About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Cadisegliatin

Company: vTv Therapeutics
Mechanism: Mechanism not yet reported
Route: Route not yet reported
Recruiting trials: None currently listed

Efficacy results: Not yet reported

No recruiting studies currently listed

See all studies for this drug

Data source: ClinicalTrials.gov · trial data as of Sep 22, 2026

Trial details

Completed NCT NCT01474083

A 6 Week Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of GK1-399 in Type 2 Diabetes

Not yet reported, Not yet reported vTv Therapeutics 248 participants Est. completion 2012-09 11 sites Stand-alone

Type 2 diabetes
View official trial listing →
Completed NCT NCT02405260

Add Glucokinase Activator to Target A1c

Not yet reported vTv Therapeutics 190 participants Est. completion 2016-09 20 sites Stand-alone

Type 2 diabetes
View official trial listing →
Completed NCT NCT03335371

Evaluation of TTP399 in Patients With Type 1 Diabetes

Not yet reported, Not yet reported vTv Therapeutics 115 participants Est. completion 2020-01-06 15 sites Stand-alone

Other conditions: Diabetes Mellitus, Type 1
View official trial listing →
Active, not recruiting NCT NCT06334133

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes

Not yet reported vTv Therapeutics 150 participants Est. completion 2027-05 52 sites Stand-alone

Other conditions: Diabetes Mellitus, Type 1
View official trial listing →
Not yet recruiting NCT NCT07616206

Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes Who Are Using Hybrid Closed Loop (HCL) Systems

Not yet reported vTv Therapeutics 40 participants Est. completion 2027-06 1 site Stand-alone

Other conditions: Type 1 Diabetes (T1D)
View official trial listing →

Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

ClinicalTrials.gov — NCT07616206

Also known as: Cadisegliatin, Cadisegliatin 800 mg QD, TTP399

Related On The Pen coverage

No related coverage yet.

This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.