About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Coagadex
- Company
- Kedrion S.p.A.
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 4 recruiting
Efficacy results: Not yet reported
4 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Nov 6, 2026
Find a Clinical Trial Near Me
See recruiting studies for Coagadex and check eligibility with the study team.
Trial details
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Recruiting NCT NCT04023019
Treatment of Hemophilia A Patients With FVIII Inhibitors
Emory University 120 participants Est. completion 2029-06 2 sitesOther conditions: Hemophilia AView official trial listing → -
Recruiting NCT NCT04563520
SAFE Study: Safety of aPCC Following Emicizumab Prophylaxis
Not yet reported Emory University 5 participants Est. completion 2027-03 2 sitesOther conditions: Hemophilia AView official trial listing → -
Recruiting NCT NCT04567511
Hemlibra in Mild Hemophilia A
Not yet reported Indiana Hemophilia &Thrombosis Center, Inc. 20 participants Est. completion 2027-07 1 siteOther conditions: Factor VIII Deficiency, CongenitalView official trial listing → -
Recruiting NCT NCT07875478
A Database For The Collection Of Clinical, Laboratory, And Treatment Data From Patients With Factor X Deficiency To Define The Natural History Of The Disease And Improve Patient Management
Fondazione Luigi Villa 20 participants Est. completion 2029-06-14 2 sitesOther conditions: Factor X DeficiencyView official trial listing → -
Status unknown NCT NCT00257179
The Serum Tissue Factor Level in Lung Cancer Patients as a Prognostic Factor
National Taiwan University Hospital 200 participants 1 siteOther conditions: Lung CancerView official trial listing → -
Status unknown NCT NCT00458666
Coagulation Parameters During Pregnancy in Amniotic Fluid
Rambam Health Care Campus 170 participants 1 siteOther conditions: PregnancyView official trial listing → -
Completed NCT NCT00930176
A Study Investigating Treatment Factor X in People With Factor X Deficiency
Not yet reported Bio Products Laboratory 16 participants Est. completion 2013-11 14 sitesOther conditions: Factor X DeficiencyView official trial listing → -
Completed NCT NCT00970619
DUTCH CAVA-trial: CAtheter Versus Anticoagulation Alone for Acute Primary (Ilio)Femoral DVT.
Not yet reported Maastricht University Medical Center 184 participants Est. completion 2018-11 16 sitesOther conditions: Acute Thrombosis of Deep Veins of Proximal Lower ExtremityView official trial listing → -
Completed NCT NCT00986635
Effect of Rivaroxaban on Coagulation Parameters- an ex Vivo Study
Johann Wolfgang Goethe University Hospital 100 participants Est. completion 2011-04 1 siteOther conditions: Differences in Laboratory Coagulation ParametersView official trial listing → -
Terminated NCT NCT01086852
Safety & Efficacy of BPL's High Purity FACTOR X in Treatment of Factor X Deficient Subjects Undergoing Surgery
Not yet reported Bio Products Laboratory 4 participants Est. completion 2014-01 7 sitesOther conditions: Factor X DeficiencyView official trial listing → -
Completed NCT NCT01352143
Thrombin Generation in Neonatal Plasma After Cardiopulmonary Bypass
Emory University 24 participants Est. completion 2012-06 1 siteOther conditions: Cardiopulmonary BypassView official trial listing → -
Completed NCT NCT01656330
A Study to Assess the Effects of 2 Different Prothrombin Complex Concentrates on the Pharmacodynamics of Rivaroxaban in Healthy Adult Volunteers
Not yet reported Janssen Research & Development, LLC 35 participants Est. completion 2012-08 1 siteOther conditions: HealthyView official trial listing → -
Completed NCT NCT01660061
Monitoring Anticoagulant Therapy in Antiphospholipid Syndrome
Johann Wolfgang Goethe University Hospital 150 participants Est. completion 2014-12 1 siteOther conditions: Antiphospholipid SyndromeView official trial listing → -
Completed NCT NCT01687491
Comparison of Anti-Xa Activity of ENOXA ® Versus LOVENOX ® in Acute Coronary Syndrome
Not yet reported Les Laboratoires des Médicaments Stériles 179 participants Est. completion 2014-10 1 siteOther conditions: Acute Coronary Syndrome, Factor XView official trial listing → -
Completed NCT NCT01721681
A Study to Investigate Bio Product Laboratory Ltd (BPL's) Factor X in the Prophylaxis of Bleeding in Children <12 Years
Not yet reported Bio Products Laboratory 9 participants Est. completion 2016-10 3 sitesOther conditions: Factor X DeficiencyView official trial listing → -
Completed NCT NCT02047565
A Two-part Study in Edoxaban-treated Healthy Subjects to Establish a Punch Biopsy Bleeding Model and to Evaluate the Effect of a 4-factor Prothrombin Complex Concentrate on Anticoagulation
Not yet reported Daiichi Sankyo 110 participants Est. completion 2014-05 1 siteOther conditions: BleedingView official trial listing → -
Completed NCT NCT02074358
A Study to Assess the Effects of 2 Prothrombin Complex Concentrates on the Pharmacodynamics of Apixaban in Healthy Adult Subjects
Not yet reported Bristol-Myers Squibb 43 participants Est. completion 2014-04Other conditions: AnticoagulationView official trial listing → -
Completed NCT NCT02099318
Surgical Theater's Surgery Rehearsal Platform
Not yet reported University Hospitals Cleveland Medical Center 40 participants Est. completion 2015-09 1 siteOther conditions: Cerebral Aneurysm Unruptured, Cerebral Aneurysm RupturedView official trial listing → -
Completed NCT NCT02319460
An Observational Cohort Study to Investigate the Risk of Thromboembolic Events in Patients Receiving Kcentra® or Plasma to Reverse Vitamin K Antagonist (VKA) Therapy in the Setting of Acute Major Bleeding
CSL Behring 2238 participants Est. completion 2020-06-30 1 siteOther conditions: HemorrhageView official trial listing → -
Status unknown NCT NCT02463591
Reversal of Dabigatran With Prothrombin Complex Concentrate
Not yet reported University Medical Center Groningen 12 participants Est. completion 2016-12 1 siteOther conditions: Drug Action ReversalView official trial listing → -
Completed NCT NCT02740335
Study of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk.
Not yet reported Octapharma 208 participants Est. completion 2022-02-23 86 sitesOther conditions: Significant Bleeding RiskView official trial listing → -
Completed NCT NCT02914353
Study to Evaluate Safety, PK and PD of Single and Multiple Ascending Doses of EP-7041 in Healthy Subjects
Not yet reported eXIthera Pharmaceuticals 80 participants Est. completion 2017-05 1 siteOther conditions: Arthroplasty, Replacement, KneeView official trial listing → -
Completed NCT NCT03161626
Registry Study of COAGADEX® Patients With Moderate or Severe Hereditary Factor X Deficiency Undergoing Major Surgery
Bio Products Laboratory 3 participants Est. completion 2021-10-13 3 sitesOther conditions: Factor 10 DeficiencyView official trial listing → -
Completed NCT NCT03270865
Usability and Ergonomic Evaluation of Self-Positioning System for Retinal Imaging
Not yet reported Notal Vision Ltd. 16 participants Est. completion 2018-09-30 1 siteOther conditions: AMD Population - Intermediate or Advanced AMD, DR Population- With or Without Diabetic Macular EdemaView official trial listing → -
Status unknown NCT NCT03287999
Inter Individual Variability in Initiation Pathway Activation and Regulation and Phenotypic Heterogeneity in Patients With Haemophilia A and B
Royal Free Hospital NHS Foundation Trust 250 participants Est. completion 2020-10-02 1 siteOther conditions: HaemophiliaView official trial listing → -
Status unknown NCT NCT03347591
Rare Bleeding Disorders in the Netherlands
Radboud University Medical Center 300 participants Est. completion 2022-01-01 7 sitesOther conditions: Rare Bleeding DisordersView official trial listing → -
Terminated NCT NCT03921294
HemLibra Prophylaxis in Patients With Hemophilic Pseudotumor
Not yet reported Indiana Hemophilia &Thrombosis Center, Inc. 1 participants Est. completion 2022-03-16 1 siteOther conditions: Haemophilic PseudotumourView official trial listing → -
Terminated NCT NCT04233073
Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery
Not yet reported Alexion Pharmaceuticals, Inc. 10 participants Est. completion 2022-01-25 56 sitesOther conditions: SurgeryView official trial listing → -
Terminated NCT NCT04244981
Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery
Not yet reported SHI Jia 476 participants Est. completion 2025-04-09 2 sitesOther conditions: Valvular Heart SurgeryView official trial listing → -
Completed NCT NCT04372173
An Evaluation of Clotting Factor Activity Before and After Total Hip Arthroplasty
Military Institute od Medicine National Research Institute 30 participants Est. completion 2020-01-31 1 siteOther conditions: Arthroplasty, Replacement, Coagulation FactorsView official trial listing → -
Status unknown NCT NCT04539301
Multicentric Prospective Validation of a Universal Test to Quantify Apixaban, Rivaroxaban, Danaparoid and Fondaparinux Levels
Nantes University Hospital 2100 participants Est. completion 2024-05-01 1 siteOther conditions: Anticoagulation, Venous Thromboembolism, Atrial FibrillationView official trial listing → -
Completed NCT NCT04569279
Rivaroxaban vs. Warfarin in CVT Treatment
Not yet reported Damascus University 71 participants Est. completion 2020-03-01 1 siteOther conditions: Cerebral Vein ThrombosisView official trial listing → -
Completed NCT NCT05012501
Analysis of Neutrophil Extracellular Traps in Hypercoagulability and Portal Vein Thrombosis in Liver Cirrhosis Patients
The Affiliated Hospital of Qingdao University 79 participants Est. completion 2021-02-28 1 siteOther conditions: Neutrophil Extracellular Trap Formation, Portal Vein Thrombosis, Liver CirrhosisView official trial listing → -
Completed NCT NCT05152420
Study of Intravenous VMX-C001 in Healthy Subjects and in Combination With Selected Direct Oral Anticoagulants in Healthy Older Subjects
Not yet reported VarmX B.V. 105 participants Est. completion 2023-02-03 1 siteOther conditions: Coagulation DisorderView official trial listing → -
Completed NCT NCT05226442
Safety and Feasibility of Argatroban As Anticoagulant in Adults with ECMO
Not yet reported, Not yet reported Medical University of Vienna 40 participants Est. completion 2024-07-07 1 siteOther conditions: Extracorporeal Membrane Oxygenation Complication, Anticoagulants and Bleeding DisordersView official trial listing → -
Terminated NCT NCT05568888
Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study )
Not yet reported CSL Behring 1366 participants Est. completion 2024-10-29 113 sitesOther conditions: Traumatic InjuryView official trial listing → -
Completed NCT NCT06372483
Single Dose Trial of VMX-C001 in Healthy Subjects With and Without FXa Direct Oral Anticoagulant
Not yet reported VarmX B.V. 40 participants Est. completion 2026-08-26 1 siteOther conditions: Coagulation DisorderView official trial listing → -
Completed NCT NCT06517563
Effects of VMX-C001 on the Anticoagulant Effect of Different Forms of Heparin
Not yet reported VarmX B.V. 16 participants Est. completion 2026-04-13 1 siteOther conditions: Coagulation DisorderView official trial listing → -
Terminated NCT NCT06929260
A Study to Evaluate the Effect of Ceralasertib on Drug X, Drug Y and Drug Z
Not yet reported AstraZeneca 1 participants Est. completion 2025-12-18 1 siteOther conditions: Advanced Solid TumoursView official trial listing → -
Withdrawn NCT NCT06963216
A Study Investigating Coagadex in the Treatment AFXD Associated With AL Amyloidosis
Not yet reported Kedrion S.p.A. Est. completion 2026-06-10 Stand-aloneOther conditions: Acquired Factor X DeficiencyView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Coagadex, Coagadex(R)
Related On The Pen coverage
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
