GLP-1 Market
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About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Diazoxide suspension, per kg per dose

Company
Columbia University
Mechanism
Mechanism not yet reported
Route
Oral
Recruiting trials
3 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

3 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Oct 1, 2026

Find a Clinical Trial Near Me

See recruiting studies for Diazoxide suspension, per kg per dose and check eligibility with the study team.

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Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT03540758

    Regulation of Endogenous Glucose Production by Central KATP Channels

    Not yet reported Albert Einstein College of Medicine 100 participants Est. completion 2027-04 1 site Stand-alone
    Other conditions: Diabetes Mellitus, Glucose Metabolism Disorders
    View official trial listing →
  • Recruiting NCT NCT04278404

    Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

    Duke University 5000 participants Est. completion 2026-12 52 sites
    Heart failure Other conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Hemophilia, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
    View official trial listing →
  • Recruiting NCT NCT07403604

    Effect of Insulin Lowering on Lipogenesis

    Not yet reported Columbia University 25 participants Est. completion 2029-09-30 1 site Stand-alone
    Other conditions: Hyperinsulinemia, Insulin Resistance, Non-Alcoholic Fatty Liver Disease, Prediabetic State, Obesity
    View official trial listing →
  • Completed NCT NCT00131755

    Efficacy of Diazoxide in Type 1 Diabetes

    Not yet reported Grill, Valdemar, M.D. 40 participants Est. completion 2008-08 1 site
    Other conditions: Diabetes Mellitus, Type 1
    View official trial listing →
  • Completed NCT NCT00151684

    Diazoxide-Mediated Insulin Suppression in Hyperinsulinemic Obese Men

    Not yet reported Rijnstate Hospital 25 participants 1 site
    Other conditions: Obesity, Hyperinsulinism
    View official trial listing →
  • Completed NCT NCT00184821

    Ischemic Injury and Ischemic Preconditioning in Diabetes

    Radboud University Medical Center 20 participants Est. completion 2005-05 1 site
    Other conditions: Diabetes Mellitus, Insulin-Dependent, Ischemia-Reperfusion Injury
    View official trial listing →
  • Completed NCT NCT00306683

    Effect of Diazoxide on the Obesity Secondary to Hypothalamic-pituitary Lesions

    Not yet reported Assistance Publique - Hôpitaux de Paris 40 participants Est. completion 2009-04 1 site
    Other conditions: Hypothalamic-pituitary Lesions, Craniopharyngiomas
    View official trial listing →
  • Completed NCT NCT00631033

    DZX Mediated Insulin Suppression in Obese Men

    Not yet reported Rijnstate Hospital 51 participants Est. completion 2011-12 1 site
    Other conditions: Obesity
    View official trial listing →
  • Completed NCT NCT00683774

    Insulin and Polycystic Ovary Syndrome

    Not yet reported Virginia Commonwealth University 21 participants Est. completion 2008-12 1 site
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT00688857

    Open-label Pharmacokinetic Study of Diazoxide Choline Coated vs. Uncoated Formulations

    Not yet reported Essentialis, Inc. 12 participants Est. completion 2008-07 1 site
    Other conditions: Hypertriglyceridemia
    View official trial listing →
  • Completed NCT NCT00696475

    Diazoxide Choline in Hypertriglyceridemia

    Not yet reported Essentialis, Inc. 80 participants Est. completion 2009-03 12 sites
    Other conditions: Hypertriglyceridemia
    View official trial listing →
  • Completed NCT NCT00892073

    Hypothalamic Obesity Following Craniopharyngioma Surgery: A Pilot Trial of Combined Metformin and Diazoxide Therapy

    Not yet reported The Hospital for Sick Children 9 participants Est. completion 2008-01 1 site
    Other conditions: Hypothalamic Obesity
    View official trial listing →
  • Withdrawn NCT NCT00901823

    Open-Label, Single- and Multiple-Dose Pharmacokinetic Study of Diazoxide Choline

    Not yet reported Essentialis, Inc. Est. completion 2011-03
    Other conditions: Hypertriglyceridemia
    View official trial listing →
  • Withdrawn NCT NCT00973271

    Diazoxide Choline Controlled-Release Tablet (DCCR) for Very High Triglycerides

    Not yet reported Essentialis, Inc. Est. completion 2011-12
    Other conditions: Hypertriglyceridemia
    View official trial listing →
  • Completed NCT NCT00989781

    Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary Syndrome

    Not yet reported University of California, San Diego 41 participants Est. completion 2013-09 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT00994149

    Diazoxide In the Management Of Hypoglycemic Neonates

    Not yet reported, Not yet reported University of Saskatchewan 100 participants Est. completion 2011-10 1 site
    Other conditions: Infant, Newborn, Diseases, Pregnancy in Diabetics, Infant, Diabetic Mother, Hypoglycemia, Infant, Large for Gestational Age
    View official trial listing →
  • Terminated NCT NCT01028846

    Central Mechanisms That Regulate Glucose Metabolism in Humans

    Not yet reported Meredith Hawkins 10 participants Est. completion 2007-12-05 1 site
    Type 2 diabetes Other conditions: Glucose Metabolism Disorders, Glucose, High Blood
    View official trial listing →
  • Completed NCT NCT01211847

    Efficacy Study of Diazoxide Choline to Treat Hypertriglyceridemia

    Not yet reported Essentialis, Inc. 44 participants Est. completion 2011-12
    Other conditions: Hypertriglyceridemia, Dyslipidemia
    View official trial listing →
  • Completed NCT NCT01211860

    Pharmacokinetic Study of Diazoxide Choline in Hypertriglyeridemic Subjects

    Not yet reported Essentialis, Inc. 9 participants Est. completion 2010-11 1 site
    Other conditions: Hypertriglyceridmia
    View official trial listing →
  • Completed NCT NCT01488136

    Use of Diazoxide in Acute Hypoglycaemia

    Not yet reported University of Dundee 12 participants Est. completion 2013-03 1 site
    Other conditions: Type 1 Diabetes
    View official trial listing →
  • Completed NCT NCT02034071

    Clinical Study of Diazoxide Choline Controlled-Release Tablet (DCCR) in Patients With Prader-Willi Syndrome

    Not yet reported, Not yet reported Essentialis, Inc. 13 participants Est. completion 2015-05 1 site
    Other conditions: Prader-Willi Syndrome
    View official trial listing →
  • Terminated NCT NCT02049385

    Does Enhanced Glutamate Transporter Function Produce Antidepressant Effects in People With Major Depression?

    Not yet reported, Not yet reported National Institute of Mental Health (NIMH) 10 participants Est. completion 2016-07-21 1 site
    Other conditions: Depression
    View official trial listing →
  • Withdrawn NCT NCT02779257

    Pasireotide Treatment for Neuroendocrine Tumor

    Not yet reported University of Maryland, Baltimore Est. completion 2016-06
    Other conditions: Gastro-enteropancreatic Neuroendocrine Tumor
    View official trial listing →
  • Status unknown NCT NCT02893618

    A 5 Treatment Period Pharmacokinetic Study Evaluating Dose Proportionality and Food Effects of Diazoxide Choline Controlled-Release Tablet (DCCR)

    Not yet reported Essentialis, Inc. 32 participants Est. completion 2017-12
    Other conditions: Prader-Willi Syndrome
    View official trial listing →
  • Completed NCT NCT03440814

    A Study of Diazoxide Choline in Patients With Prader-Willi Syndrome

    Not yet reported Soleno Therapeutics, Inc. 127 participants Est. completion 2020-05-01 29 sites
    Other conditions: Prader-Willi Syndrome
    View official trial listing →
  • Terminated NCT NCT03566511

    Use of Functional MRI to Assess Functional Hypothalamic Activation in Response to Diazoxide

    Not yet reported Meredith Hawkins 37 participants Est. completion 2020-08-01 1 site Stand-alone
    Type 2 diabetes Other conditions: Glucose, High Blood, Glucose Metabolism Disorders (Including Diabetes Mellitus)
    View official trial listing →
  • Terminated NCT NCT03608163

    Novel Approach for the Prevention of Hypoglycemia Associated Autonomic Failure (HAAF)

    Not yet reported Albert Einstein College of Medicine 4 participants Est. completion 2019-08-22 1 site
    Other conditions: Diabetes Mellitus, Type 1, Hypoglycemia, Hypoglycemia Unawareness
    View official trial listing →
  • Withdrawn NCT NCT03685773

    The Role of Hepatic Denervation in the Dysregulation of Glucose Metabolism in Liver Transplant Recipients

    Not yet reported Albert Einstein College of Medicine Est. completion 2023-04-21 1 site
    Type 2 diabetes Other conditions: Glucose, High Blood, Glucose Metabolism Disorders
    View official trial listing →
  • Completed NCT NCT03714373

    Open-Label Extension Study of DCCR in PWS Followed by Double-Blind, Placebo-Controlled, Randomized Withdrawal Period

    Not yet reported Soleno Therapeutics, Inc. 115 participants Est. completion 2023-08-17 28 sites
    Other conditions: Prader-Willi Syndrome
    View official trial listing →
  • Withdrawn NCT NCT04086810

    An Open-Label Study of DCCR Tablet in Patients With PWS

    Not yet reported Soleno Therapeutics, Inc. Est. completion 2019-10
    Other conditions: Prader-Willi Syndrome
    View official trial listing →
  • Withdrawn NCT NCT04830982

    Safety and Efficacy of IV Diazoxide as an Additive to Hyperkalemic Cardioplegia in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass

    Not yet reported Johns Hopkins University Est. completion 2025-10-30 1 site
    Other conditions: Myocardial Stunning
    View official trial listing →
  • Status unknown NCT NCT05532020

    An Open-Label Study of Diazoxide Choline in Patients With Genetic Obesities

    Not yet reported Soleno Therapeutics, Inc. 30 participants Est. completion 2024-03
    Other conditions: SH2B1 Deficiency Obesity, Obesity Associated With PCSK1 Mutation (rs6232 Variant), SIM1 Deficiency Obesity
    View official trial listing →
  • Active, not recruiting NCT NCT05701774

    Open-Label Extension Study of DCCR in Patients With Prader-Willi Syndrome

    Not yet reported Soleno Therapeutics, Inc. 83 participants Est. completion 2028-06 22 sites
    Other conditions: Prader-Willi Syndrome
    View official trial listing →
  • Completed NCT NCT05729282

    Glycemic Effect of Diazoxide in NAFLD

    Not yet reported Columbia University 22 participants Est. completion 2025-09-10 1 site Stand-alone
    Other conditions: Hyperinsulinemia, Insulin Resistance, Non-Alcoholic Fatty Liver Disease, Prediabetic State
    View official trial listing →
  • Status unknown NCT NCT06277947

    Administration of Hyperthermic Intraperitoneal Chemotherapy in the General Ward

    Not yet reported Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 92 participants Est. completion 2025-05 1 site
    Other conditions: Epithelial Ovarian Cancer
    View official trial listing →
  • Completed NCT NCT06308107

    Safety and Feasibility of Hyperkalemic Cardioplegia With Diazoxide in Cardiac Surgery (CPG-DZX) Trial

    Not yet reported Johns Hopkins University 30 participants Est. completion 2025-05-09 1 site
    Other conditions: Myocardial Stunning
    View official trial listing →
  • Terminated NCT NCT06606327

    Diazoxide Suppression Test P&F Study

    Not yet reported Columbia University 1 participants Est. completion 2026-06-10 1 site
    Other conditions: Insulin Resistance, Hyperinsulinemia, Obesity
    View official trial listing →
  • Enrolling by invitation NCT NCT07450664

    Observational Study of VYKAT™ XR in Patients With Prader-Willi Syndrome

    Soleno Therapeutics, Inc. 200 participants Est. completion 2028-03-02 24 sites
    Other conditions: Prader-Willi Syndrome
    View official trial listing →
  • Not yet recruiting NCT NCT07739394

    Diazoxide in the Treatment of Type 1 Glycogenosis

    Central Hospital, Nancy, France 15 participants Est. completion 2027-10-15
    Other conditions: Glycogen Storage Disease Type I
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: Diazoxide suspension, per kg per dose, Diazoxide oral suspension, 1 mg per kg per dose, Proglycem, Diazoxide oral suspension, 2 mg per kg per dose

Related On The Pen coverage

No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.