About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Ezetimibe
- Company
- Taipei Medical University Hospital
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 40 recruiting
Efficacy results: Not yet reported
40 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 18, 2026
Find a Clinical Trial Near Me
See recruiting studies for Ezetimibe and check eligibility with the study team.
Trial details
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Recruiting NCT NCT04347434
Assessment of the Effects of Long-term Lipid-lowering Therapy in Patients With Primary STEMI or NSTEMI
Not yet reported Penza State University 300 participants Est. completion 2027-12-30 1 site Stand-aloneCardiovascular disease Other conditions: Myocardial Strain, Arterial Stiffness, Quality of LifeView official trial listing → -
Recruiting NCT NCT04499859
Low Dose Rosuvastatin Plus Ezetimibe Versus High-dose Rosuvastatin in AMI
Not yet reported Kiyuk Chang, MD,PhD 3548 participants Est. completion 2027-08-30 7 sites Stand-aloneCardiovascular disease Other conditions: Statin Adverse Reaction, HMG-CoA Reductase Inhibitor ToxicityView official trial listing → -
Recruiting NCT NCT04968509
Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis
Not yet reported Beijing Anzhen Hospital 160 participants Est. completion 2028-01 1 site Stand-aloneOther conditions: Aortic StenosisView official trial listing → -
Recruiting NCT NCT05103254
Bempedoic Acid Pregnancy Surveillance Program
Esperion Therapeutics, Inc. 20 participants Est. completion 2032-05 1 siteOther conditions: Pregnancy, HyperlipidemiasView official trial listing → -
Recruiting NCT NCT05365438
Atmeg (Atorvastatin and Omega-3 Combination) and Carotid Atherosclerosis in Patients With Type 2 Diabetes and Combined Dyslipidemia
Not yet reported Seoul National University Bundang Hospital 105 participants Est. completion 2026-12-31 1 siteType 2 diabetes Other conditions: Dyslipidemias, AtherosclerosisView official trial listing → -
Recruiting NCT NCT05641753
Cholesterol Lowering and Residual Risk in Diabetes, Type 1
Not yet reported NYU Langone Health 125 participants Est. completion 2027-07-31 4 sites Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Recruiting NCT NCT05705804
Effects of Pitavastatin or Combination of Pitavastatin and Ezetimibe on Glucose Metabolism Compared to AtoRvastatin in atheroscLerotic Cardiovascular Disease Patients With Metabolic Syndrome: The EZ-PEARL Randomized Trial
Not yet reported Yonsei University 250 participants Est. completion 2027-06-01 1 site Stand-aloneCardiovascular disease Other conditions: DyslipidemiasView official trial listing → -
Recruiting NCT NCT05765370
LDL Cholesterol TARGETs in OLDer Patients (Age≥75 Years) With ASCVD (TARGET OLD)
Not yet reported China National Center for Cardiovascular Diseases 4200 participants Est. completion 2026-12-24 1 site Stand-aloneCardiovascular disease Other conditions: Older Patients, LDL CholesterolView official trial listing → -
Recruiting NCT NCT05782777
Effect of High-intensity Statin With Ezetimibe COmbination theRapy Versus High-intensity sTatin Monotherapy After Percutaneous Coronary Intervention With Drug-eluting Stents; the ESCORT Trial
Not yet reported Yonsei University 4310 participants Est. completion 2027-12 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT05845424
High-intensity Statin and Ezetimibe Therapy for Asymptomatic Patients With Positive Coronary Calcium
Not yet reported Samsung Medical Center 6000 participants Est. completion 2030-06-30 1 site Stand-aloneMetabolic syndrome Other conditions: Coronary Artery Calcification, DyslipidemiasView official trial listing → -
Recruiting NCT NCT06186037
Clinical Comparison of Low-dose Rosuvastatin Plus Ezetimibe Combination Therapy and High-dose Rosuvastatin Monotherapy in Patients With Minimal to Intermediate Coronary Artery Disease Without Percutaneous Coronary Intervention
Not yet reported Saint Vincent's Hospital, Korea 6356 participants Est. completion 2029-02-28 1 site Stand-aloneCardiovascular disease Other conditions: Dyslipidemias, Primary PreventionView official trial listing → -
Recruiting NCT NCT06231966
Randomized Comparison of Efficacy and Safety of High-intensity Rosuvastatin/Ezetimibe Combination Versus Treat-to-target Rosuvastatin Monotherapy for Patients With Peripheral Artery or Polyvascular Disease (CARE-PVD Trial)
Not yet reported Yonsei University 2462 participants Est. completion 2029-05-06 1 site Stand-aloneOther conditions: Peripheral Artery Disease, Polyvascular DiseaseView official trial listing → -
Recruiting NCT NCT06293417
To Assess With Ezefeno Tab. in Patients With Dyslipidemia and T2DM
Not yet reported Korea University Anam Hospital 3958 participants Est. completion 2027-02-01 1 site Stand-aloneType 2 diabetes Other conditions: DyslipidemiasView official trial listing → -
Recruiting NCT NCT06314919
A Study to Evaluate the Efficacy and Safety of Fixed-Dose Combination of Pitavastatin/Ezetimib
Boryung Pharmaceutical Co., Ltd 8606 participants Est. completion 2026-06 1 siteOther conditions: Primary Hypercholesterolemia, Mixed DyslipidemiaView official trial listing → -
Recruiting NCT NCT06437574
Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer
Not yet reported Cedars-Sinai Medical Center 140 participants Est. completion 2028-05-31 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Recruiting NCT NCT06501443
LATAM LOWERS LDL-C
Not yet reported Novartis Pharmaceuticals 520 participants Est. completion 2026-11-29 11 sitesOther conditions: HypercholesterolaemiaView official trial listing → -
Recruiting NCT NCT06604117
Efficacy of Probucol Combined with Statins Treatment for Ischemic Stroke
Xuanwu Hospital, Beijing 200 participants Est. completion 2027-10 1 siteCardiovascular disease Other conditions: Atherosclerosis of Artery, Lipid Disorder, StatinView official trial listing → -
Recruiting NCT NCT06649240
Optimal Target Low-density Lipoprotein Cholesterol Level for Small Vessel Occlusion Stroke
Not yet reported Seoul National University Hospital 4016 participants Est. completion 2030-09 46 sites Stand-aloneCardiovascular disease Other conditions: Small Vessel Cerebrovascular Disease, Cholesterol, LDL, Secondary PreventionView official trial listing → -
Recruiting NCT NCT06686615
A Study of Bempedoic Acid in Combination With Ezetimibe and Either Rosuvastatin or Atorvastatin in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company 2000 participants Est. completion 2028-01-31 163 sitesOther conditions: Primary Hypercholesterolemiia, Mixed DyslipidemiaView official trial listing → -
Recruiting NCT NCT06722521
GUIDE-CAC: Statin-Ezetimibe Without Aspirin vs. Statin Monotherapy With Aspirin in High Coronary Calcification
Not yet reported Asan Medical Center 7435 participants Est. completion 2032-10-31 1 site Stand-aloneOther conditions: Primary Prevention, Vascular CalcificationView official trial listing → -
Recruiting NCT NCT06738758
Multicenter Real-World Cohort Study Evaluating the Impact of Early Intensive Lipid-Lowering Therapy on the Prognosis of Acute Coronary Syndrome Patients(ELITE-ACS)
Yun Dai Chen 6000 participants Est. completion 2027-12-31 1 siteOther conditions: Acute Coronary SyndromesView official trial listing → -
Recruiting NCT NCT06767345
Comparison of Moderate-Intensity Statin Plus Ezetimibe vs. High-Intensity Statin for Coronary Plaque Stabilization
Not yet reported Korea University Anam Hospital 408 participants Est. completion 2028-06-25 1 site Stand-aloneCardiovascular disease Other conditions: Atherosclerosis of Coronary Artery, Plaque, AtheroscleroticView official trial listing → -
Recruiting NCT NCT06767774
Comparison of Pitavastatin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus
Not yet reported Korea University Anam Hospital 2000 participants Est. completion 2030-01-31 1 site Stand-aloneCardiovascular disease Other conditions: Diabetes, StatinView official trial listing → -
Recruiting NCT NCT06784557
Effect of Ezetimibe on Gut Microbiota
Not yet reported Yonsei University 110 participants Est. completion 2025-10-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT06789432
Efficacy and Safety of Atorvastatin and Ezetimibe (10/10mg) Fixed Dose Combination Versus Atorvastatin (20mg) Monotherapy in Bangladeshi Population
Not yet reported Dr. Md. Alimur Reza 500 participants Est. completion 2025-12 1 site Stand-aloneOther conditions: Hyperlipidemia (E.G., Hypercholesterolemia)View official trial listing → -
Recruiting NCT NCT06858332
Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia
Novartis Pharmaceuticals 2382 participants Est. completion 2027-09-30 20 sitesCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT06896708
Effect of Intensive Lipid-Lowering Therapy on Coronary Atherosclerotic Plaque Progression in Young and Middle-Aged Patients With Chronic Coronary Syndrome
Not yet reported Liu yong 766 participants Est. completion 2028-03-01 7 sites Stand-aloneOther conditions: Chronic Coronary SyndromeView official trial listing → -
Recruiting NCT NCT06930092
RestoratIon of Myocardial Function by PeRcutaneous cOronary interVEntion in Patients With Ischemic CardioMyoPathy
Not yet reported Seoul National University Hospital 158 participants Est. completion 2029-04-30 1 siteOther conditions: Ischemic CardiomyopathyView official trial listing → -
Recruiting NCT NCT07036991
A Cohort Study Comparing PCSK9 Inhibitor Plus Statin With Statin Monotherapy for Carotid Artery Stenosis
Changhai Hospital 406 participants Est. completion 2027-06-01 1 siteOther conditions: Carotid Artery StenosisView official trial listing → -
Recruiting NCT NCT07083206
A Study to Evaluate the Effectiveness and Safety of Fixed-Dose Combination of Pitavastatin/ Ezetimibe
Ahn-Gook Pharmaceuticals Co.,Ltd 4500 participants Est. completion 2029-01 1 siteOther conditions: Hypercholesterolemia, DyslipidemiasView official trial listing → -
Recruiting NCT NCT07206472
A Study of Bempedoic Acid or Its Single-pill Combination Therapy With Ezetimibe in Patients With Primary Hypercholesterolaemia or Mixed Dyslipidaemia
Daiichi Sankyo 2120 participants Est. completion 2028-12-31 23 sitesOther conditions: Primary Hypercholesterolaemia, Mixed DyslipidemiaView official trial listing → -
Recruiting NCT NCT07208006
Very Early PCSK9 Inhibition for Acute Myocardial Infarction
Not yet reported Shanghai Zhongshan Hospital 1518 participants Est. completion 2028-10-31 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT07307989
Early Statin-Ezetimibe Combination vs. Statin Monotherapy in Stroke With Atherosclerosis
Not yet reported Chang Gung Memorial Hospital 300 participants Est. completion 2029-07-31 1 site Stand-aloneCardiovascular disease Other conditions: HypercholesteremiaView official trial listing → -
Recruiting NCT NCT07359105
Moderate-intensity Statin vs. Individualized LDL-C Target-based Therapy in Older Adults With Type 2 Diabetes (iTARGET-Elderly Study)
Not yet reported Sin Gon Kim 2186 participants Est. completion 2029-12-31 2 sites Stand-aloneOther conditions: Dyslipidemia Associated With Type II Diabetes MellitusView official trial listing → -
Recruiting NCT NCT07447648
Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)
Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) 52 participants Est. completion 2029-02 13 sitesOther conditions: Homozygous Familial Hypercholesterolemia (HoFH), Coronary Computed Tomography AngiographyView official trial listing → -
Recruiting NCT NCT07523971
Efficacy and Safety of Pitavastatin/Ezetimibe in Dyslipidemia Patients With Metabolic Syndrome: An Observational Study
JW Pharmaceutical 10000 participants Est. completion 2027-06 1 siteOther conditions: DyslipidemiasView official trial listing → -
Recruiting NCT NCT07524101
Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD
Not yet reported Yonsei University 1952 participants Est. completion 2031-01-22 1 site Stand-aloneCardiovascular disease Other conditions: Renal Insufficiency, Atherosclerosis, Dyslipidemia, HypercholesterolemiaView official trial listing → -
Recruiting NCT NCT07679828
Polypills Approach for Multiple Cardiovascular Risk Factors
Not yet reported China Medical University, China 8252 participants Est. completion 2030-03-01 15 sites Stand-aloneOther conditions: Hypertension, Dyslipidemia, DiabetesView official trial listing → -
Recruiting NCT NCT07704918
Aggressive Lipid Lowering Therapy in ICI-Treated Melanoma
Not yet reported University of Colorado, Denver 40 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: MelanomaView official trial listing → -
Recruiting NCT NCT07824323
Early Triple Lipid-Lowering Therapy With Bempedoic Acid After Acute Coronary Syndrome
Not yet reported Taipei Medical University Hospital 400 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Acute Coronary Syndromes, DyslipidemiaView official trial listing → -
Completed NCT NCT00045812
SCH-58235 (Ezetimibe) to Treat Homozygous Sitosterolemia
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 5 participants Est. completion 2004-04 1 siteOther conditions: LipoidosisView official trial listing → -
Completed NCT NCT00079638
Comparative Efficacy Evaluation of Lipids When Treated With Niaspan & Statin or Other Lipid-Modifying Therapies-COMPELL
Not yet reported Kos Pharmaceuticals 300 participants Est. completion 2005-05Cardiovascular disease Other conditions: Dyslipidemia, Coronary Heart Disease, Atherosclerosis, DiabetesView official trial listing → -
Completed NCT NCT00090168
Cholesterol Lowering Level of MK0653A+Simvastatin in Patients With Hypercholesterolemia and Atherosclerotic or Coronary Vascular Disease (0653A-806)(COMPLETED)
Not yet reported Organon and Co 435 participants Est. completion 2004-11-10Other conditions: Hypercholesterolemia, Atherosclerotic Disease, Coronary DiseaseView official trial listing → -
Completed NCT NCT00090298
Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Drugs in Patients With Elevated Cholesterol Levels (0653A-058)
Not yet reported Organon and Co 2815 participants Est. completion 2004-12Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00092560
Two Investigational Drugs in Patients With Mixed Hyperlipidemia (0653-036)
Not yet reported Organon and Co 587 participants Est. completion 2003-12Other conditions: Hypercholesterolemia, HypertriglyceridemiaView official trial listing → -
Completed NCT NCT00092573
Study of Ezetimibe and Fenofibrate in Patients With Mixed Hyperlipidemia (0653-036)(COMPLETED)
Not yet reported Organon and Co 576 participants Est. completion 2004-11Other conditions: Hypercholesterolemia, HypertriglyceridemiaView official trial listing → -
Completed NCT NCT00092586
Study of an Approved Drug With a Statin (a Medication That Lowers Cholesterol Levels) as Compared to Statin Therapy Alone in Patients With High Cholesterol (0653-040)
Not yet reported Organon and Co 2904 participants Est. completion 2003-10Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00092599
Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-801)
Not yet reported Organon and Co 410 participants Est. completion 2004-07Other conditions: Hypercholesterolemia, Coronary DiseaseView official trial listing → -
Completed NCT NCT00092612
Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-802)(COMPLETED)
Not yet reported Organon and Co 372 participants Est. completion 2004-06Other conditions: Hypercholesterolemia, Coronary DiseaseView official trial listing → -
Completed NCT NCT00092625
Co-administration Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-803)
Not yet reported Organon and Co 442 participants Est. completion 2004-08Other conditions: Hypercholesterolemia, Coronary DiseaseView official trial listing → -
Completed NCT NCT00092638
An Investigational Drug Study in Patients With Elevated Cholesterol and Coronary Heart Disease (0653-804)(COMPLETED)
Not yet reported Organon and Co 450 participants Est. completion 2004-08Other conditions: Hypercholesterolemia, Coronary DiseaseView official trial listing → -
Completed NCT NCT00092651
A Study of MK0653A (Ezetimibe (+) Simvastatin) in Patients With Hypercholesterolemia (0653A-038)
Not yet reported Organon and Co 1398 participants Est. completion 2003-06Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00092664
An Extension Study of An Investigational Drug in Patients With Hypercholesterolemia (0653A-038)(COMPLETED)
Not yet reported Organon and Co 1104 participants Est. completion 2003-09Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00092677
An Investigational Drug on Clinical Outcomes in Patients With Aortic Stenosis (Narrowing of the Major Blood Vessel of the Heart)(MK-0653A-043 AM4)(COMPLETED)
Not yet reported Organon and Co 1873 participants Est. completion 2008-04 Stand-aloneOther conditions: Aortic StenosisView official trial listing → -
Completed NCT NCT00092690
MK0653A (Ezetimibe (+) Simvastatin) Compared to an Approved Drug (Atorvastatin) for the Treatment of High Cholesterol (0653A-051)(COMPLETED)
Not yet reported Organon and Co 1902 participants Est. completion 2004-03Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00092716
Comparing an Investigational Medication Versus an Approved Medication in Reducing Cholesterol Levels (0653-025)
Not yet reported Organon and Co 655 participants Est. completion 2003-04Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00092807
Sitosterolemia Extension Study (0653-003)(COMPLETED)
Not yet reported Organon and Co 37 participants Est. completion 2004-11-30Other conditions: Lipid Metabolism, Inborn Errors, Heart DiseaseView official trial listing → -
Completed NCT NCT00092820
Sitosterolemia Extension Study (0653-004)(COMPLETED)
Not yet reported Organon and Co 58 participants Est. completion 2004-11-30Other conditions: Lipid Metabolism, Inborn Errors, Heart DiseaseView official trial listing → -
Terminated NCT NCT00092833
Investigational Drug in Patients With Hypercholesterolemia or in Patients With Sitosterolemia (0653-026)(COMPLETED)
Not yet reported Organon and Co 49 participants Est. completion 2005-05 Stand-aloneOther conditions: Hypercholesterolemia, Familial, Lipid Metabolism, Inborn ErrorsView official trial listing → -
Completed NCT NCT00092898
An Investigational Drug Study to Lower Non-Cholesterol Sterol Levels Associated With Sitosterolemia (0653-062)(COMPLETED)
Not yet reported Organon and Co 30 participants Est. completion 2005-10Other conditions: Lipid Metabolism, Inborn Errors, Heart DiseaseView official trial listing → -
Completed NCT NCT00093899
A Study to Evaluate an Investigational Drug in Patients With Mixed Hyperlipidemia (0653A-071)(COMPLETED)
Not yet reported Organon and Co 611 participants Est. completion 2005-09Other conditions: Hyperlipidemia, Hypercholesterolemia, HypertriglyceridemiaView official trial listing → -
Completed NCT NCT00099684
Safety, Effectiveness, and Tolerability of Ezetimibe Combined With Statins for the Treatment of High Cholesterol in HIV Infected Adults
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 44 participants Est. completion 2007-05 42 sitesOther conditions: HIV InfectionsView official trial listing → -
Completed NCT NCT00099996
Higher-Dose Ezetimibe to Treat Homozygous Sitosterolemia
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 3 participants Est. completion 2005-12 1 siteOther conditions: Heart Diseases, Metabolism, Inborn ErrorsView official trial listing → -
Completed NCT NCT00101439
A Study to Evaluate the Effects of Ezetimibe (MK-0653) on the Postprandial (Following a Meal) Lipoprotein Response in Participants With Primary Hypercholesterolemia (High Cholesterol) (MK-0653-072)(COMPLETED)
Not yet reported Organon and Co 58 participants Est. completion 2006-11-08 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00110435
A Multicenter Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Products in Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia (MK-0653A-077)
Not yet reported Organon and Co 1229 participants Est. completion 2005-12Type 2 diabetes Other conditions: HypercholesterolemiaView official trial listing → -
Terminated NCT NCT00120289
Niacin Plus Statin to Prevent Vascular Events
Not yet reported Axio Research. LLC 3414 participants Est. completion 2012-12 91 sites Stand-aloneCardiovascular disease Other conditions: Heart Diseases, Cerebrovascular Accident, Coronary Disease, AtherosclerosisView official trial listing → -
Completed NCT NCT00125593
Study of Heart and Renal Protection
Not yet reported University of Oxford 9438 participants Est. completion 2010-08 1 siteOther conditions: Kidney Disease, ChronicView official trial listing → -
Completed NCT NCT00127218
High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly
Not yet reported Johns Hopkins University 145 participants Est. completion 2008-12 1 siteCardiovascular disease Other conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT00129402
Effects of Ezetimibe With Simvastatin in the Therapy of Adolescents With HeFH (Study P02579)
Not yet reported Organon and Co 248 participants Est. completion 2007-06 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00132717
A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)
Not yet reported Organon and Co 450 participants Est. completion 2007-06-01Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00157482
Ezetimibe and Simvastatin in Dyslipidemia of Diabetes
Not yet reported Mario Negri Institute for Pharmacological Research 108 participants Est. completion 2006-12 4 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00157911
A Study to Evaluate Ezetimibe in Korean Patients With Primary Hypercholesterolemia (0653-042)
Not yet reported Organon and Co 136 participants Est. completion 2003-12Other conditions: HypercholerolemiaView official trial listing → -
Completed NCT NCT00157924
Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)
Not yet reported Organon and Co 190 participants Est. completion 2007-09 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00166504
Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)
Not yet reported Organon and Co 203 participants Est. completion 2007-10 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00166530
EASEGO Study: Doubling of Atorvastatin/Simvastatin or INEGY in Patients With Hypercholesterolemia and Coronary Artery Disease(CAD)(0653A-089)
Not yet reported Organon and Co 367 participants Est. completion 2007-02 Stand-aloneOther conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT00171288
Efficacy and Safety Study of Fluvastatin and Ezetimibe Combined Versus Fluvastatin Alone
Not yet reported Novartis 83 participants Est. completion 2005-08 1 siteOther conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT00185107
Effect of Combination Therapy With Two Drugs (Colesevelam and Ezetimibe) in Patients With High Cholesterol
Not yet reported Daiichi Sankyo 45 participants Est. completion 2005-10 7 sitesOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00189085
Effects of Ezetimibe on Postprandial Hyperlipidemia and Endothelial Function
Not yet reported UMC Utrecht 20 participants Est. completion 2005-07 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT00195793
A 16 Week Comparative Study of Fenofibrate Versus Ezetimibe as Add-on Therapy to Atorvastatin
Not yet reported Abbott 174 participantsOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT00202878
IMPROVE-IT: Examining Outcomes in Subjects With Acute Coronary Syndrome: Vytorin (Ezetimibe/Simvastatin) vs Simvastatin (P04103)
Not yet reported Organon and Co 18144 participants Est. completion 2014-09-18 Stand-aloneCardiovascular disease Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00202904
Effectiveness and Safety of Ezetimibe Added to Atorvastatin in Patients With High Cholesterol and Coronary Heart Disease (Study P03740)
Not yet reported Organon and Co 81 participants Est. completion 2006-10 Stand-aloneOther conditions: Hypercholesterolemia, Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00203476
A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction
Not yet reported Tuscaloosa Research & Education Advancement Corporation 30 participants Est. completion 2008-01 1 siteOther conditions: Hyperlipidemia, HypercholesterolemiaView official trial listing → -
Terminated NCT NCT00267267
A Clinical Trial Comparing Torcetrapib/Atorvastatin to Ezetimibe/Simvastatin In Subjects With A Cholesterol Disorder.
Not yet reported Pfizer 1784 participants Est. completion 2007-01 123 sitesOther conditions: Hyperlipidemia, DyslipidemiaView official trial listing → -
Completed NCT NCT00268697
Efficacy of Lapaquistat Acetate Alone and With Ezetimibe in Subjects With Primary Dyslipidemia.
Not yet reported Takeda 1267 participants Est. completion 2007-01 9 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00271817
To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED)
Not yet reported Organon and Co 1220 participants Est. completion 2008-02Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00276458
To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 20 mg (0653-079)(COMPLETED)
Not yet reported Organon and Co 196 participants Est. completion 2008-01 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00276484
To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 40 mg (0653-090)
Not yet reported Organon and Co 579 participants Est. completion 2008-03 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00299884
Atorvastatin Versus Ezetimibe and Fenofibrate as a Lipid-lowering Strategy
Queen's University 45 participants Est. completion 2006-07 1 siteOther conditions: Dyslipidemia, Vascular DiseaseView official trial listing → -
Completed NCT NCT00317993
LDL Receptor Under Ezetimibe and Simvastatin
Not yet reported University of Cologne 60 participants Est. completion 2004-07 1 siteOther conditions: Healthy MenView official trial listing → -
Completed NCT NCT00319449
Adding Ezetimibe Tablet to Ongoing Treatment With Atorvastatin in Subjects With High Cholesterol and Multiple Coronary Heart Disease Risk Factors (Study P04060)(COMPLETED)
Not yet reported Organon and Co 22 participants Est. completion 2006-10 Stand-aloneOther conditions: Hypercholesterolemia, Coronary ArteriosclerosisView official trial listing → -
Completed NCT NCT00328523
TWICE (Ezetimibe Together With Any Statin Cholesterol Enhancement)(0653-060)
Not yet reported Organon and Co 1496 participants Est. completion 2006-01Other conditions: Hypercholesterolaemia, HyperlipidaemiaView official trial listing → -
Completed NCT NCT00349284
A Controlled-Study of Fenofibrate 145 mg and Ezetimibe 10 mg in Type IIb Dyslipidemic Patients With Features of the Metabolic Syndrome
Not yet reported Solvay Pharmaceuticals 181 participants 43 sitesOther conditions: Hyperlipidemia CombinedView official trial listing → -
Completed NCT NCT00359281
Pharmacokinetic Drug Interactions of AEGR-733 on Lipid-lowering Agents
Not yet reported Aegerion Pharmaceuticals, Inc. 125 participants Est. completion 2007-11 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT00376246
Effect of Ezetimibe on Flow-mediated Brachial Artery Reactivity in Healthy Subjects
Not yet reported University of California, San Diego 28 participants Est. completion 2008-04Other conditions: Endothelial DysfunctionView official trial listing → -
Completed NCT NCT00385658
Efficacy of Fluvastatin and Fenofibrate in Comparison to Simvastatin and Ezetimibe in Patients With Metabolic Syndrome
Not yet reported Novartis 75 participants Est. completion 2007-03 2 sitesOther conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT00395473
Ezetimibe Added to Statin Therapy (EASY) Study (0653-087)(COMPLETED)
Not yet reported Organon and Co 141 participants Est. completion 2005-11Other conditions: HypercholesterolemiaView official trial listing → -
Terminated NCT NCT00395603
Vytorin Treating Uncontrolled Lipids (VyTUL) Study (0653A-122)
Not yet reported Organon and Co 550 participants Est. completion 2007-06Cardiovascular disease Other conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT00397657
Comparative Study of the Effect of Ezetimibe Versus Extended-Release Niacin on Atherosclerosis
Not yet reported Walter Reed Army Medical Center 400 participants Est. completion 2009-10 2 sitesOther conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT00405067
The Safety & Efficacy of Combination BMS-201038 (AEGR-733) & Ezetimibe vs. Monotherapy in Moderate Hypercholesterolemia
Not yet reported Aegerion Pharmaceuticals, Inc. 60 participants Est. completion 2007-01 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00408057
Guidelines Based Undertaking for Improvement in Dyslipidemia Related Events (GUIDE )
Canadian Heart Research Centre 2500 participants Est. completion 2007-11 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00409773
Ezetimibe/Simvastatin in Patients With Metabolic Syndrome (0653A-107)(COMPLETED)
Not yet reported Organon and Co 1143 participants Est. completion 2008-07Metabolic syndrome Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00413972
Effects of Vytorin Versus Placebo in Subjects With Primary Hypercholesterolemia (Study P04420)
Not yet reported Organon and Co 392 participants Est. completion 2006-11 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00418834
Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112)
Not yet reported Organon and Co 1053 participants Est. completion 2008-10Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00423488
Ezetimibe and Simvastatin in Primary Hypercholesterolemia, Diabetes Mellitus Type 2, and Coronary Heart Disease (COMPLETED)
Not yet reported Organon and Co 93 participants Est. completion 2007-02-16 Stand-aloneType 2 diabetes Other conditions: Hypercholesterolemia, Coronary DiseaseView official trial listing → -
Completed NCT NCT00423579
The Effects of Ezetimibe/Simvastatin 10/20 mg Versus Simvastatin 40 mg in High Cholesterol and Coronary Heart Disease Study (P04039AM2)(COMPLETED)
Not yet reported Organon and Co 120 participants Est. completion 2008-03-01 Stand-aloneOther conditions: Hypercholesterolemia, Coronary DiseaseView official trial listing → -
Status unknown NCT NCT00433823
A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis
Not yet reported Abant Izzet Baysal University Est. completion 2008-01 1 siteOther conditions: Coronary Heart Disease, Diabetes Mellitus, Non-Coronary Atherosclerotic Disease, HypercholesterolemiaView official trial listing → -
Completed NCT NCT00440154
A Study Evaluating the Safety and Efficacy of AVE5530 (4 Weeks) in Patients With Mild to Moderate Hypercholesterolemia
Not yet reported Sanofi 206 participants Est. completion 2007-10 6 sitesOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00442897
Vytorin (10/20 Or 10/40) Compared to Atorvastatin (10 mg or 20 mg) in Patients With Coronary Artery Disease (0653A-126)(COMPLETED)
Not yet reported Organon and Co 229 participants Est. completion 2008-10 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00449410
Silent Cerebrovascular Lesion and Cognitive Decline Prevention by Cholesterol Lowering in Elderly AF Patients
Not yet reported Radboud University Medical Center 35 participants Est. completion 2006-10 1 siteOther conditions: Atrial Fibrillation, Neuropsychology, Magnetic Resonance Imaging, Inflammation, HemostasisView official trial listing → -
Completed NCT NCT00457275
Observational Study to Evaluate LDL-C Lowering Effect of Ezetimibe (0653-070)
Not yet reported Organon and Co 440 participants Est. completion 2005-11Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00461630
Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE
Not yet reported University of Oxford 25673 participants Est. completion 2012-10 1 site Stand-aloneCardiovascular disease Other conditions: Peripheral Arterial Disease, Diabetes Mellitus, Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00461968
Comparison of Efficacy and Safety of Ezetimibe or Statin Monotherapy to Co-Administration of Both
Not yet reported University of Texas Southwestern Medical Center 240 participants Est. completion 2007-04 1 siteOther conditions: Cholesterol, LDLView official trial listing → -
Completed NCT NCT00462748
A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)
Not yet reported Organon and Co 786 participants Est. completion 2008-06 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00466401
Effect of Ezetimibe on Platelet Aggregation and LDL Tendency to Peroxidation
Not yet reported Ziv Hospital 20 participants Est. completion 2007-08 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00474123
Antiplatelet and Anti-inflammatory Effects of Statins and Ezetimibe
Not yet reported University of Sao Paulo 78 participants Est. completion 2009-08 1 siteOther conditions: Stable AnginaView official trial listing → -
Status unknown NCT NCT00475826
Evaluation of Chylomicrons Metabolism in Sub-Clinical Atherosclerosis in Patients Whit Heterozigous Familial Hypercholesterolemia (FH) Treated With Statin Plus Ezetimibe
Not yet reported University of Sao Paulo 1 siteOther conditions: Heterozigous Familial HypercholesterolemiaView official trial listing → -
Completed NCT NCT00477204
Clinical Trial of Zocor (Simvastatin) and Vytorin (Ezetimibe/Simvastatin) in Adolescents With Type 1 Diabetes
Not yet reported University of Colorado, Denver 9 participants Est. completion 2010-08 1 siteOther conditions: Type 1 Diabetes Mellitus, DyslipidemiaView official trial listing → -
Completed NCT NCT00479713
A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk (0653A-809)(COMPLETED)
Not yet reported Organon and Co 618 participants Est. completion 2008-03-01 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00481351
Effects of Statin and Ezetimibe Association on Kinetics of Artificial Chilomicrons
Not yet reported University of Sao Paulo 25 participants Est. completion 2010-01 Stand-aloneOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00485121
Effects of Ezetimibe Add-On to Statin Therapy on Adipokine Production in Obese and Metabolic Syndrome Patients With Atherosclerosis
Not yet reported Canadian Collaborative Research Network 50 participants Est. completion 2009-04 1 siteMetabolic syndromeCardiovascular disease Other conditions: ObesityView official trial listing → -
Completed NCT NCT00496730
A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea (0653A-129)(COMPLETED)
Not yet reported Organon and Co 256 participants Est. completion 2008-08 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00525824
12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe
Not yet reported AstraZeneca 1743 participants Est. completion 2008-09 9 sitesOther conditions: Hypercholesterolemia, Coronary Heart Disease, AtherosclerosisView official trial listing → -
Completed NCT NCT00535405
A Study to Assess the Cholesterol Lowering Effect of Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Elderly Patients With High Cholesterol at High or Moderately High Risk for Coronary Heart Disease (0653A-128)
Not yet reported Organon and Co 1289 participants Est. completion 2009-03 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00541697
Eze/Simva Switch Study in Diabetics (0653A-807)
Not yet reported Organon and Co 648 participants Est. completion 2005-10-14Type 2 diabetesView official trial listing → -
Terminated NCT NCT00548145
The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's Disease
Not yet reported Osaka University 38 participants Est. completion 2012-03 1 siteOther conditions: Alzheimer Disease, HypercholesterolemiaView official trial listing → -
Completed NCT NCT00551447
A Study Comparing Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Patients at Risk for Heart Disease (0653-023)(COMPLETED)
Not yet reported Organon and Co 616 participants Est. completion 2003-03Other conditions: Coronary DiseaseView official trial listing → -
Completed NCT NCT00551876
Study Evaluating the Efficacy and Safety of Simvastatin Alone Compared With Simvastatin Plus Ezetimibe in Type 2 Diabetic Patients (0653-021)(COMPLETED)
Not yet reported Organon and Co 214 participants Est. completion 2003-01Type 2 diabetesView official trial listing → -
Completed NCT NCT00552097
Effect of Ezetimibe Plus Simvastatin Versus Simvastatin Alone on Atherosclerosis in the Carotid Artery (ENHANCE)(P02578)
Not yet reported Organon and Co 720 participants Est. completion 2006-04-25 Stand-aloneOther conditions: Atherosclerosis, Hypercholesterolemia, Hyperlipoproteinemia Type IIView official trial listing → -
Completed NCT NCT00559962
Evaluate Low Doses of AEGR-733 on Hepatic Fat Accumulation by MRS
Not yet reported Aegerion Pharmaceuticals, Inc. 260 participants Est. completion 2008-11 15 sitesOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT00560170
Vascular Effects of Ezetimibe/Simvastatin and Simvastatin on Atherosclerosis
Not yet reported National Cheng-Kung University Hospital 40 participants Est. completion 2008-02 1 siteOther conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT00566267
A Randomized, Double-Blinded Study of Simvastatin 20 mg/Day Versus Vytorin 10/20 in Subjects With Lipid Profiles Not Meeting Current NCEP Guidelines, Following a Low-Carbohydrate Diet
Not yet reported, Not yet reported Merck Sharp & Dohme LLC 58 participants Est. completion 2007-11 Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT00587678
Comprehensive Magnetic Resonance of Peripheral Arterial Disease
Not yet reported University of Virginia 85 participants Est. completion 2009-10 1 site Stand-aloneOther conditions: Peripheral Artery DiseaseView official trial listing → -
Completed NCT NCT00621101
Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects
Not yet reported University Medicine Greifswald 24 participants Est. completion 2007-06 1 site Stand-aloneOther conditions: Pharmacokinetics, Drug Interactions, Hypercholesterolemia, ImmunosuppressionView official trial listing → -
Completed NCT NCT00621699
Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects
Not yet reported University Medicine Greifswald 24 participants Est. completion 2007-11 1 site Stand-aloneOther conditions: Pharmacokinetics, Drug Interactions, Hypercholesterolemia, ImmunosuppressionView official trial listing → -
Withdrawn NCT NCT00634140
The Influence of Ezetimibe on Gallbladder Function
Not yet reported Indiana University Est. completion 2009-08 1 site Stand-aloneOther conditions: Chronic Acalculous CholecystitisView official trial listing → -
Completed NCT NCT00639158
Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood
Not yet reported Abbott 543 participants 118 sitesOther conditions: Dyslipidemias, Coronary Heart Disease, Combined (Atherogenic) Dyslipidemia, Mixed DyslipidemiaView official trial listing → -
Completed NCT NCT00650663
Ezetimibe Plus Simvastatin Versus Simvastatin Alone in African-American Subjects With Primary Hypercholesterolemia (P03377)
Not yet reported Organon and Co 247 participants Est. completion 2004-09-01 Stand-aloneOther conditions: Hypercholesterolemia, AtherosclerosisView official trial listing → -
Completed NCT NCT00650689
Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With Primary Hypercholesterolemia and Coronary Heart Disease (P03396)
Not yet reported Organon and Co 122 participants Est. completion 2004-12 Stand-aloneCardiovascular disease Other conditions: Hypercholesterolemia, AtherosclerosisView official trial listing → -
Completed NCT NCT00650819
Comparison of Ezetimibe Plus Simvastatin Versus Ezetimibe or Simvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03757)(COMPLETED)
Not yet reported Organon and Co 240 participants Est. completion 2005-02-01 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Terminated NCT NCT00651014
Ezetimibe Plus Simvastatin Versus Simvastatin in Patients With Hypercholesterolemia and Coronary Risk Factors (P03405)
Not yet reported Organon and Co 82 participants Est. completion 2006-06 Stand-aloneOther conditions: Hypercholesterolemia, AtherosclerosisView official trial listing → -
Completed NCT NCT00651144
Assessment of Potential Interaction Between Ezetimibe and Rosuvastatin in Healthy Subjects With High Cholesterol (P03317)
Not yet reported Organon and Co 40 participants Est. completion 2003-05 Stand-aloneOther conditions: Hypercholesterolemia, AtherosclerosisView official trial listing → -
Completed NCT NCT00651274
Comparison of Co-administration of Ezetimibe Plus Simvastatin Versus Simvastatin Alone in Primary Hypercholesterolemia (P03476)
Not yet reported Organon and Co 144 participants Est. completion 2004-08-01 Stand-aloneOther conditions: Atherosclerosis, Hypercholesterolemia, Coronary Heart DiseaseView official trial listing → -
Terminated NCT NCT00651378
Switching to Rosuvastatin Versus Adding Ezetimibe to Atorvastatin Versus Doubling the Dose of Atorvastatin in Patients With Hypercholesterolemia and Risk Factors (P03708)
Not yet reported Organon and Co 87 participants Est. completion 2005-06-01Cardiovascular disease Other conditions: Hypercholesterolemia, AtherosclerosisView official trial listing → -
Terminated NCT NCT00651391
Effect of Ezetimibe Plus Simvastatin on Flow-Mediated Brachial Artery Vasoactivity in Subjects With Primary Hypercholesterolemia (Study P03336)
Not yet reported Organon and Co 28 participants Est. completion 2004-09-01 Stand-aloneOther conditions: Hypercholesterolemia, AtherosclerosisView official trial listing → -
Completed NCT NCT00651404
Ezetimibe Plus Atorvastatin Versus Atorvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03406)
Not yet reported Organon and Co 137 participants Est. completion 2004-12 Stand-aloneOther conditions: Hypercholesterolemia, AtherosclerosisView official trial listing → -
Completed NCT NCT00651560
Vytorin As Strategy To Reduce Dislipidemia In Adults (0653A-148)
Not yet reported Organon and Co 167 participants Est. completion 2005-12-23Other conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT00651963
Open Label Study Evaluating The Use Of Combination Therapy Of Ezetimibe And Statins In Patients With Dyslipidemia In Colombia (0653-141)(COMPLETED)
Not yet reported Organon and Co 80 participants Est. completion 2005-03Other conditions: Lipid Metabolism DisorderView official trial listing → -
Completed NCT NCT00652301
A Research Study to Evaluate MK0653 (Ezetimibe) and Simvastatin, Given Together and Alone, on Intestinal Absorption of Cholesterol (0653-050)(COMPLETED)
Not yet reported Organon and Co 40 participants Est. completion 2004-04 Stand-aloneOther conditions: CholesterolView official trial listing → -
Completed NCT NCT00652327
Comparison of Ezetimibe Added to Ongoing Statin Therapy Versus Doubling the Dose of Statin in the Treatment of Hypercholesterolemia (P04355)
Not yet reported Organon and Co 83 participants Est. completion 2007-07 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00652431
Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2)
Not yet reported Organon and Co 18 participants Est. completion 2007-07 Stand-aloneOther conditions: Hypercholesterolemia, HyperlipidemiaView official trial listing → -
Completed NCT NCT00652444
Effect Of Ezetimibe Coadministration With Simvastatin In A Middle Eastern Population: A Prospective, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial (0653-151)
Not yet reported Organon and Co 120 participants Est. completion 2004-08 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00652717
Study To Assess The Efficacy Of A Cholesterol Lowering Drug On Top Of Statins In Patients After Myocardial Infarction (MI)(0653A-150)
Not yet reported Organon and Co 280 participants Est. completion 2005-08-04 Stand-aloneOther conditions: Cardiovascular DisorderView official trial listing → -
Completed NCT NCT00652847
Randomized Parallel Group Trial Of The Efficacy And Safety Of Ezetimibe With A Statin Versus Statin Dose Doubling In Patients With Persistent Primary Hypercholesterolemia (0653-152)(COMPLETED)
Not yet reported Organon and Co 1140 participants Est. completion 2007-05 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00653276
MD Ezetimibe Cyclosporine Interaction (0653-057)
Not yet reported Organon and Co 13 participants Est. completion 2004-01Other conditions: CholesterolView official trial listing → -
Completed NCT NCT00653445
Compare the Safety & Efficacy of Rosuvastatin 40mg in Combination With Ezetimibe 10mg
Not yet reported AstraZeneca Est. completion 2005-06 Stand-aloneOther conditions: Hypercholesterolemia, Coronary Heart Disease, AtherosclerosisView official trial listing → -
Completed NCT NCT00653523
Coadministration of Ezetimibe and Simvastatin in Patients With Primary Hypercholesterolemia (P05457)
Not yet reported Organon and Co 151 participants Est. completion 2009-06-01 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00653796
Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With High Cholesterol (P03434)
Not yet reported Organon and Co 148 participants Est. completion 2004-08-01 Stand-aloneOther conditions: Hypercholesterolemia, AtherosclerosisView official trial listing → -
Completed NCT NCT00653835
Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)
Not yet reported Organon and Co 153 participants Est. completion 2004-08-01 Stand-aloneOther conditions: Hypercholesterolaemia, AtherosclerosisView official trial listing → -
Completed NCT NCT00653913
Evaluation of Potential for Drug Interaction Between SCH 58235 (Ezetimibe) and Pitavastatin (Study P03962)(COMPLETED)
Not yet reported Organon and Co 18 participants Est. completion 2004-09Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00654095
Coadministration of Ezetimibe and Atorvastatin in Patients With Primary Hypercholesterolemia (P05456)
Not yet reported Organon and Co 146 participants Est. completion 2009-06-01 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00654628
Begin With The Right Patients With Dual-Inhibition Action Therapy Through Vytorin for Newly Diagnosed Dyslipidemia Patients (0653A-172)(COMPLETED)
Not yet reported Organon and Co 173 participants Est. completion 2009-07-01 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Terminated NCT NCT00664469
INdians Followed for INtensive Lipid Lowering Treatment and Its safetY
Not yet reported Sunnybrook Health Sciences Centre 64 participants Est. completion 2010-11 1 site Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00677248
LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe
Not yet reported Karo Bio AB 120 participants Est. completion 2008-10 1 site Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00679237
Risk Reduction in Coronary Heart Disease
Not yet reported Sorlandet Hospital HF 1600 participants Est. completion 2019-12 1 siteOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00681525
A Multiple-Dose Pharmacokinetic Interaction Study Between ABT-335, Atorvastatin and Ezetimibe
Not yet reported Abbott 18 participants 1 site Stand-aloneOther conditions: PharmacokineticsView official trial listing → -
Completed NCT NCT00687076
Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study)
Not yet reported Baylor College of Medicine 102 participants Est. completion 2010-12 1 site Stand-aloneOther conditions: Peripheral Arterial DiseaseView official trial listing → -
Completed NCT NCT00699023
Ezetimibe and Statins on Postprandial Lipemia in Type 2 Diabetes
Not yet reported Federico II University 13 participants Est. completion 2009-10 1 site Stand-aloneType 2 diabetes Other conditions: Postprandial LipemiaView official trial listing → -
Completed NCT NCT00701727
Ezetimibe Reverse Cholesterol Transport (RCT) Pilot Study
Not yet reported Radiant Research 31 participants Est. completion 2009-03 1 site Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00704444
A 12-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05244)
Organon and Co 11332 participants Est. completion 2009-09Other conditions: Hypercholesterolemia, Familial Hypercholesterolemia, Homozygous SitosterolemiaView official trial listing → -
Completed NCT NCT00704535
Evaluation of the Safety, Tolerability and Efficacy of Ezetimibe on a Select Population of Filipinos With Hypercholesterolemia (Study P04748)(COMPLETED)
Organon and Co 4105 participants Est. completion 2008-04Other conditions: Primary Hypercholesterolemia, Homozygous Familial HypercholesterolemiaView official trial listing → -
Completed NCT NCT00705081
Evaluation of the LDL-C Lowering Effects of Ezetimibe Achieved in Co-administration Therapy With Statins in an Indonesian Population (Study P04276)(COMPLETED)
Organon and Co 453 participants Est. completion 2007-12Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00705211
A 52-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05245)
Organon and Co 1794 participants Est. completion 2009-12Other conditions: Hypercholesterolemia, Familial Hypercholesterolemia, Homozygous SitosterolemiaView official trial listing → -
Completed NCT NCT00724477
Retrospective Evaluation of the Percentage of Subjects Who Have Reached Their LDL-C Objectives After Treatment With INEGY (Study P05103)(COMPLETED)
Organon and Co 1663 participants Est. completion 2008-08Other conditions: Primary HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT00725829
Hypolipemic Treatment in Acute Coronary Syndrome (ACS): Antithrombotic Effects
Not yet reported Jagiellonian University 100 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: Acute Coronary SyndromeView official trial listing → -
Completed NCT NCT00726856
Retrospective Survey Evaluating the Effectiveness and Safety of Dual Inhibition Lipid-lowering in the Treatment of Dyslipidemia (Study P05171)(COMPLETED)
Organon and Co 1200 participants Est. completion 2007-07Other conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT00730132
Observational Study of Approaches to Lipid-Lowering Therapy in Russian Patients With Coronary Heart Disease <<Treat to Goal>> (Study P05464)
Organon and Co 712 participants Est. completion 2009-08Other conditions: Coronary Heart Disease, HypercholesterolemiaView official trial listing → -
Completed NCT NCT00738296
Vytorin on Carotid Intima-media Thickness and Overall Rigidity
Not yet reported Hospital Universitario 12 de Octubre 90 participants Est. completion 2005-12 Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT00738972
Left Ventricular Hypertrophy Reduction With Statins in Hypertensives Patients (MK0653A-168)
Not yet reported Fundación Lindavista del Corazón AC 12 participants Est. completion 2010-08 Stand-aloneOther conditions: HypertensionView official trial listing → -
Withdrawn NCT NCT00738985
Efficacy of Ezetimibe/Simvastatin 10/20 mg and MK0524A (1-2 g/Day) in Mixed Hyperlipidemia and Two or More Risk Factors
Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran Est. completion 2010-09Cardiovascular disease Other conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT00753883
Ezetrol Post-Marketing Study
Not yet reported Merck Sharp & Dohme LLC 40 participantsOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT00762164
Comparison of the Effect of Vytorin 10/80 Tablet Split Into 4 and Simvastatin 20 Milligrams on Low-density Lipoprotein (LDL) Cholesterol
Not yet reported Bronx VA Medical Center 34 participants Est. completion 2009-05 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00762229
Evaluation of LDL Cholesterol in Patients Switched From 10 to 5 Milligrams of Zetia (Ezetimibe)
Not yet reported Bronx VA Medical Center 39 participants Est. completion 2008-09 1 site Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00772551
Raltegravir and Ezetimibe PK Study
Not yet reported St Stephens Aids Trust 26 participants Est. completion 2008-08 1 siteOther conditions: HIVView official trial listing → -
Completed NCT NCT00782184
Ezetimibe/Simvastatin (10 mg/40 mg) vs. the Doubling of Atorvastatin in High Risk Participants (MK-0653A-134 AM1)(COMPLETED)
Not yet reported Organon and Co 250 participants Est. completion 2010-09 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00783263
A Study of Ezetimibe Added On to Rosuvastatin Versus Up Titration of Rosuvastatin in Patients With Hypercholesterolemia (MK0653-139)
Not yet reported Organon and Co 440 participants Est. completion 2010-05 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00794677
Effects of Ezetimibe on the Absorption of Oxidized Cholesterol
Not yet reported UCSF Benioff Children's Hospital Oakland 26 participants Est. completion 2008-09 1 site Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00810303
Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2
Not yet reported University Medicine Greifswald 12 participants Est. completion 2009-07 1 site Stand-aloneOther conditions: Pharmacokinetics, Drug Interactions, Pharmacodynamics, Intestinal Transporter ExpressionView official trial listing → -
Completed NCT NCT00814723
Fluvastatin 80 mg Ret. vs Combination With Ezetimibe 10 mg in Patients With High Cardiovascular Risk
Not yet reported Medical University of Graz 90 participants Est. completion 2007-09 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00817843
The PostprAndial eNdothelial Function After Combination of Ezetimibe and simvAstatin Study
Not yet reported dr.Frank L.J. Visseren 100 participants Est. completion 2010-09 5 sites Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT00819403
Simvastatin With or Without Ezetimibe and Atherothrombotic Biomarker Assessment
Not yet reported University of Maryland, Baltimore 15 participants Est. completion 2011-11 3 sitesMetabolic syndromeView official trial listing → -
Status unknown NCT NCT00843661
Coadministration of Ezetimibe With Fenofibrate Versus Pravastatin Monotherapy for the Treatment of Hyperlipidaemia in HIV-infected Patients
Not yet reported Ospedale di Circolo - Fondazione Macchi 60 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: HIV, Hyperlipidemia, HIV InfectionsView official trial listing → -
Status unknown NCT NCT00861731
Ezetimibe/Simvastatin Combination in Proteinuric Nephropathy
Not yet reported Azienda Ospedaliero Universitaria di Sassari 30 participants Est. completion 2009-07 1 siteOther conditions: Hypercholesterolemia, Chronic NephropathyView official trial listing → -
Completed NCT NCT00862251
Ezetimibe/Simvastatin (MK-0653A) Versus Rosuvastatin Versus Doubling Statin Dose in Participants With Cardiovascular Disease and Diabetes Mellitus (MK-0653A-133)(COMPLETED)
Not yet reported Organon and Co 808 participants Est. completion 2011-03 Stand-aloneOther conditions: Cardiovascular Disorder, Diabetes MellitusView official trial listing → -
Completed NCT NCT00863265
Phytosterols, Ezetimibe, and Cholesterol Metabolism
Not yet reported Washington University School of Medicine 22 participants Est. completion 2010-02 1 site Stand-aloneOther conditions: Hypercholesterolemia, Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT00867165
Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)
Not yet reported Organon and Co 138 participants Est. completion 2012-04-13 Stand-aloneOther conditions: Primary HypercholesterolemiaView official trial listing → -
Completed NCT NCT00871351
Evaluation of Ezetimibe and Atorvastatin Coadministration Versus Atorvastatin or Rosuvastatin Monotherapy in Japanese Patients With Hypercholesterolemia (Study P06027)(COMPLETED)
Not yet reported Organon and Co 125 participants Est. completion 2010-05-01 Stand-aloneOther conditions: Primary HypercholesterolemiaView official trial listing → -
Completed NCT NCT00879710
Effect of Diabetes Mellitus on Cholesterol Metabolism
Not yet reported Medical College of Wisconsin 57 participants Est. completion 2013-07 1 siteType 2 diabetes Other conditions: Type 1 Diabetes Mellitus, HypercholesterolemiaView official trial listing → -
Completed NCT NCT00905905
Additive Effect of Ezetimibe Upon Simvastatin During Myocardial Infarction
Not yet reported Brasilia Heart Study Group 40 participants Est. completion 2010-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00908011
Addition of Ezetimibe (Ezetrol®) to Ongoing Therapy With Rosuvastatin (Crestor®) in HIV Positive Patients Not Reaching Cholesterol Targets
Not yet reported University of British Columbia 43 participants Est. completion 2015-01 1 siteOther conditions: Hypercholesterolemia, HIV InfectionsView official trial listing → -
Completed NCT NCT00909389
Post-marketing Surveillance of the Safety, Tolerability and Efficacy of Vytorin (Ezetimibe + Simvastatin) Tablet Among Filipino Patients (Study P05647)
Organon and Co 4748 participants Est. completion 2008-11Other conditions: HypercholesterolemiaView official trial listing → -
Withdrawn NCT NCT00926055
Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET)
Not yet reported Korea University 1 site Stand-aloneOther conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT00932620
Comparison of Simvastatin Versus Simvastatin/Ezetimibe on Small Dense Low -Density Lipoprotein (LDL)
Not yet reported University of Ioannina 100 participants Est. completion 2010-04 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT00952770
Effect of Statins on the Radial Intima-media Thickness After Transradial Angioplasty
Not yet reported Chungnam National University 140 participants 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00955227
Can Cholesterol Lowering Drugs Influence Circulating Omega-3 Fatty Acid Levels
Not yet reported University of Manitoba 60 participants Est. completion 2015-12 2 sites Stand-aloneOther conditions: Hypercholesterolemia, HyperlipidemiaView official trial listing → -
Terminated NCT NCT00965055
Ezetimibe in Patients Hypo-responsive to Statins
Not yet reported University of California, San Diego 2 participants Est. completion 2012-09 1 site Stand-aloneCardiovascular disease Other conditions: High CholesterolView official trial listing → -
Status unknown NCT NCT00972829
Tolerability and Lipid Lowering Effect of Weekly/Biweekly Crestor in Statin Intolerant Patients Treated With Zetia
Not yet reported Bronx VA Medical Center 30 participants Est. completion 2011-03 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT00988364
Effects of Ezetimibe, Simvastatin, and Vytorin on Reducing L5 a Subfraction of LDL in Patients With Metabolic Syndrome.
Not yet reported Baylor College of Medicine 30 participants Est. completion 2008-02 1 siteMetabolic syndromeView official trial listing → -
Completed NCT NCT01008345
Effect of Ezetimibe on Oxidized Low-density Lipoprotein (LDL) Cholesterol
Not yet reported Hotel Dieu de France Hospital 100 participants Est. completion 2009-06 1 site Stand-aloneCardiovascular disease Other conditions: DiabetesView official trial listing → -
Completed NCT NCT01035320
Platelet Function in Diabetic Patients With and Without Renal Impairment, and the Effects of Lipid Lowering Treatment
Not yet reported Karolinska Institutet 39 participants Est. completion 2012-06 1 site Stand-aloneOther conditions: Diabetes Mellitus, Impaired Renal FunctionView official trial listing → -
Completed NCT NCT01043380
Plaque REgression With Cholesterol Absorption Inhibitor or Synthesis Inhibitor Evaluated by IntraVascular UltraSound
Not yet reported Kumamoto University 245 participants Est. completion 2014-09 1 site Stand-aloneCardiovascular disease Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01047501
Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL)
Not yet reported Amarin Pharma Inc. 702 participants Est. completion 2011-02 80 sitesOther conditions: HypertriglyceridemiaView official trial listing → -
Completed NCT NCT01047683
Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL
Not yet reported Amarin Pharma Inc. 229 participants Est. completion 2011-07 60 sitesOther conditions: HypertriglyceridemiaView official trial listing → -
Status unknown NCT NCT01068093
The Effects of Ezetimibe on Coronary Plaque Volume in Patients With Acute Coronary Syndrome
Not yet reported Yokohama City University Medical Center 120 participants Est. completion 2015-10 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01070953
EZETROL® Re-examination Study (MK0653-175)(COMPLETED)
Organon and Co 4467 participants Est. completion 2010-07Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01070966
Vytorin Reexamination Study (0653A-174)
Organon and Co 2089 participants Est. completion 2010-04Other conditions: Primary Hypercholesterolemia and Homozygous Familial Hypercholesterolemia (HoFH)View official trial listing → -
Completed NCT NCT01077830
An Observational Follow-Up Study of the Incidence of Cancer and Mortality in Patients From the SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) Trial (MK-0653A-043-10)
Organon and Co 1392 participants Est. completion 2013-04Other conditions: CancerView official trial listing → -
Status unknown NCT NCT01086020
Atorvastatin Plus Ezetimibe on Coronary Plaque Progression
Not yet reported Shanghai Jiao Tong University School of Medicine 400 participants Est. completion 2012-12 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01103648
Effect of Simvastatin and Ezetimibe on Lipid and Inflammation
Not yet reported Federal University of São Paulo 50 participants Est. completion 2007-11 1 site Stand-alonePrediabetes Other conditions: Hypercholesterolemia, Inflammation, Cardiovascular RiskView official trial listing → -
Completed NCT NCT01112423
Safety Study of BMS-823778 in Subjects With Hypercholesterolemia
Not yet reported Bristol-Myers Squibb 60 participants Est. completion 2010-12 12 sitesOther conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT01154036
MK0653C in High Cardiovascular Risk Patients With High Cholesterol (Switch Study)(MK-0653C-162)
Not yet reported Organon and Co 1547 participants Est. completion 2012-10 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01164397
Efficiency of Rosuvastatin Versus the Fixed Combination of Ezetimibe/Simvastatin in Outpatients
AstraZeneca 268 participants Est. completion 2010-12 9 sitesOther conditions: DyslipidemiaView official trial listing → -
Status unknown NCT NCT01185236
Study to Compare the Effect of Vytorin (Simvastatin/Ezetimibe) 10/20mg Versus Atorvastatin 20mg on ApoB/ApoA1 Ratio in Subjects With Diabetes
Not yet reported Seoul National University Hospital 132 participants Est. completion 2011-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01218204
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Administering Multiple Oral Doses of GSK1292263 Alone and With Atorvastatin
Not yet reported GlaxoSmithKline 287 participants Est. completion 2011-06-29 21 sites Stand-aloneOther conditions: Dyslipidaemias, DyslipidemiasView official trial listing → -
Completed NCT NCT01236430
A Study to Determine the Bioequivalence of SCH 900068 Compared to Marketed Products (Protocol No. P07551)
Not yet reported Organon and Co 200 participants Est. completion 2012-02 Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Status unknown NCT NCT01241097
Pleiotropism of Statin Therapy in High Dose Versus Low Dose Combined With Ezetimibe
Not yet reported Federal University of Bahia 60 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Endothelial FunctionView official trial listing → -
Completed NCT NCT01266876
Study of the Safety and Efficacy of REGN727/SAR236553 in Patients With HeFH Hypercholesterolemia
Not yet reported Regeneron Pharmaceuticals 77 participants Est. completion 2011-11 22 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Terminated NCT NCT01308203
Lipid Efficacy of the Extended Release Niacin/Laropiprant Combination in Patients With Cardiovascular Disease
Not yet reported Daniel A. Siniawski 32 participants Est. completion 2013-01 1 site Stand-aloneCardiovascular disease Other conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT01370590
A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1)
Not yet reported Organon and Co 406 participants Est. completion 2012-04 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01370603
A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/40 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 40 mg Tablets in Participants With High Cholesterol (MK-0653C-190 AM1)
Not yet reported Organon and Co 328 participants Est. completion 2012-05 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01375764
Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects
Not yet reported Amgen 160 participants Est. completion 2012-05-08 42 sites Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT01375777
Monoclonal Antibody Against PCSK9 to Reduce Elevated Low-density Lipoprotein Cholesterol (LDL-C) in Adults Currently Not Receiving Drug Therapy for Easing Lipid Levels
Not yet reported Amgen 411 participants Est. completion 2012-03-02 58 sitesOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT01381679
Effect of Ezetimibe Treatment on Low-density Lipoprotein Cholesterol (LDL-C) Levels in Participants With Coronary Heart Disease (CHD) Already Treated With a Statin (MK-0653A-205 AM1)
Organon and Co 1682 participants Est. completion 2010-12Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01384058
Effect of Ezetimibe or Simvastatin or Both on Low Densitiy Lipoprotein -Subfractions in Patients With Type 2 Diabetes
Not yet reported University Hospital Freiburg 41 participants Est. completion 2010-06 2 sitesType 2 diabetes Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01385631
Ezetimibe In Addition To Atorvastatin Therapy On The Plaque Composition In Patients With Acute Myocardial Infarction.
Not yet reported Odense University Hospital 87 participants Est. completion 2014-09 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01414192
A Study to Design a Model Cohort for Analysis of Dyslipidemia (MK-0653A-204)
Organon and Co 3215 participants Est. completion 2014-09-15Other conditions: Dyslipidemia, HypercholesterolemiaView official trial listing → -
Completed NCT NCT01420328
To Study the Effect of Vytorin on Intracellular Lipid and Inflammation in Obese Subjects
Not yet reported University at Buffalo 20 participants Est. completion 2016-07-01 1 siteOther conditions: InflammationView official trial listing → -
Completed NCT NCT01420549
Efficacy/Safety of Rosuvastatin+Ezetimibe in High Risk Patients With Primary Hypercholesterolemia/Mixed Dyslipidemia
Not yet reported Ache Laboratorios Farmaceuticos S.A. 129 participants Est. completion 2014-11 7 sites Stand-aloneOther conditions: Hypercholesterolemia, DyslipidemiaView official trial listing → -
Completed NCT NCT01424891
Effects on NF-κB Activity: High Dose Simvastatin Versus Combination Therapy With Ezetimibe
Not yet reported Heidelberg University 31 participants Est. completion 2011-08 1 siteType 2 diabetes Other conditions: InflammationView official trial listing → -
Status unknown NCT NCT01490229
Ezetimibe Versus Nutraceuticals in Statin-intolerant Patients
Not yet reported University of Roma La Sapienza 100 participants Est. completion 2016-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01492361
A Study of AMR101 to Evaluate Its Ability to Reduce Cardiovascular Events in High-Risk Patients With Hypertriglyceridemia and on Statin
Not yet reported Amarin Pharma Inc. 8179 participants Est. completion 2018-05 410 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01516879
Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study
Not yet reported Amgen 905 participants Est. completion 2013-10-14 96 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01520077
Vytorin in the Treatment of Alopecia Areata
Not yet reported University of Miami 29 participants Est. completion 2015-01 1 siteOther conditions: Alopecia AreataView official trial listing → -
Completed NCT NCT01584206
Sitosterolemia Metabolism
Not yet reported University of Manitoba 8 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: SitosterolemiaView official trial listing → -
Withdrawn NCT NCT01587235
A Study to Evaluate the Efficacy and Safety of Vytorin Versus Standard Treatment of Other Statins in Moderate, Moderately High and High Risk Participants (MK-0653A-406)
Not yet reported Organon and Co Est. completion 2014-05 Stand-aloneOther conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT01597700
Acotral® Versus Zetia® Ezetimibe Bioequivalance Study.
Not yet reported GlaxoSmithKline 52 participants Est. completion 2012-01-30 1 site Stand-aloneOther conditions: HypercholesterolaemiaView official trial listing → -
Completed NCT NCT01603758
Physiological Study of Human Cholesterol Metabolism and Excretion
Not yet reported Richard E. Ostlund Jr., MD 132 participants Est. completion 2015-06 1 siteCardiovascular disease Other conditions: Coronary Heart Disease, Dyslipidemia, Disorder of Cholesterol MetabolismView official trial listing → -
Completed NCT NCT01611883
A Study of the Effect of Ezetimibe on Glucose Metabolism in Type 2 Diabetics With Hypercholesterolemia (P06541)
Not yet reported Organon and Co 152 participants Est. completion 2014-01-16 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01644188
Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe on Top of Statin in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY COMBO II)
Not yet reported Sanofi 720 participants Est. completion 2015-07 126 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01644474
Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe in Patients With Hypercholesterolemia
Not yet reported Sanofi 103 participants Est. completion 2013-07 8 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01660945
Vascular and Metabolic Effects of Vytorin
Not yet reported Gachon University Gil Medical Center 204 participants Est. completion 2012-11 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01666067
Vascular and Metabolic Effects of Vytorin vs Simvastatin
Not yet reported Gachon University Gil Medical Center 204 participants Est. completion 2012-11 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01709513
Study of Alirocumab (REGN727/SAR236553) in Patients With Primary Hypercholesterolemia and Moderate, High, or Very High Cardiovascular (CV) Risk, Who Are Intolerant to Statins (ODYSSEY ALTERNATIVE)
Not yet reported Regeneron Pharmaceuticals 314 participants Est. completion 2017-05-31 70 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01723735
Effect of Alirocumab (SAR236553/REGN727) Administered on Top of Ezetimibe or Fenofibrate on Lipid Profiles in Healthy Subjects
Not yet reported Sanofi 79 participants Est. completion 2013-07 2 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01730040
Study of the Efficacy and Safety of Alirocumab (REGN727/SAR236553) in Combination With Other Lipid-modifying Treatment (LMT) (ODYSSEY OPTIONS I)
Not yet reported Regeneron Pharmaceuticals 355 participants Est. completion 2014-05 97 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01730053
Study of Alirocumab (REGN727/SAR236553) added-on to Rosuvastatin Versus Other Lipid Modifying Treatments (LMT) (ODYSSEY OPTIONS II)
Not yet reported Regeneron Pharmaceuticals 305 participants Est. completion 2014-05-31 93 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01763827
Monoclonal Antibody Against PCSK9 to Reduce Elevated LDL-C in Subjects Currently Not Receiving Drug Therapy for Easing Lipid Levels-2
Not yet reported Amgen 615 participants Est. completion 2013-10-29 83 sites Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT01763866
LDL-C Assessment With PCSK9 Monoclonal Antibody Inhibition Combined With Statin Therapy-2
Not yet reported Amgen 2067 participants Est. completion 2013-12-04 244 sites Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT01763905
Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2
Not yet reported Amgen 307 participants Est. completion 2013-11-19 58 sites Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT01766713
Ezetimibe Versus Placebo in the Treatment of Non-alcoholic Steatohepatitis
Not yet reported University of California, San Diego 50 participants Est. completion 2014-09 1 site Stand-aloneOther conditions: Non Alcoholic SteatohepatitisView official trial listing → -
Status unknown NCT NCT01807078
Cholesterol-lowering Effects of nutraceuticaLs Versus Ezetimibe in Statin-intolerant Patients
Not yet reported University of Roma La Sapienza 200 participants Est. completion 2017-12 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT01849068
Effects of Selective Inhibition of Cholesterol Absorption With Ezetimibe on Intestinal Cholesterol Homeostasis in Dyslipidemic Men With Insulin-resistance - a Pilot Study
Not yet reported Laval University 20 participants Est. completion 2016-02 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT01857843
Early Effects of Intensive Lipid Lowering Treatment With Ezetimibe/ Simvastatin (Vytorin®) Assessed by Virtual Histology-Intravascular Ultrasound (VH-IVUS) and Optical Coherence Tomography (OCT) on Plaque Characteristics in Patients With Acute Coronary Syndrome
Not yet reported Yonsei University 160 participants Est. completion 2014-01 1 site Stand-aloneOther conditions: Acute Coronary SyndromeView official trial listing → -
Status unknown NCT NCT01890889
Study of Changes in Total Cholesterol Levels as a Function of Consuming a Supplement Designed to Improve Cardiovascular Health
Not yet reported Integrative Health Technologies, Inc. 150 participants Est. completion 2013-12 1 siteOther conditions: Cholesterol, Hyperlipidemia, HypercholesteremiaView official trial listing → -
Completed NCT NCT01890967
A Study of LY3015014 in Participants With High Cholesterol
Not yet reported Eli Lilly and Company 527 participants Est. completion 2014-06 49 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT01941836
Evaluation of ETC-1002, Ezetimibe, and the Combination in Hypercholesterolemic Patients
Not yet reported Esperion Therapeutics, Inc. 349 participants Est. completion 2014-11 68 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT01950884
Lifestyle Versus Ezetimibe Plus Lifestyle in Patients With Non-alcoholic Steatohepatitis
Not yet reported University of Palermo 45 participants Est. completion 2014-12 1 site Stand-aloneMASHView official trial listing → -
Completed NCT NCT01984424
Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-3
Not yet reported Amgen 511 participants Est. completion 2017-11-21 58 sites Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT02023879
Phase III Study To Evaluate Alirocumab in Patients With Hypercholesterolemia Not Treated With a Statin (ODYSSEY CHOICE II)
Not yet reported Sanofi 233 participants Est. completion 2017-06-30 43 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT02029625
Compare the Pharmacokinetics of NVP-1205 and Coadministration of Rosuvastatin and Ezetimibe
Not yet reported NVP Healthcare 41 participants Est. completion 2014-03 1 site Stand-aloneOther conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT02055976
Dose Ranging Study Of Bococizumab (PF-04950615; RN316) In Hypercholesterolemic Japanese Subjects
Not yet reported Pfizer 218 participants Est. completion 2015-01 9 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT02089867
Plant Sterols Effect on Previous Statin Therapy
Not yet reported, Not yet reported Jose Rocha Faria Neto 47 participants Est. completion 2008-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02103049
The Impact of Ezetimibe on Biochemical Markers of Cardiovascular Risk in Kidney Transplant Patients
Not yet reported University Medical Centre Ljubljana 80 participants Est. completion 2015-12 1 siteOther conditions: Dyslipidemia, TransplantsView official trial listing → -
Status unknown NCT NCT02126137
Pilot Study of Ezetimibe for Chronic Hepatitis C Virus (HCV) Infection
Not yet reported Pontificia Universidad Catolica de Chile 20 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT02127320
Investigating the Pharmacokinetic Drug Interactions Between Rosuvastatin and Ezetimibe
Not yet reported Hanmi Pharmaceutical Company Limited 24 participants Est. completion 2014-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02129231
Statins for Oxidative Stress and Mitochondrial Function in Diabetic Polyneuropathy
Not yet reported University of Guadalajara 74 participants Est. completion 2014-04 1 siteOther conditions: Oxidative Stress, Diabetic PolyneuropathyView official trial listing → -
Terminated NCT NCT02205775
Rosuvastatin for Reduction of Myocardial Damage and Systemic Inflammation During Coronary Angioplasty
Not yet reported G. d'Annunzio University 280 participants Est. completion 2012-06 6 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT02227784
A Study of Evacetrapib (LY2484595) in Participants With High Cholesterol
Not yet reported Eli Lilly and Company 366 participants Est. completion 2015-12 64 sitesOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT02234544
Effect of an Inhibitor of Cholesterol Absorption on Vitamin D Levels
Not yet reported Federal University of Rio Grande do Sul 52 participants Est. completion 2015-04 1 siteOther conditions: Vitamin D DeficiencyView official trial listing → -
Terminated NCT NCT02244944
Ezetimibe-Ursodiol Combination Therapy on Biomarkers of Liver Function and Sterol Balance in Subjects With NAFLD
Not yet reported Gregory Graf, PhD 2 participants Est. completion 2015-09 1 site Stand-aloneMASLDView official trial listing → -
Status unknown NCT NCT02251847
The Efficacy and Safety of a Combination Therapy of Rosuvastatin and Ezetimibe Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients
Not yet reported IlDong Pharmaceutical Co Ltd 400 participants 1 site Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Terminated NCT NCT02260648
A Study of Evacetrapib (LY2484595) in Combination With Atorvastatin in Japanese Participants With Primary Hypercholesterolemia
Not yet reported Eli Lilly and Company 149 participants Est. completion 2015-11 8 sitesOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT02288338
CKD-391 DDI : Atorvastatin and Ezetimibe in Healthy Volunteers
Not yet reported Chong Kun Dang Pharmaceutical 36 participants Est. completion 2015-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02289430
to Investigate the Pharmacokinetic Interactions and Safety Between Rosuvastatin and Ezetimibe in Healthy Male Volunteers
Not yet reported NVP Healthcare 59 participants Est. completion 2015-02 Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02304926
Effects of Simvastatin and Ezetimibe on Cardiovascular Risk Markers in Patients With Dyslipidemia
Not yet reported Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana 42 participants Est. completion 2011-12 Stand-aloneOther conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT02445352
Efficacy/Safety of DP-R207 Tablet Versus CRESTOR Tablet in Patients With Primary Hypercholesterolemia
Not yet reported Alvogen Korea 379 participants Est. completion 2015-03 1 siteOther conditions: Primary HypercholesterolemiaView official trial listing → -
Completed NCT NCT02451098
Clinical Trial to Evaluate the Efficacy and Safety of CKD-391
Not yet reported Chong Kun Dang Pharmaceutical 385 participants Est. completion 2016-01 1 site Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT02460159
A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384)
Not yet reported Organon and Co 135 participants Est. completion 2016-12-22Other conditions: Hypercholesterolemia, Heterozygous Familial HypercholesterolemiaView official trial listing → -
Completed NCT NCT02461004
CKD-391 Pharmacokinetic Study
Not yet reported Chong Kun Dang Pharmaceutical 52 participants Est. completion 2015-10 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02476006
Safety, Tolerability, and Effect of Alirocumab in High Cardiovascular Risk Patients With Severe Hypercholesterolemia Not Adequately Controlled With Conventional Lipid-modifying Therapies (ODYSSEY APPRISE)
Not yet reported Sanofi 998 participants Est. completion 2019-04-12 153 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT02501200
CKD-391 Pharmacokinetic Study Phase I
Not yet reported Chong Kun Dang Pharmaceutical 46 participants Est. completion 2015-12 Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02534376
Cellular Effect of Cholesterol-Lowering Prior to Prostate Removal
Not yet reported Cedars-Sinai Medical Center 63 participants Est. completion 2019-02-28 1 site Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT02547402
A Study of the PK Interaction of CXA-10 With Pravastatin and Vytorin® in Healthy Males
Not yet reported Complexa, Inc. 10 participants Est. completion 2016-02 1 site Stand-aloneOther conditions: Acute Kidney InjuryView official trial listing → -
Status unknown NCT NCT02548936
Efficacy and Safety of Simvastatin-ezetimibe Combination Therapy Among Patients With SLE
Not yet reported Peking Union Medical College Hospital 30 participants Est. completion 2016-12 1 site Stand-aloneOther conditions: AtherosclerosisView official trial listing → -
Completed NCT NCT02550288
A Clinical Trial to Assess the Efficacy and Safety of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-383)
Not yet reported Organon and Co 309 participants Est. completion 2016-05-30 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT02584504
Efficacy and Safety of Alirocumab in Patients With Hypercholesterolemia Not Adequately Controlled With Non-statin Lipid Modifying Therapy or the Lowest Strength of Statin
Not yet reported Sanofi 163 participants Est. completion 2018-01-09 30 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT02588235
Ezetimibe and Atorvastatin Therapy on TCFA
Not yet reported Xijing Hospital 100 participants Est. completion 2017-11 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT02634580
Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects-4
Not yet reported Amgen 61 participants Est. completion 2018-05-26 35 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT02642159
Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)
Not yet reported Sanofi 413 participants Est. completion 2017-05-15 119 sitesOther conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT02682680
Randomized Trial Comparing Colesevelam vs. Ezetimibe
Not yet reported LMC Diabetes & Endocrinology Ltd. 200 participants Est. completion 2017-05-25 9 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02715726
Evaluation of Alirocumab Versus Ezetimibe on Top of Statin in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia
Not yet reported Sanofi 615 participants Est. completion 2018-08-06 62 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT02730689
A Study to Compare the Pharmacokinetics of DP-R207 in Comparison to Each Component Administered Alone
Not yet reported Alvogen Korea 66 participants Est. completion 2015-01 Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02741245
A Study of the Efficacy and Safety of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-832)
Not yet reported Organon and Co 321 participants Est. completion 2017-01-18 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT02748057
A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-833)
Not yet reported Organon and Co 135 participants Est. completion 2017-12-11 Stand-aloneOther conditions: Hypercholesterolemia, Familial HypercholesterolemiaView official trial listing → -
Completed NCT NCT02749994
A Clinical Trial to Compare the Efficacy and Safety of a Combination Therapy of Ezetimibe and Rosuvastatin Versus Monotherapy of Rosuvastatin in Hypercholesterolemia Patients (I-ROSETTE Study)
Not yet reported IlDong Pharmaceutical Co Ltd 396 participants Est. completion 2017-02 1 site Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Terminated NCT NCT02755194
"Drugs in Lactation" Analysis Consortium
The Hospital for Sick Children 68 participants Est. completion 2019-09-25 1 siteOther conditions: LactationView official trial listing → -
Completed NCT NCT02767362
A Pre-Op Window Study Evaluating Anti-Proliferative Effects of Atorvastatin on the Endometrium
Not yet reported UNC Lineberger Comprehensive Cancer Center 24 participants Est. completion 2019-09-26 1 siteOther conditions: Endometrial CancerView official trial listing → -
Status unknown NCT NCT02768545
Study of Ezetimibe for Chronic Hepatitis C Virus (HCV) Infection in Liver Transplant Candidates (EZE-2)
Not yet reported Pontificia Universidad Catolica de Chile 12 participants Est. completion 2016-06 1 site Stand-aloneOther conditions: Hepatitis CView official trial listing → -
Completed NCT NCT02772640
Effectiveness of Treatment of Hypercholesterolemia With Rosuvastatin and Ezetimibe
Not yet reported Collegium Medicum w Bydgoszczy 83 participants Est. completion 2020-05 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT02890992
An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia
Not yet reported Sanofi 42 participants Est. completion 2019-02-22 16 sites Stand-aloneOther conditions: HypercholesterolaemiaView official trial listing → -
Completed NCT NCT02942602
Effect of Lipid Modifying Drugs on HDL Function in Patients With Hyperlipidemia
Not yet reported Yonsei University 58 participants Est. completion 2016-05-23 1 site Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Terminated NCT NCT02971033
Ezetimibe as a Safe and Efficacious Treatment for Chronic Hepatitis C
Not yet reported VA Office of Research and Development 2 participants Est. completion 2021-03-31 1 site Stand-aloneOther conditions: Chronic Hepatitis CView official trial listing → -
Completed NCT NCT02984982
Evaluation of Effect of Alirocumab on Coronary Atheroma Volume in Japanese Patients Hospitalized for Acute Coronary Syndrome With Hypercholesterolemia
Not yet reported Sanofi 206 participants Est. completion 2018-07-27 39 sites Stand-aloneOther conditions: Hypercholesterolemia, Acute Coronary SyndromeView official trial listing → -
Completed NCT NCT03001076
Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)
Not yet reported Esperion Therapeutics, Inc. 269 participants Est. completion 2018-02-12 1 site Stand-aloneOther conditions: Hypercholesterolemia, Atherosclerosis, Statin Adverse ReactionView official trial listing → -
Status unknown NCT NCT03044665
RAndomized Comparison of Efficacy and Safety of Lipid-lowerING With Statin Monotherapy Versus Statin/Ezetimibe Combination for High-risk Cardiovascular Diseases (RACING Trial)
Not yet reported Yonsei University 3780 participants Est. completion 2023-02-15 1 site Stand-aloneCardiovascular disease Other conditions: Cerebrovascular Disease, Peripheral Atherosclerotic DiseaseView official trial listing → -
Completed NCT NCT03051100
Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-C
Not yet reported Esperion Therapeutics, Inc. 63 participants Est. completion 2017-07-05 11 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT03099278
Ezetimibe for Patients With Chronic Hepatitis D
Not yet reported Ziauddin Hospital 20 participants Est. completion 2017-10 1 site Stand-aloneOther conditions: Chronic Hepatitis DView official trial listing → -
Status unknown NCT NCT03105310
Pegylated Interferon Alone or in Combination With Ezetimibe for Patients With Chronic Hepatitis D
Not yet reported Aga Khan University 20 participants Est. completion 2017-06 Stand-aloneOther conditions: Hepatitis D, ChronicView official trial listing → -
Completed NCT NCT03110432
Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry
GWT-TUD GmbH 1695 participants Est. completion 2024-04-17 3 sitesOther conditions: Dyslipoproteinemias, Hypercholesterolemia, Familial, Familial Hypercholesterolemia - Homozygous, Familial Combined HyperlipidemiaView official trial listing → -
Active, not recruiting NCT NCT03169985
Randomized Controlled Trial of Moderate-Intensity Rosuvastatin With Ezetimibe Combination Therapy Versus High-Intensity Rosuvastatin on Progression of Coronary Atherosclerotic Plaque
Not yet reported Samsung Medical Center 280 participants Est. completion 2027-01-28 1 siteCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT03204799
Metagenomic Analysis of Human Gut Microbiota in Patients With Metabolic Diseases Including Diabetes
Yonsei University 150 participants Est. completion 2019-12-16 1 siteType 2 diabetes Other conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT03217409
A Study to Compare Rosuvastatin/Ezetimibe and Rosuvastatin in Patients With Diabetes Mellitus and Hypercholesterolemia
Not yet reported Yuhan Corporation 85 participants Est. completion 2019-05-23 4 sites Stand-aloneOther conditions: Diabetes Mellitus and HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT03277079
Low Dose Statins, Ezetimibe and Nutraceuticals
Not yet reported University of Roma La Sapienza 100 participants Est. completion 2018-03-31 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT03288038
The Efficacy and Safety of Combination Therapy of Rosuvastatin and Ezetimibe and Rosuvastatin Monotherapy in Patients With Primary Hypercholesterolemia
Not yet reported Shin Poong Pharmaceutical Co. Ltd. 382 participants Est. completion 2015-11-19 20 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT03337308
A Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin Therapy
Not yet reported Esperion Therapeutics, Inc. 382 participants Est. completion 2018-07-18 5 sites Stand-aloneOther conditions: HyperlipidemiasView official trial listing → -
Status unknown NCT NCT03355027
Investigating the Lowest Threshold of Vascular Benefits From LDL Cholesterol Lowering in Patients With Stable CV Disease
Not yet reported Cambridge University Hospitals NHS Foundation Trust 60 participants Est. completion 2023-11-30 1 siteCardiovascular disease Other conditions: AtherosclerosisView official trial listing → -
Status unknown NCT NCT03403556
High-intensity Rosuvastatin vs. Moderate-intensity Rosuvastatin/Ezetimibe in High Atherosclerotic Cardiovascular Disease Risk Patients With Type 2 Diabetes
Not yet reported Yuhan Corporation 140 participants Est. completion 2021-12 6 sitesCardiovascular diseaseType 2 diabetesView official trial listing → -
Status unknown NCT NCT03430284
Multifactorial Intervention on Diabetes (MIDiab Study)
Not yet reported Shandong Provincial Hospital 6300 participants Est. completion 2022-12-31 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03434613
Phase IV Study to Evaluate the Effects of Statin Monotherapy or Statin / Ezetimibe Combination Therapy on Hepatic Steatosis in Patients With Hyperlipidemia and Nonalcoholic Fatty Liver Disease
Not yet reported Yonsei University 64 participants Est. completion 2019-09-11 1 site Stand-aloneMASLD Other conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT03446261
Rosuvastatin/Ezetimibe vs Rosuvastatin in Korean Patients With Type 2 Diabetes Mellitus and Hypercholesterolemia
Not yet reported Yuhan Corporation 140 participants Est. completion 2019-03-05 2 sites Stand-aloneType 2 diabetes Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT03494270
High-intensity Rosuvastatin and Moderate-intensity Rosuvastatin/Ezetimibe in ASCVD Patients
Not yet reported Yuhan Corporation 270 participants Est. completion 2019-09-26 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT03510715
An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia
Not yet reported Sanofi 18 participants Est. completion 2020-02-17 10 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT03510884
An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia
Not yet reported Sanofi 153 participants Est. completion 2022-08-05 43 sites Stand-aloneOther conditions: HypercholesterolaemiaView official trial listing → -
Completed NCT NCT03531905
Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-C
Not yet reported Esperion Therapeutics, Inc. 242 participants Est. completion 2019-06-18 4 sites Stand-aloneType 2 diabetes Other conditions: Diabetes, CholesterolemiaView official trial listing → -
Completed NCT NCT03532854
Evaluating a Pharmacokinetic Drug Interaction Between LGEV1801 and LGEV1802
Not yet reported LG Chem 42 participants Est. completion 2019-01-30 1 site Stand-aloneOther conditions: Healthy Male VolunteersView official trial listing → -
Status unknown NCT NCT03543774
Lipid-lowering Therapies in Vietnamese Chronic Kidney Disease Population
Not yet reported Hue University of Medicine and Pharmacy 30 participants Est. completion 2020-10-15 1 siteChronic kidney disease Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT03571087
Efficacy and Safety of Combination of Rosuvastatin and Ezetimibe in Patients With Primary Hypercholesterolemia
Not yet reported Hanlim Pharm. Co., Ltd. 374 participants Est. completion 2015-09Other conditions: Primary HypercholesterolemiaView official trial listing → -
Completed NCT NCT03597412
Rosuvastatin/Ezetimibe Versus Rosuvastatin in ASCVD Patients With Type 2 DM
Not yet reported Yuhan Corporation 236 participants Est. completion 2020-08-12 1 site Stand-aloneCardiovascular diseaseType 2 diabetesView official trial listing → -
Status unknown NCT NCT03648788
A Post-marketing Surveillance to Assess Safety and Efficacy of Rosuvatatin/Ezetimibe
IlDong Pharmaceutical Co Ltd 600 participants Est. completion 2024-08Other conditions: Mixed DyslipidemiaView official trial listing → -
Withdrawn NCT NCT03750760
Early Alirocumab to Reduce LDL-C in Myocardial Infarction
Not yet reported Imperial College London Est. completion 2021-12 17 sitesCardiovascular disease Other conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT03768427
Ezetimibe (EZ)/Atorvastatin (Ator) (MK-0653C) vs. Ator in Chinese Hypercholesterolemic Participants (MK-0653C-439)
Not yet reported Organon and Co 454 participants Est. completion 2021-04-01 30 sitesOther conditions: HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT03771053
The Effect of Simvastatin Combined With Ezetimibe in Patients With Stable Angina and Diabetes
Not yet reported Chinese PLA General Hospital 240 participants Est. completion 2019-12-31 1 site Stand-aloneOther conditions: Coronary Heart DiseaseView official trial listing → -
Completed NCT NCT03847506
Evaluate Efficacy and Safety of Ezetimibe/Rosuvastatin and Candesartan Cilexetil/Amlodipine Besylate Combination Tablets
Not yet reported HK inno.N Corporation 127 participants Est. completion 2020-12-02 1 site Stand-aloneOther conditions: Hypertension, HyperlipidemiaView official trial listing → -
Completed NCT NCT03867110
An Efficacy and Safety Study of Ezetimibe (MK-0653, SCH 58235) in Addition to Atorvastatin Compared to Placebo in Participants With Primary Hypercholesterolemia (MK-0653-013)
Not yet reported Organon and Co 628 participants Est. completion 2001-07-27 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT03867318
Efficacy and Safety Study of Ezetimibe (SCH 58235, MK-0653) in Addition to Atorvastatin in Participants With Coronary Heart Disease or Multiple Cardiovascular Risk Factors (P00693/MK-0653-030)
Not yet reported Organon and Co 621 participants Est. completion 2001-11-16 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT03872232
Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan
Not yet reported Addpharma Inc. 180 participants Est. completion 2020-08-12 1 site Stand-aloneOther conditions: Hypercholesterolemia, HypertensionView official trial listing → -
Status unknown NCT NCT03877783
DEMAND - Multifactorial Study to Reduce Dementia in People With Type 2 Diabetes
Not yet reported Umeå University 10 participants Est. completion 2023-06-30 1 siteType 2 diabetes Other conditions: Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT03882892
Long-Term Safety and Tolerability of Ezetimibe (SCH 58235, MK-0653) With Atovastatin (P02154, MK-0653-017)
Not yet reported Organon and Co 400 participants Est. completion 2002-08-08 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT03882905
A Study of SCH 58235 (Ezetimibe) When Added to Ongoing Therapy With a Statin in Participants With Primary Hypercholesterolemia, Known Coronary Heart Disease, or Multiple Cardiovascular Risk Factors (P02173)
Not yet reported Organon and Co 769 participants Est. completion 2001-07-27 Stand-aloneOther conditions: Primary HypercholesterolemiaView official trial listing → -
Completed NCT NCT03882996
A Long-term Safety and Tolerability Study of Ezetimibe Plus Atorvastatin in Participants With Coronary Heart Disease, Multiple Risk Factors, or Hypercholesterolemia Not Controlled by Atorvastatin (P01418/MK-0653-032)
Not yet reported Organon and Co 432 participants Est. completion 2003-02-04 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT03884127
Ezetimibe and Orlistat Affect the Intestinal Flora of Hyperlipidemia.
Fifth Affiliated Hospital of Xinjiang Medical University 58 participants Est. completion 2019-09-30Other conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT03884452
Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018)
Not yet reported Organon and Co 50 participants Est. completion 2001-05-24 Stand-aloneOther conditions: Familial HypercholesterolemiaView official trial listing → -
Completed NCT NCT03885921
Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)
Not yet reported Organon and Co 44 participants Est. completion 2003-07-08 Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT03933293
A Study to Evaluate the Safety and Efficacy of the PCSK9 Inhibitor AK102 in Patients With HoFH
Not yet reported Akeso 10 participants Est. completion 2021-03-15 2 sites Stand-aloneOther conditions: Homozygous Familial HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT03947866
Ezetimibe-Rosuvastatin Evaluation Study
Elpen Pharmaceutical Co. Inc. 600 participants Est. completion 2023-09-30 1 siteOther conditions: Hypercholesterolemia, Hyperlipidemias, Combinations of Drugs; DependenceView official trial listing → -
Completed NCT NCT03993236
Study on Rosuvastatin+Ezetimibe and Rosuvastatin for LDL-C Goal in Patients With Recent Ischemic Stroke
Not yet reported Keun-Sik Hong 584 participants Est. completion 2021-09-27 12 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT04017338
Transplantation Using Hepatitis C Positive Donors, A Safety Trial
Not yet reported Jordan Feld 40 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Lung Transplant Infection, Heart Transplant Infection, Kidney Transplant Infection, Kidney Pancreas Infection, Hepatitis CView official trial listing → -
Completed NCT NCT04056169
Comparison of High-dose Rosuvastatin Versus Low-dose Rosuvastatin Plus Ezetimibe on Carotid Plaque Inflammation in Patients With Acute Coronary Syndrome
Not yet reported Yuhan Corporation 50 participants Est. completion 2019-07-23 2 sites Stand-aloneOther conditions: Acute Coronary Syndrome, Carotid Atherosclerotic Plaque With InflammationView official trial listing → -
Completed NCT NCT04061824
Clinical Study to Evaluate Adherence Improvement Fixed-dose Combination of Olostar Tab. in Patients With Hypertension and Dyslipidemia
Not yet reported Yonsei University 150 participants Est. completion 2018-12-20 1 siteOther conditions: Hypertension, DyslipidemiasView official trial listing → -
Completed NCT NCT04074551
A Phase 3 Study to Compare the Efficacy and Safety of Co-administered HGP0608, HGP0904 and HCP1306 Versus HCP1701 in Patients With Hypertension and Dyslipidemia
Not yet reported Hanmi Pharmaceutical Company Limited 145 participants Est. completion 2020-03-17 1 siteOther conditions: Hypertension, DyslipidemiasView official trial listing → -
Completed NCT NCT04080310
Efficacy and Safety of Combination Therapy of Moderate-intensity Statin and Ezetimibe Compared to High-intensity Statin
Not yet reported Seoul National University Bundang Hospital 270 participants Est. completion 2019-09-17 2 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT04081844
A Study to Evaluate the Pharmacokinetic and Pharmacodynamic Interactions Between HGP0904, HGP0608, and HCP1306 in Healthy Male Subjects.
Not yet reported Hanmi Pharmaceutical Company Limited 31 participants Est. completion 2018-06-28 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT04158076
Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan/Amlodipine
Not yet reported Addpharma Inc. 131 participants Est. completion 2021-01-14 1 site Stand-aloneOther conditions: Hypercholesterolemia, HypertensionView official trial listing → -
Status unknown NCT NCT04161001
Clinical Trail to Evaluate the Efficacy and Safety of DWJ1451
Not yet reported Daewoong Pharmaceutical Co. LTD. 237 participants Est. completion 2022-02-02 1 site Stand-aloneOther conditions: Hypertension, DyslipidemiaView official trial listing → -
Completed NCT NCT04173403
A Long-term Study of AK102 in Patients With Hypercholesterolemia
Not yet reported Akeso 796 participants Est. completion 2023-02-17 1 site Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT04173793
A Study of PCSK9 Inhibitor AK102 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)
Not yet reported Akeso 109 participants Est. completion 2022-09-26 2 sites Stand-aloneOther conditions: Heterozygous Familial HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT04185090
To Evaluate the Pharmacokinetic/Pharmacodynamic Interactions and Safety Between ID1801 and ID1803 in Healthy Male Adults
Not yet reported IlDong Pharmaceutical Co Ltd 30 participants Est. completion 2020-04 Stand-aloneOther conditions: Hypertension, DyslipidemiasView official trial listing → -
Completed NCT NCT04289649
K-924 Phase III Confirmatory Study
Not yet reported Kowa Company, Ltd. 293 participants Est. completion 2020-11-21 3 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT04289662
K-924 Phase III Long Term Study
Not yet reported Kowa Company, Ltd. 110 participants Est. completion 2021-08-07 13 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Withdrawn NCT NCT04303377
Early Treatment With Evolocumab in Patients With ST-elevation Myocardial Infarction
Not yet reported Fondazione IRCCS Policlinico San Matteo di Pavia Est. completion 2020-07-24 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT04322266
A Study to Compare the Pharmacokinetics, Safety and Tolerability Between Fixed-Dose Combination and Co-Administration of HGP0904, HGP0608 and HCP1306 Tablets in Healthy Male Subjects.
Not yet reported Hanmi Pharmaceutical Company Limited 61 participants Est. completion 2019-02-13 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT04358432
A Study of PCSK9 Inhibitor AK102 in Patients With Hypercholesterolemia
Not yet reported Akeso 262 participants Est. completion 2021-02-25 2 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT04369664
CHOlesterol Lowering and Residual Risk in Type 2 Diabetes
Not yet reported NYU Langone Health 151 participants Est. completion 2023-10-19 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT04397653
Evolocumab Plus Ezetimibe in High Risk Haemodialized Statin Intolerant Patients
Not yet reported Policlinico Casilino ASL RMB 50 participants Est. completion 2020-12-14 1 site Stand-aloneChronic kidney disease Other conditions: HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT04433533
Compare the Efficacy and Safety of Rosuvastatin/Ezetimibe Combination Therapy Versus Rosuvastatin Monotherapy in Korean Patients With Left Ventricular Diastolic Dysfunction and Hyperlipidemia
Not yet reported Yonsei University 200 participants Est. completion 2023-12 1 site Stand-aloneOther conditions: Left Ventricular Diastolic Dysfunction, HyperlipidemiasView official trial listing → -
Status unknown NCT NCT04455581
A Study to Determine the Safety, Tolerability, and Efficacy of SHR-1209 in Patients With Familial Hypercholesterolemia
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 8 participants Est. completion 2021-08-31 Stand-aloneOther conditions: Familial HypercholesterolemiaView official trial listing → -
Active, not recruiting NCT NCT04508907
A Study to Evaluate Preemptive Therapy in Hepatitis C (HCV) Organ Transplant Recipients
Not yet reported Mayo Clinic 200 participants Est. completion 2026-11-01 1 siteOther conditions: Hepatitis C, Kidney Transplant; Complications, Heart Transplant InfectionView official trial listing → -
Active, not recruiting NCT NCT04579367
Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company 5000 participants Est. completion 2026-10-30 443 sitesOther conditions: Hypercholesterolemia, Mixed DyslipidemiaView official trial listing → -
Completed NCT NCT04584736
To Evaluate the Efficacy and Safety in Patients With Primary Hypercholesterolemia
Not yet reported JW Pharmaceutical 283 participants Est. completion 2020-10-12 1 site Stand-aloneOther conditions: Primary HypercholesterolemiaView official trial listing → -
Status unknown NCT NCT04589351
Kidney Fat in Type 2 Diabetes and the Effects of Ezetimibe
Not yet reported Steno Diabetes Center Copenhagen 60 participants Est. completion 2022-05 1 siteType 2 diabetesChronic kidney diseaseView official trial listing → -
Completed NCT NCT04626973
Effects of Ezetimibe Combination Therapy for Patients With Atherosclerotic Cardiovascular Disease; Randomized Comparison of LDL-cholesterol Targeting <70 Versus <55mg/dL; Ez-PAVE Trial
Not yet reported Yonsei University 3048 participants Est. completion 2025-09-24 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT04638400
Anti-inflammatory Effects of Simvastatin
Not yet reported paresh Dandona 10 participants Est. completion 2021-11-01 1 siteOther conditions: Inflammation, Atherosclerosis, HypercholesterolemiaView official trial listing → -
Completed NCT NCT04643093
Compare the Efficacy and Safety of 1PC111 With Pitavastatin and Ezetimibe in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia
Not yet reported Orient Pharma Co., Ltd. 390 participants Est. completion 2021-10-05 34 sitesOther conditions: Primary Hypercholesterolemia, Mixed DyslipidemiasView official trial listing → -
Active, not recruiting NCT NCT04656028
Genetic Testing and Motivational Counseling for FH
Not yet reported National Medical Research Center for Therapy and Preventive Medicine 180 participants Est. completion 2025-03-30 1 site Stand-aloneOther conditions: Hypercholesterolemia, Familial, Hypercholesterolemia, Familial, 1, Hypercholesterolemia, Familial, 2, Hypercholesterolemia, Familial, 3, Hypercholesterolemia, Familial, 4, Hypercholesterolemia, Familial, 4, Autosomal Recessive, Familial Hypercholesterolemia With Hyperlipemia, Hypercholesterolemia, Autosomal Dominant, Type B, Hypercholesterolemia, Autosomal Dominant, Hypercholesterolemia, Autosomal Dominant, 3, Apolipoprotein B-100, Familial Defective, Genetic Testing, Motivational Interviewing, Therapeutic Adherence, Therapeutic Adherence and Compliance, Treatment Adherence, Medication Adherence, Treatment Adherence and Compliance, Patient Adherence, Compliance, Patient Compliance, Familial Hypercholesterolemia, Familial Hypercholesterolemia - Heterozygous, Adherence, Patient, Adherence, Medication, AdherenceView official trial listing → -
Status unknown NCT NCT04659070
To Evaluate the Efficacy and Safety of Co-administrated Ezetimibe/Rosuvastatin and Telmisartan in Patients With Essential Hypertension and Primary Hypercholesterolemia
Not yet reported Hanlim Pharm. Co., Ltd. 156 participants Est. completion 2022-05-19 1 site Stand-aloneOther conditions: Primary Hypercholesterolemia, HypertensionView official trial listing → -
Status unknown NCT NCT04659525
Evolocumab Plus Ezetimibe in Haemodialized Statin-intolerant Patients With Hypercholesterolemia
Not yet reported Policlinico Casilino ASL RMB 50 participants Est. completion 2021-12-30 1 site Stand-aloneChronic kidney disease Other conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT04669041
A Study to Evaluate the Efficacy and the Safety of Single Pill Combination (SPC) Ezetimibe/Rosuvastatin in Chinese Adult Patients With Primary Hypercholesterolemia Not Adequately Controlled on Statin Therapy
Not yet reported Sanofi 305 participants Est. completion 2022-06-15 40 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT04700436
Efficacy and Safety of EzetimiBe/Rosuvastatin in Diabetic Dislipidemia With Hypertriglyceridaemia
Not yet reported Seoul National University Hospital 146 participants Est. completion 2024-02-13 26 sites Stand-aloneType 2 diabetes Other conditions: Endocrine System Diseases, Nutritional and Metabolic Diseases, DyslipidemiasView official trial listing → -
Status unknown NCT NCT04701242
Ezetimibe Utilization Early After Acute Myocardial Infarction, "EzAMI Trial"
Not yet reported Cairo University 500 participants Est. completion 2025-12 1 siteCardiovascular disease Other conditions: DyslipidemiasView official trial listing → -
Status unknown NCT NCT04719221
Impact of Evolocumab as an Additional Lipid-lowering Therapy to Changes in Lipid Core Burden Index of Non-culprit Vulnerable Plaque in Patients Who Underwent Percutaneous Coronary Intervention for the Acute Coronary Syndrome
Not yet reported Korea University Anam Hospital 60 participants Est. completion 2024-12 1 siteOther conditions: Clinical Trial, Acute Coronary SyndromeView official trial listing → -
Status unknown NCT NCT04737408
Influence of Intensive Lipid-lowering on FFRCT (The FLOW-PROMOTE Study)
Not yet reported Bjarne Linde Noergaard 120 participants Est. completion 2023-08 3 sitesCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT04755413
The Precision CAD Trial
Not yet reported Emory University 276 participants Est. completion 2028-12 5 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT04770389
Randomized Study of Obicetrapib in Combination With Ezetimibe
Not yet reported NewAmsterdam Pharma 112 participants Est. completion 2021-06-30 9 sites Stand-aloneOther conditions: Dyslipidemias, High Cholesterol, HypercholesterolemiaView official trial listing → -
Completed NCT NCT04807400
Study in Primary Care Evaluating Inclisiran Delivery Implementation + Enhanced Support
Not yet reported Novartis Pharmaceuticals 892 participants Est. completion 2023-01-13 17 sites Stand-aloneCardiovascular disease Other conditions: Elevated Low Density Lipoprotein CholesterolView official trial listing → -
Status unknown NCT NCT04814589
Bioequivalence of Ezetimibe Tablets in Healthy Subjects
Not yet reported Cao Yu 96 participants Est. completion 2021-07-31 1 site Stand-aloneOther conditions: Therapeutic EquivalencyView official trial listing → -
Completed NCT NCT04826354
Effects of Statin for Elderly Patients With Atherosclerotic Cardiovascular Disease
Not yet reported Korea University Anam Hospital 582 participants Est. completion 2023-06-28 2 sitesOther conditions: Atheroscleroses, CoronaryView official trial listing → -
Completed NCT NCT04829149
Statin Monotherapy and Rosuzet Tab.(Rosuvastatin/Ezetimibe) Administration in Patients With Dyslipidemia in Korea
Hanmi Pharmaceutical Company Limited 5717 participants Est. completion 2019-08-29 1 siteOther conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT04844996
Antilipidemic Ezetimibe Induces Regression of Endometriotic Explants in a Rat Model of Endometriosis
Not yet reported Mersin University 18 participants Est. completion 2021-01-31 1 site Stand-aloneOther conditions: EndometriosisView official trial listing → -
Active, not recruiting NCT NCT04862260
Cholesterol Disruption in Combination With the Standard of Care in Patients With Advanced Pancreatic Adenocarcinoma
Not yet reported CHU de Quebec-Universite Laval 3 participants Est. completion 2026-12-31 2 sites Stand-aloneOther conditions: Pancreatic Ductal Adenocarcinoma, Pancreatic Cancer, Pancreas Cancer, Metastatic CancerView official trial listing → -
Completed NCT NCT04862962
Study to Evaluate the Safety of the Fixed-dose Combination Rosuvastatin/Ezetimibe for Patients With Dyslipidaemia
Laboratorios Silanes S.A. de C.V. 120 participants Est. completion 2022-02-15 1 siteOther conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT04895059
Study of no Pharmacokinetic Interaction Between Rosuvastatin 20mg and Ezetimibe10mg, Fixed Dose vs Individual Components
Not yet reported Laboratorios Silanes S.A. de C.V. 36 participants Est. completion 2018-01-22 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT04895098
Statin Monotherapy or Statins in Combination With Ezetimibe in Patients for Prevention of CVD
Akrikhin 1000 participants Est. completion 2022-07-08 31 sitesCardiovascular disease Other conditions: Lipid Metabolism DisordersView official trial listing → -
Status unknown NCT NCT04900155
Evaluation of the Effect of Long-term Lipid-lowering Therapy in STEMI Patients With Coronavirus Infection COVID-19
Not yet reported Penza State University 45 participants Est. completion 2024-12 1 siteOther conditions: STEMI, Covid19, NSTEMIView official trial listing → -
Status unknown NCT NCT05080140
Investigate the Effect of Ezetimibe, Simvastatin, and Omega 3- Fatty Acids on Dyslipidemia Patients: a Pharmacokinetics Based Study
Misr University for Science and Technology 3 participants Est. completion 2022-03-20 1 siteOther conditions: Hyperlipidemia; MixedView official trial listing → -
Status unknown NCT NCT05081336
Low-density Lipoprotein Cholesterol Reduction With State-of-the-art Therapy in Secondary Prevention and Major Cardiovascular Adverse Events: Republic of Srpska Registry
University Clinical Centre of Republic of Srpska 500 participants Est. completion 2023-03 1 siteOther conditions: Acute Coronary Syndrome, DyslipidemiasView official trial listing → -
Active, not recruiting NCT NCT05088759
Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density Lipoprotein Management
Not yet reported Brigham and Women's Hospital 400 participants Est. completion 2026-06-30 1 site Stand-aloneCardiovascular disease Other conditions: Hyperlipemia, MixedView official trial listing → -
Completed NCT NCT05095896
The Serum Lipid Profiles in ITP: a Retrospective Study
Ming Hou 457 participants Est. completion 2020-12-01 1 siteOther conditions: Immune ThrombocytopeniaView official trial listing → -
Completed NCT NCT05131997
A Study to Evaluate the Efficacy and Safety of AD-221 and AD-221A
Not yet reported Addpharma Inc. 290 participants Est. completion 2022-06-08 1 siteOther conditions: Primary HypercholesterolemiaView official trial listing → -
Completed NCT NCT05184530
In-hospital Initiation of PCSK9 Inhibitor in Patients With Acute Myocardial Infarction
First Affiliated Hospital Xi'an Jiaotong University 7556 participants Est. completion 2021-12Other conditions: Coronary DiseaseView official trial listing → -
Completed NCT NCT05255094
A Study to Evaluate the Efficacy and Safety of AK102 in Patients With Hyperlipidemia
Not yet reported Akeso 464 participants Est. completion 2022-06-22 1 site Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT05255458
A Study to Evaluate the Long-term Efficacy and Safety of AK102 in Patients With Hyperlipidemia
Not yet reported Akeso 122 participants Est. completion 2023-01-09 1 site Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT05260411
A Study to Evaluate the Efficacy and Safety of AK102 Q6W in Patients With Hyperlipidemia
Not yet reported Akeso 246 participants Est. completion 2022-12-19 2 sites Stand-aloneOther conditions: HyperlipidemiaView official trial listing → -
Status unknown NCT NCT05263778
Cholesterol Lowering Via Bempedoic Acid/Ezetimibe, an ACL-Inhibiting Regimen in Acute Coronary Syndrome Study
Not yet reported Kaiser Permanente 500 participants Est. completion 2023-12 1 siteCardiovascular disease Other conditions: NSTEMI, STEMIView official trial listing → -
Completed NCT NCT05266586
Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapy
Not yet reported NewAmsterdam Pharma 119 participants Est. completion 2022-09-08 16 sites Stand-aloneOther conditions: Dyslipidemias, High Cholesterol, HypercholesterolemiaView official trial listing → -
Active, not recruiting NCT NCT05361421
Effect of Intensive LDL-cholesterol Targeting for Elderly Patients With Cardiovascular Disease: I-OLD Trial
Not yet reported Yonsei University 1200 participants Est. completion 2027-10-15 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT05368545
Influence of Lipid Lowering on Impaired Coronary Flow
Not yet reported Aarhus University Hospital 109 participants Est. completion 2024-04-17 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT05372380
A Study to Evaluate Drug-drug Interactions Between BR1017-1 and BR1017-2 in Healthy Volunteers
Not yet reported Boryung Pharmaceutical Co., Ltd 32 participants Est. completion 2022-06-30 1 siteOther conditions: Hypertension, HypercholesterinemiaView official trial listing → -
Status unknown NCT NCT05381870
Bioequivalence Study of Ezetimibe Tablets Under Fasting Conditions in Healthy Subjects
Not yet reported The Affiliated Hospital of Qingdao University 48 participants Est. completion 2022-12-30 Stand-aloneOther conditions: Pharmacokinetics, SafetyView official trial listing → -
Active, not recruiting NCT NCT05462262
Intensive Lipid-lowering for Plaque and Major Adverse Cardiovascular Events in Low to Intermediate 10-year ASCVD Risk Population
Not yet reported Chinese Academy of Medical Sciences, Fuwai Hospital 2900 participants Est. completion 2029-08 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT05481385
Bioequivalence Study of Ezetimibe Tablets Under Fed Conditions in Healthy Subjects
Not yet reported The Affiliated Hospital of Qingdao University 48 participants Est. completion 2022-12-30 1 site Stand-aloneOther conditions: Pharmacokinetics, SafetyView official trial listing → -
Completed NCT NCT05543122
Drug Concentrations in Breast Milk and Prediction of Blood Levels of the Breastfed Infants
The Hospital for Sick Children 39 participants Est. completion 2024-03-31 1 siteOther conditions: Breast FeedingView official trial listing → -
Completed NCT NCT05546398
SurveY Followed by a Retrospective Chart Review to Describe the Key Factors Leading to Physician's Decision to Treat Patients at High and Very High Cardiovascular Risk With hyperchOlesterolemia or Mixed Dyslipidemia With NUSTENDI®
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company 500 participants Est. completion 2022-11-17 63 sitesOther conditions: Hypercholesterolemia, Mixed DyslipidemiaView official trial listing → -
Completed NCT NCT05559606
An OS to Evaluate the Safety & Efficacy of Fixed Dose Combination Therapy With Atorvastatin and Ezetimibe
Boryung Pharmaceutical Co., Ltd 1839 participants Est. completion 2025-07-30 1 siteOther conditions: Primary HypercholesterolemiaView official trial listing → -
Enrolling by invitation NCT NCT05579626
Comparison of Low-Intensity Statin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus (PROVE-DM)
Not yet reported Seung-Whan Lee, M.D., Ph.D. 4000 participants Est. completion 2030-12-31 31 sitesCardiovascular disease Other conditions: Pre DiabetesView official trial listing → -
Not yet recruiting NCT NCT05587621
Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target)
Not yet reported Jena University Hospital 300 participants Est. completion 2026-12-31 10 sitesCardiovascular disease Other conditions: LDL-cholesterolView official trial listing → -
Status unknown NCT NCT05613400
Statin and Bone Health
Not yet reported The University of Hong Kong 240 participants Est. completion 2025-06-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05614765
Evaluation of Dyslipidemia Management After Statin and Ezetimibe Complex Treatment
Daewoong Pharmaceutical Co. LTD. 18000 participants Est. completion 2025-12-31 1 siteOther conditions: DyslipidemiasView official trial listing → -
Status unknown NCT NCT05624658
Effect of Combined Lipid-lowering Therapy on Atherosclerotic Plaque Vulnerability in Patients With ACS
Not yet reported Samara Regional Cardiology Dispensary 200 participants Est. completion 2024-05 1 siteOther conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT05661552
Effect of Early Initiation of Evolocumab on Lipid Profiles Changes in Patients With ACS Undergoing PCI
Not yet reported Yonsei University 108 participants Est. completion 2025-02-05 1 site Stand-aloneOther conditions: Low-Density-Lipoprotein-Type [LDL] HyperlipoproteinemiaView official trial listing → -
Completed NCT NCT05681247
Bioavailability and Bioequivalence of Ezetimibe Tablets in Healthy Subjects
Not yet reported The Affiliated Hospital of Qingdao University 59 participants Est. completion 2018-03-07 1 site Stand-aloneOther conditions: HyperlipidemiasView official trial listing → -
Completed NCT NCT05761444
Effectiveness and Safety Study of Early add-on of Ezetimibe With Atorvastatin in Very High-risk Patients
Not yet reported Organon and Co 137 participants Est. completion 2024-10-15 7 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT05763875
Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy.
Not yet reported Novartis Pharmaceuticals 350 participants Est. completion 2024-06-20 42 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT05795517
Study of HSK31679 in Subjects With Hypercholesterolemia With Nonalcoholic Fatty Liver Disease(NAFLD)
Not yet reported Haisco Pharmaceutical Group Co., Ltd. 210 participants Est. completion 2024-03-01 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Withdrawn NCT NCT05798390
Treatment With Bempedoic Acid And/Or Its Fixed-dose Combination With Ezetimibe in Routine Clinical Practice in Patients With Primary Hypercholesterolemia Or Mixed Dyslipidemia
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company Est. completion 2026-04-01Other conditions: Primary Hypercholesterolemia, Mixed DyslipidemiaView official trial listing → -
Status unknown NCT NCT05884502
A Multicenter Study to Evaluate the Effect of High Dose Rosuvastatin Versus Rosuvastatin and Ezetimibe in Stroke
Not yet reported Korea University Anam Hospital 330 participants Est. completion 2024-12-31 3 sites Stand-aloneCardiovascular disease Other conditions: DyslipidemiasView official trial listing → -
Active, not recruiting NCT NCT05889143
A Study to Evaluate the Efficacy and Safety of CREZET Tablet
Daewoong Pharmaceutical Co. LTD. 15000 participants Est. completion 2026-03-01 1 siteOther conditions: DyslipidemiasView official trial listing → -
Active, not recruiting NCT NCT05910476
Comparative Study of Rosuvastatin/Ezetimib 20/10 mg and Atovastatin/Ezetimib 40/10 mg (TOLERANT Trial)
Not yet reported Yonsei University 200 participants Est. completion 2026-09-22 1 siteCardiovascular disease Other conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT05930028
A Study to Evaluate the Efficacy and Safety of BR1017A and BR1017B Combination Therapy in Essential Hypertension Patients With Primary Hypercholesterolemia
Not yet reported Boryung Pharmaceutical Co., Ltd 148 participants Est. completion 2024-09-05 1 site Stand-aloneOther conditions: Essential Hypertension, Primary HypercholesterolemiaView official trial listing → -
Completed NCT NCT05970679
Clinical Trial to Evaluate the Efficacy and Safety of DW1125 and DW1125A
Not yet reported Daewon Pharmaceutical Co., Ltd. 252 participants Est. completion 2023-04-13 1 site Stand-aloneOther conditions: Hypercholesterolemia, DyslipidemiaView official trial listing → -
Completed NCT NCT05974345
In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease
Novartis Pharmaceuticals 204691 participants Est. completion 2023-12-15 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT06005597
Study of Obicetrapib & Ezetimibe Fixed Dose Combination on Top of Maximum Tolerated Lipid-Modifying Therapies
Not yet reported NewAmsterdam Pharma 407 participants Est. completion 2024-10-16 45 sites Stand-aloneCardiovascular disease Other conditions: Dyslipidemias, Hypercholesterolemia, Familial Hypercholesterolemia, High CholesterolView official trial listing → -
Completed NCT NCT06021951
Milk-Only Lactation Study to Evaluate the Concentration of Bempedoic Acid and Bempedoic Acid/Ezetimibe Fixed Combination Drug Product (FCDP) in the Breast Milk of Healthy Lactating Women
Not yet reported Esperion Therapeutics, Inc. 16 participants Est. completion 2024-03-22 1 site Stand-aloneOther conditions: Healthy Lactating WomenView official trial listing → -
Completed NCT NCT06050291
Investigating the Effect of Food on the Bioavailability of a Fixed Dose Combination of Obicetrapib and Ezetimibe
Not yet reported NewAmsterdam Pharma 28 participants Est. completion 2024-04-07 1 site Stand-aloneOther conditions: Healthy Volunteer StudyView official trial listing → -
Not yet recruiting NCT NCT06096909
Early Initiation of Tafolecimab for Patients With Acute Coronary Syndromeundergoing Percutaneous Coronary Intervention in Chinese Population
Not yet reported China National Center for Cardiovascular Diseases 3684 participants Est. completion 2027-11-01Other conditions: Acute Coronary Syndrome, Non ST Segment Elevation Acute Coronary SyndromeView official trial listing → -
Completed NCT NCT06225635
A Phase 1 Study to Evaluate the Safety and Pharmacokinetics of Ezerosu Tab
Not yet reported Shin Poong Pharmaceutical Co. Ltd. 60 participants Est. completion 2022-03-07 1 site Stand-aloneOther conditions: HyperlipidemiasView official trial listing → -
Withdrawn NCT NCT06280976
Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP)
Not yet reported University of Louisville Est. completion 2025-01-01 1 site Stand-aloneCardiovascular disease Other conditions: Atherosclerosis, Heart AttackView official trial listing → -
Active, not recruiting NCT NCT06305559
A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque
Not yet reported NewAmsterdam Pharma 300 participants Est. completion 2028-02 1 site Stand-aloneCardiovascular disease Other conditions: Lipidemia, Plaque, AtheroscleroticView official trial listing → -
Active, not recruiting NCT NCT06317051
Optimising Metabolic Management for People With Human Immunodeficiency Virus (HIV) on Integrase Based Antiretroviral Therapy (ART)
Not yet reported Kirby Institute 300 participants Est. completion 2027-12 10 sitesOther conditions: HIV Infections, Weight GainView official trial listing → -
Status unknown NCT NCT06381947
Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients
Not yet reported University of Salerno 130 participants Est. completion 2025-06-30 Stand-aloneCardiovascular disease Other conditions: Dyslipidemias, Statin Adverse Reaction, Lipid Metabolism DisordersView official trial listing → -
Completed NCT NCT06431763
A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.
Not yet reported Novartis Pharmaceuticals 402 participants Est. completion 2026-01-02 55 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT06450366
A Study to Evaluate the Efficacy and Safety of Enlicitide (MK-0616, Oral PCSK9 Inhibitor) Compared With Ezetimibe or Bempedoic Acid or Ezetimibe and Bempedoic Acid in Adults With Hypercholesterolemia (MK-0616-018/CORALreef AddOn)
Not yet reported Merck Sharp & Dohme LLC 301 participants Est. completion 2025-03-28 35 sites Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT06547359
A Study to Evaluate Drug-Drug Interactions of Obicetrapib Tablets and Ezetimibe Tablets in Healthy Adult Subjects
Not yet reported NewAmsterdam Pharma 94 participants Est. completion 2024-11-12 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT06567418
Retrospective Analysis of the Effect of In-hospital Initiation of PCSK9i on Clinical Outcomes in Chinese ACS Patients
Yun Dai Chen 10000 participants Est. completion 2025-01-31 1 siteOther conditions: Acute Coronary SyndromeView official trial listing → -
Status unknown NCT NCT06578676
To Evaluate the Safety and Pharmacokinetic Interaction Between HODO-22251 and HODO-22252 in Healthy Adults
Not yet reported Hyundai Pharm 56 participants Est. completion 2024-11-30 1 site Stand-aloneType 2 diabetes Other conditions: DyslipidemiasView official trial listing → -
Enrolling by invitation NCT NCT06646354
To Evaluate the Efficacy and Safety of Co-administrated HODO-2224-1 and HODO-2224-2 in Patients With Essential Hypertension and Primary Hypercholesterolemia
Not yet reported Hyundai Pharm 125 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Hypertension, Primary HypercholesterolaemiaView official trial listing → -
Completed NCT NCT06647238
Evaluation of Pharmacist Interventions in Lipid Management for Secondary Prevention
Not yet reported Wake Forest University Health Sciences 80 participants Est. completion 2025-05-27 1 site Stand-aloneCardiovascular disease Other conditions: HyperlipidemiaView official trial listing → -
Completed NCT NCT06740552
Evolocumab in Patients With Multivessel Coronary Disease After Acute Myocardial Infarction: A Target Trial Emulation
Shanghai Zhongshan Hospital 1862 participants Est. completion 2025-10-31 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT06742853
A Study to Investigate the Pharmacokinetics, Safety, Tolerability, and Efficacy of AZD0780 With Ezetimibe Combinations in Healthy Adults With Elevated LDL-C.
Not yet reported AstraZeneca 81 participants Est. completion 2025-10-29 3 sites Stand-aloneOther conditions: DyslipidemiaView official trial listing → -
Not yet recruiting NCT NCT06821711
Optimal LDL-C Target in High-risk Patients After PCI
Not yet reported Xijing Hospital 12000 participants Est. completion 2029-08-15 1 site Stand-aloneOther conditions: Chronic Coronary Syndrome, Acute Coronary Syndromes, Percutaneous Coronary Intervention, High Risk PatientView official trial listing → -
Not yet recruiting NCT NCT06854523
Assessing Coronary Non-Culprit Plaque Early with Start of PCSK9 Inhibitors in Acute Myocardial Infarction (ACCESS-AMI)
Not yet reported Yun Dai Chen 300 participants Est. completion 2026-12-31 2 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT06866509
To Investigate Blood Lipid Changes and Safety After Litorvazet® Tablets in Dyslipidemia Patients
Daewoong Pharmaceutical Co. LTD. 3000 participants Est. completion 2024-02-28 1 siteOther conditions: DyslipidemiaView official trial listing → -
Not yet recruiting NCT NCT07084259
Single Dose PCSK9 Inhibitor to Improve Cardiovascular Outcomes After PCI: A Pilot Study
Not yet reported Hanyang University Seoul Hospital 352 participants Est. completion 2030-07Cardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07174375
PCSK9 Inhibitors in Acute Ischemic Stroke Patients Undergoing Endovascular Therapy
Not yet reported, Not yet reported Nanfang Hospital, Southern Medical University 478 participants Est. completion 2027-12-15 12 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT07182383
Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and Rosuvastatin
Not yet reported Daiichi Sankyo 58 participants Est. completion 2025-11-24 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT07201545
Evaluating Bioequivalence of a Fixed Dose Combination Versus Tablets of Bempedoic Acid / Ezetimibe and Rosuvastatin
Not yet reported Daiichi Sankyo 58 participants Est. completion 2025-12-10 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Active, not recruiting NCT NCT07219602
A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome
Not yet reported NewAmsterdam Pharma 300 participants Est. completion 2028-06 55 sites Stand-aloneType 2 diabetesMetabolic syndrome Other conditions: LipidemiaView official trial listing → -
Completed NCT NCT07235189
A Study Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and Atorvastatin
Not yet reported Daiichi Sankyo 58 participants Est. completion 2026-01-28 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT07255820
Dual vs Triple Lipid-Lowering Therapy in Type 2 Diabetes Mellitus Patients With Elevated LDL Cholesterol
Not yet reported Bahria University 126 participants Est. completion 2026-06-30 1 siteType 2 diabetes Other conditions: Hypercholesterolemia / Elevated LDL CholesterolView official trial listing → -
Not yet recruiting NCT NCT07256171
COAST Study - Cholesterol Optimization After Stroke
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 500 participants Est. completion 2026-12-31Cardiovascular disease Other conditions: Cerebral HemorrhageView official trial listing → -
Completed NCT NCT07268625
Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid / Ezetimibe, and Atorvastatin
Not yet reported Daiichi Sankyo 58 participants Est. completion 2026-02-24 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Not yet recruiting NCT NCT07341958
INtensive liPid-lowering Therapy for Acute High-risk IntracRanial or Extracranial atheroSclerosis -II (INSPIRES-2)
Not yet reported Beijing Tiantan Hospital 242 participants Est. completion 2027-08-30 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07432516
Optimal Antiplatelet and Lipid Therapy in ACS With DES: OPACT Trial
Not yet reported Yonsei University 4400 participants Est. completion 2033-06 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07440381
triPle Oral thERapy With Bempedoic Acid vs uSual Care in Early Lipid Management of Patients With acUte coronAry synDromE
Not yet reported Heart Care Foundation 600 participants Est. completion 2027-08 35 sites Stand-aloneOther conditions: Acute Coronary Syndromes, Secondary Prevention, LipidsView official trial listing → -
Active, not recruiting NCT NCT07442630
Long-term Comparison of Pitavastatin/Ezetimibe and Pitavastatin in Patients With Hypercholesterolemia and Elevated Triglycerides
Not yet reported JW Pharmaceutical 88 participants Est. completion 2026-11-30 1 site Stand-aloneOther conditions: HypercholesterolemiaView official trial listing → -
Completed NCT NCT07445542
Efficacy and Safety of Pitavastatin/Ezetimibe After Switching From Statin Monotherapy to Pitavastatin/Ezetimibe in Patients With Hypercholesterolemia
JW Pharmaceutical 6927 participants Est. completion 2025-05-13 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Not yet recruiting NCT NCT07474649
A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events
Not yet reported Daiichi Sankyo 103 participants Est. completion 2028-10-02 12 sites Stand-aloneOther conditions: Coronary Atherosclerosis, Mixed Dyslipidemia, HypercholesterolemiaView official trial listing → -
Completed NCT NCT07489183
A Prospective, Open, Observational Study to Confirm the Lipid-lowering Effect, Changes in Glucose Metabolism, and Safety After 6 Months of Administration of Atostazet to Hypercholesterolemic Patients 65 Years of Age or Older
Dong Wha Pharmaceutical Co. Ltd. 641 participants Est. completion 2023-09-07 1 siteOther conditions: HypercholesterolemiaView official trial listing → -
Not yet recruiting NCT NCT07508254
Triple vs Dual Lipid-Lowering Therapy for LDL-C Reduction in Acute Coronary Syndrome
Not yet reported Punjab Institute of Cardology 120 participants Est. completion 2026-10-31 1 site Stand-aloneOther conditions: Acute Coronary Syndromes (ACS), HypercholesterolemiaView official trial listing → -
Not yet recruiting NCT NCT07515560
Efficacy and Safety of Baroezet Tablet in Korean Patients With Dyslipidemia: A Prospective Observational Study
Daewoong Pharmaceutical Co. LTD. 12000 participants Est. completion 2027-12-31 1 siteOther conditions: DyslipidemiaView official trial listing → -
Completed NCT NCT07564726
Efficacy and Safety of Ezetimibe/Rosuvastatin and Amlodipine Patients With High Blood Pressure and High Cholesterol
Not yet reported Celltrion Pharm, Inc. 163 participants Est. completion 2024-02-13 21 sites Stand-aloneOther conditions: Hypertension, HypercholesterolemiaView official trial listing → -
Not yet recruiting NCT NCT07605130
Efficacy and Safety Study of Digital Cognitive Training and PCSK9 Inhibitor-Enhanced Lipid-lowering Strategy in Patients With Intracranial Atherosclerotic Stenosis: A 2x2 Factorial, Randomized, Parallel-Group, Multicenter Trial
Not yet reported Peking Union Medical College Hospital 440 participants Est. completion 2029-07-31 1 site Stand-aloneOther conditions: Intracranial Arteriosclerosis, Cognitive ImpairmentView official trial listing → -
Not yet recruiting NCT NCT07615296
Target-Oriented Strategy of Ultra-Low LDL-C (<1.0 vs. 1.0-1.39 mmol/L) in Extreme-High-Risk ASCVD Patients: Clinical Benefit, Safety and Cost-Effectiveness Assessment
Not yet reported Beijing Anzhen Hospital 6000 participants Est. completion 2031-12-31 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Active, not recruiting NCT NCT07622433
A Phase I, Cross-over Study Comparing the Relative Bioavailability of Laroprovstat Plus Ezetimibe Fixed Combination Drug Products Versus Their Single Therapy Products in Healthy Adults
Not yet reported AstraZeneca 18 participants Est. completion 2026-09-07 1 site Stand-aloneOther conditions: Healthy ParticipantsView official trial listing → -
Not yet recruiting NCT NCT07626840
Livalozet Versus High-intensity Statin in Older Patients With Coronary Artery Disease Undergoing Percutaneous Coronary Intervention
Not yet reported Samsung Medical Center 5000 participants Est. completion 2031-12-31 Stand-aloneOther conditions: Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)View official trial listing → -
Not yet recruiting NCT NCT07674524
Management Strategy of 1L Lorlatinib With Hyperlipidemia in Stage IIIB-IV ALK Positive NSCLC
Sun Yat-sen University 160 participants Est. completion 2029-12-31 1 siteOther conditions: Non-Small Cell Lung Cancer (NSCLC), Hyperlipidemia, ALK Gene Mutation, ALK-positiveView official trial listing → -
Not yet recruiting NCT NCT07684469
Comparative Assessment of Inclisiran on Top of Standard of Care Versus Standard of Care Alone for LDL-C Evaluation in Acute Coronary Syndrome Patients in Saudi Arabia
Not yet reported Novartis Pharmaceuticals 300 participants Est. completion 2028-10-31 Stand-aloneOther conditions: Acute Coronary SyndromeView official trial listing → -
Not yet recruiting NCT NCT07685054
To Evaluate the Renal Protective Effects and Safety of 'Fimasartan and Atorvastatin' or 'Fimasartan, Atorvastatin and Ezetimibe'.
Boryung Pharmaceutical Co., Ltd 12700 participants Est. completion 2029-08-15Other conditions: Essential Hypertension, Primary HypercholesterolemiaView official trial listing → -
Not yet recruiting NCT NCT07752758
Ezetimibe for Arrhythmia Recurrence After AF Ablation
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 120 participants Est. completion 2028-06-30 Stand-aloneOther conditions: Atrial Fibrillation, Post-Catheter Ablation Atrial Arrhythmia RecurrenceView official trial listing → -
Not yet recruiting NCT NCT07784621
A Phase 1 Clinical Trial to Evaluate the Safety and the Pharmacokinetic Drug-Drug Interaction Between HUC2A-752-A and HUC2A-752-B in Healthy Adults
Not yet reported Huons Co., Ltd. 30 participants Est. completion 2027-02 1 site Stand-aloneOther conditions: HypertensionView official trial listing → -
Not yet recruiting NCT NCT07799779
Early Intensive Lipid-Lowering With Inclisiran for Plaque Stabilization in Acute Coronary Syndrome
Not yet reported Seoul National University Bundang Hospital 294 participants Est. completion 2029-09 1 site Stand-aloneOther conditions: Acute Coronary Syndromes (ACS)View official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Ezetimibe, Ezetimibe and Simvastatin
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