About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Ecnoglutide

Company: Hangzhou Sciwind Biosciences Co., Ltd.
Mechanism: Mechanism not yet reported
Route: Route not yet reported
Recruiting trials: 5 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

5 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026

Trial details

Recruiting NCT NCT07243171

A Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Ecnoglutide Tablets in Chinese Participants With Overweight or Obesity

Not yet reported, Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 84 participants Est. completion 2027-04-28 1 site Stand-alone

Other conditions: Overweight and/or Obesity, Weight Management
View official trial listing →
Recruiting NCT NCT07387094

A Study of XW003 in Obese Participants With Obstructive Sleep Apnea But Not Receive Positive Airway Pressure Therapy

Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 140 participants Est. completion 2027-12-16 1 site

Obstructive sleep apnea Other conditions: Obesity
View official trial listing →
Recruiting NCT NCT07434050

A Study of XW003 in Obese Participants With Obstructive Sleep Apnea Receiving Positive Airway Pressure Therapy

Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 140 participants Est. completion 2028-06-19 1 site

Obstructive sleep apnea Other conditions: Obesity
View official trial listing →
Recruiting NCT NCT07628127

A Trial of Oral VRB-103 Alone or in Combination With Oral Ecnoglutide (VRB-101) in Participants With Obesity or Overweight

Not yet reported Verdiva Bio Dev Limited 336 participants Est. completion 2028-03 1 site

Other conditions: Obesity, Overweight
View official trial listing →
Recruiting NCT NCT07734311

A Study of Econoglutide Injection in Obese Participants With Knee Osteoarthritis (KOA)

Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 360 participants Est. completion 2028-06-30 1 site Stand-alone

Osteoarthritis Other conditions: Obesity
View official trial listing →
Completed NCT NCT05184322

XW004 To Evaluate the Safety, Tolerability, PK, and PD of Oral Ecnoglutide Tablet in Healthy Adults

Not yet reported Sciwind Biosciences APAC CO Pty. Ltd. 87 participants Est. completion 2025-03-25 1 site Stand-alone

Type 2 diabetes Other conditions: Obesity
View official trial listing →
Completed NCT NCT05680129

A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Dulaglutide in Participants With T2DM

Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 623 participants Est. completion 2024-10-12 1 site Stand-alone

Type 2 diabetes
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Completed NCT NCT05680155

A Phase 3 Study to Evaluate the Efficacy of XW003 Compared With Placebo in T2DM Patients

Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 211 participants Est. completion 2024-10-12 1 site Stand-alone

Type 2 diabetes
View official trial listing →
Completed NCT NCT05813795

A Phase 3 Study to Evaluate the Efficacy of XW003 in Adults With Overweight or Obesity

Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 664 participants Est. completion 2024-10-10 1 site Stand-alone

Other conditions: Weight Management
View official trial listing →
Completed NCT NCT06335134

A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin

Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 57 participants Est. completion 2024-06-28 1 site

Other conditions: Healthy Volunteers
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Active, not recruiting NCT NCT07073417

A Study to Compare XW003 Injection and Semaglutide Injection in Chinese Adults With Obesity (SLIMMER-UP-SWITCH)

Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 163 participants Est. completion 2027-08-23 1 site

Other conditions: Obesity, Weight Management
View official trial listing →
Completed NCT NCT07143227

A Study of XW003 Injection in Chinese Adolescents With Obesity

Not yet reported Hangzhou Sciwind Biosciences Co., Ltd. 48 participants Est. completion 2026-04-18 1 site

Other conditions: Obese Adolescents, Obesity
View official trial listing →
Completed NCT NCT07281937

A Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

Not yet reported Verdiva Bio Dev Limited 206 participants Est. completion 2026-07-23 22 sites

Other conditions: Obesity, Overweight
View official trial listing →
Active, not recruiting NCT NCT07553299

A Study of Weekly Oral Dose of Ecnoglutide (VRB-101) for Weight Maintenance in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities

Not yet reported Verdiva Bio Dev Limited 120 participants Est. completion 2026-12-31 20 sites

Other conditions: Obesity, Overweight, Weight Maintenance
View official trial listing →

Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

ClinicalTrials.gov — NCT05680155

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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.