About this data
Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.
Atezolizumab
- Company
- National Cancer Institute (NCI)
- Mechanism
- Mechanism not yet reported
- Route
- Route not yet reported
- Recruiting trials
- 204 recruiting
Efficacy results: Not yet reported
204 recruiting studies currently listed on ClinicalTrials.gov.
Data source: ClinicalTrials.gov · trial data as of Oct 23, 2026
Find a Clinical Trial Near Me
See recruiting studies for Atezolizumab and check eligibility with the study team.
Trial details
-
Recruiting NCT NCT02693535
TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer
Not yet reported American Society of Clinical Oncology 4200 participants Est. completion 2028-12-31 181 sitesOther conditions: Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid TumorsView official trial listing → -
Recruiting NCT NCT02925234
The Drug Rediscovery Protocol (DRUP Trial)
Not yet reported The Netherlands Cancer Institute 1550 participants Est. completion 2027-12 36 sites Stand-aloneOther conditions: Cancer, Tumors, Neoplasm, NeoplasiaView official trial listing → -
Recruiting NCT NCT03424005
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer
Not yet reported, Not yet reported Hoffmann-La Roche 1132 participants Est. completion 2030-09-30 55 sites Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT03548428
Stereotaxic Body Irradiation of Oligometastase in Sarcoma (Stereosarc)
Not yet reported Centre Antoine Lacassagne 103 participants Est. completion 2031-02-04 17 sites Stand-aloneOther conditions: Sarcoma, RadiosurgeryView official trial listing → -
Recruiting NCT NCT03767075
A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets)
Not yet reported Vall d'Hebron Institute of Oncology 1000 participants Est. completion 2026-11 8 sites Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Recruiting NCT NCT03821246
Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy
Not yet reported David Oh 68 participants Est. completion 2027-04-30 2 sites Stand-aloneOther conditions: Prostate Adenocarcinoma, Prostate Cancer, Localized Prostate CancerView official trial listing → -
Recruiting NCT NCT03942328
Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer
Not yet reported, Not yet reported Mayo Clinic 85 participants Est. completion 2030-08-31 1 site Stand-aloneOther conditions: Stage III Hepatocellular Carcinoma AJCC v8, Stage III Intrahepatic Cholangiocarcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8, Stage IV Intrahepatic Cholangiocarcinoma AJCC v8, Unresectable Hepatocellular Carcinoma, Unresectable Intrahepatic CholangiocarcinomaView official trial listing → -
Recruiting NCT NCT04253964
Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy
Not yet reported Wake Forest University Health Sciences 105 participants Est. completion 2027-09-01 2 sites Stand-aloneOther conditions: Nonsmall Cell Lung Cancer, Performance StatusView official trial listing → -
Recruiting NCT NCT04273061
Investigating the Effects of Atezolizumab in People Whose Tumour DNA or RNA Indicates Possible Sensitivity
Not yet reported British Columbia Cancer Agency 50 participants Est. completion 2027-10 2 sites Stand-aloneOther conditions: Breast Cancer, Lung Cancer, Gastrointestinal Cancer, Genitourinary Cancer, Gynecologic Cancer, Sarcoma, Unknown Primary Tumors, Head and Neck Cancer, Skin CancerView official trial listing → -
Recruiting NCT NCT04294771
JOint Use of Database to Identify Risk Factors of CARDio-vascular Toxicity Induced by Immune Checkpoint Inhibitors
Groupe Hospitalier Pitie-Salpetriere 500000 participants Est. completion 2030-01-01 1 siteCardiovascular disease Other conditions: Myocarditis, Cardiomyopathies, Heart Diseases, Pericarditis, VasculitisView official trial listing → -
Recruiting NCT NCT04302025
A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
Not yet reported Genentech, Inc. 99 participants Est. completion 2030-05-30 38 sites Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT04341181
ProTarget - A Danish Nationwide Clinical Trial on Targeted Cancer Treatment Based on Genomic Profiling
Not yet reported Ulrik Lassen 300 participants Est. completion 2030-04-30 7 sites Stand-aloneOther conditions: Cancer, Tumors, Neoplasms, NeoplasiaView official trial listing → -
Recruiting NCT NCT04423185
PLATFORM Study of Precision Medicine for Rare Tumors
Not yet reported Cancer Institute and Hospital, Chinese Academy of Medical Sciences 770 participants Est. completion 2028-07-01 1 site Stand-aloneOther conditions: Rare TumorView official trial listing → -
Recruiting NCT NCT04434040
Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)
Not yet reported Dana-Farber Cancer Institute 40 participants Est. completion 2027-12-30 7 sites Stand-aloneOther conditions: Breast Cancer, Triple Negative Breast Cancer, Residual Cancer, Circulating Tumor DNAView official trial listing → -
Recruiting NCT NCT04467723
Combination of Atezolizumab and Pirfenidone in Second-line and Beyond NSCLC
Not yet reported, Not yet reported University of Kansas Medical Center 25 participants Est. completion 2027-08 2 sites Stand-aloneOther conditions: NSCLC Stage IV, NSCLC, RecurrentView official trial listing → -
Recruiting NCT NCT04486352
A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer
Not yet reported, Not yet reported Alliance Foundation Trials, LLC. 148 participants Est. completion 2027-10 21 sites Stand-aloneOther conditions: Endometrial CancerView official trial listing → -
Recruiting NCT NCT04691817
Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy
Not yet reported, Not yet reported Abramson Cancer Center at Penn Medicine 28 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: Lung Cancer, Nonsmall CellView official trial listing → -
Recruiting NCT NCT04696575
Lamivudine in Combination With Chemoimmunotherapy for the Treatment of Extensive Stage Small Cell Lung Cancer
Not yet reported Roswell Park Cancer Institute 28 participants Est. completion 2027-07-01 1 site Stand-aloneOther conditions: Extensive Stage Lung Small Cell CarcinomaView official trial listing → -
Recruiting NCT NCT04770207
Intra-tumor Injection of Drug-eluting Microspheres With Multiple Drugs
Not yet reported Second Affiliated Hospital of Guangzhou Medical University 100 participants Est. completion 2035-11-01 1 siteOther conditions: Hepatocellular Carcinoma, Solid Tumor, AdultView official trial listing → -
Recruiting NCT NCT04796012
VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors
Not yet reported, Not yet reported University of Texas Southwestern Medical Center 23 participants Est. completion 2027-01 7 sites Stand-aloneObstructive sleep apnea Other conditions: Solid TumorView official trial listing → -
Recruiting NCT NCT04802759
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
Not yet reported, Not yet reported Hoffmann-La Roche 316 participants Est. completion 2029-05-30 32 sites Stand-aloneOther conditions: Inoperable, Locally Advanced or Metastatic, ER-positive Breast CancerView official trial listing → -
Recruiting NCT NCT04803994
The ABC-HCC Trial: Atezolizumab Plus Bevacizumab vs. Transarterial Chemoembolization (TACE) in Intermediate-stage HepatoCellular Carcinoma
Not yet reported Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 434 participants Est. completion 2027-07 72 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT04812366
Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer
Not yet reported University of British Columbia 315 participants Est. completion 2027-06-01 9 sitesOther conditions: Prostate CancerView official trial listing → -
Recruiting NCT NCT04817956
Improving Public Cancer Care by Implementing Precision Medicine in Norway
Not yet reported Oslo University Hospital 3000 participants Est. completion 2045-04-30 17 sites Stand-aloneOther conditions: Cancer MetastaticView official trial listing → -
Recruiting NCT NCT04819243
PALbociclib Endocrine Therapy Followed by Talazo Vs. Talazoz-Atezo Study
Not yet reported Samsung Medical Center 178 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Premenopausal HR+/HER2- Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT04865250
Predicting Response to Neoadjuvant ATEZOLIZUMAB Plus Carboplatin/Nab Paclitaxel in Resectable Non-squamous NSCLC
Not yet reported University Hospital Heidelberg 20 participants Est. completion 2026-12-30 1 site Stand-aloneOther conditions: NSCLC Stage II, NSCLC, Stage IIIA, NSCLC Stage IIIBView official trial listing → -
Recruiting NCT NCT04919382
Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer
Not yet reported Dwight Owen 56 participants Est. completion 2028-12-30 5 sites Stand-aloneOther conditions: Extensive Stage Lung Small Cell Carcinoma, Metastatic Lung Small Cell Carcinoma, Recurrent Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8View official trial listing → -
Recruiting NCT NCT04929223
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
Not yet reported Hoffmann-La Roche 542 participants Est. completion 2030-08-31 84 sites Stand-aloneOther conditions: Metastatic Colorectal CancerView official trial listing → -
Recruiting NCT NCT04954599
Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI
Not yet reported, Not yet reported Maastricht University Medical Center 126 participants Est. completion 2027-05 5 sitesOther conditions: Unspecified Adult Solid Tumor, Protocol SpecificView official trial listing → -
Recruiting NCT NCT04981509
Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer
Not yet reported National Cancer Institute (NCI) 65 participants Est. completion 2027-12-31 13 sites Stand-aloneOther conditions: Hereditary Leiomyomatosis and Renal Cell Carcinoma, Papillary Renal Cell Carcinoma, Renal Cell Carcinoma, Sporadic Papillary Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8View official trial listing → -
Recruiting NCT NCT04996017
Atezolizumab Versus Placebo for the Adjuvant Treatment of Malignant Pleural Mesothelioma (Atezomeso)
Not yet reported Gruppo Oncologico Italiano di Ricerca Clinica 162 participants Est. completion 2029-06-30 19 sites Stand-aloneOther conditions: Mesotheliomas PleuralView official trial listing → -
Recruiting NCT NCT05000294
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
Not yet reported, Not yet reported University of Florida 29 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Bile Duct Cancer, Gall Bladder Cancer, Breast Cancer, Neuroendocrine Tumors, Ovarian Cancer, Pancreatic Adenocarcinoma, Soft Tissue Sarcoma, Vulvar Cancer, Prostate CancerView official trial listing → -
Recruiting NCT NCT05001880
Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma
Not yet reported National Cancer Institute (NCI) 66 participants Est. completion 2027-08-01 40 sites Stand-aloneOther conditions: Peritoneal Malignant MesotheliomaView official trial listing → -
Recruiting NCT NCT05019703
Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study
Not yet reported M.D. Anderson Cancer Center 40 participants Est. completion 2027-12-31 2 sites Stand-aloneObstructive sleep apneaView official trial listing → -
Recruiting NCT NCT05055908
Efficacy and Biomarker Development for Lung Cancer Treated With Immune Checkpoint Inhibitors
Not yet reported Hunan Province Tumor Hospital 12000 participants Est. completion 2027-09-14 1 site Stand-aloneOther conditions: Lung CancerView official trial listing → -
Recruiting NCT NCT05058651
Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung
Not yet reported, Not yet reported National Cancer Institute (NCI) 189 participants Est. completion 2028-10-01 265 sites Stand-aloneOther conditions: Advanced Extrapulmonary Neuroendocrine Carcinoma, Metastatic Extrapulmonary Neuroendocrine Carcinoma, Recurrent Extrapulmonary Neuroendocrine Carcinoma, Unresectable Extrapulmonary Neuroendocrine CarcinomaView official trial listing → -
Recruiting NCT NCT05085496
Radiotherapy in Combination With Atezolizumab in Locally Advanced Borderline Resectable or Unresectable Cutaneous SCC
Not yet reported City of Hope Medical Center 12 participants Est. completion 2027-09-10 1 site Stand-aloneOther conditions: Locally Advanced Skin Squamous Cell Carcinoma, Resectable Skin Squamous Cell Carcinoma, Unresectable Skin Squamous Cell CarcinomaView official trial listing → -
Recruiting NCT NCT05092373
Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax
Not yet reported M.D. Anderson Cancer Center 43 participants Est. completion 2026-09-01 1 site Stand-aloneOther conditions: Advanced Breast Carcinoma, Advanced Endometrial Carcinoma, Advanced Fallopian Tube Carcinoma, Advanced Hepatocellular Carcinoma, Advanced Malignant Abdominal Neoplasm, Advanced Malignant Female Reproductive System Neoplasm, Advanced Malignant Thoracic Neoplasm, Advanced Ovarian Carcinoma, Advanced Primary Peritoneal Carcinoma, Advanced Renal Cell Carcinoma, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Malignant Abdominal Neoplasm, Malignant Solid Neoplasm, Metastatic Breast Carcinoma, Metastatic Endometrial Carcinoma, Metastatic Fallopian Tube Carcinoma, Metastatic Hepatocellular Carcinoma, Metastatic Malignant Abdominal Neoplasm, Metastatic Malignant Female Reproductive System Neoplasm, Metastatic Malignant Thoracic Neoplasm, Metastatic Ovarian Carcinoma, Metastatic Primary Peritoneal Carcinoma, Metastatic Renal Cell Carcinoma, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8, Prognostic Stage IV Breast Cancer AJCC v8, Stage III Fallopian Tube Cancer AJCC v8, Stage III Hepatocellular Carcinoma AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage III Primary Peritoneal Cancer AJCC v8, Stage III Renal Cell Cancer AJCC v8, Stage III Uterine Corpus Cancer AJCC v8, Stage IIIA Fallopian Tube Cancer AJCC v8, Stage IIIA Hepatocellular Carcinoma AJCC v8, Stage IIIA Ovarian Cancer AJCC v8, Stage IIIA Primary Peritoneal Cancer AJCC v8, Stage IIIA Uterine Corpus Cancer AJCC v8, Stage IIIA1 Fallopian Tube Cancer AJCC v8, Stage IIIA1 Ovarian Cancer AJCC v8, Stage IIIA2 Fallopian Tube Cancer AJCC v8, Stage IIIA2 Ovarian Cancer AJCC v8, Stage IIIB Fallopian Tube Cancer AJCC v8, Stage IIIB Hepatocellular Carcinoma AJCC v8, Stage IIIB Ovarian Cancer AJCC v8, Stage IIIB Primary Peritoneal Cancer AJCC v8, Stage IIIB Uterine Corpus Cancer AJCC v8, Stage IIIC Fallopian Tube Cancer AJCC v8, Stage IIIC Ovarian Cancer AJCC v8, Stage IIIC Primary Peritoneal Cancer AJCC v8, Stage IIIC Uterine Corpus Cancer AJCC v8, Stage IIIC1 Uterine Corpus Cancer AJCC v8, Stage IIIC2 Uterine Corpus Cancer AJCC v8, Stage IV Fallopian Tube Cancer AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Primary Peritoneal Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Stage IV Uterine Corpus Cancer AJCC v8, Stage IVA Fallopian Tube Cancer AJCC v8, Stage IVA Hepatocellular Carcinoma AJCC v8, Stage IVA Ovarian Cancer AJCC v8, Stage IVA Primary Peritoneal Cancer AJCC v8, Stage IVA Uterine Corpus Cancer AJCC v8, Stage IVB Fallopian Tube Cancer AJCC v8, Stage IVB Hepatocellular Carcinoma AJCC v8, Stage IVB Ovarian Cancer AJCC v8, Stage IVB Primary Peritoneal Cancer AJCC v8, Stage IVB Uterine Corpus Cancer AJCC v8View official trial listing → -
Recruiting NCT NCT05096715
Atezolizumab+Bevacizumab+SBRT in Unresectable HCC
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2032-01-31 3 sites Stand-aloneOther conditions: Unresectable Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05139706
Montreal Immune-Related Adverse Events (MIRAE) Study
Sir Mortimer B. Davis - Jewish General Hospital 1000 participants Est. completion 2030-01 1 siteOther conditions: Cancer, Immune System Disorder, Inflammatory Reaction, Autoimmune DiseasesView official trial listing → -
Recruiting NCT NCT05159245
The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs
Not yet reported Helsinki University Central Hospital 250 participants Est. completion 2026-11-25 5 sites Stand-aloneOther conditions: Advanced Cancer, Solid Tumor, Haematological MalignancyView official trial listing → -
Recruiting NCT NCT05168163
Atezolizumab in Combination With a Multi-Kinase Inhibitor for the Treatment of Unresectable, Locally Advanced, or Metastatic Liver Cancer
Not yet reported Academic and Community Cancer Research United 122 participants Est. completion 2026-12-31 16 sites Stand-aloneOther conditions: Locally Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IIIA Hepatocellular Carcinoma AJCC v8, Stage IIIB Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8, Stage IVA Hepatocellular Carcinoma AJCC v8, Stage IVB Hepatocellular Carcinoma AJCC v8, Unresectable Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05263830
Glypican-3 as a Prognostic Factor in Patients With Hepatocellular Carcinoma Treated by Immunotherapy
Assistance Publique - Hôpitaux de Paris 240 participants Est. completion 2029-09-08 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05284539
Efficacy of Platinum-based Chemotherapy Plus Immune Checkpoint Inhibitors for EGFR/ALK/ROS1 Mutant Lung Cancer
Not yet reported Hunan Province Tumor Hospital 760 participants Est. completion 2027-10-10 1 site Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT05287464
International Multicentric Study ARON-1
Hospital of Macerata 1220 participants Est. completion 2027-09-30 1 siteOther conditions: Metastatic Renal Cell Carcinoma (mRCC)View official trial listing → -
Recruiting NCT NCT05312671
Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer
Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 63 participants Est. completion 2029-10 2 sites Stand-aloneOther conditions: Small Cell Neuroendocrine Carcinoma of Bladder, Bladder Cancer, Urothelial Carcinoma BladderView official trial listing → -
Recruiting NCT NCT05317858
Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets
Not yet reported InSightec 96 participants Est. completion 2031-12-01 16 sites Stand-aloneOther conditions: Brain Tumor, Non Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT05332561
Genomics Guided Targeted Post-neoadjuvant Therapy in Patients With Early Breast Cancer (COGNITION-GUIDE)
Not yet reported German Cancer Research Center 240 participants Est. completion 2030-12 9 sites Stand-aloneOther conditions: Early-stage Breast CancerView official trial listing → -
Recruiting NCT NCT05333458
Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, AXIOM Trial
Not yet reported National Cancer Institute (NCI) 27 participants Est. completion 2027-05-01 13 sites Stand-aloneOther conditions: Advanced Alveolar Soft Part Sarcoma, Advanced Soft Tissue Sarcoma, Metastatic Alveolar Soft Part Sarcoma, Refractory Alveolar Soft Part Sarcoma, Unresectable Alveolar Soft Part SarcomaView official trial listing → -
Recruiting NCT NCT05344209
Efficacy and Safety of Anti-PD-1/PD-L1 Treatment +/- UV1 Vaccination in Patients With Non-small Cell Lung Cancer
Not yet reported Vestre Viken Hospital Trust 138 participants Est. completion 2027-07-01 1 site Stand-aloneOther conditions: Oncology, NSCLC Stage IV, NSCLC, Stage IIIView official trial listing → -
Recruiting NCT NCT05423210
Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma Multiforme
Not yet reported Stony Brook University 12 participants Est. completion 2029-08 1 site Stand-aloneOther conditions: Glioblastoma MultiformeView official trial listing → -
Recruiting NCT NCT05434234
A Study of YL201 in Patients With Advanced Solid Tumors
Not yet reported, Not yet reported MediLink Therapeutics (Suzhou) Co., Ltd. 312 participants Est. completion 2027-10-06 45 sites Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Recruiting NCT NCT05440708
A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma
Not yet reported, Not yet reported Tvardi Therapeutics, Incorporated 193 participants Est. completion 2027-03-10 21 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05468359
Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients
Not yet reported, Not yet reported St. Jude Children's Research Hospital 64 participants Est. completion 2037-06 2 sitesOther conditions: Refractory Solid Tumor, Hepatocellular Carcinoma, Malignant Solid Tumor, Pediatric Cancer, Pediatric Solid Tumor, Fibrolamellar CarcinomaView official trial listing → -
Recruiting NCT NCT05483400
Open Label Phase 2 Basket Trial With Atezolizumab and Tiragolumab in Solid Tumors
Not yet reported University Medical Center Groningen 97 participants Est. completion 2027-09 1 site Stand-aloneOther conditions: Head and Neck Neoplasms, MSI-H Cancer, MelanomaView official trial listing → -
Recruiting NCT NCT05488522
SBRT With Atezo/Bev for HCC
Not yet reported Abramson Cancer Center at Penn Medicine 18 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05492123
Nivolumab-ipilimumab and Chemoradiation for Cervical Cancer
Not yet reported Hospital Israelita Albert Einstein 112 participants Est. completion 2028-03-31 14 sitesOther conditions: Uterine Cervical NeoplasmsView official trial listing → -
Recruiting NCT NCT05501665
Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer
Not yet reported, Not yet reported Vanderbilt-Ingram Cancer Center 25 participants Est. completion 2027-02-01 1 site Stand-aloneOther conditions: Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage III Lung CancerView official trial listing → -
Recruiting NCT NCT05516628
Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma
Not yet reported National Cancer Centre, Singapore 30 participants Est. completion 2027-03 6 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05528952
Evaluation of the Interest to Combine a CD4 Th1-inducer Cancer Vaccine Derived From Telomerase and Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma
Not yet reported Centre Hospitalier Universitaire de Besancon 105 participants Est. completion 2030-02-27 14 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05538091
Vismodegib Combined With Atezolizumab in Platinum Resistant Ovarian, Fallopian Tube, and Primary Peritoneal Cancer
Not yet reported Ronald Buckanovich 48 participants Est. completion 2032-09-30 1 site Stand-aloneOther conditions: Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Primary Peritoneal Carcinoma, PARP Inhibitor, Hedgehog InhibitorView official trial listing → -
Recruiting NCT NCT05542407
ONC201 and Atezolizumab in Obesity-Driven Endometrial Cancer
Not yet reported UNC Lineberger Comprehensive Cancer Center 58 participants Est. completion 2028-07-31 1 site Stand-aloneObstructive sleep apnea Other conditions: Endometrial Cancer, Metastasis, Endometrioid Endometrial Cancer, Serous Adenocarcinoma of Endometrium (Diagnosis), Clear Cell Endometrial Carcinoma, Endometrial Endometrioid Adenocarcinoma, Endometrial Mixed Cell AdenocarcinomaView official trial listing → -
Recruiting NCT NCT05549297
Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM)
Not yet reported Immunocore Ltd 540 participants Est. completion 2028-07 82 sitesOther conditions: Advanced MelanomaView official trial listing → -
Recruiting NCT NCT05582499
Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy
Not yet reported Fudan University 716 participants Est. completion 2029-09 1 siteOther conditions: Breast Neoplasm, Breast Cancer, Breast Tumors, Triple-Negative Breast Cancer (TNBC), HER2-positive Breast Cancer, HER2-negative Breast Cancer, Hormone Receptor Positive Tumor, Hormone Receptor Negative Tumor, Early-stage Breast Cancer, Locally Advanced Breast CancerView official trial listing → -
Recruiting NCT NCT05588388
Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases
Not yet reported Kamya Sankar 39 participants Est. completion 2027-12-28 3 sites Stand-aloneOther conditions: Extensive-stage Small-cell Lung Cancer, Liver MetastasesView official trial listing → -
Recruiting NCT NCT05620771
Therasphere® and Systemic Therapy for Patients With Hepatocellular Carcinoma That is High-risk
Not yet reported Northwestern University 200 participants Est. completion 2040-07-01 7 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05652686
A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)
Not yet reported, Not yet reported Phanes Therapeutics 203 participants Est. completion 2028-08 15 sites Stand-aloneOther conditions: Small Cell Lung Cancer (SCLC), Large Cell Neuroendocrine Cancer (LCNEC), Neuroendocrine Prostate Cancer (NEPC), Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC), Neuroendocrine Carcinomas (NEC), Extrapulmonary Neuroendocrine Carcinoma (EP-NEC)View official trial listing → -
Recruiting NCT NCT05690048
Fecal Microbiota Transfer in Liver Cancer to Overcome Resistance to Atezolizumab/Bevacizumab (FLORA)
Not yet reported Michael Dill 48 participants Est. completion 2028-03 7 sites Stand-aloneOther conditions: Immunotherapy, HCC - Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05703971
Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients
Not yet reported, Not yet reported Genprex, Inc. 62 participants Est. completion 2028-06 17 sites Stand-aloneOther conditions: Small Cell Lung Cancer Extensive StageView official trial listing → -
Recruiting NCT NCT05713994
Combined HAIC, TKI/Anti-VEGF and ICIs as Conversion Therapy for Unresectable Hepatocellular Carcinoma
Ze-yang Ding, MD 300 participants Est. completion 2025-12-30 2 sitesOther conditions: Hepatocellular Carcinoma Non-resectableView official trial listing → -
Recruiting NCT NCT05722886
DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol
Not yet reported, Not yet reported Cancer Research UK 825 participants Est. completion 2029-10 27 sites Stand-aloneOther conditions: Haematological Malignancy, Solid TumourView official trial listing → -
Recruiting NCT NCT05733598
Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC
Not yet reported Replimune, Inc. 60 participants Est. completion 2028-07-01 12 sites Stand-aloneOther conditions: Hepatocellular Carcinoma, Biliary Tract CancerView official trial listing → -
Recruiting NCT NCT05751343
Atezolizumab and Bevacizumab Plus TACE-HAIC for Unresectable Advanced HCC: a Phase 2 Clinical Trial
Not yet reported Sun Yat-sen University 55 participants Est. completion 2025-12-30 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05763277
Ate-Bev Early Response Prediction Model in Advanced HCC
Seoul National University Hospital 170 participants Est. completion 2026-12-31 1 siteOther conditions: Hepatocellular Carcinoma, Atezolizumab-bevacizumab, Response EvaluationView official trial listing → -
Recruiting NCT NCT05765084
Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesothelioma
Not yet reported, Not yet reported University Hospital, Antwerp 15 participants Est. completion 2027-10 3 sites Stand-aloneOther conditions: Malignant Pleural MesotheliomaView official trial listing → -
Recruiting NCT NCT05770102
DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition
Not yet reported, Not yet reported Cancer Research UK 30 participants Est. completion 2029-10 27 sites Stand-aloneOther conditions: Malignancy, Malignant Neoplasm, Lymphoproliferative Disorders, Neoplasms by Histologic Type, Neoplasms by Site, Cancer, Colorectal Neoplasms, Endometrial Neoplasms, Melanoma, Solid TumoursView official trial listing → -
Recruiting NCT NCT05797493
Panomic Approach to Immune-Connected Assays in Small Cell Lung Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 100 participants Est. completion 2027-06 1 siteOther conditions: Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT05834413
Clinical Study on the Prevention of Driver Gene Negative Ib-IIIb Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint Inhibitors
Not yet reported Shanghai University of Traditional Chinese Medicine 367 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Lung CancerView official trial listing → -
Recruiting NCT NCT05845450
Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)
Not yet reported Gruppo Oncologico del Nord-Ovest 197 participants Est. completion 2028-05 1 siteOther conditions: Colorectal Cancer, Resectable Colorectal CarcinomaView official trial listing → -
Recruiting NCT NCT05862285
A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study
Not yet reported Hoffmann-La Roche 100 participants Est. completion 2033-03-01 77 sites Stand-aloneOther conditions: CancerView official trial listing → -
Recruiting NCT NCT05870800
Phase II Open-label Trial of Neoadjuvant Immunochemotherapy for Resectable Non-metastatic Colon cancER: NICER
Not yet reported Baylor College of Medicine 28 participants Est. completion 2028-01-01 1 site Stand-aloneOther conditions: Stage I Colon Cancer, Stage II Colon Cancer, Stage III Colon CancerView official trial listing → -
Recruiting NCT NCT05877430
Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer
Not yet reported, Not yet reported CJ Bioscience, Inc. 160 participants Est. completion 2027-10 4 sitesOther conditions: NSCLC, HNSCC, Melanoma, Metastatic Cancer, Advanced Solid Tumor, Advanced CancerView official trial listing → -
Recruiting NCT NCT05907980
A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid Tumors
Not yet reported Chugai Pharmaceutical 209 participants Est. completion 2027-10-31 14 sites Stand-aloneOther conditions: Solid TumorView official trial listing → -
Recruiting NCT NCT05937295
FusionVAC22_01: Fusion Transcript-based Peptide Vaccine Combined with Immune Checkpoint Inhibition
Not yet reported University Hospital Tuebingen 20 participants Est. completion 2027-01 1 site Stand-aloneOther conditions: Fibrolamellar Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT05944237
HTL0039732 in Participants With Advanced Solid Tumours
Not yet reported, Not yet reported Cancer Research UK 150 participants Est. completion 2028-12-31 6 sites Stand-aloneOther conditions: Neoplasms, Prostatic Neoplasms, Castration-Resistant, Stomach Neoplasms, Esophageal Neoplasms, Head and Neck Neoplasms, Colorectal Neoplasms, Pancreatic Neoplasms, Lung Neoplasms, Urinary Bladder Neoplasms, Mesothelioma, Malignant, Uterine Cervical Neoplasms, Kidney Neoplasms, Sarcoma, PheochromocytomasView official trial listing → -
Recruiting NCT NCT05984511
TACE Plus Atezolizumab/Bevacizumab and I-125 Seeds Brachytherapy for HCC With Branch PVTT
Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 234 participants Est. completion 2029-08-01 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma, Hepatic Portal Vein Tumor Invasion, Tumor ThrombusView official trial listing → -
Recruiting NCT NCT05992220
Atezolizumab Plus Bevacizumab Alone or Combined with External Beam Radiotherapy for HCC with Macrovascular Invasion
Not yet reported Asan Medical Center 138 participants Est. completion 2026-03 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma, Hepatocellular Cancer, Hepatocellular Carcinoma Non-resectable, Hepatocellular Carcinoma Stage IV, Liver CancerView official trial listing → -
Recruiting NCT NCT06003621
Tiragolumab and Atezolizumab in Advanced Pan-cancer Patients
Not yet reported Omico 96 participants Est. completion 2028-11-01 13 sites Stand-aloneOther conditions: Solid Tumor, AdultView official trial listing → -
Recruiting NCT NCT06012734
LB-100 (PP2A Inhibitor) and Atezolizumab (PD-L1 Inhibitor) in Metastatic Colorectal Cancer Patients
Not yet reported The Netherlands Cancer Institute 37 participants Est. completion 2028-07 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Recruiting NCT NCT06031233
Evaluating the Safety of Shortened Infusion Times for dIfferent Oncological Immunotherapie
Not yet reported Isala 776 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Oncology, Infusion ReactionView official trial listing → -
Recruiting NCT NCT06043674
Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation
Not yet reported Christine Ryan 70 participants Est. completion 2033-01-15 5 sites Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Richter's TransformationView official trial listing → -
Recruiting NCT NCT06066138
A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing
Not yet reported National Cancer Institute (NCI) 30 participants Est. completion 2028-01-31 1 site Stand-aloneOther conditions: Locally Advanced Alveolar Soft Part Sarcoma, Metastatic Alveolar Soft Part Sarcoma, Locally Advanced Non Small Cell Lung Cancer, Metastatic Non Small Cell Lung Cancer, Locally Advanced Small Cell Lung Cancer, Metastatic Small Cell Lung Cancer, Locally Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma, Locally Advanced Melanoma, Metastatic MelanomaView official trial listing → -
Recruiting NCT NCT06069726
A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial
Not yet reported Duke University 80 participants Est. completion 2028-01-01 4 sites Stand-aloneOther conditions: Recurrent GlioblastomaView official trial listing → -
Recruiting NCT NCT06097962
Safety and Efficacy of NK510 to Treat NSCLC
Not yet reported Base Therapeutics (Shanghai) Co., Ltd. 12 participants Est. completion 2028-07-01 1 site Stand-aloneOther conditions: NSCLCView official trial listing → -
Recruiting NCT NCT06110572
Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation
Not yet reported, Not yet reported Vanderbilt-Ingram Cancer Center 18 participants Est. completion 2028-06-30 1 site Stand-aloneOther conditions: Extensive Stage Lung Small Cell Carcinoma, Stage IV Lung CancerView official trial listing → -
Recruiting NCT NCT06133062
Atezolizumab and Bevacizumab With Proton Radiotherapy for Unresectable Hepatocellular Carcinoma
Not yet reported Chang Gung Memorial Hospital 45 participants Est. completion 2030-09-30 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma Non-resectableView official trial listing → -
Recruiting NCT NCT06135714
Metastasis-directed Therapy for Oligometastases of Breast Cancer
Not yet reported Tokyo Medical and Dental University 146 participants Est. completion 2035-10-31 1 site Stand-aloneOther conditions: Breast Cancer, Oligometastasis, Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT06157827
A Clinical Trial of LBL-024 Combined With Etoposide and Platinum in Patients With Advanced Neuroendocrine Carcinoma
Not yet reported, Not yet reported Nanjing Leads Biolabs Co.,Ltd 178 participants Est. completion 2027-03-28 25 sitesOther conditions: Advanced Neuroendocrine CarcinomaView official trial listing → -
Recruiting NCT NCT06161532
Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...
Not yet reported National Cancer Institute (NCI) 60 participants Est. completion 2028-11-01 1 site Stand-aloneOther conditions: Small Cell Carcinoma of the Bladder, Small Cell Carcinoma of the Urinary Tract, Squamous Cell Carcinoma of the Bladder, Squamous Cell Carcinoma of the Urinary Tract, Primary Adenocarcinoma of the Bladder, Primary Adenocarcinoma of the Urinary Tract, Renal Medullary Carcinoma, Squamous Cell Carcinoma of the PenisView official trial listing → -
Recruiting NCT NCT06179069
A Study of ZL-1310 in Subjects With Small Cell Lung Cancer
Not yet reported Zai Lab (Shanghai) Co., Ltd. 339 participants Est. completion 2027-07-31 41 sites Stand-aloneOther conditions: SCLCView official trial listing → -
Recruiting NCT NCT06182072
ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)
Not yet reported ProDa BioTech, LLC 46 participants Est. completion 2028-06-30 1 site Stand-aloneOther conditions: Pancreatic Ductal Adenocarcinoma (PDAC)View official trial listing → -
Recruiting NCT NCT06254248
Safety of Atezolizumab-Bevacizumab in Liver Transplanted Patients With Advanced Hepatocellular Carcinoma
Not yet reported Assistance Publique - Hôpitaux de Paris 50 participants Est. completion 2030-01-01 10 sites Stand-aloneOther conditions: Liver Transplant, Hepatocellular Carcinoma Recurrent, Systemic TreatmentView official trial listing → -
Recruiting NCT NCT06254911
Pre-operative Atezolizumab in Patients With Resectable, Human Papillomavirus Related Oropharyngeal Carcinoma
Not yet reported Emory University 20 participants Est. completion 2026-12-16 1 site Stand-aloneOther conditions: Oropharynx Cancer, Stage IView official trial listing → -
Recruiting NCT NCT06287775
Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 45 participants Est. completion 2029-07-25 43 sites Stand-aloneOther conditions: Extensive Stage Lung Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8View official trial listing → -
Recruiting NCT NCT06294548
A Study of Valemetostat Tosylate (DS-3201b) With Atezolizumab and Bevacizumab in HCC
Not yet reported, Not yet reported University of Alabama at Birmingham 45 participants Est. completion 2028-08-28 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT06302426
Trial of INI-4001 in Patients With Advanced Solid Tumours
Not yet reported Inimmune Corporation 50 participants Est. completion 2027-03-30 3 sites Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Recruiting NCT NCT06323382
Locoregional Therapy Combined With Bevacizumab and PD1/L1 Inhibitor in Advanced Hepatocellular Carcinoma
Sun Yat-sen University 240 participants Est. completion 2025-12-30 1 siteOther conditions: Advanced Hepatocellular Carcinoma, Anti-PD1/PDL1 Antibody, BevacizumabView official trial listing → -
Recruiting NCT NCT06332755
Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC
Not yet reported LG Chem 76 participants Est. completion 2028-03 1 site Stand-aloneOther conditions: Non-small Cell Lung Cancer(NSCLC), Head and Neck Squamous Cell Carcinoma(HNSCC), Renal Cell Carcinoma(RCC), Urothelial Carcinoma, Malignant MelanomaView official trial listing → -
Recruiting NCT NCT06339424
Atezolizumab and Bevacizumab With Photon Radiotherapy for Unresectable Hepatocellular Carcinoma
Not yet reported Chang Gung Memorial Hospital 45 participants Est. completion 2031-03-30 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT06342037
NOvel Immunotherapy Strategies for Advanced Triple Negative Breast Cancer (TNBC) Patients: TONIC-3 Trial
Not yet reported The Netherlands Cancer Institute 60 participants Est. completion 2030-04-01 1 site Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT06362252
A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)
Not yet reported, Not yet reported Daiichi Sankyo 123 participants Est. completion 2028-02-20 58 sites Stand-aloneOther conditions: Extensive Stage-small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT06422403
A Value-Driven Study on Reducing Immune Checkpoint Inhibitor Dosing Frequency in Advanced Cancers
Not yet reported National University Hospital, Singapore 360 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Carcinoma, Hepatocellular, Gastric Adenocarcinoma, GastroEsophageal Cancer, Oesophageal Cancer, Non-small Cell Lung Cancer, Head and Neck Squamous Cell CarcinomaView official trial listing → -
Recruiting NCT NCT06429696
PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer
Not yet reported Nanfang Hospital, Southern Medical University 40 participants Est. completion 2026-04-30 1 site Stand-aloneOther conditions: Small Cell Lung Cancer Extensive StageView official trial listing → -
Recruiting NCT NCT06439485
Phase I/II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion
Not yet reported, Not yet reported M.D. Anderson Cancer Center 25 participants Est. completion 2030-02-22 1 site Stand-aloneOther conditions: Advanced Cholangiocarcinoma, FGFR2 FusionView official trial listing → -
Recruiting NCT NCT06444815
A Study of VET3-TGI in Patients With Solid Tumors
Not yet reported KaliVir Immunotherapeutics 60 participants Est. completion 2027-12-31 7 sites Stand-aloneObstructive sleep apnea Other conditions: Solid Tumor, Adult, Head and Neck Squamous Cell Carcinoma, Cervical Cancer, Kidney Cancer, Renal Cell Carcinoma, Melanoma Stage IV, Merkel Cell Carcinoma of Skin, Mesothelioma, Non-small Cell Lung Cancer, Cutaneous Squamous Cell Carcinoma (CSCC), Urothelial Carcinoma Bladder, Squamous Cell CarcinomaView official trial listing → -
Recruiting NCT NCT06463665
Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer
Not yet reported Genelux Corporation 142 participants Est. completion 2029-07 15 sites Stand-aloneOther conditions: Advanced Non-squamous Non-small-cell Lung Cancer, Advanced Squamous Non-Small Cell Lung Carcinoma, Metastatic Non-squamous Non Small Cell Lung Cancer, Metastatic Squamous Non-Small Cell Lung Carcinoma, Non-small Cell Lung Cancer, Non-small Cell Lung Cancer Stage III, Non-small Cell Lung Cancer Stage IV, Non-small Cell Lung Cancer RecurrentView official trial listing → -
Recruiting NCT NCT06475209
Adebrelimab + Apatinib in SCLC Maintenance Therapy
Not yet reported Tang-Du Hospital 60 participants Est. completion 2026-12-20 1 site Stand-aloneOther conditions: SCLCView official trial listing → -
Recruiting NCT NCT06478693
A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCC
Not yet reported Myeloid Therapeutics 70 participants Est. completion 2028-05-31 9 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT06492954
Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma
Not yet reported Emory University 12 participants Est. completion 2027-06 1 site Stand-aloneObstructive sleep apneaView official trial listing → -
Recruiting NCT NCT06529081
Radiotherapy Strategies for Use in Combined Treatment of Small-cell Lung Cancer
Not yet reported Copernicus Memorial Hospital 165 participants Est. completion 2029-12-31 2 sitesOther conditions: Small Cell Lung CarcinomaView official trial listing → -
Recruiting NCT NCT06551142
A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)
Not yet reported GlaxoSmithKline 845 participants Est. completion 2029-06-08 67 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Recruiting NCT NCT06551272
Microbiota Modification for Immuno-oncology in Hepatocellular Carcinoma
Not yet reported Center Eugene Marquis 34 participants Est. completion 2026-12-12 6 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT06555133
Y-90, Capecitabine, and Atezolizumab for Oligometastatic CRC
Not yet reported Brown University 18 participants Est. completion 2029-09-01 1 site Stand-aloneOther conditions: Colorectal Carcinoma Metastatic in the LiverView official trial listing → -
Recruiting NCT NCT06562920
Adebrelimab Combined With Chemotherapy and Concurrent SBRT for Neoadjuvant Treatment of Limited-stage Small Cell Lung Cancer
Not yet reported Zhejiang Cancer Hospital 20 participants Est. completion 2028-07-31 1 siteOther conditions: Efficacy and Safety of Neoadjuvant Immunotherapy for Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT06595108
Atezolizumab and BEvacizumab With STereotactic Body Radiotherapy for Advanced Hepatocellular Carcinoma
Not yet reported Yonsei University 33 participants Est. completion 2028-03-27 1 site Stand-aloneOther conditions: Advanced Hepatocellular Carcinoma, Chemotherapy, Stereotactic Body RadiotherapyView official trial listing → -
Recruiting NCT NCT06605664
Hyperpolarized 13C-MRI in Patients With Hepatocellular Carcinoma Undergoing Radiotherapy, Atezolizumab, and Bevacizumab
Not yet reported Chang Gung Memorial Hospital 45 participants Est. completion 2031-09-30 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT06609863
dTACE-HAIC Combined With Bevacizumab and Atezolizumab for Huge Hepatocellular Carcinoma
Not yet reported Sun Yat-sen University 27 participants Est. completion 2026-06-30 1 site Stand-aloneOther conditions: Advanced Hepatocellular Carcinoma, Atezolizumab, Bevacizumab, ChemotherapyView official trial listing → -
Recruiting NCT NCT06622486
First-in-human Trial of EGL-001 in Patients with Selected Advanced And/or Metastatic Solid Tumors
Not yet reported, Not yet reported Egle Therapeutics 50 participants Est. completion 2027-01-23 8 sitesOther conditions: Solid Tumor, AdultView official trial listing → -
Recruiting NCT NCT06646276
A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).
Not yet reported Bristol-Myers Squibb 530 participants Est. completion 2031-07-14 183 sitesOther conditions: Extensive-Stage Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT06663098
Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC).
Not yet reported Gruppo Oncologico Italiano di Ricerca Clinica 142 participants Est. completion 2029-06-01 25 sites Stand-aloneOther conditions: Extensive Stage Small Cell Lung Cancer (ES-SCLC)View official trial listing → -
Recruiting NCT NCT06690840
Atezolizumab and Chemotherapy Treatment as T-cell Activators in Metastatic Triple Negative Breast Cancer Patients
Not yet reported European Institute of Oncology 45 participants Est. completion 2027-02-15 5 sites Stand-aloneOther conditions: Triple Negative Breast CancerView official trial listing → -
Recruiting NCT NCT06695026
A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 in Combination With Valganciclovir (VGCV) and Atezolizumab/Bevacizumab in Subjects With Hepatocellular Carcinoma
Not yet reported, Not yet reported Rznomics, Inc. 45 participants Est. completion 2027-10 9 sites Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT06702566
The Effect of Serum Ferritin in irAE
Not yet reported Tianjin Medical University Cancer Institute and Hospital 1500 participants Est. completion 2027-07-01 1 site Stand-aloneOther conditions: Immune-related Adverse Event, Malignant Solid Tumors, Acute Leukemia, Serum FerritinView official trial listing → -
Recruiting NCT NCT06712355
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
Not yet reported BioNTech SE 621 participants Est. completion 2029-07 225 sitesOther conditions: Extensive-stage Small-cell Lung CancerView official trial listing → -
Recruiting NCT NCT06717243
Genomic and Methylation Markers in SCLC and LCNEC for Chemo-Immunotherapy Resistance Prediction (STRATUS)
Oncology Center of Biochemical Education And Research 111 participants Est. completion 2028-12-01 2 sitesOther conditions: Small Cell Lung Cancer, Large Cell Neuroendocrine (NE) Tumors, Treatment Failure, Biomarkers / Blood, Biomarkers, ImmunotherapyView official trial listing → -
Recruiting NCT NCT06725121
Using Radiotherapy and Immunotherapy to Treat Advanced Liver Cancer Before Transplant
Not yet reported, Not yet reported University Health Network, Toronto 48 participants Est. completion 2034-06 2 sitesOther conditions: Hepatocellular Carcinoma (HCC), Macrovascular Invasion, Liver Transplant Surgery, DownstagingView official trial listing → -
Recruiting NCT NCT06731270
Diclofenac for the Treatment of Patients With Metastatic Non-small Cell Lung Cancer on Single Agent Immunotherapy
Not yet reported Emory University 20 participants Est. completion 2028-01-01 2 sites Stand-aloneOther conditions: Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8View official trial listing → -
Recruiting NCT NCT06733038
FOLFOXIRI Plus Bevacizumab With or Without Atezolizumab as 1st Line Treatment of pMMR and IS IC-High Metastatic Colorectal Cancer Patients.
Not yet reported Gruppo Oncologico del Nord-Ovest 238 participants Est. completion 2029-04-01 24 sites Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Recruiting NCT NCT06768307
Assessment of Adebelizumab Combined With Chemotherapy in Concurrent Radiotherapy Versus Sequential Radiotherapy as First-Line Treatment for Extensive-Stage Small Cell Lung Cancer
Not yet reported Peking University Cancer Hospital & Institute 60 participants Est. completion 2028-01-31 1 site Stand-aloneOther conditions: SCLC, Extensive Stage, Immunotherapy, Chemotherapy, RadiotherapyView official trial listing → -
Recruiting NCT NCT06771518
Association of Thoraco-mediastinal Radiotherapy With Maintenance Immunotherapy Treatment With Atezolizumab
Not yet reported Regina Elena Cancer Institute 37 participants Est. completion 2026-12-15 1 site Stand-aloneOther conditions: Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT06780826
A Study on the Efficacy of Atezolizumab Combined with Chemotherapy
Shanghai Pulmonary Hospital, Shanghai, China 1430 participants Est. completion 2025-09-30 1 siteOther conditions: Lung Cancer, Small CellView official trial listing → -
Recruiting NCT NCT06789757
The Study of Atezolizumab, Bevacizumab and Memantine in Patients With Hepatocellular Carcinoma (HCC)
Not yet reported Inova Health Care Services 19 participants Est. completion 2030-01-27 2 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT06793553
Induction Therapy of PTX+BV Followed by Atezolizumab+Nab-PTX for PD-L1+ TNBC
Not yet reported Japan Breast Cancer Research Group 106 participants Est. completion 2028-09-30 1 site Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Recruiting NCT NCT06806579
Atezolizumab-bevacizumab and Other Immunotherapies: Real-life Experience for Treatment of Hepatocellular Carcinoma
IRCCS Azienda Ospedaliero-Universitaria di Bologna 1000 participants Est. completion 2031-10-31 24 sitesOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT06807632
A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 24 participants Est. completion 2027-01 7 sites Stand-aloneOther conditions: Extensive-stage Small-cell Lung CancerView official trial listing → -
Recruiting NCT NCT06819566
Prophylactic Endoscopic Variceal Ligation in Patients With High-risk Esophageal Varices Receiving Atezo/Bev for HCC
Not yet reported Asan Medical Center 44 participants Est. completion 2029-03-31 1 siteOther conditions: Hepatocellular Carcinoma, Esophageal Varix, Bleeding Esophageal VaricesView official trial listing → -
Recruiting NCT NCT06823375
SBRT With Immunotherapy and Atezo-Bev in HCC With Major Portal Vein Thrombosis
Not yet reported Chinese University of Hong Kong 40 participants Est. completion 2028-07-31 2 sites Stand-aloneOther conditions: HCCView official trial listing → -
Recruiting NCT NCT06830694
Clinical Trial for Safety and Effectiveness Evaluation of Tarlatamab (AMG757) With Etoposide, Carboplatin and Atezolizumab in Transformed Small Cell Lung Cancer Patients From Adenocarcinoma After EGFR TKI Treatment
Not yet reported Sehhoon Park 50 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: Small Cell Carcinoma of LungView official trial listing → -
Recruiting NCT NCT06840782
First-line Immunotherapy-based Standard of Care and Local Ablative Treatments for Oligometastatic Non-small Cell Lung Cancer Patients.
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 124 participants Est. completion 2030-02 3 sites Stand-aloneOther conditions: Oligometastatic Non-small Cell Lung Cancer (NSCLC)View official trial listing → -
Recruiting NCT NCT06841172
Continuation of First-line Therapy With Radiotherapy Versus Early Switch to Second-line Therapy in Oligoprogressive HCC
Not yet reported Shandong Cancer Hospital and Institute 132 participants Est. completion 2028-07-01 1 site Stand-aloneOther conditions: OligoProgressive Metastatic Disease, Hepatocellular Carcinoma (HCC), Radiotherapy, Systemic TherapyView official trial listing → -
Recruiting NCT NCT06869239
Prediction of Response to PD-L1 Inhibitor After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer Using Multi-omics-based Liquid Biopsy
Peking University Cancer Hospital & Institute 65 participants Est. completion 2028-01-03 1 siteOther conditions: Limited-stage Small Cell Lung Cancer (LS-SCLC)View official trial listing → -
Recruiting NCT NCT06908993
Tepotinib vs Standard Treatment in Patients With Advanced MET Exon 14 Mutated Non-Small Cell Lung Cancer Previously Treated
Not yet reported Intergroupe Francophone de Cancerologie Thoracique 133 participants Est. completion 2028-07-15 29 sitesOther conditions: Advanced Non Small Cell Lung Cancer, MET Exon 14 MutationView official trial listing → -
Recruiting NCT NCT06921785
Phase III Study of Rilvegostomig in Combination With Bevacizumab With or Without Tremelimumab as First-line Treatment of Hepatocellular Carcinoma
Not yet reported AstraZeneca 1220 participants Est. completion 2030-03-15 226 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT06926179
Safety, Efficacy, and Survival Outcomes of Neoadjuvant/Induction Immunotherapy in Surgical and Radiotherapeutic Management of Non-Small Cell Lung Cancer
Peking University Cancer Hospital & Institute 500 participants Est. completion 2028-03-31 4 sitesOther conditions: Lung Cancer (NSCLC), Neoadjuvant Immunotherapy, Radiotherapy, Lung SurgeryView official trial listing → -
Recruiting NCT NCT06961526
Esophageal Varices Prophylaxis in Hepatocellular Carcinoma Treated With Atezolizumab and Bevacizumab
Not yet reported Tanta University 110 participants Est. completion 2026-07 1 siteOther conditions: Esophageal and/or Gastric Varices, Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT06988592
GemCis Plus PD-1/PD-L1 Inhibitor in Advanced Biliary Tract Cancer: Efficacy and Immune Microenvironment (BTC-IM-1)
Fudan University 100 participants Est. completion 2027-12-30 1 siteOther conditions: Advanced Biliary Tract CancerView official trial listing → -
Recruiting NCT NCT07010497
A Prospective Study to Evaluate the Safety and Efficacy of the Combination Therapy of Irpagratinib, Atezolizumab, and Bevacizumab in Patients With Hepatocellular Carcinoma
Not yet reported Asan Medical Center 33 participants Est. completion 2029-03-31 3 sites Stand-aloneOther conditions: Carcinoma, HepatocellularView official trial listing → -
Recruiting NCT NCT07011004
A Study of Natural Killer Cells in Combination With Atezolizumab in People With Acute Myelogenous Leukemia
Not yet reported Memorial Sloan Kettering Cancer Center 18 participants Est. completion 2028-05 7 sites Stand-aloneOther conditions: Acute Myeloid Leukemia Refractory, Acute Myeloid Leukemia, in RelapseView official trial listing → -
Recruiting NCT NCT07018947
Study to Evaluate the Efficacy and Safety of Atezolizumab and Bevacizumab as Neoadjuvant Plus Adjuvant Treatment in HCC
Not yet reported Fundacion Clinic per a la Recerca Biomédica 90 participants Est. completion 2031-06 12 sites Stand-aloneOther conditions: Resectable Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07021911
Concomitant Radiotherapy and New Drugs in Metastatic Breast Cancer
Fondazione Policlinico Universitario Campus Bio-Medico 300 participants Est. completion 2029-05-17 1 siteOther conditions: Breast Cancer, Radiotherapy; ComplicationsView official trial listing → -
Recruiting NCT NCT07049848
SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma
Not yet reported M.D. Anderson Cancer Center 50 participants Est. completion 2030-01-01 1 site Stand-aloneOther conditions: Soft Tissue SarcomaView official trial listing → -
Recruiting NCT NCT07059494
Atezolizumab and Bevacizumab in Combination With Y^90 Radioembolization in HCC for Liver Transplant
Not yet reported Icahn School of Medicine at Mount Sinai 40 participants Est. completion 2028-08-01 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07113691
Iadademstat + SBRT With Atezo in ES-SCLC
Not yet reported Yale University 15 participants Est. completion 2030-01 1 site Stand-aloneOther conditions: Extensive Stage Small Cell Lung Cancer (ES-SCLC)View official trial listing → -
Recruiting NCT NCT07130032
Efficacy And Safety Of Anti-PD-1/PD-L1 Antibodies In Combination With Bevacizumab And Metronomic Cyclophosphamide In Patients With Non-Small Cell Lung Cancer And Cutaneous Melanoma Previously Treated With Immune Checkpoint Blockade
Not yet reported EuroCityClinic LLC 90 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Metastatic Non-small Cell Lung Cancer (NSCLC), Metastatic Cutaneous MelanomaView official trial listing → -
Recruiting NCT NCT07153445
Neoadjuvant Treatment With Atezolizumab and Atezolizumab as Maintenance for the Treatment of Stage III Non Small-Cell Lung Cancer (NSCLC)
Not yet reported Fundación GECP 97 participants Est. completion 2035-05-02 21 sites Stand-aloneOther conditions: Non Small Cell Lung Cancer, Stage IIIA Lung Cancer, Stage IIIB Lung CancerView official trial listing → -
Recruiting NCT NCT07155174
A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer
Not yet reported AbbVie 180 participants Est. completion 2031-09 69 sites Stand-aloneOther conditions: Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT07157969
ICIs and Anti-VEGF Antibody/TKIs With or Without Interventional Therapy for Advanced HCC
Not yet reported Peking Union Medical College Hospital 300 participants Est. completion 2027-06-30 1 site Stand-aloneOther conditions: HCC - Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07166406
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
Not yet reported NRG Oncology 226 participants Est. completion 2034-03-10 139 sites Stand-aloneOther conditions: Advanced Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8View official trial listing → -
Recruiting NCT NCT07190833
A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients (South Korea)
Not yet reported Bionoxx Inc. 27 participants Est. completion 2030-12 2 sites Stand-aloneOther conditions: Treatment-Refractory Solid TumorsView official trial listing → -
Recruiting NCT NCT07192185
Systemic Chemotherapy With FOLFOX Plus Atezolizumab & Bevacizumab for Patients With Advanced HCC Who Previously Received Atezolizumab & Bevacizumab
Not yet reported Sun Yat-sen University 30 participants Est. completion 2027-03-01 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT07195695
Beamion LUNG-3: Adjuvant Zongertinib vs Standard Treatment in People With Completely Resected Stage II-IIIB NSCLC Harboring Activating HER2 TKD Mutations
Not yet reported Boehringer Ingelheim 400 participants Est. completion 2036-09-02 202 sitesOther conditions: Non-small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT07224971
Impact of Circadian Rhythm on Immunotherapy
Not yet reported Liza Villaruz, MD 350 participants Est. completion 2030-05-01 1 site Stand-aloneOther conditions: Advanced/Metastatic NSCLCView official trial listing → -
Recruiting NCT NCT07226999
Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer
Not yet reported, Not yet reported Pfizer 550 participants Est. completion 2034-03-11 82 sitesOther conditions: Small Cell Lung Cancer (SCLC)View official trial listing → -
Recruiting NCT NCT07227597
A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)
Not yet reported, Not yet reported Merck Sharp & Dohme LLC 170 participants Est. completion 2030-12-30 57 sites Stand-aloneOther conditions: Small Cell Lung Cancer Extensive StageView official trial listing → -
Recruiting NCT NCT07235293
A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.
Not yet reported Kahr Bio Australia Pty Ltd 90 participants Est. completion 2027-04-30 18 sites Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Recruiting NCT NCT07239245
Study to Evaluate the Efficacy and Safety of Neo-Adjuvant TACE and Atezolizumab Plus Bevacizumab Therapy for High-Risk Recurrent Hepatocellular Carcinamo
Not yet reported Cancer Institute and Hospital, Chinese Academy of Medical Sciences 30 participants Est. completion 2030-11-10 4 sites Stand-aloneOther conditions: Resectable Hepatocellular Carcinoma With High Risk of RecurrenceView official trial listing → -
Recruiting NCT NCT07246668
A Phase II Single-Arm Clinical Study to Evaluate the Efficacy and Safety of Carbon Ion Radiotherapy With Atezolizumab and Bevacizumab Combination Therapy in Patients With Advanced Hepatocellular Carcinoma
Not yet reported Yonsei University 52 participants Est. completion 2028-03 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma, Liver Neoplasms, Carcinoma, HepatocellularView official trial listing → -
Recruiting NCT NCT07263438
Efficacy of the Combination of Trimipramine and Atezolizumab With Bevacizumab in Patients With Recurrent Glioblastoma: a Phase 2 Trial
Not yet reported Centre Hospitalier Universitaire Vaudois 59 participants Est. completion 2030-12-31 7 sites Stand-aloneOther conditions: Glioblastoma, Recurrence TumorView official trial listing → -
Recruiting NCT NCT07276100
Fecal Microbiota Transplantation to RESCUE Patients With Unresectable Hcc Progressors to First Line Therapy With AtezolizUmaB and Bevacizumab
Not yet reported IRCCS Azienda Ospedaliero-Universitaria di Bologna 15 participants Est. completion 2029-01-01 1 site Stand-aloneOther conditions: Hepato Cellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT07279402
TRIMPACT: Real-World First-Line Atezolizumab Use in Stage IV NSCLC With PD-L1 ≥50%
Antalya Training and Research Hospital 150 participants Est. completion 2027-10-01 25 sitesOther conditions: NSCLC Stage IV, PD-L1 Gene Mutation, Atezolizumab, Real World StudyView official trial listing → -
Recruiting NCT NCT07284121
A Study to Evaluate Patient-Reported Satisfaction, Effectiveness, and Safety of Atezolizumab in Participants Treated in Routine Clinical Practice
Hoffmann-La Roche 700 participants Est. completion 2028-12-31 92 sitesOther conditions: Lung Cancer, Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07285850
The Efficacy of Sequential Treatment With Bevacizumab Combined With Atezolizumab in Advanced Liver Cancer With MASLD
Not yet reported, Not yet reported Eastern Hepatobiliary Surgery Hospital 20 participants Est. completion 2026-08-30 1 site Stand-aloneOther conditions: HCC - Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07293468
Comparison of SBRT and SIRT With Combination IO for Locally-advanced, Unresectable HCCs (BIIRTH)
Not yet reported, Not yet reported Tuen Mun Hospital 106 participants Est. completion 2034-12-31 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT07317414
β-alanine in the Treatment of Advanced Hepatocellular Carcinoma
Not yet reported Peking Union Medical College Hospital 158 participants Est. completion 2030-12-05 3 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07322341
SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung Cancer
Not yet reported University of Washington 32 participants Est. completion 2031-11-01 1 site Stand-aloneOther conditions: Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8View official trial listing → -
Recruiting NCT NCT07339059
Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer
Not yet reported Bindu R Potugari 35 participants Est. completion 2029-12-01 1 site Stand-aloneOther conditions: Small Cell Lung Cancer ( SCLC ), Extensive Stage Small Cell Lung Cancer (ES-SCLC)View official trial listing → -
Recruiting NCT NCT07365930
NIS on the Benefits of TIPS in Patients With HCC Receiving Atezo+Bev in 1st-Line Therapy
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 350 participants Est. completion 2031-12-17 1 siteOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Recruiting NCT NCT07381634
The Safety and Efficacy of Ondansetron in Reducing Immune Checkpoint Inhibitor-Related Toxicities
Not yet reported First Affiliated Hospital of Wenzhou Medical University 134 participants Est. completion 2027-06-20 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC), IrAEView official trial listing → -
Recruiting NCT NCT07385001
A Prospective, Multicenter, Phase Ib/II Trial of Ivonescimab (AK112) Combined With Albumin-Paclitaxel and Cisplatin as Neoadjuvant Therapy for ESCC
Not yet reported, Not yet reported Tang-Du Hospital 45 participants Est. completion 2028-01-28 1 siteOther conditions: Esophageal Squamous Cell Carcinoma, Ivonescimab, NeoadjuvantView official trial listing → -
Recruiting NCT NCT07388524
Testing the Impact of an Anti-Cancer Drug, Atezolizumab, After Surgery to Prevent Early Stage Non-small Cell Lung Cancer From Returning, AASI-NSCLC Trial
Not yet reported National Cancer Institute (NCI) 336 participants Est. completion 2032-09-30 106 sites Stand-aloneOther conditions: Lung Non-Small Cell CarcinomaView official trial listing → -
Recruiting NCT NCT07407933
A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors
Not yet reported, Not yet reported MediLink Therapeutics (Suzhou) Co., Ltd. 118 participants Est. completion 2029-02 38 sites Stand-aloneOther conditions: Thoracic Neoplasms, Lung Diseases, Small Cell Lung CarcinomaView official trial listing → -
Recruiting NCT NCT07472517
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemoimmunotherapy
Not yet reported Boehringer Ingelheim 670 participants Est. completion 2029-07-30 245 sites Stand-aloneOther conditions: Small Cell Lung Cancer (SCLC), Extensive-stage Small Cell Lung Cancer (ES-SCLC)View official trial listing → -
Recruiting NCT NCT07495735
Intelligence System for Predicting Atezolizumab-Bevacizumab Response and Clinical Outcomes in Unresectable Hepatocellular Carcinoma
First Affiliated Hospital of Wenzhou Medical University 400 participants Est. completion 2026-12-30 1 siteOther conditions: HCC - Hepatocellular Carcinoma, Atezolizumab and Bevacizumab in Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07538128
Evaluating Safety, Tolerability, and Preliminary Efficacy of YSCH-01 Monotherapy and in Combination With Atezolizumab for Recurrent Glioblastoma
Not yet reported Huashan Hospital 10 participants Est. completion 2027-02-28 1 site Stand-aloneOther conditions: Recurrent GlioblastomaView official trial listing → -
Recruiting NCT NCT07545954
DSP-0390 in Combination With Atezolizumab for Small Cell Lung Cancer
Not yet reported Washington University School of Medicine 20 participants Est. completion 2030-02-28 1 site Stand-aloneOther conditions: Small-cell Lung Cancer, Small Cell Lung Cancer Extensive StageView official trial listing → -
Recruiting NCT NCT07610551
Efficacy and Safety of SIRT-Y90 in Combination With Atezo + Bev for Unresectable Hepatocellular Carcinoma
Air Force Military Medical University, China 50 participants Est. completion 2026-12-31 1 siteOther conditions: HCC - Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07625644
BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)
Not yet reported SystImmune Inc. 550 participants Est. completion 2031-06 62 sites Stand-aloneOther conditions: Small Cell Lung Cancer Extensive Stage, Small-cell Lung Cancer, Small Cell Carcinoma, Sclc, SCLC,Extensive Stage, Lung Cancer, Lung Cancer Metastatic, Lung Cancer Stage IVView official trial listing → -
Recruiting NCT NCT07654400
A Study of BL-M14D1 in Combination With Atezolizumab in Patients With Extensive-stage Small Cell Lung Cancer
Not yet reported Sichuan Baili Pharmaceutical Co., Ltd. 36 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Extensive-stage Small-cell Lung CancerView official trial listing → -
Recruiting NCT NCT07759856
NK Cells Plus ICI for SCLC Maintenance
Not yet reported Tianjin First Central Hospital 42 participants Est. completion 2029-08 1 site Stand-aloneOther conditions: Small Cell Lung CancerView official trial listing → -
Recruiting NCT NCT07770100
Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy (SBRT) for Stage IV Cancers (COINSSS IV)
Not yet reported Mark Bernard 35 participants Est. completion 2040-02-28 1 site Stand-aloneOther conditions: Head and Neck Cancer, Non-Small Cell Lung Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer (GC)View official trial listing → -
Recruiting NCT NCT07793695
Oral Zinc Supplementation Combined With Targeted Immunotherapy for Unresectable or Advanced Hepatocellular Carcinoma
Not yet reported Anhui Provincial Hospital 60 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07814014
Real-world Insight Into Systemic Therapies for HCC: Single-center Study
Mansoura University 1000 participants Est. completion 2027-12-15 1 siteOther conditions: HCC - Hepatocellular CarcinomaView official trial listing → -
Recruiting NCT NCT07856212
Maintenance Therapy in Metastatic Gastric Cancer: A Multicenter Retrospective Study in Colombia
Fundación Santa Fe de Bogota 150 participants Est. completion 2027-03-01 4 sitesOther conditions: Stomach Neoplasms, Gastric Adenocarcinoma, Metastatic Gastric CancerView official trial listing → -
Recruiting NCT NCT07884877
PULSAR Radiotherapy Combined With Immunotherapy for High-Risk Advanced Liver Cancer
Not yet reported Samsung Medical Center 38 participants Est. completion 2030-10 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC), Radiotherapy-Induced Immune Priming, ImmunotherapyView official trial listing → -
Completed NCT NCT00729664
Multiple Ascending Dose (MDX1105-01)
Not yet reported Bristol-Myers Squibb 281 participants Est. completion 2015-07 11 sitesOther conditions: Cancer, Multiple IndicationsView official trial listing → -
Active, not recruiting NCT NCT00781612
A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies
Not yet reported Genentech, Inc. 378 participants Est. completion 2027-06-30 179 sites Stand-aloneOther conditions: Neoplasm MetastasisView official trial listing → -
Completed NCT NCT01375842
A Study of Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PDL1] Antibody) to Evaluate Safety, Tolerability and Pharmacokinetics in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Genentech, Inc. 661 participants Est. completion 2018-09-30 21 sites Stand-aloneOther conditions: Tumors, Hematologic MalignanciesView official trial listing → -
Withdrawn NCT NCT01455103
Phase 1 Biomarker Study of Anti-PDL-1 in Advanced Melanoma
Not yet reported Bristol-Myers Squibb Est. completion 2013-11Other conditions: Stage III or IV MelanomaView official trial listing → -
Completed NCT NCT01633970
A Study of Atezolizumab Administered in Combination With Bevacizumab and/or With Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Genentech, Inc. 240 participants Est. completion 2020-02-26 11 sites Stand-aloneOther conditions: CancerView official trial listing → -
Completed NCT NCT01656642
A Phase 1b Study of Atezolizumab in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participants With BRAFV600-Mutation Positive Metastatic Melanoma
Not yet reported Genentech, Inc. 67 participants Est. completion 2020-03-25 8 sites Stand-aloneOther conditions: Malignant MelanomaView official trial listing → -
Completed NCT NCT01688206
A Study of Vanucizumab (RO5520985) Alone or in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Hoffmann-La Roche 132 participants Est. completion 2018-03-12 14 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Suspended NCT NCT01810913
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 613 participants Est. completion 2027-01-01 342 sites Stand-aloneOther conditions: Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7, Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7, Stage IV Laryngeal Squamous Cell Carcinoma AJCC v7, Stage IV Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7, Stage IV Oropharyngeal Squamous Cell Carcinoma AJCC v7View official trial listing → -
Completed NCT NCT01846416
A Study of Atezolizumab in Participants With Programmed Death-Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) [FIR]
Not yet reported Genentech, Inc. 138 participants Est. completion 2017-12-18 31 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT01898117
Triple-B Study;Carboplatin-cyclophosphamide Versus Paclitaxel With or Without Atezolizumab as First-line Treatment in Advanced Triple Negative Breast Cancer
Not yet reported The Netherlands Cancer Institute 304 participants Est. completion 2030-12 49 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT01903993
A Randomized Phase 2 Study of Atezolizumab (an Engineered Anti-PDL1 Antibody) Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum Therapy - "POPLAR"
Not yet reported Hoffmann-La Roche 287 participants Est. completion 2018-09-06 65 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT01984242
A Study of Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) as Monotherapy or in Combination With Bevacizumab (Avastin®) Compared to Sunitinib (Sutent®) in Participants With Untreated Advanced Renal Cell Carcinoma
Not yet reported Hoffmann-La Roche 305 participants Est. completion 2019-01-08 45 sites Stand-aloneOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT01988896
Study of Atezolizumab in Combination With Cobimetinib in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Hoffmann-La Roche 153 participants Est. completion 2019-11-04 21 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT02008227
A Study of Atezolizumab Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum-Containing Therapy
Not yet reported Hoffmann-La Roche 1225 participants Est. completion 2019-01-09 208 sites Stand-aloneOther conditions: Non-Squamous Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02013219
A Phase 1b Study of Atezolizumab in Combination With Erlotinib or Alectinib in Participants With Non-Small Cell Lung Cancer (NSCLC)
Not yet reported Hoffmann-La Roche 52 participants Est. completion 2020-02-05 17 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02031458
A Study of Atezolizumab in Participants With Programmed Death - Ligand 1 (PD-L1) Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 667 participants Est. completion 2019-01-11 110 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02091141
My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors
Not yet reported Genentech, Inc. 673 participants Est. completion 2023-05-24 60 sites Stand-aloneOther conditions: Neoplasms, Solid Tumors, Biliary Cancer, Salivary Cancer, Bladder CancerView official trial listing → -
Completed NCT NCT02108652
A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 2)
Not yet reported Hoffmann-La Roche 310 participants Est. completion 2023-02-28 77 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT02174172
A Study to Assess the Safety and Tolerability of Atezolizumab in Combination With Other Immune-Modulating Therapies in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Hoffmann-La Roche 158 participants Est. completion 2019-11-25 9 sites Stand-aloneOther conditions: Solid CancersView official trial listing → -
Completed NCT NCT02220842
A Safety and Pharmacology Study of Atezolizumab (MPDL3280A) Administered With Obinutuzumab or Tazemetostat in Participants With Relapsed/Refractory Follicular Lymphoma and Diffuse Large B-cell Lymphoma
Not yet reported Hoffmann-La Roche 96 participants Est. completion 2020-01-21 15 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT02291289
A Study of Biomarker-Driven Therapy in Metastatic Colorectal Cancer (mCRC)
Not yet reported Hoffmann-La Roche 1044 participants Est. completion 2021-03-24 154 sites Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Terminated NCT NCT02298153
A Study of Atezolizumab in Combination With Epacadostat in Subjects With Previously Treated Stage IIIB or Stage IV Non-Small Cell Lung Cancer and Previously Treated Stage IV Urothelial Carcinoma
Not yet reported Incyte Corporation 29 participants Est. completion 2017-11-08 6 sites Stand-aloneOther conditions: NSCLC (Non-small Cell Lung Carcinoma), UC (Urothelial Cancer)View official trial listing → -
Completed NCT NCT02302807
A Study of Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211]
Not yet reported Hoffmann-La Roche 931 participants Est. completion 2018-11-08 217 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Terminated NCT NCT02303951
Neoadjuvant Vemurafenib + Cobimetinib + Atezolizumab in Melanoma: NEO-VC
Not yet reported University Hospital Tuebingen 47 participants Est. completion 2020-05-14 7 sites Stand-aloneOther conditions: Malignant MelanomaView official trial listing → -
Completed NCT NCT02304393
A Study of Selicrelumab (RO7009789) in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Solid Tumors
Not yet reported Hoffmann-La Roche 140 participants Est. completion 2019-11-07 11 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT02311361
Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 65 participants Est. completion 2020-12-31 1 siteOther conditions: Pancreatic Neoplasms, Pancreatic Cancer, Cancer of Pancreas, Cancer of the Pancreas, Pancreas CancerView official trial listing → -
Completed NCT NCT02314481
Deciphering Antitumour Response and Resistance With INtratumour Heterogeneity
Not yet reported University College, London 50 participants Est. completion 2025-11-30 1 siteOther conditions: Non-small Cell Lung CancerView official trial listing → -
Terminated NCT NCT02322814
A Study of Cobimetinib Plus Paclitaxel, Cobimetinib Plus Atezolizumab Plus Paclitaxel, or Cobimetinib Plus Atezolizumab Plus Nab-Paclitaxel as Initial Treatment for Participants With Triple-Negative Breast Cancer That Has Spread
Not yet reported Hoffmann-La Roche 169 participants Est. completion 2021-09-17 53 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02323191
A Study of Emactuzumab and Atezolizumab Administered in Combination in Participants With Advanced Solid Tumors
Not yet reported Hoffmann-La Roche 221 participants Est. completion 2020-08-21 12 sites Stand-aloneOther conditions: Solid CancersView official trial listing → -
Completed NCT NCT02350673
A Study of Intravenous (IV) Cergutuzumab Amunaleukin and Atezolizumab in Combination in Participants With Locally Advanced and/or Metastatic Solid Tumors
Not yet reported Hoffmann-La Roche 70 participants Est. completion 2019-12-16 14 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT02366143
A Study of Atezolizumab in Combination With Carboplatin Plus (+) Paclitaxel With or Without Bevacizumab Compared With Carboplatin+Paclitaxel+Bevacizumab in Participants With Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Not yet reported Hoffmann-La Roche 1202 participants Est. completion 2020-12-07 240 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT02367781
A Study of Atezolizumab in Combination With Carboplatin Plus (+) Nab-Paclitaxel Compared With Carboplatin+Nab-Paclitaxel in Participants With Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Not yet reported Hoffmann-La Roche 723 participants Est. completion 2021-01-18 132 sites Stand-aloneOther conditions: Carcinoma, Non-Squamous Non-Small Cell LungView official trial listing → -
Completed NCT NCT02367794
A Study of Atezolizumab in Combination With Carboplatin + Paclitaxel or Carboplatin + Nab-Paclitaxel Compared With Carboplatin + Nab-Paclitaxel in Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower131]
Not yet reported Hoffmann-La Roche 1021 participants Est. completion 2021-02-17 242 sites Stand-aloneOther conditions: Squamous Non-Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT02400814
MPDL3280A and Stereotactic Ablative Radiotherapy in Patients With Non-small Cell Lung Cancer
Not yet reported Megan Daly, MD 27 participants Est. completion 2021-09-29 1 siteOther conditions: Recurrent Non-Small Cell Lung Carcinoma, Stage IV Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02403271
A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Solid Tumors
Not yet reported, Not yet reported Pharmacyclics LLC. 124 participants Est. completion 2017-08 17 sitesOther conditions: Non-Small Cell Lung Cancer, Breast Cancer, Pancreatic CancerView official trial listing → -
Completed NCT NCT02409342
A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110]
Not yet reported Hoffmann-La Roche 572 participants Est. completion 2022-03-08 142 sites Stand-aloneOther conditions: Non-Squamous Non-Small Cell Lung Cancer, Squamous Non-Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT02409355
A Study of Atezolizumab Compared With Gemcitabine Plus (+) Cisplatin or Carboplatin for PD-L1-Selected Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower111)
Not yet reported Hoffmann-La Roche 8 participants Est. completion 2017-12-07 82 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02410512
A Study to Assess the Safety and Pharmacokinetics of MOXR0916 and Atezolizumab (Also Known as MPDL3280A or Anti-PD-L1) in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Genentech, Inc. 610 participants Est. completion 2019-11-22 27 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Completed NCT NCT02420821
A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma (RCC)
Not yet reported Hoffmann-La Roche 915 participants Est. completion 2021-12-13 154 sites Stand-aloneOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT02423863
In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol®
Not yet reported Oncovir, Inc. 26 participants Est. completion 2020-08-31 5 sites Stand-aloneOther conditions: Melanoma, Head and Neck Cancer, Sarcoma, Non-Melanoma Skin CancersView official trial listing → -
Completed NCT NCT02425891
A Study of Atezolizumab in Combination With Nab-Paclitaxel Compared With Placebo With Nab-Paclitaxel for Participants With Previously Untreated Metastatic Triple-Negative Breast Cancer (IMpassion130)
Not yet reported Hoffmann-La Roche 902 participants Est. completion 2021-08-31 247 sites Stand-aloneOther conditions: Triple Negative Breast CancerView official trial listing → -
Completed NCT NCT02431208
A Study of Atezolizumab (Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) Alone or in Combination With an Immunomodulatory Drug and/or Daratumumab in Participants With Multiple Myeloma (MM)
Not yet reported Hoffmann-La Roche 85 participants Est. completion 2021-03-19 31 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Terminated NCT NCT02450331
A Study of Atezolizumab Versus Observation as Adjuvant Therapy in Participants With High-Risk Muscle-Invasive Urothelial Carcinoma (UC) After Surgical Resection
Not yet reported Hoffmann-La Roche 809 participants Est. completion 2022-06-14 186 sites Stand-aloneOther conditions: Carcinoma, Transitional CellView official trial listing → -
Completed NCT NCT02451423
Neoadjuvant Atezolizumab in Localized Bladder Cancer
Not yet reported Lawrence Fong 23 participants Est. completion 2023-03-31 1 site Stand-aloneOther conditions: Carcinoma, Transitional CellView official trial listing → -
Status unknown NCT NCT02453984
MPDL3280A-imaging-IST-UMCG
Not yet reported University Medical Center Groningen 45 participants Est. completion 2024-06 1 siteOther conditions: Locally Advanced or Metastatic Solid Tumors Irrespective of PD-L1 ExpressionView official trial listing → -
Completed NCT NCT02458638
A Study of Atezolizumab in Advanced Solid Tumors
Not yet reported Hoffmann-La Roche 474 participants Est. completion 2020-07-28 48 sites Stand-aloneOther conditions: TumorsView official trial listing → -
Completed NCT NCT02463994
A Pilot Study of MPDL3280A and HIGRT in Metastatic NSCLC
Not yet reported University of Michigan Rogel Cancer Center 12 participants Est. completion 2018-11-07 2 sitesOther conditions: Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT02471846
A Study of GDC-0919 and Atezolizumab Combination Treatment in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Genentech, Inc. 158 participants Est. completion 2019-10-02 18 sites Stand-aloneOther conditions: Solid TumorView official trial listing → -
Status unknown NCT NCT02478099
MPDL3280A-treatment-IST-UMCG
Not yet reported University Medical Center Groningen 81 participants Est. completion 2024-07 1 siteOther conditions: Locally Advanced or Metastatic Solid TumorsView official trial listing → -
Completed NCT NCT02486718
Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lung Cancer [IMpower010]
Not yet reported Hoffmann-La Roche 1280 participants Est. completion 2026-08-26 216 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Withdrawn NCT NCT02495636
Phase 2 Study of MPDL3280A Combined With CDX-1401 in NY-ESO 1 (+) IIIB, IV or Recurrent Non-Small Cell Lung Cancer
Not yet reported Yale University Est. completion 2017-07 1 siteOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02500407
A Safety, Efficacy and Pharmacokinetic Study of BTCT4465A (Mosunetuzumab) as a Single Agent and Combined With Atezolizumab in Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)
Not yet reported, Not yet reported Genentech, Inc. 713 participants Est. completion 2025-09-01 35 sites Stand-aloneOther conditions: Lymphocytic Leukemia, Chronic, Lymphoma, Non HodgkinView official trial listing → -
Completed NCT NCT02508870
A Study of Atezolizumab Administered Alone or in Combination With Azacitidine in Participants With Myelodysplastic Syndromes
Not yet reported Hoffmann-La Roche 46 participants Est. completion 2019-06-10 15 sites Stand-aloneOther conditions: Myelodysplastic SyndromesView official trial listing → -
Active, not recruiting NCT NCT02525757
MPDL3280A With Chemoradiation for Lung Cancer
Not yet reported M.D. Anderson Cancer Center 52 participants Est. completion 2028-01-31 1 siteOther conditions: Lung Cancer, Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02530489
Nab-Paclitaxel and Atezolizumab Before Surgery in Treating Patients With Triple Negative Breast Cancer
Not yet reported M.D. Anderson Cancer Center 37 participants Est. completion 2025-05-23 1 site Stand-aloneOther conditions: Breast Adenocarcinoma, Invasive Breast Carcinoma, Triple-Negative Breast CarcinomaView official trial listing → -
Terminated NCT NCT02541604
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Preliminary Efficacy of Atezolizumab (Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) in Pediatric and Young Adult Participants With Solid Tumors
Not yet reported, Not yet reported Hoffmann-La Roche 87 participants Est. completion 2019-06-06 30 sites Stand-aloneOther conditions: Solid TumorView official trial listing → -
Terminated NCT NCT02543645
A Study of Varlilumab and Atezolizumab in Patients With Advanced Cancer
Not yet reported Celldex Therapeutics 18 participants Est. completion 2017-05-22 4 sites Stand-aloneOther conditions: Carcinoma, Renal Cell, Kidney Diseases, Kidney Neoplasms, Urogenital Neoplasms, Urologic Diseases, Urologic Neoplasms, Neoplasms by Histologic Type, Neoplasms, Clear-cell Metastatic Renal Cell Carcinoma, Melanoma, Triple Negative Breast Cancer, Bladder Cancer, Head and Neck Cancer, Non-small Cell Lung CancerView official trial listing → -
Approved For Marketing NCT NCT02589717
An Expanded Access Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Carcinoma After Failure With Platinum-Containing Chemotherapy
Genentech, Inc. Est. completion 2016-08 40 sitesOther conditions: Urothelial CarcinomaView official trial listing → -
Completed NCT NCT02594384
A Phase I Dose Escalation Study of the Safety and Pharmacokinetics of LAM-002A In Patients With Non-Hodgkin's Lymphoma
Not yet reported IRulya Therapeutics Inc. 62 participants Est. completion 2023-03-30 11 sites Stand-aloneOther conditions: Lymphoma, Non-Hodgkin; Leukemia, Chronic LymphocyticView official trial listing → -
Completed NCT NCT02596971
A Study of Atezolizumab in Combination With Either Obinutuzumab Plus Bendamustine or Obinutuzumab Plus (+) Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Participants With Follicular Lymphoma (FL) or Rituximab + CHOP in Participants With Diffuse Large B-Cell Lymphoma (DLBCL)
Not yet reported, Not yet reported Hoffmann-La Roche 91 participants Est. completion 2020-05-08 21 sites Stand-aloneOther conditions: Diffuse Large B-Cell Lymphoma, Lymphoma FollicularView official trial listing → -
Completed NCT NCT02599454
Atezolizumab and Stereotactic Body Radiation Therapy in Treating Patients With Non-small Cell Lung Cancer
Not yet reported Megan Daly, MD 20 participants Est. completion 2024-02-20 2 sites Stand-aloneOther conditions: Stage I Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02605915
Safety and Pharmacokinetics of Atezolizumab Combination Treatments in Participants With HER2-Positive and HER2-Negative Breast Cancer
Not yet reported Hoffmann-La Roche 98 participants Est. completion 2019-11-13 20 sites Stand-aloneOther conditions: HER2-Positive Metastatic Breast Cancer, HER2-Negative Metastatic Breast Cancer, Locally Advanced or Early Breast CancerView official trial listing → -
Terminated NCT NCT02609984
Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002)
Not yet reported Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 89 participants Est. completion 2019-02-06 18 sites Stand-aloneObstructive sleep apnea Other conditions: Sarcoma, Synovial Sarcoma, Metastatic Sarcoma, Recurrent Adult Soft Tissue Sarcoma, Locally Advanced SarcomaView official trial listing → -
Completed NCT NCT02620280
Neoadjuvant Therapy in TRIPle Negative Breast Cancer With antiPDL1
Not yet reported Fondazione Michelangelo 278 participants Est. completion 2024-01-07 41 sitesOther conditions: Invasive Ductal Breast CarcinomaView official trial listing → -
Terminated NCT NCT02630186
A Phase 1b/2 Study of Safety and Efficacy of Rociletinib in Combination With MPDL3280A in Patients With Advanced or Metastatic EGFR-mutant NSCLC
Not yet reported, Not yet reported Clovis Oncology, Inc. 3 participants Est. completion 2017-09-05 1 siteOther conditions: Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT02631577
A Study Evaluating the Safety and Efficacy of Atezolizumab in Combination With Obinutuzumab Plus Lenalidomide in Patients With Relapsed or Refractory Follicular Lymphoma
Not yet reported, Not yet reported Hoffmann-La Roche 38 participants Est. completion 2020-10-07 16 sites Stand-aloneOther conditions: Lymphoma, FollicularView official trial listing → -
Completed NCT NCT02650713
A Study of the Safety, Pharmacokinetics, and Therapeutic Activity of RO6958688 in Combination With Atezolizumab in Participants With Locally Advanced and/or Metastatic Carcinoembryonic Antigen (CEA)-Positive Solid Tumors
Not yet reported Hoffmann-La Roche 228 participants Est. completion 2020-01-13 24 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Completed NCT NCT02655822
Phase 1/1b Study to Evaluate the Safety and Tolerability of Ciforadenant Alone and in Combination With Atezolizumab in Advanced Cancers
Not yet reported Corvus Pharmaceuticals, Inc. 502 participants Est. completion 2021-07 20 sites Stand-aloneOther conditions: Renal Cell Cancer, Metastatic Castration Resistant Prostate CancerView official trial listing → -
Completed NCT NCT02657434
A Study of Atezolizumab in Combination With Carboplatin or Cisplatin + Pemetrexed Compared With Carboplatin or Cisplatin + Pemetrexed in Participants Who Are Chemotherapy-Naive and Have Stage IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (IMpower 132)
Not yet reported Hoffmann-La Roche 578 participants Est. completion 2022-12-13 183 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02659384
Anti-programmed Cell Death-1 Ligand 1 (aPDL-1) Antibody Atezolizumab, Bevacizumab and Acetylsalicylic Acid in Recurrent Platinum Resistant Ovarian Cancer
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 122 participants Est. completion 2022-03 12 sites Stand-aloneOther conditions: Ovarian NeoplasmsView official trial listing → -
Completed NCT NCT02662309
Preoperative MPDL3280A in Transitional Cell Carcinoma of the Bladder
Not yet reported Queen Mary University of London 96 participants Est. completion 2020-06-11 20 sitesOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT02664935
National Lung Matrix Trial: Multi-drug Phase II Trial in Non-Small Cell Lung Cancer
Not yet reported University of Birmingham 423 participants Est. completion 2023-11-29 25 sitesOther conditions: Non-Small Cell Lung Cancer, Carcinoma, Squamous Cell, AdenocarcinomaView official trial listing → -
Completed NCT NCT02705196
LOAd703 Oncolytic Virus Therapy for Pancreatic Cancer
Not yet reported, Not yet reported Lokon Pharma AB 51 participants Est. completion 2025-11-15 2 sites Stand-aloneOther conditions: Pancreatic CancerView official trial listing → -
Completed NCT NCT02708680
Randomized Phase 2 Study of Atezolizumab and Entinostat in Patients With aTN Breast Cancer With Phase 1b Lead In
Not yet reported, Not yet reported Syndax Pharmaceuticals 89 participants Est. completion 2021-03-31 29 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT02715531
A Study of the Safety and Efficacy of Atezolizumab Administered in Combination With Bevacizumab and/or Other Treatments in Participants With Solid Tumors
Not yet reported Hoffmann-La Roche 243 participants Est. completion 2021-05-31 30 sites Stand-aloneOther conditions: Solid TumorView official trial listing → -
Completed NCT NCT02716038
Neoadjuvant MPDL3280A, Nab-paclitaxel and Carboplatin (MAC) in NSCLC
Not yet reported Columbia University 39 participants Est. completion 2022-10-01 3 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT02724878
Study of Atezolizumab + Bevacizumab in Patients With Advanced Non-Clear Cell Renal Cell Carcinoma
Not yet reported Dana-Farber Cancer Institute 65 participants Est. completion 2024-12-31 4 sites Stand-aloneOther conditions: Advanced Non-Clear Cell Kidney CancerView official trial listing → -
Completed NCT NCT02729896
A Study Evaluating Safety and Efficacy of Obinutuzumab, Polatuzumab Vedotin (Pola), and Atezolizumab (Atezo) in Participants With Relapsed or Refractory Follicular Lymphoma (FL) and Rituximab, Atezo, and Pola in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Not yet reported, Not yet reported Hoffmann-La Roche 36 participants Est. completion 2019-10-07 19 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT02733042
A Study to Determine Dose, Safety, and Efficacy of Durvalumab as Monotherapy and in Combination Therapy in Subjects With Lymphoma or Chronic Lymphocytic Leukemia
Not yet reported, Not yet reported Celgene 106 participants Est. completion 2022-08-21 66 sitesOther conditions: Lymphoma, Leukemia, Lymphocytic, Chronic, B-CellView official trial listing → -
Terminated NCT NCT02748889
Carboplatin Plus Etoposide With or Without MPDL3280A in Untreated Extensive Stage Small Cell Lung Cancer
Not yet reported, Not yet reported Giuseppe Giaccone 1 participants Est. completion 2017-05-09 1 site Stand-aloneOther conditions: Small Cell Lung Cancer ( SCLC )View official trial listing → -
Completed NCT NCT02763579
A Study of Carboplatin Plus Etoposide With or Without Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)
Not yet reported Hoffmann-La Roche 503 participants Est. completion 2022-07-07 114 sites Stand-aloneOther conditions: Small Cell Lung CarcinomaView official trial listing → -
Completed NCT NCT02777710
Evaluation of Safety and Activity of an Anti-PDL1 Antibody (DURVALUMAB) Combined With CSF-1R TKI (PEXIDARTINIB) in Patients With Metastatic/Advanced Pancreatic or Colorectal Cancers
Not yet reported Centre Leon Berard 48 participants Est. completion 2019-12 2 sitesOther conditions: Colorectal Cancer, Pancreatic Cancer, Metastatic Cancer, Advanced CancerView official trial listing → -
Terminated NCT NCT02784483
Pilot Study Of Anti-Programmed Death Ligand-1 (Anti-PD-L1, Atezolizumab) In Asymptomatic Myeloma
Not yet reported Yale University 2 participants Est. completion 2019-04-22 1 site Stand-aloneOther conditions: Asymptomatic MyelomaView official trial listing → -
Completed NCT NCT02788279
A Study to Investigate Efficacy and Safety of Cobimetinib Plus Atezolizumab and Atezolizumab Monotherapy Versus Regorafenib in Participants With Metastatic Colorectal Adenocarcinoma (COTEZO IMblaze370)
Not yet reported Hoffmann-La Roche 363 participants Est. completion 2018-12-26 73 sites Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Terminated NCT NCT02792192
Safety and Pharmacology Study of Atezolizumab Alone and in Combination With Bacille Calmette-Guérin (BCG) in High-Risk Non-Muscle-Invasive Bladder Cancer (NMIBC) Participants
Not yet reported, Not yet reported Hoffmann-La Roche 24 participants Est. completion 2020-09-29 8 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT02794571
Safety and Pharmacokinetics (PK) of Escalating Doses of Tiragolumab as a Single Agent and in Combination With Atezolizumab and/or Other Anti-Cancer Therapies in Locally Advanced or Metastatic Tumors
Not yet reported Genentech, Inc. 518 participants Est. completion 2024-11-13 28 sites Stand-aloneOther conditions: Advanced/Metastatic TumorsView official trial listing → -
Completed NCT NCT02807636
Study of Atezolizumab as Monotherapy and in Combination With Platinum-Based Chemotherapy in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma
Not yet reported Hoffmann-La Roche 1213 participants Est. completion 2024-02-12 204 sites Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Completed NCT NCT02811497
Study of Azacitidine and Durvalumab in Advanced Solid Tumors
Not yet reported University Health Network, Toronto 28 participants Est. completion 2020-08-04 1 siteObstructive sleep apnea Other conditions: Platinum Resistant Epithelial Ovarian Cancer Type II, Estrogen Receptor Positive and HER2 Negative Breast CancerView official trial listing → -
Completed NCT NCT02813785
A Study of Atezolizumab Compared With Docetaxel in Non-Small Cell Lung Cancer (NSCLC) After Failure With Platinum-Containing Chemotherapy
Not yet reported Hoffmann-La Roche 565 participants Est. completion 2022-12-27 38 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT02814669
Safety and Tolerability of Atezolizumab (ATZ) in Combination With Radium-223 Dichloride (R-223-D) in Metastatic Castrate-Resistant Prostate Cancer (CRPC) Progressed Following Treatment With an Androgen Pathway Inhibitor
Not yet reported Hoffmann-La Roche 45 participants Est. completion 2019-07-31 17 sites Stand-aloneOther conditions: Castrate-Resistant Prostate CancerView official trial listing → -
Completed NCT NCT02825940
A Study to Assess the Pharmacokinetics, Efficacy, and Safety of Atezolizumab Administered Intravenously (IV) as a Single Agent or in Combination With Chemotherapy in Chinese Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Hoffmann-La Roche 120 participants Est. completion 2022-11-04 7 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT02839707
Pegylated Liposomal Doxorubicin Hydrochloride With Atezolizumab and/or Bevacizumab in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 444 participants Est. completion 2027-05-11 919 sites Stand-aloneOther conditions: Fallopian Tube High Grade Serous Adenocarcinoma, Ovarian High Grade Serous Adenocarcinoma, Ovarian Seromucinous Carcinoma, Primary Peritoneal High Grade Serous Adenocarcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Fallopian Tube Clear Cell Adenocarcinoma, Recurrent Fallopian Tube Endometrioid Adenocarcinoma, Recurrent Fallopian Tube Undifferentiated Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Ovarian Clear Cell Adenocarcinoma, Recurrent Ovarian Endometrioid Adenocarcinoma, Recurrent Ovarian Undifferentiated Carcinoma, Recurrent Platinum-Resistant Fallopian Tube Carcinoma, Recurrent Platinum-Resistant Ovarian Carcinoma, Recurrent Platinum-Resistant Primary Peritoneal Carcinoma, Recurrent Primary Peritoneal Carcinoma, Recurrent Primary Peritoneal Clear Cell Adenocarcinoma, Recurrent Primary Peritoneal Endometrioid Adenocarcinoma, Recurrent Primary Peritoneal Undifferentiated CarcinomaView official trial listing → -
Completed NCT NCT02844816
Atezolizumab in Treating Patients With Recurrent BCG-Unresponsive Non-muscle Invasive Bladder Cancer
Not yet reported National Cancer Institute (NCI) 172 participants Est. completion 2024-06-26 272 sites Stand-aloneOther conditions: Recurrent Bladder Urothelial Carcinoma, Stage 0a Bladder Urothelial Carcinoma AJCC v6 and v7, Stage 0is Bladder Urothelial Carcinoma AJCC v6 and v7, Stage I Bladder Urothelial Carcinoma AJCC v6 and v7View official trial listing → -
Active, not recruiting NCT NCT02846623
Atezolizumab, Obinutuzumab, and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Relapsed or Refractory Richter Syndrome
Not yet reported M.D. Anderson Cancer Center 50 participants Est. completion 2027-02-28 1 site Stand-aloneOther conditions: Chronic Lymphocytic Leukemia, Recurrent Transformed Chronic Lymphocytic Leukemia, Refractory Transformed Chronic Lymphocytic Leukemia, Richter Syndrome, Small Lymphocytic LymphomaView official trial listing → -
Completed NCT NCT02848651
A Study of Atezolizumab as First-line Monotherapy for Advanced or Metastatic Non-Small Cell Lung Cancer
Not yet reported Genentech, Inc. 153 participants Est. completion 2019-05-14 20 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT02849496
Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer
Not yet reported National Cancer Institute (NCI) 89 participants Est. completion 2027-08-26 58 sites Stand-aloneOther conditions: Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Locally Advanced Unresectable Breast Carcinoma, Metastatic Breast CarcinomaView official trial listing → -
Active, not recruiting NCT NCT02862275
Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer
Not yet reported National Cancer Institute (NCI) 40 participants Est. completion 2026-11-21 9 sites Stand-aloneOther conditions: Hematopoietic and Lymphoid Cell Neoplasm, Metastatic Malignant Solid Neoplasm, Unresectable Malignant Solid NeoplasmView official trial listing → -
Withdrawn NCT NCT02871323
Durvalumab in Treating Patients With Primary, Post-Polycythemia Vera, or Post-Essential Thrombocythemia Myelofibrosis
Not yet reported Northwestern University 1 siteOther conditions: Polycythemia Vera, Post-Polycythemic Myelofibrosis Phase, Primary MyelofibrosisView official trial listing → -
Completed NCT NCT02873195
Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal Cancer
Not yet reported Academic and Community Cancer Research United 133 participants Est. completion 2023-12-01 10 sites Stand-aloneOther conditions: Metastatic Colorectal Carcinoma, Recurrent Colorectal Carcinoma, Refractory Colorectal Carcinoma, Stage IV Colorectal Cancer AJCC v7, Stage IVA Colorectal Cancer AJCC v7, Stage IVB Colorectal Cancer AJCC v7View official trial listing → -
Completed NCT NCT02876224
Study of Cobimetinib in Combination With Atezolizumab and Bevacizumab in Participants With Gastrointestinal and Other Tumors
Not yet reported Hoffmann-La Roche 51 participants Est. completion 2019-06-25 6 sites Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Completed NCT NCT02876510
ACTolog in Patients With Solid Cancers
Not yet reported Immatics US, Inc. 38 participants Est. completion 2021-09-22 1 site Stand-aloneOther conditions: Cancer, Solid TumorView official trial listing → -
Active, not recruiting NCT NCT02883062
Carboplatin and Paclitaxel With or Without Atezolizumab Before Surgery in Treating Patients With Newly Diagnosed, Stage II-III Triple-Negative Breast Cancer
Not yet reported National Cancer Institute (NCI) 67 participants Est. completion 2027-09-30 14 sites Stand-aloneOther conditions: Invasive Breast Carcinoma, Stage II Breast Cancer AJCC v6 and v7, Stage III Breast Cancer AJCC v7, Triple-Negative Breast CarcinomaView official trial listing → -
Terminated NCT NCT02890368
Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoides
Not yet reported Pfizer 56 participants Est. completion 2020-03-31 7 sites Stand-aloneOther conditions: Solid Tumors, Mycosis Fungoides, Melanoma, Merkel-cell Carcinoma, Squamous Cell Carcinoma, Breast Carcinoma, Human Papillomavirus-Related Malignant Neoplasm, Soft Tissue SarcomaView official trial listing → -
Completed NCT NCT02891824
ATALANTE: Atezolizumab vs Placebo Phase III Study in Late Relapse Ovarian Cancer Treated With Chemotherapy+Bevacizumab
Not yet reported ARCAGY/ GINECO GROUP 614 participants Est. completion 2024-02-22 75 sites Stand-aloneOther conditions: Ovarian CancerView official trial listing → -
Completed NCT NCT02892318
A Study Evaluating the Safety and Pharmacology of Atezolizumab Administered in Combination With Immunomodulatory Agents in Participants With Acute Myeloid Leukemia (AML)
Not yet reported Hoffmann-La Roche 40 participants Est. completion 2019-12-12 8 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT02902029
Evaluating the Efficacy and Safety of a Sequencing Schedule of Cobimetinib Plus Vemurafenib Followed by Immunotherapy With an Anti- PD-L1 Antibody in Patients With Unresectable or Metastatic BRAF V600 Mutant Melanoma
Not yet reported University Hospital, Essen 186 participants Est. completion 2024-03 27 sites Stand-aloneOther conditions: Malignant MelanomaView official trial listing → -
Completed NCT NCT02908672
A Study of Atezolizumab Plus Cobimetinib and Vemurafenib Versus Placebo Plus Cobimetinib and Vemurafenib in Previously Untreated BRAFv600 Mutation-Positive Patients With Metastatic or Unresectable Locally Advanced Melanoma
Not yet reported Hoffmann-La Roche 514 participants Est. completion 2024-07-01 110 sites Stand-aloneOther conditions: MelanomaView official trial listing → -
Active, not recruiting NCT NCT02912559
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair
Not yet reported National Cancer Institute (NCI) 712 participants Est. completion 2026-12-18 1049 sites Stand-aloneOther conditions: Colon Adenocarcinoma, DNA Repair Disorder, Lynch Syndrome, Stage III Colon Cancer AJCC v8View official trial listing → -
Completed NCT NCT02914470
Carboplatin-cyclophosphamide Combined With Atezolizumab
Not yet reported The Netherlands Cancer Institute 12 participants Est. completion 2021-10 1 site Stand-aloneOther conditions: Breast Cancer, Cervix Cancer, Ovarian Cancer, Endometrial CancerView official trial listing → -
Terminated NCT NCT02919449
Dose Escalation Trial of Intra-Tumoral Injection of NIS Measles Virus in Combination With Atezolizumab
Not yet reported Vyriad, Inc. 2 participants Est. completion 2018-01-19 1 site Stand-aloneOther conditions: Recurrent Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02921269
Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical Cancer
Not yet reported National Cancer Institute (NCI) 11 participants Est. completion 2021-01-13 22 sites Stand-aloneOther conditions: Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified, Recurrent Cervical Carcinoma, Stage IV Cervical Cancer AJCC v6 and v7, Stage IVA Cervical Cancer AJCC v6 and v7, Stage IVB Cervical Cancer AJCC v6 and v7View official trial listing → -
Completed NCT NCT02924883
A Study to Evaluate the Efficacy and Safety of Trastuzumab Emtansine in Combination With Atezolizumab or Atezolizumab-Placebo in Participants With Human Epidermal Growth Factor-2 (HER2) Positive Locally Advanced or Metastatic Breast Cancer (BC) Who Received Prior Trastuzumab and Taxane Based Therapy
Not yet reported Hoffmann-La Roche 202 participants Est. completion 2020-02-06 68 sites Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT02926833
Study of Safety and Efficacy of KTE-C19 in Combination With Atezolizumab in Adults With Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
Not yet reported, Not yet reported Kite, A Gilead Company 37 participants Est. completion 2023-01-12 5 sites Stand-aloneOther conditions: Refractory Diffuse Large B Cell LymphomaView official trial listing → -
Completed NCT NCT02927301
A Study of Atezolizumab as Neoadjuvant and Adjuvant Therapy in Resectable Non-Small Cell Lung Cancer (NSCLC) - Lung Cancer Mutation Consortium (LCMC3)
Not yet reported Genentech, Inc. 181 participants Est. completion 2023-09-05 19 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT02928406
A Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract
Not yet reported Hoffmann-La Roche 1004 participants Est. completion 2022-12-12 175 sites Stand-aloneOther conditions: Urinary Tract CancerView official trial listing → -
Active, not recruiting NCT NCT02935361
Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed
Not yet reported, Not yet reported University of Southern California 33 participants Est. completion 2027-12-31 5 sites Stand-aloneOther conditions: Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related ChangesView official trial listing → -
Completed NCT NCT02951767
A Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer (Cohort 1)
Not yet reported Hoffmann-La Roche 119 participants Est. completion 2023-02-28 77 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Terminated NCT NCT02982694
Study With Atezolizumab Plus Bevacizumab in Patients With Chemotherapy Resistant, MSI-like, Colorectal Cancer
Not yet reported Vall d'Hebron Institute of Oncology 46 participants Est. completion 2020-11-27 7 sites Stand-aloneOther conditions: MSI, ColoRectal Cancer, Chemotherapy, Resistance, APCView official trial listing → -
Active, not recruiting NCT NCT02989584
A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer
Not yet reported, Not yet reported Memorial Sloan Kettering Cancer Center 54 participants Est. completion 2026-12 11 sites Stand-aloneOther conditions: Bladder Cancer, Metastatic Bladder Cancer, Urothelial CarcinomaView official trial listing → -
Completed NCT NCT02992912
Atezolizumab With Stereotactic Ablative Radiotherapy in Patients With Metastatic Tumours
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 138 participants Est. completion 2026-06-29 1 site Stand-aloneOther conditions: Patients With Metastatic Tumours (Colorectal Cancer, Non-small Lung Cancer, Renal Cell Carcinoma or Sarcoma )View official trial listing → -
Completed NCT NCT02994576
Atezolizumab as Induction Therapy in Non-small Cell Lung Cancer
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 60 participants Est. completion 2023-03 3 sites Stand-aloneOther conditions: Nonsmall Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT02997228
Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study
Not yet reported National Cancer Institute (NCI) 120 participants Est. completion 2027-06-01 445 sites Stand-aloneOther conditions: Metastatic Colorectal Adenocarcinoma, Stage IV Colorectal Cancer AJCC v7View official trial listing → -
Terminated NCT NCT03007719
Functional Imaging of T-Cell Activation With [18F]F-AraG in Urothelial Carcinoma Patients Receiving Neoadjuvant Therapy or Patients With Cancer Receiving Standard of Care Anti-PD-1/L1
Not yet reported Lawrence Fong 4 participants Est. completion 2019-01-11 1 site Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT03014648
Evaluating the Efficacy of Atezolizumab in Advanced Non-small Cell Lung Cancer (NSCLC)
Not yet reported Liza Villaruz, MD 28 participants Est. completion 2022-03-31 2 sites Stand-aloneOther conditions: Advanced Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT03016312
A Study of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Enzalutamide in Participants With Metastatic Castration-Resistant Prostrate Cancer (mCRPC) After Failure of an Androgen Synthesis Inhibitor And Failure of, Ineligibility For, or Refusal of a Taxane Regimen
Not yet reported Hoffmann-La Roche 759 participants Est. completion 2022-12-20 158 sites Stand-aloneOther conditions: Prostatic Neoplasms, Castration-ResistantView official trial listing → -
Completed NCT NCT03023423
A Study of Daratumumab in Combination With Atezolizumab Compared With Atezolizumab Alone in Participants With Previously Treated Advanced or Metastatic Non-Small Cell Lung Cancer
Not yet reported, Not yet reported Janssen Research & Development, LLC 100 participants Est. completion 2019-09-26 47 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT03024216
Clinical Study of Atezolizumab (Anti-PD-L1) and Sipuleucel-T in Patients With Asymptomatic or Minimally Symptomatic Metastatic Castrate Resistant Prostate Cancer
Not yet reported University of Hawaii 37 participants Est. completion 2020-12-31 3 sites Stand-aloneOther conditions: Prostate Cancer MetastaticView official trial listing → -
Terminated NCT NCT03024437
Atezolizumab in Combination With Entinostat and Bevacizumab in Patients With Advanced Renal Cell Carcinoma
Not yet reported, Not yet reported Roberto Pili 31 participants Est. completion 2024-06-24 4 sites Stand-aloneOther conditions: Metastatic Cancer, Renal CancerView official trial listing → -
Terminated NCT NCT03024996
A Study of Atezolizumab as Adjuvant Therapy in Participants With Renal Cell Carcinoma (RCC) at High Risk of Developing Metastasis Following Nephrectomy
Not yet reported Hoffmann-La Roche 778 participants Est. completion 2022-12-08 186 sites Stand-aloneOther conditions: Renal Cell CarcinomaView official trial listing → -
Terminated NCT NCT03029832
A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for Cisplatin-Based Therapy
Not yet reported Genentech, Inc. 5 participants Est. completion 2018-04-25 22 sites Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Completed NCT NCT03035890
Hypofractionated Radiation Therapy to Improve Immunotherapy Response in Non-Small Cell Lung Cancer
Not yet reported West Virginia University 35 participants Est. completion 2022-06-30 1 site Stand-aloneOther conditions: Non Small Cell Lung Cancer MetastaticView official trial listing → -
Completed NCT NCT03038100
A Study of Atezolizumab Versus Placebo in Combination With Paclitaxel, Carboplatin, and Bevacizumab in Participants With Newly-Diagnosed Stage III or Stage IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Not yet reported Hoffmann-La Roche 1301 participants Est. completion 2022-08-12 268 sites Stand-aloneOther conditions: Ovarian Cancer, Fallopian Tube Cancer, Peritoneal NeoplasmsView official trial listing → -
Completed NCT NCT03041311
Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib (G1T28), a CDK4/6 Inhibitor, in Extensive-Stage SCLC
Not yet reported G1 Therapeutics, Inc. 107 participants Est. completion 2020-10-29 45 sites Stand-aloneOther conditions: Small Cell Lung CancerView official trial listing → -
Completed NCT NCT03046953
Avelumab in Relapsed and Refractory Peripheral T-cell Lymphoma
Not yet reported University of Birmingham 35 participants Est. completion 2021-07-27 1 siteOther conditions: T-Cell Lymphoma Relapsed, T-Cell Lymphoma RefractoryView official trial listing → -
Terminated NCT NCT03050060
Image Guided Hypofractionated Radiation Therapy, Nelfinavir Mesylate, Pembrolizumab, Nivolumab and Atezolizumab in Treating Patients With Advanced Melanoma, Lung, or Kidney Cancer
Not yet reported University of Washington 21 participants Est. completion 2020-07-12 1 site Stand-aloneOther conditions: Metastatic Kidney Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Stage IV Cutaneous Melanoma AJCC v6 and v7, Stage IV Renal Cell Cancer AJCC v7, Stage IV Lung Non-Small Cell Cancer AJCC v7View official trial listing → -
Terminated NCT NCT03050814
Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004
Not yet reported National Cancer Institute (NCI) 30 participants Est. completion 2021-08-25 2 sitesOther conditions: Colorectal Tumors, Colorectal Neoplasms, Colorectal Carcinoma, Colorectal Adenocarcinoma, Colorectal CancerView official trial listing → -
Completed NCT NCT03056599
Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma
Not yet reported Presage Biosciences 23 participants Est. completion 2021-09-22 3 sitesOther conditions: Soft Tissue Sarcoma AdultView official trial listing → -
Completed NCT NCT03059667
Immunotherapy as Second-line in Patient With Small Cell Lung Cancer
Not yet reported Intergroupe Francophone de Cancerologie Thoracique 73 participants Est. completion 2020-12-01 18 sites Stand-aloneOther conditions: Small Cell Lung Cancer, Small Cell Lung Cancer Limited Stage, Small Cell Lung Cancer Extensive StageView official trial listing → -
Completed NCT NCT03063762
Study to Evaluate Safety, Pharmacokinetics and Therapeutic Activity of RO6874281 as a Combination Therapy in Participants With Unresectable Advanced and/or Metastatic Renal Cell Carcinoma (RCC)
Not yet reported Hoffmann-La Roche 69 participants Est. completion 2021-06-14 23 sites Stand-aloneOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT03073525
A Trial of Atezolizumab and Vigil in Patients With Advanced Gynecological Cancers
Not yet reported Gradalis, Inc. 25 participants Est. completion 2022-05-18 6 sites Stand-aloneOther conditions: Advanced Gynecological Cancers, Ovarian Cancer, Cervical Cancer, Uterine CancerView official trial listing → -
Active, not recruiting NCT NCT03074513
Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors
Not yet reported M.D. Anderson Cancer Center 133 participants Est. completion 2027-09-30 1 site Stand-aloneOther conditions: Appendix Adenocarcinoma, Human Papillomavirus-Related Anal Squamous Cell Carcinoma, Human Papillomavirus-Related Cervical Squamous Cell Carcinoma, Human Papillomavirus-Related Squamous Cell Carcinoma of the Penis, Human Papillomavirus-Related Vulvar Squamous Cell Carcinoma, Neuroendocrine Carcinoma, Pancreatic Neuroendocrine Tumor, Recurrent Merkel Cell Carcinoma, Recurrent Nasopharynx Carcinoma, Recurrent Peritoneal Malignant Mesothelioma, Recurrent Pleural Malignant Mesothelioma, Stage III Merkel Cell Carcinoma AJCC v7, Stage III Nasopharyngeal Carcinoma AJCC v7, Stage III Pleural Malignant Mesothelioma AJCC v7, Stage IV Merkel Cell Carcinoma AJCC v7, Stage IV Nasopharyngeal Carcinoma AJCC v7, Stage IV Pleural Malignant Mesothelioma AJCC v7, Stage IVA Nasopharyngeal Carcinoma AJCC v7, Stage IVB Nasopharyngeal Carcinoma AJCC v7, Stage IVC Nasopharyngeal Carcinoma AJCC v7, Vaginal Squamous Cell Carcinoma, Not Otherwise SpecifiedView official trial listing → -
Completed NCT NCT03087864
PDL-1 Targeting in Resectable Oesophageal Cancer
Not yet reported Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 40 participants Est. completion 2019-07-01 1 site Stand-aloneOther conditions: Esophageal Cancer, Stage II, Esophageal Cancer Stage IIIView official trial listing → -
Completed NCT NCT03093922
A Study of Two Dosing Schedules of Atezolizumab in Combination With Gemcitabine and Cisplatin as First-Line Treatment for Metastatic Bladder Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 32 participants Est. completion 2026-09-22 9 sites Stand-aloneOther conditions: Urothelial Carcinoma, Locally Advanced, UnresectableView official trial listing → -
Completed NCT NCT03101280
A Combination Study of Rucaparib and Atezolizumab in Participants With Advanced Gynecologic Cancers and Triple-Negative Breast Cancer
Not yet reported Hoffmann-La Roche 29 participants Est. completion 2020-08-11 11 sites Stand-aloneOther conditions: Gynecologic NeoplasmsView official trial listing → -
Completed NCT NCT03102242
Atezolizumab Immunotherapy in Patients With Advanced NSCLC
Not yet reported Alliance Foundation Trials, LLC. 64 participants Est. completion 2022-10-01 13 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT03108131
Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors
Not yet reported M.D. Anderson Cancer Center 49 participants Est. completion 2024-04-02 1 site Stand-aloneOther conditions: Skin Squamous Cell Carcinoma, Appendix Adenocarcinoma, Rare Lesion, Locally Advanced Malignant Neoplasm, Locally Advanced Skin Squamous Cell Carcinoma, Metastatic Malignant Neoplasm, Metastatic Skin Squamous Cell Carcinoma, Metastatic Small Intestinal Adenocarcinoma, Rare Neoplastic Syndrome, Refractory Malignant Neoplasm, Stage IV Small Intestinal Adenocarcinoma AJCC v8, Unresectable Malignant NeoplasmView official trial listing → -
Terminated NCT NCT03115801
A Phase II Randomized Trial of Immunotherapy Plus Radiotherapy in Metastatic Genitourinary Cancers
Not yet reported Weill Medical College of Cornell University 6 participants Est. completion 2020-10-13 1 siteOther conditions: Metastatic Renal Cell Carcinoma, Metastatic Urothelial CarcinomaView official trial listing → -
Terminated NCT NCT03120676
Study of Atezolizumab in Relapsed or Refractory Hodgkin Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 3 participants Est. completion 2018-11-12 6 sites Stand-aloneOther conditions: Hodgkin LymphomaView official trial listing → -
Completed NCT NCT03125902
A Study of Atezolizumab and Paclitaxel Versus Placebo and Paclitaxel in Participants With Previously Untreated Locally Advanced or Metastatic Triple Negative Breast Cancer (TNBC)
Not yet reported Hoffmann-La Roche 653 participants Est. completion 2023-01-17 161 sites Stand-aloneOther conditions: Triple-Negative Breast CancerView official trial listing → -
Active, not recruiting NCT NCT03125928
Clinical Trial of Atezolizumab With Paclitaxel, Trastuzumab, and Pertuzumab in Patients With Metastatic HER-2 Positive Breast Cancer
Not yet reported Fox Chase Cancer Center 16 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: HER2-positive Breast CancerView official trial listing → -
Completed NCT NCT03127007
Safety and Efficacy of Atezolizumab Combined to Preoperative Radio-chemotherapy in Localized Rectal Cancer
Not yet reported, Not yet reported Grand Hôpital de Charleroi 45 participants Est. completion 2024-10-15 5 sites Stand-aloneOther conditions: Rectal NeoplasmsView official trial listing → -
Terminated NCT NCT03138889
Bempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid Tumors
Not yet reported, Not yet reported Nektar Therapeutics 162 participants Est. completion 2022-08-24 38 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT03141684
Testing Atezolizumab Alone or Atezolizumab Plus Bevacizumab in People With Advanced Alveolar Soft Part Sarcoma
Not yet reported National Cancer Institute (NCI) 63 participants Est. completion 2027-10-31 42 sites Stand-aloneOther conditions: Metastatic Alveolar Soft Part Sarcoma, Unresectable Alveolar Soft Part SarcomaView official trial listing → -
Terminated NCT NCT03147040
AssessinG Efficacy of Carboplatin and ATezOlizumab in Metastatic Lobular Breast Cancer
Not yet reported The Netherlands Cancer Institute 23 participants Est. completion 2022-07-01 4 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Active, not recruiting NCT NCT03148418
A Study in Participants Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study (IMbrella A)
Not yet reported Hoffmann-La Roche 382 participants Est. completion 2026-11-30 170 sites Stand-aloneOther conditions: CancerView official trial listing → -
Terminated NCT NCT03154827
Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab for Maintenance Treatment in Subjects With Acute Myeloid Leukemia (AML)
Not yet reported, Not yet reported BioLineRx, Ltd. 1 participants Est. completion 2020-04-01 12 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03158389
NCT Neuro Master Match - N²M² (NOA-20)
Not yet reported, Not yet reported University Hospital Heidelberg 228 participants Est. completion 2023-02-22 13 sites Stand-aloneOther conditions: Glioblastoma, AdultView official trial listing → -
Completed NCT NCT03164993
Atezolizumab Combined With Immunogenic Chemotherapy in Patients With Metastatic Triple-negative Breast Cancer
Not yet reported Oslo University Hospital 68 participants Est. completion 2023-09-30 5 sitesOther conditions: Cancer, Breast, Triple Negative Breast CancerView official trial listing → -
Active, not recruiting NCT NCT03170960
Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors
Not yet reported Exelixis 914 participants Est. completion 2027-09-30 124 sites Stand-aloneOther conditions: Urothelial Carcinoma, Renal Cell Carcinoma, Non-Small Cell Lung Cancer, Castration-resistant Prostate Cancer, Triple Negative Breast Cancer, Ovarian Cancer, Endometrial Cancer, Hepatocellular Carcinoma, Gastric Cancer, Gastroesophageal Junction Adenocarcinoma, Colorectal Cancer, Head and Neck Cancer, Differentiated Thyroid Cancer, Lower Esophageal CancerView official trial listing → -
Completed NCT NCT03174197
Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 60 participants Est. completion 2025-09-17 1 site Stand-aloneObstructive sleep apnea Other conditions: GlioblastomaView official trial listing → -
Active, not recruiting NCT NCT03175432
Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases
Not yet reported M.D. Anderson Cancer Center 29 participants Est. completion 2028-06-30 1 site Stand-aloneOther conditions: BRAF V600 Wild Type, Clinical Stage IV Cutaneous Melanoma AJCC v8, Intracranial Melanoma, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma, Pathologic Stage IV Cutaneous Melanoma AJCC v8, Refractory MelanomaView official trial listing → -
Active, not recruiting NCT NCT03178552
A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)
Not yet reported, Not yet reported Hoffmann-La Roche 1000 participants Est. completion 2027-06-30 161 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT03178851
Cobimetinib (Targeted Therapy) Plus Atezolizumab (Immunotherapy) in Participants With Advanced Melanoma Whose Cancer Has Worsened During or After Treatment With Previous Immunotherapy and Atezolizumab Monotherapy in Participants With Previously Untreated Advanced Melanoma
Not yet reported Hoffmann-La Roche 155 participants Est. completion 2020-09-21 43 sites Stand-aloneOther conditions: Malignant MelanomaView official trial listing → -
Active, not recruiting NCT NCT03179943
Atezolizumab + Guadecitabine in Patients With Checkpoint Inhibitor Refractory or Resistant Urothelial Carcinoma
Not yet reported Fox Chase Cancer Center 21 participants Est. completion 2022-07 3 sites Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03181100
Atezolizumab With Chemotherapy in Treating Patients With Anaplastic or Poorly Differentiated Thyroid Cancer
Not yet reported M.D. Anderson Cancer Center 50 participants Est. completion 2027-07-31 1 site Stand-aloneOther conditions: Metastatic Thyroid Gland Carcinoma, Poorly Differentiated Thyroid Gland Carcinoma, Stage IVA Thyroid Gland Anaplastic Carcinoma AJCC v8, Stage IVB Thyroid Gland Anaplastic Carcinoma AJCC v8, Stage IVC Thyroid Gland Anaplastic Carcinoma AJCC v8, Thyroid Gland Anaplastic Carcinoma, Unresectable Thyroid Gland CarcinomaView official trial listing → -
Completed NCT NCT03191786
A Study of Atezolizumab Compared With a Single-Agent Chemotherapy in Treatment Naïve Participants With Locally Advanced or Recurrent or Metastatic Non-Small Cell Lung Cancer Who Are Deemed Unsuitable For Platinum-Doublet Chemotherapy
Not yet reported Hoffmann-La Roche 453 participants Est. completion 2023-10-25 91 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT03193190
A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)
Not yet reported, Not yet reported Hoffmann-La Roche 341 participants Est. completion 2025-02-27 23 sites Stand-aloneOther conditions: Pancreatic AdenocarcinomaView official trial listing → -
Withdrawn NCT NCT03196401
A Study of Durvalumab (Anti-PDL1) Plus Radiation Therapy for the Treatment of Solitary Bone Plasmacytoma
Not yet reported Memorial Sloan Kettering Cancer Center Est. completion 2020-06 6 sitesOther conditions: Solitary Bone PlasmacytomaView official trial listing → -
Completed NCT NCT03197935
A Study to Investigate Atezolizumab and Chemotherapy Compared With Placebo and Chemotherapy in the Neoadjuvant Setting in Participants With Early Stage Triple Negative Breast Cancer
Not yet reported Hoffmann-La Roche 333 participants Est. completion 2022-09-28 68 sites Stand-aloneOther conditions: Triple-negative Breast CancerView official trial listing → -
Terminated NCT NCT03199885
Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer
Not yet reported National Cancer Institute (NCI) 190 participants Est. completion 2025-04-04 673 sites Stand-aloneOther conditions: Metastatic Breast Adenocarcinoma, Metastatic HER2-Positive Breast Carcinoma, Recurrent Breast Adenocarcinoma, Recurrent HER2-Positive Breast Carcinoma, Stage III Breast Cancer AJCC v7, Stage IV Breast Cancer AJCC v6 and v7, Unresectable Breast Carcinoma, Unresectable HER2-Positive Breast CarcinomaView official trial listing → -
Completed NCT NCT03201458
Atezolizumab With or Without Cobimetinib in Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed by Surgery or Gallbladder Cancer
Not yet reported National Cancer Institute (NCI) 86 participants Est. completion 2024-02-19 41 sites Stand-aloneOther conditions: Gallbladder Carcinoma, Metastatic Cholangiocarcinoma, Stage III Intrahepatic Cholangiocarcinoma AJCC v8, Stage IV Intrahepatic Cholangiocarcinoma AJCC v8, Unresectable CholangiocarcinomaView official trial listing → -
Active, not recruiting NCT NCT03202316
Atezolizumab, Cobimetinib, and Eribulin in Treating Patients With Chemotherapy Resistant Metastatic Inflammatory Breast Cancer
Not yet reported M.D. Anderson Cancer Center 37 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Recurrent Breast Inflammatory Carcinoma, Stage IV Breast Inflammatory CarcinomaView official trial listing → -
Terminated NCT NCT03206047
Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Not yet reported, Not yet reported National Cancer Institute (NCI) 9 participants Est. completion 2020-11-10 17 sites Stand-aloneOther conditions: Platinum-Resistant Fallopian Tube Carcinoma, Platinum-Resistant Ovarian Carcinoma, Platinum-Resistant Primary Peritoneal Carcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Primary Peritoneal CarcinomaView official trial listing → -
Completed NCT NCT03206203
Carboplatin With or Without Atezolizumab in Treating Patients With Stage IV Triple Negative Breast Cancer
Not yet reported Vanderbilt-Ingram Cancer Center 106 participants Est. completion 2023-10-04 6 sites Stand-aloneOther conditions: Triple Negative Breast Cancer, Stage IV Breast Cancer, HER2 Negative, Invasive Breast CancerView official trial listing → -
Terminated NCT NCT03208712
Radium-223 and Atezolizumab in Patients With Urothelial Carcinoma With Bone Metastases Who Have Had Disease Progression After Platinum-Based Chemotherapy
Not yet reported University of Michigan Rogel Cancer Center 1 participants Est. completion 2018-08-02 1 site Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Completed NCT NCT03212469
A Trial of Durvalumab and Tremelimumab in Combination With SBRT in Patients With Metastatic Cancer
Not yet reported, Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 54 participants Est. completion 2025-02-24 1 siteOther conditions: Head and Neck Squamous Cell Carcinoma, Lung Cancer, Oesophageal CancerView official trial listing → -
Status unknown NCT NCT03228368
The Predicted Potential of Quantitative T Cell Repertoire(TCR) in Anti-PD-L1 Treatment in NSCLC Patients
First Affiliated Hospital of Zhejiang University 10 participants Est. completion 2018-12-01 1 siteOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT03228537
Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma
Not yet reported National Cancer Institute (NCI) 28 participants Est. completion 2027-09-18 174 sites Stand-aloneOther conditions: Biphasic Mesothelioma, Epithelioid Mesothelioma, Stage I Pleural Diffuse Malignant Mesothelioma AJCC v7, Stage IA Pleural Diffuse Malignant Mesothelioma AJCC v7, Stage IB Pleural Diffuse Malignant Mesothelioma AJCC v7, Stage II Pleural Diffuse Malignant Mesothelioma AJCC v7, Stage III Pleural Diffuse Malignant Mesothelioma AJCC v7View official trial listing → -
Active, not recruiting NCT NCT03228667
QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors
Not yet reported ImmunityBio, Inc. 40 participants Est. completion 2030-12-31 35 sites Stand-aloneObstructive sleep apnea Other conditions: Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Urothelial Carcinoma, Head and Neck Squamous Cell Carcinoma, Merkel Cell Carcinoma, Melanoma, Renal Cell Carcinoma, Gastric Cancer, Cervical Cancer, Hepatocellular Carcinoma, Mismatch Repair Deficiency, Colorectal CancerView official trial listing → -
Completed NCT NCT03232593
A Study of Atezolizumab (Tecentriq®) in Ministry of Food and Drug Safety (MFDS)-Approved Indication(s)
Hoffmann-La Roche 1758 participants Est. completion 2022-08-12 56 sitesOther conditions: Urothelial Carcinoma, Carcinoma, Non-Small Cell Lung, Small Cell Lung Carcinoma, Triple Negative Breast Carcinoma, Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03237780
Atezolizumab With or Without Eribulin Mesylate in Treating Patients With Recurrent Locally Advanced or Metastatic Urothelial Cancer
Not yet reported National Cancer Institute (NCI) 72 participants Est. completion 2027-06-30 21 sites Stand-aloneOther conditions: Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis Urothelial Carcinoma, Locally Advanced Ureter Urothelial Carcinoma, Locally Advanced Urethral Urothelial Carcinoma, Metastatic Bladder Urothelial Carcinoma, Metastatic Renal Pelvis Urothelial Carcinoma, Metastatic Ureter Urothelial Carcinoma, Metastatic Urethral Urothelial Carcinoma, Recurrent Bladder Urothelial Carcinoma, Recurrent Renal Pelvis Urothelial Carcinoma, Recurrent Ureter Urothelial Carcinoma, Recurrent Urethral Urothelial Carcinoma, Stage III Bladder Cancer AJCC v8, Stage III Renal Pelvis Cancer AJCC v8, Stage III Ureter Cancer AJCC v8, Stage III Urethral Cancer AJCC v8, Stage IV Bladder Cancer AJCC v8, Stage IV Renal Pelvis Cancer AJCC v8, Stage IV Ureter Cancer AJCC v8, Stage IV Urethral Cancer AJCC v8, Unresectable Bladder Urothelial Carcinoma, Unresectable Renal Pelvis Urothelial Carcinoma, Unresectable Ureter Urothelial Carcinoma, Unresectable Urethral Urothelial CarcinomaView official trial listing → -
Completed NCT NCT03256344
Study of Talimogene Laherparepvec With Atezolizumab for Triple Negative Breast Cancer and Colorectal Cancer With Liver Metastases
Not yet reported Amgen 36 participants Est. completion 2021-12-03 17 sites Stand-aloneOther conditions: Metastatic Triple Negative Breast Cancer, Metastatic Colorectal CancerView official trial listing → -
Status unknown NCT NCT03262454
Sequential Hypofractionated Radiotherapy Followed by Anti-PD-L1 Atezolizumab for SCLC
Not yet reported National Cancer Center, Korea 35 participants Est. completion 2024-07-31 1 site Stand-aloneOther conditions: Small Cell Lung Cancer RecurrentView official trial listing → -
Completed NCT NCT03264066
A Study to Investigate the Efficacy and Safety of Cobimetinib Plus Atezolizumab in Participants With Solid Tumors
Not yet reported Hoffmann-La Roche 87 participants Est. completion 2020-06-25 19 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Terminated NCT NCT03267940
Study of PEGPH20 With Cisplatin (CIS) and Gemcitabine (GEM); PEGPH20 With Atezolizumab (ATEZO), CIS, and GEM; and CIS and GEM Alone in Participants With Previously Untreated, Unresectable, Locally Advanced, or Metastatic Intrahepatic and Extrahepatic Cholangiocarcinoma and Gallbladder Adenocarcinoma
Not yet reported Halozyme Therapeutics 85 participants Est. completion 2019-11-11 36 sites Stand-aloneOther conditions: Cholangiocarcinoma Non-resectable, Cholangiocarcinoma, Intrahepatic, Cholangiocarcinoma, Extrahepatic, Gallbladder AdenocarcinomaView official trial listing → -
Active, not recruiting NCT NCT03271372
Adjuvant Avelumab in Merkel Cell Cancer
Not yet reported University of Washington 101 participants Est. completion 2029-02-18 9 sitesOther conditions: Stage III Merkel Cell Carcinoma AJCC v8, Stage IIIB Merkel Cell Carcinoma AJCC v8, Stage IIIA Merkel Cell Carcinoma AJCC v8View official trial listing → -
Terminated NCT NCT03272217
Atezolizumab With Bevacizumab in Previously Untreated Metastatic/Unresectable Urothelial Cancer
Not yet reported Arjun Balar, MD 16 participants Est. completion 2022-03-17 8 sites Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Terminated NCT NCT03273153
A Study of Cobimetinib Plus Atezolizumab Versus Pembrolizumab in Participants With Previously Untreated Advanced BRAFv600 Wild-Type Melanoma
Not yet reported Hoffmann-La Roche 446 participants Est. completion 2021-02-19 121 sites Stand-aloneOther conditions: Advanced BRAFV600 Wild-type MelanomaView official trial listing → -
Completed NCT NCT03276468
Evaluation of Atezolizumab-Venetoclax-Obinutuzumab Combination in Relapse/Refractory Lymphomas
Not yet reported The Lymphoma Academic Research Organisation 136 participants Est. completion 2022-08-24 25 sites Stand-aloneObstructive sleep apnea Other conditions: Follicular Lymphoma, Diffuse Large B Cell Lymphoma, Marginal Zone LymphomaView official trial listing → -
Completed NCT NCT03280563
A Study of Multiple Immunotherapy-Based Treatment Combinations in Hormone Receptor (HR)-Positive Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer
Not yet reported, Not yet reported Hoffmann-La Roche 144 participants Est. completion 2024-09-26 22 sites Stand-aloneOther conditions: Breast NeoplasmsView official trial listing → -
Terminated NCT NCT03281369
A Study of Multiple Immunotherapy-Based Treatment Combinations in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Cancer (G/GEJ) or Esophageal Cancer (Morpheus-Gastric and Esophageal Cancer)
Not yet reported, Not yet reported Hoffmann-La Roche 219 participants Est. completion 2025-10-09 28 sites Stand-aloneOther conditions: Gastric Adenocarcinoma or Gastroesophageal Junction Adenocarcinoma or Esophageal CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03281954
Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed After Surgery by Atezolizumab or Placebo
Not yet reported NSABP Foundation Inc 1550 participants Est. completion 2027-11-30 217 sites Stand-aloneOther conditions: Triple Negative Breast CancerView official trial listing → -
Completed NCT NCT03285763
A Study of Atezolizumab (Tecentriq) to Investigate Long-term Safety and Efficacy in Previously-treated Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)
Not yet reported Hoffmann-La Roche 619 participants Est. completion 2022-04-07 111 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT03289962
A Study of Autogene Cevumeran (RO7198457) as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Tumors
Not yet reported Genentech, Inc. 273 participants Est. completion 2025-07-01 33 sites Stand-aloneOther conditions: Melanoma, Non-Small Cell Lung Cancer, Bladder Cancer, Colorectal Cancer, Triple Negative Breast Cancer, Renal Cancer, Head and Neck Cancer, Other Solid CancersView official trial listing → -
Terminated NCT NCT03292172
A Study to Evaluate the Safety, Pharmacokinetics and Clinical Activity of RO6870810 and Atezolizumab (PD-L1 Antibody) in Participants With Advanced Ovarian Cancer or Triple Negative Breast Cancer
Not yet reported Hoffmann-La Roche 36 participants Est. completion 2019-02-26 11 sites Stand-aloneOther conditions: Advanced Ovarian Cancer, Triple Negative Breast CancerView official trial listing → -
Completed NCT NCT03312530
A Study of Cobimetinib Administered as Single Agent and in Combination With Venetoclax, With or Without Atezolizumab, in Participants With Relapsed and Refractory Multiple Myeloma
Not yet reported, Not yet reported Hoffmann-La Roche 49 participants Est. completion 2021-05-18 26 sites Stand-aloneOther conditions: Multiple MyelomaView official trial listing → -
Completed NCT NCT03313804
Priming Immunotherapy in Advanced Disease With Radiation
Not yet reported John L. Villano, MD, PhD 76 participants Est. completion 2026-02-16 1 site Stand-aloneOther conditions: Non-small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and NeckView official trial listing → -
Completed NCT NCT03316417
Study of Adverse Renal Effects of Immune Checkpoints Inhibitors
Hospices Civils de Lyon 353 participants Est. completion 2017-10-27 1 siteOther conditions: Adverse Effect, Renal ToxicityView official trial listing → -
Active, not recruiting NCT NCT03321643
Testing the Addition of an Immunotherapy Agent, Atezolizumab, When Given With the Usual Chemo-Immunotherapy Drug Combination (Rituximab Plus Gemcitabine and Oxaliplatin) for Relapsed/Refractory (That Has Come Back or Not Responded to Treatment) Transformed Diffuse Large B-Cell Lymphoma
Not yet reported National Cancer Institute (NCI) 24 participants Est. completion 2027-06-30 4 sites Stand-aloneOther conditions: Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Transformed Non-Hodgkin Lymphoma, Refractory Diffuse Large B-Cell Lymphoma, Refractory Transformed Non-Hodgkin Lymphoma, Richter Syndrome, Transformed Follicular Lymphoma to Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT03321695
A Study of the Safety of Atezolizumab in Participants With Locally Advanced or Metastatic Non Small Cell Lung Cancer in Argentina
Hoffmann-La Roche 44 participants Est. completion 2019-03-02 1 siteOther conditions: Carcinoma, Non-small-cell LungView official trial listing → -
Completed NCT NCT03330886
A Study of the Safety of Atezolizumab in Patients With Advanced or Metastatic Urothelial Carcinoma in Argentina
Hoffmann-La Roche 13 participants Est. completion 2019-03-02 1 siteOther conditions: Urothelial CarcinomaView official trial listing → -
Terminated NCT NCT03337698
A Study Of Multiple Immunotherapy-Based Treatment Combinations In Participants With Metastatic Non-Small Cell Lung Cancer (Morpheus- Non-Small Cell Lung Cancer)
Not yet reported, Not yet reported Hoffmann-La Roche 314 participants Est. completion 2025-11-25 29 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Status unknown NCT NCT03340376
Doxorubicin Alone Versus Atezolizumab Alone Versus Doxorubicin and Atezolizumab in Recurrent Cervical Cancer
Not yet reported Universitaire Ziekenhuizen KU Leuven 48 participants Est. completion 2025-09 1 site Stand-aloneOther conditions: Cervical CancerView official trial listing → -
Withdrawn NCT NCT03340558
Atezolizumab Monotherapy vs Atezolizumab Plus Cobimetinib in Liver Metastases From Colorectal Cancer
Not yet reported Niharika Mettu Est. completion 2025-02 1 site Stand-aloneOther conditions: Metastatic Colorectal CancerView official trial listing → -
Completed NCT NCT03353831
Atezolizumab With Bevacizumab and Chemotherapy vs Bevacizumab and Chemotherapy in Early Relapse Ovarian Cancer
Not yet reported AGO Research GmbH 574 participants Est. completion 2025-03-11 111 sites Stand-aloneOther conditions: Recurrent Ovarian CarcinomaView official trial listing → -
Terminated NCT NCT03357224
PARCT: Trial of Atezolizumab in Relapsed/Refractory Cutaneous T Cell Lymphoma (CTCL)
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC 26 participants Est. completion 2022-08-18 2 sites Stand-aloneOther conditions: Lymphoma, T-Cell, Cutaneous, Mycosis Fungoides/Sezary SyndromeView official trial listing → -
Completed NCT NCT03359239
Atezolizumab Given in Combination With a Personalized Vaccine in Patients With Urothelial Cancer
Not yet reported Matthew Galsky 10 participants Est. completion 2021-10-12 1 site Stand-aloneOther conditions: Urothelial/Bladder Cancer, NosView official trial listing → -
Status unknown NCT NCT03363867
BEACON - ABC in Recurrent Platinum Resistant HGSOC
Not yet reported Peter MacCallum Cancer Centre, Australia 30 participants Est. completion 2025-06-30 1 site Stand-aloneOther conditions: Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal CarcinomaView official trial listing → -
Withdrawn NCT NCT03369964
A Study of Atezolizumab in Combination With an Immunotherapy Agent Investigated With or Without Anti-Cd20 Therapy in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma
Not yet reported Hoffmann-La Roche Est. completion 2019-08-31 2 sites Stand-aloneOther conditions: Lymphoma, Non-HodgkinView official trial listing → -
Completed NCT NCT03371017
A Study of the Efficacy and Safety of Atezolizumab Plus Chemotherapy for Patients With Early Relapsing Recurrent Triple-Negative Breast Cancer
Not yet reported Hoffmann-La Roche 595 participants Est. completion 2024-10-23 124 sites Stand-aloneOther conditions: Triple Negative Breast NeoplasmsView official trial listing → -
Status unknown NCT NCT03371992
Pilot Study of Nilogen 3D-EX and Its Ability to Predict Therapeutic Response to Anti-PD1 or Anti-PDL1 in NSCLC
Not yet reported Nilogen Oncosystems 25 participants Est. completion 2021-06 1 siteOther conditions: Non Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT03386721
Basket Study to Evaluate the Therapeutic Activity of Simlukafusp Alfa as a Combination Therapy in Participants With Advanced and/or Metastatic Solid Tumors
Not yet reported Hoffmann-La Roche 256 participants Est. completion 2021-12-30 44 sites Stand-aloneOther conditions: Advanced/Metastatic Head and Neck, Oesophageal and Cervical CancersView official trial listing → -
Completed NCT NCT03387540
Evaluation of Reporting of Immune Checkpoint Inhibitor Associated Cardio-vascular Adverse Reactions
Groupe Hospitalier Pitie-Salpetriere 104 participants Est. completion 2017-12-31 1 siteOther conditions: Myocarditis, Cardiac ComplicationView official trial listing → -
Completed NCT NCT03390296
OX40, Venetoclax, Avelumab, Glasdegib, Gemtuzumab Ozogamicin, and Azacitidine in Relapsed or Refractory Acute Myeloid Leukemia
Not yet reported, Not yet reported M.D. Anderson Cancer Center 50 participants Est. completion 2022-02-04 1 siteOther conditions: Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03394885
Atezolizumab With Neoadjuvant Chemotherapy for Patients With Newly-Diagnosed Advanced-Stage Ovarian Cancer
Not yet reported, Not yet reported Duke University 18 participants Est. completion 2020-07-20 3 sites Stand-aloneOther conditions: Ovarian Cancer, Ovarian NeoplasmsView official trial listing → -
Completed NCT NCT03395899
Pre-operative Immunotherapy Combination Strategies in Breast Cancer
Not yet reported Queen Mary University of London 71 participants Est. completion 2023-08-18 1 site Stand-aloneOther conditions: Breast Cancer, Estrogen Receptor-positive Breast CancerView official trial listing → -
Status unknown NCT NCT03399071
Study Title: Peri-operative Immuno-Chemotherapy in Operable Oesophageal and Gastric Cancer
Not yet reported Royal Marsden NHS Foundation Trust 44 participants Est. completion 2025-08-15 1 siteOther conditions: Gastric Adenocarcinoma, Oesophageal AdenocarcinomaView official trial listing → -
Terminated NCT NCT03399643
A Study to Investigate The Effectiveness Of Atezolizumab In Patients With Inoperable Locally-Advanced Or Metastatic Urothelial Carcinoma Of The Urinary Tract (Announce)
Hoffmann-La Roche 22 participants Est. completion 2019-01-28 32 sitesOther conditions: Urothelial CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03409016
Biomarkers of Immune-Related Toxicity
University of Colorado, Denver 69 participants Est. completion 2026-10-17 1 siteOther conditions: Cancer, Metastatic CancerView official trial listing → -
Completed NCT NCT03417544
Atezolizumab + Pertuzumab + Trastuzumab In CNS Mets In BC
Not yet reported Nancy Lin, MD 19 participants Est. completion 2026-04-17 2 sites Stand-aloneOther conditions: HER2-positive Metastatic Breast Cancer, Central Nervous System MetastasesView official trial listing → -
Active, not recruiting NCT NCT03421288
Study of Atezolizumab + FLOT vs. FLOT Alone in Patients With GC/GEJ and High Immune Responsiveness
Not yet reported Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 677 participants Est. completion 2027-12-31 2 sites Stand-aloneOther conditions: Gastric Cancer, Gastroesophageal Junction AdenocarcinomaView official trial listing → -
Terminated NCT NCT03422523
Atezolizumab, Rituximab, Gemcitabine and Oxaliplatin in Patients With Relapsed or Refractory DLBCL Not Suitable for High-dose Therapy
Not yet reported University Hospital Southampton NHS Foundation Trust 53 participants Est. completion 2021-11-18 1 site Stand-aloneOther conditions: Diffuse Large B Cell Lymphoma, Relapsed Diffuse Large B-Cell Lymphoma, Refractory Diffuse Large B-Cell LymphomaView official trial listing → -
Completed NCT NCT03430518
Durvalumab and Eribulin in Her2-negative Metastatic Breast Cancer and Recurrent Ovarian Cancer
Not yet reported Amy Tiersten 9 participants Est. completion 2020-02-10 1 siteOther conditions: HER2-Negative Metastatic Breast Cancer, Recurrent Ovarian CancerView official trial listing → -
Completed NCT NCT03434379
A Study of Atezolizumab in Combination With Bevacizumab Compared With Sorafenib in Patients With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma
Not yet reported Hoffmann-La Roche 558 participants Est. completion 2022-11-17 119 sites Stand-aloneOther conditions: Carcinoma, HepatocellularView official trial listing → -
Completed NCT NCT03436563
M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability
Not yet reported, Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2023-08-08 1 siteObstructive sleep apnea Other conditions: Colon Adenocarcinoma, Metastatic Malignant Solid Neoplasm, Rectal Adenocarcinoma, Refractory Colorectal Carcinoma, Stage IV Colon Cancer AJCC v8, Stage IV Rectal Cancer AJCC v8, Stage IVA Colon Cancer AJCC v8, Stage IVA Rectal Cancer AJCC v8, Stage IVB Colon Cancer AJCC v8, Stage IVB Rectal Cancer AJCC v8View official trial listing → -
Completed NCT NCT03438318
Study Evaluating CMP-001 in Combination With Atezolizumab in Participants With Non-Small Cell Lung Cancer
Not yet reported Regeneron Pharmaceuticals 29 participants Est. completion 2019-12-11 5 sites Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT03448835
Neoadjuvant Capecitabine, Oxaliplatin, Docetaxel and Atezolizumab in Resectable Gastric and GE-junction Cancer (PANDA)
Not yet reported The Netherlands Cancer Institute 20 participants Est. completion 2026-10-31 2 sites Stand-aloneOther conditions: Stomach Cancer, Gastro Esophageal Junction CancerView official trial listing → -
Terminated NCT NCT03452137
A Study of Atezolizumab (Anti-PD-L1 Antibody) as Adjuvant Therapy After Definitive Local Therapy in Patients With High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and Neck
Not yet reported Hoffmann-La Roche 406 participants Est. completion 2024-03-06 135 sitesOther conditions: Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)View official trial listing → -
Terminated NCT NCT03455556
Anetumab Ravtansine and Atezolizumab in Treating Participants With Advanced Non-small Cell Lung Cancer
Not yet reported Mayo Clinic 1 participants Est. completion 2020-01-07 3 sites Stand-aloneOther conditions: Mesothelin Positive, Stage III Non-Small Cell Lung Cancer AJCC v7, Stage IIIA Non-Small Cell Lung Cancer AJCC v7, Stage IIIB Non-Small Cell Lung Cancer AJCC v7, Stage IV Non-Small Cell Lung Cancer AJCC v7View official trial listing → -
Completed NCT NCT03456063
A Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer (IMpower030)
Not yet reported Hoffmann-La Roche 453 participants Est. completion 2025-12-31 117 sites Stand-aloneOther conditions: Non-Small-Cell LungView official trial listing → -
Active, not recruiting NCT NCT03463057
The Feasibility and Clinical Efficacy of Atezolizumab Consolidation Treatment in High Risk (IPI > 2) DLBCL
Not yet reported Stichting Hemato-Oncologie voor Volwassenen Nederland 109 participants Est. completion 2027-01 32 sitesOther conditions: NHL, DLBCLView official trial listing → -
Completed NCT NCT03464942
Stereotactic Radiation and Immunotherapy in Patients With Advanced Triple Negative Breast Cancer
Not yet reported Peter MacCallum Cancer Centre, Australia 54 participants Est. completion 2023-06-22 1 siteOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT03465891
Study of the PD-L1 Inhibitor Atezolizumab With or Without Low-dose, Local Radiation in Patients With Relapsed or Refractory Advanced Stage Follicular Lymphoma
Not yet reported Memorial Sloan Kettering Cancer Center 2 participants Est. completion 2019-12-17 6 sites Stand-aloneOther conditions: LymphomaView official trial listing → -
Completed NCT NCT03468426
A Study to Test Different Doses of BI 836880 Combined With Ezabenlimab in Patients With Advanced Non-small Cell Lung Cancer Followed by Other Types of Advanced Solid Tumours
Not yet reported Boehringer Ingelheim 252 participants Est. completion 2024-09-12 43 sites Stand-aloneOther conditions: Non-squamous, Non-Small-Cell Lung Cancer, NeoplasmsView official trial listing → -
Completed NCT NCT03473756
Phase 1b/2 Study of Rogaratinib (BAY1163877) in Combination With Atezolizumab in Urothelial Carcinoma
Not yet reported Bayer 37 participants Est. completion 2024-07-10 30 sites Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03474094
Clinical and Biological Activity of an Anti-PD-L1 (Atezolizumab) in Operable Localised Soft Tissue Sarcomas Patients to be Treated With Radiotherapy
Not yet reported Centre Leon Berard 62 participants Est. completion 2026-12-30 6 sites Stand-aloneOther conditions: Sarcoma,Soft TissueView official trial listing → -
Completed NCT NCT03483012
Atezolizumab + Stereotactic Radiation in Triple-negative Breast Cancer and Brain Metastasis
Not yet reported Dana-Farber Cancer Institute 6 participants Est. completion 2025-11-12 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT03492242
Immune CHeckpoint Inhibitors Monitoring of Adverse Drug ReAction
Groupe Hospitalier Pitie-Salpetriere 1000 participants Est. completion 2018-09-30 1 siteOther conditions: Arthritis, Cancer, Cardiac Disease, Endocrine System Diseases, Autoimmune Diseases, Ophthalmopathy, Myositis, NeuropathyView official trial listing → -
Withdrawn NCT NCT03498222
Study in Patients With Tumours Requiring Arginine to Assess ADI-PEG 20 With Atezolizumab, Pemetrexed and Carboplatin
Not yet reported Queen Mary University of London Est. completion 2021-12-31 Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT03498521
A Phase II Randomized Study Comparing the Efficacy and Safety of Targeted Therapy or Cancer Immunotherapy Versus Platinum-Based Chemotherapy in Patients With Cancer of Unknown Primary Site
Not yet reported Hoffmann-La Roche 529 participants Est. completion 2024-11-07 125 sites Stand-aloneOther conditions: Cancer of Unknown Primary SiteView official trial listing → -
Terminated NCT NCT03498716
A Study Comparing Atezolizumab (Anti PD-L1 Antibody) In Combination With Adjuvant Anthracycline/Taxane-Based Chemotherapy Versus Chemotherapy Alone In Patients With Operable Triple-Negative Breast Cancer
Not yet reported Hoffmann-La Roche 2199 participants Est. completion 2023-08-14 364 sites Stand-aloneOther conditions: Triple Negative Breast CancerView official trial listing → -
Completed NCT NCT03502785
INO-5401 + INO-9012 in Combination With Atezolizumab in Locally Advanced Unresectable or Metastatic/Recurrent Urothelial Carcinoma
Not yet reported, Not yet reported Inovio Pharmaceuticals 35 participants Est. completion 2025-05-09 11 sites Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Completed NCT NCT03511391
CHEckpoint Inhibition in Combination With an Immunoboost of External Beam Radiotherapy in Solid Tumors
Not yet reported University Hospital, Ghent 99 participants Est. completion 2024-01-23 5 sites Stand-aloneOther conditions: Urothelial Carcinoma, Melanoma, Renal Cell Carcinoma, Non-small Cell Lung Cancer, Head and Neck CancerView official trial listing → -
Completed NCT NCT03513952
Atezolizumab and CYT107 in Treating Participants With Locally Advanced, Inoperable, or Metastatic Urothelial Carcinoma
Not yet reported National Cancer Institute (NCI) 47 participants Est. completion 2024-04-01 9 sites Stand-aloneOther conditions: Advanced Bladder Urothelial Carcinoma, Advanced Ureter Urothelial Carcinoma, Metastatic Bladder Urothelial Carcinoma, Metastatic Renal Pelvis Urothelial Carcinoma, Metastatic Ureter Urothelial Carcinoma, Metastatic Urethral Urothelial Carcinoma, Metastatic Urothelial Carcinoma, Recurrent Bladder Urothelial Carcinoma, Recurrent Renal Pelvis Urothelial Carcinoma, Recurrent Ureter Urothelial Carcinoma, Recurrent Urethral Urothelial Carcinoma, Stage III Bladder Cancer AJCC v8, Stage III Renal Pelvis Cancer AJCC v8, Stage III Ureter Cancer AJCC v8, Stage III Urethral Cancer AJCC v8, Stage IV Bladder Cancer AJCC v8, Stage IV Renal Pelvis Cancer AJCC v8, Stage IV Ureter Cancer AJCC v8, Stage IV Urethral Cancer AJCC v8, Stage IVA Bladder Cancer AJCC v8, Stage IVB Bladder Cancer AJCC v8, Unresectable Bladder Urothelial Carcinoma, Unresectable Renal Pelvis Urothelial Carcinoma, Unresectable Ureter Urothelial CarcinomaView official trial listing → -
Completed NCT NCT03519295
A Study of mDCF in Combination or Not With Atezolizumab in Advanced Squamous Cell Anal Carcinoma
Not yet reported GERCOR - Multidisciplinary Oncology Cooperative Group 97 participants Est. completion 2023-09-20 31 sites Stand-aloneOther conditions: Anal CancerView official trial listing → -
Terminated NCT NCT03520686
Nogapendekin Alfa Inbakicept for Advanced Non-Small Cell Lung Cancer
Not yet reported ImmunityBio, Inc. 102 participants Est. completion 2025-10-13 31 sites Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT03524170
Radiation Therapy and M7824 in Treating Patients With Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer
Not yet reported M.D. Anderson Cancer Center 24 participants Est. completion 2022-02-10 1 siteOther conditions: Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8View official trial listing → -
Active, not recruiting NCT NCT03526432
Phase II Study of Atezolizumab + Bevacizumab in Endometrial Cancer
Not yet reported University of Oklahoma 110 participants Est. completion 2026-12 3 sites Stand-aloneOther conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT03526900
Atezolizumab in Combination With Carboplatin Plus Pemetrexed in Chemotherapy-naïve Patients With Asymptomatic Brain Metastasis
Not yet reported Spanish Lung Cancer Group 40 participants Est. completion 2022-09-15 15 sites Stand-aloneOther conditions: Non-small Cell Lung Cancer Stage IVView official trial listing → -
Active, not recruiting NCT NCT03533283
An Open-Label Phase lB/II Study of Glofitamab and Atezolizumab or Polatuzumab Vedotin in Adult Patients With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma
Not yet reported, Not yet reported Hoffmann-La Roche 211 participants Est. completion 2026-10-16 20 sites Stand-aloneOther conditions: Non-Hodgkins LymphomaView official trial listing → -
Active, not recruiting NCT NCT03540420
Atezolizumab After Concurrent Chemo-radiotherapy Versus Chemo-radiotherapy Alone in Limited Disease Small-cell Lung Cancer
Not yet reported Norwegian University of Science and Technology 212 participants Est. completion 2027-04-01 41 sites Stand-aloneOther conditions: Small-cell Lung CancerView official trial listing → -
Status unknown NCT NCT03544723
Safety and Efficacy of p53 Gene Therapy Combined With Immune Checkpoint Inhibitors in Solid Tumors.
Not yet reported MultiVir, Inc. 40 participants Est. completion 2022-12-31 3 sitesOther conditions: Solid Tumor, LymphomaView official trial listing → -
Completed NCT NCT03554083
Vemurafenib, Cobimetinib, Atezolizumab, and Tiragolumab in Treating Patients With High-Risk Stage III Melanoma
Not yet reported Mayo Clinic 64 participants Est. completion 2025-04-30 3 sites Stand-aloneOther conditions: Clinical Stage III Cutaneous Melanoma AJCC v8, Pathologic Stage III Cutaneous Melanoma AJCC v8, Pathologic Stage IIIA Cutaneous Melanoma AJCC v8, Pathologic Stage IIIB Cutaneous Melanoma AJCC v8, Pathologic Stage IIIC Cutaneous Melanoma AJCC v8, Pathologic Stage IIID Cutaneous Melanoma AJCC v8View official trial listing → -
Terminated NCT NCT03555149
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Metastatic Colorectal Cancer (Morpheus-CRC)
Not yet reported, Not yet reported Hoffmann-La Roche 96 participants Est. completion 2022-09-26 15 sites Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Completed NCT NCT03556839
Platinum Chemotherapy Plus Paclitaxel With Bevacizumab and Atezolizumab in Metastatic Carcinoma of the Cervix
Not yet reported Grupo Español de Investigación en Cáncer de Ovario 410 participants Est. completion 2025-08-31 72 sites Stand-aloneOther conditions: Carcinoma of the Cervix, Stage IVBView official trial listing → -
Completed NCT NCT03559647
The Effectiveness Of Atezolizumab In Patients With Locally-Advanced Or Metastatic Non-Small Cell Lung Cancer After Prior Chemotherapy
Hoffmann-La Roche 358 participants Est. completion 2023-08-20 94 sitesOther conditions: Non-Small Cell Lung Cancer (NSCLC)View official trial listing → -
Completed NCT NCT03563716
A Study of Tiragolumab in Combination With Atezolizumab in Chemotherapy-Naïve Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Not yet reported Genentech, Inc. 135 participants Est. completion 2025-11-14 40 sites Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Terminated NCT NCT03566485
Atezolizumab and Cobimetinib or Idasanutlin in Participants With Stage IV or Unresectable Recurrent Estrogen Receptor Positive Breast Cancer
Not yet reported, Not yet reported Vanderbilt-Ingram Cancer Center 12 participants Est. completion 2020-12-10 1 site Stand-aloneOther conditions: Stage III Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer, Estrogen Receptor-positive, HER2/Neu NegativeView official trial listing → -
Completed NCT NCT03568656
Study to Evaluate CCS1477 in Advanced Tumours
Not yet reported, Not yet reported CellCentric Ltd. 219 participants Est. completion 2025-07-06 19 sites Stand-aloneOther conditions: Metastatic Castration-Resistant Prostate Cancer, Metastatic Breast Cancer, Non-small Cell Lung Cancer, Advanced Solid TumorsView official trial listing → -
Status unknown NCT NCT03577132
The Efficacy of Neoadjuvant Atezolizumab Treatment in Patients With Advanced Urothelial Bladder Cancer
Not yet reported Seoul National University Hospital 20 participants Est. completion 2022-05-31 Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Terminated NCT NCT03579472
M7824 and Eribulin Mesylate in Treating Patients With Metastatic Triple Negative Breast Cancer
Not yet reported M.D. Anderson Cancer Center 38 participants Est. completion 2022-09-21 2 sitesOther conditions: Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Triple-Negative Breast Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8View official trial listing → -
Active, not recruiting NCT NCT03595592
Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer
Not yet reported Fondazione Michelangelo 650 participants Est. completion 2027-03-15 65 sites Stand-aloneOther conditions: Invasive Breast CancerView official trial listing → -
Completed NCT NCT03598270
Platinum-based Chemotherapy With Atezolizumab and Niraparib in Patients With Recurrent Ovarian Cancer
Not yet reported Grupo Español de Investigación en Cáncer de Ovario 417 participants Est. completion 2024-08-05 71 sites Stand-aloneOther conditions: Recurrent Ovarian CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03600701
Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer
Not yet reported National Cancer Institute (NCI) 53 participants Est. completion 2026-10-03 18 sites Stand-aloneOther conditions: Metastatic Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Refractory Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8View official trial listing → -
Completed NCT NCT03603184
Atezolizumab Trial in Endometrial Cancer - AtTEnd
Not yet reported Mario Negri Institute for Pharmacological Research 549 participants Est. completion 2025-01-20 93 sites Stand-aloneOther conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT03612791
Trial Assessing the Inhibitor of Programmed Cell Death Ligand 1 (PD-L1) Immune Checkpoint Atezolizumab
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 189 participants Est. completion 2025-05-13 1 site Stand-aloneOther conditions: Locally Advanced Cervical CancerView official trial listing → -
Active, not recruiting NCT NCT03614949
SBRT and Atezolizumab in the Management of Recurrent, Persistent, or Metastatic Cervical Cancer
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 21 participants Est. completion 2028-10 2 sites Stand-aloneOther conditions: Cervical Cancer, Cervical Cancer Recurrent, Cervical Cancer MetastaticView official trial listing → -
Status unknown NCT NCT03616691
Atezolizumab Monotherapy and Consequent Therapy With Atezolizumab Plus Bevacizumab for NSCLC
Not yet reported Samsung Medical Center 46 participants Est. completion 2020-06-30 Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT03618953
This is a Trial of MG1-E6E7 With Ad-E6E7 and Atezolizumab in Patients With HPV Associated Cancers
Not yet reported Turnstone Biologics, Corp. 8 participants Est. completion 2021-03-05 8 sites Stand-aloneOther conditions: HPV-Associated CancersView official trial listing → -
Completed NCT NCT03620201
M7824 in Treating Patients With Stage II-III HER2 Positive Breast Cancer
Not yet reported M.D. Anderson Cancer Center 20 participants Est. completion 2024-10-18 1 siteOther conditions: Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8, Anatomic Stage IIB Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Prognostic Stage II Breast Cancer AJCC v8, Prognostic Stage IIA Breast Cancer AJCC v8, Prognostic Stage IIB Breast Cancer AJCC v8, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8View official trial listing → -
Status unknown NCT NCT03620435
Trimodal Therapy Plus Atezolizumab in Muscle-invasive Bladder Cancer
Not yet reported McGill University Health Centre/Research Institute of the McGill University Health Centre 25 participants Est. completion 2020-12-30 1 site Stand-aloneOther conditions: Safety IssuesView official trial listing → -
Completed NCT NCT03625141
A Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases
Not yet reported Hoffmann-La Roche 80 participants Est. completion 2023-04-13 22 sites Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Completed NCT NCT03628716
CV301 Combined With PD-1/L1 Blockade in Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer
Not yet reported Bavarian Nordic 43 participants Est. completion 2021-02-02 6 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Terminated NCT NCT03637764
Safety, Preliminary Efficacy and PK of Isatuximab (SAR650984) Alone or in Combination With Atezolizumab in Patients With Advanced Malignancies
Not yet reported, Not yet reported Sanofi 107 participants Est. completion 2022-05-11 26 sites Stand-aloneOther conditions: NeoplasmView official trial listing → -
Terminated NCT NCT03644823
Combinatory ImmunoTherapy-1 (Com-IT-1) Irradiation and PD-1 Blockade in Locally Advanced / Advanced NSCLC
Not yet reported Oslo University Hospital 21 participants Est. completion 2020-12-31 1 site Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT03645330
A Study of Atezolizumab in Patients With Unresectable, Locally Advanced or Metastatic NSCLC (J-TAIL)
Chugai Pharmaceutical 1026 participants Est. completion 2021-07-08 198 sitesOther conditions: Non-small-Cell Lung CancerView official trial listing → -
Status unknown NCT NCT03647956
Atezolizumab in Combination With Bevacizumab, Carboplatin and Pemetrexed for EGFR-mutant Metastatic NSCLC Patients After Failure of EGFR Tyrosine Kinase Inhibitors
Not yet reported The University of Hong Kong 40 participants Est. completion 2020-04-03 1 site Stand-aloneOther conditions: NSCLC Stage IIIB, NSCLC Stage IV, EGFR Activating MutationView official trial listing → -
Completed NCT NCT03650348
PRS-343 in Combination With Atezolizumab in HER2-Positive Solid Tumors
Not yet reported Pieris Pharmaceuticals, Inc. 41 participants Est. completion 2022-08-11 8 sites Stand-aloneOther conditions: HER2-positive Breast Cancer, HER2-positive Gastric Cancer, HER2-positive Bladder Cancer, HER2-positive Solid TumorView official trial listing → -
Completed NCT NCT03654833
Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant Mesothelioma
Not yet reported University of Leicester 186 participants Est. completion 2024-03-15 1 site Stand-aloneOther conditions: Mesothelioma, MalignantView official trial listing → -
Active, not recruiting NCT NCT03673787
A Trial of Ipatasertib in Combination With Atezolizumab
Not yet reported, Not yet reported Institute of Cancer Research, United Kingdom 87 participants Est. completion 2026-03 1 site Stand-aloneOther conditions: Solid Tumor, Glioblastoma Multiforme, Prostate Cancer MetastaticView official trial listing → -
Completed NCT NCT03686332
PEnile Cancer Radio- and Immunotherapy CLinical Exploration Study
Not yet reported The Netherlands Cancer Institute 32 participants Est. completion 2023-09-15 1 siteOther conditions: Penile CancerView official trial listing → -
Completed NCT NCT03689855
Ramucirumab and Atezolizumab After Progression on Any Immune Checkpoint Blocker in NSCLC
Not yet reported Washington University School of Medicine 21 participants Est. completion 2024-04-22 1 site Stand-aloneOther conditions: Non-small Cell Lung Cancer, Non Small Cell Lung Cancer, NSCLCView official trial listing → -
Active, not recruiting NCT NCT03693014
A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors
Not yet reported Memorial Sloan Kettering Cancer Center 69 participants Est. completion 2027-10 10 sites Stand-aloneOther conditions: Metastatic Cancer, Melanoma Cancer, Lung Cancer, Bladder Cancer, Renal Cancer, Head/Neck CancersView official trial listing → -
Withdrawn NCT NCT03693573
A Study of Atezolizumab in Combination With Bevacizumab in Untreated Locally Advanced or Metastatic Clear Cell or Non-Clear Cell Renal Cell Carcinoma
Not yet reported Hoffmann-La Roche Est. completion 2024-01-31 Stand-aloneOther conditions: Renal Cell CarcinomaView official trial listing → -
Completed NCT NCT03694262
The EndoBARR Trial (Endometrial Bevacizumab, Atezolizumab, Rucaparib)
Not yet reported Medical College of Wisconsin 30 participants Est. completion 2026-03-10 3 sites Stand-aloneObstructive sleep apnea Other conditions: Endometrial CancerView official trial listing → -
Completed NCT NCT03695380
A Clinical Study of Cobimetinib Administered in Combination With Niraparib, With or Without Atezolizumab to Patients With Advanced Platinum-sensitive Ovarian Cancer
Not yet reported Hoffmann-La Roche 77 participants Est. completion 2023-07-12 20 sites Stand-aloneOther conditions: OVARIAN CANCERView official trial listing → -
Active, not recruiting NCT NCT03697850
Atezolizumab After Chemo-radiotherapy for MIBC Patients Not Eligible for Radical Cystectomy
Not yet reported UNICANCER 79 participants Est. completion 2029-02-15 12 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT03698461
Treatment of Colorectal Liver Metastases With Immunotherapy and Bevacizumab
Not yet reported Asan Medical Center 20 participants Est. completion 2023-10-24 1 site Stand-aloneOther conditions: Colorectal Neoplasms, Neoplasm Metastasis, Colonic Neoplasms, Rectal NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT03708224
Preoperative Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck
Not yet reported Alain Algazi 55 participants Est. completion 2027-07-31 1 site Stand-aloneOther conditions: Cancer, Carcinoma, Squamous Cell Carcinoma, Head and Neck CancerView official trial listing → -
Terminated NCT NCT03713944
Carboplatin Plus Pemetrexed Plus Atezolizumab Plus Bevacizumab in Chemotherapy and Immunotherapy-naïve Patients With Stage IV Non-squamous Non-small Cell Lung Cancer
Not yet reported Nasser Hanna 30 participants Est. completion 2021-12-16 7 sites Stand-aloneOther conditions: NSCLC Stage IV, NSCLC, RecurrentView official trial listing → -
Completed NCT NCT03721653
FOLFOXIRI + Bev + Atezo vs FOLFOXIRI + Bev as First-line Treatment of Unresectable Metastatic Colorectal Cancer Patients
Not yet reported Gruppo Oncologico del Nord-Ovest 218 participants Est. completion 2023-08-31 1 site Stand-aloneOther conditions: Metastatic Colorectal CancerView official trial listing → -
Terminated NCT NCT03721679
Poly-ICLC (Hiltonol) and Anti-PD1 or Anti-PD-L1
Not yet reported, Not yet reported Oncovir, Inc. 7 participants Est. completion 2021-01-26 3 sites Stand-aloneOther conditions: Solid CancerView official trial listing → -
Completed NCT NCT03726879
A Study To Evaluate the Efficacy and Safety Of Atezolizumab or Placebo in Combination With Neoadjuvant Doxorubicin + Cyclophosphamide Followed By Paclitaxel + Trastuzumab + Pertuzumab In Early Her2-Positive Breast Cancer
Not yet reported Hoffmann-La Roche 454 participants Est. completion 2023-08-24 76 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT03730012
A Study of ASP2215 (Gilteritinib) Combined With Atezolizumab in Patients With Relapsed or Treatment Refractory FMS-like Tyrosine Kinase (FLT3) Mutated Acute Myeloid Leukemia (AML)
Not yet reported, Not yet reported Astellas Pharma Global Development, Inc. 11 participants Est. completion 2021-06-15 12 sites Stand-aloneOther conditions: Acute Myeloid Leukemia (AML), Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) MutationView official trial listing → -
Completed NCT NCT03735121
A Study to Investigate Atezolizumab Subcutaneous in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 438 participants Est. completion 2024-11-11 74 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT03737123
Trial of Atezolizumab Plus Chemotherapy After Progression on PD-1 or PD-L1 in Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma
Not yet reported Nabil Adra 6 participants Est. completion 2022-05-18 4 sites Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Completed NCT NCT03738228
Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer
Not yet reported National Cancer Institute (NCI) 40 participants Est. completion 2025-09-12 16 sites Stand-aloneOther conditions: Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Stage IB2 Cervical Cancer AJCC v8, Stage II Cervical Cancer AJCC v8, Stage IIA Cervical Cancer AJCC v8, Stage IIA1 Cervical Cancer AJCC v8, Stage IIA2 Cervical Cancer AJCC v8, Stage IIB Cervical Cancer AJCC v8, Stage IIIB Cervical Cancer AJCC v8, Stage IVA Cervical Cancer AJCC v8View official trial listing → -
Active, not recruiting NCT NCT03755791
Study of Cabozantinib in Combination With Atezolizumab Versus Sorafenib in Participants With Advanced Hepatocellular Carcinoma (HCC) Who Have Not Received Previous Systemic Anticancer Therapy
Not yet reported Exelixis 837 participants Est. completion 2026-07-31 245 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03756298
Efficacy and Safety of Atezolizumab Plus Capecitabine Adjuvant Therapy for Triple Receptor-Negative Breast Cancer
Not yet reported National Cancer Center, Korea 284 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Triple Negative Breast CancerView official trial listing → -
Completed NCT NCT03762018
BEAT-meso: Bevacizumab and Atezolizumab in Malignant Pleural Mesothelioma
Not yet reported ETOP IBCSG Partners Foundation 400 participants Est. completion 2024-11-18 42 sites Stand-aloneOther conditions: Pleural Mesothelioma Malignant AdvancedView official trial listing → -
Active, not recruiting NCT NCT03768063
A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study
Not yet reported Hoffmann-La Roche 1000 participants Est. completion 2028-07-05 80 sites Stand-aloneOther conditions: CancerView official trial listing → -
Active, not recruiting NCT NCT03775265
Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer
Not yet reported National Cancer Institute (NCI) 475 participants Est. completion 2027-06-01 365 sites Stand-aloneOther conditions: Bladder Urothelial Carcinoma, Muscle Invasive Bladder Carcinoma, Stage II Bladder Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8View official trial listing → -
Completed NCT NCT03782207
A Study Investigating the Outcomes and Safety of Atezolizumab Under Real-World Conditions in Patients Treated in Routine Clinical Practice
Hoffmann-La Roche 2756 participants Est. completion 2026-07-31 257 sitesOther conditions: Urothelial Carcinoma, Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03784326
Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma
Not yet reported M.D. Anderson Cancer Center 43 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8, Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IIB Esophageal Adenocarcinoma AJCC v8, Clinical Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage III Esophageal Adenocarcinoma AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8, Pathologic Stage IB Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IB Gastroesophageal Junction Adenocarcinoma AJCC v8, Pathologic Stage IC Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IC Gastroesophageal Junction Adenocarcinoma AJCC v8, Pathologic Stage II Esophageal Adenocarcinoma AJCC v8, Pathologic Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8, Pathologic Stage IIA Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8, Pathologic Stage IIB Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IIB Gastroesophageal Junction Adenocarcinoma AJCC v8, Pathologic Stage III Esophageal Adenocarcinoma AJCC v8, Pathologic Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8, Pathologic Stage IIIA Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IIIA Gastroesophageal Junction Adenocarcinoma AJCC v8, Pathologic Stage IIIB Esophageal Adenocarcinoma AJCC v8, Pathologic Stage IIIB Gastroesophageal Junction Adenocarcinoma AJCC v8View official trial listing → -
Withdrawn NCT NCT03786419
A Study of Atezolizumab in Unresectable or Advaced Malignant Pleural Mesothelioma
Not yet reported Health Pharma Professional Research Est. completion 2020-08 1 site Stand-aloneOther conditions: Malignant Pleural Mesothelioma, Advanced, Malignant Pleural Mesothelioma, UnresectableView official trial listing → -
Active, not recruiting NCT NCT03786692
Phase II Randomized Trial of Carboplatin+Pemetrexed+Bevacizumab+/- Atezolizumab in Stage IV NSCLC
Not yet reported Fox Chase Cancer Center 107 participants Est. completion 2028-01 1 site Stand-aloneOther conditions: Non-Small Cell Carcinoma of Lung, TNM Stage 4View official trial listing → -
Completed NCT NCT03790397
Osimertinib in Subjects With Advanced Non-Small Cell Lung Cancer EGFR-T790M Mutation-positive
Fundación GECP 169 participants Est. completion 2020-04-01 31 sitesOther conditions: Non Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT03799835
Atezolizumab Plus One-year BCG Bladder Instillation in BCG-naive High-risk Non-muscle Invasive Bladder Cancer Patients
Not yet reported UNICANCER 517 participants Est. completion 2028-10 38 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT03800836
A Study to Evaluate the Safety and Efficacy of Ipatasertib in Combination With Atezolizumab and Paclitaxel or Nab-Paclitaxel in Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer
Not yet reported Hoffmann-La Roche 139 participants Est. completion 2022-03-16 18 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT03801304
Trial to Evaluate Safety and Efficacy of Vinorelbine With Metronomic Administration in Combination With Atezolizumab as Second-line Treatment for Patients With Stage IV Non-small Cell Lung Cancer
Not yet reported University Hospital, Brest 80 participants Est. completion 2022-02-23 13 sites Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT03802604
Combination of Talimogene Laherparepvec With Atezolizumab in Early Breast Cancer
Not yet reported SOLTI Breast Cancer Research Group 28 participants Est. completion 2025-03-18 4 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Active, not recruiting NCT NCT03811002
Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC)
Not yet reported National Cancer Institute (NCI) 544 participants Est. completion 2029-02-21 542 sites Stand-aloneOther conditions: Limited Stage Lung Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8View official trial listing → -
Completed NCT NCT03818061
Atezolizumab and Bevacizumab in Patients With Recurrent or Metastatic Squamous-cell Carcinoma of the Head and Neck
Not yet reported Centre Leon Berard 33 participants Est. completion 2025-01-15 7 sites Stand-aloneOther conditions: Head and Neck NeoplasmsView official trial listing → -
Withdrawn NCT NCT03818997
Combination of Targeted and Immunotherapy for Advanced Biliary Tract and Esophagogastric Gastric Cancer
Not yet reported European Organisation for Research and Treatment of Cancer - EORTC Est. completion 2022-04 Stand-aloneOther conditions: Esophageal Cancer, Biliary Tract Cancer, GastroEsophageal Cancer, Hepatobiliary NeoplasmView official trial listing → -
Terminated NCT NCT03829501
A Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced Malignancies
Not yet reported, Not yet reported Kymab Limited 222 participants Est. completion 2024-10-03 22 sites Stand-aloneOther conditions: Squamous Cell Carcinoma of Head and Neck, Non-small Cell Lung Cancer, Hepatocellular Carcinoma, Esophageal Cancer, Gastric Cancer, Melanoma, Renal Cell Carcinoma, Pancreatic Cancer, Cervical Cancer, Triple Negative Breast Cancer, Advanced Cancer, Metastatic CancerView official trial listing → -
Active, not recruiting NCT NCT03830918
Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy
Not yet reported, Not yet reported Jonsson Comprehensive Cancer Center 59 participants Est. completion 2027-01-03 1 site Stand-aloneOther conditions: Advanced Malignant Solid Neoplasm, Extensive Stage Lung Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8View official trial listing → -
Status unknown NCT NCT03835949
Study of TJ004309 in Combination With Atezolizumab (Tecentriq®) in Patients With Advanced or Metastatic Cancer
Not yet reported Tracon Pharmaceuticals Inc. 36 participants Est. completion 2022-06 4 sites Stand-aloneOther conditions: Solid Tumor, Metastatic CancerView official trial listing → -
Completed NCT NCT03836066
Atezolizumab Plus Bevacizumab in First Line NSCLC Patients
Not yet reported Fundación GECP 41 participants Est. completion 2024-10-21 25 sites Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT03841110
FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors
Not yet reported Fate Therapeutics 37 participants Est. completion 2022-11-15 4 sites Stand-aloneObstructive sleep apnea Other conditions: Advanced Solid Tumors, Lymphoma, Gastric Cancer, Colorectal Cancer, Head and Neck Cancer, Squamous Cell Carcinoma, EGFR Positive Solid Tumor, HER2-positive Breast Cancer, Hepatocellular Carcinoma, Small Cell Lung Cancer, Renal Cell Carcinoma, Pancreas Cancer, Melanoma, NSCLC, Urothelial Carcinoma, Cervical Cancer, Merkel Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT03845166
A Study of XL092 as Single-Agent and Combination Therapy in Subjects With Solid Tumors
Not yet reported Exelixis 325 participants Est. completion 2027-05-31 86 sites Stand-aloneOther conditions: Neoplasm Malignant, Renal Cell Carcinoma, Hormone Receptor Positive Breast Carcinoma, Metastatic Castration-resistant Prostate Cancer, Colorectal CancerView official trial listing → -
Withdrawn NCT NCT03850028
Molecular Imaging Using Radiolabeled Atezolizumab to Assess Atezolizumab Biodistribution in Lymphoma Patients
Not yet reported University Medical Center Groningen Est. completion 2022-05-01 2 sitesOther conditions: Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedView official trial listing → -
Completed NCT NCT03853707
Ipatasertib in Combination With Carboplatin, Carboplatin/Paclitaxel, or Capecitabine/Atezolizumab in Treating Patients With Metastatic Triple Negative Breast Cancer
Not yet reported, Not yet reported City of Hope Medical Center 28 participants Est. completion 2023-09-19 1 site Stand-aloneOther conditions: Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Triple-Negative Breast Carcinoma, Prognostic Stage IV Breast Cancer AJCC v8View official trial listing → -
Terminated NCT NCT03866239
A Phase Ib Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Cibisatamab in Combination With Atezolizumab After Pretreatment With Obinutuzumab in Participants With Previously Treated Metastatic Colorectal Adenocarcinoma
Not yet reported Hoffmann-La Roche 47 participants Est. completion 2024-03-13 13 sites Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Completed NCT NCT03868046
Autoantibodies in Treatment with Immune Checkpoint Inhibitors (AUTENTIC)
Hospital Universitario Araba 242 participants Est. completion 2023-12-31 1 siteOther conditions: Cancer, Metastatic Cancer, Solid Organ CancerView official trial listing → -
Terminated NCT NCT03869190
Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)
Not yet reported, Not yet reported Hoffmann-La Roche 272 participants Est. completion 2025-12-22 33 sites Stand-aloneOther conditions: Urothelial Carcinoma, Bladder CancerView official trial listing → -
Status unknown NCT NCT03881878
TAHP for Patients With HER2-positive Early Breast Cancer and Subsequent AHP Adjuvant tHerapy After Surgery
Not yet reported, Not yet reported Samsung Medical Center 67 participants Est. completion 2022-10-31 1 site Stand-aloneOther conditions: HER2-positive Breast CancerView official trial listing → -
Terminated NCT NCT03892525
Study of Intratumoral Selicrelumab With Atezolizumab in Patients With Refractory or Relapsed B Cell Lymphoma
Not yet reported The Lymphoma Academic Research Organisation 4 participants Est. completion 2021-04-07 5 sites Stand-aloneOther conditions: Recurrent B-Cell Non-Hodgkin Lymphoma, Refractory B-Cell Non-Hodgkin LymphomaView official trial listing → -
Terminated NCT NCT03894007
Improving Pre-operative Systemic Therapy for Human Epidermal Growth Factor Receptor 2 (HER2) Amplified Breast Cancer
Not yet reported Renske Altena 6 participants Est. completion 2021-06-30 8 sites Stand-aloneOther conditions: Early-stage Breast Cancer, HER2-positive Breast CancerView official trial listing → -
Active, not recruiting NCT NCT03896074
Atezolizumab Versus Atezolizumab Plus Bevacizumab as First Line in NSCLC Patients (BEAT)
Not yet reported Fondazione Ricerca Traslazionale 206 participants Est. completion 2027-05 33 sites Stand-aloneOther conditions: Non-small-cell Lung Cancer PatientsView official trial listing → -
Terminated NCT NCT03901573
High-Risk Skin Cancers With Atezolizumab Plus NT-I7
Not yet reported, Not yet reported NeoImmuneTech 31 participants Est. completion 2023-08-15 8 sites Stand-aloneOther conditions: Melanoma, Merkel Cell Carcinoma, Cutaneous Squamous Cell CarcinomaView official trial listing → -
Completed NCT NCT03911219
Impact of eHealth Monitoring on Overall Survival in Patients With Metastatic NSCLC / Extensive-stage SCLC / Advanced TNBC Under First-line Treatment With Atezolizumab Plus Chemotherapy
iOMEDICO AG 154 participants Est. completion 2021-07-01 92 sitesOther conditions: Stage IV Non-small Cell Lung Cancer, Extensive-stage Small Cell Lung Cancer, Advanced (Locally Advanced and Inoperable or Metastatic), PD-L1 IC-positive TNBCView official trial listing → -
Active, not recruiting NCT NCT03915678
Atezolizumab Combined With BDB001 AnD Immunogenic Radiotherapy in Patients With Advanced Solid Tumors
Not yet reported Institut Bergonié 247 participants Est. completion 2027-12 11 sites Stand-aloneOther conditions: Solid Tumor, Adult, Pancreatic Cancer, Virus-associated Tumors, Non Small Cell Lung Cancer, Melanoma, Bladder Cancer, Triple Negative Breast CancerView official trial listing → -
Terminated NCT NCT03922477
A Study Evaluating the Safety and Pharmacokinetics of Atezolizumab Administered in Combination With Hu5F9-G4 to Patients With Relapsed and/or Refractory Acute Myeloid Leukemia
Not yet reported Hoffmann-La Roche 13 participants Est. completion 2020-11-03 4 sites Stand-aloneOther conditions: Acute Myeloid LeukemiaView official trial listing → -
Completed NCT NCT03922997
A Study to Investigate the Safety and Efficacy of Atezolizumab in Previously-Treated Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 101 participants Est. completion 2022-08-11 7 sites Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT03946358
Combination of UCPVax Vaccine and Atezolizumab for the Treatment of Human Papillomavirus Positive Cancers (VolATIL)
Not yet reported Centre Hospitalier Universitaire de Besancon 47 participants Est. completion 2024-11-01 4 sites Stand-aloneOther conditions: Squamous Cell Carcinoma of the Head and Neck, Anal Canal Cancer, Cervical CancerView official trial listing → -
Terminated NCT NCT03952325
Tesetaxel Plus 3 Different PD-(L)1 Inhibitors in Patients With Triple-Negative MBC and Tesetaxel Monotherapy in Patients With HER2-Negative MBC
Not yet reported Odonate Therapeutics, Inc. 294 participants Est. completion 2021-06-23 12 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT03961698
Evaluation of IPI-549 Combined With Front-line Treatments in Pts. With Triple-Negative Breast Cancer or Renal Cell Carcinoma
Not yet reported Infinity Pharmaceuticals, Inc. 91 participants Est. completion 2023-08-31 24 sites Stand-aloneOther conditions: Breast Cancer, Renal Cell CarcinomaView official trial listing → -
Withdrawn NCT NCT03973333
Safety and Efficacy of IMC-C103C as Monotherapy and in Combination With Atezolizumab
Not yet reported, Not yet reported Immunocore Ltd Est. completion 2023-09-25 19 sites Stand-aloneOther conditions: Select Advanced Solid TumorsView official trial listing → -
Withdrawn NCT NCT03973879
Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Glioma
Not yet reported, Not yet reported Darell Bigner Est. completion 2024-01 Stand-aloneOther conditions: Malignant GliomaView official trial listing → -
Completed NCT NCT03976518
Atezolizumab in Advanced Non-small Cell Lung Cancer With Rare Histologies (CHANCE Trial)
Not yet reported Gruppo Oncologico Italiano di Ricerca Clinica 43 participants Est. completion 2024-02-12 10 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT03977194
Atezolizumab in Elderly Patients With Advanced Non-Small-Cell Lung Cancer and Receiving Carboplatin Paclitaxel Chemotherapy
Not yet reported Intergroupe Francophone de Cancerologie Thoracique 510 participants Est. completion 2026-12 68 sites Stand-aloneOther conditions: Non Small Cell Lung Cancer MetastaticView official trial listing → -
Completed NCT NCT03977467
Atezolizumab and Tiragolumab in Patients With NSCLC or Advanced Solid Tumors Having Had Prior Treatment With a PD-1 Inhibitor
Not yet reported SCRI Development Innovations, LLC 46 participants Est. completion 2024-08-09 7 sites Stand-aloneOther conditions: Non-Small Cell Lung Cancer, Solid TumorView official trial listing → -
Terminated NCT NCT03979066
Study Evaluating NEOadjuvant Immunotherapy in Resectable PANCreatic Ductal Adenocarcinoma
Not yet reported Gulam Manji 1 participants Est. completion 2019-11-03 1 site Stand-aloneOther conditions: Pancreatic Ductal AdenocarcinomaView official trial listing → -
Withdrawn NCT NCT03982173
Basket Trial for Combination Therapy With Durvalumab (Anti-PDL1) (MEDI4736) and Tremelimumab (Anti-CTLA4) in Patients With Metastatic Solid Tumors
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris Est. completion 2024-12-05Other conditions: Metastatic Colorectal Cancer, Triple Negative Breast Cancer, Prostate Adenocarcinoma, Stomach Adenocarcinoma, Esophageal AdenocarcinomaView official trial listing → -
Status unknown NCT NCT03991403
Study of Atezolizumab Combination Carboplatin + Paclitaxel + Bevacizumab in EGRF Mutation or ALK Translocation NSCLC
Not yet reported Samsung Medical Center 228 participants Est. completion 2024-03-11 1 site Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT04006522
89Zr-DFO-Atezolizumab ImmunoPET/CT in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma
Not yet reported James Brugarolas 46 participants Est. completion 2027-08-31 1 site Stand-aloneOther conditions: Renal Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT04017455
Neoadjuvant Treatment in Rectal Cancer With Radiotherapy Followed by Atezolizumab and Bevacizumab (TARZAN)
Not yet reported The Netherlands Cancer Institute 38 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Rectal CancerView official trial listing → -
Withdrawn NCT NCT04020094
Perioperative Atezolizumab With MVA-BN-Brachyury and PROSTVAC For Intermediate-Risk And High-Risk Localized Prostate Cancer
Not yet reported University of Utah Est. completion 2021-04-09 1 site Stand-aloneOther conditions: Prostate AdenocarcinomaView official trial listing → -
Active, not recruiting NCT NCT04020809
Neoadjuvant Atezolizumab in Cutaneous Melanoma
Not yet reported The Methodist Hospital Research Institute 20 participants Est. completion 2026-10-01 1 site Stand-aloneOther conditions: Cutaneous MelanomaView official trial listing → -
Completed NCT NCT04028050
A Study of Atezolizumab in Combination With Carboplatin Plus Etoposide to Investigate Safety and Efficacy in Patients With Untreated Extensive-Stage Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 155 participants Est. completion 2023-07-13 25 sites Stand-aloneOther conditions: Small Cell Lung CarcinomaView official trial listing → -
Status unknown NCT NCT04029181
ImmunoPET With an Anti-CD8 Imaging Agent
Not yet reported, Not yet reported University Medical Center Groningen 47 participants Est. completion 2024-12 1 siteOther conditions: Metastatic Cancer, Unresectable Malignant NeoplasmView official trial listing → -
Completed NCT NCT04042558
A Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/-Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung Cancer With EGFR Mutations, ALK Rearrangement or ROS1 Fusion Progressing After Targeted Therapies
Not yet reported Centre Francois Baclesse 150 participants Est. completion 2025-04-09 31 sites Stand-aloneOther conditions: NSCLC Stage IIIB, NSCLC Stage IV, EGFR Gene Mutation, ALK Gene Rearrangement Positive, ROS1 Gene MutationView official trial listing → -
Terminated NCT NCT04045028
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Preliminary Activity of Tiragolumab in Participants With Relapsed or Refractory Multiple Myeloma or With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Not yet reported Genentech, Inc. 41 participants Est. completion 2023-03-28 14 sites Stand-aloneOther conditions: Multiple Myeloma, Non-Hodgkin Lymphoma, B-Cell LymphomaView official trial listing → -
Completed NCT NCT04045613
Derazantinib and Atezolizumab in Patients With Urothelial Cancer
Not yet reported, Not yet reported Basilea Pharmaceutica 95 participants Est. completion 2022-10-04 66 sites Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Completed NCT NCT04059887
Evaluation of Blood TMB for the Efficacy of Atezolizumab [BUDDY]
Not yet reported Chonnam National University Hospital 100 participants Est. completion 2022-06-30 1 site Stand-aloneOther conditions: Lung Neoplasm MalignantView official trial listing → -
Terminated NCT NCT04081688
Atezolizumab and Varlilumab in Combination With Radiation Therapy for NSCLC
Not yet reported Rutgers, The State University of New Jersey 16 participants Est. completion 2024-04-30 1 site Stand-aloneOther conditions: Refractory Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8View official trial listing → -
Active, not recruiting NCT NCT04082897
ObinutuzuMab AtezOlizumab and VenetocLax in RichTer transfOrmation
Not yet reported Niguarda Hospital 28 participants Est. completion 2026-12 17 sites Stand-aloneOther conditions: CLL TransformationView official trial listing → -
Completed NCT NCT04084951
Study of SQZ-PBMC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors
Not yet reported SQZ Biotechnologies 30 participants Est. completion 2023-02-09 12 sites Stand-aloneOther conditions: Adult Solid TumorView official trial listing → -
Completed NCT NCT04091217
Atezolizumab in Combination With Bevacizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal Melanoma
Not yet reported Hoffmann-La Roche 43 participants Est. completion 2023-09-01 3 sites Stand-aloneOther conditions: MelanomaView official trial listing → -
Completed NCT NCT04096638
Safety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors
Not yet reported invoX Pharma Limited 61 participants Est. completion 2024-07-16 2 sites Stand-aloneOther conditions: Melanoma, Head and Neck Squamous Cell Carcinoma, Solid TumorView official trial listing → -
Terminated NCT NCT04099836
Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving Osimertinib
Not yet reported Duke University 7 participants Est. completion 2023-06-15 1 site Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT04101357
Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411
Not yet reported, Not yet reported BioNTech SE 54 participants Est. completion 2024-05-23 12 sites Stand-aloneOther conditions: Solid Tumor, Extensive-stage Small Cell Lung CancerView official trial listing → -
Completed NCT NCT04102098
A Study of Atezolizumab Plus Bevacizumab Versus Active Surveillance as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Surgical Resection or Ablation
Not yet reported Hoffmann-La Roche 668 participants Est. completion 2026-05-15 134 sites Stand-aloneOther conditions: Carcinoma, HepatocellularView official trial listing → -
Terminated NCT NCT04102618
A Window-of-opportunity Study of Pelareorep in Early Breast Cancer
Not yet reported Oncolytics Biotech 26 participants Est. completion 2022-04-20 14 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Status unknown NCT NCT04107168
Microbiome Immunotherapy Toxicity and Response Evaluation
CCTU- Cancer Theme 1800 participants Est. completion 2025-07-08 13 sitesOther conditions: Melanoma, Renal Cancer, Lung CancerView official trial listing → -
Terminated NCT NCT04108481
Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer
Not yet reported University of Iowa 5 participants Est. completion 2023-11-17 1 siteOther conditions: Colorectal Cancer Metastatic, Colon Cancer, Metastatic Colorectal Cancer, Rectal Cancer, Liver Metastasis Colon Cancer, Colo-rectal Cancer, Colorectal Adenocarcinoma, Colorectal Neoplasms, Liver Metastases, Colorectal CarcinomaView official trial listing → -
Completed NCT NCT04109456
IN10018 Monotherapy and Combination Therapy for Metastatic Melanoma
Not yet reported InxMed (Shanghai) Co., Ltd. 51 participants Est. completion 2024-12-20 8 sites Stand-aloneOther conditions: Metastatic MelanomaView official trial listing → -
Status unknown NCT NCT04115410
PD-1 Immune Checkpoint Inhibitors and Immune-Related Adverse Events: a Cohort Study
Sungkyunkwan University 4724 participants Est. completion 2021-12-31Other conditions: Carcinoma, Non-Small-Cell Lung, Immune-Related Adverse EventsView official trial listing → -
Terminated NCT NCT04116320
Focused Ultrasound Ablation and PD-1 Antibody Blockade in Advanced Solid Tumors
Not yet reported Craig L Slingluff, Jr 5 participants Est. completion 2023-08-15 1 siteObstructive sleep apnea Other conditions: Melanoma, Breast Cancer, Merkel Cell Carcinoma, Squamous Cell Cancer, Non Small Cell Lung Cancer, Cervical Cancer, Urothelial Carcinoma, Ovarian Cancer, Hepatocellular Carcinoma, Small-cell Lung Cancer, Gastric Cancer, Esophageal CancerView official trial listing → -
Completed NCT NCT04123470
A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant Melanoma
Not yet reported, Not yet reported Lokon Pharma AB 24 participants Est. completion 2023-07-30 3 sites Stand-aloneOther conditions: Malignant MelanomaView official trial listing → -
Status unknown NCT NCT04134000
Atezolizumab and BCG in High Risk BCG naïve Non-muscle Invasive Bladder Cancer (NMIBC) Patients (BladderGATE)
Not yet reported Fundacion Oncosur 40 participants Est. completion 2024-09 1 site Stand-aloneOther conditions: Invasive Bladder CancerView official trial listing → -
Status unknown NCT NCT04135690
HAIC Plus Toripalimab vs. HAIC Plus Sorafenib for HCC With PVTT: a Non-comparative, Prospective, Randomized Trial
Not yet reported Sun Yat-sen University 60 participants Est. completion 2023-12-20 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT04136470
BioForte Technology for in Silico Identification of Candidates for a New Microbiome-based Therapeutics and Diagnostics
Ardigen 130 participants Est. completion 2021-03-31 10 sitesOther conditions: Non Small Cell Lung Cancer, Microbiome, Metagenome, Immunotherapy, MelanomaView official trial listing → -
Active, not recruiting NCT NCT04138628
Treatment Of Metastatic Bladder Cancer at the Time Of Biochemical reLApse Following Radical Cystectomy
Not yet reported Jørgen Bjerggaard Jensen 154 participants Est. completion 2030-11-01 5 sites Stand-aloneOther conditions: Bladder Cancer, Bladder Cancer, MetastaticView official trial listing → -
Status unknown NCT NCT04145232
AImmune - Artificial Intelligence Algorithm for Identification of Immunogenic Neoepitopes of Cancer to Predict and Boost Patient's Response to Immunotherapies.
Ardigen 30 participants Est. completion 2020-11-30 1 siteOther conditions: Non Small Cell Lung Cancer, Neoepitopes, Neoantigens, Immunotherapy, Next Generation Sequencing (NGS), Personalized Neoantigen Cancer VaccineView official trial listing → -
Completed NCT NCT04147351
A Phase II Study of Atezolizumab in Combination With Bevacizumab, Carboplatin or Cisplatin, and Pemetrexed for EGFR-mutant Metastatic Non-small Cell Lung Cancer Patients After Failure of EGFR Tyrosine Kinase Inhibitors.
Not yet reported National Taiwan University Hospital 22 participants Est. completion 2026-02-04 1 site Stand-aloneOther conditions: NSCLC Stage IIIB~IVView official trial listing → -
Completed NCT NCT04148911
A Study of Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative Breast Cancer
Not yet reported Hoffmann-La Roche 184 participants Est. completion 2024-12-15 67 sites Stand-aloneOther conditions: Triple-Negative Breast CancerView official trial listing → -
Completed NCT NCT04157985
Evaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid Tumors
Not yet reported Dan Zandberg 161 participants Est. completion 2025-11-07 1 siteOther conditions: Advanced Solid Tumors, NSCLC, Bladder Cancer, HNSCC, Renal Cancer, Melanoma, Anal Cancer, Colorectal Cancer, Cholangiocarcinoma, Gastric Cancer, Hepatocellular Carcinoma, Merkel Cell Carcinoma, Cervical CancerView official trial listing → -
Completed NCT NCT04158258
A Study to Describe the Diagnosis, Anti-Cancer Treatment and Clinical Outcome in Patients With Newly Diagnosed Breast Cancer in Latin America
Hoffmann-La Roche 2907 participants Est. completion 2026-07-31 30 sitesOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT04160494
D2C7-IT With Atezolizumab for Recurrent Gliomas
Not yet reported Darell Bigner 14 participants Est. completion 2026-06-11 1 site Stand-aloneOther conditions: Malignant GliomaView official trial listing → -
Active, not recruiting NCT NCT04161755
Study of Personalized Tumor Vaccines (PCVs) and a PD-L1 Blocker in Patients With Pancreatic Cancer That Can be Treated With Surgery
Not yet reported Memorial Sloan Kettering Cancer Center 29 participants Est. completion 2026-11-11 7 sites Stand-aloneOther conditions: Pancreatic CancerView official trial listing → -
Active, not recruiting NCT NCT04166721
WaKING: Wnt and checKpoint INhibition in Gastric Cancer
Not yet reported, Not yet reported Royal Marsden NHS Foundation Trust 52 participants Est. completion 2025-12-31 1 site Stand-aloneOther conditions: Metastatic Esophageal Cancer, Metastatic Gastric CancerView official trial listing → -
Terminated NCT NCT04167137
Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult Participants
Not yet reported Synlogic 32 participants Est. completion 2021-12-09 6 sites Stand-aloneOther conditions: Metastatic Solid Neoplasm, LymphomaView official trial listing → -
Status unknown NCT NCT04169867
Polish Microbiome Map
Ardigen 1160 participants Est. completion 2020-12-31 1 siteOther conditions: Melanoma, Healthy Volunteers, Microbiome, Metagenome, ImmunotherapyView official trial listing → -
Completed NCT NCT04170556
Regorafenib Followed by Nivolumab in Patients With Hepatocellular Carcinoma (GOING)
Not yet reported, Not yet reported Fundacion Clinic per a la Recerca Biomédica 69 participants Est. completion 2024-07-09 7 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT04177108
A Study of Ipatasertib in Combination With Atezolizumab and Paclitaxel as a Treatment for Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer
Not yet reported Hoffmann-La Roche 242 participants Est. completion 2023-02-28 182 sites Stand-aloneOther conditions: Triple-Negative Breast CancerView official trial listing → -
Active, not recruiting NCT NCT04180072
Atezolizumab Plus Bevacizumab With HCC and HBV Infection
Not yet reported National Health Research Institutes, Taiwan 51 participants Est. completion 2026-12-31 7 sites Stand-aloneOther conditions: Carcinoma, HepatocellularView official trial listing → -
Status unknown NCT NCT04185831
A MolEcularly Guided Anti-Cancer Drug Off-Label Trial
Not yet reported Uppsala University Hospital 167 participants Est. completion 2024-10 3 sites Stand-aloneOther conditions: Solid TumorView official trial listing → -
Active, not recruiting NCT NCT04185883
Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)
Not yet reported Amgen 610 participants Est. completion 2027-12-05 90 sites Stand-aloneOther conditions: Advanced Solid Tumors, Kirsten Rat Sarcoma (KRAS) pG12C MutationView official trial listing → -
Active, not recruiting NCT NCT04186013
Efficacy of Atezolizumab Concurrent With Radiotherapy in Patients With Muscle-invasive Bladder cáncer
Not yet reported Spanish Oncology Genito-Urinary Group 39 participants Est. completion 2027-05 10 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT04194203
A Study of Bevacizumab, Carboplatin, and Paclitaxel or Pemetrexed With or Without Atezolizumab in Chemotherapy-Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer (IMpower151)
Not yet reported Hoffmann-La Roche 305 participants Est. completion 2024-06-27 23 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Completed NCT NCT04196530
BDB001-102: Open Label Dose Escalation of BDB001 in Combination w Atezolizumab
Not yet reported Eikon Therapeutics 40 participants Est. completion 2024-08-15 5 sites Stand-aloneOther conditions: Tumor, SolidView official trial listing → -
Active, not recruiting NCT NCT04214262
Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer
Not yet reported National Cancer Institute (NCI) 417 participants Est. completion 2027-06-09 391 sites Stand-aloneOther conditions: Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8View official trial listing → -
Terminated NCT NCT04214418
Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies
Not yet reported, Not yet reported Columbia University 27 participants Est. completion 2022-07-01 2 sites Stand-aloneOther conditions: Gastrointestinal CancerView official trial listing → -
Completed NCT NCT04216953
MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma
Not yet reported, Not yet reported Centre Leon Berard 229 participants Est. completion 2025-03-17 6 sites Stand-aloneOther conditions: Sarcoma,Soft TissueView official trial listing → -
Terminated NCT NCT04220775
Bintrafusp Alfa and Stereotactic Body Radiation Therapy for the Treatment of Recurrent or Second Primary Head and Neck Squamous Cell Cancer
Not yet reported, Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2022-10-03 1 siteOther conditions: Recurrent Head and Neck Squamous Cell Carcinoma, Second Primary Squamous Cell Carcinoma of the Head and NeckView official trial listing → -
Completed NCT NCT04221529
Patients With ES-SCLC and ECOG PS=2 Receiving Atezolizumab-Carboplatin-Etoposide
Not yet reported AIO-Studien-gGmbH 70 participants Est. completion 2025-04-11 19 sites Stand-aloneOther conditions: SCLC, Extensive StageView official trial listing → -
Terminated NCT NCT04222426
89Zr-atezolizumab PET Scan and Lobular Breast Cancer
Not yet reported University Medical Center Groningen 1 participants Est. completion 2022-05-01 1 site Stand-aloneOther conditions: Lobular Metastatic Breast CancerView official trial listing → -
Status unknown NCT NCT04224636
Atezolizumab/Bevacizumab Followed by On-demand TACE or Initial Synchronous Treatment With TACE and Atezolizumab/Bevacizumab
Not yet reported Ludwig-Maximilians - University of Munich 106 participants Est. completion 2025-03-01 7 sites Stand-aloneOther conditions: Hepatocellular Carcinoma Non-resectableView official trial listing → -
Completed NCT NCT04245085
ABC-lung: Atezolizumab, Bevacizumab and Chemotherapy in EGFR-mutant Non-small Cell Lung Carcinoma
Not yet reported ETOP IBCSG Partners Foundation 95 participants Est. completion 2024-07-22 18 sitesOther conditions: EGFRmutant Stage IIIB/C or IV Non-squamous NSCLCView official trial listing → -
Withdrawn NCT NCT04249167
Cryoablation, Atezolizumab/Nab-paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer
Not yet reported Mayo Clinic Est. completion 2021-11-17 Stand-aloneOther conditions: Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8, Anatomic Stage IIIC Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Locally Advanced Breast Carcinoma, Metastatic Triple-Negative Breast Carcinoma, Prognostic Stage III Breast Cancer AJCC v8, Prognostic Stage IIIA Breast Cancer AJCC v8, Prognostic Stage IIIB Breast Cancer AJCC v8, Prognostic Stage IIIC Breast Cancer AJCC v8, Prognostic Stage IV Breast Cancer AJCC v8View official trial listing → -
Completed NCT NCT04250155
An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Genentech, Inc. 195 participants Est. completion 2026-05-27 25 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Status unknown NCT NCT04253145
Study to Assess Safety,Tolerability,Efficacy of PM01183 and Atezolizumab in Patients w/ Advanced Small Cell Lung Cancer.
Not yet reported, Not yet reported Fundacion Oncosur 184 participants Est. completion 2025-05 13 sites Stand-aloneOther conditions: Carcinoma, Small Cell LungView official trial listing → -
Completed NCT NCT04256421
A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 490 participants Est. completion 2025-07-31 121 sites Stand-aloneOther conditions: Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT04262154
Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate Cancer
Not yet reported Memorial Sloan Kettering Cancer Center 28 participants Est. completion 2026-09 8 sites Stand-aloneOther conditions: Metastatic Prostate CancerView official trial listing → -
Withdrawn NCT NCT04267237
A Study of the Efficacy and Safety of RO7198457 in Combination With Atezolizumab Versus Atezolizumab Alone Following Adjuvant Platinum-Doublet Chemotherapy in Participants Who Are ctDNA Positive After Surgical Resection of Stage II-III Non-Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche Est. completion 2025-09-30 Stand-aloneOther conditions: Non-small Cell Lung Cancer (NSCLC)View official trial listing → -
Status unknown NCT NCT04268368
Immune Related-adverse Events in Patients Receiving Immune Checkpoint Inhibitors
Università Politecnica delle Marche 200 participants Est. completion 2022-01-01 1 siteOther conditions: Cancer, Lung Cancer, Renal Cell Carcinoma, MelanomaView official trial listing → -
Withdrawn NCT NCT04272645
Abemaciclib With or Without Atezolizumab in Metastatic Castration Resistant Prostate Cancer
Not yet reported University of Michigan Rogel Cancer Center Est. completion 2022-10 4 sites Stand-aloneOther conditions: Prostate CancerView official trial listing → -
Terminated NCT NCT04274023
Study on TSR-042 in Advanced Clear Cell Sarcoma
Not yet reported Italian Sarcoma Group 3 participants Est. completion 2024-01-29 1 siteOther conditions: Sarcoma, Clear CellView official trial listing → -
Terminated NCT NCT04276376
Efficacy and Safety of the Combination of Rucaparib (PARP Inhibitor) and Atezolizumab (Anti-PD-L1 Antibody) in Patients With DNA Repair-deficient or Platinum-sensitive Solid Tumors
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 130 participants Est. completion 2023-12-12 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Active, not recruiting NCT NCT04289779
Study of CAbozantinib in Combination with AtezolizumaB for Muscle-Invasive BladdEr Cancer
Not yet reported Deepak Kilari 46 participants Est. completion 2025-12 6 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT04294810
A Study of Tiragolumab in Combination With Atezolizumab Compared With Placebo in Combination With Atezolizumab in Patients With Previously Untreated Locally Advanced Unresectable or Metastatic PD-L1-Selected Non-Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 620 participants Est. completion 2025-12-30 134 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT04300647
A Study of Tiragolumab Plus Atezolizumab and Atezolizumab Monotherapy in Participants With Metastatic and/or Recurrent PD-L1-Positive Cervical Cancer
Not yet reported Hoffmann-La Roche 172 participants Est. completion 2025-02-24 58 sites Stand-aloneOther conditions: Cervical CancerView official trial listing → -
Terminated NCT NCT04303858
A Study to Evaluate Safety and Anti-Tumor Activity of Eciskafusp Alfa (RO7284755) Alone or in Combination With Atezolizumab in Participants With Advanced and/or Metastatic Solid Tumors
Not yet reported Hoffmann-La Roche 189 participants Est. completion 2025-10-02 12 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Terminated NCT NCT04308785
A Study of Atezolizumab With or Without Tiragolumab Consolidation in Limited Stage Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 24 participants Est. completion 2023-07-25 17 sites Stand-aloneOther conditions: Carcinoma, Small Cell LungView official trial listing → -
Active, not recruiting NCT NCT04310020
Study of Radiation Therapy Followed by Atezolizumab in Stage II or III Non-small Cell Lung Cancer Patients
Not yet reported National Cancer Institute (NCI) 47 participants Est. completion 2027-06-01 170 sites Stand-aloneOther conditions: Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8View official trial listing → -
Completed NCT NCT04312308
A Study for Identification of Predictive Immune Biomarker for Atezolizumab Therapy in NSCLC Patients
Yonsei University 100 participants Est. completion 2025-01-26 1 siteOther conditions: Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT04321330
A Study to Investigate the Efficacy and Safety of Atezolizumab (Tecentriq) in Previously-Treated Patients With Advanced Thymic Carcinoma
Not yet reported Hoffmann-La Roche 34 participants Est. completion 2024-06-03 10 sites Stand-aloneOther conditions: Carcinoma, ThymicView official trial listing → -
Terminated NCT NCT04322643
Intermittent Checkpoint Inhibitor Therapy In Patients With Advanced Urothelial Carcinoma
Not yet reported Case Comprehensive Cancer Center 4 participants Est. completion 2023-04-17 1 site Stand-aloneOther conditions: Urothelial CarcinomaView official trial listing → -
Active, not recruiting NCT NCT04334941
Testing Maintenance Therapy for Small Cell Lung Cancer in Patients With SLFN11 Positive Biomarker
Not yet reported National Cancer Institute (NCI) 103 participants Est. completion 2027-01-21 561 sites Stand-aloneOther conditions: Extensive Stage Lung Small Cell CarcinomaView official trial listing → -
Terminated NCT NCT04338269
A Study of Atezolizumab in Combination With Cabozantinib Compared to Cabozantinib Alone in Participants With Advanced Renal Cell Carcinoma After Immune Checkpoint Inhibitor Treatment
Not yet reported Hoffmann-La Roche 522 participants Est. completion 2025-03-24 135 sites Stand-aloneOther conditions: Carcinoma, Renal CellView official trial listing → -
Status unknown NCT NCT04355806
Impact of Inactivated Trivalent Influenza Vaccine on NSCLC Patients Receiving PD-1 / PD-L1 Inhibitors
Shanghai Pulmonary Hospital, Shanghai, China 160 participants Est. completion 2023-05-31 2 sitesOther conditions: Non Small Cell Lung Cancer, Influenza VaccineView official trial listing → -
Active, not recruiting NCT NCT04356729
A Phase II Trial of PD-L1 Therapy Combined With Anti-VEGF Therapy in Unresectable or Metastatic Melanoma
Not yet reported F. Stephen Hodi, MD 30 participants Est. completion 2028-06-01 3 sites Stand-aloneOther conditions: Clinical Stage III Cutaneous Melanoma AJCC v8, Stage IV Melanoma, Unresectable Stage III Cutaneous Melanoma, Unresectable Stage IV Cutaneous MelanomaView official trial listing → -
Active, not recruiting NCT NCT04367311
Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA)
Not yet reported Nasser Hanna 100 participants Est. completion 2026-03 9 sites Stand-aloneOther conditions: Lung Cancer, NSCLCView official trial listing → -
Terminated NCT NCT04373369
Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer
Not yet reported Washington University School of Medicine 11 participants Est. completion 2025-08-11 1 site Stand-aloneOther conditions: Extensive-stage Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT04387084
Short-term Fasting Prior to PD-1/PD-L1 Inhibitor Therapy for of Advanced or Metastatic Skin Malignancy
Not yet reported University of Southern California 10 participants Est. completion 2028-03-31 2 sites Stand-aloneOther conditions: Advanced Malignant Skin Neoplasm, Metastatic Malignant Skin NeoplasmView official trial listing → -
Terminated NCT NCT04396535
Docetaxel With or Without Bintrafusp Alfa for the Treatment of Advanced Non-small Cell Lung Cancer
Not yet reported Mayo Clinic 10 participants Est. completion 2023-12-31 3 sitesOther conditions: Advanced Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8View official trial listing → -
Completed NCT NCT04400474
Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Study
Not yet reported Grupo Espanol de Tumores Neuroendocrinos 93 participants Est. completion 2023-12-15 15 sites Stand-aloneOther conditions: Neuroendocrine Tumor, Anaplastic Thyroid Cancer, Adenocarcinoma, Pheochromocytoma, ParagangliomaView official trial listing → -
Suspended NCT NCT04402788
Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial
Not yet reported, Not yet reported National Cancer Institute (NCI) 138 participants Est. completion 2027-04-30 411 sites Stand-aloneOther conditions: Extensive Stage Lung Small Cell CarcinomaView official trial listing → -
Terminated NCT NCT04404140
A Study Evaluating The Safety, Efficacy and Pharmacokinetics Of Ipatasertib In Combination With Atezolizumab And Docetaxel In Metastatic Castration-Resistant Prostate Cancer (mCRPC).
Not yet reported Hoffmann-La Roche 6 participants Est. completion 2022-10-14 9 sites Stand-aloneOther conditions: Castration-Resistant Prostatic CancerView official trial listing → -
Completed NCT NCT04405349
Investigating the Combination of VB10.16 and Atezolizumab in Patients With HPV 16-positive Cervical Cancer
Not yet reported Nykode Therapeutics ASA 52 participants Est. completion 2023-11-24 21 sites Stand-aloneOther conditions: Cervical Cancer, Cervix CancerView official trial listing → -
Completed NCT NCT04408118
First Line Atezolizumab, Paclitaxel, and Bevacizumab (Avastin®) in mTNBC
Not yet reported MedSIR 100 participants Est. completion 2023-12-07 26 sites Stand-aloneOther conditions: Metastatic Breast Cancer, Advanced Breast Cancer, Triple Negative Breast CancerView official trial listing → -
Terminated NCT NCT04422210
A Study Evaluating The Safety, Tolerability, Pharmacokinetics, And Efficacy Of Venetoclax In Combination With Atezolizumab, Carboplatin, And Etoposide In Participants With Untreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC).
Not yet reported Hoffmann-La Roche 2 participants Est. completion 2020-11-06 5 sites Stand-aloneOther conditions: Small Cell Lung CancerView official trial listing → -
Completed NCT NCT04426825
A Study of Atezolizumab in Combination With Bevacizumab in Patients With EGFR Mutation Positive Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 23 participants Est. completion 2023-02-10 10 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Terminated NCT NCT04432207
A Study of IMU-201 (PD1-Vaxx), a B-Cell Immunotherapy, in Adults With Non-Small Cell Lung Cancer
Not yet reported Imugene Limited 24 participants Est. completion 2024-11-07 6 sites Stand-aloneOther conditions: Non Small Cell Lung Cancer, Non Small Cell Lung Cancer Stage IIIB, Non-small Cell Lung Cancer Stage IV, Squamous Non-small-cell Lung Cancer, Large Cell Carcinoma Lung, Adenocarcinoma LungView official trial listing → -
Completed NCT NCT04432597
HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated Cancers
Not yet reported, Not yet reported National Cancer Institute (NCI) 39 participants Est. completion 2026-03-31 1 siteOther conditions: HPV Positive Cancer, Vulvar, Vaginal, Penile, Rectal Cancer, Anal Cancer, Oropharyngeal Cancer, Cervical CancerView official trial listing → -
Active, not recruiting NCT NCT04440735
A Study of DSP107 Alone and in Combination with Atezolizumab for Patients with Advanced Solid Tumors
Not yet reported, Not yet reported Kahr Medical 125 participants Est. completion 2025-09 7 sites Stand-aloneOther conditions: Advanced Solid Tumor, Non Small Cell Lung Cancer, Colorectal CancerView official trial listing → -
Terminated NCT NCT04442126
A Study of NM21-1480 in Adult Patients With Advanced Solid Tumors
Not yet reported, Not yet reported Numab Therapeutics AG 52 participants Est. completion 2024-02-06 26 sitesOther conditions: Advanced Solid Tumor, Non-small Cell Lung Cancer, Colorectal Cancer, Squamous Cell Carcinoma, Ovarian Carcinoma, Peritoneal Carcinoma, Fallopian Tube Cancer, Head and Neck Squamous Cell Carcinoma, Triple Negative Breast CancerView official trial listing → -
Active, not recruiting NCT NCT04446117
Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC
Not yet reported Exelixis 575 participants Est. completion 2026-10-16 280 sites Stand-aloneOther conditions: Metastatic Prostate Cancer, Prostate AdenocarcinomaView official trial listing → -
Active, not recruiting NCT NCT04449874
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation
Not yet reported Genentech, Inc. 498 participants Est. completion 2027-12-31 63 sites Stand-aloneOther conditions: Non-Small Cell Lung Cancer, Colorectal Cancer, Advanced Solid TumorsView official trial listing → -
Completed NCT NCT04457778
First in Human Study of M6223
Not yet reported EMD Serono Research & Development Institute, Inc. 58 participants Est. completion 2023-06-23 4 sitesOther conditions: Metastatic Solid TumorsView official trial listing → -
Active, not recruiting NCT NCT04458922
Testing Atezolizumab in People 2-17 Years Old With Clear Cell Sarcoma or Advanced Chondrosarcoma
Not yet reported National Cancer Institute (NCI) 27 participants Est. completion 2026-12-17 15 sites Stand-aloneObstructive sleep apnea Other conditions: Metastatic Clear Cell Sarcoma of Soft TissueView official trial listing → -
Completed NCT NCT04462276
Thoracic RadiothErapy With Atezolizumab in Small Cell lUng canceR Extensive Disease
Not yet reported Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 68 participants Est. completion 2024-09-02 20 sites Stand-aloneOther conditions: Small Cell Lung Cancer Extensive Stage, Thoracic RadiotherapyView official trial listing → -
Status unknown NCT NCT04465942
Immunotherapy in Lung Cancer: Treatment After IO Cessation.
European Lung Cancer Working Party 300 participants Est. completion 2025-06 5 sitesOther conditions: Carcinoma, Non-Small-Cell Lung, ImmunotherapyView official trial listing → -
Terminated NCT NCT04471415
Study to Investigate DRP-104 in Adults With Advanced Solid Tumors
Not yet reported, Not yet reported Dracen Pharmaceuticals, Inc. 61 participants Est. completion 2023-03-28 22 sites Stand-aloneOther conditions: Advanced Solid Tumor, Non Small Cell Lung Cancer MetastaticView official trial listing → -
Completed NCT NCT04471428
Study of Atezolizumab in Combination With Cabozantinib Versus Docetaxel in Patients With Metastatic Non-Small Cell Lung Cancer Previously Treated With an Anti-PD-L1/PD-1 Antibody and Platinum-Containing Chemotherapy
Not yet reported Hoffmann-La Roche 366 participants Est. completion 2025-01-17 92 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell LungView official trial listing → -
Active, not recruiting NCT NCT04471727
A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001)
Not yet reported, Not yet reported Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 232 participants Est. completion 2028-01-28 11 sites Stand-aloneOther conditions: Small-Cell Lung Cancer, Neuroendocrine CarcinomaView official trial listing → -
Completed NCT NCT04477759
Dose-Escalated Hypofractionated Adaptive Radiotherapy for Head and Neck Cancer
Not yet reported Medical College of Wisconsin 18 participants Est. completion 2025-04-14 1 site Stand-aloneOther conditions: Head and Neck NeoplasmView official trial listing → -
Completed NCT NCT04480372
SAKK 17/18 (ORIGIN) MPM & NSCLC >1st Line Gemci & Atezo Ph II
Not yet reported Swiss Cancer Institute 68 participants Est. completion 2024-04-03 12 sites Stand-aloneOther conditions: Malignant Pleural Mesothelioma, Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT04487067
A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista
Not yet reported Hoffmann-La Roche 152 participants Est. completion 2024-08-13 21 sites Stand-aloneOther conditions: Carcinoma, HepatocellularView official trial listing → -
Completed NCT NCT04487756
Combination of Atezolizumab With Dendritic Cell Vaccine in Patients With Lung Cancer
Not yet reported, Not yet reported Instituto Oncológico Dr Rosell 20 participants Est. completion 2025-09-08 3 sites Stand-aloneOther conditions: Extensive-stage Small Cell Lung CancerView official trial listing → -
Completed NCT NCT04501497
Prospective Multicenter Observational Study of Atezolizumab Combination Therapy in Lung Cancer (J-TAIL-2)
Chugai Pharmaceutical 1221 participants Est. completion 2023-02-03 148 sitesOther conditions: Non-small Cell Lung Cancer, Extensive Disease Small Cell Lung CancerView official trial listing → -
Completed NCT NCT04504669
First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours
Not yet reported AstraZeneca 60 participants Est. completion 2024-10-07 13 sitesOther conditions: Clear Cell Renal Cell Cancer, Non-Small-Cell Lung Cancer, Triple Negative Breast Neoplasms, Squamous Cell Cancer of Head and Neck, Small Cell Lung Cancer, Gastroesophageal Cancer, Melanoma, Cervical Cancer, Advanced Solid TumoursView official trial listing → -
Withdrawn NCT NCT04510584
Maintenance Treatment With Bevacizumab and Atezolizumab for Ovarian Cancer
Not yet reported University Health Network, Toronto Est. completion 2023-02-22 1 site Stand-aloneOther conditions: Ovarian Endometrioid Tumor, Fallopian Tube Cancer, Primary Peritoneal Cancer, TP53 MutationView official trial listing → -
Terminated NCT NCT04512430
Neo-DIANA: Neoadjuvant Treatment for EGFR Mutated Patients
Not yet reported Fundación GECP 4 participants Est. completion 2024-07-19 18 sites Stand-aloneOther conditions: Non Small Cell Lung Cancer, EGFR Gene MutationView official trial listing → -
Completed NCT NCT04513925
A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)
Not yet reported Hoffmann-La Roche 829 participants Est. completion 2025-07-31 189 sites Stand-aloneOther conditions: Non-small Cell Lung Cancer (NSCLC)View official trial listing → -
Active, not recruiting NCT NCT04524871
A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)
Not yet reported, Not yet reported Hoffmann-La Roche 518 participants Est. completion 2027-09-30 32 sites Stand-aloneOther conditions: Advanced Liver CancersView official trial listing → -
Completed NCT NCT04540211
A Study of Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal Carcinoma
Not yet reported Hoffmann-La Roche 461 participants Est. completion 2025-08-28 67 sites Stand-aloneOther conditions: Esophageal CancerView official trial listing → -
Terminated NCT NCT04541173
Study of Atezolizumab and Bevacizumab With Y-90 TARE in Patients With Unresectable Hepatocellular Carcinoma (HCC)
Not yet reported Aiwu Ruth He, MD 6 participants Est. completion 2023-06-30 6 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT04543617
A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy
Not yet reported Hoffmann-La Roche 760 participants Est. completion 2026-07-22 166 sites Stand-aloneOther conditions: Esophageal Squamous Cell CarcinomaView official trial listing → -
Terminated NCT NCT04549428
Atezolizumab Plus 8 Gy Single-fraction Radiotherapy for Advanced Oligoprogressive NSCLC
Not yet reported Oncology Institute of Southern Switzerland 12 participants Est. completion 2025-05-31 3 sites Stand-aloneOther conditions: NSCLC Stage IVView official trial listing → -
Completed NCT NCT04551521
CRAFT: The NCT-PMO-1602 Phase II Trial
Not yet reported German Cancer Research Center 72 participants Est. completion 2024-12-30 9 sites Stand-aloneOther conditions: Metastatic or Locally Advanced MalignanciesView official trial listing → -
Terminated NCT NCT04560686
Bintrafusp Alfa Before Surgery for the Treatment of Untreated Resectable Non-small Cell Lung Cancer
Not yet reported M.D. Anderson Cancer Center 2 participants Est. completion 2021-07-01 1 siteOther conditions: Resectable Lung Non-Small Cell Carcinoma, Stage I Lung Cancer AJCC v8, Stage IA1 Lung Cancer AJCC v8, Stage IA2 Lung Cancer AJCC v8, Stage IA3 Lung Cancer AJCC v8, Stage IB Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8View official trial listing → -
Active, not recruiting NCT NCT04560972
LB-100, Carboplatin, Etoposide, and Atezolizumab for the Treatment of Untreated Extensive-Stage Small Cell Lung Cancer
Not yet reported City of Hope Medical Center 3 participants Est. completion 2027-01-27 1 site Stand-aloneOther conditions: Extensive Stage Lung Small Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT04563338
An Exploratory Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma and Non-Small Cell Lung Cancer With Liver Metastases (INTEGRATE)
Not yet reported University Health Network, Toronto 36 participants Est. completion 2026-08-31 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma, Non-small Cell Lung Cancer Metastatic, Liver MetastasesView official trial listing → -
Status unknown NCT NCT04564482
PD-L1 PET Imaging During Neoadjuvant (Chemo)Radiotherapy in Esophageal and Rectal Cancer
Not yet reported Johannes Laengle, MD, PhD 20 participants Est. completion 2026-06-01 1 siteOther conditions: Rectal Cancer Stage, Oesophageal CancerView official trial listing → -
Completed NCT NCT04584112
A Study of the Safety, Efficacy, and Pharmacokinetics of Tiragolumab in Combination With Atezolizumab and Chemotherapy in Participants With Triple-Negative Breast Cancer
Not yet reported Hoffmann-La Roche 83 participants Est. completion 2023-03-08 24 sites Stand-aloneOther conditions: Triple-Negative Breast CancerView official trial listing → -
Active, not recruiting NCT NCT04589845
Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study
Not yet reported Hoffmann-La Roche 920 participants Est. completion 2032-09-25 112 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Status unknown NCT NCT04591431
The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy
Not yet reported Fondazione per la Medicina Personalizzata 400 participants Est. completion 2025-06 37 sites Stand-aloneOther conditions: Breast Cancer, Gastrointestinal Cancer, Non Small Cell Lung Cancer, Other CancerView official trial listing → -
Completed NCT NCT04602078
Study of Atezolizumab Combined With Split-dose Gemcitabine Plus Cisplatin in Urothelial Carcinoma
Not yet reported Spanish Oncology Genito-Urinary Group 82 participants Est. completion 2024-02-02 12 sites Stand-aloneOther conditions: Locally Advanced or Metastatic Urothelial CarcinomaView official trial listing → -
Terminated NCT NCT04604132
Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric Adenocarcinoma
Not yet reported, Not yet reported Basilea Pharmaceutica 47 participants Est. completion 2022-11-21 81 sitesOther conditions: Gastric AdenocarcinomaView official trial listing → -
Terminated NCT NCT04610684
Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases
Not yet reported Jeffrey Clarke 3 participants Est. completion 2022-09-20 6 sites Stand-aloneOther conditions: Small-cell Lung Cancer, Brain MetastasesView official trial listing → -
Withdrawn NCT NCT04611776
A Study Evaluating the Efficacy and Safety of Adjuvant Platinum-Doublet Chemotherapy, With or Without Atezolizumab, in Patients Who Are ctDNA Positive After Complete Surgical Resection of Stage IB to Select IIIB Non-Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche Est. completion 2026-01-08 Stand-aloneOther conditions: Carcinoma, Non-Small Cell LungView official trial listing → -
Completed NCT NCT04619797
A Study of Tiragolumab in Combination With Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin Versus Pembrolizumab Plus Pemetrexed and Carboplatin/Cisplatin in Participants With Previously Untreated Advanced Non-Squamous Non-Small Cell Lung Cancer
Not yet reported, Not yet reported Hoffmann-La Roche 542 participants Est. completion 2025-11-20 127 sites Stand-aloneOther conditions: Non-small Cell Lung Cancer (NSCLC)View official trial listing → -
Completed NCT NCT04622228
Study of Low-Dose Radiotherapy (LDRT) Concurrent Cisplatin/Carboplatin Plus Etoposide With Atezolizumab for Patients With Extensive-Stage Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 56 participants Est. completion 2024-06-30 8 sites Stand-aloneOther conditions: Carcinoma, Small Cell LungView official trial listing → -
Completed NCT NCT04624399
Neoadjuvant Immune Checkpoint Inhibitor Treatment in Urothelial Cancer
Not yet reported Queen Mary University of London 32 participants Est. completion 2026-05-30 1 site Stand-aloneOther conditions: Urogenital CancerView official trial listing → -
Withdrawn NCT NCT04630210
Investigating Atezolizumab in Newly Diagnosed ER Positive Breast Cancer Patients According to Their AdipOsity
Not yet reported Universitaire Ziekenhuizen KU Leuven Est. completion 2025-01-31 Stand-aloneOther conditions: Breast CancerView official trial listing → -
Active, not recruiting NCT NCT04630730
Intravesical Recombinant BCG Followed by Perioperative Chemo-immunotherapy for Patients With MIBC
Not yet reported Swiss Cancer Institute 46 participants Est. completion 2030-06 10 sites Stand-aloneOther conditions: Bladder CancerView official trial listing → -
Completed NCT NCT04631029
Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread
Not yet reported National Cancer Institute (NCI) 3 participants Est. completion 2023-07-11 5 sites Stand-aloneOther conditions: Extensive Stage Lung Small Cell Carcinoma, Malignant Solid Neoplasm, Metastatic Malignant Neoplasm in the BrainView official trial listing → -
Status unknown NCT NCT04631731
Risk Factors of Immune-ChEckpoint Inhibitors MEdiated Liver, Gastrointestinal, Endocrine and Skin Toxicity
Not yet reported, Not yet reported Western Sydney Local Health District 200 participants Est. completion 2025-12-10 2 sitesOther conditions: Lung Cancer, Nonsmall Cell, Renal Cell Carcinoma, Melanoma, Gastric Cancer, Hepatocellular Carcinoma, Endometrial Cancer, MesotheliomaView official trial listing → -
Completed NCT NCT04632992
A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response
Not yet reported Genentech, Inc. 252 participants Est. completion 2024-02-27 38 sites Stand-aloneOther conditions: Advanced Unresectable or Metastatic Solid MalignancyView official trial listing → -
Completed NCT NCT04636762
A Study of Concurrent Chemoradiation With Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)
Not yet reported Second Xiangya Hospital of Central South University 40 participants Est. completion 2022-05-01 2 sites Stand-aloneOther conditions: Extensive-stage Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT04637594
Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy
Not yet reported Alliance for Clinical Trials in Oncology 3 participants Est. completion 2030-09 377 sites Stand-aloneOther conditions: Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis Urothelial Carcinoma, Locally Advanced Ureter Urothelial Carcinoma, Locally Advanced Urethral Urothelial Carcinoma, Locally Advanced Urothelial Carcinoma, Metastatic Bladder Urothelial Carcinoma, Metastatic Renal Pelvis Urothelial Carcinoma, Metastatic Ureter Urothelial Carcinoma, Metastatic Urethral Urothelial Carcinoma, Metastatic Urothelial CarcinomaView official trial listing → -
Terminated NCT NCT04639245
Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer
Not yet reported, Not yet reported Fred Hutchinson Cancer Center 1 participants Est. completion 2022-08-16 1 site Stand-aloneOther conditions: Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Solid Neoplasm, Metastatic Triple-Negative Breast Carcinoma, Metastatic Urothelial Carcinoma, Stage IV Lung Cancer AJCC v8View official trial listing → -
Status unknown NCT NCT04639284
Anti-angiogenic Agents Plus Anti-PD-1 Antibodies for uHCC
Shanghai Zhongshan Hospital 200 participants Est. completion 2023-07-31 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT04642365
A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors.
Not yet reported Hoffmann-La Roche 49 participants Est. completion 2024-01-04 10 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Active, not recruiting NCT NCT04649489
A Study to Evaluate Efficacy and Safety of Hepatic Resection for Liver Cancer With PVTT, HVTT or IVCTT After Initial Ate/Bev
Not yet reported Jia Fan 501 participants Est. completion 2028-03-31 23 sites Stand-aloneOther conditions: Venous ThrombosisView official trial listing → -
Status unknown NCT NCT04659382
Study to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer
Not yet reported Federation Francophone de Cancerologie Digestive 52 participants Est. completion 2024-10-31 19 sites Stand-aloneOther conditions: Metastatic Colorectal Cancer, pMMR, MSS, Immune Checkpoint Inhibitor, Internal RadiotherapyView official trial listing → -
Active, not recruiting NCT NCT04660344
A Study of Atezolizumab Versus Placebo as Adjuvant Therapy in Participants With High-risk Muscle-invasive Bladder Cancer (MIBC) Who Are ctDNA Positive Following Cystectomy
Not yet reported Hoffmann-La Roche 761 participants Est. completion 2026-10-01 141 sites Stand-aloneOther conditions: Muscle-invasive Bladder CancerView official trial listing → -
Completed NCT NCT04661150
A Study of Atezolizumab and Trastuzumab in Combination With Capecitabine and Oxaliplatin in Patients With HER2 Positive Locally Advanced Resectable Gastric Cancer of Adenocarcinoma of Gastroesophageal Junction
Not yet reported Hoffmann-La Roche 42 participants Est. completion 2026-07-27 8 sites Stand-aloneOther conditions: Gastric Cancer, Gastroesophageal Junction AdenocarcinomaView official trial listing → -
Status unknown NCT NCT04663438
Real World Study of Efficacy and Safety of Atezolizumab Plus Chemotherapy in Chinese Patients With ES-SCLC
Peking Union Medical College Hospital 300 participants Est. completion 2021-05-30 1 siteOther conditions: Extensive-stage Small Cell Lung CancerView official trial listing → -
Completed NCT NCT04665843
A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck
Not yet reported Hoffmann-La Roche 123 participants Est. completion 2025-08-27 47 sites Stand-aloneOther conditions: Squamous Cell Carcinoma of Head and NeckView official trial listing → -
Completed NCT NCT04665856
Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 123 participants Est. completion 2025-11-17 16 sites Stand-aloneOther conditions: Small Cell Lung CarcinomaView official trial listing → -
Completed NCT NCT04670107
The Combination of Anlotinib and Immune Checkpoint Inhibitors for Advanced NSCLC Patients With Muti-line Therapy
Not yet reported, Not yet reported The Affiliated Hospital of Qingdao University 30 participants Est. completion 2020-11-01 1 siteOther conditions: NSCLC, Angiogenesis, ImmunotherapyView official trial listing → -
Completed NCT NCT04677504
A Study of Atezolizumab With or Without Bevacizumab in Combination With Cisplatin Plus Gemcitabine in Patients With Untreated, Advanced Biliary Tract Cancer
Not yet reported Hoffmann-La Roche 162 participants Est. completion 2023-08-25 49 sites Stand-aloneOther conditions: Biliary Tract CancerView official trial listing → -
Status unknown NCT NCT04680598
Comparison of HBV Reactivation Between Patients With High HBV-DNA and Low HBV-DNA Loads Undergoing ICI and Concurrent Antiviral Prophylaxis: a Prospective Observational Study
Sun Yat-sen University 800 participants Est. completion 2023-12-31 4 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT04690686
Immunopheresis Alone or in Combination With Paclitaxel or Atezolizumab in Non-small Cell Lung Cancer (NSCLC).
Not yet reported Immunicom Inc 24 participants Est. completion 2022-12-31 3 sites Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT04690855
A Study to Evaluate TAlazoparib, Radiotherapy and Atezolizumab in gBRCA 1/2 Negative Patients With PD-L1+ Metastatic Triple Negative Breast Cancer
Not yet reported Mylin A. Torres, MD 1 participants Est. completion 2022-12-20 2 sites Stand-aloneOther conditions: Breast Cancer, Triple Negative Breast CancerView official trial listing → -
Status unknown NCT NCT04696939
Combined Atezolizumab and Chemotherapy (Carboplatin Plus Etoposide) in Neoadjuvant Treating Limited-Stage Small Cell Lung Cancer Patients
Not yet reported Shanghai Pulmonary Hospital, Shanghai, China 100 participants Est. completion 2023-10 1 site Stand-aloneOther conditions: Small-cell Lung Cancer, Neoadjuvant TherapyView official trial listing → -
Active, not recruiting NCT NCT04708067
Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma
Not yet reported M.D. Anderson Cancer Center 2 participants Est. completion 2027-02-02 1 siteOther conditions: Locally Advanced Intrahepatic Cholangiocarcinoma, Metastatic Intrahepatic Cholangiocarcinoma, Stage III Intrahepatic Cholangiocarcinoma AJCC v8, Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8, Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8, Stage IV Intrahepatic Cholangiocarcinoma AJCC v8View official trial listing → -
Completed NCT NCT04710498
Neoadjuvant Atezolizumab in Surgically Resectable Advanced Cutaneous Squamous Cell Carcinoma
Not yet reported Stanford University 20 participants Est. completion 2024-02-15 1 site Stand-aloneOther conditions: Cutaneous Squamous Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT04712643
A Study of TACE Combined With Atezolizumab Plus Bevacizumab or TACE Alone in Patients With Untreated Heaptocellular Carcionma
Not yet reported Hoffmann-La Roche 342 participants Est. completion 2029-02-01 40 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT04713891
A Study of KF-0210 in Advanced Solid Tumors Patients
Not yet reported Keythera Pharmaceuticals (Australia) Pty Ltd 14 participants Est. completion 2023-04-27 1 site Stand-aloneOther conditions: Advanced Solid Tumor, Colorectal Cancer, Lung Cancer, Squamous Cell Carcinoma of the Esophagus, Gastric Cancer, Bladder CancerView official trial listing → -
Active, not recruiting NCT NCT04721132
Atezolizumab and Bevacizumab Before Surgery for the Treatment of Resectable Liver Cancer
Not yet reported M.D. Anderson Cancer Center 16 participants Est. completion 2027-12-31 2 sites Stand-aloneOther conditions: Resectable Hepatocellular Carcinoma, Stage I Hepatocellular Carcinoma AJCC v8, Stage IA Hepatocellular Carcinoma AJCC v8, Stage IB Hepatocellular Carcinoma AJCC v8, Stage II Hepatocellular Carcinoma AJCC v8View official trial listing → -
Active, not recruiting NCT NCT04722575
Combination or Sequence of Vemurafenib, Cobimetinib, and Atezolizumab in High-risk, Resectable Melanoma
Not yet reported Fondazione Melanoma Onlus 95 participants Est. completion 2027-06 6 sites Stand-aloneOther conditions: MelanomaView official trial listing → -
Active, not recruiting NCT NCT04727307
Neoadjuvant Atezo, Adjuvant Atezo + Beva Combined With RF Ablation of Small HCC: a Multicenter Randomized Phase II Trial
Not yet reported University Hospital, Montpellier 202 participants Est. completion 2031-02 19 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT04729959
Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma
Not yet reported National Cancer Institute (NCI) 61 participants Est. completion 2027-08-20 110 sites Stand-aloneOther conditions: Diffuse Astrocytoma, IDH-Wildtype, Recurrent GlioblastomaView official trial listing → -
Status unknown NCT NCT04730388
ATEZOLIZUMAB - BEVACIZUMAB in the Treatment Hepatocellular Carcinoma Inoperable or
University Hospital, Brest 100 participants Est. completion 2022-01-18Other conditions: Advanced Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT04730999
Efficacy and Safety Study of a New Therapeutic Strategy in the Treatment of Extended-Disease Small-Cell Lung Cancer
Not yet reported Gruppo Oncologico Italiano di Ricerca Clinica 54 participants Est. completion 2024-06-19 14 sites Stand-aloneOther conditions: Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT04732286
A Study of Atezolizumab in Combination With Bevacizumab in Spanish Patients With Unresectable or Unsuitable for Locoregional Treatments Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy
Not yet reported Hoffmann-La Roche 100 participants Est. completion 2024-04-26 25 sites Stand-aloneOther conditions: Carcinoma, HepatocellularView official trial listing → -
Completed NCT NCT04732598
A Phase III Study of Bevacizumab and Paclitaxel in Combination With Atezolizumab as a Treatment for Locally Advanced Unresectable or Metastatic Hormone Receptor-positive HER2 Negative Breast Cancer
Not yet reported Japanese Foundation for Cancer Research 281 participants Est. completion 2026-03-13 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT04739202
Personalized Targeted IMMUNOtherapy-based Regimens in Recurrent GASTric Adenocarcinoma (IMMUNOGAST)
Not yet reported Hospices Civils de Lyon 54 participants Est. completion 2026-06-04 8 sites Stand-aloneOther conditions: Gastric Adenocarcinoma, Metastatic Gastric Cancer, Metastatic Adenocarcinoma, Advanced Gastric CarcinomaView official trial listing → -
Status unknown NCT NCT04739670
Evaluating the Efficacy and Safety of Bevacizumab, Carboplatin, Gemcitabine and Atezolizumab in Breast Cancer
Not yet reported Peter MacCallum Cancer Centre, Australia 31 participants Est. completion 2025-09-30 4 sites Stand-aloneOther conditions: Metastatic Triple Negative Breast CancerView official trial listing → -
Terminated NCT NCT04740918
A Study of Trastuzumab Emtansine in Combination With Atezolizumab or Placebo as a Treatment for Participants With Human Epidermal Growth Factor 2 (HER2)-Positive and Programmed Death-ligand 1 (PD-L1)-Positive Locally Advanced (LABC) or Metastatic Breast Cancer (MBC)
Not yet reported Hoffmann-La Roche 96 participants Est. completion 2024-06-19 51 sites Stand-aloneOther conditions: Metastatic Breast CancerView official trial listing → -
Completed NCT NCT04751929
Abemaciclib With or Without Atezolizumab for mCRPC
Not yet reported Dana-Farber Cancer Institute 19 participants Est. completion 2025-11-06 1 site Stand-aloneOther conditions: Prostate Cancer, Metastatic Castration-resistant Prostate CancerView official trial listing → -
Withdrawn NCT NCT04756505
Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial
Not yet reported M.D. Anderson Cancer Center Est. completion 2022-02-16Other conditions: Anatomic Stage IV Breast Cancer AJCC v8, Hormone Receptor Positive Breast Adenocarcinoma, Metastatic Breast Carcinoma, Metastatic HER2 Negative Breast Adenocarcinoma, Prognostic Stage IV Breast Cancer AJCC v8View official trial listing → -
Active, not recruiting NCT NCT04759248
Study With Atezolizumab in Combination With Trastuzumab and Vinorelbine in HER2-positive Advanced/Metastatic Breast Cancer
Not yet reported SOLTI Breast Cancer Research Group 55 participants Est. completion 2027-07-01 15 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Terminated NCT NCT04770272
Study to Compare a Mono Atezolizumab Window Followed by a Atezolizumab - CTX Therapy With Atezolizumab - CTX Therapy
Not yet reported Palleos Healthcare GmbH 442 participants Est. completion 2024-10-02 1 site Stand-aloneOther conditions: Triple-negative Breast CancerView official trial listing → -
Active, not recruiting NCT NCT04770896
A Study of Atezolizumab With Lenvatinib or Sorafenib Versus Lenvatinib or Sorafenib Alone in Hepatocellular Carcinoma Previously Treated With Atezolizumab and Bevacizumab
Not yet reported Hoffmann-La Roche 557 participants Est. completion 2026-10-14 124 sites Stand-aloneOther conditions: Unresectable Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT04776447
Atezolizumab Plus Induction Chemotherapy Plus CT-radiotherapy. (APOLO)
Not yet reported Fundación GECP 38 participants Est. completion 2025-07-31 22 sites Stand-aloneOther conditions: Lung Diseases, Carcinoma, Non-Small-Cell Lung, Stage IIIA Non-small Cell Lung Cancer, Stage IIIB Non-small Cell Lung Cancer, Respiratory Tract Neoplasms, Carcinoma Bronchiogenic Stage III, Thoracic NeoplasmsView official trial listing → -
Terminated NCT NCT04789668
Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases
Not yet reported, Not yet reported M.D. Anderson Cancer Center 8 participants Est. completion 2023-12-08 1 siteOther conditions: Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Hematopoietic and Lymphoid Cell Neoplasm, Hormone Receptor Positive Breast Adenocarcinoma, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Solid Neoplasm, Metastatic Melanoma, Metastatic Triple-Negative Breast Carcinoma, Pathologic Stage IV Cutaneous Melanoma AJCC v8, Prognostic Stage IV Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8View official trial listing → -
Terminated NCT NCT04793399
Safety and Efficacy Evaluation of Bosutinib Plus Atezolizumab in Newly Diagnosed Chronic Leukemia Adult Patients
Not yet reported, Not yet reported Fundacion Espanola para la Curacion de la Leucemia Mieloide Cronica 9 participants Est. completion 2021-09-24 2 sites Stand-aloneOther conditions: Chronic Phase-Chronic Myeloid LeukemiaView official trial listing → -
Terminated NCT NCT04801966
Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study
Not yet reported Peter MacCallum Cancer Centre, Australia 3 participants Est. completion 2022-12-30 1 site Stand-aloneOther conditions: CancerView official trial listing → -
Active, not recruiting NCT NCT04808245
A MultIceNTER Phase I Peptide VaCcine Trial for the Treatment of H3-Mutated Gliomas
Not yet reported German Cancer Research Center 15 participants Est. completion 2026-11 8 sites Stand-aloneOther conditions: Newly Diagnosed H3-mutated GliomaView official trial listing → -
Completed NCT NCT04818983
The Biomarker Exploratory Study in Prospective Multicenter Observational Study of Atezolizumab Combination Therapy in Lung Cancer (J-TAIL-2)
Chugai Pharmaceutical 470 participants Est. completion 2023-02-03 95 sitesOther conditions: Non-small Cell Lung Cancer, Extensive Disease Small Cell Lung CancerView official trial listing → -
Completed NCT NCT04820179
Atezolizumab + Cabozantinib in Patients w/ Metastatic, Refractory Pancreatic Cancer
Not yet reported University of Arizona 32 participants Est. completion 2026-09-20 1 site Stand-aloneOther conditions: Pancreatic Cancer, Metastatic Pancreatic CancerView official trial listing → -
Completed NCT NCT04829383
A Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma
Not yet reported Howard S Hochster 6 participants Est. completion 2024-10-15 7 sites Stand-aloneOther conditions: Unresectable Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT04832854
A Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab, With or Without Platinum-Based Chemotherapy, in Participants With Previously Untreated Locally Advanced Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 50 participants Est. completion 2025-03-05 21 sites Stand-aloneOther conditions: Non-Small Cell Lung Cancer (NSCLC)View official trial listing → -
Completed NCT NCT04857138
A Study to Evaluate Safety, Pharmacokinetics and Anti-Tumor Activity of RO7300490, as Single Agent or in Combination With Atezolizumab in Participants With Advanced Solid Tumors
Not yet reported Hoffmann-La Roche 80 participants Est. completion 2024-01-18 11 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Active, not recruiting NCT NCT04857684
SBRT + Atezolizumab + Bevacizumab in Resectable HCC
Not yet reported Massachusetts General Hospital 20 participants Est. completion 2026-12-31 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma, Resectable Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT04862949
Organ-specific Responses to Atezolizumab Plus Bevacizumab in Advanced HCC
CHA University 131 participants Est. completion 2023-03-09 1 siteOther conditions: Advanced Hepatocellular CarcinomaView official trial listing → -
No Longer Available NCT NCT04869501
Expanded Access Study of TJ004309 in Patients With Advanced or Metastatic Cancer
I-Mab Biopharma US Limited 3 sitesOther conditions: CancerView official trial listing → -
Active, not recruiting NCT NCT04873362
A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy
Not yet reported Hoffmann-La Roche 1188 participants Est. completion 2034-10-02 238 sites Stand-aloneOther conditions: Breast CancerView official trial listing → -
Completed NCT NCT04896697
Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors
Not yet reported, Not yet reported Xilio Development, Inc. 125 participants Est. completion 2026-05-18 19 sites Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Completed NCT NCT04898751
Analysis of Reporting of Cutaneous Toxicities Associated With Immune Checkpoint Inhibitors
Johns Hopkins University 2214 participants Est. completion 2020-08-31 1 siteOther conditions: Cutaneous Toxicity From ICI TherapyView official trial listing → -
Terminated NCT NCT04902040
Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies
Not yet reported, Not yet reported M.D. Anderson Cancer Center 19 participants Est. completion 2025-02-27 1 site Stand-aloneOther conditions: Advanced Bladder Carcinoma, Advanced Lung Non-Small Cell Carcinoma, Advanced Malignant Solid Neoplasm, Advanced Melanoma, Advanced Merkel Cell Carcinoma, Advanced Renal Cell Carcinoma, Clinical Stage III Cutaneous Melanoma AJCC v8, Clinical Stage III Merkel Cell Carcinoma AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8, Clinical Stage IV Merkel Cell Carcinoma AJCC v8, Pathologic Stage III Cutaneous Melanoma AJCC v8, Pathologic Stage III Merkel Cell Carcinoma AJCC v8, Pathologic Stage IIIA Cutaneous Melanoma AJCC v8, Pathologic Stage IIIA Merkel Cell Carcinoma AJCC v8, Pathologic Stage IIIB Cutaneous Melanoma AJCC v8, Pathologic Stage IIIB Merkel Cell Carcinoma AJCC v8, Pathologic Stage IIIC Cutaneous Melanoma AJCC v8, Pathologic Stage IIID Cutaneous Melanoma AJCC v8, Pathologic Stage IV Cutaneous Melanoma AJCC v8, Pathologic Stage IV Merkel Cell Carcinoma AJCC v8, Stage III Bladder Cancer AJCC v8, Stage III Lung Cancer AJCC v8, Stage III Renal Cell Cancer AJCC v8, Stage IIIA Bladder Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Bladder Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Bladder Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Stage IVA Bladder Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Bladder Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8View official trial listing → -
Completed NCT NCT04909164
The Prospective Non-randomized Case-control Study From Real-world Lung Cancer Patients
Myung-Ju Ahn 1519 participants Est. completion 2026-07-30 1 siteOther conditions: Non-small Cell Lung Cancer (NSCLC)View official trial listing → -
Terminated NCT NCT04911166
Phase I Trial of Atezolizumab and Interleukin-12 Gene Therapy in Metastatic Non-Small Cell Lung Cancer With Progression on First-Line Immunotherapy With or Without Chemotherapy
Not yet reported The Methodist Hospital Research Institute 13 participants Est. completion 2025-04-01 1 site Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT04919369
All-Trans Retinoic Acid (ATRA) and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer
Not yet reported Dwight Owen 18 participants Est. completion 2026-07-03 1 site Stand-aloneOther conditions: Metastatic Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8View official trial listing → -
Completed NCT NCT04920981
Atezolizumab Combined With Chemotherapy in Extensive Stage SCLC
Intergroupe Francophone de Cancerologie Thoracique 518 participants Est. completion 2024-09-01 2 sitesOther conditions: Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT04923776
Liver Directed RT + Chemo-immunotherapy for ES-SCLC
Not yet reported Brian Henick, MD 2 participants Est. completion 2023-12-23 1 site Stand-aloneOther conditions: Small-cell Lung CancerView official trial listing → -
Completed NCT NCT04924374
Microbiota Transplant in Advanced Lung Cancer Treated With Immunotherapy
Not yet reported Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal 25 participants Est. completion 2023-11-15 1 siteOther conditions: Lung CancerView official trial listing → -
Active, not recruiting NCT NCT04931342
A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors
Not yet reported Hoffmann-La Roche 176 participants Est. completion 2028-05-30 41 sites Stand-aloneOther conditions: Ovarian CancerView official trial listing → -
Terminated NCT NCT04933227
A Study to Explore the Efficacy and Safety of Atezolizumab Plus Tiragolumab and Chemotherapy in 1st Line HER2 Negative Unresectable, Recurrent or Metastatic Gastric Cancer or Adenocarcinoma of Gastroesophageal Junction (GEJ)
Not yet reported Hoffmann-La Roche 29 participants Est. completion 2023-11-17 11 sites Stand-aloneOther conditions: Stomach Neoplasms, Gastric Cancer, Gastroesophageal Junction AdenocarcinomaView official trial listing → -
Completed NCT NCT04939480
Window of Opportunity Study of Preoperative Immunotherapy With Atezolizumab in Local SCCHN
Not yet reported University Hospital, Essen 20 participants Est. completion 2024-03-14 1 site Stand-aloneOther conditions: Squamous Cell Carcinoma of Head and NeckView official trial listing → -
Active, not recruiting NCT NCT04941287
Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer
Not yet reported National Cancer Institute (NCI) 57 participants Est. completion 2026-04-29 29 sites Stand-aloneOther conditions: Metastatic Distal Bile Duct Adenocarcinoma, Metastatic Gallbladder Carcinoma, Metastatic Intrahepatic Cholangiocarcinoma, Recurrent Distal Bile Duct Adenocarcinoma, Recurrent Gallbladder Carcinoma, Recurrent Intrahepatic Cholangiocarcinoma, Stage IV Distal Bile Duct Cancer AJCC v8, Stage IV Gallbladder Cancer AJCC v8, Stage IV Intrahepatic Cholangiocarcinoma AJCC v8, Unresectable Liver CarcinomaView official trial listing → -
Completed NCT NCT04954339
DYNAmic Immune Microenvironment of HCC Treated With atezolIzumab Plus bevaCizumab
Not yet reported Tae Won Kim 40 participants Est. completion 2026-05-26 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT04958811
Tiragolumab With Atezolizumab Plus Bevacizumab in Previously-Treated Advanced Non-squamous NSCLC
Not yet reported Georgetown University 29 participants Est. completion 2027-12 2 sites Stand-aloneOther conditions: Non-squamous Non-small-cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT04962126
Frontline Treatment of Follicular Lymphoma With AtezolizUmab and Obinutuzumab With and Without RadiOtherapy
Not yet reported Olivia Newton-John Cancer Research Institute 15 participants Est. completion 2027-07 3 sites Stand-aloneOther conditions: Follicular LymphomaView official trial listing → -
Terminated NCT NCT04971187
Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung Cancer
Not yet reported M.D. Anderson Cancer Center 3 participants Est. completion 2022-02-21 1 siteOther conditions: Locally Advanced Lung Non-Squamous Non-Small Cell Carcinoma, Metastatic Lung Non-Squamous Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8, Unresectable Lung Non-Squamous Non-Small Cell CarcinomaView official trial listing → -
Completed NCT NCT04975932
Efficacy and Safety of TACE in Combination With ICIs for HCC: a Real-world Study
Zhongda Hospital 826 participants Est. completion 2023-02-08 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT04975958
Double/Triple Combinations of AN2025, AN0025 and Atezolizumab in Advanced Solid Tumors
Not yet reported Adlai Nortye Biopharma Co., Ltd. 47 participants Est. completion 2025-01-24 5 sites Stand-aloneOther conditions: Locally Advanced Solid TumorView official trial listing → -
Terminated NCT NCT04984811
NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLC
Not yet reported NeoImmuneTech 33 participants Est. completion 2024-09-19 22 sites Stand-aloneOther conditions: Carcinoma, Non-Small-Cell Lung, Non-Small Cell Lung Cancer, Non-Small Cell Lung Carcinoma, Nonsmall Cell Lung Cancer, Non Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT04989218
Durvalumab and Tremelimumab With Platinum-based Chemotherapy in Intrahepatic Cholangiocarcinoma (ICC)
Not yet reported, Not yet reported University of Alabama at Birmingham 1 participants Est. completion 2024-05-01 1 siteOther conditions: CholangiocarcinomaView official trial listing → -
Withdrawn NCT NCT04989283
Testing the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy Treatment During Radiation Therapy for Superior Sulcus Non-small Cell Lung Cancer
Not yet reported National Cancer Institute (NCI) Est. completion 2031-05-10 46 sites Stand-aloneOther conditions: Lung Non-Small Cell Carcinoma, Stage IIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Superior Sulcus Lung CarcinomaView official trial listing → -
Status unknown NCT NCT04992715
PD-L1 Expression in Lung Cancer
Not yet reported NanoMab Technology (UK) Limited 15 participants Est. completion 2023-09 1 siteOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT04997382
Chemotherapy Combined with ICIs in First-line Alectinib Failed Patients with ALK-rearranged NSCLC
Not yet reported Hunan Province Tumor Hospital 112 participants Est. completion 2024-01-31 1 site Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT05001347
A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors
Not yet reported I-Mab Biopharma US Limited 25 participants Est. completion 2023-02-08 15 sites Stand-aloneOther conditions: Ovarian Cancer, Head and Neck Cancer, Non Small Cell Lung Cancer, Gastrointestinal Cancer, Triple Negative Breast Cancer, Ovarian CarcinomaView official trial listing → -
Completed NCT NCT05007613
Second-line Cabozantinib and Atezolizumab in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
Not yet reported National Taiwan University Hospital 24 participants Est. completion 2024-12-01 1 site Stand-aloneOther conditions: Esophageal Cancer, Metastatic Cancer, Squamous Cell CarcinomaView official trial listing → -
Withdrawn NCT NCT05007769
Ramucirumab, Atezolizumab and N-803 After Progression on Any Immune Checkpoint Blocker in NSCLC
Not yet reported Washington University School of Medicine Est. completion 2026-04-30 Stand-aloneOther conditions: Non-small Cell Lung Cancer, Non-small Cell Carcinoma, NSCLC, Non Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT05009069
A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer
Not yet reported Hoffmann-La Roche 58 participants Est. completion 2026-11-10 5 sites Stand-aloneOther conditions: Rectal Neoplasms, Rectal CancerView official trial listing → -
Completed NCT NCT05018273
Study of VB10.NEO in Combination With Atezolizumab in Solid Tumors
Not yet reported Nykode Therapeutics ASA 26 participants Est. completion 2024-10-09 12 sites Stand-aloneOther conditions: Solid Tumors, AdultView official trial listing → -
Status unknown NCT NCT05022927
A Phase I Study of ERY974 in Patients With Hepatocellular Carcinoma
Not yet reported Chugai Pharmaceutical 179 participants Est. completion 2025-12-31 11 sites Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Terminated NCT NCT05025514
Retrospective Study of COVID-19 Vaccines in Patients Undergoing Immunotherapy for Cancer.
Centre Hospitalier Universitaire de Nīmes 125 participants Est. completion 2022-09-16 5 sitesOther conditions: Cancer, ImmunotherapyView official trial listing → -
Status unknown NCT NCT05034055
Study of Stereotactic Ablative Radiotherapy(SBRT) Followed by Atezolizumab / Tiragolumab in Treatment-naive Patients With Metastatic Non-small Cell Lung Cancer
Not yet reported Yonsei University 45 participants Est. completion 2023-12 1 site Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Status unknown NCT NCT05038657
Atezolizumab Immunotherapy, in Immunotherapy Naive Patients With Urinary Tract Squamous Cell Carcinoma (UTSCC).
Not yet reported University Hospital Southampton NHS Foundation Trust 36 participants Est. completion 2025-01 1 site Stand-aloneOther conditions: Squamous Cell Carcinoma, Urinary Tract CancerView official trial listing → -
Active, not recruiting NCT NCT05039281
Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 47 participants Est. completion 2027-12-31 1 site Stand-aloneObstructive sleep apnea Other conditions: Recurrent GlioblastomaView official trial listing → -
Terminated NCT NCT05044676
Immune Cells as a New Biomarker of Response in Patients Treated by Immunotherapy for Advanced Hepatocellular Carcinoma
Assistance Publique - Hôpitaux de Paris 4 participants Est. completion 2025-09-22 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05047250
A Study of Atezolizumab in High PD-L1 Expression, Chemotherapy-Naïve Patients With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 60 participants Est. completion 2027-01-29 18 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT05052099
Phase Ib/II Single-arm Study of mFOLFOX6, Bevacizumab and Atezolizumab in Advanced Biliary Tract Cancer
Not yet reported, Not yet reported University Hospital, Essen 20 participants Est. completion 2024-09-18 2 sites Stand-aloneOther conditions: Biliary Tract CancerView official trial listing → -
Completed NCT NCT05053737
Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV Unrelated HNSCC
Not yet reported University of Colorado, Denver 11 participants Est. completion 2024-06-21 4 sites Stand-aloneOther conditions: Squamous Cell Carcinoma of Head and NeckView official trial listing → -
Completed NCT NCT05055947
Efficacy Biomarker Investigation on Extensive Stage Small Cell Lung Cancer
Hunan Province Tumor Hospital 60 participants Est. completion 2021-09-14 1 siteOther conditions: Extensive Stage Small Cell Lung CancerView official trial listing → -
Completed NCT NCT05055999
Tumor Microenvironment Surveillance on Simultaneous Liver Metastases Extensive Stage Small Cell Lung Cancer
Hunan Province Tumor Hospital 60 participants Est. completion 2021-09-01 1 siteOther conditions: Extensive Stage Small Cell Lung CancerView official trial listing → -
Terminated NCT NCT05060003
Tiragolumab Plus Atezolizumab Versus Atezolizumab in the Treatment of Stage II Melanoma Patients Who Are ctDNA-positive Following Resection
Not yet reported Washington University School of Medicine 7 participants Est. completion 2023-11-27 1 site Stand-aloneOther conditions: Stage II MelanomaView official trial listing → -
Active, not recruiting NCT NCT05063552
Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers
Not yet reported, Not yet reported National Cancer Institute (NCI) 430 participants Est. completion 2027-12-15 172 sites Stand-aloneOther conditions: Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Metastatic Head and Neck Squamous Cell Carcinoma, Metastatic Hypopharyngeal Squamous Cell Carcinoma, Metastatic Laryngeal Squamous Cell Carcinoma, Metastatic Lip and Oral Cavity Carcinoma, Metastatic Nasal Cavity Squamous Cell Carcinoma, Metastatic Nasopharyngeal Squamous Cell Carcinoma, Metastatic Pharyngeal Squamous Cell Carcinoma, Metastatic Sinonasal Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma, Recurrent Hypopharyngeal Squamous Cell Carcinoma, Recurrent Laryngeal Squamous Cell Carcinoma, Recurrent Lip and Oral Cavity Squamous Cell Carcinoma, Recurrent Nasopharyngeal Squamous Cell Carcinoma, Recurrent Pharyngeal Squamous Cell Carcinoma, Recurrent Sinonasal Squamous Cell Carcinoma, Stage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8, Stage IV Hypopharyngeal Carcinoma AJCC v8, Stage IV Laryngeal Cancer AJCC v8, Stage IV Lip and Oral Cavity Cancer AJCC v8, Stage IV Nasopharyngeal Carcinoma AJCC v8, Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8, Stage IV Sinonasal Cancer AJCC v8View official trial listing → -
Terminated NCT NCT05069935
FT538 in Combination With Monoclonal Antibodies in Advanced Solid Tumors
Not yet reported Fate Therapeutics 16 participants Est. completion 2023-08-11 4 sites Stand-aloneOther conditions: Solid Tumor, AdultView official trial listing → -
Active, not recruiting NCT NCT05091567
A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer
Not yet reported Hoffmann-La Roche 660 participants Est. completion 2028-02-28 93 sites Stand-aloneOther conditions: Small-Cell Lung CancerView official trial listing → -
Terminated NCT NCT05093608
SELINEXOR in Combination w/Bevacizumab and Atezolizumab in Newly Diagnosed Advanced Hepatocellular Carcinoma
Not yet reported H. Lee Moffitt Cancer Center and Research Institute 2 participants Est. completion 2022-10-12 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05097911
Phase I Study of RNA Oligonucleotide, MTL-CEBPA, Atezolizumab and Bevacizumab in Patients With Advanced Hepatocellular Carcinoma.
Not yet reported National University Hospital, Singapore 33 participants Est. completion 2027-04 1 site Stand-aloneOther conditions: Advanced Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT05101629
Pembrolizumab and Lenvatinib in Patients With Advanced HCC Who Are Refractory to Atezolizumab and Bevacizumab/ IO-based Therapy
Not yet reported Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 32 participants Est. completion 2025-06-30 12 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT05102214
HLX301 (TIGIT×PDL1 Bispecific) in Patients With Locally Advanced or Metastatic Solid Tumors
Not yet reported, Not yet reported Shanghai Henlius Biotech 150 participants Est. completion 2024-02 5 sitesOther conditions: Locally Advanced or Metastatic Solid Tumors, Non-small Cell Lung CancerView official trial listing → -
Withdrawn NCT NCT05109052
Trial of PXS-5505 Combined With First Line Atezolizumab Plus Bevacizumab For Treating Patients With Unresectable Hepatocellular Carcinoma
Not yet reported, Not yet reported University of Rochester Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma, Cancer of LiverView official trial listing → -
Terminated NCT NCT05109442
Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing Cancers
Not yet reported, Not yet reported Affimed GmbH 112 participants Est. completion 2025-06-11 16 sites Stand-aloneOther conditions: Advanced Solid TumorView official trial listing → -
Terminated NCT NCT05110781
Atezolizumab Before Surgery for the Treatment of Regionally Metastatic Head and Neck Squamous Cell Cancer With an Unknown or Historic Primary Site
Not yet reported University of California, Davis 1 participants Est. completion 2023-04-18 1 site Stand-aloneOther conditions: Locally Advanced Cutaneous Squamous Cell Carcinoma of the Head and Neck, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck, Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8View official trial listing → -
Active, not recruiting NCT NCT05112965
An Extension Study in Participants Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study (IMbrella C)
Not yet reported Hoffmann-La Roche 49 participants Est. completion 2027-06-30 17 sites Stand-aloneOther conditions: NeoplasmsView official trial listing → -
Completed NCT NCT05116202
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Melanoma (Morpheus-Melanoma)
Not yet reported, Not yet reported Hoffmann-La Roche 110 participants Est. completion 2024-05-28 14 sites Stand-aloneOther conditions: MelanomaView official trial listing → -
Active, not recruiting NCT NCT05118724
Atezolizumab in Patients With MSI-h/MMR-D Stage II High Risk and Stage III Colorectal Cancer Ineligible for Oxaliplatin
Not yet reported AIO-Studien-gGmbH 80 participants Est. completion 2027-04 1 site Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Status unknown NCT NCT05134532
Regorafenib After Progression on Atezolizumab Plus Bevacizumab in Advanced HCC
Not yet reported CHA University 40 participants Est. completion 2024-10-30 2 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT05137899
Neoadjuvant Combination of Atezolizumab/Bevacizumab Versus Neoadjuvant Radiation Therapy
Not yet reported Ontario Clinical Oncology Group (OCOG) 1 participants Est. completion 2025-02-26 7 sites Stand-aloneOther conditions: Hepatocellular Carcinoma, Portal Vein Tumour ThrombosisView official trial listing → -
Active, not recruiting NCT NCT05141721
A Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer
Not yet reported, Not yet reported Seattle Project Corporation 700 participants Est. completion 2027-03 43 sites Stand-aloneOther conditions: Colorectal NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT05142696
A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab
Not yet reported, Not yet reported Novartis Pharmaceuticals 55 participants Est. completion 2028-03-07 27 sites Stand-aloneOther conditions: Extensive Stage Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT05152472
A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments
Not yet reported Centre Leon Berard 58 participants Est. completion 2027-10 13 sites Stand-aloneOther conditions: Unresectable Gastrointestinal Stromal Tumor (GIST), Locally Advanced Gastrointestinal Stromal Tumor (GIST), Metastatic Gastrointestinal Stromal TumorView official trial listing → -
Active, not recruiting NCT NCT05168618
Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Not yet reported University of Utah 31 participants Est. completion 2027-11 1 site Stand-aloneOther conditions: Castration-Resistant Prostate Carcinoma, Metastatic Prostate Adenocarcinoma, Stage IV Prostate Cancer AJCC v8, Stage IVA Prostate Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8View official trial listing → -
Completed NCT NCT05171777
A Study to Evaluate Participant and Healthcare Professional Reported Preference for Subcutaneous Atezolizumab Compared With Intravenous Atezolizumab Formulation in Participants With Non-Small Cell Lung Cancer
Not yet reported Hoffmann-La Roche 179 participants Est. completion 2024-10-25 36 sites Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Status unknown NCT NCT05173298
Predictive Biomarkers in Patients With Advanced Hepatocellular Carcinoma Treated With Atezolizumab Plus Bevacizumab
CHA University 100 participants Est. completion 2024-12-31 1 siteOther conditions: Advanced Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05174650
Treatment of Atezolizumab and Derazantinib in Patients With Advanced iCCA With FGFR2 Fusions/Rearrangements
Not yet reported Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 27 participants Est. completion 2026-08 17 sites Stand-aloneOther conditions: Intrahepatic CholangiocarcinomaView official trial listing → -
Terminated NCT NCT05180006
Impact of Neoadjuvant Immunotherapy in Early Stage Breast Cancer Before Standard Therapy
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 33 participants Est. completion 2024-12-17 1 site Stand-aloneOther conditions: Breast CancerView official trial listing → -
Enrolling by invitation NCT NCT05185505
Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients With Hepatocellular Carcinoma Beyond Milan Criteria
Not yet reported The Methodist Hospital Research Institute 24 participants Est. completion 2028-10-31 2 sites Stand-aloneOther conditions: Hepatocellular Carcinoma, Hepatocellular CancerView official trial listing → -
Terminated NCT NCT05191797
Bomedemstat and Maintenance Immunotherapy for Treatment of Newly Diagnosed Extensive Stage Small Cell Lung Cancer
Not yet reported, Not yet reported University of Washington 3 participants Est. completion 2024-04-05 1 site Stand-aloneOther conditions: Extensive Stage Lung Small Cell Carcinoma, Limited Stage Lung Small Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05195619
Personalized DC Vaccines in Non Small Cell Lung Cancer
Not yet reported Centre Hospitalier Universitaire Vaudois 16 participants Est. completion 2027-06 1 site Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT05197504
Predictive Biomarkers in Patients With Advanced Hepatocellular Carcinoma Treated With Systemic Therapy
CHA University 166 participants Est. completion 2023-12-31 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT05199285
A Phase II Study of Nivolumab + Ipilimumab in Advanced HCC Patients Who Have Progressed on First Line Atezolizumab + Bevacizumab
Not yet reported Academic and Community Cancer Research United 15 participants Est. completion 2026-02-01 5 sitesOther conditions: BCLC Stage B Hepatocellular Carcinoma, BCLC Stage C Hepatocellular Carcinoma, Locally Advanced Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma, Stage III Hepatocellular Carcinoma AJCC v8, Stage IIIA Hepatocellular Carcinoma AJCC v8, Stage IIIB Hepatocellular Carcinoma AJCC v8, Stage IV Hepatocellular Carcinoma AJCC v8, Stage IVA Hepatocellular Carcinoma AJCC v8, Stage IVB Hepatocellular Carcinoma AJCC v8, Unresectable Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05211323
A Study to Determine Whether Chemotherapy and Atezolizumab is Better Than Chemotherapy, Bevacizumab and Atezolizumab in Patients With Advanced Liver Cancer
Not yet reported National Cancer Institute (NCI) 4 participants Est. completion 2027-08-10 37 sites Stand-aloneOther conditions: Combined Hepatocellular Carcinoma and Cholangiocarcinoma, Stage III Liver Cancer, Stage IV Liver CancerView official trial listing → -
Active, not recruiting NCT NCT05222932
Oncolytic Adenovirus TILT-123 and Avelumab for Treatment of Solid Tumors Refractory to or Progressing After Anti-PD(L)1
Not yet reported TILT Biotherapeutics Ltd. 15 participants Est. completion 2026-12 2 sitesOther conditions: Melanoma, Head and Neck Squamous Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05224141
Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008)
Not yet reported Merck Sharp & Dohme LLC 460 participants Est. completion 2027-06-07 140 sitesOther conditions: Small Cell Lung CarcinomaView official trial listing → -
Withdrawn NCT NCT05238831
SMMART Adaptive Clinical Treatment (ACT) Trial
Not yet reported OHSU Knight Cancer Institute Est. completion 2026-05-31 Stand-aloneOther conditions: Advanced Breast Carcinoma, Advanced Malignant Solid Neoplasm, Advanced Ovarian Carcinoma, Advanced Pancreatic Carcinoma, Advanced Prostate Carcinoma, Advanced Sarcoma, Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8, Recurrent Adult Soft Tissue Sarcoma, Recurrent Breast Carcinoma, Recurrent Ovarian Carcinoma, Recurrent Prostate Carcinoma, Stage II Pancreatic Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage III Pancreatic Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8View official trial listing → -
Status unknown NCT NCT05240131
A Study to Investigate the Safety and Efficacy of GB1211 (a Galectin-3 Inhibitor) in Combination With Atezolizumab in Patients With Non-Small Cell Lung Cancer (NSCLC).
Not yet reported, Not yet reported Galecto Biotech AB 88 participants Est. completion 2025-11-01 5 sites Stand-aloneOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Completed NCT NCT05243862
Safety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.
Not yet reported Treos Bio Limited 18 participants Est. completion 2025-01-14 3 sites Stand-aloneOther conditions: Colorectal Cancer MetastaticView official trial listing → -
Completed NCT NCT05249426
A Study to Test Whether Different Combinations of BI 765063, Ezabenlimab, Chemotherapy, Cetuximab, and BI 836880 Help People With Head and Neck Cancer or Liver Cancer
Not yet reported Boehringer Ingelheim 48 participants Est. completion 2026-06-22 25 sites Stand-aloneOther conditions: Head and Neck Squamous Cell Carcinoma (HNSCC)View official trial listing → -
Terminated NCT NCT05251948
An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junction Carcinoma
Not yet reported, Not yet reported Hoffmann-La Roche 40 participants Est. completion 2025-09-04 11 sites Stand-aloneOther conditions: Gastric and Gastroesophageal Junction CarcinomaView official trial listing → -
Completed NCT NCT05253053
To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors
Not yet reported, Not yet reported TransThera Sciences (Nanjing), Inc. 84 participants Est. completion 2024-08-31 9 sites Stand-aloneOther conditions: Advanced Solid Tumor, Cholangiocarcinoma, Biliary Tract Cancer, HER2-negative Breast Cancer, Triple Negative Breast Cancer, Small-cell Lung Cancer, Bladder Cancer, Prostate Cancer, Thyroid Cancer, Gastric Cancer, Gallbladder CancerView official trial listing → -
Status unknown NCT NCT05259319
Study Evaluating the Safety and the Efficacy of Combination of Atezolizumab, Tiragolumab and and Stereotactic Body Radiation Therapy in Patients With Oligometastatic Multiorgan (IMMUNOs-SBRT)
Not yet reported Centre Georges Francois Leclerc 92 participants Est. completion 2024-12-05 1 site Stand-aloneOther conditions: Metastatic Non Small Cell Lung Cancer, Metastatic Bladder Cancer, Metastatic Renal Cell Carcinoma, Metastatic Head and Neck CancerView official trial listing → -
Status unknown NCT NCT05260606
Imaging Biomarkers for Immune Checkpoint Inhibitor Treatment in Patients With Non-small Cell Lung Cancer
Samsung Medical Center 100 participants Est. completion 2025-12 1 siteOther conditions: Carcinoma, Non-Small-Cell Lung, Immune Checkpoint InhibitorsView official trial listing → -
Completed NCT NCT05261438
Atezolizumab Plus Bevacizumab and Chemotherapy in First-Line Metastatic Nonsquamous NSCLC
Hunan Province Tumor Hospital 70 participants Est. completion 2021-09-15 1 siteOther conditions: Non-squamous NSCLCView official trial listing → -
Status unknown NCT NCT05266937
Atezolizumab Plus CArboplatin Plus Nab-paclitaxel
Not yet reported Consorzio Oncotech 49 participants Est. completion 2024-07-03 15 sites Stand-aloneOther conditions: Metastatic Breast Cancer, Triple Negative Breast Cancer, PD-L1 Gene MutationView official trial listing → -
Completed NCT NCT05276284
Thiopurine Enhanced Mutations for PD-1/Ligand-1 Efficacy
Not yet reported, Not yet reported Kristoffer Rohrberg 18 participants Est. completion 2025-09-01 1 site Stand-aloneOther conditions: Solid Tumor, Adult, Metastatic CancerView official trial listing → -
Active, not recruiting NCT NCT05286801
Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors
Not yet reported, Not yet reported National Cancer Institute (NCI) 86 participants Est. completion 2030-03-31 40 sites Stand-aloneOther conditions: Atypical Teratoid/Rhabdoid Tumor, Epithelioid Sarcoma, Kidney Medullary Carcinoma, Malignant Solid Neoplasm, Poorly Differentiated Chordoma, Recurrent Atypical Teratoid/Rhabdoid Tumor, Recurrent Chordoma, Recurrent Epithelioid Sarcoma, Recurrent Kidney Medullary Carcinoma, Recurrent Malignant Solid Neoplasm, Recurrent Rhabdoid Tumor, Refractory Atypical Teratoid/Rhabdoid Tumor, Refractory Chordoma, Refractory Epithelioid Sarcoma, Refractory Kidney Medullary Carcinoma, Refractory Malignant Solid Neoplasm, Refractory Rhabdoid Tumor, Rhabdoid TumorView official trial listing → -
Status unknown NCT NCT05295212
Atezolizumab Combined With Platinum-based Chemotherapy as Neoadjuvant Therapy for Patients With Resectable Stage II-IIIB
Not yet reported Hunan Province Tumor Hospital 120 participants Est. completion 2025-07-01 1 site Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT05300282
Study of Atezolizumab Plus BEGEV Regimen in Relapsed or Refractory Hodgkin's Lymphoma Patients
Not yet reported, Not yet reported Fondazione Italiana Linfomi - ETS 122 participants Est. completion 2029-12-15 28 sites Stand-aloneOther conditions: Relapsed or Refractory Hodgkin's LymphomaView official trial listing → -
Terminated NCT NCT05315713
An Open-Label, Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab in Combination With Tiragolumab With or Without Atezolizumab in Participants With B-Cell Non-Hodgkin Lymphoma
Not yet reported, Not yet reported Hoffmann-La Roche 8 participants Est. completion 2023-07-19 17 sites Stand-aloneOther conditions: Non-Hodgkin Lymphoma, Follicular LymphomaView official trial listing → -
Status unknown NCT NCT05325684
PD-L1 Inhibitor Rechallenge After PD-1 Immunotherapy for Patients With Solid Tumor Beyond Lung Cancer
Not yet reported, Not yet reported The Affiliated Hospital of Qingdao University 30 participants Est. completion 2023-12 Stand-aloneOther conditions: Efficacy, SafetyView official trial listing → -
Withdrawn NCT NCT05327738
Yttrium Y 90 Glass Microspheres, Atezolizumab, and Cabozantinib for the Treatment of Unresectable or Locally Advanced Hepatocellular Carcinoma
Not yet reported OHSU Knight Cancer Institute Est. completion 2027-12-04 Stand-aloneOther conditions: BCLC Stage B Hepatocellular Carcinoma, BCLC Stage C Hepatocellular Carcinoma, Locally Advanced Hepatocellular Carcinoma, Recurrent Hepatocellular Carcinoma, Unresectable Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT05332496
TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for Intermediate HCC
Zhongda Hospital 941 participants Est. completion 2025-09-14 2 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT05332821
TACE in Combination With PD-1/PD-L1 Inhibitors and Molecular Target Therapies for Advanced HCC
Zhongda Hospital 1244 participants Est. completion 2024-01-10 2 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05334329
Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors
Not yet reported University of California, Irvine 6 participants Est. completion 2028-11-30 1 site Stand-aloneOther conditions: Advanced Lung Non-Small Cell Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Refractory Lung Non-Small Cell Carcinoma, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8View official trial listing → -
Active, not recruiting NCT NCT05340309
Subcutaneous Atezolizumab for the Treatment of Non-small Cell Lung Cancer
Not yet reported University of Southern California 5 participants Est. completion 2027-12-31 1 site Stand-aloneOther conditions: Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage III Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Stage IIIC Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8View official trial listing → -
Terminated NCT NCT05359861
Trial of Atezolizumab and Bevacizumab With CHS-388 or Placebo in Patients With Hepatocellular Carcinoma
Not yet reported Coherus Oncology, Inc. 30 participants Est. completion 2025-07-08 37 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05361395
First-Line Tarlatamab in Combination With Carboplatin, Etoposide, and PD-L1 Inhibitor in Subjects With Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Not yet reported Amgen 184 participants Est. completion 2030-05-30 44 sites Stand-aloneOther conditions: Extensive Stage Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT05377034
Multinational Phase II Trial to Compare Safety and Efficacy of SIRT (Y-90 Resin Microspheres) Followed by Atezolizumab Plus Bevacizumab, vs SIRT (SIRT-Y90) Followed by Placebo in Locally Advanced HCC Patients
Not yet reported National Cancer Centre, Singapore 119 participants Est. completion 2028-05-06 14 sites Stand-aloneOther conditions: Locally Advanced Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT05390528
A Study Evaluating the Safety, Tolerability, Pharmacokinetic and Efficacy of HLX301(TIGIT×PDL1 Bispecific) in Locally Advanced/Metastatic Solid Tumors or Lymphoma
Not yet reported, Not yet reported Shanghai Henlius Biotech 30 participants Est. completion 2024-12-30 2 sitesOther conditions: Advanced Tumors, Lymphoma, Metastatic TumorsView official trial listing → -
Terminated NCT NCT05393713
Intra-Lymphatic STI-3031 Using the Sofusa DoseConnect Device for Treatment of In-Transit Melanoma, The Sofusa-2 Study
Not yet reported Mayo Clinic 3 participants Est. completion 2025-02-16 2 sitesOther conditions: Clinical Stage III Cutaneous Melanoma AJCC v8, Melanoma, Metastatic Melanoma, Recurrent Metastatic MelanomaView official trial listing → -
Active, not recruiting NCT NCT05394337
Neoadjuvant PD-1 Plus TIGIT Blockade in Patients With Cisplatin-Ineligible Operable High-Risk Urothelial Carcinoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center 10 participants Est. completion 2028-12-31 1 site Stand-aloneOther conditions: Metastatic MalignancyView official trial listing → -
Terminated NCT NCT05395052
FT536 Monotherapy and in Combination With Monoclonal Antibodies in Advanced Solid Tumors
Not yet reported Fate Therapeutics 5 participants Est. completion 2023-08-11 5 sites Stand-aloneOther conditions: Non Small Cell Lung Cancer, Colorectal Cancer, Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Head and Neck Cancer, GastroEsophageal CancerView official trial listing → -
Status unknown NCT NCT05396937
Efficacy and Safety of T+A+RAD in HCC
Not yet reported Fudan University 42 participants Est. completion 2023-12 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT05402059
Clinical Outcomes and Biomarkers in Patients With Stage 0-IV Melanoma in Real Clinical Practice
MelanomaPRO, Russia 1570 participants Est. completion 2025-04 1 siteOther conditions: Melanoma, Melanoma (Skin), Melanoma, Uveal, Melanoma Stage IV, Melanoma Stage III, Melanoma, Stage II, Melanoma in Situ, Melanoma, OcularView official trial listing → -
Active, not recruiting NCT NCT05404048
PD-L1 PET-imaging During CAR T-cell Therapy
Not yet reported University Medical Center Groningen 20 participants Est. completion 2026-05 1 site Stand-aloneOther conditions: Large B-cell LymphomaView official trial listing → -
Active, not recruiting NCT NCT05411081
Testing Cabozantinib With or Without Atezolizumab in Patients With Advanced Papillary Kidney Cancer, PAPMET2 Trial
Not yet reported National Cancer Institute (NCI) 200 participants Est. completion 2027-07-01 198 sites Stand-aloneOther conditions: Metastatic Papillary Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v8View official trial listing → -
Completed NCT NCT05411133
Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients
Not yet reported Arbele Pty Ltd 33 participants Est. completion 2025-07-23 3 sites Stand-aloneOther conditions: Gastrointestinal Cancer, Cholangiocarcinoma, Liver Cancer, Colorectal Adenocarcinoma, Pancreatic Cancer, Gastric Cancer, Esophageal Adenocarcinoma, Gastroesophageal Junction, Gastrointestinal Neuroendocrine TumorsView official trial listing → -
Status unknown NCT NCT05418660
Observational Retro-prospective Study on PD1/PDL1 Inhibitors Treatment Duration in Patients With NSCLC
University of Milano Bicocca 300 participants Est. completion 2024-11-30 10 sitesOther conditions: Non-small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT05425940
Study of XL092 + Atezolizumab vs Regorafenib in Participants With Metastatic Colorectal Cancer
Not yet reported Exelixis 901 participants Est. completion 2027-01-31 133 sites Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Status unknown NCT NCT05429866
Immunological Variables Associated to ICI Toxicity in Cancer Patients
Not yet reported Jules Bordet Institute 441 participants Est. completion 2024-12-01 1 siteOther conditions: Breast Cancer, Melanoma, Non Small Cell Lung Cancer, Non-melanoma Skin Cancer, Gastrointestinal Cancer, Head and Neck Cancer, Renal Cell Carcinoma, Small Cell Lung Cancer, Mesothelioma, Malignant, Bladder Cancer, Merkel Cell Carcinoma, Hepatocellular Carcinoma, MSI-H Colorectal CancerView official trial listing → -
Enrolling by invitation NCT NCT05441475
A Phase 2, Open-Label Study of ABSK-011 Combined Atezolizumab or SOC in HCC Patients
Not yet reported Abbisko Therapeutics Co, Ltd 118 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT05448677
Ezurpimtrostat Autophagy Inhibitor in Association With Atezolizumab-Bevacizumab in First Line Treatment of Unresectable Hepatocellular Carcinoma
Not yet reported University Hospital, Grenoble 3 participants Est. completion 2024-03-08 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT05450562
Dose Escalation and Expansion Study of SAR444200-based Regimen in Adult Participants With Advanced Solid Tumors
Not yet reported, Not yet reported Sanofi 33 participants Est. completion 2025-12-22 13 sites Stand-aloneOther conditions: NeoplasmView official trial listing → -
Withdrawn NCT NCT05456165
Study of an Individualized Vaccine Targeting Neoantigens in Combination With Immune Checkpoint Blockade for Patients With Colon Cancer
Not yet reported Gritstone bio, Inc. Est. completion 2022-09-01 3 sites Stand-aloneOther conditions: Colonic Neoplasms, Colorectal NeoplasmsView official trial listing → -
Completed NCT NCT05459129
A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)
Not yet reported, Not yet reported Hoffmann-La Roche 12 participants Est. completion 2024-08-15 6 sites Stand-aloneOther conditions: Squamous Cell Carcinoma of the Head and NeckView official trial listing → -
Active, not recruiting NCT NCT05468489
To Evaluate Efficacy and Safety of Serplulimab + Chemotherapy (Carboplatin- Etoposide) in US Patients With ES-SCLC
Not yet reported Shanghai Henlius Biotech 200 participants Est. completion 2027-12-31 67 sitesOther conditions: Extensive Stage Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT05470595
A Single-arm Trial of Atezolizumab/Platinum/Etoposide for the Treatment of Advanced Large-cell Neuroendocrine Cancer of the Lung
Not yet reported Technische Universität Dresden 67 participants Est. completion 2029-01-31 15 sites Stand-aloneOther conditions: Large Cell Neuroendocrine Carcinoma of the LungView official trial listing → -
Active, not recruiting NCT NCT05482516
Evaluating Novel Therapies in ctDNA Positive GI Cancers
Not yet reported Georgetown University 11 participants Est. completion 2027-12 1 site Stand-aloneOther conditions: Colon Adenocarcinoma, Rectal Adenocarcinoma, Gastric Adenocarcinoma, Pancreatic Adenocarcinoma, Hepatocellular Carcinoma, Adenocarcinoma of Biliary Tract, Gallbladder AdenocarcinomaView official trial listing → -
Completed NCT NCT05487235
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Genentech, Inc. 57 participants Est. completion 2025-06-23 25 sites Stand-aloneOther conditions: Advanced Solid Tumors, Metastatic Solid TumorsView official trial listing → -
Active, not recruiting NCT NCT05498896
Investigate the Contribution of Ipatasertib to Neoadjuvant Chemotherapy Plus Atezolizumab in TNBC
Not yet reported Queen Mary University of London 146 participants Est. completion 2026-08-31 1 site Stand-aloneOther conditions: Triple Negative Breast CancerView official trial listing → -
Withdrawn NCT NCT05510427
Phase Ib Trial of Infigratinib In Combination With Atezolizumab And Bevacizumab for The Second-Line Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion/Amplification
Not yet reported M.D. Anderson Cancer Center Est. completion 2023-08-07 Stand-aloneOther conditions: Cholangiocarcinoma, Liver CancerView official trial listing → -
Active, not recruiting NCT NCT05515627
Atezolizumab for Idiopathic Pulmonary Fibrosis
Not yet reported Cedars-Sinai Medical Center 24 participants Est. completion 2027-04-30 1 site Stand-aloneOther conditions: Idiopathic Pulmonary FibrosisView official trial listing → -
Active, not recruiting NCT NCT05525858
KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II
Seoul National University Bundang Hospital 1000 participants Est. completion 2027-03-31 32 sitesOther conditions: Solid Tumor, Advanced Solid Tumor, Metastatic CancerView official trial listing → -
Terminated NCT NCT05537402
LOcoregional vs Systemic Therapy in Patients With BCLC Stage B HCC
Not yet reported University of Texas Southwestern Medical Center 1 participants Est. completion 2025-06-06 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05546879
Study Investigating the Association of NP137 With Atezolizumab-Bevacizumab Combination in First Line in Unresectable HCC
Not yet reported University Hospital, Grenoble 43 participants Est. completion 2029-03-19 9 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Withdrawn NCT NCT05564416
Testing Anti-Cancer Drugs Erdafitinib With or Without Atezolizumab in Patients With Localized Bladder Cancer Not Able to Receive Cisplatin Chemotherapy, NERA Trial
Not yet reported National Cancer Institute (NCI) Est. completion 2024-01-01 Stand-aloneOther conditions: Bladder Carcinoma, Bladder Urothelial Carcinoma, Muscle Invasive Bladder Carcinoma, Renal Pelvis and Ureter Urothelial Carcinoma, Stage II Bladder Cancer AJCC v8, Stage III Bladder Cancer AJCC v8, Stage IVA Bladder Cancer AJCC v8, Urothelial CarcinomaView official trial listing → -
Status unknown NCT NCT05573282
Observation Study of Sequential Regorafenib Plus ICIs After HAIC for Advanced Hepatocellular Carcinoma
Sun Yat-sen University 50 participants Est. completion 2026-01-01 2 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05581004
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Genentech, Inc. 165 participants Est. completion 2028-07-31 36 sites Stand-aloneOther conditions: Locally Advanced or Metastatic Solid Tumors, NSCLC, HNSCC, Melanoma, TNBC, Esophageal Cancer, Gastric Cancer, Cervical Cancer, Colorectal Cancer, Urothelial Carcinoma, Clear Cell RCC, HCCView official trial listing → -
Active, not recruiting NCT NCT05595460
Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC
Not yet reported RayzeBio, Inc. 21 participants Est. completion 2027-07 13 sites Stand-aloneOther conditions: SCLC,Extensive StageView official trial listing → -
Completed NCT NCT05609903
Atezolizumab With Nab-paclitaxel for Patients With Triple-negative Stage IV Breast Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 52 participants Est. completion 2022-05-31 1 siteOther conditions: Breast Cancer MetastaticView official trial listing → -
Completed NCT NCT05625893
Proton Beam Radiotherapy Followed by Tecentriq and Avastin for Primary Liver Cancer With Vp2-4 Portal Vein Invasion
Not yet reported Samsung Medical Center 63 participants Est. completion 2026-03-30 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma, Portal Vein ThrombosisView official trial listing → -
Active, not recruiting NCT NCT05645692
A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer
Not yet reported Hoffmann-La Roche 204 participants Est. completion 2026-12-31 56 sitesOther conditions: Urothelial CancerView official trial listing → -
Status unknown NCT NCT05655663
Evaluation of Vascular Toxicity of Immune Checkpoint Inhibitors in Patients Head and Neck or Lung Cancer
Not yet reported Centre Henri Becquerel 30 participants Est. completion 2025-12-20 2 sitesOther conditions: Head and Neck Cancer, Lung CancerView official trial listing → -
Completed NCT NCT05661188
Tiraglolumab Atezolizumab and Chemoradiotherapy in Localized Anal Carcinoma (TIRANUS)
Not yet reported Grupo Espanol Multidisciplinario del Cancer Digestivo 45 participants Est. completion 2026-09-25 13 sites Stand-aloneOther conditions: Squamous Cell Carcinoma of the Anal CanalView official trial listing → -
Completed NCT NCT05661578
A Study to Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors
Not yet reported Hoffmann-La Roche 64 participants Est. completion 2025-12-26 32 sites Stand-aloneOther conditions: PD-L1-selected Solid TumorsView official trial listing → -
Completed NCT NCT05665348
Study Evaluating the Benefit of Adding Ipilimumab to the Combination of Atezolizumab and Bevacizumab in Patients With Hepatocellular Carcinoma Receiving First-line Systemic Therapy
Not yet reported, Not yet reported Federation Francophone de Cancerologie Digestive 229 participants Est. completion 2025-05-12 45 sites Stand-aloneOther conditions: HCC - Hepatocellular Carcinoma, Metastatic Cancer, Metastatic TumorView official trial listing → -
Active, not recruiting NCT NCT05681039
Phase 2 Trial of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab in Patients With Newly Diagnosed PD-L1 CPS Positive Resectable Stage 3-4 Oral Cavity Squamous Cell Carcinoma (OCSCC).
Not yet reported M.D. Anderson Cancer Center 29 participants Est. completion 2026-11-01 1 site Stand-aloneOther conditions: Squamous Cell Carcinoma, Oral Cavity Squamous Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05689671
Pemetrexed-free vs. Pemetrexed-based Immunochemotherapy in Metastatic TTF-1 Negative Lung Adenocarcinoma
Not yet reported Nikolaj Frost MD 136 participants Est. completion 2026-10 36 sites Stand-aloneOther conditions: Non-Small Cell Lung Cancer MetastaticView official trial listing → -
Terminated NCT NCT05694013
Clinical Impact and Utility of Digital Health Solutions in Participants Receiving Systemic Treatment in Clinical Practice
Not yet reported, Not yet reported Hoffmann-La Roche 49 participants Est. completion 2024-06-30 14 sites Stand-aloneOther conditions: CancerView official trial listing → -
Not yet recruiting NCT NCT05703997
FASTing-like Approach and Maintenance IMMunotherapy in ES-SCLC Patients Not Progressing on Chemoimmunotherapy Induction
Not yet reported Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 20 participants Est. completion 2029-01 1 site Stand-aloneOther conditions: Small Cell Lung CarcinomaView official trial listing → -
Terminated NCT NCT05705791
Clinical Investigation Evaluating Safety and Efficacy of Selective Intra-arterial 166Holmium Radiation Therapy in Combination With Atezolizumab and Bevacizumab for Non Resectable Hepatocellular Carcinoma
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris 10 participants Est. completion 2025-12-24 6 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05715281
Testing the Combination of Anti-cancer Drugs Atezolizumab and Tiragolumab in People With Advanced Stage Rare Cancers, RARE3 Trial
Not yet reported National Cancer Institute (NCI) 12 participants Est. completion 2026-11-21 3 sites Stand-aloneOther conditions: Advanced Rare Malignant Solid Neoplasm, Rare Malignant Solid Neoplasm, Refractory Rare Malignant Solid NeoplasmView official trial listing → -
Terminated NCT NCT05717400
Improving Response to Immunotherapy in Patients With Advanced Hepatocellular Carcinoma and Chronic Hepatitis C Virus Infection With Direct-Acting Antiviral Therapy
Not yet reported M.D. Anderson Cancer Center 2 participants Est. completion 2024-08-29 1 site Stand-aloneOther conditions: Liver CancerView official trial listing → -
Status unknown NCT NCT05717738
Combined TACE, TKI/Anti-VEGF and ICIs as Conversion Therapy for Advanced Hepatocellular Carcinoma
Tongji Hospital 300 participants Est. completion 2024-12-31 4 sitesOther conditions: Hepatocellular Carcinoma Non-resectableView official trial listing → -
Terminated NCT NCT05733611
RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC
Not yet reported Replimune, Inc. 5 participants Est. completion 2025-08-18 2 sites Stand-aloneOther conditions: Refractory Metastatic Colorectal Cancer, pMMR, MSSView official trial listing → -
Terminated NCT NCT05742269
Molecular PD-L1 PET/CT Imaging With 89Zr-atezolizumab in Metastatic Triple Negative Breast Cancer
Karolinska University Hospital 3 participants Est. completion 2026-03-11 1 siteOther conditions: Metastatic Triple-Negative Breast CarcinomaView official trial listing → -
Status unknown NCT NCT05743504
Immunotherapy With CCRT Followed by Surgery for Locally Advanced ESCC Patients
Not yet reported, Not yet reported National Taiwan University Hospital 32 participants Est. completion 2025-11-30 1 site Stand-aloneOther conditions: Locally Advanced Esophageal Squamous Cell CarcinomaView official trial listing → -
Terminated NCT NCT05746481
Tiragolumab and Atezolizumab in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC) and Untreated Brain Metastases
Not yet reported Liza Villaruz, MD 3 participants Est. completion 2025-11-08 1 site Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Completed NCT NCT05750030
FMT in IT-refractory HCC - FAB-HCC Pilot Study
Not yet reported Medical University of Vienna 12 participants Est. completion 2025-03-17 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT05756907
Combination of SON-1010 (IL12-FHAB) and Atezolizumab in Patients With Platinum-resistant Ovarian Cancer
Not yet reported, Not yet reported Sonnet BioTherapeutics 40 participants Est. completion 2026-01-08 6 sites Stand-aloneOther conditions: Advanced Solid Tumor, Platinum-resistant Ovarian CancerView official trial listing → -
Status unknown NCT NCT05760599
Candonilimab Plus Bevacizumab for Patients With Advanced HCC Who Progressed on A+T
Not yet reported Shi Ming 30 participants Est. completion 2024-07-01 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Withdrawn NCT NCT05774886
Implantable Microdevice for TNBC - Pilot Study
Not yet reported Dana-Farber Cancer Institute Est. completion 2028-09-01 Stand-aloneOther conditions: Triple Negative Breast Cancer, Breast Cancer Stage II, Breast Cancer Stage III, Breast Cancer, Early Stage Triple-Negative Breast Carcinoma, Breast Neoplasms, Breast CarcinomaView official trial listing → -
Terminated NCT NCT05776875
Atezolizumab and Bevacizumab in Combination With TACE for Patients With BCLC B HCC
Not yet reported Yale University 3 participants Est. completion 2024-12-05 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma, BCLC Stage B Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05781308
Combination of Paclitaxel-bevacizumab ± Atezolizumab in Patients With Advanced NSCLC Progressing After Immunotherapy & Chemotherapy
Not yet reported Intergroupe Francophone de Cancerologie Thoracique 156 participants Est. completion 2026-06 44 sites Stand-aloneOther conditions: Non Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT05798663
Atezolizumab Immunotherapy With or Without Tiragolumab for Patients With Unresectable Stage III NSCLC
Not yet reported Alliance Foundation Trials, LLC. 178 participants Est. completion 2027-02 15 sites Stand-aloneOther conditions: NSCLCView official trial listing → -
Completed NCT NCT05809336
Gut Microbial Metabolites Inosine Combined With PD-1/PD-L1 Inhibitor for Patients With Malignant Advanced Solid Tumors
Not yet reported, Not yet reported Beijing Friendship Hospital 172 participants Est. completion 2022-10-31 1 siteOther conditions: Advanced Solid TumorView official trial listing → -
Active, not recruiting NCT NCT05825625
NeoTRACK - Dissection of IO Efficacy in NSCLC by Longitudinal tracKing
Not yet reported Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 35 participants Est. completion 2027-06-01 2 sites Stand-aloneOther conditions: Non-small Cell Lung CancerView official trial listing → -
Status unknown NCT NCT05831553
TIP in Patients Affected by Metastatic TNBC
Fondazione per la Medicina Personalizzata 100 participants Est. completion 2025-09-16 6 sitesOther conditions: Metastatic Triple-negative Breast CancerView official trial listing → -
Status unknown NCT NCT05833126
Hepatic Arterial Infusion Chemotherapy in Combination With Atezolizumab and Bevacizumab for Second-line Treatment of Patients With Recurrent Liver Cancer After Liver Transplantation
Not yet reported Shuhong Yi 25 participants Est. completion 2025-04-01 1 site Stand-aloneOther conditions: Recurrent Liver Cancer After Liver TransplantationView official trial listing → -
Completed NCT NCT05834348
A Study to Learn About the Effectiveness of Cancer Medicines in Patients With Metastatic Non-small Cell Lung Cancer in Norway.
Pfizer 5279 participants Est. completion 2024-01-23 1 siteOther conditions: Non-Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT05836584
Testing Immunotherapy (Atezolizumab) With or Without Chemotherapy in Locoregional MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) Cancer
Not yet reported National Cancer Institute (NCI) 2 participants Est. completion 2027-06-28 133 sites Stand-aloneOther conditions: Clinical Stage I Gastric Cancer AJCC v8, Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage II Gastric Cancer AJCC v8, Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage III Gastric Cancer AJCC v8, Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8, Clinical Stage IVA Gastric Cancer AJCC v8, Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8, Gastric Adenocarcinoma, Gastroesophageal Junction AdenocarcinomaView official trial listing → -
Not yet recruiting NCT NCT05859217
A Study of Combining Cabozantinib and Atezolizumab for Advanced/Metastatic NSCLC (Cabatezo-1)
Not yet reported Jun Zhang, MD, PhD 40 participants Est. completion 2028-06 4 sites Stand-aloneOther conditions: Lung Cancer, NSCLC Stage IV, Metastatic NSCLC - Non-Small Cell Lung Cancer, Advanced NSCLCView official trial listing → -
Completed NCT NCT05867121
A Study to Evaluate Safety, Pharmacokinetics, & Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors; Urothelial Carcinoma Substudy in Association With RO7496353 Study GO44010
Not yet reported Genentech, Inc. 102 participants Est. completion 2026-03-16 27 sites Stand-aloneOther conditions: Non-small Cell Lung Cancer, Gastric Cancer, Pancreatic Ductal AdenocarcinomaView official trial listing → -
Active, not recruiting NCT NCT05878691
A Study of GRC 54276 in Participants With Advanced Solid Tumors and Lymphomas.
Not yet reported Glenmark Specialty S.A. 320 participants Est. completion 2027-07-30 18 sites Stand-aloneOther conditions: Advanced Solid Tumor, LymphomaView official trial listing → -
Status unknown NCT NCT05879328
The ImmunoXXL Study
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano 12 participants Est. completion 2024-12-31 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Withdrawn NCT NCT05886257
Candonilimab Plus Bevacizumab for Patients With Advanced HCC Who Progressed on A+T
Not yet reported Shi Ming Est. completion 2023-03-31 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT05886465
HAIC Plus A+T for Patients With High-risk HCC: a Single-arm Phase 2 Trial
Not yet reported Sun Yat-sen University 40 participants Est. completion 2024-12-01 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT05904886
A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in Participants With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) (IMbrave152)
Not yet reported Hoffmann-La Roche 687 participants Est. completion 2026-09-01 171 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT05908786
A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma
Not yet reported, Not yet reported Hoffmann-La Roche 62 participants Est. completion 2025-11-13 14 sites Stand-aloneOther conditions: Carcinoma, HepatocellularView official trial listing → -
Status unknown NCT NCT05908916
Atezolizumab and Bevacizumab With Combined Radiotherapy for Advanced Hepatocellular Carcinoma
Not yet reported Yonsei University 51 participants Est. completion 2026-07 1 site Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT05934214
EXploring Immune-related Adverse Events of Immune checkpoinT Inhibitors Using VigiBase, the WHO Pharmacovigilance Database
Groupe Hospitalier Pitie-Salpetriere 141630 participants Est. completion 2024-02-29 2 sitesOther conditions: Cancer, Immune-related Adverse Event, Immune Checkpoint Inhibitor-Related MyocarditisView official trial listing → -
Withdrawn NCT NCT05935774
OT-101 in Combination With Atezolizumab for the Treatment of Metastatic or Recurrent Non-Small Cell Lung Cancer
Not yet reported University of Washington Est. completion 2028-07-31 1 site Stand-aloneOther conditions: Metastatic Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8View official trial listing → -
Active, not recruiting NCT NCT05968326
A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC
Not yet reported Genentech, Inc. 260 participants Est. completion 2031-01-01 87 sites Stand-aloneOther conditions: Adenocarcinoma, Pancreatic DuctalView official trial listing → -
Status unknown NCT NCT05991206
A Real-World Study of Atezolizumab in Combination With Platinum-Based Doublet Chemotherapy as Neoadjuvant Therapy for Resectable Stage II-IIIB NSCLC
Hunan Province Tumor Hospital 200 participants Est. completion 2026-08-01 1 siteOther conditions: NSCLCView official trial listing → -
Active, not recruiting NCT NCT05999812
Clinical Trial of All-trans-retinoic Acid, Bevacizumab and Atezolizumab in Colorectal Cancer
Not yet reported University of Texas Southwestern Medical Center 22 participants Est. completion 2028-10-01 1 site Stand-aloneOther conditions: Colorectal CancerView official trial listing → -
Withdrawn NCT NCT06006286
A Study Evaluating Atezolizumab and Bevacizumab Plus ADI-PEG 20 in Patients With Locally Advanced / Metastatic Hepatocellular Carcinoma
Not yet reported, Not yet reported M.D. Anderson Cancer Center Est. completion 2023-11-10 1 site Stand-aloneOther conditions: Metastatic Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT06024252
Efficacy, Safety, and Treatment Patterns of Transcatheter Arterial Chemoembolization (TACE) Combined With Atezolizumab and Bevacizumab in Unresectable Hepatocellular Carcinoma: a Multicenter, Retrospective, Observational Real-world Study
Zhongda Hospital 200 participants Est. completion 2024-06-01Other conditions: HCCView official trial listing → -
Active, not recruiting NCT NCT06031441
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
Not yet reported Genentech, Inc. 65 participants Est. completion 2027-03-03 18 sites Stand-aloneOther conditions: Locally Advanced Solid Tumors, Recurrent Solid Tumors, Metastatic Solid TumorsView official trial listing → -
Status unknown NCT NCT06031597
Radiotherapy Combined With ICIs as Treatment for LA-NSCLC After Failing Induction Immunochemotherapy
Not yet reported Zhejiang Cancer Hospital 105 participants Est. completion 2025-12-31Other conditions: Non-small Cell Lung Cancer Stage IIIView official trial listing → -
Completed NCT NCT06049966
Atezolizumab in Large Cell Neuroendocrine Carcinoma
Not yet reported Oncology Center of Biochemical Education And Research 22 participants Est. completion 2025-09-01 3 sites Stand-aloneOther conditions: Large Cell Neuroendocrine Carcinoma of the LungView official trial listing → -
Terminated NCT NCT06067061
"neoBREASTIM": Atezolizumab Plus RP1 Oncolytic Immunotherapy in the NeoAdjuvant Setting of Triple-Negative Breast Cancer
Not yet reported, Not yet reported Institut Curie 2 participants Est. completion 2025-05-07 1 site Stand-aloneOther conditions: Triple Negative Breast NeoplasmsView official trial listing → -
Active, not recruiting NCT NCT06077500
DAREONᵀᴹ-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer
Not yet reported Boehringer Ingelheim 46 participants Est. completion 2027-04-01 21 sites Stand-aloneOther conditions: Small Cell Lung Carcinoma (SCLC)View official trial listing → -
Withdrawn NCT NCT06090318
Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A Loss
Not yet reported, Not yet reported Rain Oncology Inc Est. completion 2023-05-30 Stand-aloneOther conditions: Advanced Solid Tumor, CDKN2A, NSCLC, Urothelial Carcinoma Bladder, Melanoma, Pancreas Adenocarcinoma, HNSCC, Renal Cell Carcinoma, Mesothelioma, Gastric CancerView official trial listing → -
Active, not recruiting NCT NCT06096779
A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis
Not yet reported Genentech, Inc. 30 participants Est. completion 2027-12-30 54 sites Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT06098898
Safety and Efficacy of NK510 to Treat Gastric Cancer
Not yet reported Base Therapeutics (Shanghai) Co., Ltd. 9 participants Est. completion 2024-11-01 1 site Stand-aloneOther conditions: Gastric CancerView official trial listing → -
Withdrawn NCT NCT06099418
Efficacy and Safety of VB10.16 Alone or in Combination With Atezolizumab in Patients With Advanced Cervical Cancer.
Not yet reported Nykode Therapeutics ASA Est. completion 2028-05 Stand-aloneOther conditions: HPV-Related Cervical Carcinoma, HPV-Related Malignancy, Cervical CancerView official trial listing → -
Active, not recruiting NCT NCT06109272
A Study to Assess the Dose, Adverse Events, and Change in Disease Activity of Livmoniplimab as an Intravenous (IV) Solution in Combination With Budigalimab as an IV Solution in Adult Participants With Hepatocellular Carcinoma (HCC)
Not yet reported, Not yet reported AbbVie 89 participants Est. completion 2027-01 37 sitesOther conditions: Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT06117891
An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery
Bayer 300 participants Est. completion 2026-12-10 17 sitesOther conditions: Unresectable Hepatocellular CarcinomaView official trial listing → -
Active, not recruiting NCT NCT06138769
Lenvatinib After Progression on Atezolizumab-bevacizumab in Hepatocellular Carcinoma
Not yet reported Asan Medical Center 50 participants Est. completion 2027-11-01 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT06169904
B7-Family Score in Urothelial Carcinoma
Shanghai Zhongshan Hospital 215 participants Est. completion 2022-11-22Other conditions: Urothelial CarcinomaView official trial listing → -
Active, not recruiting NCT NCT06175390
Tiragolumab, Atezolizumab and Chemotherapy in Triple Negative Breast Cancer
Not yet reported Institut Curie 81 participants Est. completion 2029-02-15 2 sites Stand-aloneOther conditions: Triple Negative Breast CancerView official trial listing → -
Status unknown NCT NCT06194695
DEB-TACE, Lenvatinib and Anti-PD(L)1 Antibody as Conversion Therapy for Intrahepatic Cholangiocarcinoma
Ze-yang Ding, MD 100 participants Est. completion 2025-06-30 1 siteOther conditions: Cholangiocarcinoma Non-resectableView official trial listing → -
Status unknown NCT NCT06195683
Serplulimab for Patients With Non-small Cell Lung Cancer (NSCLC) With TPS ≥ 50%: a Prospective, Single-center, Single-arm Phase 2 Study.
Not yet reported Zhejiang Cancer Hospital 23 participants Est. completion 2025-06-20 1 siteOther conditions: Non-small Cell Lung Cancer, PDL1 Gene MutationView official trial listing → -
Completed NCT NCT06199297
Atezolizumab Plus Bevacizumab Versus Sintilimab Plus Bevacizumab With TACE and HAIC in Unresectable Hepatocellular Carcinoma
Sun Yat-sen University 188 participants Est. completion 2023-07-25 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Status unknown NCT NCT06205732
A Retrospective Study on the Treatment of Intermediate and Advanced Liver Cancer.
Qianfoshan Hospital 100 participants Est. completion 2024-12 1 siteOther conditions: Carcinoma, HepatocellularView official trial listing → -
Status unknown NCT NCT06244446
Efficacy and Safety of SBRT Combined With Atezolizumab Plus Bevacizumab vs Atezolizumab Plus Bevacizumab in Treating Unresectable Advance Hepatocellular Carcinoma.
Institute of Liver and Biliary Sciences, India 40 participants Est. completion 2025-01-31 1 siteOther conditions: Advanced Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT06261138
Survival Analysis: TACE vs. Combination Therapy in HCC
Zhejiang University 279 participants Est. completion 2023-10-31 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT06267001
A Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based Chemotherapy
Not yet reported Hoffmann-La Roche 56 participants Est. completion 2025-12-16 37 sites Stand-aloneOther conditions: Non-small Cell Lung Cancer (NSCLC)View official trial listing → -
Withdrawn NCT NCT06328036
Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma
Not yet reported National Cancer Institute (NCI) Est. completion 2025-07-01 Stand-aloneOther conditions: Recurrent Glioblastoma, IDH-WildtypeView official trial listing → -
Withdrawn NCT NCT06331598
A Study of Adjuvant Atezolizumab or Atezolizumab Plus Tiragolumab in Solid Tumors with Resectable Disease with Intermediate-High Risk of Recurrence and High Tumor Mutational Burden (TMB-H) or Microsatellite Instability (MSI-H)
Not yet reported Hoffmann-La Roche Est. completion 2029-09-20 3 sites Stand-aloneOther conditions: Solid TumorsView official trial listing → -
Status unknown NCT NCT06356701
Tumor Nutritional Therapy in the First-line Treatment of Stage IV NSCLC
Not yet reported The First Affiliated Hospital of Dalian Medical University 120 participants Est. completion 2025-12-31 1 siteOther conditions: Long-Term Effects Secondary to Cancer TherapyView official trial listing → -
Completed NCT NCT06390059
EF-39 PANOVA-4: Study of Tumor Treating Fields Concomitant With Atezolizumab, Gemcitabine and Nab-Paclitaxel as First-LineTreatment for Metastatic Pancreatic Ductal Adenocarcinoma
Not yet reported NovoCure Ltd. 84 participants Est. completion 2025-11-18 15 sites Stand-aloneOther conditions: Metastatic Pancreatic Ductal AdenocarcinomaView official trial listing → -
Withdrawn NCT NCT06416436
Dose-escalation Study of Ultra-high Dose Ablative Radiosurgery With Immunotherapy for Bulky Metastatic Cancer Patients
Not yet reported University of Kansas Medical Center Est. completion 2024-07-15 1 site Stand-aloneOther conditions: Solid TumorView official trial listing → -
Completed NCT NCT06416683
Atezolizumab and Bevacizumab Combination Recommended in a Multidisciplinary Consultation Meeting in Caen for Hepatocellular Carcinoma (ABCHCaen)
University Hospital, Caen 109 participants Est. completion 2024-01-30 1 siteOther conditions: Atezolizumab and Bevacizumab in Hepatocellular CarcinomaView official trial listing → -
Terminated NCT NCT06488716
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7759065 as a Single Agent and in Combination With Atezolizumab in Patients With Locally Advanced or Metastatic Solid Tumors
Not yet reported Genentech, Inc. 12 participants Est. completion 2025-11-05 11 sites Stand-aloneOther conditions: Solid TumourView official trial listing → -
Active, not recruiting NCT NCT06496568
A Study Evaluating Single-agent Inavolisib, Inavolisib Plus Atezolizumab in PIK3CA-Mutated Cancers
Not yet reported Hoffmann-La Roche 30 participants Est. completion 2027-07-21 5 sites Stand-aloneOther conditions: PIK3CA-Mutated CancersView official trial listing → -
Completed NCT NCT06503250
A Study of Participants With Initially Unresectable Hepatocellular Carcinoma That is Treated With Atezolizumab and Bevacizumab Plus Transarterial Chemoembolization
Hoffmann-La Roche 113 participants Est. completion 2024-11-27 5 sitesOther conditions: Unresectable Hepatocellular CarcinomaView official trial listing → -
Not yet recruiting NCT NCT06535737
A Phase 2, Single Arm Study of Cabozantinib in Patients With Hepatocellular Carcinoma Who Have Received Prior Atezolizumab and Bevacizumab
Not yet reported Chulalongkorn University 40 participants Est. completion 2026-12Other conditions: Hepatocellular Carcinoma Non-resectableView official trial listing → -
Active, not recruiting NCT NCT06537310
A Dose-escalation Study of RO7567132 as Single Agent and in Combination With Atezolizumab in Participants With Advanced Solid Tumors
Not yet reported Hoffmann-La Roche 34 participants Est. completion 2027-08-10 11 sites Stand-aloneOther conditions: Cancer-NeoplasmsView official trial listing → -
Withdrawn NCT NCT06557278
Combined AlloStim+Anti-PD-L1 in 4L MSS Metastatic Colorectal Cancer
Not yet reported Mirror Biologics, Inc. Est. completion 2028-11 3 sitesOther conditions: Metastatic Colorectal CancerView official trial listing → -
Status unknown NCT NCT06558903
Searching for Predictive Biomarkers of Efficacy in Small Cell Lung Cancer Patients Treated With Chemotherapy-immunotherapy Combination Using Imaging Mass Cytometry (HYPE)
University Hospital, Brest 20 participants Est. completion 2025-01-01 1 siteOther conditions: Small Cell Lung CarcinomaView official trial listing → -
Withdrawn NCT NCT06572722
Perioperative Immunotherapy for NSCLC (ECTOP-1030)
Not yet reported Fudan University Est. completion 2029-09-01 Stand-aloneOther conditions: Lung CancerView official trial listing → -
Not yet recruiting NCT NCT06584071
A Study to Evaluate of PM8002 Combined With PM1009 in Patients With First-line HCC
Not yet reported, Not yet reported Biotheus Inc. 140 participants Est. completion 2027-12Other conditions: HCC, Liver CancerView official trial listing → -
Not yet recruiting NCT NCT06592612
Second-line Systemic Therapy Combined with SBRT for HCC with Oligoprogression After Standard First-line Systemic Treatment
Not yet reported Sun Yat-sen University 70 participants Est. completion 2026-10-31Other conditions: Hepatocellular Carcinoma, OligoprogressionView official trial listing → -
Withdrawn NCT NCT06603818
Immunotherapies in Combination With Stereotactic Body Radiation Radiotherapy in Microsatellite Stable (MSS) Metastatic Colorectal Cancer (mCRC)
Not yet reported National Cancer Institute (NCI) Est. completion 2025-08-15 1 site Stand-aloneObstructive sleep apnea Other conditions: Metastatic Colorectal Cancer, Colorectal CancerView official trial listing → -
Suspended NCT NCT06616623
Vismodegib and Atezolizumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer
Not yet reported Dwight Owen 24 participants Est. completion 2027-12-01 1 site Stand-aloneOther conditions: Metastatic Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8View official trial listing → -
Active, not recruiting NCT NCT06632106
HAIC in Combination with Immune Checkpoint Inhibitors and Tyrosine Kinase Inhibitors for Advanced HCC
First Hospital of China Medical University 97 participants Est. completion 2025-05-30 1 siteOther conditions: Hepatic Arterial Infusion Chemotherapy, Tyrosine Kinase Inhibitor, Immune Checkpoint Inhibitors, Hepatocellular Carcinoma (HCC)View official trial listing → -
Active, not recruiting NCT NCT06632327
Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer
Not yet reported Alliance for Clinical Trials in Oncology 37 participants Est. completion 2030-04-30 415 sites Stand-aloneOther conditions: Resectable Lung Non-Small Cell Carcinoma, Stage II Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8View official trial listing → -
Not yet recruiting NCT NCT06680258
A Study of TPST-1120 With Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic HCC Not Previously Treated With Systemic Therapy
Not yet reported Tempest Therapeutics 740 participants Est. completion 2030-07 Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Not yet recruiting NCT NCT06692491
Study of Precision Treatment for Rare Tumours in China Guided by PDO and NGS
Not yet reported Peking University Shenzhen Hospital 200 participants Est. completion 2029-12-31 Stand-aloneOther conditions: Rare TumourView official trial listing → -
Active, not recruiting NCT NCT06710223
Cryoablation and Arterial Infusion of SD-101 in Combination With Durvalumab and Tremelimumab
Not yet reported University of California, San Diego 16 participants Est. completion 2027-12 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Withdrawn NCT NCT06713798
Targeting PD-L1 and TIGIT in Tumors With Tertiary Lymphoid Structures
Not yet reported Gustave Roussy, Cancer Campus, Grand Paris Est. completion 2025-09-15 Stand-aloneOther conditions: Metastatic Cancer Lung, Advanced Lung Cancer, CBNPC CancerView official trial listing → -
Not yet recruiting NCT NCT06719336
Addition of Thoracic Consolidation Radiotherapy to the Maintenance Immunotherapy for ES-SCLC (STONE-001)
Not yet reported Anhui Shi, MD 182 participants Est. completion 2028-12-16 Stand-aloneOther conditions: Extensive-stage Small Cell Lung CancerView official trial listing → -
Withdrawn NCT NCT06719973
Phase 1 Study of M9466 Combined With Carboplatin and Platinum-based Anticancer Therapy (DDRiver 521)
Not yet reported EMD Serono Research & Development Institute, Inc. Est. completion 2025-05-14 Stand-aloneOther conditions: Advanced Solid TumorsView official trial listing → -
Terminated NCT NCT06739252
Perioperative Treatment of High-risk Resectable CCA With HAIC Plus A+T: Neobrave CCA
Not yet reported Peking University 1 participants Est. completion 2025-12-22 1 site Stand-aloneOther conditions: Intrahepatic Cholangiocarcinoma (Icc), Perihilar CholangiocarcinomaView official trial listing → -
Active, not recruiting NCT NCT06754501
A Phase 2 Clinical Trial Evaluating the Efficacy and Safety of Dual Immune Checkpoint Inhibition With Anti-PD-L1 (Atezolizumab) and Anti-TIGIT (Tiragolumab) in Cancer of Unknown Primary
Not yet reported M.D. Anderson Cancer Center 4 participants Est. completion 2029-07-01 1 site Stand-aloneOther conditions: CancerView official trial listing → -
Active, not recruiting NCT NCT06760481
Phase I/Ib Trial of TIraGolumab, AtEzolizumab, and RadScopal Radiation in Patients With Advanced Solid Malignancies (TIGER)
Not yet reported M.D. Anderson Cancer Center 7 participants Est. completion 2030-09-15 1 site Stand-aloneOther conditions: Advanced Solid MalignanciesView official trial listing → -
Withdrawn NCT NCT06762808
Phase II Study of Atezolizumab and Tiragolumab With ctDNA for HPV-positive SCC
Not yet reported M.D. Anderson Cancer Center Est. completion 2025-08-08 Stand-aloneOther conditions: Squamous Cell CarcinomaView official trial listing → -
Active, not recruiting NCT NCT06771622
Safety and Efficacy of HCB101 in Combination With Multiple Agents in Patients With Advanced Solid Tumors
Not yet reported, Not yet reported FBD Biologics Limited 500 participants Est. completion 2029-01-01 1 site Stand-aloneOther conditions: Solid CancerView official trial listing → -
Active, not recruiting NCT NCT06784947
Trial of Atezolizumab, Bevacizumab, and Tiragolumab in Patients With Microsatellite Stable, Metastatic Colorectal Cancer
Not yet reported University of Colorado, Denver 13 participants Est. completion 2028-05 1 site Stand-aloneObstructive sleep apnea Other conditions: Metastatic Colorectal Cancer (CRC), Colorectal Cancer Stage IVView official trial listing → -
Not yet recruiting NCT NCT06867432
Efficacy and Safety of Yttrium-90 Microspheres Selective Internal Radiotherapy Combined with Immune Checkpoint Inhibitors and Anti-angiogenesis Drugs Sequential HAIC for Hepatocellular Carcinoma
Not yet reported Tianjin Medical University Cancer Institute and Hospital 20 participants Est. completion 2027-03-01 Stand-aloneOther conditions: Hepatocellular CarcinomaView official trial listing → -
Not yet recruiting NCT NCT06903663
The Epidemiology of Patients Treated With ATZ+BEV in Real Life Setting
Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor 100 participants Est. completion 2025-12 4 sitesOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Terminated NCT NCT06939036
Study of 225Ac-SS0110 in Subjects With ES-SCLC or MCC (SANTANA-225 )
Not yet reported, Not yet reported Ariceum Therapeutics GmbH 2 participants Est. completion 2025-12-31 7 sites Stand-aloneOther conditions: Small Cell Lung Cancer Extensive Stage, Merkel Cell CarcinomaView official trial listing → -
Not yet recruiting NCT NCT06971237
SIRT and Peri-immunotherapy : a New Concept
Assistance Publique - Hôpitaux de Paris 60 participants Est. completion 2026-07-01 1 siteOther conditions: Advanced Hepatocellular Carcinoma (HCC), Classified as BCLC Stage B or C, Treated With a Combination of Selective Internal Radiation TherapyView official trial listing → -
Not yet recruiting NCT NCT06984718
A Phase II Study of AK104 Combination With Lenvatinib Versus Lenvatinib for Second-line HCC
Not yet reported Akeso 120 participants Est. completion 2027-06-30Other conditions: HCC, Hepatocellular CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07035860
Efficacy and Safety of Chemoimmunotherapy and Carbon Ion Radiotherapy in Unresectable Locally Advanced Non-small Cell Lung Cancer
Ji Yongling 34 participants Est. completion 2028-06-15 1 siteOther conditions: Carbon Ion RadiotherayView official trial listing → -
Completed NCT NCT07036016
Interstitial Pneumonitis Associated With EGFR-TKI and Combined With PD-1/PD-L1
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 67818 participants Est. completion 2025-05-01Other conditions: Non-Small Cell Lung Cancer (NSCLC)View official trial listing → -
Not yet recruiting NCT NCT07045558
HAIC + Atezolizumab Plus Bevacizumab in Unresectable HCC
RenJi Hospital 28 participants Est. completion 2028-01-31 1 siteOther conditions: Unresectable Hepatocellular CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07051928
Study of Atezolizumab in Advanced Non-oncogene-addicted NSCLC With PD-L1 ≥50%, Including Longitudinal c-FLIP Assessment in Monocytic MDSCs.
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 107 participants Est. completion 2029-07 1 siteOther conditions: Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT07091942
Curative Therapy After Atezolizumab and Bevacizumab Treatment for Unresectable Hepatocellular Carcinoma
National Taiwan University Hospital 243 participants Est. completion 2026-10-08 1 siteOther conditions: Hepatocellular CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07093762
Efficacy and Safety Analysis of First-Line ABCP Therapy in Advanced SMARCA4-Mutated NSCLC
Fuzhou General Hospital 35 participants Est. completion 2028-06-30 1 siteOther conditions: Non Small Cell Lung CancerView official trial listing → -
Completed NCT NCT07109336
Development and Prospective Validation of a Heterogeneous Treatment Effect-Based Decision Model for Transarterial Chemoembolization Combined With or Without Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma
Not yet reported Zhongda Hospital 236 participants Est. completion 2026-08-30 1 siteOther conditions: HCC - Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT07111104
Survival Efficacy of Combined Radiotherapy and Immunotherapy in Patients With Metastatic Non-small Cell Lung Carcinoma
Hopitaux Prives de Metz, Groupe UNEOS 350 participants Est. completion 2025-04-28 1 siteOther conditions: Non Small Cell Lung Cancer MetastaticView official trial listing → -
Not yet recruiting NCT NCT07168668
Partial Immune-boost TACE in unrEseCTable HCC Patients Under Systemic Treatment
Not yet reported Chang Gung Memorial Hospital 90 participants Est. completion 2029-08-14Other conditions: HCC, Tace, ImmunotherapyView official trial listing → -
Not yet recruiting NCT NCT07170592
A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients
Not yet reported Bionoxx Inc. 24 participants Est. completion 2030-12 Stand-aloneOther conditions: Treatment-Refractory Solid TumorsView official trial listing → -
Not yet recruiting NCT NCT07172412
Open-Label, Biomarker-Integrated Umbrella Trial for First-Line Treatment of Extensive-stage Small Cell Lung Cancer
Not yet reported Tianjin Medical University Cancer Institute and Hospital 165 participants Est. completion 2028-12 1 site Stand-aloneOther conditions: Extensive Stage Lung Small Cell CancerView official trial listing → -
Not yet recruiting NCT NCT07190027
Immunodynamics-Guided Optimization of Individualized Immunochemotherapy in Advanced Driver-Negative NSCLC: A Randomized Trial
Not yet reported, Not yet reported First Affiliated Hospital of Wenzhou Medical University 246 participants Est. completion 2028-11 Stand-aloneOther conditions: Advanced Non-Small Cell Lung Cancer (NSCLC)View official trial listing → -
Completed NCT NCT07192926
Body Composition and Inflammatory-Metabolic Indices in Immunotherapy-Treated Metastatic Non-Small Cell Lung Cancer: The SARC-CTI Study
Ankara Etlik City Hospital 155 participants Est. completion 2026-06-11 2 sitesOther conditions: Metastatic Non-small Cell Lung Cancer, NeoplasmView official trial listing → -
Completed NCT NCT07193316
Safety and Efficacy of Atezolizumab-Bevacizumab Versus Tyrosin Kinase Inhibitors in Patients With Liver Cirrhosis
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 38 participants Est. completion 2025-09-25 1 siteOther conditions: Hepatocellular Carcinoma, Liver CirrhosisView official trial listing → -
Active, not recruiting NCT NCT07204327
Atezolizumab Plus Bevacizumab Combined With Locoregional Therapies in Unresectable Hepatocellular Carcinoma (ISMIO-001)
Zhongda Hospital 1136 participants Est. completion 2026-12-31 1 siteOther conditions: Unresectable Hepatocellular CarcinomaView official trial listing → -
Completed NCT NCT07272265
The Effectiveness and Safety in High-risk Patients Receiving First-line Atezolizumab and Bevacizumab Combined With HAIC for HCC: a Retrospective Study
Not yet reported Sun Yat-sen University 300 participants Est. completion 2025-11-10 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Active, not recruiting NCT NCT07280377
A Study in Advanced or Metastatic Gastrointestinal Cancers Exploring Treatment Combinations With Pelareorep and Atezolizumab
Not yet reported, Not yet reported Oncolytics Biotech 122 participants Est. completion 2028-12-31 15 sites Stand-aloneOther conditions: Anal Cancer Metastatic, Squamous Cell Carcinoma of the Anus Stage Unspecified, Pancreatic Cancer Metastatic, Unresectable Pancreatic CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07281664
Transarterial Chemoembolization With Low-Dose Bevacizumab Plus Atezolizumab as First-Line Treatment for Unresectable Hepatocellular Carcinoma
Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 30 participants Est. completion 2029-12-31 Stand-aloneOther conditions: Hepatocellular Carcinoma, Transarterial ChemoembolizationView official trial listing → -
Not yet recruiting NCT NCT07351513
A Phase II Trial of Organoid Drug Sensitivity Testing to Guide Therapy in Unresectable Hepatocellular Carcinoma
Not yet reported Eastern Hepatobiliary Surgery Hospital 94 participants Est. completion 2028-12-31 Stand-aloneOther conditions: Unresectable Hepatocellular CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07363356
Drug Sensitivity Testing-Based Tumor Organoids to Guide Adjuvant Therapy After Hepatectomy for Primary Liver Cancer
Not yet reported Eastern Hepatobiliary Surgery Hospital 56 participants Est. completion 2028-11-30 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma ResectableView official trial listing → -
Not yet recruiting NCT NCT07461675
Effects of Neoadjuvant Immunotherapy on Anti-tumour Immunity in Hepatocellular Carcinoma Patients Undergoing Liver Resection
Not yet reported University of Geneva, Switzerland 30 participants Est. completion 2029-12-31 1 site Stand-aloneOther conditions: Hepato Cellular Carcinoma (HCC), ImmunotherapyView official trial listing → -
Not yet recruiting NCT NCT07543510
Low-Dose Bevacizumab and Atezolizumab Combined With TACE-HAIC in Unresectable Hepatocellular Carcinoma
Not yet reported Third Affiliated Hospital, Sun Yat-Sen University 38 participants Est. completion 2029-08-31 Stand-aloneOther conditions: Hepatocellular Carcinoma, Atezolizumab Plus Bevacizumab, Transarterial ChemoembolizationView official trial listing → -
Enrolling by invitation NCT NCT07620574
Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study
Not yet reported Exelixis 5000 participants Est. completion 2030-05-31 2 sites Stand-aloneOther conditions: Cancer, Renal Cell Carcinoma (RCC), Pancreatic Neuroendocrine Tumors (pNET), Extra-Pancreatic NET (epNET), Hepatocellular Carcinoma (HCC), Differentiated Thyroid Cancer (DTC), Non-Clear Cell Renal Cell Carcinoma (nccRCC), Colorectal Cancer, Prostate CancerView official trial listing → -
Completed NCT NCT07639294
The Application of Locoregional Therapy Combined With Systemic Therapy in the Perioperative Period of Huge Hepatocellular Carcinoma: A Retrospective Cohort Study
Tongji Hospital 715 participants Est. completion 2025-12-31 1 siteOther conditions: Huge Hepatocellular Carcinoma (HCC) (>10cm)View official trial listing → -
Active, not recruiting NCT NCT07645209
A Real-world Study of Immunotherapy Combination Regimens for Treating Liver Cancer in Cold Regions
Harbin Medical University 1000 participants Est. completion 2029-05-13 1 siteOther conditions: Liver CancerView official trial listing → -
Not yet recruiting NCT NCT07661251
ITTACA (Immunotherapy Time Teller for Advanced Lung Cancer)
Laura Longshaw 60 participants Est. completion 2028-04Other conditions: Non-Small Cell Lung CancerView official trial listing → -
Active, not recruiting NCT NCT07669597
Comparison of Atezolizumab/Bevacizumab Versus Durvalumab/Tremelimumab (STRIDE) Protocols in Locally Advanced or Metastatic Hepatocellular Carcinoma Among Patients in Sohag
Sohag Oncology Center 50 participants Est. completion 2027-06-01 1 siteOther conditions: Locally Advanced or Metastatic Hepatoceullar CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07707895
DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine Cancers
Not yet reported, Not yet reported Boehringer Ingelheim 60 participants Est. completion 2030-04-26 27 sites Stand-aloneOther conditions: Small Cell Lung Cancer, Large Cell Neuroendocrine Lung Carcinoma, Extrapulmonary Neuroendocrine Carcinoma of Small Cell Histology, Extrapulmonary Neuroendocrine Carcinoma of Large Cell HistologyView official trial listing → -
Not yet recruiting NCT NCT07734857
Peripheral Blood Biomarkers and Response to Atezolizumab Plus Bevacizumab in Hepatocellular Carcinoma
Shanghai Zhongshan Hospital 100 participants Est. completion 2028-07-30Other conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Not yet recruiting NCT NCT07774247
Atezolizumab, Bevacizumab, and Tocilizumab in Advanced Hepatocellular Carcinoma
Not yet reported CHA University 51 participants Est. completion 2029-09-01 1 site Stand-aloneOther conditions: Hepatocellular Carcinoma (HCC)View official trial listing → -
Not yet recruiting NCT NCT07786792
Biomarker and Mechanism Study of Systemic Therapy in Unresectable HCC
Shanghai Zhongshan Hospital 400 participants Est. completion 2027-01-01Other conditions: Hepatocellular CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07796100
A Study of ZL-1310 in Combination With a Checkpoint Inhibitor Versus Standard of Care Platinum Based Chemotherapy With a Checkpoint Inhibitor as First-line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer
Not yet reported Zai Lab (Shanghai) Co., Ltd. 530 participants Est. completion 2031-06-30 Stand-aloneOther conditions: Extensive-Stage Small Cell Lung CancerView official trial listing → -
Not yet recruiting NCT NCT07824765
Heterogeneity of Treatment Effects of Adding Locoregional Therapies to Atezolizumab Plus Bevacizumab in Patients With Unresectable Hepatocellular Carcinoma (ISMIO-026)
Zhongda Hospital 2658 participants Est. completion 2027-12-31 1 siteOther conditions: Unresectable Hepatocellular CarcinomaView official trial listing → -
Not yet recruiting NCT NCT07835737
Safety and Efficacy of Folic Acid Combined With Atezolizumab and Bevacizumab as First-Line Therapy for Unresectable Hepatocellular Carcinoma
Not yet reported, Not yet reported West China Hospital 78 participants Est. completion 2029-10-01 Stand-aloneOther conditions: Unresectable Hepatocellular CarcinomaView official trial listing →
Efficacy history
Not yet reported.
Safety
Not yet reported.
Sources
Also known as: Atezolizumab, TECENTRIQ, MPDL 3280A, MPDL 328OA, RG 7446, RO 5541267
Related On The Pen coverage
No related coverage yet.
This drug may be investigational and not yet approved for any use. Whether someone can join a clinical trial is determined only by that trial's own study team — On The Pen does not determine eligibility. Information here can change; always confirm current details on the official ClinicalTrials.gov listing or with the sponsor.
