About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Febuxostat
- Company
- Mostafa Bahaa
- Mechanism
- Mechanism not yet reported
- Route
- Oral
- Recruiting trials
- 9 recruiting
Efficacy results: Not yet reported
9 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 18, 2026
Find a Clinical Trial Near Me
See recruiting studies for Febuxostat and check eligibility with the study team.
Trial details
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Recruiting NCT NCT05109936
Immediate Prescription of a Hypouricemic Treatment, Febuxostat, Compared to Its Delayed Administration
Not yet reported University Hospital, Rouen 128 participants Est. completion 2027-01-01 6 sites Stand-aloneOther conditions: GoutView official trial listing → -
Recruiting NCT NCT06622603
the Effects of Febuxostat Dose Tapering in Gout Patients Optimally Controlled for 5 Years or More
Not yet reported Seoul National University Hospital 59 participants Est. completion 2027-08-19 1 siteOther conditions: Gout, Uric AcidView official trial listing → -
Recruiting NCT NCT06669000
Time Required to Dissolve Urate Deposits
Assistance Publique - Hôpitaux de Paris 250 participants Est. completion 2032-09-24 1 siteOther conditions: GoutView official trial listing → -
Recruiting NCT NCT06834230
Effect of Dotinurad in Hyperuricemia With Hypertension
Not yet reported Saga University 360 participants Est. completion 2030-03-31 1 siteOther conditions: Hyperuricemia or Gout, HypertensionView official trial listing → -
Recruiting NCT NCT06966635
Exploratory Study on the Treatment of Gout With Potassium Citrate Sustained-release Tablets
Not yet reported Huashan Hospital 312 participants Est. completion 2026-04-30 1 site Stand-aloneOther conditions: Hyperuricemia or Gout, NephrolithiasisView official trial listing → -
Recruiting NCT NCT07170475
A Phase Ib Trial of Combined Febuxostat and Inosine Therapy in Patients With Parkinson's Disease
Not yet reported Fujita Health University 24 participants Est. completion 2026-07-31 1 site Stand-aloneOther conditions: Parkinson's Disease (PD)View official trial listing → -
Recruiting NCT NCT07362355
The Efficacy and Safety of SHR4640 Tablet Combined With 40 mg Febuxostat Tablets in the Treatment of Primary Gout and Hyperuricemia
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 340 participants Est. completion 2027-07 1 site Stand-aloneOther conditions: Primary Gout and HyperuricemiaView official trial listing → -
Recruiting NCT NCT07485452
Boosting Osimertinib Blood Brain Barrier Penetration
Not yet reported Maastricht University Medical Center 7 participants Est. completion 2028-06 2 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT07701512
Clinical Study to Evaluate the Efficacy of Febuxostat in the Treatment of Conservatively Managed Intracranial Hemorrhage Patients
Not yet reported Tanta University 46 participants Est. completion 2027-01-30 1 site Stand-aloneOther conditions: Intracranial HemorrhageView official trial listing → -
Completed NCT NCT00102440
Febuxostat Versus Allopurinol Control Trial in Subjects With Gout
Not yet reported Takeda 760 participants Est. completion 2004-02 Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT00174915
Phase 3, Febuxostat, Allopurinol and Placebo-Controlled Study in Gout Subjects.
Not yet reported Takeda 1072 participants Est. completion 2004-04 Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT00174941
Long-Term Safety of Febuxostat in Subjects With Gout.
Not yet reported Takeda 116 participants Est. completion 2006-12 Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT00174967
Dose-Response, Safety and Efficacy of Febuxostat in Subjects With Gout
Not yet reported Takeda 153 participants Est. completion 2001-07 Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT00175019
Allopurinol Versus Febuxostat in Subjects Completing the Phase 3 Trials C02-009 or C02-010
Not yet reported Takeda 1086 participants Est. completion 2007-02 Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT00430248
Efficacy and Safety of Oral Febuxostat in Participants With Gout
Not yet reported Takeda 2269 participants Est. completion 2008-03 258 sites Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT00821392
Phase III Trial of Febuxostat in Korea Gout Patients
Not yet reported SK Chemicals Co., Ltd. 181 participants Est. completion 2007-09Other conditions: GoutView official trial listing → -
Completed NCT NCT00995618
Study of Tranilast Alone or in Combination With Febuxostat in Patients With Hyperuricemia
Not yet reported Nuon Therapeutics, Inc. 24 participants Est. completion 2010-04 3 sites Stand-aloneOther conditions: Gout, HyperuricemiaView official trial listing → -
Completed NCT NCT01077284
Febuxostat Versus Allopurinol or Placebo in Patients With Hyperuricosuria and Calcium Oxalate Stones
Not yet reported Takeda 99 participants Est. completion 2011-11 28 sites Stand-aloneOther conditions: Hyperuricosuria, Kidney StonesView official trial listing → -
Completed NCT NCT01078389
Effect of Febuxostat on Joint Damage in Hyperuricemic Subjects With Early Gout
Not yet reported Takeda 314 participants Est. completion 2013-09 56 sites Stand-aloneOther conditions: Joint DamageView official trial listing → -
Completed NCT NCT01082640
Effect of Febuxostat on Renal Function in Patients With Gout and Moderate to Severe Renal Impairment
Not yet reported Takeda 96 participants Est. completion 2012-05 58 sites Stand-aloneOther conditions: Renal ImpairmentView official trial listing → -
Completed NCT NCT01101035
Cardiovascular Safety of Febuxostat and Allopurinol in Participants With Gout and Cardiovascular Comorbidities (CARES)
Not yet reported Takeda 6198 participants Est. completion 2017-07-18 203 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01112982
An Assessment of Chronic Synovial-Based Inflammation and Its Role With Serum Urate Levels.
Not yet reported University of South Florida 74 participants Est. completion 2014-12 1 siteOther conditions: GoutView official trial listing → -
Completed NCT NCT01328769
Febuxostat, Blood Pressure and the Intrarenal Renin-Angiotensin System (RAS)
Not yet reported Paul N. Hopkins 49 participants Est. completion 2014-01 1 siteOther conditions: HypertensionView official trial listing → -
Completed NCT NCT01350388
Effects of Febuxostat on Adipokines and Kidney Disease in Diabetic Chronic Kidney Disease
Not yet reported University of Utah 80 participants Est. completion 2013-12 1 siteChronic kidney disease Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01361646
Safety, Tolerability and Pharmacokinetic/Pharmacodynamic Characteristics of LC350189
Not yet reported LG Life Sciences 129 participants Est. completion 2013-01 1 siteOther conditions: Hyperuricemia, GoutView official trial listing → -
Completed NCT NCT01416402
Open Label Safety/Efficacy Study of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Gout Patients
Not yet reported Gilead Sciences 27 participants Est. completion 2011-10 1 siteOther conditions: Hyperuricemia, GoutView official trial listing → -
Completed NCT NCT01472692
Study of Febuxostat Effect on Blood Pressure in Patients With High Normal Blood Pressure
Not yet reported University of California, San Diego 47 participants Est. completion 2014-03 1 siteOther conditions: Prehypertension, Gout, Pulse Wave Velocity, Hypertension, 24 Hour Blood PressureView official trial listing → -
Completed NCT NCT01496469
Effect of Febuxostat on Blood Pressure
Not yet reported Takeda 121 participants Est. completion 2014-08 45 sites Stand-aloneOther conditions: HypertensionView official trial listing → -
Completed NCT NCT01510769
Combination Treatment Study in Subjects With Tophaceous Gout With Lesinurad and Febuxostat
Not yet reported Ardea Biosciences, Inc. 330 participants Est. completion 2014-06 124 sites Stand-aloneOther conditions: Tophaceous GoutView official trial listing → -
Terminated NCT NCT01549977
Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina
Not yet reported Takeda 1 participants Est. completion 2012-11 21 sites Stand-aloneOther conditions: AnginaView official trial listing → -
Completed NCT NCT01563432
Clinical Study to Evaluate the Pharmacokinetic Characteristics Between TMX-67 and Feburic® in Healthy Volunteers
Not yet reported SK Chemicals Co., Ltd. 30 participants Est. completion 2012-02 1 site Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT01654276
Effects of Hyperuricemia Reversal on Features of the Metabolic Syndrome
Not yet reported University of Texas Southwestern Medical Center 24 participants Est. completion 2015-03 1 site Stand-aloneOther conditions: GoutView official trial listing → -
Terminated NCT NCT01701622
The Blood Pressure Effects of Febuxostat in Patients Previously Treated With Allopurinol: A Pilot Study
Not yet reported University of Mississippi Medical Center 1 participants Est. completion 2011-10 1 site Stand-aloneOther conditions: Blood Pressure, GoutView official trial listing → -
Completed NCT NCT01712204
A Proof-of-Concept Study of AC-201 to Prevent Gout Flares
Not yet reported TWi Biotechnology, Inc. 82 participants Est. completion 2013-09 1 site Stand-aloneOther conditions: Gout FlaresView official trial listing → -
Completed NCT NCT01724528
Febuxostat for Tumor Lysis Syndrome Prevention in Hematologic Malignancies
Not yet reported Menarini Group 346 participants Est. completion 2013-10 Stand-aloneOther conditions: Tumor Lysis SyndromeView official trial listing → -
Completed NCT NCT01736514
A Study to Evaluate Safety and Efficacy of Oral Febuxostat in Patients With Gout
Not yet reported Astellas Pharma Taiwan, Inc. 109 participants Est. completion 2012-02 4 sites Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT01763996
The Influence of Febuxostat on Coronary Artery Endothelial Dysfunction in Participants With Chronic Stable Angina
Not yet reported Takeda 30 participants Est. completion 2015-04 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01808144
Lesinurad and Febuxostat Combination Extension Study in Gout
Not yet reported Ardea Biosciences, Inc. 196 participants Est. completion 2016-10-06 72 sites Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT01883167
RDEA3170 and Febuxostat Drug Interaction Study
Not yet reported Ardea Biosciences, Inc. 21 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01984749
Febuxostat for Cerebral and caRdiorenovascular Events prEvEntion stuDy
Not yet reported Freed Study Group 1000 participants 140 sites Stand-aloneOther conditions: HyperuricemiaView official trial listing → -
Completed NCT NCT02060552
Immune Molecular and Inflammatory Cytokines Dysfunction Analysis in Gout Patients With Different Urate Levels
Not yet reported Tongji Hospital 96 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Primary GoutView official trial listing → -
Completed NCT NCT02082769
Safety and Efficacy of Oral Febuxostat in Subjects With Gout
Not yet reported Xijing Hospital 504 participants Est. completion 2013-10 Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT02128490
Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout and Moderate Renal Impairment
Not yet reported Takeda 189 participants Est. completion 2015-10 89 sites Stand-aloneOther conditions: Gout, Moderate Renal ImpairmentView official trial listing → -
Completed NCT NCT02139046
Efficacy and Safety of Extended Release and Immediate Release Febuxostat in Participants With Gout
Not yet reported Takeda 1790 participants Est. completion 2015-11 192 sites Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT02246673
RDEA3170 and Febuxostat Combination Study in Gout Subjects
Not yet reported Ardea Biosciences, Inc. 64 participants Est. completion 2016-02 6 sites Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT02252835
Evaluate the PK, PD, and Safety of Arhalofenate in Combination With Febuxostat for Hyperuricemia in Patients With Gout
Not yet reported Gilead Sciences 32 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Gout, HyperuricemiaView official trial listing → -
Terminated NCT NCT02279342
the Effect of Febuxostat on Coronary Plaque Volume in Patients With Chronic Stable Angina and Hyperuricemia
Not yet reported Yokohama City University Medical Center 1 participants Est. completion 2017-03-31 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02287818
A Study of AC-201 Controlled-Release Tablet (CR Tablet) in Patients With Gout
Not yet reported TWi Biotechnology, Inc. 127 participants Est. completion 2016-10-27 1 site Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT02317861
A PD/Safety Study of RDEA3170 in Combination With Febuxostat for Treating Gout or Asymptomatic Hyperuricemia Patients
Not yet reported, Not yet reported AstraZeneca 110 participants Est. completion 2015-06 1 site Stand-aloneOther conditions: Gout and Asymptomatic HyperuricemiaView official trial listing → -
Completed NCT NCT02338128
The Cardiovascular Protective Effects of Febuxostat in Peritoneal Dialysis Patients
Shanghai 10th People's Hospital 50 participants Est. completion 2018-01 1 siteOther conditions: Disorders Associated With Peritoneal Dialysis, HyperuricemiaView official trial listing → -
Completed NCT NCT02338323
Compare the Renal Protective Effects of Febuxostat and Benzbromarone
Not yet reported Shanghai 10th People's Hospital 160 participants Est. completion 2018-12 1 site Stand-aloneChronic kidney disease Other conditions: Hyperuricemia, Abnormal Renal FunctionView official trial listing → -
Completed NCT NCT02344602
The Effect of Uric Acid Lowering in Type 1 Diabetes
Not yet reported University Health Network, Toronto 73 participants Est. completion 2015-09-22 1 site Stand-aloneOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02374164
Food Effect Study of Febuxostat XR in Healthy Participants
Not yet reported Takeda 36 participants Est. completion 2015-04 1 site Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT02382640
Effect of Antacid on Bioavailability of Febuxostat After Administration of a Febuxostat 80 mg Extended-Release Capsule
Not yet reported Takeda 36 participants Est. completion 2015-05 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02500641
Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout
Not yet reported Menarini International Operations Luxembourg SA 196 participants Est. completion 2017-05-10 26 sites Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT02504320
Phase 1, Febuxostat XR Relative Bioavailability Study
Not yet reported Takeda 78 participants Est. completion 2015-10 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02579096
CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat
Not yet reported VA Office of Research and Development 950 participants Est. completion 2021-04-15 23 sitesChronic kidney disease Other conditions: GoutView official trial listing → -
Completed NCT NCT02600780
Zurig (Febuxostat) 40mg Efficacy and Safety Trial
Not yet reported Getz Pharma 50 participants Est. completion 2015-03 1 site Stand-aloneOther conditions: HyperuricemiaView official trial listing → -
Completed NCT NCT02752633
Effect of Allopurinol and Febuxostat on Urinary 2,8-Dihydroxyadenine Excretion
Not yet reported Landspitali University Hospital 9 participants Est. completion 2015-05 1 site Stand-aloneOther conditions: Adenine Phosphoribosyltransferase DeficiencyView official trial listing → -
Completed NCT NCT02866214
Effect of Febuxostat on Endothelial Dysfunction in Hemodialysis Patients.
Not yet reported, Not yet reported Ain Shams University 57 participants Est. completion 2016-10 Stand-aloneOther conditions: Endothelial Dysfunction, Endstage Renal DiseaseView official trial listing → -
Status unknown NCT NCT02944214
Compare the Renal Protective Effects of Febuxostat and Benzbromarone in CKD Chinese Patients
Not yet reported Shanghai 10th People's Hospital 800 participants Est. completion 2019-12 1 site Stand-aloneChronic kidney disease Other conditions: Hyperuricemia, Abnormal Renal FunctionView official trial listing → -
Completed NCT NCT03118739
Intensive Uric Acid Lowering With Verinurad and Febuxostat in Patients With Albuminuria
Not yet reported AstraZeneca 60 participants Est. completion 2018-08-13 18 sites Stand-aloneType 2 diabetes Other conditions: Hyperuricemia, AlbuminuriaView official trial listing → -
Completed NCT NCT03131583
The Drug-Drug Interaction of SHR4640, Febuxostat and Colchicine in Patients With Gout
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 15 participants Est. completion 2018-01-29 1 site Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT03149939
Use of Febuxostat in Hyperuricemia Among Hemodialysis Patients
Not yet reported Benha University 19 participants Est. completion 2017-05-01Other conditions: Hyperuricemia, Hemodialysis ComplicationView official trial listing → -
Status unknown NCT NCT03200210
Lowering-hyperuricemia Treatment on Cardiovascular Outcomes in Peritoneal Dialysis Patients
Not yet reported Sun Yat-sen University 548 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: HyperuricemiaView official trial listing → -
Terminated NCT NCT03226899
A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment
Not yet reported Ironwood Pharmaceuticals, Inc. 242 participants Est. completion 2019-02-25 116 sitesChronic kidney disease Other conditions: GoutView official trial listing → -
Completed NCT NCT03316131
A Study to Assess the Effect of Intensive Uric Acid (UA) Lowering Therapy With RDEA3170, Febuxostat, Dapagliflozin on Urinary Excretion of UA
Not yet reported AstraZeneca 36 participants Est. completion 2018-07-19 2 sites Stand-aloneOther conditions: Asymptomatic HyperuricemiaView official trial listing → -
Status unknown NCT NCT03336203
The Impact of Urate-lowering Therapy on Kidney Function (IMPULsKF)
Not yet reported Medical Practice Prof D. Ivanov 2 participants Est. completion 2022-12-31 1 siteChronic kidney disease Other conditions: Gout, SUA Level (>8 mg/dL; 480 µmol/L)View official trial listing → -
Completed NCT NCT03372200
Febuxostat-Controlled, Double-Blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout
Not yet reported Mochida Pharmaceutical Company, Ltd. 203 participants Est. completion 2018-07-05 1 siteOther conditions: Hyperuricemia With or Without GoutView official trial listing → -
Completed NCT NCT03395977
Uric Acid Effects on Endothelium and Oxydative Stress
Not yet reported Erasme University Hospital 53 participants Est. completion 2020-02-27 1 site Stand-aloneOther conditions: Oxidative Stress, Endothelial Function, Cardiovascular System, HypertensionView official trial listing → -
Status unknown NCT NCT03425708
Effect of Hyperuricaemia on Chronic Renal Disease
Not yet reported The Affiliated Hospital of Xuzhou Medical University 400 participants Est. completion 2018-12-31 1 siteOther conditions: Hyperuricemia, Chronic Renal DiseaseView official trial listing → -
Status unknown NCT NCT03534037
Urate Lowering Therapies and Left Ventricular Diastolic Dysfunction
Not yet reported National Defense Medical Center, Taiwan 120 participants Est. completion 2021-12 1 site Stand-aloneMetabolic syndrome Other conditions: Hyperuricemia, Left Ventricular Diastolic DysfunctionView official trial listing → -
Terminated NCT NCT03605212
Febuxostat for Tumor Lysis Syndrome Prevention in Hematological Malignancies of Paediatric Patients and Adults
Not yet reported, Not yet reported Menarini Group 30 participants Est. completion 2018-07-25 17 sites Stand-aloneOther conditions: Tumor Lysis SyndromeView official trial listing → -
Status unknown NCT NCT03767322
Effect of Allopurinol or Febuxostat to Prevent Contrast Induced Acute Kidney Injury (CI-AKI)
Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 558 participants Est. completion 2019-12 1 siteOther conditions: Contrast-induced Nephropathy, Contrast-induced Acute Kidney InjuryView official trial listing → -
Completed NCT NCT03918551
Bioequivalence Study of Two Formulations of Febuxostat 120 mg Film-coated Tablets in Healthy Adult Volunteers After a Single Oral Dose Administration Under Fasting Conditions
Not yet reported Pharmtechnology LLC 50 participants Est. completion 2019-06-06 1 siteOther conditions: BioequivalenceView official trial listing → -
Status unknown NCT NCT04069325
Efficacy and Safety of Simiaowan in Prevention of Acute Flares in Chronic Gout Patients Initiating Febuxostat Therapy
Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 72 participants Est. completion 2020-07-28 1 site Stand-aloneOther conditions: Gout FlareView official trial listing → -
Withdrawn NCT NCT04072471
Post-Authorisation Safety Study of Lesinurad
AstraZeneca Est. completion 2023-06-30Other conditions: Gout, HyperuricemiaView official trial listing → -
Completed NCT NCT04155918
Phase 2a Study of AR882 Alone and in Combination With Febuxostat or Allopurinol in Gout Patients
Not yet reported Arthrosi Therapeutics 30 participants Est. completion 2020-09-03 1 site Stand-aloneOther conditions: Gout PatientsView official trial listing → -
Status unknown NCT NCT04157959
The Drug-Drug Interaction of SHR4640 and Febuxostat in Patients With Hyperuricemia
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 28 participants Est. completion 2020-06-30 1 site Stand-aloneOther conditions: HyperuricemiaView official trial listing → -
Status unknown NCT NCT04180982
A Safety and Efficacy Study of SHR4640 and Febuxostat in Subjects With Hyperuricemia
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 84 participants Est. completion 2020-08-30 Stand-aloneOther conditions: HyperuricemiaView official trial listing → -
Status unknown NCT NCT04213534
The Influence of Urate-lowering Therapy on Sperm Quality of Male Gouty Patients：A Prospective Cohort Study
Peking University Third Hospital 60 participants Est. completion 2023-12 1 siteOther conditions: GoutView official trial listing → -
Completed NCT NCT04347005
The Study is Designed to Evaluate Single Ascending Doses of AR882 in Healthy Adult Males
Not yet reported Arthrosi Therapeutics 64 participants Est. completion 2019-07-31 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT04352153
Role of Uralyt-U in Patients With Hyperuricemia
Not yet reported Ai Peng 102 participants Est. completion 2020-10-31 1 site Stand-aloneOther conditions: Uric Acid Stones, HyperuricemiaView official trial listing → -
Status unknown NCT NCT04398251
A Randomized Clinical Trail of The Effect of Postoperative Uric Acid Control on Stone Recurrence and Renal Function in Patients With Hyperuricemia of Urolithiasis.
Not yet reported Xuhui Central Hospital, Shanghai 100 participants Est. completion 2022-05-31 1 site Stand-aloneOther conditions: Hypouricemia, Renal, UrolithiasisView official trial listing → -
Terminated NCT NCT04697602
Low-dose Colchicine With or Without Stepwise Dose Titration of Febuxostat for Flare Prophylaxis in Gout
Not yet reported National Taiwan University Hospital 21 participants Est. completion 2023-08-23 1 site Stand-aloneOther conditions: GoutView official trial listing → -
Active, not recruiting NCT NCT04733079
Treat-to-target by Email During Urate-lowering Therapy in Gout
Not yet reported Assistance Publique - Hôpitaux de Paris 204 participants Est. completion 2026-12-31 2 sitesOther conditions: Gout, Inflammatory Rheumatism, Hyperuricemia, Posology AdjustmentView official trial listing → -
Status unknown NCT NCT04772352
Effects of Febuxostat for Lowering Uric Acid in NAFLD Patients With Gout
Not yet reported Ningbo No. 1 Hospital 200 participants Est. completion 2022-03-01 1 site Stand-aloneMASLDView official trial listing → -
Status unknown NCT NCT04799925
Hyperuricemia and Diabetic Nephropathy
Assiut University 200 participants Est. completion 2022-12-30Other conditions: Hyperuricemia, Diabetic NephropathiesView official trial listing → -
Completed NCT NCT04804111
Study of of URC102 to Assess the Efficacy and Safety in Gout Patients
Not yet reported JW Pharmaceutical 171 participants Est. completion 2020-11-29 2 sitesOther conditions: GoutView official trial listing → -
Completed NCT NCT04853160
Drug Use Study of Febuxostat After Recent Changes in the Prescribing Information
Takeda 24046 participants Est. completion 2021-01-05 1 siteCardiovascular disease Other conditions: GoutView official trial listing → -
Completed NCT NCT05007392
A Study to Evaluate Efficacy of Dotinurad and Febuxostat for the Treatment of Participants With Gout
Not yet reported Eisai Co., Ltd. 451 participants Est. completion 2023-06-14 30 sites Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT05264584
Renoprotective Effect of Febuxostat on Contrast Induced Acute Kidney Injury in Chronic Kidney Disease Patients Stage 3
Not yet reported Ain Shams University 120 participants Est. completion 2022-02-01 1 site Stand-aloneChronic kidney disease Other conditions: Contrast-induced NephropathyView official trial listing → -
Status unknown NCT NCT05324423
To Evaluate Drug Interactions Between XNW3009, Febuxostat, and Colchicine in Patients With Gout
Not yet reported The Affiliated Hospital of Qingdao University 20 participants Est. completion 2022-09-01 1 siteOther conditions: GoutView official trial listing → -
Status unknown NCT NCT05347498
A Trial of HR091506 Tablets in Treatment of Primary Gout With Hyperuricemia in Adults
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 90 participants Est. completion 2022-07-31 Stand-aloneOther conditions: Primary Gout With Hyperuricemia in AdultsView official trial listing → -
Completed NCT NCT05474560
Febuxostat Versus Allopurinol on Hepatic Steatosis in MAFLD Patients
Not yet reported Ain Shams University 90 participants Est. completion 2023-01-28 1 site Stand-aloneOther conditions: Non-Alcoholic Fatty Liver Disease, HyperuricemiaView official trial listing → -
Status unknown NCT NCT05513976
Clinical Study of SHR4640 Tablets Combined With Febuxostat Tablets in the Treatment of Primary Gout and Hyperuricemia
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 129 participants Est. completion 2023-09-20 Stand-aloneOther conditions: Primary Gout and HyperuricemiaView official trial listing → -
Active, not recruiting NCT NCT05574036
Comparative Study Between Febuxostat Versus Vitamin E in Non-alcoholic Steatohepatitis Patients With Hyperuricemia
Not yet reported Tanta University 70 participants Est. completion 2026-12-25 1 siteOther conditions: Non Alcoholic Steatohepatitis, HyperuricemiaView official trial listing → -
Completed NCT NCT05575297
A Drug-drug Interaction Study to Evaluate the Effect of Rifampicin and Febuxostat on the Pharmacokinetics of Methotrexate in Healthy Subjects
Not yet reported Seoul National University Hospital 12 participants Est. completion 2022-05-09 1 site Stand-aloneOther conditions: Drug InteractionView official trial listing → -
Completed NCT NCT05815901
A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patients
Not yet reported JW Pharmaceutical 612 participants Est. completion 2026-04-23 1 site Stand-aloneOther conditions: GoutView official trial listing → -
Completed NCT NCT06139393
Clinical Study of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 765 participants Est. completion 2025-09-04 1 site Stand-aloneOther conditions: Gout With Hyperuricemia in AdultsView official trial listing → -
Status unknown NCT NCT06233162
Febuxostat 80 mg Tablets Relative to Feburic® 80 mg Tablets
Not yet reported Bio-innova Co., Ltd 46 participants Est. completion 2024-10-15 Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Status unknown NCT NCT06414837
Clinical Trial of HR091506 Tablets in Treatment of Gout With Hyperuricemia in Adults
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 434 participants Est. completion 2026-06 Stand-aloneOther conditions: Gout With Hyperuricemia in AdultsView official trial listing → -
Completed NCT NCT06501534
A Dose Finding Study to Assess Efficacy and Safety of IBI128 in Chinese Gout Subjects
Not yet reported Innovent Biologics (Suzhou) Co. Ltd. 84 participants Est. completion 2025-01-09 1 siteOther conditions: Gout, HyperuricemiaView official trial listing → -
Not yet recruiting NCT NCT06525974
Clinical Study to Evaluate the Possible Efficacy and Safety of Febuxostat in Patients With Ulcerative Colitis Treated With Mesalamine
Not yet reported Tanta University 46 participants Est. completion 2026-12-30 Stand-aloneOther conditions: Ulcerative ColitisView official trial listing → -
Active, not recruiting NCT NCT06603142
Phase II/III Study of AR882 Capsules Compared to Febuxostat Tablets in Patients with Primary Gout and Hyperuricemia
Not yet reported, Not yet reported Guangzhou Ruianbo Pharmaceutical Technology Co., Ltd 636 participants Est. completion 2026-04 1 site Stand-aloneOther conditions: Primary Gout, HyperuricemiaView official trial listing → -
Not yet recruiting NCT NCT06653686
Study on the Efficacy and Safety of Thermotherapy in the Treatment of Refractory Gout
Not yet reported The First Hospital of Jilin University 128 participants Est. completion 2026-11 Stand-aloneOther conditions: Refractory GoutView official trial listing → -
Completed NCT NCT06995339
Comparative Clinical and Biochemical Study Evaluating the Effectiveness of Metformin Versus Febuxostat on Gouty Obese Non-Diabetic Patients
Not yet reported Mostafa Bahaa 60 participants Est. completion 2025-12-30 1 siteOther conditions: GoutView official trial listing → -
Completed NCT NCT06997952
Febuxostat Effect on Chronic Kidney Disease Progression And Carotid Intima-Media Thickness
Not yet reported Ain Shams University 50 participants Est. completion 2024-08-24 1 siteOther conditions: Carotid Intima- Media ThicknessView official trial listing → -
Not yet recruiting NCT NCT07181265
Drug-Drug Interaction of JMKX003142 With Amiodarone and Febuxostat in Healthy Subjects
Not yet reported Jemincare 48 participants Est. completion 2026-06-30 Stand-aloneOther conditions: Autosomal Dominant Polycystic Kidney Disease (ADPKD)View official trial listing → -
Not yet recruiting NCT NCT07323095
Evaluate the Efficacy and Safety of ABP-671 in Subjects With Chronic Kidney Disease and Hyperuricaemia
Not yet reported Atom Therapeutics Co., Ltd 80 participants Est. completion 2028-01-31 10 sites Stand-aloneChronic kidney diseaseView official trial listing → -
Not yet recruiting NCT NCT07326839
Orlistat and Weight Management for Uric Acid Control in Obese Gout: A RCT
Not yet reported XueMei Guo 120 participants Est. completion 2027-11-09 1 site Stand-aloneOther conditions: Gout, ObesityView official trial listing → -
Not yet recruiting NCT NCT07369622
HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness
Not yet reported Haiphong University of Medicine and Pharmacy 228 participants Est. completion 2028-12-30Other conditions: Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis, Gout and HyperuricemiaView official trial listing → -
Active, not recruiting NCT NCT07414394
Tigulixostat (IBI128) vs Febuxostat in Gout
Not yet reported Innovent Biologics Technology Limited (Shanghai R&D Center) 600 participants Est. completion 2027-10-30 1 site Stand-aloneOther conditions: GoutView official trial listing → -
Not yet recruiting NCT NCT07498647
Clinical Trial of BR2251 Tablets for Patients With Primary Gout and Hyperuricemia
Not yet reported BioRay Pharmaceutical Co., Ltd. 160 participants Est. completion 2026-11-30Other conditions: Gout and HyperuricemiaView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Febuxostat, Febuxostat Tablets
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.