-
Terminated
NCT NCT05153330
Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL
Not yet reported
Biomea Fusion Inc.
55 participants
Est. completion 2025-05-02
41 sites
Stand-alone
Other conditions: Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Acute Mixed-Phenotype Leukemia, Cancer, Refractory, Progression, Diffuse Large B Cell Lymphoma, Multiple Myeloma, Lymphoma, Lymphoma, Non-Hodgkin, Myeloma, Plasma-Cell, Myelomatosis, Plasma Cell Myeloma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
View official trial listing →
-
Terminated
NCT NCT05631574
Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer
Not yet reported
Biomea Fusion Inc.
13 participants
Est. completion 2025-01-15
23 sites
Stand-alone
Other conditions: Non Small Cell Lung Cancer, Pancreatic Cancer, Colorectal Cancer, NSCLC, PDAC, CRC, Relapsed Cancer, Refractory Cancer, Stage III Pancreatic Cancer, Stage IV Pancreatic Cancer, Stage III Non-small Cell Lung Cancer, Stage IV Non-small Cell Lung Cancer, Stage III Colorectal Cancer, Stage IV Colorectal Cancer, Stage III NSCLC, Stage IV NSCLC, KRAS Mutation-Related Tumors
View official trial listing →
-
Completed
NCT NCT05731544
Study of BMF-219 in Healthy Adult Subjects and in Adult Subjects With Type 2 Diabetes Mellitus (T2D)
Not yet reported, Not yet reported
Biomea Fusion Inc.
443 participants
Est. completion 2025-07-08
39 sites
Stand-alone
Type 2 diabetes
View official trial listing →
-
Completed
NCT NCT06152042
Phase 2 Trial of BMF-219 in Participants With Type 1 Diabetes Mellitus
Not yet reported
Biomea Fusion Inc.
37 participants
Est. completion 2025-07-18
11 sites
Stand-alone
Other conditions: Type 1 Diabetes Mellitus
View official trial listing →
-
Completed
NCT NCT07254286
Food Effect Study in Healthy Volunteers
Not yet reported
Biomea Fusion Inc.
60 participants
Est. completion 2026-01-14
1 site
Other conditions: Healthy Volunteer
View official trial listing →