GLP-1 Market
LLY $1123.00 ▼ -0.1% NVO $44.01 ▼ -1.2% PFE $27.65 ▼ -0.5% VKTX $32.13 ▼ -1.7% KLRA $14.91 ▲ +0.5% GPCR $39.55 ▼ -4.1% RHHBY $53.19 ▼ -0.4% HIMS $27.44 ▼ -1.6% WW $14.78 ▼ -1.1%
Delayed · As of 9:20 AM
About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Diane-35

Company
Xiaojun Chen
Mechanism
Mechanism not yet reported
Route
Route not yet reported
Recruiting trials
5 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

5 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026

Find a Clinical Trial Near Me

See recruiting studies for Diane-35 and check eligibility with the study team.

Select conditions
Match
Treatment type

"Added to GLP-1" means the investigational treatment is being studied on top of an existing GLP-1-based therapy.

Your ZIP code is only used to calculate distance to trial sites — it isn't stored.

Trial details
  • Recruiting NCT NCT05316935

    GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients

    Not yet reported, Not yet reported Xiaojun Chen 80 participants Est. completion 2028-03-30 2 sites Stand-alone
    Other conditions: Endometrial Neoplasms, Atypical Endometrial Hyperplasia, Progesterone Resistance
    View official trial listing →
  • Recruiting NCT NCT05318755

    China Gender-affirming Hormone Therapy Study

    Peking University Third Hospital 240 participants Est. completion 2028-12-31 1 site
    Other conditions: Transgender, Gender Incongruence
    View official trial listing →
  • Recruiting NCT NCT06291675

    Gender-Affirming Hormone Therapy and Its Impact on Myocardial Mass and Cardiac Function, Heart, Liver and Pancreatic Fat Content

    Medical University of Vienna 50 participants Est. completion 2033-03-03 1 site
    Other conditions: Gender Dysphoria, Hormone Therapy Induced Morphologic Change
    View official trial listing →
  • Recruiting NCT NCT07115082

    Clinical Study on the Safety and Efficacy of Human Amniotic Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency

    Not yet reported, Not yet reported Yan Hongli 50 participants Est. completion 2026-03-30 1 site
    Other conditions: Premature Ovarian Insufficiency
    View official trial listing →
  • Recruiting NCT NCT07187947

    Cardiovascular Health of Transgender Individuals During the Gender-affirming Pathway

    IRCCS Azienda Ospedaliero-Universitaria di Bologna 500 participants Est. completion 2035-12-31 1 site
    Cardiovascular disease Other conditions: Gender Incongruence, Cardiovascular (CV) Risk, Cardiovascular Health Status
    View official trial listing →
  • Completed NCT NCT00003653

    Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer

    Not yet reported NCIC Clinical Trials Group 1386 participants Est. completion 2013-01-10 29 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00005623

    Cyproterone Acetate in Treating Hot Flashes Following Surgical or Chemical Castration for Prostate Cancer

    Not yet reported Barr Laboratories Est. completion 2004-01 1 site
    Other conditions: Hot Flashes, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00196339

    A Clinical Trial to Study DR-2031 for the Treatment of Hot Flashes in Prostate Cancer Patients

    Not yet reported Duramed Research 315 participants Est. completion 2008-01 118 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00280657

    Study on Safety and Efficacy of an Oral Contraceptive in Treating Acne Papulopustulosa

    Not yet reported Bayer 1326 participants Est. completion 2005-05-21 62 sites
    Other conditions: Acne Vulgaris
    View official trial listing →
  • Status unknown NCT NCT00363285

    Cyproterone Acetate in Treating Patients With Newly Diagnosed Stage III or Stage IV Prostate Cancer

    Not yet reported St. Bartholomew's Hospital 900 participants 2 sites
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00428311

    Effects of Metformin vs Oral Contraceptives on CV Risk Markers in PCOS

    Not yet reported Hospital Universitario Ramon y Cajal 50 participants Est. completion 2006-10 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Terminated NCT NCT00601276

    Comparison of Two Pharmacological Treatments of Pedophilia

    Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 48 participants Est. completion 2009-06 4 sites
    Other conditions: Pedophilia
    View official trial listing →
  • Completed NCT NCT00752635

    Comparison of Efficacy and Safety of Norgestimate-ethinyl Estradiol and Cyproterone Acetate-ethinyl Estradiol in the Treatment of Acne Vulgaris

    Not yet reported Johnson & Johnson Taiwan Ltd 48 participants Est. completion 2005-09
    Other conditions: Acne Vulgaris
    View official trial listing →
  • Completed NCT NCT00782847

    Evaluation Study for the Programme DiaNe for People With Diabetic Nephropathy

    Not yet reported DiaNe HCM GmbH 125 participants Est. completion 2007-01 1 site
    Chronic kidney disease
    View official trial listing →
  • Completed NCT NCT00849082

    Radiation Therapy With or Without Goserelin and Cyproterone in Treating Patients With Prostate Cancer

    Not yet reported European Organisation for Research and Treatment of Cancer - EORTC
    Other conditions: Prostate Cancer
    View official trial listing →
  • Completed NCT NCT00908674

    Androcur Effects on Quality of Life

    Bayer 245 participants Est. completion 2010-01 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Terminated NCT NCT00919022

    Androcur Non-interventional Study Among Patients With Carcinoma of the Prostate

    Bayer 194 participants Est. completion 2011-08 1 site
    Other conditions: Prostate Cancer
    View official trial listing →
  • Status unknown NCT NCT00955058

    Evaluation of Serum Prostatic Specific Antigen (PSA) After Cyproterone Compound Treatment Compared With Oral Contraceptives Pill in Hirsute Polycystic Ovary Syndrome Patients

    Not yet reported, Not yet reported Shahid Beheshti University 60 participants Est. completion 2010-12 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01011751

    Treatment of Hot Flushes Caused by Leuprorelin 11.25 mg in Prostate Adenocarcinoma

    Not yet reported Takeda 311 participants Est. completion 2007-12 1 site
    Other conditions: Adenocarcinoma, Prostate
    View official trial listing →
  • Completed NCT NCT01065220

    Sex Steroids and the Serotonin Transporter

    Not yet reported Medical University of Vienna 32 participants Est. completion 2014-01 1 site
    Other conditions: Transsexualism
    View official trial listing →
  • Status unknown NCT NCT01103518

    Ethinyl Estradiol and Cyproterone Acetate in Irregular Menstruation

    Not yet reported Fundação Educacional Serra dos Órgãos 100 participants Est. completion 2011-01 1 site
    Other conditions: Amenorrhea, Dysmenorrhea, Menstruation Disturbances, Hyperandrogenism
    View official trial listing →
  • Completed NCT NCT01292785

    Effects of Sex Steroid Hormones on Human Brain Function, Structure and Connectivity

    Medical University of Vienna 80 participants Est. completion 2015-04 1 site
    Other conditions: Gender Identity Disorder
    View official trial listing →
  • Completed NCT NCT01573377

    Efficacy of Metformin and Diane-35 on PCOS Patients,a Randomized, Controlled, Prospective Clinical Trial

    Not yet reported Chongqing Medical University 40 participants Est. completion 2013-02 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome, Insulin Resistance
    View official trial listing →
  • Status unknown NCT NCT01752270

    the Effect of Diane-35 Pretreatment on In-vitro Fertilization Outcome for Patients With Polycystic Ovary Syndrome

    Not yet reported First Affiliated Hospital, Sun Yat-Sen University 100 participants Est. completion 2014-12 2 sites Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT01784380

    The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome

    Zhongshan Bo Ai Hospital 1159 participants Est. completion 2012-10 2 sites
    Other conditions: The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;, At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;, 534 Patients in the Cases Group and 580 Women in the Control Group Received no Measures, While 579 Patients Received Drugs;, The Investigators Monitored Basic Indexes in Blood of All the Subjects in This Suvey,and Also Monitored Indexes of 579 Patients After Treatment.
    View official trial listing →
  • Status unknown NCT NCT01798875

    PCOS, Therapy and Markers of Cardiovascular Risk

    Not yet reported Medical University of Gdansk 50 participants Est. completion 2015-12 1 site
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT01819285

    Early Compared With Delayed Hormone Therapy in Treating Patients With Nonmetastatic Prostate Cancer

    Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 985 participants Est. completion 2010-09
    Other conditions: Neoplasm, Prostate
    View official trial listing →
  • Status unknown NCT NCT01874379

    'M'-Technique, Guided Imagery, or Standard of Care on Anxiety and Pain Pre- & Post-operatively in Elective Joint Replacement Patients

    Not yet reported Saint Clare's Health System 225 participants 1 site
    Other conditions: Hip or Knee Replacement
    View official trial listing →
  • Completed NCT NCT01933204

    Acupuncture for Relieving Perimenopausal Symptoms

    Not yet reported, Not yet reported Chengdu University of Traditional Chinese Medicine 220 participants Est. completion 2015-08 2 sites
    Other conditions: Perimenopause
    View official trial listing →
  • Completed NCT NCT01973816

    MEdical Versus SUrgical Treatments of Rectal Endometriosis

    Not yet reported University Hospital, Rouen 78 participants Est. completion 2022-10-11 11 sites
    Other conditions: Endometriosis
    View official trial listing →
  • Status unknown NCT NCT02027337

    Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants

    Not yet reported Tyumen State Medical Academy 200 participants Est. completion 2015-10 1 site
    Other conditions: Polycystic Ovarian Syndrome, Hyperandrogenism, Menstrual Irregularities
    View official trial listing →
  • Completed NCT NCT02349399

    Drug Utilization Study on Diane-35 (and Generics) in Three European Healthcare Databases

    Bayer 26065 participants Est. completion 2016-03-01 3 sites
    Other conditions: Acne Vulgaris
    View official trial listing →
  • Completed NCT NCT02410031

    Risk Minimisation Study for Diane-35 and Its Generics

    Bayer 759 participants Est. completion 2016-03-04 5 sites
    Other conditions: Acne Vulgaris
    View official trial listing →
  • Completed NCT NCT02460445

    Phlebotomy and Polycystic Ovary Syndrome

    Not yet reported Manuel Luque Ramírez 37 participants Est. completion 2020-06 1 site Stand-alone
    Other conditions: Hyperandrogenism, Metabolic Cardiovascular Syndrome
    View official trial listing →
  • Completed NCT NCT02494297

    DUS on the Prescribing Indications for CPA/EE in 5 European Countries

    Center for Epidemiology and Health Research, Germany 1597 participants Est. completion 2016-10-31 1 site
    Other conditions: Hirsutism, Androgenetic Alopecia, Severe Anemia, Seborrhea, PCOS
    View official trial listing →
  • Suspended NCT NCT02599077

    Impact vs. Dienogest: A Combined Oral Contraceptive in the Size of Endometriomas

    Not yet reported, Not yet reported Fundación Santa Fe de Bogota 50 participants Est. completion 2018-11 1 site
    Other conditions: Endometriosis
    View official trial listing →
  • Completed NCT NCT02636972

    The Progression From Dysmenorrhoea to Chronic Pelvic Pain

    University of Adelaide 56 participants Est. completion 2016-01 1 site
    Other conditions: Dysmenorrhoea, Pelvic Pain, Chronic Pain
    View official trial listing →
  • Completed NCT NCT02689843

    Effects of Cyproterone Compound-spironolactone, Metformin and Pioglitazone on Inflammatory Markers in PCOS

    Not yet reported Shiraz University of Medical Sciences 90 participants Est. completion 2018-12-30 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Status unknown NCT NCT02715232

    Effects of Sex Steroids on the Serotonin System

    Not yet reported Medical University of Vienna 92 participants Est. completion 2020-12 1 site
    Other conditions: Gender Dysphoria
    View official trial listing →
  • Completed NCT NCT02729545

    The Efficacy and Safety Study of Tung's Acupuncture for Polycystic Ovarian Syndrome

    Not yet reported Beijing Hospital of Integrated Traditional Chinese and Western Medicine 60 participants Est. completion 2018-05 1 site
    Other conditions: Polycystic Ovarian Syndrome
    View official trial listing →
  • Status unknown NCT NCT02744131

    OCP vs Metformin for Improvement in Clinical Symptoms and Metabolic Markers in Indian PCOS Women

    Not yet reported Kar Clinic & Hospital Pvt. Ltd. 100 participants Est. completion 2019-12 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02866786

    The Effects of OCP and Metformin on Clinical, Hormonal, Metabolic and Ultrasonographic Characteristics in PCOS

    Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2017-08-01 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT02991274

    ARTEMIS DIANE T790M (An Amino Acid Substitution at Position 790 in EGFR, From a Threonine (T) to a Methionine (M)) Mutation at Hospital Laboratories in Comparison With Central Laboratory

    AstraZeneca 897 participants Est. completion 2018-06-29 31 sites
    Other conditions: Locally Advanced or Metastatic EGFR(+) NSCLC Patients
    View official trial listing →
  • Completed NCT NCT03043924

    Functional Study of the Hypothalamus in Magnetic Resonance Imaging (MRI) in Polycystic Ovary Syndrome (PCOS)

    Not yet reported University Hospital, Lille 52 participants Est. completion 2022-04-15 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT03151005

    The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS

    Not yet reported Xinqiao Hospital of Chongqing 70 participants Est. completion 2021-04-23 1 site
    Other conditions: Polycystic Ovary Syndrome (PCOS), Overweight, Obesity
    View official trial listing →
  • Completed NCT NCT03236740

    OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS

    Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2018-03-15 1 site
    Other conditions: PCOS
    View official trial listing →
  • Status unknown NCT NCT03264638

    A Clinical and Biological Research of Combined Chinese and Western Medicine in the Treatment of PCOS

    Not yet reported Aijun Sun 315 participants Est. completion 2018-08-31 1 site Stand-alone
    Other conditions: PCOS
    View official trial listing →
  • Completed NCT NCT03303482

    A Randomized Controlled Trial of Trauma-awareness Training for Early Childhood Educators

    Not yet reported Temple University 96 participants Est. completion 2018-05-21 1 site
    Other conditions: Burnout, Professional
    View official trial listing →
  • Status unknown NCT NCT04029272

    Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients

    Not yet reported Peking Union Medical College Hospital 80 participants Est. completion 2020-12-31 1 site Added to GLP-1
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04109404

    Meningiomas and Treatment With CYPROTERONE ACETATE or Progestin

    University Hospital, Brest 110 participants Est. completion 2019-06-01 1 site
    Other conditions: Meningioma
    View official trial listing →
  • Status unknown NCT NCT04372095

    Androcur® (Cyproterone Acetate) and Meningioma Development: a Genotype-environment Association Study

    Assistance Publique - Hôpitaux de Paris 2000 participants Est. completion 2025-04-19 1 site
    Other conditions: Meningioma
    View official trial listing →
  • Active, not recruiting NCT NCT04590417

    Assessment of Drug-drug Interactions Between Feminizing Hormone Therapy and Emtricitabine/Tenofovir Alafenamide Concomitantly for Pre-exposure Prophylaxis Among Transgender Women

    Not yet reported Thai Red Cross AIDS Research Centre 20 participants Est. completion 2025-10-01 1 site
    Other conditions: Drug Interaction
    View official trial listing →
  • Status unknown NCT NCT04831151

    The Effect of Polycystic Ovary Syndrome Treatment on Metabolomics

    Not yet reported Inonu University 42 participants Est. completion 2023-06 1 site
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT04848181

    The Effect of Pre-operative Use of Finasteride Versus Cyproterone Acetate on Blood Loss With Transurethral Resection of Prostate

    Not yet reported Benha University 60 participants Est. completion 2020-07-09 1 site
    Other conditions: Prostate Hyperplasia
    View official trial listing →
  • Completed NCT NCT04925180

    A Study to Learn About the Awareness and Knowledge That Doctors Have About the Safety and Safe Use Information for Androcur and Other Cyproterone Acetate Treatments in Europe

    Bayer 600 participants Est. completion 2021-12-31 5 sites
    Other conditions: Signs of Androgenisation in Women, e.g. Hirsutism, Androgenetic Alopecia, Acne and Seborrhea, Hypersexuality in Men, Sexual Deviations in Men, Prostate Cancer
    View official trial listing →
  • Completed NCT NCT04964193

    Bioequivalence Study of Cyproterone Acetate and Ethinyl Estradiol in Healthy Female Volunteers

    Not yet reported PT Sydna Farma 24 participants Est. completion 2019-09-26 1 site
    Other conditions: Drug Use
    View official trial listing →
  • Status unknown NCT NCT04984070

    Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety

    Not yet reported Fudan University 100 participants Est. completion 2024-12-31 1 site
    Other conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety
    View official trial listing →
  • Status unknown NCT NCT05021861

    Evaluation of Periodontal Status and hsCRP Levels in Females With PCOS on CPA/EE Combination Drug Regimen

    Postgraduate Institute of Dental Sciences Rohtak 150 participants Est. completion 2022-09-30 1 site
    Other conditions: Periodontitis, Polycystic Ovary Syndrome, Gingivitis
    View official trial listing →
  • Completed NCT NCT05147012

    Intraoperative Hypotension Predicted by Mean Arterial Pressure

    Hospices Civils de Lyon 80 participants Est. completion 2020-03-31 1 site
    Other conditions: Wedge Resection, Lobectomy by Video-thoracoscopies
    View official trial listing →
  • Completed NCT NCT05149131

    A Study Called AWARENESS Using Data From Men in Alberta to Observe Treatment Patterns for Metastatic Castration-sensitive Prostate Cancer

    Bayer 960 participants Est. completion 2022-08-16 1 site
    Other conditions: Metastatic Castration-sensitive Prostate Cancer
    View official trial listing →
  • Completed NCT NCT05657171

    "Effect of CPA/EE Drug on Periodontal Tissue and hsCRP Levels in PCOS Patients With Gingivitis

    Postgraduate Institute of Dental Sciences Rohtak 47 participants Est. completion 2023-12-30 1 site
    Other conditions: Periodontal Diseases
    View official trial listing →
  • Active, not recruiting NCT NCT05663892

    Drug-Drug Interaction Study in Trans Women Living With HIV

    Not yet reported Maple Leaf Research 45 participants Est. completion 2025-01 1 site
    Other conditions: Hiv, Transgenderism
    View official trial listing →
  • Status unknown NCT NCT06823830

    Clinical、metabolomics and the Study of Intestinal Flora of Jinfeng Pills in the Treatment of Polycystic Ovary Syndrome

    Not yet reported Peking Union Medical College Hospital 105 participants Est. completion 2025-02-28 1 site Stand-alone
    Other conditions: Polycystic Ovary Syndrome
    View official trial listing →
  • Completed NCT NCT07145281

    Comparing the Effects of Sublingual Estradiol Treatment Versus Oral Estradiol With Cyproterone Acetate (CPA) Treatment on The Coagulation System in Transgender Women: A Prospective, Controlled Cohort Study

    Not yet reported Tel-Aviv Sourasky Medical Center 30 participants Est. completion 2024-11-10 1 site
    Other conditions: Gender Dysphoria, Adult, Blood Coagulation, Coagulation Factors, Transgender Persons, M01.777.500, Hemostasis, Transgender Women
    View official trial listing →
  • Completed NCT NCT07513480

    Pretreatment With CPA-EE, Metformin and Myoinositol in PCOS With High AMH

    Not yet reported Mst.Sumyara Khatun 68 participants Est. completion 2026-02-20 1 site
    Other conditions: PCOS
    View official trial listing →
  • Not yet recruiting NCT NCT07714616

    Evaluation of the Contraceptive Efficacy and Safety of a New Concentration of an Antiandrogenic Progestogen Combined With a Reduced-Dose Estrogen (LUNA)

    Not yet reported Eurofarma Laboratorios S.A. 1600 participants Est. completion 2030-05-31
    Other conditions: Contraception
    View official trial listing →
Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

Also known as: Diane-35, ethinylestradiol cyproterone

Related On The Pen coverage

No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.