Chlorthalidone with potassium chloride

• Recruiting NCT NCT05293756

  OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)

  Not yet reported Case Western Reserve University 208 participants Est. completion 2027-05-31 1 site
  Other conditions: Hypertension, Self-Management, Technology, Quality of Life
  View official trial listing →
• Recruiting NCT NCT05593055

  Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

  Not yet reported Brigham and Women's Hospital 75 participants Est. completion 2027-12-31 1 site
  Other conditions: Hypertension, Left Ventricular Hypertrophy
  View official trial listing →
• Recruiting NCT NCT06111885

  Indapamide and Chlorthalidone to Reduce Urine Supersaturation for Kidney Stone Prevention

  Not yet reported Insel Gruppe AG, University Hospital Bern 99 participants Est. completion 2027-06-30 1 site
  Other conditions: Kidney Stone
  View official trial listing →
• Recruiting NCT NCT06495710

  Arterial Stiffness and Blood Pressure

  Not yet reported VA Office of Research and Development 228 participants Est. completion 2028-12-31 3 sites
  Other conditions: Hypertension, Vascular Stiffness, Aging
  View official trial listing →
• Recruiting NCT NCT07225764

  CaOx Stone Prevention

  Not yet reported Icahn School of Medicine at Mount Sinai 80 participants Est. completion 2027-12-31 1 site
  Other conditions: Kidney Stones
  View official trial listing →
• Recruiting NCT NCT07238400

  Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia

  Not yet reported Massachusetts General Hospital 90 participants Est. completion 2029-03-30 2 sites
  Other conditions: Hypertension
  View official trial listing →
• Recruiting NCT NCT07784296

  Effectiveness and Safety of Sequential Triple Combination Therapy (Amlodipine/Losartan/Chlorthalidone) in Korean Patients With Hypertension

  Hanmi Pharmaceutical Company Limited 3500 participants Est. completion 2028-08-31 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT00000499

  Systolic Hypertension in the Elderly Program (SHEP) (Pilot Study)

  Not yet reported National Heart, Lung, and Blood Institute (NHLBI) Est. completion 1983-05
  Cardiovascular disease Other conditions: Heart Diseases, Hypertension, Vascular Diseases
  View official trial listing →
• Completed NCT NCT00000513

  Trial of Antihypertensive Intervention Management

  Not yet reported National Heart, Lung, and Blood Institute (NHLBI) Est. completion 1994-11
  Cardiovascular disease Other conditions: Heart Diseases, Hypertension, Vascular Diseases
  View official trial listing →
• Completed NCT NCT00000514

  Systolic Hypertension in the Elderly Program (SHEP)

  Not yet reported National Heart, Lung, and Blood Institute (NHLBI) Est. completion 1996-10
  Cardiovascular disease Other conditions: Cerebrovascular Disorders, Heart Diseases, Hypertension
  View official trial listing →
• Completed NCT NCT00000522

  Treatment of Mild Hypertension Study (TOMHS)

  Not yet reported University of Minnesota Est. completion 1994-05
  Cardiovascular disease Other conditions: Heart Diseases, Hypertension, Vascular Diseases
  View official trial listing →
• Completed NCT NCT00000525

  Diuretics, Hypertension, and Arrhythmias Clinical Trial

  Not yet reported University of California, San Francisco 233 participants
  Cardiovascular diseaseSubstance use disorder Other conditions: Heart Arrest, Heart Diseases, Hypertension
  View official trial listing →
• Completed NCT NCT00000542

  Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

  Not yet reported National Heart, Lung, and Blood Institute (NHLBI) Est. completion 2002-03
  Cardiovascular diseaseHeart failure Other conditions: Coronary Disease, Diabetes Mellitus, Heart Diseases, Hypercholesterolemia, Hypertension, Myocardial Ischemia
  View official trial listing →
• Completed NCT NCT00000620

  Action to Control Cardiovascular Risk in Diabetes (ACCORD)

  Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 10251 participants Est. completion 2012-12 7 sites
  Cardiovascular diseaseType 2 diabetes Other conditions: Atherosclerosis, Hypercholesterolemia, Hypertension, Diabetes Mellitus, Coronary Disease
  View official trial listing →
• Completed NCT NCT00006294

  Genetics of Hypertension Associated Treatments (GenHAT)

  Donna Arnett, 257-5678 37939 participants Est. completion 2005-08 1 site
  Cardiovascular disease Other conditions: Heart Diseases, Hypertension, Coronary Disease
  View official trial listing →
• Completed NCT NCT00007592

  Hypertension Screening and Treatment Program

  US Department of Veterans Affairs 12 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT00231803

  The Canadian Prevention of Renal and Cardiovascular Endpoints Trial

  Not yet reported Brendan Barrett 474 participants Est. completion 2008-06 5 sites
  Chronic kidney disease
  View official trial listing →
• Completed NCT NCT00241839

  Uric Acid and Hypertension in African Americans

  Not yet reported University of Florida 150 participants Est. completion 2011-05 1 site
  Cardiovascular disease Other conditions: Heart Diseases, Hypertension
  View official trial listing →
• Completed NCT NCT00353652

  Effects of Thiazide Diuretics on Sympathetic Nervous System in Hypertension

  Not yet reported University of Texas Southwestern Medical Center 166 participants Est. completion 2013-01 2 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT00563901

  Analyzing How Genetics May Affect Response to High Blood Pressure Medications

  University of Alabama at Birmingham 37939 participants Est. completion 2004-05 2 sites
  Other conditions: Hypertension, Coronary Disease, Cerebrovascular Accident
  View official trial listing →
• Completed NCT NCT00591773

  Efficacy and Safety of Azilsartan Medoxomil Co-Administered With Chlorthalidone in Participants With Essential Hypertension

  Not yet reported Takeda 551 participants Est. completion 2009-03 46 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT00670787

  Combination Pill of Losartan Potassium and Hydrochlorothiazide for Improvement of Medication Compliance Trial

  Not yet reported Kyushu University 207 participants Est. completion 2011-02 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT00684489

  Renin-Guided Therapeutics in the Management of Untreated, Uncontrolled, or Complicated Hypertension

  Not yet reported Medical University of South Carolina 52 participants Est. completion 2005-09
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT00695955

  One-Year Safety and Tolerability Study of Azilsartan Medoxomil in Participants With Essential Hypertension

  Not yet reported Takeda 669 participants Est. completion 2010-05 41 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT00696384

  A Safety and Tolerability Study of Azilsartan Medoxomil in Participants With Essential Hypertension

  Not yet reported Takeda 418 participants Est. completion 2009-04 45 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT00818883

  Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone in Participants With Moderate to Severe Hypertension

  Not yet reported Takeda 609 participants Est. completion 2009-11 53 sites
  Other conditions: Essential Hypertension
  View official trial listing →
• Completed NCT NCT00846365

  Efficacy and Safety of Azilsartan Medoxomil Plus Chlorthalidone in Participants With Moderate to Severe Hypertension

  Not yet reported Takeda 1085 participants Est. completion 2010-06 80 sites
  Other conditions: Essential Hypertension
  View official trial listing →
• Completed NCT NCT00847626

  Efficacy and Safety of Azilsartan Medoxomil Combined With Chlorthalidone in Participants With Moderate to Severe Hypertension

  Not yet reported Takeda 1711 participants Est. completion 2010-07 99 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT00970931

  Hypertension Prevention in Pre-Hypertensive Individuals

  Not yet reported Hospital de Clinicas de Porto Alegre 730 participants Est. completion 2014-09 2 sites
  Cardiovascular disease Other conditions: Pre-hypertension, Hypertension
  View official trial listing →
• Completed NCT NCT00971165

  Diuretics and Angiotensin-Receptor Blocker Agents in Patients With Stage I Hypertension

  Not yet reported Hospital de Clinicas de Porto Alegre 655 participants Est. completion 2014-09 2 sites
  Cardiovascular disease Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT00996281

  Safety and Tolerability of Azilsartan Medoxomil Plus Chlorthalidone Compared to Olmesartan Medoxomil Plus Hydrochlorothiazide in Participants With Essential Hypertension

  Not yet reported Takeda 837 participants Est. completion 2011-11 26 sites
  Other conditions: Essential Hypertension
  View official trial listing →
• Completed NCT NCT01033071

  Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Moderate to Severe Hypertension.

  Not yet reported Takeda 1071 participants Est. completion 2010-11 94 sites
  Other conditions: Essential Hypertension
  View official trial listing →
• Completed NCT NCT01083017

  Resistant Arterial Hypertension Cohort Study

  University Hospital, Geneva 74 participants Est. completion 2017-05 3 sites
  Other conditions: Hypertension, Essential Hypertension, Resistant Hypertension
  View official trial listing →
• Completed NCT NCT01191450

  Safety and Efficacy of Chlorthalidone + Amiloride to Elderly Patients Treatment With Arterial Hypertension

  Not yet reported Eurofarma Laboratorios S.A. 246 participants Est. completion 2013-08 10 sites
  Other conditions: Arterial Hypertension
  View official trial listing →
• Completed NCT NCT01203852

  Pharmacogenomic Evaluation of Antihypertensive Responses 2

  Not yet reported University of Florida 839 participants Est. completion 2014-04 3 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT01235377

  Tolerance to Target Doses of Thiazides in Actual Practice: A Feasibility Study

  Not yet reported VA Pharmacy Benefits Management Strategic Healthcare Group 20 participants Est. completion 2014-02 5 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT01309828

  Long-Term Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Hypertension and Kidney Disease

  Not yet reported Takeda 153 participants Est. completion 2012-10 53 sites
  Other conditions: Safety
  View official trial listing →
• Terminated NCT NCT01368536

  Study to Evaluate the Efficacy and Safety of the Combination of Valturna and Amlodipine or Valturna and Chlorthalidone Versus Valturna Alone in Patients With Stage 2 Hypertension and Diabetes

  Not yet reported Novartis Pharmaceuticals 975 participants Est. completion 2012-02 97 sites
  Other conditions: Hypertension, Stage 2 Hypertension, Diabetes
  View official trial listing →
• Completed NCT NCT01456169

  A Study to Evaluate the Effectiveness and Safety of a Fixed Dose Combination of Azilsartan Medoxomil and Chlorthalidone in Patients With High Blood Pressure Who do Not Achieve Target Blood Pressure Following Treatment With Azilsartan Medoxomil Alone

  Not yet reported Takeda 507 participants Est. completion 2013-01 108 sites
  Other conditions: Essential Hypertension
  View official trial listing →
• Withdrawn NCT NCT01748123

  EBMtrialcentral- Comparing Initial Diuretic Therapies Using a Collaborative Network

  Not yet reported Johns Hopkins University Est. completion 2018-06 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT01750294

  A Pilot Study of Chlorthalidone Among Patients With Poorly Controlled Hypertension and CKD

  Not yet reported Indiana University 14 participants Est. completion 2013-08 1 site
  Chronic kidney disease Other conditions: Poorly-Controlled Hypertension
  View official trial listing →
• Completed NCT NCT01806363

  Pharmacokinetic Interactions and Safety Study of Telmisartan and Chlorthalidone

  Not yet reported HanAll BioPharma Co., Ltd. 60 participants Est. completion 2013-06 1 site
  Other conditions: Hypertension
  View official trial listing →
• Withdrawn NCT NCT01822860

  Chlorthalidone Compared to Hydrochlorothiazide on Endothelial Function

  Not yet reported Creighton University Est. completion 2015-02 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT01850160

  Efficacy/Safety Study of Valsartan and Chlorthalidone Conjugate Treatment Compared to Simple Treatment for Hypertension

  Not yet reported Farma de Colombia SA 124 participants Est. completion 2015-05 8 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT01896661

  Effect of Antihypertensive Agents Over Sleep Apnea

  Not yet reported Hospital de Clinicas de Porto Alegre 53 participants Est. completion 2016-02 1 site
  Obstructive sleep apnea Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT01973335

  Acetazolamide and Spironolactone to Increase Natriuresis in Congestive Heart Failure

  Not yet reported Hasselt University 34 participants Est. completion 2017-10 2 sites
  Heart failure
  View official trial listing →
• Withdrawn NCT NCT02030314

  The Management of Resistant Hypertension in Kidney Transplant Patients Using Chlorthalidone

  Not yet reported Virginia Commonwealth University Est. completion 2017-04-12 1 site
  Other conditions: Resistant Hypertension in Kidney Transplant Patients
  View official trial listing →
• Status unknown NCT NCT02100462

  Chlorthalidone and HCTZ Impacts on Platelet Activation

  Not yet reported Creighton University 30 participants Est. completion 2016-12 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT02121041

  Ambulatory vs Office BP Management Usual Care for Diagnosing and Managing Hypertension: A Pilot Study

  Not yet reported Anthony J Viera, MD, MPH 28 participants Est. completion 2016-07 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT02152969

  Drug-drug Interaction Study (Telmisartan, Amlodipine, Chlorthalidone)

  Not yet reported Yuhan Corporation 66 participants Est. completion 2014-11 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT02185417

  Diuretic Comparison Project

  Not yet reported VA Office of Research and Development 20723 participants Est. completion 2022-12-29 70 sites
  Other conditions: Hypertension
  View official trial listing →
• Terminated NCT NCT02232880

  Treatment of Resistant Hypertension by Prevention of T-Cell Co-Stimulation

  Not yet reported Vanderbilt University Medical Center 1 participants Est. completion 2015-06 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT02236520

  Tissue Sodium in Pre-hypertensive Patients

  Not yet reported Vanderbilt University 71 participants Est. completion 2018-05-01 1 site
  Other conditions: Hypertension
  View official trial listing →
• Withdrawn NCT NCT02357004

  Mechanisms of Refractory Hypertension (Carvedilol)

  Not yet reported University of Alabama at Birmingham Est. completion 2020-01-31
  Other conditions: Hypertensive
  View official trial listing →
• Completed NCT NCT02387554

  Pharmacokinetic Interaction Between HGP0904, HGP0608 and HGP1405

  Not yet reported Hanmi Pharmaceutical Company Limited 33 participants Est. completion 2014-10 1 site
  Other conditions: Hypertension(HTN)
  View official trial listing →
• Withdrawn NCT NCT02483936

  Efficacy and Safety of Olmesartan Associated With Chlorthalidone Versus Benicar HCT® in Essential Hypertension Control

  Not yet reported EMS
  Other conditions: Arterial Hypertension
  View official trial listing →
• Withdrawn NCT NCT02493322

  Efficacy and Safety of Olmesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control

  Not yet reported EMS
  Other conditions: Essential Arterial Hypertension
  View official trial listing →
• Completed NCT NCT02496910

  PK Study of YH22162 FDC Compared to Combination of Twynsta and Hygroton

  Not yet reported Yuhan Corporation 180 participants Est. completion 2015-09 1 site
  Other conditions: Hypertension
  View official trial listing →
• Status unknown NCT NCT02502981

  Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKD

  Not yet reported University Hospital Birmingham 154 participants Est. completion 2018-05 4 sites
  Other conditions: Renal Insufficiency, Chronic, Cardio-Renal Syndrome
  View official trial listing →
• Withdrawn NCT NCT02521233

  Efficacy and Safety of Candesartan Associated With Chlorthalidone in Essential Arterial Hypertension Control

  Not yet reported EMS Est. completion 2017-08
  Other conditions: Essential Arterial Hypertension
  View official trial listing →
• Withdrawn NCT NCT02521246

  Efficacy and Safety of Candesartan Associated With Chlorthalidone Versus Losartan Associated With Hydrochlorothiazide (Hyzaar®) in Essential Hypertension Control

  Not yet reported EMS Est. completion 2017-08
  Other conditions: Essential Arterial Hypertension
  View official trial listing →
• Completed NCT NCT02591628

  Treatment of Hypertension In Adults With ThiaZIDES: Pragmatic Trial Pilot Study

  Not yet reported HealthPartners Institute 2027 participants Est. completion 2017-07 2 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT02620163

  Efficacy & Safety Study of YH22162 vs Telmisartan/Amlodipine in Patients With Hypertension Inappropriately Controlled on Telmisartan/Amlodipine Treatment

  Not yet reported Yuhan Corporation 381 participants Est. completion 2016-12 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT02644395

  Thiazide Diuretics for Hypertension in Kidney Transplant Recipients Using Tacrolimus

  Not yet reported Erasmus Medical Center 49 participants Est. completion 2016-12-19 1 site
  Other conditions: Hypertension, Kidney Transplantation
  View official trial listing →
• Completed NCT NCT02665117

  Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate

  Not yet reported University of Texas Southwestern Medical Center 61 participants Est. completion 2022-11-04 3 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT02711670

  Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine Calcium

  Not yet reported VA New York Harbor Healthcare System 10 participants Est. completion 2017-06 1 site
  Other conditions: Kidney Stones
  View official trial listing →
• Completed NCT NCT02814552

  OPTImizing Precision of Hypertension Care to Maximize Blood Pressure Control Pilot (OPTI-BP Pilot)

  Not yet reported University of Florida 47 participants Est. completion 2018-06-30 3 sites
  Other conditions: High Blood Pressure
  View official trial listing →
• Completed NCT NCT02841280

  Chlorthalidone in Chronic Kidney Disease

  Not yet reported Indiana University 160 participants Est. completion 2021-04 1 site
  Other conditions: Renal Insufficiency, Chronic, Hypertension
  View official trial listing →
• Completed NCT NCT02847338

  Comparison of Optimal Hypertension Regimens

  Not yet reported Cambridge University Hospitals NHS Foundation Trust 940 participants Est. completion 2023-10 14 sites
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT02896621

  Effect of Antihypertensive Agents on Diastolic Function in Patients With Sleep Apnea

  Not yet reported Hospital de Clinicas de Porto Alegre 69 participants Est. completion 2017-02-14 1 site
  Other conditions: Hypertension, Sleep Apnea
  View official trial listing →
• Completed NCT NCT02916602

  A Study to Evaluate Efficacy and Safety of HCP1401 for Stage 2 Hypertension Patients Not Controlled by HCP0605

  Not yet reported Hanmi Pharmaceutical Company Limited 340 participants Est. completion 2016-09 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT03006796

  Observational Study of Azilsartan/Chlorthalidone and Irbesartan/Hydrochlorothiazide in Hypertension and Obesity.

  Russian Heart Failure Society 94 participants Est. completion 2020-03-31 1 site
  Other conditions: Arterial Hypertension
  View official trial listing →
• Completed NCT NCT03156634

  A Pilot Study of the Impact of the Patient Activated Learning System (PALS) on Knowledge Acquisition, Recall, and Decision Making

  Not yet reported Weill Medical College of Cornell University 118 participants Est. completion 2017-12-31 1 site
  Other conditions: Patient Education
  View official trial listing →
• Status unknown NCT NCT03226340

  S-amlodipine+Chlorthalidone vs S-amlodipine+Telmisartan in Hypertension

  Not yet reported Seoul National University Bundang Hospital 170 participants Est. completion 2018-03-31 10 sites
  Other conditions: Essential Hypertension
  View official trial listing →
• Terminated NCT NCT03325114

  Safety and Efficacy of Chlorthalidone in Type 1 Diabetes

  Not yet reported University of Rochester 1 participants Est. completion 2020-06-01 1 site
  Other conditions: Type 1 Diabetes Mellitus, Hypercalciuria
  View official trial listing →
• Completed NCT NCT03560804

  Use of Impedance Cardiography and Applanation Tonometry for Prediction of the Antihypertensive Effect of Two Drugs

  Not yet reported AHEPA University Hospital 60 participants Est. completion 2017-09-15 1 site
  Other conditions: Arterial Stiffness, Ambulatory Blood Pressure Monitoring
  View official trial listing →
• Completed NCT NCT03662620

  Clinical Trial to Compare the Safety and Pharmacokinetics of YH22162 in Healthy Volunteers

  Not yet reported Yuhan Corporation 67 participants Est. completion 2018-12-22 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT03666351

  Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV Disease

  Not yet reported Hanmi Pharmaceutical Company Limited 128 participants Est. completion 2022-07-25 1 site
  Other conditions: Aortic Stenosis, Aortic Regurgitation, Hypertension, LVM, Left Ventricular Hypertrophy
  View official trial listing →
• Completed NCT NCT03923933

  Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial

  Not yet reported Hospital General de México Dr. Eduardo Liceaga 34 participants Est. completion 2019-10-28 1 site
  Other conditions: Renal Insufficiency, Chronic
  View official trial listing →
• Status unknown NCT NCT03928145

  Efficacy of Chlorthalidone and Hydrochlorothiazide Combined With Amiloride on Blood Pressure in Primary Hypertension.

  Not yet reported Hospital de Clinicas de Porto Alegre 84 participants Est. completion 2021-07 1 site
  Other conditions: Hypertension
  View official trial listing →
• Withdrawn NCT NCT04192110

  Association of Diuretics With Change in Extracellular Volume, Natriuretic Peptides, Symptoms, and Cardiovascular Outcomes in CKD

  Not yet reported VA Office of Research and Development Est. completion 2020-08-11 1 site
  Chronic kidney disease
  View official trial listing →
• Suspended NCT NCT04330300

  Coronavirus (COVID-19) ACEi/ARB Investigation

  Not yet reported National University of Ireland, Galway, Ireland 2414 participants Est. completion 2021-12-01 1 site
  Other conditions: Hypertension, COVID-19
  View official trial listing →
• Completed NCT NCT04393493

  The Effect in Renal Function on Patients With Type 1 Cardiorenal Syndrome Treated With Two Strategies of Furosemide.

  Not yet reported Hospital Civil de Guadalajara 80 participants Est. completion 2020-04-01 2 sites
  Other conditions: Cardiorenal Syndrome
  View official trial listing →
• Completed NCT NCT04467931

  ACEI or ARB and COVID-19 Severity and Mortality in US Veterans

  University of Utah 22213 participants Est. completion 2020-12-31 1 site
  Other conditions: Hypertension, COVID
  View official trial listing →
• Completed NCT NCT04470830

  A Study for PMS of AZL-M/CLD FDC in the Treatment of Participants With Essential HTN in South Korea

  Celltrion Pharm, Inc. 718 participants Est. completion 2023-05-25 1 site
  Other conditions: Essential Hypertension
  View official trial listing →
• Completed NCT NCT04519164

  Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in Obesity

  Not yet reported Brigham and Women's Hospital 79 participants Est. completion 2025-09-17 1 site
  Metabolic syndrome Other conditions: Hypertension, Overweight and Obesity
  View official trial listing →
• Completed NCT NCT04757532

  Study of Exposure to Substances Prohibited by the World Anti-Doping Agency in Healthy Volunteers.

  Not yet reported Parc de Salut Mar 9 participants Est. completion 2021-03-10 1 site
  Other conditions: Healthy Volunteers
  View official trial listing →
• Completed NCT NCT04820907

  Clinical Efficacy and Safety Evaluation of HCP1904-1 in Essential Hypertension Patients

  Not yet reported Hanmi Pharmaceutical Company Limited 123 participants Est. completion 2021-09-30 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT04830449

  Clinical Efficacy and Safety Evaluation of HCP1904-2 in Essential Hypertension Patients

  Not yet reported Hanmi Pharmaceutical Company Limited 122 participants Est. completion 2021-08-24 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT04927299

  Efficacy and Safety of Losartan/Chlorthalidone vs Losartan/Hydrochlorothiazide in Essential Arterial Hypertension

  Not yet reported Laboratorios Silanes S.A. de C.V. 163 participants Est. completion 2023-09-11 1 site
  Other conditions: Essential Arterial Hypertension
  View official trial listing →
• Status unknown NCT NCT05077462

  A Clinical Trial to Evaluate the Safety and Pharmacokinetics of AJU-C52H in Healthy Volunteers

  Not yet reported AJU Pharm Co., Ltd. 60 participants Est. completion 2022-04-30 1 site
  Other conditions: Hypertension
  View official trial listing →
• Status unknown NCT NCT05077475

  A Clinical Trial to Evaluate the Safety and Pharmacokinetics of AJU-C52L in Healthy Volunteers

  Not yet reported AJU Pharm Co., Ltd. 60 participants Est. completion 2022-04-30 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT05090449

  Non-interaction Study of Chlorthalidone and Losartan in Fixed Combination, in Healthy Subjects, Under Fasting Conditions

  Not yet reported Laboratorios Silanes S.A. de C.V. 36 participants Est. completion 2020-05-25 1 site
  Other conditions: Healthy
  View official trial listing →
• Completed NCT NCT05171686

  Diuretics and Volume Overload in Early CKD

  Not yet reported VA Office of Research and Development 49 participants Est. completion 2025-10-02 1 site
  Chronic kidney disease Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT05199129

  Clinical Efficacy and Safety Evaluation of HCP1904-3 in Essential Hypertension Patients

  Not yet reported Hanmi Pharmaceutical Company Limited 166 participants Est. completion 2022-09-14 1 site
  Other conditions: Hypertension
  View official trial listing →
• Status unknown NCT NCT05222191

  Spironolactone in CKD Enabled by Chlorthalidone: PILOT

  Not yet reported Indiana Institute for Medical Research 24 participants Est. completion 2023-12-12 1 site
  Other conditions: Renal Insufficiency, Chronic Hypertension
  View official trial listing →
• Withdrawn NCT NCT05275907

  Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

  Not yet reported Northwestern University Est. completion 2023-10-04 1 site
  Other conditions: High Blood Pressure, Liver Transplant, Renal Function Abnormal
  View official trial listing →
• Terminated NCT NCT05370599

  Hypertension in Young Adults Trial

  Not yet reported University of California, San Francisco 36 participants Est. completion 2026-01-07 1 site
  Other conditions: Hypertension
  View official trial listing →
• Completed NCT NCT05411991

  Diuretic Treatment in Acute Heart Failure With Volume Overload Guided by Serial Spot Urine Sodium Assessment

  Not yet reported Vrije Universiteit Brussel 107 participants Est. completion 2024-07-01 2 sites
  Heart failure Other conditions: Diuretics Drug Reactions
  View official trial listing →
• Completed NCT NCT05462535

  An Observational Study to Evaluate Effectiveness and Safety of Amosartan Plus Tablet

  Hanmi Pharmaceutical Company Limited 4785 participants Est. completion 2021-07-15 1 site
  Other conditions: Hypertension,Essential
  View official trial listing →
• Status unknown NCT NCT05580510

  " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD "

  Not yet reported, Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 160 participants Est. completion 2024-03-29 1 site
  Heart failure Other conditions: Congenital Heart Disease
  View official trial listing →
• Terminated NCT NCT05915286

  Diuretic Use in Hemodialysis Patients With Residual Renal Function

  Not yet reported University of Alberta 2 participants Est. completion 2025-02-21 1 site
  Other conditions: End Stage Renal Disease on Dialysis
  View official trial listing →
• Completed NCT NCT05920005

  Candesartan Cilexetil + Chlorthalidone + Amlodipine Versus Exforge HCT®️ for Systemic Arterial Hypertension

  Not yet reported Hospital Israelita Albert Einstein 702 participants Est. completion 2025-05-01 22 sites
  Other conditions: Hypertension
  View official trial listing →
• Status unknown NCT NCT05976438

  Skin Sodium and Salt Sensitivity of Blood Pressure

  Not yet reported Cambridge University Hospitals NHS Foundation Trust 60 participants Est. completion 2024-12 2 sites
  Other conditions: Hypertension
  View official trial listing →
• Active, not recruiting NCT NCT06041529

  Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients With Essential Hypertension

  Not yet reported Yuhan Corporation 198 participants Est. completion 2026-02-28 15 sites
  Other conditions: Essential Hypertension
  View official trial listing →
• Active, not recruiting NCT NCT06282549

  Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients with Essential Hypertension

  Yuhan Corporation 1219 participants Est. completion 2027-03-31 5 sites
  Other conditions: Essential Hypertension
  View official trial listing →
• Completed NCT NCT06287580

  Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension.

  Not yet reported University of Texas Southwestern Medical Center 27 participants Est. completion 2026-02-20 1 site
  Other conditions: Essential Hypertension, Older Adults
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• Completed NCT NCT07116863

  A Multicenter, Randomized, Double-Blind Phase 3 Trial of KDF1901 in Patients With Essential Hypertension

  Not yet reported Kyungdong Pharmaceutical Co., Ltd. 286 participants Est. completion 2024-09-13 2 sites
  Other conditions: Essential Hypertension
  View official trial listing →
• Not yet recruiting NCT NCT07645300

  LOw DosE Spironolactone, chlorThAlidone oR Combination in CKD Trial

  Not yet reported VA Office of Research and Development 160 participants Est. completion 2032-06-30 1 site
  Chronic kidney disease Other conditions: Hypertension Treated With Antihypertensive Drugs
  View official trial listing →

Not yet reported.

Not yet reported.

• ClinicalTrials.gov — NCT04519164

Also known as: Chlorthalidone with potassium chloride, hygroton

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