About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Empagliflozin
- Company
- Boehringer Ingelheim
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 190 recruiting
Efficacy results: Not yet reported
190 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 7, 2026
Find a Clinical Trial Near Me
See recruiting studies for Empagliflozin and check eligibility with the study team.
Trial details
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Recruiting NCT NCT02378805
Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome
University Hospital Goettingen 800 participants Est. completion 2036-03-01 1 siteOther conditions: Alport Syndrome, Hereditary Kidney Disease, Pediatric Kidney Disease, Thin Basement Membrane Disease, Familial Benign HematuriaView official trial listing → -
Recruiting NCT NCT03424005
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
Not yet reported, Not yet reported Hoffmann-La Roche 1132 participants Est. completion 2030-09-30 53 sites Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT03878706
The Cardiovascular Effect of GLP-1 Agonist, SGLT2 Inhibitor and Their Combination
University of Athens 240 participants Est. completion 2027-06-30 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT04286399
Asian Diabetes Outcomes Prevention Trial
Not yet reported National Heart Centre Singapore 2400 participants Est. completion 2034-06-30 1 siteCardiovascular disease Other conditions: Diabetes MellitusView official trial listing → -
Recruiting NCT NCT04381936
Randomised Evaluation of COVID-19 Therapy
Not yet reported University of Oxford 70000 participants Est. completion 2038-09-30 16 sitesOther conditions: PneumoniaView official trial listing → -
Recruiting NCT NCT04602754
Efficacy and Safety of Berlim 25/20 Association in the Treatment of Type II Diabetes Mellitus and Dyslipidemia.
Not yet reported EMS 228 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: Dyslipidemia Associated With Type II Diabetes MellitusView official trial listing → -
Recruiting NCT NCT04662723
Multicentre Clinical Study to Evaluate the Effect of Personalized Therapy on Patients With Immunoglobulin A Nephropathy.
Not yet reported Fondazione Schena 878 participants Est. completion 2028-12-31 2 sites Stand-aloneOther conditions: Glomerulonephritis, Immunoglobulin A NephropathyView official trial listing → -
Recruiting NCT NCT04670666
Efficacy and Safety of Madalena Association in the Treatment of Type II Diabetes Mellitus
Not yet reported EMS 270 participants Est. completion 2027-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT04768322
LVAD Versus GDMT in Ambulatory Advanced Heart Failure Patients
Not yet reported Hospices Civils de Lyon 92 participants Est. completion 2029-02 8 sitesHeart failureView official trial listing → -
Recruiting NCT NCT04899479
Peri-treatment of SGLT-2 Inhibitor on Myocardial Infarct Size and Remodeling Index in Patients With Acute Myocardial Infarction and High Risk of Heart Failure Undergoing Percutaneous Coronary Intervention
Not yet reported Samsung Medical Center 200 participants Est. completion 2025-12-30 1 site Stand-aloneCardiovascular diseaseHeart failureView official trial listing → -
Recruiting NCT NCT05028140
Efficacy and Safety of Piemonte Association in the Treatment of Type II Diabetes Mellitus
Not yet reported EMS 480 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: Type II DiabetesView official trial listing → -
Recruiting NCT NCT05057806
SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan
Not yet reported The University of Texas Health Science Center at San Antonio 30 participants Est. completion 2027-03-31 1 site Stand-aloneType 2 diabetesHeart failureView official trial listing → -
Recruiting NCT NCT05138575
SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial
Not yet reported University of Pennsylvania 53 participants Est. completion 2027-05-31 1 siteHeart failureView official trial listing → -
Recruiting NCT NCT05164263
Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study
Not yet reported Getz Pharma 2000 participants Est. completion 2027-08-31 6 sites Stand-aloneOther conditions: Type II Diabetes Mellitus, Efficacy, Self, Safety IssuesView official trial listing → -
Recruiting NCT NCT05180773
Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy
Not yet reported Dennis M. McNamara, MD, MS 250 participants Est. completion 2028-12-31 64 sitesOther conditions: Peripartum Cardiomyopathy, PostpartumView official trial listing → -
Recruiting NCT NCT05305911
Sodium Glucose Co-Transporter 2 (SGLT2) and STEMI
Not yet reported Minneapolis Heart Institute Foundation 81 participants Est. completion 2028-12 1 siteOther conditions: Heart Attack, Enlarged HeartView official trial listing → -
Recruiting NCT NCT05345327
SGLT2 Inhibitors As First Line Therapy to Prevent Renal Decline in Type 2 Diabetes
Not yet reported The George Institute 994 participants Est. completion 2026-06-30 8 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT05349955
Effects and Safety of Diabetic GUideline Algorithm Implementation Performed by Primary Care Physicians in the Community
Not yet reported Shanghai Zhongshan Hospital 5600 participants Est. completion 2026-11-30 13 sites Stand-aloneType 2 diabetesChronic kidney disease Other conditions: Cardiovascular ComplicationView official trial listing → -
Recruiting NCT NCT05390892
PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
Not yet reported Brigham and Women's Hospital 6000 participants Est. completion 2029-03-01 36 sitesCardiovascular disease Other conditions: Type2DiabetesView official trial listing → -
Recruiting NCT NCT05392764
Early Treatment With a Sodium-glucose Co-transporter 2 Inhibitor in High-risk Patients With Acute Heart Failure
Not yet reported Juntendo University 444 participants Est. completion 2027-12-31 69 sites Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT05501483
Adipose Tissue Heterogeneity and Its Link to Type 2 Diabetes
Not yet reported Karolinska Institutet 60 participants Est. completion 2032-12-31 1 site MixedType 2 diabetesView official trial listing → -
Recruiting NCT NCT05521984
Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)
Not yet reported Washington University School of Medicine 20 participants Est. completion 2031-06-30 1 siteOther conditions: Pediatric Brain Tumor, Pediatric Solid TumorView official trial listing → -
Recruiting NCT NCT05610956
Evaluate the Possible Efficacy and Safety of Empagliflozin in Patient With Ulcerative Colitis
Not yet reported Tanta University 60 participants Est. completion 2026-12-01 1 site Stand-aloneOther conditions: Ulcerative ColitisView official trial listing → -
Recruiting NCT NCT05612594
Adipose Dysfunction, Imaging, Physiology, and Outcomes With Sodium Glucose Cotransporter 2 Inhibitor (SGLT2i) for Sleep Apnea: The ADIPOSA Study
Not yet reported Yale University 164 participants Est. completion 2027-09 2 sitesOther conditions: Sleep ApneaView official trial listing → -
Recruiting NCT NCT05660083
Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC)
Not yet reported The Methodist Hospital Research Institute 36 participants Est. completion 2028-12-02 3 sites Stand-aloneOther conditions: HER2-negative Breast Cancer, Metastatic Breast Cancer, Metaplastic Breast Carcinoma, TNBC - Triple-Negative Breast CancerView official trial listing → -
Recruiting NCT NCT05663515
A Pan-European Post-Authorisation Safety Study: Risk of Pancreatic Cancer Among Type 2 Diabetes Patients Who Initiated Exenatide as Compared With Those Who Initiated Other Non-Glucagon-Like Peptide 1 Receptor Agonists Based Glucose Lowering Drugs
AstraZeneca 24000 participants Est. completion 2026-10-01 8 sitesOther conditions: Pancreatic CancerView official trial listing → -
Recruiting NCT NCT05669742
Empagliflozin Addition in Modulating Metabolic Disturbances Associated With Olanzapine in Schizophrenia Patients
Not yet reported Tanta University 40 participants Est. completion 2026-12 1 siteOther conditions: Sodium-glucose Transport Protein Two Inhibitor (SGLT2),Metabolic Deficits Caused by AntipsychoticsView official trial listing → -
Recruiting NCT NCT05672836
ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement
Not yet reported Duk-Woo Park, MD 1040 participants Est. completion 2029-04 31 sitesHeart failure Other conditions: Aortic Valve StenosisView official trial listing → -
Recruiting NCT NCT05715814
meChANisms and sAfety of SGLT2 Inhibition in peRitoneal dialYsis
Not yet reported University Health Network, Toronto 20 participants Est. completion 2027-12-01 1 site Stand-aloneOther conditions: Peritoneal Dialysis Complication, End Stage Kidney Disease, Sodium-glucose Co-transporter-2 Inhibitors, Kidney Dysfunction, Residual Kidney FunctionView official trial listing → -
Recruiting NCT NCT05726032
Empagliflozin in Patients With Cirrhosis and Ascites
Not yet reported Yale University 20 participants Est. completion 2026-12-01 1 siteOther conditions: Cirrhosis, Liver FailureView official trial listing → -
Recruiting NCT NCT05770687
SGLT2 Inhibitors on Clinical Outcomes and Left Ventricular Remodeling in Type 2 Diabetic Patients with Acute Myocardial Infarction, a Prospective, Multi-center Registry Study
Kiyuk Chang 1000 participants Est. completion 2026-12-31 1 siteCardiovascular diseaseType 2 diabetesView official trial listing → -
Recruiting NCT NCT05786443
Safety and Efficacy of Empagliflozin in Hemodialysis
Not yet reported NYU Langone Health 60 participants Est. completion 2026-12-30 2 sites Stand-aloneOther conditions: End Stage Renal DiseaseView official trial listing → -
Recruiting NCT NCT05831085
Diabetes-Centered Evaluation of Revascularization Strategy of Functional and Imaging-CombiNEd State-of-the-Art Percutaneous Coronary Intervention or Coronary-Artery Bypass Grafting in Patients With Diabetes Mellitus and Multivessel Coronary Artery Disease
Not yet reported Duk-Woo Park, MD 1500 participants Est. completion 2029-12-31 39 sitesOther conditions: Coronary Artery StenosisView official trial listing → -
Recruiting NCT NCT05852704
SGLT2 Inhibitor TrEatment iN Patients Awaiting cOronary arTery bYpass Surgery to Reduce Post-opErative AF
Not yet reported Region Örebro County 800 participants Est. completion 2028-12-04 8 sitesOther conditions: Chronic Coronary Syndrome, Atrial FibrillationView official trial listing → -
Recruiting NCT NCT05879276
Effect at 3 Months of Early Empagliflozin Initiation in Cardiogenic Shock Patients on Mortality, Rehospitalization, Left Ventricular Ejection Fraction and Renal Function.
Not yet reported Central Hospital, Nancy, France 164 participants Est. completion 2027-03-16 8 sites Stand-aloneOther conditions: Cardiogenic ShockView official trial listing → -
Recruiting NCT NCT05960656
SGLTi, Hepatic Glucose Production and Ketogenesis
Not yet reported The University of Texas Health Science Center at San Antonio 30 participants Est. completion 2027-06-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT05972564
The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function
Not yet reported, Not yet reported Vanderbilt University Medical Center 74 participants Est. completion 2026-12-30 1 siteMetabolic syndrome Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT06013865
Empagliflozin Treatment in Kidney Transplant Recipients
Not yet reported VA Office of Research and Development 264 participants Est. completion 2030-03-31 5 sitesChronic kidney disease Other conditions: Kidney TransplantView official trial listing → -
Recruiting NCT NCT06024746
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
Not yet reported Colorado Prevention Center 1500 participants Est. completion 2027-11 140 sites Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT06030843
The Treatment Effects of Empagliflozin on Renal Outcomes in Cardiorenal Syndrome Type 1
Not yet reported, Not yet reported Chulalongkorn University 200 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Empagliflozin in Cardiorenal Syndrome Type 1View official trial listing → -
Recruiting NCT NCT06055452
Effects of SGLT2 Inhibitors in Pre-heart Failure Populations With Hypertension
Not yet reported China National Center for Cardiovascular Diseases 120 participants Est. completion 2026-12-31 2 sites Stand-aloneHeart failure Other conditions: HypertensionView official trial listing → -
Recruiting NCT NCT06082063
Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes
Not yet reported Steno Diabetes Center Copenhagen 2000 participants Est. completion 2029-07-01 2 sitesCardiovascular diseaseHeart failure Other conditions: Type 1 Diabetes, Kidney FailureView official trial listing → -
Recruiting NCT NCT06090591
Cardiology Research Dubrava Prospective Registry
University Hospital Dubrava 3000 participants Est. completion 2033-06 1 siteHeart failure Other conditions: Arrhythmias, Cardiac, Atrial Fibrillation, Acute Coronary SyndromeView official trial listing → -
Recruiting NCT NCT06095492
Effect of Empagliflozin vs Linagliptin on Glycemic Outcomes,Renal Outcomes & Body Composition in Renal Transplant Recipients With Diabetes Mellitus
Not yet reported Medanta, The Medicity, India 200 participants Est. completion 2025-12-01 1 site Stand-aloneOther conditions: Kidney Transplant; Complications, Diabetes MellitusView official trial listing → -
Recruiting NCT NCT06110130
Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD
Not yet reported Washington D.C. Veterans Affairs Medical Center 60 participants Est. completion 2028-12-01 1 siteChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT06128980
Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy
Not yet reported, Not yet reported Herlev and Gentofte Hospital 348 participants Est. completion 2032-01 1 siteHeart failure Other conditions: Heart Rhythm DisorderView official trial listing → -
Recruiting NCT NCT06142474
SGLT2 Inhibitors in Patients With ADHF During Ventilator Weaning
Not yet reported National Taiwan University Hospital 450 participants Est. completion 2030-10-09 1 site Stand-aloneHeart failure Other conditions: Ventilator LungView official trial listing → -
Recruiting NCT NCT06143566
Polypill for Prevention of Cardiomyopathy
Not yet reported, Not yet reported University of Texas Southwestern Medical Center 200 participants Est. completion 2027-12-01 1 site Stand-aloneType 2 diabetes Other conditions: High Blood PressureView official trial listing → -
Recruiting NCT NCT06155604
SGLT2 Inhibitor in Lupus Nephritis Patients With Chronic Kidney Disease
Not yet reported The University of Hong Kong 150 participants Est. completion 2026-12-31 1 siteChronic kidney disease Other conditions: Lupus NephritisView official trial listing → -
Recruiting NCT NCT06166654
Optimal Diuretic Therapies for Acute Heart Failure With Volume Overload
Not yet reported Johannes Grand 939 participants Est. completion 2027-12-30 5 sitesHeart failureView official trial listing → -
Recruiting NCT NCT06182839
Canagliflozin in Advanced Renal Disease With MRI Endpoints
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 92 participants Est. completion 2029-03-30 1 siteChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT06183437
The STOP-MED CTRCD Trial
Not yet reported Dinesh Thavendiranathan 335 participants Est. completion 2031-12 14 sites Stand-aloneHeart failure Other conditions: Cardiotoxicity, Cardiac Toxicity, Antineoplastics Toxicity, CancerView official trial listing → -
Recruiting NCT NCT06217302
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
Not yet reported Alessandro Doria 150 participants Est. completion 2029-05 19 sitesHeart failure Other conditions: Diabetic Nephropathies, Kidney Failure, Chronic, Diabetes Mellitus Type 1View official trial listing → -
Recruiting NCT NCT06229678
Ketones, SGLT2, HFrEF
Not yet reported The University of Texas Health Science Center at San Antonio 71 participants Est. completion 2027-03-01 1 site Stand-aloneHeart failure Other conditions: Type2diabetesView official trial listing → -
Recruiting NCT NCT06249932
Empagliflozin in Heart Failure with Reduced Ejection Fraction and End Stage Renal Disease
Not yet reported National Taiwan University Hospital 95 participants Est. completion 2030-12-31 2 sites Stand-aloneHeart failure Other conditions: End Stage Renal Disease on DialysisView official trial listing → -
Recruiting NCT NCT06249945
EMPAgliflozin in Heart Failure With PReserved Ejection Fraction and End Stage Renal Disease
Not yet reported National Taiwan University Hospital 150 participants Est. completion 2030-12-31 2 sites Stand-aloneHeart failure Other conditions: End Stage Renal Disease on DialysisView official trial listing → -
Recruiting NCT NCT06250257
Bromocriptine in Dilated Cardiomyopathy Among Women of Reproductive Age
Not yet reported Jimma University 112 participants Est. completion 2026-11-30 1 siteOther conditions: Dilated CardiomyopathyView official trial listing → -
Recruiting NCT NCT06271200
Strategic Lifestyle Intervention for Metabolic Syndrome (SLIM-MET)
Not yet reported National Health Research Institutes, Taiwan 200 participants Est. completion 2027-12-31 1 siteMetabolic syndromeView official trial listing → -
Recruiting NCT NCT06283420
Metabolic Response to the Initiation of Heart Failure Therapy
Vojtech Melenovsky, MD, PhD 120 participants Est. completion 2026-12-20 1 siteHeart failureView official trial listing → -
Recruiting NCT NCT06285760
Effect of Acetazolamide on Diuresis and Natriuresis in Patients With Acute Heart Failure (SANDI STUDY)
Puerta de Hierro University Hospital 64 participants Est. completion 2026-12-31 1 siteHeart failure Other conditions: Persistent CongestionView official trial listing → -
Recruiting NCT NCT06291155
Mechanism of SGLT2 Inhibition in the Kidney
Not yet reported University of Michigan 20 participants Est. completion 2028-02-28 1 siteType 2 diabetesChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT06355310
Mechanisms of SGLT2 Inhibition in Pediatric Steatotic Liver Disease
Not yet reported Justin Ryder 40 participants Est. completion 2028-02-01 1 site Stand-aloneOther conditions: Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Recruiting NCT NCT06364930
SGLT2i to Prevent of Liver Complications in Patients With CHB and Diabetes Mellitus
Not yet reported Chinese University of Hong Kong 412 participants Est. completion 2031-03-30 1 siteOther conditions: Chronic Hepatitis BView official trial listing → -
Recruiting NCT NCT06410352
Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome
Not yet reported University Medical Center, Kazakhstan 220 participants Est. completion 2026-07-31 1 siteMetabolic syndromeView official trial listing → -
Recruiting NCT NCT06424288
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
Not yet reported Boehringer Ingelheim 6712 participants Est. completion 2028-05-22 664 sites Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT06430684
Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease
Not yet reported Ann & Robert H Lurie Children's Hospital of Chicago 40 participants Est. completion 2026-11-01 1 site Stand-aloneChronic kidney disease Other conditions: Pediatric Kidney DiseaseView official trial listing → -
Recruiting NCT NCT06435156
Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes
Not yet reported University of Dundee 320 participants Est. completion 2027-10-31 17 sitesHeart failure Other conditions: Type 1 DiabetesView official trial listing → -
Recruiting NCT NCT06446531
Prevention of Progression of Prediabetes, Obesity and CV Risk
Not yet reported The University of Texas Health Science Center at San Antonio 64 participants Est. completion 2027-07 1 site Stand-alonePrediabetesCardiovascular disease Other conditions: Weight, BodyView official trial listing → -
Recruiting NCT NCT06473844
Efficacy of SGLT2 Inhibitors in Adults With Sepsis
Not yet reported Hospital Authority, Hong Kong 60 participants Est. completion 2027-02-28 3 sites Stand-aloneOther conditions: Sepsis, Inflammation, SGLT2 Inhibitors, Critically Ill, Organ Dysfunction SyndromeView official trial listing → -
Recruiting NCT NCT06483074
Empagliflozin on Residual Kidney Function in Incident Peritoneal Dialysis Patients
Not yet reported Chinese University of Hong Kong 48 participants Est. completion 2026-10-31 1 siteOther conditions: End Stage Renal Disease on Dialysis, Peritoneal Dialysis Complication, Sodium-glucose Cotransporter-2 Inhibitor, Residual Kidney FunctionView official trial listing → -
Recruiting NCT NCT06506422
Empagliflozin Reversal of Arterial StiffnEss in Aging
Not yet reported, Not yet reported University of Missouri-Columbia 80 participants Est. completion 2029-02-28 1 site Stand-aloneOther conditions: Aging, Arterial StiffnessView official trial listing → -
Recruiting NCT NCT06507657
Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure
Not yet reported University of Minnesota 80 participants Est. completion 2029-01-15 1 site Stand-aloneCardiovascular disease Other conditions: HypertensionView official trial listing → -
Recruiting NCT NCT06520891
"The Effect of The Combination Therapy of Statin and SGLT2i in The Treatment of Ischemic Heart Disease"
Fayoum University 90 participants Est. completion 2025-12-30 1 siteOther conditions: 2 Drugs Are Statin and SGLT2iView official trial listing → -
Recruiting NCT NCT06526195
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Not yet reported Abbott Medical Devices 850 participants Est. completion 2032-09 68 sitesHeart failureCardiovascular disease Other conditions: Heart Diseases, Pulmonary HypertensionView official trial listing → -
Recruiting NCT NCT06528405
The Efficacy and Safety of Sodium-glucose Cotransporter 2 Inhibitors in Patients With Acute Kidney Disease
Not yet reported National Taiwan University Hospital 264 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Acute Kidney InjuryView official trial listing → -
Recruiting NCT NCT06554301
A Study on the Efficacy and Safety of Empagliflozin in the Treatment of Pulmonary Arterial Hypertension
Not yet reported China National Center for Cardiovascular Diseases 72 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Pulmonary Arterial HypertensionView official trial listing → -
Recruiting NCT NCT06562582
STunning in Acute Myocardial Infarction - BAS
Not yet reported Vastra Gotaland Region 120 participants Est. completion 2027-12-31 1 siteOther conditions: Myocardial InfarctView official trial listing → -
Recruiting NCT NCT06570473
Feasibility Trial for a Right Ventricular Failure Platform Trial
Not yet reported University of Alberta 30 participants Est. completion 2026-12 5 sites Stand-aloneHeart failure Other conditions: Pulmonary Hypertension, Right Ventricular DysfunctionView official trial listing → -
Recruiting NCT NCT06572215
DYNAMic Renal Assessment: NOvel Methods to Assess KIDNEY Functional Reserve
King's College Hospital NHS Trust 44 participants Est. completion 2027-12-31 1 siteChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT06593314
Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes
Not yet reported University of Texas Southwestern Medical Center 800 participants Est. completion 2026-10-15 1 siteHeart failure Other conditions: DiabetesView official trial listing → -
Recruiting NCT NCT06600178
Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)
Not yet reported University of Virginia 150 participants Est. completion 2029-06-29 1 siteCardiovascular disease Other conditions: Coronary Microvascular Disease, Coronary Microvascular Dysfunction (CMD)View official trial listing → -
Recruiting NCT NCT06609356
Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes
Not yet reported Vanderbilt University Medical Center 27 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Type 1 Diabetes Mellitus, Glucokinase-Maturity Onset Diabetes of the Young (GCK-MODY), MODY2 Diabetes, Healthy VolunteerView official trial listing → -
Recruiting NCT NCT06613854
Effect of Early Combination Antihyperglycemic Treatment on Metabolic Control in Individuals With Type 2 Diabetes
Not yet reported University Medical Centre Ljubljana 90 participants Est. completion 2027-12 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06625073
Randomized Trial of SGLT2i in Heart Transplant Recipients
Not yet reported VA Office of Research and Development 200 participants Est. completion 2030-02-28 6 sites Stand-aloneCardiovascular disease Other conditions: Heart Transplant, Kidney DiseaseView official trial listing → -
Recruiting NCT NCT06627322
A Registry-based Randomized Controlled Trial in Type 2 Diabetes With Cardiovascular Risk Factors (REMATCH)
Not yet reported Kyu Chang Won 5950 participants Est. completion 2029-09-30 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT06642272
A Pragmatic Trial Comparing Empagliflozin and Dapagliflozin Through Cluster Randomization Embedded in the Electronic Health Record
Not yet reported Herlev and Gentofte Hospital 17200 participants Est. completion 2028-12-31 12 sitesType 2 diabetesHeart failureChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT06642623
A Prospective Trial of Enavogliflozin to Evaluate Cardio-renal Outcome in Type 2 Diabetes Mellitus Patients
Not yet reported Yonsei University 2862 participants Est. completion 2030-12-31 1 siteType 2 diabetesCardiovascular disease Other conditions: Kidney DiseasesView official trial listing → -
Recruiting NCT NCT06653738
Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention
Not yet reported Insel Gruppe AG, University Hospital Bern 400 participants Est. completion 2030-09 21 sites Stand-aloneOther conditions: Kidney Stone, Nephrolithiasis, Dietary ExposureView official trial listing → -
Recruiting NCT NCT06655480
Triple Combination Therapy (ARNI, SGLT2i, MRA) in Advanced HFpEF
Not yet reported National Medical Research Center for Cardiology, Ministry of Health of Russian Federation 50 participants Est. completion 2027-12-31 1 site Stand-aloneHeart failure Other conditions: LVDD, Myocardial FibrosisView official trial listing → -
Recruiting NCT NCT06668389
Sodium-Glucose Cotransporter 2 Inhibitors for Repaired Tetralogy of Fallot Patients for Enhancement of Cardio-Pulmonary Status Trial
Not yet reported The University of Hong Kong 106 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Congenital Heart Disease, Repaired Tetralogy of Fallot (rTOF), Pulmonary Regurgitation, Sodium-glucose Cotransporter 2 (SGLT2) Inhibitor, Dapagliflozin (Forxiga)View official trial listing → -
Recruiting NCT NCT06674109
SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial
Not yet reported Massachusetts General Hospital 60 participants Est. completion 2028-02-28 1 site Stand-aloneOther conditions: Gout and HyperuricemiaView official trial listing → -
Recruiting NCT NCT06676384
Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can Significantly Improve the Slope of Estimated Glomerular Filtration Rate at Two Years When Compared to Standard of Care Alone in South-Asian Kidney Biopsy-proven Adult (≥18 Years) Primary IgA Nephropathy?
Not yet reported Christian Medical College, Vellore, India 585 participants Est. completion 2029-08 12 sitesOther conditions: IgA Nephropathy, Renal Insufficiency, Chronic, IgA Vasculitis, IGA GlomerulonephritisView official trial listing → -
Recruiting NCT NCT06706791
Effect of Empagliflozin on Quality of Life in Chronic Heart Failure Patients With Diabetes Mellitus Type II
Not yet reported Fazaia Ruth Pfau Medical College 156 participants Est. completion 2026-12-01 1 site Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT06715449
EMPA-ESUS. a Randomised Control Trial to Investigate the Impact of Empagliflozin on Left Atrial Function in Patients with Embolic Stroke of Undetermined Source
Not yet reported, Not yet reported University of East Anglia 100 participants Est. completion 2029-03 1 site Stand-aloneCardiovascular disease Other conditions: Atrial Fibrillation New OnsetView official trial listing → -
Recruiting NCT NCT06727409
Use of Clinical-trials and Simulation Models to Estimate Cost-effectiveness of Non-steroidal Mineralocorticoid Antagonists, RASi and SGLT2i as Triple Therapy With Type 2 Diabetes and Chronic Kidney Disease
Not yet reported Chinese University of Hong Kong 82 participants Est. completion 2026-12-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT06729996
Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis/Acute Pancreatitis Associated Diabetes Mellitus
Not yet reported Mayo Clinic 50 participants Est. completion 2027-05-31 3 sites Stand-aloneOther conditions: Pancreatitis, Chronic, Pancreatitis, Acute, Diabetes MellitusView official trial listing → -
Recruiting NCT NCT06745063
Arterial Destiffening Effects of SGLT2 Inhibition in Veterans With Obesity
Not yet reported VA Office of Research and Development 50 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Obesity, Vascular HealthView official trial listing → -
Recruiting NCT NCT06750172
Simplification of Oral Sodium Loading Test in the Diagnosis of Primary Aldosteronism: 2-day Replacing 3-day Method
Peking Union Medical College Hospital 33 participants Est. completion 2024-12-25 1 siteOther conditions: Primary AldosteronismView official trial listing → -
Recruiting NCT NCT06762964
CAMEO-FONTAN -Dapagliflozin in the Failing Fontan Circulation
Not yet reported Mayo Clinic 27 participants Est. completion 2027-02 1 siteHeart failure Other conditions: Fontan Circulation, Single Ventricle Heart DiseaseView official trial listing → -
Recruiting NCT NCT06783166
Assessing the Clinical Outcomes of Dapagliflozin Versus Acetazolamide in Patients With Acute Heart Failure
Not yet reported, Not yet reported Mansoura University 100 participants Est. completion 2025-08-01 1 siteHeart failureView official trial listing → -
Recruiting NCT NCT06821919
Impact of Antiglycemic & Immunosuppressive Therapies on NETosis in Diabetes & Kidney Disease (NETs - Neutrophil Traps)
Western Galilee Hospital-Nahariya 70 participants Est. completion 2031-12-30 1 siteOther conditions: Diabetes Mellitus, Kidney DiseaseView official trial listing → -
Recruiting NCT NCT06838286
Korean Study on Safety and Effectiveness of OAD Triple Therapy in Type 2 Diabetes
Chong Kun Dang Pharmaceutical 10000 participants Est. completion 2029-12-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06843902
Improving Coronary Vascular Health in Women
Not yet reported Massachusetts General Hospital 80 participants Est. completion 2029-06 1 site Stand-aloneOther conditions: HIV-1-infection, Coronary Microvascular Dysfunction, Metabolic DiseaseView official trial listing → -
Recruiting NCT NCT06845163
Randomized Clinical Trial to Evaluate the Effect of Dapagliflozin in Patients With Diabetic Macular Edema
Not yet reported Alexandria University 56 participants Est. completion 2026-08 1 siteOther conditions: Diabetic Macular Edema, Center-involved Diabetic Macular EdemaView official trial listing → -
Recruiting NCT NCT06846411
The EMPA-FIT Study
Not yet reported Seoul National University Bundang Hospital 46 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Diabetes, Diabetes Mellitus, Type IIView official trial listing → -
Recruiting NCT NCT06862739
Glycemic Control With Triple Pathway Approach Through Empagliflozin, Linagliptin and Metformin Combination
Not yet reported Nabiqasim Industries (Pvt) Ltd 800 participants Est. completion 2026-06-30 2 sitesOther conditions: Diabetes Mellitus, Type 2 DMView official trial listing → -
Recruiting NCT NCT06863532
Efficacy and Safety Comparison of Cofrogliptin Add-on Versus Metformin Dose-escalation in Type 2 Diabetes Patients Inadequately Controlled With SGLT-2 Inhibitors Plus Low-Dose Metformin:A Multicenter, Open-Label Trial
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 80 participants Est. completion 2026-09-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT06887062
Dapagliflozin and Endothelin Receptor Antagonism in Large Vessel Vasculitis (DERAIL-LVV)
Not yet reported University of Edinburgh 60 participants Est. completion 2027-07-01 1 siteOther conditions: Large Vessel Vasculitis, Giant Cell Arteritis (GCA), Takayasu ArteritisView official trial listing → -
Recruiting NCT NCT06894784
A Clinical Trial to Evaluate The Effects of Semaglutide and Empagliflozin Combined to Automated Insulin Delivery on Diabetes Control in Adults Living With Type 1 Diabetes
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 36 participants Est. completion 2027-01 1 site Added to GLP-1Other conditions: Diabetes Type 1View official trial listing → -
Recruiting NCT NCT06905405
The Use of Advanced Imaging in HFpEF
Sheffield Teaching Hospitals NHS Foundation Trust 40 participants Est. completion 2027-09-30 2 sitesHeart failureView official trial listing → -
Recruiting NCT NCT06913647
Effect of Canagliflozin on Ultrafiltration & Fibrosis in Patients on Peritoneal Dialysis
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 30 participants Est. completion 2028-12-31 1 siteChronic kidney disease Other conditions: ESRDView official trial listing → -
Recruiting NCT NCT06929169
Cardiovascular Effects of SGLT2 Inhibitors in Hemodialysis Patients: A Phase 2 Randomized Study
Not yet reported Maximo Agustin Schiavone 80 participants Est. completion 2026-08 1 site Stand-aloneChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT06930092
RestoratIon of Myocardial Function by PeRcutaneous cOronary interVEntion in Patients With Ischemic CardioMyoPathy
Not yet reported Seoul National University Hospital 158 participants Est. completion 2029-04-30 1 siteOther conditions: Ischemic CardiomyopathyView official trial listing → -
Recruiting NCT NCT06932081
Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry
Leiden University Medical Center 400 participants Est. completion 2027-12-31 11 sitesOther conditions: Adult Congenital Heart Disease, Congenital Heart Disease, Systemic Right Ventricle, Transposition of the Great Arteries, Congenitally Corrected Transposition of the Great Arteries, Fontan, Single Ventricle, Tetralogy of Fallot (TOF)View official trial listing → -
Recruiting NCT NCT06935370
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
Not yet reported Boehringer Ingelheim 4200 participants Est. completion 2029-02-22 585 sites Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT06955260
SGLT2 Inhibition With Empagliflozin in Fontan Circulatory Failure
Not yet reported Subodh Verma 410 participants Est. completion 2028-03 2 sitesOther conditions: Congenital Heart DiseaseView official trial listing → -
Recruiting NCT NCT06972732
A Phase IV Clinical Trial to Compare the Efficacy and Safety of Metformin+Sodium-Glucose Cotransporter 2 Inhibitor(SGLT2-i)+Thiazolidinedione (TZD) in Patients With Type 2 Diabetes
Not yet reported Boryung Pharmaceutical Co., Ltd 204 participants Est. completion 2026-10-01 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT06983054
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes
Not yet reported Amsterdam UMC, location VUmc 34 participants Est. completion 2025-12 2 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT06989723
Pioglitazone and Empagliflozin for Fatty Liver Disease in Type 2 Diabetes
Not yet reported Seoul National University Bundang Hospital 120 participants Est. completion 2027-06-30 1 site Stand-aloneType 2 diabetes Other conditions: Fatty LiverView official trial listing → -
Recruiting NCT NCT06992440
Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial Hypertension
Not yet reported Gustavo A Heresi, MD, MS 78 participants Est. completion 2030-09 3 sitesOther conditions: Pulmonary Arterial HypertensionView official trial listing → -
Recruiting NCT NCT07018622
Protecting the Kidney's Proximal Tubules From Platinum-Based Chemotherapy Toxicity
Not yet reported Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 46 participants Est. completion 2026-10-30 1 siteOther conditions: Solid Tumors, Cisplatin NephrotoxicityView official trial listing → -
Recruiting NCT NCT07019012
Cofrogliptin Once Every 2 Weeks as Add-on Therapy to Metformin and Dapagliflozin Versus Daily Linagliptin in Patients With Type 2 Diabetes.
Not yet reported Huazhong University of Science and Technology 170 participants Est. completion 2026-12-30 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07023172
Multicenter, Prospective, Observational Study on the Treatment of Type 2 Diabetes With Proline Plus Empagliflozin Tablets
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 3000 participants Est. completion 2027-10 2 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT07025629
Dapagliflozin for Cardio-renal Protection After ICU Discharge
Not yet reported Assistance Publique - Hôpitaux de Paris 600 participants Est. completion 2029-01-15 2 sitesHeart failureChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT07038356
Effects of Continued Administration of Empagliflozin in Patients With Heart Failure on Active SGLT2 Inhibitor Treatment Admitted for Acute Decompensated Heart Failure
Not yet reported Christian Schulze 536 participants Est. completion 2027-06-30 12 sitesHeart failureView official trial listing → -
Recruiting NCT NCT07053293
SGLT2i, Hepatic Glucose Production, and SNS
Not yet reported The University of Texas Health Science Center at San Antonio 22 participants Est. completion 2027-06-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07053306
SGLT2i, Ketoacidosis, Volume Contraction, and Insulinopenia
Not yet reported The University of Texas Health Science Center at San Antonio 29 participants Est. completion 2027-06-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07053319
SGLT2i, Pioglitazone, and Ketone Production in T2D
Not yet reported The University of Texas Health Science Center at San Antonio 64 participants Est. completion 2027-06-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07055282
SGLT2i in Kidney Stones
Not yet reported University of Chicago 32 participants Est. completion 2028-11-01 1 siteOther conditions: Kidney StonesView official trial listing → -
Recruiting NCT NCT07056699
SGLT2i, Pioglitazone, and Ketone Production in T1D
Not yet reported The University of Texas Health Science Center at San Antonio 24 participants Est. completion 2027-06-30 1 siteOther conditions: Type1diabetesView official trial listing → -
Recruiting NCT NCT07064473
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Not yet reported Boehringer Ingelheim 11800 participants Est. completion 2029-12-21 1142 sites Stand-aloneType 2 diabetesCardiovascular disease Other conditions: HypertensionView official trial listing → -
Recruiting NCT NCT07070765
Sodium-glucose Transporter Type 2 Inhibition in Anthracycline-related Cardiotoxicity
Not yet reported University of Aberdeen 70 participants Est. completion 2028-10-31 2 sitesOther conditions: Breast CancerView official trial listing → -
Recruiting NCT NCT07074418
Effect of Empagliflozin in Patients With eGFR Between 10 and 20 ml/Min/1.73m2
Not yet reported Centre Hospitalier Universitaire de Nice 34 participants Est. completion 2028-05 1 siteChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT07076823
Safety and Efficacy of Canagliflozin in Patients With Metastatic High Microsatellite Instability (MSI-H) Colorectal Cancer
Not yet reported West China Hospital 15 participants Est. completion 2026-06-30 1 siteOther conditions: Colorectal Cancer, SGLT-2 InhibitorView official trial listing → -
Recruiting NCT NCT07093476
Efficacy and Safety of Add-On Therapy With Empagliflozin in Patients With Type 2 Diabetes on a Background of Alogliptin and Metformin
Not yet reported Celltrion 171 participants Est. completion 2027-04 1 siteType 2 diabetes Other conditions: Diabete Type 2, DMView official trial listing → -
Recruiting NCT NCT07107945
A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)
Not yet reported Boehringer Ingelheim 120 participants Est. completion 2028-04-14 93 sites Stand-aloneChronic kidney diseaseView official trial listing → -
Recruiting NCT NCT07110415
Efficacy and Safety Trials of Yangxinshi Tablets in the Treatment of Patients With Coronary Heart Disease Complicated by Cardiac Dysfunction
Not yet reported SPH Qingdao Growful Pharmacetical Co.,Ltd 2708 participants Est. completion 2030-12-31 96 sites Stand-aloneOther conditions: Coronary Heart Disease, Cardiac DysfunctionView official trial listing → -
Recruiting NCT NCT07119424
Multidisciplinary Dissection of Renal and Metabolic Effects of Glyfozines on Elderly Patients: From Molecular Aspects to Clinical Indications
Chiara Lanzani 300 participants Est. completion 2027-02 1 siteOther conditions: Elderly Patients (>65 Years), Diabetes (DM), Heart Disease, Renal Diseases, Internal DiseaseView official trial listing → -
Recruiting NCT NCT07141355
Empagliflozin's Microcirculatory Effects in Cardiogenic Shock: an Ancillary Pilot Study of the EMPASHOCK Trial
Not yet reported University Hospital, Strasbourg, France 24 participants Est. completion 2027-09-30 1 siteOther conditions: Cardiogenic ShockView official trial listing → -
Recruiting NCT NCT07143773
SGLT2i Safety and Efficacy on Kidney Allograft Function in Non-diabetic Kidney Transplant Recipients
Not yet reported Odense University Hospital 88 participants Est. completion 2027-08-01 1 siteOther conditions: Kidney Transplantation Recipients, Sodium-Glucose Transporter 2 Inhibitors, Non-Diabetic Patients, Randomized Controlled Trial, Placebo Control DesignView official trial listing → -
Recruiting NCT NCT07157475
Vascular Complications in Patients Undergoing Peripheral Revascularization and Taking SGLT-2 Inhibitors
Wroclaw Medical University 300 participants Est. completion 2026-12-31 1 siteOther conditions: Peripheral Arterial Disease(PAD)View official trial listing → -
Recruiting NCT NCT07169422
Improving Kidney Care in Type 2 Diabetes: A Study of Pharmacist Prescribing Versus Usual Care
Not yet reported Nova Scotia Health Authority 120 participants Est. completion 2028-07-01 1 siteChronic kidney diseaseType 2 diabetesView official trial listing → -
Recruiting NCT NCT07172971
Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy
Not yet reported Vanderbilt University Medical Center 10 participants Est. completion 2028-02-01 1 site Stand-aloneOther conditions: Duchenne Muscular Dystrophy (DMD)View official trial listing → -
Recruiting NCT NCT07174687
SGLT2 Inhibitors in Geographic Atrophy
Not yet reported Washington University School of Medicine 70 participants Est. completion 2028-06 1 site Stand-aloneOther conditions: Retinal Degeneration, Retinal Diseases, Eye Diseases, Geographic Atrophy, Pathological Conditions, AnatomicalView official trial listing → -
Recruiting NCT NCT07175051
Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin
Not yet reported University of Illinois at Chicago 20 participants Est. completion 2030-10 1 site Stand-aloneOther conditions: Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0), AlbuminuriaView official trial listing → -
Recruiting NCT NCT07214818
SGLT2 Inhibitors in Adult Primary Nephrotic Syndrome
Not yet reported, Not yet reported Mansoura University 75 participants Est. completion 2026-09-06 1 site Stand-aloneOther conditions: Nephrotic SyndromeView official trial listing → -
Recruiting NCT NCT07228195
SGLT2i Therapy in Islet Transplantation (SIT)
Not yet reported University of Minnesota 40 participants Est. completion 2028-12-01 1 siteOther conditions: Partial Islet Function, TPIAT, DiabetesView official trial listing → -
Recruiting NCT NCT07231939
Use of Flozins (Empagliflozin/Dapagliflozin) for Prevention of AKI
Collegium Medicum w Bydgoszczy 4000 participants Est. completion 2026-03-31 1 siteCardiovascular disease Other conditions: Acute Kidney Injury, Contrast-Induced Acute Kidney Injury, Percutaneous Coronary InterventionView official trial listing → -
Recruiting NCT NCT07239011
Dapagliflozin in Depression
Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2026-12-20 1 siteOther conditions: DepressionView official trial listing → -
Recruiting NCT NCT07240844
Enavogliflozin for the Management of Patients With Amyloid CardiomyopaThy
Not yet reported Seoul St. Mary's Hospital 68 participants Est. completion 2027-05-31 2 sitesOther conditions: Amyloid CardiomyopathyView official trial listing → -
Recruiting NCT NCT07244003
Efficacy and Safety of the Met+SGLT-2i+GLP-1RA in Patients With Type 2 Diabetes With Poor Glycemic Control
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 430 participants Est. completion 2028-06-30 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07245069
Use of Dapagliflozin in Primary Prevention of Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients
Not yet reported University Medical Centre Ljubljana 100 participants Est. completion 2029-02 1 siteHeart failure Other conditions: Anthracycline-induced Cardiac Toxicity, Endothelial Function (FMD), Arterial Stiffness, Breast CancerView official trial listing → -
Recruiting NCT NCT07273838
Sodium-Glucose Cotransporter-2 Inhibitor for Patients With Acute Cardiorenal Syndrome
Not yet reported Yale University 130 participants Est. completion 2029-10-31 2 sites Stand-aloneHeart failure Other conditions: Acute Kidney InjuryView official trial listing → -
Recruiting NCT NCT07280585
STOP-PKD: SGLT2-inhibition to Improve Prognosis in Polycystic Kidney Disease
Not yet reported University of Cologne 420 participants Est. completion 2030-05-15 30 sitesOther conditions: Polycystic Kidney, Autosomal DominantView official trial listing → -
Recruiting NCT NCT07292909
Effect of Empagliflozin on Inflammation
Not yet reported Hotel Dieu de France Hospital 100 participants Est. completion 2027-09-30 1 siteCardiovascular disease Other conditions: Inflamation, PCI, SGLT 2 InhibitorsView official trial listing → -
Recruiting NCT NCT07304817
Comparative Study on the Mode of Action of Vicadrostat and Spironolactone on Protein Profiles and Renal Hemodynamic Effects (COMPARE-VS)
Not yet reported University Medical Center Groningen 100 participants Est. completion 2028-02 2 sites Stand-aloneChronic kidney diseaseCardiovascular diseaseHeart failureView official trial listing → -
Recruiting NCT NCT07309094
Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD
Cardenal Herrera University 250 participants Est. completion 2028-12-31 1 siteChronic kidney diseaseType 2 diabetes Other conditions: ObesityView official trial listing → -
Recruiting NCT NCT07314684
GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM
Not yet reported Federico II University 80 participants Est. completion 2027-03-08 2 sitesType 2 diabetesView official trial listing → -
Recruiting NCT NCT07322237
DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With Cirrhosis
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 400 participants Est. completion 2029-06-30 1 siteOther conditions: Cirrhotic Cardiomyopathy, Empagliflozin, Cardiometabolic Risk Factors, CirrhosisView official trial listing → -
Recruiting NCT NCT07323524
Dapagliflozin in Active Lupus Nephritis
Not yet reported Brigham and Women's Hospital 33 participants Est. completion 2030-01 2 sitesOther conditions: Lupus Nephritis (LN)View official trial listing → -
Recruiting NCT NCT07331389
A Drug-Drug Interaction Study of HDM1002 and Metformin, Empagliflozin, Midazolam, Valsartan, and Warfarin
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 111 participants Est. completion 2026-06-13 1 site Stand-aloneOther conditions: Overweight Subject, Healthy SubjectsView official trial listing → -
Recruiting NCT NCT07335900
A Clinical Study Using FAPI-PET Imaging to Assess the Postoperative Effects of TAVI in Patients With Aortic Stenosis
Not yet reported RenJi Hospital 25 participants Est. completion 2027-05-30 1 site Stand-aloneOther conditions: Severe Aortic Valve StenosisView official trial listing → -
Recruiting NCT NCT07336797
Effect of Empagliflozin on Metabolic Outcomes in Adults Living With HIV Receiving Dolutegravir-Based Therapy
Not yet reported Abdelrahman Mahmoud 66 participants Est. completion 2027-12-30 1 site Stand-aloneMetabolic syndrome Other conditions: Obesity & Overweight, HIV (Human Immunodeficiency Virus)View official trial listing → -
Recruiting NCT NCT07355023
AI-Enabled Electrocardiogram-Guided Guideline-Directed Medical Therapy on Incident Left Ventricular Dysfunction: A Target Trial Emulation Study
Not yet reported Tri-Service General Hospital (TSGH) 5000 participants Est. completion 2026-01-15 1 siteOther conditions: Left Ventricular (LV) Systolic DysfunctionView official trial listing → -
Recruiting NCT NCT07372040
Add-on Diuretics in Acute Decompensated Heart Failure
Not yet reported Tanta University 66 participants Est. completion 2027-02-01 1 siteHeart failureView official trial listing → -
Recruiting NCT NCT07374328
Triple Hypoglycemic Regimens In Patients With Newly Diagnosed Type 2 Diabetes Mellitus
Not yet reported, Not yet reported Second Affiliated Hospital of Guangzhou Medical University 240 participants Est. completion 2026-08-31 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07405944
Vericiguat and Reverse Remodeling Indices in Heart Failure
Not yet reported University Medical Centre Ljubljana 70 participants Est. completion 2027-12-31 4 sites Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT07434791
Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD)
Not yet reported Sunnybrook Health Sciences Centre 100 participants Est. completion 2029-09 1 site Stand-aloneChronic kidney diseaseType 2 diabetesView official trial listing → -
Recruiting NCT NCT07442006
Glycemic Variability of Combination Therapies in T2DM
Not yet reported JW Pharmaceutical 178 participants Est. completion 2027-03-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Recruiting NCT NCT07444203
Transformative Research in Diabetic Nephropathy 2.0
University of Pennsylvania 200 participants Est. completion 2028-11-12 1 siteType 2 diabetes Other conditions: Diabetic Nephropathies, Kidney Diseases, Renal Insufficiency, ChronicView official trial listing → -
Recruiting NCT NCT07469943
The Effect of Sodium Glucose Co-trnasportert Type 2 Inhibitors on Arterial Stiffness, Endothelial Glycocalyx Thickness and Cardiac Deformation After Acute Myocardial Infarction
University of Athens 80 participants Est. completion 2028-12-20 1 siteCardiovascular disease Other conditions: Diabete Type 2View official trial listing → -
Recruiting NCT NCT07482020
SGLT2i Improve Left Atrial Function in Patients With Paroxysmal Atrial Fibrillation, Hypertension and Abnormal Glucose Metabolism
Not yet reported Huashan Hospital 66 participants Est. completion 2027-06-30 1 siteOther conditions: Atrial Fibrillation (AF), HypertensionView official trial listing → -
Recruiting NCT NCT07482943
The Effect of Dapagliflozin on Exercise and Cardiac Functional Status of Patients After Fontan Procedure
Not yet reported The University of Hong Kong 30 participants Est. completion 2028-07 2 sitesHeart failureCardiovascular disease Other conditions: Fontan, Dapagliflozin, Sodium-GLucose coTransporter-2 InhibitorsView official trial listing → -
Recruiting NCT NCT07491042
Impact of SGLT2 Inhibitors on Chronic Peritoneal Dialysis Patients.
Not yet reported Oman Ministry of Health 38 participants Est. completion 2027-01-31 1 site Stand-aloneOther conditions: End Stage Chronic Renal FailureView official trial listing → -
Recruiting NCT NCT07513883
The Assessment of Partial Guideline-Directed Medical Therapy Down Titration in Heart Failure in Remission.
Not yet reported Ziekenhuis Oost-Limburg 100 participants Est. completion 2028-12 1 site Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT07560982
Evaluating Adherence to Guideline-Directed Medical Therapy in Patients With Advanced Heart Failure
Università Vita-Salute San Raffaele 300 participants Est. completion 2036-07-01 2 sitesHeart failureView official trial listing → -
Recruiting NCT NCT07569640
HFrEF Polypill in Sri Lanka RCT
Not yet reported Washington University School of Medicine 1672 participants Est. completion 2029-04 11 sites Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT07572032
Delayed Initiation of ARNI and SGLT2i in Heart Failure With Corrected Aetiology (DELAY-HF), Pilot Study
Not yet reported Kyungsub Song 80 participants Est. completion 2028-12-20 4 sites Stand-aloneCardiovascular diseaseHeart failure Other conditions: Valvular CardiomyopathyView official trial listing → -
Recruiting NCT NCT07601867
Effect of Dapagliflozin on Right Ventricular-Pulmonary Artery Coupling After Off-Pump Coronary Atery Bypass Grafting
Pyatigorsk City Clinical Hospital Number 1 72 participants Est. completion 2028-07-01 1 siteHeart failure Other conditions: Coronary Arterial DiseaseView official trial listing → -
Recruiting NCT NCT07614230
SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue in Diabetes
Not yet reported Junjie Yang 144 participants Est. completion 2028-12-31 2 sites Stand-aloneType 2 diabetesCardiovascular disease Other conditions: AtherosclerosisView official trial listing → -
Recruiting NCT NCT07631156
STEPwise De-escalation and Optimizing Withdrawal of ARNI and SGLT2i in Normalized Heart Failure
Not yet reported Kyungsub Song 80 participants Est. completion 2029-12-30 5 sites Stand-aloneHeart failure Other conditions: Ventricular Dysfunction, LeftView official trial listing → -
Recruiting NCT NCT07653477
Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Metformin ± Sulfonylurea/SGLT2 Inhibitor Therapy (UNIGUIDE-2)
Not yet reported The United Bio-Technology (Hengqin) Co., Ltd. 956 participants Est. completion 2028-02-29 1 siteType 2 diabetesView official trial listing → -
Recruiting NCT NCT07684326
"Exploring the Potential Benefits of Using Dapagliflozin in Cirrhotic Chronic Liver Disease Patients- A Randomized Controlled Trial"
Not yet reported, Not yet reported Beni-Suef University 52 participants Est. completion 2027-09 1 siteOther conditions: Ascites HepaticView official trial listing → -
Recruiting NCT NCT07692256
the Clinical Outcome of Empagliflozin in Pediatric Heart Failure Patients
Not yet reported Ain Shams University 60 participants Est. completion 2027-02-01 1 site Stand-aloneHeart failureView official trial listing → -
Recruiting NCT NCT07700940
The Efficacy of Empagliflozin on Kidney Functions in Lupus Nephritis Population
Not yet reported Ahmed Yehia Ismail 66 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: Lupus Nephritis (LN)View official trial listing → -
Recruiting NCT NCT07703163
Safety and Efficacy of Canagliflozin in Patients With Locally Advanced or Advanced Solid Cancer
Not yet reported West China Hospital 15 participants Est. completion 2028-07-31 1 siteOther conditions: Solid Tumor, SGLT 2 InhibitorsView official trial listing → -
Recruiting NCT NCT07709208
Mitral Valve Edge-to-Edge Repair in Patients With Exercise-Induced Severe Mitral Regurgitation
Not yet reported Jena University Hospital 246 participants Est. completion 2030-06 2 sitesHeart failure Other conditions: Mitral Regurgitation FunctionalView official trial listing → -
Recruiting NCT NCT07771010
The Effect of Empagliflozin and Metformin on Oxidative Capacity and Microvascular Reactivity of Skeletal Muscle in Patients With Type 2 Diabetes Mellitus
Not yet reported University Medical Centre Ljubljana 54 participants Est. completion 2028-07-31 1 siteOther conditions: Diabetes Type 2View official trial listing → -
Recruiting NCT NCT07773272
Cardiovascular-kidney-metabolic (CKM)-Guided Therapy for Patients After Acute Coronary Syndrome
Zuyderland Medisch Centrum 1215 participants Est. completion 2029-03-31 1 siteOther conditions: Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI), Hypercholerolemia, Hypertension, Diabete Mellitus, Cardiovascular Risk ManagementView official trial listing → -
Recruiting NCT NCT07776054
Clinical Impact of SGLT2 Inhibitor After DC Cardioversion in Persistent AF With HFpEF
Not yet reported Samsung Medical Center 200 participants Est. completion 2027-09-01 1 site Stand-aloneOther conditions: Atrial Fibrillation, SGLT2 Inhibitor, DC CardioversionView official trial listing → -
Completed NCT NCT00297180
Weight Loss In Obese Subjects Taking Either GW869682 Or Placebo 3 Times Per Day For 12 Weeks
Not yet reported GlaxoSmithKline 136 participants Est. completion 2006-09 3 sitesOther conditions: ObesityView official trial listing → -
Completed NCT NCT00558571
4 Week Treatment With Three Oral Doses of BI 10773 in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 78 participants 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00642278
An Efficacy, Safety, and Tolerability Study of Canagliflozin (JNJ-28431754) in Patients With Type 2 Diabetes
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 451 participants Est. completion 2009-01 78 sitesOther conditions: Diabetes Mellitus, Type II, Diabetes Mellitus, Non Insulin DependentView official trial listing → -
Completed NCT NCT00749190
BI 10773 add-on to Metformin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 495 participants 116 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00789035
12 Weeks Treatment With 3 Different Doses of BI 10773 in Type 2 Diabetic Patients
Not yet reported Boehringer Ingelheim 408 participants 74 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00836225
Safety, Tolerability and Activity Study of Multiple Doses of ISIS-SGLT2Rx in Healthy Volunteers
Not yet reported Ionis Pharmaceuticals, Inc. 103 participants Est. completion 2012-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00854113
Study to Determine the Safety, Tolerability, and Pharmacokinetic (PK) Profile of EGT0001474 in Healthy Volunteers
Not yet reported Theracos 78 participants Est. completion 2009-07 1 siteOther conditions: Safety and Tolerability of EGT0001474 in Healthy VolunteersView official trial listing → -
Completed NCT NCT00881530
Empagliflozin (BI 10773) in Type Two Diabetes (T2D) Patients, Open Label Extension
Not yet reported Boehringer Ingelheim 660 participants 137 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00885118
4 Weeks Treatment With Empagliflozin (BI 10773) in Japanese Type 2 Diabetic Patients (T2DM)
Not yet reported Boehringer Ingelheim 100 participants 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT00924053
Safety, Tolerability and Pharmacokinetics Study of EGT0001474 in Subjects With Type 2 Diabetes
Not yet reported Theracos 24 participants Est. completion 2009-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT00963768
A Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of JNJ-28431754 in Patients With Type 2 Diabetes Mellitus
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 116 participants Est. completion 2007-12 3 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01001962
Double Blind Placebo Study of JARDIANCE® (Empagliflozin) in Prehypertensives Type II Diabetics
Not yet reported Aristotle University Of Thessaloniki 1054 participants Est. completion 2020-01 1 siteOther conditions: Hypertension, Type II DiabetesView official trial listing → -
Completed NCT NCT01011868
Efficacy and Safety of BI 10773 in Combination With Insulin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 494 participants 99 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01022112
An Efficacy, Safety, and Tolerability Study for TA-7284 in Patients With Type 2 Diabetes
Not yet reported Tanabe Pharma Corporation 383 participants Est. completion 2010-09 6 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01029704
Safety and Efficacy Study of EGT0001442 in Subjects With Type 2 Diabetes Mellitus
Not yet reported Theracos 151 participants Est. completion 2010-07 12 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01111318
Pharmacokinetics of Empagliflozin (BI 10773) in Patients With Impaired Liver Function
Not yet reported Boehringer Ingelheim 36 participants 1 siteOther conditions: Hepatic Insufficiency, HealthyView official trial listing → -
Completed NCT NCT01111331
Drug Drug Interaction of Empagliflozin (BI 10773) and Warfarin in Healthy Volunteers
Not yet reported Boehringer Ingelheim 18 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01131676
BI 10773 (Empagliflozin) Cardiovascular Outcome Event Trial in Type 2 Diabetes Mellitus Patients (EMPA-REG OUTCOME).
Not yet reported Boehringer Ingelheim 7064 participants Est. completion 2015-04 615 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01159600
Efficacy and Safety Study With Empagliflozin (BI 10773) vs. Placebo as add-on to Metformin or Metformin Plus Sulfonylurea Over 24 Weeks in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 1504 participants 148 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01164501
Efficacy and Safety of Empagliflozin (BI 10773) in Patients With Type 2 Diabetes and Renal Impairment
Not yet reported Boehringer Ingelheim 741 participants Est. completion 2012-07 127 sitesType 2 diabetes Other conditions: Renal InsufficiencyView official trial listing → -
Completed NCT NCT01167881
Efficacy and Safety of Empagliflozin (BI 10773) With Metformin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 1549 participants Est. completion 2015-08 182 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01177813
Efficacy and Safety of Empagliflozin (BI 10773) Versus Placebo and Sitagliptin Over 24 Weeks in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 986 participants 124 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01189201
Rel. BA of Empagliflozin (BI 10773)/Linagliptin FDC Tbl, Comparison With Mono-components, With a Second FDC Tablet and Influence of Food
Not yet reported Boehringer Ingelheim 42 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01193218
Empagliflozin (BI 10773) Dose Finder Study in Japanese Patients With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 547 participants Est. completion 2012-06 32 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01195675
Assessment of the Effect of Empagliflozin (BI 10773) as Single Dose on the QT Interval in Healthy Female and Male Subjects
Not yet reported Boehringer Ingelheim 30 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01210001
Efficacy and Safety of Empagliflozin (BI 10773) in Type 2 Diabetes Patients on a Background of Pioglitazone Alone or With Metformin
Not yet reported Boehringer Ingelheim 499 participants 68 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01211197
Bioavailability of a Fixed Dose Combination Tablet With Empagliflozin (BI 10773) and Metformin Compared With the Monocomponents and Effect of Food on Bioavailability
Not yet reported Boehringer Ingelheim 16 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01242176
Relative Bioavailability of Empagliflozin (BI 10773) (Final Formulation) Compared to Empagliflozin (BI 10773 XX) (Trial Formulation 2) in Healthy Male and Female Volunteers
Not yet reported Boehringer Ingelheim 24 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01248364
A Study to Determine Acute (After First Dose) and Chronic (After 28 Days) Effects of Empagliflozin (BI 10773) on Pre and Postprandial Glucose Homeostasis in Patients With Impaired Glucose Tolerance and Type 2 Diabetes Mellitus and Healthy Subjects
Not yet reported Boehringer Ingelheim 91 participants Est. completion 2013-07 3 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT01257334
Patients With Type 2 Diabetes Mellitus With Insufficient Glycaemic Control Despite Treatment With Metformin Alone or Metformin in Combination With a Sulfonylurea
Not yet reported Taipei Medical University WanFang Hospital 1390 participants Est. completion 2012-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01276288
Pharmacodynamics and Pharmacokinetics of Empagliflozin and Torasemide in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 23 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01276301
DDI Between BI Empagliflozin (10773) and Verapamil
Not yet reported Boehringer Ingelheim 16 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01284621
Relative Bioavailability of Empagliflozin (BI 10773) and Ramipril Administered Together Compared to Empagliflozin (BI 10773) and Ramipril Alone in Healthy Volunteers
Not yet reported Boehringer Ingelheim 23 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01289990
Safety and Efficacy of Empagliflozin (BI 10773) and Sitagliptin Versus Placebo Over 76 Weeks in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 2705 participants Est. completion 2013-05 243 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01301742
Relative Bioavailability of Single Dose Empagliflozin (BI 10773) When Co-administered With Multiple Doses of 600 mg Gemfibrozil Compared to Single Dose Treatment With Empagliflozin (BI 10773) When Given Alone in Healthy Volunteers
Not yet reported Boehringer Ingelheim 18 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01304329
Drug-drug Interaction of Empagliflozin (BI 10773) and Simvastatin
Not yet reported Boehringer Ingelheim 18 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01306175
Drug Interaction Study of Digoxin and BI 10773
Not yet reported Boehringer Ingelheim 20 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01306214
Safety and Efficacy of BI 10773 as add-on to Insulin Regimen in Patients With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 566 participants Est. completion 2013-04 103 sitesType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT01316341
Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Empagliflozin in Chinese Female and Male Patients With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 24 participants 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01328184
Drug-drug Interaction of Empagliflozin (BI 10773) and Microgynon
Not yet reported Boehringer Ingelheim 18 participants 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01368081
Empagliflozin (BI 10773) Comprehensive add-on Study in Japanese Subjects With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 1162 participants Est. completion 2013-04 87 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01370005
12 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Patients With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 825 participants Est. completion 2012-07 120 sitesType 2 diabetes Other conditions: HypertensionView official trial listing → -
Completed NCT NCT01387737
Long-Term Safety Study of TA-7284 in Patients With Type 2 Diabetes Mellitus
Not yet reported Tanabe Pharma Corporation 1299 participants Est. completion 2012-12 7 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01392560
Safety and Efficacy of Empagliflozin (BI 10773) in Type 1 Diabetes Mellitus Patients With or Without Renal Hyperfiltration
Not yet reported Boehringer Ingelheim 52 participants Est. completion 2012-08 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01413204
Efficacy and Safety Study of TA-7284 in Patients With Type 2 Diabetes
Not yet reported Tanabe Pharma Corporation 272 participants Est. completion 2012-08 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01422876
Efficacy and Safety of Empagliflozin (BI 10773) / Linagliptin (BI 1356) Fixed Dose Combination in Treatment naïve and Metformin Treated Type 2 Diabetes Patients
Not yet reported Boehringer Ingelheim 1405 participants Est. completion 2013-09 211 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01451775
Investigation of the Effect of Food on the Bioavailability of a 25 mg Empagliflozin Tablet as Well as Assessment of Dose Proportionality Between 10 mg and 25 mg Empagliflozin Tablets Under Fasting Conditions.
Not yet reported Boehringer Ingelheim 18 participants 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01512849
A Study to Evaluate the PK/PD and Safety of TA-7284 in Patients With Type 2 Diabetes Mellitus Who Have Moderate Renal Impairment
Not yet reported Tanabe Pharma Corporation 24 participants Est. completion 2012-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01581658
Renal Impairment Study of Empagliflozin (BI10773) in Japanese Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2012-11-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01634100
Drug-interaction Trial in Healthy Subjects With Oral Administration of Empagliflozin (BI 10773), Rifampicin and Probenecid
Not yet reported Boehringer Ingelheim 18 participants Est. completion 2012-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01649297
A 16 Weeks Study on Efficacy and Safety of Two Doses of Empagliflozin (BI 10773) (Once Daily Versus Twice Daily) in Patients With Type 2 Diabetes Mellitus and Preexisting Metformin Therapy
Not yet reported Boehringer Ingelheim 983 participants Est. completion 2013-12 139 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01672788
Demonstration of Bioequivalence of Empagliflozin and Metformin Given in One Tablet Compared to the Intake of Single Tablets
Not yet reported Boehringer Ingelheim 36 participants Est. completion 2012-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01719003
Safety and Efficacy Study of Empagliflozin and Metformin for 24 Weeks in Treatment Naive Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 1413 participants Est. completion 2014-12 190 sites Stand-aloneType 2 diabetes Other conditions: HyperglycemiaView official trial listing → -
Completed NCT NCT01734785
Safety and Efficacy of the Combination of Empagliflozin and Linagliptin Compared to Linagliptin Alone Over 24 Weeks in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 607 participants Est. completion 2015-03-23 90 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01778049
Linagliptin as Add on Therapy to Empagliflozin 10 mg or 25 mg With Background Metformin in Patient With Type 2 Diabetes
Not yet reported Boehringer Ingelheim 708 participants Est. completion 2015-03 114 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01811953
Equivalence of Resorption of Empagliflozin/Metformin Administered as Combination Tablet Compared With Empagliflozin/Metformin as Single Tablets Administered Together
Not yet reported Boehringer Ingelheim 48 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01844531
Bioequivalence of Empagliflozin and Metformin Given as a Fixed Dose Combination Compared to Single Tablets
Not yet reported Boehringer Ingelheim 24 participants Est. completion 2013-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01867307
Effect of Empagliflozin Kinetics on Renal Glucose Reabsorption in Patients With Type II Diabetes and Healthy Controls
Not yet reported Boehringer Ingelheim 39 participants Est. completion 2015-10 1 site Stand-aloneType 2 diabetes Other conditions: HealthyView official trial listing → -
Completed NCT NCT01907113
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BI 10773 in Type II Diabetes Patients With Different Degrees of Renal Impairment
Not yet reported Boehringer Ingelheim 40 participants Est. completion 2009-12 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT01924767
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Doses of BI 10773 Tablets
Not yet reported Boehringer Ingelheim 48 participants Est. completion 2007-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT01947855
Post Prandial Glucose (PPG) Study of Empagliflozin in Japanese Patients With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 60 participants Est. completion 2013-12 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT01969747
Empagliflozin add-on to Insulin in Type 1 Diabetes Mellitus Over 28 Days
Not yet reported Boehringer Ingelheim 75 participants Est. completion 2014-04 2 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT01975220
Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Compared With Single Tablets
Not yet reported Boehringer Ingelheim 72 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT01984606
Efficacy and Safety of Empagliflozin Versus Sitagliptin in Patients With Type 2 Diabetes
Not yet reported Boehringer Ingelheim Est. completion 2017-02 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02028767
Bioequivalence Study in Healthy Volunteers for Empagliflozin/Metformin Fixed Dose Combination Compared to Separate Tablets
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2014-02 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02041234
Roux-en-Y Gastric Bypass for BMI 27-32 Type 2 Diabetes Versus Best Medical Treatment
Not yet reported Khoo Teck Puat Hospital 40 participants Est. completion 2022-06 1 siteOther conditions: Type II Diabetes in Subjects BMI 27 to 32View official trial listing → -
Completed NCT NCT02102932
Bioavailability of Empagliflozin/Metformin Fixed Dose Combinations (FDCs) in Healthy Chinese Volunteers
Not yet reported Boehringer Ingelheim 96 participants Est. completion 2014-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02105792
PROMASTER - PROspective Cohort MRC ABPI STratification and Extreme Response Mechanism in Diabetes
Royal Devon and Exeter NHS Foundation Trust 820 participants Est. completion 2016-05 5 sitesOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02106923
Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Extended Release (XR) Compared With Single Tablets
Not yet reported Boehringer Ingelheim 72 participants Est. completion 2014-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02109978
RetroMASTER - Retrospective Cohort MRC ABPI STratification and Extreme Response Mechanism in Diabetes
Royal Devon and Exeter NHS Foundation Trust 562 participants Est. completion 2015-05 3 sitesOther conditions: DiabetesView official trial listing → -
Completed NCT NCT02121483
Pharmacokinetic Single Dose Trial of Empagliflozin in Children and Adolescents With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 27 participants Est. completion 2016-02 11 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02172170
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Oral Doses of BI 10773 in Healthy Male Subjects
Not yet reported Boehringer Ingelheim 72 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02172196
Bioavailability of BI 10773 and Sitagliptin in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 16 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02172209
Bioavailability and Pharmacokinetics of BI 10773 Tablet in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 14 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02172222
Relative Bioavailability of BI 10773 and Linagliptin in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 16 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02172235
Relative Bioavailability of Pioglitazone After Co-administration With Different Doses of BI 10773 in Healthy Volunteers
Not yet reported Boehringer Ingelheim 20 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02172248
Relative Bioavailability BI 10773 and Metformin in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 16 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02172261
Relative Bioavailability of BI 10773 and Glimepiride in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 16 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02172274
BI 10773 Administered as Oral Solution to Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 8 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02175784
A Study to Assess the Efficacy and Safety of Ipragliflozin in Combination With Insulin in Subjects With Type 2 Diabetes Mellitus
Not yet reported Astellas Pharma Inc 262 participants Est. completion 2015-12-07 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02182453
Single Rising Oral Doses of BI 10773 in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 48 participantsOther conditions: HealthyView official trial listing → -
Completed NCT NCT02182830
24 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Black/African American Patients With Type 2 Diabetes Mellitus and Hypertension
Not yet reported Boehringer Ingelheim 166 participants Est. completion 2017-05-18 92 sites Stand-aloneType 2 diabetes Other conditions: HypertensionView official trial listing → -
Completed NCT NCT02221284
Alogliptin Tablets Specified Drug-use Survey "Type 2 Diabetic Patients Receiving Combination Therapy With a Hypoglycemic Agent (e.g., Insulin Preparations or Rapid-acting Insulin Secretagogues)"
Takeda 964 participants Est. completion 2017-06-30 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02230995
Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Subjects
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02266472
Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Metformin Extended Release Compared With Mono Compound Tablets in Healthy Male and Female
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02276365
Bioavailability of BI 10773 and Pioglitazone in Healthy Male Volunteers
Not yet reported Boehringer Ingelheim 20 participantsOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02284269
Meta-analysis in Post-marketing Surveillances for SGLT2 Inhibitors in Patients With Type 2 Diabetes Mellitus
Pharmaceuticals and Medical Devices Agency, Japan 18000 participantsType 2 diabetesView official trial listing → -
Completed NCT NCT02297620
The Survey of Ipragliflozin Treatment in Elderly type2 Diabetes Patients
Astellas Pharma Inc 8687 participants Est. completion 2015-07 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02317484
Investigation for Clinical Efficacy and Safety of Ipragliflozin 50mg and 100mg on Type II Diabetes
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan 231 participants Est. completion 2018-02-28 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02324842
Effect of Combined Incretin-Based Therapy Plus Canagliflozin on Glycemic Control and the Compensatory Rise in Hepatic Glucose Production in Type 2 Diabetic Patients
Not yet reported The University of Texas Health Science Center at San Antonio 45 participants Est. completion 2019-03-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02338921
Triple Combination Therapy in Type 2 Diabetic Patients Who Had Inadequate Glycemic Control With Combination Therapy
Not yet reported Seoul National University Bundang Hospital 78 participants Est. completion 2021-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02367131
Daily Use of JARDIANCE® Tablets in Japanese Elderly Patients With Type 2 Diabetes Mellitus
Boehringer Ingelheim 419 participants Est. completion 2016-09-27 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02397421
Safety and Effectiveness of SGLT-2 Inhibitors in Patients With Heart Failure and Diabetes
Not yet reported University of Dundee 56 participants Est. completion 2017-08 1 siteHeart failure Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02401880
Effects of Linagliptin in Addition to Empagliflozin on Islet Cell Physiology
Not yet reported Profil Institut für Stoffwechselforschung GmbH 89 participants Est. completion 2015-12 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02404870
Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy Volunteers
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 67 participants Est. completion 2019-09-03 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Completed NCT NCT02414958
Empagliflozin as Adjunctive to InSulin thErapy Over 52 Weeks in Patients With Type 1 Diabetes Mellitus (EASE-2)
Not yet reported Boehringer Ingelheim 730 participants Est. completion 2017-10-23 131 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02433678
An Investigation Into The Anti-hypertensive And Potential Anti-inflammatory Actions Of Dapagliflozin
Not yet reported University at Buffalo 52 participants Est. completion 2018-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02453555
Empagliflozin Add on to Linagliptin Study in Japanese Patient With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 275 participants Est. completion 2017-03-27 40 sites Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT02462421
Pharmacogenetics of SGLT2 Inhibitors
Not yet reported University of Maryland, Baltimore 30 participants Est. completion 2021-12-31Other conditions: Diabetes Mellitus, Gout, HyperuricemiaView official trial listing → -
Completed NCT NCT02471963
Effect of Empagliflozin on Macrovascular and Microvascular Circulation and on Endothelium Function
Not yet reported University of Erlangen-Nürnberg Medical School 74 participants Est. completion 2016-06 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02479399
Specified Drug Use Results Survey of Ipragliflozin Treatment in type2 Diabetes Patients
Astellas Pharma Inc 11412 participants Est. completion 2018-10-16 8 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02489942
Long Term Daily Use of JARDIANCE® Tablets in Japanese Patients With Type 2 Diabetes Mellitus
Boehringer Ingelheim 8145 participants Est. completion 2020-12-04 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02489968
Linagliptin as Add on Therapy to Empagliflozin 10 mg or 25 mg With Japanese Patients With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 880 participants Est. completion 2017-06-16 83 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02500186
The Clinical Study to Assess the Effect of the Amount of Carbohydrate Intake and Meals Differing in Glycemic Index (GI) in Patients Treated With a Sodium-dependent Glucose Cotransporter 2 (SGLT2) Inhibitor
Not yet reported Kansai Electric Power Hospital 24 participants Est. completion 2015-12Other conditions: Diabetes Melltius, Type 2View official trial listing → -
Status unknown NCT NCT02501616
Effect of Dapagliflozine on Systemic and Renal Endothelial Function
Not yet reported Seoul National University Hospital 22 participants 1 siteType 2 diabetes Other conditions: Endothelial FunctionView official trial listing → -
Completed NCT NCT02518945
Dapagliflozin As Additional Treatment To Liraglutide And Insulin In Patients With Type 1 Diabetes
Not yet reported University at Buffalo 26 participants Est. completion 2016-04 1 siteOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT02528019
Metabolic and Cardiovascular Effects of Dipeptidyl Peptidase-4 (DPP-4) or Sodium-glucose Co-transporter Type 2 (SGLT2) Inhibitors
Not yet reported Kurume University 100 participants Est. completion 2018-08 1 siteOther conditions: Effects of the DPP-4 Inhibitors or SGLT2 Inhibitors on the Protective Actions for Diabetic ComplicationsView official trial listing → -
Completed NCT NCT02529449
Pharmacodynamics, Pharmacokinetics, and Safety of ASP1941 in Patients With Type 1 Diabetes Mellitus
Not yet reported Astellas Pharma Inc 43 participants Est. completion 2016-03-19 11 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT02577159
Dapagliflozin on Hyperlipidemia and Insulin Resistance in Type 2 Diabetic Patients (DAPHNIS Study)
Not yet reported Osaka University 50 participants Est. completion 2018-08-31 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02577315
Demonstrate Bioequivalence of Two 12.5 mg Empagliflozin/500 mg Metformin Fixed Dose Combination Tablets With Free Combination of Empagliflozin 25 mg and Metformin 1000 mg in Healthy Male and Female Volunteers Under Fed Conditions
Not yet reported Boehringer Ingelheim 25 participants Est. completion 2015-10 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02578563
Prospective Diabetes Registry of Patients With Type 2 Diabetes Mellitus on SGLT 2 Inhibitor Therapy in Singapore
AstraZeneca 201 participants Est. completion 2018-12-31 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT02580591
Empagliflozin as Adjunctive to Insulin Therapy Over 26 Weeks in Patients With T1DM (EASE-3)
Not yet reported Boehringer Ingelheim 977 participants Est. completion 2017-09-20 189 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT02589626
Long-term Safety and Efficacy of Empagliflozin as Add on to GLP-1 RA
Not yet reported Boehringer Ingelheim 65 participants Est. completion 2017-06-02 16 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02589639
Efficacy and Safety Study of Empagliflozin as add-on to Insulin in Japanese Patients With Type 2 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 269 participants Est. completion 2018-01-05 48 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02592421
SGLT2 Inhibition and Stimulation of Endogenous Glucose Production: Protocol 2
Not yet reported The University of Texas Health Science Center at San Antonio 30 participants Est. completion 2019-10-31 1 siteOther conditions: Type II Diabetes MellitusView official trial listing → -
Completed NCT NCT02597049
A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus
Not yet reported Eli Lilly and Company 424 participants Est. completion 2017-02 41 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02616666
A Pragmatic Randomized Trial to Evaluate the Comparative Effectiveness Between Dapagliflozin and Standard of Care in Type 2 Diabetes Patients
Not yet reported University of Liverpool 632 participants Est. completion 2025-12-12 132 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02632747
Empagliflozin and ACEi- Effects on Hyperfiltration: BETWEEN Study
Not yet reported Boehringer Ingelheim 31 participants Est. completion 2019-07-02 1 site Stand-aloneType 2 diabetes Other conditions: Diabetes Mellitus, Type 1, ObesityView official trial listing → -
Completed NCT NCT02635386
EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)
Not yet reported Woman's 119 participants Est. completion 2020-10-09 1 siteOther conditions: Polycystic Ovary Syndrome, ObesityView official trial listing → -
Completed NCT NCT02636192
Study on Incidence of Diabetic Ketoacidosis Among Participants With Type 2 Diabetes Mellitus Treated With Sodium-glucose Co-transporter 2 (SGLT2) Inhibitors or Other Antihyperglycemic Agents
Janssen Research & Development, LLC 200000 participants Est. completion 2017-04-07Type 2 diabetesView official trial listing → -
Completed NCT NCT02637973
Effects of Empagliflozin on Liver Fat Content, Energy Metabolism and Body Composition in Patients With Type 2 Diabetes
Not yet reported The Deutsche Diabetes Forschungsgesellschaft e.V. 84 participants Est. completion 2018-08 5 sites Stand-aloneType 2 diabetes Other conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT02649465
SGLT2 Inhibitor Versus Sulfonylurea on Type 2 Diabetes With NAFLD
Not yet reported Kanazawa University 40 participants Est. completion 2021-06-30 1 siteOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT02653209
TriMaster: Study of a DPP4 Inhibitor, SGLT2 Inhibitor and Thiazolidinedione as Third Line Therapy in Patients With Type 2 Diabetes.
Not yet reported Royal Devon and Exeter NHS Foundation Trust 525 participants Est. completion 2021-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02653482
Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure
Not yet reported Saint Luke's Health System 263 participants Est. completion 2019-06-28 25 sitesHeart failureView official trial listing → -
Completed NCT NCT02686476
Effect of Empagliflozin on Liver Fat Content in Patients With Type 2 Diabetes
Not yet reported Medanta, The Medicity, India 100 participants Est. completion 2017-12 1 siteOther conditions: Non Alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT02695121
Cancer in Patients on Dapagliflozin and Other Antidiabetic Treatment
AstraZeneca 2133575 participants Est. completion 2025-01-30 4 sitesOther conditions: Breast Cancer, Bladder CancerView official trial listing → -
Completed NCT NCT02696941
SGLT2 Inhibitors and Metformin on Metabolism and Non-Alcoholic SteatoHepatitis
Not yet reported University of Oxford 20 participants Est. completion 2018-04-01 1 site Stand-aloneOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT02700334
Effect of Dapagliflozin on Insulin Secretion and Insulin Sensitivity in Patients With Prediabetes
Not yet reported University of Guadalajara 24 participants Est. completion 2017-02 1 sitePrediabetesView official trial listing → -
Completed NCT NCT02702011
Empa Add on to Insulin in Japanese Patient With Type 1 Diabetes Mellitus
Not yet reported Boehringer Ingelheim 48 participants Est. completion 2016-10-03 4 sites Stand-aloneOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT02719756
Effect of SGLT-2 Inhibitor Dapagliflozin on Glycemic Variability in Patients With Diabetes Mellitus Type 2
Not yet reported Research Clinical Centre of the Russian Railways, JSC 100 participants Est. completion 2016-12 1 siteOther conditions: Diabetes Mellitus, Hypoglycemic EpisodesView official trial listing → -
Terminated NCT NCT02728453
SGLT2 Inhibition and Left Ventricular Mass
Not yet reported Hannover Medical School 7 participants Est. completion 2017-09-27 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02729766
Effects of Empagliflozin an SGLT2-Inhibitor on Healthy Volunteers With Induced Hypotonic Hyponatremia - the DIVE Study
Not yet reported, Not yet reported University Hospital, Basel, Switzerland 15 participants Est. completion 2016-08 1 siteOther conditions: Inappropriate ADH SyndromeView official trial listing → -
Completed NCT NCT02730377
Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes
Not yet reported Novo Nordisk A/S 1991 participants Est. completion 2019-08-12 232 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02752113
Effects of Empagliflozin + Linagliptin vs Metformin + Insulin Glargine on Renal and Vascular Changes in Type 2 Diabetes
Not yet reported Institut für Pharmakologie und Präventive Medizin 101 participants Est. completion 2019-05 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02758171
Bioequivalence of a Fixed Dose Combination Tablet of Empagliflozin/Linagliptin Compared With the Free Combination of Empagliflozin Tablet and Linagliptin Tablet in Healthy Male and Female Subjects
Not yet reported Boehringer Ingelheim 56 participants Est. completion 2016-08-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT02768220
The Effect of Sodium-Glucose Cotransporter 2 Inhibitors on Advanced Glycation End Products
Not yet reported Northwell Health Est. completion 2018-12 Stand-aloneOther conditions: SGLT-2 Inhibitors, Advanced Glycation End Products, DiabetesView official trial listing → -
Completed NCT NCT02773368
A Clinical Trial Comparing Glycaemic Control and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Insulin Glargine (IGlar) as add-on Therapy to SGLT2i in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 420 participants Est. completion 2017-10-23 88 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02782624
Relative Bioavailability of BI 10773 Administered Twice Daily Compared BI 10773 Given Once Daily After Multiple Oral Doses in Healthy Male and Female Volunteers
Not yet reported Boehringer Ingelheim 16 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02787551
Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period
Not yet reported Sanofi 514 participants Est. completion 2018-11-17 124 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT02792400
The Role of Glucagon in the Effects of Dipeptidyl Peptidase-4 Inhibitors and Sodium-glucose Co-transporter-2 Inhibitors
Not yet reported University Hospital, Gentofte, Copenhagen 24 participants Est. completion 2018-07 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02796170
Inhibition of Urinary Angiotensinogen and the Reduction of Blood Pressure by SGLT2 Inhibition in Patients With Type 2 Diabetes
Not yet reported Tulane University School of Medicine 11 participants Est. completion 2020-08 1 siteType 2 diabetes Other conditions: HypertensionView official trial listing → -
Completed NCT NCT02798744
SGLT-2 Inhibitor Empagliflozin Effects on Appetite and Weight Regulation.
Not yet reported University of Leicester 68 participants Est. completion 2019-07-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02815644
Empa/Lina FDC Food Effect Study (Japan)
Not yet reported Boehringer Ingelheim 22 participants Est. completion 2016-10-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02821910
Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Linagliptin/Metformin Extended Release Compared With Single Tablets
Not yet reported Boehringer Ingelheim 50 participants Est. completion 2016-10-31 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT02833415
Visceral Adiposity and Diabetes: Translating Form to Function Using Imaging
Not yet reported University of Texas Southwestern Medical Center 40 participants Est. completion 2018-11 1 site Stand-aloneOther conditions: Obesity, VisceralView official trial listing → -
Completed NCT NCT02846233
Stepping-down Approach in Patients With Chronic Poorly-controlled Diabetes on Advanced Insulin Therapy?
Not yet reported University of California, San Francisco 22 participants Est. completion 2018-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02847091
Study of Ipragliflozin in Patients With Type 2 Diabetes Mellitus Receiving Insulin Therapy
Not yet reported Astellas Pharma Inc 103 participants Est. completion 2017-11-09 15 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT02848833
JARDIANCE Regulartory Post Marketing Surveillance in Korean Type 2 Diabetes Mellitus
Boehringer Ingelheim 3368 participants Est. completion 2020-04-17 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT02854748
Evaluate the Drug-drugs Interaction Between Lobeglitazone and Empagliflozin
Not yet reported Chong Kun Dang Pharmaceutical 30 participants Est. completion 2016-09 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT02857764
Sodium-glucose Co-transporter 2 (SGLT2) Inhibitor Risk of Below-Knee Lower Extremity Amputation: A Retrospective Cohort Study Using a Large Claims Database in the United States
Janssen Research & Development, LLC 127690 participants Est. completion 2017-06-30Type 2 diabetesView official trial listing → -
Completed NCT NCT02863328
Efficacy and Safety of Oral Semaglutide Versus Empagliflozin in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 822 participants Est. completion 2018-03-08 106 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02864914
Post-authorisation Safety Study in Patients With Type 2 Diabetes to Assess the Risk of Liver Injury, Kidney Injury, Urinary Tract and Genital Infections, and Diabetic Ketoacidosis in Patients Treated With Empagliflozin, Compared to DPP-4 Inhibitors
Boehringer Ingelheim 333580 participants Est. completion 2022-07-29 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02874807
Effects of the SGLT2-inhibitor Empagliflozin on Patients With SIADH - the SAND Study
Not yet reported, Not yet reported University Hospital, Basel, Switzerland 88 participants Est. completion 2019-01-14 1 siteOther conditions: SIADHView official trial listing → -
Completed NCT NCT02890745
The Effect Effect of Empagliflozin on Oxidative Stress in Patients With Type 2 Diabetes
Not yet reported Henrik Enghusen Poulsen 31 participants Est. completion 2020-01-22 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT02891954
Genetics of Response to Canagliflozin
Not yet reported University of Maryland, Baltimore 700 participants Est. completion 2026-12-25Type 2 diabetesView official trial listing → -
Completed NCT NCT02897219
A Study of ASP1941 in Combination With Insulin in Patients With Type 1 Diabetes Mellitus
Not yet reported Astellas Pharma Inc 175 participants Est. completion 2018-03-15 36 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT02911792
Effect of Farxiga on Renal Function and Size in Type 2 Diabetic Patients With Hyperfiltration
Not yet reported The University of Texas Health Science Center at San Antonio 72 participants Est. completion 2023-07-11 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT02914691
Effects of Dapagliflozin Treatment on Urinary Proteomic Patterns in Patients With Type 2 Diabetes
Not yet reported Peter Rossing 40 participants Est. completion 2017-07-05 1 siteType 2 diabetesChronic kidney diseaseView official trial listing → -
Status unknown NCT NCT02918591
Cardiovascular Effects of Empagliflozine
Not yet reported Tel Aviv University 10 participants Est. completion 2018-12Type 2 diabetesView official trial listing → -
Completed NCT NCT02920918
Treatment of Diabetes in Patients With Systolic Heart Failure
Not yet reported Virginia Commonwealth University 36 participants Est. completion 2018-09 1 siteHeart failureType 2 diabetesView official trial listing → -
Completed NCT NCT02932436
Effects of Empagliflozin on Left Ventricular Diastolic Function Compared to Usual Care in Type 2 Diabetics
Not yet reported Johannes Gutenberg University Mainz 144 participants Est. completion 2020-08-31 1 site Stand-aloneType 2 diabetes Other conditions: Diastolic DysfunctionView official trial listing → -
Completed NCT NCT02954692
A Study to Evaluate the Effectiveness and Safety Initiation and Titration of Insulin Glargine (U300) in Insulin-naïve Patients With Type 2 Diabetes Mellitus (T2DM) Controlled on Oral Antidiabetic Drug Treatment in Turkey
Not yet reported Sanofi 112 participants Est. completion 2017-12-22 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT02956811
Does Dapagliflozin Regress Left Ventricular Hypertrophy In Patients With Type 2 Diabetes?
Not yet reported University of Dundee 66 participants Est. completion 2019-04-02 1 siteType 2 diabetes Other conditions: Left Ventricular HypertrophyView official trial listing → -
Completed NCT NCT02964247
LIRA-ADD2SGLT2i - Liraglutide Versus Placebo as add-on to SGLT2 Inhibitors.
Not yet reported Novo Nordisk A/S 303 participants Est. completion 2018-05-08 82 sites Added to GLP-1Type 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT02964572
Effect of Sodium Glucose Co-transporter 2 Inhibitor on Inflammatory Cytokine in Type 2 Diabetes
Not yet reported Yonsei University 61 participants Est. completion 2017-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT02964715
The Effect of Empagliflozin on NAFLD in Asian Patients With Type 2 Diabetes
Not yet reported University of Malaya 25 participants Est. completion 2018-11 1 site Stand-aloneType 2 diabetesMASLDView official trial listing → -
Completed NCT NCT02966626
A Real World Experience of Dapagliflozin in Type 2 Diabetes
University of Malaya 223 participants Est. completion 2018-01Type 2 diabetesView official trial listing → -
Completed NCT NCT02973477
Dapagliflozin and Measures of Cardiovascular Autonomic Function in Patients With Type 2 Diabetes (T2D)
Not yet reported University of Michigan 45 participants Est. completion 2019-08-22 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Terminated NCT NCT02985242
Empagliflozin Reduces Progression of Diabetic Retinopathy in Patients With High Risk of Diabetic Macular Edema
Not yet reported Hannover Medical School 6 participants Est. completion 2018-08-16 1 site Stand-aloneOther conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT02993614
Comparative Effectiveness of Cardiovascular Outcomes in New Users of SGLT-2 Inhibitors
AstraZeneca 99999 participants Est. completion 2020-12-17 17 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT02998970
Effects of Empagliflozin on Cardiac Structure in Patients With Type 2 Diabetes
Not yet reported Unity Health Toronto 97 participants Est. completion 2018-09 1 siteCardiovascular disease Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03007329
Effects of Combined Dapagliflozin and Exenatide Versus Dapagliflozin and Placebo on Ectopic Lipids in Patients With Uncontrolled Type 2 Diabetes Mellitus.
Not yet reported Medical University of Vienna 34 participants Est. completion 2020-01-16 1 siteType 2 diabetes Other conditions: Steatosis, LiverView official trial listing → -
Completed NCT NCT03008551
Empagliflozin vs Metformin in PCOS
Not yet reported, Not yet reported Hull University Teaching Hospitals NHS Trust 40 participants Est. completion 2018-04-02 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT03027960
Empagliflozin in Heart Failure: Diuretic and Cardio-Renal Effects
Not yet reported Yale University 21 participants Est. completion 2019-06-01 1 site Stand-aloneHeart failure Other conditions: Type II; DiabetesView official trial listing → -
Completed NCT NCT03030222
Empagliflozin Impact on Hemodynamics in Patients With Heart Failure
Not yet reported Saint Luke's Health System 65 participants Est. completion 2020-03-10 10 sitesHeart failureView official trial listing → -
Completed NCT NCT03030235
Dapagliflozin in PRESERVED Ejection Fraction Heart Failure
Not yet reported Saint Luke's Health System 324 participants Est. completion 2021-08-13 26 sitesHeart failureView official trial listing → -
Completed NCT NCT03050229
SGLT-2i and ARB Combination Therapy in Patients With T2DM and Nocturnal Hypertension (SACRA Study)
Not yet reported Jichi Medical University 174 participants Est. completion 2018-03 12 sites Stand-aloneType 2 diabetes Other conditions: Nocturnal HypertensionView official trial listing → -
Completed NCT NCT03050619
Characteristics of Empagliflozin Initiators
Boehringer Ingelheim 31908 participants Est. completion 2016-10-14 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03057951
EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved)
Not yet reported Boehringer Ingelheim 5988 participants Est. completion 2021-04-26 619 sites Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT03057977
EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced)
Not yet reported Boehringer Ingelheim 3730 participants Est. completion 2020-05-28 520 sites Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT03059056
Pharmacokinetic Evaluation of Empagliflozin
Not yet reported British University In Egypt 6 participants Est. completion 2017-02-02 Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT03060980
Comparison of Efficacy, Safety, and Tolerability of ITCA 650 to Empagliflozin and Glimepiride as add-on Metformin
Not yet reported Intarcia Therapeutics 245 participants Est. completion 2018-01-26 101 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03078101
EMPRA (EMPagliflozin and RAs in Kidney Disease)
Not yet reported Medical University of Vienna 51 participants Est. completion 2019-08-07 1 site Stand-aloneChronic kidney diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT03086330
Efficacy and Safety of Semaglutide Once-weekly Versus Placebo as add-on to SGLT-2i in Subjects With Type 2 Diabetes Mellitus
Not yet reported Novo Nordisk A/S 302 participants Est. completion 2018-08-06 72 sitesType 2 diabetes Other conditions: DiabetesView official trial listing → -
Completed NCT NCT03087773
Impact of EMpagliflozin on Cardiac Function and Biomarkers of Heart Failure in Patients With Acute MYocardial Infarction
Not yet reported Medical University of Graz 476 participants Est. completion 2022-05-17 11 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT03089333
Effects of SGLT2 Inhibitor on Hemodynamic Parameters in Resistant Hypertensive Subjects
Not yet reported University of Campinas, Brazil 16 participants Est. completion 2017-12 1 siteType 2 diabetes Other conditions: Hypertension, Blood Pressure, Obesity, Cardiac Hypertrophy, Microalbuminuria, Vascular StiffnessView official trial listing → -
Completed NCT NCT03093103
Empagliflozin and Renal Oxygenation in Healthy Volunteers
Not yet reported Centre Hospitalier Universitaire Vaudois 45 participants Est. completion 2018-12-31 1 siteOther conditions: NephropathyView official trial listing → -
Completed NCT NCT03113110
Empagliflozin in Post-Transplantation Diabetes Mellitus
Not yet reported Medical University of Vienna 16 participants Est. completion 2018-05-31 1 siteOther conditions: Posttransplant Diabetes MellitusView official trial listing → -
Completed NCT NCT03118336
Impact of Empaglifozine on Cardiac Ectopic Fat
Not yet reported Assistance Publique Hopitaux De Marseille 56 participants Est. completion 2020-02-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03122834
Effect of Genetic Polymorphism on the Clinical Outcome of Patients With Heart Failure
Ain Shams University 246 participants Est. completion 2024-06-14 1 siteHeart failureView official trial listing → -
Completed NCT NCT03128528
Analysing the Effect of Empagliflozin on Reduction of Tissue Sodium Content in Patients With Chronic Heart Failure
Not yet reported University of Erlangen-Nürnberg Medical School 84 participants Est. completion 2020-04-30 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT03131232
The Effect of Empagliflozin on Glucose Metabolism, Weight, Blood Pressure and Cardiac Function (NT-proBNP) Should be Investigated
RWTH Aachen University 46 participants Est. completion 2017-12-31Type 2 diabetesView official trial listing → -
Completed NCT NCT03132181
Empagliflozin as a Modulator of Systemic Vascular Resistance and Cardiac Output in Patients With Type 2 Diabetes
Not yet reported RWTH Aachen University 40 participants Est. completion 2019-01-23 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03151343
SGLT-2 Inhibitor and Myocardial Perfusion, Function and Metabolism in T2 DM Patients at High Cardiovascular Risk
Not yet reported Caroline M Kistorp 92 participants Est. completion 2020-05-22 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT03152552
A Dose Finding Study to Assess the Effect of LIK066 Compared to Placebo or Empagliflozin in Patients With Type 2 Diabetes Mellitus and Heart Failure
Not yet reported Novartis Pharmaceuticals 125 participants Est. completion 2018-06-06 106 sitesHeart failureView official trial listing → -
Completed NCT NCT03157414
Empagliflozin in Renal Transplant Recipients
Not yet reported Oslo University Hospital 49 participants Est. completion 2018-06-28 1 siteOther conditions: Diabetes Mellitus, Renal Insufficiency, Safety IssuesView official trial listing → -
Completed NCT NCT03168295
PROTOCOL 3: Role of the Renal Nerves in the Increase in EGP in Response to Glucosuria
Not yet reported The University of Texas Health Science Center at San Antonio 34 participants Est. completion 2019-05-15 1 site Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT03173963
Empaglifozin in Early Diabetic Kidney Disease
Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Est. completion 2020-02-21 1 siteChronic kidney diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT03178591
Effects of DPP4 Inhibitor Versus SGLT2 Inhibitor
Not yet reported Chiang Mai University 43 participants Est. completion 2018-07 1 siteType 2 diabetes Other conditions: Ischemic Heart DiseaseView official trial listing → -
Completed NCT NCT03188887
Treatment of IgA Nephropathy According to Renal Lesions
Not yet reported Assistance Publique - Hôpitaux de Paris 62 participants Est. completion 2024-01-12 1 site Stand-aloneOther conditions: IgA NephropathyView official trial listing → -
Completed NCT NCT03190694
Effects of Dapagliflozin in Non-diabetic Patients With Proteinuria
Not yet reported Hiddo Lambers Heerspink 53 participants Est. completion 2019-12-01 7 sitesChronic kidney disease Other conditions: ProteinuriaView official trial listing → -
Withdrawn NCT NCT03190798
Effects of Canagliflozin on Intravascular Volume and Hemodynamics
Not yet reported The University of Texas Health Science Center at San Antonio Est. completion 2018-08-01 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT03193684
Empagliflozin and Hepatic Glucose Metabolism
Not yet reported The University of Texas Health Science Center at San Antonio 72 participants Est. completion 2024-01-30 1 site Stand-aloneOther conditions: Hepatic Glucose MetabolismView official trial listing → -
Completed NCT NCT03198585
Empagliflozin in Heart Failure Patients With Reduced Ejection Fraction
Not yet reported Morten Schou 190 participants Est. completion 2020-01-17 2 sitesHeart failureView official trial listing → -
Completed NCT NCT03200782
Postprandial Hypoglycemia in Patients After Bariatric Surgery With Empagliflozin and Anakinra - The Hypo-BEAR-Study
Not yet reported University Hospital, Basel, Switzerland 12 participants Est. completion 2018-09-21 1 siteOther conditions: Postprandial Hypoglycemia, Bariatric Surgery, Late Dumping SyndromeView official trial listing → -
Completed NCT NCT03200860
Effects of Empagliflozin on Clinical Outcomes in Patients With Acute Decompensated Heart Failure
Not yet reported University Medical Center Groningen 80 participants Est. completion 2019-09-18 5 sitesHeart failureView official trial listing → -
Completed NCT NCT03202667
Effects of the SGLT2-inhibitor Empagliflozin on Patients With Chronic SIADH - the SANDx Study
Not yet reported, Not yet reported University Hospital, Basel, Switzerland 17 participants Est. completion 2021-12-06 1 siteOther conditions: SIAD - Syndrome of Inappropriate Antidiuresis, HyponatremiaView official trial listing → -
Status unknown NCT NCT03204799
Metagenomic Analysis of Human Gut Microbiota in Patients With Metabolic Diseases Including Diabetes
Yonsei University 150 participants Est. completion 2019-12-16 1 siteType 2 diabetes Other conditions: DyslipidemiasView official trial listing → -
Completed NCT NCT03208465
Empagliflozin Versus Sitagliptin Therapy for Improvement of Myocardial Perfusion Reserve in Diabetic Patients With Coronary Artery Disease
Not yet reported CHEOL WHAN LEE, M.D., Ph.D 100 participants Est. completion 2019-08-01 1 site Stand-aloneOther conditions: Diabetes Mellitus, Coronary DiseaseView official trial listing → -
Completed NCT NCT03214380
A Study of LY900014 Compared to Insulin Lispro in Participants With Type 2 Diabetes
Not yet reported Eli Lilly and Company 933 participants Est. completion 2019-03-13 141 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03215069
Empagliflozin and the Preservation of Beta-cell Function in Women with Recent Gestational Diabetes
Not yet reported Mount Sinai Hospital, Canada 91 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Gestational DiabetesView official trial listing → -
Completed NCT NCT03226457
SGLT2 Inhibition in Combination With Diuretics in Heart Failure
Not yet reported University of Dundee 23 participants Est. completion 2019-01-09 1 siteHeart failureType 2 diabetesView official trial listing → -
Completed NCT NCT03227484
Effect of Empagliflozin Versus Placebo on Brain Insulin Sensitivity in Patients With Prediabetes
Not yet reported University Hospital Tuebingen 42 participants Est. completion 2019-11-18 1 sitePrediabetes Other conditions: Body WeightView official trial listing → -
Completed NCT NCT03233178
Measurement of Alanine Aminotransaminase (ALT) Following Initiation of Antidiabetic Agents in Patients With Type 2 Diabetes in a Real-world Clinical Setting: a Retrospective Cohort Study
LMC Diabetes & Endocrinology Ltd. 4000 participants Est. completion 2017-06 1 siteType 2 diabetesMASLD Other conditions: Fatty LiverView official trial listing → -
Completed NCT NCT03249506
Cardiovascular Outcomes in Participants With Type 2 Diabetes Mellitus (T2DM)
Janssen Research & Development, LLC 25358 participants Est. completion 2017-11-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03254849
Empagliflozin and Sympathetic Nerve Traffic
Not yet reported Profil Institut für Stoffwechselforschung GmbH 75 participants Est. completion 2020-04-20 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03259490
This Study Tests Whether Taking the Medicines Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills. The Study is Done in Healthy Men and Women and Measures the Amount of Each Medicine in the Blood
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2017-11-13 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT03267576
An Efficacy Study of Canagliflozin or Sitagliptin to Determine Glucose Variability in Mexican Participants With Type 2 Diabetes Mellitus Inadequately Controlled on Metformin
Not yet reported Janssen Research & Development, LLC 64 participants Est. completion 2018-10-01 5 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT03271879
Empagliflozin Versus Placebo on the Rate of Arrhythmic Events in Heart Failure Patients
Not yet reported Rambam Health Care Campus 128 participants Est. completion 2020-06-01Heart failure Other conditions: Diabetes Mellitus, ArrythmiaView official trial listing → -
Completed NCT NCT03282136
SGLT2i and Incretin and CRTd.
Not yet reported University of Campania Luigi Vanvitelli 500 participants Est. completion 2024-09-01 1 siteType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT03316131
A Study to Assess the Effect of Intensive Uric Acid (UA) Lowering Therapy With RDEA3170, Febuxostat, Dapagliflozin on Urinary Excretion of UA
Not yet reported AstraZeneca 36 participants Est. completion 2018-07-19 2 sitesOther conditions: Asymptomatic HyperuricemiaView official trial listing → -
Completed NCT NCT03332212
A Study That Looks at the Function of the Heart in Patients With Heart Failure Who Take Empagliflozin
Not yet reported Boehringer Ingelheim 72 participants Est. completion 2020-05-28 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT03351478
Efficacy and Safety of Sotagliflozin Versus Placebo and Empagliflozin in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking a DPP4 Inhibitor Alone or With Metformin
Not yet reported Lexicon Pharmaceuticals 770 participants Est. completion 2019-05-16 160 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03361098
DECREASE: Dapagliflozin Plus Exenatide on Central REgulation of Appetite in diabeteS typE 2
Not yet reported Amsterdam UMC, location VUmc 65 participants Est. completion 2020-03-25 1 site Added to GLP-1Type 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT03363464
Comparative Effectiveness of Empagliflozin in the US
Boehringer Ingelheim 230000 participants Est. completion 2026-07-09 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03366181
SGLT2i As Anti Arrhythmic Therapy to Prevent Sudden Cardiac Deaths.
University of Campania Luigi Vanvitelli 500 participants Est. completion 2017-11-26 1 siteHeart failureType 2 diabetes Other conditions: ICD, SGLT2iView official trial listing → -
Status unknown NCT NCT03398577
Effects of SGLT2 Inhibitor in Diabetic Patients With Coronary Artery Disease
Not yet reported Sheba Medical Center 61 participants Est. completion 2018-12-31 1 siteOther conditions: Coronary Disease With Diabetes MellitusView official trial listing → -
Terminated NCT NCT03419624
The Potential of Dapagliflozin Plus Exenatide in Obese Insulin-resistant Patients
Not yet reported Universitätsklinikum Hamburg-Eppendorf 13 participants Est. completion 2019-08-05 4 sitesType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT03422263
Performance Under SGLT-2-Inhibitors in Humans
Berner Klinik Montana 450 participants Est. completion 2020-09-30 1 siteType 2 diabetesView official trial listing → -
Withdrawn NCT NCT03423355
Dapagliflozin Effect on Erythropoiesis and Physical Fitness
Not yet reported University Hospital Tuebingen Est. completion 2023-12 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03426956
Glucose Absorption and Gut Hormone Secretion After Gastric Bypass
Not yet reported Hvidovre University Hospital 10 participants Est. completion 2019-05-01 1 siteOther conditions: OverweightView official trial listing → -
Completed NCT NCT03429543
Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM
Not yet reported Boehringer Ingelheim 175 participants Est. completion 2023-05-31 83 sites Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03433248
Renal Actions of Combined Empagliflozin and LINagliptin in Type 2 diabetES
Not yet reported M.H.H. Kramer 66 participants Est. completion 2022-09-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT03437330
Empagliflozin Effect on Glucose Toxicity
Not yet reported University Hospital Tuebingen Est. completion 2023-05-03 2 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03448406
This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Preserved Ejection Fraction (HFpEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms.
Not yet reported Boehringer Ingelheim 315 participants Est. completion 2019-10-09 108 sites Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT03448419
This Study Tests Empagliflozin in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF). The Study Looks at How Far Patients Can Walk in 6 Minutes and at Their Heart Failure Symptoms
Not yet reported Boehringer Ingelheim 312 participants Est. completion 2019-10-07 109 sites Stand-aloneHeart failureView official trial listing → -
Status unknown NCT NCT03458715
The Efficacy of Sodium-glucose Co-transporter 2 Inhibitor or Dipeptidyl Peptidase-4 Inhibitor in Type 2 Diabetes Patients With Premix Insulin
Not yet reported Mackay Memorial Hospital 120 participants Est. completion 2018-11-21 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03462069
Comparison of Pharmacodynamic Effects of Sotagliflozin and Empagliflozin in T2DM Patients With Mild to Moderate Hypertension
Not yet reported Sanofi 41 participants Est. completion 2019-04-18 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT03464045
Empa PASS on Urinary Tract Malignancies
Boehringer Ingelheim 344995 participants Est. completion 2024-03-11 3 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03473262
Empagliflozin-based Quadruple Combination vs Insulin Glarine-based Combination Therapy in Patients With Type 2 Diabetes
Chungbuk National University Hospital 200 participants Est. completion 2018-07-18Type 2 diabetesView official trial listing → -
Completed NCT NCT03485092
Studies of Empagliflozin and Its Cardiovascular, Renal and Metabolic Effects
Not yet reported NHS Greater Glasgow and Clyde 105 participants Est. completion 2020-03-28 1 siteHeart failure Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT03485222
Are the "Cardiac Benefits" of Empagliflozin Independent of Its Hypoglycemic Activity? (ATRU-4).
Not yet reported Icahn School of Medicine at Mount Sinai 84 participants Est. completion 2020-02-13 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT03492580
A Study for Comparison of Canagliflozin Versus Alternative Antihyperglycemic Treatments on Risk of Heart Failure Hospitalization and Amputation for Participants With Type 2 Diabetes Mellitus and the Subpopulation With Established Cardiovascular Disease
Janssen Research & Development, LLC 714582 participants Est. completion 2018-06-25 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Withdrawn NCT NCT03504566
Rotation for Optimal Targeting of Albuminuria and Treatment Evaluation (ROTATE-2)
Not yet reported Steno Diabetes Center Copenhagen Est. completion 2019-06-01 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT03510000
Alleviating Carbohydrate-Counting Burden in T1DM Using Artificial Pancreas and Empagliflozin
Not yet reported Samuel Lunenfeld Research Institute, Mount Sinai Hospital 30 participants Est. completion 2019-11-21 3 sites Stand-aloneOther conditions: Type1diabetesView official trial listing → -
Terminated NCT NCT03554200
EMPA Acute Heart Failure
Not yet reported RWTH Aachen University 19 participants Est. completion 2020-10-29 1 site Stand-aloneType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT03556033
Effect of Dapagliflozin on IAH in T1DM
Not yet reported Radboud University Medical Center 15 participants Est. completion 2019-12-20 1 siteOther conditions: Diabetes Mellitus, Type 1, Hypoglycemia, Hypoglycemia UnawarenessView official trial listing → -
Status unknown NCT NCT03557138
Study to Develop a Kinetic Model for FDG and Me4FDG in Kidneys of Type 2 Diabetic Patients
Not yet reported Medical University of Vienna 20 participants Est. completion 2020-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03560323
Ketones, Muscle Metabolism, and SGLT2 Inhibitors - Protocol 1
Not yet reported The University of Texas Health Science Center at San Antonio 41 participants Est. completion 2024-12-30 2 sitesHeart failureType 2 diabetesView official trial listing → -
Completed NCT NCT03560375
Mediterranean Diet, Circuit Resistance Training, Empagliflozin in Elderly With Type 2 Diabetes: a Study Protocol
Not yet reported Tel-Aviv Sourasky Medical Center 100 participants Est. completion 2021-02-10 1 site Stand-aloneType 2 diabetes Other conditions: Sarcopenia, Weight LossView official trial listing → -
Status unknown NCT NCT03565458
Gemigliptin, Dapagliflozin, Empagliflozin DDI Study
Not yet reported LG Chem 48 participants Est. completion 2018-12-22 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03573102
Effect of Sodium Glucose co Transporter 2 Inhibitor ( SGLT2) on Proteinuria in Diabetic Patients
Not yet reported Nahla H Tohami 60 participants Est. completion 2020-07 1 site Stand-aloneOther conditions: Diabetic NephropathiesView official trial listing → -
Status unknown NCT NCT03591991
Empagliflozin on Cardiac-renal Injury in Patients With STEAMI Patients After Primary PCI
Not yet reported Chinese PLA General Hospital 128 participants Est. completion 2019-09-01Other conditions: Reperfusion Injury, MyocardialView official trial listing → -
Completed NCT NCT03594110
EMPA-KIDNEY (The Study of Heart and Kidney Protection With Empagliflozin)
Not yet reported Boehringer Ingelheim 6609 participants Est. completion 2024-07-02 240 sites Stand-aloneChronic kidney diseaseView official trial listing → -
Status unknown NCT NCT03627039
Metformin And Cardiovascular Effectiveness vs SGLT2 (MACES)
Brigham and Women's Hospital 20000 participants Est. completion 2020-08-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03629054
This Study in Healthy People Tests Whether Taking a Low Strength of Empagliflozin, Linagliptin, and Metformin Together in 1 Pill is the Same as Taking Them in Separate Pills
Not yet reported Boehringer Ingelheim 30 participants Est. completion 2018-11-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT03631134
Effect of SGLT2 Inhibitor on Blood Glucose Profile in Type 2 Diabetic Patients Using Basal Insulin
Not yet reported Nanjing First Hospital, Nanjing Medical University 100 participants Est. completion 2019-01-30 Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT03639545
The Effects of Empagliflozin on Arterial Wall Characteristics
Not yet reported University Medical Centre Ljubljana 120 participants Est. completion 2019-01-30 1 siteOther conditions: Vascular Stiffness, Hypoglycemic Agents, Diabetes Complications, Diabetes Mellitus, Type 1View official trial listing → -
Withdrawn NCT NCT03640221
Ertugliflozin Versus Hydrochlorothiazide in Reducing Sympathetic Neural Overactivity in Patients With Hypertension and Recently-diagnosed Type 2 Diabetes.
Not yet reported Cedars-Sinai Medical Center Est. completion 2020-08-31 1 site Stand-aloneType 2 diabetes Other conditions: HypertensionView official trial listing → -
Terminated NCT NCT03642184
Efficacy and Safety of Empagliflozin in NODAT
Not yet reported RenJi Hospital 6 participants Est. completion 2019-01-31 1 siteOther conditions: New Onset Diabetes After Transplant, Kidney Transplant; ComplicationsView official trial listing → -
Completed NCT NCT03642717
Regulatory Request NIS in Korea
Boehringer Ingelheim 658 participants Est. completion 2020-04-30 20 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03646292
Antidiabetic Drugs for Steatotic Liver Disease
Not yet reported Yonsei University 51 participants Est. completion 2022-06-16 1 site Stand-aloneMASLDType 2 diabetes Other conditions: Digestive System Disease, Liver Diseases, Fatty Liver, Non-Alcoholic Fatty Liver Disease, Hypoglycemic Agents, Physiological Effects of Drugs, Sodium-Glucose Cotransporter 2 Inhibitors, Pioglitazone, Molecular Mechanisms of Pharmacological Action, Empagliflozin, ThiazolidinedionesView official trial listing → -
Completed NCT NCT03704818
Dapagliflozin Effects on Hypoglycemia
Not yet reported University of California, San Diego 22 participants Est. completion 2021-11-30 1 siteOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03713190
Effects of Empagliflozin on Endogenous Glucose Production in End Stage Renal Disease(ESRD).
Not yet reported University of Pisa 25 participants Est. completion 2020-03-15 1 siteOther conditions: End Stage Renal DiseaseView official trial listing → -
Completed NCT NCT03717207
Cardiac Autonomic Dysfunction in Diabetics Patients With Syncope
University of Campania Luigi Vanvitelli 242 participants Est. completion 2021-03-01 1 siteOther conditions: Syncope, VasovagalView official trial listing → -
Completed NCT NCT03723252
Dapagliflozin Efficacy and Action in NASH
Not yet reported Nanfang Hospital, Southern Medical University 154 participants Est. completion 2024-03-28 1 siteMASHView official trial listing → -
Completed NCT NCT03748810
Head-to-head Comparison of Empagliflozin and Dapagliflozin
Chungbuk National University Hospital 600 participants Est. completion 2022-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03753087
Effects of Empagliflozin on Exercise Capacity and Left Ventricular Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction and Type-2 Diabetes Mellitus
Not yet reported National Medical Research Center for Cardiology, Ministry of Health of Russian Federation 70 participants Est. completion 2022-01-10 1 site Stand-aloneHeart failureType 2 diabetesView official trial listing → -
Completed NCT NCT03764631
Post-authorization Safety Study in Type 2 Diabetic Patients in Saudi Arabia Treated With Empagliflozin to Assess the Incidence of Ketoacidosis, Severe Complications of Urinary Tract Infection, Volume Depletion, and Dehydration
Boehringer Ingelheim 1502 participants Est. completion 2021-01-11 21 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03766724
Pharmacokinetic and Pharmacodynamic Drug-Drug Interaction of Evogliptin and Empagliflozin or Dapagliflozin in Healthy Male Adults
Not yet reported Dong-A ST Co., Ltd. 42 participants Est. completion 2019-01-18 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03771781
Bioequivalence Study of Empagliflozin Tablet in Healthy Participants.
Not yet reported Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 48 participants Est. completion 2018-05-25 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03790787
Drug Interaction Study Between Dorzagliatin and Empagliflozin
Not yet reported Hua Medicine Limited 16 participants Est. completion 2020-03-15 1 site Stand-aloneOther conditions: PatientsView official trial listing → -
Completed NCT NCT03798054
Evaluation of Insulin Glargine/Lixisenatide Fixed Ratio Combination in Patients With Type 2 Diabetes Insufficiently Controlled With Oral Antidiabetic Drug(s)
Not yet reported Sanofi 878 participants Est. completion 2021-03-01 79 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Status unknown NCT NCT03804411
Prognostic Predictors of Response to Hypoglycemic Therapy
Not yet reported Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of Health 800 participants Est. completion 2020-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03807440
DIA_CENTRAL:T2D Treatment Pattern in Central Europe
Boehringer Ingelheim 4083 participants Est. completion 2021-08-31 177 sitesType 2 diabetesView official trial listing → -
Withdrawn NCT NCT03813316
Approaches To Therapy Escalation In T2D
Not yet reported LMC Diabetes & Endocrinology Ltd. Est. completion 2019-09-18 Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03817463
A Study to Observe the Effectiveness of Empagliflozin, Other SGLT-2 Inhibitors, or DPP-4 Inhibitors in Patients With Type 2 Diabetes
Boehringer Ingelheim 327624 participants Est. completion 2021-12-10 13 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03852901
Sodium-glucose Co Transporter 2 (sGLT2) Inhibitor and Endogenous Ketone Production
Not yet reported National Institute on Aging (NIA) 21 participants Est. completion 2021-12-13 1 site Stand-aloneOther conditions: Empaglifozin, Physiological Effects of Drugs, Hypoglycemic Agents, Sodium-Glucose Transporter 2 InhibitorsView official trial listing → -
Not yet recruiting NCT NCT03867487
SGLT2 Inhibitors as a Novel Treatment for Pediatric Non-Alcoholic Fatty Liver Disease
Not yet reported Justin Ryder 40 participants Est. completion 2028-02-01 1 site Stand-aloneMASLD Other conditions: Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT03871621
Left Ventricular Functional Changes of Uncontrolled Diabetes by Dapagliflozin Treatment Trial
Not yet reported Mackay Memorial Hospital 76 participants Est. completion 2022-08-31 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT03877406
Effect of Empagliflozin on Body Composition and Ketones
Not yet reported Seoul National University Bundang Hospital 200 participants Est. completion 2023-12-31 1 site Stand-aloneOther conditions: Diabetes Mellitus, Fat; Intolerance, PancreasView official trial listing → -
Active, not recruiting NCT NCT03878459
Dapagliflozin Plus Pioglitazone in T1DM
Not yet reported The University of Texas Health Science Center at San Antonio 120 participants Est. completion 2027-12-31 3 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03895229
The Effect of Morning Versus Evening Administration on The Pharmacokinetics and Pharmacodynamics of Empagliflozin
Not yet reported Ain Shams University 16 participants Est. completion 2018-10-26 1 site Stand-aloneOther conditions: Diabetes Mellitus, Pharmacokinetics, PharmacodynamicsView official trial listing → -
Active, not recruiting NCT NCT03899402
Triple Therapy in T1DM
Not yet reported, Not yet reported State University of New York at Buffalo 78 participants Est. completion 2026-06-30 1 site Added to GLP-1Other conditions: Type 1 Diabetes MellitusView official trial listing → -
Status unknown NCT NCT03912909
Effects of Sodium-glucose Co-transporter-2( SGLT-2 ) Inhibition on Sympathetic Nervous System Activity in Humans
Not yet reported Royal Perth Hospital 30 participants Est. completion 2024-12-30 1 siteMetabolic syndromeType 2 diabetes Other conditions: ObesityView official trial listing → -
Status unknown NCT NCT03917758
Antidiuretic Function Before and During Treatment With SGLT2 Inhibitors
Not yet reported University of Turin, Italy 30 participants Est. completion 2020-10-30 1 site Stand-aloneType 2 diabetes Other conditions: Arterial Hypertension, Body Weight ChangesView official trial listing → -
Completed NCT NCT03918148
Gliflozins and Cardiovascular Risk Factors in Type 2 Diabetes (GIOIA)
University of Campania Luigi Vanvitelli 1150 participants Est. completion 2023-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03921242
Comparative Effectiveness of Metformin for Type 2 Diabetes With Chronic Kidney Disease
Weill Medical College of Cornell University 4888 participants Est. completion 2023-08-01 2 sitesType 2 diabetes Other conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT03922750
A Research Study in People With Type 2 Diabetes to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine
Not yet reported Novo Nordisk A/S 154 participants Est. completion 2020-01-27 38 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT03932721
EXpanded Combination of Evolocumab Plus Empagliflozin on Diabetes: EXCEED-BHS3 Trial
Not yet reported University of Campinas, Brazil 110 participants Est. completion 2021-10-30 1 siteType 2 diabetes Other conditions: Dyslipidemia Associated With Type II Diabetes Mellitus, Hypertension ArterialView official trial listing → -
Terminated NCT NCT03933956
Metabolic Effects of the SGLT-2 Inhibitor Empagliflozin in Patients With Diabetic Nephropathy (MEDiaN)
Not yet reported Singapore General Hospital 2 participants Est. completion 2020-08-01 1 site Stand-aloneOther conditions: Diabetic NephropathiesView official trial listing → -
Completed NCT NCT03939624
Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors and Risk of Cardiovascular Events
Canadian Network for Observational Drug Effect Studies, CNODES 419734 participants Est. completion 2019-10-01 1 siteType 2 diabetesCardiovascular diseaseHeart failure Other conditions: Cardiovascular Death, All-Cause MortalityView official trial listing → -
Completed NCT NCT03951805
A Research Study to Compare Two Types of Insulin: Insulin 287 and Insulin Glargine in People With Type 2 Diabetes Who Have Not Used Insulin Before
Not yet reported Novo Nordisk A/S 205 participants Est. completion 2020-01-17 43 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT03968224
Effectiveness of Dapagliflozin for Weight Loss
Not yet reported, Not yet reported Centro Medico Nacional Siglo XXI IMSS 160 participants Est. completion 2024-07-31 1 sitePrediabetesType 2 diabetes Other conditions: Obesity, MorbidView official trial listing → -
Completed NCT NCT03970044
Effectiveness of Exenatide Plus Dapagliflozin on 24 Hour Glucose Variability Measured by CGM. A Proof of Concept.
Not yet reported Consano Clinical Research, LLC 67 participants Est. completion 2021-06-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03979352
Effect of SGLT2i in Conjunction With the Artificial Pancreas on Improving the Glycemia in T1DM in the Outpatient Setting
Not yet reported Samuel Lunenfeld Research Institute, Mount Sinai Hospital 28 participants Est. completion 2021-08-31 2 sitesOther conditions: Type1 Diabetes MellitusView official trial listing → -
Completed NCT NCT03982381
SGLT2 Inhibitor or Metformin as Standard Treatment of Early Stage Type 2 Diabetes
Not yet reported Uppsala University 2067 participants Est. completion 2026-01-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT03993132
A Study Using Medical Records of Danish People With Type 2 Diabetes Comparing Empagliflozin and Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) in the Occurrence of Serious Cardiovascular Outcomes
Boehringer Ingelheim 26774 participants Est. completion 2022-06-16 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04013581
Quadruple Oral Combination Therapy for Type 2 Diabetes Mellitus : Glycemic Control by Thiazolidinedione (TZD) or Sodium Glucose Co-transporter 2 (SGLT-2) Inhibitor as an add-on Therapy in Type 2 Diabetes Mellitus After Failure of an Oral Triple Antidiabetic Regimen
Not yet reported Yonsei University 121 participants Est. completion 2020-05-28 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04014192
Effects of SGLT2 Inhibitors on Islet Cell Function and Insulin Sensitivity in Patients of Type 2 Diabetes Mellitus
Not yet reported Peking Union Medical College Hospital 40 participants Est. completion 2020-07-31 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04017221
Safety of Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors Among Patients With Type 2 Diabetes
Canadian Network for Observational Drug Effect Studies, CNODES 1249636 participants Est. completion 2019-12-01 1 siteType 2 diabetes Other conditions: Urosepsis, Diabetic Ketoacidosis, Lower Extremity AmputationView official trial listing → -
Status unknown NCT NCT04018365
A Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance
Not yet reported Kobe University 8 participants Est. completion 2021-10-30 5 sites Stand-aloneOther conditions: Insulin Resistance - Type A, Insulin Resistance - Type B, Lipoatrophic Diabetes Mellitus, Insulin Resistance SyndromeView official trial listing → -
Status unknown NCT NCT04027023
Evaluation of the Impact of Intensive Short-Term Drug Therapy in Patients With Type 2 Diabetes Mellitus
Not yet reported Sciema UG 9 participants Est. completion 2021-05-31 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT04027530
Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study.
Not yet reported Amsterdam UMC, location VUmc 40 participants Est. completion 2023-01-09 1 siteType 2 diabetesChronic kidney disease Other conditions: Renal Hypoxia, Renoprotection, SGLT2 Inhibitor, ErtugliflozinView official trial listing → -
Completed NCT NCT04035031
Effects of Dapagliflozin on Hormonal Glucose Homeostasis in Type 1 Diabetes
Not yet reported Insel Gruppe AG, University Hospital Bern 13 participants Est. completion 2020-11-12 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Completed NCT NCT04043702
Combination of Topiramate and Empagliflozin is Considered a Good Option for the Treatment of Obesity
Ministry of Health and Population, Egypt 200 participants Est. completion 2019-07-29 1 siteOther conditions: ObesityView official trial listing → -
Completed NCT NCT04049045
Effects of Empagliflozin on Diuresis and Renal Function in Patients With Acute Decompensated Heart Failure
Not yet reported Christian Schulze 60 participants Est. completion 2021-06-29 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT04061200
Renal Effects of Treatment With Empagliflozin Alone or in Combination With Semaglutide in Patients With Type 2 Diabetes and Albuminuria
Not yet reported Steno Diabetes Center Copenhagen 80 participants Est. completion 2021-08-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04061473
Involvement of Dipeptidyl Peptidase-4 and Sodium-glucose Co-transporter-2 in Extrapancreatic Glucagon Secretion
Not yet reported University Hospital, Gentofte, Copenhagen 20 participants Est. completion 2019-08-20 1 siteOther conditions: Diabetes After Total PancreatectomyView official trial listing → -
Terminated NCT NCT04071626
Evaluating Metabolic Mechanisms of Ertugliflozin in Diabetes & Heart Failure
Not yet reported University Hospitals Cleveland Medical Center 9 participants Est. completion 2023-01-11 1 siteHeart failureType 2 diabetesView official trial listing → -
Completed NCT NCT04080518
Hepato-renal Regulation of Water Conservation in Heart Failure Patients With SGLT-2 Inhibitor Treatment
Not yet reported National Heart Centre Singapore 40 participants Est. completion 2021-11-10 1 siteHeart failure Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT04098575
A Study Based on Data From German Registries That Looks at Characteristics of People Who Take the Medicine Empagliflozin for Type 2 Diabetes
Boehringer Ingelheim 9571 participants Est. completion 2019-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04117763
Effect of Empagliflozin on Ventricular Repolarization.
Not yet reported University of Sao Paulo 90 participants Est. completion 2024-03-31 1 site Stand-aloneType 2 diabetes Other conditions: Coronary Heart Disease, Arrythmia, CardiacView official trial listing → -
Status unknown NCT NCT04127084
Effects of SGLT2 Inhibition Treatment on Different Levels of Albuminuria in Patients With Type 2 Diabetes
Not yet reported Zhongshan Hospital Xiamen University 70 participants Est. completion 2021-08 1 siteType 2 diabetesChronic kidney diseaseView official trial listing → -
Active, not recruiting NCT NCT04128995
Surgical or Medical Treatment
Not yet reported Children's Hospital Medical Center, Cincinnati 88 participants Est. completion 2026-12 3 sitesType 2 diabetes Other conditions: Pediatric Obesity, Bariatric Surgery CandidateView official trial listing → -
Status unknown NCT NCT04131582
Effect of Empagliflozin + Linagliptin + Metformin + Lifestyle in Patients With Prediabetes
Not yet reported Universidad de Guanajuato 34 participants Est. completion 2020-12-30 1 site Stand-aloneOther conditions: Prediabetic State, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT04138251
Safety, Efficacy Evaluation of Empagliflozin Administration for Neutropenia in Glycogenosis Type 1b and G6PC3 Deficiency
Not yet reported Cliniques universitaires Saint-Luc- Université Catholique de Louvain 5 participants Est. completion 2020-06-30 1 site Stand-aloneOther conditions: Glycogen Storage Disease Type I, Glucose 6 Phosphatase DeficiencyView official trial listing → -
Completed NCT NCT04143321
Antiischemic Effects of Empagliflozin in Diabetic Patients With Refractory Angina
Not yet reported Isfahan University of Medical Sciences 75 participants Est. completion 2019-05-23 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Withdrawn NCT NCT04143581
SGLT2 Inhibitors in Glomerular Hyperfiltration
Not yet reported Mario Negri Institute for Pharmacological Research Est. completion 2021-09-03 Stand-aloneChronic kidney disease Other conditions: ObesityView official trial listing → -
Status unknown NCT NCT04146155
Efficacy and Safety of Liraglutide in Type 2 Diabetes With Lower Extremity Arterial Disease
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 200 participants Est. completion 2021-12-31 1 site Added to GLP-1Type 2 diabetes Other conditions: Peripheral Vascular Disorder Due to Diabetes MellitusView official trial listing → -
Completed NCT NCT04149067
Study of Real-world Evidence With SGLT2i (Dapagliflozin) and DPP4i (Sitagliptin) in Type 2 Diabetes Patients in Spain
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla 1080 participants Est. completion 2019-03-15 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04151849
Effects of Diabetes Medications on Adrenal Function and Intestinal Microbiota
University of Tartu 23 participants Est. completion 2023-01-23 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04157751
A Study to Test the Effect of Empagliflozin in Patients Who Are in Hospital for Acute Heart Failure
Not yet reported Boehringer Ingelheim 530 participants Est. completion 2021-06-02 118 sites Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT04167761
Ertugliflozin: Cardioprotective Effects on Epicardial Fat
Not yet reported Stanford University 61 participants Est. completion 2023-12-31 1 siteCardiovascular diseaseType 2 diabetes Other conditions: Atherosclerosis, Insulin ResistanceView official trial listing → -
Completed NCT NCT04183868
Effects of empagliFlozin on myocardIal metabOlic Rate of glucosE Estimated Through 18FDG PET (FIORE Study)
Not yet reported University of Catanzaro 26 participants Est. completion 2021-10 1 site Stand-aloneType 2 diabetes Other conditions: Cardiovascular Risk FactorView official trial listing → -
Completed NCT NCT04184947
Cardiovascular Outcomes SGLT-2 Inhibitors Versus GLP-1 Receptor Agonists
University of Padova 10000 participants Est. completion 2020-02-29 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04195243
Dapagliflozin vs Empagliflozin on Flow Mediated Dilation in Type 2 Diabetes Mellitus
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 24 participants Est. completion 2020-12-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04196231
Durability of Combination of Insulin and GLP-1 Receptor Agonist or SGLT-2 Inhibitors Versus Basal Bolus Insulin Regimen in Type 2 Diabetes (BEYOND)
Not yet reported University of Campania Luigi Vanvitelli 258 participants Est. completion 2020-10-20 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04200586
The Effects of SGLTi on Diabetic Cardiomyopathy
Not yet reported The University of Hong Kong 30 participants Est. completion 2021-09-30 1 siteType 2 diabetesHeart failureView official trial listing → -
Completed NCT NCT04201496
SGLT2 Inhibitor Adjunctive Therapy to Closed Loop Control in Type 1 Diabetes Mellitus
Not yet reported Ananda Basu, MD 34 participants Est. completion 2021-09-07 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT04203914
Short Term Effect of Empagliflozin in Hypertension
Not yet reported Yaounde Central Hospital 15 participants Est. completion 2017-09-30 2 sites Stand-aloneOther conditions: HypertensionView official trial listing → -
Status unknown NCT NCT04203927
Effects of Empagliflozin on Cardiac Microvasculature and Insulin Sensitivity in Subjects With Type 2 Diabetes
Not yet reported University of Virginia 50 participants Est. completion 2023-11-30 1 siteType 2 diabetes Other conditions: Insulin SensitivityView official trial listing → -
Completed NCT NCT04213677
Dapagliflozin Efficacy and Action in PCOS
Not yet reported Nanfang Hospital, Southern Medical University 165 participants Est. completion 2022-11-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT04215445
Effect of SGLT2 Inhibition on OCT-A Parameters in Diabetic CKD
Not yet reported National University of Malaysia 90 participants Est. completion 2020-08 1 siteChronic kidney disease Other conditions: Diabetic Retinopathy, Diabetes MellitusView official trial listing → -
Completed NCT NCT04215536
Replication of the EMPAREG Diabetes Trial in Healthcare Claims
Brigham and Women's Hospital 103752 participants Est. completion 2021-02-18 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT04219124
The Effect of a SGLT2 Inhibitor on Glucose Flux, Lipolysis and Exercise in Type 2 Diabetes
Not yet reported University of Leicester 9 participants Est. completion 2020-01-08 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04221152
A Extension Study of Empagliflozin in Patients With Refractory Diabetes Mellitus With Insulin Resistance ( EMPIRE-02 )
Not yet reported Kobe University 8 participants Est. completion 2022-05-31 5 sites Stand-aloneOther conditions: Insulin Resistance - Type A, Insulin Resistance - Type B, Lipoatrophic Diabetes Mellitus, Insulin Resistance SyndromeView official trial listing → -
Completed NCT NCT04233801
A Study to Test How Well Empagliflozin Works in Chinese Patients With Type 2 Diabetes Who Already Take Insulin
Not yet reported Boehringer Ingelheim 219 participants Est. completion 2022-03-10 24 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04238702
Renohemodynamic Effects of Combined empagliflOzin and LosARtan
Not yet reported Amsterdam UMC, location VUmc 24 participants Est. completion 2021-09-27 1 site Stand-aloneType 2 diabetesChronic kidney diseaseView official trial listing → -
Status unknown NCT NCT04242758
Phthalates Exposure in Type 2 Diabetic Patients and Diuretic Therapy
Not yet reported University of Pisa 30 participants Est. completion 2020-04-01 1 site Stand-aloneOther conditions: Renal Function Disorder, Glucose Metabolism DisordersView official trial listing → -
Withdrawn NCT NCT04243850
REGROUP: Renohemodynamic Effects empaGliflozin in vaRiOUs Populations
Not yet reported Amsterdam UMC, location VUmc Est. completion 2022-03-01 Stand-aloneType 2 diabetesChronic kidney diseaseView official trial listing → -
Completed NCT NCT04249778
Dapagliflozin at Discharge on Hospital Heart Failure Readmission
Not yet reported Emory University 105 participants Est. completion 2022-03-03 3 sitesHeart failure Other conditions: DiabetesView official trial listing → -
Completed NCT NCT04295005
A Study Based on Data From German Sick Funds That Looks at the Costs of Treatment of Type-2 Diabetic Patients With Empagliflozin vs. DPP-4 Inhibitors vs. GLP-1 Receptor Agonists
Boehringer Ingelheim 24500 participants Est. completion 2021-09-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04298229
Efficacy and Safety of Dapagliflozin in Acute Heart Failure
Not yet reported Vanderbilt University Medical Center 240 participants Est. completion 2023-05-17 6 sites Stand-aloneHeart failureType 2 diabetesView official trial listing → -
Completed NCT NCT04304261
Effects of SGLT2i on the Cognitive Function in T2DM Patient (ESCDP)
Not yet reported Third Military Medical University 100 participants Est. completion 2024-04-30 1 siteType 2 diabetes Other conditions: Cognitive Functions ConfusionView official trial listing → -
Status unknown NCT NCT04304560
Value of SGLT2 Inhibitor (Dapagliflozin) as an Added Therapy in Diabetic Patients With Heart Failure With Reduced Ejection Fraction; Randomized Controlled Clinical Trial
Not yet reported Damanhour University 60 participants Est. completion 2021-04Heart failure Other conditions: Diabete Type 2, CardiomyopathiesView official trial listing → -
Active, not recruiting NCT NCT04333823
Adolescent Type 1 Diabetes Treatment With SGLT2i for hyperglycEMia & hyPerfilTration Trial
Not yet reported The Hospital for Sick Children 100 participants Est. completion 2024-05 3 sitesOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT04340908
Effects of SGLT2 Inhibitor on Type 2 Diabetic Patients Undergoing Cardiac Surgery
Not yet reported Hongchang Guo 500 participants Est. completion 2023-06-01 1 siteType 2 diabetes Other conditions: Cardiac SurgeryView official trial listing → -
Completed NCT NCT04342819
The Effect of empagliFlozin on Platelet Function profilEs in diabetiC patienTs - The EFFECT Study.
Not yet reported, Not yet reported The University of The West Indies 25 participants Est. completion 2021-12-31 1 site Stand-aloneOther conditions: Platelet Dysfunction Due to DrugsView official trial listing → -
Completed NCT NCT04345796
Pharmacological Reduction of Right Ventricular Enlargement
Not yet reported Asan Medical Center 56 participants Est. completion 2024-06-03 3 sitesOther conditions: Tricuspid Regurgitation, Right Ventricular DilatationView official trial listing → -
Completed NCT NCT04350593
Dapagliflozin in Respiratory Failure in Patients With COVID-19
Not yet reported Saint Luke's Health System 1250 participants Est. completion 2021-06-11 95 sitesOther conditions: COVID-19View official trial listing → -
Completed NCT NCT04375943
Clinical and Echocardiographic Management of Patients With Heart Failure and Diabetes: SCODIAC Follow up Study
Federico II University 406 participants Est. completion 2019-09-01 1 siteHeart failure Other conditions: DiabetesView official trial listing → -
Completed NCT NCT04385589
Dapagliflozin in Diabetic Patients (Type 2) With Decompensated Heart Failure
Not yet reported Assiut University 100 participants Est. completion 2020-12-20 1 siteHeart failureView official trial listing → -
Completed NCT NCT04393246
mulTi-Arm Therapeutic Study in Pre-ICu Patients Admitted With Covid-19 - Experimental Drugs and Mechanisms
Not yet reported, Not yet reported Cambridge University Hospitals NHS Foundation Trust 454 participants Est. completion 2022-06-08 1 siteOther conditions: COVID-19View official trial listing → -
Completed NCT NCT04400760
The Effect of Dapagliflozin on Platelet Function testinG Profiles in Diabetic PatiEnts.
Not yet reported, Not yet reported The University of The West Indies 40 participants Est. completion 2022-06-30 1 siteOther conditions: Platelet DysfunctionView official trial listing → -
Terminated NCT NCT04416269
Oral Anti Diabetic Agents in the Hospital
Not yet reported Emory University 85 participants Est. completion 2025-04-11 3 sites Added to GLP-1Other conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04419337
Pioglitazone and SGLT2 Inhibitors vs. DPP4 Inhibitors in Patients With Stroke
Not yet reported Chang Gung Memorial Hospital 200 participants Est. completion 2024-01-31 1 site Stand-aloneCardiovascular disease Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT04431141
Pharmacokinetic Drug Interaction Between Teneligliptin and Empagliflozin
Not yet reported Handok Inc. 32 participants Est. completion 2021-01-25 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04447911
Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia
Not yet reported University Hospital, Basel, Switzerland 113 participants Est. completion 2026-09-17 6 sites Stand-aloneOther conditions: Hyponatremia, SIADH, Liver Failure, Kidney FailureView official trial listing → -
Completed NCT NCT04450563
Low Dose Empagliflozin in Adults With Type 1 Diabetes on Closed Loop Insulin System
Not yet reported McGill University 25 participants Est. completion 2022-01-13 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT04461041
Empagliflozin and Cardiac Remodelling in People Without Diabetes
Not yet reported Unity Health Toronto 169 participants Est. completion 2022-07-31 4 sitesCardiovascular disease Other conditions: Left Ventricular HypertrophyView official trial listing → -
Completed NCT NCT04497792
Safety and Efficacy of Empagliflozin for Patients With Diabetes Mellitus and Planned Percutaneous Coronary Interventions
Not yet reported Research Institute for Complex Problems of Cardiovascular Diseases, Russia 40 participants Est. completion 2019-11 Stand-aloneCardiovascular disease Other conditions: Diabetes Mellitus, Percutaneous Coronary InterventionView official trial listing → -
Completed NCT NCT04505774
Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 ACUTE
Not yet reported Matthew Neal MD 3591 participants Est. completion 2024-01-26 101 sitesOther conditions: Covid19View official trial listing → -
Completed NCT NCT04509674
EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)
Not yet reported Boehringer Ingelheim 6522 participants Est. completion 2023-11-05 439 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT04520646
A Pilot Study of Empagliflozin in the Treatment of Acromegalic Cardiomyopathy
Not yet reported Huashan Hospital 10 participants Est. completion 2022-08-31 1 site Stand-aloneOther conditions: Acromegaly, CardiomyopathiesView official trial listing → -
Completed NCT NCT04523064
POST-CABGDM: Empagliflozin in Perioperative CABG
Not yet reported University of Sao Paulo General Hospital 155 participants Est. completion 2024-01-30 1 siteType 2 diabetesCardiovascular disease Other conditions: Coronary Artery Bypass Surgery, Acute Kidney InjuryView official trial listing → -
Completed NCT NCT04531462
A Study to Test How Well Empagliflozin Works in Japanese People With Type 2 Diabetes Who Are Older Than 65 Years
Not yet reported Boehringer Ingelheim 129 participants Est. completion 2022-08-26 18 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04534270
Efficacy and Safety of Dapagliflozin in Children With Proteinuria
Not yet reported Children's Hospital of Fudan University 23 participants Est. completion 2022-03-30 1 siteOther conditions: ProteinuriaView official trial listing → -
Status unknown NCT NCT04535960
Incretin and Treatment With Inhibition of Sodium-glucose Cotransporter-2 Combination Insights Into Mechanisms Implicated in Congestive Heart Failure: "NATRIURETIC" Trial
Not yet reported University Health Network, Toronto 36 participants Est. completion 2023-10 1 site Added to GLP-1Type 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT04541797
Stress Cardiac Magnetic Resonance of Asymptomatic Type 2 Diabetics with Cardiovascular High Risk to Measure Empagliflozin Impact on Myocardial Blood Flow (CATCH-EM)
Not yet reported The University of Hong Kong 160 participants Est. completion 2025-02-28 1 site Stand-aloneType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT04545411
Combination GRA and SGLT-2i Treatment in Type 1 Diabetes
Not yet reported, Not yet reported University of California, San Diego 12 participants Est. completion 2022-10-31 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Status unknown NCT NCT04583813
Empagliflozin and Atrial Fibrillation Treatment
Not yet reported Miulli General Hospital 400 participants Est. completion 2024-04 1 siteHeart failure Other conditions: Atrial Fibrillation, Obesity, Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04603508
Efficacy and Safety of Berlim 25/10 Association in the Treatment of Type II Diabetes Mellitus and Dyslipidemia
Not yet reported EMS 240 participants Est. completion 2025-08 Stand-aloneType 2 diabetes Other conditions: DyslipidemiaView official trial listing → -
Status unknown NCT NCT04621656
Sugar Challenge Study
January, Inc. 1022 participants Est. completion 2021-10 1 siteType 2 diabetesPrediabetes Other conditions: HealthyView official trial listing → -
Status unknown NCT NCT04626323
Randomized Study Comparing Metabolic Surgery With Intensive Medical Therapy to Treat Diabetic Kidney Disease
Not yet reported Hospital Alemão Oswaldo Cruz 60 participants Est. completion 2024-12 1 site Stand-aloneType 2 diabetes Other conditions: Kidney Disease, Chronic, Kidney InjuryView official trial listing → -
Completed NCT NCT04633005
Polypill Strategy for Heart Failure With Reduced Ejection Fraction
Not yet reported University of Texas Southwestern Medical Center 212 participants Est. completion 2025-10-31 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT04639414
Combined Active Treatment in Type 2 Diabetes With NASH
Not yet reported German Diabetes Center 192 participants Est. completion 2025-11-17 26 sites Added to GLP-1Type 2 diabetesMASHMASLDView official trial listing → -
Withdrawn NCT NCT04640493
SGLT2-Inhibitors for Sleep Apnea in Heart Failure
Not yet reported Columbia University Est. completion 2025-08 1 siteHeart failure Other conditions: Sleep Disordered BreathingView official trial listing → -
Completed NCT NCT04642261
Effect of Empagliflozin on Liver Fat in Non-diabetic Patients
Not yet reported The University of Hong Kong 98 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: Non-alcoholic Fatty Liver DiseaseView official trial listing → -
Status unknown NCT NCT04662866
Effects of Glucose Lowering Agents in South Asian Women With Impaired Glucose Tolerance or Impaired Fasting Glucose
Not yet reported Oslo University Hospital 64 participants Est. completion 2023-10 1 sitePrediabetes Other conditions: Insulin Sensitivity, Glucose Metabolism DisordersView official trial listing → -
Completed NCT NCT04665284
Safety And Efficacy Of Empagliflozin In Pakistani Muslim Population With Type Ii Diabetes Mellitus
Not yet reported Getz Pharma 244 participants Est. completion 2020-09-28 11 sites Stand-aloneOther conditions: Type II Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04667143
Dual Add-on Therapy in Type 2 Diabetes Poorly Controlled With Metformin Monotherapy
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 760 participants Est. completion 2022-10Other conditions: Diabetes Mellitus, Type IIView official trial listing → -
Completed NCT NCT04696185
Dapagliflozin After Transcatheter Aortic Valve Implantation
Not yet reported Spanish Society of Cardiology 1257 participants Est. completion 2024-12-30 40 sitesOther conditions: Aortic Stenosis, Transcatether Aortic Valve ImplantationView official trial listing → -
Withdrawn NCT NCT04697485
Polydiuretic Therapy for Heart Failure With Preserved Ejection Fraction and Diabetes Mellitus
Not yet reported Northwestern University Est. completion 2022-03-30 1 site Stand-aloneHeart failure Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT04700839
SGLT2 Inhibitors in Patients With PCOS
Not yet reported Shanghai 10th People's Hospital 68 participants Est. completion 2021-04-30 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT04702490
Study to Evaluate MET409 Alone or in Combination With Empagliflozin in Patients With Type 2 Diabetes and NASH
Not yet reported Metacrine, Inc. 120 participants Est. completion 2022-06 2 sites Stand-aloneMASHType 2 diabetesMASLD Other conditions: Diabetes Type 2, Diabetes, Fatty Liver, Fatty Liver, NonalcoholicView official trial listing → -
Completed NCT NCT04735042
SGLT-2 and DPP-4 Inhibition, Subclinical Inflammation of the Genito-urinary Tract and Risk of Infections.
University of Pisa 60 participants Est. completion 2022-04-07 1 siteType 2 diabetes Other conditions: Urinary Tract InfectionsView official trial listing → -
Withdrawn NCT NCT04764097
Dapagliflozin Effect on Cardiovascular Outcomes in Haemodialysis for End Stage Renal Disease
Not yet reported, Not yet reported Tan Tock Seng Hospital Est. completion 2026-06Cardiovascular disease Other conditions: End Stage Renal DiseaseView official trial listing → -
Completed NCT NCT04778787
Sodium-glucose Cotransporter Type 2 Inhibitors for Acute Cardiorenal Syndrome Prevention
Not yet reported I.M. Sechenov First Moscow State Medical University 370 participants Est. completion 2022-08-01 2 sitesHeart failureView official trial listing → -
Status unknown NCT NCT04780438
Dapagliflozin to Prevent Atrial Fibrillation Recurrence After Transcatheter Pulmonary Venous Isolation.
Not yet reported G.Gennimatas General Hospital 350 participants Est. completion 2023-12-01 2 sitesOther conditions: Atrial Fibrillation Recurrent, Pulmonary Venous Isolation, Catheter Ablation, Sodium-glucose Co-transporter 2 InhibitorsView official trial listing → -
Completed NCT NCT04791826
Electronic Alerts for Heart Failure Prevention in Diabetes
Not yet reported University of Texas Southwestern Medical Center 1524 participants Est. completion 2024-05-07 1 site Stand-aloneHeart failureType 2 diabetesView official trial listing → -
Status unknown NCT NCT04796428
GliflOzin in eLderly Diabetic patiENts: A praGmatic Intraclass Evaluation Trial
Not yet reported Center for Outcomes Research and Clinical Epidemiology, Italy 1167 participants Est. completion 2023-12-31Type 2 diabetesView official trial listing → -
Completed NCT NCT04818034
The Effect of Sodium-glucose Cotransporter (SGLT) 2 Inhibitors on Cystine Stone Formation: A Preliminary Study
Not yet reported University of California, San Francisco 10 participants Est. completion 2022-04-28 1 siteOther conditions: CystinuriaView official trial listing → -
Status unknown NCT NCT04853615
SGLT2 Inhibitors Prophylaxis Against Post-contrast Acute Kidney Injury in Diabetic Kidney Disease?
Fayoum University 800 participants Est. completion 2024-08-01Other conditions: SGLT2i Kideny Protection Against Contrast in Diabetic KidneyView official trial listing → -
Status unknown NCT NCT04860011
DAPAgliflozin Versus Thiazide Diuretic in Patients With Heart Failure and Diuretic RESISTance
Not yet reported NHS Greater Glasgow and Clyde 61 participants Est. completion 2023-04-03 2 sites Stand-aloneHeart failureView official trial listing → -
Status unknown NCT NCT04862858
Educational Intervention to Increase Select Guideline-recommended Cardioprotective Medications in Patients With Diabetes
Not yet reported Humana Inc. 4197 participants Est. completion 2022-08-16 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT04869800
Evaluate the Drug-drugs Interaction Between Lobeglitazone 0.5mg and Empagliflozin 25mg
Not yet reported Chong Kun Dang Pharmaceutical 32 participants Est. completion 2021-06-15 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04882358
Safety & Feasibility of DSR TherApy in Heart FAiluRe pAtients With Persistent Congestion
Not yet reported Sequana Medical N.V. 24 participants Est. completion 2024-12-31 2 sites Stand-aloneHeart failure Other conditions: Volume OverloadView official trial listing → -
Terminated NCT NCT04906213
CardioRenal Effects of SGLT2 Inhibition in Kidney Transplant Recipients
Not yet reported Duke University 20 participants Est. completion 2026-01-22 1 siteType 2 diabetes Other conditions: Kidney Transplant; ComplicationsView official trial listing → -
Completed NCT NCT04907214
SGLT2 Inhibitor Effects on Inflammation and Heart Disease in Obesity Pilot
Not yet reported, Not yet reported Vanderbilt University Medical Center 29 participants Est. completion 2023-12-08 1 site Stand-alonePrediabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT04910178
Follow-up of NAFLD Patients With MRI-PDFF
Not yet reported Asmaa Abdelfattah Elsayed 80 participants Est. completion 2021-12-30 1 site Stand-aloneMASLD Other conditions: Diabetes Type 2View official trial listing → -
Completed NCT NCT04911660
Impact of the SGLT2 Inhibitor Empagliflozin on Urinary Supersaturations in Kidney Stone Formers
Not yet reported Insel Gruppe AG, University Hospital Bern 50 participants Est. completion 2023-04-28 1 siteOther conditions: Kidney StoneView official trial listing → -
Withdrawn NCT NCT04917692
Empagliflozin in Adolescent Diabetes
Not yet reported Ohio State University Est. completion 2022-10 1 site Stand-aloneOther conditions: type1diabetesView official trial listing → -
Completed NCT NCT04918407
Effects of Empagliflozin in Reducing Oxidative Stress After Kidney Transplantation
Not yet reported Shahid Beheshti University of Medical Sciences 40 participants Est. completion 2025-08-05 2 sites Stand-aloneOther conditions: Kidney Transplant; ComplicationsView official trial listing → -
Completed NCT NCT04927858
A Study Using Swedish Registries to Find Out How Many People With Type 2 Diabetes Had Cardiovascular Disease and Started Treatment With Empagliflozin Between 2015 and 2017
Boehringer Ingelheim 460558 participants Est. completion 2018-11-15 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT04930627
Safety and Efficacy of Empagliflozin in GSD1b Patients With Neutropenia
Not yet reported Children's Memorial Health Institute, Poland 20 participants Est. completion 2025-03 1 site Stand-aloneOther conditions: Glucose 6 Phosphatase DeficiencyView official trial listing → -
Completed NCT NCT04937816
This Study Combines Data From 3 Other Studies Testing Empagliflozin in Patients With Diabetes or With Chronic Heart Failure. The Study Looks at the Numbers of Patients Who Had Lower Limb Amputations
Boehringer Ingelheim 16746 participants Est. completion 2021-07-13 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT04956263
A Comparison of Postprandial Glucose After a MMTT, and the Metabolic Effects of Insulin Withdrawal in a Crossover Study in Subjects With Type 1 Diabetes
Not yet reported Youngene Therapeutics Inc., Ltd. 19 participants Est. completion 2022-07-19 1 siteOther conditions: Diabetes, Diabetes Mellitus, Type 1, Type1diabetes, Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04961931
Effect of Empagliflozin on Urinary Excretion of Adenosine and Osteocyte Function in Patients With Chronic Kidney Disease
Not yet reported Medical University of Lodz 45 participants Est. completion 2021-08-31 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT04965935
Efficacy, Mechanisms and Safety of SGLT2 Inhibitors in Kidney Transplant Recipients
Not yet reported University Health Network, Toronto 52 participants Est. completion 2024-08-30 1 siteType 2 diabetes Other conditions: Kidney Transplant Recipients, Post-transplant Diabetes MellitusView official trial listing → -
Withdrawn NCT NCT04970108
Efficacy and Safety of Egito Association in the Treatment of Type II Diabetes Mellitus and Hypertension
Not yet reported EMS Est. completion 2025-05 Stand-aloneOther conditions: Hypertension Associated, Type II Diabetes MellitusView official trial listing → -
Status unknown NCT NCT04976283
Effect of Oral Anti-diabetic Medication on Liver Fat in Subjects With Type II Diabetes and Non-alcoholic Fatty Liver
Not yet reported Getz Pharma 123 participants Est. completion 2023-11-15 1 siteType 2 diabetesMASHMASLDView official trial listing → -
Status unknown NCT NCT04986735
Prospective Cohort Study of Children With GSD1b Receiving Empagliflozin
Hong Kong Children's Hospital 11 participants Est. completion 2023-12-31 1 siteOther conditions: Glycogen Storage Disease Type IBView official trial listing → -
Completed NCT NCT05013112
Ameliorating Metabolic Profiling After Kidney Transplantation (AMPKT)
Not yet reported West China Hospital 105 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Kidney Transplantation, Metabolic Disorder, Metformin, EmpagliflozinView official trial listing → -
Completed NCT NCT05013502
Empagliflozin in Diuretic Refractory Ascites
Not yet reported Stanford University 14 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: Liver Cirrhosis, Cirrhosis, Ascites, Ascites Hepatic, Sodium-Glucose Transporter 2 InhibitorsView official trial listing → -
Status unknown NCT NCT05014594
Sodium-glucose Linked Transporter 2 (SGLT-2) Inhibitors in Recurrent Ascites: a Pilot RCT
Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 44 participants Est. completion 2022-05-19 1 siteOther conditions: Cirrhosis, Ascites HepaticView official trial listing → -
Status unknown NCT NCT05020704
EMpagliflozin to PREvent worSening of Left Ventricular Volumes and Systolic Function After Myocardial Infarction
Not yet reported NHS Greater Glasgow and Clyde 100 participants Est. completion 2024-06-12 3 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT05021419
Efficacy of a Streamlined Heart Failure Optimization Protocol
Not yet reported The Queen Elizabeth Hospital King's Lynn NHS Foundation Trust 60 participants Est. completion 2024-01-07 1 site Stand-aloneHeart failureView official trial listing → -
Enrolling by invitation NCT NCT05029115
The Effect of SGLT-2 Inhibitor in Patient With Atrial Fibrillation and Diabetes Mellitus
Ewha Womans University Mokdong Hospital 716 participants Est. completion 2026-12 1 siteType 2 diabetes Other conditions: SGLT-2 Inhibitor, Atrial FibrillationView official trial listing → -
Status unknown NCT NCT05032001
ORAL ANTIDIABETICS EFFECT ON VISCERAL FAT
Not yet reported Metabolic Research Unit 30 participants Est. completion 2022-08-01 1 siteType 2 diabetes Other conditions: Abdominal ObesityView official trial listing → -
Completed NCT NCT05033054
Effect of SGLT2i on Cardiovascular Biomarkers in Patients With Type 2 Diabetes and CKD Stage 3b-4
University of Texas Southwestern Medical Center 33 participants Est. completion 2025-02-01 1 siteOther conditions: Kidney Disease, Chronic, DiabetesView official trial listing → -
Terminated NCT NCT05036317
Empagliflozin for the Treatment of Postprandial Hypoglycemia
Not yet reported University Hospital, Basel, Switzerland 40 participants Est. completion 2024-08-05 3 sites Stand-aloneOther conditions: Postprandial HypoglycemiaView official trial listing → -
Completed NCT NCT05036421
Effect of Glucuronosyltransferase (UGT) Genetic Variation on Pharmacokinetics of Empagliflozin
Not yet reported Ain Shams University 18 participants Est. completion 2022-05-20 1 site Stand-aloneOther conditions: Pharmacogenomic, PharmacokineticsView official trial listing → -
Status unknown NCT NCT05037695
SGLT-2 Inhibitors in Prevention of Post-procedural Renal and Cardiovascular Complications aFter PCI Among Patients With Diabetes Mellitus and Coronary Artery Disease: a Prospective, Randomized, Pilot Study (SAFE-PCI)
Not yet reported University of Sao Paulo General Hospital 40 participants Est. completion 2022-12 1 site Stand-aloneType 2 diabetesCardiovascular disease Other conditions: Acute Kidney InjuryView official trial listing → -
Active, not recruiting NCT NCT05040087
Changing the Natural History of Type 2 Diabetes ("CHANGE" Study)
Not yet reported Foundation for Atlanta Veterans Education and Research, Inc. 127 participants Est. completion 2028-06-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05041673
Anti-diabetic Drugs and Fatty Liver Management
Not yet reported Alexandria University 120 participants Est. completion 2022-09-30 1 site Stand-aloneType 2 diabetes Other conditions: Fatty Liver, NonalcoholicView official trial listing → -
Completed NCT NCT05042973
The Metabolic Effects of Empagliflozin in Patients With High Risk of Heart Failure
Not yet reported Jacob Moller 165 participants Est. completion 2025-01-23 2 sitesHeart failure Other conditions: ObesityView official trial listing → -
Status unknown NCT NCT05047471
To Improve the Ability of Early Screening and Diagnosis in Patients With Diabetic Nephropathy
Yiming Mu 10000 participants Est. completion 2023-06 50 sitesChronic kidney diseaseView official trial listing → -
Completed NCT NCT05057819
Investigating the Impact of the SGLT2 Inhibitor Empagliflozin on Postprandial Hypoglycaemia After Gastric Bypass
Not yet reported Insel Gruppe AG, University Hospital Bern 22 participants Est. completion 2022-08-11 1 site Stand-aloneOther conditions: Dumping Syndrome, Hypoglycemia, ReactiveView official trial listing → -
Withdrawn NCT NCT05058417
Assessment of Empagliflozin as Adjuvant Therapy in Patients With Ulcerative Colitis
Not yet reported Sadat City University Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Ulcerative ColitisView official trial listing → -
Withdrawn NCT NCT05058859
Long Term Clinical Efficacy of Sodium-glucose Cotransporter-2 (SGLT-2) Inhibitor in Cystinurics
Not yet reported University of California, San Francisco Est. completion 2025-11-01 1 siteOther conditions: CystinuriaView official trial listing → -
Completed NCT NCT05073692
Comparison of Type 2 Diabetes Pharmacotherapy Regimens
Kaiser Permanente 241981 participants Est. completion 2025-03-12 6 sitesType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT05078879
Empagliflozin as a Treatment for Severe Congenital Neutropenia Due to G6PC3 Deficiency
Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 4 participants Est. completion 2025-05-21 1 site Stand-aloneOther conditions: Crohn's Disease, Glycogen Metabolism, Inflammatory Bowel Disease (IBD)View official trial listing → -
Completed NCT NCT05081219
SNIFF - Combo INI+EMPA Trial
Not yet reported Wake Forest University Health Sciences 47 participants Est. completion 2024-09-17 1 site Stand-aloneOther conditions: Mild Cognitive Impairment, Cognitive Impairment, Alzheimer DiseaseView official trial listing → -
Completed NCT NCT05083949
A Study in Healthy Humans to Assess the Relative Bioavailability of One Fixed-dose Combination Tablet Empagliflozin/Metformin Versus Jardiance® Tablet and Glifage® Tablet Administered Together
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2021-09-09 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05084235
The Cardiac Effects of Empagliflozin in Patients With High Risk of Heart Failure
Not yet reported Jacob Moller 191 participants Est. completion 2025-01-16 2 sitesHeart failure Other conditions: ObesityView official trial listing → -
Active, not recruiting NCT NCT05090358
Preventing High Blood Sugar in People Being Treated for Metastatic Breast Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 15 participants Est. completion 2027-10-08 9 sites Stand-aloneOther conditions: Breast Cancer, Breast Cancer Stage IV, Metastatic Breast CancerView official trial listing → -
Withdrawn NCT NCT05102071
Clinical Outcomes and Healthcare Cost and Resource Utilization (HCRU) in Patients With Type 2 Diabetes and Cardiovascular Disease on 2nd Line Empagliflozin Versus 2nd Line Sulfonylureas
Boehringer Ingelheim Est. completion 2022-06-15 1 siteType 2 diabetesCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT05103306
Empagliflozin-based Quadruple Therapy vs Basal Insulin-based Therapy
Chungbuk National University Hospital 300 participants Est. completion 2022-12Type 2 diabetesView official trial listing → -
Status unknown NCT NCT05105698
Food-effect Bioavailability of Gemigliptin and Dapagliflozin 50/10 mg
Not yet reported LG Chem 28 participants Est. completion 2022-09-30Other conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT05109949
Acute Effect of Empagliflozin vs Dapagliflozin Over Pulse Wave Velocity in Type Two Diabetes
Not yet reported Centro Universitario de Ciencias de la Salud, Mexico 72 participants Est. completion 2022-08-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Terminated NCT NCT05129722
Polydiuretic Therapy for HFpEF, a Randomised Controlled Trial
Not yet reported The George Institute 3 participants Est. completion 2024-05-01 2 sites Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT05130463
Esgliteo Post Marketing Surveillance (PMS) in Korean Patients With Type 2 Diabetes Mellitus
Boehringer Ingelheim 1053 participants Est. completion 2024-07-08 30 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05132023
Bioequivalence Study of Empagliflozin & Metformin HCL From Empagliform 12.5/1000 mg F.C.T (Hikma Pharma, Egypt) and Synjardy 12.5/1000 mg F.C.T (Boehringer Ingelheim International GmbH, Germany)
Not yet reported Genuine Research Center, Egypt 26 participants Est. completion 2019-05-15 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05139472
Impact of Empagliflozin on Functional Capacity in Heart Failure with Preserved Ejection Fraction
Not yet reported University of Texas Southwestern Medical Center 8 participants Est. completion 2024-02-19 2 sites Stand-aloneHeart failure Other conditions: Diabetes MellitusView official trial listing → -
Terminated NCT NCT05139914
Assessment of Dapagliflozin on Vascular Health in Patients With Type 2 Diabetes
Not yet reported Boston University 4 participants Est. completion 2025-02-04 1 siteType 2 diabetes Other conditions: Endothelial DysfunctionView official trial listing → -
Status unknown NCT NCT05140694
Effect of Empagliflozin and Dulaglutide on MAFLD in Patients With T2D
Not yet reported Seoul National University Bundang Hospital 135 participants Est. completion 2025-12-31 MixedType 2 diabetes Other conditions: Metabolic-associated Fatty Liver DiseaseView official trial listing → -
Withdrawn NCT NCT05144360
Efficacy and Safety of Atenas Association in the Treatment of Type II Diabetes Mellitus and Hypertension
Not yet reported EMS Est. completion 2024-11 Stand-aloneOther conditions: Hypertension Associated, Type II Diabetes MellitusView official trial listing → -
Active, not recruiting NCT NCT05147090
Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B Patients
Not yet reported The University of Hong Kong 106 participants Est. completion 2027-12-31 1 siteMASLD Other conditions: Chronic Hepatitis b, Cirrhosis, Fibrosis, Liver, Empagliflozin, SGLT2 InhibitorsView official trial listing → -
Completed NCT NCT05152940
ERTU-SODIUM: Study on the Effects of Ertugliflozin on Sodium Storage, Interstitial Volume, and Plasma Volume in HFrEF
Not yet reported Icahn School of Medicine at Mount Sinai 28 participants Est. completion 2023-10-27 1 siteHeart failure Other conditions: CongestionView official trial listing → -
Status unknown NCT NCT05161429
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
Brigham and Women's Hospital 550000 participants Est. completion 2024-06-30 5 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05162014
To Assess the Risk of Acute Pancreatitis in Patients With Type 2 Diabetes Mellitus Treated With Empagliflozin
Boehringer Ingelheim 494679 participants Est. completion 2022-09-12 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05162690
Efficacy of Dapagliflozin in Diabetes Associated Peripheral Neuropathy
Not yet reported, Not yet reported Post Graduate Institute of Medical Education and Research, Chandigarh 40 participants Est. completion 2023-12-31 1 siteOther conditions: Diabetic Peripheral NeuropathyView official trial listing → -
Completed NCT NCT05164523
The Effect of SGLT2 Inhibitors on Heart Rate Variability and BDNF Levels in Patients With Type 2 Diabetes
Goztepe Training and Research Hospital 64 participants Est. completion 2022-12-30 1 siteType 2 diabetes Other conditions: Heart Rate VariabilityView official trial listing → -
Withdrawn NCT NCT05174507
Empagliflozin and Anakinra for the Treatment of Postprandial Hypoglycemia in Patients With Prediabetes
Not yet reported University Hospital, Basel, Switzerland Est. completion 2026-05-01Other conditions: Postprandial HypoglycemiaView official trial listing → -
Active, not recruiting NCT NCT05182658
Empagliflozin in Hypertrophic Cardiomyopathy
Not yet reported National Institute of Cardiology, Warsaw, Poland 250 participants Est. completion 2026-11-30 2 sitesHeart failure Other conditions: Hypertrophic CardiomyopathyView official trial listing → -
Completed NCT NCT05182840
A Study to Test Whether Different Doses of BI 690517 Alone or in Combination With Empagliflozin Improve Kidney Function in People With Chronic Kidney Disease
Not yet reported Boehringer Ingelheim 714 participants Est. completion 2023-07-10 203 sites Stand-aloneOther conditions: Kidney Disease, ChronicView official trial listing → -
Status unknown NCT NCT05200793
Efficacy of Empagliflozin or Linagliptin as an Alternative to Metformin for Treatment of Polycystic Ovary Syndrome
Not yet reported Alexandria University 75 participants Est. completion 2022-09-01 1 siteOther conditions: Polycystic Ovary Syndrome (PCOS)View official trial listing → -
Completed NCT NCT05210517
SGLT2 Inhibition: Uric Acid Excretion Study
Not yet reported Amsterdam UMC, location VUmc 10 participants Est. completion 2021-09-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT05214573
Second-line Therapies for Patients With Type 2 Diabetes and Moderate Cardiovascular Disease Risk
Mayo Clinic 386301 participants Est. completion 2025-07-22 1 siteType 2 diabetes Other conditions: Cardiac DiseaseView official trial listing → -
Active, not recruiting NCT NCT05220917
Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study
Brigham and Women's Hospital 781430 participants Est. completion 2027-09-30 1 siteType 2 diabetes Other conditions: Cardiovascular Events, Renal DiseaseView official trial listing → -
Status unknown NCT NCT05225077
Short-term Use of Dapagliflozin to Protect Kidney Function in CKD Patients
Not yet reported Dong-A University 600 participants Est. completion 2023-12-31 1 siteOther conditions: Renal Insufficiency, Chronic, Cardiac Catheterization, Percutaneous Coronary InterventionView official trial listing → -
Completed NCT NCT05229796
Pharmacokinetics and Bioequivalence of Two Empagliflozin, With Evaluation in Healthy Jordanian Subjects Under Fasting and Fed Conditions
Not yet reported Mutah University 26 participants Est. completion 2021-12-12 1 siteOther conditions: Pharmacokinetic ParametersView official trial listing → -
Completed NCT NCT05232071
Placebo-controlled, Proof-of-concept Study to Evaluate the Safety and Efficacy of Lanifibranor Alone and in Combination With SGLT2 Inhibitor EmpaGliflozin in patiEnts With NASH and Type 2 Diabetes Mellitus
Not yet reported Inventiva Pharma 39 participants Est. completion 2024-06-04 42 sites Stand-aloneMASHType 2 diabetesView official trial listing → -
Completed NCT NCT05233163
SGLT2 Inhibitors in Transthyretin Amyloid Cardiomyopathy
Not yet reported Columbia University 15 participants Est. completion 2023-05-01 1 site Stand-aloneOther conditions: Transthyretin Amyloid CardiomyopathyView official trial listing → -
Completed NCT NCT05236673
Jardiance® Post Marketing Surveillance (PMS) in Korean Patients With Chronic Heart Failure
Boehringer Ingelheim 676 participants Est. completion 2025-04-30 21 sitesHeart failureView official trial listing → -
Status unknown NCT NCT05241431
Effect of Dapagliflozin on Myocardial and Renal Function Following Aortic Valve Stenosis Intervention
Not yet reported, Not yet reported University of Aarhus 106 participants Est. completion 2024-04-01 1 siteOther conditions: Aortic Stenosis, Left Ventricle HypertrophiedView official trial listing → -
Status unknown NCT NCT05252624
Henagliflozin in Patients With Atrial Fibrillation
Not yet reported Beijing Anzhen Hospital 100 participants Est. completion 2023-09-30 1 siteOther conditions: Atrial FibrillationView official trial listing → -
Completed NCT NCT05254002
A Study to Learn How Well the Treatment Combination of Finerenone and Empagliflozin Works and How Safe it is Compared to Each Treatment Alone in Adult Participants With Long-term Kidney Disease (Chronic Kidney Disease) and Type 2 Diabetes
Not yet reported Bayer 1664 participants Est. completion 2025-03-17 173 sites Stand-aloneType 2 diabetesChronic kidney diseaseView official trial listing → -
Completed NCT NCT05254626
Efficacy and Safety of Dapagliflozin in Patients with Non-alcoholic Steatohepatitis
Not yet reported Cairo University 100 participants Est. completion 2024-07-23 1 siteOther conditions: Non-alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT05262764
Post Marketing Surveillance (PMS) of JARDIANCE in Chronic Heart Failure (CHF)
Boehringer Ingelheim 1200 participants Est. completion 2024-06-28 1 siteHeart failureView official trial listing → -
Completed NCT NCT05266404
Phase 1 Bioequivalence Study of Dapagliflozin/Sitagliptin FDC vs Loose Combination of Single Components
Not yet reported AstraZeneca 46 participants Est. completion 2022-05-31 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05271162
Empagliflozin in the Prevention of Cardiotoxicity in Cancer Patients Undergoing Chemotherapy Based on Anthracyclines
Not yet reported Maria Sklodowska-Curie National Research Institute of Oncology 220 participants Est. completion 2028-02-24 2 sitesOther conditions: CardiotoxicityView official trial listing → -
Active, not recruiting NCT NCT05275608
Effects of VLCKD in Metabolic Syndrome
Not yet reported Azienda Ospedaliero Universitaria Maggiore della Carita 40 participants Est. completion 2026-12 1 siteType 2 diabetesMetabolic syndrome Other conditions: Non-alcoholic Fatty Liver Disease, ObesityView official trial listing → -
Completed NCT NCT05278962
HF Patients With LVADs Being Treated With SGLT2i
Not yet reported University of Chicago 32 participants Est. completion 2025-08-31 1 siteHeart failureView official trial listing → -
Terminated NCT NCT05282121
A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)
Not yet reported Boehringer Ingelheim 90 participants Est. completion 2024-06-07 31 sites Stand-aloneOther conditions: Liver Diseases, Hypertension, PortalView official trial listing → -
Completed NCT NCT05283057
Empagliflozin in Patients With Glomerulonephritis
Not yet reported Kasr El Aini Hospital 50 participants Est. completion 2021-09-30 1 siteOther conditions: Glomerulonephritis, ProteinuriaView official trial listing → -
Completed NCT NCT05284344
The Impact of Glucotoxicity on Gastric Emptying in Chinese Patients With Newly Diagnosed Type 2 Diabetes
University of Adelaide 78 participants Est. completion 2023-12-31 1 siteType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05295368
Strategies for Kidney Outcomes Prevention and Evaluation - The SKOPE Study
Not yet reported Duke-NUS Graduate Medical School 724 participants Est. completion 2027-12 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT05305495
Empagliflozin in Acute Heart Failure
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 25 participants Est. completion 2026-03-10 1 site Stand-aloneHeart failureChronic kidney diseaseView official trial listing → -
Completed NCT NCT05309785
Safety and Efficacy of Canagliflozin in Advanced CKD
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 34 participants Est. completion 2026-07-01 1 siteChronic kidney disease Other conditions: ESRDView official trial listing → -
Status unknown NCT NCT05310916
Effect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients
Not yet reported Nidae Alaa 60 participants Est. completion 2023-11 1 siteOther conditions: Diabetic RetinopathyView official trial listing → -
Completed NCT NCT05313529
LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 396 participants Est. completion 2026-07-01 5 sites Stand-aloneType 2 diabetes Other conditions: Mild Cognitive ImpairmentView official trial listing → -
Status unknown NCT NCT05314725
Treatment With SGLT-2 Inhibitor for Postoperative Hyperglycemia in Acute Abdominal Surgery - a Randomized Trial
Not yet reported Zealand University Hospital 24 participants Est. completion 2023-06-01 Stand-aloneOther conditions: Postoperative Hyperglycemia, Stress HyperglycemiaView official trial listing → -
Active, not recruiting NCT NCT05330221
Project 2: ACHIEVE- HF
Not yet reported Henry Ford Health System 364 participants Est. completion 2027-06-30 1 site Stand-aloneHeart failure Other conditions: HypertensionView official trial listing → -
Status unknown NCT NCT05333159
The Efficacy of SGLT-2 Inhibitor in Patients With CAD and DM Undergoing PCI.
Beijing Anzhen Hospital 1424 participants Est. completion 2024-12-30 1 siteCardiovascular disease Other conditions: Diabete MellitusView official trial listing → -
Completed NCT NCT05335629
Evaluation of the Effect of SGLT-2 Inhibitors on Cardiac Remodeling in Post Myocardial Infarction Patients
Not yet reported Ain Shams University 54 participants Est. completion 2023-10-01 1 siteCardiovascular diseaseType 2 diabetes Other conditions: Myocardial Remodeling, VentricularView official trial listing → -
Terminated NCT NCT05341388
The Effect of SGLT2 Inhibitors on Cognitive Functions and BDNF Levels in Patients With Type 2 Diabetes
Goztepe Training and Research Hospital 25 participants Est. completion 2021-11-30 1 siteType 2 diabetes Other conditions: Cognitive ImpairmentView official trial listing → -
Completed NCT NCT05344963
Deformation Imaging by Strain in Chronic Heart Failure Over Gliflozins: an Echocardiographic Register on Sodium-GLucose coTransporter-2 Inhibitors
Matteo Cameli 503 participants Est. completion 2024-06-01 1 siteHeart failure Other conditions: Sodium-GLucose coTransporter-2 InhibitorsView official trial listing → -
Terminated NCT NCT05346653
The Hemodynamic Effects of SGLT2i in Acute Decompensated Heart Failure
Not yet reported University of Chicago 1 participants Est. completion 2023-05-23 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT05347459
Cognitive Protective Effect of Newer Antidiabetic Drugs
Alexandria University 100 participants Est. completion 2023-12 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05350202
Emp-Activity: Empagliflozin Functional Capacity
Boehringer Ingelheim 3431 participants Est. completion 2024-07-25 350 sitesHeart failureView official trial listing → -
Completed NCT NCT05359341
Which is Better to Start With DPP-4 Inhibitors or SGLT-2 Inhibitors in Egyptian Diabetic Patients?
Not yet reported Sadat City University 175 participants Est. completion 2022-01-10 1 siteOther conditions: Diabete Type 2View official trial listing → -
Completed NCT NCT05359432
Comparison of Empaglifozin and Vildagliptin in Type 2 Diabetes Mellitus
Not yet reported Getz Pharma 120 participants Est. completion 2021-08-18 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05360615
The Effects of Empagliflozin on Renal Outcomes in Post Severe Acute Kidney Injury Survivors
Not yet reported Chulalongkorn University 147 participants Est. completion 2027-07-01 1 site Stand-aloneOther conditions: Empagliflozin in Post AKI Stage 2-3View official trial listing → -
Completed NCT NCT05364190
Canagliflozin in Patients With Acute Decompansted Heart Failure
Not yet reported October 6 University 142 participants Est. completion 2024-03-01 1 siteHeart failure Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT05367063
Canagliflozin and Myocardial Fibrosis
Not yet reported Shanghai Zhongshan Hospital 45 participants Est. completion 2025-03-20 1 siteType 2 diabetes Other conditions: Cardiovascular RiskView official trial listing → -
Status unknown NCT NCT05373004
Comparison Between the Efficacy of SGLT2 Inhibitor Therapy Versus ACE Inhibitor in the Treatment of Diabetic Kidney Disease
Not yet reported, Not yet reported Omar Tarek Elfarargi 212 participants Est. completion 2024-05 Stand-aloneChronic kidney diseaseView official trial listing → -
Completed NCT NCT05373680
Efficacy and Safety of Metformin Versus Empagliflozin on Chronic Kidney Disease Progression
Not yet reported, Not yet reported Tanta University 118 participants Est. completion 2024-04-01 2 sites Stand-aloneOther conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT05390307
Obesity Treatment to Improve Diabetes
Not yet reported Dasman Diabetes Institute 60 participants Est. completion 2024-01-01 1 site MixedOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT05402579
Diabetic Ketoacidosis From New SGLT2i: Can Genomics Estimate Risk
Mount Sinai Hospital, Canada 63 participants Est. completion 2025-01-20 2 sitesOther conditions: Diabetes Type 2, DKA, Diabetic KetoacidosisView official trial listing → -
Status unknown NCT NCT05408936
SGLT2 Inhibitors and Effects on Hematopoiesis, Inflammation and Metabolic Markers
University of Patras 80 participants Est. completion 2024-06-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05413369
iGlarLixi vs IDegAsp in Chinese Participants After OAD(s)
Not yet reported Sanofi 582 participants Est. completion 2023-10-20 60 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Completed NCT NCT05417646
Impact of SGLT2 on Glucosuria in HNF1A-MODY
Not yet reported Steno Diabetes Center Copenhagen 21 participants Est. completion 2023-06-14 1 siteType 2 diabetes Other conditions: Maturity-Onset Diabetes of the Young, Type 3View official trial listing → -
Status unknown NCT NCT05417880
Vitamin D, K2 Plus Empagliflozin Combination in Type Two Diabetes Mellitus
Not yet reported Scotmann Pharmaceuticals 340 participants Est. completion 2023-06 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT05419583
Targeting Investigation and Treatment in Patients With Type 2 Myocardial Infarction
Not yet reported University of Edinburgh 60 participants Est. completion 2024-06-30 2 sitesCardiovascular diseaseView official trial listing → -
Completed NCT NCT05426525
Use of Empagliflozin to Treat Prediabetes
Not yet reported Oregon State University 60 participants Est. completion 2026-08-20 1 site Stand-alonePrediabetes Other conditions: Prediabetic State, Overweight and ObesityView official trial listing → -
Completed NCT NCT05430243
Empagliflozin as a Novel Therapy in Refractory Ascites
Not yet reported, Not yet reported Alexandria University 42 participants Est. completion 2022-11-12 1 site Stand-aloneOther conditions: Ascites HepaticView official trial listing → -
Suspended NCT NCT05435235
Dapagliflozin in the Prevention of Post-Coronary Angioplasty Acute Kidney Injury
Not yet reported Albert Einstein Healthcare Network 250 participants Est. completion 2025-06 1 siteOther conditions: Acute Kidney Injury, Percutaneous Coronary InterventionView official trial listing → -
Withdrawn NCT NCT05444153
Research Study to Compare Semaglutide Tablets With Empagliflozin Tablets Taken Once Daily in People With Type 2 Diabetes and Obesity
Not yet reported Novo Nordisk A/S Est. completion 2025-08-29Type 2 diabetesView official trial listing → -
Completed NCT NCT05465317
Evaluating Comparative Effectiveness of Empagliflozin in Type 2 Diabetes Population With and Without Chronic Kidney Disease
Boehringer Ingelheim 62197 participants Est. completion 2023-05-02 1 siteType 2 diabetesView official trial listing → -
Terminated NCT NCT05468203
PREVENTion With Sglt-2 Inhibition of Acute Kidney Injury in Intensive Care
Not yet reported The George Institute 51 participants Est. completion 2025-12-23 3 sitesOther conditions: Acute Kidney InjuryView official trial listing → -
Status unknown NCT NCT05477017
Evaluation of SGLT2-i Effectivness and Safety in Elderly Type 2 Diabetes Patients
University of Milan 800 participants Est. completion 2023-03 1 siteOther conditions: Type2DiabetesView official trial listing → -
Completed NCT NCT05493371
Empagliflozin in Pulmonary Arterial Hypertension
Not yet reported Amsterdam UMC, location VUmc 8 participants Est. completion 2024-11-01 1 site Stand-aloneOther conditions: Idiopathic Pulmonary Arterial HypertensionView official trial listing → -
Completed NCT NCT05504226
Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin 25 mg and Metformin
Not yet reported Handok Inc. 214 participants Est. completion 2024-06-18 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05504239
Clinical Efficacy and Safety Evaluation of Teneligliptin in Type 2 Diabetes Who Have Inadequate GlycemIc Control With Empaglyflozin and Metformin
Not yet reported Handok Inc. 235 participants Est. completion 2024-04-23 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05505994
The Efficacy and Safety of DWP16001 in Combination With Metformin in T2DM Patients Inadequately Controlled on Metformin
Not yet reported Daewoong Pharmaceutical Co. LTD. 340 participants Est. completion 2024-09 1 siteType 2 diabetes Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Disease, Endocrine System DiseasesView official trial listing → -
Active, not recruiting NCT NCT05507892
Renal Mechanism of SGLT2 Inhibition
Not yet reported University of Colorado, Denver 45 participants Est. completion 2026-12-15 2 sitesType 2 diabetesChronic kidney diseaseView official trial listing → -
Active, not recruiting NCT NCT05510115
Feasibility of Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease
Not yet reported University of Colorado, Denver 50 participants Est. completion 2026-08-01 1 site Stand-aloneOther conditions: Polycystic Kidney, Autosomal DominantView official trial listing → -
Status unknown NCT NCT05512130
Sodium-Glucose Cotransporter-2 Inhibitors: A Potential Novel Treatment for Epilepsy
Not yet reported Washington University School of Medicine 18 participants Est. completion 2023-06-30 1 site Stand-aloneOther conditions: EpilepsyView official trial listing → -
Status unknown NCT NCT05520684
Asymptomatic Bacteriuria, Urinalysis Abnormality at the Initiation of SGLT2 Inhibitors and UTI Risk
Trabzon Arakli Bayram Halil Public Hospital 120 participants Est. completion 2023-01-01 1 siteOther conditions: Type2diabetes, SGLT2 Inhibitor, Urinary Tract InfectionView official trial listing → -
Completed NCT NCT05526157
An Observational Study, Called FINEGUST, to Learn More About How People With Chronic Kidney Disease and Type 2 Diabetes Are Treated and How the Introduction of New Treatment Options, Like Finerenone, Impacts Clinical Practice
Bayer 50000 participants Est. completion 2024-09-05 5 sitesChronic kidney diseaseType 2 diabetesView official trial listing → -
Completed NCT NCT05535322
Real-world Evaluation of GLP-1 Receptor Agonists (GLP-1RA) on Efficacy and Persistence, Adherence and Therapeutic Inertia Among Type 2 Diabetes Adults With Obesity
Ana Palanca 26944 participants Est. completion 2022-09-01 1 siteType 2 diabetes Other conditions: ObesityView official trial listing → -
Completed NCT NCT05541484
Ketone Monitoring in T1D: Effect of SGLT2i During Usual Care and With Insulin Deficiency
Not yet reported Washington University School of Medicine 21 participants Est. completion 2023-12-23 1 siteOther conditions: Diabetes Mellitus, Type 1View official trial listing → -
Status unknown NCT NCT05545800
Efficacy and Safety Of Different Regimens In Patients With Type 2 Diabetes Receiving Intensive Insulin Therapy
Not yet reported Xiangya Hospital of Central South University 78 participants Est. completion 2024-06-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05553938
Effects of Acute and Chronic Empagliflozin Heart Failure
Not yet reported Yale University 60 participants Est. completion 2026-08-14 2 sites Stand-aloneHeart failureView official trial listing → -
Status unknown NCT NCT05556044
Empagliflozin for New On-set Heart Failure Study Regardless of Ejection Fraction
Not yet reported Chinese University of Hong Kong 200 participants Est. completion 2024-05-31 1 siteHeart failureView official trial listing → -
Completed NCT NCT05570305
Zibotentan and Dapagliflozin in Patients With Type 2 Diabetes and Elevated Albuminuria
Not yet reported University Medical Center Groningen 42 participants Est. completion 2025-03-05 7 sitesChronic kidney diseaseView official trial listing → -
Active, not recruiting NCT NCT05572957
LBBP as Initial Therapy in Patients With Non-ischemic Heart Failure and LBBB
Not yet reported The First Affiliated Hospital with Nanjing Medical University 50 participants Est. completion 2027-10 6 sitesHeart failure Other conditions: Non-ischemic Cardiomyopathy, Left Bundle-Branch BlockView official trial listing → -
Status unknown NCT NCT05580510
" Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD "
Not yet reported, Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 160 participants Est. completion 2024-03-29 1 site Stand-aloneHeart failure Other conditions: Congenital Heart DiseaseView official trial listing → -
Status unknown NCT NCT05584319
EMPAGUM: Effects of Empagliflozin on Gut Microbiota in Heart Failure With a Preserved Ejection Fraction
Not yet reported Zhijun Sun 100 participants Est. completion 2025-10 1 site Stand-aloneHeart failureView official trial listing → -
Active, not recruiting NCT NCT05590143
proMoting Effective Renoprotection in Cardiac sURgery Patients by Inhibition of SGLT-2
Not yet reported Amsterdam UMC 784 participants Est. completion 2025-09 6 sitesOther conditions: Acute Kidney Injury, Cardiac Surgery, Sodium-Glucose Transporter 2 InhibitorView official trial listing → -
Status unknown NCT NCT05600387
Empagliflozin on the Function of Left Atrium in Heart Failure With Mildly Reduced or Preserved Ejection Fraction
Not yet reported Zhijun Sun 100 participants Est. completion 2025-10 1 site Stand-aloneHeart failureView official trial listing → -
Status unknown NCT NCT05601336
of Sodium Glucose Cotransporter-2 Inhibitors on Metabolic, Hormonal and Clinical Parameters in PCO
Not yet reported Beni-Suef University 200 participants Est. completion 2023-07-30 1 siteOther conditions: PCOView official trial listing → -
Status unknown NCT NCT05605158
Comparative Clinical Study Between Empagliflozin Versus Pioglitazone in Non-diabetic Patients With Non-alcoholic Steatohepatitis
Not yet reported Tanta University 56 participants Est. completion 2024-11 1 siteOther conditions: Non Alcoholic SteatohepatitisView official trial listing → -
Completed NCT NCT05606913
A Study of IBI362 in Participants With Type 2 Diabetes
Not yet reported Innovent Biologics (Suzhou) Co. Ltd. 731 participants Est. completion 2024-04-09 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT05612269
SGLT2 Inhibitors and Reducing the Risk of Cancers Among Diabetics , an Observational Study
Ministry of Health, Saudi Arabia 200 participants Est. completion 2024-01-31 1 siteType 2 diabetes Other conditions: Cancer, Interleukin 6, SGLT2 InhibitorsView official trial listing → -
Completed NCT NCT05614115
Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD
Not yet reported University of Utah 62 participants Est. completion 2025-06-30 1 site Stand-aloneOther conditions: End-stage Kidney Disease, Kidney Disease, Chronic, Dialysis, Diabetic, Non-diabetic, Kidney Dysfunction, Kidney Failure, HemodialysisView official trial listing → -
Completed NCT NCT05621551
Dapagliflozin Therapy In Cardiac Surgery
Not yet reported China National Center for Cardiovascular Diseases 178 participants Est. completion 2025-06-01 1 siteType 2 diabetes Other conditions: Cardiac SurgeryView official trial listing → -
Status unknown NCT NCT05623358
PHARM Optimal-HF Pilot
Not yet reported University of British Columbia 42 participants Est. completion 2025-09-01 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT05636774
Empower the Heart of Patients With Terminal Cancer Using Cardiac Medicines Trial
Not yet reported University Hospital, Essen 97 participants Est. completion 2025-03-01 1 site Stand-aloneOther conditions: Patients With Advanced Cancer Receiving Specialized Palliative CareView official trial listing → -
Active, not recruiting NCT NCT05637853
Telemonitored Fast Track Medical Sequencing for Heart Failure With Reduced Ejection Fraction
Not yet reported Göteborg University 60 participants Est. completion 2026-08-26 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT05638880
Clinical Study to Evaluate the Possible Efficacy and Safety of Levocetirizine in Patients With Diabetic Kidney Disease
Not yet reported Mostafa Bahaa 60 participants Est. completion 2025-12-20 1 site Stand-aloneOther conditions: Diabetic NephropathiesView official trial listing → -
Completed NCT NCT05640180
An Observational Study Called FLAMINgO to Learn More About the Treatment Combination of Finerenone and SGLT2 Inhibitors in People With Long-term Kidney Disease (Chronic Kidney Disease) Together With Type 2 Diabetes by Using Routine Medical Care Data and Past Clinical Study Results
Bayer 17847 participants Est. completion 2023-12-20 1 siteChronic kidney diseaseType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT05662865
Low-CArbohydrate Diet and SGLT2-INhibitOr to Achieve Moderate Ketosis in Healthy Volunteers
Not yet reported AdventHealth Translational Research Institute 9 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Ketones, MetabolismView official trial listing → -
Active, not recruiting NCT NCT05671991
Effect of Empagliflozin on Peritoneal and Kidney Function in End Stage Renal Disease
Not yet reported Yale University 22 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: End Stage Renal Disease on DialysisView official trial listing → -
Completed NCT NCT05676684
Dapagliflozin With or Without Spironolactone for HFpEF
Not yet reported, Not yet reported Universidade do Porto 108 participants Est. completion 2024-11-29 2 sitesHeart failureView official trial listing → -
Completed NCT NCT05677334
Combination of Henagliflozin and Continuous Subcutaneous Insulin Infusion in T2DM
Not yet reported First Affiliated Hospital of Guangxi Medical University 210 participants Est. completion 2024-10-30 1 siteOther conditions: Type2diabetesView official trial listing → -
Completed NCT NCT05681273
Drug-Drug Interaction Study of Chiglitazar in Healthy Subjects.
Not yet reported Chipscreen Biosciences, Ltd. 48 participants Est. completion 2023-03-21 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT05686616
SGLT2 Inhibitor for Severe Tricuspid Regurgitation
Not yet reported Samsung Medical Center 72 participants Est. completion 2025-03-03 1 siteOther conditions: Tricuspid RegurgitationView official trial listing → -
Active, not recruiting NCT NCT05687058
Empagliflozin in ESKD - A Feasibility Study
Not yet reported, Not yet reported University of Mississippi Medical Center 24 participants Est. completion 2026-06-20 2 sites Stand-aloneHeart failure Other conditions: Kidney Failure, ChronicView official trial listing → -
Completed NCT NCT05694923
Effect of Sodium Glucose Cotransporter Inhibitors Fatty Liver Disease Patients Fatigue Assessment
Not yet reported Assiut University 55 participants Est. completion 2024-04-01 2 sites Stand-aloneOther conditions: Fatty Liver DiseaseView official trial listing → -
Completed NCT NCT05704088
SGLT2 Inhibitors Between Reno Protective Effects and Impact on Bone and Mineral Disease Among Lupus Nephritis Patients
Not yet reported Mansoura University 100 participants Est. completion 2024-01-08 1 siteOther conditions: SGLT2 INHIBITORS, Lupus Nephritis, BMDView official trial listing → -
Completed NCT NCT05727579
DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study
Not yet reported Amsterdam UMC, location VUmc 41 participants Est. completion 2025-11-30 1 siteChronic kidney disease Other conditions: Diabetes Mellitus, HypertensionView official trial listing → -
Completed NCT NCT05734690
COPILOT-HF: Cooperative Program for ImpLementation of Optimal Therapy in Heart Failure
Not yet reported Brigham and Women's Hospital 503 participants Est. completion 2025-06-09 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT05735197
Effect of Dapagliflozin on Renal Outcomes and Bone Mineral Disease in Non-diabetic Chronic Kidney Disease Patients
Not yet reported Mansoura University 100 participants Est. completion 2023-11-01 1 siteChronic kidney disease Other conditions: Bone Diseases, MetabolicView official trial listing → -
Terminated NCT NCT05737186
SGLT2 Inhibitors and Treatment of Heart Failure in Severe Renal Insufficiency
Not yet reported Peking University People's Hospital 11 participants Est. completion 2024-04-16 1 siteHeart failure Other conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT05741658
The Fontan Dapagliflozin Pilot Study
Not yet reported Johns Hopkins University 29 participants Est. completion 2026-03-10 1 siteHeart failureView official trial listing → -
Completed NCT NCT05748925
Cardio Renal Effects of SGLT2 Inhibitors Among Lupus Nephritis Patients
Not yet reported Mansoura University 84 participants Est. completion 2024-01-01 1 siteOther conditions: SLE, Lupus Nephritis, SGLT2 InhibitorsView official trial listing → -
Completed NCT NCT05757193
Ketone Pharmacokinetic Study in HFrEF
Not yet reported Duke University 20 participants Est. completion 2024-01-11 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT05757791
Sodium-Glucose Cotransporter-2 Inhibitor (SGLT2) in Major Depressive Disorder (MDD)
Not yet reported NYU Langone Health 20 participants Est. completion 2026-06-06 1 site Stand-aloneOther conditions: Major Depressive DisorderView official trial listing → -
Status unknown NCT NCT05759000
Dapa Acute Heart Failure Study
Chinese University of Hong Kong 100 participants Est. completion 2025-12-09 1 siteHeart failureView official trial listing → -
Completed NCT NCT05764811
SGLT-2 Inhibitor Effects on Cardiac and Hepatic Metabolic Profiles for the Diabetes Patients Combined With Obesity
Not yet reported National Cheng-Kung University Hospital 40 participants Est. completion 2022-12-31 1 siteOther conditions: Fatty Liver DiseaseView official trial listing → -
Status unknown NCT NCT05776043
Empagliflozin and Dapagliflozin in Patients Hospitalized for Acute Decompensated Heart Failure
Not yet reported Medical University of Warsaw 1364 participants Est. completion 2025-12-31 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT05778084
Effect of Empagliflozin on NT-Pro Brain Natriuretic Peptide in Heart Failure Patients With Reduced Ejection Fraction
Not yet reported Alexandria University 60 participants Est. completion 2024-12-15 1 siteHeart failureView official trial listing → -
Completed NCT NCT05795400
Administration of the SGLT-2 Inhibitor Dapagliflozin in the Patients With Amyloid Cardiomyopathy
Not yet reported National Medical Research Center for Cardiology, Ministry of Health of Russian Federation 50 participants Est. completion 2025-09-30 1 siteHeart failure Other conditions: Amyloid CardiomyopathyView official trial listing → -
Completed NCT NCT05799638
Strategy, Efficacy and Safety of Medication Usage in Heart Failure Patients Who Were Intolerable to GDMT
Chongqing Medical University 263 participants Est. completion 2024-06-30 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT05818995
Therapeutic Drug Use for CKD Patients
Qianfoshan Hospital 10000 participants Est. completion 2024-06-30 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT05822674
Variable Effects of Anti-diabetics on Stress Hyperglycemia Ratio
University of Diyala 80 participants Est. completion 2023-02-01 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05823870
This Study is to Compare and Evaluate the Safety and Pharmacokinetic Characteristics (PK) After Administration of DW6014 and Each Component(Empagliflozin and Metformin) in Healthy Adult Volunteers in Fast Condition.
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 32 participants Est. completion 2023-03-20 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Status unknown NCT NCT05823883
This Study is to Compare and Evaluate the Safety and Pharmacokinetic Characteristics (PK) After Administration of DW6014 and Each Component in Healthy Adult Volunteers in Fed Condition.
Not yet reported Dong Wha Pharmaceutical Co. Ltd. 30 participants Est. completion 2023-08 1 site Stand-aloneOther conditions: DW6014View official trial listing → -
Active, not recruiting NCT NCT05824923
A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure
Not yet reported Pulnovo Medical (Wuxi) Co., Ltd. 264 participants Est. completion 2027-02 1 siteHeart failureCardiovascular disease Other conditions: Pulmonary Hypertension, Hypertension, Vascular DiseasesView official trial listing → -
Completed NCT NCT05834738
Randomized, Double-blind, Placebo-controlled, Crossover Study of Atrasentan in Subjects With IgA Nephropathy
Not yet reported Novartis Pharmaceuticals 54 participants Est. completion 2025-10-29 30 sitesOther conditions: IgA Nephropathy, Immunoglobulin A NephropathyView official trial listing → -
Completed NCT NCT05857085
Novel Therapeutics and Endothelial Dysfunction in T1DM Patients
Not yet reported General and Teaching Hospital Celje 90 participants Est. completion 2023-04-20 1 siteOther conditions: Endothelial Dysfunction, Diabetes Mellitus, Type 1, Biomarkers, Endothelial Progenitor Cells, SGLT 2 Inhibitors, Incretins, Glucose Excursions, FMD, FPF, Arterial StiffnessView official trial listing → -
Active, not recruiting NCT NCT05882071
Non-interventional Study (NIS) on Sodium-glucose Co-transporter-2 Inhibitors (SGLT2i) Use in France
Boehringer Ingelheim 547150 participants Est. completion 2026-10-23 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05884866
A Study to Investigate the Mechanistic Effects of Dapagliflozin Alone or in Combination With Balcinrenone, Compared to Balcinrenone and Placebo on Body Fluid and Electrolyte Handling and Energy Metabolism in Participants Over 50 Years of Age With Chronic Kidney Disease.
Not yet reported Klinikum Nürnberg 103 participants Est. completion 2026-01-28 2 sitesChronic kidney disease Other conditions: Chronic Renal Failure, Mechanistic Effects of SGLT2 Inhibition and/ or MR Antagonism on Body Fluid and Electrolyte Homeostatis, Electrolyte and Fluid Balance ConditionsView official trial listing → -
Withdrawn NCT NCT05885074
Mechanistic Insights to Weight Loss Maintenance Through SGLT2 Inhibitors
Not yet reported University of Alabama at Birmingham Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Obesity, Weight LossView official trial listing → -
Completed NCT NCT05890131
Implementation of SGLT-2 Inhibitors in Patients With Heart Failure Through a New Digital Strategy
Not yet reported Morten Schou 5996 participants Est. completion 2026-04-07 5 sitesHeart failureView official trial listing → -
Status unknown NCT NCT05897489
SGLT2 for Heart Failure in CHD Patients
Centre Hospitalier Universitaire de Nice 100 participants Est. completion 2025-12-25 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT05905965
Efficacy of Double vs Standard Empapagliflozin Dose for METabolic syndromE tReatment
Not yet reported Collegium Medicum w Bydgoszczy 200 participants Est. completion 2026-03-31 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Completed NCT NCT05911724
Association Between Inflammatory Biomarkers in CVD Patients on Empagliflozin.
Damanhour University 180 participants Est. completion 2024-09-30 1 siteHeart failure Other conditions: Stable AnginaView official trial listing → -
Status unknown NCT NCT05914857
Evaluation of the Safety and Efficacy of SGLT2 Inhibitors in Pre-diabetic Patients
Not yet reported Yangjin 120 participants Est. completion 2025-12-01 1 sitePrediabetes Other conditions: Prediabetic StateView official trial listing → -
Completed NCT NCT05915884
The Triglyceride/Glucose Index and SGLT-2 Inhibitors
Samsun Education and Research Hospital 55 participants Est. completion 2024-01-28 1 siteOther conditions: Metabolic Disease, DiabetesView official trial listing → -
Status unknown NCT NCT05922852
Effect of Novel Antidiabetic Drug Combined With Angiotensin Receptor/Neprilysin Inhibitor on Urinary Protein
Peking University Third Hospital 1000 participants Est. completion 2024-02-28 2 sitesType 2 diabetes Other conditions: Antidiabetic DrugsView official trial listing → -
Status unknown NCT NCT05934071
Effects of the Sodium-glucose Cotransporter 2 Inhibitors+Sacubitril/Valsartan Therapy in Patients With HFrEF.
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 160 participants Est. completion 2024-12-31 1 siteHeart failure Other conditions: Ventricular Remodeling, Ventricular DysfunctionView official trial listing → -
Status unknown NCT NCT05942963
Efficacy of Empagliflozin and Pioglitazone in Diabetic Patients With NAFLD
Not yet reported Jinnah Postgraduate Medical Centre 240 participants Est. completion 2024-04 1 site Stand-aloneOther conditions: Non-Alcoholic Fatty Liver Disease, Type2diabetesView official trial listing → -
Completed NCT NCT05943899
Effect of SGLT-2 Inhibitors in Patients With T2DM and Moderate to Severe Liver Fibrosis
Diabetes Foundation, India 60 participants Est. completion 2023-06-30 1 siteOther conditions: Type2diabetesView official trial listing → -
Active, not recruiting NCT NCT05944432
CGM Use in Adults With Type 2 Diabetes on Basal Insulin
Not yet reported Abbott Diabetes Care 469 participants Est. completion 2027-11-30 25 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT05946148
Novel Antidiabetic Medications and Their Effect on Liver Steatosis (NAMELS-18)
National and Kapodistrian University of Athens 78 participants Est. completion 2021-05-31 1 siteOther conditions: Non-Alcoholic Fatty Liver Disease, Liver SteatosisView official trial listing → -
Status unknown NCT NCT05948969
Transform CV Risk in Diabetes
Not yet reported American College of Cardiology 750 participants Est. completion 2024-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT05953701
Secondary Data Analysis of Patients at Risk for CKD to Inspect CKD Prevalence, Diagnosis Rates, Diagnostic Behaviour, Treatment Patterns and Patient Characteristics
AstraZeneca 800211 participants Est. completion 2023-09-30 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT05956522
Bioequivalence Study of Empagliflozin And Linagliptin Tablets in Healthy Chinese Subjects
Not yet reported The Affiliated Hospital of Qingdao University 106 participants Est. completion 2023-01-13 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT05960617
Efficacy and Safety of Empagliflozin in GSD-Ib Patients
Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Glycogen Storage Disease Type IBView official trial listing → -
Status unknown NCT NCT05965934
Management of Volume Overload HF Patients by Individual DSR Treatment adJustment-a clinicAl inVestigation of InfusatE2.0
Not yet reported, Not yet reported Sequana Medical N.V. 33 participants Est. completion 2025-06-30 1 siteHeart failure Other conditions: Volume OverloadView official trial listing → -
Completed NCT NCT05966792
SGLT2 Inhibitors in Treating Patients With PCOS
Not yet reported Shanghai 10th People's Hospital 82 participants Est. completion 2025-06-30 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT05966818
Effect of Dapagliflozin in Non-Diabetic Patients With Nephrotic Syndrome.
Not yet reported Ain Shams University 90 participants Est. completion 2024-03-01Other conditions: Nephrotic SyndromeView official trial listing → -
Completed NCT NCT05967156
Empagliflozin in Heart Failure Dialysis Patients
Not yet reported Shahid Beheshti University of Medical Sciences 30 participants Est. completion 2025-06-03 1 site Stand-aloneHeart failure Other conditions: HemodialysisView official trial listing → -
Status unknown NCT NCT05975528
Effect of Sodium-glucose Cotransporter-2 Inhibitor in Cellular Senescence in Patients With Cardiovascular Diseases or Type 2 Diabetes
Not yet reported Yonsei University 92 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Diabetes Mellitus, Cellular Senescence, Sodium-Glucose Transporter 2 InhibitorsView official trial listing → -
Completed NCT NCT05977465
Empagliflozin in Treatment of Peripheral Diabetic Neuropathy
Not yet reported, Not yet reported Tanta University 50 participants Est. completion 2023-08-03 1 site Stand-aloneOther conditions: Diabetic Neuropathy PeripheralView official trial listing → -
Completed NCT NCT05986136
Dapagliflozin in Patients With Ulcerative Colitis
Not yet reported, Not yet reported Mostafa Bahaa 60 participants Est. completion 2026-08-20 1 siteOther conditions: Inflammatory Bowel DiseasesView official trial listing → -
Completed NCT NCT05986695
Informational Nudge to Improve Heart Failure Prescribing
Not yet reported VA Office of Research and Development 81 participants Est. completion 2024-10-31 1 siteHeart failureView official trial listing → -
Completed NCT NCT05989503
Initiation of ARNi and SGLT2i in Patients With HFrEF
Not yet reported Universidade do Porto 62 participants Est. completion 2025-07-31 5 sitesHeart failureView official trial listing → -
Completed NCT NCT05990296
Evaluating Strategies to Improve Guideline Directed Medical Therapy: The GDMT Research, Education & Assist Trial for Heart Failure Care
Not yet reported Geisinger Clinic 4306 participants Est. completion 2025-05-17 1 siteHeart failureView official trial listing → -
Completed NCT NCT05991284
Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve Regurgitation
Not yet reported Ziekenhuis Oost-Limburg 84 participants Est. completion 2026-05-09 1 siteHeart failure Other conditions: Functional Mitral RegurgitationView official trial listing → -
Completed NCT NCT05993897
Effect of Sodium Glucose Co-transporter 2 Inhibitors on Left Atrial Remodeling
Not yet reported Aswan University 60 participants Est. completion 2025-10-15 1 siteOther conditions: Atrial FibrillationView official trial listing → -
Completed NCT NCT05998837
GLUcose Transport and REnalPROtection in Chronic Kidney Disease
Not yet reported, Not yet reported IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy 34 participants Est. completion 2024-09-30 1 siteChronic kidney diseaseType 2 diabetes Other conditions: HypertensionView official trial listing → -
Active, not recruiting NCT NCT05999773
SGLT-2 Inhibitors in the Treatment of Ascites
University of Palermo 40 participants Est. completion 2026-12-31 2 sitesOther conditions: Ascites Hepatic, Cirrhosis, Liver, Diabete Type 2View official trial listing → -
Active, not recruiting NCT NCT06000462
The Effect of Dapagliflozin on Weight Loss in Obese Adults Without Diabetes
Not yet reported Oman Ministry of Health 150 participants Est. completion 2025-12-30 1 siteOther conditions: Obesity, Dapagliflozin Adverse Reaction, Weight Loss, Effect of DrugView official trial listing → -
Completed NCT NCT06000722
SGLT-i Use in Diabetic Foot Ulcer Disease
University of Leicester 21 participants Est. completion 2024-04-30 1 siteOther conditions: Diabetic Foot UlcerView official trial listing → -
Status unknown NCT NCT06007157
Sodium Glucose Cotransporter-2 Inhibitors and Salt-sensitivity in Type 2 Diabetes
Not yet reported Azienda Ospedaliero, Universitaria Pisana 30 participants Est. completion 2025-03-01 1 site Stand-aloneOther conditions: Blood Pressure, Salt; Excess, Diabete Type 2View official trial listing → -
Status unknown NCT NCT06012266
Repurposing Empagliflozin and Dapagliflozin for Paediatric Heart Failure: Translational Approach and Dose Rationale
Not yet reported Centre Hospitalier Universitaire Vaudois 12 participants Est. completion 2025-08 3 sitesHeart failureView official trial listing → -
Status unknown NCT NCT06021145
Effectiveness of Empagliflozin Added to Automated Insulin Delivery (AID) Systems in Adults With Type 1 Diabetes With Sub-optimal Glycemic Outcomes
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 46 participants Est. completion 2025-05 1 site Stand-aloneOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT06029712
Heart Failure Polypill at a Safety Net Hospital
Not yet reported University of California, San Francisco 35 participants Est. completion 2025-01-29 1 site Stand-aloneHeart failure Other conditions: HIV InfectionsView official trial listing → -
Completed NCT NCT06046560
Diabetes Remote Intervention to improVe Use of Evidence-based Medications
Not yet reported Brigham and Women's Hospital 200 participants Est. completion 2023-07-25 1 site Stand-aloneCardiovascular disease Other conditions: DiabetesView official trial listing → -
Status unknown NCT NCT06046612
Empagliflozin for Peripheral Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction
Not yet reported Maastricht University Medical Center 48 participants Est. completion 2025-02-13 1 site Stand-aloneHeart failure Other conditions: Microvascular DysfunctionView official trial listing → -
Completed NCT NCT06065280
Sodium-glucose Transport 2 Inhibitors (SGLT2i) in HFrEF Patients
Not yet reported Damanhour University 80 participants Est. completion 2024-12-30 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT06065540
A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Not yet reported Novo Nordisk A/S 2734 participants Est. completion 2026-01-06 405 sitesType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06071208
Prevent Diabetic Kidney Disease Among Egyptians
Fayoum University 10000 participants Est. completion 2028-12-14Other conditions: Diabetes Mellitus Without ComplicationView official trial listing → -
Status unknown NCT NCT06080802
The Effect of Addition of Metformin to SGLT2 In Diabetic Patients With Heart Failure With Preserved Ejection Fraction
Not yet reported, Not yet reported October University for Modern Sciences and Arts 80 participants Est. completion 2024-12-01 1 site Stand-aloneHeart failure Other conditions: Diabete Type 2View official trial listing → -
Withdrawn NCT NCT06083675
Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 Diabetes
Not yet reported Novo Nordisk A/S Est. completion 2027-05-28 100 sites Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06085703
Effects of Henagliflozin on the Brain Function in T2DM Patients With Mild Cognitive Impairment: a Randomized, Parallel Controlled Clinical Trial
Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 24 participants Est. completion 2025-06-30 1 site Stand-aloneType 2 diabetes Other conditions: Mild Cognitive ImpairmentView official trial listing → -
Status unknown NCT NCT06091475
Therapy to Maintain Remission in Dilated Cardiomyopathy
Not yet reported Imperial College London 50 participants Est. completion 2026-09-15 1 site Stand-aloneHeart failure Other conditions: Cardiomyopathy, Dilated, Cardiomyopathies, Heart DiseasesView official trial listing → -
Terminated NCT NCT06094231
Treating Patients With Renal Impairment and Altered Glucose MetAbolism With TherapeutIc Carbohydrate Restriction and Sglt2-Inhibiton - a Pilot Study
Not yet reported Department of Nephrology Clinic Ottakring Vienna 4 participants Est. completion 2026-04-13 1 siteChronic kidney diseasePrediabetes Other conditions: Diabetes Mellitus, Overweight and ObesityView official trial listing → -
Completed NCT NCT06094920
Treatment Optimization for Patients With Type 2 Diabetes Using Empagliflozin and Finerenone in a Remote Clinical Trial
Not yet reported University Medical Center Groningen 12 participants Est. completion 2025-09-24 1 siteType 2 diabetesChronic kidney disease Other conditions: Diabetes Mellitus, Diabetes, Diabetes Complications, AlbuminuriaView official trial listing → -
Status unknown NCT NCT06097585
Gliflozins on HF in Regurgitant Rheumatic Heart
Assiut University 150 participants Est. completion 2025-04-01Heart failure Other conditions: Rheumatic Heart DiseaseView official trial listing → -
Status unknown NCT NCT06098625
Empagliflozin Versus Linagliptin in Renal Ransplant Recipients With Diabetes Mellitus
Not yet reported Medanta, The Medicity, India 200 participants Est. completion 2025-12-01 Stand-aloneOther conditions: Diabetes Mellitus, Kidney Transplant; ComplicationsView official trial listing → -
Completed NCT NCT06101667
Efficacy and Safety of Endovascular Recanalization for Acute Basilar Artery Occlusion With Extended Time Window (ANGEL-BAO)
Not yet reported Beijing Tiantan Hospital 224 participants Est. completion 2026-07-01 1 siteCardiovascular disease Other conditions: Basilar Artery OcclusionView official trial listing → -
Status unknown NCT NCT06103279
Cardioprotective Empagliflozin for Cancer Patients Receiving Doxorubicin
Not yet reported, Not yet reported Ain Shams University 40 participants Est. completion 2024-08 Stand-aloneOther conditions: CancerView official trial listing → -
Completed NCT NCT06109311
A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor
Not yet reported Eli Lilly and Company 546 participants Est. completion 2025-09-15 70 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06111768
Sodium-Glucose Cotransporter-2 Inhibitor for Acute Cardiorenal Syndrome: A Feasibility Study
Not yet reported Yale University 30 participants Est. completion 2025-12-25 1 site Stand-aloneOther conditions: Cardiorenal SyndromeView official trial listing → -
Status unknown NCT NCT06113900
Assessment of Safety and Efficacy of SGLT2is Among LN Patients
Not yet reported, Not yet reported Ain Shams University 50 participants Est. completion 2025-01-30 1 siteOther conditions: Lupus NephritisView official trial listing → -
Completed NCT NCT06117137
The Impact Of SGLT2 -I on Metabolic Dysfunction -Associated Steatotic Liver Disease In Patients With Type 2 Diabetes Mellitus
Not yet reported Sohag University 150 participants Est. completion 2026-04-03 1 site Stand-aloneOther conditions: Fatty Liver, NonalcoholicView official trial listing → -
Terminated NCT NCT06124924
SGLT2 Inhibitors After Acute Kidney Injury With Indications Pilot
Not yet reported University of Minnesota 1 participants Est. completion 2024-08-16 1 site Stand-aloneOther conditions: Acute Kidney InjuryView official trial listing → -
Status unknown NCT NCT06124937
Empagliflozin to Prevent Post-Operative Atrial Fibrillation
Not yet reported Rajaie Cardiovascular Medical and Research Center 492 participants Est. completion 2024-12-30 2 sites Stand-aloneOther conditions: Post-operative Atrial Fibrillation, CABGView official trial listing → -
Status unknown NCT NCT06128096
The Effect of SGLT-2 Inhibitors on Epicardial Adipose Tissue and Cardiac Function in T2DM Patients With CAD (EpiCAD)
Clinical Research Centre, Malaysia 360 participants Est. completion 2024-12-31 1 siteCardiovascular diseaseView official trial listing → -
Status unknown NCT NCT06137430
Effect of Sodium Glucose Cotransporter 2 Inhibitiors on Left Ventricular Remodeling Among Diabetic and Non Diabetic Patients With Chronic Heart Failure
Assiut University 98 participants Est. completion 2024-12-31Other conditions: SGLT2 Inhibitiors Remodeling Effect, Chronic Heart DiseaseView official trial listing → -
Completed NCT NCT06140108
Empagliflozin vs Metformin on Metabolic Dysfunction in Polycystic Ovary Syndrome With or Without Comorbidity or Multimorbidity
Not yet reported, Not yet reported SINA Health Education and Welfare Trust 70 participants Est. completion 2024-06-30 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Weight Gain, HbA1cView official trial listing → -
Status unknown NCT NCT06140251
Investigation of Biomarker Response to SGLT2 Inhibition in Heart Failure
Queen's University, Belfast 68 participants Est. completion 2025-05-01 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT06142006
The Diabetes Staging System in Patient Aligned Care Teams
Durham VA Medical Center 120 participants Est. completion 2025-09-01 1 siteType 2 diabetes Other conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT06144788
Evaluation of Efficacy and Safety When Administered JP-2266 in Type 2 Diabetes Patients
Not yet reported Jeil Pharmaceutical Co., Ltd. 161 participants Est. completion 2024-12-23 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06145360
Evaluating the Efficacy and Safety of Empagliflozin Addition to Insulin and Oral Antidiabetic Medication (OAD) Regimen in Poorly Controlled Type 2 Diabetes and Obese Patient
Not yet reported SINA Health Education and Welfare Trust 150 participants Est. completion 2024-03-01 1 site Stand-aloneType 2 diabetes Other conditions: Glucose Metabolism Disorders, Hypoglycemic Agents, EmpagliflozinView official trial listing → -
Status unknown NCT NCT06147271
Impact of SGLT2 Inhibitors in Heart Transplant Recipients
Not yet reported Universidade Federal do Ceara 80 participants Est. completion 2025-08-01 1 siteOther conditions: Transplant; Failure, Heart, Cardiac Allograft Vasculopathy, Rejection Heart TransplantView official trial listing → -
Active, not recruiting NCT NCT06149793
SGLT2 Inhibitor Therapy in Cystic Fibrosis-related Diabetes
Not yet reported, Not yet reported University of Minnesota 8 participants Est. completion 2026-12-31 1 siteOther conditions: Cystic Fibrosis-related Diabetes, Cystic FibrosisView official trial listing → -
Completed NCT NCT06150924
Efficacy and Safety of Lorundrostat in Addition to Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i) in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria
Not yet reported Mineralys Therapeutics Inc. 60 participants Est. completion 2025-04-23 44 sites Stand-aloneChronic kidney diseaseView official trial listing → -
Completed NCT NCT06165965
To Evaluate the Safety and Pharmacokinetic Characteristics After the Administration of JT-001, JT-002 and JLP-2008
Not yet reported Jeil Pharmaceutical Co., Ltd. 48 participants Est. completion 2022-06-27 1 site Stand-aloneOther conditions: Healthy AdultView official trial listing → -
Completed NCT NCT06171802
EMPagliflozin After Aortic Valve Replacement
Not yet reported Copenhagen University Hospital, Rigshospitalet 206 participants Est. completion 2026-05-18 1 siteOther conditions: Aortic Valve StenosisView official trial listing → -
Completed NCT NCT06180109
Bioequivalence Study of Empagliflozin 25 mg Film Coated Tablets of Humanis, Turkey and Jardiance (Empagliflozin) 25 mg Film-coated Tablets of Boehringer Ingelheim International GmbH, Germany in Normal, Healthy, Adult, Human Subjects Under Fasting Condition
Not yet reported Humanis Saglık Anonim Sirketi 36 participants Est. completion 2023-10-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06187285
Efficay and Safety of Empagliflozin Versus Sitagliptin for the In-patient Management of Hyperglycemia
Not yet reported Medanta, The Medicity, India 220 participants Est. completion 2025-06-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Status unknown NCT NCT06187493
Treatment of Patients With Diabetic Kidney Disease
Not yet reported Assiut University 70 participants Est. completion 2025-12-31Chronic kidney diseaseView official trial listing → -
Status unknown NCT NCT06201000
Effect of Genetic Polymorphisms on the Clinical Response to SGLT2 Inhibitors in Heart Failure Patients
October 6 University 282 participants Est. completion 2024-09-01 1 siteHeart failure Other conditions: Genetic PolymorphismsView official trial listing → -
Completed NCT NCT06204107
A Clinical Trial to Evaluate the Food Effect on Pharmacokinetic Profiles and Safety of CKD-379
Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2023-12-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06221969
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor
Not yet reported Novo Nordisk A/S 1024 participants Est. completion 2026-04-06 197 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT06232239
Empagliflozin 10 mg Tablets Relative to Jardiance 10 mg
Not yet reported Bio-innova Co., Ltd 26 participants Est. completion 2024-04-19 Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Status unknown NCT NCT06245980
Role of SGLT2I in Patients With Myocardial Infarction
Dongying Zhang 1200 participants Est. completion 2024-03-31 1 siteCardiovascular disease Other conditions: Diabetes MellitusView official trial listing → -
Status unknown NCT NCT06251453
Impact of Sodium-glucose Cotransporter 2 Inhibitors on Post-operative Atrial Fibrillation in Cardiothoracic Surgery
Hamad Medical Corporation 3280 participants Est. completion 2025-01-31 2 sitesOther conditions: Atrial FibrillationView official trial listing → -
Active, not recruiting NCT NCT06260059
Efficacy Of Sodium Glucose Transporter Inhibitor (SGLT2I) In Adult Patients With Congenital Heart Disease
Not yet reported Anita Saraf 40 participants Est. completion 2027-06-01 3 sites Stand-aloneHeart failure Other conditions: Adult Congenital Heart DiseaseView official trial listing → -
Active, not recruiting NCT NCT06260722
Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)
Not yet reported Eli Lilly and Company 1250 participants Est. completion 2027-02 77 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06263673
Anti-Diabetic Medications to Fight PD and LBD
Not yet reported Mayo Clinic 18 participants Est. completion 2025-01-08 1 siteOther conditions: Lewy Body Dementia, Parkinson DiseaseView official trial listing → -
Completed NCT NCT06268977
Adding SGLt2 Inhibitors to Patients With Type 2 Diabetes
Not yet reported Assiut University 482 participants Est. completion 2026-01-30 1 site Stand-aloneType 2 diabetesView official trial listing → -
Withdrawn NCT NCT06280976
Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP)
Not yet reported University of Louisville Est. completion 2025-01-01 1 site Stand-aloneCardiovascular disease Other conditions: Atherosclerosis, Heart AttackView official trial listing → -
Status unknown NCT NCT06284850
Empagliflozin and Red Blood Cell 2,3-biphosphoglycerate Levels
Aristotle University Of Thessaloniki 40 participants Est. completion 2025-11 1 siteOther conditions: Hematocrit Change, Cardiovascular Prevention, Empagliflozin, SGLT2-Inhibitors, Tissue OxygenationView official trial listing → -
Completed NCT NCT06287073
JARDIANCE® Post Marketing Surveillance in Korean Patients With Chronic Kidney Disease (CKD)
Boehringer Ingelheim 299 participants Est. completion 2025-04-30 12 sitesOther conditions: Kidney Disease, ChronicView official trial listing → -
Completed NCT NCT06288529
EFFECT SGLT2 INHIBITORS ON CONTRAST MEDIUM INDUCED ACUTE KIDNEY INJURY
University of Health Sciences Balikesir Hospital Eduation and Research 975 participants Est. completion 2024-01-31 1 siteChronic kidney disease Other conditions: Type2diabetesView official trial listing → -
Active, not recruiting NCT NCT06297603
Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)
Not yet reported Eli Lilly and Company 320 participants Est. completion 2026-11 76 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT06308679
A Bioequivalence Study of Two Formulations of 10-mg Empagliflozin Tablets in Healthy Thai Volunteers Under Fasting Conditions
Not yet reported Pharma Nueva 28 participants Est. completion 2024-06-07 Stand-aloneOther conditions: Healthy VollunteerView official trial listing → -
Completed NCT NCT06313008
Empagliflozin Versus Vildagliptin in CAD Patients With T2DM
Not yet reported Damanhour University 120 participants Est. completion 2024-10-10 1 site Stand-aloneCardiovascular diseaseType 2 diabetesView official trial listing → -
Status unknown NCT NCT06326528
SGLT2 Inhibitors and Perioperative Period
Assiut University 100 participants Est. completion 2025-10-01Other conditions: Perioperative ComplicationView official trial listing → -
Status unknown NCT NCT06337409
Bioequivalence Study of Empagliflozin 25 mg Film-coated Tablets in Healthy Thai Volunteers
Not yet reported International Bio service 30 participants Est. completion 2024-07-13 Stand-aloneOther conditions: Healthy VolunteerView official trial listing → -
Completed NCT NCT06339788
Pharmacokinetics of HD-P023 and Co-administration of Teneligliptin and Empagliflozin High in Healthy Volunteers
Not yet reported Handok Inc. 40 participants Est. completion 2024-06-12 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT06341842
Potential Protective Role of SGLT-2 Inhibitors for Chemotherapy-induced Cardiotoxicity
Not yet reported Fondazione IRCCS Policlinico San Matteo di Pavia 316 participants Est. completion 2025-04-19 1 siteOther conditions: Breast CancerView official trial listing → -
Active, not recruiting NCT NCT06342141
Empagliflozin for No-reflow Phenomenon in PCI for STEMI
Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 162 participants Est. completion 2026-06-15 1 site Stand-aloneOther conditions: STEMI, No-Reflow PhenomenonView official trial listing → -
Status unknown NCT NCT06344247
Comparison of the Efficacy and Safety of SGLT2i and GLP-1 Receptor Agonists in Obese Patients With Kidney Disease
Not yet reported RenJi Hospital 48 participants Est. completion 2025-12-01 1 site MixedChronic kidney disease Other conditions: ObesityView official trial listing → -
Status unknown NCT NCT06344910
PRagmatic Study Of Messaging to Providers of Patients With Heart Failure in Amsterdam UMC
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 900 participants Est. completion 2025-12 2 sitesHeart failureView official trial listing → -
Completed NCT NCT06350123
Efficacy, Safety and Tolerability of Balcinrenone/Dapagliflozin Compared to Dapagliflozin in Adults With Chronic Kidney Disease
Not yet reported AstraZeneca 324 participants Est. completion 2025-05-09 92 sitesChronic kidney diseaseView official trial listing → -
Status unknown NCT NCT06350487
The Efficacy of Enavogliflozin in Heart Failure With Preserved Ejection Fraction
Not yet reported Samsung Medical Center 154 participants Est. completion 2026-06-30 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT06350903
Suppression With Empagliflozin as an Alternative To High-Fat Low-Carbohydrate Diet for Myocardial F-fluorodeoxyglucose Positron Emission Tomography (FDG-PET) Imaging
Not yet reported Matthieu Pelletier-Galarneau, MD MSc 16 participants Est. completion 2024-11-01 1 siteOther conditions: Myocardial SuppressionView official trial listing → -
Completed NCT NCT06370247
First-time Usage of SGLT2 Inhibitors in Type 2 Diabetic Patients Who Are Fasting During Ramadan: Safety and Efficacy
Not yet reported Sohag University 60 participants Est. completion 2023-09-25 1 siteType 2 diabetes Other conditions: SGLT2 Inhibitors, First Time Use, Fasting in RamadanView official trial listing → -
Completed NCT NCT06374043
Decentralized N=1 Study: A Feasible Approach to Evaluate Individual Therapy Response to Dapagliflozin.
Not yet reported University Medical Center Groningen 20 participants Est. completion 2022-09-13 2 sitesType 2 diabetesChronic kidney disease Other conditions: Diabetes Mellitus, Diabetes, Diabetes Complications, Albuminuria, ProteinuriaView official trial listing → -
Active, not recruiting NCT NCT06391450
Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease (EMPA-PKD)
Not yet reported Hannover Medical School 44 participants Est. completion 2027-05 1 site Stand-aloneOther conditions: Autosomal Dominant Polycystic KidneyView official trial listing → -
Completed NCT NCT06393348
Efficacy and Safety of HRS-7535 Tablets in T2DM Subjects Poorly Controlled With Metformin and SGLT2i.
Not yet reported Shandong Suncadia Medicine Co., Ltd. 155 participants Est. completion 2025-03-13 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT06401343
Use of SGLT2i in noHCM With HFpEF
Not yet reported China National Center for Cardiovascular Diseases 94 participants Est. completion 2025-08-01 1 site Stand-aloneHeart failure Other conditions: Hypertrophic CardiomyopathyView official trial listing → -
Status unknown NCT NCT06417320
Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 Years
Not yet reported Mansoura University 60 participants Est. completion 2025-08 1 siteOther conditions: Nephrotic Syndrome in ChildrenView official trial listing → -
Completed NCT NCT06432751
Pre-operative Exposure to SGLT2 Inhibitors and Post-operative Acute Renal Failure in Cardiac Surgery
Hospices Civils de Lyon 500 participants Est. completion 2024-05-10 1 siteOther conditions: Acute Kidney Injury, Cardiac Surgery, Sodium/Glucose Cotransporter Inhibitor 2View official trial listing → -
Not yet recruiting NCT NCT06434025
IV Iron and SGLT2 Inhibitor on Ventricular Function and Myocardial Iron Content in Heart Failure With Iron Deficiency
Not yet reported Hospital de Clinicas de Porto Alegre 99 participants Est. completion 2026-11-24 1 site Stand-aloneHeart failure Other conditions: Iron DeficienciesView official trial listing → -
Completed NCT NCT06435858
Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease
Not yet reported Cantonal Hospital Graubuenden 16 participants Est. completion 2025-12-01 2 sites Stand-aloneOther conditions: Autosomal Dominant Polycystic Kidney DiseaseView official trial listing → -
Status unknown NCT NCT06442280
SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution in Acute HF
Not yet reported University of Palermo 544 participants Est. completion 2026-03-30Heart failure Other conditions: Diabetes Type 2View official trial listing → -
Not yet recruiting NCT NCT06448130
Henagliflozin's Impact on Prediabetes Remission
Not yet reported Shandong Provincial Hospital 984 participants Est. completion 2027-12 50 sitesPrediabetesType 2 diabetes Other conditions: Prediabetic State, Glucose Metabolism DisordersView official trial listing → -
Status unknown NCT NCT06449235
Real-World Evaluation of Omarigliptin for Type 2 Diabetes Meliitus in Bangladesh
Not yet reported Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders 938 participants Est. completion 2025-06 1 siteOther conditions: Type2diabetesView official trial listing → -
Completed NCT NCT06450262
Bioequivalence Study to Compare Empagliflozin/ Metformin HCl 12.5mg/1000mg Film-coated Tablets
Not yet reported Humanis Saglık Anonim Sirketi 36 participants Est. completion 2024-03-05 1 site Stand-aloneOther conditions: Type2diabetesView official trial listing → -
Terminated NCT NCT06450522
Post-Discharge Pharmacist-led Rapid Medication Optimization for Heart Failure (Post-Discharge PHARM-HF)
Not yet reported University of British Columbia 12 participants Est. completion 2025-02-21 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT06453161
Pre-operative Exposure to SGLT2 Inhibitors and Post-operative Acute Renal Failure in Cardiac Surgery: a Retrospective Monocentric Cohort Study
Hospices Civils de Lyon 500 participants Est. completion 2024-05-10 1 siteOther conditions: Acute Kidney Injury, Cardiac, SurgeryView official trial listing → -
Completed NCT NCT06453577
Pharmacokinetics of Bisoprolol and SGLT2i in Acutely Decompensated Heart Failure
Universität des Saarlandes 33 participants Est. completion 2026-07-08 1 siteHeart failureView official trial listing → -
Completed NCT NCT06469645
The Role of SGLT2i in Management of Moderate AS
Not yet reported, Not yet reported University of East Anglia 104 participants Est. completion 2026-07-24 1 site Stand-aloneOther conditions: Moderate Aortic Valve StenosisView official trial listing → -
Completed NCT NCT06475586
Effect of Semaglutide on the Psoriatic Lesions in Patients With Type 2 Diabetes Mellitus
Not yet reported University of Banja Luka 30 participants Est. completion 2024-06-10 1 siteOther conditions: Psoriasis Vulgaris, Diabetes Type 2View official trial listing → -
Completed NCT NCT06483243
Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetic of CKD-501, D745, and D150 for Healthy Subjects in Fed State.
Not yet reported Chong Kun Dang Pharmaceutical 45 participants Est. completion 2024-05-17 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06491953
SGLT2-inhibitors on PC-AKI
Shenyang Northern Hospital 3600 participants Est. completion 2026-05-28 1 siteOther conditions: Impact of SGLT2-inhibitors on PC-AKI in ACS Patients Receiving Invasive StrategyView official trial listing → -
Status unknown NCT NCT06492655
To Evaluate the Food Effect on Pharmacokinetic Profiles and Safety in Healthy Volunteers
Not yet reported Chong Kun Dang Pharmaceutical 28 participants Est. completion 2024-08-08Type 2 diabetesView official trial listing → -
Status unknown NCT NCT06503601
The Impact of Genetic Polymorphism on the Echocardiographic Parameters and Cardiac Fibrosis Markers in Response to Empagliflozin Treatment Among Patients With Heart Failure
Ain Shams University 92 participants Est. completion 2025-10-01 1 siteHeart failureView official trial listing → -
Enrolling by invitation NCT NCT06519448
Reducing Non-Alcoholic Steatohepatitis
Not yet reported Military University Hospital, Prague 30 participants Est. completion 2027-12-31 1 site Stand-aloneType 2 diabetes Other conditions: Non-alcoholic Steatohepatitis, Liver Diseases, Fibrosis, LiverView official trial listing → -
Active, not recruiting NCT NCT06527846
Post Marketing Surveillance of JARDIANCE in Chronic Kidney Disease
Boehringer Ingelheim 1024 participants Est. completion 2027-03-31 1 siteOther conditions: Kidney Disease, ChronicView official trial listing → -
Active, not recruiting NCT NCT06531824
EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)
Not yet reported Boehringer Ingelheim 11000 participants Est. completion 2026-12-31 558 sites Stand-aloneOther conditions: Kidney Disease, ChronicView official trial listing → -
Completed NCT NCT06534411
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Both
Not yet reported Novo Nordisk A/S 1023 participants Est. completion 2026-07-09 163 sitesType 2 diabetesView official trial listing → -
Status unknown NCT NCT06535529
Acetazolamide Versus Dapagliflozin in Acute Decompensated Heart Failure Patients
Not yet reported Helwan University 60 participants Est. completion 2025-09-01 1 siteHeart failureView official trial listing → -
Completed NCT NCT06571591
Efficacy and Safety of Pioglitazone Combination Therapy in Type 2 Diabetes Patients on a Background of Empagliflozin With Metformin
Not yet reported Celltrion 606 participants Est. completion 2026-05-04 1 siteType 2 diabetesView official trial listing → -
Status unknown NCT NCT06578676
To Evaluate the Safety and Pharmacokinetic Interaction Between HODO-22251 and HODO-22252 in Healthy Adults
Not yet reported Hyundai Pharm 56 participants Est. completion 2024-11-30 1 site Stand-aloneType 2 diabetes Other conditions: DyslipidemiasView official trial listing → -
Status unknown NCT NCT06585761
Effect of Sodium Glucose Co-tansporter 2 Inhibitors (SGLT2I) on Inflammatory and Oxidative Stress Markers Level in Heart Failure Patients
Kafrelsheikh University 60 participants Est. completion 2025-06-30 1 siteHeart failureView official trial listing → -
Status unknown NCT NCT06604611
Colchicine in Patients With Heart Failure With Preserved Ejection Fraction and Inflammation
Not yet reported Dongying Zhang 200 participants Est. completion 2026-03-31 1 site Stand-aloneHeart failure Other conditions: Chronic Inflammation, Inflammation, ColchicineView official trial listing → -
Completed NCT NCT06618976
Antithrombotic Activities of Sotagliflozin vs. Empagliflozin
Not yet reported Icahn School of Medicine at Mount Sinai 17 participants Est. completion 2026-02-10 1 siteOther conditions: ThrombosisView official trial listing → -
Completed NCT NCT06632561
Benefits of Empagliflozin in Patients With Heart Failure and Reduced Ejection Fraction Without Diabetes Mellitus
Not yet reported Ashraf Wasfy Beshay Aziz 74 participants Est. completion 2022-03-14 1 site Stand-aloneHeart failureView official trial listing → -
Not yet recruiting NCT NCT06637618
Does the Sequence of Heart Failure Medication Matter
Not yet reported Aarhus University Hospital 16000 participants Est. completion 2030-02-01Heart failureView official trial listing → -
Not yet recruiting NCT NCT06641128
The Possible Efficacy and Protective Effect of Empagliflozin in Rheumatoid Arthritis Patients Treated with Methotrexate
Not yet reported Tanta University 44 participants Est. completion 2025-04-10 1 siteOther conditions: Rheumatoid Arthritis (RA), Methotrexate Induced Nephrotoxicity, Methotrexate Adverse ReactionView official trial listing → -
Not yet recruiting NCT NCT06643442
Repurposing Empagliflozin for DMD-associated Cardiomyopathy in Children 6-18 Years of Age
Not yet reported Sebastiano Lava 12 participants Est. completion 2027-03-31 1 site Stand-aloneOther conditions: DMD-associated Dilated CardiomyopathyView official trial listing → -
Completed NCT NCT06649344
A Study of HRS9531 Versus Semaglutide Once Weekly as Add-on Therapy to Metformin Monotherapy or in Combination With SGLT2 Inhibitors in Participants With Type 2 Diabetes
Not yet reported Fujian Shengdi Pharmaceutical Co., Ltd. 884 participants Est. completion 2026-07-18 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06668753
Effect of SGLT2 Inhibitors on NAFLD in Type 2 Diabetic Patients with Diabetic Nephropathy
Assiut University 114 participants Est. completion 2027-07-30MASLDChronic kidney diseaseView official trial listing → -
Active, not recruiting NCT NCT06683053
Evaluation of the Use of Empagliflozin in Patients with HF with PEF in a Cardiology Outpatient Department
Not yet reported Conrado Roberto Hoffmann Filho 90 participants Est. completion 2025-02-28 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT06688123
Efficacy and Safety of SHR-3167 and Insulin Glargine in Type 2 Diabetes Subjects
Not yet reported Jiangsu HengRui Medicine Co., Ltd. 275 participants Est. completion 2026-04-22 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT06690723
Vitamin D and SGLT-2 Inhibitor in CPAP-naive Obstructive Sleep Apnea
Not yet reported University Malaysia Sarawak 160 participants Est. completion 2024-09-03 1 siteObstructive sleep apneaView official trial listing → -
Completed NCT NCT06697353
An Observational Study to Learn More About the Real-world Outcomes in Patients With Heart Failure Who Initiate Treatment With Vericiguat in Japan
Bayer 4936 participants Est. completion 2025-09-19 1 siteHeart failureView official trial listing → -
Completed NCT NCT06700213
Guideline Directed Medical Therapy in Patients With Heart Failure
Massachusetts General Hospital 300 participants Est. completion 2025-09-22 1 siteHeart failureView official trial listing → -
Completed NCT NCT06708091
Real-world Clinical Effectiveness and Patient Insight Associated With Adding Sodium Glucose Co-transporter 2 Inhibitor to Gliclazide Modified Release
Servier Affaires Médicales 537 participants Est. completion 2024-05-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06721442
Effect of Dapagliflozin on Electrocardiographic Parameters in Type 2 Diabetes Patients: DAPA - ECG Study
Not yet reported Beneficência Portuguesa de São Paulo 174 participants Est. completion 2024-07-10 2 sitesOther conditions: Arrhythmias, Cardiac, Diabetes MellitusView official trial listing → -
Status unknown NCT NCT06731231
SGLT2i in Diabetic Patients with Renal Transplantation
Not yet reported, Not yet reported Ain Shams University 72 participants Est. completion 2025-01 1 siteOther conditions: Post-transplant Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT06739486
Efficacy of Sodium Glucose Cotransporter 2 Inhibitors on Non-Alcoholic Fatty Liver Disease
Assiut University 100 participants Est. completion 2025-12-20MASLD Other conditions: Non Alcholic Fatty Liver Disease, Hepatic Steatosis, Hepatic FibrosisView official trial listing → -
Completed NCT NCT06750458
Dapagliflozin Versus Dexamethasone Role in Pre-operative Management of Non- Diabetic Brain Tumor Patients
Not yet reported Tanta University 75 participants Est. completion 2026-09-20 1 siteOther conditions: Glioma, Dapagliflozin (Forxiga), DexamethasoneView official trial listing → -
Completed NCT NCT06753994
Continuous Ketone Monitoring in People With Type 1 Diabetes Using SGLT2 Inhibitors
Not yet reported McGill University 24 participants Est. completion 2026-04-01 1 site Stand-aloneOther conditions: Diabetes, Type1diabetes, T1DView official trial listing → -
Completed NCT NCT06759922
Glimepiride, Empagliflozin, and Sitagliptin With Metformin for Type 2 Diabetes
Not yet reported Bahria University 172 participants Est. completion 2025-06-30 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06762223
Henagliflozin on Liver Fibrosis in Patients with MASLD and T2DM
Not yet reported Xiqiao Zhou 190 participants Est. completion 2026-12-31 1 site Stand-aloneMASLDType 2 diabetesView official trial listing → -
Completed NCT NCT06762314
Efficacy and Safety of Empagliflozin or Semaglutide in Overweight/Obese Patients With Type 1 Diabetes
Not yet reported Mostafa Bahaa 114 participants Est. completion 2026-01-20 1 siteOther conditions: DiabetesView official trial listing → -
Completed NCT NCT06766500
Pharmacokinetics and Bioequivalence Study of Empagliflozin+Metformin Hydrochloride 5 mg/850 mg Film-coated Tablets (Gedeon Richter Plc., Hungary) Versus Synjardy® 5 mg/850 mg Film-coated Tablets (Boehringer Ingelheim International GmbH, Germany)
Not yet reported Gedeon Richter Plc. 64 participants Est. completion 2025-02-28 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06778967
A Phase III Clinical Study to Evaluate the Efficacy and Safety of GZR18 Injection in Adult Type 2 Diabetes Mellitus
Not yet reported Gan & Lee Pharmaceuticals. 1100 participants Est. completion 2026-12-11 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06792968
Pharmacokinetics and Bioequivalence Study of Empagliflozin+Metformin Hydrochloride 5 mg/1000 mg Film-coated Tablets (Gedeon Richter Plc., Hungary) Versus Synjardy 5 mg/1000 mg Film-coated Tablets (Boehringer Ingelheim International GmbH, Germany)
Not yet reported Gedeon Richter Plc. 64 participants Est. completion 2025-04-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06794710
Early Identification and Treatment of Rare Cardiomyopathy Cohorts
Not yet reported RenJi Hospital 300 participants Est. completion 2027-09-30 1 site Stand-aloneOther conditions: Hypertrophic Cardiomyopathy (HCM), Dilated Cardiomyopathy (DCM), Metabolic Cardiomyopathy, Restrictive CardiomyopathyView official trial listing → -
Completed NCT NCT06797115
Hydroxyl Free Radical Associated Effects of SGLT-2 Inhibitors in Type 2 Diabetes
University of Pecs 40 participants Est. completion 2024-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT06812429
Effects of Sodium-Glucose Co-transporter 2 Inhibitors on Inflammation
Not yet reported Washington University School of Medicine 6 participants Est. completion 2025-04-05 1 siteOther conditions: InflammationView official trial listing → -
Active, not recruiting NCT NCT06813222
Anemia-Related Outcomes in Patients With CKD Treated With Dapagliflozin
Damanhour University 100 participants Est. completion 2025-03-01 1 siteChronic kidney disease Other conditions: AnemiaView official trial listing → -
Terminated NCT NCT06818305
Efficacy and Safety of Finerenone and Empagliflozin in Delaying Renal Function Progression After Radical Nephrectomy in High-Risk CKD Patients: A Multicenter RCT
Not yet reported Jinling Hospital, China 10 participants Est. completion 2025-10-01 1 site Stand-aloneChronic kidney disease Other conditions: Renal Cell Carcinoma (Kidney Cancer), Renal Cell Carcinoma (RCC), NephrectomyView official trial listing → -
Completed NCT NCT06823856
Pharmacokinetics and Bioequivalence Study of Empagliflozin+Metformin Hydrochloride 12.5 mg/1000 mg Film-coated Tablets (Gedeon Richter Plc., Hungary) Versus Synjardy 12.5 mg/1000 mg Film-coated Tablets (Boehringer Ingelheim International GmbH, Germany)
Not yet reported Gedeon Richter Plc. 64 participants Est. completion 2025-05-21 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT06825156
Metabolic and Renal Outcomes in Cardiac Surgery Patients Receiving SGLT2 Inhibitors
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 60 participants Est. completion 2023-05-26 1 site Stand-aloneOther conditions: Acute Kidney InjuryView official trial listing → -
Not yet recruiting NCT NCT06825676
Guideline-diRected MAnagement for Chronic Kidney Disease: EValuation of an Education Progamme in a National Cluster Randomized Controlled Trial
Not yet reported Guangdong Provincial People's Hospital 1800 participants Est. completion 2027-03 1 siteCardiovascular disease Other conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT06828731
Evaluation of Empagliflozin vs Standard Care in Veterans With Prediabetes
Not yet reported Charles George VA Medical Center 60 participants Est. completion 2025-09-05 1 site Stand-alonePrediabetesView official trial listing → -
Not yet recruiting NCT NCT06838507
Incidence, Characterisation and Outcome-relevance of Perioperative SGLT2 Inhibitor Associated Ketoacidosis
Heinrich-Heine University, Duesseldorf 2000 participants Est. completion 2026-12 1 siteOther conditions: SGLT2 Inhibitor, Ketoacidosis, EugylcemicView official trial listing → -
Terminated NCT NCT06844669
HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed Therapy
Not yet reported Washington University School of Medicine 7 participants Est. completion 2026-05-07 1 site Stand-aloneOther conditions: HER2-positive Breast Cancer, HER2+ Breast CancerView official trial listing → -
Not yet recruiting NCT NCT06851845
Clinical Outcomes of C3 Glomerulopathy and IC-MPGN in Russia: Hybrid Retrospective - Prospective Study
Novartis Pharmaceuticals 100 participants Est. completion 2028-02-01Other conditions: Kidney DiseasesView official trial listing → -
Completed NCT NCT06851962
Impact of Pharmacogenetic-Guided Treatment on Type 2 Diabetes.
Not yet reported Fundación para la Investigación del Hospital Clínico de Valencia 92 participants Est. completion 2026-06-30 3 sites Added to GLP-1Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT06858436
SGLT2 Inhibitor Utilization Re-perfusion Therapy
Not yet reported Taichung Veterans General Hospital 150 participants Est. completion 2027-10-31Cardiovascular diseaseView official trial listing → -
Completed NCT NCT06888505
Dapagliflozin to Prevent Anthracycline-Induced Cardiotoxicity
Not yet reported Hawler Medical University 94 participants Est. completion 2025-09-06 1 siteOther conditions: Anthracyclines-Induced Cardiotoxicity, CardiotoxicityView official trial listing → -
Completed NCT NCT06889350
Pharmacokinetics and Safety of HD-P023 and Co-administration of Teneligliptin and Empagliflozin High in Healthy Volunteers
Not yet reported Handok Inc. 40 participants Est. completion 2025-05-07 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Active, not recruiting NCT NCT06901609
Effect of Genetic Polymorphism on the Clinical Outcome to SGLT2 Inhibitors in Heart Failure Patients
Ain Shams University 200 participants Est. completion 2025-07-01 1 siteHeart failure Other conditions: Cardiac Fibrosis, Cardiac RemodelingView official trial listing → -
Completed NCT NCT06902493
Impact of Prior SGLT2 Inhibitors Use on the Development and Progression of Sepsis-Associated Acute Kidney Injury
University of Jazan 664 participants Est. completion 2025-03-01 1 siteOther conditions: Sepsis, Septic Shock, Acute Kidney InjuryView official trial listing → -
Completed NCT NCT06915870
Comparison of Empagliflozin and Dapagliflozin in Patients With Heart Failure Taking Standard Treatment
Not yet reported Fatima Maqsood 108 participants Est. completion 2025-01-13 1 site Stand-aloneHeart failure Other conditions: Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT06922656
Can the Addition of Pioglitazone to SGLT2 Inhibitor in Type 1 Diabetic Patients Amplify the Decrease in HbA1c and Prevent the Increase in Plasma Ketone Concentration?
Not yet reported Dasman Diabetes Institute 60 participants Est. completion 2027-01-15 3 sitesOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT06926660
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease
Not yet reported Boehringer Ingelheim 492 participants Est. completion 2026-08-14 157 sites Stand-aloneChronic kidney diseaseView official trial listing → -
Completed NCT NCT06932159
Bioequivalence Study to Compare Empagliflozin + Linagliptin 25 mg/5 mg Film-coated Tablets Versus Glyxambi 25 mg/ 5 mg Film-coated Tablets
Not yet reported Humanis Saglık Anonim Sirketi 40 participants Est. completion 2025-04-08 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT06933355
Acute Effects of SGLT2 Inhibitor on Kidney Allograft Oxygen Tension
Not yet reported Odense University Hospital 8 participants Est. completion 2026-06-01 1 siteOther conditions: Kidney Transplantation Recipients, Magnetic Resonance Imaging (MRI), Sodium-Glucose Transporter 2 Inhibitors, Non-Diabetic Patients, Randomized Controlled Trial, Placebo Control DesignView official trial listing → -
Not yet recruiting NCT NCT06946628
New Triple Therapy in Newly Diagnosed Type 2 Diabetes
Not yet reported Sun Yat-sen University 296 participants Est. completion 2030-12-31 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT06951737
Evaluation Of The Effect Of SGLT-2 Inhibitors On Atrial Fibrillation Recurrence In Diabetic Patients
Bursa Postgraduate Hospital 120 participants Est. completion 2024-10-02 1 siteOther conditions: Diabetes Mellitus, Atrial Fibrillation (AF)View official trial listing → -
Completed NCT NCT06952231
Effect of Sitagliptin and Empagliflozin in Combination With Metformin on Hs-CRP Levels in Patients With Type 2 Diabetes Mellitus
Not yet reported University of Lahore 50 participants Est. completion 2025-01-05 1 siteOther conditions: Diabetes MellitusView official trial listing → -
Completed NCT NCT06962826
A Study in Healthy People to Test How Empagliflozin is Taken up in the Body When Taken as a Whole Tablet or Dissolved in Water and Mixed With Food
Not yet reported Boehringer Ingelheim 14 participants Est. completion 2025-09-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT06964607
Impact of Sodium Glucose Co-transporter 2-Inhibitors on Clinical Outcome and Left Ventricular Function in Patients Presented by Acute Myocardial Infarction
Tanta University 80 participants Est. completion 2024-04-01 1 siteCardiovascular disease Other conditions: Sodium-glucose Cotransporter 2, Inhibitors, Clinical Outcome, Left VentriculeView official trial listing → -
Active, not recruiting NCT NCT07003191
Metformin Hydrochloride and Empagliflozin Tablets in the Treatment of Type 2 Diabetes
Sun Yat-sen University 2600 participants Est. completion 2025-12-31 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07022379
Sodium-Glucose Cotransporter 2 Inhibitor Use in a National Heart Failure Telemonitoring Program
Satelia 13660 participants Est. completion 2024-12-31 1 siteHeart failureView official trial listing → -
Not yet recruiting NCT NCT07027969
Metabolic Surgery for Atrial Fibrillation Elimination
Not yet reported Ali Aminian 100 participants Est. completion 2030-03-31 1 siteOther conditions: Atrial Fibrillation, Obesity and Obesity-related Medical ConditionsView official trial listing → -
Not yet recruiting NCT NCT07032116
YiqiJiangzhuoHuoxueTongluo Method to Delay the Occurrence of End-stage Renal Disease in Diabetic Kidney Disease--Study1
Liu Hongfang 4472 participants Est. completion 2028-07-31 5 sitesChronic kidney diseaseView official trial listing → -
Completed NCT NCT07035457
A Study in Healthy Men to Compare the Amount of Vicadrostat and Empagliflozin in the Blood When Taken Separately and Together
Not yet reported Boehringer Ingelheim 15 participants Est. completion 2025-08-15 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Not yet recruiting NCT NCT07035834
SGLT-2 Inhibitors on Albuminuria in Chronic Kidney Disease Patients With Lupus Nephritis and ANCA- Associated Vasculitis
Not yet reported Federico II University 40 participants Est. completion 2026-12Other conditions: Lupus Nephritis (LN), ANCA Associated Vasculitis (AAV)View official trial listing → -
Completed NCT NCT07039890
To Compare and Evaluate the Oral Bioavailability of Empagliflozin + Linagliptin 10 mg/5 mg Filmcoated Tablets With That of Glyxambi 10 mg/ 5 mg Film-coated Tablets in Healthy, Adult, Human Subjects Under Fasting Conditions.
Not yet reported Humanis Saglık Anonim Sirketi 40 participants Est. completion 2025-06-05 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07044700
Real-world Comparative Effectiveness and Safety of Jardiance in Chinese Patients With Heart Failure of Reduced Ejection Fraction
Boehringer Ingelheim 5000 participants Est. completion 2028-12-31 1 siteHeart failureView official trial listing → -
Not yet recruiting NCT NCT07047508
Real-world Study to Describe the Effectiveness and Safety Outcomes of Jardiance in Chinese Patients With Heart Failure and Preserved Ejection Fraction
Boehringer Ingelheim 3000 participants Est. completion 2028-12-31Heart failure Other conditions: Preserved Ejection FractionView official trial listing → -
Withdrawn NCT NCT07057479
Phase III Trial of SGLT2 Inhibitor and Thiazolidinedione Fixed-Dose Combination vs. Monotherapy in Type 2 Diabetes Patients on Metformin
Not yet reported Eurofarma Laboratorios S.A. Est. completion 2028-02 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07060417
Vascular Effects of SGLT2i in Non-diabetic CKD
Not yet reported VA Office of Research and Development 52 participants Est. completion 2029-09-30 1 siteChronic kidney diseaseView official trial listing → -
Active, not recruiting NCT NCT07063316
SGLT2 Inhibitors and Renal Anemia in Japan: RWD
Boehringer Ingelheim 15000 participants Est. completion 2026-12-25 1 siteChronic kidney diseaseView official trial listing → -
Enrolling by invitation NCT NCT07065357
Treating the Metabolic Syndrome With a Sodium-glucose Cotransporter-2 Inhibitor
Not yet reported The University of Hong Kong 160 participants Est. completion 2026-12 1 site Stand-aloneMetabolic syndromeView official trial listing → -
Not yet recruiting NCT NCT07073053
The Role of Glucagon-Like Peptide-1 Receptor Agonists in Coronary Artery Diseases and Their Potential Mechanisms
Not yet reported Taipei Veterans General Hospital, Taiwan 60 participants Est. completion 2028-07-31 1 site Added to GLP-1Type 2 diabetes Other conditions: Glucagon-Like Peptide-1 Receptor Agonists, Coronary Arterial Disease (CAD)View official trial listing → -
Completed NCT NCT07076056
Clinical Trial to Evaluate the Efficacy and Safety of DW1026C1 or DW1026C2
Not yet reported Daewon Pharmaceutical Co., Ltd. 230 participants Est. completion 2024-06-19 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07084038
Effect of Glycosuria on Urinary Protein in Patients With Chronic Kidney Disease Treated With SGLT2 Inhibitors
Yuanjun Yang 300 participants Est. completion 2026-06-30 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT07102719
Pharmacokinetics and Safety of HD-P023 and Co-administration of Teneligliptin and Empagliflozin High in Healthy Volunteers
Not yet reported Handok Inc. 40 participants Est. completion 2025-10-20 1 siteOther conditions: Healthy VolunteersView official trial listing → -
Not yet recruiting NCT NCT07105917
SLGT2i for Neuroprotection in Patients With Acute Ischemic Stroke
Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 1050 participants Est. completion 2026-11-01 Stand-aloneCardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07108985
Effect of Add-on SGLT2i, TZD, or Combination Therapy in Type 2 Diabetes Patients on DPP4 Inhibitors
Not yet reported Yonsei University 100 participants Est. completion 2030-08-31 1 siteType 2 diabetes Other conditions: Hyperglycemia, Insulin ResistanceView official trial listing → -
Completed NCT NCT07112274
Empagliflozin on Patients With Preserved Heart Failure
Not yet reported Damanhour University 50 participants Est. completion 2025-07-30 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT07120828
The Role of CYP8B1 Polymorphisms in Modulating the Biochemical Pathways Affected by SGLT2 Inhibitors in T2DM and Obesity
Not yet reported Erbil Polytechnic University 260 participants Est. completion 2026-03-15 1 site Stand-aloneType 2 diabetes Other conditions: Obese Diabetics, Obese Patients (BMI ≥ 30 kg/m²)View official trial listing → -
Active, not recruiting NCT NCT07127406
Postoperative Euglycemic Ketoacidosis Frequency in Sodium-Glucose Cotransporter-2 Inhibitor Users
Kocaeli City Hospital 300 participants Est. completion 2027-06-01 1 siteOther conditions: Diabetic Ketoacidosis, Postoperative CareView official trial listing → -
Completed NCT NCT07128654
A Bioequivalence Study of CT-L02 Compared to Co-administration (CTL0201 and CTL0202) in Healthy Volunteers
Not yet reported Celltrion 40 participants Est. completion 2025-10-26 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT07133399
A Study in Healthy People to Test How 2 Different Formulations of a Combination Treatment (Vicadrostat and Empagliflozin) Are Taken up in the Body and How Food Influences the Amount of the Medicines in the Blood
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2025-10-22 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Not yet recruiting NCT NCT07146880
Empagliflozin as a Potential Therapeutic Solution for Patients With Brugada Syndrome
Not yet reported National Taiwan University Hospital 10 participants Est. completion 2027-09-21 1 site Stand-aloneOther conditions: Brugada Syndrome (BrS)View official trial listing → -
Not yet recruiting NCT NCT07155694
Role of Finerenone in African American Veterans With Diabetic Kidney Disease
Not yet reported Washington D.C. Veterans Affairs Medical Center 30 participants Est. completion 2027-08 1 siteChronic kidney diseaseView official trial listing → -
Not yet recruiting NCT NCT07156539
A Phase 3 Study of HS-20094 in Patients With T2DM
Not yet reported Jiangsu Hansoh Pharmaceutical Co., Ltd. 546 participants Est. completion 2027-05-30 2 sitesType 2 diabetesView official trial listing → -
Completed NCT NCT07169981
Effect of Empagliflozin 10 vs 25 mg on LV Remodeling in Diabetic Patients With Anterior STEMI With Reduced LVEF
Not yet reported Ain Shams University 200 participants Est. completion 2025-06-17 1 site Stand-aloneHeart failure Other conditions: Diabete Mellitus, Remodeling, Left VentricleView official trial listing → -
Not yet recruiting NCT NCT07180745
Empagliflozin Versus Statins in Non-Alcoholic Fatty Liver Disease
Not yet reported Badr University 400 participants Est. completion 2026-03-01 1 siteMASLDMASHView official trial listing → -
Not yet recruiting NCT NCT07186153
Effect of Sodium Glucose Co-transporter 2 Inhibitors on Left Atrial Remodeling in Diabetic Patients
Assiut University 100 participants Est. completion 2026-11-01Other conditions: SGLT 2 InhibitorsView official trial listing → -
Active, not recruiting NCT NCT07188545
Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)
Ohio State University 23280000 participants Est. completion 2029-06-30 1 siteMetabolic syndromeView official trial listing → -
Active, not recruiting NCT NCT07198191
SGLT2 Inhibitor Use After Acute Myocardial Infarction in Patients With Type 2 Diabetes: A Nationwide Cohort Study
Yonsei University 200000 participants Est. completion 2026-08-30 1 siteCardiovascular diseaseType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07204743
Efficacy and Safety of Dapagliflozin in Children With Proteinuria
Not yet reported Al-Quds University 10 participants Est. completion 2026-08 1 site Stand-aloneOther conditions: SGLT 2 Inhibitors, Pediatric Kidney Disease, Proteinuric Diseases, Dapagliflozin (Forxiga)View official trial listing → -
Not yet recruiting NCT NCT07211802
CKM For Safe Use of SGLT2i in Type 1 Diabetes
Not yet reported University of California, San Diego 52 participants Est. completion 2030-12-31 1 site Added to GLP-1Other conditions: Type 1 Diabetes (T1D)View official trial listing → -
Completed NCT NCT07213895
Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCL 25mg/5mg/1000mg Extended-Release Tablets Versus Trijardy® XR Extended Release Film Coated Tablets
Not yet reported Humanis Saglık Anonim Sirketi 14 participants Est. completion 2025-09-18 1 site Stand-aloneType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07225465
Evaluating Safe Ketone Thresholds To Minimise Ketosis in People With Type 1 Diabetes Using Dapagliflozin
Not yet reported St Vincent's Hospital Melbourne 115 participants Est. completion 2028-02 4 sitesOther conditions: Type 1 Diabetes MellitusView official trial listing → -
Active, not recruiting NCT NCT07241702
EFFECT OF HYBRID CLOSED-LOOP SYSTEMS ON CARDIOVASCULAR MARKERS IN TYPE 1 DIABETES.
Attikon Hospital 100 participants Est. completion 2025-12-01 1 siteOther conditions: Type 1 DiabetesView official trial listing → -
Completed NCT NCT07247656
The Efficacy and Safety of Empagliflozin - Linagliptin and Empagliflozin- Metformin Therapy in Reduction of Body Weight in Type 2 Diabetic Patients .
Not yet reported Bahria University 200 participants Est. completion 2023-05-01 1 siteOther conditions: Diabete MellitusView official trial listing → -
Not yet recruiting NCT NCT07262723
Levosimendan in Acute Decompensated Heart Failure
Not yet reported, Not yet reported Chittagong Medical College 332 participants Est. completion 2026-12-30 6 sitesHeart failureView official trial listing → -
Completed NCT NCT07266766
Bioequivalence Study to Compare Empagliflozin / Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg
Not yet reported Humanis Saglık Anonim Sirketi 40 participants Est. completion 2025-10-06 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07269197
Association of SGLT2 Inhibitors Therapy With Elastographic and Molecular Markers of Liver Injury in Type 2 Diabetes
Josip Juraj Strossmayer University of Osijek 67 participants Est. completion 2025-10-10 1 siteType 2 diabetes Other conditions: Non-Alcoholic Fatty Liver DiseaseView official trial listing → -
Not yet recruiting NCT NCT07270198
Mechanisms Underlying SGLT2i Kidney Effect in DKD Progression
Not yet reported Mario Negri Institute for Pharmacological Research 100 participants Est. completion 2027-08 1 siteChronic kidney diseaseView official trial listing → -
Not yet recruiting NCT NCT07272057
SGLT2 Inhibitors and Survival in Lung Cancer Patients With Diabetes
Not yet reported Shanghai Chest Hospital 200 participants Est. completion 2026-11-07Other conditions: Lung CancerView official trial listing → -
Not yet recruiting NCT NCT07294495
Effect of Henagliflozin on Myocardial Fibrosis in Non-Obstructive HCM: A Randomized, Double-Blind, Placebo-Controlled Trial Using 68Ga/18F-FAPI PET/CMR
Not yet reported Shanghai East Hospital 150 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: HCM - Hypertrophic CardiomyopathyView official trial listing → -
Not yet recruiting NCT NCT07295522
Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap?
Not yet reported IRCCS Policlinico S. Donato 368 participants Est. completion 2028-06-08 13 sites Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT07302464
Sodium Glucose Co-Transporter 2 Inhibitors on Estimated Glomerular Filtration Rate in Diabetic Versus Non-Diabetic Chronic Kidney Disease Patients
Ain Shams University 60 participants Est. completion 2025-06-01 1 siteChronic kidney disease Other conditions: Sodium Glucose Co-Transporter 2 Inhibitors, Estimated Glomerular Filtration Rate, DiabetesView official trial listing → -
Active, not recruiting NCT NCT07303556
Improving Cardiovascular Disease Diagnosis and Treatment in Kazakhstan Using Metabolic Correction With GLP-1 Drugs
Not yet reported Nazarbayev University 120 participants Est. completion 2026-11-01 1 site Added to GLP-1Heart failure Other conditions: Diabete Type 2, Arterial HypertensionView official trial listing → -
Not yet recruiting NCT NCT07311109
A Prospective, Single-center, Randomized Controlled Clinical Study Evaluating the Efficacy and Safety of Hyperbaric Oxygen Therapy as an Adjunctive Treatment for Chronic Heart Failure
Not yet reported Fujian Medical University 150 participants Est. completion 2028-12-31 1 site Stand-aloneHeart failureView official trial listing → -
Not yet recruiting NCT NCT07311551
A Comparison of Effectiveness, Safety, and Cost-effectiveness of Dapagliflozin and Empagliflozin in Patients With Type 2 Diabetes Mellitus and High Body Mass Index (BMI)
Not yet reported Bhavya Bhavya, MD 112 participants Est. completion 2026-12 Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07325435
Beta Cell Function in Type 2 Diabetes: Differential Effects of SGLT2 Inhibitors and GLIP-Receptor Agonists
Not yet reported MaryAnn Banerji 60 participants Est. completion 2028-06-30 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07331220
Pulmonary Artery Denervation for Heart Failure With Preserved Left Ventricular Ejection Fraction
Not yet reported Nanjing First Hospital, Nanjing Medical University 310 participants Est. completion 2028-12-30 1 site Stand-aloneHeart failureView official trial listing → -
Completed NCT NCT07332156
Lung Cancer Risk in Type 2 Diabetes With COPD: SGLT2 Inhibitors vs. Sulfonylureas
Samsung Medical Center 21692 participants Est. completion 2023-12-31Type 2 diabetes Other conditions: COPD (Chronic Obstructive Pulmonary Disease), Lung Cancer (Diagnosis)View official trial listing → -
Not yet recruiting NCT NCT07334145
Effect of SGLT2 Inhibitors on Anemic CKD Patients
Sohag University 60 participants Est. completion 2026-09-01 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT07338331
Comparative Effects of Aspirin, Metformin and SGLT2 Inhibitors on Liver Enzymes, Lipid Profile, and FibroScan Findings in Non-Alcoholic Fatty Liver Disease
Not yet reported Galala University 80 participants Est. completion 2025-09-19 1 siteOther conditions: Diabete Type 2, Non Alcoholic Fatty LiverView official trial listing → -
Not yet recruiting NCT NCT07342764
Dapagliflozin Versus Metformin for the Management of Antipsychotic-Induced Weight Gain: A Pragmatic Pilot Randomized Controlled Trial
Not yet reported Sultan Qaboos University 110 participants Est. completion 2028-12 1 siteOther conditions: Antipsychotic-induced Weight Gain (AIWG), Antipsychotic-induced Weight GainView official trial listing → -
Completed NCT NCT07344922
SGLT2 Inhibitors in Non-Diabetic CKD: Effects on Vascular Calcification and Anemia
Not yet reported Mansoura University 100 participants Est. completion 2023-12-01 1 siteChronic kidney disease Other conditions: Anemia, Cardiovascular CalcificationView official trial listing → -
Not yet recruiting NCT NCT07348484
Urinary Biomarker-Based Diagnostic and Monitoring System for Chronic Kidney Disease and Real-World Effectiveness of SGLT2 Inhibitors
Instituto de Investigación Biomédica de Salamanca 300 participants Est. completion 2028-03 1 siteChronic kidney diseaseView official trial listing → -
Active, not recruiting NCT NCT07348718
Rubix LS Diabetic Kidney Disease (DKD) Registry Study
Rubix LS 2000 participants Est. completion 2026-04-01 1 siteChronic kidney diseaseView official trial listing → -
Not yet recruiting NCT NCT07349979
PCI With GDMT Versus GDMT Alone for Patients With Ischemic Cardiomyopathy and Reduced LVEF
Not yet reported Nanjing First Hospital, Nanjing Medical University 1154 participants Est. completion 2028-01-30 1 siteHeart failureCardiovascular disease Other conditions: Stable GDMTView official trial listing → -
Not yet recruiting NCT NCT07351643
CCTA Evaluation of SGLT2i-related Pericoronary Fat Changes in Non-diabetic ACS Patients Without HF
Not yet reported Shenyang Northern Hospital 110 participants Est. completion 2026-12-30 1 siteOther conditions: ACS (Acute Coronary Syndrome), SGLT2 InhibitorsView official trial listing → -
Not yet recruiting NCT NCT07351864
Finerenone Plus SGLT2 Inhibitors in Heart Failure
Not yet reported Mansoura University 60 participants Est. completion 2026-07-31 1 siteHeart failureView official trial listing → -
Not yet recruiting NCT NCT07355088
Precision Subtyping and Prognostic Study of Heart Failure Based on Multi-Omics Integration and Clinical Indicators: A Prospective Single-Center Cohort Study
Xinjiang Medical University 600 participants Est. completion 2028-03-01 1 siteHeart failureView official trial listing → -
Not yet recruiting NCT NCT07360457
GLP1 Analogues and the Risk of Osteoarthritis
Beni-Suef University 390 participants Est. completion 2027-03-01OsteoarthritisView official trial listing → -
Completed NCT NCT07363707
A Study Between Dapagliflozin and Empagliflozin Effect on NAFLD in Patients With Type 2 Diabetes.
Not yet reported Beni-Suef University 108 participants Est. completion 2024-03-01 1 siteMASLDView official trial listing → -
Not yet recruiting NCT NCT07365358
Evaluate the Efficacy and Safety of Empagliflozin or Glimepiride Combination Therapy in Type 2 Diabetes Mellitus Patients
Not yet reported Chong Kun Dang Pharmaceutical 200 participants Est. completion 2027-08 1 site Stand-aloneOther conditions: Diabete Type 2View official trial listing → -
Completed NCT NCT07367555
Effect Of Sodium Glucose Co-Transporter-2 (SGLT-2) Inhibitors on Body Mass Index After 3 Months of Use in Diabetic Patients
Not yet reported Ariba Shafiq 360 participants Est. completion 2025-03-31 1 site Stand-aloneOther conditions: Diabete MellitusView official trial listing → -
Completed NCT NCT07372118
Bioequivalence Study to Compare Empagliflozin / Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg in Fast Condition
Not yet reported Humanis Saglık Anonim Sirketi 32 participants Est. completion 2026-01-07 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT07379788
ARNI Combined With SGLT2 Inhibitors on Functional Mitral Regurgitation Remodeling
Not yet reported Rehab Werida 180 participants Est. completion 2026-03-01 1 siteHeart failureView official trial listing → -
Not yet recruiting NCT NCT07391267
Pathogenesis of Chronic Kidney Disease Associated With Metabolic Dysfunction- Associated Fatty Liver Disease (MAFLD) and Treatment Response of Oral Semaglutide.
Not yet reported Institute of Liver and Biliary Sciences, India 90 participants Est. completion 2028-12-31 1 site Added to GLP-1Chronic kidney disease Other conditions: MAFLDView official trial listing → -
Not yet recruiting NCT NCT07392788
Early Gliflozin for Elderly Patients With Acute Decompensated Heart Failure in the Emergency Department
Not yet reported Centre Hospitalier Universitaire de Besancon 144 participants Est. completion 2028-02Heart failureView official trial listing → -
Not yet recruiting NCT NCT07417306
A Study of HDM1005 in Participants With T2DM Not Controlled With Metformin Alone or in Combination With a Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor
Not yet reported Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. 912 participants Est. completion 2027-12-31 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07421518
Ketone Monitoring Approaches for Diabetic Ketoacidosis Risk Mitigation in People With T1D on Adjunctive SGLT-2 Inhibitors
Not yet reported AdventHealth Translational Research Institute 75 participants Est. completion 2030-04 1 siteType 2 diabetes Other conditions: Type 1 DiabetesView official trial listing → -
Not yet recruiting NCT NCT07424430
Real-world Canadian Retrospective Study Evaluating Longitudinal Semaglutide Use on Cardio-Kidney-Metabolic Outcomes
LMC Diabetes & Endocrinology Ltd. 400 participants Est. completion 2026-05Type 2 diabetes Other conditions: Diabetes (DM), Obesity (Disorder)View official trial listing → -
Not yet recruiting NCT NCT07436663
Comparative Study Between (SGLT-2i) and (DPP-4i) in the Prevention of DIC
Not yet reported Tanta University 150 participants Est. completion 2027-12-01Other conditions: Breast CancerView official trial listing → -
Not yet recruiting NCT NCT07441187
Efficacy and Safety of Henagliflozin, Retagliptin, and Metformin Extended-Release Tablets in Chinese Patients With Type 2 Diabetes Mellitus
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 300 participants Est. completion 2027-12-31Type 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07450417
Effect of Early Empagliflozin Initiation in Cardiogenic Shock.
Central Hospital, Nancy, France 418 participants Est. completion 2026-04 1 siteOther conditions: Cardiogenic ShockView official trial listing → -
Enrolling by invitation NCT NCT07452913
Metformin, Empagliflozin With Sitagliptin vs Linagliptin in Type 2 Diabetes
Not yet reported Bahria University 110 participants Est. completion 2026-06-30 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07465926
Early Add-On Combination of GLP-1 Receptor Agonist and SGLT2 Inhibitor in People With Cardiovascular-Kidney-Metabolic Stage 2-3
Chung Shan Medical University 451036 participants Est. completion 2026-01-31Metabolic syndromeCardiovascular diseaseType 2 diabetes Other conditions: Kidney Disease, Obesity & OverweightView official trial listing → -
Active, not recruiting NCT NCT07471802
Monitoring of the Sympathetic/Vagal Balance Through Multiparametric Analysis of Heart Rate Variability (HRV)
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 150 participants Est. completion 2031-09-01 1 siteHeart failure Other conditions: Diabete Type 2, Kidney Disease, Chronic, Cardiorenal SyndromeView official trial listing → -
Not yet recruiting NCT NCT07472920
Empagliflozin Adjunctive Therapy in Bipolar Depression
Not yet reported University of Sao Paulo 20 participants Est. completion 2026-12 1 site Stand-aloneOther conditions: Bipolar Disorder, Bipolar Depression, Insulin ResistanceView official trial listing → -
Active, not recruiting NCT NCT07478575
Effects of SGLT2 Inhibitors on Erythropoiesis in Heart Failure
University Medical Centre Ljubljana 85 participants Est. completion 2026-12-31 1 siteHeart failure Other conditions: Anemia, Renal InsufficiencyView official trial listing → -
Completed NCT NCT07479108
Bioequivalence Study of EMPAGLIFLOZIN (25 mg Tablets) vs. JARDIANCE® (25 mg Tablets), in Healthy Research Subjects, Under Fasting Conditions
Not yet reported ADIUM 32 participants Est. completion 2024-12-11 1 site Stand-aloneOther conditions: BioequivalanceView official trial listing → -
Not yet recruiting NCT NCT07488689
Assessing the Efficacy of Dapagliflozin as a Vasculoprotective Treatment in Septic Shock Patients With Microcirculatory Dysfunction
Not yet reported University Hospital, Strasbourg, France 568 participants Est. completion 2030-07 1 siteOther conditions: Septic ShockView official trial listing → -
Not yet recruiting NCT NCT07516847
Dapagliflozin for Anemia in Lower-Risk Myelodysplastic Syndromes
Not yet reported Seug yun Yoon, MD 37 participants Est. completion 2029-09Other conditions: Myelodysplastic Syndromes (MDS), AnemiaView official trial listing → -
Not yet recruiting NCT NCT07527390
CANagliflozin In DIALysis Patients
Not yet reported University Medical Center Groningen 10 participants Est. completion 2027-01-30 1 siteChronic kidney disease Other conditions: DialysisView official trial listing → -
Completed NCT NCT07531108
Effects of Empagliflozin-Metformin, Sitagliptin-Metformin, and Metformin on Adipokines in Type 2 Diabetes
Not yet reported Hawler Medical University 186 participants Est. completion 2025-11-27 1 siteType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07533747
PRECISE Phenotyping to Guide Therapies for Coronary Microvascular Dysfunction
Not yet reported King's College London 100 participants Est. completion 2031-05 Stand-aloneOther conditions: Coronary Microvascular Dysfunction (CMD)View official trial listing → -
Not yet recruiting NCT NCT07537088
Efficacy and Safety of Triple Therapy With Dulaglutide, SGLT2 Inhibitors, and Finerenone in Chinese Adults With Type 2 Diabetes and Chronic Kidney Disease
Not yet reported First Affiliated Hospital of Wannan Medical College 468 participants Est. completion 2027-07 Added to GLP-1Type 2 diabetesChronic kidney diseaseView official trial listing → -
Completed NCT NCT07539584
Adiponectin in Patients With Metabolic Disorders
Not yet reported Moscow Regional Research and Clinical Institute (MONIKI) 130 participants Est. completion 2024-04-08 1 site Stand-aloneType 2 diabetes Other conditions: Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD)View official trial listing → -
Completed NCT NCT07541456
Empagliflozin Versus Non-SGLT2 Oral Drugs for Blood Pressure in Type 2 Diabetes
Not yet reported Dr. Zarmina Younes 300 participants Est. completion 2025-11-08 1 site Stand-aloneType 2 diabetes Other conditions: HypertensionView official trial listing → -
Not yet recruiting NCT NCT07547878
Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)
Not yet reported Baylor Research Institute 64 participants Est. completion 2029-03-31 1 siteChronic kidney diseaseType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07555106
Dapagliflozin in Living-Donor Kidney Transplant Recipients
Not yet reported University of Guadalajara 54 participants Est. completion 2026-09-30 1 siteOther conditions: Kidney Transplant, Kidney Transplant FailureView official trial listing → -
Completed NCT NCT07556094
Empagliflozin and CPAP in Adults With Heart Failure and Obstructive Sleep Apnea.
Not yet reported Medical University of Bialystok 70 participants Est. completion 2025-05-09 1 site Stand-aloneObstructive sleep apneaHeart failure Other conditions: Sleep Apnea Syndrome, ObstructiveView official trial listing → -
Not yet recruiting NCT NCT07558902
RDN for Heart Failure
Not yet reported Shanghai Golden Leaf MedTec Co. Ltd 20 participants Est. completion 2027-09-13 1 siteHeart failureView official trial listing → -
Completed NCT NCT07563647
Association Between Diastolic Dysfunction and Erectile Dysfunction and the Effect of Tadalafil and SGLT2 Inhibitors on Them in Men With Metabolic Syndrome
Not yet reported Kafrelsheikh University 60 participants Est. completion 2026-03-17 1 site Stand-aloneMetabolic syndrome Other conditions: Erectile Dysfunction, Left Ventricular Diastolic DysfunctionView official trial listing → -
Completed NCT NCT07566299
Early GLP-1 Receptor Agonist and SGLT2 Inhibitor Add-On Strategies in Adults With Obesity, Type 2 Diabetes, Cardiovascular-Kidney-Metabolic Syndrome Stage 2-3, and Metabolic Dysfunction-Associated Steatotic Liver Disease
Chung Shan Medical University 118805 participants Est. completion 2026-03-31Type 2 diabetesMetabolic syndromeMASLDView official trial listing → -
Not yet recruiting NCT NCT07580638
Chiglitazar Added to SGLT-2 Inhibitors for Type 2 Diabetes
Chipscreen Biosciences, Ltd. 3550 participants Est. completion 2028-07-18Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07585526
Safety and Efficacy of Finerenone in Metabolic Dysfunction Associated Steatotic Liver Disease(MASLD/NAFLD) Related Cirrhosis Patients With Ascites in Prevention of Chronic Kidney Disease.
Not yet reported Institute of Liver and Biliary Sciences, India 160 participants Est. completion 2028-03-31 1 siteMASLDChronic kidney diseaseView official trial listing → -
Active, not recruiting NCT NCT07586371
Proteinuria in Normotensive Diabetic Patients: ARBs Alone or in Combination of SGLT2i
Not yet reported, Not yet reported Dr Mudassar Saeed Pansota 60 participants Est. completion 2026-08-05 1 site Stand-aloneOther conditions: Proteinuria, Diabetes (DM)View official trial listing → -
Completed NCT NCT07591077
SGLT2 Adjunct in T1D
Not yet reported, Not yet reported Ain Shams University 86 participants Est. completion 2026-02-20 1 siteOther conditions: Type 1 Diabetes, Nephropathy, DiabeticView official trial listing → -
Not yet recruiting NCT NCT07594509
Perioperative Vericiguat in Patients Undergoing Cardiovascular Surgery
Not yet reported Nanjing Medical University 600 participants Est. completion 2030-12-31 1 siteOther conditions: Cardio Vascular Disease, Cardiopulmonary BypassView official trial listing → -
Completed NCT NCT07599293
Emulation of the EMPEROR-Preserved Trial Using Healthcare Claims Data
Brigham and Women's Hospital 39614 participants Est. completion 2026-06-19 1 siteHeart failureType 2 diabetesView official trial listing → -
Completed NCT NCT07599345
Emulation of the EMPEROR-Reduced Trial Using Healthcare Claims Data
Brigham and Women's Hospital 23955 participants Est. completion 2026-06-15 1 siteHeart failureView official trial listing → -
Active, not recruiting NCT NCT07602348
Assessment of Retinal-Angio Findings In Patients With Diabetes Type II Treated With Novel Antidiabetic Therapies
University of Athens 40 participants Est. completion 2026-05-31 1 siteOther conditions: Diabetic Retinopathy, GLP-1, SGLT 2 Inhibitors, Endothelial Dysfunction, Microvascular Circulation, Retinal Vascular DiseasesView official trial listing → -
Completed NCT NCT07610174
Effects of Dapagliflozin, Semaglutide, and Their Combination in Heart Failure Patients With Prosthetic Heart Valves
Not yet reported Kafrelsheikh University 160 participants Est. completion 2026-04-29 1 siteHeart failure Other conditions: Heart Valve ProsthesisView official trial listing → -
Completed NCT NCT07627048
Influence of Gut Microbiota on the Development of Type 2 Diabetes Mellitus and Personalization of Diabetes-lowing Therapy
Pirogov Russian National Research Medical University 100 participants Est. completion 2022-04-10 1 siteType 2 diabetesView official trial listing → -
Completed NCT NCT07628556
Antidiabetic Medications and Risk of Cancer
University of Pecs 74799 participants Est. completion 2025-12-30 1 siteOther conditions: CancerView official trial listing → -
Not yet recruiting NCT NCT07630454
Tirzepatide on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With Obesity and HFpEF
Not yet reported Yunlong Wang 602 participants Est. completion 2029-12-01 1 site Added to GLP-1Heart failure Other conditions: Atrial Fibrillation, TirzepatideView official trial listing → -
Completed NCT NCT07633015
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 5 mg / 850 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-04-29 1 site Stand-aloneOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Completed NCT NCT07633028
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 850 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-04-08 1 site Stand-aloneOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Completed NCT NCT07633041
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 1000 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-04-04 1 site Stand-aloneOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Completed NCT NCT07633054
Clinical Study to Determine Bioequivalence Between Two Oral Medications of Empagliflozin/Metformin in 12.5 mg / 500 mg Tablets Under Fed Conditions.
Not yet reported ADIUM 42 participants Est. completion 2025-11-24 1 site Stand-aloneOther conditions: Bioequivalence Study in Healthy SubjectsView official trial listing → -
Not yet recruiting NCT NCT07635953
New Triple Combination Therapy in Newly Diagnosed Type 2 Diabetes
Not yet reported Sun Yat-sen University 296 participants Est. completion 2031-07-01 1 site Stand-aloneOther conditions: Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT07668739
Efficacy of Verciguat in TR and RV Failure
Not yet reported Daejeon St. Mary's hospital 100 participants Est. completion 2028-05-31 1 site Stand-aloneOther conditions: HFrEF, Tricuspid Regurgitation (TR)View official trial listing → -
Not yet recruiting NCT NCT07678151
Finerenone and Empagliflozin Combination in Obesity With Hypertension: A 12-Week Prospective, Parallel-design, Double-blind, Randomized, Placebo-controlled Trial
Not yet reported Heart Health Research Center 260 participants Est. completion 2027-08-31 2 sites Stand-aloneOther conditions: Hypertension (HTN)View official trial listing → -
Active, not recruiting NCT NCT07678203
Dapagliflozin to Reduce the Decline in Renal Function in Patients Newly Diagnosed With Lupus Nephritis
Not yet reported, Not yet reported Hospital Civil Juan I. Menchaca 30 participants Est. completion 2027-02-26 1 siteChronic kidney disease Other conditions: Lupus Nephritis (LN), SGLT 2 Inhibitors, Systemic Lupus ErythematosusView official trial listing → -
Not yet recruiting NCT NCT07682350
SGLT2i Effect on PTDM Development and Kidney Allograft Function in Non-diabetic Kidney Transplant Recipients: A Randomized, Doubleblind, Placebo Controlled, National Multicenter Trial
Not yet reported Odense University Hospital 184 participants Est. completion 2029-10-01 3 sitesOther conditions: Kidney Transplant Recipient, Sodium Glucose Co-Transporter 2 Inhibitors, Non-Diabetic Patients, Randomized Controlled Trial (RCT), Placebo Control Design, Post Transplant Diabetes MellitusView official trial listing → -
Not yet recruiting NCT NCT07687212
Randomized Double-blind Controlled Clinical Study of SGLT-2i Combined With Probiotic Preparations in Elderly Patients With HFpEF
Not yet reported, Not yet reported The First Affiliated Hospital of Air Force Medicial University 162 participants Est. completion 2027-11 1 siteHeart failureView official trial listing → -
Completed NCT NCT07691203
Bioequivalence Study to Compare Empagliflozin/Linagliptin/Metformin HCl 25 mg/5 mg/1000 mg Extended Release Tablet Versus Trijardy® XR 25 mg/5 mg/1000 mg Extended- Release Tablets
Not yet reported Humanis Saglık Anonim Sirketi 36 participants Est. completion 2026-07-01 1 site Stand-aloneType 2 diabetesCardiovascular diseaseView official trial listing → -
Completed NCT NCT07694115
Bioequivalence Study to Compare Empagliflozin/ Metformin 25 mg/ 1000 mg Extended-Release Tablet Versus Synjardy XR Tablets 25mg/1000mg
Not yet reported Humanis Saglık Anonim Sirketi 40 participants Est. completion 2026-07-01 1 site Stand-aloneType 2 diabetesView official trial listing → -
Active, not recruiting NCT NCT07694596
SGLT2 Inhibitors and Cognitive Function in Adults With Type 2 Diabetes (SaveMinD)
Not yet reported University of Primorska 200 participants Est. completion 2028-04-20 1 site Stand-aloneType 2 diabetes Other conditions: Cognitive DysfunctionView official trial listing → -
Completed NCT NCT07708025
Oral Iron for the Management of Iron Deficiency Anemia in SGLT2i-Treated Heart Failure Patients
Not yet reported Universidade do Porto 55 participants Est. completion 2026-03-15 1 siteHeart failure Other conditions: AnemiaView official trial listing → -
Not yet recruiting NCT NCT07708610
Preadmission GLP-1 Receptor Agonist Plus SGLT2 Inhibitor Use and Early Outcomes After Pneumonia Hospitalization in Adults With Type 2 Diabetes
Chung Shan Medical University 71775 participants Est. completion 2026-08-31 1 site Stand-aloneType 2 diabetes Other conditions: PneumoniaView official trial listing → -
Active, not recruiting NCT NCT07716774
SGLT-2 Inhibitors and Lower Urinary Tract Symptoms
Marmara University 40 participants Est. completion 2026-12-01 1 siteOther conditions: SGLT2 Inhibitors, Lower Urinary Track Symptoms, Overactive BladderView official trial listing → -
Completed NCT NCT07719621
Evaluation of the Risk of Heart Failure in Patients With Chronic Kidney Disease and Type 2 Diabetes Mellitus
Aeterna Medical Solutions SL 100000 participants Est. completion 2026-08-20 1 siteChronic kidney diseaseType 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07723820
Glycemic Velocity and Early Retinal Microvascular Change With GLP-1RA Versus SGLT2i Initiation in Type 2 Diabetes (GLIDE)
Thammasat University Hospital 126 participants Est. completion 2027-09-01 1 siteType 2 diabetes Other conditions: Diabetic Retinopathy (DR)View official trial listing → -
Not yet recruiting NCT NCT07728318
Efficacy, Safety, and Treatment Satisfaction of Once-Weekly Tirzepatide in Obese Type 2 Diabetic Patients
Not yet reported Akhtar Saeed Medical and Dental College 52 participants Est. completion 2027-05-12Type 2 diabetesView official trial listing → -
Not yet recruiting NCT NCT07734558
Evaluation of Neuregulin-4 (NRG4) Levels in Obese and Non-Obese Patients With Type 2 Diabetes Mellitus
GÜLDEN ANATACA 125 participants Est. completion 2026-12-30 1 siteType 2 diabetes Other conditions: Insulin ResistanceView official trial listing → -
Not yet recruiting NCT NCT07749014
Timing of Empagliflozin in Primary PCI: Pre-Reperfusion Versus Post-Reperfusion Versus Placebo in South Asian STEMI Patients
Not yet reported Rehman Medical Institute - RMI 480 participants Est. completion 2027-09-30 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07756294
Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease
Not yet reported Wake Forest University Health Sciences 30 participants Est. completion 2028-04 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Not yet recruiting NCT NCT07758023
Achieving Optimal Medical Therapy Through Percutaneous Treatment of Secondary Mitral Regurgitation to Improve Outcome in Patients With HFrEF
Not yet reported University Medical Center Mainz 520 participants Est. completion 2030-09-30 Stand-aloneHeart failure Other conditions: Mitral Regurgitation FunctionalView official trial listing → -
Not yet recruiting NCT NCT07766109
Discontinuation or Continuation of SGLT-2 Inhibitors Before Cardiac Surgery
Not yet reported University Hospital, Toulouse 434 participants Est. completion 2029-01 1 siteHeart failure Other conditions: Cardiac SurgeryView official trial listing → -
Not yet recruiting NCT NCT07770737
Cardioprotective Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists in Korean Patients With Type 2 Diabetes
Dongtan Sacred Heart Hospital 100 participants Est. completion 2027-12-31 1 siteType 2 diabetesCardiovascular diseaseHeart failureView official trial listing → -
Not yet recruiting NCT NCT07775846
QUARTET-DKD: Quadruple Therapy for Type 2 Diabetic Nephropathy
Not yet reported Huijie Zhang 820 participants Est. completion 2029-06-30 1 site Stand-aloneChronic kidney diseaseView official trial listing → -
Not yet recruiting NCT NCT07785128
Efficacy and Safety of Mycophenolate Mofetil in Refractory IgA Nephropathy
Not yet reported Shaheed Suhrawardy Medical College and Hospital 104 participants Est. completion 2027-08-31 3 sitesOther conditions: IgA NephropathyView official trial listing → -
Not yet recruiting NCT NCT07799441
Neurovascular Effects of Empagliflozin
Not yet reported Kanokwan Bunsawat 100 participants Est. completion 2029-01 1 site Stand-aloneOther conditions: Blood Pressure, Endothelial DysfunctionView official trial listing → -
Not yet recruiting NCT NCT07803471
Yiqi Fumai Lyophilized Injection for Chronic Heart Failure Caused by Coronary Heart Disease
Not yet reported China Academy of Chinese Medical Sciences 100 participants Est. completion 2027-10 4 sitesHeart failure Other conditions: Coronary Heart Disease (CHD)View official trial listing → -
Completed NCT NCT07804641
Safety and Efficacy of the Combination Therapy of Fucoidan / Fucoxanthin / L-carnitine in Patients With Diabetic Nephropathy.
Not yet reported Taipei Medical University WanFang Hospital 63 participants Est. completion 2026-03-11 1 siteChronic kidney diseaseView official trial listing → -
Not yet recruiting NCT NCT07810998
Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome
Not yet reported, Not yet reported Tanta University 60 participants Est. completion 2027-05-10Other conditions: Poly Cystic Ovary SyndromeView official trial listing → -
Completed NCT NCT07814482
Effect of Sacubitril-Valsartan on Estimated Pulmonary Artery Systolic Pressure in Patients With Heart Failure With Reduced Ejection Fraction Heart Failure
Not yet reported Aswan University 59 participants Est. completion 2026-07-12 1 siteOther conditions: PASPView official trial listing → -
Not yet recruiting NCT NCT07815808
Cardioprotective Effect of Empagliflozin in Breast Cancer Patients
Not yet reported Tanta University 150 participants Est. completion 2028-12-31 1 siteOther conditions: Empgliflozin Cardioprotective EffectView official trial listing → -
Not yet recruiting NCT NCT07828002
The GranStone Trial
Not yet reported, Not yet reported Martin Blomberg Jensen 100 participants Est. completion 2029-04 1 site Stand-aloneOther conditions: Paraffinoma, Granuloma, Foreign-BodyView official trial listing → -
Completed NCT NCT07832409
Cranberry Proanthocyanidins and Lactobacilli for Recurrent UTI Prevention in Type 2 Diabetes
Not yet reported National Institute of Endocrinology, Georgia 100 participants Est. completion 2026-03-18 1 siteType 2 diabetes Other conditions: Recurrent Urinary Tract InfectionsView official trial listing → -
Not yet recruiting NCT NCT07845630
A Study in Healthy People to Compare How 2 Different Formulations of Vicadrostat / Empagliflozin Tablets Are Taken up in the Body
Not yet reported Boehringer Ingelheim 36 participants Est. completion 2026-12-21 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT07848204
Continuous Ketone Monitoring in People With Type 1 Diabetes Using SGLT2 Inhibitors
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 24 participants Est. completion 2026-04-01 1 site Stand-aloneOther conditions: Diabetes, Type 1 Diabetes, T1DView official trial listing → -
Not yet recruiting NCT NCT07854808
Trial Without Borders IMPLEMENT-CKD: IMPLEMENTation of Evidence-Based SGLT2i to Reduce Global Burden of Cardiovascular and Chronic Kidney Disease
The University of Queensland 1390 participants Est. completion 2030-08-01 3 sitesCardiovascular disease Other conditions: Implementation Research, Kidney Disease, Chronic IllnessView official trial listing → -
Not yet recruiting NCT NCT07854990
Clinical Predictors and Therapeutic Gaps in CKM Syndrome Among Adults With Type 2 Diabetes
Assiut University 231 participants Est. completion 2028-07-10 1 siteType 2 diabetesMetabolic syndromeChronic kidney diseaseView official trial listing → -
Not yet recruiting NCT NCT07857772
This Will be a Randomized Comparison of the Proteomic Effects of Vicadrostat/Empagliflozin Versus Empagliflozin and Versus Empagliflozin/Spironolactone in Heart Failure Patients With Preserved Ejection Fraction
Not yet reported Baim Institute for Clinical Research 200 participants Est. completion 2028-09Heart failureView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Empagliflozin, Synjardy, JARDIANCE, Empagliflozin 10 MG, SGLT2 inhibitor, Empagliflozin 25 MG, Sodium-glucose cotransporter-2 (SGLT2) inhibitors, SGLT2i
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
