Deuterated water

• Recruiting NCT NCT05743868

  Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance Phenotypes

  Not yet reported Yale University 40 participants Est. completion 2026-06 1 site Stand-alone
  Other conditions: Insulin Resistance, Hypertriglyceridemia
  View official trial listing →
• Recruiting NCT NCT06269653

  Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide

  National Institute on Aging (NIA) 75 participants Est. completion 2027-03-01 1 site
  Other conditions: Healthy Volunteers
  View official trial listing →
• Recruiting NCT NCT06602141

  Assessments of Adipogenesis, Lipid Turnover and Cellular Composition in Adipose Tissue in Response to Endurance Exercise

  Not yet reported AdventHealth Translational Research Institute 70 participants Est. completion 2029-04 2 sites
  Other conditions: Obesity
  View official trial listing →
• Recruiting NCT NCT07403604

  Effect of Insulin Lowering on Lipogenesis

  Not yet reported Columbia University 25 participants Est. completion 2029-09-30 1 site Stand-alone
  Other conditions: Hyperinsulinemia, Insulin Resistance, Non-Alcoholic Fatty Liver Disease, Prediabetic State, Obesity
  View official trial listing →
• Completed NCT NCT00560469

  Impaired Adipogenesis in Insulin Resistance: Pilot Clinical and In Vitro Studies

  University of Vermont 20 participants Est. completion 2010-07 1 site
  Other conditions: Adipocyte Differentiation, Insulin Resistance
  View official trial listing →
• Terminated NCT NCT00962234

  Metabolism of Lipids in Advanced Cancer

  AHS Cancer Control Alberta 12 participants Est. completion 2011-10 1 site
  Other conditions: Lung Neoplasms, Cachexia
  View official trial listing →
• Status unknown NCT NCT00990379

  Using Heavy Water to Study Cell Dynamics in Parkinson's Disease

  Salena Killion 45 participants Est. completion 2016-02 1 site
  Other conditions: Parkinson's Disease, HIV Infections
  View official trial listing →
• Completed NCT NCT01110850

  Direct Measurement of Leukemic Cell Turnover (Synthesis and Removal) in Patients With Chronic Lymphocytic Leukemia (CLL) Using Deuterated Water

  Northwell Health 24 participants Est. completion 2018-05-23 1 site
  Other conditions: Chronic Lymphocytic Leukemia
  View official trial listing →
• Completed NCT NCT01209936

  Hydration Factor Study for the Stayhealthy BC3

  Not yet reported University of Southern California 360 participants Est. completion 2010-07 1 site
  Other conditions: Body Composition
  View official trial listing →
• Completed NCT NCT01290055

  Turnover of Antigen Specific Lymphocytes and Monocytes After Immunization With the 17D Yellow Fever Vaccine

  Not yet reported Sri Edupuganti 27 participants Est. completion 2024-10-25 1 site Stand-alone
  Other conditions: Yellow Fever
  View official trial listing →
• Completed NCT NCT01348061

  Evaluating Cerebrospinal Fluid Biomarkers in Alzheimer's, Progressive Supranuclear Palsy Subjects, and Controls

  KineMed 16 participants Est. completion 2013-07 3 sites
  Other conditions: Alzheimer Disease, Progressive Supranuclear Palsy
  View official trial listing →
• Completed NCT NCT01544868

  Total Energy Expenditure, Protein Kinetics, and Body Composition in Recovering Burn Children.

  Not yet reported Shriners Hospitals for Children 12 participants Est. completion 2013-01 1 site
  Other conditions: Energy Expenditure in Burn Children, Protein Turnover in Burn Children
  View official trial listing →
• Completed NCT NCT01708525

  Feasibility Study: Heavy Water Tissue Labeling Protocol

  Not yet reported Ulthera, Inc 2 participants Est. completion 2013-11 1 site Stand-alone
  Other conditions: Skin Laxity
  View official trial listing →
• Completed NCT NCT01752426

  Pilot Study to Determine Effects of the Btk Inhibitor PCI-32765 on Leukemia Cell Kinetics and Trafficking, Using Heavy Water Labeling in Subjects With CLL and SLL

  Not yet reported, Not yet reported M.D. Anderson Cancer Center 30 participants Est. completion 2018-08-09 1 site Stand-alone
  Other conditions: Leukemia
  View official trial listing →
• Completed NCT NCT01962454

  A Study to Evaluate a Skeletal-muscle Microbiopsy Technique With Dynamic Proteomic Measurement in Healthy Male Volunteers

  Not yet reported GlaxoSmithKline 20 participants Est. completion 2015-03-20 1 site Stand-alone
  Other conditions: Cachexia
  View official trial listing →
• Terminated NCT NCT01978301

  Study to Evaluate Fractional Collagen Synthesis Within Keloid Scars and Identify Biomarkers of Keloid Scars

  Not yet reported GlaxoSmithKline 9 participants Est. completion 2015-02-05 1 site
  Other conditions: Fibrosis
  View official trial listing →
• Completed NCT NCT02118675

  Tanita BIA System Validation

  Pennington Biomedical Research Center 150 participants Est. completion 2015-12 1 site
  Other conditions: Body Composition, Circumference Measurements, Tissue Thickness Measurements
  View official trial listing →
• Completed NCT NCT02152839

  The Implementation of Novel 'Heavy' Water Techniques for Determining Modulation of Muscle Protein, DNA and Lipid Synthesis Due to Ageing

  Not yet reported University of Nottingham 20 participants 1 site
  Other conditions: Healthy
  View official trial listing →
• Completed NCT NCT02394470

  BioImpedentiometry, Lung UltraSound and cONgestion in Heart Failure

  Not yet reported Niguarda Hospital 60 participants Est. completion 2020-04 1 site
  Heart failure
  View official trial listing →
• Status unknown NCT NCT02505438

  Application of Deuterated Water (D2O) to Define the Etiology of Musculoskeletal Decline in Ageing and the Efficacy of Nutritional Supplementation

  Not yet reported University of Nottingham 48 participants 1 site
  Other conditions: Healthy
  View official trial listing →
• Completed NCT NCT02596776

  Cold Induced Changes in White Adipose

  Not yet reported Philip Kern 26 participants Est. completion 2018-08-20 1 site
  PrediabetesMetabolic syndrome Other conditions: Obese, Normal Body Weight
  View official trial listing →
• Completed NCT NCT03191513

  The Acute Effects of Interesterification of Commercially Used Fats on Postprandial Fat Metabolism

  Not yet reported King's College London 24 participants Est. completion 2018-05-27 1 site Stand-alone
  Other conditions: Healthy Adults, Postmenopausal Women
  View official trial listing →
• Completed NCT NCT03371680

  Kinetics of Surfactant Proteins, Phosphatidylcholine and Body Water in Intensive Care Unit (ICU)

  Not yet reported University of Padova 21 participants Est. completion 2013-12-31 Stand-alone
  Other conditions: ARDS, Sepsis Syndrome
  View official trial listing →
• Completed NCT NCT03447574

  Fluid Volume During Fluid Shifts

  Not yet reported Mayo Clinic 14 participants Est. completion 2022-10-26 3 sites
  Other conditions: Development of Non-invasive Protocol
  View official trial listing →
• Completed NCT NCT03683589

  De Novo Lipogenesis in Severity of NAFLD

  University of Missouri-Columbia 49 participants Est. completion 2020-07-31 1 site
  MASLDMASH Other conditions: Bariatric Surgery Candidate, Obesity, Morbid
  View official trial listing →
• Terminated NCT NCT04004325

  A Study of FT 4101 in Overweight/Obese Participants With Non-alcoholic Steatohepatitis

  Not yet reported, Not yet reported Forma Therapeutics, Inc. 14 participants Est. completion 2020-01-20 2 sites Stand-alone
  MASH Other conditions: Overweight or Obesity
  View official trial listing →
• Completed NCT NCT04020640

  Infant Feeding Practices in Transition: Breast Milk Intake, Complementary Feeding and Body Composition During Infancy

  Mahidol University 110 participants Est. completion 2016-11-22
  Other conditions: Breast Feeding
  View official trial listing →
• Completed NCT NCT04114383

  Concurrent Assessment of Skeletal Muscle Mass and Synthesis/Breakdown in Old Age

  University of Nottingham 37 participants Est. completion 2020-02 1 site
  Other conditions: Sarcopenia, Muscle Atrophy
  View official trial listing →
• Enrolling by invitation NCT NCT04209816

  Genetic Pathways Leading to Fatty Liver and Atherogenic Dyslipidemia

  Marja-Riitta Taskinen 100 participants Est. completion 2028-12 2 sites
  Other conditions: Non-alcoholic Fatty Liver, Atherogenic Dyslipidemia, Insulin Resistance
  View official trial listing →
• Withdrawn NCT NCT04256343

  D2O Dosing Strategies to Assess Muscle Protein Synthesis

  Not yet reported McMaster University Est. completion 2021-06-01
  Other conditions: Hypertrophy
  View official trial listing →
• Completed NCT NCT04325178

  Mycoprotein as the Basis of a Sustainable Diet to Support Muscle Mass Maintenance and Reconditioning in Older Adults.

  Not yet reported University of Exeter 19 participants Est. completion 2020-01-31 1 site
  Other conditions: Aging, Sarcopenia
  View official trial listing →
• Completed NCT NCT04332289

  Assessing Insulin Turnover Using an In-vivo Deuterated Water Experiment.

  Lia Bally 4 participants Est. completion 2020-08-20 1 site
  Other conditions: Bariatric Surgery, Hypoglycemia, Gastric Bypass
  View official trial listing →
• Completed NCT NCT04520477

  Watershift - Pilot Study

  Not yet reported University Hospital, Ghent 19 participants Est. completion 2019-07-01 1 site
  Other conditions: Total Body Water, Nocturnal Polyuria
  View official trial listing →
• Active, not recruiting NCT NCT04641026

  Discovery of Biological Signatures for Cruciferous Vegetable Intake (Single Serving)

  Not yet reported Oregon State University 83 participants Est. completion 2027-12 1 site
  Other conditions: Diet, Healthy
  View official trial listing →
• Status unknown NCT NCT04700475

  Effect of Low Level Laser Therapy on Prevention of Radiotherapy Induced Xerostomia in Cancer Patients.

  Not yet reported Nada Yousef 60 participants Est. completion 2021-02 1 site
  Other conditions: Head and Neck Cancer
  View official trial listing →
• Active, not recruiting NCT NCT04829110

  Alcohol Induced de Novo Lipogenesis in Women

  Not yet reported University of Texas Southwestern Medical Center 27 participants Est. completion 2027-03-31 1 site Stand-alone
  Other conditions: Liver Metabolism
  View official trial listing →
• Completed NCT NCT05020808

  The Effect of a Plant Protein Isolate on Muscle Protein Synthesis in Humans at Rest and After Resistance Exercise

  Not yet reported University of Limerick 33 participants Est. completion 2022-06-20 1 site
  Other conditions: Metabolism, Exercise, Dietary Supplements
  View official trial listing →
• Completed NCT NCT05111392

  Hydration Dynamics and Influence of Beverage Composition

  Not yet reported, Not yet reported University of Illinois at Chicago 14 participants Est. completion 2022-11-30 1 site
  Other conditions: Hydration, Fluid Retention, Dehydration
  View official trial listing →
• Status unknown NCT NCT05430178

  Metabolic Pathology of Pediatric NAFLD

  Not yet reported University of Oklahoma 100 participants Est. completion 2026-06 1 site Stand-alone
  MASH Other conditions: Nonalcoholic Fatty Liver, Obesity
  View official trial listing →
• Completed NCT NCT05482243

  Protein and Exercise Training in Chronic KIDNEY Disease

  Not yet reported Maastricht University Medical Center 40 participants Est. completion 2024-12-02 1 site Stand-alone
  Other conditions: Kidney Diseases, Muscle Loss
  View official trial listing →
• Completed NCT NCT05729282

  Glycemic Effect of Diazoxide in NAFLD

  Not yet reported Columbia University 22 participants Est. completion 2025-09-10 1 site Stand-alone
  Other conditions: Hyperinsulinemia, Insulin Resistance, Non-Alcoholic Fatty Liver Disease, Prediabetic State
  View official trial listing →
• Completed NCT NCT05959460

  Assessing Exclusive Breastfeeding Practice

  Mahidol University 206 participants Est. completion 2020-01-01
  Other conditions: Exclusive Breastfeeding, Human Milk, Breast Milk
  View official trial listing →
• Completed NCT NCT06002620

  Healthynsect Child Growth and Health Intervention Study

  Not yet reported University of Copenhagen 284 participants Est. completion 2024-01-16 1 site
  Other conditions: Nutrition Status
  View official trial listing →
• Status unknown NCT NCT06063005

  Clinical Study of Translocated Internal Limiting Membrane Flap Reposition for the Treatment of Idiopathic Macular Hole

  Not yet reported Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 76 participants Est. completion 2025-06-30 1 site Stand-alone
  Other conditions: Macular Holes
  View official trial listing →
• Active, not recruiting NCT NCT06100913

  Immunology of Ebola Vaccine

  Not yet reported Emory University 30 participants Est. completion 2027-08-31 2 sites
  Other conditions: Ebola Virus Disease
  View official trial listing →
• Completed NCT NCT06553794

  Protein Digestion and Amino Acid Absorption in the Aging Gastrointestinal Tract

  Not yet reported Maastricht University Medical Center 24 participants Est. completion 2025-06-13 1 site Stand-alone
  Other conditions: Protein Malabsorption
  View official trial listing →
• Enrolling by invitation NCT NCT06942312

  Elucidating Hepatic Metabolism in Non-alcoholic Fatty Liver Disease

  Helsinki University Central Hospital 30 participants Est. completion 2030-12-31 1 site
  MASLD
  View official trial listing →
• Not yet recruiting NCT NCT07048080

  Prehabilitation in Older People Undergoing Total Hip Replacement

  Not yet reported Universidad de La Frontera 70 participants Est. completion 2029-03 1 site Stand-alone
  Osteoarthritis
  View official trial listing →
• Active, not recruiting NCT NCT07055269

  Liver Metabolic Functions in Patients With Citrin Deficiency and Healthy Subjects

  Not yet reported Johannes Haeberle 20 participants Est. completion 2026-09 1 site Stand-alone
  Other conditions: Citrin Deficiency
  View official trial listing →
• Completed NCT NCT07119749

  Vegan Whey Protein for Muscle Anabolism and Post-exercise Recovery

  Not yet reported University of Birmingham 27 participants Est. completion 2024-11-22 1 site
  Other conditions: Muscle Soreness
  View official trial listing →
• Not yet recruiting NCT NCT07389837

  Maple Syrup Carbohydrate Dose-Response on 20-km Cycling Time-Trial Performance

  Not yet reported Université de Montréal 32 participants Est. completion 2027-06-01 1 site
  Other conditions: Exercise, Endurance Cycling Performance, Carbohydrate Intolerance, Sport Nutrition
  View official trial listing →
• Active, not recruiting NCT NCT07502755

  Non-invasive Tests for Non-alcoholic Steato-hepatitis

  Not yet reported Fondazione Policlinico Universitario Agostino Gemelli IRCCS 828 participants Est. completion 2027-02-28 1 site Stand-alone
  MASH Other conditions: Diabete Type 2, Obesity
  View official trial listing →
• Completed NCT NCT07742423

  Implementation and Validation of an Analytical Protocol for Measuring de Novo Lipogenesis in the Liver Using Stable Isotopes

  Not yet reported KU Leuven 10 participants Est. completion 2025-12-11 1 site
  Other conditions: De Novo Lipogenesis (DNL), Lipid Metabolism, Stable Isotope Tracing, Healthy Volunteers (HV)
  View official trial listing →

Not yet reported.

Not yet reported.

• ClinicalTrials.gov — NCT05729282

Also known as: Deuterated water, Deuterated water (2H2O/D2O), Heavy water

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