About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Diane-35
- Company
- Xiaojun Chen
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 5 recruiting
Efficacy results: Not yet reported
5 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Sep 11, 2026
Find a Clinical Trial Near Me
See recruiting studies for Diane-35 and check eligibility with the study team.
Trial details
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Recruiting NCT NCT05316935
GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients
Not yet reported, Not yet reported Xiaojun Chen 80 participants Est. completion 2028-03-30 2 sites Stand-aloneOther conditions: Endometrial Neoplasms, Atypical Endometrial Hyperplasia, Progesterone ResistanceView official trial listing → -
Recruiting NCT NCT05318755
China Gender-affirming Hormone Therapy Study
Peking University Third Hospital 240 participants Est. completion 2028-12-31 1 siteOther conditions: Transgender, Gender IncongruenceView official trial listing → -
Recruiting NCT NCT06291675
Gender-Affirming Hormone Therapy and Its Impact on Myocardial Mass and Cardiac Function, Heart, Liver and Pancreatic Fat Content
Medical University of Vienna 50 participants Est. completion 2033-03-03 1 siteOther conditions: Gender Dysphoria, Hormone Therapy Induced Morphologic ChangeView official trial listing → -
Recruiting NCT NCT07115082
Clinical Study on the Safety and Efficacy of Human Amniotic Mesenchymal Stem Cells in the Treatment of Premature Ovarian Insufficiency
Not yet reported, Not yet reported Yan Hongli 50 participants Est. completion 2026-03-30 1 siteOther conditions: Premature Ovarian InsufficiencyView official trial listing → -
Recruiting NCT NCT07187947
Cardiovascular Health of Transgender Individuals During the Gender-affirming Pathway
IRCCS Azienda Ospedaliero-Universitaria di Bologna 500 participants Est. completion 2035-12-31 1 siteCardiovascular disease Other conditions: Gender Incongruence, Cardiovascular (CV) Risk, Cardiovascular Health StatusView official trial listing → -
Completed NCT NCT00003653
Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer
Not yet reported NCIC Clinical Trials Group 1386 participants Est. completion 2013-01-10 29 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00005623
Cyproterone Acetate in Treating Hot Flashes Following Surgical or Chemical Castration for Prostate Cancer
Not yet reported Barr Laboratories Est. completion 2004-01 1 siteOther conditions: Hot Flashes, Prostate CancerView official trial listing → -
Completed NCT NCT00196339
A Clinical Trial to Study DR-2031 for the Treatment of Hot Flashes in Prostate Cancer Patients
Not yet reported Duramed Research 315 participants Est. completion 2008-01 118 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00280657
Study on Safety and Efficacy of an Oral Contraceptive in Treating Acne Papulopustulosa
Not yet reported Bayer 1326 participants Est. completion 2005-05-21 62 sitesOther conditions: Acne VulgarisView official trial listing → -
Status unknown NCT NCT00363285
Cyproterone Acetate in Treating Patients With Newly Diagnosed Stage III or Stage IV Prostate Cancer
Not yet reported St. Bartholomew's Hospital 900 participants 2 sitesOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00428311
Effects of Metformin vs Oral Contraceptives on CV Risk Markers in PCOS
Not yet reported Hospital Universitario Ramon y Cajal 50 participants Est. completion 2006-10 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Terminated NCT NCT00601276
Comparison of Two Pharmacological Treatments of Pedophilia
Not yet reported Institut National de la Santé Et de la Recherche Médicale, France 48 participants Est. completion 2009-06 4 sitesOther conditions: PedophiliaView official trial listing → -
Completed NCT NCT00752635
Comparison of Efficacy and Safety of Norgestimate-ethinyl Estradiol and Cyproterone Acetate-ethinyl Estradiol in the Treatment of Acne Vulgaris
Not yet reported Johnson & Johnson Taiwan Ltd 48 participants Est. completion 2005-09Other conditions: Acne VulgarisView official trial listing → -
Completed NCT NCT00782847
Evaluation Study for the Programme DiaNe for People With Diabetic Nephropathy
Not yet reported DiaNe HCM GmbH 125 participants Est. completion 2007-01 1 siteChronic kidney diseaseView official trial listing → -
Completed NCT NCT00849082
Radiation Therapy With or Without Goserelin and Cyproterone in Treating Patients With Prostate Cancer
Not yet reported European Organisation for Research and Treatment of Cancer - EORTCOther conditions: Prostate CancerView official trial listing → -
Completed NCT NCT00908674
Androcur Effects on Quality of Life
Bayer 245 participants Est. completion 2010-01 1 siteOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT00919022
Androcur Non-interventional Study Among Patients With Carcinoma of the Prostate
Bayer 194 participants Est. completion 2011-08 1 siteOther conditions: Prostate CancerView official trial listing → -
Status unknown NCT NCT00955058
Evaluation of Serum Prostatic Specific Antigen (PSA) After Cyproterone Compound Treatment Compared With Oral Contraceptives Pill in Hirsute Polycystic Ovary Syndrome Patients
Not yet reported, Not yet reported Shahid Beheshti University 60 participants Est. completion 2010-12 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01011751
Treatment of Hot Flushes Caused by Leuprorelin 11.25 mg in Prostate Adenocarcinoma
Not yet reported Takeda 311 participants Est. completion 2007-12 1 siteOther conditions: Adenocarcinoma, ProstateView official trial listing → -
Completed NCT NCT01065220
Sex Steroids and the Serotonin Transporter
Not yet reported Medical University of Vienna 32 participants Est. completion 2014-01 1 siteOther conditions: TranssexualismView official trial listing → -
Status unknown NCT NCT01103518
Ethinyl Estradiol and Cyproterone Acetate in Irregular Menstruation
Not yet reported Fundação Educacional Serra dos Órgãos 100 participants Est. completion 2011-01 1 siteOther conditions: Amenorrhea, Dysmenorrhea, Menstruation Disturbances, HyperandrogenismView official trial listing → -
Completed NCT NCT01292785
Effects of Sex Steroid Hormones on Human Brain Function, Structure and Connectivity
Medical University of Vienna 80 participants Est. completion 2015-04 1 siteOther conditions: Gender Identity DisorderView official trial listing → -
Completed NCT NCT01573377
Efficacy of Metformin and Diane-35 on PCOS Patients,a Randomized, Controlled, Prospective Clinical Trial
Not yet reported Chongqing Medical University 40 participants Est. completion 2013-02 1 site Stand-aloneOther conditions: Polycystic Ovary Syndrome, Insulin ResistanceView official trial listing → -
Status unknown NCT NCT01752270
the Effect of Diane-35 Pretreatment on In-vitro Fertilization Outcome for Patients With Polycystic Ovary Syndrome
Not yet reported First Affiliated Hospital, Sun Yat-Sen University 100 participants Est. completion 2014-12 2 sites Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT01784380
The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome
Zhongshan Bo Ai Hospital 1159 participants Est. completion 2012-10 2 sitesOther conditions: The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;, At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;, 534 Patients in the Cases Group and 580 Women in the Control Group Received no Measures, While 579 Patients Received Drugs;, The Investigators Monitored Basic Indexes in Blood of All the Subjects in This Suvey,and Also Monitored Indexes of 579 Patients After Treatment.View official trial listing → -
Status unknown NCT NCT01798875
PCOS, Therapy and Markers of Cardiovascular Risk
Not yet reported Medical University of Gdansk 50 participants Est. completion 2015-12 1 siteOther conditions: PCOSView official trial listing → -
Completed NCT NCT01819285
Early Compared With Delayed Hormone Therapy in Treating Patients With Nonmetastatic Prostate Cancer
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 985 participants Est. completion 2010-09Other conditions: Neoplasm, ProstateView official trial listing → -
Status unknown NCT NCT01874379
'M'-Technique, Guided Imagery, or Standard of Care on Anxiety and Pain Pre- & Post-operatively in Elective Joint Replacement Patients
Not yet reported Saint Clare's Health System 225 participants 1 siteOther conditions: Hip or Knee ReplacementView official trial listing → -
Completed NCT NCT01933204
Acupuncture for Relieving Perimenopausal Symptoms
Not yet reported, Not yet reported Chengdu University of Traditional Chinese Medicine 220 participants Est. completion 2015-08 2 sitesOther conditions: PerimenopauseView official trial listing → -
Completed NCT NCT01973816
MEdical Versus SUrgical Treatments of Rectal Endometriosis
Not yet reported University Hospital, Rouen 78 participants Est. completion 2022-10-11 11 sitesOther conditions: EndometriosisView official trial listing → -
Status unknown NCT NCT02027337
Hemocoagulation and Lipoperoxidation in Women Using Combined Oral Contraceptives, Correction by Antioxidants
Not yet reported Tyumen State Medical Academy 200 participants Est. completion 2015-10 1 siteOther conditions: Polycystic Ovarian Syndrome, Hyperandrogenism, Menstrual IrregularitiesView official trial listing → -
Completed NCT NCT02349399
Drug Utilization Study on Diane-35 (and Generics) in Three European Healthcare Databases
Bayer 26065 participants Est. completion 2016-03-01 3 sitesOther conditions: Acne VulgarisView official trial listing → -
Completed NCT NCT02410031
Risk Minimisation Study for Diane-35 and Its Generics
Bayer 759 participants Est. completion 2016-03-04 5 sitesOther conditions: Acne VulgarisView official trial listing → -
Completed NCT NCT02460445
Phlebotomy and Polycystic Ovary Syndrome
Not yet reported Manuel Luque Ramírez 37 participants Est. completion 2020-06 1 site Stand-aloneOther conditions: Hyperandrogenism, Metabolic Cardiovascular SyndromeView official trial listing → -
Completed NCT NCT02494297
DUS on the Prescribing Indications for CPA/EE in 5 European Countries
Center for Epidemiology and Health Research, Germany 1597 participants Est. completion 2016-10-31 1 siteOther conditions: Hirsutism, Androgenetic Alopecia, Severe Anemia, Seborrhea, PCOSView official trial listing → -
Suspended NCT NCT02599077
Impact vs. Dienogest: A Combined Oral Contraceptive in the Size of Endometriomas
Not yet reported, Not yet reported Fundación Santa Fe de Bogota 50 participants Est. completion 2018-11 1 siteOther conditions: EndometriosisView official trial listing → -
Completed NCT NCT02636972
The Progression From Dysmenorrhoea to Chronic Pelvic Pain
University of Adelaide 56 participants Est. completion 2016-01 1 siteOther conditions: Dysmenorrhoea, Pelvic Pain, Chronic PainView official trial listing → -
Completed NCT NCT02689843
Effects of Cyproterone Compound-spironolactone, Metformin and Pioglitazone on Inflammatory Markers in PCOS
Not yet reported Shiraz University of Medical Sciences 90 participants Est. completion 2018-12-30 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Status unknown NCT NCT02715232
Effects of Sex Steroids on the Serotonin System
Not yet reported Medical University of Vienna 92 participants Est. completion 2020-12 1 siteOther conditions: Gender DysphoriaView official trial listing → -
Completed NCT NCT02729545
The Efficacy and Safety Study of Tung's Acupuncture for Polycystic Ovarian Syndrome
Not yet reported Beijing Hospital of Integrated Traditional Chinese and Western Medicine 60 participants Est. completion 2018-05 1 siteOther conditions: Polycystic Ovarian SyndromeView official trial listing → -
Status unknown NCT NCT02744131
OCP vs Metformin for Improvement in Clinical Symptoms and Metabolic Markers in Indian PCOS Women
Not yet reported Kar Clinic & Hospital Pvt. Ltd. 100 participants Est. completion 2019-12 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02866786
The Effects of OCP and Metformin on Clinical, Hormonal, Metabolic and Ultrasonographic Characteristics in PCOS
Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2017-08-01 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT02991274
ARTEMIS DIANE T790M (An Amino Acid Substitution at Position 790 in EGFR, From a Threonine (T) to a Methionine (M)) Mutation at Hospital Laboratories in Comparison With Central Laboratory
AstraZeneca 897 participants Est. completion 2018-06-29 31 sitesOther conditions: Locally Advanced or Metastatic EGFR(+) NSCLC PatientsView official trial listing → -
Completed NCT NCT03043924
Functional Study of the Hypothalamus in Magnetic Resonance Imaging (MRI) in Polycystic Ovary Syndrome (PCOS)
Not yet reported University Hospital, Lille 52 participants Est. completion 2022-04-15 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT03151005
The Effect of GLP-1 Agonists Versus OCs on Reproductive Disorders and Cardiovascular Risks in Overweight PCOS
Not yet reported Xinqiao Hospital of Chongqing 70 participants Est. completion 2021-04-23 1 siteOther conditions: Polycystic Ovary Syndrome (PCOS), Overweight, ObesityView official trial listing → -
Completed NCT NCT03236740
OCP vs Metformin on Ovarian Stromal Blood Flow in PCOS
Not yet reported S.C.B. Medical College and Hospital 101 participants Est. completion 2018-03-15 1 siteOther conditions: PCOSView official trial listing → -
Status unknown NCT NCT03264638
A Clinical and Biological Research of Combined Chinese and Western Medicine in the Treatment of PCOS
Not yet reported Aijun Sun 315 participants Est. completion 2018-08-31 1 site Stand-aloneOther conditions: PCOSView official trial listing → -
Completed NCT NCT03303482
A Randomized Controlled Trial of Trauma-awareness Training for Early Childhood Educators
Not yet reported Temple University 96 participants Est. completion 2018-05-21 1 siteOther conditions: Burnout, ProfessionalView official trial listing → -
Status unknown NCT NCT04029272
Metformin vs Metformin Combined With GLP-1RA (Glucagon-like Peptide 1 Receptor Agonist) on Overweight/Obese PCOS Patients
Not yet reported Peking Union Medical College Hospital 80 participants Est. completion 2020-12-31 1 site Added to GLP-1Other conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04109404
Meningiomas and Treatment With CYPROTERONE ACETATE or Progestin
University Hospital, Brest 110 participants Est. completion 2019-06-01 1 siteOther conditions: MeningiomaView official trial listing → -
Status unknown NCT NCT04372095
Androcur® (Cyproterone Acetate) and Meningioma Development: a Genotype-environment Association Study
Assistance Publique - Hôpitaux de Paris 2000 participants Est. completion 2025-04-19 1 siteOther conditions: MeningiomaView official trial listing → -
Active, not recruiting NCT NCT04590417
Assessment of Drug-drug Interactions Between Feminizing Hormone Therapy and Emtricitabine/Tenofovir Alafenamide Concomitantly for Pre-exposure Prophylaxis Among Transgender Women
Not yet reported Thai Red Cross AIDS Research Centre 20 participants Est. completion 2025-10-01 1 siteOther conditions: Drug InteractionView official trial listing → -
Status unknown NCT NCT04831151
The Effect of Polycystic Ovary Syndrome Treatment on Metabolomics
Not yet reported Inonu University 42 participants Est. completion 2023-06 1 siteOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT04848181
The Effect of Pre-operative Use of Finasteride Versus Cyproterone Acetate on Blood Loss With Transurethral Resection of Prostate
Not yet reported Benha University 60 participants Est. completion 2020-07-09 1 siteOther conditions: Prostate HyperplasiaView official trial listing → -
Completed NCT NCT04925180
A Study to Learn About the Awareness and Knowledge That Doctors Have About the Safety and Safe Use Information for Androcur and Other Cyproterone Acetate Treatments in Europe
Bayer 600 participants Est. completion 2021-12-31 5 sitesOther conditions: Signs of Androgenisation in Women, e.g. Hirsutism, Androgenetic Alopecia, Acne and Seborrhea, Hypersexuality in Men, Sexual Deviations in Men, Prostate CancerView official trial listing → -
Completed NCT NCT04964193
Bioequivalence Study of Cyproterone Acetate and Ethinyl Estradiol in Healthy Female Volunteers
Not yet reported PT Sydna Farma 24 participants Est. completion 2019-09-26 1 siteOther conditions: Drug UseView official trial listing → -
Status unknown NCT NCT04984070
Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety
Not yet reported Fudan University 100 participants Est. completion 2024-12-31 1 siteOther conditions: PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, AnxietyView official trial listing → -
Status unknown NCT NCT05021861
Evaluation of Periodontal Status and hsCRP Levels in Females With PCOS on CPA/EE Combination Drug Regimen
Postgraduate Institute of Dental Sciences Rohtak 150 participants Est. completion 2022-09-30 1 siteOther conditions: Periodontitis, Polycystic Ovary Syndrome, GingivitisView official trial listing → -
Completed NCT NCT05147012
Intraoperative Hypotension Predicted by Mean Arterial Pressure
Hospices Civils de Lyon 80 participants Est. completion 2020-03-31 1 siteOther conditions: Wedge Resection, Lobectomy by Video-thoracoscopiesView official trial listing → -
Completed NCT NCT05149131
A Study Called AWARENESS Using Data From Men in Alberta to Observe Treatment Patterns for Metastatic Castration-sensitive Prostate Cancer
Bayer 960 participants Est. completion 2022-08-16 1 siteOther conditions: Metastatic Castration-sensitive Prostate CancerView official trial listing → -
Completed NCT NCT05657171
"Effect of CPA/EE Drug on Periodontal Tissue and hsCRP Levels in PCOS Patients With Gingivitis
Postgraduate Institute of Dental Sciences Rohtak 47 participants Est. completion 2023-12-30 1 siteOther conditions: Periodontal DiseasesView official trial listing → -
Active, not recruiting NCT NCT05663892
Drug-Drug Interaction Study in Trans Women Living With HIV
Not yet reported Maple Leaf Research 45 participants Est. completion 2025-01 1 siteOther conditions: Hiv, TransgenderismView official trial listing → -
Status unknown NCT NCT06823830
Clinical、metabolomics and the Study of Intestinal Flora of Jinfeng Pills in the Treatment of Polycystic Ovary Syndrome
Not yet reported Peking Union Medical College Hospital 105 participants Est. completion 2025-02-28 1 site Stand-aloneOther conditions: Polycystic Ovary SyndromeView official trial listing → -
Completed NCT NCT07145281
Comparing the Effects of Sublingual Estradiol Treatment Versus Oral Estradiol With Cyproterone Acetate (CPA) Treatment on The Coagulation System in Transgender Women: A Prospective, Controlled Cohort Study
Not yet reported Tel-Aviv Sourasky Medical Center 30 participants Est. completion 2024-11-10 1 siteOther conditions: Gender Dysphoria, Adult, Blood Coagulation, Coagulation Factors, Transgender Persons, M01.777.500, Hemostasis, Transgender WomenView official trial listing → -
Completed NCT NCT07513480
Pretreatment With CPA-EE, Metformin and Myoinositol in PCOS With High AMH
Not yet reported Mst.Sumyara Khatun 68 participants Est. completion 2026-02-20 1 siteOther conditions: PCOSView official trial listing → -
Not yet recruiting NCT NCT07714616
Evaluation of the Contraceptive Efficacy and Safety of a New Concentration of an Antiandrogenic Progestogen Combined With a Reduced-Dose Estrogen (LUNA)
Not yet reported Eurofarma Laboratorios S.A. 1600 participants Est. completion 2030-05-31Other conditions: ContraceptionView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Diane-35, ethinylestradiol cyproterone
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
