GLP-1 Market
LLY $1138.28 ▲ +2.0% NVO $43.45 ▲ +0.9% PFE $27.72 • 0.0% VKTX $31.53 ▼ -1.4% KLRA $13.75 ▼ -1.4% GPCR $38.44 ▼ -0.6% RHHBY $54.80 ▲ +3.9%
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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Dilaudid Product

Company
University of California, Davis
Mechanism
Mechanism not yet reported
Route
Injectable
Recruiting trials
28 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

28 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Sep 15, 2026

Find a Clinical Trial Near Me

See recruiting studies for Dilaudid Product and check eligibility with the study team.

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Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT03427736

    Anesthetics and Analgesics in Children

    Chi Dang Hornik 551 participants Est. completion 2027-09-09 13 sites
    Other conditions: Anesthesia, Pain
    View official trial listing →
  • Recruiting NCT NCT03481881

    Pharmacokinetics of Drugs Administered to Children

    Duke University 200 participants Est. completion 2033-08-14 1 site
    Other conditions: Pediatric ALL
    View official trial listing →
  • Recruiting NCT NCT03715517

    Spinal Anesthesia For Enhanced Recovery After Liver Surgery

    Not yet reported University of Manitoba 128 participants Est. completion 2031-12-31 1 site Stand-alone
    Other conditions: Hepatectomy, Pain, Postoperative, Liver Neoplasms
    View official trial listing →
  • Recruiting NCT NCT03893734

    Effect of Methadone and Hydromorphone on the QT Interval After Anesthesia and Surgery

    Not yet reported Endeavor Health 140 participants Est. completion 2020-12-23 1 site
    Other conditions: EKG-QT Prolongation
    View official trial listing →
  • Recruiting NCT NCT04044820

    Opioid Use Post-Discharge After Ambulatory Distal Arm Surgery

    Not yet reported University Health Network, Toronto 292 participants Est. completion 2026-12-31 1 site
    Other conditions: Opioid Use
    View official trial listing →
  • Recruiting NCT NCT04811209

    MCID and PASS for Acute Pain and Quality of Recovery After Orthopedic Surgery

    University Health Network, Toronto 300 participants Est. completion 2026-12-31 1 site
    Other conditions: Pain Management
    View official trial listing →
  • Recruiting NCT NCT05027919

    Assessing a Clinically-meaningful Opioid Withdrawal Phenotype

    Not yet reported University of Maryland, Baltimore 60 participants Est. completion 2027-02-28 1 site
    Substance use disorder Other conditions: Opioid Withdrawal, Opioid Craving
    View official trial listing →
  • Recruiting NCT NCT05722002

    Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

    Not yet reported University of Michigan 900 participants Est. completion 2027-08-31 8 sites
    Other conditions: Surgery, Pain, Postoperative
    View official trial listing →
  • Recruiting NCT NCT05842044

    NSAID Use After Robotic Partial Nephrectomy

    Not yet reported University of Miami 110 participants Est. completion 2026-09-30 1 site Stand-alone
    Other conditions: Kidney Cancer, Renal Cancer, Renal Neoplasm
    View official trial listing →
  • Recruiting NCT NCT06015165

    Outcomes for Anesthesiologist-Led Care of Analgesic Protocol in Anorectal Surgery

    Not yet reported China-Japan Friendship Hospital 216 participants Est. completion 2025-10-10 2 sites Stand-alone
    Other conditions: Postoperative Pain
    View official trial listing →
  • Recruiting NCT NCT06320041

    Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery

    Not yet reported The Fourth Affiliated Hospital of Zhejiang University School of Medicine 162 participants Est. completion 2026-12-31 1 site
    Other conditions: Postoperative Pain
    View official trial listing →
  • Recruiting NCT NCT06411795

    Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy

    Not yet reported Masonic Cancer Center, University of Minnesota 78 participants Est. completion 2028-01-01 1 site Stand-alone
    Other conditions: Duodenal Neoplasm, Pancreatic Neoplasm
    View official trial listing →
  • Recruiting NCT NCT06495632

    Scheduled or As Needed Pain Regimen?

    Not yet reported Cape Fear Valley Health System 90 participants Est. completion 2027-07-31 1 site Stand-alone
    Other conditions: Pain, Postoperative
    View official trial listing →
  • Recruiting NCT NCT06525740

    Methadone Versus Intrathecal Hydromorphone for Postoperative Pain Relief in Gynecologic Cancer Undergoing Surgery

    Not yet reported Mayo Clinic 140 participants Est. completion 2029-09-01 1 site Stand-alone
    Other conditions: Malignant Female Reproductive System Neoplasm
    View official trial listing →
  • Recruiting NCT NCT06559969

    IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia

    Not yet reported, Not yet reported University of Iowa 80 participants Est. completion 2027-03-30 1 site
    Other conditions: Laparotomy
    View official trial listing →
  • Recruiting NCT NCT06570577

    Opioid Sparing Effect of an ISP Nerve Block on Post-Op Pain Control in Posterior Cervical Spine Surgery

    Not yet reported Stony Brook University 60 participants Est. completion 2027-03 1 site
    Other conditions: Pain, Postoperative
    View official trial listing →
  • Recruiting NCT NCT06576830

    Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia

    Not yet reported Duke University 440 participants Est. completion 2029-06-01 1 site
    Other conditions: Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea, Sleep-Disordered Breathing
    View official trial listing →
  • Recruiting NCT NCT06617949

    Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications.

    Not yet reported Medical College of Wisconsin 20 participants Est. completion 2028-12 2 sites
    Substance use disorder
    View official trial listing →
  • Recruiting NCT NCT06671002

    Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial

    Not yet reported University of Michigan 900 participants Est. completion 2027-10-31 4 sites
    Other conditions: Surgery, Pain, Post Operative
    View official trial listing →
  • Recruiting NCT NCT06785571

    The Evaluation of the Effectiveness and Safety of Nalbuphine Hydrochloride Injection for Analgesia in ICU Patients: A Multicenter, Randomized, Single-blinded, Parallel, Two-step Trial

    Not yet reported, Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 204 participants Est. completion 2025-10-31 1 site
    Other conditions: Respiratory Insufficiency
    View official trial listing →
  • Recruiting NCT NCT06949059

    Intravenous Hydromorphone for the Treatment of Acute Pain

    Not yet reported, Not yet reported The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School 30 participants Est. completion 2027-12-31 1 site Stand-alone
    Other conditions: Acute Chest Pain
    View official trial listing →
  • Recruiting NCT NCT06962306

    Optimizing Perioperative Analgesia to Lower Pain Following Cleft Palate Surgery

    Not yet reported Duke University 60 participants Est. completion 2027-07-04 1 site
    Other conditions: Cleft Palate, Pain, Postoperative Care, Perioperative Care, Children
    View official trial listing →
  • Recruiting NCT NCT07348627

    Opioid-Sparing Joint Replacement

    Not yet reported Emory University 120 participants Est. completion 2028-08 1 site Stand-alone
    Other conditions: Pain Management, Opioid Consumption
    View official trial listing →
  • Recruiting NCT NCT07413731

    Neurophysiological Effects of Medication Tapering During Treatment With Spinal Cord Stimulation

    Brai²n 50 participants Est. completion 2027-04-03 1 site
    Other conditions: Persistent Spinal Pain Syndrome Type 2 (PSPS-T2), Lower Spine, Spinal Cord Sensitivity to Neurostimulation, Neurophysiological Sensitivity to Spinal Cord Stimulation
    View official trial listing →
  • Recruiting NCT NCT07430345

    Buprenorphine for Analgesia in Older Adults With Acute Fractures in the Emergency Department

    Not yet reported, Not yet reported The Cooper Health System 48 participants Est. completion 2027-01 1 site
    Other conditions: Fracture
    View official trial listing →
  • Recruiting NCT NCT07489625

    Hydromorphone With Electroacupuncture and Ear Acupoint Pressing for Refractory Cancer Pain

    Not yet reported Qinghai Red Cross Hospital 30 participants Est. completion 2028-12-31 1 site Stand-alone
    Other conditions: Refractory Cancer Pain, Cancer Pain
    View official trial listing →
  • Recruiting NCT NCT07510373

    Opioid Tapering After Hospital Discharge: Testing an Intervention to Improve Post-operative Opioid Prescribing

    Not yet reported Montefiore Medical Center 42 participants Est. completion 2028-04 1 site
    Other conditions: Opioid Tapering
    View official trial listing →
  • Recruiting NCT NCT07672301

    Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty

    Not yet reported, Not yet reported University of Chicago 150 participants Est. completion 2028-06 1 site
    Other conditions: Total Knee Arthroplasty (TKA)
    View official trial listing →
  • Completed NCT NCT00003115

    Epidural Hydromorphone Compared With Hydromorphone Infusion in Treating Patients With Prostate Cancer Undergoing Radical Prostatectomy

    Not yet reported Roswell Park Cancer Institute 40 participants Est. completion 2004-02 1 site
    Other conditions: Pain, Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00125801

    The Pain Pen for Breakthrough Cancer Pain

    Not yet reported Erasmus Medical Center 50 participants Est. completion 2008-05 1 site
    Other conditions: Neoplasms, Pain
    View official trial listing →
  • Completed NCT NCT00158236

    Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users

    Not yet reported National Institute on Drug Abuse (NIDA) 7 participants Est. completion 1998-03 1 site
    Other conditions: Opioid-Related Disorders
    View official trial listing →
  • Terminated NCT NCT00177060

    Topical Hydromorphone for Wound Healing

    Not yet reported, Not yet reported Hordinsky, Maria K., MD 50 participants Est. completion 2007-05 1 site
    Other conditions: Wound Healing
    View official trial listing →
  • Completed NCT NCT00195910

    Safety and Efficacy Study of Hydromorphone and Morphine

    Not yet reported Montefiore Medical Center 198 participants Est. completion 2005-01 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT00218309

    Effects of Pre-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals

    National Institute on Drug Abuse (NIDA) 16 participants Est. completion 2005-07 1 site
    Other conditions: Heroin Dependence, Opioid-Related Disorders
    View official trial listing →
  • Completed NCT NCT00218361

    Effects of Post-Session Supplemental Hydromorphone on Drug Seeking Behavior in Opioid Dependent Individuals

    Wayne State University 16 participants 1 site
    Other conditions: Heroin Dependence, Opioid-Related Disorders
    View official trial listing →
  • Completed NCT NCT00261495

    A Study of the Effectiveness and Safety of Sustained-release Hydromorphone (a Strong Opioid) in Patients With Chronic Noncancer Pain.

    Not yet reported Janssen Pharmaceutica N.V., Belgium 504 participants Est. completion 2008-04 52 sites Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT00295945

    Epidural Analgesia or Patient-Controlled Analgesia in Treating Patients Who Have Undergone Surgery for Gynecologic Cancer

    University of California, San Francisco 240 participants Est. completion 2009-12 1 site
    Other conditions: Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer, Pain, Perioperative/Postoperative Complications, Sarcoma
    View official trial listing →
  • Completed NCT NCT00305058

    Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain

    Not yet reported, Not yet reported Montefiore Medical Center 194 participants Est. completion 2007-03 1 site Stand-alone
    Other conditions: Acute Pain
    View official trial listing →
  • Completed NCT NCT00305110

    Safety of Hydromorphone in Adult Patients Presenting to the Emergency Department With Acute Severe Pain

    Not yet reported Montefiore Medical Center 298 participants Est. completion 2006-10 1 site Stand-alone
    Other conditions: Acute Pain
    View official trial listing →
  • Terminated NCT NCT00365898

    Efficacy and Safety of Hydromorphone Hydrochloride Extended-Release Compared to Placebo in Subjects With Persistent Pain

    Not yet reported Purdue Pharma LP 380 participants Est. completion 2005-07 14 sites
    Other conditions: Chronic Non-Malignant Pain
    View official trial listing →
  • Completed NCT NCT00380978

    Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery

    Not yet reported Northwestern University 1026 participants Est. completion 2008-09 1 site
    Other conditions: Labor Pain, Pregnancy
    View official trial listing →
  • Completed NCT NCT00385541

    Comparison of Side Effects of Morphine and Hydromorphone Patient-Controlled Analgesia (PCA)

    Not yet reported Columbia University 50 participants Est. completion 2007-10 1 site
    Other conditions: Post Operative Pain
    View official trial listing →
  • Completed NCT NCT00398788

    A Study on Efficacy (Effectiveness), Safety, and Impact on Quality of Life Measures of Dilaudid CR (Controlled Release);, Hydromorphone HCl in Patients With Chronic Low Back Pain

    Not yet reported Alza Corporation, DE, USA 207 participants Est. completion 2001-11
    Other conditions: Low Back Pain
    View official trial listing →
  • Completed NCT NCT00398957

    An Open-Label Evaluation of the Dose Proportionality of OROS� Hydromorphone HCL Tablets 8mg, 16mg, 32mg, 64mg

    Not yet reported Alza Corporation, DE, USA 32 participants Est. completion 1998-09
    Other conditions: Analgesia
    View official trial listing →
  • Completed NCT NCT00399048

    An Effectiveness, Safety and Quality of Life Measures With Hydromorphone HCL, Dilaudid CR (Controlled Release)

    Not yet reported Alza Corporation, DE, USA 140 participants Est. completion 2001-05
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT00399295

    An Open-Label Evaluation of the Independent Effects of Coadministration of a High-Fat Meal and Naltrexone Blockade on the Pharmacokinetic Profile of Dilaudid OROS (Hydromorphone HCI) 16mg

    Not yet reported Alza Corporation, DE, USA 30 participants Est. completion 1997-06
    Other conditions: Analgesia
    View official trial listing →
  • Completed NCT NCT00410540

    A Study of OROS Hydromorphone HCL vs Morphine in Cancer Pain Patients.

    Not yet reported Alza Corporation, DE, USA 202 participants Est. completion 2001-05
    Other conditions: Pain, Analgesics, Opioid
    View official trial listing →
  • Completed NCT NCT00410644

    A Repeated-Dose Evaluation of a Pain Relieving Drug Use and Safety of OROS Hydromorphone HCI in Patients With Chronic Non-Malignant Pain

    Not yet reported Alza Corporation, DE, USA 463 participants Est. completion 1999-02
    Other conditions: Pain, Analgesics, Opioid
    View official trial listing →
  • Completed NCT NCT00410748

    Safety and Tolerability of Long-Term Administration of Hydromorphone HCI CR (Controlled Release)

    Not yet reported Alza Corporation, DE, USA 388 participants Est. completion 2000-06
    Other conditions: Pain, Analgesics, Opioid
    View official trial listing →
  • Completed NCT NCT00410787

    Safety and Tolerability of Long-term Administration of OROS Hydromorphone HCI (Slow Release) in Cancer Pain

    Not yet reported Alza Corporation, DE, USA 68 participants Est. completion 2002-04
    Other conditions: Analgesics, Opioid, Pain
    View official trial listing →
  • Completed NCT NCT00410878

    A Repeated Dose Study of the Metabolism and Action Evaluation of OROS Hydromorphone HCI (Slow Release) Tablets in Patients With Chronic Pain

    Not yet reported Alza Corporation, DE, USA 22 participants Est. completion 1999-08
    Other conditions: Pain, Analgesics, Opioid
    View official trial listing →
  • Completed NCT NCT00410943

    Study of the Effectiveness and Tolerability of OROS Hydromorphone HCI SR(Slow-release) Tablets and Immediate-Release Hydromorphone Tablets in Patients With Chronic Pain

    Not yet reported Alza Corporation, DE, USA 169 participants Est. completion 1999-06
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT00411034

    A Repeated-Dose Evaluation of Use of a Pain Relieving Drug and Safety of OROS Hydromorphone HCI in Patients With Chronic Cancer Pain

    Not yet reported Alza Corporation, DE, USA 463 participants Est. completion 1999-09
    Other conditions: Analgesics, Opioid, Pain
    View official trial listing →
  • Completed NCT NCT00411164

    A Study to Evaluate the Effectiveness and Safety of Slow Release Hydromorphone HCL for Treatment of Patients With Osteoarthritis

    Not yet reported Alza Corporation, DE, USA 990 participants Est. completion 2005-05
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT00411268

    Safety, Effectiveness, and Impact on Quality of Life on Long-Term Administration of OROS Hydromorphone Slow-Release in Patients With Chronic Low Back Pain

    Not yet reported Alza Corporation, DE, USA 207 participants Est. completion 2001-06
    Other conditions: Low Back Pain
    View official trial listing →
  • Completed NCT NCT00411307

    A Randomized, Open-Label, Single-Dose, Small Study to Evaluate the Safety and Effectiveness of Hydromorphone in Patients With Short Term, Moderate to Severe Postoperative Pain

    Not yet reported Alza Corporation, DE, USA 50 participants Est. completion 2001-10
    Other conditions: Pain, Postoperative, Orthopedic Procedures, Analgesia
    View official trial listing →
  • Completed NCT NCT00413582

    Pain Management for Pectus Excavatum Repair

    Not yet reported Children's Mercy Hospital Kansas City 110 participants Est. completion 2010-10 1 site Stand-alone
    Other conditions: Postoperative Pain
    View official trial listing →
  • Completed NCT NCT00465647

    An Open-label Study of Hydromorphone Oral Solution in Subjects Aged 28 Days to 16 Years for Postoperative Pain

    Not yet reported Purdue Pharma LP 116 participants Est. completion 2010-04 14 sites Stand-alone
    Other conditions: Postoperative Pain
    View official trial listing →
  • Withdrawn NCT NCT00474110

    Ketamine and Hydromorphone for Patient Controlled Pain Relief in Children's Mucositis

    Not yet reported University of British Columbia Est. completion 2011-12 1 site Stand-alone
    Other conditions: Mucositis
    View official trial listing →
  • Completed NCT NCT00499746

    The Discriminative Effects of Tramadol in Humans

    Not yet reported, Not yet reported National Institute on Drug Abuse (NIDA) 20 participants Est. completion 2011-08 1 site
    Other conditions: Opioid Abuse, Opioid Addiction, Stimulant Abuse, Stimulant Addiction
    View official trial listing →
  • Completed NCT NCT00547664

    Efficacy of Hylenex in the Treatment of Pain Among Hospice Patients

    Not yet reported HPC Healthcare, Inc. 88 participants Est. completion 2010-10 3 sites Stand-alone
    Other conditions: Pain Management
    View official trial listing →
  • Completed NCT NCT00549042

    Study to Test the Effectiveness of Controlled-Release OROS® Hydromorphone HCl Compared to Placebo in Patients With Chronic Low Back Pain

    Not yet reported Mallinckrodt 459 participants Est. completion 2009-01 Stand-alone
    Other conditions: Chronic Low Back Pain
    View official trial listing →
  • Completed NCT NCT00588159

    Preoperative Gabapentin for Acute and Chronic Post-thoracotomy Analgesia

    Not yet reported Michelle Kinney 146 participants Est. completion 2010-03 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT00600158

    Effects of Intravenous Local Anesthetic on Bowel Function After Colectomy

    Not yet reported University of Virginia 45 participants Est. completion 2006-07 1 site
    Other conditions: Postoperative Ileus
    View official trial listing →
  • Completed NCT NCT00627367

    Protocolized vs Nonprotocolized Treatment of Adult ED Patients With Acute Severe Pain

    Not yet reported Montefiore Medical Center 224 participants Est. completion 2008-03 1 site Stand-alone
    Other conditions: Acute Pain
    View official trial listing →
  • Completed NCT NCT00631319

    A Double-blind Study of Controlled Release OROS Hydromorphone Compared to Placebo in Patients With Chronic Osteoarthritis (OA) Pain

    Not yet reported Mallinckrodt 343 participants Est. completion 2009-06 Stand-alone
    Other conditions: Chronic Pain
    View official trial listing →
  • Completed NCT NCT00644111

    Post-operative Epidural Analgesia After Minimally Invasive Lumbar Decompression and Fusion

    Not yet reported University Health Network, Toronto 32 participants Est. completion 2011-07 1 site
    Other conditions: Low Back Pain
    View official trial listing →
  • Completed NCT NCT00682435

    Safety Study of Intravenous Hydromorphone Using Incremental 1mg Doses up to 2mg for Adult ED Patients

    Not yet reported Montefiore Medical Center 230 participants Est. completion 2007-11 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT00710086

    Intravenous Remifentanil for Labor Analgesia

    Not yet reported Nanjing Medical University 1000 participants Est. completion 2009-09 1 site
    Other conditions: Labor Pain
    View official trial listing →
  • Completed NCT NCT00766831

    An Efficacy and Safety Study of Hydromorphone Oral Osmotic System (OROS) in Korean Participants With Cancer Pain

    Not yet reported Janssen Korea, Ltd., Korea 190 participants Est. completion 2010-06 Stand-alone
    Other conditions: Cancer Pain
    View official trial listing →
  • Completed NCT NCT00790179

    Continuous Lumbar Plexus Block for Postoperative Pain Control After Total Hip Arthroplasty

    Not yet reported Northwell Health 225 participants Est. completion 2007-03
    Other conditions: Postoperative Pain
    View official trial listing →
  • Terminated NCT NCT00803283

    A Study to Compare Safety and Efficacy of Osmotic Release Oral Syytem (OROS) Hydromorphone Hydrochloride (HCl) With Morphine Sustain Release (SR) in Participants With Cancer Pain

    Not yet reported Johnson & Johnson Taiwan Ltd 2 participants Est. completion 2008-12 Stand-alone
    Other conditions: Cancer Pain
    View official trial listing →
  • Status unknown NCT NCT00822614

    Safety of Fentanyl TAIFUN Treatment

    Not yet reported Akela Pharma, Inc. 500 participants Est. completion 2010-01 1 site
    Other conditions: Breakthrough Cancer Pain
    View official trial listing →
  • Completed NCT NCT00825370

    Protocolized vs Discretionary Use of Opioids in Acute Pain

    Not yet reported Montefiore Medical Center 350 participants Est. completion 2009-05 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT00853554

    Fasting Study of Hydromorphone Hydrochloride 8 mg Tablets and Dilaudid 8 mg Tablets

    Not yet reported Mallinckrodt 24 participants Est. completion 2002-12 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00955110

    Study to Compare Oxymorphone Extended-Release (Opana ER) Versus Oxycodone Controlled-Release (Oxycontin)

    Not yet reported Endo USA Inc., a Keenova Therapeutics Company 78 participants Est. completion 2009-09 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Completed NCT NCT00980798

    Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee

    Not yet reported Janssen-Cilag International NV 288 participants Est. completion 2008-11 12 sites Stand-alone
    Osteoarthritis Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT00982800

    Does Postoperative Gabapentin Reduce Pain, Opioid Consumption and Anxiety and Have a Positive Effect on Health Related Quality of Life After Radical Prostatectomy?

    Not yet reported Sunnybrook Health Sciences Centre 60 participants Est. completion 2010-01 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00982891

    Palliation of Dyspnea in Advanced Chronic Obstructive Pulmonary Disease (COPD)

    Not yet reported, Not yet reported Nova Scotia Health Authority 45 participants Est. completion 2012-06 3 sites
    Other conditions: Chronic Obstructive Pulmonary Disease (COPD)
    View official trial listing →
  • Completed NCT NCT00992576

    Optimisation of Hydromorphone - Naloxone Ratio for the Treatment of Pain

    Not yet reported, Not yet reported Mundipharma Research GmbH & Co KG 600 participants Est. completion 2012-01 14 sites
    Other conditions: Constipation
    View official trial listing →
  • Terminated NCT NCT00999245

    THE IMPROVE TRIAL: Improving Pain Management and Outcomes With Various Strategies of Patient-Controlled Analgesia (PCA)

    Not yet reported Carelon Research 38 participants Est. completion 2010-06 28 sites
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Completed NCT NCT01006356

    An Efficacy and Safety Study of Hydromorphone Hydrochloride (HCl) Oral Osmotic System (OROS) in the Reduction of Breakthrough Pain Medication Frequency in Participants With Cancer

    Not yet reported Janssen Korea, Ltd., Korea 141 participants Est. completion 2009-08 Stand-alone
    Other conditions: Cancer, Pain
    View official trial listing →
  • Terminated NCT NCT01019681

    Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb Ischemia

    Not yet reported Richard Burt, MD 1 participants Est. completion 2014-01 1 site
    Other conditions: Critical Limb Ischemia
    View official trial listing →
  • Withdrawn NCT NCT01108562

    Treatment of Postoperative Pain After Total Hip Arthroplasty Using Intravenous Lidocaine Infusion

    Not yet reported, Not yet reported Loma Linda University
    Other conditions: Postoperative Pain Management After Total Hip Arthroplasty
    View official trial listing →
  • Withdrawn NCT NCT01123486

    Hydromorphone Pharmacokinetic-Pharmacodynamic Fingerprint

    Not yet reported Northwestern University Est. completion 2015-01 1 site Stand-alone
    Other conditions: Pain, Ventilatory Depression
    View official trial listing →
  • Withdrawn NCT NCT01125059

    Methadone Versus Placebo in Spine Fusion

    Not yet reported Northwestern University Est. completion 2014-01 1 site
    Other conditions: Postoperative Pain
    View official trial listing →
  • Completed NCT NCT01172782

    The Analgesic Effect of Intrathecal Hydromorphone Injection on Spinal Anesthesia

    Not yet reported Korea University Anam Hospital 60 participants Est. completion 2010-07
    Other conditions: Pain Measurement, Visual Analog Pain Scale
    View official trial listing →
  • Completed NCT NCT01205126

    An Efficacy and Safety Study of Oral Osmotic Therapeutic System (OROS) Hydromorphone Hydrochloride (HCl) in Participants With Cancer Related Pain

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 260 participants Est. completion 2011-02 12 sites Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01207596

    Evaluating the Efficacy and Safety of Extended Release Hydromorphone (Exalgo) in Patients With Neuropathic Pain

    Not yet reported International Clinical Research Institute 30 participants Est. completion 2011-09 1 site
    Other conditions: Neuropathic Pain
    View official trial listing →
  • Completed NCT NCT01218984

    ALK21-004: Single-dose Opiate Challenge of Medisorb® Naltrexone (VIVITROL®) in Adults Who Use Opioids

    Not yet reported Alkermes, Inc. 27 participants Est. completion 2003-05 Stand-alone
    Other conditions: Opiate Dependence
    View official trial listing →
  • Completed NCT NCT01273454

    An Observational Study to Investigate Clinical Usefulness of OROS Hydromorphone in Korean Cancer Patients

    Janssen Korea, Ltd., Korea 648 participants Est. completion 2009-12
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01311895

    Clinical Trial Comparing Two Protocols Using Intravenous (IV) Hydromorphone

    Not yet reported Montefiore Medical Center 350 participants Est. completion 2011-11 1 site Stand-alone
    Other conditions: Acute Pain
    View official trial listing →
  • Completed NCT NCT01335542

    Analgesia After Total Knee Arthroplasty: Peri-Articular Injection Versus Epidural + Femoral Nerve Blockade

    Not yet reported Hospital for Special Surgery, New York 91 participants Est. completion 2011-09 1 site
    Other conditions: Readiness to Discharge
    View official trial listing →
  • Completed NCT NCT01371903

    The Effects of Patient Features on Opioid Induced End-Tidal CO2

    Albany Medical College 278 participants Est. completion 2012-11 1 site
    Other conditions: Opioid Use During Medical Care
    View official trial listing →
  • Completed NCT NCT01394445

    Pilot Study of Physostigmine-Enhanced Opioid Analgesia

    Not yet reported Medical University of Graz 20 participants Est. completion 2011-12 1 site
    Other conditions: Postoperative Pain
    View official trial listing →
  • Completed NCT NCT01429285

    Safety and Efficacy of Intravenous Hydromorphone in Elderly Emergency Department Patients With Acute Severe Pain

    Not yet reported Montefiore Medical Center 350 participants Est. completion 2012-06 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01429298

    Comparing Intravenous Hydromorphone to Usual Care

    Not yet reported Montefiore Medical Center 350 participants Est. completion 2010-11 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01442818

    Patient Satisfaction and Pain Control Following Reconstructive Vaginal Surgery

    Not yet reported TriHealth Inc. 54 participants Est. completion 2012-10 1 site
    Other conditions: Post Operative Pain
    View official trial listing →
  • Completed NCT NCT01447212

    Study to Assess Longer-term Opioid Medication Effectiveness (SALOME)

    Not yet reported University of British Columbia 202 participants Est. completion 2016-02 1 site Stand-alone
    Other conditions: Opioid Dependence, Heroin Dependence
    View official trial listing →
  • Completed NCT NCT01447888

    Perioperative Pain Management In Spine Surgery Patients: Part I

    Not yet reported Allina Health System 100 participants Est. completion 2014-04 1 site
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01455519

    True Functional Restoration and Analgesia in Non-Radicular Low Back Pain

    Not yet reported Shirley Ryan AbilityLab 51 participants Est. completion 2014-12 1 site
    Other conditions: Low Back Pain
    View official trial listing →
  • Completed NCT NCT01487512

    Effect of Dose on the Pharmacokinetics of OROS Hydromorphone Under Fasted Conditions in Healthy Taiwanese Participants

    Not yet reported Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 29 participants Est. completion 2011-07 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT01487564

    Pharmacokinetic Profile of OROS Hydromorphone in Healthy Taiwanese Participants With Different Genotypes for the UGT2B7 Gene

    Not yet reported Janssen Research & Development, LLC 29 participants Est. completion 2012-01 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT01490268

    Pain Therapy After Elective Cardiac Surgery

    Not yet reported University of Erlangen-Nürnberg Medical School 50 participants Est. completion 2012-09 1 site
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01517295

    Pharmacokinetic Study of Hydrocodone/APAP in Chronic Pain Patients

    Not yet reported NEMA Research, Inc. 30 participants Est. completion 2012-09 2 sites
    Other conditions: Chronic Pain
    View official trial listing →
  • Completed NCT NCT01532895

    Clinical Usefulness and Quality of Life of OROS Hydromorphone in Patients Who Have Not Been Treated With a Strong Opioid

    Janssen Korea, Ltd., Korea 400 participants Est. completion 2012-10 11 sites
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01546948

    Intraoperative Opioids and Postoperative Recovery After Hepatobiliary or Foregut Surgery

    Not yet reported Endeavor Health 60 participants Est. completion 2018-06 1 site
    Other conditions: Postoperative Pain
    View official trial listing →
  • Completed NCT NCT01568437

    Transversus Abdominis Plane (TAP) Block in Laparoscopic Gastric-bypass Surgery

    Not yet reported University Health Network, Toronto 70 participants Est. completion 2013-03 1 site Stand-alone
    Other conditions: Gastric-bypass Surgery, Opioid Consumption, Obesity
    View official trial listing →
  • Completed NCT NCT01582490

    Study of EXPAREL in Patients Undergoing Breast Augmentation

    Not yet reported Pacira Pharmaceuticals, Inc 19 participants Est. completion 2012-11 1 site Stand-alone
    Other conditions: Mammoplasty, Postoperative Pain
    View official trial listing →
  • Completed NCT NCT01591382

    Efficacy Study of Ketamine for Postoperative Pain in Opioid Dependent Patients

    Not yet reported Brigham and Women's Hospital 64 participants Est. completion 2012-06 1 site
    Other conditions: Postoperative Pain
    View official trial listing →
  • Completed NCT NCT01598506

    Intrathecal Hydromorphone for Labor Analgesia

    Not yet reported Emory University 22 participants Est. completion 2014-02 1 site Stand-alone
    Other conditions: Labor Pain
    View official trial listing →
  • Completed NCT NCT01598545

    Hydromorphone and C-section

    Not yet reported Emory University 20 participants Est. completion 2014-09 1 site Stand-alone
    Other conditions: Postoperative Pain
    View official trial listing →
  • Completed NCT NCT01621100

    Study to Evaluate Effectiveness and Tolerability of OROS Hydromorphone for Cancer Pain Treatment in Korean Patients

    Not yet reported Janssen Korea, Ltd., Korea 106 participants Est. completion 2012-09 6 sites Stand-alone
    Other conditions: Cancer Pain
    View official trial listing →
  • Completed NCT NCT01642030

    Study of the Treatment of Experimental Pain in Opioid Dependent Persons on Methadone or Buprenorphine Maintenance

    Not yet reported Johns Hopkins University 132 participants Est. completion 2017-07 1 site
    Other conditions: Opioid Dependence, Pain, Addiction
    View official trial listing →
  • Terminated NCT NCT01648699

    Safety and Efficacy Study of Osmotic Release Oral System (OROS) Hydromorphone in Participants With Cancer Pain

    Not yet reported Janssen Pharmaceutica 20 participants Est. completion 2010-09 Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01675778

    Association Between Body Size and Response to Hydromorphone in ED

    Not yet reported Albert Einstein College of Medicine 174 participants Est. completion 2012-12 2 sites
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01709721

    Safety and Efficacy Study of Hydromorphone Hydrochloride by Intrathecal Administration

    Not yet reported Piramal Critical Care, Ltd. 153 participants Est. completion 2018-02 1 site Stand-alone
    Other conditions: Management of Chronic Pain
    View official trial listing →
  • Completed NCT NCT01709747

    Single-arm Study to Assess the Safety of Hydromorphone Hydrochloride by Intrathecal Administration

    Not yet reported Piramal Critical Care, Ltd. 364 participants Est. completion 2018-02 1 site Stand-alone
    Other conditions: Chronic Pain
    View official trial listing →
  • Completed NCT NCT01715701

    Efficacy of Paravertebral Nerve Blockade to Reduce Pain Following Thoracoscopy

    Not yet reported Centre hospitalier de l'Université de Montréal (CHUM) 60 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: Postoperative Pain
    View official trial listing →
  • Completed NCT NCT01735851

    Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery

    Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 70 participants Est. completion 2014-12 1 site
    Other conditions: Postoperative Pain
    View official trial listing →
  • Terminated NCT NCT01784991

    Study of Respiratory Depression When Using a Hydromorphone Pain Protocol

    Not yet reported Albert Einstein Healthcare Network 116 participants Est. completion 2014-04-16 1 site
    Other conditions: Pain, Respiratory Depression
    View official trial listing →
  • Terminated NCT NCT01812759

    Fentanyl for Breakthrough Pain in the Emergency Department

    Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2014-10-22 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01824524

    A Pharmacokinetic and Safety Study of Osmotic Release Oral System (OROS) Hydromorphone in Non-Opioid Tolerant Chinese Participants With Cancer

    Not yet reported Xian-Janssen Pharmaceutical Ltd. 12 participants Est. completion 2012-08 2 sites Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01848951

    Comparison of Epidural and TAP Block in Abdominal Surgery

    University of Nebraska 72 participants Est. completion 2016-12-01 1 site
    Other conditions: Acute Pain, Surgery, Regional Anesthesia
    View official trial listing →
  • Completed NCT NCT01866254

    Use of Intrathecal Hydromorphone in Elective Cesarean Deliveries

    Not yet reported Grace Shih, MD 45 participants Est. completion 2018-10-22 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT01892709

    Titration of Intravenous Hydromorphone

    Not yet reported Montefiore Medical Center 215 participants Est. completion 2014-04 1 site Stand-alone
    Other conditions: Acute Severe Pain
    View official trial listing →
  • Completed NCT NCT01908491

    Comparison of IV PCA and Wound Infusion After Repair of Pectus Excavatum

    Not yet reported The Catholic University of Korea 80 participants Est. completion 2013-10 1 site
    Other conditions: Pain, Side Effects
    View official trial listing →
  • Withdrawn NCT NCT01932554

    Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain Crisis

    Not yet reported St. Louis University Est. completion 2015-03 1 site Stand-alone
    Other conditions: Sickle Cell Disease, Hb-SS Disease With Vasoocclusive Pain, Hemoglobin SS Disease With Vasoocclusive Crisis, Other Sickle Cell Disease With Vaso-Occlusive Pain, Hemoglobin SS Disease With Crisis
    View official trial listing →
  • Completed NCT NCT01938079

    Pharmacokinetic Alterations During ECMO

    Not yet reported Columbia University 20 participants Est. completion 2015-08 1 site Stand-alone
    Other conditions: Acute Respiratory Failure
    View official trial listing →
  • Terminated NCT NCT01943565

    Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding Study

    Not yet reported Brigham and Women's Hospital 29 participants Est. completion 2016-08 1 site
    Other conditions: Healthy, Pain, Pregnancy
    View official trial listing →
  • Completed NCT NCT01946555

    Prospective Longitudinal Observational Study to Evaluate the Clinical Characteristics and Opioids Treatments in Patients With Breakthrough Cancer Pain

    Mario Negri Institute for Pharmacological Research 150 participants Est. completion 2015-12 11 sites
    Other conditions: Tumor, Cancer Pain, Breakthrough Cancer Pain, Neuropathic Pain
    View official trial listing →
  • Terminated NCT NCT01986946

    Epidural Analgesia Versus IV Analgesia in Lumbar Spine Fusions

    Not yet reported Duke University 17 participants Est. completion 2015-09 1 site
    Other conditions: Lumbar Spine Fusion, Pain, Back Pain
    View official trial listing →
  • Completed NCT NCT01993238

    Evaluation of Procedural Analgesia for Liposonix Treatment

    Not yet reported Solta Medical 11 participants Est. completion 2014-01 1 site Stand-alone
    Other conditions: Body Contouring
    View official trial listing →
  • Completed NCT NCT02009722

    Intrathecal Opioids for Pain Control After Cesarean Delivery: Determining the Optimal Dose

    Not yet reported Mayo Clinic 84 participants Est. completion 2015-04 1 site
    Other conditions: Analgesia, Obstetrical, Cesarean Section
    View official trial listing →
  • Completed NCT NCT02035709

    Postoperative Pain Therapy With Hydromorphone Using TCI-PCA

    Not yet reported University of Erlangen-Nürnberg Medical School 50 participants Est. completion 2015-04 2 sites
    Other conditions: Postoperative Pain
    View official trial listing →
  • Completed NCT NCT02044094

    Multiple Dose Study of Blockade of Opioid Effects by Injections of Buprenorphine in Participants With Opioid Disorder

    Not yet reported Indivior Inc. 39 participants Est. completion 2014-07 1 site Stand-alone
    Substance use disorder
    View official trial listing →
  • Terminated NCT NCT02056301

    A Comparison Trial Between PCA and Epidural Analgesia for Pectus Excavatum Repair

    Not yet reported Baylor College of Medicine 62 participants Est. completion 2019-10 1 site
    Other conditions: Pectus Excavatum
    View official trial listing →
  • Terminated NCT NCT02062879

    Ketamine Patient-Controlled Analgesia for Acute Pain

    Not yet reported University of Cincinnati 20 participants Est. completion 2016-06 1 site
    Other conditions: Acute Pain, Multiple Trauma, Fractures
    View official trial listing →
  • Completed NCT NCT02067520

    Intrathecal Hydromorphone for Cesarean Section

    Not yet reported Thomas Jefferson University 54 participants Est. completion 2015-06 1 site
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT02073435

    A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation

    Northwestern University 177 participants Est. completion 2018-04 4 sites
    Other conditions: Liver Diseases, Hepatocellular Cancer, Endstage Liver Disease, Liver Cirrhosis
    View official trial listing →
  • Status unknown NCT NCT02084355

    Study of Opioid Rotation Versus Opioid Escalation in Patients With Moderate to Severe Cancer Pain

    Not yet reported Gyeongsang National University Hospital 136 participants Est. completion 2016-01 1 site Stand-alone
    Other conditions: Cancer, Pain
    View official trial listing →
  • Completed NCT NCT02086123

    Randomized Study Comparing the Use of Epidural Analgesia to Intravenous Narcotics for Laparoscopic Colorectal Resection.

    Not yet reported University of California, Irvine 87 participants Est. completion 2015-04 1 site
    Other conditions: Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT02096003

    Intrathecal Hydromorphone for Pain Control After Cesarean Section

    Not yet reported Icahn School of Medicine at Mount Sinai 80 participants Est. completion 2017-05-05 1 site Stand-alone
    Other conditions: Pain, Cesarean Section
    View official trial listing →
  • Completed NCT NCT02107339

    Methadone and Hydromorphone For Spinal Surgery

    Not yet reported Endeavor Health 120 participants Est. completion 2017-09 1 site
    Other conditions: Hydromorphone Use, Acute Postoperative Pain, Patient Satisfaction, Chronic Persistent Surgical Pain
    View official trial listing →
  • Completed NCT NCT02110719

    Decreasing Narcotics in Advanced Pelvic Surgery

    Not yet reported Hartford Hospital 138 participants Est. completion 2016-06 1 site
    Other conditions: Narcotic Use, Pain, Constipation, Nausea
    View official trial listing →
  • Completed NCT NCT02111746

    PAIN - Postoperative Analgesia INvestigation

    Not yet reported The University of Texas Health Science Center, Houston 350 participants Est. completion 2017-06-30 1 site Stand-alone
    Other conditions: Postoperative Pain
    View official trial listing →
  • Status unknown NCT NCT02136784

    Analgesic Response to Opioid Analgesics in Buprenorphine-Maintained Individuals

    Not yet reported University of California, Los Angeles 12 participants Est. completion 2014-12 1 site Stand-alone
    Other conditions: Analgesic Response
    View official trial listing →
  • Terminated NCT NCT02164929

    Comparison Study of Transversus Abdominal Plane, Paravertebral and Epidural Blocks in Laparoscopic Colectomy

    Not yet reported Duke University 17 participants Est. completion 2015-03 1 site
    Other conditions: Laparoscopic Colorectal Resection
    View official trial listing →
  • Completed NCT NCT02178553

    Study of Exparel Versus Epidural for Pain Control After Thoracotomy

    Not yet reported Mayo Clinic 102 participants Est. completion 2019-01-25 1 site
    Other conditions: Pain Following Thoracotomy Surgery
    View official trial listing →
  • Completed NCT NCT02190903

    A Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia

    Not yet reported University of Pennsylvania 15 participants Est. completion 2015-04 1 site
    Other conditions: Postoperative Complications, Hip Fracture, Delirium
    View official trial listing →
  • Terminated NCT NCT02192879

    TEA vs. PVB vs. PCA in Liver Resection Surgery

    Not yet reported Duke University 10 participants Est. completion 2016-05 1 site
    Other conditions: Pain Management Strategies in Liver Resection Surgery
    View official trial listing →
  • Completed NCT NCT02205983

    The Effects of Hydromorphone on Responses to Verbal Tasks

    Not yet reported University of Chicago 50 participants Est. completion 2016-09 1 site Stand-alone
    Other conditions: Healthy
    View official trial listing →
  • Terminated NCT NCT02219581

    Steroids in Total Knee Arthroplasty

    Not yet reported Thomas L Bradbury 1 participants Est. completion 2015-12-01 1 site
    Osteoarthritis Other conditions: Postoperative Pain, Inflammation
    View official trial listing →
  • Completed NCT NCT02222246

    Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease

    Not yet reported Duke University 106 participants Est. completion 2016-06-30 2 sites Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Completed NCT NCT02223377

    Satisfactory Analgesia Minimal Emesis in Day Surgeries

    Not yet reported McMaster University 402 participants Est. completion 2019-03 2 sites
    Other conditions: Pain, Post Operative Nausea and Vomiting
    View official trial listing →
  • Terminated NCT NCT02247648

    Efficacy of Extended-release, Once Daily Tramadol for Post Operative Analgesia in Shoulder Arthroscopy

    Not yet reported Centre hospitalier de l'Université de Montréal (CHUM) 100 participants Est. completion 2017-12 1 site
    Other conditions: Pain, Vertigo, Nausea, Pruritus
    View official trial listing →
  • Completed NCT NCT02277080

    The Immune and Endocrine Systems in Chronic Non-cancer Patients Treated With Opioids

    Rigshospitalet, Denmark 82 participants Est. completion 2022-12-28
    Other conditions: Pain, Opioids, Immune System, Endocrine System, Quality of Life
    View official trial listing →
  • Terminated NCT NCT02277782

    Intrathecal Hydromorphone for Labor Analgesia

    Not yet reported Brigham and Women's Hospital 21 participants Est. completion 2019-12-31 1 site Stand-alone
    Other conditions: Pregnancy
    View official trial listing →
  • Completed NCT NCT02295124

    Nausea in Patients Receiving Hydromorphone vs Oxycodone After Total Hip Replacement Surgery

    Not yet reported University Health Network, Toronto 200 participants Est. completion 2016-01 1 site
    Other conditions: Nausea
    View official trial listing →
  • Terminated NCT NCT02321319

    Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain Patients

    Not yet reported Mallinckrodt 5 participants Est. completion 2019-02-04 3 sites Stand-alone
    Other conditions: Chronic Pain
    View official trial listing →
  • Completed NCT NCT02351700

    Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors

    Not yet reported St. Joseph's Hospital and Medical Center, Phoenix 62 participants Est. completion 2016-04-01 1 site
    Other conditions: Pituitary Tumor, Pain
    View official trial listing →
  • Completed NCT NCT02356198

    Exparel Transversus Abdominis Plane Block vs Intrathecal Analgesia In Colorectal Surgery

    Not yet reported Mayo Clinic 209 participants Est. completion 2017-10 1 site
    Other conditions: Conditions Requiring Colorectal Surgery
    View official trial listing →
  • Terminated NCT NCT02358850

    Post-tonsillectomy Pain Control in Adults

    Not yet reported University of Nebraska 27 participants Est. completion 2019-01-24 1 site
    Other conditions: Pain, Postoperative, Postoperative Nausea and Vomiting, Postoperative Hemorrhage, Body Weight Changes
    View official trial listing →
  • Completed NCT NCT02360371

    A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans

    Not yet reported Johns Hopkins University 100 participants Est. completion 2021-05 1 site Stand-alone
    Other conditions: Opioid Sensitivity, Individual Difference, Abuse Opioids
    View official trial listing →
  • Completed NCT NCT02361775

    Paravertebral Catheters for VATS Procedures

    Not yet reported University of Minnesota 50 participants Est. completion 2014-10
    Other conditions: Acute Pain
    View official trial listing →
  • Completed NCT NCT02372591

    Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain

    Not yet reported Johns Hopkins University 14 participants Est. completion 2017-06 1 site
    Other conditions: Opioid-Related Disorders, Chronic Pain
    View official trial listing →
  • Completed NCT NCT02389829

    Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute Migraine

    Not yet reported Montefiore Medical Center 127 participants Est. completion 2016-10 1 site
    Other conditions: Migraine
    View official trial listing →
  • Completed NCT NCT02423876

    Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery

    Not yet reported University of Wisconsin, Madison 104 participants Est. completion 2022-01-03 1 site Stand-alone
    Other conditions: Intraoperative Complication, Malignant Female Reproductive System Neoplasm, Pain
    View official trial listing →
  • Completed NCT NCT02437669

    Intranasal Hydromorphone for the Treatment of Acute Pain in Children: A Pilot Study.

    Not yet reported Columbia University 35 participants Est. completion 2018-04 1 site Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT02449369

    Intra-Venous Acetaminophen and Muscle Relaxants After Total Knee

    Not yet reported AdventHealth 180 participants Est. completion 2016-09 1 site Stand-alone
    Other conditions: Unilateral Knee Arthroplasty
    View official trial listing →
  • Completed NCT NCT02459964

    Compare Fentanyl Nasal Spray With Intravenous Opioids to Treat Severe Pain

    Not yet reported M.D. Anderson Cancer Center 84 participants Est. completion 2020-06-21 1 site
    Other conditions: Advanced Cancers, Pain
    View official trial listing →
  • Completed NCT NCT02461056

    Synergistic Effect of Ibuprofen and Hydromorphone for Postoperative Pain

    Not yet reported Samsung Medical Center 90 participants Est. completion 2014-07 1 site
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT02479581

    The Safety and Efficacy of the Enhanced Recovery After Surgery(ERAS)Applied on Cardiac Surgery With Cardiopulmonary Bypass

    Not yet reported Xiangya Hospital of Central South University 226 participants Est. completion 2017-05 1 site Stand-alone
    Other conditions: Valvular Heart Disease
    View official trial listing →
  • Completed NCT NCT02483221

    Postoperative Pain Therapy With Hydromorphone TCI-PCA vs. Morphine PCA

    Not yet reported University of Erlangen-Nürnberg Medical School 50 participants Est. completion 2016-12-01 1 site
    Other conditions: Acute Postoperative Pain
    View official trial listing →
  • Completed NCT NCT02491385

    Thoracic Epidural for Postoperative Ileus

    Not yet reported Samsung Medical Center 28 participants Est. completion 2015-03 1 site Stand-alone
    Other conditions: Ileus
    View official trial listing →
  • Completed NCT NCT02501863

    Analgesic Effect of Ropivacaine Plus Fentanyl vs Ropivacaine for Continuous 3-in-1 FNB After Total Knee Arthroplasty

    Not yet reported National Medical Center, Seoul 40 participants Est. completion 2016-08 Stand-alone
    Other conditions: Pain
    View official trial listing →
  • Completed NCT NCT02509312

    Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery

    Not yet reported University Hospitals Cleveland Medical Center 70 participants Est. completion 2017-10 1 site
    Other conditions: Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity, Coagulation Defect; Postpartum, Postoperative Pain, Ketorolac Adverse Reaction, Blood Loss, Postoperative
    View official trial listing →
  • Status unknown NCT NCT02572804

    Comparing Rectus Sheath Catheter to Epidural Post Cystectomy

    Not yet reported Vancouver Coastal Health 160 participants Est. completion 2017-06 1 site
    Other conditions: Bladder Cancer, Postoperative Pain
    View official trial listing →
  • Completed NCT NCT02601027

    Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA

    Not yet reported Stanford University 120 participants Est. completion 2021-06 1 site Stand-alone
    Other conditions: Breast - Female
    View official trial listing →
  • Terminated NCT NCT02604589

    Continuous Intercostal Nerve Blockade for Traumatic Rib Fractures

    Not yet reported Anthony Iacco 10 participants Est. completion 2016-11 1 site Stand-alone
    Other conditions: Rib Fractures
    View official trial listing →
  • Completed NCT NCT02611752

    A Multiple Dose Opioid Challenge Study

    Not yet reported Braeburn Pharmaceuticals 47 participants Est. completion 2016-04 3 sites Stand-alone
    Substance use disorder
    View official trial listing →
  • Completed NCT NCT02621619

    IV Acetaminophen as an Analgesic Adjunct

    Not yet reported Montefiore Medical Center 159 participants Est. completion 2017-10 1 site Stand-alone
    Other conditions: Acute Pain
    View official trial listing →
  • Completed NCT NCT02625181

    Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

    Not yet reported Vanderbilt University 27034 participants Est. completion 2017-11-30 1 site Stand-alone
    Other conditions: Postoperative Nausea and Vomiting
    View official trial listing →
  • Status unknown NCT NCT02707874

    PIB Versus CI Through a Popliteal Sciatic Nerve Catheter for Analgesia Following Major Ankle Surgery

    Not yet reported University Health Network, Toronto 60 participants Est. completion 2018-06 1 site
    Other conditions: Pain, Postoperative
    View official trial listing →
  • Status unknown NCT NCT02727712

    Studies of Application of Combined General Anesthesia and Bilateral TPVB in OPCABG

    Not yet reported Xiangya Hospital of Central South University 60 participants Est. completion 2016-12 1 site Stand-alone
    Other conditions: Coronary Heart Disease
    View official trial listing →
  • Withdrawn NCT NCT02785003

    Ketamine in Colorectal Surgery

    Not yet reported Medical College of Wisconsin Est. completion 2018-08 1 site
    Other conditions: Acute Pain, Pain, Postoperative, Colorectal Surgery
    View official trial listing →
  • Completed NCT NCT02785055

    Neuraxial Ultrasound for Thoracic Epidural Placement

    Not yet reported Benaroya Research Institute 70 participants Est. completion 2014-02 1 site
    Other conditions: Analgesia, Epidural
    View official trial listing →
  • Terminated NCT NCT02787928

    Dose and Response of Intrathecal Hydromorphone in Patients Undergoing Cesarean Section at Virginia Commonwealth University Health System

    Not yet reported Virginia Commonwealth University 14 participants Est. completion 2017-12-31 1 site Stand-alone
    Other conditions: Cesarean Section, Obstetric Anesthesia
    View official trial listing →
  • Completed NCT NCT02789410

    Spinal Morphine vs. Hydromorphone for Pain Control After Cesarean Delivery

    Not yet reported Mayo Clinic 134 participants Est. completion 2018-03-15 1 site
    Other conditions: Analgesia, Obstetrical, Obstetric Surgical Procedures
    View official trial listing →
  • Status unknown NCT NCT02789969

    Pain Medications in Children Undergoing Strabismus Surgery

    Not yet reported St. Louis Children's Hospital 128 participants Est. completion 2017-04 1 site Stand-alone
    Other conditions: Pain, Nausea
    View official trial listing →
  • Completed NCT NCT02804633

    Decrease Opioid Consumption With Intra-Venous (IV) Acetaminophen After Colorectal Surgery (DOCIVA)

    Not yet reported Jewish Hospital, Cincinnati, Ohio 105 participants Est. completion 2015-03
    Other conditions: Pain Control Post Colorectal Surgery
    View official trial listing →
  • Status unknown NCT NCT02880800

    Does IVPCA Increase Opioid Consumption and Side Effects in Fast Track Orthopedic Procedures?

    Not yet reported Mount Sinai Hospital, Canada 80 participants Est. completion 2017-08 1 site Stand-alone
    Other conditions: Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT02886286

    Patient Controlled Intrathecal Analgesia With Bupivacaine for Chronic Low Back Pain

    Not yet reported University Hospitals Cleveland Medical Center 17 participants Est. completion 2017-12 1 site Stand-alone
    Other conditions: Pain, Intractable, Breakthrough Pain, Chronic Pain
    View official trial listing →
  • Completed NCT NCT02901275

    Enhancing Medication-based Analgesia in Humans

    Not yet reported Johns Hopkins University 29 participants Est. completion 2020-03-23 1 site Stand-alone
    Other conditions: Pain, Cannabis, Opioid Use, Unspecified
    View official trial listing →
  • Status unknown NCT NCT02909322

    Epidural Versus Paravertebral Block Analgesia After Hepatectomy

    Not yet reported Dr. Anthony Ho 50 participants Est. completion 2023-03 1 site Stand-alone
    Other conditions: Pain Control After Elective Hepatectomy
    View official trial listing →
  • Status unknown NCT NCT02920762

    Evaluation of Changes in Prescribing Behavior of ER/LA Opioid Prescribers

    ER/LA Opioid REMS Program Companies (RPC) 5575834 participants
    Other conditions: Opioid Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
    View official trial listing →
  • Terminated NCT NCT02929589

    Ibuprofen to Decrease Opioid Use and Post-operative Pain Following Unilateral Inguinal Herniorrhaphy

    Not yet reported Mike O'Callaghan Military Hospital 18 participants Est. completion 2021-08-23 1 site Stand-alone
    Other conditions: Pain, Hernia
    View official trial listing →
  • Completed NCT NCT02939209

    Pre-emptive Opioid Treatment to Prevent Rebound Pain After Arthroscopic Rotator Cuff Repair and/or Acromioplasty Under General Anesthesia and Interscalene Block

    Not yet reported Vishal Uppal 73 participants Est. completion 2022-05-31 2 sites Stand-alone
    Other conditions: Rotator Cuff Injury, Pain
    View official trial listing →
  • Status unknown NCT NCT02958566

    Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery

    Not yet reported University of Illinois College of Medicine at Peoria 80 participants Est. completion 2018-12 1 site
    Other conditions: Colon Cancer, Colon Diverticulosis, Colonic Neoplasms, Colonic Diverticulitis, Pain, Postoperative, Ileus, Ileus Paralytic, Ileus; Mechanical, Constipation Drug Induced, Constipation, Rectum Cancer, Rectum Neoplasm
    View official trial listing →
  • Terminated NCT NCT02987920

    Dextromethorphan Use in Multimodal Analgesia Regimens for Total Knee Arthroplasty

    Not yet reported University of Southern California 23 participants Est. completion 2018-01 Stand-alone
    Other conditions: Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT03001843

    Ketamine vs Hydromorphone

    Not yet reported University of Florida 54 participants Est. completion 2018-12-21 1 site
    Other conditions: Laparoscopic Gastric Bypass, Obesity, Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT03020875

    IV vs Oral Acetaminophen in Spine Fusion Perioperative Care

    Not yet reported Hospital for Special Surgery, New York 166 participants Est. completion 2025-02-03 1 site
    Other conditions: Multimodal Analgesic Approach
    View official trial listing →
  • Withdrawn NCT NCT03021083

    IONSYS Feasibility Study

    Not yet reported Hospital for Special Surgery, New York Est. completion 2017-11-01 Stand-alone
    Other conditions: Spinal Injury
    View official trial listing →
  • Completed NCT NCT03052816

    Ice T Postoperative Multimodal Pain Regimen in FPMRS Surgery

    Not yet reported University Hospitals Cleveland Medical Center 66 participants Est. completion 2018-06-30 1 site
    Other conditions: Pain, Postoperative, Pelvic Organ Prolapse
    View official trial listing →
  • Completed NCT NCT03088306

    Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients

    Not yet reported Johns Hopkins University 49 participants Est. completion 2018-08-31 1 site
    Other conditions: Lumbar Spinal Stenosis, Lumbar Spinal Instability, Lumbar Spine Degeneration
    View official trial listing →
  • Terminated NCT NCT03104816

    The Effectiveness of IV/PO Acetaminophen in the Perioperative Period in Reducing Opiate Use After Lumbar Spine Fusion

    Not yet reported University of Southern California 28 participants Est. completion 2017-12 1 site Stand-alone
    Other conditions: Fusion of Spine, Lumbar Region
    View official trial listing →
  • Completed NCT NCT03107481

    Acetaminophen IV vs Hydromorphone IV in the ED

    Not yet reported Montefiore Medical Center 220 participants Est. completion 2017-11-14 1 site
    Other conditions: Pain, Acute
    View official trial listing →
  • Terminated NCT NCT03115151

    Epidural and Intravenous Patient-Controlled Analgesia Following Lumbar Spinal Fusion Surgery

    Not yet reported University of Texas Southwestern Medical Center 46 participants Est. completion 2023-04-04 2 sites
    Other conditions: Pain
    View official trial listing →
  • Status unknown NCT NCT03128346

    Analgesic Effects of Transversus Thoracic Plane (TTP) Block in Cardiac Surgery

    Not yet reported Western University, Canada 100 participants Est. completion 2018-05-01 1 site Stand-alone
    Other conditions: Postoperative Pain, Nerve Block, Cardiac Surgery
    View official trial listing →
  • Completed NCT NCT03133845

    Shaping Anesthetic Techniques to Reduce Post-operative Delirium

    Not yet reported Johns Hopkins University 218 participants Est. completion 2020-05-25 1 site
    Osteoarthritis Other conditions: Delirium, Lumbar Radiculopathy, Lumbar Spine Disc Degeneration
    View official trial listing →
  • Completed NCT NCT03151434

    Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.

    Not yet reported Indiana University 147 participants Est. completion 2018-07-30 1 site
    Other conditions: Video Assisted Thoracoscopic Surgery, Pain, Postoperative, Pain, Acute
    View official trial listing →
  • Active, not recruiting NCT NCT03214510

    Thoracic Epidural Analgesia or Four-Quadrant Transversus Abdominus Plane Block in Reducing Pain in Patients Undergoing Liver Surgery

    Not yet reported M.D. Anderson Cancer Center 101 participants Est. completion 2027-07-31 1 site Stand-alone
    Other conditions: Liver and Intrahepatic Bile Duct Disorder
    View official trial listing →
  • Withdrawn NCT NCT03282669

    TC02 Obese Women Using It Morphine vs PCA IV Hydromorphone for Post-Cesarean Analgesia

    Not yet reported Northwestern University Est. completion 2021-12
    Other conditions: Pain, Postoperative, Obesity, Respiratory Insufficiency
    View official trial listing →
  • Completed NCT NCT03300674

    Intravenous Lidocaine Randomized Comparative Effectiveness Trial

    Not yet reported Montefiore Medical Center 154 participants Est. completion 2018-08-28 1 site
    Other conditions: Abdominal Pain
    View official trial listing →
  • Completed NCT NCT03309163

    Effect of Tramadol in Prevention of Postpartum Depression

    Not yet reported Xinqiao Hospital of Chongqing 1230 participants Est. completion 2019-08-13 1 site
    Other conditions: Caesarean Section
    View official trial listing →
  • Completed NCT NCT03313115

    Sleep/Wake Protocol Implementation to Improve Sleep Quality in the ICU

    University of Utah 685 participants Est. completion 2018-03-14 1 site
    Other conditions: Sleep Deprivation, Delirium
    View official trial listing →
  • Terminated NCT NCT03330119

    Determining the Effect of an "Alternate Recovery Protocol" Versus Current Standard of Care After Cesarean Section

    Not yet reported Brest, Norman A., M.D. 1494 participants Est. completion 2018-06-20 1 site
    Other conditions: Pregnancy Related, Narcotic Use
    View official trial listing →
  • Completed NCT NCT03375515

    PCA vs Non-PCA Intravenous Hydromorphone Titration for Severe Cancer Pain

    Not yet reported Fujian Cancer Hospital 214 participants Est. completion 2020-01-10 1 site Stand-alone
    Other conditions: Cancer Pain
    View official trial listing →
  • Completed NCT NCT03389750

    A Study to Evaluate the Abuse Potential of Oxymorphone Compared to Other Mu Opioid Agonists.

    Not yet reported New York State Psychiatric Institute 16 participants Est. completion 2023-06-28 2 sites
    Substance use disorder
    View official trial listing →
  • Withdrawn NCT NCT03393117

    Bupivacaine Versus Liposomal Bupivacaine For Breast Pain Management After Breast Recontruction

    Not yet reported Case Comprehensive Cancer Center Est. completion 2020-07-01 Stand-alone
    Other conditions: Breast Cancer
    View official trial listing →
  • Completed NCT NCT03411109

    Outcomes of Intrathecal Analgesia in Colorectal Surgery

    Mayo Clinic 601 participants Est. completion 2013-12-31 2 sites
    Other conditions: Surgery
    View official trial listing →
  • Completed NCT NCT03448068

    Perioperative Ketamine for Pain With Gastric Bypass

    Not yet reported Mayo Clinic 34 participants Est. completion 2020-01-09 1 site
    Other conditions: Laparoscopic Gastric Bypass Surgery, Ketamine
    View official trial listing →
  • Terminated NCT NCT03450096

    Continous Lumbar Plexus Block in Children

    Not yet reported Insel Gruppe AG, University Hospital Bern 33 participants Est. completion 2022-05-16 1 site
    Other conditions: Regional Anesthesia, Pediatric Anesthesia, Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT03458598

    Pre-Operative Single Shot Rectus Sheath Block

    Not yet reported University of Alberta 49 participants Est. completion 2019-02-05 1 site
    Other conditions: Bladder Neoplasm, Prostate Neoplasm, Pelvic Neoplasm, Urologic Neoplasms, Opioid Use, Anesthesia, Local, Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT03471442

    Erector Spinae Plane Block Versus Paravertebral Block

    Not yet reported University of Alberta 48 participants Est. completion 2021-04-27 1 site Stand-alone
    Other conditions: Breast Cancer, Pain, Postoperative, Anesthesia, Local
    View official trial listing →
  • Completed NCT NCT03472469

    MAST Trial: Multi-modal Analgesic Strategies in Trauma

    Not yet reported The University of Texas Health Science Center, Houston 1561 participants Est. completion 2019-07-03 1 site
    Other conditions: Nonspecific Pain Post Traumatic Injury
    View official trial listing →
  • Terminated NCT NCT03478423

    Opioid Analgesics for Acute Fracture Pain in Adults Discharged From the ED

    Not yet reported Mount Sinai Hospital, Canada 5 participants Est. completion 2019-09-17 1 site Stand-alone
    Other conditions: Acute Pain
    View official trial listing →
  • Withdrawn NCT NCT03502421

    Ketamine Sickle Cell Disease

    Not yet reported University of South Florida Est. completion 2019-11-01
    Other conditions: SC Disease, Pain, Chronic
    View official trial listing →
  • Completed NCT NCT03521102

    Acetaminophen Versus IV Hydromorphone for Pain in the Elderly in the ED

    Not yet reported Montefiore Medical Center 162 participants Est. completion 2022-03-23 1 site
    Other conditions: Acute Pain
    View official trial listing →
  • Completed NCT NCT03534063

    Implementing Genomics in Practice (IGNITE): CYP2D6 Genotype-Guided Pain Management in Patients Undergoing Arthroplasty Surgery

    Not yet reported University of Florida 260 participants Est. completion 2020-04-29 3 sites
    Other conditions: Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT03541759

    Pain Management After Elective Shoulder Surgery

    Not yet reported AUVA Traumazentrum Vienna Site UKH Meidling 48 participants Est. completion 2018-05-17 1 site
    Other conditions: Postoperative Pain
    View official trial listing →
  • Completed NCT NCT03553498

    IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients

    Not yet reported Albert Einstein College of Medicine 162 participants Est. completion 2019-05-15 1 site Stand-alone
    Other conditions: Acute Pain
    View official trial listing →
  • Status unknown NCT NCT03564548

    Inhaled Cannabinoids Versus Immediate-release Oral Opioids for the Management of Breakthrough Cancer Pain

    Not yet reported Tetra Bio-Pharma 20 participants Est. completion 2022-04 1 site
    Other conditions: Cancer, Breakthrough Cancer Pain
    View official trial listing →
  • Terminated NCT NCT03579446

    Levorphanol as a Second Line Opioid in Reducing Pain in Patients With Cancer

    Not yet reported M.D. Anderson Cancer Center 43 participants Est. completion 2023-06-15 1 site Stand-alone
    Other conditions: Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm
    View official trial listing →
  • Completed NCT NCT03592992

    Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia

    Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 126 participants Est. completion 2022-07-28 1 site Stand-alone
    Other conditions: Postoperative Pain
    View official trial listing →
  • Status unknown NCT NCT03619785

    US-guided SAPB for Rib Fractures in the ED

    Not yet reported Andrew A Herring 70 participants Est. completion 2019-08-31 1 site
    Other conditions: Rib Fractures, Rib Fracture Multiple
    View official trial listing →
  • Completed NCT NCT03648008

    Postoperative Analgesic Effect of Hydromorphone on Partial Pulmonary Resection Under Video-assisted Thoracoscopy

    Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 171 participants Est. completion 2018-09-01 1 site Stand-alone
    Other conditions: Pain, Postoperative, Thoracic Surgery, Video-Assisted
    View official trial listing →
  • Completed NCT NCT03726268

    Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement)

    Not yet reported Duke University 907 participants Est. completion 2024-01-30 1 site
    Other conditions: Opioid Use, Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT03743194

    Pectoralis and Serratus Muscle Blocks

    Not yet reported The Cleveland Clinic 210 participants Est. completion 2022-03-14 1 site
    Other conditions: Post Operative Pain Control
    View official trial listing →
  • Completed NCT NCT03757559

    A Trial to Evaluate the Abuse Potential of 3 Doses of GRT6005 in Adult Non-dependent Recreational Opioid Users

    Not yet reported Tris Pharma, Inc. 226 participants Est. completion 2014-03-08 1 site Stand-alone
    Other conditions: Abuse, Drug
    View official trial listing →
  • Completed NCT NCT03760809

    Dexmedetomidine Combined With Hydromorphone in Tonsillectomy and Adenoidectomy

    Not yet reported Eye & ENT Hospital of Fudan University 130 participants Est. completion 2019-04-01 1 site
    Other conditions: Agitated; State, Acute Reaction to Stress
    View official trial listing →
  • Status unknown NCT NCT03766269

    Dronabinol Opioid Sparing Evaluation (DOSE) Trial

    Not yet reported Daisy Pharma Opioid Venture, LLC 280 participants Est. completion 2019-07-01 1 site
    Other conditions: Chronic Pain
    View official trial listing →
  • Completed NCT NCT03767933

    Non-Steroidal or Opioid Analgesia Use for Children With Musculoskeletal Injuries

    Not yet reported University of Alberta 710 participants Est. completion 2023-03-22 6 sites Stand-alone
    Other conditions: Musculoskeletal Injury
    View official trial listing →
  • Completed NCT NCT03768024

    A Clinical Study in Healthy Adults Who Sometimes Take Drugs for Pleasure Which Aims to Evaluate Whether GRT0151Y is Likely to be Abused

    Not yet reported Grünenthal GmbH 76 participants Est. completion 2007-10-25 1 site Stand-alone
    Other conditions: Pain, Acute Pain
    View official trial listing →
  • Completed NCT NCT03789318

    Study in Subjects Undergoing Complete Abdominoplasty

    Not yet reported Concentric Analgesics 54 participants Est. completion 2019-06-12 1 site
    Other conditions: Postsurgical Pain
    View official trial listing →
  • Completed NCT NCT03860480

    Erector Spinae Plane Block For Analgesia Following Video-Assisted Thoracoscopic Surgery

    Not yet reported Ciusss de L'Est de l'Île de Montréal 52 participants Est. completion 2021-12-16 1 site
    Other conditions: Thoracic Surgery, Video-Assisted
    View official trial listing →
  • Terminated NCT NCT03933397

    Comparing Individualized vs. Weight Based Protocols to Treat Vaso-Occlusive Episodes in Sickle Cell Disease

    Not yet reported Duke University 328 participants Est. completion 2022-05-20 6 sites Stand-alone
    Other conditions: Sickle Cell Disease
    View official trial listing →
  • Terminated NCT NCT03933865

    Acute Pain Management in Patients on Opioid Replacement Therapy

    Not yet reported University of California, San Francisco 1 participants Est. completion 2022-02-24 1 site
    Other conditions: Opioid-use Disorder, Pain, Acute
    View official trial listing →
  • Completed NCT NCT03972397

    Intercostal Nerve Cryoablation for Postoperative Pain Management

    Not yet reported The University of Texas Health Science Center, Houston 20 participants Est. completion 2022-09-22 1 site Stand-alone
    Other conditions: Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT03987022

    ICE-T Pain Regimen for Total Laparoscopic Hysterectomy

    Not yet reported MetroHealth Medical Center 66 participants Est. completion 2022-04-25 1 site Stand-alone
    Other conditions: Opioid Substitution Treatment
    View official trial listing →
  • Terminated NCT NCT03990038

    Comparison of Two Multimodal Analgesia Regimens in Total Knee Arthroplasty

    Not yet reported Ciusss de L'Est de l'Île de Montréal 2 participants Est. completion 2019-10-01 1 site
    Other conditions: Postoperative Pain
    View official trial listing →
  • Completed NCT NCT04018664

    Oral Abuse Potential Study of Nalbuphine

    Not yet reported Trevi Therapeutics 56 participants Est. completion 2020-06-02 1 site Stand-alone
    Other conditions: Nalbuphine, Opioid Abuse
    View official trial listing →
  • Completed NCT NCT04033094

    Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB)

    Daiichi Sankyo 17566 participants Est. completion 2020-12-31 1 site
    Other conditions: Baseline Epidemiologic Assessment
    View official trial listing →
  • Completed NCT NCT04036968

    Enhancing Medication-based Analgesia in Humans- STUDY 2

    Not yet reported Johns Hopkins University 31 participants Est. completion 2022-11-01 1 site Stand-alone
    Other conditions: Pain, Cannabis, Opioid Use
    View official trial listing →
  • Completed NCT NCT04081376

    Generation of Biological Samples Positive to Hydromorphone for Anti-doping Control

    Not yet reported Parc de Salut Mar 2 participants Est. completion 2019-12-18 1 site Stand-alone
    Other conditions: Healthy Volunteers
    View official trial listing →
  • Completed NCT NCT04111328

    the Effect of Different Drugs and Infusion Ways on Degree of Postoperative Comfort

    Not yet reported Jun Wang 600 participants Est. completion 2020-10-30 1 site Stand-alone
    Other conditions: Analgesia, Patient-Controlled
    View official trial listing →
  • Withdrawn NCT NCT04132011

    Dosing Intervals of Opioid Medication for Chronic Pain

    Not yet reported University Health Network, Toronto Est. completion 2020-03-08 1 site
    Other conditions: Chronic Pain
    View official trial listing →
  • Completed NCT NCT04176783

    Opioid-Free Orthopaedic Surgery

    Not yet reported OrthoCarolina Research Institute, Inc. 511 participants Est. completion 2024-12-31 1 site
    Other conditions: Pain Management
    View official trial listing →
  • Completed NCT NCT04221165

    Opioid Therapy vs Multimodal Analgesia in Head and Neck Cancer

    Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 49 participants Est. completion 2023-09-15 1 site
    Other conditions: Head and Neck Cancer, Radiation-Induced Mucositis
    View official trial listing →
  • Completed NCT NCT04230681

    Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery

    Not yet reported Washington University School of Medicine 189 participants Est. completion 2022-04-01 1 site
    Obstructive sleep apnea Other conditions: Tonsillitis
    View official trial listing →
  • Status unknown NCT NCT04234191

    Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder

    Not yet reported University of British Columbia 50 participants Est. completion 2025-01 1 site Stand-alone
    Substance use disorder
    View official trial listing →
  • Completed NCT NCT04240626

    Multimodal Analgesia Effect on Post Surgical Patient

    Not yet reported University of California, Davis 60 participants Est. completion 2025-06-24 1 site Stand-alone
    Other conditions: Obesity, Morbid, Surgery, Bariatric Surgery Candidate
    View official trial listing →
  • Completed NCT NCT04243954

    Intravenous vs Oral Analgesia in Cancer Patients With Severe Pain After Successful Titration

    Not yet reported Fujian Cancer Hospital 95 participants Est. completion 2020-11-21 1 site Stand-alone
    Other conditions: Cancer Pain
    View official trial listing →
  • Completed NCT NCT04258631

    Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies

    Not yet reported Mayo Clinic 105 participants Est. completion 2023-08-08 1 site Stand-alone
    Other conditions: Malignant Female Reproductive System Neoplasm
    View official trial listing →
  • Withdrawn NCT NCT04280939

    Spinal Anesthetic for Hip and Knee Replacement Surgery - Intrathecal Morphine or Hydromorphone

    Not yet reported Hopital Montfort Est. completion 2021-03-31 Stand-alone
    Other conditions: Spinal Anesthesia
    View official trial listing →
  • Status unknown NCT NCT04286152

    Mirabegron And Ureteral Stent-related Pain (MAP) Trial

    Not yet reported Unity Health Toronto 142 participants Est. completion 2021-06-30 1 site Stand-alone
    Other conditions: Nephrolithiasis
    View official trial listing →
  • Terminated NCT NCT04291599

    Initial Pain Management in Pediatric Pancreatitis: Opioid vs. Non-Opioid

    Not yet reported Boston Children's Hospital 23 participants Est. completion 2025-07-24 1 site
    Other conditions: Acute Pancreatitis
    View official trial listing →
  • Active, not recruiting NCT NCT04296305

    Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain

    Not yet reported M.D. Anderson Cancer Center 84 participants Est. completion 2027-12-31 1 site Stand-alone
    Other conditions: Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
    View official trial listing →
  • Completed NCT NCT04300231

    Thoracic Epidural Analgesia Versus Rectus Sheath Block Versus Surgeon Infiltration With Liposomal Bupivacaine or Standard Bupivacaine for Post-Operative Pain Control After Cystectomy

    Not yet reported Indiana University 160 participants Est. completion 2021-12-24 1 site
    Other conditions: Cystectomy
    View official trial listing →
  • Completed NCT NCT04311827

    Serratus Anterior Plane Block for Improving Pain and Respiratory Function in Patients With Multiple Rib Fractures

    Stanford University 39 participants Est. completion 2021-12-31 1 site
    Other conditions: Rib Fracture Multiple
    View official trial listing →
  • Completed NCT NCT04396587

    Non-analgesic Effects Produced by Equipotent Analgesic Doses of Sufentanil, Hydromorphone, and Oxycodone

    Not yet reported Peking University People's Hospital 80 participants Est. completion 2023-06-01 1 site Stand-alone
    Other conditions: Opioid Use
    View official trial listing →
  • Terminated NCT NCT04398316

    High Dose IV Lidocaine vs Hydromorphone for Abdominal Pain in the Emergency Department

    Not yet reported Hennepin Healthcare Research Institute 4 participants Est. completion 2021-06-30 1 site
    Other conditions: Abdominal Pain, Renal Colic
    View official trial listing →
  • Withdrawn NCT NCT04421196

    Opioid-free Total Hip Arthroplasty

    Not yet reported Johns Hopkins University Est. completion 2023-12-01
    Osteoarthritis
    View official trial listing →
  • Completed NCT NCT04429022

    Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy

    Not yet reported State University of New York at Buffalo 68 participants Est. completion 2022-05-31 1 site Stand-alone
    Other conditions: Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT04436224

    Hydromorphone for ICU-analgesia in Patients With Non-mechanical Ventilation

    Not yet reported Nanfang Hospital, Southern Medical University 530 participants Est. completion 2025-05-30 1 site Stand-alone
    Other conditions: Hydromorphone, Analgesia, ICU
    View official trial listing →
  • Withdrawn NCT NCT04464512

    Suboxone User Perioperative Early Referral and Enhanced Recovery After Surgery- Orthopaedic Trauma Surgery Population

    Not yet reported West Virginia University Est. completion 2021-08-22 1 site
    Other conditions: Addiction Opiate, Chronic Pain, Fractures, Bone, Buprenorphine Dependence
    View official trial listing →
  • Status unknown NCT NCT04538573

    Virtual Reality MObility for Burn Patients

    Not yet reported St. Justine's Hospital 20 participants Est. completion 2024-05-30 1 site
    Other conditions: Pediatric Burns
    View official trial listing →
  • Completed NCT NCT04566250

    Non-Opioid Prescriptions After Arthroscopic Surgery in Canada (NO PAin)

    Not yet reported McMaster University 200 participants Est. completion 2022-04-01 3 sites
    Other conditions: Knee Arthroscopy, Shoulder Arthroscopy
    View official trial listing →
  • Completed NCT NCT04606264

    Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data

    Not yet reported Jennifer Holder-Murray 3395 participants Est. completion 2025-03-21 3 sites
    Other conditions: Perioperative Optimization
    View official trial listing →
  • Status unknown NCT NCT04613869

    The Effect of Esketamine on Patients Undergoing Tumor Surgery

    Not yet reported Second Affiliated Hospital, Zhejiang University, School of Medicine 282 participants Est. completion 2021-10-15 1 site Stand-alone
    Other conditions: Tumor Surgery
    View official trial listing →
  • Status unknown NCT NCT04614610

    Lidocaine Intravenous in the Emergency Department For Sickle Cell Crisis

    Not yet reported Community Medical Center, Toms River, NJ 100 participants Est. completion 2025-06-01 3 sites
    Other conditions: Sickle Cell Disease, Sickle Cell Crisis, Pain, Acute
    View official trial listing →
  • Withdrawn NCT NCT04639011

    Duloxetine Tibial Plateau

    Not yet reported Boston Medical Center Est. completion 2023-12 2 sites Stand-alone
    Other conditions: Tibial Plateau Fracture, Pain, Postoperative
    View official trial listing →
  • Terminated NCT NCT04716413

    Evaluating the Use of Sublingual Sufentanil in Patients With Suboxone Treatment

    Not yet reported Montefiore Medical Center 3 participants Est. completion 2022-11-18 1 site Stand-alone
    Other conditions: Acute Pain
    View official trial listing →
  • Completed NCT NCT04752033

    Intrathecal Opioids for Colorectal Resection

    Not yet reported Mayo Clinic 80 participants Est. completion 2023-02-17 1 site Stand-alone
    Other conditions: Colorectal Surgery, Pain, Postoperative, Analgesic, Opioid
    View official trial listing →
  • Completed NCT NCT04785768

    IV PCA With or Without Continuous Dose vs Oral Opioid to Maintain Analgesia for Severe Cancer Pain After Successful Titration

    Not yet reported Fujian Cancer Hospital 1372 participants Est. completion 2024-07-01 1 site Stand-alone
    Other conditions: Cancer Pain
    View official trial listing →
  • Completed NCT NCT04837014

    Eliminating Narcotic Prescriptions from Outpatient Minimally Invasive Gynecologic Surgery

    Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 110 participants Est. completion 2024-10-21 1 site
    Other conditions: Pain, Postoperative, Opioid Use
    View official trial listing →
  • Completed NCT NCT04973748

    Conditioned Open-label Placebo (COLP) for Peri-operative Pain Management in Patients With Head and Neck Cancer

    Not yet reported Johns Hopkins University 9 participants Est. completion 2024-06-28 1 site Stand-alone
    Other conditions: Postoperative Pain, Opioid Use
    View official trial listing →
  • Terminated NCT NCT05017246

    Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy

    Not yet reported Washington University School of Medicine 110 participants Est. completion 2024-08-29 1 site Stand-alone
    Other conditions: Cancer Debulking, Enlarged Uterus, Fibroid Uterus, Adnexal Mass
    View official trial listing →
  • Status unknown NCT NCT05063396

    OFA in Thoracic Surgery

    Not yet reported Shanghai Zhongshan Hospital 60 participants Est. completion 2025-12-01 2 sites
    Other conditions: Thoracic Cancer
    View official trial listing →
  • Completed NCT NCT05099055

    Dexmedetomine as Adjuvant for Spinal Anesthesia in Elective Cesarian Sections : a Pilot Study

    Not yet reported St. Justine's Hospital 42 participants Est. completion 2023-05-05 1 site Stand-alone
    Other conditions: Analgesia, Analgesics, Opioid, Anesthesia, Obstetrical, Anesthesia, Spinal, Analgesics, Non-Narcotic, Dexmedetomidine, Analgesia, Obstetrical
    View official trial listing →
  • Status unknown NCT NCT05200806

    A Prospective Pilot Study of a Non-Narcotic Post-Operative Course After Colectomy

    Not yet reported University of Vermont 25 participants Est. completion 2024-10 1 site
    Other conditions: Analgesia, Post-Operative Pain, Breakthrough Pain, Colectomy
    View official trial listing →
  • Enrolling by invitation NCT NCT05231460

    Pain Management Study

    Not yet reported University of Arizona 244 participants Est. completion 2026-06 1 site
    Other conditions: Pain, Postoperative
    View official trial listing →
  • Completed NCT NCT05244226

    Pediatric Pain Optimization After Tonsillectomy

    Not yet reported Duke University 66 participants Est. completion 2023-05-10 1 site
    Obstructive sleep apnea Other conditions: Tonsillitis, Pain, Procedural
    View official trial listing →
  • Completed NCT NCT05252858

    A Pilot Study Investigating the nCAP Signal Relief Patch in Subjects Undergoing Primary Hip or Knee Replacement Surgery

    Not yet reported Jacques E. Chelly 79 participants Est. completion 2022-10-08 1 site Stand-alone
    Other conditions: Opioid Use, Pain, Post Operative
    View official trial listing →
  • Completed NCT NCT05279898

    Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies

    Not yet reported Beth Israel Deaconess Medical Center 70 participants Est. completion 2024-12-31 1 site Stand-alone
    Other conditions: Postoperative Delirium, Hemodynamic Instability, Pain, Neurocognitive Dysfunction
    View official trial listing →
  • Withdrawn NCT NCT05325164

    Methadone for 'Adenocarcinopathic' Pain Treatment

    Not yet reported Ottawa Hospital Research Institute Est. completion 2023-09
    Other conditions: Cancer Pain, Adenocarcinoma
    View official trial listing →
  • Completed NCT NCT05375916

    Comparison of Short-term Sustained-release Opioid in Open Abdominal Urologic Surgeries

    Not yet reported University of Alberta 80 participants Est. completion 2023-11-30 1 site Stand-alone
    Other conditions: Pain, Acute, Opioid Use
    View official trial listing →
  • Completed NCT NCT05414006

    Effect of S-ketamine in Cesarean Section Combined Anesthesia

    Not yet reported The Second Affiliated Hospital of Chongqing Medical University 120 participants Est. completion 2022-09-05 1 site Stand-alone
    Other conditions: Postoperative Pain
    View official trial listing →
  • Terminated NCT NCT05552443

    A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis Repair

    Not yet reported Mayo Clinic 31 participants Est. completion 2024-12-31 1 site Stand-alone
    Other conditions: Pain Control
    View official trial listing →
  • Status unknown NCT NCT05565495

    The Effects of ECMO on the Pharmacokinetics of Hydromorphone

    Not yet reported Xiaobo Yang, MD 26 participants Est. completion 2024-09-01 1 site Stand-alone
    Other conditions: Extracorporeal Membrane Oxygenation
    View official trial listing →
  • Status unknown NCT NCT05571176

    KetaMoHydBup: Pharmacokinetic Interaction of S-ketamine, Morphine, Hydromorphone and Buprenorphine

    Not yet reported Elina Brinck 12 participants Est. completion 2023-12
    Other conditions: The Effect of S-ketamine on Pharmacokinetics of Morphine, Hydromorphone, and Buprenorphine
    View official trial listing →
  • Completed NCT NCT05576675

    Patient-controlled Intravenous Analgesia Combined With Different Opioid Receptors for Gastrointestinal Surgery

    Not yet reported Xijing Hospital 4342 participants Est. completion 2022-03-31 1 site Stand-alone
    Other conditions: Gastrointestinal Surgery
    View official trial listing →
  • Completed NCT NCT05579223

    Intrathecal Hydromorphone for Postoperative Pain of Anorectal Surgery

    Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 150 participants Est. completion 2024-01-27 1 site Stand-alone
    Other conditions: Acute Pain, Post Operative Pain, Anorectal Disorder, Analgesia
    View official trial listing →
  • Completed NCT NCT05610072

    Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine)

    Not yet reported William Stoops 12 participants Est. completion 2026-03-27 2 sites Stand-alone
    Substance use disorder Other conditions: Cocaine Use Disorder, Stimulant Use Disorder
    View official trial listing →
  • Withdrawn NCT NCT05693675

    Postoperative Oral Methadone After Major Spine Surgery; Safety, Feasibility and Efficacy in Prevention of Progression to Chronic Opioid Usage at 3 Months

    Not yet reported, Not yet reported The University of Texas Health Science Center, Houston Est. completion 2024-07-01 1 site Stand-alone
    Other conditions: Spine Surgery
    View official trial listing →
  • Active, not recruiting NCT NCT05708521

    Personalization of Opioid Prescription Following Orthognathic Surgery

    Not yet reported Nova Scotia Health Authority 201 participants Est. completion 2026-05-01 1 site Stand-alone
    Substance use disorder Other conditions: Pain, Postoperative, Orthognathic Surgery, Opioid Use, Patient Satisfaction
    View official trial listing →
  • Completed NCT NCT05740657

    Observational Study on the Incorporation of Opioids and Their Metabolites Into Hair of Pediatric Patients

    University of Zurich 150 participants Est. completion 2025-02-28 1 site
    Other conditions: Opioid Use, Unspecified
    View official trial listing →
  • Status unknown NCT NCT05744089

    Home Management of Simple Hydromorphone PCA Pump Mode

    Not yet reported The First Affiliated Hospital of Xinxiang Medical College 50 participants Est. completion 2025-02 1 site Stand-alone
    Other conditions: Cancer Pain, Tumor, Solid, Carcinoma
    View official trial listing →
  • Completed NCT NCT05769842

    Effects of Propofol on Respiratory Adverse Events During Extubation in Children Undergoing Tonsil Adenoidectomy

    Not yet reported Children's Hospital of Fudan University 239 participants Est. completion 2024-01-01 1 site Stand-alone
    Other conditions: Airway Complication of Anesthesia
    View official trial listing →
  • Status unknown NCT NCT05848635

    Hydromorphone for Perioperative Analgesia in Lung Tumor Ablation Parallel Controlled

    Not yet reported Qianfoshan Hospital 88 participants Est. completion 2024-05-01 Stand-alone
    Other conditions: Pulmonary Nodule, Ablation
    View official trial listing →
  • Completed NCT NCT05901441

    Effect of Epidural Hydromorphone Combined With Ropivacaine in Labor Analgesia

    Not yet reported Maternal and Child Health Hospital of Hubei Province 240 participants Est. completion 2023-05-30 1 site Stand-alone
    Other conditions: Analgesia, Labor Pain
    View official trial listing →
  • Completed NCT NCT06015555

    TAMO Therapy Versus Postural Control Exercise in Children With Congenital Muscular Torticollis

    Not yet reported khadija liaquat 18 participants Est. completion 2023-07-01 1 site
    Other conditions: Torticollis Congenital
    View official trial listing →
  • Status unknown NCT NCT06036797

    Efficacy and Safety of Hydromorphone-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia

    Not yet reported Maternal and Child Health Hospital of Hubei Province 240 participants Est. completion 2023-10-17 1 site Stand-alone
    Other conditions: Analgesia, Labor Pain
    View official trial listing →
  • Terminated NCT NCT06110546

    Impact of Methadone on Prolonged Mechanical Ventilation in Patients on Continuous Treatment With Opioids

    Not yet reported The University of Texas Health Science Center, Houston 2 participants Est. completion 2024-02-22 1 site Stand-alone
    Other conditions: Effect of Methadone on the Duration on Mechanical Ventilation
    View official trial listing →
  • Completed NCT NCT06205199

    Analgesic Effect of Ropivacaine Combined With Hydromorphone for CSEA After Total Knee Arthroplasty

    Not yet reported Second Hospital of Jilin University 136 participants Est. completion 2023-11-30 1 site Stand-alone
    Other conditions: Postoperative Analgesia
    View official trial listing →
  • Completed NCT NCT06218160

    The Addition of Hydromorphone to Local Anesthetics for the Repair of Inguinal Hernias in Elderly Patients

    Not yet reported Second Hospital of Jilin University 63 participants Est. completion 2023-12-25 1 site Stand-alone
    Other conditions: Inguinal Hernia
    View official trial listing →
  • Withdrawn NCT NCT06240390

    Effectiveness of Percutaneous Neuromodulation vs Pharmacological Treatment in Cancer Patients With Anterior Knee Pain

    Not yet reported Universidad Europea de Canarias Est. completion 2025-02-01 1 site Stand-alone
    Other conditions: Pain Cancer
    View official trial listing →
  • Completed NCT NCT06274307

    Efficacy of Transversus Abdominis Plane Block

    Not yet reported Justin Hruska 106 participants Est. completion 2025-03-01 2 sites
    Other conditions: Anesthesia, Local
    View official trial listing →
  • Terminated NCT NCT06406400

    Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

    Not yet reported AstraZeneca 15 participants Est. completion 2024-07-31 1 site Stand-alone
    Substance use disorder
    View official trial listing →
  • Suspended NCT NCT06429657

    Ketamine for Sedation in Severe Traumatic Brain Injury

    Not yet reported Henry M. Jackson Foundation for the Advancement of Military Medicine 50 participants Est. completion 2027-06-30 1 site
    Other conditions: Severe Traumatic Brain Injury, Intracranial Hypertension, Intracranial Hemorrhage, Hypertensive
    View official trial listing →
  • Completed NCT NCT06575699

    Rectus Sheath Block for Analgesia After Gynecological Laparotomy

    Not yet reported Duke University 90 participants Est. completion 2025-11-28 1 site
    Other conditions: Gynecologic Surgical Procedures
    View official trial listing →
  • Active, not recruiting NCT NCT06669650

    Personalized Post-Operative Pain Management

    Not yet reported University of Tennessee Graduate School of Medicine 208 participants Est. completion 2025-12 1 site Stand-alone
    Other conditions: Persistent Post Operative Opioid Use, Post-surgical Pain
    View official trial listing →
  • Enrolling by invitation NCT NCT06716359

    Comparison of the Effects of Hydromorphone and Nalbuphine Patient Controlled Analgesia in Postoperative Pain After Cesarean Section

    Huazhong University of Science and Technology 240 participants Est. completion 2025-05-31 1 site
    Other conditions: Postoperative Pain, Patiet Controlled Analgesia
    View official trial listing →
  • Withdrawn NCT NCT06784180

    Intrathecal Hydromorphone vs Intrathecal Morphine to Treat Post Cesarean Pain in Patients With Opioid Use Disorder Taking Buprenorphine

    Not yet reported University of North Carolina, Chapel Hill Est. completion 2029-01 1 site Stand-alone
    Substance use disorder
    View official trial listing →
  • Completed NCT NCT06823180

    Hydromorphone Hydrochloride Epidural Preemptive Analgesia for Postoperative Pain After Cesarean Section

    Not yet reported Liquan Liang 105 participants Est. completion 2025-08-28 1 site Stand-alone
    Other conditions: Post-surgical Pain
    View official trial listing →
  • Not yet recruiting NCT NCT06848452

    Clinical Study on the Efficacy and Safety of Hydromorphone for ICU Analgesia

    Affiliated Hospital of Nantong University 300 participants Est. completion 2027-12-31 1 site
    Other conditions: Analgesia, ICU Patients Requiring Invasive Mechanical Ventilation
    View official trial listing →
  • Completed NCT NCT06868589

    Reducing Pain With Methadone and Ketamine in Liver Transplant

    Not yet reported Lahey Clinic 50 participants Est. completion 2026-06-01 2 sites
    Other conditions: Liver Transplantation
    View official trial listing →
  • Suspended NCT NCT06940570

    Methadone as an Alternative Treatment for Children Underdoing HSCT

    Not yet reported University of Texas Southwestern Medical Center 60 participants Est. completion 2029-08-01 1 site
    Other conditions: Leukemia, Aplastic Anemia, Bone Marrow Failure Syndromes, SCID
    View official trial listing →
  • Completed NCT NCT06985069

    Outcome of Multimodal Anesthesia Bern

    Not yet reported Insel Gruppe AG, University Hospital Bern 240 participants Est. completion 2025-09-18 1 site
    Other conditions: Opioid Use, Pain, Postoperative, Postoperative Complications, Postoperative Nausea
    View official trial listing →
  • Completed NCT NCT07014644

    A Randomized, Double-Blind, Single-Center Clinical Study on the Efficacy of Naltrexone Implant in Antagonizing Opioid Agonist Hydromorphone

    Not yet reported Shenzhen Sciencare Medical Industries Co., Ltd. 31 participants Est. completion 2020-05-19 1 site
    Other conditions: Opioid Dependence
    View official trial listing →
  • Withdrawn NCT NCT07092475

    The Impact of Intraoperative Methadone on Postoperative Opioid Use

    Not yet reported University of Utah Est. completion 2025-11 1 site
    Other conditions: Breast Cancer, Opioid Use
    View official trial listing →
  • Not yet recruiting NCT NCT07175363

    Butorphanol for Pain Relief After Cesarean Section: A Retrospective Study

    Sichuan Provincial People's Hospital 2500 participants Est. completion 2026-06-30
    Other conditions: Caesarean Section
    View official trial listing →
  • Completed NCT NCT07224620

    Fentanyl Versus Hydromorphone in Patients on Mechanical Ventilation

    Not yet reported Beth Israel Deaconess Medical Center 319 participants Est. completion 2026-06-30 1 site Stand-alone
    Other conditions: Mechanical Ventilation, Sedation and Analgesia, Critical Care, Intensive Care
    View official trial listing →
  • Completed NCT NCT07315022

    Enhanced Recovery After Surgery-Based Multimodal Preemptive Analgesia for Perioperative Management in Transarterial Chemoembolization of Intermediate-to-Advanced Hepatocellular Carcinoma

    Not yet reported First Affiliated Hospital, Sun Yat-Sen University 129 participants Est. completion 2025-08-30 1 site Stand-alone
    Other conditions: Enhanced Recovery After Surgery, Multimodal Analgesia, Real-world Study, Transarterial Chemoembolization
    View official trial listing →
  • Not yet recruiting NCT NCT07421674

    Assessing Hydromorphone Sustained-Release Tablets in Elderly Cancer Pain Patients With Renal Insufficiency

    Taian Cancer Hospital 62 participants Est. completion 2028-12-31 1 site
    Other conditions: Cancer Pain, Renal Insufficiency Chronic, Hydromorphone Use
    View official trial listing →
  • Not yet recruiting NCT NCT07565870

    Methadone for Enhanced Postoperative Analgesia in Intermediate-Risk Noncardiac Surgery (MELODY)

    Not yet reported Alexandre P. Joosten 400 participants Est. completion 2027-03-30 1 site
    Other conditions: Postoperative Pain, Recovery
    View official trial listing →
  • Not yet recruiting NCT NCT07588802

    Effect of Opioid-Sparing Anesthesia on Postoperative Opioid Consumption and Pain in Elderly Patients Undergoing Spine Surgery

    Not yet reported Massachusetts General Hospital 120 participants Est. completion 2027-05
    Other conditions: Opoid Managment, Pain Management
    View official trial listing →
  • Not yet recruiting NCT NCT07697690

    Thoracic Epidural Analgesia for Acute Pancreatitis With Early Organ Dysfunction

    Not yet reported First People's Hospital of Chenzhou 150 participants Est. completion 2028-09-01
    Other conditions: Organ Dysfunction, Organ Support, Acute Pancreatitis (AP)
    View official trial listing →
  • Completed NCT NCT07722234

    Clinical Practice of Hydromorphone in Multimodal Analgesia for Enhanced Recovery After Surgery (ERAS) in Knee Arthroplasty

    Not yet reported China-Japan Friendship Hospital 90 participants Est. completion 2026-06-13 1 site Stand-alone
    Other conditions: VAS Score, Quadriceps Strength
    View official trial listing →
  • Completed NCT NCT07744503

    Comparing Local Anesthetic Injections to Nerve Blocks for Pain Control After Total Knee Replacement

    Not yet reported Christopher Male 78 participants Est. completion 2026-01-31 1 site Stand-alone
    Osteoarthritis Other conditions: Pain, Postoperative, Arthroplasty, Replacement, Knee
    View official trial listing →
  • Not yet recruiting NCT NCT07799571

    Buprenorphine for the Management of Pain in Children With Sickle Cell Disease

    Not yet reported Natasha Archer 25 participants Est. completion 2032-10 1 site Stand-alone
    Other conditions: Sickle Cell Disease (SCD), Sickle Cell Disease Vaso-occlusive Crisis, Sickle Cell Anemia Crisis, Sickle Cell Anemia in Children, Sickle Cell Anemia (HbSS, or HbSβ-thalassemia0), Sickle Cell Hemoglobin C Disease, Pain Crisis
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: Dilaudid Product, Dilaudid Injectable Product, Hydromorphone

Related On The Pen coverage

No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.