About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Donepezil Hydrochloride
- Company
- Duke University
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 15 recruiting
Efficacy results: Not yet reported
15 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 22, 2026
Find a Clinical Trial Near Me
See recruiting studies for Donepezil Hydrochloride and check eligibility with the study team.
Trial details
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Recruiting NCT NCT03810794
Clinical Evaluation on the Therapeutic Effect of Acupuncture Treatment for Alzheimer's Disease
Not yet reported Jian Pei,MD 180 participants Est. completion 2026-12-30 3 sites Stand-aloneOther conditions: Alzheimer Disease, Cognitive ImpairmentView official trial listing → -
Recruiting NCT NCT04661280
Donepezil Versus Non-drug Treatment in Alzheimer's Disease.
Not yet reported Assistance Publique - Hôpitaux de Paris 240 participants Est. completion 2026-08 1 site Stand-aloneOther conditions: Alzheimer Disease, Early OnsetView official trial listing → -
Recruiting NCT NCT05042102
Donepezil and Cognitive Training for Alcohol Use Disorder (AUD)
Not yet reported VA Connecticut Healthcare System 160 participants Est. completion 2026-10-31 1 site Stand-aloneAlcohol use disorderView official trial listing → -
Recruiting NCT NCT05592678
δ in Dementia Clinical Trials
Not yet reported The University of Texas Health Science Center at San Antonio 200 participants Est. completion 2028-11-30 1 siteOther conditions: Alzheimer's Disease (AD), Dementia, Cognitive Decline, Mild Cognitivie Impairment (MCI)View official trial listing → -
Recruiting NCT NCT05801380
Monitoring Drug Efficacy in Patients with Alzheimer's Disease
University of the Philippines 60 participants Est. completion 2026-02-14 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Recruiting NCT NCT05976152
Effect of Butyphthalide on Cognitive Level Change After Cerebral Vascular Event-a Randomized Control Trial (Be-CLEVER)
Not yet reported Fudan University 3200 participants Est. completion 2026-12 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT06041789
Effect of Acetylcholinesterase Inhibitors on Bone Metabolism
Not yet reported Duke University 45 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: OsteoporosisView official trial listing → -
Recruiting NCT NCT06313866
the Clinical Effect of TCM Sniffing Therapy Combined With Electroacupuncture in PSCI
Not yet reported Hangzhou Medical College 220 participants Est. completion 2025-06-01 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Recruiting NCT NCT06417086
Clinical Evaluation of Acupuncture Treatment on Alzheimer's Disease in APOE e4 Carriers and Non-Carriers
Not yet reported ZhanYJ 176 participants Est. completion 2026-11-30 1 site Stand-aloneOther conditions: Alzheimer Disease, Cognitive ImpairmentView official trial listing → -
Recruiting NCT NCT06871839
The Clinical Study of Synaptic Plasticity-based Lencanumab for the Treatment of Early Alzheimer's Disease
Cuibai Wei，Clinical Professor 120 participants Est. completion 2026-12-31 1 siteOther conditions: Alzheimer's Disease, Lecanemab, Functional Magnetic Resonance ImagingView official trial listing → -
Recruiting NCT NCT07066826
Clinical Study to Evaluate the Efficacy and Safety of Huperzine A Controlled-Release Tablets in Patients With Mild-to-Moderate Dementia of the Alzheimer's Type
Not yet reported, Not yet reported Wanbangde Pharmaceutical Group Co., LTD 720 participants Est. completion 2028-08-15 1 siteOther conditions: Alzheimer DementiaView official trial listing → -
Recruiting NCT NCT07094438
Study Safety and Efficacy of Deep Brain Stimulation (DBS) and Cervical Deep Lymphoid-venous Anastomosis (LVA) in Alzheimer's Disease
Not yet reported Chinese PLA General Hospital 98 participants Est. completion 2027-07 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Recruiting NCT NCT07153848
An Observational Study on Lecanemab Treatment for Early Alzheimer's Disease
First Affiliated Hospital of Zhejiang University 400 participants Est. completion 2027-12-31 2 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Recruiting NCT NCT07208344
Intravenous Infusion of Umbilical Cord Blood as an Adjunctive Treatment for Alzheimer's Disease
Not yet reported Anhui Provincial Hospital 30 participants Est. completion 2026-06-30 1 site Stand-aloneOther conditions: Alzheimer Disease (AD)View official trial listing → -
Recruiting NCT NCT07604896
Evaluating the Efficacy and Safety of Lecanemab in Alzheimer's Disease Through Multi-omics Approachs
Not yet reported First Affiliated Hospital of Wenzhou Medical University 200 participants Est. completion 2028-12-31 1 siteOther conditions: Alzheimer s Disease, Alzheimer Dementia (AD), MCI-AD, Early Stage Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00000173
Memory Impairment Study (Mild Cognitive Impairment Study)
Not yet reported National Institute on Aging (NIA) Est. completion 2004-01 72 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00004807
Study of the Pathogenesis of Rett Syndrome
Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 120 participantsOther conditions: Rett SyndromeView official trial listing → -
Completed NCT NCT00006349
Donepezil and Vitamin E to Prevent Side Effects Caused By Radiation Therapy to the Head in Patients Receiving Treatment for Small Cell Lung Cancer
Not yet reported Alliance for Clinical Trials in Oncology 9 participants Est. completion 2007-01 15 sites Stand-aloneOther conditions: Cognitive/Functional Effects, Delirium, Depression, Lung Cancer, Radiation ToxicityView official trial listing → -
Completed NCT NCT00006399
Effects of Estrogen on Memory in Post-Menopausal Women and Patients With Alzheimer's Disease
Not yet reported National Center for Research Resources (NCRR) 45 participants Est. completion 2004-03 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00015132
Tiagabine, Sertraline, or Donepezil for the Treatment of Cocaine Dependence - 9
Not yet reported National Institute on Drug Abuse (NIDA) Est. completion 2000-11 1 siteOther conditions: Cocaine-Related DisordersView official trial listing → -
Completed NCT NCT00018278
Electrophysiologic Measures of Treatment Response in Alzheimer Disease
Not yet reported US Department of Veterans Affairs Est. completion 2001-09 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00030979
Donepezil to Treat Dementia in Parkinson's Disease
Not yet reported National Institute of Neurological Disorders and Stroke (NINDS) 28 participants Est. completion 2005-03 1 siteOther conditions: Parkinson DiseaseView official trial listing → -
Status unknown NCT NCT00031018
Prevention of Cognitive Decline in Alzheimer's Disease by Ingested Interferon Alpha
Not yet reported National Center for Research Resources (NCRR) 1 siteOther conditions: Memory Disorders, Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00035204
A Study of the Effects on Sleep, Attention, and Gastrointestinal Tolerance of Galantamine and Donepezil in Patients With Alzheimer's Disease
Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 63 participants Est. completion 2003-05Other conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00042172
Treatment for Early Memory Loss
Not yet reported University of Iowa 40 participants Est. completion 2004-09 1 siteOther conditions: Cognition Disorders, Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00043589
Memory and Mental Health in Aging
Not yet reported Stanford University 200 participants Est. completion 2007-12 1 siteOther conditions: Memory DisordersView official trial listing → -
Completed NCT NCT00047697
Donepezil HCl & Cognitive Deficits in Autism
Not yet reported University of Pittsburgh 34 participants Est. completion 2006-08 1 site Stand-aloneOther conditions: Autistic DisorderView official trial listing → -
Withdrawn NCT NCT00062972
Improving Memory in Patients With Multiple Sclerosis
Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Est. completion 2002-08 1 siteOther conditions: Multiple SclerosisView official trial listing → -
Status unknown NCT NCT00069550
Independent Studies of Dextromethorphan and of Donepezil Hydrochloride for Rett Syndrome
Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 90 participants Est. completion 2008-06 1 siteOther conditions: Rett SyndromeView official trial listing → -
Completed NCT NCT00070161
Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor
Not yet reported Wake Forest University Health Sciences 68 participants Est. completion 2012-08-01 4 sitesOther conditions: Brain and Central Nervous System Tumors, Radiation ToxicityView official trial listing → -
Completed NCT NCT00096473
Efficacy and Safety of Aricept in the Treatment of Severe Alzheimer's Disease
Not yet reported Eisai Inc. 229 participants Est. completion 2005-09 42 sitesOther conditions: Alzheimer's Disease, DementiaView official trial listing → -
Completed NCT NCT00103948
The Efficacy, Safety, And Tolerability Of Donepezil HCl (E2020) In Patients With CADASIL Who Have Cognitive Impairment
Not yet reported Eisai Limited 165 participants Est. completion 2007-02 4 sitesOther conditions: Cognitive ImpairmentView official trial listing → -
Completed NCT NCT00104273
Rasagiline 1 mg and 2 mg Added to Aricept 10 mg Daily in Patients With Mild to Moderate Alzheimer's Disease (AD)
Not yet reported Teva Branded Pharmaceutical Products R&D, Inc. 376 participants 58 sitesOther conditions: Dementia, Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT00139373
Study of the Distractibility Syndrome in Patients With Progressive Supranuclear Palsy
Not yet reported Groupe Hospitalier Pitie-Salpetriere 16 participants 1 siteOther conditions: Supranuclear Palsy, ProgressiveView official trial listing → -
Status unknown NCT NCT00142324
CALM-AD
Not yet reported Institute of Psychiatry, London 190 participants Est. completion 2005-12 8 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00151398
Study Evaluating Lecozotan SR in Mild to Moderate Alzheimer's Disease (AD)
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 229 participants Est. completion 2008-03-15 56 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00165659
A Multi-Center, Randomized, Double-Blind, Parallel Group Study With 3 Groups Receiving Placebo, 5 mg of E2020 and 10 mg of E2020
Not yet reported Eisai Limited 65 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00165724
Alzheimer's Disease Long-term Follow-up Study (ALF Study)
Not yet reported Eisai Korea Inc. 114 participants Est. completion 2006-12-31 7 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00165737
Donepezil Hydrochloride (E2020) in Dementia Associated With Cerebrovascular Disease
Not yet reported Eisai Inc. 974 participants Est. completion 2006-06 5 sitesOther conditions: Dementia, VascularView official trial listing → -
Terminated NCT NCT00165750
Correlation Between Regional Brain Volume and Response to Donepezil Treatment in AD Patients
Not yet reported Eisai Korea Inc. 40 participants Est. completion 2008-11 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00165763
Efficacy and Safety of Donepezil Hydrochloride (Aricept) in Vascular Dementia
Not yet reported Eisai Inc. 36 participants 2 sites Stand-aloneOther conditions: Vascular DementiaView official trial listing → -
Completed NCT NCT00165815
The Efficacy, Tolerability and Safety of Donepezil (Aricept) in Parkinson's Disease Patients With Dementia
Not yet reported Eisai Limited Est. completion 2005-07 4 sitesOther conditions: Dementia With Parkinson's DiseaseView official trial listing → -
Terminated NCT NCT00174382
Vaspect Study - An Open-Label Trial Of Donepezil in Vascular and Mixed Dementia
Not yet reported Pfizer 149 participants Est. completion 2008-04 30 sites Stand-aloneOther conditions: Dementia, Vascular, Dementia, MixedView official trial listing → -
Completed NCT NCT00177671
Antidepressant Medication Plus Donepezil for Treating Late-life Depression
Not yet reported University of Pittsburgh 220 participants Est. completion 2009-09 1 site Stand-aloneOther conditions: Depression, DementiaView official trial listing → -
Completed NCT NCT00182845
Donepezil in the Prevention of Post-Operative Cognitive Decline
Not yet reported Pfizer 30 participants Est. completion 2007-04 1 siteOther conditions: Postoperative Complications, DeliriumView official trial listing → -
Completed NCT NCT00182884
Donepezil in Preventing Delirium in Hospitalized Elderly
Not yet reported Indiana University Health 30 participants Est. completion 2007-04 1 siteOther conditions: Postoperative Complications, DeliriumView official trial listing → -
Completed NCT NCT00188812
Safety of Donepezil in Patients With Dementia Associated With Cerebrovascular Disease
Not yet reported University Health Network, Toronto Est. completion 2005-08 1 siteOther conditions: Dementia Associated With Cerebrovascular DiseaseView official trial listing → -
Status unknown NCT NCT00190021
Donepezil Treatment of Psychotic Symptoms in Dementia Patients
Not yet reported Beersheva Mental Health Center 80 participants 1 siteOther conditions: Dementia of Alzheimer TypeView official trial listing → -
Completed NCT NCT00196690
Donepezil in Chronic Poststroke Aphasia: a Randomized Controlled Trial
Not yet reported Gabinete Berthier y Martínez 30 participants Est. completion 2005-03 1 siteCardiovascular disease Other conditions: AphasiaView official trial listing → -
Terminated NCT NCT00206947
The CAMPUS Project: Cholinergic Augmentation of Cognitive Deficits in Schizophrenia
Not yet reported Birte Glenthoj 50 participants Est. completion 2005-01 4 sitesOther conditions: SchizophreniaView official trial listing → -
Completed NCT NCT00220584
An Open-Label Trial of Donepezil in Fragile X Syndrome
Not yet reported Stanford University 10 participants Est. completion 2009-07 1 site Stand-aloneOther conditions: Fragile X SyndromeView official trial listing → -
Completed NCT NCT00220896
Prevention of Postoperative Delirium With Donepezil
Not yet reported Technical University of Munich 37 participants Est. completion 2009-03 1 siteOther conditions: Cognitively Normal Elderly IndividualsView official trial listing → -
Completed NCT NCT00227994
Acetylcholinesterase Inhibitors to Improve Cognitive Function and Overall Rehabilitation After a Stroke
Not yet reported University of Pittsburgh 40 participants Est. completion 2005-03 1 site Stand-aloneOther conditions: Cerebrovascular AccidentView official trial listing → -
Completed NCT NCT00230568
EARTH 413: A Study of Aricept in Hispanic Patients With Mild to Moderate Alzheimer's Disease (AD)
Not yet reported Eisai Inc. 100 participants Est. completion 2007-12 35 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00234637
Rivastigmine Monotherapy and Combination Therapy With Memantine in Patients With Moderately Severe Alzheimer's Disease Who Failed to Benefit From Previous Cholinesterase Inhibitor Treatment
Not yet reported Novartis 204 participants Est. completion 2005-06 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00267163
Brain Imaging and Mental Disorders of Aging Intervention
Not yet reported National Institute on Aging (NIA) 64 participants Est. completion 2007-07 1 site Stand-aloneOther conditions: Cognition DisordersView official trial listing → -
Completed NCT NCT00291421
A Survey Study of the Treatment and Outcome Management in Patients Diagnosed With Alzheimer's Disease
Janssen Pharmaceutica N.V., Belgium 2360 participants Est. completion 2006-05Other conditions: Alzheimer Disease, Dementia, Nervous System Diseases, Mental Disorders, Brain DiseasesView official trial listing → -
Completed NCT NCT00293176
The Evaluation of the Efficacy and Safety of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment (MCI)
Not yet reported Eisai Inc. 821 participants Est. completion 2007-03 54 sites Stand-aloneOther conditions: Memory LossView official trial listing → -
Completed NCT NCT00315367
A fMRI(Functional Magnetic Resonance Imaging) Research Study to Learn More About Multiple Sclerosis and Individuals Potentially Experiencing Memory Difficulties
Not yet reported Neurognostics 26 participants Est. completion 2007-10 1 siteOther conditions: Relapsing-Remitting Multiple SclerosisView official trial listing → -
Completed NCT NCT00348192
SB-742457 And Donepezil In Alzheimer's Disease
Not yet reported GlaxoSmithKline 200 participants 26 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00348309
Rosiglitazone (Extended Release Tablets) As Adjunctive Therapy For Subjects With Mild To Moderate Alzheimer's Disease
Not yet reported GlaxoSmithKline 1496 participants Est. completion 2009-01-28 249 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT00352664
The Effect of Donepezil on Sedation and Other Symptoms
Not yet reported M.D. Anderson Cancer Center 27 participants Est. completion 2007-07 1 siteOther conditions: Advanced CancerView official trial listing → -
Terminated NCT NCT00369603
Functional Brain Imaging of Medication Treatment Response in Mild Alzheimer's Disease Patients
Not yet reported Duke University 4 participants Est. completion 2007-11 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00369785
Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors
Not yet reported Wake Forest University Health Sciences 198 participants Est. completion 2012-07-01 16 sites Stand-aloneOther conditions: Brain Tumors, Metastatic DiseaseView official trial listing → -
Completed NCT NCT00381381
The Clinical Response of Choline Acetyltransferase and Apolipoprotein Epsilon Gene Polymorphisms to Donepezil in Alzheimer's Disease
Not yet reported Eisai Korea Inc. 199 participants Est. completion 2008-12-31 15 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00384423
Short Term Effects of PRX-03140 in Patients With Mild Alzheimer's Disease Being Treated With Aricept
Not yet reported Epix Pharmaceuticals, Inc. 80 participants 17 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00403520
Hippocampus Study: Comparative Effect of Donepezil 10mg/d and Placebo on Clinical and Radiological Markers
Not yet reported Eisai Inc. 240 participants Est. completion 2010-08 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00408525
Donepezil and Brain Activity Patterns in Those at Risk For Alzheimer's Disease
Not yet reported Vanderbilt University 41 participants Est. completion 2012-08-24 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00423228
Efficacy Study of a ZT-1 Implant in Patients Suffering From Alzheimer's Disease
Not yet reported Debiopharm International SA 228 participants Est. completion 2009-04 28 sites Stand-aloneOther conditions: Moderate Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00428090
Rosiglitazone (Extended Release Tablets) As Monotherapy In Subjects With Mild To Moderate Alzheimer's Disease
Not yet reported GlaxoSmithKline 862 participants Est. completion 2008-09-05 138 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00428389
Safety of Switching From Donepezil to Rivastigmine Patch in Patients With Probable Alzheimer's Disease
Not yet reported Novartis 262 participants Est. completion 2008-02 23 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00443014
The Dementia Study in Northern Norway
Not yet reported University Hospital of North Norway 187 participants Est. completion 2009-06 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00452868
Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
Not yet reported Wake Forest University Health Sciences 14 participants Est. completion 2010-02 2 sites Stand-aloneOther conditions: Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Long-term Effects Secondary to Cancer Therapy in Children, Neurotoxicity, Psychosocial Effects of Cancer and Its Treatment, Radiation ToxicityView official trial listing → -
Status unknown NCT NCT00457769
Aricept to Improve Functional Tasks in Vascular Dementia
Not yet reported Kessler Foundation 18 participants Est. completion 2021-12 1 site Stand-aloneCardiovascular disease Other conditions: Vascular Dementia, Memory DeficitsView official trial listing → -
Status unknown NCT NCT00465283
Donepezil Double Blind Trial for ECT Memory Disfunction
Not yet reported BeerYaakov Mental Health Center 40 participants Est. completion 2010-01 1 siteOther conditions: Schizophrenia, Schizoaffective Disorder, Schizophreniform DisorderView official trial listing → -
Completed NCT NCT00467389
Use of Donepezil for Treatment of Cocaine Dependence
Not yet reported US Department of Veterans Affairs 12 participants Est. completion 2008-09 1 site Stand-aloneOther conditions: Cocaine Abuse and DependenceView official trial listing → -
Completed NCT NCT00467766
Combining a Caregiver Intervention With Aricept Treatment for Mild to Moderate Alzheimer's Disease
Not yet reported Pfizer 300 participants Est. completion 2003-06 3 sitesOther conditions: Alzheimer Disease, CaregiversView official trial listing → -
Completed NCT NCT00477659
Neural Correlates In Mild Alzheimer's Disease
Not yet reported Eisai Inc. 14 participants Est. completion 2008-08-15 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00478205
Comparison of 23 mg Donepezil Sustained Release (SR) to 10 mg Donepezil Immediate Release (IR) in Patients With Moderate to Severe Alzheimer's Disease
Not yet reported Eisai Inc. 1467 participants 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00480870
The Effect of Anticholinesterase Drugs on Sleep in Alzheimer's Disease Patients
Not yet reported Associacao Fundo de Incentivo a Psicofarmcologia 65 participants Est. completion 2005-01 1 site Stand-aloneOther conditions: Alzheimer Disease, Sleep Apnea, ObstructiveView official trial listing → -
Completed NCT NCT00482001
Impact of Cholinesterase Inhibitors on Driving Ability in Healthy Older Adults
Not yet reported Sunnybrook Health Sciences Centre 22 participants Est. completion 2008-08 2 sites Stand-aloneOther conditions: Mental Health, GeriatricsView official trial listing → -
Completed NCT NCT00483028
A Randomized, Placebo-Controlled Trial to Examine the Efficacy of Oral Donepezil in Subjects With MCI
Not yet reported Pfizer 38 participants Est. completion 2007-01 2 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00501111
Proof of Concept Study of Cognitive Improvement in Patients With Alzheimer's Disease
Not yet reported AstraZeneca 659 participants Est. completion 2008-08 70 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00505167
Memantine Versus Donepezil in Early Stages of Alzheimer's Disease
Not yet reported Hospital Miguel Servet 64 participants Est. completion 2008-12 3 sitesOther conditions: Dementia, Alzheimer TypeView official trial listing → -
Completed NCT NCT00519298
Study Evaluating Effects of SAM-531 on Sleep Electroencephalogram (EEG) and Quantitative Wake EEG in Healthy Subjects
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 25 participants Est. completion 2008-03 1 siteOther conditions: Healthy, AdultView official trial listing → -
Status unknown NCT NCT00530478
Effect of Donepezil on the Reorganization of Cognitive Neural Network in Patients With Post-Stroke Cognitive Impairment
Not yet reported Samsung Medical Center 1 siteCardiovascular diseaseView official trial listing → -
Completed NCT NCT00533065
Effects of Donepezil on Deficits Associated With Age-Related Decrease of Growth Hormone
Not yet reported Ludwig Boltzmann Gesellschaft 80 participants Est. completion 2009-07 1 siteOther conditions: ElderlyView official trial listing → -
Completed NCT NCT00543855
A Double-blind Study of E2020 (Donepezil Hydrochloride) in Patients With Dementia With Lewy Bodies (DLB) (Study E2020-J081-431)
Not yet reported Eisai Co., Ltd. 167 participants Est. completion 2010-02 43 sites Stand-aloneOther conditions: Dementia With Lewy Bodies (DLB)View official trial listing → -
Terminated NCT NCT00548145
The Clinical Study of Pitavastatin Treatment for Group of Mild to Moderate Alzheimer's Disease
Not yet reported Osaka University 38 participants Est. completion 2012-03 1 siteOther conditions: Alzheimer Disease, HypercholesterolemiaView official trial listing → -
Completed NCT NCT00551161
Magnetic Resonance Spectroscopy Study of Memantine in Alzheimer's Disease
Not yet reported Northwell Health 12 participants Est. completion 2011-12 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00566501
Open-Label Extension Study of 23 mg Donepezil SR in Participants With Moderate to Severe Alzheimer's Disease
Not yet reported Eisai Inc. 915 participants Est. completion 2010-04-01 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00570128
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome
Not yet reported Eisai Inc. 129 participants Est. completion 2008-09-05 31 sitesOther conditions: Down SyndromeView official trial listing → -
Completed NCT NCT00571064
The Effectiveness And Safety Of Donepezil Hydrochloride (E2020) In Subjects With Mild To Severe Alzheimer's Disease Residing In An Assisted Living Facility
Not yet reported Eisai Inc. 97 participants Est. completion 2009-04-22 36 sites Stand-aloneOther conditions: Mild to Severe Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00586196
Supporting the Health of Adults Undergoing Orthopedic Surgery During the Recovery Period
Not yet reported Beth Israel Deaconess Medical Center 16 participants Est. completion 2013-02 1 siteOther conditions: DeliriumView official trial listing → -
Completed NCT NCT00594633
Adjunctive Donepezil Therapy and Genetic Risk Factors of Cognitive Dysfunction in Brain Tumor Survivors
Not yet reported Memorial Sloan Kettering Cancer Center 25 participants Est. completion 2016-01 1 site Stand-aloneOther conditions: Brain Tumor, Brain Cancer, Cns Cancer, Cognitive DysfunctionView official trial listing → -
Completed NCT NCT00598650
A Long-term, Extension Study of E2020 in Patients With Dementia With Lewy Bodies
Not yet reported Eisai Co., Ltd. 160 participants Est. completion 2011-03Other conditions: Dementia With Lewy Bodies (DLB)View official trial listing → -
Terminated NCT NCT00602680
Effect on Cognitive Performance and Safety/Tolerability of SSR180711C in Mild Alzheimer's Disease
Not yet reported Sanofi 1 participants Est. completion 2008-07 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT00619983
Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic Neuropathy
Not yet reported Wake Forest University 22 participants Est. completion 2013-05 2 sitesOther conditions: Diabetic Neuropathic Pain, Chronic Low Back PainView official trial listing → -
Completed NCT NCT00630851
A Study of the Efficacy and Safety of Aricept in Patients With Severe Alzheimer's Disease Who Are Living in Skilled Nursing Homes
Not yet reported Pfizer 249 participants Est. completion 2004-10 53 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Terminated NCT NCT00672945
A Study of PRX-03140 in Subjects With Alzheimer's Disease Receiving a Stable Dose of Donepezil
Not yet reported Epix Pharmaceuticals, Inc. 420 participants 38 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT00675025
Evaluating The Safety Of Donepezil Hydrochloride (Aricept) For Up To 1 Year In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome - Follow-Up To A 10-Week, Double-Blind, Placebo-Controlled Trial
Not yet reported Eisai Inc. 117 participants Est. completion 2008-12-15 31 sites Stand-aloneOther conditions: Down SyndromeView official trial listing → -
Completed NCT NCT00688376
Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairment Following Cancer Treatment
Not yet reported Eisai Inc. 72 participants Est. completion 2009-05-26 31 sites Stand-aloneOther conditions: Attention ImpairmentView official trial listing → -
Terminated NCT NCT00693004
Study of PRX-03140 Monotherapy in Subjects With Alzheimer's Disease
Not yet reported Epix Pharmaceuticals, Inc. 236 participants 33 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00695136
The Effect of Donepezil (Aricept(Registered Trademark)) on REM Sleep in Children With Autism
Not yet reported, Not yet reported National Institute of Mental Health (NIMH) 17 participants Est. completion 2011-01 1 site Stand-aloneOther conditions: Autism, Cognition DisorderView official trial listing → -
Completed NCT NCT00702780
Progression Delaying Effect of Escitalopram in Alzheimer's Disease
Not yet reported Seoul National University Hospital 74 participants Est. completion 2011-09 4 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT00704782
Study of Combination Therapy With Dimebon and Donepezil (Aricept) in Patients With Alzheimer's Disease
Not yet reported Medivation, Inc. 50 participants Est. completion 2010-08 4 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00708552
Study of SB-742457 or Donepezil Versus Placebo in Subjects With Mild-to-moderate Alzheimer's Disease
Not yet reported GlaxoSmithKline 576 participants Est. completion 2010-03-09 72 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00710684
A Study of SB-742457, Added to Donepezil for the Treatment of Mild-to-moderate Alzheimer's Disease
Not yet reported GlaxoSmithKline 682 participants Est. completion 2010-11-16 102 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Withdrawn NCT NCT00711204
Evaluating The Impact Of Donepezil Hydrochloride (Aricept) On Behavioral And Psychological Symptoms In Patients With Severe Alzheimer's Disease
Not yet reported Eisai Inc. 1 siteOther conditions: Severe Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT00713765
Pharmacokinetic Interaction Between AZD3480 and Donepezil
Not yet reported AstraZeneca 33 participants Est. completion 2008-12 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00750529
Alzheimer and Sleep
Not yet reported University Hospital, Clermont-Ferrand 15 participants Est. completion 2013-09 2 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT00754013
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10
Not yet reported Eisai Inc. 9 participants Est. completion 2008-12 2 sitesOther conditions: Down Syndrome, Cognitive DysfunctionView official trial listing → -
Terminated NCT NCT00754052
Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17
Not yet reported Eisai Inc. 8 participants Est. completion 2008-12 2 sitesOther conditions: Down Syndrome, Cognitive DysfunctionView official trial listing → -
Completed NCT NCT00766363
Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Alzheimer's Disease
Not yet reported FORUM Pharmaceuticals Inc 49 participants Est. completion 2009-03 4 sites Stand-aloneOther conditions: Alzheimer's Disease, Central Nervous System DiseasesView official trial listing → -
Completed NCT NCT00768261
Corticolimbic Degeneration and Treatment of Dementia
Not yet reported Washington University School of Medicine 39 participants Est. completion 2009-10Other conditions: DementiaView official trial listing → -
Completed NCT NCT00776347
Donepezil Therapy and Changes of Symptoms and Glucose Metabolism in Patients With Dementia With Lewy Bodies (DLB)
Not yet reported Osaka University 24 participants Est. completion 2015-02 1 site Stand-aloneOther conditions: Dementia With Lewy Bodies (DLB)View official trial listing → -
Completed NCT NCT00777608
A Study to Test the Performance of the CogState Computerized Neuropsychological Battery in Patients With Alzheimer's Disease (0000-086)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 106 participants Est. completion 2010-04 Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00800553
fMRI-behavioral Study of Cholinergic Augmentation With Donepezil in Healthy Sleep Deprived Adults
Not yet reported Duke-NUS Graduate Medical School 43 participants Est. completion 2007-05 1 site Stand-aloneOther conditions: Sleep DeprivationView official trial listing → -
Completed NCT NCT00805792
Mayo Acute Stroke Trial for Enhancing Recovery
Not yet reported Mayo Clinic 33 participants Est. completion 2010-09 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00829374
Safety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil
Not yet reported Medivation, Inc. 1003 participants Est. completion 2011-12 101 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00829816
Safety and Tolerability of Dimebon in Patients on Memantine, and Memantine Plus Donepezil
Not yet reported Medivation, Inc. 46 participants Est. completion 2010-08 4 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00842816
Preliminary Efficacy and Safety Study of ST101 Plus Aricept in Alzheimer's Disease
Not yet reported Sonexa Therapeutics, Inc. 210 participants Est. completion 2011-05 30 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT00843115
Observational Study Of Donepezil In Routine Clinical Practice
Pfizer 370 participants Est. completion 2008-04Other conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT00866060
Donepezil and Memantine in Moderate to Severe Alzheimer's Disease
Not yet reported King's College London 800 participants Est. completion 2013-06 1 siteOther conditions: Moderate to Severe Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT00868010
Enhancing Rehabilitation After Stroke
Not yet reported Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 200 participants Est. completion 2013-11 2 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Terminated NCT NCT00874939
A Study to Evaluate the Effects of MK-0249 and an Alzheimer's Disease Medication on Cognitive Function in Adults With Alzheimer's Disease (MK-0249-023)
Not yet reported Merck Sharp & Dohme LLC 4 participants Est. completion 2009-04-20 Stand-aloneOther conditions: Alzheimer's Disease, DementiaView official trial listing → -
Completed NCT NCT00880412
A Study to Determine the Clinical Safety/Tolerability and Exploratory Efficacy of EHT 0202 as Adjunctive Therapy to Acetylcholinesterase Inhibitor in Mild to Moderate Alzheimer's Disease
Not yet reported Exonhit 197 participants Est. completion 2009-08 22 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00884507
A Study of RO5313534 as Add-on to Donepezil Treatment in Patients With Mild to Moderate Alzheimer's Disease
Not yet reported Hoffmann-La Roche 389 participants Est. completion 2010-11 67 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00887601
BOLD Functional Magnetic Resonance Imaging (fMRI) and Cerebral Blood Flow Measurements as Biomarkers for Cognition Enhancing Drugs (3134-006)
Not yet reported Merck Sharp & Dohme LLC 32 participants Est. completion 2008-05 Stand-aloneOther conditions: DementiaView official trial listing → -
Completed NCT NCT00889603
Non-Interventional Study With Aricept® Evess
Pfizer 370 participants Est. completion 2010-03 12 sitesOther conditions: Alzheimer's Disease, Vascular DementiaView official trial listing → -
Terminated NCT NCT00895895
Study Comparing 3 Dosage Levels Of SAM-531 In Outpatients With Mild To Moderate Alzheimer Disease
Not yet reported Pfizer 526 participants Est. completion 2011-05 96 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT00911807
Comparative Study to Test Safety and Efficacy of Neurotrophic and Cholinergic Treatment of Alzheimer's Disease
Not yet reported Ever Neuro Pharma GmbH 217 participants Est. completion 2008-04 3 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT00912457
Donepezil Treatment for Sleep Apnea Patients
Not yet reported Associacao Fundo de Incentivo a Psicofarmcologia 60 participants Est. completion 2009-12 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT00912808
Cholinergic Augmentation in Frequently Falling Subjects With Parkinson's Disease
Not yet reported Oregon Health and Science University 23 participants Est. completion 2009-02 Stand-aloneOther conditions: Parkinson's DiseaseView official trial listing → -
Completed NCT NCT00916383
Study in Elderly Alzheimer's Patients to Assess Skin Tolerability, Irritation With 3, 7-Day Applications of DTP-System
Not yet reported Teikoku Pharma USA, Inc. 49 participants Est. completion 2009-06 7 sites Stand-aloneOther conditions: Irritation/IrritantView official trial listing → -
Completed NCT NCT00934375
A 28-Week Open Label Extension Study Evaluating Safety and Tolerability of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment
Not yet reported Eisai Inc. 145 participants Est. completion 2007-09 49 sites Stand-aloneOther conditions: Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT00934531
Donepezil and the Risk of Falls in Seniors With Cognitive Impairment
Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 60 participants Est. completion 2019-01 1 site Stand-aloneOther conditions: Falls, Gait, Balance, Mild Cognitive Impairment (MCI)View official trial listing → -
Completed NCT NCT00948909
Efficacy and Safety Study for Subjects With Mild-to-Moderate Alzheimer's Disease
Not yet reported AbbVie (prior sponsor, Abbott) 274 participants Est. completion 2010-11 29 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00951834
Sunphenon EGCg (Epigallocatechin-Gallate) in the Early Stage of Alzheimer´s Disease
Not yet reported, Not yet reported Charite University, Berlin, Germany 21 participants Est. completion 2015-02 3 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT00959881
Study Evaluating The Coadministration of Begacestat And Donepezil
Not yet reported Wyeth is now a wholly owned subsidiary of Pfizer 47 participants Est. completion 2009-11 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT00967707
Population Pharmacokinetic-pharmacodynamic (PK-PD) Modeling of Co-administered Gabapentin in Neuropathic Pain
Not yet reported Uppsala University 30 participants Est. completion 2011-09 1 siteOther conditions: Post-traumatic Neuropathic PainView official trial listing → -
Completed NCT NCT00987220
Effect of Aricept on Biomarkers (Acetylcholine, sAPP Alpha) In Cerebrospinal Fluid
Pfizer 12 participants Est. completion 2010-02 1 siteOther conditions: Alzheimer's Disease, DementiaView official trial listing → -
Completed NCT NCT00988598
A Brief Study To Evaluate The Safety, Tolerability, And Blood Levels Of Multiple Doses Of PF-044467943 Or Placebo In Combination With Donepezil In Subjects With Mild To Moderate Alzheimer's Disease
Not yet reported Pfizer 15 participants Est. completion 2010-07-05 3 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT01014858
Multi-centre UK Study of the Acetylcholinesterase Inhibitor Donepezil in Early Dementia Associated With Parkinson's Disease
Not yet reported Newcastle-upon-Tyne Hospitals NHS Trust 64 participants Est. completion 2014-09 22 sites Stand-aloneOther conditions: Parkinson's DiseaseView official trial listing → -
Completed NCT NCT01018875
Efficacy and Safety Study of ABT-288 in Subjects With Mild-to-Moderate Alzheimer's Disease
Not yet reported AbbVie (prior sponsor, Abbott) 242 participants Est. completion 2011-02 21 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01019421
Lu AE58054 Added to Donepezil for the Treatment for Moderate Alzheimer's Disease
Not yet reported H. Lundbeck A/S 278 participants 51 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01023425
Clinical Trial of Donepezil Between the Naive Group and the Switching Group
Not yet reported Samsung Medical Center 72 participants Est. completion 2009-04 1 site Stand-aloneOther conditions: Alzheimer's Disease, DementiaView official trial listing → -
Completed NCT NCT01023867
Clinical Trial of Donepezil Between the Patients With Alzheimer's Disease and Mixed Dementia
Not yet reported Samsung Medical Center 88 participants Est. completion 2010-06 1 site Stand-aloneOther conditions: Alzheimer's Disease, DementiaView official trial listing → -
Completed NCT NCT01024660
The Effect of Cognitive Function as Measured by Repeated Cognitive Measures After 12 Weeks Treatment With Donepezil
Not yet reported AstraZeneca 155 participants Est. completion 2011-01 18 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT01028911
A Study to Evaluate the Safety, Tolerability, and Blood Levels of PF-03654746 in Subjects With Mild to Moderate Alzheimer's Disease
Not yet reported Pfizer 9 participants Est. completion 2010-05 2 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01039701
4 Week, Safety and Tolerability Study in Patients With Mild to Moderate Alzheimer's Disease
Not yet reported AstraZeneca 99 participants Est. completion 2010-07 12 sites Stand-aloneOther conditions: Mild to Moderate Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01042314
Drug-Drug Interaction Study With Aricept® (Donepezil)
Not yet reported Bristol-Myers Squibb 18 participants Est. completion 2010-04 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT01044342
A Healthy Volunteer Study to Evaluate Reversibility of Induced Impairment of Cognition
Not yet reported AstraZeneca 20 participants Est. completion 2010-04 1 siteOther conditions: CognitionView official trial listing → -
Completed NCT NCT01063556
Pharmacokinetics Study of Donepezil HCl in Subjects Receiving Haemodialysis.
Not yet reported Eisai Co., Ltd. 6 participants Est. completion 2010-03 1 site Stand-aloneOther conditions: End-Stage Renal DiseaseView official trial listing → -
Terminated NCT NCT01082965
Acute Effects Of Donepezil On Brain Perfusion And Memory In Subjects With Cognitive Impairment And Mild Alzheimer's Disease
Not yet reported Pfizer 18 participants Est. completion 2012-07 8 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01089582
Quality Of Life Assessment In Alzheimer's Disease (AD) Patients Receiving Aricept Tablets
Pfizer 628 participants Est. completion 2009-07 29 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT01097876
A Study To Evaluate The Safety, Tolerability And Plasma Drug Levels Of PF-04447943 When Administered With Donepezil To Healthy Volunteer Subjects
Not yet reported Pfizer 24 participants Est. completion 2010-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01098383
Treatment With Acetyl-Choline Esterase Inhibitors in Children With Autism Spectrum Disorders
Not yet reported Sheba Medical Center 84 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: AutismView official trial listing → -
Completed NCT NCT01120626
Randomized Controlled Study of Donepezil in Fragile X Syndrome
Not yet reported Stanford University 45 participants Est. completion 2013-12 1 siteOther conditions: Fragile X SyndromeView official trial listing → -
Terminated NCT NCT01125683
To Evaluate Effects of AZD1446, Placebo and Donepezil in Patients With Alzheimer's Disease
Not yet reported AstraZeneca 40 participants Est. completion 2011-03 7 sitesOther conditions: Alzheimer´s DiseaseView official trial listing → -
Completed NCT NCT01129596
Post-marketing Surveillance of Long-term Administration of Donepezil Hydrochloride -Investigation of the Clinical Condition and Safety in Patients With Alzheimer's Disease-
Eisai Co., Ltd. 10238 participants Est. completion 2016-06-23 722 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01137526
Efficacy and Safety Study of ABT-384 in Subjects With Mild-to-Moderate Alzheimer's Disease
Not yet reported AbbVie (prior sponsor, Abbott) 267 participants Est. completion 2011-07 30 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01146509
An Evaluation Of The Efficacy And Safety Of Donepezil Hydrochloride (E2020) In Migraine Prophylaxis
Not yet reported Eisai Inc. 89 participants Est. completion 2007-03 4 sites Stand-aloneOther conditions: Migraine HeadacheView official trial listing → -
Completed NCT NCT01181310
Placebo-Controlled Crossover Study to Evaluate Donepezil and MK-3134 for Reversal of Cognitive Impairment Associated With Scopolamine Administration (3134-005)(COMPLETED)
Not yet reported Merck Sharp & Dohme LLC 31 participants Est. completion 2007-10 Stand-aloneOther conditions: DementiaView official trial listing → -
Completed NCT NCT01191918
The Efficacy and Safety of AChE Inhibitor Donepezil As Adjunctive Treatment to Mood Stabilizers in Acute Mania
Not yet reported Shanghai Mental Health Center 40 participants Est. completion 2008-04 Stand-aloneOther conditions: Bipolar Disorder, ManiaView official trial listing → -
Completed NCT NCT01194336
Evaluation of Three Potential Central Nervous System (CNS) Pretreatments for Soman Exposure on Human Performance
U.S. Army Medical Research and Development Command 84 participants Est. completion 2012-10 1 siteOther conditions: Biomarkers, PharmacologicalView official trial listing → -
Completed NCT NCT01213355
Scopolamine Challenge Study
Not yet reported Pfizer 38 participants Est. completion 2011-08 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01245530
An Efficacy and Safety Study of INM-176 for the Treatment of Patients With Alzheimer Type Dementia
Not yet reported Whanin Pharmaceutical Company 280 participants Est. completion 2011-03 1 siteOther conditions: Alzheimer Type DementiaView official trial listing → -
Completed NCT NCT01249196
A Confirmatory Trial of SK-PC-B70M in Mild to Moderate Alzheimer's Disease
Not yet reported SK Chemicals Co., Ltd. 256 participants 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01250977
Effect of Donepezil on Smoking
Not yet reported Abramson Cancer Center at Penn Medicine 30 participants Est. completion 2011-12-06 1 site Stand-aloneOther conditions: SmokingView official trial listing → -
Completed NCT NCT01251718
Post-marketing Surveillance of Donepezil Hydrochloride -Investigation of the Clinical Safety and Effectiveness in Patients With Alzheimer's Disease
Eisai Co., Ltd. 894 participants Est. completion 2016-02-18 106 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT01255046
Study of STA-1 as an Add-on Treatment to Donepezil
Not yet reported Sinphar Pharmaceutical Co., Ltd 136 participants 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT01260922
10 mg Donepezil Hydrochloride Orally Disintegrating Tablets Under Fasting Conditions.
Not yet reported Teva Pharmaceuticals USA 26 participants Est. completion 2006-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01260948
10 mg Donepezil Hydrochloride Orally Disintegrating Tablets Under Non-Fasting Conditions
Not yet reported Teva Pharmaceuticals USA 26 participants Est. completion 2006-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01266525
Effect of Different Doses of SAR110894 on Cognition in Patients With Mild to Moderate Alzheimer's Disease on Donepezil
Not yet reported Sanofi 291 participants Est. completion 2013-01 82 sites Stand-aloneOther conditions: Dementia Alzheimer's TypeView official trial listing → -
Completed NCT NCT01276067
Bioequivalence Study of Donepezil Hydrochloride 10 mg Tablets Under Fasting Conditions
Not yet reported Ranbaxy Laboratories Limited 32 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01276080
Bioequivalence Study of Donepezil Hydrochloride 10 mg Tablets Under Fed Conditions
Not yet reported Ranbaxy Laboratories Limited 36 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01276353
A Study Versus E2020 10mg Followed by an Open-label Extension Phase to Explore the Safety of E2020 SR 23 mg in Japanese Subjects With Severe Alzheimer's Type Dementia
Not yet reported Eisai Inc. 45 participants Est. completion 2012-04 11 sites Stand-aloneOther conditions: Alzheimer's Type DementiaView official trial listing → -
Completed NCT NCT01278407
A Study of E2020 in Patients With Dementia With Lewy Bodies (DLB), Followed by a Long-term Extension Phase
Not yet reported Eisai Co., Ltd. 142 participants Est. completion 2013-04 56 sites Stand-aloneOther conditions: Dementia With Lewy Bodies (DLB)View official trial listing → -
Completed NCT NCT01297036
Pharmacokinetic Comparisons of Two Donepezil Formulations
Not yet reported Korea University Anam Hospital 22 participants Est. completion 2008-05 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT01327859
Safety, Tolerability, and Efficacy of Donepezil (Aricept) in Parkinson' s Disease (PD) Patients With Dementia
Not yet reported Eisai Inc. 357 participants Est. completion 2006-07 1 site Stand-aloneOther conditions: Parkinson's Disease, DementiaView official trial listing → -
Terminated NCT NCT01345864
Assessment Of The Effects Of Single Doses Of An Investigational Drug, Given Alone Or With Donepezil, On Scopolamine-Induced Changes In Memory And Learning In Healthy Adults
Not yet reported Pfizer 88 participants Est. completion 2011-08 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT01362686
Comparative Research of Alzheimer's Disease Drugs
Not yet reported Indiana University 200 participants Est. completion 2015-10 5 sites Stand-aloneOther conditions: Dementia, Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01379001
Assessment of Cholinergic and Cognitive Function Using Pharmacologic ASL-Perfusion MRI
Not yet reported Hebrew SeniorLife 60 participants Est. completion 2013-01 Stand-aloneOther conditions: Cholinergic FunctionView official trial listing → -
Completed NCT NCT01404169
A 24-weeks, Multi-center, Randomized, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Donepezil Hydrochloride in Chinese Subjects With Severe Alzheimer's Disease
Not yet reported Eisai Limited 260 participants Est. completion 2014-09 32 sites Stand-aloneOther conditions: Alzheimer's Type DementiaView official trial listing → -
Completed NCT NCT01406145
A Study of the Safety and Tolerability of ASP0777 in Subjects With Alzheimer's Disease (AD) Taking a Stable Dose of Donepezil
Not yet reported Astellas Pharma Inc 60 participants Est. completion 2011-11-04 2 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01409564
Cilostazol Augmentation Study in Dementia
Not yet reported Seoul National University Hospital 46 participants Est. completion 2013-07 1 site Stand-aloneOther conditions: Alzheimer's DementiaView official trial listing → -
Completed NCT NCT01419340
Bioequivalence Study of Torrent Pharmaceutical Limited's Donepezil Hydrochloride Tablets Under Fasting Conditions
Not yet reported Torrent Pharmaceuticals Limited 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01419366
Bioequivalence Study of Torrent Pharmaceutical Limited's Donepezil Hydrochloride Tablets Under Fed Conditions
Not yet reported Torrent Pharmaceuticals Limited 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01428362
VI-1121 for the Treatment Alzheimer's Disease
Not yet reported VIVUS LLC 61 participants Est. completion 2013-08 11 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01439230
Donepezil 10 mg Tablets Under Fasting Conditions
Not yet reported Teva Pharmaceuticals USA 36 participants Est. completion 2007-08 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01439243
Donepezil 10 mg Tablets Under Fed Conditions
Not yet reported Teva Pharmaceuticals USA 26 participants Est. completion 2007-07 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Withdrawn NCT NCT01442766
Donepezil Trial for Motor Recovery in Acute Stroke
Not yet reported, Not yet reported Imperial College London Est. completion 2014-05 1 site Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT01450839
E2022 Patch Formulation Multiple Dose Study
Not yet reported Eisai Co., Ltd. 16 participants Est. completion 2012-02 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01451749
Efficacy and Safety Study of Shenwu Capsule
Not yet reported North China Pharmaceutical Group Corporation 324 participants Est. completion 2010-05 1 site Stand-aloneOther conditions: Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT01461174
Effects of Donepezil and Memantine on Cognitive Functions After a Sleep Deprivation Challenge in Healthy Volunteers
Not yet reported Qualissima 36 participants Est. completion 2014-11 2 sites Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01466088
Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)
Not yet reported Targacept Inc. 386 participants Est. completion 2014-05 33 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01466270
Study of Donepezil in Female Breast Cancer Survivors With Cognitive Dysfunction
Not yet reported Wake Forest University Health Sciences 62 participants Est. completion 2013-10-01 Stand-aloneOther conditions: Anxiety Disorder, Breast Cancer, Cognition Disorders, Depression, Fatigue, Sleep DisordersView official trial listing → -
Completed NCT NCT01478633
Evaluation of Efficacy and Safety of Galantamine in Patients With Dementia of Alzheimer's Type Who Failed to Benefit From Donepezil
Not yet reported Janssen Pharmaceutical K.K. 102 participants Est. completion 2013-06 11 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01485185
Gabapentin and Donepezil Combination on Experimental Human Pain Models
Not yet reported GlaxoSmithKline 48 participants Est. completion 2012-07-03 1 site Stand-aloneOther conditions: Pain, NeuropathicView official trial listing → -
Completed NCT NCT01487395
Prediction of Cognitive Properties of New Drug Candidates for Neurodegenerative Diseases in Early Clinical Development
Not yet reported University Hospital, Lille 30 participants Est. completion 2013-12 3 sitesOther conditions: Alzheimer Disease, BatteryView official trial listing → -
Status unknown NCT NCT01490567
A Double-blind, Placebo-controlled Trial of Donepezil Adjunctive Treatment for Cognitive Impairment in Schizophrenia
Not yet reported Central South University 80 participants Est. completion 2012-06 1 siteOther conditions: Impaired Cognition, SchizophreniaView official trial listing → -
Completed NCT NCT01495195
Combined Donepezil and Selegiline Effects on Cocaine-Reinforced Behavior
Not yet reported Midwest Biomedical Research 12 participants Est. completion 2013-05 1 site Stand-aloneOther conditions: Cocaine Use DisordersView official trial listing → -
Completed NCT NCT01504503
Bioequivalence Study for Donepezil Hydrochloride 10 mg Tablets Under Fasting Condition
Not yet reported Dr. Reddy's Laboratories Limited 26 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01504516
Bioequivalence Study for Donepezil Hydrochloride Tablets 10 mg Under Fed Condition
Not yet reported Dr. Reddy's Laboratories Limited 25 participants Est. completion 2009-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01506739
A Bioequivalence Study of Film-coated Tablet and Dry Syrup 1% Form for E2020 in Healthy Japanese Adult Males
Not yet reported Eisai Co., Ltd. 12 participants Est. completion 2011-05 1 siteOther conditions: Healthy AdultView official trial listing → -
Completed NCT NCT01506752
A Bioequivalence Study Comparing Improved Versus Current Orally Disintegrating E2020 10 mg Tablet in Healthy Japanese Adult Males
Not yet reported Eisai Co., Ltd. 20 participants Est. completion 2011-09 1 siteOther conditions: Healthy AdultView official trial listing → -
Completed NCT NCT01521117
The Effect of Donepezil on Gait and Balance in Parkinson's Disease
Not yet reported Oregon Health and Science University 21 participants Est. completion 2012-07 1 site Stand-aloneOther conditions: Parkinson's DiseaseView official trial listing → -
Completed NCT NCT01527916
Evaluate the Efficacy and Safety of ABT-126 in Subjects With Mild to Moderate Alzheimer's Disease
Not yet reported AbbVie (prior sponsor, Abbott) 438 participants Est. completion 2013-11 33 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01529619
Efficacy, Safety and Tolerability of Rivastigmine Patch in Patients With Mild to Moderate Alzheimer's Disease Switched From Cholinesterase Inhibitors
Not yet reported Novartis Pharmaceuticals 52 participants Est. completion 2013-12 11 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01539031
Compare the Efficacy and Safety of Donepezil Hydrochloride 23 mg Treatment With Continuation of Donepezil Hydrochloride 10 mg Treatment in Japanese Subjects With Severe Alzheimer's Disease
Not yet reported Eisai Co., Ltd. 351 participants Est. completion 2015-03 54 sites Stand-aloneOther conditions: Alzheimer's Type DementiaView official trial listing → -
Completed NCT NCT01584076
Treatment of Residual Amblyopia With Donepezil
Not yet reported Boston Children's Hospital 18 participants Est. completion 2021-01 3 sites Stand-aloneOther conditions: AmblyopiaView official trial listing → -
Terminated NCT NCT01633593
Treatment of Delirium in the Elderly With Donepezil: a Double-blind, Randomized, Placebo-controlled Clinical Trial
Not yet reported University of Sao Paulo 19 participants Est. completion 2016-07 1 site Stand-aloneOther conditions: Elderly, Delirium of Unknown (Axis III) Etiology, Intensive Care (ICU) MyopathyView official trial listing → -
Completed NCT NCT01658228
Combination Treatment Study for Memory Impairment and Depression
Not yet reported New York State Psychiatric Institute 86 participants Est. completion 2016-01 2 sitesOther conditions: Depression, Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT01677754
A Study of RO4602522 in Participants With Moderate Severity Alzheimer Disease on Background Alzheimer Disease Therapy
Not yet reported Hoffmann-La Roche 542 participants Est. completion 2015-06-12 142 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT01696591
The Long-Term Safety and Efficacy Follow-Up Study of Subjects Who Completed the Phase I Clinical Trial of Neurostem®-AD
Duk Lyul Na 14 participants Est. completion 2013-09 1 siteOther conditions: Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Delirium, Dementia, Amnestic, Cognitive Disorders, Mental DisordersView official trial listing → -
Terminated NCT NCT01712074
Study Evaluating TheSafety And Efficacy Of PF-05212377 Or Placebo In Subjects With Alzheimer's Disease With Existing Neuropsychiatric Symptoms On Donepezil
Not yet reported Pfizer 186 participants Est. completion 2015-09 60 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01738295
Donepezil Effect on Visual Attention and Training
Not yet reported Université de Montréal 20 participants Est. completion 2015-08 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT01743976
Donepezil Compared to Placebo in Patients With Chronic Neuropathic Pain
Not yet reported Wake Forest University 5 participants Est. completion 2013-10-23 2 sites Stand-aloneOther conditions: Neuropathic PainView official trial listing → -
Completed NCT NCT01772095
ADVANCE Study: Alzheimer Disease eVAluation iN Clinical PracticE
Elpen Pharmaceutical Co. Inc. 389 participants Est. completion 2013-11 1 siteOther conditions: Alzheimer Disease, Dementia, Cognitive DisordersView official trial listing → -
Withdrawn NCT NCT01822951
Cerebrolysin Compared to Donepezil in Patients With Mild to Moderate Dementia of Alzheimer's Type (DAT)
Not yet reported Ever Neuro Pharma GmbH Est. completion 2016-12 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT01843556
A Phase 1 Study of E2022 Tape Formulation for Different Application Sites and Intervals in Japanese Healthy Elderly Males
Not yet reported Eisai Co., Ltd. 48 participants Est. completion 2013-06 1 siteOther conditions: Healthy Elderly MaleView official trial listing → -
Completed NCT NCT01845636
Olfactory Deficits in MCI as Predictor of Improved Cognition on Donepezil
Not yet reported New York State Psychiatric Institute 41 participants Est. completion 2016-03 1 site Stand-aloneOther conditions: Mild Cognitive ImpairmentView official trial listing → -
Status unknown NCT NCT01849042
Effect of Memantine Oral Pump on Language in Patients With Probable Alzheimer's Disease
Not yet reported Konkuk University Medical Center 188 participants Est. completion 2015-08 1 siteOther conditions: Alzheimer's Disease, DementiaView official trial listing → -
Terminated NCT NCT01852110
Efficacy and Safety of MK-7622 as Adjunct Therapy in Participants With Alzheimer's Disease (MK-7622-012)
Not yet reported Merck Sharp & Dohme LLC 240 participants Est. completion 2016-04-11 Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01860625
A Phase I Clinical, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects
Not yet reported Icure Pharmaceutical Inc. 36 participants Est. completion 2014-02 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT01872598
Masitinib in Patients With Mild to Moderate Alzheimer's Disease
Not yet reported AB Science 721 participants Est. completion 2020-12 6 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT01877538
Study to Investigate the Ability of [11C]Donepezil PET to Image the Parasympathetic Nervous System
Per Borghammer 7 participants Est. completion 2013-07 1 siteOther conditions: Parkinson's DiseaseView official trial listing → -
Terminated NCT NCT01887132
A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism
Not yet reported National Institute of Mental Health (NIMH) 5 participants Est. completion 2015-12 1 site Stand-aloneOther conditions: Autism Spectrum DisordersView official trial listing → -
Completed NCT NCT01903824
Pharmacokinetics and Pharmacodynamics (PK/PD) of CEP-26401 in Healthy Subjects
Not yet reported Teva Branded Pharmaceutical Products R&D, Inc. 40 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Cognitive ImpairmentView official trial listing → -
Completed NCT NCT01923259
Bioavailability Study of Donepezil Hydrochloride Tablets 23 mg Under Fed Condition
Not yet reported Dr. Reddy's Laboratories Limited 94 participants Est. completion 2010-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01923558
Bioavailability Study of Donepezil Hydrochloride Tablets 23 mg Under Fasting Condition
Not yet reported Dr. Reddy's Laboratories Limited 76 participants Est. completion 2010-11 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT01940952
Zydena on Cognitive Function of Alzheimer's Disease Patients
Not yet reported Samsung Medical Center 210 participants 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01944436
A Genetic and Perfusion Study of Response to Cognitive Enhancers in Lewy Body Disease
Sunnybrook Health Sciences Centre 57 participants Est. completion 2016-01 1 siteOther conditions: Lewy Body DiseaseView official trial listing → -
Completed NCT NCT01951118
Olfactory Deficits and Donepezil Treatment in Cognitively Impaired Elderly
Not yet reported New York State Psychiatric Institute 121 participants Est. completion 2019-05 1 site Stand-aloneOther conditions: Alzheimer Disease, Mild Cognitive Impairment, Delirium, Dementia, Amnestic, Cognitive DisordersView official trial listing → -
Completed NCT NCT01955161
Study of Idalopirdine in Patients With Mild - Moderate Alzheimer's Disease Treated With Donepezil
Not yet reported H. Lundbeck A/S 933 participants Est. completion 2016-07 137 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT01972204
Intensive Instruction on the Use of Aricept
Not yet reported Mirai Iryo Research Center, Inc. 125 participants Est. completion 2017-08 1 siteOther conditions: Alzheimer's Type DementiaView official trial listing → -
Completed NCT NCT02006641
Idalopirdine in Patients With Mild-moderate Alzheimer's Disease Treated With Donepezil
Not yet reported H. Lundbeck A/S 858 participants Est. completion 2016-12 162 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02012595
[11C]Donepezil PET For Imaging The Autonomous Nervous System In Parkinsons Disease
Per Borghammer 24 participants Est. completion 2015-01 1 siteOther conditions: Parkinson's DiseaseView official trial listing → -
Completed NCT NCT02035982
Discontinuation of Cholinesterase Inhibitors for the Treatment of Severe Alzheimer's Disease
Not yet reported Sunnybrook Health Sciences Centre 40 participants Est. completion 2015-09 2 sitesOther conditions: Alzheimer's Disease, DementiaView official trial listing → -
Completed NCT NCT02051335
Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy Adults
Not yet reported AstraZeneca 27 participants Est. completion 2014-05 1 site Stand-aloneOther conditions: Memory Impairment, Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02055703
A 3-Part, Open-Label, Drug-Drug Interaction Study of Concomitant Administration of E2609 With Itraconazole, Rifampin, Digoxin, or Donepezil
Not yet reported Eisai Inc. 195 participants Est. completion 2014-05 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT02064920
Computerized Cognition Testing in Participants With Mild Alzheimer's Disease (AD) Treated With Donepezil (MK-0000-318)
Not yet reported Merck Sharp & Dohme LLC 36 participants Est. completion 2016-07-13 Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02079246
Long-term Safety and Tolerability of Idalopirdine (Lu AE58054) as Adjunctive Treatment to Donepezil in Patients With Mild-moderate Alzheimer's Disease
Not yet reported H. Lundbeck A/S 1463 participants Est. completion 2017-07-06 258 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02087865
Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's Disease
Not yet reported The Cleveland Clinic 89 participants Est. completion 2021-12-20 1 siteOther conditions: Genetic Risk for Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02094053
A Double-blind, Placebo-controlled Comparative Study and Open-label Extension Study to Confirm the Efficacy and Safety of E2020 in Subjects With Down Syndrome Having Regression Symptoms and Disabled Activities of Daily Living.
Not yet reported Eisai Co., Ltd. 36 participants Est. completion 2017-04-21 10 sites Stand-aloneOther conditions: Down SyndromeView official trial listing → -
Completed NCT NCT02097056
Safety and Efficacy of Donepezil HCl 23 mg in Patients With Moderate to Severe Alzheimer's Disease
Not yet reported Eisai Korea Inc. 171 participants Est. completion 2015-05 13 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02158910
A Plan on Investigation and Collection of Aricept Safety Information With a Dose Increase on Alzheimer's Disease Patients
Eisai Korea Inc. 2231 participants Est. completion 2016-06 13 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02162251
Post-marketing Surveillance of Donepezil Hydrochloride Investigation of the Safety and Effectiveness of Combination Therapy of Donepezil Hydrochloride and Memantine Hydrochloride in Patients With Alzheimer's Disease
Eisai Co., Ltd. 3482 participants Est. completion 2016-04-15 1 siteOther conditions: Alzheimer's DeseaseView official trial listing → -
Completed NCT NCT02162264
Post-marketing Surveillance of Donepezil Hydrochloride -Investigation of the Factors That Affect Aricept Medication Persistence Rate and the Safety and Efficacy in Patients With Alzheimer's Disease in Clinical Practice
Eisai Co., Ltd. 8662 participants Est. completion 2016-07-22 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02178124
A Phase I Clinical Study, Randomized, Single-blind, Placebo-controlled, Multiple Doses, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Donepezil Patch in Healthy Male Subjects.
Not yet reported Icure Pharmaceutical Inc. 24 participants Est. completion 2014-12 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT02187276
The Predictive Factors of Good Clinical Response to Cholinesterase Inhibitors in Alzheimer Disease and Mixed Dementia
Federal University of Minas Gerais 129 participants Est. completion 2013-03Other conditions: Alzheimer Disease, Late OnsetView official trial listing → -
Completed NCT NCT02206620
Effects of Cholinergic Augmentation on Measures of Balance and Gait
Not yet reported Oregon Health and Science University 49 participants Est. completion 2017-07 1 site Stand-aloneOther conditions: Parkinson's DiseaseView official trial listing → -
Terminated NCT NCT02222727
Effects of Donepezil on Regional Cerebral Blood Flow Following Aneurysmal Subarachnoid Haemorrhage
Not yet reported St George's, University of London 19 participants Est. completion 2016-11 1 siteOther conditions: Aneurysmal Subarachnoid Hemorrhage, Delayed Neurological Deficit, Delayed Cerebral Ischemia, VasospasmView official trial listing → -
Completed NCT NCT02255799
Multicenter Evaluation of Memory Remediation After TBI With Donepezil
Not yet reported Baylor College of Medicine 75 participants Est. completion 2024-12-04 4 sitesOther conditions: Traumatic Brain Injury, Memory DeficitsView official trial listing → -
Completed NCT NCT02262975
A Multi-national Study to Identify Treatment Discontinuation Rate in de Novo Alzheimer's Disease Patients Who Have Been Newly Prescribed With Donepezil (Aricept) in Asia (ADOS)
Eisai Korea Inc. 532 participants Est. completion 2016-08 26 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02264353
The Impact of Arousal Threshold in Obstructive Sleep Apnea
Not yet reported University of California, San Diego 44 participants Est. completion 2015-05 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Status unknown NCT NCT02305836
Effect of Electroacupuncture Combined With Donepezil for Treating Alzheimer's Disease
Not yet reported Guang'anmen Hospital of China Academy of Chinese Medical Sciences 334 participants Est. completion 2019-12 1 site Stand-aloneOther conditions: Cognitive ImpairmentView official trial listing → -
Terminated NCT NCT02331771
Donepezil Memory Preservation Post ECT
Not yet reported Porter Adventist Hospital 12 participants Est. completion 2017-03-24 1 siteOther conditions: Memory ImpairmentView official trial listing → -
Completed NCT NCT02337907
BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease.
Not yet reported Boehringer Ingelheim 329 participants Est. completion 2017-10-10 60 sitesOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT02345213
A Post-Marketing Clinical Study of Aricept in Patients With Dementia With Lewy Bodies (DLB)
Not yet reported Eisai Co., Ltd. 160 participants Est. completion 2018-03-26 1 siteOther conditions: Dementia, Lewy Body, Lewy Body DiseaseView official trial listing → -
Terminated NCT NCT02374567
Pharmacovigilance in Gerontopsychiatric Patients
Not yet reported Hannover Medical School 407 participants Est. completion 2017-06-28 5 sites Stand-aloneOther conditions: Dementia, Depression, Schizophrenia, Psychosomatic Disorders, Anxiety DisordersView official trial listing → -
Completed NCT NCT02406261
A Drug-Drug Interaction Study of Lanabecestat (LY3314814) in Healthy Participants
Not yet reported AstraZeneca 82 participants Est. completion 2015-08-31 2 sites Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02415062
The Efficacy and Safety Study of High Dose Donepezil in Parkinson's Disease With Dementia
Not yet reported Inje University 150 participants Est. completion 2017-12 1 site Stand-aloneOther conditions: Parkinson's DiseaseView official trial listing → -
Completed NCT NCT02448784
Post-marketing Surveillance of Donepezil Hydrochloride - Investigation of Long Term Safety and Efficacy of Aricept as Well as Its Proper Use Information in Patients With Dementia With Lewy Bodies (DLB).
Eisai Co., Ltd. 591 participants Est. completion 2017-03-30 1 siteOther conditions: Dementia With Lewy Body DiseaseView official trial listing → -
Status unknown NCT NCT02450786
Effect of Donepezil on Cognition in Parkinson's Disease With Mild Cognitive Impairment (PD-MCI)
Not yet reported Yonsei University 80 participants Est. completion 2019-08 1 site Stand-aloneOther conditions: Parkinson's DiseaseView official trial listing → -
Completed NCT NCT02453932
Efficacy and Safety of Tianzhi Granule in Mild to Moderate Vascular Dementia
Not yet reported Dongzhimen Hospital, Beijing 543 participants Est. completion 2017-05 1 site Stand-aloneOther conditions: Vascular DementiaView official trial listing → -
Terminated NCT NCT02487082
Pilot Study of Sleep Therapy and Biomarkers in Children With Autism Spectrum Disorders
Not yet reported Stony Brook University 12 participants Est. completion 2021-01-29 1 siteOther conditions: Autism Spectrum DisorderView official trial listing → -
Completed NCT NCT02549196
A Dose Titration Study of CPC-201 in Patients With Dementia of Alzheimer's Type
Not yet reported Chase Pharmaceuticals Corporation, an affiliate of Allergan plc 28 participants Est. completion 2017-09-28 4 sites Stand-aloneOther conditions: Dementia of Alzheimer's TypeView official trial listing → -
Completed NCT NCT02550665
Optimal Dose Escalation Strategy to Successful Achievement of High Dose Donepezil 23mg
Not yet reported Asan Medical Center 176 participants Est. completion 2016-10 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02570581
MELA Study - Hedonic Study on the Taste of Drugs Crushed in Food: Observational Study Involving 16 Healthy Volunteers
Not yet reported Centre Hospitalier Universitaire de Nice 16 participants Est. completion 2014-07 1 siteOther conditions: HealthyView official trial listing → -
Terminated NCT NCT02573519
Gastrointestinal Motility Among Diabetes Patients
Not yet reported University of Aarhus 40 participants Est. completion 2019-02-11 1 siteOther conditions: Diabetic Autonomic Neuropathy, Gastrointestinal Motility Disorder, Diabetes Mellitus, Change of Transit or CirculationView official trial listing → -
Completed NCT NCT02580305
SUVN-502 With Donepezil and Memantine for the Treatment of Moderate Alzheimer's Disease- Phase 2a Study
Not yet reported Suven Life Sciences Limited 564 participants Est. completion 2019-11-07 71 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02585934
Study Evaluating Intepirdine (RVT-101) in Subjects With Mild to Moderate Alzheimer's Disease on Donepezil: MINDSET Study
Not yet reported Axovant Sciences Ltd. 1315 participants Est. completion 2017-09 197 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT02586909
12-Month Open-Label Extension Study of Intepirdine (RVT-101) in Subjects With Alzheimer's Disease: MINDSET Extension
Not yet reported Axovant Sciences Ltd. 1099 participants Est. completion 2018-03-12 169 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT02623764
EEG-cholinergic Index and Clinical Response to Treatment With Cholinesterase Inhibitors
Landspitali University Hospital 218 participants Est. completion 2019-11Other conditions: Alzheimer´s DiseaseView official trial listing → -
Completed NCT NCT02626572
Efficacy and Safety of 3 Doses of S47445 Versus Placebo in Patients With Alzheimer's Disease at Mild to Moderate Stages With Depressive Symptoms
Not yet reported Institut de Recherches Internationales Servier 500 participants Est. completion 2017-09 78 sitesOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02635750
Investigation of Pharmacokinetic Drug-drug Interaction of BI 409306 and Donepezil in Healthy Male and Female Subjects
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2016-04-04 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT02648906
A Clinical Trial for an Evaluation of Choline Alfoscerate and Donepezil for Cognitive Improvements of Patients With Cerebrovascular Injury in Alzheimer Patients
Not yet reported Daewoong Pharmaceutical Co. LTD. 128 participants 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT02660983
A Study of Donepezil Hydrochloride in Patients With Dementia Associated With Cerebrovascular Disease
Not yet reported Eisai Co., Ltd. 302 participants Est. completion 2018-12-21 31 sites Stand-aloneOther conditions: Dementia Associated With Cerebrovascular DiseaseView official trial listing → -
Enrolling by invitation NCT NCT02670161
Quality Improvement and Practice Based Research in Neurology Using the EMR
Not yet reported Endeavor Health 3300 participants Est. completion 2027-12 1 siteCardiovascular disease Other conditions: Brain Tumors, Epilepsy, Migraine, Mild Cognitive Impairment, Concussion, Multiple Sclerosis, Neuropathy, Parkinson's, Restless Legs SyndromeView official trial listing → -
Completed NCT NCT02695004
Safety, Tolerability and Pharmacokinetics of DKF-310 ( (Donepezil).
Not yet reported Dongkook Pharmaceutical Co., Ltd. 44 participants Est. completion 2017-03 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT02696512
A Study of IBRF Disorders of Consciousness Advanced Care/MultiModal Care Protocol in Severe Disorders of Consciousness
Not yet reported, Not yet reported International Brain Research Foundation 30 participants Est. completion 2017-04 1 site Stand-aloneOther conditions: Brain InjuryView official trial listing → -
Completed NCT NCT02703636
NextStep:Study to Evaluate Safety,Efficacy & Tolerability of Rivastigmine Patch in Mild to Moderate Alzheimer's Patients.
Not yet reported Novartis Pharmaceuticals 118 participants Est. completion 2018-05-07 19 sitesOther conditions: Mild to Moderate Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02711683
DL-3-n-butylphthalide Treatment in Patients With Mild to Moderate Alzheimer's Disease Already Receiving Donepezil
First Affiliated Hospital Xi'an Jiaotong University 92 participants Est. completion 2019-12 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT02769065
Study of TAK-071 in Healthy Participants and Participants With Mild Cognitive Impairment/Mild Alzheimer Disease and Relative Bioavailability (BA) and Food Effect of TAK-071 in Healthy Participants
Not yet reported Takeda 179 participants Est. completion 2017-06-08 1 site Stand-aloneOther conditions: Alzheimer Disease, Healthy VolunteersView official trial listing → -
Completed NCT NCT02787746
Safety and Efficacy of Donepezil in Mild to Moderate Alzheimer's Disease
Not yet reported Beijing Friendship Hospital 241 participants Est. completion 2019-03 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT02822573
Phase 3 Randomized Placebo Controlled Clinical Trial of Donepezil
Not yet reported Wake Forest University Health Sciences 276 participants Est. completion 2022-07-29 278 sitesOther conditions: Cognitive Dysfunction, Memory ImpairmentView official trial listing → -
Withdrawn NCT NCT02857244
A Multidisciplinary Approach to Manage Gait Difficulty in Parkinson Patients
Not yet reported University of Chicago Est. completion 2017-11 1 siteOther conditions: Parkinson's DiseaseView official trial listing → -
Withdrawn NCT NCT02860065
CPC-201 Alzheimer's Disease Type Dementia: PET Study
Not yet reported Chase Pharmaceuticals Corporation, an affiliate of Allergan plc Est. completion 2017-06-30 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Terminated NCT NCT02918266
TAK-071 Scopolamine-Induced Cognitive Impairment Study
Not yet reported Takeda 18 participants Est. completion 2017-08-08 1 site Stand-aloneOther conditions: Healthy VolunteersView official trial listing → -
Status unknown NCT NCT02927522
Donepezil Attenuate Postoperative Cognitive Dysfunction
Not yet reported RenJi Hospital 550 participants Est. completion 2021-12 1 site Stand-aloneOsteoarthritis Other conditions: Femoral Head Necrosis, Rheumatoid ArthritisView official trial listing → -
Completed NCT NCT02968719
A Phase 1, Corplex™ Donepezil Transdermal System Compared to Oral Aricept®
Not yet reported Corium, Inc. 107 participants Est. completion 2017-07-11 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT02988908
Memory and Mental Health in Aging
Not yet reported Stanford University 198 participants Est. completion 2007-09 1 site Stand-aloneOther conditions: MemoryView official trial listing → -
Status unknown NCT NCT03011476
Effect of Acetylcholinesterase Inhibitors on the Gait of the Patients With Parkinson Disease
Not yet reported Kyung Hee University Hospital 20 participants Est. completion 2018-12-30 1 siteOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT03030105
Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy Volunteers
Not yet reported Tetra Discovery Partners 38 participants Est. completion 2017-06 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03055741
Study of DHP1401 in Patients With Mild-moderate Alzheimer's Disease Treated With Donepezil(DRAMA)
Not yet reported Daehwa Pharmaceutical Co., Ltd. 180 participants Est. completion 2019-08 16 sites Stand-aloneOther conditions: Mild-moderate Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT03073876
Detecting an Early Response to Donepezil With Measures of Visual Attention
Not yet reported NYU Langone Health 25 participants Est. completion 2021-01-13 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT03090516
Clinical Efficacy of Ginkgo Biloba Extract in the Treatment of Alzheimer's Disease
Not yet reported, Not yet reported The First Affiliated Hospital with Nanjing Medical University 240 participants Est. completion 2020-03-10 1 site Stand-aloneOther conditions: Alzheimer'sView official trial listing → -
Completed NCT NCT03109314
Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia
Not yet reported Dennis Levi 20 participants Est. completion 2018-12-01 1 siteOther conditions: AmblyopiaView official trial listing → -
Status unknown NCT NCT03151382
A Based on PEEG and PET Study of Anxiolytic Treatment to Improve Cognitive Function in Patients With Alzheimer Disease
Not yet reported Zhejiang Provincial People's Hospital 30 participants Est. completion 2018-06-30 Stand-aloneOther conditions: Alzheimer Disease, Cognitive FunctionView official trial listing → -
Completed NCT NCT03184467
Clinical Trial to Evaluate the Efficacy and Safety of GV1001 in Alzheimer Patients
Not yet reported GemVax & Kael 96 participants Est. completion 2019-09-19 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03197740
A Multinational, Multi-center, Randomized, Double-blind, Active Comparator, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Donepezil Transdermal Patch in Patients With Alzheimer's Disease
Not yet reported Icure Pharmaceutical Inc. 399 participants Est. completion 2020-07-20 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03221894
A Retrospective Study to Investigate the Additive Effectiveness of Chinese Herbal Medicine in Alzheimer's Disease
Dongzhimen Hospital, Beijing 120 participants Est. completion 2021-07-31 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03259958
A Bioequivalence Study of Corplex™ Donepezil Transdermal Delivery System Compared to Aricept®
Not yet reported Corium, Inc. 86 participants Est. completion 2018-03-14 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT03283059
Octohydroaminoacridine Succinate Tablet for Mild-to-Moderate Alzheimer's Disease
Not yet reported Shanghai Mental Health Center 600 participants Est. completion 2021-02-16 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT03299257
Donepezil, Residual Excessive Daytime Sleepiness, Obstructive Sleep Apnea
Not yet reported Associação Fundo de Incentivo à Pesquisa 36 participants Est. completion 2019-03-02 1 siteObstructive sleep apnea Other conditions: SleepinessView official trial listing → -
Withdrawn NCT NCT03316898
A FDG-PET Study of AGN-242071 Added to Standard-of-Care (Donepezil ± Memantine) for the Treatment of Participants With Mild to Moderate Alzheimer's Disease
Not yet reported Allergan Est. completion 2018-11-04 6 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT03349320
Response to Donepezil, Drug Plasma Concentration and the CYP2D6 and APOE Genetic Polymorphisms
Federal University of Minas Gerais 37 participants Est. completion 2013-03Other conditions: Late Onset Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT03352739
Fornix and NbM as Targets of Stimulation In Alzheimer's Disease
Not yet reported Xuanwu Hospital, Beijing 30 participants Est. completion 2020-12-01 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03397862
A Skin Irritation Assessment of Once-Weekly Corplex™ Donepezil Transdermal Delivery System
Not yet reported Corium, Inc. 256 participants Est. completion 2018-04-02 2 sites Stand-aloneOther conditions: Skin Irritation, SensitizationView official trial listing → -
Completed NCT NCT03432195
A Clinical Study to Evaluate the Pharmacokinetics (PK) of Corplex™ Donepezil Transdermal Delivery System (TDS) Applied to Different Body Locations
Not yet reported Corium, Inc. 66 participants Est. completion 2018-06-28 1 site Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT03438604
A Study to Evaluate the Effect of Heat Application on the Delivery Profile of Corplex™ Donepezil Transdermal Delivery System (TDS)
Not yet reported Corium, Inc. 24 participants Est. completion 2018-06-30 1 siteOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT03441516
Effect of Choline Alphoscerate on Cognitive Function in Alzheimer's Dementia
Not yet reported Yuhan Corporation 79 participants Est. completion 2021-12-31 6 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Not yet recruiting NCT NCT03454646
Comparison of Therapeutic Strategies With Cholinesterase Inhibitors (SOS TRIAL)
Not yet reported University Hospital, Bordeaux 1205 participants Est. completion 2027-09-15 31 sites Stand-aloneOther conditions: Alzheimer Disease, Cholinesterase InhibitorsView official trial listing → -
Completed NCT NCT03565809
Quality of the Management of Diabetes in Elderly People With Dementia in France
University Hospital, Toulouse 87816 participants Est. completion 2018-12-31 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03569579
CKD-355 Drug-drug Interaction Study (CKD-355 DDI P1)
Not yet reported Chong Kun Dang Pharmaceutical 20 participants Est. completion 2018-06-04 1 site Stand-aloneOther conditions: Central Nervous System DiseasesView official trial listing → -
Completed NCT NCT03599726
Improving Walking Automaticity in Parkinson's Disease: Levodopa or Donepezil
Not yet reported Oregon Health and Science University 20 participants Est. completion 2019-07-30 1 site Stand-aloneOther conditions: Parkinson DiseaseView official trial listing → -
Completed NCT NCT03698695
A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers
Not yet reported Theranexus 152 participants Est. completion 2019-12-20 7 sites Stand-aloneOther conditions: Cognitive Impairment, Alzheimer DiseaseView official trial listing → -
Withdrawn NCT NCT03740178
Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005)
Not yet reported Merck Sharp & Dohme LLC Est. completion 2020-02-28 Stand-aloneOther conditions: Alzheimer's Disease, Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT03905096
A Study in Healthy Men and Women to Test Which Effects Donepezil and BI 425809 Have on Each Other
Not yet reported Boehringer Ingelheim 32 participants Est. completion 2019-08-30 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT03907371
The Effect of Donepezil in Radiotherapy-related Cognitive Impairment.
Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 238 participants Est. completion 2022-12-31 1 site Stand-aloneOther conditions: Radiation Injuries, Cognitive ImpairmentView official trial listing → -
Completed NCT NCT03932916
Safety and Pharmacokinetic of Donepezil Pamoate in Healthy Subjects
Not yet reported Shanghai Synergy Pharmaceutical Sciences Co., Ltd. 38 participants Est. completion 2020-09-11 1 site Stand-aloneOther conditions: ADView official trial listing → -
Status unknown NCT NCT03943420
One Research on Improving Cognitive Impairment Caused by Hypertension
Jiangsu Famous Medical Technology Co., Ltd. 144 participants Est. completion 2020-12 1 siteOther conditions: HypertensionView official trial listing → -
Status unknown NCT NCT03954613
Evaluation of the Contribution of Regular Cognitive Exercises to Treatment in Patients With Alzheimer's Disease
Not yet reported Neutec Ar-Ge San ve Tic A.Ş 198 participants Est. completion 2024-03-01 1 site Stand-aloneOther conditions: Alzheimer Disease, Cognitive ChangeView official trial listing → -
Completed NCT NCT04013477
Single-ascending Dose Phase 1 Clinical Trial to Evaluate the Safety and PK of DA-5207 TDS in Healthy Adults
Not yet reported Dong-A ST Co., Ltd. 40 participants Est. completion 2020-04-06 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT04117178
Monitoring Anti-Dementia Drugs by Serum Levels
Not yet reported Zealand University Hospital 132 participants Est. completion 2023-02-16 1 site Stand-aloneOther conditions: Dementia, Dementia With Lewy Bodies, Dementia in Parkinsons Disease, Dementia Alzheimers, Alzheimer DiseaseView official trial listing → -
Completed NCT NCT04134416
Brain Correlates of Multimodal Rehabilitation in Chronic Post-stroke Aphasia
Not yet reported University of Malaga 20 participants Est. completion 2020-10-20 1 site Stand-aloneCardiovascular disease Other conditions: AphasiaView official trial listing → -
Completed NCT NCT04308304
MK-1942/Donepezil Interactions in Participants With Alzheimer's Disease (MK-1942-005)
Not yet reported Merck Sharp & Dohme LLC 27 participants Est. completion 2022-05-18 4 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Completed NCT NCT04318639
The Combination of Donepezil and Cognitive Training for Treating Alcohol Use Disorder
Not yet reported, Not yet reported VA Connecticut Healthcare System 15 participants Est. completion 2019-12-31 1 site Stand-aloneAlcohol use disorder Other conditions: Mild Cognitive ImpairmentView official trial listing → -
Status unknown NCT NCT04423276
Efficiency of Donepezil in Elderly Patients for Prevention of POCD Dysfunction
Not yet reported RenJi Hospital 360 participants Est. completion 2022-12-01 1 site Stand-aloneOther conditions: Total Knee Arthroplasty, Fracture of Head of Femur Articular Displaced, Protrusion of Intervertebral DiscView official trial listing → -
Status unknown NCT NCT04479865
Phase 1 Clinical Trial to Evaluate the Safety, PK and PD of DA-5207 TDS in Healthy Adults
Not yet reported Dong-A ST Co., Ltd. 49 participants Est. completion 2021-04-30 1 siteOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT04505670
The Effect of Donepezil on Wound Healing
Not yet reported University of Maryland, Baltimore 20 participants Est. completion 2023-07-30 1 site Stand-aloneOther conditions: Wound HealView official trial listing → -
Terminated NCT NCT04507438
The Effect of Donepezil on Glycemic Control in Type II Diabetics
Not yet reported University of Maryland, Baltimore 7 participants Est. completion 2023-09-12 1 site Stand-aloneType 2 diabetesView official trial listing → -
Completed NCT NCT04617782
Pharmacokinetic Study of 5 and 10 mg Corplex™ Donepezil TDS Compared to 10 mg Aricept® in Healthy Volunteers
Not yet reported Corium, Inc. 60 participants Est. completion 2021-04-05 1 site Stand-aloneOther conditions: Healthy SubjectsView official trial listing → -
Completed NCT NCT04730635
Cognition Platform Study in Participants at Risk for Alzheimer's Disease (AD) (MK-0000-413)
Not yet reported Merck Sharp & Dohme LLC 44 participants Est. completion 2023-02-06 10 sites Stand-aloneOther conditions: Alzheimer's Disease, Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT04731311
Telerehabilitation Alzheimer's Disease Usability (TADU)
Not yet reported Bright Cloud International Corp 4 participants Est. completion 2021-09-07 1 siteOther conditions: Alzheimer Disease, Healthy AgingView official trial listing → -
Status unknown NCT NCT04732182
Telerehabilitation Alzheimer's Disease Feasibility (TADF)
Not yet reported Bright Cloud International Corp 14 participants Est. completion 2023-02-28 2 sitesOther conditions: Alzheimer Disease, Healthy AgingView official trial listing → -
Completed NCT NCT05003063
Effects of Acetylcholine and Attention on Visual Spatial Representations in the Brain
Not yet reported University of California, Berkeley 12 participants Est. completion 2021-08-02 1 siteOther conditions: Visual Perception, Attention, Information Processing, Cholinergic SystemView official trial listing → -
Completed NCT NCT05078944
Progress of Mild Alzheimer's Disease in Participants on Acupuncture Versus Sham Acupuncture
Not yet reported Shanghai Institute of Acupuncture, Moxibustion and Meridian 160 participants Est. completion 2025-09-10 1 site Stand-aloneOther conditions: Alzheimer Disease 1View official trial listing → -
Completed NCT NCT05102045
The Effects of Repetitive Transcranial Magnetic Stimulation in Patients With Alzheimer's Disease
Not yet reported Istanbul Medipol University Hospital 27 participants Est. completion 2017-06-01 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT05114499
Efficacy and Safety of Donepezil and Sodium Oligomannate in Patients With Mild to Moderate Alzheimer's Disease
First Affiliated Hospital Xi'an Jiaotong University 150 participants Est. completion 2024-12Other conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT05127746
Phase 1 Clinical Trial of DA-5207 in Healthy Adults
Not yet reported Dong-A ST Co., Ltd. 51 participants Est. completion 2022-12-13 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT05254639
Donepezil for Oxaliplatin-induced Neuropathy Peripheral Neuropathy: Proof of Concept Study
Not yet reported University Hospital, Clermont-Ferrand 77 participants Est. completion 2024-01-24 34 sites Stand-aloneOther conditions: Digestive Oncology, Supportive CareView official trial listing → -
Completed NCT NCT05321680
Withdrawal of Antidementia Drugs in Advanced Dementia (WADAD)
Not yet reported Centro Hospitalar De São João, E.P.E. 16 participants Est. completion 2022-03-20 1 site Stand-aloneOther conditions: DementiaView official trial listing → -
Active, not recruiting NCT NCT05345509
A Clinical Trial to Access Pharmacokinetic Profiles and Safety of IVL3003.
Not yet reported, Not yet reported Inventage Lab., Inc. 62 participants Est. completion 2025-11-13 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT05383183
Efficacy and Safety of ChOline ALfoscerate in Patient With Mild to Moderate Alzheimer's Disease
Not yet reported Daewoong Bio Inc. 630 participants Est. completion 2025-12-09 4 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Active, not recruiting NCT NCT05438264
Effect of Donepezil on Speech Recognition in Cochlear Implant Users
Not yet reported Vanderbilt University Medical Center 50 participants Est. completion 2026-09-01 1 site Stand-aloneOther conditions: Bilateral Sensorineural Hearing LossView official trial listing → -
Status unknown NCT NCT05488041
Anal Manometry Examination in Patients With Ulcerative Colitis
Not yet reported Assaf-Harofeh Medical Center 150 participants Est. completion 2023-12 1 siteOther conditions: Ulcerative ColitisView official trial listing → -
Status unknown NCT NCT05518409
Immunohistochemical Study of Neurodegenerative Diseases
Not yet reported First Affiliated Hospital of Zhejiang University 100 participants Est. completion 2023-12-30 1 site Stand-aloneOther conditions: Alzheimer Disease, Lewy Body Disease, Neurodegenerative DiseasesView official trial listing → -
Completed NCT NCT05525780
Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics of Donepezil From Single Dose of GB-5001 IM Depot and Aricept® Oral Tablets in Healthy Male Volunteers
Not yet reported G2GBio, Inc. 48 participants Est. completion 2023-06-02 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT05538507
Efficacy of Chinese Traditional Medicine "Smart Soup" in Cognition and Behavior Regulation in Alzheimer's Disease
Not yet reported Peking Union Medical College Hospital 180 participants Est. completion 2024-06 1 siteOther conditions: Alzheimer Disease, Mild Cognitive ImpairmentView official trial listing → -
Status unknown NCT NCT05540977
Donepezil Prevents Urinary Retention After Extensive Total Hysterectomy
Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 108 participants Est. completion 2023-07-15 1 site Stand-aloneOther conditions: Urinary Retention After ProcedureView official trial listing → -
Not yet recruiting NCT NCT05564169
Masitinib in Patients With Mild Alzheimer's Disease
Not yet reported AB Science 600 participants Est. completion 2029-12 9 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT05641480
Technical R&D and Demonstration of Intelligent Medical Care in Alzheimer's Disease's Management
Not yet reported Shaanxi Hospital of Traditional Chinese Medicine 150 participants Est. completion 2025-12-09 2 sites Stand-aloneOther conditions: Alzheimer Disease, Subjective Cognitive Decline, Mild Cognitive Impairment, Mild DementiaView official trial listing → -
Status unknown NCT NCT05709301
Randomized Clinical Trial of Donepezil for the Treatment of Mild Cognitive Impairment in Parkinson's Disease
Not yet reported Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 120 participants Est. completion 2025-11-01 Stand-aloneOther conditions: Parkinson Disease, Mild Cognitive ImpairmentView official trial listing → -
Completed NCT NCT05804279
Pharmacokinetics of BPDO-1603 or BPDO-16031 and BPDO-16033 Administration in Healthy Adults
Not yet reported Hyundai Pharm 24 participants Est. completion 2023-03-14 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Status unknown NCT NCT05811000
A Phase 2 Clinical Study to Explore the Optimal Dosage/Administration of PM012 Tablet in Alzheimer's Disease
Not yet reported, Not yet reported Mediforum Ltd., Co. 312 participants Est. completion 2024-08-13 1 site Stand-aloneOther conditions: Mild Alzheimer DiseaseView official trial listing → -
Status unknown NCT NCT06127368
Dose-Escalation Study to Assess the Safety, Tolerability, and Pharmacokinetics From Single Dose of Intramuscular (IM) and Subcutaneous (SC) Donepezil (GB-5001) Injections Versus Donepezil Oral Tablet (Aricept®) in Healthy Male Volunteers
Not yet reported G2GBio, Inc. 56 participants Est. completion 2025-01-14 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT06285240
Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia Taking Stable Donepezil Treatment (MK-1167-007)
Not yet reported Merck Sharp & Dohme LLC 28 participants Est. completion 2024-09-23 3 sites Stand-aloneOther conditions: Alzheimer's DiseaseView official trial listing → -
Status unknown NCT NCT06373094
A Single Dose Escalation Study of HHT201 in Healthy Subjects
Not yet reported Shanghai Synergy Pharmaceutical Sciences Co., Ltd. 64 participants Est. completion 2025-03-31 1 site Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT06393413
To Explore the Therapeutic Potential of Jiedu Yizhi Formula for Alzheimer 's Disease
Not yet reported Changchun University of Chinese Medicine 62 participants Est. completion 2024-04-01 1 siteOther conditions: Ensure the Legality and Compliance of the Testing ProcessView official trial listing → -
Not yet recruiting NCT NCT06518941
An Open Trial of a Novel Pharmacotherapy for Habit Modification in Anorexia Nervosa
Not yet reported New York State Psychiatric Institute 10 participants Est. completion 2028-12 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Not yet recruiting NCT NCT06687993
Acetylcholinesterase Inhibitor in Anorexia Nervosa: Multicenter, Double-Blind, Placebo-Controlled Trial
Not yet reported Centre Hospitalier St Anne 147 participants Est. completion 2030-05 Stand-aloneObstructive sleep apneaView official trial listing → -
Completed NCT NCT06774261
Phenserine on the Alzheimer's Treatment Horizon, Study 1
Not yet reported Helse Stavanger HF 16 participants Est. completion 2025-12-08 1 siteOther conditions: Alzheimer Disease, Mild Cognitive ImpairmentView official trial listing → -
Not yet recruiting NCT NCT06828289
Rivastigmine Mini-Tablet for Alzheimer's Disease
Peking University First Hospital 1000 participants Est. completion 2026-12-31Other conditions: Alzheimer's DiseaseView official trial listing → -
Not yet recruiting NCT NCT06840054
The Safety and Efficacy of Sodium Pentaborate Pentahydrate in Patients With Mild to Moderate Alzheimer's Disease
Not yet reported Tabriz University of Medical Sciences 30 participants Est. completion 2026-01-30 Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT06903910
Investigating the Cholinergic Contribution to Gait Dysfunction in Parkinson's Disease
Not yet reported University of Virginia 6 participants Est. completion 2026-01-31 1 site Stand-aloneOther conditions: Parkinson DiseaseView official trial listing → -
Not yet recruiting NCT NCT07060391
A Prospective Multicenter RCT Study of Deep Jugular Lymphovenous Anastomosis in the Treatment of Alzheimer's Disease
Not yet reported Shanghai Jiao Tong University School of Medicine 186 participants Est. completion 2027-01-31Other conditions: Alzheimer's DiseaseView official trial listing → -
Not yet recruiting NCT NCT07152418
Therapeutic Efficacy of Monoclonal Antibody Drugs for Alzheimer's Disease Based on PET Research
Second Affiliated Hospital, Zhejiang University, School of Medicine 120 participants Est. completion 2028-09-01Other conditions: Alzheimer Disease (AD), Alzheimer Dementia, Mild Cognitive Impairment (MCI)View official trial listing → -
Active, not recruiting NCT NCT07153991
Efficacy of Donepezil in Patients With Chronic Tinnitus
Not yet reported University of Sao Paulo 70 participants Est. completion 2025-12-09 1 site Stand-aloneOther conditions: TinnitusView official trial listing → -
Completed NCT NCT07351773
Ultrasound-Guided Stellate Ganglion Block for Alzheimer's Disease
Not yet reported Taizhou Second People's Hospital 40 participants Est. completion 2025-11-29 1 site Stand-aloneOther conditions: Alzheimer's Disease(AD), Cognitive DysfunctionView official trial listing → -
Not yet recruiting NCT NCT07680660
Efficacy of Lymphatic-Venous Anastomosis Plus Donepezil Versus Donepezil Alone for Alzheimer's Disease
Not yet reported Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 216 participants Est. completion 2029-03-31 1 site Stand-aloneOther conditions: Alzheimer s DiseaseView official trial listing → -
Not yet recruiting NCT NCT07768592
A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2511 in Participants With Early Alzheimer's Disease (AD)
Not yet reported Eisai Inc. 32 participants Est. completion 2030-05-06 Stand-aloneOther conditions: Alzheimers DiseaseView official trial listing → -
Completed NCT NCT07799090
Pharmacokinetic Study of GB-5001A 280 mg Long Acting Injection, in Comparison With the Comparator Drug Aricept® 5 mg and Aricept® 10 mg Film-coated Tablet in Healthy Subjects
Not yet reported G2GBio, Inc. 28 participants Est. completion 2026-04-15 1 site Stand-aloneOther conditions: Bioavailability Study on Healthy VolunteersView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Donepezil Hydrochloride, Donepezil
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