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Recruiting
NCT NCT07227922
Clofutriben Pharmacokinetics in Patients With Impaired Renal Function
Not yet reported
Sparrow Pharmaceuticals
16 participants
Est. completion 2026-07-01
1 site
Stand-alone
Other conditions: Moderate Renal Impairment
View official trial listing →
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Recruiting
NCT NCT07296484
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
Not yet reported
Sparrow Pharmaceuticals
1500 participants
Est. completion 2028-06-30
61 sites
Stand-alone
Type 2 diabetes
Other conditions: Cortisol Excess
View official trial listing →
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Completed
NCT NCT02194491
A Positron Emission Tomography Occupancy Study Using Ligand [11C]AS2471907 and Following Oral Dosing of ASP3662
Not yet reported
Astellas Pharma Global Development, Inc.
18 participants
Est. completion 2016-05
1 site
Stand-alone
Other conditions: Pharmacokinetics of ASP3662, Displacement of Radiotracer, Healthy Volunteers
View official trial listing →
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Terminated
NCT NCT02372578
Study to Assess Analgesic Efficacy and Safety of ASP3662 in Subjects With Painful Diabetic Peripheral Neuropathy
Not yet reported
Astellas Pharma Global Development, Inc.
115 participants
Est. completion 2016-05-20
37 sites
Stand-alone
Other conditions: Painful Diabetic Peripheral Neuropathy (PDPN)
View official trial listing →
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Completed
NCT NCT05307328
SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome
Not yet reported
Sparrow Pharmaceuticals
26 participants
Est. completion 2025-08-01
12 sites
Stand-alone
Other conditions: Cushing's Syndrome I, Cushing Disease Due to Increased ACTH Secretion, Cortisol Excess, Cortisol; Hypersecretion, Cortisol Overproduction, Ectopic ACTH Secretion
View official trial listing →
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Completed
NCT NCT05409027
A Study to Assess 11 Beta-hydroxysteroid Dehydrogenase Type 1 Inhibition in Adipose Tissue by SPI-62
Not yet reported
Sparrow Pharmaceuticals
12 participants
Est. completion 2024-02-07
1 site
Stand-alone
Type 2 diabetes
Other conditions: Obesity, Type2Diabetes
View official trial listing →
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Completed
NCT NCT05436639
SPI-62 as a Treatment for Hypercortisolism Related to a Benign Adrenal Tumor
Not yet reported
Sparrow Pharmaceuticals
30 participants
Est. completion 2025-02-18
5 sites
Stand-alone
Other conditions: Autonomous Cortisol Secretion (ACS), ACTH-Independent Cushing Syndrome, ACTH-Independent Adrenal Cushing Syndrome, Somatic
View official trial listing →
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Completed
NCT NCT05436652
A Trial of Prednisolone in Combination With SPI-62 or Placebo in Subjects With Polymyalgia Rheumatica (PMR)
Not yet reported
Sparrow Pharmaceuticals
66 participants
Est. completion 2025-04-25
10 sites
Stand-alone
Other conditions: Polymyalgia Rheumatica
View official trial listing →
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Terminated
NCT NCT06281236
A Trial of Prednisolone in Combination With SPI-62 in Participants With Polymyalgia Rheumatica (PMR)
Not yet reported
Sparrow Pharmaceuticals
1 participants
Est. completion 2025-04-25
5 sites
Stand-alone
Other conditions: Polymyalgia Rheumatica
View official trial listing →
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Completed
NCT NCT07226635
Pharmacokinetic Interaction Trial of Clofutriben With Midazolam and Prednisolone
Not yet reported
Sparrow Pharmaceuticals
16 participants
Est. completion 2025-12-16
1 site
Stand-alone
Other conditions: Healthy Participants
View official trial listing →