView official trial listing → -
Not yet recruiting NCT NCT07421856
Phase I/II Study of SENL103 for Relapsed or Refractory Multiple Myeloma: A Multicenter, Open-Label, Single-Arm Trial.
Not yet reported, Not yet reported Hebei Senlang Biotechnology Inc., Ltd. 24 participants Est. completion 2030-02-01 Stand-aloneOther conditions: Multiple Myeloma in Relapse, Multiple Myeloma RefractoryView official trial listing → -
Not yet recruiting NCT NCT07423572
Clinical Study of Anti-CD19/BCMA Universal Chimeric Antigen Receptor T Cells (UCAR-T) in the Treatment of Refractory Idiopathic Membranous Nephropathy (IMN)
Not yet reported The First Affiliated Hospital of Zhejiang Chinese Medical University 18 participants Est. completion 2029-09-28 1 site Stand-aloneOther conditions: Refractory Idiopathic Membranous NephropathyView official trial listing → -
Withdrawn NCT NCT07428486
A Phase 1 Study Of FLAG Chemotherapy In Combination With Lisaftoclax And Pelcitoclax In Patients With Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia
Not yet reported M.D. Anderson Cancer Center Est. completion 2026-04-27 Stand-aloneOther conditions: Phase I, FLAG Chemotherapy, Lisaftoclax, Pelcitoclax, Relapsed/Refractory, Lymphoblastic Leukemia AcuteView official trial listing → -
Not yet recruiting NCT NCT07441967
The Safety and Efficacy of the Regimen of Thiotepa + Fludarabine +Granulocyte Colony-Stimulating Factor+ Cytarabine + Busulfan in Single Unrelated Umbilical Cord Blood Transplantation
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 44 participants Est. completion 2028-12-30 Stand-aloneOther conditions: Hematologic MalignanciesView official trial listing → -
Not yet recruiting NCT NCT07447726
Exploratory Clinical Study on the Safety and Efficacy of CD19X CAR-T Cell Injection in the Treatment of Relapsed/Refractory Large B-Cell Lymphoma
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 3 participants Est. completion 2028-01-01Other conditions: Large B-Cell Lymphoma (LBCL)View official trial listing → -
Withdrawn NCT NCT07453446
Clinical Study of U29 Injection (CD30-CART) in Patients With CD30-Positive Relapsed/Refractory Lymphoma
Not yet reported Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd Est. completion 2029-03-31 1 site Stand-aloneOther conditions: Relapsed or Refractory LymphomaView official trial listing → -
Not yet recruiting NCT NCT07487402
Safety and Efficacy of Metabolically Armed GPC3 CAR-T Cells Injection (Meta10-GPC3) in Patients With Unresectable Recurrent/Metastatic Hepatocellular Carcinoma
Not yet reported Zhejiang University 27 participants Est. completion 2029-04-15 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Not yet recruiting NCT NCT07490275
Allogeneic CD19/BCMA-Targeted CAR-γδT Cell Therapy: Safety and Preliminary Pharmacodynamics in Relapsed/Refractory Autoimmune Diseases
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 9 participants Est. completion 2028-12-31 Stand-aloneOther conditions: Refractory/Relapsed Systemic Lupus Erythematosus, Refractory / Relapsed / Progressive Systemic Sclerosis, Refractory / Relapsing / Progressive Inflammatory Myopathy, Refractory / Relapsed Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis, Refractory / Relapsed Connective Tissue Disease-Associated ThrombocytopeniaView official trial listing → -
Not yet recruiting NCT NCT07491263
Clinical Study of Universal CD19 CAR-γδ T Cell Infusion in the Treatment of Relapsed/Refractory Acute B Lymphoblastic Leukemia
Not yet reported Fujian Medical University 6 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Relapsed/Refractory CD19-positive B-ALLView official trial listing → -
Not yet recruiting NCT NCT07500805
UCL70805F in Patients With CD70-positive Advanced Renal Clear Cell Carcinoma
Not yet reported UTC Therapeutics Inc. 21 participants Est. completion 2029-05-01 1 site Stand-aloneOther conditions: CD70-positive Advanced Renal Clear Cell CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07509008
Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum
Not yet reported, Not yet reported M.D. Anderson Cancer Center 10 participants Est. completion 2030-07-01 1 site Stand-aloneOther conditions: Gastric Cancer, MetastaticView official trial listing → -
Enrolling by invitation NCT NCT07517536
CHT105 for the Treatment of Refractory Lupus Nephritis
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 14 participants Est. completion 2028-01 1 site Stand-aloneOther conditions: Systemic Lupus Erythematosus, Lupus NephritisView official trial listing → -
Not yet recruiting NCT NCT07518329
Study of ALA-101 in Patients With CD19 Positive Non-Hodgkin Lymphoma and Leukemia.
Not yet reported Arovella Therapeutics Ltd 46 participants Est. completion 2030-08-30 5 sites Stand-aloneOther conditions: Non Hodgkin Lymphoma (NHL), LeukaemiaView official trial listing → -
Not yet recruiting NCT NCT07524530
Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers
Not yet reported National Cancer Institute (NCI) 102 participants Est. completion 2036-06-01 1 site Stand-aloneOther conditions: Core Binding Factor Alpha Subunits, Hematologic Neoplasms, Leukemia, LymphomaView official trial listing → -
Suspended NCT NCT07527936
A Study of BEN301 Injection in theTreatment of Autoimmune Diseases
Not yet reported RenJi Hospital 24 participants Est. completion 2029-02-28 1 site Stand-aloneOther conditions: Systemic Sclerosis (SSc), Rheumatoid Arthritis (RA), Sjogren's Syndrome (SS), Idiopathic Inflammatory Myopathies(IIM)View official trial listing → -
Not yet recruiting NCT NCT07535138
Efficacy and Safety of CD19 CAR-γδ T Cells in the Treatment of Relapsed/Refractory Autoimmune Nephropathy
Not yet reported Air Force Military Medical University, China 15 participants Est. completion 2028-12-30 1 site Stand-aloneOther conditions: Membranous Nephropathy, Lupus Nephritis (LN), IgA Nephropathy (IgAN)View official trial listing → -
Enrolling by invitation NCT NCT07539662
Unrelated Umbilical Cord Blood Transplantation for the Treatment of Amyotrophic Lateral Sclerosis (ALS)
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 8 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: ALS (Amyotrophic Lateral Sclerosis)View official trial listing → -
Not yet recruiting NCT NCT07539688
Phase I Clinical Study on the Safety and Efficacy of CY-219 CAR-T Cell Injection in the Treatment of Relapsed/Refractory B-Cell Lymphoma
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 18 participants Est. completion 2029-12-01Other conditions: Relapsed/Refractory B-cell Lymphoma, Diffuse Large B-cell Lymphoma, Inert B-cell Lymphoma Transformed Into Large B-cell Lymphoma (Excluding Richter Transformation, THRLBCL, and BL)View official trial listing → -
Not yet recruiting NCT NCT07546630
Nanobody-Based CD19/CD20 Tandem Dual CAR-T-cell Therapy of Relapsed/Refractory B-Cell Lymphoma
Not yet reported Affiliated Hospital to Academy of Military Medical Sciences 20 participants Est. completion 2029-05-01 Stand-aloneOther conditions: Relapsed/Refractory B-Cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT07562568
SHR2554/AZA + Overlapped TBF for High-risk/Relapsed Leukemia/MDS
Not yet reported The First Affiliated Hospital of Soochow University 160 participants Est. completion 2030-06 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, MDS, Transplantation, Stem Cell, Conditioning Therapy, SHR2554, AzacytidineView official trial listing → -
Not yet recruiting NCT NCT07563920
TBF Conditioning Regimen for Haploidentical Stem Cell Transplantation in Elderly AML Patients in First Complete Remission
Not yet reported Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 93 participants Est. completion 2030-06 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07569965
Frontline Risk-Adapted Optimization of Novel Targeted Immunotherapy Evaluation in High-Risk MCL
Not yet reported Miltenyi Biomedicine GmbH 52 participants Est. completion 2030-03 Stand-aloneOther conditions: Mantle Cell Lymphoma (MCL)View official trial listing → -
Not yet recruiting NCT NCT07572695
Salvage Haploidentical HSCT With DLI and Targeted Therapy for R/R AML
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 40 participants Est. completion 2028-12Other conditions: Acute Myeloid Leukemia, Relapsed/Refractory Acute Myeloid Leukemia, AML, Relapsed/RefractoryView official trial listing → -
Not yet recruiting NCT NCT07573332
A Safety and Tolerability Study of CC- 97540 (BMS-086353) in Anti-Aquaporin 4 Antibody Positive Neuromyelitis Optica Patients
Not yet reported University of Texas Southwestern Medical Center 5 participants Est. completion 2031-08-01 1 site Stand-aloneOther conditions: AQP4+ NMOSDView official trial listing → -
Not yet recruiting NCT NCT07575893
CD30 CAR-T Cells for Low Risk Relapsed Classical Hodgkin Lymphoma
Not yet reported New York Medical College 12 participants Est. completion 2032-12-01 Stand-aloneOther conditions: Classical Hodgkin LymphomaView official trial listing → -
Not yet recruiting NCT NCT07583303
BSB-2002 After Cyclophosphamide and Fludarabine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With NPM1 Mutation
Not yet reported City of Hope Medical Center 19 participants Est. completion 2027-04-16 1 site Stand-aloneOther conditions: Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07593482
Bendamustine Versus Fludarabine/Cyclophosphamide for Lymphodepletion in Chimeric Antigen Receptor T-cell Immunotherapy (CAR-T): a Randomized Trial.
Not yet reported Swiss Cancer Institute 92 participants Est. completion 2030-03 9 sitesOther conditions: B-cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT07598110
FLUDARABINE-TREOSULFAN REDUCED INTENSITY CONDITIONING REGIMEN PRIOR HAPLOIDENTICAL STEM CELL TRANSPLANTATION WITH POST TRANSPLANTATION CYCLOPHOSPHAMIDE FOR OLDER AND/OR FRAIL PATIENTS WITH AML
Not yet reported Institut Paoli-Calmettes 77 participants Est. completion 2031-02-10 Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07603557
Study of Zola-cel (BMS-986353), in Participants With Autoimmune Cytopenia (Breakfree-AiCE)
Not yet reported Juno Therapeutics, Inc., a Bristol-Myers Squibb Company 52 participants Est. completion 2030-05-06 8 sites Stand-aloneOther conditions: Chronic Immune Thrombocytopenia, Autoimmune Hemolytic AnemiaView official trial listing → -
Not yet recruiting NCT NCT07604233
Phase 1/2 FLAG-IDA, VEN and Asciminib in CML and Ph+ AML
Not yet reported, Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2033-06-03 1 site Stand-aloneOther conditions: Myeloid LeukemiaView official trial listing → -
Not yet recruiting NCT NCT07613788
Rimegepant Plus Glofitamab and CD19 CAR-T Therapy in R/R LBCL
Not yet reported Ruijin Hospital 100 participants Est. completion 2029-04 1 site Stand-aloneOther conditions: Relapsed/Refractory Large B-cell Lymphoma (LBCL)View official trial listing → -
Available NCT NCT07614048
Intermediate-size IND for Treatment of Patients With Advanced Cancer Using T Cells Engineered to Express TCR Targeting Mutant KRAS
Providence Health & ServicesOther conditions: PDAC - Pancreatic Ductal Adenocarcinoma, Colorectal CancerView official trial listing → -
Not yet recruiting NCT NCT07622862
Exploratory Clinical Trial of DQ1001 in Relapsed or Refractory Multiple Myeloma (RRMM)
Not yet reported Zhongshan Hospital (Xiamen), Fudan University 16 participants Est. completion 2028-08 Stand-aloneOther conditions: Multiple Myeloma Refractory, Multiple Myeloma ProgressionView official trial listing → -
Not yet recruiting NCT NCT07624799
Fixed Duration Treatment With Combined Pirtobrutinib and Short Course Immuno-chemotherapy in Fit Patients With Previously Untreated Symptomatic Chronic Lymphocytic Leukemia (CLL).
Not yet reported French Innovative Leukemia Organisation 82 participants Est. completion 2033-09-01 Stand-aloneOther conditions: CLL (Chronic Lymphocytic Leukemia)View official trial listing → -
Not yet recruiting NCT NCT07634536
Automated Total Marrow and Lymphoid Irradiation for Allogeneic Hematopoietic Cell Transplant
Not yet reported Stanford University 30 participants Est. completion 2028-08 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myeloproliferative Neoplasm, Myelodysplastic SyndromesView official trial listing → -
Not yet recruiting NCT NCT07647068
Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors
Not yet reported Joal Beane 59 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Locally Advanced Gastrointestinal Stromal Tumor, Metastatic Gastrointestinal Stromal Tumor, Recurrent Gastrointestinal Stromal Tumor, Refractory Malignant Gastrointestinal Stromal Tumor, Unresectable Malignant Gastrointestinal Stromal TumorView official trial listing → -
Not yet recruiting NCT NCT07651618
A Phase II Trial of Tumour Infiltrating Lymphocyte Adoptive Cell Therapy in Patients With Immune Checkpoint Inhibitor Resistant Unresectable or Metastatic Melanoma
Not yet reported East Metropolitan Health Service, Australia 10 participants Est. completion 2032-04 1 site Stand-aloneOther conditions: Melanoma (Skin Cancer), Melanoma MetastaticView official trial listing → -
Not yet recruiting NCT NCT07660783
Naive T Cell Deplete Grafts for GVHD Prevention in Non-Malignant Diseases
Not yet reported Fred Hutchinson Cancer Center 40 participants Est. completion 2035-09 2 sitesOther conditions: Bone Marrow Failure, Hemoglobinopathies, Primary Immune Deficiency (PID), Autoimmune Cytopenia, Immune Dysregulation, Hemophagocytic Lymphohistiocytosis (HLH), Non Malignant DisordersView official trial listing → -
Not yet recruiting NCT NCT07670260
GoFast CAR T-Cell Therapy for Recurrent Refractory B-Cell Lymphoma
Not yet reported Chinese PLA General Hospital 9 participants Est. completion 2028-06-30 1 site Stand-aloneOther conditions: Relapsed or Refractory Large B-cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT07672483
IL-12 Genetically Engineered Myeloid Cells in Participants With Relapsed, Refractory Solid Tumors
Not yet reported National Cancer Institute (NCI) 95 participants Est. completion 2029-01-15 1 site Stand-aloneOther conditions: Relapsed Solid Tumor Malignancies, Refractory Solid Tumor MalignanciesView official trial listing → -
Not yet recruiting NCT NCT07674147
RD06-05 Universal CD19/BCMA CAR-T for Refractory Pediatric Autoimmune Diseases
Not yet reported The Children's Hospital of Zhejiang University School of Medicine 30 participants Est. completion 2030-07 2 sites Stand-aloneOther conditions: Autoimmune Diseases, SLE - Systemic Lupus Erythematosus, SSc-Systemic Sclerosis, IIM- Idiopathic Inflammatory Myopathies, IgAN - IgA Nephropathy, Multi-Drug Resistant Nephrotic SyndromeView official trial listing → -
Not yet recruiting NCT NCT07676877
Lymphodepletion With Low Dose Total Body Irradiation Before Standard of Care Tisagenlecleucel for the Treatment of Relapsed and Recurrent Large B-cell Lymphoma
Not yet reported Nathan Denlinger 18 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Recurrent Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT07678307
A Multicenter, Open-label, Non-randomized, Single-arm Phase 1/2 Study of Autologous Nano CD5-CAR T Cells for the Treatment of Relapsed/Refractory T-cell Acute Lymphoblastic Leukemia/Lymphoma
Not yet reported, Not yet reported Institute of Hematology & Blood Diseases Hospital, China 18 participants Est. completion 2027-12-31 Stand-aloneOther conditions: T-Cell Acute Lymphoblastic Leukemia, T-Lymphoblastic Lymphoma, Relapsed/Refractory Hematologic MalignanciesView official trial listing → -
Not yet recruiting NCT NCT07686107
Trial of Revumenib Plus FLA Chemotherapy for Children With Relapsed or Refractory NUP98-rearranged AML."
Not yet reported Therapeutic Advances in Childhood Leukemia Consortium 24 participants Est. completion 2030-12-31 Stand-aloneOther conditions: Leukemia, Myeloid, AcuteView official trial listing → -
Not yet recruiting NCT NCT07711483
GLORY: Glofit-GemOx With Liso-Cel For Lymphoma
Not yet reported Massachusetts General Hospital 56 participants Est. completion 2030-10-01 2 sites Stand-aloneOther conditions: Lymphoma, B-cell Lymphomas, Relapsed/Refractory Large B-cell Lymphoma, Large B-cell LymphomaView official trial listing → -
Not yet recruiting NCT NCT07720180
Study of Autologous, Metabolically Optimized, CD137+ Tumor-Infiltrating Lymphocytes Followed by Consolidative Oral Cyclophosphamide, Bevacizumab, and Pembrolizumab
Not yet reported Medical University of South Carolina 20 participants Est. completion 2032-12-01 1 site Stand-aloneOther conditions: Ovarian CancerView official trial listing → -
Not yet recruiting NCT NCT07725406
Low-Dose TBI Plus CAR T-Cell Therapy for Relapsed/Refractory DLBCL and Multiple Myeloma
Not yet reported Weill Medical College of Cornell University 32 participants Est. completion 2033-08-31 1 site Stand-aloneOther conditions: Relapsed or Refractory Diffuse Large B Cell Lymphoma (DLBCL), Relapsed or Refractory Multiple Myeloma (MM)View official trial listing → -
Not yet recruiting NCT NCT07729826
C-CAR168 CAR T-Cell Therapy for the Treatment of Lupus Nephritis Refractory to Standard Therapy
Not yet reported AbelZeta Inc. 50 participants Est. completion 2029-09-01 Stand-aloneOther conditions: Lupus Nephritis (LN), Systemic Lupus Erythematosus (SLE), Autoimmune DiseasesView official trial listing → -
Not yet recruiting NCT NCT07737769
Arsenic Trioxide to Prevent Relapse in Patients Undergoing Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia or Myelodysplastic Syndrome
Not yet reported University of Michigan Rogel Cancer Center 20 participants Est. completion 2029-11 1 site Stand-aloneOther conditions: Acute Myeloid Leukemia, Myelodysplastic SyndromeView official trial listing → -
Not yet recruiting NCT NCT07741877
A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Soft Tissue Sarcoma
Not yet reported Iovance Biotherapeutics, Inc. 80 participants Est. completion 2034-09-01 Stand-aloneObstructive sleep apnea Other conditions: Sarcoma, Soft Tissue Sarcoma (STS), Advanced Soft Tissue Sarcoma, Undifferentiated Pleomorphic Sarcoma (UPS)View official trial listing → -
Not yet recruiting NCT NCT07757685
Autologous Hematopoietic Stem Cell Transplantation for Neurological Damage Associated With Hereditary Homocysteine Remethylation Disorders
Not yet reported Institute of Hematology & Blood Diseases Hospital, China 50 participants Est. completion 2030-07-31 2 sites Stand-aloneOther conditions: Hereditary Homocysteine Remethylation DisorderView official trial listing → -
Not yet recruiting NCT NCT07758673
Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma
Not yet reported City of Hope Medical Center 16 participants Est. completion 2028-07-26 2 sites Stand-aloneOther conditions: Recurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma, Refractory B Acute Lymphoblastic Leukemia, Refractory B Lymphoblastic LymphomaView official trial listing → -
Not yet recruiting NCT NCT07759102
Allogeneic ORCA-Q Stem Cell Transplant for the Treatment of Relapsed and Refractory High Risk Multiple Myeloma
Not yet reported University of California, Davis 20 participants Est. completion 2033-09-01 1 site Stand-aloneOther conditions: Recurrent Multiple Myeloma, Refractory Multiple MyelomaView official trial listing → -
Not yet recruiting NCT NCT07766850
Addition of Hydroxyurea to Fludarabine, Cytarabine, Idarubicin and Venetoclax Salvage Therapy for Adults With Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported Christer C Nilsson 26 participants Est. completion 2034-09 1 site Stand-aloneOther conditions: R/R AMLView official trial listing → -
Not yet recruiting NCT NCT07793435
A Phase 1/2 Trial of ADI-212 in mCRPC
Not yet reported, Not yet reported Adicet Therapeutics 12 participants Est. completion 2029-10 1 site Stand-aloneOther conditions: Prostate Cancer MetastaticView official trial listing → -
Not yet recruiting NCT NCT07819396
Depletion of CD45RA Positive Naive T Cells for the Prevention of Graft Versus Host Disease in Older Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Acute Leukemia or Myelodysplastic Syndrome
Not yet reported Fred Hutchinson Cancer Center 52 participants Est. completion 2031-06-01 1 site Stand-aloneOther conditions: Acute Biphenotypic Leukemia, Acute Leukemia, Acute Leukemia of Ambiguous Lineage, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Undifferentiated Leukemia, Blastic Plasmacytoid Dendritic Cell Neoplasm, Burkitt Leukemia, Burkitt Lymphoma, Chronic Myeloid Leukemia, BCR-ABL1 Positive, Lymphoblastic Lymphoma, Mast Cell Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic SyndromeView official trial listing → -
Not yet recruiting NCT NCT07825389
A Study of C-CAR168 in Participants With Progressive Multiple Sclerosis
Not yet reported, Not yet reported AbelZeta Inc. 119 participants Est. completion 2030-02 Stand-aloneOther conditions: Multiple SclerosisView official trial listing → -
Active, not recruiting NCT NCT07826585
Treatment of Patients With Advanced Solid Tumors Using CRTKVA11-03 TCR-T Cell Injection
Not yet reported Corregene Biotechnology Co., Ltd 6 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Not yet recruiting NCT NCT07854483
A Phase 1b Study of C-CAR168 in Participants With Systemic Sclerosis (SSc)
Not yet reported AbelZeta Inc. 12 participants Est. completion 2030-03 Stand-aloneOther conditions: Systemic Sclerosis (SSc), Systemic Sclerosis, Systemic Sclerosis (Scleroderma), Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria, Systemic Sclerosis Pulmonary, Systemic Sclerosis With Lung InvolvementView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Fludarabine Phosphate, Fludarabine, Fludara
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
