About this data Sourced primarily from ClinicalTrials.gov — a listing isn't proof of safety or FDA approval.

Pipeline and clinical trial information here comes primarily from ClinicalTrials.gov. A listing on ClinicalTrials.gov means a study has been registered — not that a treatment is proven safe, effective, or FDA-approved. Investigational treatments may never be approved. Who can join a trial is decided only by that trial's own study team.

Not yet reported

Allopurinol

Company: Crystalys Therapeutics
Mechanism: Mechanism not yet reported
Route: Route not yet reported
Recruiting trials: 15 recruiting

Efficacy results: Not yet reported

Find a Clinical Trial Near Me

15 recruiting studies currently listed on ClinicalTrials.gov.

Data source: ClinicalTrials.gov · trial data as of Sep 29, 2026

Trial details

Recruiting NCT NCT03150693

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

Not yet reported Alliance for Clinical Trials in Oncology 303 participants Est. completion 2027-08 460 sites Stand-alone

Other conditions: B Acute Lymphoblastic Leukemia
View official trial listing →
Recruiting NCT NCT04026776

Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm

Not yet reported Wake Forest University Health Sciences 120 participants Est. completion 2026-12 1 site Stand-alone

Other conditions: Salt; Excess, Blood Pressure Disorders
View official trial listing →
Recruiting NCT NCT04217421

Cerebrum and Cardiac Protection With Allopurinol in Neonates With Critical Congenital Heart Disease Requiring Cardiac Surgery With Cardiopulmonary Bypass

Not yet reported dr. M.J.N.L. Benders 236 participants Est. completion 2028-12-31 4 sites

Other conditions: Congenital Heart Disease in Children, Neuroprotection
View official trial listing →
Recruiting NCT NCT04875702

Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout

Not yet reported Massachusetts General Hospital 650 participants Est. completion 2028-10-31 7 sites

Other conditions: Gout
View official trial listing →
Recruiting NCT NCT05536349

Time-limited Triplet Combination of Pirtobrutinib, Venetoclax, and Obinutuzumab for Patients With Treatment-naïve Chronic Lymphocytic Leukemia (CLL) or Richter Transformation (RT)

Not yet reported M.D. Anderson Cancer Center 60 participants Est. completion 2028-04-25 1 site Stand-alone

Other conditions: Leukemia
View official trial listing →
Recruiting NCT NCT05805605

Allo HSCT Using RIC and PTCy for Hematological Diseases

Not yet reported Masonic Cancer Center, University of Minnesota 56 participants Est. completion 2028-10-22 1 site Stand-alone

Other conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Biphenotypic Acute Leukemia, Undifferentiated Leukemia, Prolymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Leukemia, Myeloid, Myelodysplastic Syndrome With Excess Blasts-1, Burkitt Lymphoma, Relapsed T-Cell Lymphoma, Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone Lymphoma, Follicular Lymphoma, Myeloproliferative Neoplasm, Myelofibrosis
View official trial listing →
Recruiting NCT NCT05943821

The Effect of Allopurinol on the Risk of Cardiovascular Events in Patients with Cardiovascular Risk

Not yet reported Poznan University of Medical Sciences 1116 participants Est. completion 2028-07-31 1 site

Cardiovascular disease Other conditions: Uric Acid
View official trial listing →
Recruiting NCT NCT06622603

the Effects of Febuxostat Dose Tapering in Gout Patients Optimally Controlled for 5 Years or More

Not yet reported Seoul National University Hospital 59 participants Est. completion 2027-08-19 1 site

Other conditions: Gout, Uric Acid
View official trial listing →
Recruiting NCT NCT06669000

Time Required to Dissolve Urate Deposits

Assistance Publique - Hôpitaux de Paris 250 participants Est. completion 2032-09-24 1 site

Other conditions: Gout
View official trial listing →
Recruiting NCT NCT06966635

Exploratory Study on the Treatment of Gout With Potassium Citrate Sustained-release Tablets

Not yet reported Huashan Hospital 312 participants Est. completion 2026-04-30 1 site Stand-alone

Other conditions: Hyperuricemia or Gout, Nephrolithiasis
View official trial listing →
Recruiting NCT NCT07089875

A Study of Dotinurad Versus Allopurinol in Participants With Gout

Not yet reported Crystalys Therapeutics 500 participants Est. completion 2027-11-29 115 sites Stand-alone

Other conditions: Gout
View official trial listing →
Recruiting NCT NCT07089888

A Study of Dotinurad Versus Allopurinol in Tophaceous Gout

Not yet reported Crystalys Therapeutics 250 participants Est. completion 2027-12-31 95 sites Stand-alone

Other conditions: Tophaceous Gout
View official trial listing →
Recruiting NCT NCT07367971

Drug-Drug Interaction Study of ABP-671 in Gout Patients

Not yet reported Atom Therapeutics Co., Ltd 20 participants Est. completion 2026-08-31 1 site Stand-alone

Other conditions: Gout Chronic, Gout, DDI (Drug-Drug Interaction)
View official trial listing →
Recruiting NCT NCT07574060

Allopurinol in Depression

Not yet reported, Not yet reported Tanta University 70 participants Est. completion 2027-05-20 1 site

Other conditions: Depression
View official trial listing →
Recruiting NCT NCT07800598

Role of Allopurinol in Prevention of Complications Related to Decompensated Cirrhosis of Liver

Not yet reported Bangladesh Medical University 54 participants Est. completion 2027-07 2 sites

Other conditions: Cirrhoses, Liver, Decompensated Cirrhosis of Liver
View official trial listing →
Completed NCT NCT00000658

A Phase III Randomized Trial of Low-Dose Versus Standard-Dose mBACOD Chemotherapy With rGM-CSF for Treatment of AIDS-Associated Non-Hodgkin's Lymphoma

Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 250 participants Est. completion 1996-02 22 sites

Other conditions: Lymphoma, Non-Hodgkin, HIV Infections
View official trial listing →
Completed NCT NCT00000703

Chemotherapy and Azidothymidine, With or Without Radiotherapy, for High Grade Lymphoma in AIDS-Risk Group Members

Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 45 participants Est. completion 1990-03 14 sites

Other conditions: Lymphoma, Non-Hodgkin, HIV Infections
View official trial listing →
Completed NCT NCT00002571

SWOG-9320 Combination Chemotherapy, Radiation Therapy, and Antiviral Therapy in Treating Patients With AIDS-Related Lymphoma

Not yet reported SWOG Cancer Research Network 52 participants Est. completion 2011-07 85 sites Stand-alone

Other conditions: Lymphoma
View official trial listing →
Completed NCT NCT00003700

Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia

Not yet reported Alliance for Clinical Trials in Oncology 163 participants Est. completion 2010-01 50 sites Stand-alone

Other conditions: Leukemia
View official trial listing →
Completed NCT NCT00004755

Allopurinol, Glucantime, or Allopurinol/Glucantime for Cutaneous Leishmaniasis in Brazil

Not yet reported National Institute of Allergy and Infectious Diseases (NIAID) 375 participants

Other conditions: Leishmaniasis
View official trial listing →
Completed NCT NCT00039130

Rituximab, Chemotherapy, and Filgrastim in Treating Patients With Burkitt's Lymphoma or Burkitt's Leukemia

Not yet reported Alliance for Clinical Trials in Oncology 105 participants Est. completion 2014-10 31 sites Stand-alone

Other conditions: Leukemia, Lymphoma
View official trial listing →
Completed NCT NCT00053196

Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Cancer

Not yet reported Alliance for Clinical Trials in Oncology 82 participants Est. completion 2010-08 12 sites Stand-alone

Other conditions: Leukemia, Lymphoma, Multiple Myeloma, Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myeloproliferative Neoplasms
View official trial listing →
Completed NCT NCT00061945

Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia

Not yet reported, Not yet reported National Cancer Institute (NCI) 302 participants Est. completion 2012-10 1 site Stand-alone

Other conditions: Acute Undifferentiated Leukemia, B-cell Adult Acute Lymphoblastic Leukemia, B-cell Childhood Acute Lymphoblastic Leukemia, L1 Adult Acute Lymphoblastic Leukemia, L1 Childhood Acute Lymphoblastic Leukemia, L2 Adult Acute Lymphoblastic Leukemia, L2 Childhood Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia, Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia, Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia, T-cell Adult Acute Lymphoblastic Leukemia, T-cell Childhood Acute Lymphoblastic Leukemia, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Childhood Acute Lymphoblastic Leukemia
View official trial listing →
Completed NCT NCT00102440

Febuxostat Versus Allopurinol Control Trial in Subjects With Gout

Not yet reported Takeda 760 participants Est. completion 2004-02

Other conditions: Gout
View official trial listing →
Completed NCT NCT00109837

S0333 Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Not yet reported SWOG Cancer Research Network 79 participants Est. completion 2014-11 78 sites Stand-alone

Other conditions: Leukemia
View official trial listing →
Completed NCT NCT00111657

Pegylated Recombinant Mammalian Uricase (PEG-uricase) as Treatment for Refractory Gout

Not yet reported John Sundy 30 participants Est. completion 2009-07 1 site

Other conditions: Gout
View official trial listing →
Completed NCT NCT00116207

An Intervention Trial for Cardiac Neuropathy in Type 1 Diabetes

Not yet reported University of Michigan 44 participants Est. completion 2009-12 1 site Stand-alone

Other conditions: Diabetic Autonomic Neuropathy
View official trial listing →
Completed NCT NCT00174915

Phase 3, Febuxostat, Allopurinol and Placebo-Controlled Study in Gout Subjects.

Not yet reported Takeda 1072 participants Est. completion 2004-04

Other conditions: Gout
View official trial listing →
Completed NCT NCT00175019

Allopurinol Versus Febuxostat in Subjects Completing the Phase 3 Trials C02-009 or C02-010

Not yet reported Takeda 1086 participants Est. completion 2007-02

Other conditions: Gout
View official trial listing →
Completed NCT NCT00181155

Intravenous Allopurinol in Heart Failure

Not yet reported Johns Hopkins University 18 participants Est. completion 2010-12 1 site Stand-alone

Heart failure
View official trial listing →
Status unknown NCT NCT00189007

Antenatal Allopurinol During Fetal Hypoxia

Not yet reported UMC Utrecht 222 participants Est. completion 2016-12 11 sites Stand-alone

Other conditions: Fetal Hypoxia, Reperfusion Injury
View official trial listing →
Completed NCT NCT00199043

Treatment of Hyperuricemia With Rasburicase in Patients With Acute Lymphoblastic Leukemia or High Grade Lymphoma

Not yet reported Goethe University 80 participants Est. completion 2008-05 1 site Stand-alone

Other conditions: Adult Acute Lymphocytic Leukemia, High-grade Lymphoma
View official trial listing →
Withdrawn NCT NCT00214084

Vascular Pathophysiology in Obstructive Sleep Apnea

Not yet reported University of Wisconsin, Madison 1 site

Obstructive sleep apnea
View official trial listing →
Completed NCT NCT00230178

Rasburicase Versus Allopurinol in Tumor Patients at Risk for Hyperuricemia and Tumor Lysis Syndrome

Not yet reported Sanofi 280 participants Est. completion 2007-12 15 sites Stand-alone

Other conditions: Tumor Lysis Syndrome, Cancer, Hyperuricemia
View official trial listing →
Completed NCT NCT00241839

Uric Acid and Hypertension in African Americans

Not yet reported University of Florida 150 participants Est. completion 2011-05 1 site

Cardiovascular disease Other conditions: Heart Diseases, Hypertension
View official trial listing →
Completed NCT NCT00276003

INST Phase II Trial of Gemcitabine and Irinotecan in Patients With Relapsed or Refractory Lymphoma.

Not yet reported University of New Mexico 22 participants Est. completion 2005-08 2 sites

Other conditions: Non-Hodgkin's Lymphoma, Cancer
View official trial listing →
Withdrawn NCT NCT00281255

Intravenous Allopurinol to Improve Heart Function in Individuals With Dilated Cardiomyopathy

Not yet reported, Not yet reported University of Pennsylvania Est. completion 2013-06 1 site Stand-alone

Cardiovascular diseaseHeart failure Other conditions: Cardiomyopathy, Dilated, Heart Diseases
View official trial listing →
Terminated NCT NCT00281879

Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer

Not yet reported OHSU Knight Cancer Institute 200 participants Est. completion 2008-03 1 site

Other conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms, Unusual Cancers of Childhood
View official trial listing →
Completed NCT NCT00288158

Primary Prevention of Hypertension in Obese Adolescents

Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 60 participants Est. completion 2011-01 1 site Stand-alone

Other conditions: Obesity, Pre-Hypertension, Hyperuricemia
View official trial listing →
Withdrawn NCT NCT00288171

Allopurinol for Renal Transplant Associated Hypertension in Children

Not yet reported, Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Est. completion 2008-06 1 site Stand-alone

Other conditions: Hypertension, Renal Transplant
View official trial listing →
Completed NCT NCT00288184

Uric Acid in Essential Hypertension in Children

Not yet reported National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 30 participants Est. completion 2007-08 1 site Stand-alone

Other conditions: Essential Hypertension
View official trial listing →
Status unknown NCT NCT00346463

Antenatal Allopurinol in Intrauterine Growth Restriction

Not yet reported UMC Utrecht 50 participants Est. completion 2013-07 1 site

Other conditions: Fetal Growth Retardation
View official trial listing →
Completed NCT NCT00401388

A Trial of Perifosine in Patients With Chemo-Insensitive Sarcomas

Not yet reported AEterna Zentaris 72 participants Est. completion 2011-10 Stand-alone

Obstructive sleep apnea Other conditions: Alveolar Soft Part Sarcomas
View official trial listing →
Completed NCT NCT00430248

Efficacy and Safety of Oral Febuxostat in Participants With Gout

Not yet reported Takeda 2269 participants Est. completion 2008-03 258 sites

Other conditions: Gout
View official trial listing →
Completed NCT NCT00477789

Effects of Allopurinol on Diastolic Function in Chronic Heart Failure Patients

Not yet reported Universita di Verona 1 site

Heart failure
View official trial listing →
Completed NCT NCT00480883

Treatment of Cutaneous Leishmaniasis With Meglumine Antimoniate Versus Meglumine Antimoniate and Allopurinol

Not yet reported Combined Military Hospital, Pakistan 400 participants Est. completion 2008-12 1 site Stand-alone

Other conditions: Leishmaniasis, Cutaneous
View official trial listing →
Completed NCT NCT00512057

APEX Study: Effects of Allopurinol on Coronary and Peripheral Endothelial Function in Patients With Cardiac Syndrome X

Not yet reported University of Dundee 40 participants Est. completion 2010-06 1 site Stand-alone

Other conditions: Syndrome X
View official trial listing →
Completed NCT NCT00513474

Rasburicase in Preventing Graft-Versus-Host Disease in Patients With Hematologic Cancer or Other Disease Undergoing Donor Stem Cell Transplant

Not yet reported Massachusetts General Hospital 46 participants Est. completion 2013-02-12 1 site

Other conditions: Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Neoplasms
View official trial listing →
Completed NCT NCT00560079

Efficacy of Allopurinol and Dypiridamole in Acute Mania

Not yet reported Hospital Espirita de Porto Alegre 180 participants Est. completion 2006-04 1 site Stand-alone

Other conditions: Mania
View official trial listing →
Completed NCT NCT00602693

T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer

Not yet reported Masonic Cancer Center, University of Minnesota 41 participants Est. completion 2015-04-16 1 site Stand-alone

Other conditions: Leukemia, Lymphoma, Multiple Myeloma, Plasma Cell Neoplasm, Myelodysplastic Syndromes
View official trial listing →
Terminated NCT NCT00607152

Rasburicase (Fasturtec) Registration Trial

Not yet reported Sanofi 10 participants Est. completion 2009-01 1 site

Other conditions: Hyperuricemia
View official trial listing →
Completed NCT NCT00610363

Study of the Safety and Effectiveness of Rilonacept for the Prevention of Gout Flares

Not yet reported Regeneron Pharmaceuticals 83 participants Est. completion 2008-10 34 sites

Other conditions: Gout
View official trial listing →
Completed NCT NCT00639756

The Effect of Allopurinol on Insulin Resistance and Blood Pressure

Not yet reported Hospital Mateo Orfila 60 participants Est. completion 2008-10 1 site

Metabolic syndrome
View official trial listing →
Completed NCT NCT00643123

Allopurinol Add-on Treatment for Refractory Mania

Not yet reported Cedars-Sinai Medical Center 40 participants Est. completion 2010-06 1 site Stand-alone

Other conditions: Bipolar Disorder, Mixed Mania, Treatment-Resistant Mania
View official trial listing →
Terminated NCT NCT00652899

Allogeneic Natural Killer Cells in Patients With Recurrent Ovarian Cancer, Fallopian Tube, and Primary Peritoneal Cancer

Not yet reported Masonic Cancer Center, University of Minnesota 14 participants Est. completion 2009-08 1 site Stand-alone

Other conditions: Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity Cancer
View official trial listing →
Completed NCT NCT00688480

Do Xanthine Oxidase Inhibitors Reduce Both Left Ventricular Hypertrophy and Endothelial Dysfunction in Cardiovascular Patients With Renal Dysfunction?

Not yet reported A. D. Struthers 67 participants Est. completion 2010-02 1 site

Other conditions: Kidney Disease, Left Ventricular Hypertrophy
View official trial listing →
Terminated NCT NCT00732251

Allopurinol Maintenance Study for Bipolar Disorder

Not yet reported Cedars-Sinai Medical Center 15 participants Est. completion 2012-01 1 site Stand-alone

Other conditions: Bipolar Disorder, Mania, Mixed Mania
View official trial listing →
Terminated NCT NCT00768339

A Phase 1-2, Multicenter, Open-Label Study of AEG35156 in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia and Indolent B-Cell Lymphomas

Not yet reported, Not yet reported Aegera Therapeutics 25 participants Est. completion 2011-09 7 sites Stand-alone

Other conditions: Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, B-Cell
View official trial listing →
Completed NCT NCT00793585

A Controlled Study of Uric Acid on the Progression of IgA Nephropathy

Not yet reported Sun Yat-sen University 40 participants Est. completion 2009-06 1 site Stand-alone

Other conditions: IgA Nephropathy
View official trial listing →
Withdrawn NCT NCT00816413

Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer

Not yet reported, Not yet reported University of Nebraska Est. completion 2010-02 Stand-alone

Other conditions: Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic Syndromes, Nonmalignant Neoplasm
View official trial listing →
Completed NCT NCT00819585

A Study of the Efficacy of Canakinumab in Prevention of Acute Flares in Chronic Gout Patients Initiating Allopurinol Therapy (Core Study) and a Long-term Study of the Efficacy and Safety of Canakinumab in Patients With Gout (Extension Study)

Not yet reported Novartis Pharmaceuticals 432 participants Est. completion 2010-08 89 sites Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT00821392

Phase III Trial of Febuxostat in Korea Gout Patients

Not yet reported SK Chemicals Co., Ltd. 181 participants Est. completion 2007-09

Other conditions: Gout
View official trial listing →
Completed NCT NCT00823199

An Open Trial of Allopurinol in Patients With Poorly Responsive Schizophrenia

Not yet reported Bronx Psychiatric Center 10 participants Est. completion 2008-08

Other conditions: Schizophrenia
View official trial listing →
Completed NCT NCT00829829

PREventative Study Against URate-lowering Drug-induced Gout Exacerbations 1

Not yet reported Regeneron Pharmaceuticals 241 participants Est. completion 2010-06 91 sites

Other conditions: Intercritical Gout
View official trial listing →
Completed NCT NCT00849368

Azathioprine & Allopurinol in Inflammatory Bowel Disease Patients

Not yet reported University of Zurich 6 participants Est. completion 2011-09 1 site Stand-alone

Other conditions: Inflammatory Bowel Disease
View official trial listing →
Completed NCT NCT00855920

Study Utilizing Rilonacept in Gout Exacerbations

Not yet reported Regeneron Pharmaceuticals 225 participants Est. completion 2010-02 44 sites

Other conditions: Acute Gout Flare
View official trial listing →
Completed NCT NCT00856206

Review of Safety Using Rilonacept in Preventing Gout Exacerbations (RE-SURGE)

Not yet reported Regeneron Pharmaceuticals 1315 participants Est. completion 2011-01 124 sites

Other conditions: Gout
View official trial listing →
Completed NCT NCT00864825

Allopurinol in Schizophrenia: A Randomized Trial Administering Allopurinol vs Placebo as add-on Antipsychotics in Patients With Schizophrenia

Not yet reported Sheba Medical Center 248 participants Est. completion 2010-01 33 sites Stand-alone

Other conditions: Schizophrenia, Schizoaffective Disorder
View official trial listing →
Terminated NCT NCT00899431

Nonmyeloablative Stem Cell Transplantation for Chronic Lymphocytic Leukemia (CLL)

Not yet reported M.D. Anderson Cancer Center 39 participants Est. completion 2018-10-07 1 site

Other conditions: Chronic Lymphocytic Leukemia
View official trial listing →
Completed NCT NCT00919243

Prednisone for Heart Failure Patients With Hyperuricemia

Not yet reported Hebei Medical University 40 participants Est. completion 2010-08 1 site

Heart failure Other conditions: Hyperuricemia
View official trial listing →
Completed NCT NCT00940524

Induction Therapy With Cytarabine, High-Dose Mitoxantrone and Dasatinib for Patients With Philadelphia-Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

Not yet reported Memorial Sloan Kettering Cancer Center 7 participants Est. completion 2014-04 1 site Stand-alone

Other conditions: Leukemia, Acute Lymphoblastic Leukemia
View official trial listing →
Completed NCT NCT00958438

PREventative Study Against URate-Lowering Drug-Induced Gout Exacerbations (PRE-SURGE 2)

Not yet reported Regeneron Pharmaceuticals 248 participants Est. completion 2010-12 61 sites

Other conditions: Gout
View official trial listing →
Completed NCT NCT00978653

The Effect of Uric Acid Decrement on Endothelial Function in Patients With Chronic Renal Failure

Not yet reported Istanbul University 20 participants Est. completion 2009-05 1 site Stand-alone

Chronic kidney disease Other conditions: Hyperuricemia
View official trial listing →
Completed NCT NCT00987415

Using Allopurinol to Relieve Symptoms in Patients With Heart Failure and High Uric Acid Levels

Not yet reported Duke University 253 participants Est. completion 2014-06 10 sites

Heart failure Other conditions: Elevated Serum Uric Acid
View official trial listing →
Completed NCT NCT00997542

Allopurinol in Chronic Heart Failure

Not yet reported National Heart and Lung Institute 16 participants 1 site

Heart failure Other conditions: Hyperuricemia
View official trial listing →
Completed NCT NCT01001338

Allopurinol Combination Study

Not yet reported Ardea Biosciences, Inc. 227 participants Est. completion 2016-08 44 sites Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT01052272

Impact of Diabetes on Left Ventricular Remodeling

Not yet reported, Not yet reported University of Alabama at Birmingham 72 participants Est. completion 2010-11 1 site

Other conditions: Diabetes
View official trial listing →
Completed NCT NCT01052987

Study of Tranilast Alone or in Combination With Allopurinol in Subjects With Hyperuricemia

Not yet reported Nuon Therapeutics, Inc. 24 participants Est. completion 2010-11 3 sites Stand-alone

Other conditions: Gout, Hyperuricemia
View official trial listing →
Completed NCT NCT01077284

Febuxostat Versus Allopurinol or Placebo in Patients With Hyperuricosuria and Calcium Oxalate Stones

Not yet reported Takeda 99 participants Est. completion 2011-11 28 sites

Other conditions: Hyperuricosuria, Kidney Stones
View official trial listing →
Completed NCT NCT01092221

Allopurinol for Mania: A Randomized Trial Administering Allopurinol vs. Placebo as add-on to Mood Stabilizers and/or Antipsychotics in Patients in a Bipolar Manic Episode

Not yet reported Sheba Medical Center 180 participants Est. completion 2011-04 24 sites Stand-alone

Other conditions: Mania
View official trial listing →
Completed NCT NCT01101035

Cardiovascular Safety of Febuxostat and Allopurinol in Participants With Gout and Cardiovascular Comorbidities (CARES)

Not yet reported Takeda 6198 participants Est. completion 2017-07-18 203 sites

Cardiovascular disease
View official trial listing →
Completed NCT NCT01109121

Tranilast Plus Allopurinol in Patients With Moderate to Severe Gout (TAnGO)

Not yet reported Nuon Therapeutics, Inc. 112 participants Est. completion 2011-01 24 sites Stand-alone

Other conditions: Moderate to Severe Gout, Hyperuricemia
View official trial listing →
Completed NCT NCT01129648

Study to Evaluate sUA-Lowering Activity, Safety & PK Interaction of Oral BCX4208 & Allopurinol Admin. in Subjects w/Gout

Not yet reported BioCryst Pharmaceuticals 87 participants Est. completion 2010-11 18 sites Stand-alone

Other conditions: Gout
View official trial listing →
Status unknown NCT NCT01145274

A Pilot Study for Pharmacokinetic/Pharmacodynamic (PK/PD) Parameter of Allopurinol and Its Metabolite-oxypurinol After Once-daily Allopurinol in Chronic Kidney Disease Patient

Seoul National University Hospital 80 participants Est. completion 2013-02 1 site

Chronic kidney disease
View official trial listing →
Completed NCT NCT01147705

Allopurinol as a Possible Oxygen Sparing Agent During Exercise in Peripheral Arterial Disease

Not yet reported University of Dundee 50 participants Est. completion 2012-07 1 site

Other conditions: Peripheral Arterial Disease
View official trial listing →
Completed NCT NCT01157936

Hyperuricemia on Hypertension and Metabolic Syndrome

Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 40 participants Est. completion 2011-08 1 site

Metabolic syndrome Other conditions: Systolic and Diastolic Blood Pressure Levels, Uric Acid Levels, Hepatic Enzymes
View official trial listing →
Status unknown NCT NCT01188005

Inflammatory Mediators in Obstructive Sleep Apnoea Syndrome; Mechanisms of Production and the Effect of Long Term Antioxidants Administration

Not yet reported University of Athens 30 participants Est. completion 2010-10 1 site Stand-alone

Obstructive sleep apnea
View official trial listing →
Completed NCT NCT01200485

Rasburicase in Patients at High Risk for Tumor Lysis Syndrome (TLS) During Cycle-2

Not yet reported M.D. Anderson Cancer Center 55 participants Est. completion 2016-07 1 site Stand-alone

Other conditions: Leukemia, Lymphoma
View official trial listing →
Completed NCT NCT01228903

Uric Acid and the Endothelium in CKD

Not yet reported University of Colorado, Denver 80 participants Est. completion 2016-09 1 site

Other conditions: Kidney Disease
View official trial listing →
Completed NCT NCT01265264

Study to Evaluate sUA Lowering Activity, Safety and Efficacy of Oral Ulodesine Added to Allopurinol

Not yet reported BioCryst Pharmaceuticals 279 participants Est. completion 2013-02 54 sites Stand-alone

Other conditions: Gout, Hyperuricemia, Arthritis, Joint Disease
View official trial listing →
Completed NCT NCT01310673

Initiation of Allopurinol at First Medical Contact for Acute Attacks of Gout

Not yet reported White River Junction Veterans Affairs Medical Center 57 participants Est. completion 2009-07 1 site

Other conditions: Gout, Gout Acute
View official trial listing →
Completed NCT NCT01320722

Study of Vitamin D and Uric Acid Lowering on Kidney and Blood Vessel Function

Not yet reported Brigham and Women's Hospital 242 participants Est. completion 2015-06 1 site Stand-alone

Other conditions: Renal Function, Endothelial Function, Blood Pressure, Overweight, Obesity
View official trial listing →
Status unknown NCT NCT01332526

FFT, Inflammation, Lipid Metabolism, Blood Pressure and Organ Damage in Patients With Obesity, Chronic Kidney Disease (CKD).

Collegium Medicum w Bydgoszczy 70 participants

Chronic kidney diseaseMetabolic syndrome Other conditions: Obesity
View official trial listing →
Terminated NCT NCT01332799

Xanthine Oxidase Inhibition in Renal Transplant Recipients

Not yet reported Roberto S Kalil 20 participants Est. completion 2018-08-10 1 site

Other conditions: Complications of Renal Transplant
View official trial listing →
Completed NCT NCT01391325

Allopurinol Outcome Study

Not yet reported Ardea Biosciences, Inc. 1735 participants Est. completion 2013-03 173 sites

Other conditions: Gout
View official trial listing →
Completed NCT NCT01399008

Safety/Efficacy Study to Evaluate of MBX-102 in Combination With Allopurinol in Gout Patients

Not yet reported Gilead Sciences 100 participants Est. completion 2012-02 24 sites Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT01407874

A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency

Not yet reported BioCryst Pharmaceuticals 20 participants Est. completion 2012-07 10 sites Stand-alone

Other conditions: Gout, Hyperuricemia, Arthritis, Joint Disease, Renal Insufficiency
View official trial listing →
Completed NCT NCT01451645

Efficacy and Safety of Colchicine for the Prevention of Gout Flares During the Initiation of Allopurinol

Not yet reported Regeneron Pharmaceuticals 82 participants Est. completion 2012-09 37 sites

Other conditions: Intercritical Gout
View official trial listing →
Terminated NCT NCT01457820

Allopurinol in Acute Coronary Syndrome

Not yet reported Stephen McSwiggan 26 participants Est. completion 2015-03 1 site Stand-alone

Other conditions: Chronic Stable Angina
View official trial listing →
Terminated NCT NCT01459796

Study of the Safety and Efficacy of Long-Term Rilonacept Treatment for the Prevention of Gout Flares

Not yet reported Regeneron Pharmaceuticals 220 participants Est. completion 2013-06 74 sites Stand-alone

Other conditions: Gout
View official trial listing →
Terminated NCT NCT01464359

T-Cell Depleted Double UCB for Refractory AML

Not yet reported Masonic Cancer Center, University of Minnesota 3 participants Est. completion 2013-10 1 site Stand-alone

Other conditions: Acute Myelogenous Leukemia, Refractory Acute Myelogenous Leukemia
View official trial listing →
Completed NCT NCT01493531

Combining Lesinurad With Allopurinol in Inadequate Responders

Not yet reported Ardea Biosciences, Inc. 610 participants Est. completion 2014-07 175 sites Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT01510158

Combining Lesinurad With Allopurinol in Inadequate Responders

Not yet reported Ardea Biosciences, Inc. 607 participants Est. completion 2014-08 165 sites Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT01550107

Allopurinol in Functional Impairment (ALFIE) Trial: 'Improving Muscle Strength'

Not yet reported University of Dundee 124 participants Est. completion 2017-09-20 1 site

Other conditions: Sarcopenia
View official trial listing →
Terminated NCT NCT01564277

Rasburicase and Allopurinol in Treating Patients With Hematologic Malignancies

Not yet reported Roswell Park Cancer Institute 24 participants Est. completion 2016-05-28 1 site Stand-alone

Other conditions: Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities, Adult Acute Myeloid Leukemia With Del(5q), Adult Acute Myeloid Leukemia With Inv(16)(p13;q22), Adult Acute Myeloid Leukemia With t(15;17)(q22;q12), Adult Acute Myeloid Leukemia With t(16;16)(p13;q22), Adult Acute Myeloid Leukemia With t(8;21)(q22;q22), Blastic Phase Chronic Myelogenous Leukemia, Contiguous Stage II Adult Burkitt Lymphoma, de Novo Myelodysplastic Syndromes, Noncontiguous Stage II Adult Burkitt Lymphoma, Previously Treated Myelodysplastic Syndromes, Recurrent Adult Acute Lymphoblastic Leukemia, Recurrent Adult Acute Myeloid Leukemia, Recurrent Adult Burkitt Lymphoma, Stage I Adult Burkitt Lymphoma, Stage III Adult Burkitt Lymphoma, Stage IV Adult Burkitt Lymphoma, Untreated Adult Acute Lymphoblastic Leukemia, Untreated Adult Acute Myeloid Leukemia
View official trial listing →
Completed NCT NCT01603134

Bioequivalence Study of Allopurinol 300 mg Tablets USP Under Fasting Condition

Not yet reported IPCA Laboratories Ltd. 32 participants Est. completion 2008-04 1 site Stand-alone

Other conditions: Fasting State
View official trial listing →
Completed NCT NCT01609166

Effectiveness Allopurinol Topical Agent Prevention Capecitabine-induced Hand-foot Syndrome

Not yet reported Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau 60 participants Est. completion 2012-12 1 site Stand-alone

Other conditions: Hand-foot Syndrome
View official trial listing →
Completed NCT NCT01623492

Eisenmenger Quality Enhancement Research Initiative

Actelion 193 participants Est. completion 2018-04-17

Other conditions: Pulmonary Arterial Hypertension
View official trial listing →
Completed NCT NCT01637623

Study of Cardiovascular Disease and Obstructive Sleep Apnea

Not yet reported University of Wisconsin, Madison 87 participants Est. completion 2015-06 4 sites

Obstructive sleep apnea Other conditions: Hypertension
View official trial listing →
Terminated NCT NCT01685411

Busulfan and Cyclophosphamide Followed By ALLO BMT

Not yet reported Masonic Cancer Center, University of Minnesota 5 participants Est. completion 2020-02-10 1 site Stand-alone

Other conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Myelodysplastic Syndrome
View official trial listing →
Terminated NCT NCT01701622

The Blood Pressure Effects of Febuxostat in Patients Previously Treated With Allopurinol: A Pilot Study

Not yet reported University of Mississippi Medical Center 1 participants Est. completion 2011-10 1 site Stand-alone

Other conditions: Blood Pressure, Gout
View official trial listing →
Completed NCT NCT01724528

Febuxostat for Tumor Lysis Syndrome Prevention in Hematologic Malignancies

Not yet reported Menarini Group 346 participants Est. completion 2013-10

Other conditions: Tumor Lysis Syndrome
View official trial listing →
Completed NCT NCT01736514

A Study to Evaluate Safety and Efficacy of Oral Febuxostat in Patients With Gout

Not yet reported Astellas Pharma Taiwan, Inc. 109 participants Est. completion 2012-02 4 sites

Other conditions: Gout
View official trial listing →
Withdrawn NCT NCT01775098

Allopurinol in Acute Gout

Not yet reported Université de Sherbrooke Est. completion 2013-02 Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT01808131

Lesinurad and Allopurinol Combination Extension Study in Gout

Not yet reported Ardea Biosciences, Inc. 717 participants Est. completion 2016-11 207 sites Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT01951404

Does ALlopurinol Regress lefT Ventricular Hypertrophy in End Stage REnal Disease: The ALTERED Study

Not yet reported University of Dundee 80 participants Est. completion 2016-08 3 sites

Other conditions: End Stage Renal Disease, Left Ventricular Hypertrophy
View official trial listing →
Completed NCT NCT01987570

Effect of Allopurinol Administration on the Prevention of Muscle Mass Loss in Subject Immobilized.

Not yet reported Instituto de Investigacion Sanitaria La Fe 53 participants Est. completion 2016-07 2 sites Stand-alone

Other conditions: Patients With Grade II Ankle Sprain
View official trial listing →
Completed NCT NCT01988402

Does Allopurinol Prolong a Treated, Acute Gout Flare?

Not yet reported 59th Medical Wing 35 participants Est. completion 2013-06 1 site

Other conditions: Gout
View official trial listing →
Status unknown NCT NCT02008968

Effect of Allopurinol Treatment on Insulin Resistance

Not yet reported Istanbul Medeniyet University 130 participants Est. completion 2014-08 1 site

Prediabetes Other conditions: Hyperuricemia, Insulin Resistance
View official trial listing →
Completed NCT NCT02017171

A Multicenter Clinical Trial of Allopurinol to Prevent Kidney Function Loss in Type 1 Diabetes

Not yet reported Alessandro Doria 530 participants Est. completion 2019-08-31 30 sites Stand-alone

Cardiovascular disease Other conditions: Diabetic Nephropathies
View official trial listing →
Completed NCT NCT02038179

Center of Research Translation (CORT) Project 2

Not yet reported, Not yet reported University of Alabama at Birmingham 99 participants Est. completion 2018-08 1 site Stand-alone

Other conditions: Pre-hypertension, JNC 7 Stage I Hypertension
View official trial listing →
Completed NCT NCT02046694

A Pilot Study of Allopurinol As A Modifier of 6-MP Metabolism in Pediatric ALL

Not yet reported Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 34 participants Est. completion 2020-04-06 3 sites Stand-alone

Other conditions: Acute Lymphoblastic Leukemia (ALL)
View official trial listing →
Completed NCT NCT02063997

Evaluate the Efficacy and Safety of Arhalofenate for Preventing Flares and Reducing Serum Uric Acid in Gout Patients

Not yet reported Gilead Sciences 248 participants Est. completion 2015-01 56 sites

Other conditions: Gout
View official trial listing →
Completed NCT NCT02078219

Phase II Dose Finding Study of RDEA3170 Versus Placebo in Japanese Patients With Gout or Asymptomatic Hyperuricemia

Not yet reported AstraZeneca 204 participants Est. completion 2015-03-13 14 sites

Other conditions: Gout and Hyperuricemia
View official trial listing →
Completed NCT NCT02082769

Safety and Efficacy of Oral Febuxostat in Subjects With Gout

Not yet reported Xijing Hospital 504 participants Est. completion 2013-10

Other conditions: Gout
View official trial listing →
Completed NCT NCT02122718

XILO-FIST, the Effect of Allopurinol on the Brain Heart and Blood Pressure After Stroke

Not yet reported NHS Greater Glasgow and Clyde 464 participants Est. completion 2021-02 21 sites Stand-alone

Cardiovascular disease
View official trial listing →
Completed NCT NCT02129764

Prednisone for Heart Failure Patients With Hyperuricemia

Not yet reported, Not yet reported Hebei Medical University 205 participants Est. completion 2018-08-31 1 site

Heart failure
View official trial listing →
Completed NCT NCT02214407

Randomized Phase III Study of Decitabine +/- Hydroxyurea (HY) Versus HY in Advanced Proliferative CMML

Not yet reported Groupe Francophone des Myelodysplasies 170 participants Est. completion 2021-08-16 45 sites Stand-alone

Other conditions: MDS
View official trial listing →
Completed NCT NCT02237339

Does Allopurinol Reduce Thickening of the Left Ventricle of the Heart in Patient With Treated Hypertension?

Not yet reported University of Dundee 72 participants Est. completion 2017-06 1 site

Other conditions: Hypertension, Hypertrophy, Left Ventricular
View official trial listing →
Completed NCT NCT02279641

RDEA3170 and Allopurinol Combination Study in Gout Subjects

Not yet reported Ardea Biosciences, Inc. 12 participants Est. completion 2015-09-11 1 site Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT02371421

Genetics of Hyperuricemia Therapy in Hmong

University of Minnesota 80 participants Est. completion 2016-12 1 site

Other conditions: Hyperuricemia, Gout
View official trial listing →
Completed NCT NCT02373384

The Predictors of Successful Oral Dissolution Therapy in Radiolucent Renal Stones; A Prospective Evaluation

Not yet reported Mansoura University 182 participants Est. completion 2017-06 1 site Stand-alone

Other conditions: Urolithiasis, Renal Stones
View official trial listing →
Completed NCT NCT02393560

DECT Study in Allopurinol-Treated Gout Patients

Ardea Biosciences, Inc. 223 participants Est. completion 2016-10 10 sites

Other conditions: Gout
View official trial listing →
Completed NCT NCT02398448

IVIVR Assessing PK Parameters Used to Establish Bioequivalence

Not yet reported Ardea Biosciences, Inc. 20 participants Est. completion 2015-09 1 site Stand-alone

Other conditions: Healthy
View official trial listing →
Completed NCT NCT02477488

Optimal Administration of Allopurinol in Dialysis Patients

Not yet reported Maisonneuve-Rosemont Hospital 50 participants Est. completion 2015-08 1 site Stand-alone

Other conditions: Gout, Renal Insufficiency
View official trial listing →
Completed NCT NCT02498652

Phase 2a RDEA3170 and Allopurinol Combination Study in Gout Subjects

Not yet reported Ardea Biosciences, Inc. 41 participants Est. completion 2016-06-02 4 sites Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT02500641

Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout

Not yet reported Menarini International Operations Luxembourg SA 196 participants Est. completion 2017-05-10 26 sites

Other conditions: Gout
View official trial listing →
Completed NCT NCT02533648

Role of Allopurinol on Oxidative Stress and Mitochondrial Alterations in Skeletal Muscle of Diabetic Patients

Not yet reported Hospices Civils de Lyon 31 participants Est. completion 2016-02-18 1 site Stand-alone

Type 2 diabetes
View official trial listing →
Completed NCT NCT02579096

CSP594 Comparative Effectiveness in Gout: Allopurinol vs. Febuxostat

Not yet reported VA Office of Research and Development 950 participants Est. completion 2021-04-15 23 sites

Chronic kidney disease Other conditions: Gout
View official trial listing →
Completed NCT NCT02581553

Lesinurad/Allopurinol 200/300 FDC Tablets Bioavailability

Not yet reported Ardea Biosciences, Inc. 116 participants Est. completion 2016-08 1 site Stand-alone

Other conditions: Healthy
View official trial listing →
Completed NCT NCT02600780

Zurig (Febuxostat) 40mg Efficacy and Safety Trial

Not yet reported Getz Pharma 50 participants Est. completion 2015-03 1 site

Other conditions: Hyperuricemia
View official trial listing →
Completed NCT NCT02661035

Allo HSCT Using RIC for Hematological Diseases

Not yet reported Masonic Cancer Center, University of Minnesota 156 participants Est. completion 2023-05-29 1 site Stand-alone

Other conditions: Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Plasma Cell Leukemia, Myelodysplastic Syndromes, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, B-Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Leukemia, Lymphoblastic Lymphoma, Burkitt's Lymphoma, Non-Hodgkin's Lymphoma, Multiple Myeloma, Myeloproliferative Syndromes, Hematological Diseases
View official trial listing →
Completed NCT NCT02700347

Whole Blood Bactericidal Activity Against Mycobacterium Tuberculosis of Pyrazinamide Plus Allopurinol in Healthy Volunteers

Not yet reported National University Hospital, Singapore 12 participants Est. completion 2016-04 1 site Stand-alone

Other conditions: Tuberculosis
View official trial listing →
Completed NCT NCT02752633

Effect of Allopurinol and Febuxostat on Urinary 2,8-Dihydroxyadenine Excretion

Not yet reported Landspitali University Hospital 9 participants Est. completion 2015-05 1 site Stand-alone

Other conditions: Adenine Phosphoribosyltransferase Deficiency
View official trial listing →
Completed NCT NCT02790463

Virtual Gout Clinic

Not yet reported University of Alabama at Birmingham 1463 participants Est. completion 2018-10 2 sites

Other conditions: Gout
View official trial listing →
Status unknown NCT NCT02797028

Investigation of the Atherogenic Effects of Uric Acid-modified in Endothelial Dysfunction and the the Preventional Mechanism by Anthocyanidines

Not yet reported Guangzhou General Hospital of Guangzhou Military Command 320 participants Est. completion 2017-12 1 site Stand-alone

Cardiovascular disease
View official trial listing →
Completed NCT NCT02829177

Microalbuminuria and Allopurinol in Type 1 Diabetes

Not yet reported Peter Rossing 30 participants Est. completion 2017-09-20 1 site

Chronic kidney disease Other conditions: Type 1 Diabetes
View official trial listing →
Completed NCT NCT02888054

Lesinurad/Allopurinol 200/300 FDC Tablets Bioequivalence

Not yet reported Ardea Biosciences, Inc. 28 participants Est. completion 2017-02-01 1 site Stand-alone

Other conditions: Healthy
View official trial listing →
Terminated NCT NCT02953509

Trial of Magrolimab (Hu5F9-G4) in Combination With Rituximab or Rituximab + Chemotherapy in Participants With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Not yet reported, Not yet reported Gilead Sciences 178 participants Est. completion 2024-03-25 20 sites Stand-alone

Other conditions: Non Hodgkin Lymphoma
View official trial listing →
Completed NCT NCT02956278

The Effects of BCRP Q141K on Allopurinol Pharmacokinetics and Dynamics

Not yet reported University of California, San Francisco 27 participants Est. completion 2018-03 1 site Stand-alone

Other conditions: Chronic Gout, Hyperuricemia
View official trial listing →
Terminated NCT NCT02991898

Adoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme Malignancies

Not yet reported Masonic Cancer Center, University of Minnesota 3 participants Est. completion 2019-06-20 1 site Stand-alone

Other conditions: Acute Lymphoblastic Leukemia, Burkitt Lymphoma, Natural Killer Cell Malignancies, Chronic Myelogenous Leukemia, Myelodysplastic Syndromes, Large-cell Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Marginal Zone B-Cell Lymphoma, Follicular Lymphoma, Lymphoplasmacytic Lymphoma, Mantle-Cell Lymphoma, Prolymphocytic Leukemia, Hodgkin Lymphoma, Multiple Myeloma, Acute Myelogenous Leukemia, Biphenotypic Leukemia, Undifferentiated Leukemia
View official trial listing →
Completed NCT NCT02992652

Allopurinol in Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis

Not yet reported Ain Shams University 100 participants Est. completion 2014-12

Other conditions: Endoscopic Retrograde Cholangiopancreatography
View official trial listing →
Status unknown NCT NCT03022747

Optimizing 6-mercaptopurine Therapy in Pediatric Acute Lymphoblastic Leukemia by Using Allopurinol

Not yet reported Vastra Gotaland Region 60 participants Est. completion 2019-04 3 sites Stand-alone

Other conditions: Lymphoblastic Leukemia, Acute, Childhood
View official trial listing →
Status unknown NCT NCT03046914

HLA-B*5801 Screening to Prevent Allopurinol-induced Severe Cutaneous Adverse Reaction

Not yet reported Seoul National University Hospital 600 participants Est. completion 2017-11-30 1 site Stand-alone

Other conditions: Stevens-Johnson Syndrome, Kidney Failure, Chronic
View official trial listing →
Withdrawn NCT NCT03076684

Gender Differences in the Metabolic Effects of Uric Acid

Not yet reported University of Missouri-Columbia Est. completion 2019-03-13 1 site Stand-alone

Other conditions: Hyperuricemia
View official trial listing →
Status unknown NCT NCT03101800

Beneficial and Harmful Effects of Azathioprine and Allopurinol Versus Standard Azathioprine Therapy for Patients With Ulcerative Colitis

Not yet reported Hvidovre University Hospital 84 participants Est. completion 2019-12-14 1 site Stand-alone

Other conditions: Colitis, Ulcerative, Colitis Ulcerative Exacerbation
View official trial listing →
Status unknown NCT NCT03162653

Effect of Allopurinol for Hypoxic-ischemic Brain Injury on Neurocognitive Outcome

Not yet reported University Hospital Tuebingen 760 participants Est. completion 2026-01-31 12 sites

Other conditions: Encephalopathy, Hypoxic-Ischemic, Infant, Newborn, Diseases
View official trial listing →
Status unknown NCT NCT03195153

Effect of Allopurinol on Mono and Co-administration With Statins on Platelets Reactivity on Diabetic Patiets Treated With Aspirin and Insulin

Not yet reported University of Roma La Sapienza 200 participants Est. completion 2017-07-15 1 site Stand-alone

Type 2 diabetes
View official trial listing →
Terminated NCT NCT03226899

A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment

Not yet reported Ironwood Pharmaceuticals, Inc. 242 participants Est. completion 2019-02-25 116 sites

Chronic kidney disease Other conditions: Gout
View official trial listing →
Completed NCT NCT03272425

Lesinurad/Allopurinol 200/300 Fixed-Dose Combination (FDC) Tablets Bioequivalence.

Not yet reported Ardea Biosciences, Inc. 32 participants Est. completion 2017-10-04 1 site Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT03334318

PERL Continuous Glucose Monitoring (CGM) Study

Joslin Diabetes Center 175 participants Est. completion 2021-12-31 19 sites

Other conditions: Diabetic Nephropathies
View official trial listing →
Status unknown NCT NCT03336203

The Impact of Urate-lowering Therapy on Kidney Function (IMPULsKF)

Not yet reported Medical Practice Prof D. Ivanov 2 participants Est. completion 2022-12-31 1 site

Chronic kidney disease Other conditions: Gout, SUA Level (>8 mg/dL; 480 µmol/L)
View official trial listing →
Completed NCT NCT03353298

Lowering Uric Acid in Live Kidney Donors

Not yet reported Oslo University Hospital 71 participants Est. completion 2020-09-25 1 site

Other conditions: Renal Transplant Donor of Left Kidney, Renal Transplant Donor of Right Kidney
View official trial listing →
Status unknown NCT NCT03385135

Allopurinol and Endothelial Function in Diabetic CAD Patients

Not yet reported University Tunis El Manar 58 participants Est. completion 2018-06 1 site

Cardiovascular disease Other conditions: Diabetes Mellitus
View official trial listing →
Completed NCT NCT03465527

Pre-phase Treatment Before R-CHOP Chemotherapy in Elderly Patients With Newly Diagnosed DLBCL

Not yet reported Kosin University Gospel Hospital 37 participants Est. completion 2021-07-13 1 site Stand-alone

Other conditions: Diffuse Large B Cell Lymphoma
View official trial listing →
Status unknown NCT NCT03506919

Comparative Clinical Efficacy and Safety of Coded Polyherbal Medicine for the Management of Arthritis

Not yet reported, Not yet reported Shifa Ul Mulk Memorial Hospital 200 participants Est. completion 2018-06-30 1 site Stand-alone

Other conditions: Treatment of Arthritis
View official trial listing →
Status unknown NCT NCT03570983

A Trial Comparing Single Agent Melphalan to Carmustine, Etoposide, Cytarabine, and Melphalan (BEAM) as a Preparative Regimen for Patients With Multiple Myeloma Undergoing High Dose Therapy Followed by Autologous Stem Cell Reinfusion

Not yet reported Swedish Medical Center 100 participants Est. completion 2024-12 1 site Stand-alone

Other conditions: Multiple Myeloma
View official trial listing →
Status unknown NCT NCT03601260

The Percentage of Cases of Acute Treatment With Allopurinol in Gout Patients

Not yet reported Hillel Yaffe Medical Center 700 participants Est. completion 2018-12 1 site

Other conditions: Gout
View official trial listing →
Completed NCT NCT03648996

Sex-related Differences in Arterial Stiffness in Type 2 Diabetics: Role of Uric Acid

Not yet reported University of Missouri-Columbia 34 participants Est. completion 2022-03-10 1 site Stand-alone

Type 2 diabetes Other conditions: Hyperuricemia
View official trial listing →
Completed NCT NCT03680404

The Effect of Local Antioxidant Therapy on Racial Differences in Vasoconstriction

Not yet reported The University of Texas at Arlington 24 participants Est. completion 2020-02-01 1 site Stand-alone

Cardiovascular disease Other conditions: Cardiovascular Risk Factor, Vasoconstriction
View official trial listing →
Completed NCT NCT03680573

The Effect of Antioxidants on Skin Blood Flow-BH4

Not yet reported The University of Texas at Arlington 16 participants Est. completion 2018-05-05 1 site Stand-alone

Cardiovascular disease Other conditions: Cardiovascular Risk Factor, Vasoconstriction
View official trial listing →
Completed NCT NCT03680638

The Effect of Antioxidants on Skin Blood Flow During Local Heating

Not yet reported The University of Texas at Arlington 44 participants Est. completion 2017-10-09 1 site Stand-alone

Cardiovascular disease Other conditions: Cardiovascular Risk Factor, Vasodilation
View official trial listing →
Status unknown NCT NCT03700645

Allopurinol in Diabetes Mellitus and Multivessel Coronary Artery Disease

Not yet reported Tel-Aviv Sourasky Medical Center 100 participants Est. completion 2020-01-31

Cardiovascular disease Other conditions: Diabetes Mellitus, Ischemic Heart Disease
View official trial listing →
Completed NCT NCT03745729

Allopurinol in Acute Coronary Syndrome

Not yet reported Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 162 participants Est. completion 2022-07-15 1 site Stand-alone

Other conditions: Acute Coronary Syndrome
View official trial listing →
Status unknown NCT NCT03767322

Effect of Allopurinol or Febuxostat to Prevent Contrast Induced Acute Kidney Injury (CI-AKI)

Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 558 participants Est. completion 2019-12 1 site

Other conditions: Contrast-induced Nephropathy, Contrast-induced Acute Kidney Injury
View official trial listing →
Completed NCT NCT03776656

Evaluation of a Treatment With Allopurinol in Adenylosuccinate Lyase Deficiency

Not yet reported Assistance Publique - Hôpitaux de Paris 8 participants Est. completion 2022-06-17 2 sites Stand-alone

Other conditions: Adenylosuccinate Lyase Deficiency
View official trial listing →
Completed NCT NCT03836599

A Study to Assess the Safety and Pharmacokinetics of Verinurad and Allopurinol in Asian and Chinese Subjects

Not yet reported AstraZeneca 6 participants Est. completion 2019-04-26 1 site Stand-alone

Chronic kidney disease
View official trial listing →
Terminated NCT NCT03865407

Uric Acid Reduction as a Novel Treatment for Pediatric Chronic Kidney Disease

Not yet reported Virginia Commonwealth University 17 participants Est. completion 2020-10-07 1 site

Chronic kidney disease Other conditions: Hyperuricemia
View official trial listing →
Completed NCT NCT03990363

A Study of Verinurad and Allopurinol in Patients With Chronic Kidney Disease and Hyperuricaemia

Not yet reported AstraZeneca 861 participants Est. completion 2021-11-22 165 sites Stand-alone

Chronic kidney disease
View official trial listing →
Status unknown NCT NCT04012294

Effects of Allopurinol on Inflammation and Ultrasonographic Changes in People With Elevated Uric Acid But no Symptoms

Not yet reported Instituto Nacional de Cardiologia Ignacio Chavez 200 participants Est. completion 2021-02-28 2 sites Stand-alone

Other conditions: Musculoskeletal Degeneration, Inflammation, Hyperuricemia
View official trial listing →
Completed NCT NCT04040816

Placebo Controlled, Multiple Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAP-001 in Gout Patients

Not yet reported Shanton Pharma Co., Ltd. 40 participants Est. completion 2020-08-30 6 sites Stand-alone

Other conditions: Gout, Hyperuricemia
View official trial listing →
Completed NCT NCT04052932

A Study of Evaluating the Efficacy and Safety of SHR4640 in Subjects With Gout

Not yet reported Jiangsu HengRui Medicine Co., Ltd. 594 participants Est. completion 2021-07-14 1 site

Other conditions: Gout
View official trial listing →
Withdrawn NCT NCT04072471

Post-Authorisation Safety Study of Lesinurad

AstraZeneca Est. completion 2023-06-30

Other conditions: Gout, Hyperuricemia
View official trial listing →
Completed NCT NCT04155918

Phase 2a Study of AR882 Alone and in Combination With Febuxostat or Allopurinol in Gout Patients

Not yet reported Arthrosi Therapeutics 30 participants Est. completion 2020-09-03 1 site Stand-alone

Other conditions: Gout Patients
View official trial listing →
Status unknown NCT NCT04213534

The Influence of Urate-lowering Therapy on Sperm Quality of Male Gouty Patients：A Prospective Cohort Study

Peking University Third Hospital 60 participants Est. completion 2023-12 1 site

Other conditions: Gout
View official trial listing →
Completed NCT NCT04256629

A Study to Assess the Effect of Verinurad on the Electric Activity of the Heart

Not yet reported AstraZeneca 24 participants Est. completion 2020-08-21 1 site Stand-alone

Chronic kidney disease
View official trial listing →
Completed NCT NCT04327024

Study of Verinurad in Heart Failure With Preserved Ejection Fraction

Not yet reported AstraZeneca 159 participants Est. completion 2022-04-29 58 sites Stand-alone

Heart failure
View official trial listing →
Completed NCT NCT04347005

The Study is Designed to Evaluate Single Ascending Doses of AR882 in Healthy Adult Males

Not yet reported Arthrosi Therapeutics 64 participants Est. completion 2019-07-31 1 site Stand-alone

Other conditions: Healthy Volunteers
View official trial listing →
Status unknown NCT NCT04368819

Allopurinol in Patients With Refractory Angina to Improve Ischemic Symptoms

Not yet reported, Not yet reported Ministry of Health, Brazil 40 participants Est. completion 2021-12-31 1 site

Other conditions: Refractory Angina
View official trial listing →
Completed NCT NCT04532918

Pharmacokinetics of Verinurad and Allopurinol in Combination With Cyclosporine and Rifampicin in Healthy Volunteers

Not yet reported AstraZeneca 14 participants Est. completion 2020-11-23 1 site Stand-alone

Chronic kidney disease
View official trial listing →
Completed NCT NCT04550234

A Study in Healthy Subjects to Assess Drug Availability of 4 Different Formulations of Verinurad and Allopurinol

Not yet reported AstraZeneca 25 participants Est. completion 2021-07-15 1 site Stand-alone

Chronic kidney disease
View official trial listing →
Completed NCT NCT04621929

Phentermine/Topiramate for Uric Acid Stones

Not yet reported University of Florida 19 participants Est. completion 2024-11-14 1 site

Type 2 diabetesPrediabetes Other conditions: Obesity, Uric Acid Stones
View official trial listing →
Completed NCT NCT04699383

Documentation of Patient Outcomes for SSG/Allopurinol Combination Treatment in Ethiopia

Institute of Tropical Medicine, Belgium 105 participants Est. completion 2022-12-15 1 site

Other conditions: Cutaneous Leishmaniasis
View official trial listing →
Active, not recruiting NCT NCT04733079

Treat-to-target by Email During Urate-lowering Therapy in Gout

Not yet reported Assistance Publique - Hôpitaux de Paris 204 participants Est. completion 2026-12-31 2 sites

Other conditions: Gout, Inflammatory Rheumatism, Hyperuricemia, Posology Adjustment
View official trial listing →
Completed NCT NCT04746989

Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines - (DREAM) Probenecid vs Allopurinol

Brigham and Women's Hospital 294878 participants Est. completion 2023-12-31 1 site

Other conditions: Gout
View official trial listing →
Completed NCT NCT04853160

Drug Use Study of Febuxostat After Recent Changes in the Prescribing Information

Takeda 24046 participants Est. completion 2021-01-05 1 site

Cardiovascular disease Other conditions: Gout
View official trial listing →
Status unknown NCT NCT04853615

SGLT2 Inhibitors Prophylaxis Against Post-contrast Acute Kidney Injury in Diabetic Kidney Disease?

Fayoum University 800 participants Est. completion 2024-08-01

Other conditions: SGLT2i Kideny Protection Against Contrast in Diabetic Kidney
View official trial listing →
Completed NCT NCT04956432

A Multicentre, Randomized, Double-blind, Allopurinol Controlled Study to Evaluate the Efficacy and Safety of SHR4640 in Subjects With Gout

Not yet reported Jiangsu HengRui Medicine Co., Ltd. 779 participants Est. completion 2024-08-23 1 site Stand-alone

Other conditions: Gout
View official trial listing →
Completed NCT NCT04983160

Crossover Clinical Trial, Randomized, Double Blind, Placebo Controlled Trial

Not yet reported Maimónides Biomedical Research Institute of Córdoba 22 participants Est. completion 2016-04-29 1 site

Chronic kidney disease
View official trial listing →
Terminated NCT NCT05049863

Chemotherapy in Patients With Relapsed Small Cell Lung Cancer in Combination With Allopurinol and MycoPhenolate (CLAMP Trial)

Not yet reported Washington University School of Medicine 17 participants Est. completion 2024-11-17 1 site Stand-alone

Other conditions: Small-cell Lung Cancer, Small Cell Lung Carcinoma
View official trial listing →
Active, not recruiting NCT NCT05053659

Loncastuximab Tesirine and Venetoclax for Relapsed/ Refractory Non-Hodgkin Lymphoma

Not yet reported Paolo Caimi, MD 23 participants Est. completion 2026-11 1 site Stand-alone

Other conditions: Relapsed Non Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma
View official trial listing →
Status unknown NCT NCT05193838

Effect of Allopurinol on Left Ventricular Function in Children With Dilated Cardiomyopathy

Assiut University 100 participants Est. completion 2023-07

Other conditions: Dilated Cardiomyopathy
View official trial listing →
Completed NCT NCT05253833

Phase 2 to Assess Efficacy and Safety in AR882 Alone or in Combination With Allopurinol in Patients With Tophaceous Gout

Not yet reported Arthrosi Therapeutics 42 participants Est. completion 2024-10-28 12 sites Stand-alone

Other conditions: Gout, Arthritis, Gouty, Hyperuricemia, Gout Chronic
View official trial listing →
Completed NCT NCT05360628

Evaluation of PK and Safety of D-0120 and Allopurinol

Not yet reported InventisBio Co., Ltd 20 participants Est. completion 2022-07-23 1 site Stand-alone

Other conditions: Healthy
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Completed NCT NCT05365477

Empiric Versus Selective Prevention Strategies for Kidney Stone Disease

Not yet reported Vanderbilt University Medical Center 56 participants Est. completion 2026-03-31 1 site Stand-alone

Other conditions: Kidney Stones, Nephrolithiasis
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Completed NCT NCT05414669

Allopurinol Effect on MDA,NO,KIM-1 Urine Levels, RI and Renal Elastography in Kidney Stone Patients Post ESWL

Not yet reported RSUP Prof. Dr. I.G.N.G. Ngoerahal 35 participants Est. completion 2021-04-20 1 site Stand-alone

Other conditions: Kidney Calculi
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Completed NCT NCT05474560

Febuxostat Versus Allopurinol on Hepatic Steatosis in MAFLD Patients

Not yet reported Ain Shams University 90 participants Est. completion 2023-01-28 1 site Stand-alone

Other conditions: Non-Alcoholic Fatty Liver Disease, Hyperuricemia
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Active, not recruiting NCT NCT05507723

Tight Control of Gouty Arthritis Compared to Usual Care

Not yet reported University of Edinburgh 125 participants Est. completion 2028-12-31 1 site Stand-alone

Other conditions: Gout
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Completed NCT NCT05511766

Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis

Not yet reported, Not yet reported Tanta University 150 participants Est. completion 2026-01-25 1 site

Other conditions: Cirrhosis, Hepatic Encephalopathy, Ascites, Varices, SBP - Spontaneous Bacterial Peritonitis
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Status unknown NCT NCT05540184

Allopurinol and Trimetazidine as a Preventive of Acute Kidney Injury in PCI Patients

Not yet reported Beni-Suef University 124 participants Est. completion 2025-09 1 site Stand-alone

Other conditions: AKI - Acute Kidney Injury
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Completed NCT NCT05545670

Allopurinol to Prevent Cirrhosis Related Morbidities

Not yet reported, Not yet reported Tanta University 100 participants Est. completion 2023-03-01 1 site

Other conditions: Cirrhosis
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Completed NCT NCT05586971

Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients

Not yet reported LG Chem 2202 participants Est. completion 2025-05-06 279 sites

Other conditions: Gout, Hyperuricemia, Gout Flare, Tophi
View official trial listing →
Completed NCT NCT05601271

Effect of Allopurinol on Markers of Mineral and Bone Metabolism

Not yet reported University of Sao Paulo General Hospital 50 participants Est. completion 2025-03-01 1 site

Chronic kidney disease Other conditions: Osteodystrophy, Uric Acid Concentration, Serum, Quantitative Trait Locus 7
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Completed NCT NCT05665699

Phase II Study to Evaluate Efficacy and Safety of D-0120 in Combination With Allopurinol in Subjects With Gout

Not yet reported InventisBio Co., Ltd 80 participants Est. completion 2025-12-30 19 sites Stand-alone

Other conditions: Gout
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Active, not recruiting NCT NCT05734495

Pirtobrutinib and Venetoclax in Waldenström Macroglobulinemia

Not yet reported Dana-Farber Cancer Institute 46 participants Est. completion 2033-01-25 2 sites Stand-alone

Other conditions: Waldenstrom Macroglobulinemia
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Completed NCT NCT05818085

Phase 2b/3 Study to Assess ABP-671 a Novel URAT1 Inhibitor in Participants With Gout

Not yet reported, Not yet reported Atom Therapeutics Co., Ltd 300 participants Est. completion 2025-03-30 57 sites

Other conditions: Gout
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Completed NCT NCT05828836

Allopurinol and Quality of Life in Liver Cirrhosis

Not yet reported, Not yet reported Tanta University 100 participants Est. completion 2023-03-01 1 site

Other conditions: Cirrhosis, Liver
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Completed NCT NCT05888233

Allopurinol Improves Heart Function in African Americans With Resistant Hypertension

Not yet reported VA Office of Research and Development 40 participants Est. completion 2026-08-31 1 site Stand-alone

Heart failure Other conditions: Resistant Hypertension
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Completed NCT NCT06056570

Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients With Hyperuricemia

Not yet reported, Not yet reported Urica Therapeutics Inc. 20 participants Est. completion 2024-07-09 4 sites Stand-alone

Other conditions: Gout, Hyperuricemia
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Terminated NCT NCT06276556

Extension Study of ABP-671 in Participants With Gout

Not yet reported, Not yet reported Atom Therapeutics Co., Ltd 43 participants Est. completion 2024-09-05 54 sites

Other conditions: Gout
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Completed NCT NCT06995339

Comparative Clinical and Biochemical Study Evaluating the Effectiveness of Metformin Versus Febuxostat on Gouty Obese Non-Diabetic Patients

Not yet reported Mostafa Bahaa 60 participants Est. completion 2025-12-30 1 site

Other conditions: Gout
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Completed NCT NCT07033533

Allopurinol and Pathogenesis of Cirrhosis

Not yet reported, Not yet reported Tanta University 100 participants Est. completion 2024-03-01 1 site

Other conditions: Cirrhoses, Liver
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Completed NCT NCT07177898

ALLOPURINOL AND LISINOPRIL FOR DIABETIC KIDNEY PROTECTION: A COMPARATIVE STUDY IN NORMOURICEMIC TYPE 2 DIABETICS

Not yet reported Narowal Medical College 80 participants Est. completion 2024-11-18 1 site

Chronic kidney disease
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Not yet recruiting NCT NCT07326839

Orlistat and Weight Management for Uric Acid Control in Obese Gout: A RCT

Not yet reported XueMei Guo 120 participants Est. completion 2027-11-09 1 site Stand-alone

Other conditions: Gout, Obesity
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Not yet recruiting NCT NCT07369622

HLA-B*58:01-Guided Therapy for Gout: Effectiveness, Safety, and Cost-Effectiveness

Not yet reported Haiphong University of Medicine and Pharmacy 228 participants Est. completion 2028-12-30

Other conditions: Gout Initiating Urate-loweringUrate-lowering Therapy, Gout Arthritis, Gout and Hyperuricemia
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Not yet recruiting NCT NCT07748455

HMA-Venetoclax Induction in Newly Diagnosed AML

Not yet reported Pakistan Blood and Marrow Transplant (PBMT) Group 60 participants Est. completion 2027-12-31 1 site

Other conditions: AML, AML (Acute Myeloid Leukemia)
View official trial listing →

Efficacy history

Not yet reported.

Safety

Not yet reported.

Sources

ClinicalTrials.gov — NCT07089875

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