About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Benazepril Hydrochloride
- Company
- Baylor Research Institute
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 1 recruiting
Efficacy results: Not yet reported
1 recruiting study currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 14, 2026
Find a Clinical Trial Near Me
See recruiting studies for Benazepril Hydrochloride and check eligibility with the study team.
Trial details
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Recruiting NCT NCT05498675
Effect of Sacubitril/Valsartan on Cardiac Function in Hypertensive Patients Stratified by BMI: A Real World Study
Beijing Friendship Hospital 180 participants Est. completion 2027-06-30 1 siteOther conditions: Sacubitril/Valsartan, Hypertension, ObesityView official trial listing → -
Completed NCT NCT00000620
Action to Control Cardiovascular Risk in Diabetes (ACCORD)
Not yet reported National Heart, Lung, and Blood Institute (NHLBI) 10251 participants Est. completion 2012-12 7 sitesCardiovascular diseaseType 2 diabetes Other conditions: Atherosclerosis, Hypercholesterolemia, Hypertension, Diabetes Mellitus, Coronary DiseaseView official trial listing → -
Completed NCT NCT00136773
Effects of Amlodipine/Benazepril on Albuminuria in Hypertensive Patients With Type 2 Diabetes Mellitus
Not yet reported Novartis 332 participants Est. completion 2005-11Other conditions: AlbuminuriaView official trial listing → -
Completed NCT NCT00136851
Study Comparing the Efficacy of Amlodipine Besylate/Benazepril Versus Amlodipine in the Treatment of Severe Hypertension
Not yet reported Novartis Pharmaceuticals 259 participants Est. completion 2005-07 1 siteOther conditions: HypertensionView official trial listing → -
Completed NCT NCT00139555
Effects of Amlodipine/Benazepril in Reducing Left Ventricular Hypertrophy in Patients With High Risk Hypertension
Not yet reported Novartis 125 participants Est. completion 2006-11 1 siteOther conditions: Hypertension, Left Ventricular HypertrophyView official trial listing → -
Terminated NCT NCT00170950
Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension
Not yet reported Novartis 11506 participants Est. completion 2008-05 5 sites Stand-aloneOther conditions: HypertensionView official trial listing → -
Terminated NCT NCT00171119
A Study in Patients With Diabetes Mellitus Type II of the Effect on Albuminuria of 24 Week Treatment With Valsartan, Benazepril, and Valsartan+Benazepril
Not yet reported Novartis Pharmaceuticals 81 participants 1 siteChronic kidney disease Other conditions: HypertensionView official trial listing → -
Completed NCT NCT00171366
A Study Comparing the Response of Patients With Hypertension to Amlodipine or Amlodipine Plus Benazepril.
Not yet reported Novartis 1422 participants Est. completion 2005-07 1 siteOther conditions: HypertensionView official trial listing → -
Completed NCT NCT00185120
Treatment of High Blood Pressure Using Olmesartan With Hydrochlorothiazide Compared to an ACE Inhibitor With a Calcium Channel Blocker
Not yet reported Daiichi Sankyo 152 participants Est. completion 2006-09 20 sitesOther conditions: HypertensionView official trial listing → -
Completed NCT NCT00234871
Tarka® vs. Lotrel® in Hypertensive, Diabetic Subjects With Renal Disease (TANDEM)
Not yet reported Abbott 357 participantsOther conditions: Hypertension, Diabetes, ProteinuriaView official trial listing → -
Terminated NCT NCT00270426
Benazepril for Advanced Chronic Renal Insufficiency
Not yet reported Southern Medical University, ChinaOther conditions: Chronic Kidney FailureView official trial listing → -
Completed NCT NCT00309257
Effects of an Intensified Treatment With ACE-I,ATA II and Statins in Alport Syndrome
Not yet reported Mario Negri Institute for Pharmacological Research 9 participants Est. completion 2009-10 1 site Stand-aloneOther conditions: Alport SyndromeView official trial listing → -
Terminated NCT NCT00338091
Long-Term Renoprotection of Optimal Antiproteinuric Doses of Benazepril and Losartan in Chronic Renal Insufficiency
Not yet reported Southern Medical University, China Est. completion 2006-05 1 siteOther conditions: Renal Insufficiency,Chronic, Disease Progression, Proteinuria, Dose-Response Relationship,Drug, ACE Inhibitor, Angiotensin II Type 1 Receptor BlockersView official trial listing → -
Completed NCT NCT00367094
Combination of Benazepril Plus Hydrochlorothiazide in Chinese Patients With Mild to Moderate Essential Hypertension
Not yet reported Novartis 296 participants 1 siteOther conditions: HypertensionView official trial listing → -
Completed NCT NCT00367978
Effects of Amlodipine/Benazepril in the Hypertensive African-American Population With Type 2 Diabetes Mellitus
Not yet reported Novartis 275 participants Est. completion 2003-09 1 siteOther conditions: HypertensionView official trial listing → -
Completed NCT NCT00494715
Preventing ESRD in Overt Nephropathy of Type 2 Diabetes
Not yet reported Mario Negri Institute for Pharmacological Research 102 participants Est. completion 2016-04 15 sites Stand-aloneOther conditions: DiabetesView official trial listing → -
Completed NCT NCT00503152
Preventing Microalbuminuria in Type 2 Diabetes
Not yet reported Mario Negri Institute for Pharmacological Research 612 participants Est. completion 2016-09 9 sites Stand-aloneOther conditions: DiabetesView official trial listing → -
Terminated NCT NCT00630708
Safety of Dual Blockage of Rennin-angiotensin System in Patients With Advanced Renal Insufficiency
Not yet reported Nanfang Hospital, Southern Medical University 309 participants Est. completion 2014-03 1 siteOther conditions: Renal Insufficiency, ChronicView official trial listing → -
Completed NCT NCT00649038
Fed Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg
Not yet reported Mylan Pharmaceuticals Inc 24 participants Est. completion 2002-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00649402
Fed Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg
Not yet reported Mylan Pharmaceuticals Inc 64 participants Est. completion 2004-06 1 site Stand-aloneOther conditions: HealhtyView official trial listing → -
Completed NCT NCT00649519
Fasting Study of Amlodipine and Benazepril HCl Capsules 10 mg/20 mg to Lotrel® Capsules 10 mg/20 mg
Not yet reported Mylan Pharmaceuticals Inc 54 participants Est. completion 2004-05 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00649597
Fasting Study of Benazepril HCl and Hydrochlorothiazide Tablets 20 mg/25 mg to Lotensin HCT® Tablets 20 mg/25 mg
Not yet reported Mylan Pharmaceuticals Inc 56 participants Est. completion 2002-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00664846
Standard Medical Management in Secondary Prevention of Ischemic Stroke in China
Not yet reported Peking Union Medical College Hospital 4000 participants Est. completion 2011-04 46 sites Stand-aloneCardiovascular diseaseView official trial listing → -
Completed NCT NCT00684489
Renin-Guided Therapeutics in the Management of Untreated, Uncontrolled, or Complicated Hypertension
Not yet reported Medical University of South Carolina 52 participants Est. completion 2005-09Other conditions: HypertensionView official trial listing → -
Completed NCT NCT00691314
Efficacy and Safety of Stent Implantation in Symptomatic Extra- and Intracranial Artery Stenosis
Not yet reported Peking Union Medical College Hospital 300 participants Est. completion 2010-12 10 sites Stand-aloneCardiovascular disease Other conditions: Transient Ischemic Attack, Atherosclerosis, Stenosis, StentsView official trial listing → -
Completed NCT NCT00721773
Renal Protective Effects of Renin Angiotensin System (RAS) Inhibitor in Peritoneal Dialysis Patients
Not yet reported Sun Yat-sen University 200 participants Est. completion 2014-10 1 site Stand-aloneOther conditions: Renal Function DisorderView official trial listing → -
Completed NCT NCT00778674
Bioequivalence Study of Benazepril HCl / Hydrochlorothiazide 20 mg/ 25 mg Tablets Under Fed Conditions
Not yet reported Ranbaxy Laboratories Limited 30 participants Est. completion 2004-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00778726
Bioequivalence Study of Benazepril HCl / Hydrochlorothiazide 20 mg/ 25 mg Tablets Under Fasting Conditions
Not yet reported Ranbaxy Laboratories Limited 42 participants Est. completion 2004-12 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00834977
Amlodipine-Benazepril 10mg-20mg Capsules in Healthy Subjects Under Fasting Conditions
Not yet reported Teva Pharmaceuticals USA 48 participants Est. completion 2004-05 2 sites Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00835367
Amlodipine-Benazepril 10mg-20mg Capsules in Healthy Subjects Under Fed Conditions
Not yet reported Teva Pharmaceuticals USA 68 participants Est. completion 2004-03 2 sites Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00836537
Benazepril HCl 40 mg Tablets, Fed
Not yet reported Teva Pharmaceuticals USA 40 participants Est. completion 2001-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00836576
Benazepril HCl 40 mg Tablets, Fasting
Not yet reported Teva Pharmaceuticals USA 40 participants Est. completion 2001-03 1 site Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT00907374
Low Dose Versus Aggressive Inhibition of the Renin-Angiotensin-Aldosterone (RAS) to Treat Microalbuminuria
Not yet reported Charles Drew University of Medicine and Science 46 participants Est. completion 2009-04 1 site Stand-aloneOther conditions: MicroalbuminuriaView official trial listing → -
Completed NCT NCT01095939
Post-preeclampsia Renal Project: Study of Nephroprotection in Women Having Suffered Preeclampsia
Not yet reported University Hospital, Geneva 120 participants Est. completion 2018-03 2 sites Stand-aloneOther conditions: Renal AlterationView official trial listing → -
Completed NCT NCT01155895
Bioequivalence Study of 10 mg Amlodipine Besylate/ 20 mg Benazepril Hydrochloride Capsules of Dr.Reddys Laboratories Limited Under Fasting Conditions
Not yet reported Dr. Reddy's Laboratories Limited 54 participants Est. completion 2004-04 Stand-aloneOther conditions: HealthyView official trial listing → -
Completed NCT NCT01155908
Bioequivalence Study of 10 mg Amlodipine Besylate/ 20 mg Benazepril Hydrochloride Capsules of Dr.Reddys Laboratories Limited Under Non-fasting (Fed) Conditions
Not yet reported Dr. Reddy's Laboratories Limited 48 participants Est. completion 2005-05 Stand-aloneOther conditions: HealthyView official trial listing → -
Terminated NCT NCT01234922
Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid Tumors
Not yet reported Wake Forest University Health Sciences 6 participants Est. completion 2014-04 1 site Stand-aloneOther conditions: Hypertension, Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Completed NCT NCT01375322
ADDM Study - Amtrel and Co-Diovan in Type 2 Diabetes Mellitus Hypertension Patients With Microalbuminuria
Not yet reported TSH Biopharm Corporation Limited 226 participants Est. completion 2010-06 4 sites Stand-aloneType 2 diabetes Other conditions: Hypertension, AlbuminuriaView official trial listing → -
Completed NCT NCT01505998
Bioequivalence Study of Amlodipine Besylate/Benazepril HCl 10 mg/40 mg Capsules of Dr. Reddy's Under Fed Conditions
Not yet reported Dr. Reddy's Laboratories Limited 49 participants Est. completion 2007-05 1 site Stand-aloneOther conditions: FedView official trial listing → -
Completed NCT NCT01506011
Bioequivalence Study of Amlodipine Besylate/Benazepril HCl 10 mg/40 mg Capsules of Dr. Reddy's Under Fasting Conditions
Not yet reported Dr. Reddy's Laboratories Limited 50 participants Est. completion 2007-04 1 site Stand-aloneOther conditions: FastingView official trial listing → -
Completed NCT NCT01603940
Comparison Between Losartan and Benazepril in Diabetic Hypertensive Patients Not Controlled by Amlodipine
Not yet reported Hospital Universitario Pedro Ernesto 30 participants Est. completion 2015-01 1 siteOther conditions: Hypertension, Diabetes MellitusView official trial listing → -
Completed NCT NCT01669434
Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery
Not yet reported University of Nebraska 291 participants Est. completion 2016-12-01 1 siteOther conditions: Hypotension on InductionView official trial listing → -
Status unknown NCT NCT01715584
Is There an Adverse Drug Reaction Between Renin-Angiotensin System Blockade and Inhaled Anesthetics
Not yet reported London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 80 participants Est. completion 2019-12-31 1 siteOther conditions: HypertensionView official trial listing → -
Terminated NCT NCT01867047
ACE-Inhibitor Effects on Total Hip and Knee Arthroplasty Patients
Not yet reported Duke University 59 participants Est. completion 2016-06-24 1 site Stand-aloneOther conditions: Adverse Effects of Angiotensin-converting-enzyme Inhibitors, HypotensionView official trial listing → -
Completed NCT NCT01917149
Supramaximal Titrated Inhibition of RAAS in Dilated Cardiomyopathy
Not yet reported Xijing Hospital 480 participants Est. completion 2013-12 1 site Stand-aloneOther conditions: Dilated CardiomyopathyView official trial listing → -
Status unknown NCT NCT02532777
The Research of Standard Diagnosis and Treatment for HSPN in Children
Not yet reported Nanjing Children's Hospital 100 participants Est. completion 2020-07 1 siteOther conditions: Henoch-Schoenlein Purpura NephritisView official trial listing → -
Status unknown NCT NCT02532790
The Research of Standard Diagnosis and Treatment for HSPN With Mild Proteinuria in Children
Not yet reported Nanjing Children's Hospital 100 participants Est. completion 2020-07 1 site Stand-aloneOther conditions: Henoch-Schoenlein Purpura NephritisView official trial listing → -
Status unknown NCT NCT03591471
Study on Children Henoch-Schönlein Purpura Nephritis With TCM Multistep Treatment
Not yet reported, Not yet reported Henan University of Traditional Chinese Medicine 500 participants Est. completion 2018-12 2 sitesOther conditions: Henoch-Schönlein Purpura NephritisView official trial listing → -
Completed NCT NCT03682692
ACEI/CCB Versus ACEI/DIU Combination Antihypertensive Therapy in Chinese Hypertensive Patients (ACvAD)
Not yet reported Shanghai Jiao Tong University School of Medicine 560 participants Est. completion 2022-03-31 1 site Stand-aloneOther conditions: HypertensionView official trial listing → -
Suspended NCT NCT04330300
Coronavirus (COVID-19) ACEi/ARB Investigation
Not yet reported National University of Ireland, Galway, Ireland 2414 participants Est. completion 2021-12-01 1 siteOther conditions: Hypertension, COVID-19View official trial listing → -
Completed NCT NCT04467931
ACEI or ARB and COVID-19 Severity and Mortality in US Veterans
University of Utah 22213 participants Est. completion 2020-12-31 1 siteOther conditions: Hypertension, COVIDView official trial listing → -
Active, not recruiting NCT NCT04486118
Centrally Acting ACE Inhibition in SLE
Not yet reported Northwell Health 36 participants Est. completion 2026-03-01 7 sitesOther conditions: Systemic Lupus ErythematosusView official trial listing → -
Completed NCT NCT04937907
Study of Hydroxychloroquine in Patients With X-linked Alport Syndrome in China (CHXLAS)
Not yet reported Shanghai Children's Hospital 50 participants Est. completion 2024-12-31 1 site Stand-aloneOther conditions: Alport Syndrome, X-LinkedView official trial listing → -
Status unknown NCT NCT05670028
Cerebral Autoregulation Guiding Blood Pressure Management After Revascularization
Not yet reported Beijing Tiantan Hospital 100 participants Est. completion 2026-06-04 Stand-aloneCardiovascular disease Other conditions: Revascularization, Blood Pressure, Cerebrovascular Insufficiency, Cerebral Autoregulation, IndividuationView official trial listing → -
Not yet recruiting NCT NCT07262710
Association of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers With Post-Stroke Pneumonia: A Real-World Retrospective Cohort Study
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine 13656 participants Est. completion 2026-08-19Cardiovascular diseaseView official trial listing → -
Not yet recruiting NCT NCT07486453
Bioequivalence Study of Sacubitril Alisartan Amlodipine Tablets
Not yet reported Shenzhen Salubris Pharmaceuticals Co., Ltd. 60 participants Est. completion 2026-04-25 1 site Stand-aloneOther conditions: Primary HypertensionView official trial listing → -
Enrolling by invitation NCT NCT07547878
Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)
Not yet reported Baylor Research Institute 64 participants Est. completion 2029-03-31 1 siteChronic kidney diseaseType 2 diabetesView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Benazepril Hydrochloride, Lotensin, Lotensin HCT, Benazepril
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This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
