About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Exendin-9,39
- Company
- Mayo Clinic
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 6 recruiting
Efficacy results: Not yet reported
6 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Find a Clinical Trial Near Me
See recruiting studies for Exendin-9,39 and check eligibility with the study team.
Trial details
-
Recruiting NCT NCT00992901
Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery
Not yet reported The University of Texas Health Science Center at San Antonio 160 participants Est. completion 2027-08 2 sitesOther conditions: Post Bariatricsurgery, HypoglycemiaView official trial listing → -
Recruiting NCT NCT01803451
Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
Not yet reported The University of Texas Health Science Center at San Antonio 80 participants Est. completion 2027-08 2 sitesOther conditions: Post-bariatric SurgeryView official trial listing → -
Recruiting NCT NCT02823665
The Effects of Bariatric Surgeries on Glucose Metabolism
Not yet reported The University of Texas Health Science Center at San Antonio 200 participants Est. completion 2027-08 2 sitesOther conditions: Post Bariatric Surgery, Gastric Bypass, Sleeve Gastrectomy, Hypoglycemia After Gastric BypassView official trial listing → -
Recruiting NCT NCT06967558
The Role of Islet GLP-1 in the Pathogenesis of Prediabetes
Not yet reported Mayo Clinic 60 participants Est. completion 2028-03-31 1 sitePrediabetesView official trial listing → -
Recruiting NCT NCT07019519
POTS-FLOW: Interplay Between Gut Hormones and Autonomic Postprandial Blood Flow Regulation in Patients With POTS
Not yet reported University of Copenhagen 30 participants Est. completion 2026-09-30 1 siteOther conditions: Postural Orthostatic Tachycardia Syndrome (POTS), HealthyView official trial listing → -
Recruiting NCT NCT07806695
Islet Function in Gestational Diabetes
Not yet reported Mayo Clinic 90 participants Est. completion 2030-12 1 siteOther conditions: Gestational Diabetes MellitusView official trial listing → -
Completed NCT NCT00393445
Exendin(9-39)Amide as a Glucagon-like Peptide-1 (GLP-1) Receptor Antagonist in Humans
Not yet reported Ludwig-Maximilians - University of Munich 6 participants Est. completion 2007-05 1 siteOther conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT00468091
Effects of Exendin(9-39) on Gastroduodenal Motility
Not yet reported Ludwig-Maximilians - University of Munich 10 participants Est. completion 2000-09 1 siteOther conditions: Digestive Physiology, Gastrointestinal Motility, Gastrointestinal Hormones, Glucagon-like Peptide 1, Exendin (9-39)View official trial listing → -
Completed NCT NCT00551590
Effect of Sitagliptin on Incretin Effect in Patients With Type 2 Diabetes Mellitus
Not yet reported Ludwig-Maximilians - University of Munich 24 participants Est. completion 2011-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00571324
Effect of Exendin-(9-39) on Glycemic Control in Subjects With Congenital Hyperinsulinism
Not yet reported, Not yet reported Diva De Leon 9 participants Est. completion 2014-12 1 siteOther conditions: Congenital HyperinsulinismView official trial listing → -
Terminated NCT NCT00835328
Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia
Not yet reported, Not yet reported Diva De Leon 14 participants Est. completion 2017-01-28 1 siteOther conditions: Congenital HyperinsulinismView official trial listing → -
Completed NCT NCT00897676
Effect of Exendin-(9-39) on Fasting Adaptation and Protein Sensitivity
Not yet reported, Not yet reported Diva De Leon 17 participants Est. completion 2017-01 1 siteOther conditions: Congenital HyperinsulinismView official trial listing → -
Completed NCT NCT00980083
GLP-1 - Regulatory Mechanism of Postprandial Glycemia
Not yet reported Ludwig-Maximilians - University of Munich 12 participants Est. completion 2007-12 1 siteOther conditions: Healthy Subjects, Gastric EmptyingView official trial listing → -
Withdrawn NCT NCT01152333
The Role of GLP-1 in Satiety Perception in Humans
Not yet reported University of Washington Est. completion 2016-07 1 siteOther conditions: Appetite Regulation, ObesityView official trial listing → -
Completed NCT NCT01162499
Role of Glucagon-Like Peptide-1 in Postprandial Hypoglycemia
Not yet reported Diva De Leon 7 participants Est. completion 2014-12 1 siteOther conditions: Postprandial HypoglycemiaView official trial listing → -
Completed NCT NCT01181986
The Study of Exenatide Action on Vessel Function in Type 2 Diabetes and Prediabetes
Not yet reported Carl T. Hayden VA Medical Center 76 participants Est. completion 2012-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01281228
The Effect of GLP-1 Receptor Activation on Central Reward and Satiety in Obesity and Diabetes
Not yet reported Amsterdam UMC, location VUmc 48 participants Est. completion 2013-10 1 siteType 2 diabetes Other conditions: Diabetes Mellitus, ObesityView official trial listing → -
Completed NCT NCT01363609
Effects of Glucagon Like Peptide-1(GLP-1) and Liraglutide on Brain Satiety and Reward Circuits and Feeding Behavior in Diabetes
Not yet reported Amsterdam UMC, location VUmc 50 participants Est. completion 2015-01 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT01449019
The Role of Endogenous Glucagon-like Peptide 1 (GLP-1) in Type 2 Diabetes Mellitus (T2DM)
Not yet reported Ludwig-Maximilians - University of Munich 24 participants Est. completion 2010-07 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01579981
The Importance of GLP-1 in Post RYGB Improvement in Glycaemic Control Type 2 Diabetic Subjects
Not yet reported Hvidovre University Hospital 9 participants Est. completion 2012-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01701973
Effect of DPP4 Inhibition on Growth Hormone Secretion
Not yet reported Vanderbilt University 44 participants Est. completion 2017-05 1 siteOther conditions: ObesityView official trial listing → -
Status unknown NCT NCT01729299
Ghrelin Effect on Beta Cell Function in Health and Disease
Not yet reported David Dalessio 30 participants Est. completion 2014-04 2 sitesOther conditions: DiabetesView official trial listing → -
Status unknown NCT NCT01760772
Effect of GLP-1 on Postprandial Lipid Metabolism
Not yet reported David Dalessio 42 participants Est. completion 2015-02 1 siteOther conditions: Heart DiseaseView official trial listing → -
Completed NCT NCT01795144
Incretin Regulation of Insulin Secretion in Monogenic Diabetes
Not yet reported University of Chicago 10 participants Est. completion 2017-03 1 siteOther conditions: Monogenic DiabetesView official trial listing → -
Completed NCT NCT01843855
The Contribution of Incretin Hormones to the Amelioration of Glucose Metabolism After Roux-en-Y Gastric Bypass
Not yet reported Adrian Vella 12 participants Est. completion 2013-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01843881
The Contribution of Incretin Hormones to Post-prandial Glucose Metabolism After Roux-en-Y Gastric Bypass
Not yet reported Adrian Vella 20 participants Est. completion 2013-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01865760
Etiology, Assessment and Treatment of Post-gastric Bypass Severe Hypoglycemia
Not yet reported University of Aarhus 33 participants Est. completion 2016-03 1 siteOther conditions: Obesity, Hypoglycemia, SurgeryView official trial listing → -
Completed NCT NCT01900340
Intestinal Glucagon-like Peptide-1 (GLP-1) and the Physiological Role in Eating in Humans
Not yet reported University Hospital, Basel, Switzerland 12 participants Est. completion 2012-12 1 siteOther conditions: Appetite and General Nutritional DisordersView official trial listing → -
Completed NCT NCT01918566
The Role of Endogenous GLP-1 (Glycolipoprotein) in Regulating Glucose Stimulated Brain Activity
Not yet reported University Hospital, Basel, Switzerland 12 participants Est. completion 2013-03 1 siteOther conditions: Exploratory BehaviorView official trial listing → -
Completed NCT NCT02050074
The Role of Metformin and Colesevelam in Human GLP-1 Secretion
Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2014-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02128581
A Dose-response of the Effects of Exendin-9,39 on GI Symptoms and Food Intake
Not yet reported Mayo Clinic 3 participants Est. completion 2019-07 1 siteOther conditions: Obesity, Diabetes, Roux-en-Y Gastric BypassView official trial listing → -
Completed NCT NCT02170870
Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus
Not yet reported Mayo Clinic 104 participants Est. completion 2017-11-17 1 siteOther conditions: Dyspepsia, Diabetes Mellitus With Gastrointestinal SymptomsView official trial listing → -
Completed NCT NCT02287285
Determinants of Diabetes Remission After Gastric Bypass Surgery
Not yet reported Blandine Laferrere 25 participants Est. completion 2019-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02336659
Influence of Gut Hormones on Food Intake After Roux-en-Y Gastric Bypass Surgery
Not yet reported Hvidovre University Hospital 12 participants Est. completion 2016-06 1 siteOther conditions: Severe ObesityView official trial listing → -
Terminated NCT NCT02550145
Role of GLP-1 in Hyperinsulinemic Hypoglycemia Post-bariatric Surgery
Not yet reported Tracey McLaughlin 10 participants 1 siteOther conditions: HypoglycemiaView official trial listing → -
Completed NCT NCT02639130
GLP-1 Mediating DPP-4 Inhibition in Type 2 Diabetes
Not yet reported Diabeteszentrum Bad Lauterberg im Harz 67 participants Est. completion 2010-01 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT02697253
Mechanisms Underlying Predictors of Success From Obesity Surgery
Not yet reported Icahn School of Medicine at Mount Sinai Est. completion 2021-07-29 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT02746757
Glucagon Like Peptide-1 in Remote Ischemic Conditioning
Not yet reported Karolinska Institutet 12 participants Est. completion 2018-01 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02771574
Efficacy, Tolerability and Pharmacokinetics of Subcutaneous Exendin (9-39) in Patients With Post Bariatric Hypoglycemia
Not yet reported Tracey McLaughlin 19 participants Est. completion 2017-06 1 siteOther conditions: Post Bariatric HypoglycemiaView official trial listing → -
Completed NCT NCT02779075
Exendin-9,39 and Satiety After Bariatric Surgery
Not yet reported Mayo Clinic 29 participants Est. completion 2019-12 1 siteOther conditions: ObesityView official trial listing → -
Terminated NCT NCT02844907
Regulation of Insulin Secretion by the GLP-1 Receptor
Not yet reported VA Office of Research and Development 6 participants Est. completion 2021-12-31 1 siteOther conditions: Insulin SecretionView official trial listing → -
Completed NCT NCT02971631
Gastrectomy, Eating Behaviour and GLP-1
Not yet reported Cambridge University Hospitals NHS Foundation Trust 5 participants Est. completion 2018-09-16 1 siteOther conditions: Gastric Cancer, Dumping SyndromeView official trial listing → -
Completed NCT NCT02996812
Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia
Not yet reported Tracey McLaughlin 9 participants Est. completion 2016-08 1 siteOther conditions: Hyperinsulinemia HypoglycemiaView official trial listing → -
Completed NCT NCT03013296
Delinieation of GIP's Effects During a Meal in Humans Using GIP Receptor Antagonisation (GA-4)
Not yet reported University Hospital, Gentofte, Copenhagen 12 participants Est. completion 2018-09 1 siteOther conditions: Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT03101930
Cardiovascular Effects of GLP-1 Receptor Activation
Not yet reported Vanderbilt University Medical Center 329 participants Est. completion 2021-06-24 1 sitePrediabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT03133741
Inhibition of the Endogenous GIP Response With a GIP Receptor Antagonist
Not yet reported University Hospital, Gentofte, Copenhagen 18 participants Est. completion 2017-07-01 1 siteOther conditions: Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT03241303
Delineation of the Role of Glucagon-like Peptide-1 Signalling in Relation to Increased Carbohydrate Content in the Distal Small Intestines
Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2018-01-01 1 siteOther conditions: Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT03246451
The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D
Not yet reported University Hospital, Gentofte, Copenhagen 15 participants Est. completion 2017-12-10 1 siteOther conditions: Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT03373435
Safety and Efficacy of Exendin 9-39 in Patients With Postbariatric Hypoglycemia
Not yet reported Eiger BioPharmaceuticals 18 participants Est. completion 2019-03-15 5 sitesOther conditions: Postbariatric HypoglycemiaView official trial listing → -
Completed NCT NCT03950245
Incretin Hormone Antagonism After Bariatric Surgery
Not yet reported Hvidovre University Hospital 36 participants Est. completion 2021-04-16 2 sitesOther conditions: Bariatric SurgeryView official trial listing → -
Completed NCT NCT04347252
Glucagon Regulation of Glucose Metabolism
Not yet reported David D'Alessio, M.D. 19 participants Est. completion 2021-04-16 1 siteOther conditions: Insulin SecretionView official trial listing → -
Completed NCT NCT04652479
Avexitide Safety and Efficacy to Treat Acquired Hyperinsulinemic Hypoglycemia
Not yet reported Dr. Tracey McLaughlin, MD 25 participants Est. completion 2022-06-30 1 siteOther conditions: Acquired Hyperinsulinemic HypoglycemiaView official trial listing → -
Completed NCT NCT05177653
Separate and Combined Extrapancreatic Effects of the Incretin Hormones
Not yet reported University Hospital, Gentofte, Copenhagen 13 participants Est. completion 2023-03-03 1 siteOther conditions: Pancreatectomy; HyperglycemiaView official trial listing → -
Status unknown NCT NCT06498063
The Underlying Mechanisms Regarding the Effect of Glucagon on the Kidneys Will be Investigated in Healthy Males.
Not yet reported Ali Asmar 10 participants Est. completion 2025-07-31 1 siteOther conditions: Kidney DiseasesView official trial listing → -
Active, not recruiting NCT NCT06747468
Avexitide for Treatment of Post-Bariatric Hypoglycemia
Not yet reported Amylyx Pharmaceuticals Inc. 75 participants Est. completion 2027-02 21 sitesOther conditions: Post Bariatric HypoglycemiaView official trial listing → -
Not yet recruiting NCT NCT06872060
The Effects of Glucagon on Renal Regional Blood Flow in Humans Measured by Magnetic Resonance.
Not yet reported Bispebjerg Hospital 10 participants Est. completion 2027-11-01Other conditions: Kidney DiseasesView official trial listing → -
Not yet recruiting NCT NCT06972407
The Effect of rs7903146 Genotype on Islet GLP-1 Production in Humans
Not yet reported Mayo Clinic 80 participants Est. completion 2029-03-01 1 siteOther conditions: Genetic Predisposition, Type2diabetesView official trial listing → -
Completed NCT NCT07373236
The Effect of Endogenous GLP-1 on Glucagon Secretion in Type 1 Diabetes
Not yet reported Asger Lund, MD 12 participants Est. completion 2026-04-09 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Available NCT NCT07582874
An Expanded Access Protocol to Provide Avexitide in Patients With Post-Bariatric Hypoglycemia
Amylyx Pharmaceuticals Inc. 4 sitesOther conditions: Post-bariatric HypoglycemiaView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
