-
Completed
NCT NCT02488044
A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency
Not yet reported, Not yet reported
Aeglea Biotherapeutics
16 participants
Est. completion 2019-02
9 sites
Stand-alone
Other conditions: Arginase I Deficiency, Hyperargininemia
View official trial listing →
-
Completed
NCT NCT02561234
A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With Advanced Solid Tumors
Not yet reported
Immedica Pharma AB
76 participants
Est. completion 2019-05-28
11 sites
Stand-alone
Other conditions: Advanced Cancers
View official trial listing →
-
Completed
NCT NCT02732184
A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDS
Not yet reported
Immedica Pharma AB
21 participants
Est. completion 2017-11-01
10 sites
Stand-alone
Other conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome
View official trial listing →
-
Completed
NCT NCT03371979
Pegzilarginase and Pembrolizumab for Extensive Disease Small Cell Lung Cancer
Not yet reported, Not yet reported
Aeglea Biotherapeutics
68 participants
Est. completion 2021-01-01
22 sites
Stand-alone
Other conditions: Small-cell Lung Cancer
View official trial listing →
-
Completed
NCT NCT03378531
A Study of AEB1102 (Pegzilarginase) in Patients With Arginase 1 Deficiency
Not yet reported
Immedica Pharma AB
14 participants
Est. completion 2022-12-15
7 sites
Stand-alone
Other conditions: Arginase I Deficiency, Hyperargininemia
View official trial listing →
-
Completed
NCT NCT03921541
Efficacy and Safety of Pegzilarginase in Patients With Arginase 1 Deficiency
Not yet reported
Immedica Pharma AB
32 participants
Est. completion 2023-02-01
32 sites
Stand-alone
Other conditions: Arginase I Deficiency, Hyperargininemia
View official trial listing →
-
Terminated
NCT NCT05676853
A Study of Safety of Weekly Subcutaneous Pegzilarginase in Subjects With Arginase 1 Deficiency
Not yet reported
Aeglea Biotherapeutics
3 participants
Est. completion 2023-04-27
1 site
Stand-alone
Other conditions: Arginase I Deficiency, Hyperargininemia
View official trial listing →
-
Completed
NCT NCT06582524
Pegzilarginase in Subjects <24 Months Old With Arginase 1 Deficiency
Not yet reported
Immedica Pharma AB
3 participants
Est. completion 2025-06-17
3 sites
Stand-alone
Other conditions: Arginase 1 Deficiency
View official trial listing →