About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Donanemab
- Company
- Eli Lilly and Company
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 6 recruiting
Efficacy results: Not yet reported
6 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 23, 2026
Find a Clinical Trial Near Me
See recruiting studies for Donanemab and check eligibility with the study team.
Trial details
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Recruiting NCT NCT06566170
A Real-World Comparative Study of Donanemab (LY3002813) Plus Usual Care Versus Usual Care Alone in US Participants With Early Symptomatic Alzheimer's Disease
Eli Lilly and Company 6250 participants Est. completion 2033-02 1 siteOther conditions: Alzheimer DiseaseView official trial listing → -
Recruiting NCT NCT06957418
Alzheimer's Tau Platform: Master Protocol
Not yet reported Paul S. Aisen 900 participants Est. completion 2028-08-31 3 sites Stand-aloneOther conditions: Preclinical Alzheimer's Disease, Alzheimer Disease, Prodromal Alzheimer's DiseaseView official trial listing → -
Recruiting NCT NCT06996730
A Study of Donanemab, RG6289, or the Combination of Donanemab and RG6289 in Presenilin 1 (PSEN1) E280A Mutation Carriers for the Treatment of Autosomal-Dominant Alzheimer's Disease
Not yet reported, Not yet reported Banner Health 240 participants Est. completion 2030-06-01 1 site Stand-aloneOther conditions: Autosomal Dominant Alzheimers Disease, Early Onset Alzheimer Disease, Alzheimers DiseaseView official trial listing → -
Recruiting NCT NCT07571161
Donanemab (LY3002813) Trial in Chinese Participants With Cognitively Unimpaired (Preclinical) Alzheimer's Disease
Not yet reported Eli Lilly and Company 140 participants Est. completion 2030-04 30 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Recruiting NCT NCT07589595
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
Not yet reported Eli Lilly and Company 350 participants Est. completion 2028-08 72 sites Stand-aloneOther conditions: Cognitive Dysfunction, Lewy Body Disease, Synucleinopathies, AmyloidView official trial listing → -
Recruiting NCT NCT07602582
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
Not yet reported Eli Lilly and Company 550 participants Est. completion 2029-09 59 sites Stand-aloneOther conditions: Alzheimer Disease, Dementia, Plaque, AmyloidView official trial listing → -
Completed NCT NCT01837641
A Study of LY3002813 in Participants With Alzheimer's Disease
Not yet reported Eli Lilly and Company 63 participants Est. completion 2016-08-24 6 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT02624778
A Study of LY3002813 in Participants With Memory Damage Due to Alzheimer's Disease (AD) or AD
Not yet reported Eli Lilly and Company 61 participants Est. completion 2019-08-28 9 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT03367403
A Study of LY3002813 in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ)
Not yet reported Eli Lilly and Company 272 participants Est. completion 2021-09-21 61 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Active, not recruiting NCT NCT04437511
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)
Not yet reported Eli Lilly and Company 1736 participants Est. completion 2028-11 274 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT04640077
A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT)
Not yet reported Eli Lilly and Company 95 participants Est. completion 2024-02-27 27 sites Stand-aloneOther conditions: Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Cognitive ImpairmentView official trial listing → -
Active, not recruiting NCT NCT05026866
A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3)
Not yet reported Eli Lilly and Company 2996 participants Est. completion 2027-11 216 sites Stand-aloneOther conditions: Alzheimer DiseaseView official trial listing → -
Completed NCT NCT05108922
A Study of Donanemab (LY3002813) Compared With Aducanumab in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 4)
Not yet reported Eli Lilly and Company 148 participants Est. completion 2023-09-19 31 sites Stand-aloneOther conditions: Mild Cognitive Impairment (MCI), Alzheimer DiseaseView official trial listing → -
Active, not recruiting NCT NCT05508789
A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)
Not yet reported Eli Lilly and Company 1500 participants Est. completion 2028-07 141 sites Stand-aloneOther conditions: Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental DisordersView official trial listing → -
Completed NCT NCT05533411
A Study of Donanemab (LY3002813) in Healthy Chinese Participants
Not yet reported Eli Lilly and Company 36 participants Est. completion 2023-01-05 2 sites Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT05567159
A Study of Donanemab (LY3002813) in Healthy Participants
Not yet reported Eli Lilly and Company 42 participants Est. completion 2023-07-14 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Active, not recruiting NCT NCT05738486
A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)
Not yet reported Eli Lilly and Company 1175 participants Est. completion 2027-05 49 sites Stand-aloneOther conditions: Alzheimer's Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Neurodegenerative Diseases, Neurocognitive Disorders, Mental DisordersView official trial listing → -
Not yet recruiting NCT NCT06911944
Amyloid Lowering for Alzheimer's in Down's With Donanemab Investigation
Not yet reported Michael Rafii, MD, PhD 60 participants Est. completion 2028-12-31 Stand-aloneOther conditions: Down Syndrome (DS), Down Syndrome (Trisomy 21), Alzheimer Disease, Amyloid Beta ProteinView official trial listing → -
Enrolling by invitation NCT NCT07167966
Alzheimer's Tau Platform: Regimen A - AADvac1
Not yet reported Paul S. Aisen 450 participants Est. completion 2028-08-31 3 sites Stand-aloneOther conditions: Preclinical Alzheimer's Disease, Prodromal Alzheimer's Disease, Alzheimer DiseaseView official trial listing → -
Not yet recruiting NCT NCT07456462
Making Antibody Treatments More Effective in Early Alzheimer's Disease Using 3Tesla Magnetica Resonance
Not yet reported IRCCS San Raffaele 50 participants Est. completion 2029-05-01 1 site Stand-aloneOther conditions: Alzheimer Dementia (AD), Mild Cognitive Impairment (MCI)View official trial listing → -
Not yet recruiting NCT NCT07756294
Restoring Vascular and Insulin Function To Augment Anti-Amyloid Therapy in Alzheimer's Disease
Not yet reported Wake Forest University Health Sciences 30 participants Est. completion 2028-04 1 siteOther conditions: Alzheimer DiseaseView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Donanemab, Kisunla, LY3002813
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
